Search Term: " Tetra "

	What is CBD?	Darrell Miller	5/15/19
	Multiple studies show using CBD Oil for sleep disorders may be yoursafest bet	VitaNet, LLC Staff	11/6/18
	CBD helps relieve anxiety without the high	Darrell Miller	6/7/18
	Consuming Cannabis Could Slash Your Chances Of Blood Clots, Stroke: Study	Darrell Miller	9/15/17
	Cross Your Fingers—Weed Might Lower Blood Pressure	Darrell Miller	9/4/17
	Can Cannabis Actually Kill Cancer Cells In The Brain?	Darrell Miller	7/26/17
	Help, and hope: Could cannabis possibly help fight cancer?	Darrell Miller	7/21/17
	Is cannabis the cure-all for migraines? Scientists think so	Darrell Miller	7/10/17
	Cannabinoids can successfully kill leukemia cells, reveals groundbreaking new study	Darrell Miller	6/21/17
	Anti-inflammatory Cannabis Compound Useful in Itching, Other Skin Treatment	Darrell Miller	4/23/17
	A New Marijuana To Relieve Pain Without The High	Darrell Miller	1/19/17
	Doctored marijuana gives relief to boy	Darrell Miller	1/17/17
	Top 10 amazing, indigenous, all-natural cures from around the world	Darrell Miller	11/5/16
	Can EDTA help my cardiovascular system	Darrell Miller	10/10/16
	Acne Treatment of Different Skin Types	Darrell Miller	9/20/11
	Lycopene - A Powerful antioxidant with great promise	Darrell Miller	12/10/10
	Folic Acid	Darrell Miller	10/30/08
	Folic Acid	Darrell Miller	8/19/08
	Cetyl Myristoleate	Darrell Miller	5/8/08
	Una de Gato (Cat’s Claw)	Darrell Miller	4/26/08
	Boost digestion with Bifidus Longum and Acidophilus Probiotics	Darrell Miller	3/21/08
	Natural Bar Soaps for the Kitchen and Bathroom	Darrell Miller	1/23/08
	Hemp Bliss (Hemp Milk) from Manitoba Harvest	Darrell Miller	5/31/07
	The Power Plant of the Amazon	Darrell Miller	3/2/07
	Q. What is cat’s claw?	Darrell Miller	11/22/06
	HDL Booster - Boost your good cholesterol	Darrell Miller	3/16/06
	Cholesterol Support FAQ's	Darrell Miller	1/6/06
	AHCC® Fact Sheet - from Now Foods.	Darrell Miller	12/8/05
	TMG Fact Sheet	Darrell Miller	12/7/05
	What is cat’s claw?	Darrell Miller	11/11/05
	Curcumin - Turmeric Extract	Darrell Miller	8/19/05
	CARBON TETRACHLORIDE TESTING AND SILYMARIN	Darrell Miller	7/12/05
	THE DEADLY DEATHCAP MUSHROOM, SILYMARIN, AND LIVER DAMAGE	Darrell Miller	7/12/05
	MILK THISTLE (Silybum marianum)	Darrell Miller	7/12/05
	Ginko: A Natural Antidepressant?	Darrell Miller	6/25/05
	<b> Mushrooms </b>	Darrell Miller	6/10/05
	Red Wine and Resveratrol	Darrell Miller	5/23/05
	Sytrinol -- Natures way to lowering cholesterol up to 40%	Darrell Miller	5/20/05
	Policosanol and cholesterol control ...	Darrell Miller	5/17/05

Date: May 15, 2019 01:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What is CBD?

Cannabidiol (CBD) is a cannabinoid

• Cannabinoids are a class of chemical compounds found in cannabis plants
• CBD is the most prominent cannabinoid found in Hemp
• There are over 100 known cannabinoids found in the various cannabis species
• CBD is NOT psychoactive & helps offset THC
• Tetrahydrocannabinol (THC) is the psychotropic cannabinoid found in cannabis that makes you “high”
• CBD has many health benefits
• Clinical trials with CBD demonstrate improvements from issues including: anxiety, cognition, pain associated with exercise & movement disorders

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Date: November 06, 2018 03:51 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Multiple studies show using CBD Oil for sleep disorders may be yoursafest bet

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Date: June 07, 2018 05:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD helps relieve anxiety without the high

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Date: September 15, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Consuming Cannabis Could Slash Your Chances Of Blood Clots, Stroke: Study

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Date: September 04, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cross Your Fingers—Weed Might Lower Blood Pressure

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Date: July 26, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Can Cannabis Actually Kill Cancer Cells In The Brain?

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Date: July 21, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Help, and hope: Could cannabis possibly help fight cancer?

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Date: July 10, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is cannabis the cure-all for migraines? Scientists think so

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Date: June 21, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cannabinoids can successfully kill leukemia cells, reveals groundbreaking new study

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Date: April 23, 2017 06:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Anti-inflammatory Cannabis Compound Useful in Itching, Other Skin Treatment

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Date: January 19, 2017 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A New Marijuana To Relieve Pain Without The High

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Date: January 17, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Doctored marijuana gives relief to boy

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Date: November 05, 2016 10:54 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Top 10 amazing, indigenous, all-natural cures from around the world

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Date: October 10, 2016 03:14 PM
Author: Darrell Miller
Subject: Can EDTA help my cardiovascular system

EDTA, also referred to as Calcium Disodimum Edathamil, is a synthetic amino acid used to treat a host of conditions including cardiovascular diseases. It can be administered intravenously, intramuscularly or orally.

Primary use: Detox Metals and Clean Veins

The hardening that occurs in our arteries, commonly known as atherosclerosis, contributes massively to poor cardiovascular health. This plaque buildup blocks your arteries causing diseases like high blood pressure, high cholesterol levels and heart attacks. 

 EDTA chelation therapy has been proven to effectively dissolve the plaque restoring the arteries to their previously clear state. The healthy arteries allow good blood flow eliminating cardiovascular diseases.

EDTA is also beneficial in lead poisoning treatment. It has the ability to bind itself to heavy metals like lead, arsenic and mercury in the bloodstream. EDTA treats heavy metal toxicity. It is also used in dentistry during root canals, as well as to remove excess digoxin (the drug used for abnormal heart rhythms) in the body.

Everybody should take EDTA once a year to maintain a health cardiovascular system.

References:

//www.webmd.com/vitamins-supplements/ingredientmono-1032-edta.aspx?activeingredientid=1032&
//umm.edu/health/medical/altmed/supplement/ethylenediamineTetraacetic-acid
//www.life-enhancement.com/magazine/article/531-oral-edta-helps-restore-cardiovascular-function

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Date: September 20, 2011 11:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acne Treatment of Different Skin Types

Not everyone has the same skin type, and if you have acne, then the treatment could be dependent on your skin type. Before discussing the different acne treatments available, therefore, it will be necessary to discuss the various skin types.

Skin types are graded in a number of ways, anything from 3 types to several. Here we shall discuss more than the normal three (oily, dry and normal) but instead look at seven.

1. Normal Skin

Normal skin looks evenly colored and textured, firm and smooth without larger pores. People with normal skin probably had mild acne when at high school, but cleared up fairly quickly during the teenage years without specialized treatment or scarring. Acne in this type of skin normally requires only mild topical treatment and a mild antibiotic face wash to keep the pores clean of dead skin cells.

Treatments designed to reduce sebum production could result in dry skin susceptible to environmental damage. What must be kept in mind is that the prime cause of acne is excessive production of skin oil, correctly known as sebum, becoming mixed with shed skin cells within the sebaceous pores and plugging them. When this plug gets infected with bacteria, the immune system leaps into action to produce puss through leucocytes attacking the bacteria, and inflammation designed to create temperature conditions alien to bacteria.

If you use treatments formulated to reduce sebum production in oily skin, then you might lose the natural skin oil needed to keep your skin waterproof and resistant to the pollution and chemical agents that can cause dermatitis.

2. Dry Skin

If you got through adolescence with few or no skin problems, and you have dry hair and your skin feels dry after washing, then you have dry skin. It is even more important with dry skin that you do not use sebum-reducing treatments, if you even get acne at all. Only the mildest acne treatments should be used if you have dry skin, thought is unlikely that you will get anything other the very mildest case if you really have dry skin.

Your skin can dry through age, so to be of a dry skin type, you should have suffered, or be suffering, these problems while you are 35 years old or under. After that age your skin tends to dry out naturally.

3. Oily Skin

This completes the trilogy of the classic skin types. Oily skin is associated with acne, and if your hair is oily, you tend to tan very easily rather than go red in the sun, and if oily make-ups, such as some foundations, tend to last only a short time, then you likely have oily skin.

You will also have suffered from acne as a teenager, and your skin will have a particular 'look'. It will often appear shiny, and will also seem to have a coarse texture with larger pores than most others seem to have. You will tend to get a lot of blackheads, not only as a teenager.

Oily skin is classically associated with acne, and it is for those with that skin type that classic treatments will be prescribed, such as antibiotics and Accutane.

Apart from these three skin types, there are others that have been defined involving a combination of these and also age.

Sensitive Skin

Sensitive skin is associated with broken blood vessels beneath the surface of the skin, and such skin types should be treated very carefully. If creams or lotions are applied to sensitive skin they should be rubbed in very gently as it could cause bruising.

Sensitive skin is no more susceptible to acne than most other skin types although significantly less so than oily skin. For that reason, treatments for sensitive skin should be similar to that for dry skin or in most cases normal skin.

Combination skin

Combination skin has an oily zone across the forehead, and down the nose and chin, the other areas of the face being normal or dry. Such skin can also be oily along the jaw line and normal to dry everywhere else. In such cases aggressive acne treatment might be necessary in the oily zones, and more mild treatments used in the areas which are normal.

There are three other classes or skin type based upon age or condition, one being mature skin and other ailing skin and the final type, surprise, surprise, being known as acne skin. Ailing skin is caused by skin conditions other than acne, and you should get the advice of a dermatologist if you believe you have this type of skin. Mature skin on the other hand is natural and occurs with age: the skin becomes slack and loose due to a slowing down of cell growth which causes the skin to lose elasticity. There is no cure for this type of skin other than cosmetic surgery, and it is rarely affected by acne.

Acne Skin

Acne skin is normally oily and associated with blackheads, pimples and spots. It is not normally applied to serious acne conditions, being mostly associated with skin which is generally 'spotty', as opposed to mostly clear. It is debatable whether acne skin is any different from oily skin which also tends to be covered with spots and pimples, and the treatments for acne skin are no different to those for oily skin: these are Accutane, antibiotics and topical treatments such as face washes and scrubs.

If you have acne skin you must be careful about the type of cosmetics and face cleansers you use, since either could aggravate your condition. This is not restricted only to those with oily skins of course, since everyone should be aware of the effect of cosmetics and face cleansers on their skin but it is more significant with those who suffer from acne. Cosmetics cannot cause acne, but they can help to aggravate infections which have already occurred.

Although most focus is placed on those with oily skins which are more susceptible to acne, people with any type of skin should consider carefully the types of cosmetic and cleansers which they use. Contrary to what you may have heard or read, acne has nothing to do with your diet - eating fatty foods or chocolates do not cause acne, which is caused only through production of excess sebum, or skin oil, by the sebaceous glands.

Irrespective of your skin type your physician will determine the best treatment that is appropriate for your particular case of acne. This may be different for individuals and may or may not change according to skin type. Antiseptic face washes or scrubs may be appropriate for some acne cases, Accutane might be the best treatment for others, while a course of internal antibiotics such as Tetracyclines may be deemed appropriate for yet other cases.

