Search Term: " versus "

	Could eating chili peppers actually help you live longer?	Darrell Miller	2/17/19
	Drinking chilled yerba mate can help you achieve your weight loss goals	Darrell Miller	7/27/18
	Inflammation 101 – get smart for good health	Darrell Miller	10/18/17
	Want to Boost Your Memory Power? Green Tea May Help	Darrell Miller	7/31/17
	How to grow pesticide-free organic celery	Darrell Miller	4/4/17
	Study Says Inflammation Is Keeping You Fat	Darrell Miller	2/18/17
	Vitamin C is a powerful heart healer, especially after surgery	Darrell Miller	2/13/17
	Heart health: why low cholesterol is no longer the focus	Darrell Miller	12/18/16
	Many Kids Still Eating Too Much Salt	Darrell Miller	11/18/16
	Sugar: What Kinds to Eat and When	Darrell Miller	11/8/16
	What Is Monolaurin And What Are Its Health Benefits?	Darrell Miller	12/29/12
	What Makes Neptune Krill Oil So Good For Your Health?	Darrell Miller	3/24/12
	Can Royal Jelly boost Metabolism?	Darrell Miller	9/21/11
	Lycopene is More than Just a Tomato Extract!	Darrell Miller	2/8/11
	Myth: Agave Nectar may have adverse side effects such as mineral depletion, liver inflamma	Darrell Miller	4/8/10
	NOW Foods is the Leading Brand for Amino Acids in Health Food Stores	Darrell Miller	4/29/09
	Flax Seed Oil Supplement	Darrell Miller	12/29/08
	Herbs	Darrell Miller	10/9/08
	Tryptophan	Darrell Miller	7/3/08
	Do you experience muscle pain and inflammation?	Darrell Miller	4/25/07
	Smooth Move Tea - effective in Treatment of chronic constipation for Elderly Adults	Darrell Miller	3/12/07
	An Interview with Congressman Sam Farr, Representing California’s Central Coast.	Darrell Miller	5/30/06
	JOINT HEALTH	Darrell Miller	12/22/05
	Super Cortisol Support Fact Sheet	Darrell Miller	12/8/05
	Tru-E Bio Complex	Darrell Miller	12/8/05
	Green Tea Extract Fact Sheet	Darrell Miller	12/7/05
	Benefits of Green Tea	Darrell Miller	11/5/05
	Feds Subsidized Poor Nutrition	Darrell Miller	10/29/05
	Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)	Darrell Miller	8/2/05
	Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...	Darrell Miller	7/27/05
	Best Lutein Featuring Biolut Marigold Ext., 60 VC	Darrell Miller	7/27/05
	The Immune System - with Kyolic Garlic	Darrell Miller	7/11/05
	Bio-Chelation	Darrell Miller	6/29/05
	Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.	Darrell Miller	6/29/05
	REFERENCES	Darrell Miller	6/25/05
	REFERENCES	Darrell Miller	6/25/05
	Ginkgo: A Hair Tonic t hat Lowers Cholesterol Levels?	Darrell Miller	6/25/05
	CLA and Body Fat	Darrell Miller	6/22/05
	Snack Attack - we munch on about 125,000 pounds of pretzels, chips, popcorn and nuts a min	Darrell Miller	6/12/05
	Lose the Gluten - everyone who suffers from food allergies	Darrell Miller	6/10/05
	Allergy Alleviation	Darrell Miller	6/10/05
	Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...	Darrell Miller	5/24/05

Date: February 17, 2019 02:42 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Could eating chili peppers actually help you live longer?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6036)

Date: July 27, 2018 09:53 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Drinking chilled yerba mate can help you achieve your weight loss goals

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5681)

Date: October 18, 2017 01:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Inflammation 101 – get smart for good health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5349)

Date: July 31, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Want to Boost Your Memory Power? Green Tea May Help

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5067)

Date: April 04, 2017 06:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to grow pesticide-free organic celery

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4350)

Date: February 18, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study Says Inflammation Is Keeping You Fat

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3968)

Date: February 13, 2017 01:19 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin C is a powerful heart healer, especially after surgery

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3934)

Date: December 18, 2016 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Heart health: why low cholesterol is no longer the focus

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3668)

Date: November 18, 2016 03:04 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Many Kids Still Eating Too Much Salt

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3466)

Date: November 08, 2016 07:09 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Sugar: What Kinds to Eat and When

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3405)

Date: December 29, 2012 10:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Monolaurin And What Are Its Health Benefits?

Get An Immune Boost:

Man has made a big leap as far as science and pharmacology are concerned, but there are still a lot of substances useful to human health that are waiting to be discovered. There are also those substances naturally occurring but whose pharmacological properties have not yet been explored. Monolaurin, for instance, is a naturally occurring substance whose use in human health has only been lately discovered.

Monolaurin, also called glycerol monolaurate and glyceryl laurate, is a 12-carbon fatty acid as well as a monoglyceride. Although it is a derivative of coconut oil, it is most commonly prepared as a lauric acid mono-ester. Aside from coconut milk, it is also present in human breast milk, which is known to function as an immune protection passed on from mother to child after childbirth. The potency of breast milk as an immune barrier is evidenced by the stunted growth and frequency of infections seen in infants deprived of breast milk. But, all this is old information.

What's new about monolaurin?

Known Uses of Monolaurin:

Before we get to new information, it's important to look into the discovery of monolaurin. Way back in the 1960's, then University of Detroit professor Jon Kabara made an important discovery - that the combination of lauric acid and glycerol can be used in fighting germs. First marketed as a dietary supplement called Lauricidin, it was soon marketed by other pharmaceutical companies, but Lauricidin remains its most potent and purest form.

Since its discovery, it has been used as symptomatic treatment (and prevention) for the common colds, flu, herpes, and many other infections.

Working similarly to breast milk, it helps protect the immune system from infections and other ailments. Some Lauricidin users also claim that the substance is useful against Chronic Fatigue Syndrome and even autism. As for viruses, it has proven to be a useful supplement against HIV, Measles, Herpes Simplex, Epstein-Barr Virus, and Cytomegalovirus, to name a few.

Studies:

Recent studies have shown its in vitro antibacterial and antimicrobial activity, at least as far as superficial skin infections are concerned. Carpo, Verallo-Rowell and Kabara (2007) demonstrated the effectiveness of monolaurin versus common antibiotics in battling both gram positive and gram negative infections such as Staphylococcus and Enterococcus. Older studies have explained Monolaurin's mechanism of action - it inserts itself into the cell membrane, disturbs the cell membrane integrity of Gram positive bacteria, and therefore blocks cell replication.

Aside from medicinal uses, it is also used for other purposes as well. It is a common ingredient in many deodorants, thanks to its antimicrobial activity; body odor, as you may know, is caused by the presence of certain bacteria. It is also present in other products such as shampoo, detergents, soap, and even in certain foods such as ice cream and margarine.

Side Effects and Drug Interactions

As far as side effects are concerned, there is still a lot to be known. Some users may experience the Herxheimer Reaction, a complicated term that indicates the presence of fatigue, body ache, irritability and fever that may worsen before the medication takes effect. Use during pregnancy and breast feeding is contraindicated, given that not enough is known about its potential effects during this period. Dosage ranges from 0.75 to 3 grams, 2 or 3 times a day, and is taken after meals.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2792)

Date: March 24, 2012 05:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Neptune Krill Oil So Good For Your Health?

