Search Term: " deprivaion "
33 matching the search criteria.
The Consequences of Not Getting Enough Sleep
September 14, 2022 04:03 PM
Author: Darrell Miller
Subject: The Consequences of Not Getting Enough Sleep
Most people know they should be getting around eight hours of sleep per night, but according to the National Sleep Foundation, between 50 and 70 million U.S. adults havea sleep disorder*. That means many of us are not getting the quality sleep we need on a nightly basis. But what does that mean for our health? Let’s take a look.
Short-Term Effects of Sleep Deprivation
There are many short-term effects of not getting enough sleep, including:
* Difficulty concentrating or making decisions * Increased forgetfulness * Moodiness or irritability * Slow reflexes * Increased anxiety * Decreased sex drive * Weight gain or weight loss * Heightened senses * Increased susceptibility to colds and flus
Long-Term Effects of Sleep Deprivation
The long-term effects of sleep deprivation are even more concerning. Some of the long-term effects of not getting enough sleep include:
* High blood pressure * Diabetes * Heart disease * Mood disorders such as depression or anxiety * Memory problems * weakened immune system * Increased pain perception Conclusion: As you can see, there are many short-term and long-term effects of not getting enough sleep. If you think you might have a sleep disorder, talk to your doctor about treatment options. In the meantime, practice good sleep hygiene by avoiding caffeine before bedtime, establish a regular sleep schedule, and create a calming bedtime routine. Do your best to get seven to eight hours of quality sleep every night so you can wake up feeling refreshed and ready to take on the day!
Need more sleep try melatonin!
What is Melatonin?
Melatonin is a hormone that helps regulate our sleep-wake cycles. It's produced naturally by our bodies in response to darkness and starts to increase in the evening as we prepare for bed.
How Does Melatonin Work?
Many people take melatonin supplements in an effort to improve their sleep quality. And there is some evidence to suggest that it can be helpful. One small study found that melatonin supplements helped people fall asleep faster than placebo pills did. However, the effects were only temporary, lasting for just three days.
Another study looked at the effects of melatonin on people with insomnia due to jet lag. This research found that melatonin supplements shortened the time it took for participants to fall asleep by about an hour on average.
It's important to note that these studies looked at short-term usage of melatonin supplements. There's not much research available on the long-term effects of taking this supplement.
If you're struggling to get enough sleep, you might be wondering if supplements could help. One popular option is melatonin. But what is it, and does it really work? Melatonin is a hormone that helps regulate our sleep-wake cycles which is produced naturally by our bodies in response to darkness.. Many people take melatonin supplements in an effort to improve their sleep quality and there is some evidence to suggest that it can be helpful such as one small study found that melatonin supplements helped people fall asleep faster than placebo pills did.. however the effects were only temporary lasting three days or another study which looked at the effects of melatonin on people with insomnia due to jet lag and found that it shortened the time it took participants to fall asleep by an hour on average...
Give Melatonin a try and sleep better!
The steep cost of sleep deprivation
January 01, 2018 08:59 AM
Author: Darrell Miller
Subject: The steep cost of sleep deprivation
There is a steep cost to sleep deprivation. People need to get plenty of sleep at night, or they will suffer the consequences. Sleep deprivation does the same thing to your body as physical stress does and even illness. It is something to avoid. If you do not get enough sleep then you are putting yourself at risk of developing some bad diseases. Sleeping is also an important thing for our emotional balance. Fatigue hinders your ability to regulate emotions.
- Besides health issues, sleep is important to maintain a stable mental balance.
- And taking sleeping bills is dangerous to your overall health as bill users have a 35% higher risk for certain cancers.
- Poor or lack of sleep leads to increased risk of car accidents, reduced productivity and obesity.
"Cutting just one hour of sleep a night increases the expression of genes associated with inflammation, immune excitability, diabetes, cancer risk and stress."
Read more: https://www.healthnutnews.com/the-steep-cost-of-sleep-deprivation/
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If you get less than 7 hours of sleep, this is what can happen to your belly fat
July 21, 2017 12:14 PM
Author: Darrell Miller
Subject: If you get less than 7 hours of sleep, this is what can happen to your belly fat
When adult don’t get the recommended amount of sleep (7-8 hours), the body is out of balance, especially with a proper eating schedule. Sleep deprivation can lead to poor nutritional habits (i.e. eating convenience food at any hour of the day). This can lead to heart disease and diabetes. Getting enough sleep allows the body to reset and can help ward off many diseases. There are many techniques, such as hypnosis shown in the video, or limited screen time before bed, to relax and aide in the sleeping process.
- Levels of endocannabinoid 2-arachidonoylglycerol (2-AG), a chemical that makes foods pleasurable, were elevated when the participants were sleep deprived.
- Another revealing study showed that one night of sleep deprivation led to impairments in insulin sensitivity similar to those caused by six months of eating a poor diet.
- Insufficient sleep may also be a contributing factor in the recurrence of breast cancer and more aggressive forms of breast cancer among post-menopausal women
"Even willpower may not be enough to overcome lack of sleep’s not-so-subtle influence on your appetite, as sleep restriction is associated with activation of your endocannabinoid system — the same one activated by marijuana."
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4 ways lack of sleep or sleep deprivation affects the brain
June 13, 2017 07:14 AM
Author: Darrell Miller
Subject: 4 ways lack of sleep or sleep deprivation affects the brain
There are 4 ways that lack of sleep deprivation affects the brain. It can cause severe mood swings among other things. It will impair your overall performance in life. This will affect your personal and work life. Your memory and your thinking process will also be greatly affected. Sleep helps your learning and your memory. It will lead to psychiatric problems. Overall, sleep is an important part of our lives and we need it in order to function.
Read more: 4 ways lack of sleep or sleep deprivation affects the brain
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TAKE THIS and you will sleep almost instantly and wake up refreshed. Amazing!
May 25, 2017 12:14 PM
Author: Darrell Miller
Subject: TAKE THIS and you will sleep almost instantly and wake up refreshed. Amazing!
For those millions of people that have trouble sleeping, there is a natural remedy that is only comprised of three ingredients and can make you fall asleep quickly and safely as it relaxes your body. This recipe contains the natural ingredients of one tablespoon of coconut oil, one eight of a teaspoon of salt, and a quarter teaspoon of raw honey. This mixture is best taken before bedtime and can be taken two different ways. First, you can combine all ingredients and then consume a glass of water. Or, you can consume the honey and oil separately and then consume water with salt. All three ingredients help play a separate role in helping you sleep as they help secrete hormones to hep you sleep and make you wake up feeling better the next day. https://www.youtube.com/watch?v=FKmpLC4Vr5c&rel=0
- Millions of individuals suffer from sleep deprivation, due to insomnia, and other sleep-related issues.
- One purported natural cure for insomnia involves the use honey, sea salt and coconut oil.
- An easily prepared combination of these ingredients acts to lessen the effects of cortisol spikes, which can adversely affect sleep cycles.