Treating acne has three distinct phases:

1. Removal of the blackheads and lesions. The removal of lesions can also involve a degree of scar removal, although that is another topic. Black heads, whiteheads and other papules can be treated by the use of facial cleansers and scrubs. They should not be squeezed since the puss inside them could be forced deeper into the skin and so lead to a more generalized infection.

2. Treatment of the bacterial infection. The typical symptoms of acne, the papules, whiteheads and blackheads, are caused by bacterial infection of the plug of sebum and dead skin cells within the sebaceous follicles. The general treatment for such infections is antibiotics, both topically and internally. Tetracycline has already been mentioned as a common internal antibiotic, and several forms of antibiotics are used in facial scrubs of which peroxides and benzoates may perhaps be rather severe for dry and sensitive skins.

3. The third phase is treatment of the causes of excessive sebum production. This is generally not entirely treatable since it is predominantly due to excessive hormonal activity at certain times of your life such as puberty, menstruation, pregnancy and menopause. However, your physician may offer treatments such as the contraceptive pill which should be used with care.

Other treatments include agents that aid desquamation, so preventing the irregular shedding of skin cells that lead to the mixture of sebum and dead skin cells that form the plug that is so easily affected by bacterial infection.

Together these three stages of acne treatment can, if not prevent the condition, certainly reduce its extent and have less of an effect on your skin, particularly if you are the off the oily skin type. Doctors will take your skin type into consideration when determining the best acne treatment for you, although all generally this will only be with respect to topical treatments: treatments that are applied to the surface of your skin.

There are also a number of herbal treatments which are used in the treatment of various stages of acne, and many sufferers find these equally as effective as the more traditional forms of topical applications as prescribed by physicians. However given that the treatment you use is safe according to your physician, any that works for you is the acne treatment that you should likely use, irrespective of your skin type.

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Date: December 10, 2010 06:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lycopene - A Powerful antioxidant with great promise

Lycopene

Lycopene is a Tetraterpene carotene that is largely responsible for the red color of tomatoes and other fruits and vegetables such as carrots and papayas, although it is not a form of Vitamin A as other carotenes are. It is responsible for the production of the pigment beta-carotene which does have Vitamin A activity, and that is also found in carrots and similarly colored foodstuffs.

The health benefits of lycopene have been studied in relation to its possible antioxidant activity and its effect on atherosclerosis and other conditions of the cardiovascular system, and also in its potential anti-cancer properties. Although these properties are still under investigation, there is traditional and anecdotal evidence that is can be used to ward of cancer, heart disease and macular degeneration, a degenerative condition of the retina that results in loss of central vision.

It can be taken as a supplement as a form of insurance, even though the firm medical evidence for its use has yet to be established. While not claiming this to be the case with lycopene, many such traditional uses have eventually been proved to have a firm foundation in science, and many of the initial results and studies with lycopene are tending that way.

The Antioxidant Properties of Lycopene

Carotenoids tend to possess antioxidant properties, and lycopene is as much a carotenoid as the powerfully antioxidant beta-carotene. The problem is that studies focusing specifically on lycopene are rare, and that while such properties can be assumed by association, they have not been conclusively proved for lycopene. Nevertheless, the health benefits of tomatoes are largely assumed to be due to their high lycopene content, particularly powerful when cooked.

Laboratory studies have indicated lycopene to possess strong antioxidant properties, as would also be assumed from its strongly conjugated chemical structure. This would account for its perceived effect upon age-related macular degeneration, and also its possible anti-cancer properties. Several studies have also been carried out using tomato juice in treating atherosclerosis, an oxidative condition involving cholesterol deposition on the internal walls of the arteries.

These studies have been inconclusive, although everything is pointing toward lycopene being a powerful antioxidant displaying all the properties of Vitamin A and perhaps more. A lycopene supplement is believed to be safer than Vitamin A which can be toxic in large quantities (300,000UI +), and lycopene is used as an approved food coloring.

Have you had your Lycopene today?

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Date: October 30, 2008 01:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Folic Acid

National press has recently taken an interest in the benefits of folic acid, with coverage increasing throughout the media. Folic acid, a B vitamin and other folates helps the body to form red blood cells and aids in the formation of genetic material within every body cell. Folic acid also helps to prevent birth defects. Proponents of dietary supplements have encouraged the use of folic acid by women who are of the child-bearing age for a long time.

The public is becoming increasingly aware of the importance of this nutrient to prenatal development. In a survey done by U.S. Health and Human Services in 2007, about 40% of all women surveyed reported the daily consumption of a supplement that contained folic acid, while about 42% of women surveyed reported that folic acid is the most important vitamin for women of child-bearing age. This study also found that awareness of the benefits differed by age group. Younger women were the least likely to know about the benefits of folic acid, and therefore, were the least likely to consume folic acid. These younger women were also more likely to hear about folic acid from a magazine or newspaper or school or college, rather than their health-care provider.

On the contrary, the women who aged 25-34 and 35-47 were much more likely to hear about folic acid and its benefits from their health-care provider. Because of these results, the U.S. Health and Human Services considers it vital to increase young person education and awareness. Folic acid has long been known to help prevent birth defects. Recent research on folic acid shows that it may also help in preventing premature births, boost baby weights, prevent preeclampsia, reduce risk of Alzheimer’s disease, and even cut male smokers’ stroke risk.

Folate is determined from the term “foliage,” and is a member of the B vitamin family where it can be primarily found in dark leafy green vegetables, legumes, citrus fruits, beets, meat, and wheat germ. Folic acid does not occur in nature and cannot be found in unfortified foods. It is not an active form of the B-vitamin. However, it is the most common form of folate used is supplements and in fortified food products due to the fact that it is highly bioavailable and chemically stable. It is also readily reduced to Tetrahydrofolate, which is the active coenzyme form of folate. One study, comparing folic acid from orange juice and folic acid from a supplement showed that the supplement had a better absorption rate than the fortified orange juice.

Although folic acid is not generally associated with side effects, there have been some clinical reports that high level of folic acid can mask a deficiency of vitamin B-12. However, a deficiency of B-12 is very uncommon and it has been determined that only amounts about 3000 – 4000 micrograms per day of folic acid for extended periods of time may have this masking effect, which can in turn be eliminated by supplementing with a few micrograms of B-12. For more information about folic acid and its benefits to your body, contact your local health food retailer.

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Date: August 19, 2008 08:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Folic Acid

Folic acid is an important vitamin to the developing fetus in that it aids cell development, particularly those cells involved in the development of the baby's spine. A deficiency can result in neural tube defects, in which the neural tube, down through which the central nervous system passes, fails to close properly.

However, let's first discuss the substance itself so that its function in that process can be more easily understood. Neither should we ignore the other benefits that folic acid gives us, or the problems we can have in the event of a deficiency.

Folic acid is a form of Vitamin B9, sometimes referred to as Vitamin M. Its anionic form is known as folate, which is the form in which it is frequently offered in supplements. Incidentally, it gets its name from the Latin for leaf, so is from the same root as foliage. It is water soluble, and like Vitamin C can be leached through the body if not immediately used.

It is available naturally from leafy and green vegetables such as lettuce, broccoli, spinach and peas, but is also available in fortified breakfast cereals, sunflower seeds and some fruits. You would not normally suffer a deficiency, but if you are taking anticonvulsants, have liver problems or undergoing kidney dialysis, then you might need a supplement. Pregnancy, of course, is the important case in which a supplement should be taken, although, surprisingly, many mothers-to-be are unaware of this.

New body cells need folate for their production, particularly when they are dividing and growing rapidly such as during pregnancy and in infancy. The formation of DNA depends on many chemical entities, among them four nitrogenous bases, of which three, thymine and the two purine bases, adenine and guanine, depend on folate for their synthesis. If the growing fetus is lacking folate then DNA synthesis will be hindered. This retards cell division and growth.

Among the conditions this can cause are a form of anemia known as megaloblastic anemia, and neural tube deficiencies, where the sheath that surrounds the main nerve canal up the spine fails to close properly. The best known of such neural tube defects is spina bifida, though any condition caused by a lack of cell division can also occur. Anemia can be contracted by both adults and children, since production of red blood cells takes place constantly throughout your lifetime. These are the reasons why folic acid or folate is used in breakfast cereals.

The biochemistry is fairly simple to understand, and is important because it explains the importance of two other B vitamins, B3 and B12, in DNA synthesis. The initial stages are a six step reaction that forms methyl Tetrahydrofolate from folate, starting with the reduction of folate to dihydrofolate, and then a further reduction to the Tetrahydrofolate (THF). Vitamin B3 (in the form of nicotinamide adenine dinucleotide phosphate) is an essential cofactor for these reductions. Vitamin B12 is necessary as an acceptor for the methyl-THF so that it can continue along the biochemical pathway - now that is too complex to discuss here!

However, the inference you can rightly draw from this is that a deficiency of Vitamin B12 can cause what is known as a 'methyl trap', whereby the methy-THF cannot be used, and so a deficiency in Vitamin B12 can lead to the same symptoms as a folic acid or folate deficiency.

The implications of that are that vitamin B12 is also an essential component of a pregnant woman's diet. The problem here is that this vitamin is available only from animal sources, including dairy products. Its presence in vegetable organisms such as certain algae and fungi has been proposed, but it is believed that the cobalamin (chemical term for the vitamin) from these sources is not bioavailable to humans.

Vegans, therefore, who do not eat dairy products, will need a Vitamin B12 supplement in addition to folic acid or folate, particularly when they are pregnant and with young growing children. In this respect, a vegan diet is unsuitable for young children until their rapid growth period has stabilized.

For those of you wondering why the biochemistry above was discussed: that is your answer. Such discussions can frequently explain why certain supplements are necessary, or certain diets should be reconsidered under particular circumstances. Such things are easier to understand and accept when the logic behind them are explained. A folic acid supplement taken from the onset of pregnancy up to 12 weeks at least, and also a Vitamin B12 supplement in the case of those with a low meat intake, should prevent neural tube defects such as spina bifida.

A daily supplement of 0.4 mg should be sufficient, along with a diet rich in green vegetables, fortified cereals and breads and oranges. Your greens are best steamed since prolonged boiling destroys folic acid - as it destroys Vitamin C. One source of folic acid that you might read about is liver, and its additional iron content might lead you to believe this to be a good component of your diet when pregnant. However, although normally a very nutritious food, liver should be avoided during pregnancy due to its high Vitamin A content. This can be harmful to your baby.

Finally, there are some circumstances under which the dose during pregnancy should be greater. If you have previously had a child with a neural tube defect, or have an NTD yourself (or your partner), if you are diabetic, if you have celiac disease (a gluten allergy) or are taking anti-epileptic medication, you should increase your dose to 5 mg (milligrams) for which you will likely need a prescription from your physician.

NTD is rare, so don't over-worry much about it, but take the above precautions to put your mind at rest since pregnancy is not a time during which you should be nervous but to enjoy. That will pass on to your growing baby, which will then itself be happy.

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Date: May 08, 2008 03:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cetyl Myristoleate

Cetyl myristoleate is a fatty acid ester used largely as a dietary supplement to support joint mobility and the immune system. Chemically it is a natural hexadecyl ester of cis-9-Tetradecanoic acid, an unsaturated fatty acid commonly known as myristoleic acid.

The acid is found naturally in fish and whale oils, and also in butter and kombo butter from the kombo nut. The ester is of a buttery consistency at normal room temperatures, and turns waxy when cooled, and it has no known uses other than as a health supplement, particularly for the treatment of arthritis and other inflammatory and immune system problems.