Neptune Krill Oil

Neptune Krill Oil is a dietary supplement that is made from the a species of Krill, a small crustacean that is quite similar to a shrimp. Neptune krill oil is rich in omega-3 fatty acids. These krills are supposed to be the largest biomass in the world and are found in the Antartic and North Pacific Oceans. While these shrimp like creatures are small in size, there is an estimate of 500mn tons of krill in the ocean. Neptune Technology has the patent for krill oil extraction and hence the krill oil that is found as supplement comes from Neptune Technologies only. As Krill form important part of the food chain, especially in the Antartic region, there have been many krill farms being setup for harvesting of krill.

Health Benefits

Krill oil has many health benefits and is used as a dietary supplement as it contains important nutrients like omega-3 fatty acids similar to those found in fish oil, omega-3 fatty acids conjugated to phospholipids and astaxanthin. Lets us see what benefits of Neptune krill oil are:

Blood Sugar and Hyperlipidemia: Recent studies have shown the beneficial effects of krill oil in lowering blood sugar levels and totalcholesterol. Neptune Krill oil helps in lowering bad cholesterol (LDL), blood sugar, triglycerides and total cholesterol:HDL ratio. Hence it keeps your heart healthy and fit.

Premenstrual Syndrome: Neptune Krill oil is an effective and natural way to manage the symptoms of premenstrual syndrome. It not just gives relief from the physical symptoms such as bloating, breast tenderness and fatigue, but also helps in controlling the emotional symptoms (irritability, stress and depression) experienced by many women during their menses.

Inflammation relief: Studies have indicated that daily intake of krill oil helps in improving the joint health and thus helps in reducing inflammation and pain of arthritis.

Reduces risk of Cancer: Omega-3 fatty acids have anti-carcinogenic properties. Consumption of Neptune krill oil could reduce the risk of cancer. Studies have even shown that krill oil helps slowing down the growth of cancerous tumors.

Fish oil versus Krill oil: Which one is better?

Fish oil vs Krill oil is the most common debate that is becoming popular among health enthusiasts. This is because both Fish oil and Krill oil are the daily nutritious supplements that are loaded with potential health benefits. In essence, both of these oils share same characteristics in terms of their composition and their properties but still the comparisons between these two healthy oils continue. Let us discuss the pros and cons of fish oil vs krill oil and compare different parameters to decide it by ourselves, which one is better?

1. Krill oil contains higher amounts of anti-oxidants (astaxanthin) that are quite beneficial for health while many manufacturers add anti-oxidants from outside in fish oil.

2. Both the oils are rich source of omega 3 fatty acids, but fish oil contains high concentration of harmful metals that can cause unwanted side-effects if consumed.

3. Fish oil is made commercially from farm raised fish, which lacks useful nutrients, whereas krill oil is made from the pristine waters of Antarctica.

Krill oil is nature's rich source of important nutrients. Neptune krill oil is a vital supplement that has many health benefits.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2617)

Date: September 21, 2011 12:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Royal Jelly boost Metabolism?

Overview

The metabolism is becoming more and more well known in any community all across America as something to look at when we are talking about health and wellness as this is the source of all calorie burning and at the end of the day will help you lose weight. This is, in so many ways the bottom line, losing weight will make you and keep you healthy. In these times of a fast paced life where anyone and everyone is so busy to even worry about how much calories they eat versus how much they need, a need for alternative solutions aside from just working out and making sure that more calories are burnt than eaten is needed and the scientific community acknowledges that need as proven by the tons of research done regarding weight loss and embraced by the manufacturers as they are more than willing to provide us with what we need. So through all these studies, the logic of looking at the metabolism and how to boost it all seems natural and this is why.

Metabolism

The word metabolism is taken from the greek language and basically means change or transformation. In simple terms metabolism is defined as the amount of energy or calories your body burns at a given period of time. Whatever we are doing, no matter if we are active or at rest we are burning energy and if compared to a car, it’s like burning fuel and the car can be turned off but us on the other hand could not. Even when sleeping we are still essentially burning up fuel, just the very fact our brain still works and we are breathing while we are asleep is already a sign that we are burning energy.

Now where it will interest us in terms of energy and overall strength is that metabolism is based on a person’s body composition and fat tends to need less energy to maintain itself as it is not an active tissue compared to having lean muscle because it continually needs more and more calories to maintain itself therefore more muscle means faster metabolic rate. Now this is where we go back to the fact that we need help when it comes boosting metabolism aside from just increasing muscle, because that is so much harder than supplementing with something all natural like Royal Jelly.

Royal Jelly and Energy Boost

Royal jelly is an animal product and derived solely from honey bees secretions. Its main function in terms of affecting the metabolism comes from its unique combination of compounds that will aid the enhancement of energy production in the cells. This combination is composed of amino acids, trace minerals, monosaccharides and enzymes that have bioactive properties. Among the vitamins that it will provide naturally is the vitamin b-complex. This family of vitamins is well known for its muscle tissue building and energy boosting attributes. Another way that researches feel is a way it increases energy is through promoting overall well being since royal jelly has been related to increased production of several neurotransmitters in the body like serotonin and dopamine.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2448)

Date: February 08, 2011 04:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lycopene is More than Just a Tomato Extract!

Lycopene is a naturally occurring antioxidant, and a very powerful one at that. Like beta-carotene, it is a carotenoid, a phytochemical that gives certain plants their orange or bright red pigmentation. While lycopene belongs to a group of carotenoids called carotene, known precursors of vitamin A, it does not get converted into vitamin A inside the human body, which is not a bad thing, inasmuch as lycopene in itself exhibits antioxidant properties that surpass the effects of vitamins.

Tomatoes are very rich in lycopene, and indeed consumptions of tomatoes have been reported to show the antioxidant properties of lycopene. Papayas, pink guavas, and watermelons are also good sources of this compound, but the plant source identified to have the highest concentrations of lycopene is Gac, in English also known as Sweet Gourd, a bright red fruit native to Southeast Asia and largely unknown to the rest of the world. With that, a significant fraction of the total lycopene consumption worldwide is derived from tomatoes.

Reactive Oxygen Species (ROS)

Chemical reactions in the human body that respond to the presence of oxygen are part of a process called oxidation, which takes place everywhere else in nature. These reactions entail a change in the oxidation number of atoms or molecules involved in the movement of electrons between molecules inside the body, giving rise to toxic by-products collectively known as reactive oxygen species.

When cells produce the energy that they use to power their physiological functions, they also produce reactive oxygen species, or ROS, which is now believed to be a key factor in the progression of physical infirmities associated with the aging process of human beings and other mammals. That being said, ROS are actually in the employ of the immune system, and particularly effective against pathogens, which may be invasive extracellular matter or harmful microorganisms.

Every single cell make use of enzymes that change the chemical makeup of unnecessary ROS, which must always be kept in check as they damage cells even at low amounts. These enzymes outmaneuver the damaging activities of ROS, thereby protecting the cells. In spite of that, the human body is known to produce more ROS as we age or during long-standing exposure to stress.