"There is a completely natural remedy that will restore your sleep and will help you wake up fresh and in a good mood."
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Zinc supply affects cardiac health
April 26, 2017 06:59 PM
Author: Darrell Miller
Subject: Zinc supply affects cardiac health
The level of zinc in the body can strongly affect the heart muscle. The Chair of Animal Nutrition at TUM put this theory to the test on piglets deprived of zinc for a period of time. They were able to find that zinc deprivation can be linked to oxidative stress which in turn can be linked to many different heart issues. After a few days into the study, it was found that the body could no longer compensate for absent amounts of zinc. As the heart attempted to compensate, other organs were affected. Other studies also concluded similar research.
Read more: Zinc supply affects cardiac health
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CBD and MS: Can Marijuana Treat Multiple Sclerosis?
April 26, 2017 03:59 PM
Author: Darrell Miller
Subject: CBD and MS: Can Marijuana Treat Multiple Sclerosis?
Although cannabis is still illegal on a federal level, more states have been passing laws to make this miracle plant available to those in medical need (and some even recreational). Cannabis has been shown to greatly help people who are suffering with MS by treating some of the symptoms (inflammation, pain, sleep deprivation, and even depression). It has also been noticed to have a preventive factor when it comes to protecting the eyesight of the patient.
- MS affects the central nervous system, the brain, the spinal cord and the optic nerve.
- CBD can stop MS from progressing and induce healing of MS symptoms.
- CBD also helps with inflammation, sleeplessness, and depression. Furthermore it helps with the pain and releases muscle tension.
"As the many benefits of marijuana continue to be discovered across the country, more and more states are deciding to legalize the plant for both recreational and medicinal use. One of the disorders that is considered treatable by medical marijuana is Multiple Sclerosis (MS)."
Read more: http://www.marijuanaresources.com/cbd-and-ms-can-marijuana-treat-multiple-sclerosis/
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How You Can Stop Overeating
March 03, 2017 07:59 AM
Author: Darrell Miller
Subject: How You Can Stop Overeating
Overeating is a major problem in America and the obesity rate is rising. Several things you can do to prevent obesity or lose some pounds is eat healthier for a start. Cut out the processed food and the sugar. Try eating more fruits, vegetables and low cal snacks as well as plenty of water. Track what you are eating and why.
- Overeating is the major cause of the obesity epidemic in America for the last 3 decades.
- Our first inclination is to just starve ourselves. But this ends up backfiring because we go into a deprivation mode. This makes us overeat and in the end, you gain even more weight.
- The single most important action to take to stop overeating is to eat healthier. This means to stop eating processed foods and eating more vegetables, nuts, whole grains and lean meats like chicken or fish.
"The single most important action to take to stop overeating is to eat healthier. This means to stop eating processed foods and eating more vegetables, nuts, whole grains and lean meats like chicken or fish."
This is How the Brain Regulates Your Sleep
February 10, 2017 07:59 AM
Author: Darrell Miller
Subject: This is How the Brain Regulates Your Sleep
The brain regulates your sleep in an interesting way. Sleep is an interesting thing to learn about. It is still a mystery. There has been a lot of speculation as to how the brain induces sleep patters. It's been noted that sleep patterns and things in that arena are related to things like mental illness. Sleep is extremely important to study.
- Scientists have known for a while that an unusual sleep routine or insufficient sleep can lead to mental as well as physical illness. Sleeping disorders are found to be the root cause of many diseases including dementia.
- The recent research conducted by researchers at the Harvard Medical School has discovered that sleep may be regulated in part by brain-based immune proteins.
- Results of the study showed that the inflammasome recruits a sleep-inducing molecule to trigger somnolence following sleep deprivation and exposure to a bacterial toxin. Animals which lack genes for this protective immune complex showed profound sleep aberrations.
"Results of the study showed that the inflammasome recruits a sleep-inducing molecule to trigger somnolence following sleep deprivation and exposure to a bacterial toxin."
Lack of Sleep Could Be Doing This to Your Heart
January 01, 2017 01:59 PM
Author: Darrell Miller
Subject: Lack of Sleep Could Be Doing This to Your Heart
New mothers, college students and emergency room doctors all have something in common: sleep deprivation. But is getting little to no sleep on a regular basis bad for your health? The evidence says yes. According to a recent study, getting less than three hours of sleep within twenty-four hours causes increased strain on the heart, elevated blood pressure, and increased heart rates. Thyroid hormones and cortisol also went up, which can lead to stress and eventually heart disease. It is clear that getting enough sleep is in your best interests in the short- and long-term, along with a healthy lifestyle.
- the occasional all-night without a second-thought about what might happen to our bodies in the process.
- Our friends at Shape Magazine share their findings about lack of sleep's health consequences.
- all routinely need to make it through the day on no or very little sleep. And while no one thinks pulling an all-night is good for your health, there's actual evidence that it hurts your heart.
"Getting less than three hours of sleep during a 24-hour period causes immediate heart problems, according to a new study presented at the annual meeting of the Radio logical Society of North America. Researchers looked at 20 healthy adults."
Enzyme that digests vitamin A also may regulate testosterone levels
December 15, 2016 10:59 AM
Author: Darrell Miller
Subject: Enzyme that digests vitamin A also may regulate testosterone levels
Want to help regulate testosterone in the body? Well a new enzyme was just discovered that helps break down enzymes in the body that regulate and make the most out testosterone. This could be important for testosterone replacement therapy. It is a good breakthrough, it can help those in need.
- A new study suggests that an enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone and prostate growth.
- The findings suggest that the loss of Bco1 significantly affects androgen synthesis and reduces AR signaling, decreasing prostate growth.
- These findings support the hypothesis that androgen deprivation, whether by castration or loss of Bco1, controls cellular proliferation in the mouse prostate.
"The scientists also found evidence that androgen receptor signaling was disrupted in the mice without the Bco1 gene."
Holiday Survival Tips!
December 15, 2016 08:59 AM
Author: Darrell Miller
Subject: Holiday Survival Tips!
Deprivation does not work. The key to healthy eating is an ample and ready supply of the right foods. The right foods contain nutrients such as vitamins, minerals, protein, and nutrients like essential fatty acids (EFAs), carotenoids, and bioflavonoids, which have gotten so much attention in the nutrition research literature.
- If you start to feel a bit stressed, stop for a moment and give thanks for what's right in front of you.
- Follow your regular eating pattern at breakfast and/or lunch.
- It can be difficult enough to find time and energy to focus on our health during the other eleven months of the year. Sticking to our healthy habits in December might seem downright impossible.
"Appreciate the presence of YOU in your life – your breath, your health, your generosity."