The substances appear to have similar therapeutic characteristics to unsaturated essential fatty acids, but with a stronger and more long lasting effect. It also appears to work in three distinctly different ways in that it acts as a joint lubricant, supports the immune system and functions in the same way as essential fatty acids.

Arthritis is a disease that has reached epidemic proportions worldwide, and it is estimated that more than 50 million Americans are affected by it. Until recently it was believed to be a disease of the aged, or associated with physical injury, but is now known to be more complex than that, with many manifestations and causes. Because of this, no single treatment is effective with all forms of arthritis, but cetyl myristoleate is the new kid on the block that is believe to make a significant contribution to the treatment of non-infective forms of the disease.

However, it was not always known, and a search in the textbooks for cetyl myristoleate prior to 1977 would have yielded nothing. Why 1977? It started with Harry W Diehl, a sugar chemist with an interest in the treatment of arthritis. While carrying out research on arthritis in mice, he was working on thin layer chromatographic analysis of a methylene chloride extract of macerated mice. He noticed a separation that was unknown to him, which was subsequently identified as cetyl myristoleate.

He had been unable to induce arthritis in mice, and believed that if he found out how to do that, then he should also be able to establish what made the mice immune to the disease, and so establish a cure. He soon established that it was this cetyl myristoleate circulating in the blood that protected the mice, and then found a way of synthesizing it in the lab by esterifying myristoleic acid.

Since the compound was unknown at that time Diehl patented it in 1977, hence the date. Apart from in mice, it has subsequently been found only in whale oil and in one of the glands of the male beaver, with no other known sources at the time of writing. There have been several studies that have supported the effect of cetyl myristoleate on arthritis, the first human study being in 1995 when 46 out of 48 arthritis patients showed significant improvement in articular mobility and reduction in pain. Others since have demonstrated similar results.

So how does it work? What is the mechanism by which this hitherto unknown substance helps to relieve the symptoms of osteo and rheumatoid arthritis? Being a fatty acid ester, cetyl myristoleate possesses lubricant properties, and one of its properties is to supplement the synovial fluid that lubricates the joints and tendons. This helps to keep the joints moving freely, and reduces their tendency to grind when the connective tissue wears. It also lubricates entire muscle groups, allowing them to slide over each other more freely, and also over bones allowing a smoother movement of the joints.

The second way, in which it operates, by supporting the immune system, is particularly appropriate to the treatment of rheumatoid arthritis which is caused by the immune system attacking the body’s own joint and connective tissue. In this respect, cetyl myristoleate has also been found effective in treating other immune system conditions such as multiple sclerosis and lupus erythematosus.

Finally, it also possesses the mediation effect on the inflammatory reaction possessed by other essential fatty acids. This helps to reduce the effect of inflammation that causes much of the swelling and pain of arthritic conditions, although it occurs much faster than with other fatty acids. When taken together, all of these effects have a powerful effect in reducing the unpleasant symptoms of both osteoarthritis and rheumatoid arthritis. Swelling is reduced, mobility is improved and pain is alleviated. Improvements have been reported by sufferers of both types of arthritis, and in fact it is reported that Harry Diehl successfully treated his own arthritis with the substance before any other human tests had been carried out.

Cetyl Myristoleate is now used word-wide in significant quantities, and there have as yet been no confirmed reports of adverse side effects. However, as with many otherwise safe supplements, it is recommended not to be taken by pregnant or lactating women until it has been proved to definitely have no side effects on the fetus or young babies.

Although there is no definitive scientific evidence of the effectiveness of the substance in relieving the symptoms of arthritis, there is an overwhelming body of evidence from those that have used it world wide. The accepted treatment is by non-steroidal anti-inflammatory drugs (NSAIDs), and with over 16,0000 NSAID-related deaths in the USA alone each year, cetyl myristoleate is certainly worth considering as an alternative for arthritis sufferers. Not only that but there is a very significant price differential, with NSAIDs costing 5 – 10 times that of cetyl myristoleate.

Among the other benefits that people using the substance have reported are beneficial effects on psoriasis, hepatitis, high blood pressure, eczema, allergies, headaches and many more. Although many of these might be coincidence or psychosomatic, it cannot just be coincidence that many of them, such as psoriasis and allergies, are related to the immune system.

However, anybody with asthma or a history of severe allergic reactions should consult their physician before using the substance. That aside, there is more than enough popular evidence to indicate that cetyl myristoleate is effective in the treatment of arthritis in all its forms, and also good for your general state of health and wellness.

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Date: April 26, 2008 09:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Una de Gato (Cat’s Claw)

Una de Gato, otherwise known as cat’s claw, is properly Unicaria tomentosa. It has been used as an herbal medicine for at least two thousand years by the people of Central and South America who gave it the name vilcacora.

It grows in jungle areas and rainforest in South America and Asia, and gets its name from the small claw-like thorns at the base of the leaves. One of the environmental benefits of the Una de Gato is that when it is harvested at three feet above the ground, it grows back to its full size of up to 100 feet within a few years when it can be harvested again to three feet. Cat’s claw has been given dietary supplement status by the FDA.

The Peruvian Asháninka tribe has used the plant as a contraceptive and for the treatment of rheumatic conditions, diabetes, acne, diarrhea, cancer, urinary tract diseases and as an anti-inflammatory, and many of the studies of cat’s claw have centered on this tribe. The studies quickly showed the active ingredients to be alkaloids, both tertracyclic oxindole alkaloids and pentacyclic alkaloids that have been found both in the bark and in the root.

The extract is obtained by boiling both the inner part of the bark and the root, each of which differs in concentration of the various alkaloids. The root is believed to better for its anti-inflammatory powers due to the quinovic acid glycoside it contains, although the relative concentrations of the various alkaloids can vary according to the time of year and to the chemotype of the plant.

Cat’s Claw comes in two chemotypes, each of which differs in the relative concentrations of the two different alkaloid types. One predominates in the pentacyclic alkaloids that strengthen the immune system, and the other chemotype in the Tetracyclic alkaloids that counter that effect and reduce the speed and strength of the contractions of the heart. It is not possible to tell which chemotype a particular plant is until it has been chemically tested. They look exactly the same and it is possible for both to grow sided by side. However, the root is generally richer in alkaloids, and sells at about twice the price of the bark. Alkaloids are not the only active ingredients in Una de Gato, and it also contains tannins and phytochemicals that have an antioxidant effect and are useful free radical scavengers. They have been studied for their effects in the treatment of HIV and cancer, though mainly due to the glycoside content that will be discussed shortly. The National cancer Institute has confirmed some anti-cancer properties of quinovic glycosides derived from cat’s claw.

The four pentacyclic alkaloids have been found to have a boosting effect on the human immune system, which it does by enhancing the ability of the white blood cells and macrophages to digest and kill off foreign organisms and debris in tissue and the bloodstream. The inference is that the herb is able to be used to treat a wide variety of infectious diseases, including many immune and autoimmune conditions including AIDS. The results with AIDs are inconclusive, although one particular study showed that cat’s claw produced accelerated healing of cold sores and genital herpes (herpes simplex virus) and shingles (caused by herpes zoster virus). Although the evidence is slight, there are indications of its possible use in treating viral conditions.

It is used in homeopathy for the treatment of a number of digestive ailments, such as Crohn’s disease, leaky bowel syndrome, colitis, gastritis and gastric ulcers among others. It is also used in the treatment of inflammatory conditions such as arthritis, rheumatism and some conditions of the prostate gland.

The tertracyclic indole alkaloids that appear to counter the immune-boosting properties of their pentacyclic cousins include rhynchophylline, hirsutine, and mitraphylline. Rhynchophylline prevents blood clots in the veins and arteries by reducing the formation of platelets, and can dilate the peripheral blood vessels of the hands and feet. It can also lower blood cholesterol levels and reduce the heart rate. Due to this effect on blood vessels, it is though to be able to improve the circulation in the brain and be a useful treatment for Alzheimer’s sufferers. Hirsutine inhibits contractions of the smooth muscle of the bladder, and so finds uses in the treatment of urinary incontinence.

The pentacyclic alkaloids pteropodine and isopteropodine are believed to have important properties beyond their phagocytosis effect on the immune system. It has been reported that they have an effect on the 5-HT(2) receptors in the brain. These neurotransmitters are used as targets for many drugs used to treat a variety of conditions such as depression, eating disorders and anxiety, and such alkaloids have a positive modulating effect on them.

The anti-inflammatory properties of cat’s claw are largely due to the very potent quinovic acid glycosides previously referred to. These have been known about only recently, and they are thought to work synergistically to reduce the tissue swelling (edema) associated with the immune system’s inflammatory reaction. Although this is believed to be largely due to the glycosides, three of the alkaloids also possess anti-inflammatory properties. This property provides the scientific background for the traditional use of Una de Gato for rheumatism and arthritis, both inflammatory conditions. Many of the digestive conditions for which the plant has traditionally used are also inflammatory in nature.

A threat to cat’s claw is the destruction of the Peruvian rainforest, although not as much as a threat as the destruction of the plant itself. Cat’s claw has reached levels of popularity so high that it is in danger of extinction due to improper harvesting. New laws being enacted by the Peruvian government should help to protect the plant, and to promote its harvesting over cocoa.

When buying cat’s claw, make sure that it is the Uncaria tomentosa form you are purchasing since there is another type, Uncaria Guianensis that contains different alkaloids and is not as potent as the real Una de Gato. Also beware of a shrub known as cat’s claw acacia, grown in Mexico and the southwest USA, since it contains cyanide derivatives and could be very dangerous if taken by mouth.

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Date: March 21, 2008 12:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost digestion with Bifidus Longum and Acidophilus Probiotics

Prior to discussing how you can boost digestion with bifidus longum probiotics, let's first have a look at probiotics in general and why they are so beneficial to us.

Probiotics are also known as microflora, and are beneficial organisms that live in your digestive tract. Not all microorganisms are bad news, and many are essential for good health. Included in these organisms are various types of bacteria and yeasts, each of which has a specific part to play in the proper functioning of your body. Because of this they are found in foods all over the world, including yoghurt and fermented vegetables such as German sauerkraut and Korean kimchi.

Among their major benefits to health are that they help to support your immune system, they aid the digestion and absorption of food, they provide increased energy by improving the metabolic conversion of blood glucose to energy, and they can also help to delay aging. However, you should be aware that not all probiotics are the same, and when used properly some can have the same effect as antibiotics.

They are used to cure many digestive problems such as irritable bowel syndrome and diarrhea, and can also help to relieve heartburn and acid reflux. In fact your lower intestine should contain a minimum of 85% friendly bacteria, and 15% at most of unfriendly bacteria that can cause disease if they over-colonize your colon. It might surprise you to learn that you have around twenty times more bacteria in your body than body cells.

One of the best known of the probiotics are members of the lactobacillus family that are contained in yoghurt and curds and whey, so Little Miss Muffet had the right idea. However, you might not have the right idea in eating commercial yoghurt because, while raw yoghurt does contain these helpful bacteria, the type that you buy in pots in the supermarkets has likely been pasteurized - a process that kills off the bacteria. Unless the product has been seeded with live bacteria after pasteurization, then there will likely be none in your yoghurt! Make your own!

So what are the probiotics that do you most good, and in what form should you consume them? The common friendly bacteria are the already mentioned lactobaccilus, and then lactococcus, streptococcus thermophilus, enterococcus, bifidobacterium and others. Bacteria are easily killed off by the acidic conditions in your stomach, and since they must be taken live they should be consumed in a form that can resist the stomach acid.