Lycopene versus ROS

One type of ROS is singlet oxygen, a form of oxygen that is highly reactive to free radicals. In fact, singlet oxygen is a known catalyst of free radicals especially when it gets excited at the molecular level. Lycopene is the best known carotenoid to counter the damaging effects of singlet oxygen in the human body, and reported to have antioxidant properties far superior to vitamin E and glutathione.

The good thing about lycopene is that its bioavailability compounds when exposed to heat, so cooking tomatoes actually brings out the goodness of this chemical compound. Lycopene acts against the proliferation of cancer cells in a number of mechanisms, and, to date, there have been innumerable reports in support of the role of lycopene against most known types of cancer.

Have you had your Lycopene today?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2232)

Date: April 08, 2010 04:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Myth: Agave Nectar may have adverse side effects such as mineral depletion, liver inflamma

Myth: Agave Nectar may have adverse side effects such as mineral depletion, liver inflammation, hardening of the arteries, insulin resistance leading to diabetes, high blood pressure, cardiovascular disease, obesity and more.

Truth:

This is an unfounded scare tactic. Moderate use of Agave Nectar will not directly lead to the above mentioned consequences. The issue is overconsumption and poor dietary choices.

“Inaccurate information from ostensibly reliable sources and selective presentation of research under extreme experimental conditions, representing neither the human diet nor HFCS have misled the uninformed and created an atmosphere of distrust and avoidance for what, by all rights, should be considered a safe and innocuous sweetener.” – White, John S. The Journal of Nutrition. We believe this applies to agave as well.

Supporting data has been misused. The studies that have been conducted have measured metabolic upsets under extreme conditions. They have used pure 100% fructose versus pure glucose at very high concentrations. These conditions do not reflect the American diet or the composition of fructose containing sweeteners. The methods have been inappropriate for assessing the safety of these dietary macronutrients. Even pure water triggers adverse health effects at these high repeat doses. The Journal of Nutrition (2009). Supplement: The State of Science on Dietary Sweeteners Containing Fructose.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2143)

Date: April 29, 2009 04:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NOW Foods is the Leading Brand for Amino Acids in Health Food Stores

-Michael Lelah, Ph.D. / Technical Director

It was recently announced that NOW Foods is now the leading brand for the amino acid segment in Health Food Stores. We sell over 100 different formulas of single and multiple amino acids in powder, capsule, tablet, and liquid forms. We cover the alphabet from L-Arginine to L-Tyrosine, with high potency products such as Acetyl L-Carnitine 750 mg, 1,000 mg L-Carnitine Tartrate, and our new 1000 mg L-Tryptophan Tabs coming in June. Most amino acids come in two optical forms – the L-form and the D-form. The L-form is the only true natural form, while the more common D- and DL-forms are synthetic. At NOW Foods, we only carry the natural L-form. This is the safest form, naturally found in foods and in the human body. Taurine and Glycine have no optical rotation, and therefore occur in only one natural form with no L- or D- designation.

Our L-amino acids are of the highest quality available, and our ingredient powders conform to USP standards. The USP standards cover identity, purity and potency testing. This means that each lot of amino acid ingredient is tested to ensure that (a) it really is the amino acid we say it is, and not something else, (b) it’s pure to the highest USP standards, and (c) it has the full potency that you require. At NOW Foods, we take our amino acids seriously, and we even go beyond the USP level of testing when we believe it is necessary. For example, every lot of our L-Tryptophan is tested to ensure that it is free of Peak E. This is the impurity which is believed to have been responsible for serious adverse events twenty years ago. We rigorously enforce this standard, and this goes beyond USP requirements. We have rejected a number of lots of L-Tryptophan because of the presence of Peak E. We will not sell you these rejected materials, and we hope that others do not as well. We can’t control what others do, but we can control what we do and we assure you of L-Tryptophan tested to be free of Peak E.

Our state-of-the-art analytical labs allow us to perform our own testing on our amino acids to doubly ensure their quality. We have 9 HPLCs that we use every day to test and retest our aminos to confirm their potency, purity and identity. We have very strong analytical, professional, and technical staff members who have many years of experience in testing amino acids. So much so that we are involved in developing industry validated methods for L-Carnitine and L-Arginine. NOW scientists are setting the standards for amino acid testing.

Most amino acids are quite stable and they can be packaged in standard containers. These amino acids will maintain their shelf life through their Best By date, and we test to make sure they do. SAMe however, is a uniquely unstable amino acid compound. Because of this, we provide triple protection – glass bottles, moisture control and oxygen control. SAMe is distinctly susceptible to oxygen degradation. We are the only major brand to offer our SAMe packaged with Ageless® oxygen absorbing packets, which remove integrity-challenging oxygen from every bottle to reduce degradation. We go that one step further to protect our products! Finally, we’re the leading amino acid brand because our products work. As an example, in a published study2, our SAMe was directly compared against the leading drug – Celebrex®.

NOW Foods brand SAMe performance was the same as the drug supporting joint health, but without the pharmaceutical side effects. All in all, we are not the leading brand in this category just because of our great prices. We have significant science and quality behind all of our products, not just amino acids, and we hope that you consider our rigorous efforts in quality assurance, safety and efficacy when making a purchase.

1. SPINScan Natural Channel, 52 weeks ending 02.21.09. 2. Najim, W.I., et al, SAMe versus celecoxib…, BMC Musculoskeletal Disorders 2004, 5:6.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2000)

Date: December 29, 2008 01:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Flax Seed Oil Supplement

The majority of Americans know to some extent that there is a an association between a high-fat diet and serious health problems including heart disease, high cholesterol, diabetes complications, and cancer. However, what a lot of people are unaware of is that the kind of fat that we take into our bodies is as important as regulating the amount.

This notion was first observed by researchers in the early 1950s and is made particularly clear when observing the Eskimo diet versus the standard American diet. Because Eskimos routinely eat a diet that is full of animal fat, it is a wonder why they do not suffer from the cardiovascular disease that is associated with these foods as Americans do.

The explanation of this is because Eskimos eat a great deal of fish, which is a food that is high in unsaturated fats, which work to prohibit the harmful effects that saturated fats produce. Saturated fat is often associated with harmful disease, and comes from animals, while unsaturated fat comes from vegetables and can actually work to inhibit the effects of saturated fats. Put simply, it is safe to say that the two types of fats work to cancel each other out. Saturated fats found in foods such as margarine, shortening, and most prepared foods negatively affect the way that the body uses unsaturated fats, while the reverse is also true.

A diet that is low in levels of saturated fats ad high in levels of unsaturated ones can help to protect the body against heart disease and cancer. This counteractive effect works because of the presence of two specific fats which function as essential fatty acids, which are needed in the body in order to properly function. However, the body cannot produce these essential fatty acids on its own and without them, deficiency symptoms develop and growth ceases. Because the body can not produce its own essential fatty acids, it relies on food sources that supply them. The problems result because the typical American diet does not provide a sufficient amount of essential fatty acids.

There are two primary types of essential fatty acids: linoleic and alpha-linolenic acid, the body needs both of these acids in order for it to function properly and have normal cellular structure. The main difference between the two is basically a structural one, leading two the identification of two different oils: omega-3 and omega-6. A balance of these two oils is needed by the body in order for it to function at an optimal level.