Getting a Good Night's Sleep w/o Rx Drugs
December 15, 2016 06:59 AM
Author: Darrell Miller
Subject: Getting a Good Night's Sleep w/o Rx Drugs
High-fiber diet keeps gut microbes from eating the colon's lining, protects against infection, animal study shows
December 02, 2016 04:59 PM
Author: Darrell Miller
Subject: High-fiber diet keeps gut microbes from eating the colon's lining, protects against infection, animal study shows
A high-fiber diet rich in vitamin A may alter gut bacteria in a way that could prevent or reverse food allergies. In their study, the team found that increased levels of these fatty acids work with the body's immune system, preventing dendritic cells - which regulate food allergies - from triggering an allergic response. Vitamin A is also important for dendritic cell regulation.
- When mice were raised germ-free, then given a transplant of human gut microbes, the impact of fiber on their colons could be seen.
- In a new paper in Cell, an international team of researchers show the impact of fiber deprivation on the guts of specially raised mice.
- The findings have implications for understanding not only the role of fiber in a normal diet, but also the potential of using fiber to counter the effects of digestive tract disorders.
"When mice were raised germ-free, then given a transplant of human gut microbes, the impact of fiber on their colons could be seen."
10 superfoods you can include in your daily diet to cut diabetes risk
December 01, 2016 02:59 PM
Author: Darrell Miller
Subject: 10 superfoods you can include in your daily diet to cut diabetes risk
The Health Benefits of Grape Seed Extract
November 14, 2016 10:20 PM
Author: Darrell Miller
Subject: The Health Benefits of Grape Seed Extract
Grape seed extract is most commonly a waste product produced by the grape juice and winery industry. This is because grape seed extract doesn't go into finished drinks. Grape seed contains a wide variety of health-enhancing ingredients like protein, carbohydrates and lipids (healthy fats).
A study done on healthy volunteers found that grape seed considerably increased the levels of antioxidants in the blood. So, another one of the benefits of grape seed is it helps boosts the immune system to fight against harmful compounds which may reduce the risk of chronic diseases including breast, stomach, colon, prostate and lung cancer.
Vascular Endothelial Health
Grape seed extracts have been tied to the prevention of cardiovascular diseases partly due to the long association of grape wines with low prevalence of heart diseases among the French. Besides, there is a growing literature devoted to the health potential of grape seed concerning their positive effects on vascular endothelial growth factor, a type of protein that signals the development of new healthy blood vessels and improves the circulation of oxygen to tissues that suffer oxygen deprivation.
High Blood Pressure
Due to its antioxidant activity that may protect the blood vessels, grape seed extract could theoretically benefit people with high blood pressure. The UMMC points out that study in animals indicate that it's useful for this purpose. However, there are no human studies that have looked at grape seed extract's effect on hypertension.
The Memorial Sloan-Kettering Cancer Center states that one study suggests that grape seed, when taken with chromium, may lower "bad" blood cholesterol. The UMMC describes grape seed extract's effects on blood cholesterol as "promising"; however, more research is needed to see if grape seed is beneficial for this purpose.
In one study, patients with chronic inflammation of the pancreas (pancreatitis), grape seed extract showed promise. It appeared to significantly reduce the frequency and intensity of symptoms such as abdominal pain and nausea. This occurred even after conventional medications failed to help. These results are very preliminary and further studies will be needed to confirm these findings.
Black Cohosh : Herbal Remedy For Menopause
September 06, 2016 03:38 PM
Author: Darrell Miller
Subject: Black Cohosh : Herbal Remedy For Menopause
Black Cohosh is a herb native to Eastern North America which has been popular in relieving the symptoms of menopause. The root of the herb has proven to be a effective remedy for menstrual cramps,vaginal dryness, premenstrual syndrome (PMS) and period pains. Studies have shown it to be effcetive against menopause symptoms like irritability, mood wings and sleep deprivations.
Black Cohosh has been considered an effective safe alternative for estrogen replacement therapy (ERT) for someone who don't want to take prescription estrogen.
The anti inflammatory property has also made it a popular against inflammation caused by arthritis and neuralgia. Dosage should be taken properly or it may cause side effects like upset stomach.
Note: Black cohosh contains property similar to that of estrogen and since effect of estrogen varies according to person and age, hence its results may vary person to person.
If you are looking for PMS and menopausal relief, look no further, give black cohosh a try!
Can Adrenal Extract Support Adrenal Function?
April 09, 2014 11:47 PM
Author: Darrell Miller
Subject: Can Adrenal Extract Support Adrenal Function?
Effects low adrenal to body
As the adrenal organs affect all body forms, a diminishing in their capacity might be seen practically anywhere. The standard first side effect of LAF is regularly weariness. Individuals experiencing issues getting up in the morning or have spurts of exhaustion at diverse times of the day. Frequently, the following side effect is an inclination of shortcoming, discombobulating or expanded heart rate when climbing from a sitting position to standing. In the event that the issue is not tended to, additional manifestations take after:
Cause of low adrenal level
With adrenal weariness, your body does not process enough cortisol to keep glucose levels consistent as you experience your normal 8-10 hour when we rest. As glucose levels begin to drop throughout the center of the night, ordinarily your adrenal organs discharge cortisol to help push glucose levels move down. These hormones are Central Nervous System stimulants and will wake you up. This is the reason you may appear to get up, wide up and about.
It is critical to take a gander at all the elements that help adrenal weakness and hyperactive action. A sleep deprivation prescription will never alter the center issue in this case. The very situation recently portrayed to you is exceptionally normal. There are numerous variables that must be viewed as including circadian musicality of cortisol discharge, lifestyle components, passionate anxiety, and sustenance sensitivities, in addition to everything else. There is nobody size fits all medication for this syndrome however you can have triumph and overcome you’re a sleeping disorder in the event that you discover a specialist who takes a thorough, all common, huge picture methodology, to this advanced disease called Adrenal Stress Syndrome .
Types of adrenal stress syndrome
Temperament swings: When the cerebrum isn't getting enough sugar, it doesn't work appropriately. A way the cerebrum builds the breakdown fat into sugar is by creating a solid feeling, for example, indignation or great misery. An individual typically feels better a short time later, in the same way that they will be less passionate in the wake of consuming.
Desires of desserts: As the adrenal organs tell the pancreas what amount of insulin is required to process in a dinner, when the adrenal organs are not working accurately, they don't correctly correspond with the pancreas, so a lot of insulin has a tendency to sent by the pancreas for anything consumed subsequently glucose levels drop rapidly after supper; this causes the starch longings.
Mental burdens: Anything that causes mental or enthusiastic misery will fortify the adrenal organs to transform substances to help with the impacts of the anxiety (epinephrine, norepinephrine, and serotonin). Delayed mental anxiety, for example, needing to meet a due date, last test of the years, being in an oppressive relationship, and so forth will result in the adrenal organs to need to capacity without enough breaks.
5-HTP and how it can help promote natural sleep patterns.
November 27, 2013 07:47 AM
Author: Darrell Miller
Subject: 5-HTP and how it can help promote natural sleep patterns.
What is 5-hydroxytryptophan (5-HTP)?