There are many ways in which they benefit you, the main ones that are currently understood being:

Lactic acid production: the presence of lactic acid in the gut prevents stops or slows the growth of harmful bacteria by increasing the acidity. Some probiotics, known as lactic acid bacteria (LAB) can do this. Most bacteria do not like acidic conditions.

Supporting the immune system: LAB bacteria have been shown to increase the production of cytokines that stimulate the activity of the macrophages that attack foreign viruses and pathogenic bacteria. The LAB also promotes the formation of NK-cells (natural killer cells) that destroy cells that have been infected by viruses.

Adhesion site blockage: bacteria attach themselves to your intestinal walls at specific adhesion sites. Friendly bacteria can colonize these sites and so prevent the pathogens from adhering.

Effect on the Intestinal wall: the intestinal wall has a natural mucous barrier that helps to prevent the passage of allergens and pathogens into the bloodstream through the intestine. Probiotics can strengthen this barrier, and also alter the nature of the mucous to render it less liable to penetration by these unwelcome visitors.

So where does bifidobacteria come into this? There is a number of strains of this bacterium living in the human body, but Bifidus longum is the most common or most abundant of these. Although it is the most common bacterium found in commercially available probiotic products, high numbers have to be consumed for the proper health benefits. However, commercial yoghurts contain very little of this bacterium, or even none at all. This is largely due to the pasteurization previously discussed, that kills the bacteria at high temperatures. Unfortunately this process is not selective, and in ridding the products of bacteria that could make you seriously ill, the beneficial bacteria are also destroyed.

This is a shame because Bifidus longum has been shown to inhibit E.Coli that can cause serious conditions of the digestive system. Among these are severe diarrhea and an inflammatory condition in the colon as the immune system tries to expel these nasty bacteria. This bacterium is particularly dangerous to the weak, such as the aged, children and people already weakened by illness.

It also helps to counteract yeast and other vaginal infections and when taken with other probiotics is believed to help in colon cancer cases. Among its other benefits are its part in the biosynthesis of thiamine, riboflavin and other vitamin B forms in your intestine, and also the absorption and assimilation of these vitamins by your body. It is also believed that it might help to reduce the cholesterol level in your body through its uptake of bile salts from the colon.

The major destructive elements of Bifidus longus are antibiotics of any kind, whether they be penicillin variants or Tetracycline, and although the latter is used mainly for infections of the respiratory tract, it is ingested by the gut and effectively reduces the population of the bacteria that are needed for optimum health. That is one of the reasons why antibiotic use should be restricted to only what is necessary, and not use indiscriminately for all infections. Unless administered intravenously or site targeted, antibiotics kill off the good with the bad!

The other activities of Bifidus longus, such as removing the by-products of our metabolism that could be toxic if left to roam our bodies, render this bacterium as useful to your body as any vitamin or mineral supplement you could take. It is a supplement that many either overlook or are not even aware of, yet one that can make a significant difference, not only to your digestive and intestinal health, but also to you general overall wellbeing.

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Date: January 23, 2008 11:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Bar Soaps for the Kitchen and Bathroom

Good natural bar soaps that contain only substances that are good for your skin are available, although most people pay little attention to them. Many people might be unaware of the fact but the skin is the largest organ of the body. As such, the skin needs taken care of just as much as any other major organ, yet few people pay much attention to what they bring into contact with it. Although a lot of money is spent on body products, do you really know what your skin needs for optimum health and what substances can do it harm?

Your skin carries out many functions other than keeping the bits inside that should be kept inside. It is a natural thermostat, containing the sweat glands that dampens it and allows evaporation to cool you down. It contains hairs and subcutaneous fat, both of which help you to remain warm when the external temperature is low. Your skin is designed to remain supple, and so allow free movement of the various parts of your body.

It is an ideal waterproof covering for your body that also protects you from infection. Although infection can set in if the skin is ruptured through cuts or grazes, the skin itself rarely suffers from surface infections when related to the number of infectious agents it is constantly in contact with.

The health of your skin is very important, especially in view of the fact that it regularly comes into contact with some very hazardous substances. What may not have occurred to you is that one of the many functions of your skin is to eliminate some of the body’s waste products. It does this when you sweat and the toxins that are emitted can harm it. Although not often infected, it does suffer from complaints such as psoriasis, eczema and acne that are not primarily caused by bacterial agents or viruses, and hence not true infections.

These conditions, however, are caused largely through the emission of toxic agents through the sweat glands. Acne for instance is caused by excessive emission of sebum that combines with dead skin cells to form acne which can also become infected with bacteria. Psoriasis is the excessive formation of skin cells at too rapid a rate, the true causes of which are as yet unknown. Skin cells can become cancerous due to excessive exposure to sunlight or ultra violet radiation, and skin cancer is the most common type of cancer that your doctor is liable to come across.

If you suffer from any specific skin condition, such as acne, or even dry skin that can be caused through excessive exposure to degreasing agents or dry winds, then your skin will need special care. The soap you use is very important in the way you care for your skin, and many people will use soaps that contain many ingredients that they cannot pronounce let alone understand.

Your skin needs cleansed regularly since it comes into contact with many dangerous and toxic substances. Apart from the everyday pollution of traffic fumes and factory emissions, there are also the substances that contaminate your skin at work and at home. At home specially, domestic cleaners can be very harsh on your skin, consisting of substances that are intended to clean away greases and oils, the very types of substance that protect your skin from the elements. When you clean your oven or your sink without gloves, you also clean off the protective oily layer on your skin and leave it open to bacterial attack.

Your skin can also become sensitized to many substances, so that whenever it comes into contact with them it promotes an allergic reaction that can cause irritations so severe that your life can become very miserable. Many people are allergic to various types of soap or detergent because they have become sensitized to them, and are unable to use that type of cleanser after sensitization.

Many soaps contain active ingredients that are intended to carry out specific functions. Thus, some contain antibacterial agents to inhibit the growth of specific types of bacteria on your skin, while others contain detergents to improve their cleaning power. However, some detergents can be very harsh on your skin, and try to avoid bar soaps containing PEG-6 methyl ether or butylated hydroxytoluene (BHT). These can be harmful to your skin. There are others, and if your skin is sensitive try to avoid soaps containing animal products or petroleum derivatives.

Take Tetrasodium EDTA, which is present in common bar soaps. It enhances the penetration of substances through your skin, which means that it can also enhance the penetration of the lees welcome ingredients in the soap as well as the moisturizers. Substances as sodium etidronate that is a synthetic preservative that might cause irritation to your skin and mucus membranes. There are several other synthetic detergents that are ingredients in bar soaps, and many kitchen soaps contain the same ingredients as personal or bathroom soaps, the difference between them being only in their moisturizer and perfume content.

Other ingredients than can cause potential problems are limonene, linalool and camphor, all of which can give rise to unwelcome conditions such as irritation or respiratory problems. The first two of these are common in bar soaps, as are benzaldehyde and benzyl alcohol which are irritants. Alpha-pinene, found in some bar soaps, is a sensitizer than can damage your immune system. Unless you know what a specific ingredient is, don’t use the soap. Instead you should use pure natural bar soaps containing antioxidants that are good for your skin.

A pure soap should contain the fat or oil that it is made from, good examples being coconut or palm oils, water, a water softener to enable the soap to cleanse the skin properly, an example being one of the penetrates, a moisturizer such as glycerine or lanolin and possibly a perfume derived from natural sources. Salt is also frequently used, and is a good bactericide.

Wherever possibly, you should choose a natural soap containing antioxidants. Citrus soaps, for example, contain vitamin C although many soaps contain antioxidants such as beta carotenes, vitamin A and vitamin E. Since soap consists of both oils and water, you can have both oil and water soluble antioxidants in your soap. The antioxidants help to protect your skin from the ravages of pollution and the effects of the sun’s rays, both of which generate free radicals that can accelerate the aging and wrinkling of your skin.

A good antioxidant, moisturizer and wetting agent in your bar soap will help to protect your skin from the effects of atmospheric pollutants, the drying effect of the sun and wind and also effectively cleanse the skin surface and pores of everyday dirt. If this is associated with an absence of synthetic chemicals that can cause irritation then you will be giving your skin the best protection that you can. This is true of soaps intended either for the kitchen or the bathroom.

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Date: May 31, 2007 12:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hemp Bliss (Hemp Milk) from Manitoba Harvest

Hemp Bliss (Hemp Milk) Hemp pioneers launch organic hemp milk The new Hemp Bliss organic hemp milk, by Manitoba Harvest, offers a nutritious alternative to dairy, soy, and grain based drinks. Offered in chocolate, vanilla, and original varieties, Hemp Bliss has a nutty undertone and naturally provides a boost of 1,200 mg Omega-3 and 5g or protein per serving. Made from fresh organic hemp seeds and organic ingredients, hemp bliss has a rich, creamy and smooth taste. A 32 oz Tetra pack is discounted at VitaNet 25% OFF MSRP. Listed as lactose-free, soy-free, nut-free and cholesterol-free, Hemp Bliss is ideal for those with allergies or sensitivities to dairy, nut, grain and soy-based beverages. Currently a large and growing trend in the market place, hemp foods are becoming increasingly popular for their health benefits, their strong digestible protein profile and their abundance of fiber, vitamins and minerals. Manitoba Harvest process the raw hemp seed into USDA Certified Organic: hemp seed oil, shelled hemp seed, hemp seed butter, and hemp protein powder. You cereal lovers can now enjoy cereal again with Hemp Bliss. -- Buy Organic Hemp Bliss 32oz at Vitanet LLC

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Date: March 02, 2007 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Power Plant of the Amazon

Enzymatic Therapy Amazon Herbs

It may surprise most Americans to know that rainforest plants are the original source for one-fourth of the chemotherapy medications used today. Plants offer a plethora of beneficial compounds, and rainforests contain a superabundance of beneficial plants.

In fact, plant medicines are the most widely used medicines of all types in the world. Over eighty-five percent of the world’s population uses plant and herbal medicines as their primary medicines. That’s 5.1 billion (5,100,000,000) people worldwide! While Americans overwhelmingly use synthetically manufactured pharmaceuticals to cure their ills, the vast majority of Earth’s inhabitants use healing plant medicines instead.

One of the most powerful healing rainforest plant medicines is cat’s claw, or Uncaria tomentosa. This high climbing woody vine grows at the base of tall trees in the Peruvian rainforest. The plant’s claw-shaped thorns latch onto the trees and spiral further upward, nourished by the lush rainforest environment. For over 2,000 years, the Ashaninka, a tribal people of the Peruvian rainforest, have used the root of U. tomentosa to treat illnesses in the tribe, including asthma, bladder infections, infected wounds, arthritis, bone pain, bowel inflammation, and cancer.

Q. I’ve heard about cat’s claw, but what does it do and how do I know which one is right for me?

Cat’s claw might be one of the most confusing (and most effective!) nutritional supplements available in health food stores today. One reason that it’s so confusing is there are so many kinds of cat’s claw supplements-there are cat’s claw leaves, cat’s claw bark, and even cat’s claw twigs. While each of these supplements claim to help the immune system, it is the root of Uncaria tomentosa that is proven to impart the true cat’s claw health benefits.

Scientists, who have extensively studied every part of the plant, discovered that extracts made from selected cat’s claw roots possess the healing power to treat and prevent diseases like cancer, rheumatoid arthritis, ulcers and degenerative diseases. In addition, it demonstrates anti-inflammatory, anti-viral and anti-microbial benefits.

Adding to the confusion is the fact that not all Uncaria tomentosa roots actually contain healing properties.

Healers in the Ashaninka tribe attribute the healing properties in cat’s claw to the “good spirits” that live in the plant’s roots. The Ashaninka healers, or sancoshi, are able to actually “see” the good spirits hidden inside the root of the plant before they harvest them.