Linoleic acid is responsible for transportation of water across the skin and the proper functioning of the pituitary gland. It is beneficial in the treatment of many skin conditions and in growth and development therapies. Alpha-linolenic acid, on the other hand, offers protective effects against coronary heart disease and stroke and benefits those who are suffering from migraines, arthritis, and high cholesterol levels.

There are two main sources of fatty acids: fish oil and flaxseed oil. Fish oil has many benefits, while flaxseed oil may have greater benefits at a more economical price. If one doesn’t like the smell of fish then the flaxseed oil alternative is more appealing and has very little smell while still retaining the health benefits that omega supplements provide.

--
Buy Flaxseed Oil at Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1954)

Date: October 09, 2008 01:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs

Herbs have been used for a long time as foods to heal disease in our human society. It can be estimated that herbs have been used by humans for at least 15,000 years, with animals using the herbs as medicine for much longer. They, fortunately, had the instinct to search and find the herb they need when it is needed, while our animals of today are limited by fences. Many veterinarians claim that horses will go out and look for a plant that will be helpful to get them to get rid of a parasite when they have it. This plant is called Wormwood. A lot of the first herb uses were actually learned from observing and ill animal and watching it go out and get a plant. Man then followed and ate the plant himself.

The Indians in South American discovered that the Pau d’Arco tree possesses a lot of medicinal ability in the inner back by observing that the inner bark repelled the insects that flooded other trees in the rain forest. The Indians also found a bush that is found in a certain canyon increased their eyesight, so they named it Eyebright. Similarly, the Arizona Apache and Pima Indians found that if they took a twig of the Chaparral bush and heated it and placed it in or next to a tooth hoe, the pain and infection were relieved.

Because of the above, it can be inferred that man has been using herbs for an extremely long time. This is important, especially when taking it to comparison just how short-term the use of chemicals has been. There is no doubt to anyone that chemical use over a long period of time causes a negative effect on the human body. It seems extremely odd that the scientific community prefers their scientific laboratory experiments with chemicals over 4,000 to 5,000 years of herb use. It seems as if someone would see the inadequacy of trying to find a medicine in laboratories by working with animals over a period of months versus the use of herbs by humans in their natural habitat for thousands of years.

Chemicals are not food for the human body as they have all sorts of negative effects including unwanted immune responses which cause inflammation. They do not provide any nutritional affects. Herbs, on the other hand, are foods that fuel the human body, nourishing it and also cleansing it so that it may be energized. Additionally, these herbs have a lot of unknown positive effects. This seems so simple that some wonder how anyone in a professional status could see the truths in prescribing a drug for their spouse or client. A lot of times it is suggested that patients ask their doctors if they would prescribe the same drug or surgery for their wife or children. We need to become aware of the responsibility we have to our bodies. Many herbs have Glyconutrients and polysaccharides that can feed the immune system. These Glyconutrients or polysaccharides are simple sugars that provide raw materials for the body to build its self better and stronger. Every cell in the body is wrapped with instructions. When the immune system come in contact with each cell, it determines whether its friend or foe. Herbs can help the body build its self better.

Those people who ask if they will become dependant on an herb are thinking of the herbs as a drug instead of food. Although we are dependant on food, it is better to eat food that has been proven to help our body, rather than one which will poison it. Herbs are foods that have proven elements involved which will provide a positive effect on our body. Each specific herb can provide a specific need to our body.

--
Buy Herbs at Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1910)

Date: July 03, 2008 08:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Tryptophan

Serotonin has not only been shown to regulate sleep, but it also is responsible for controlling mood, including feelings of optimism, relaxation, general sense of well-being, and the ability to focus and concentrate. When serotonin levels drop, it can lead to a lowered mood, which is what people experience with seasonal affective disorder, premenstrual syndrome, and general stress. People who experience these conditions also have been shown to experience decreased levels of tryptophan, which is responsible for the decrease in production of serotonin. Tryptophan depletion has been associated with a lowering in mood of normal healthy men. In one study, women who had recovered from major depression and ended drug treatment experienced temporary but clinically significant depressive symptoms after tryptophan depletion. In many studies that were performed in the 1970s, indications of trytophan’s ability to relieve lowered mood were found.

When shorter days begin in the fall and winter, negative effects on a significant percent of the U.S. population result. Some experience sadness, sleepiness, increased appetite, weight gain, and a loss of libido, which is what is known as seasonal affective disorder (SAD). A key contributor to this is the increased synthesis of melatonin that occurs during the winter months. Daylight normally inhibits the conversion of serotonin into melatonin. Since the period of nighttime is longer in the winter versus the summer, there is a longer period of melatonin secretion. Increased synthesis of melatonin depletes serotonin levels, which, in turn, increase the symptoms of SAD. Those patients who experience SAD tend to crave starchy foods and sweets more, which happens when brain serotonin levels are low.

Tryptophan treatment may offer a substantial amount of help for people who are suffering from seasonal affective disorder. SAD patients who were treated with either light therapy or with tryptophan proved that patients with light therapy relapsed more quickly after the discontinued use, as apposed to those who were treated with tryptophan. Studies have also shown that SAD patients often feel better after being treated with tryptophan.

Serotonin also plays an important role in behavioral inhibition. Many studies have found that there is a decrease in aggressive behavior when serotonin is increased, while decreasing serotonin leads to impulsive aggressive behavior. Another study proves that healthy men who are depleted of tryptophan show more aggressiveness. When tryptophan supplementation was studied, participants who received the tryptophan significantly decreased their quarrelsome behavior and increased in sociable and agreeable behavior. Additionally, those patients’ perceptions of other participants’ agreeableness also increased.

Symptoms that are related to premenstrual syndrome include depression, cravings for foods that a rich in carbohydrates, insomnia, irritability, and hostility. More so, women with premenstrual syndrome dysphoria, which is a more severe premenstrual syndrome, have shown decreased levels of brain serotonin. This suggests that tryptophan may be involved, as premenstrual women who had tryptophan depletion have shown increased aggressive behavior. When tryptophan supplementation was studied on women who experienced premenstrual dysphoric disorder, mood swings, tension, and irritability, results showed that there were significantly greater improvements with l-tryptophan supplementation than with a placebo.

--
Boost Mental Health With Tryptophan at Vitanet ®. LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1831)

Date: April 25, 2007 03:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Do you experience muscle pain and inflammation?

--
Improve Flexability with Vitamins at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1529)

Date: March 12, 2007 12:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Smooth Move Tea - effective in Treatment of chronic constipation for Elderly Adults

In a randomized, double blind, placebo-controlled clinical study, smooth move tea, a traditional formula for relief of occasional constipation, caused a statistically significant increase in the number of bowel movements.

The study was carried out with nursing home residents with chronic constipation at a 483-bed nursing home in Allentown, Pennsylvania. The lead investigator was Dr. Sam Bub, Medical Director of Cedarbrook Nursing Home, a nursing facility for Lehigh county residents in need of short or long-term nursing care.