5-hydroxytryptophan (5-HTP) is a substance derived from Griffonia simplicifolia’s seed pods. In the human body, 5-hydroxytryptophan is an immediate nutrient precursor to neurotransmitter serotonin. This implies that 5-HTP directly converts into serotonin in human brain. Serotonin plays very many essential functions such as; a role in appetite, learning, sleep, memory, temperature regulation, cardiovascular function, endocrine regulation, sexual behavior, mood and muscle contraction.
The production of serotonin declines with age, however it’s also important to note that, at any age serotonin production can be further compromised by stress. Low serotonin levels are commonly manifested by insomnia, depressed mood and anxiety.
It is known that insomnia is an age-related condition. Sleep disorders are associated with very significant psychological, medical and social disturbances. Sleep deprivation can cause depression, stress and anxiety, it can also lead to fatigue, impairment of memory, immune function and mood. Nutritional supplements that contain 5-HTP, choline, melatonin and valerian root helps one to get a good sleep hence alleviating these problems. Recent research has indicated that increased serotonin levels can assist individuals suffering from chronic sleep disturbances restore healthy sleep patterns.
Pathways of serotonin
One of the metabolic pathways of serotonin leads to melatonin a hormone widely acknowledged for being responsible for the sleep-wake cycle. By increasing serotonin’s level with 5-HTP, you are also increasing the melatonin levels. Melatonin is also known to improve the immune function and assist improve immunodepressions that are stress-induced.
Valerian root is a Eurasian herb that has been for long known for enhancing sleep. Valerian helps one to fall asleep and also improves the quality of sleep thus allowing one to wake up feeling refreshed. A study showed that people who used valerian were more active and alert .
Choline is a nutrient precursor to neurotransmitter acetylcholine, that assists to protect your sound sleep so that you are not woken up by every little murmur or cleak.Supplementing the diet with these natural substances will assist eradicate or diminish sleep disturbances and also assist reestablish healthy sleep patterns.
Can L-Carnosine Be Used As An Anti-Aging Vitamins?
April 18, 2012 07:31 AM
Author: Darrell Miller
Subject: Can L-Carnosine Be Used As An Anti-Aging Vitamins?
Carnosine And Your Health
Carnosine has gained widespread popularity as an anti-aging compound despite some skeptical voices in the scientific community. Many studies lend credence to its value for treating the signs of aging and its antioxidant properties are well researched. Carnosine is also widely used as a supplement to prevent complications from diabetes such as nerve and kidney damage. This article will discuss the details of what it is, what it seems to do in the body and how it may be able to help people restore a more youthful state of health.
Discovered in Russia more than a century ago, Carnosine is an amino acid and is found primarily in muscle, skeletal and nervous tissue (including the brain). As such the primary dietary sources are animal products such as fish, poultry and red meat. It is common for vegetarians to become deficient in it, making them ideal users of carnosine supplements.
There is a gradual decline in carnosine levels as we age, which lends credence to the claims of its anti-aging properties. The most clearly established property of carnosine is its ability to act as an anti-glycation agent. Glycation is a process the body goes through to release energy from sugar but which ends up producing harmful substances. Carnosine can neutralize some of these already formed substances and also prevent the process from forming new ones. Some researchers believe glycation may be the key behind the benefits of caloric restriction, making carnosine the long awaited magic pill that can mimic its effect as a longevity treatment without the deprivation of restricting food intake.
In addition to carnosine's anti-glycation effect, it also has antioxidant properties. The oxidation process which the body goes through naturally produces the well known "free radicals" which slowly damage the cells and are thought to play an important role in the aging process. Carnosine can neutralize this protecting the cells. This also has a beneficial effect at keeping the telomeres from shortening, which is thought to be the main cause of the aging process. Telomeres are the buffers at the ends of DNA code that protect the code from being corrupted, so when the telomeres become shorter there is less protection and a greater chance of things going wrong. This makes carnosine's protective benefits of great importance in the fight against aging.
Carnosine Protects The Cells From Damage Like Radiation
Studies show that carnosine can protect the cells from radiation damage, which is particularly useful for cancer patients who have to undergo radiological treatment. It also promotes the healing of wounds and protects cell membranes. Some studies demonstrate that it can literaly repair old cells and make them younger. As it binds easily to toxic metals, turning them into powerful antioxidants, it is very effective at protecting the body from their harmful impact.
Some of the most promising uses of carnosine are for the treatment and prevention of Alzheimer, the signs of aging in the skin, cataract, nerve and kidney damage and heart disease. The recommendation for use as a supplement is 500 miligrams, though the body can deal safely with much larger doses. Give Carnosine a try today and experience the difference yourself.
How Does Passion Flower Help Me Relax ?
April 07, 2011 01:39 PM
Author: Darrell Miller
Subject: How Does Passion Flower Help Me Relax ?
Passion flower refers to a group of flowering plants that belongs to the genus Passiflora, comprising of up to 500 species. The commonly known plant species of Passiflora are climbing vines with a woody stem system although there are a few herbaceous shrubs. They are found across the globe with the exception of arctic and sub-Saharan regions and easily recognizable by their unique flower structure which often contains prominent styles and stamens. Passiflora incarnata, or more commonly known as Maypop in the vernacular, has a long association with folk medicine of American Indians, who use various parts of the plant as a relaxant.
Different species of Passiflora are called different names, but the trivial name passion flower pertains to the corona that resembles the crown of thorns worn by Jesus. Moreover, the Christians have ascribed many symbolisms for the intricate parts of the flower. For example, the ovary is believed to represent the Holy Grail. Early European settlers in the Americas discovered the calming effects of teas made from Passiflora species through the Indians, and popularized its use against anxiety soon after in Europe.
Produces Tranquilizing Effects
Several studies have investigated the effects of passion flower on human health, with a few comparing it to the drug exazepam. Its mechanism of action is still under scrutiny, but scientists are convinced that its sedative effects are very similar to the herbs Valeriana officinalis and Piper methysticum. More often than not, it is used in combination with these two herbs. As a mild relaxant with a slow onset of action, Passiflora incarnata, or Maypop, have been documented to benefit individuals suffering from irritability, insomnia, and agitation. In conjunction with a drug called clonidine, it also appears to relieve muscle tremors.
Increases Inhibitory Brain Chemicals
It has long been postulated that passion flower works on the principle of raising the levels of inhibitory neurotransmitters, such as gamma-aminobutryric acid, or GABA. Glutamic acid, the biological precursor of gamma-aminobutyric acid, has been linked to neuronal excitotoxicity that leads to many known diseases of the nervous system. By aiding the metabolic pathway responsible for converting glutamate into gamma-aminobutyric acid, passion flower not only increases the amounts of the chief inhibitory brain chemicals in the human brain and the rest of the central nervous system, but also lowers the levels of excitatory neurotransmitters. This results in a drop in neuronal activities and a reduced risk of excitotoxicity, which translated into a more relaxed feeling.