Some cat’s claw plant roots have the good spirits. Some don’t. If the good spirits are mixed with any cat’s claw root without good spirits, the healing power is lost. While there are no apparent differences in the plants or the roots to the untrained eye, only certain cat’s claw roots possess the power to heal. And, for a very long time, only the Ashaninka tribal healer seemed to be able to identify them. They call the good spirit cat’s claw Saventaro, or “powerful plant”.

However, scientists who were given cat’s claw roots by the Ashaninka to study in the laboratory discovered that they could “see” the good spirits, too! Using high performance liquid chromatography, or HPLC, a laboratory process that identifies various chemical compounds, the good spirits of cat’s claw roots were revealed to be important medicinal compounds called pentacyclic oxindole alkaloids (POAs). Research has learned that POAs provide powerful benefits for the human immune response.

Q. Why are good spirits, or POA’s, good for the immune system?

Cat’s claw POAs work to keep us healthy by directly interacting with white blood cells, the backbone of our immune system. Our white blood cells are the disease fighting cells of the human body. These highly specialized cells fight diseases we catch, such as colds and flu, as well as diseases that start within our own cells, such as cancer and autoimmune diseases. There are many kinds of white blood cells; each has a specific job to do in fighting diseases.

Certain POAs help white blood cells called macrophages work faster. The macrophages’ job is to engulf and digest foreign material. This means that macrophages can ingest m ore bacteria and disease causing microbes when they are exposed to POAs. The scientists also discovered that POA cat’s claw extract increases the production of a chemical protein called interleukin that is secreted by macrophages. This macrophage-secreted interleukin (IL-1) has important immune enhancing properties. IL-1 alerts resting white blood cells and spurs them into action. It also helps make other biochemicals that are essential to an activated immune system.

POAs also help B cells. B cells are white blood cells that make antibodies that kill germs. Each B cell is programmed to make one specific antibody that is effective against one specific germ (such as a bacteria, virus, or fungus). When scientists looked at the number of B cells after they were exposed to POA cat’s claw root extract, they found that the B cells had increased significantly, resulting in an increased supply of antibodies. And perhaps most importantly as they relate to cancer, the POAs in cat’s claw root extract help increase the number of T cells, the true soldiers of the immune system. There are many different kinds of these white blood cells, including Helper T cells, Suppressor T cells, and Killer T cells. Increased Helper, Suppressor, and Killer T-cells can more effectively destroy cancer cells. Increasing the number of circulating T-cells is very important in a disease like AIDS as well.

Q. Can cat’s claw and other plants in the rainforest really cure diseases? Isn’t that just folklore?

It’s folk use and modern science combined-plants have long been known for their ability to kill cancer cells. In fact, the National Cancer Institute (NCI) has identified over 3000 plant extracts that can kill cancer cells. More than 70 percent of these plants are found only in the rainforest.

Q. What is it about the rainforest that gives plants like cat’s claw these cancer killing compounds?

Most of the time when we talk about rainforests, we’re talking about the tropical rainforests. While other forests, like the old-growth temperate forests of the Pacific Northwest, also have high rainfalls and tall trees, the tropical rainforests located near the equator are where most plant medicines come from.

The Amazon rainforest in South America is the world’s largest, covering an area about two-thirds the size of the continental United States. Depending on the elevation and distance to the equator the Amazon rainforest receives between 160 and 400 inches of rain per year. The rain is spread pretty evenly from January to December-it’s always the rainy season-and the temperatures remain between 75-80 degrees Fahrenheit all year.

This fertile environment continually recycles itself. When leaves fall from the trees, flowers wilt, and animals die in the rainforest-all of the nutrients are recycled back into the roots of the trees and plants. Because the rainforest reuses almost everything that falls to the ground, the plant growth is amazingly rich in alkaloids and other medicinal compounds. Researchers think these compounds and alkaloids, like POAs, protect the plants from illness and insect attacks. These are the very same compounds that protect us from disease.

Q. When the Ashaninka harvest the cat’s claw roots, does it impact the rest of the plant?

No. The Ashaninka work intelligently to keep rainforest cat’s claw plants perpetually healthy. The Ashaninka employ responsible and innovative harvesting techniques to keep the plants alive and tribal members healthy. Individual cat’s claw plants are never completely harvested. Only one third of the lateral roots are collected at any one time to allow re-growth by the remaining root. Once a plant’s lateral roots have been partially harvested, that plant is left to regenerate, and no more root is harvested from it for 10 years.

Q. Why are the Ashaninka willing to share their cat’s claw?

They are generous people. The Ashaninka see no benefit in hoarding cat’s claw for themselves alone. They also want to make sure that the plant’s healing properties continue on. As their homelands continue to be destroyed by deforestation, rainforest peoples are also disappearing. There were an estimated ten million tribal and indigenous peoples living in the Amazonian Rainforest in 1510. Today there are less than 200,000.

Since the 1900’s more than 90 indigenous tribes have died out and disappeared. Each time a rainforest medicine man or woman dies without passing their arts on to the next generation, the tribe and the world loses thousands of years of irreplaceable knowledge about medicinal plants. With them, centuries of accumulated knowledge of the medicinal value of rainforest species have been lost.

A good example of the impact of this loss can be seen in cat’s claw. When European explorers began venturing into the Amazon River basin, t hey were skeptical of the stories the Ashaninka people told them of U. tomentosa’s amazing healing powers. But when the explorers became sick with colds, flu, or other illnesses, they harvested cat’s claw root for themselves and gave the plant a try. Sometimes the explorers got better when they used the cat’s claw root, sometimes they stayed the same.

Q. Why didn’t the cat’s claw root help all the explorers?

Because some cat’s claw plant roots have good spirits-POAs-and some cat’s claw plant roots have Tetracyclic oxindole alkaloids, or TOAs. While the POAs have very powerful effects in the immune system, the TOAs have different effects in the body, none of which help the immune system cells at all. All U. tomentosa plants look virtually identical, so it’s hard to tell if they have the healing POAs or non-helpful TOAs.

What makes cat’s claw identification even more challenging is the fact that plants with POAs one year will have TOAs the next. Cat’s claw plants seem to change their alkaloid chemotypes at will, an incredibly powerful accomplishment for a plant to possess. Harvesting of cat’s claw roots that contain POAs is very tricky. Unless the person gathering the root extract is an Ashaninka sancoshi. These medicine men know which cat’s claw to use; they can actually “see” the good spirits hidden inside the root. When scientists studying cat’s claw discovered they could “see” presence of TOAs using HPLC technology, they were able to harvest cat’s claw root extracts with POAs that consistently helps people get and stay healthy.

Q. Do some cat’s claw root extract supplements contain TOAs?

Yes they do. And buying those products will only benefit the cat’s claw distributor; they won’t help you stay healthy. When cat’s claw root is harvested from the rainforest, responsible supplement maker examine the root with HPLC to make sure that only POA roots are collected. But, this identification of the chemotypes takes significant time and costs money. For these reasons, many cat’s claw distributors don’t include this important process in their harvesting. The POAs and TOAs are simply just mixed together and sold as a cat’s claw product with no mention of any alkaloid content on the label.

Q. Why should I avoid TOAs?

While the POAs in cat’s claw root extracts have numerous benefits to the immune system, the TOAs have different effects in the body, none helping the immune system cells. Most importantly, however, when POAs and TOAs are mixed together, the TOAs actually work against the POAs. TOAs reduce the capacity of POAs to beneficially modulate the immune system.

Q. How can I be sure the cat’s claw I buy is POA cat’s claw?

Read the label of the cat’s claw root extract product you are considering buying. If it does not clearly state that it is the high POA cat’s claw, then chances are that it’s not.

Q. What do the Ashaninka receive in return for the cat’s claw harvesting?

The Ashaninka and reputable distributors of cat’s claw root extract have established a mutual and ethical relationship. Both groups benefit from the sale of the plant material. Maintaining this relationship is important for both the tribe and the distributors.

The distributors are paying a fair price for the raw material directly to the tribe. No intermediary is involved. This payment covers the raw material itself, a license-fee for the k knowledge of the plant, and a guarantee (from both sides) of a lasting relationship. Payment is also made for the protection of the rainforest. No deforestation is allowed. The area where the cat’s claw materials are processed is also leased and payment is made for this, as well.

This arrangement allows the Ashaninka to make independent decisions in how to spend this income from sale of their cat’s claw plants. They have been able to make improvements in the tribe’s water supply and in their living areas. They are also able to obtain outside medical aid as needed and provide for education of their children.

The partnership with cat’s claw distributors has created a sustainable resource for the Ashaninka. The tribe has been able to not only preserve their rainforest, but also compete financially with unsustainable income sources offered by timber and agricultural firms.

Q. Why is it important to preserve the rainforest?

The most amazing fact about these impressive medicinal plants is the vast number that5 has yet to be discovered. In fact, the rainforest’s abundance is one reason it is home to so many healing plants. Within a four square mile patch of rainforest, you could see 1500 species of flowering plants, 750 species of trees, 125 mammal species, 400 species of birds, 100 reptile species, 60 amphibian species, and 150 different species of butterflies.

Unfortunately, not everyone looks to the rainforest for the same reasons. Many consider its real value in board feet and cultivated acreage. The forces pushing industrial development move quickly; experts estimate that we’re losing over 130 plant, animal, and insect species every day/ That amount to almost 50,000 species a year.

A combination of logging, petroleum interests, cattle grazing operations, and, of course, our own consumer appetites are putting pressure on rainforest resources. The consequences are sobering:

• Rainforests once covered 14% of the earth’s land surface; it’s only 6% today
• The last remaining rainforests could be consumed in less than 40 years.
• Nearly half of the world’s species of plants, animals and microorganisms will be destroyed or severely threatened over the next quarter century due to rainforest deforestation.

By leaving the rainforest intact, however, and harvesting its many nuts, fruits, oil-producing, and medicinal plants, the rainforest has more economic value than if it was cut down for timber or to make grazing land for cattle. If managed properly, the rainforest can provide the world’s need for sustainably harvested natural resources on a perpetual basis. That’s what the Ashaninka are doing with their cat’s claw harvesting.

Conclusion

The discovery of medicinal plants is dependent upon healthy rainforests. When an acre of tropical rainforest is lost due to deforestation, the impact on the number of plant and animal species lost and their possible uses is staggering.

We can all help the development of sustainable rainforest industries. By purchasing renewable and sustainable rainforest products, like POA type cat’s claw root extract, we are keeping rainforests alive and well. By benefiting from the innate wisdom of the Ashaninka people we are keeping ourselves just as alive and well. By honoring the science and the sacred of the world’s rainforests, like my friend the oncology nurse, the massive wealth and diversity will be there for generations to come.

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Buy Herbs to boost health and sex drive at Vitanet ®

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Date: November 22, 2006 01:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Q. What is cat’s claw?

A. Cat’s claw might be one of the most confusing (and most effective!) nutritional supplements available in health food stores today-with some fairly good reasons.

First its mere name can be bewildering. Currently, there are at least 16 plants in the world that are called cat’s claw. Sometimes these plants are referred to as “Una de Gato”, Spanish for cat’s claw. While Uncaria tomentosa is the Latin name of the plant most frequently sold as cat’s claw supplements, these products vary vastly. Some cat’s claw nutritional supplements contain cat’s claw bark, some contain cat’s claw stems, and others contain compounds from the leaves of cat’s claw. All of these claim to help the immune system. However, it is the root of Uncaria tomentosa that actually contains the true cat’s claw health benefits. Scientists, who have extensively studied every part of the plant, discovered that only extracts made from cat’s claw root possess the healing power to treat and prevent disease. While it would seem that this vital understanding might help clear up some cat’s claw confusion, not all Uncaria tomentosa roots actually contain healing properties.