Profile: Dr. Sam Bub, MD

Lead Investigator in Smooth Move Clinical Trial

Dr. Bub first learned about Smooth Move tea from a patient who had used the tea and found it effective. From this experience he suggested the tea as a treatment to other patients who had similar complaints of constipation and to his pleasant surprise his patients continued to have positive responses. As a result of this Dr. Bub contacted Traditional Medicinals to suggest conducting a clinical trial of smooth move tea in a nursing home to see if the product would work under those circumstances. At the end of the study they found that there was a statistically significant improvement in the number of bowel movements for those taking the herbal tea versus the placebo. Even more important the research concluded that there had been absolutely no adverse effects from the use of the herbal product.

Dr. Bub things “the future of herbal medicine is bright provided companies do research to see that their product really works.” Smooth Move tea has been “available now for many, many years and it has stood the test of time.”

Dr. Bub is a board certified in Family Practice and Geriatrics. He is also the Medical Director for Cedarbrook County Home in Pennsylvania.

--
Buy Traditional Medicinials and other Great Teas at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1491)

Date: May 30, 2006 02:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: An Interview with Congressman Sam Farr, Representing California’s Central Coast.

Ambassador to Health Profile

An Interview with Congressman Sam Farr, Representing California’s Central Coast.

Congressman Sam Farr, a fifth-generation Californian, represents the state’s beautiful central coast. His district encompasses the length of the big Sur coastline in Monterey County, the Monterey Bay National Marine Sanctuary, the Salinas Valley “Salad bowl,” the redwoods, mountains and beaches of Santa Cruz County, and the majestic rural landscape of San Benito County. The health and wealth of this region has been strengthened by Rep. Farr’s focus on the environment, education and the economy. Rep. Farr was raised in Carmel, California and graduated from Willamette University with a BS in biology. He later attended the Monterey Institute of International Studies and the University of Santa Clara. He is fluent in Spanish. As a tough advocate for the health food industry, he has lobbied for strict federal organic standards.

Todd: Congressman Farr, thank you for taking the time to speak with us! Id also like to thank you for all the great things you’ve done for our community, form funding marine sanctuaries and authoring the Ocean’s Act to expanding Pinnacles national Monument. The League of Conservation Voters and others have recognized you as an “Environmental Hero”. And, you’ve worked hard to support the economic vitality of central coast’s $3 billion agriculture industry which includes a substantial organic segment. Our backyard here is also the home of a robust group of nutritional supplement manufacturers. An estimated 187 million Americans are currently taking dietary supplements as part of their daily healthy diet. In California, we’ve got 792 natural product manufacturers and distributors. Where do you stand on the state of our industry?

Congressman Farr: Well, thank you for the introduction and for asking to talk to me about nutritional supplement issues. I am very supportive of this industry and include myself in the 187 million Americans taking dietary supplements. I think supplements offer many safe and viable tools to maintain your health. The continued growth of this industry is an indication of both consumer confidence in the products and the products’ ability to fill the gaps where conventional medical care falls short.

Todd: It is estimated that by 2030, more than 70 million Americans will be over the age of 65 and the cost of health care could reach $16 Trillion per year. A recent study by the Lewin Group showed that by taking certain dietary supplements, seniors can lead healthier, more productive, independent lives while saving billions in reduced hospitalizations and physician services. Do you share our view that a Wellness Revolution is needed to counter the dilemma of an aging population versus shrinking health care support in the future?

Congressman Farr: Our health care system is definitely facing a challenge, especially as the Baby Boomers hit their 60’s and Americans are living longer than ever before. As a Baby Boomer myself, I am well aware of America’s aging population and the impact that will likely have not only on our social institutions but also our fiscal well-being. I agree that dietary supplements do play and will play an even larger role in the future as more seniors look for a way to augment their diets in order to stay healthy and active longer than past generations.

Todd: Our industry is regulated by DSHEA (the Dietary Supplement Health and Education Act), which was passed unanimously by Congress in 1994 to create a reasonable regulatory framework for access to, information about, dietary supplements. But many say that the FDA and DSHEA weren’t adequately funded to do the job as tasked. “Supplements are unregulated” is a false argument we sometimes hear. To ensure that the FDA is able to carry out the law as Congress intended, Representatives Dan Burton (R-Ind.) and Frank Pallone (D-N.J.) introduced H.R. 2485, the DSHEA Full Implementation and Enforcement Act of 2005. Did you support this bill and where does it stand today?

Congressman Farr: I think the DSHEA is a critical law and was proud to support it when Congress considered it in 1993 and 1994. I would certainly support H.R. 2485 if it came up for a vote in Congress. Unfortunately this bill has not moved since it was first introduced and referred to the Subcommittee on health in the house energy and commerce committee. Since this is an election year we have a tight schedule with only about 60 legislative days scheduled before we adjourn. That means it’s likely Congress will only finalize bills such as the appropriation bills that fund government before adjournment.

Todd: Our business climate has included some valid and rigorous challenges to improve our industry, from good manufacturing practices (GMP), to allergy labeling, to implications of Prop-65 in California. It’s disconcerting that a new bill, H.R. 3156 The Dietary Supplement Access and Awareness Act would try to capitalize on misconceptions about the industry. In an era of declining health care and declining insurance coverage, this bill would regulate supplements as prescription drugs. Among other things, it would also require adverse event reports to be turned over to the FDA, even though other foods, including those with identical ingredients, do not have the same requirements. This has the potential to be the next Prop-65-like Lawsuit mill. The result of H.R. 3156 would be chilling. It will knock smaller producers out of the market. It will result in higher prices for all supplements. It will decrease the availability of health-giving supplements to the public. What’s your feeling on this?

Congressman Farr: I am similarly concerned about H.R. 3156 and would oppose it if it came up for a vote in Congress. Like H.R. 2485, this legislation has been referred to a subcommittee on Health in the House Energy and Commerce Committee without any further action. The supplement industry has worked in good faith with the FDA since passage of DSHEA and H.R. 3156 would re-invent a wheel that isn’t needed. Instead, adequate funding as proposed in H.R. 2485 would provide ample oversight for the industry.

Todd: According to a recent study, 72% of the general population believe the government should fund more research on health benefits of nutritional supplements. Do you agreen and what can be done to meet this need?

Congressman Farr: I definitely agree that the federal government should play a bigger role in support of research regarding the health benefits of nutritional supplements. As a member of the House Appropriation Committee, I sit on the subcommittee that has jurisdiction over the FDA’s budget and I know the tight fiscal restraints the agency is under. I’ve worked with my colleagues to provide adequate funding, but it’s an uphill battle especially when we’re in a “robbing Peter to pay Paul” kind of situation. I recommend that people within the industry organize and use your consumer base to actively lobby Congress for additional funds. I’m fond of reminding people that the squeaky wheel gets grease – so let every Congress member and Senator know how much this issue matters to you.

Todd: When there is overwhelming scientific evidence that nutritional supplements provides relief for a disease condition, it currently takes a lawsuit to get the FDA to relent and allow the claim. Even then, the FDA strictly limits the claim and requires a disclaimer that does more harm than good in communicating this important information to the public. There is a new bill, H.R. 4282, The Health Freedom Protection Act that would end FDA and FTC censorship of health information. As an example, the 50% of all adult males who suffer from an enlarged prostate could receive relief from that condition by consuming a simple and safe ingredient, saw palmetto derived from the fruit of the dwarf American palm tree. The FDA censors that information. The public deserves a better opportunity to be informed about omega-3 EFA and heart disease, folic acid and birth defects, phosphatidylserine and cognitive impairment. Do you agree and do you support this bill?