Alleviates Physical Fatigue
Passion flower is known to counter the harmful effects of stress. In addition to alleviating psychiatric symptoms of anxiety, Passiflora incarnata has also been tied to the treatment of muscle weakness characteristic of fibromyalgia. It is one of the herbal nervines used in combination with other herbal adaptogens in combating physical fatigue due to long hours at work and the consequent sleep deprivation. Fortunately, passion flower is generally considered safe and nontoxic, with dosages equivalent to food proportions in general.
Passion flower can be taken with valerian and skull cap to help calm the mind and body when under intense stress. Give it a try and See for yourself!
Can L-Arginine Really Help with Circulation Blood Flow?
February 05, 2011 01:43 PM
Author: Darrell Miller
Subject: Can L-Arginine Really Help with Circulation Blood Flow?
The incorporation of nutrients from our diet to the parts of the human body is taken care of by the network of blood vessels that make up the circulatory system, including the distribution of oxygen. Blood flow in effect largely contributes to the effective utilization of bioactive substances from digested foods. The muscles that line the inner walls of blood vessels are responsible for healthy circulation with the aid of a substance that is catalyzed from L-arginine.
Arteries, capillaries, and veins are the three primary members of the vascular highway that forms the systematic circulation. The arteries from the heart branch out in smaller vascular tubes called capillaries, which are connected to the system of veins leading back to the heart. Blood continuously flows inside this complex loop of tubes and brings nutrition to the tissues at the end of capillaries.
Endothelium and Smooth Muscle Cells
Circulation is a vascular function regulated by the smooth muscle cells within the blood vessel walls that promote streamline flow to avoid turbulence. In a lifetime the flow may result in chaos, depending on the health of blood vessels. A special class of tissues exposed to the blood plasma known as endothelium stimulates the smooth muscle cells that make up most of the systematic circulation to perform its function. However, factors associated with aging interfere with the proper functioning of both the smooth muscle cells and the endothelium.
The human body possesses a gene responsible for the encoding of a group of enzymes that aid healthy blood flow in the circulatory system. This gene identified as Endothelial Nitric Oxide Synthase (NOS), as the name suggests, has something to do with the endothelium and the chemical compound nitric oxide. While chronic expression of nitric oxide in the body may lead to inflammatory diseases, this gas actually serves a focal role in preventing damage to all tissues in the human body resulting from the deprivation of blood supply.
Nitric Oxide and L-Arginine
How? Nitric oxide is produced at the right amounts by all mammals for use as a signaling agent at the cellular level. In the circulatory system, nitric oxide is known to display vasodilator properties, that is, it brings about the relaxation of smooth muscle cells that line the blood vessel walls. Vasodilation is central to circulation and blood flow inasmuch as the widening of vascular walls leads to the flow of blood. Since nitric oxide must be manufactured at healthy levels, it is regulated by Endothelial NOS.
However, its production depends on the availability of Arginine in the human body. The amino acid L-arginine is not synthesized at sufficient amounts at all times, and thus it must be derived from our diet. No one can really tell what conditions govern the biosynthesis of L-arginine, and for individuals who have poor nutrition, levels of L-arginine are significantly low. This is the reason why medical professionals advocate the use of L-arginine to counter vascular diseases. Supplementation of L-arginine has in fact been associated to healthy circulation.
NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE
December 10, 2009 04:23 PM
Author: Darrell Miller
Subject: NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE
NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE™
NADH is the biologically-active form of vitamin B-3 (niacin), and is involved in a wide range of functions throughout the body. An easier way to understand it, is to think of NADH as a biological spark plug that makes it possible for us to become and remain energetic, active, and functioning at our best. Remove the “spark” and some of the most basic human functions will inevitably suffer. This is not speculation. It is the result of decades of scientific investigation that has examined the link between nutrition and chronic conditions; notably those related to cellular life cycles and apoptosis, excessive fatigue, enzyme decline, free radical expansion, cognitive disparity, intracellular balance, normalized aging, and many more important aspects of human health.*
Based on a wealth of ongoing studies, we have a great understanding of the benefits of NADH. Not only is it an effective source of cellular energy, it is also one the body’s versatile electron donors—the molecule most frequently degraded during oxidation. Because of these characteristics NADH is, however, also very unstable with regard to light and oxygen, which leads to a very rapid loss of overall effectiveness. Additionally, poor lifestyle choices, such as the use of tobacco, excessive consumption of alcohol, drugs, and prescription medications, sleep deprivation, genetically-engineered foods, and a host of others can all inhibit the activity of NADH within the body. Hope is not lost, however.
NOW® NADH contains a patented form of NADH from Panmol® - the first natural stabilized, stomach acidresistant form of this unique vitamin B3 supplement. Panmol® uses a patented process to naturally preserve its effectiveness. The end result is a highly stable, and bioavailable NADH which can easily withstand the harsh, acidic environment of the stomach and digestive tract; a breakthrough in the battle against many of todays’ most chronic conditions. NOW® NADH is available in both 10 and 20 mg potencies. Both varieties have been further enhanced with 200 mg of Bioenergy RIBOSE™ to support its cellular energy support properties.*
Who Stands to Benefit from NADH
With a proper supply of amino acids and/or B3 vitamins (niacin) the human body is, in fact, capable of producing a limited reserve of NADH. Under chronic strain however, the body’s need for NADH increases. As we age, the body’s ability to manufacture NADH becomes increasingly limited. With this in mind, the following groups stand to benefit the most from incorporating NOW® NADH into their supplement regimen.
• Those who work in stressful, cognitively-demanding professions
• Individuals who frequently struggle with fatigue
• People who have difficultly focusing on routine tasks
• Older and elderly individuals
• Those who want to maintain a high level of mental alertness
• Professionals who travel extensively for business
• Those who experience jet-lag after long flights
October 01, 2009 11:57 AM
Author: Darrell Miller
Subject: Ginkgo Biloba
In the past decade, ginkgo has received much attention. It has been revered throughout China and other areas of Asia for thousands of years. However, its popularity increased in Western countries. An increase in sales can be attributed to interest in the benefits of ginkgo on conditions that are associated with aging like Alzheimer’s, memory loss, dementia, and circulatory disorders. Often, gingko is used to increase the blood flow to the brain, which improves memory problems like Alzheimer’s, to prevent strokes, and to increase blood circulation through vasodialation. The improved circulation is also thought to improve ear conditions, help blood flow to the retina, aid in preventing muscular degeneration, reduce frequency of asthma attacks, and help transplant recipients avoid rejection.
The ability of ginkgo to boost brain function has been studied extensively. Most importantly, ginkgo increases oxygen supply to brain cells, as the brain is the body’s most sensitive organ to oxygen deprivation. Additionally, ginkgo has been used to improve electrical transmission in nerves and supply more oxygen and nutrients to brain cells. The effect that ginkgo has on the brain and circulatory system disorders seems to be extremely promising for a variety of conditions. Ginkgo has also been found to be effective in treating migraine headaches. In one study that took place in 1975, ginkgo extract was given to individuals who were suffering from migraines. Results concluded that eighty percent of the patients showed improvement or were cured of the condition.