To determine which cat’s claw roots do have healing properties, we have to go to the rainforests of Peru. This is where Uncaria tomentosa thrives. It’s a woody vine that’s found at the base of tall trees in the rainforests. As the plant grows, it winds up and around the tree, attaching itself to the trunk with curved cat-like claws found at the junctions of its leaves. The Ashaninka Indians, who make these rainforests their home, have used the roots of the cat’s claw plant for thousands of years to cure illness and maintain health in the tribe.

Healers in the Ashaninka tribe attribute the healing properties in cat’s claw to the “good spirits” that live in the plant’s roots. In order to obtain these healing properties, the correct cat’s claw root must first be harvested. The Ashaninka healers know which cat’s claw to use; they can actually “see” the good spirits hidden inside the root of the plant before they collect them. Some cat’s claw plant roots have the good spirit. Some cat’s claw plant roots don’t. If the cat’s claw root with good spirits is mixed with any cat’s claw root without good spirits, the healing power is lost. While there are no visible differences in the plants or the roots, only certain cat’s claw roots possess the power to heal. And, only the Ashaninka tribal healers seem to be able to see them.

Amazingly, however, scientists who were given cat’s claw roots by the Ashaninka to study in the laboratory discovered that they were able to “see” the good spirits, too! Using high performance liquid chromatography, or HPLC, a laboratory process that identifies various chemical compounds, the good spirits of cat’s claw roots were revealed to actually be important medicinal compounds, called pentacyclic oxindole alkaloids (or POAs).

At the same time, the scientists studying cat’s claw found they could “see” the non-healing properties as well. Again, using HPLC, they also discovered the presence of Tetracyclic oxindole alkaloids (or TOAs) in certain cat’s claw roots. While the POAs have very powerful effects in the immune system, the TOAs have different effects in the body, none of which help the immune system cells at all.

And, if the TOAs and POAs are mixed together (as so often happens in the vast majority of cat’s claw products), the resulting product is useless to healing and health. The TOAs cancel out the action of the POAs, making the cat’s claw root extract ineffective. Even as little as 1% TOA content can cause POAs to lose their ability to beneficially modulate the immune system.

This means that cat’s claw supplements that contain only POAs (in other words, cat’s claw that is 100% TOA-free) from the root of the plant will provide powerful effects in the immune system.

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Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1238)

Date: January 06, 2006 12:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cholesterol Support FAQ's

Cholesterol Support FAQ's What ingredients does NOW® Cholesterol Support contain, and how many capsules should I take daily? NOW® Cholesterol Support is specially formulated to support your body’s normal metabolization of cholesterol. This supplement contains essential nutrients like Vitamins C & E, and Tocotrienols derived from natural source Vitamin E. The active ingredients include Chromium, Guggul Extract, and PureGar® Garlic, specialized dietary ingredients that work synergistically to support healthy cholesterol metabolism. Has the formula for NOW® Cholesterol Support been changed? Recently the U.S. FDA ruled that Red Rice Yeast extract has a drug effect on the body and has banned dietary supplements from containing this ingredient. In order for NOW® to continue to offer Cholesterol Support with Red Rice Yeast extract, we would have to register this supplement as a drug, which would entail years of clinical trials. Due to the complications associated with this ingredient, NOW® has decided to reformulate this top seller. We’ve increased the levels of certain key nutrients to account for the absence of Red Rice Yeast extract, and this new formulation is as effective as the original. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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Support Healthy cholesterol at Vitanet

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Date: December 08, 2005 10:20 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: AHCC® Fact Sheet - from Now Foods.

AHCC® Fact Sheet

LIKELY USERS: People needing increased activity of their Natural Killer cells; People seeking improved immune system response; People with a need for tissue repair; People with oxidative challenges; People seeking to increase liver function People defying aging or with a need to improve cellular integrity.

KEY INGREDIENTS: AHCC® (Active Hexose Correlated Compound)

MAIN PRODUCT FEATURES: AHCC® is a proprietary extract produced from specially cultivated and hybridized mushrooms. According to extensive research in humans, as well as numerous non-clinical studies, AHCC®supports immune system function through its effects on macrophages and NK (Natural Killer) Cells. NK cells and the intercellular mediators they produce are critical for the maintenance of healthy cell cycle function. AHCCR® has also been shown possess antioxidant properties, and supports healthy liver function.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: AHCC® (Active Hexose Correlated Compound) is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product.

AHCC® is a rich source of polysaccharides such as beta glucan 1,3 and activated hemicellulose produced by enzymatic modification of organic medicinal mushrooms, including shiitake. It also has been shown to support normal levels of macrophages and cytokines, further strengthening the immune system.

This formula is suitable for vegetarians and is offered in Vcaps.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, take 2 Vcaps® 3 times daily, preferably on an empty stomach.

COMPLEMENTARY PRODUCTS: Antioxidants, Astragalus, Colostrum, Dr. Verghese Liver Formula, Immune Renew, Indole-3-Carbinol (I3C), Inositol Hexaphosphate (IP-6),

CAUTIONS: None.

PRODUCT SPECIFIC: None

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems. Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

DISCLAIMER: Information given here may vary from what is shown on the product label because this represents my own professional knowledge and understanding of the science underlying the formula and ingredients. The information in this review should not be used as diagnosis, prescription or as a specific product claim.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G. (2003) Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infectin in mice in the hindlimb-unloading model of spaceflight conditions. J Appl Physiol 95:491-496.

Burikhanov RB, Wakame K, Igarashi Y, Wang S, Matsuzaki S (2000) Suppressive Effect of Active Hexose Correlated Compound (AHCC®) on Thymic Apoptosis Induced by Dexamethasone in the Rat. Endocrine Regulations 34:181-188. Matsui Y, et al. (2002) Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study. J Hepatol. 2002 Jul;37(1):78-86. PMID: 12076865 Matsushita K, et al. (1998) Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anti-Cancer Drugs 9:343-350. Sun B, Wakame K, Mukoda T, Toyoshima A. Kanazawa T, Kosuna K (1997) Preventive Effects of AHCC® on Carbon Tetrachloride Induced Liver Injury in Mice. Nat Med 51(4):310-315.

Ye SF, Ichimura K, Wakame K, Ohe M. Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress. Life Sci. 2003 Dec 19;74(5):593-602. PMID: 14623030 Ye SF, Wakame K, Ichura K, Matsuzaki S (2004) Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat. Endocr Regul 38(1):7-13.

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AHCC and Vitanet Great Combination

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Date: December 07, 2005 02:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: TMG Fact Sheet

TMG Fact Sheet

LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.

MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.

TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.

Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.

ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.

TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.

DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.

SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.

COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.

People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.

This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

General:

Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791

Methylation:

Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review].

Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30.

Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review].

Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.

Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.

Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.

Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

Homocysteine:

Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.

Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361

Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203

Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.

Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methyleneTetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.

Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.

Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499

Liver function:

Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].

Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.

Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.

Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329

Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277

Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon Tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.

Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887

Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612

Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.

McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907

Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon Tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.

Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439

Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].

Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644

Autism & Seizures:

Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.

Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.

Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.

Immunity:

Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.

Safety:

Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=988)

Date: November 11, 2005 05:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is cat’s claw?

Q. What is cat’s claw?

A. Cat’s claw might be one of the most confusing (and most effective!) nutritional supplements available in health food stores today-with some fairly good reasons.

First, its mere name can be bewildering. Currently, there are at least 16 plants in the world that are called cat’s claw. Sometimes these plants are referred to as “Una de Gato”, Spanish for cat’s claw. While Uncaria tomentosa is the Latin name of the plant most frequently sold as cat’s claw supplements, these products vary vastly. Some cat’s claw nutritional supplements contain cat’s claw bark, some contain cat’s claw stems, and others contain compounds from the leaves of cat’s claw. All of these claim to help the immune system.

However, it is the root of Uncaria tomentosa that actually contains the true cat’s claw health benefits. Scientists, who have extensively studied every part of the plant, discovered that only extracts made from cat’s claw root possess the healing power to treat and prevent disease. While it would seem that this vital understanding might help clear up some cat’s claw confusion, not all Uncaria tomentosa roots actually contain healing properties.

To determine which cat’s claw roots do have healing properties, we have to go to the rainforests of Peru. This is where Uncaria tomentosa thrives. It’s a woody vine that’s found at the base of tall trees in the rainforests. As the plant grows, it winds up and around the tree, attaching itself to the trunk with curved cat-like claws found at the junctions of its leaves. The Ashaninka Indians, who make these rainforests their home, have used the roots of the cat’s claw plant for thousands of years to cure illness and maintain health in the tribe.

Healers in the Ashaninka tribe attribute the healing properties in cat’s claw to the “good sprits” that live in the plant’s roots. In order to obtain these healing properties, the correct cat’s claw root must first be harvested. The Ashaninka healers know which cat’s claw to use; they can actually “see” the good spirits hidden inside the root of the plant before they collect them. Some cat’s claw plant roots have the good spirits. Some cat’s claw plant roots don’t. If the cat’s claw root with good spirits is mixed with any cat’s claw root without good spirits, the healing power is lost. While there are no visible differences in the plants or the roots, only certain cat’s claw roots possess the power to heal. And, only the Ashaninka tribal healers seem to be able to see them.

Amazingly, however, scientists who were given cat’s claw roots by the Ashaninka to study in the laboratory discovered that they were able to “see” the good spirits, too! Using high performance liquid chromatography, or HPLC, a laboratory process that identifies various chemical compounds, the good spirits of cat’s claw roots were revealed to actually be important medicinal compounds, called pentacyclic oxindole alkaloids (or POAs).

At the same time, the scientists studying cat’s claw found they could “see” the non-healing properties as well. Again, using HPLC, they also discovered the presence of Tetracyclic oxindole alkaloids (or TOAs) in certain cat’s claw roots. While the POAs have very powerful effects in the immune system, the TOAs have different effects in the body, none of which help the immune system cells at all.

And, if the TOAs and POAs are mixed together (as, so often happens in the vast majority of cat’s claw products), the resulting product is useless to healing and health. The TOAs cancel out the action of the POAs, making the cat’s claw root extract ineffective. Even as little as 1% TOA content can cause POAs to lose their ability to beneficially modulate the immune system.

This means that cat’s claw supplements that contain only POAs (in other words, cat’s claw that is 100% TOA-free) from the root of the plant will provide powerful effects in the immune system.

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Date: August 19, 2005 12:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curcumin - Turmeric Extract

Curcumin

Turmeric- History and Traditional Usage

Native to Southeast Asia, Curcuma longa is a tall
tropical shrub with large oblong leaves and pale yellow flowers.
The genus “Curcuma” belongs to the Zingiberaceae family, which
includes ginger.1 The plant possesses a large root structure
with fleshy, bulbous underground parts called “rhizomes.” These
rhizomes, known as turmeric root, are harvested at maturity,
dried and cured for commercial use. Chemical analysis shows that
dried turmeric contains essential and volatile oils, with a
curcuminoid content of 2.5 to 5.0 %.2

In addition to its
popularity as a spice, turmeric is used as a dye for cloth and
coloring agent in foods and cosmetics, thanks to its rich yellow
color. Turmeric also serves as a preservative, probably owing to
the antioxidant and antimicrobial properties of curcumin.
Extracts of Curcuma longa have demonstrated in vitro
antibacterial and anti-fungal effects.3

Turmeric is named in
ancient Ayurvedic and Chinese herbal texts as a traditional folk
remedy. Historically, turmeric was used externally for wounds,
and sprains, and internally for digestive complaints,
rheumatism, liver disorders, coughs and colds.4
Benefits

Protects cells and tissues by fighting free radicals.*

Supports joint function*

The numerous beneficial
effects attributed to turmeric stem in large measure from the
antioxidant properties of curcumin. Antioxidants neutralize free
radicals, which are highly unstable molecules that can damage
cellular structures through abnormal oxidative reactions.
Curcumin is a potent “scavenger” of the superoxide radical, a
free radical that initiates potentially harmful oxidative
processes such as lipid peroxidation.5 Through this activity,
curcumin has been shown to protect skin cells from the injurious
effect of nitroblue Tetrazolium, a toxin that generates
superoxide radicals. Curcumin also increases survival of cells
exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
which stimulates superoxide and hydrogen peroxide production.
Curcumin itself is not toxic to cells, even at high
concentrations. Pure curcumin was shown to be less protective
than a mixture of curcuminoids, indicating a possible synergism
among curcuminoids.6 Because free radicals are involved in aging
and exert harmful effects on skin, these results suggest
curcumin may help slow skin aging.