Congressman Farr: I agree the public needs to access to the best information possible so they can make well informed choices about their health. I likely would support H.R. 4282 if it came up for a vote in Congress. Unfortunately this bill is in a similar situation as other we’ve mentioned in this interview – and again because of the tight schedule of an election year, it’s unlikely action will happen this year.

Todd: According to the barometer study, 85% of the US population is currently using some type of dietary supplement. Do you? Looking at your busy schedule from co-chairing the House Oceans Caucus to your seat on the Travel and Tourism Caucus, you are one busy congressman! Are you popping nutritional supplements please tell us!

Congressman Farr: I do take some nutritional supplements, though they vary and since Ginkgo Biloba isn’t among them I cant remember their names off-hand! One product I do use faithfully is Airborne to help me combat germs and colds that I might get from sitting on an airplane. But, like many Americans my life is over-scheduled and combined with the amount of air-travel I do, I find nutritional supplements helpful as I try to stay healthy despite my hectic lifestyle.

Todd: Thank you Congressman Farr! Live long and prosper!

Todd Williams; Source Naturals Marketing Programs Manager.

--
Health and Wellness update at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1288)

Date: December 22, 2005 09:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: JOINT HEALTH

Glucosamine & Chondroitin - JOINT HEALTH

Everyone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints.

Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of mobility. These nutrients are referred to as “chondroprotective agents,” and include glucosamine and chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with glucosamine and chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function.

Glucosamine and chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.

GLUCOSAMINE

Glucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on glucosamine sulfate and glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion.

The 106 patients on placebo had a progressive jointspace narrowing, while participants taking glucosamine experienced no significant joint-space loss, indicating glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of glucosamine sulfate or placebo daily for 30 days. The patients treated with glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5

CHONDROITIN

Chondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While glucosamine helps manufacture and maintain cartilage, chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6

NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both glucosamine and chondroitin as separate products, as well as in powder and lotion forms.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1064)

Date: December 08, 2005 07:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Super Cortisol Support Fact Sheet

Super Cortisol Support Fact Sheet

LIKELY USERS: People under a lot of stress; People who suffer from stress-related eating; People who may have metabolic syndrome (Syndrome X);

KEY INGREDIENTS: Relora®13, Rhodiola14-20, Reishi 21-24, Green Tea Extract25-32, Holy Basil, Ashwaganda, Banaba, Pantothenic Acid, Calcium Ascorbate, Magnesium, Lecithin, Chromium

MAIN PRODUCT FEATURES: NOW® Super Cortisol Support is an herbal and nutritional formula designed to support healthy adrenal function and maintain healthy cortisol levels. The adrenal glands help the body respond and adjust to stress generated from both internal and external forces. Under chronic stress, cortisol can be overproduced, resulting in weight gain and difficulty in managing healthy blood sugar levels. Super Cortisol Support combines adaptogenic herbs with Chromium, Corosolic Acid and Relora® to help the body manage the negative effects of stress such as abdominal obesity, overeating and low energy levels.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy energy levels throughout the day1-6. Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy immunity1-9. Along with Chromium, and Corosolic Acid, these herbs also help to support healthy serum glucose levels1-12. Relora® has been included in this formula to alleviate symptoms associated with stress such as irritability and nervous tension13.

This formula is recommended by Hyla Cass, MD.

This is the first Cortisol formula to use Relora®, a natural proprietary blend of a patented (U.S. Patent No. US 6,582,735) extract of Magnolia officinalis and a patent-pending extract from Phellodendron amurense. Relora® was developed as an ingredient for dietary supplements and functional foods that could be used in stress management and for stress-related appetite control. This patented blend of plant extracts is the result of screening more than fifty plant fractions from traditional plant medicines used around the world. Relora® has excellent stress management properties without causing sedation. Overweight adults may have excessive abdominal fat due to stress-related overeating. Relora® appears to maintain healthy hormone levels in stressed individuals and act as an aid in controlling weight and stress-related eating.33

SERVING SIZE & HOW TO TAKE IT: One capsule, two to three times a day.

COMPLEMENTARY PRODUCTS: Holy Basil, Green Tea, L-Theanine, Licorice Root, Vitamin C, Eleuthero Root, Pantothenic acid

CAUTIONS: None.

SPECIFIC: Some of these ingredients may support the body’s blood sugar controls, so people taking blood sugar medications should inform their physician before using Super Cortisol Support, and their glucose should be monitored when taking this formula so their medication strength can be modulated appropriately to avoid an overdose of medication. No side effects have been noted for this dosage of Relora®.

GENERAL: Pregnant and lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV (2000) Phytomedicine 7(2):85-89.
2. Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H (2000) Phytomedicine 7(5):365-371.
3. Bhattacharya SK, Battacharya A, Sairam K, Ghosal S (2000) Phytomedicine 7(6):463-469.
4. Sembulingam K, Sembulingam P, Namasivayam A (1997) Indian J Physiol Pharmacol 41(2):139-143.
5. Archana R, Namasivayam A (2000) J Ethnopharmacol 73:81-85.
6. Lin Z-B, Zhang H-N (2004) Acta Pharmacol Sin 25(11):1387-1395.
7. Monograph (2002) Alt Med Rev 7(5):421-423.
8. Agarwal R, Divanay S, Patki P, Patwardhan B (1999) J Ethnopharmacol 67:27-35.
9. Archana R, Namasivayam A (2000) J Ethnopharmacol 73:81-85.
10. Vincent JB (2000) J Nutr 130:715-718. 11. Judy WV, Hari SP, Stogsdill WW, Judy JS, Naguib YMA, Passwater R (2003) J Ethnopharmacol 81)1):115-117.
12. Lin Z-B, Zhang H-N (2004) Acta Pharmacol Sin 25(2):191-195.
13. Maruyama Y, Kuribara H, Morita M, Yuzurihara M, Weintraub ST (1998) J Nat Prod 61:135-138.
14. Brown RP, et al. American Botanical Council. Rhodiola rosea: a phytomedicinal overview. g/herbalgram/articleview.asp?a=2333.
15. Kelly GS. Rhodiola rosea: a possible plant adaptogen. Alt Med Rev 2001;3(6):293-302.
16. De Bock K, et al. Acute rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab 2004;14:298-307.
17. Shevtsov VA, et al. A randomized trial of two different doses of a SHR-5 rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine 2003;2-3(10):95-105.
18. Shugarman AE. Men’s Fitness, 2002. As reported on: LookSmart FindArticles. Energy pills that work: can these five supplements help unleash the muscle building power within you? ttp://findarticles.com/p/articles/mi_m1608/is_3_18/ai_83343009/
19. Earnest CP, et al. Effects of a commercial herbal-based formula on exercise performance in cyclists. Med Sci Sports Exerc 2004;36(3):504-9.
20. Wing SL, et al. Lack of effect of rhodiola or oxygenated water supplementation on hypoxemia and oxidative stress. Wilderness Env Med 2003;14(1):9-16.
21. Shu HY. Oriental Materia Medica: A Concise Guide. Palos Verdes, CA: Oriental Healing Arts Press, 1986, 640–1. 22. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.
23. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.
24. 9. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
25. Kono S, Shinchi K, Ikeda N, et al. Green tea consumption and serum lipid profiles: A cross-sectional study in Northern Kyushu, Japan. Prev Med 1992;21:526–31.
26. Yamaguchi Y, Hayashi M, Yamazoe H, et al. Preventive effects of green tea extract on lipid abnormalities in serum, liver and aorta of mice fed an atherogenic diet. Nip Yak Zas 1991;97:329–37.
27. Sagesaka-Mitane Y, Milwa M, Okada S. Platelet aggregation inhibitors in hot water extract of green tea. Chem Pharm Bull 1990;38:790–3.
28. Stensvold I, Tverdal A, Solvoll K, et al. Tea consumption. Relationship to cholesterol, blood pressure, and coronary and total mortality. Prev Med 1992;21:546–53.
29. Tsubono Y, Tsugane S. Green tea intake in relation to serum lipid levels in middle-aged Japanese men and women. Ann Epidemiol 1997;7:280–4.
30. Serafini M, Ghiselli A, Ferro-Luzzi A. In vivo antioxidant effect of green tea in man. Eur J Clin Nutr 1996;50:28–32.
31. Benzie IF, Szeto YT, Strain JJ, Tomlinson B. Consumption of green tea causes rapid increase in plasma antioxidant power in humans. Nutr Cancer 1999;34:83–7.
32. Sasazuki S, Komdama H, Yoshimasu K, et al. Relation between green tea consumption and severity of coronary atherosclerosis among Japanese men and women. Ann Epidemiol 2000;10:401–8.
33. Sufka KJ, et al. Anxiolytic properties of botanical extracts in the chick social separation-stress procedure.Psychopharmacology. 2001 Jan 1;153(2):219-24. PMID: 11205