Ginkgo extract has also helped dementia that results from poor blood flow to the brain. Senile dementia is often recognized by depression, unusual fatigue, and memory problems. Ginkgo has the ability to help improve circulation to the brain tissue, which in turn improves brain function.
Blood platelet aggregation, or clotting, can cause serious problems in the body. Among these are strokes, heart attacks, and coronary thrombosis. It has been found that ginkgo can reduce the tendency for platelets to stick together and prevent them from forming clots in the arteries and veins.
The brain and nervous system are extremely sensitive to free-radical damage because of the high percentage of unsaturated fatty acids. It has been found that ginkgo’s antioxidant activity is particularly powerful in these areas, along with the eye and retina. This is extremely helpful in conditions like retinopathy, cataracts and macular degeneration. The central nervous system possesses fat lipids in the cell membranes that are typically attracted by free radicals. Ginkgo can help protect these cell membranes and prevent condition which can occur in the brain and nervous system that are often associated with aging, like memory loss.
The leaves of the ginkgo plant are used to provide adaptogen, alterative, antioxidant, antiseptic, and stimulant properties. Primarily, ginkgo is extremely helpful in treating ADHD, Alzheimer’s disease, lack of attention span, blood clots, cardiovascular disorders, poor circulation, dementia, dizziness, edema, impotence, inflammation, ischemia, memory loss, lack of mental clarity, multiple sclerosis, muscular degeneration, PMS, Raynaud’s disease, senility, stress, stroke, and tinnitus.
Additionally, this herb is very helpful in dealing with allergies, angina, anxiety, arthritis, asthma, cancer, carpal tunnel syndrome, coughs, depression, lack of equilibrium, eye problems, hearing problems, hemorrhoids, lung disorders, migraines, mood swings, toxic shock syndrome, transplant rejection, varicose veins, vascular problems, and vertigo.
April 05, 2009 01:40 PM
Author: Darrell Miller
Subject: Attentive Child
Attention deficit hyperactivity disorder (ADHD) is the newest name that has been given to a group of disorders of the central nervous system. With the long list of names this disorder has been given over the years, it is often confusing as to which criteria are for a diagnosis of ADHD or ADD. It is estimated that between 3 and 5 percent of children in the United States have ADHD, meaning that at least one child in a classroom of twenty-five to thirty children will have ADHD. There are three times as many boys diagnosed with ADHD, but the condition is increasingly being diagnosed in girls as well.
Although ADHD was primarily thought of as a childhood disorder, it can be found in adults as well. Experts have estimated that as many as 8 million adults may be affected, but 80 percent of them do not realize it. Some studies show that there is significant decline in ADHD symptoms as a person ages, while others estimate that between 30 and 70 percent of children with ADHD will carry some symptoms into adulthood. ADHD is a more complex disorder in adults, but it manifests itself into a problem with self-regulation. Without this self-control, an adult’s ability to do tasks is impaired. This condition can lead to marital conflicts, substance abuse, and financial problems. Infidelity is common because ADHD adults easily become bored with things, including spouses.
Factors that have been linked to the development of ADHD include heredity, anxiety, allergies, smoking during pregnancy, hyperinsulinemia, oxygen deprivation at birth, environmental stress or pollutants, artificial food additives, injury, infection, lead poisoning, and prenatal trauma. More emphasis has been placed on the role of diet in ADHD in recent years. Many people with these conditions react to certain preservatives, dyes, and salicylates in foods. These problems can cause the balance of chemistry in the brain to be thrown off, which produces undesirable changes in behavior. A low-protein diet may also be a contributing factor. Although a hotly debated topic for decades, studies have definitely shown that food additives do play a major role in hyperactivity.
Many researchers feel that ADHD is being over-diagnosed nowadays. It is difficult to accurately diagnose this condition because many of the symptoms appear in the normal, healthy children at many times during childhood. In fact, more than 60 percent of parents suspect that their child has ADHD at some point in their upbringing. What may merely be creativity or a high energy level can be diagnosed as ADHD. A diagnosis of ADHD should be made by a team of specialists who are experts in the disorder and it is wise to get a second opinion.
One should considered nutritional deficiencies and dietary measures for treating ADHD. The following nutrients are recommended: calcium, magnesium, GABA, a multivitamin and mineral complex, Omega-3 fish oil, Pycnogenol, Quercetin, SAMe, acetylcholine, DMAE, l-cysteine, phosphatidyl serine, vitamin C with bioflavonoids, and zinc. Additionally, the following herbs may be beneficial: ginkgo biloba, ginseng, mullein oil, valerian root, catnip, chamomile, gotu kola, hops, kava kava, lemon balm, licorice, lobelia, oats, passionflower, skullcap, St. John’s wort, thyme, and wood betony.
Creating a nutritionally sound diet for children and adults can go a long way to controlling ADHD and ADD in general. Reducing sugar intake and adding good quality food that hasn’t been over processed which removes the needed vitamins, minerals and phytonutrients we all need to live healthy lives. The above vitamins, minerals and herbs are suggested to be helpful for those suffering as well as those who aren’t, but always consult your health care provider before adding dietary supplements to ones diet while on prescription drugs. Quality vitamins can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins, minerals, and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
Green Coffee Bean Extract
October 22, 2008 04:59 PM
Author: Darrell Miller
Subject: Green Coffee Bean Extract
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs.
The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition.
However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here.
The Free Radical Theory of Aging
Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them.
Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging.
Free radicals are generated in the body in four different ways:
1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher.
2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes.
3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting.
4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products.
In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body.
So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell.
Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron.
Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals.
It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol.
The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level.
Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging.
A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life.
There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
Vitanet ®, LLC
What does it do?
May 29, 2008 12:35 PM
Author: Darrell Miller
Subject: What does it do?
Deer antler velvet is also being promoted as a stamina enhancer in those who use it regularly. It is being promoted to have tonic properties. This means it can help the body adapt to certain stressors such as:
* Heat * Cold * Exertion * Trauma * Sleep deprivation * Toxic exposure * Radiation * Infection * Psychological stress
Adaptogens such as deer antler velvet generally do not have negative side effects. They are effective in treating many illnesses and in helping the human body return to a more balanced existence. By helping to build the immune system, deer antler velvet can aid in the prevention of illness, disease and infection.
Modern lab studies are revealing that deer antler velvet contains many nutrients that aid in more than building the immune system. They also help the body to repair tissues and perform other cellular activities that contribute to vitality and higher energy levels.
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
May 18, 2007 01:06 PM
Author: Darrell Miller
Subject: The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
The Awesome Foursome: Coenzyme Q10, L-Carnitine,
The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.
Energy Recycling through the Electron Transport Chain
Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.
Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.
In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.
What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.
Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.
Transporting the Cellular Energy Fuel
Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.
Rebuilding the Cellular Energy Pool
As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.
When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.