Curcumin demonstrates
several other in vitro effects linked to free radical
scavenging. Curcumin scavenges nitric oxide, a compound
associated with the body’s inflammatory response.7 Pure curcumin
and turmeric extracts protect red blood cells from lipid
peroxidation induced by hydrogen peroxide.8 Curcumin has been
shown to protect DNA from oxidative damage, inhibit binding of
toxic metabolites to DNA, and reduce DNA mutations in the Ames’
test.9 Although additional studies suggest an anticarcinogenic
effect of curcumin, through protection of DNA,10 one in vitro
study found that curcumin induced DNA damage in human gastric
mucosal cells.11 It is speculated that curcumin may act as a
pro-oxidant in the presence of transition metal ions such as
copper and iron. (This is true for other antioxidants, including
vitamin C.) Curcumin also demonstrates in vitro inhibition of
COX-I and COX-II enzymes, which are involved in the inflammatory
reaction.12 Together these results strongly suggest that
curcumin is a potent bioprotectant with a potentially wide range
of therapeutic applications.

Animal studies- In vivo protective effects

Through its free radical scavenging
properties, curcumin has shown bioprotective effects in animals.
In one study, rats were treated with isoproterenol, a chemical
that causes cardiac hypertrophy (enlargement of the heart) due
to abnormal collagen metabolism. Co-treatment with curcumin
reversed the degradation of collagen and cardiac hypertrophy
induced by isoproterenol.13 Curcumin protects mice from
detrimental effects of radiation, by stabilizing the glyoxalase
system, a biological system that regulates cell division.14
Curcumin protects livers of rats from the damaging effects of
carbon Tetrachloride (CCl4), a potent hepatoxin that injures the
liver via its free radical metabolite, CCl3.15,16 Curcumin
protected rats from alcohol-induced brain damage, in a study in
which oral administration of curcumin reversed lipid
peroxidation, reduced levels of free-radical metabolites and
increased levels of glutathione, a major physiologic
antioxidant.17 Curcuma longa extracts have shown
anti-inflammatory effects in rats.18

Human Trials

Curcumin exhibits free-radical scavenging ability when
administered to humans. In an open trial (uncontrolled), 18
healthy individuals ranging in age from 27 to 67 years consumed
a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
for 45 days. Before and after blood tests showed a statistically
significant decrease in lipid peroxides.19 Preliminary trials
have tested the anti-inflammatory action of curcumin, with
results that verify the traditional use of turmeric as an
anti-rheumatic herb. In a short-term double-blind, cross-over,
comparative study, 18 people received curcumin (1200 mg daily)
or phenylbutazone for two week periods. Both curcumin and
phenylbutazone produced measurable improvements in joint
flexibility and walking time. The subjects reported results only
with phenylbutazone, which may be explained by the short
duration of the trial.20 In a small placebo-controlled trial
comparing curcumin to phenylbutazone, 45 patients with
post-operative inflammation received curcumin, phenylbutazone or
placebo. The anti-inflammatory effects of curcumin and
phenylbutazone were comparable and superior to placebo.21
Curcumin has not been found to produce an analgesic (pain
relieving) effect.

Bioperine-Nature’s Absorption Enhancer
Boosts Curcumin Absorption*

Traditional Ayurvedic herbal
formulas often include black pepper and long pepper as
synergistic herbs. The active ingredient in both black pepper
and long pepper is the alkaloid, piperine. Experiments carried
out to evaluate the scientific basis for the use of peppers have
shown that piperine significantly enhances bioavailability when
consumed with other substances.22 Several double-blind clinical
studies have confirmed that Bioperine® increases absorption of
nutrients.23

Curcumin is poorly absorbed in the intestinal
tract, limiting its therapeutic effectiveness. Oral doses are
largely excreted in feces, and only trace amounts appear in the
blood. Concomitant administration of 20 mg of piperine with 2
grams of curcumin increases the bioavailability of curcumin by
2000%.24

Scientific References

1. Majeed, M., Badmaev,
V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
Piscataway, NJ: NutriScience Publishers.
2. Srimal, R.C.
Turmeric: a brief review of its medicinal properties.
Fitoterapia 1997;68(6):483-93.
3. Ammon, H.P.T., Wahl, M.A.
Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
4.
Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
The Protocol Journal of Botanical Medicine, Autumn
1995:43-46.
5. Rao, N.S., Rao, M.N.A. Free radical scavenging
activity of curcuminoids. Arzneim.-Forsch./Drug Res.
1996;46(2):169-171.
6. Bonté. F. et al. Protective effect of
curcuminoids on epidermal skin cells under free oxygen radical
stress. Planta Medica 1997;63:265-66.
7. Rao, S., Rao, M.N.A.
Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol.
1997;49:105-7.
8. Lalitha, S., Selvam, R. Prevention of
H2Os-induced red blood cell lipid peroxidation by aqueous
extracted turmeric. Asia Pacific J Clin Nutr
1999;8(2):113-14.
9. Deshpande, S.S., Maru, G.B. Effects of
curcumin on the formation of benzo[a]pyrene derived DNA adducts
in vitro. Cancer Letters 1995;96:71-80.
10. Subramanian, M., et
al. Diminution of singlet oxygen-induced DNA damage by curcumin
and related antioxidants. Mutation Research
1994;311:249-55.
11. Blasiak, J., Trzeciak, A., Kowalik, J.
Curcumin damages DNA in human gastric mucosa cells and
lymphocytes. Journal of Environmental Pathology, Toxicology and
Oncology 1999;18(4):271-76.
12. Ramsewak, R.S., DeWitt, D.L.,
Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
activities of Curcumins I-III from Curcuma longa. Phytomedicine
2000;7(4):303-308.
13. Nirmala, C. Anand, S., Puvanakrishnan,
R. Curcumin treatment modulates collagen metabolism in
isoproterenol induced myocardial necrosis in rats. Molecular and
Cellular Biochemistry 1999;197:31-37.
14. Choudhary, D.,
Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
system by curcumin. Journal of Ethnopharmacology
1999;64:1-7.
15. Park, E-J. et al. Protective effect of
curcumin in rat liver injury induced by carbon Tetrachloride. J
Pharm. Pharmacol. 2000;52:437-40.
16. Deshpande, U.R. et al.
Protective effect of turmeric (Curcuma longa L.) extract on
carbon Tetrachloride-induced liver damage in rats. Indian
Journal of Experimental Biology 1998;36:573-77.
17.
Rajakrishnan, V. et al. Neuroprotective role of curcumin from
Curcuma longa on ethanol-induced brain damage. Phytotherapy
Research 1999;13:571-74.
18. Arora, R.B. Basu, N., Kapoor, V.,
Jain, A.P. Anti-inflammatory studies on Curcuma longa
(Turmeric). Indian J Med Res 1971;59(8):1289-95.
19.
Ramirez-Bosca, A. et al. Antioxidant curcuma extracts decrease
the blood peroxide levels of human subjects. Age
1995;18:167-69.
20. Deodhar, S.D., Sethi, R. Srimal. R.C.
Preliminary study on antirheumatic activity of curcumin
(diferoyl methane). Indian J Med Res 1980;71:632-34.
21.
Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
anti-inflammatory property of curcumin (diferoyl methane) in
patients with postoperative inflammation. International Journal
of Clinical Pharmacology, Therapy and Toxicolgy
1986;24(12):651-54.
22. Atal, C., Zutshi, U., Rao, P.
Scientific evidence on the role of Ayurvedic herbals on
bioavailability of drugs. Journal of Ethnopharmacology
1981;4:229-232.
23. Bioperine®–Nature's Bioavailability
Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
Corporation, Piscataway, N.J.
24. Shoba, G., et al. Influence
of piperine on the pharmacokinetics of curcumin in animals and
human volunteers. Planta Medica 1998;64(4):353-6.

© 2002
Doctor's Best, Inc. Revised 8/13/02

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Date: July 12, 2005 09:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CARBON TetraCHLORIDE TESTING AND SILYMARIN

CARBON TetraCHLORIDE TESTING AND SILYMARIN

Carbon Tetrachloride is used in laboratory tests to assess the ability of a substance to actually protect the liver from any potentially damaging compound. Increasing the dosages of carbon Tetrachloride takes the liver through fatty infiltration, fibrosis and eventually cirrhosis. During these tests, administering Milk Thistle extract resulted in effective protection of liver tissue from the toxic effects of the chemical.

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Date: July 12, 2005 09:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: THE DEADLY DEATHCAP MUSHROOM, SILYMARIN, AND LIVER DAMAGE

THE DEADLY DEATHCAP MUSHROOM AND SILYMARIN

The protective action of Silymarin in the liver has been confirmed through several experimental and clinical studies. Animals who have had their livers exposed to toxic chemicals such as carbon Tetrachloride, amanita toxin (deadly mushroom) and galactosamine were protected from damage by Milk Thistle.3 Animals who had their livers partially removed experienced some organ regeneration when treated with Milk Thistle.

In the 1970’s, additional research on the ability of Milk Thistle to de-toxify liver cells of deadly mushro o m poisoning was conducted. The poison of this mushroom is extremely toxic and usually results in death within two to five hours. Amantine causes severe hemorrhagic liver dystrophy and inevitable death. Even when the studies were undertaken, scientists did not expect Milk Thistle to offer any significant protection against such a volatile and deadly toxin. The two peptides which comprise the poison are the most potent liver damaging substances currently known. Sixty patients who had severe amanita poisoning in Europe were treated with Milk Thistle. The results were impressive.

In experiments where silymarin was given before the amanita toxin was ingested, it was 100 percent effective in preventing liver toxicity.4 If given within ten minutes, it still neutralized the poison. Even after 24 hours, it was found to prevent death and liver damage.5

Not only did Milk Thistle protect the liver fro m amantine damage, it also helped to prevent the loss of weight normally seen in animals that have ingested the poison. The impressive results of these tests resulted in stepped up production of Milk Thistle extract, which has made it much more available now.

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Date: July 12, 2005 09:45 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: MILK THISTLE (Silybum marianum)

MILK THISTLE (Silybum marianum)

COMMON NAMES: Christ’s Crown, Holy Thistle, Venus Thistle, Heal Thistle, Wand of God’s Grace PLANT PARTS: ripe seeds, or extract from the shell

ACTIVE COMPOUNDS: Seed extract contains a complex of three flavanolignans which are collectively referred to as silymarin. These flavonoid-like compounds are silibin, silychristin and silydianin.