--
buy cortisol support at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1003)

Date: December 08, 2005 04:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Tru-E Bio Complex

Tru-E Bio Complex TM

LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed

MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements.

NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32

Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32

This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7

Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols.

All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU).

Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet.

Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market.

We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32

Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23

SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal.

SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds

CAUTIONS: None.

SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

REFERENCES:

1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
2. Schneider C (2005) Chemistry and biology of vitamin E. Mol Nutr Food Res 49(1):7-30.
3. Pfluger P, Kluth D, Landes N, Bumke-Vogt C, Brigelius-Flohe R (2004) Vitamin E: underestimated as an antioxidant. Redox Rep 9(5):249-254.
4. Liu M, Wallin R, Saldeen (2002) Effect of mixed tocopherols on ecNOS, SOD, and PKC in leukocytes in human subjects. Nutr Res 22:1253-1263.
5. Saldeen T, Li D, Mehta JL (1999) Differential Effects of a- and g-Tocopherol on Low-Density Lipoprotein Oxidation, Superoxide Activity, Platelet Aggregation and Arterial Thrombogenesis. J Am Coll Cardiol 34:1208-1215.
6. "Packer L, Valacchi G. (2002) Antioxidants and the response of skin to oxidative stress: vitamin E as a key indicator. Skin Pharmacol Appl Skin Physiol 15(5):282-90."
7. Sen CK, Khanna S, Roy S. (2004) Tocotrienol: the natural vitamin E to defend the nervous system? Ann N Y Acad Sci 1031:127-42.
8. Dial S, Eitenmiller RR. 1995. Tocopherols and tocotrienols in key foods in the U.S. diet. In: Ong ASH, Niki E, Packer L, eds. Nutrition, Lipids, Health, and Disease. Champaign, IL: AOCS Press. Pp. 327–342.
9. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000). Institute of Medicine
10. JASPREET K.C. AHUJA, JOSEPH D. GOLDMAN, and ALANNA J. MOSHFEGH. Current Status of Vitamin E Nutriture. Ann NY Acad Sci 2004 1031: 387-390.
11. Bauernfeind, J. Tocopherols in Foods. In: Vitamin E: A Comprehensive Treatise. Marcel Dekker, Inc., New York and Basel, pp. 99-167, 1980.
12. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
13. Weber, P., Bendich, A. and Machlin, L.J. Vitamin E and Human Health: Rationale for Determining Recommended Intake Levels. Nutrition 13:450-460, 1997.
14. Acuff RV et al. Am. J. Clin. Nutr. 1998;67:459-64
15. Acuff RV et al, Am. J. Clin. Nutr. 1994, 60:397-402
16. Behrens, W.A. and Madere, R. Tissue Discrimination between Dietary RRR-Alpha- and All-Rac-Alpha-Tocopherols in Rats. J. Nutr. 121:454-459, 1991.
17. Burton G et al, Am. J. Clin. Nutr. 1998,67:669-84
18. Ferslew, K.E., Acuff, R.V., Daigneault, E.A., Woolley, T.W. and Stanton, P.E. Pharmacokinetics and Bioavailability of the RRR and All Racemic Stereoisomers of Alpha-Tocopherol in Humans after Single Oral Administration. J. Clin. Pharmacol. 33:84-88, 1993.
19. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
20. Ogihara, T., Nishida, Y., Miki, M. and Mino, M. Comparative Changes in Plasma and RBC Alpha-Tocopherol after Administration of dl-Alpha-Tocopheryl Acetate and d-Alpha-Tocopherol. J. Nutr. Sci. Vitaminol. 31:169-177, 1985.
21. Traber M et al, FEBS Letters 1998,437:145-148
22. Traber MG, et al. J Lipid Res. 1990,31(4):675-85
23. Weiser, H. and Vecchi, M. Stereoisomers of Alpha-Tocopheryl Acetate. II. Biopotencies of All Eight Stereoisomers, Individually or in Mixtures, as Determined by Rat Resorption-Gestation Tests. Internat. J. Vit. Nutr. Res. 52:351-370, 1982.
24. Polidori MC, Mecocci P, Stahl W, et al. Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab Res Rev 2000;16:15–9.
25. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, and Mordan LJ. gamma-Tocopherol Detoxification of Nitrogen Dioxide: Superiority to alpha-Tocopherol. PNAS 1993; 90: 1771-1775.
26. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 Feb;81(2):508-14. PMID: 15699242
27. Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M, Miyazawa T. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317
28. Kline K, Yu w, Sander BG, et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. (1999), Nutr Cancer, 33 : pp : 26 – 32
29. The Chicago Health and Aging Project, Martha Clare Morris, Denis A Evans, Christine C Tangney, Julia L Bienias, Robert S Wilson, Neelum T Aggarwal and Paul A Scherr. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. American Journal of Clinical Nutrition, Vol. 81, No. 2, 508-514, February 2005
30. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388
31. Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem. 1992 Oct 2;35(20):3595-606. PMID: 1433170
32. Soelaiman IN, Ahmad NS, Khalid BA. Palm oil tocotrienol mixture is better than alpha-tocopherol acetate in protecting bones against free-radical induced elevation of bone-resorbing cytokines. Asia Pac J Clin Nutr. 2004 Aug;13(Suppl):

--
Get Tru-E BioComplex at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1000)

Date: December 07, 2005 10:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Green Tea Extract Fact Sheet

LIKELY USERS: People wanting antioxidant protection; Those trying to control cholesterol; People with high levels of inflammatory iron, including eaters of red meat; Those seeking to avoid caffeine, but wanting the benefits of green tea.