Ribose is the only compound used by the body to refill this energy pool. Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency. Ribose is made naturally in the cells from glucose. In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis. So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.
Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy. Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days. But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose. Conditions like ischemic heart disease or congestive heart failure fall into this category. In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.
Switching on the Energy Enzymes
Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism. Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work. Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.
Magnesium deficiency reduces the activity of important enzymes used in energy metabolism. Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function. Small changes in magnesium levels can have a substantial effect on heart and blood vessel function. While magnesium is found in most foods - particularly vegetables - deficiencies are increasing. Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.
Supporting the Links in The Energy Cycle Chain – the Synergy
Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.
The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.
The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.
Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.
These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.
The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.
L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.
Protect the Heart with D-Ribose, Coenzyme Q10, L-Carnitine, and Magnesium at Vitanet ®, LLC
D-Ribose supplied by Bioenergy Life Science
April 19, 2007 02:44 PM
Author: Darrell Miller
Subject: D-Ribose supplied by Bioenergy Life Science
A UNIQUE SUGAR MAY BE KEY TO ENERGIZING THE FAILING HEART Bioenergy Life Science's D-ribose offers promising options for energy-deprived hearts
MINNEAPOLIS, MN, APRIL 18, 2007-Following the recent publication in the New England Journal of Medicine that the failing heart is an "engine out of fuel" (N ENGL J MED 356;11, March 15, 2007), Bioenergy Life Science reports that D-ribose, a simple, five-carbon sugar, is a plausible option for addressing the nation's heart disease epidemic.
"When heart failure develops, many factors are involved, but energy deprivation is among the most important," said John St. Cyr, MD, PhD, the medical director of Bioenergy Life Science. "We've learned recently that patients with heart disease may have a deficient supply of high energy compounds. Past studies have demonstrated that D-ribose supplementation enhances the return of ATP levels with an associated improvement in diastolic function."
D-Ribose, unlike glucose, is a five-carbon sugar important for DNA, RNA, and most importantly, ATP, the "energy currency" of the cells. ATP is crucial in maintaining the integrity and function of every cell, which is necessary for day- to-day health. Ribose is one of the essential components of the ATP molecule.
D-Ribose, as a supplement, has repeatedly shown to improve functional capacity, quality of life, and everyday activities for patients afflicted with congestive heart failure.
Dr. Neubauer's article, "The Failing Heart - An Engine Out of Fuel," calls attention to the important underlying metabolic problem in patients with heart failure. "D-ribose could aid in this metabolic deficiency," said Dr. St. Cyr. "The number of heart failure patients continues to grow every year. By replenishing ATP to an energy-deficient heart we can significantly improve a patient's quality of life."
December 30, 2005 08:53 AM
Author: Darrell Miller
Subject: Essential electrolytes
Every human being is at the mercy of their diet to provide them with a solid foundation of nutrients. This is especially true in the case of endurance athletes, bodybuilders and other adrenaline-seeking competitors. During intense physical training, the body calls upon its reserve of electrolytes such as potassium, magnesium, calcium and sodium to provide the spark needed for increased respiration, muscle contractions, nerve impulses and countless other functions.
A well-stocked cellular arsenal of these nutrients can ultimately lead to greater levels of sustained endurance, muscular strength and mental clarity. Deprivation, on the other hand, is an invitation for disaster. When the body is pushed to extremes, but unable to locate what it needs, it becomes prone to fatigue, cramping, nausea and headaches. Not to mention, last place. Products such as Carbo Gain and ZMA can provide a solid base of nutrients. (See reverse for detailed specifi cations).
Common Sense Guidelines for Avoiding the Flu and Colds
July 28, 2005 02:07 PM
Author: Darrell Miller
Subject: Common Sense Guidelines for Avoiding the Flu and Colds
Common Sense Guidelines for Avoiding the Flu and Colds
1. Eat a healthy diet. The most important way to prevent being infected is through a proper diet. Raw vegetables, fruits, sprouts, nuts, and seeds should be eaten in abundance. Fresh fruit juices such as apple and grape can help the body flush out toxins. Do not overeat. Avoid sugar, soft drinks, white flour products, chocolate, fried foods, alcohol and tobacco.
2. Exercise for health. Exercise at least three times per week to help strengthen the immune system. Regular exercise is known to help enhance the body’s resistance to disease. Exercise can improve the white blood cell count in the body, which fights germs. It stimulates the lymphatic flow and blood circulation, which allows for the blood flow to increase to the brain and all areas of the body. It can help release hormones that actually help you to feel good. Exercise can help relieve anxiety and stress in the body. It can help increase energy and an overall sense of well being.
3. Get plenty of rest. A good night’s sleep helps the immune system fight off illness. This keeps your immune cells powered up, according to research done at the San Diego Veterans Affairs Medical Center. In the study, 42 healthy volunteers were allowed only four hours of shut-eye overnight, which resulted in 30 percent drop in natural killer cells (key players in the battle against viral infections). Sleep deprivation also decreased immune cells, such as T-lymphocytes.3
4. Wash hands regularly. Viruses are easily transmitted during casual contact like shaking hands or touching a doorknob. Wash hands after coming into contact with someone who is ill. Keep hands away from face and mouth.
5. Use paper cups in the bathroom. Viruses can often spread through the family. Using small, disposable paper cups in the bathroom may stop some of the transmission. Toothbrushes should also be replaced regularly to avoid recontamination.
6. Wash towels and linens often. If someone in the family becomes ill, wash towels daily. Hot water should be used in washing to kill the viruses involved.
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Increased Brain Power and Memory with Ginkgo
June 25, 2005 11:23 AM
Author: Darrell Miller
Subject: Increased Brain Power and Memory with Ginkgo
Increased Brain Power and Memory with Ginkgo
Ginkgo’s ability to enhance cognitive function is becoming common knowledge. Boosting the capability of the brain to record information, communicate ideas or recall concepts can all be enhanced by taking ginkgo biloba therapeutically. Evidently, providing a better oxygen supply to brain cells is ginkgo’s primary neural action. The brain is the body’s most sensitive organ to oxygen deprivation. Today, more than ever, the effects of smoking, alcohol and stress in general can diminish brain function and compromise mental alertness. Ginkgo has demonstrated over and over that it can make a significant difference in memory retrieval, fact retention and problem solving.
One of the most impressive aspects of ginkgo is its ability to stimulate circulation and oxygen flow to neural tissue, there by improving cognitive functions and memory. In test cases when ginkgo has been administered, an increase in cerebro-circulation has been noted in both healthy or diseased brain tissue. What makes this finding particularly relevant is that other circulatory enhancers, whether natural or synthetic do not usually possess this capability.