PHARMACOLOGY: The flavonoids contained in Milk Thistle have a strong liver protective action and have been extensively used in Europe as pharmaceutical p reparations for liver disorders. These include: silibin, silydianin and silychristin, which all combine to create silymarin. Clinical trials have shown that silymarin can protect the liver by counteracting a number of toxic substances including alcohol, acetaminophen, carbon Tetrachloride and the Amanita mushroom poison.

Apparently, silymarin actually alters liver cell membranes which prevent toxins from passing through the cell. It inhibits the release or the synthesis of certain enzymes which are toxic to liver tissue. In addition, these compounds stimulate cellular growth and reproduction by boosting protein synthesis. Milk Thistle seeds are also high in betaine hydrochloride, which may contribute to the hepato-protective properties of the plant.

Silymarin has also exhibited significant antioxidant capabilities and can help reduce inflammation by inhibiting certain enzymes. The seeds of the plants appear to have the highest concentration of silymarin.

VITAMIN AND MINERAL CONTENT: rich in bioflavonoids CHARACTER: hepato-tonic, alterative, demulcent and protective BODY SYSTEMS TARGETED: liver, gallbladder, pancreas and stomach.

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Date: June 25, 2005 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ginko: A Natural Antidepressant?

Ginko: A Natural Antidepressant?

Several health practitioners are looking at ginkgo as a possible natural substitute for some pharmaceutical antidepressants. Be cause ginkgo stimulates the brain through increased oxygen availability, it may have therapeutic value in some cases of depression. Depression is viewed by some doctors as a condition of brain “sleepiness.” By increasing mental alertness, ginkgo may help to snap a depressed brain out of its mental patterns by stimulating biochemical reactions at the cellular level. Ginkgo may inadvertently work the same way that exercise does for people suffering from depression. Exercise helps to oxygenate the blood and by so doing, elevates mood. Ginkgo accomplishes a similar action by boosting brain blood flow. Ginkgo has also been recommended in combination with antidepressant drugs such as tricyclics and Tetracyclics. It should be noted that tests using ginkgo to treat depression used higher than normal dosages of ginkgo. Learning disabilities may also benefit from the neuro-stimulation ginkgo provides, however, no one has studied its effects in this area.

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Date: June 10, 2005 10:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mushrooms

Mushrooms by Frank Sturges Energy Times, December 7, 1999

The interest in mushrooms as health enhancers has... mushroomed. Mushrooms, researchers have found, are filled with a long list of substances that may help us fight disease. Some of these natural chemicals boost immunity. Others may be effective against cancer and heart disease.

One of the most remarkable aspects of the research into mushrooms stems from the vast number of mushrooms that dot the landscape. At least 1.5 million types of fungi populate forests, fields, nooks and crannies, but studies have detailed the properties of less than 3,000.

Compound Interest

Mushrooms produce so many beneficial compounds because they constantly fight off other fungi and microbes to survive. These substances, which mushrooms utilize for defense, can apparently help humans.

One of the most important of these classes of compounds are the polysaccharides. Scientists believe these long starch molecules spark immune action that can protect us against invading germs or cancer. They may do this by persuading the body to create what are called killer T-cells. These immune warriors destroy microscopic invaders and may help stop tumors.

According to Paul Stamets, author of Growing Gourmet and Medicinal Mushrooms (Ten Speed), use of polysaccharides... "will synergistically, in combination with the individual's immune system, result in dramatic recoveries...Right now we don't clearly understand all the elements in those formulas to be able to predict downstream what will happen. But clearly with some people, it is tremendously effective" (Townsend Ltr, 6/98).

In addition, mushrooms also make biologically active chemicals called steroids and terpenes, says Christopher Hobbs, author of Medicinal Mushrooms (Interweave). These substances are thought to help fight off the formation of cancerous tumors.

Maitake: Useful Fungus

Maitake (Grifola frondosa) mushrooms, also known as "Hen of the woods," contain chemicals called beta glucans that can enhance immunity. Scientists are particularly fascinated by substances called the "D-fraction." Studies show these can spur immunity (Biol. Pharm. Bull. 17(12), Dec. 1994: 1554-60).

Researchers are also looking into the possibility that Maitake can help people with AIDS regain weight. And scientists are examining their effect on high blood pressure and diabetes.

Reishi's Effects

In Tibet, the Reishi mushroom (Ganoderma lucidum) has long been used to battle altitude sickness in the Himalayan mountains. Reishi is also reputed to soothe frayed nerves.

Scientific studies have supported these traditional uses, finding that people who consumed Reishi functioned better in low oxygen (Proceedings Contrib Symp 59 AB, 5th Intl Cong, 8/14-21, 101-104). Other research finds Reishi may help ease arthritis (Proc 1st Intl Symp on Ganoderma l. 11/17-18, 99-103, Tokyo).

Lion's Mane

Lion's Mane (Heri-cium erinaceus), also called "Monkey's head," has traditionally been a treatment for stomach problems in China. But researchers have found that chemicals in this mushroom help fight tumors (Biosci Biotech Biochem 56(2), Feb. 1992: 347-8).

During the past few years, scientific investigators have also begun to extract chemicals called erinacines from lion's mane. These substances, (known as Nerve Growth Stimulant factor) appear to encourage neuron regeneration. The potential uses: boosting nerve performance, fixing neurological damage and treating Alzheimer's disease (Tetrahedron Ltrs 35(10), 1994: 1569-1572).

Divine Fungus

Known as Cogmelo de Deus (Mushroom of God) in Brazil, the Royal Agaricus (Agaricus blazei) has been grown in Japan since the '70s where it enjoys widespread popularity. Researchers find that it provokes powerful anti-tumor effects. This fungus harbors more beta-glucans, immunity enhancers, than other mushrooms.

Mushroom Performance

Can a fungus make athletes faster? A few researchers think so, pointing to Chinese Olympians who use Cordyceps sinensis. This fungus, traditionally grown on caterpillars, is another native of the Himalayas.

Traditionally, Cordyceps has been used to foster stamina, better breathing and immunity.

At least one study shows this fungus may help blood vessels dilate during exercise. By supplying extra blood to working muscles, Cordyceps may help fight off fatigue and boost performance (Abstracts from 5th Mycological Cong, Vancouver, 8/14-21).

Research Extravaganza

The mushroom called Shiitake has been the subject of an extravagant amount of research since the '60s. Called the "elixir of life," it boosts immunity. Stamets reports that people with cancer who take Shiitake do significantly better in coping with their disease (Abstract 2nd Meeting Soc of Natl Immunity, Italy, 5/25/94).

Another characteristic of Shiitake mushrooms: a celebrated taste. The tongue and the palate take great pleasure in this health enhancer!

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Date: May 23, 2005 09:20 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Red Wine and Resveratrol

The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis:

Implications for protection against coronary heart disease Authors: Pace-Asciak, Cecil R.a; Hahn, Susanb; Diamandis, Eleftherios P.b; Soleas, Georgec; Goldberg, David M. Affiliations: a. Department of Pharmacology, University of Toronto and Research Institute, Hospital for Sick Children, Toronto, Canada b. Department of Clinical Biochemistry, University of Toronto, 100 College Street, Banting Institute, Toronto, Ontario, M5G 1L5, Canada c. Andres Wines Ltd., Grimsby, Ontario, Canada Keywords: Atherosclerosis; Thromboxane B2; Hepoxilins; Anti-oxidants; Resveratrol; Quercetin

Abstract:

A number of lines of evidence suggest that red wine may be more effective than other alcoholic beverages in decreasing the risk of coronary heart disease (CHD) mortality. This protection over and above that due to ethanol itself may be explained by phenolic components with which red wines are richly endowed. We have studied the effects of the trihydroxy stilbenetrans -resveratrol on human platelet aggregation and on the synthesis of three eicosanoids from arachidonate by platelets, i.e. thromboxane B2 (TxB2), hydroxyheptadecatrienoate (HHT) and 12-hydroxyeicosaTetraenoate (12-HETE). These effects were compared with the actions of other wine phenolics (quercetin, catechin and epicatechin) and antioxidants (a-tocopherol, hydroquinone and butylated hydroxytoluene). trans-Resveratrol and quercetin demonstrated a dose-dependent inhibition of both thrombin-induced and ADP-induced platelet aggregation, whereas ethanol inhibited only thrombin-induced aggregation. The other compounds tested were inactive. trans-Resveratrol also inhibited the synthesis of TxB2, HHT, and to a lesser extent 12-HETE, from arachidonate in a dose-dependent manner. Quercetin inhibited only 12-HETE synthesis, and hydroquinone caused slight inhibition of TxB2 synthesis, the remaining compounds being ineffective. De-alcoholized red wines inhibited platelet aggregation; their ability to inhibit the synthesis of TxB2 but not that of 12-HETE from labelled arachidonate by washed human platelets was proportional to their trans-resveratrol concentration. These results are consistent with the notion that trans-resveratrol may contribute to the presumed protective role of red wine against atherosclerosis and CHD.

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Date: May 20, 2005 12:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Sytrinol -- Natures way to lowering cholesterol up to 40%

In a Lab experiment, cholesterol was lowered by 40%

Abstract

Formulations contg. citrus polymethoxylated flavones (PMF), mainly tangeretin, or citrus flavanone glucosides hesperidin and naringin were evaluated for blood cholesterol-lowering potential in hamsters with diet-induced hypercholesterolemia. PMF metabolites were also investigated. Diets contg. 1% PMF decreased blood serum total and very-low-d. lipoprotein (VLDL) + LDL cholesterol by 19-27 and 32-40%, resp., and decreased serum triacylglycerol levels. Comparable decreases were achieved by feeding 3% mixt. of hesperidin and naringin (1:1), implying lower hypolipidemic potency of the hesperidin/naringin mixt. vs. PMF. HPLC-MS anal. identified high blood serum, liver, and urine concns. of tangeretin metabolites, including dihydroxytrimethoxyflavone and monohydroxyTetramethoxyflavone glucuronides and aglycons. The total liver concns. of tangeretin derivs. corresponded to hypolipidemic concns. of intact tangeretin in earlier expts. in vitro. PMF may be novel flavonoids with cholesterol- and triacylglycerol-lowering potential. Elevated liver levels of PMF metabolites may be directly responsible for their hypolipidemic effects in vivo.

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Date: May 17, 2005 06:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Policosanol and cholesterol control ...

In addition, after 30 days of therapy, 20 and 40 mg/day policosanol significantly ( P < 0.01) reduced low-density lipoprotein– cholesterol (15.9 and 17.0%, respectively) and total cholesterol (12.4 and 12.3%, respectively; P < 0.05), yet increased high-density lipoprotein–cholesterol values by 5% in both groups ( P < 0.05).

Policosanol is a mixture of higher aliphatic primary alcohols purified from sugar cane ( Saccharum officinarum L) 4,5 wax, the main component of which is octacosanol, followed by triacontanol and hexacosanol; other alcohols (Tetracosanol, heptacosanol, nonacosanol, dotriacontanol and Tetratriacontanol) are minor components. The cholesterol-lowering effects of policosanol have been proven in healthy volunteers, 6,7 patients with type II hypercholesterolaemia 8–25 and in dyslipidaemia due to type II diabetes mellitus. 26,27

The hypocholesterolaemic effect of policosanol is associated with inhibition of cholesterol biosynthesis at a step located between acetate consumption and mevalonate production, although inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase has been discarded. 28–30 Policosanol also increases low-density lipoprotein (LDL) receptor-dependent processing in fibroblast cultures, 28 as well as the clearance of [ 125 I]-labelled LDL–cholesterol (LDL-C) administered to rabbits with hypercholesterolaemia induced by a cholesterol-free casein-rich diet. 29

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