In addition, ginkgo increases oxygen transport at the blood-brain barrier site, while inhibiting the permeability of toxins into brain tissue. As well as boosting blood supply to the brain, ginkgo has demonstrated the ability to increase the rate at which information is transmitted at the nerve cell level.2
In a double-blind study, one group of healthy young women received ginkgo extract, and the other was given a placebo. A memory test was administered and the reaction time in those women who had taken the ginkgo improved significantly. These findings corresponded with EEG tracings which showed increased brain wave activity.3
Short-term memory and basic learning rates can be statistically improved by using ginkgo. Ginkgo’s ability to enhance memory may also be helpful for epileptics who take anticonvulsants. Typically, an anticonvulsant can impair memory function, making it difficult to retrieve names or numbers from memory banks. In addition, although research is lacking, because ginkgo stimulates brain function, it may help to inhibit improper discharging of electrical impulses which is the primary cause of seizures in epileptics. Ginkgo is rapidly gaining an impressive reputation as a brain enhancer. It has demonstrated its capability to improve memory, mental efficiency and the ability to concentrate. It has also been shown to reduce anxiety, headaches, tension, vertigo, and age-related cerebral disorders. Anyone who has suffered a stroke should look into the possible benefits of ginkgo to amplify mental function and clarity.
Considerable research on ginkgo conducted in Eu rope has confirmed that ginkgo does indeed facilitate better arterial circulation as well as improve electrical transmission in the nerves. The latter function also contributes to improved oxygenation and nutrition to the brain.4 Ginkgo is now accepted as a brain booster which improves memory, mental efficiency, cognitive function, communication, orientation and the ability to concentrate. Recently, the notion of using ginkgo for learning disorders has received some attention. Forthcoming research on the subject will help to clarify its potential for treating such conditions.
GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....
June 21, 2005 05:25 PM
Author: Darrell Miller
Subject: GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....
GPC (GlyceroPhosphoCholine): Versatile Life Support Nutrient
Parris Kidd, Ph.D.
GPC - Marked Benefits to the Brain GPC Supports Normal Brain Function GPC Works Through Multiple Mechanisms Dosing, Safety, Tolerability, Compatibility GPC: Nutrient for All Ages
GPC or GlyceroPhosphoCholine (pronounced gli-sero-fos-fo-ko-lean) is a nutrient with many different roles in human health. It reaches extremely high concentrations within our cells, and its abundance in mother's milk suggests it is crucial to life processes. Clinically, GPC has been most intensively researched for its brain benefits. Biologically, it has great importance for the skeletal "voluntary" muscles, the autonomic nervous system, kidneys, liver, and reproductive organs. GPC goes beyond being a brain nutrient; it is a nutrient for vitality and long life.
Marked Benefits to the Brain
As a dietary supplement, GPC's brain benefits are unique. It boosts mental performance in healthy young people, as shown by three double-blind trials. In trials on middle aged subjects, GPC improved several physiologic measures of mental performance: reaction time, visual evoked potential, and EEG delta slow waves. In the elderly, GPC improves mental performance and provides noticeable revitalisation. In 11 human trials with 1,799 patients, memory, attention, and other cognitive measures improved. So did mood (including irritability and emotional lability), and patients often developed renewed interest in relatives and friends. GPC was well tolerated, and generated no bad drug interactions. A large trial on elderly subjects with memory challenges published in 2003 concluded GPC had significant benefits for these individuals.
GPC Supports Normal Brain Function
Circulatory deprivation or surgery can challenge healthy brain function. GPC can speed recovery and support improved quality of life. In four trials with GPC on 2,804 subjects who experienced difficulties under these circumstances, up to 95% showed good or excellent improvement. GPC consistently improved space-time orientation, degree of consciousness, language, motor capacity, and overall quality of life. The investigators concluded GPC offered marked benefits, with an excellent benefit-to-risk profile. Up to half of patients who survive bypass surgery experience problems with memory and other mental performance. A double-blind trial conducted with bypass survivors for six months determined that the GPC group had no remaining memory deterioration, while the placebo group failed to improve.
GPC Works Through Multiple Mechanisms
GPC supports human health through a variety of mechanisms:
1. It helps keep choline and acetylcholine available to the tissues. Choline is an essential nutrient and GPC appears to be the body's main choline reservoir. GPC in mother's milk represents the baby's main source of dietary choline. Acetylcholine (ACh) is an important substance employed extensively throughout the body. ACh is a major brain transmitter; the motor nerves use ACh to drive the skeletal ("voluntary") muscles; the autonomic nervous system uses it to pace all the organs. ACh is also central to mental and physical endurance, and mind-body coordination.
2. GPC is a major cell-level protectant, not as another antioxidant but in pivotal roles of osmotic pressure regulator and metabolic antitoxin. GPC for osmotic regulation can reach very high concentrations in the kidney, bladder, liver, brain, and other organs. As metabolic protectant, GPC shields proteins against urea buildup.
3. GPC is a major reservoir for cell membrane omega-3 phospholipids. These substances are the major building blocks for cell membranes. Enzymes couple GPC with the omega-3 fatty acid DHA, to make the phospholipid PC-DHA. This makes membranes especially fluid, enabling membrane proteins to perform with better efficiency. GPC produces PC-DHA in the skeletal muscles, wherein fluidity is essential for contraction. Muscles that function abnormally can show GPC deficiency.
4. GPC contributes to both male and female in reproduction. As spermatozoa mature, GPC is used to make PC-DHA that makes their membranes fluid to enable motility. With men, the lower their semen GPC the greater the likelihood of poor sperm motility and with it, infertility. Once semen is inserted into the female, an enzyme in uterine secretions breaks down the semen's GPC into substances that energize the sperm to achieve fertilization.
Dosing, Safety, Tolerability, Compatibility
Oral intake of GPC in the clinical trials was usually 1,200 milligrams (mg) per day, taken early in the day on an empty stomach. A reasonable dietary supplementation regimen is 1200 mg/day, taken in divided doses (AM and PM) between meals for 15-30 days, and thereafter 600 mg/day for maintenance. Symptomatic subjects can take 1200 mg/day until adequate improvement is achieved. Young, healthy subjects may experience benefit from daily intakes as low as 300 milligrams. GPC is very safe, being compatible with vitamins and nutrients and with pharmaceuticals. In clinical trial comparisons, GPC's benefits surpassed the nutrients acetylcarnitine and CDP-choline.
GPC: Nutrient for All Ages
GPC is unmatched for its support of active living and healthy aging. In some 23 clinical trials GPC improved mental performance in all functional categories. GPC can revitalize the aging brain, facilitating growth hormone (GH) release and boosting nerve growth factor actions. GPC's ample presence in human mother's milk suggests it could be conditionally essential. By supporting mental integrity, mind-body integration, the autonomic system, and the body's other organs, GPC enhances the active lifestyle. GPC is remarkable nutritional support for optimal health at any age.
Parris M. Kidd, PhD is a cell biologist trained at the University of California, Berkeley and San Francisco. Since entering the dietary supplement field in 1983, he has published many in-depth reviews of integrative medicine in the journal Alternative Medicine Reviews, and is science columnist for totalhealth magazine. Dr. Kidd is internationally recognized for his accomplishments in dietary supplement product development, documentation and quality control.
Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.