KEY INGREDIENT(S): Green tea extract (Camellia sinensis) 400 mg

MAIN PRODUCT FEATURES:

Total EGCg content: 50% (200 mg.) (Epigallocatechin gallate, a Catechin) Total Catechins content: 80% (by HPLC method) (Catechins are a form of Polyphenol) Total Polyphenols content: 98% (by UV method) Polyphenols, especially catechins (including EGCg), are the main active ingredients in green tea, which act as antioxidants and bind iron, which may prevent some iron-dependent inflammation.

Less than 1% caffeine content, naturally occurring (versus one cup of green tea’s roughly 40 mg. of caffeine). There should be only around 3 mg. of caffeine, per capsule.

OTHER IMPORTANT ISSUES:

• Highest dose in one capsule.
• Vegetarian form.
• One capsule contains as much EGCg as about three cups of green tea.
• Green tea may correct cholesterol imbalances by raising HDL and lowering LDL cholesterol, while preventing LDL from oxidizing. Oxidized cholesterol is a key risk factor for cardiovascular disease.
• Green tea may also be a mild anticoagulant, or “blood-thinner”.
• Green tea has been shown to help maintain levels of desirable intestinal bacteria.

  AMOUNT TO USE: One or more Vcaps® a day, preferably with meals. Three to four capsules would provide about the same antioxidant benefits as ten cups of tea, an amount used successfully in some studies.

  COMPLEMENTARY PRODUCTS: Other antioxidants including Vitamins A, C and E, selenium, alpha lipoic acid, NAC, grape seed and skin extracts, pycnogenol and pine extracts, pomegranate and various berries.

  CAUTIONS:Due to the lack of any substantial amount of caffeine in this formula, most of the usual tea cautions are not applicable. While the mild anticoagulant effects will not normally affect most people to any great degree, some caution should be used if taking blood-thinning drugs. Green tea may help the effects of chemotherapy drugs while preventing the normal tissue damage from these drugs. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=978)

  ---

  Benefits of Green Tea
  

  Date: November 05, 2005 03:30 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Benefits of Green Tea
  

  1. Cancer Prevention: The majority of research to date on Green tea focuses on cancer prevention. Population studies in Asia have found lower rates of cancer among those who consume large amounts of Green tea. (10) a Study of Japanese men and women with a 13 year follow up revealed that increased consumption of Green tea was associated with a delay of diagnosis of cancer.(1) Mean age at cancer onset among men and women who consumed over 10 cups of Green tea a day was 7.6 years later than those consuming less than three cups. It was noted that the delay in cancer was only relevant to those below the age of 79. Animal, human and test tube studies have shown that Green tea may reduce the risk of prostate, breast, esophageal, lung, skin, pancreatic and bladder cancers.(2) Of the hundreds of studies done on Green tea, only about 10% have involved humans.(10) While the data is promising, it is still limited. The good news is that this data is providing insight and direction for further studies to be done on the chemopreventive effects of Green tea.

  2. Protecting the heart: There is early evidence, though not conclusive, that regular intake of Green tea may reduce the risk of cardiovascular disease. Several well designed studies have demonstrated significant risk reduction in people who drink Green tea regularly.

  • Coronary Heart Disease - A recent cohort study assessed the effects of Green tea on 8,522 Japanese men over a period of 12 years. The data showed that men who drank 10 cups of Green tea daily versus the men who consumed only three cups daily have a lower risk of death from coronary heart disease. (3)
  • Stroke - A cohort study of Japanese women demonstrated an inverse relationship between Green tea consumption and the incidence of stroke. The study followed 5,910 Japanese women who neither smoked nor drank alcohol for four years. The incidence of stroke was significantly lower in women who consumed at least three to four cups of Green tea per day. (3)(11)
• Hypertension - In a study published in the archives of Internal Medicine, researchers concluded that consumption of Green or oolong tea at 10 ml or more per day, for one year, significantly reduced the risk of developing hypertension.(8) Researchers also examined the impact of long term tea consumption on the risk of developing hypertension in 1,507 men and women. Those who consistently drank 120 ml or more of tea per day had a lower risk of developing hypertension.

3. Exercise Endurance: People have long used Green tea for energy. A new study might shed light on Green tea as a tool for endurance. Published by American Physiological Society, the study demonstrated that Green tea extract markedly improved endurance capacity in mice.(5) Swimming time to exhaustion was evaluated in mice fed Green tea extract. The mice that were fed Green tea extract had prolonged endurance capacity by 8-24% and the effect was accompanied by a stimulation of lipid metabolism. It is also noted that the effects were dose dependent. Although not yet confirmed in human studies, these results suggest Green tea might be a useful tool for athletes.

4. Weight Loss: The newest research on Green tea has been in the area of weight loss. Research suggests Green tea promotes weight loss by favorably affecting lipid metabolism in the blood, and through the stimulation of thermogenesis (Fat-Burning).(4)(12) Regarding Green tea and thermogenesis, a study examining the benefits of functional foods for weight control showed that Green tea increased energy expenditure over a 24-hour period. This is probably due to the combination of catechins and caffeine naturally occurring in Green tea.(4) Green tea extract looks to be a promising new tool for weight loss.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=913)

---

Feds Subsidized Poor Nutrition


Date: October 29, 2005 01:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Feds Subsidized Poor Nutrition


Feds Subsidized Poor Nutrition

The U.S. Department of Agriculture (USDA) this year issued a new food pyramid aimed at convincing Americans to eat more fruits, vegetables, whole grains, and lean proteins such as dairy, meat and beans. While the USDA publicizes its pyramid with much fanfare, the agency implements policies that subsidize the consumption of nutrition-poor, high fat and processed foods, while offering no incentive to farmers to grow healthful crops.

The Pyramid versus Farm subsidies

A recent Associated Press (AP) article* contrasted the pyramid recommendations with a breakdown of this year’s $17 billion in direct subsidies to farmers.

• Corn and feed grains constitute 43% of subsidies. Critics point out that subsidized corn oil used to fry fast food burgers; thickeners and starches for processed food; and corn feed for cattle—which is unsuited for the cow’s digestive system, resulting in illness and reliance on antibiotics.
• The next most-subsidized food crop are soybeans and wheat (9% each). Soybeans are a source of hydrogenated oil that gives a flaky texture to commercial pastries, and of livestock feed, which further promotes meat consumption.
• Wheat, while a healthful grain, has become so ubiquitous in our diet that many individuals have developed sensitivities to that staple.
• Tobacco, with its well-known harmful effects, also receives 9% of farm subsidies.
• Other food crops receive less than 1% each, and fruit and vegetables receive none.

  Overproduction Leads to Lower Prices

  U.S. farm policy leads to the overproduction of nutrition-poor, fat and starch-laden foods. As a result, the prices of these foods go down, while healthy food remains less affordable.

  A related AP story describes the barriers faced by poor families who would prefer a more nutrition’s diet but end up eating cheap, unhealthy food. Adam Drewnowski, director of the University of Washington’s Center of public Health Nutrition is quoted: “Energy-dense foods rich in starch, sugar or fat are the cheapest option. As long as the healthier lean meats, fish and fresh produce are more expensive, obesity will continue to be a problem for the working poor.”

  Food Policy and the wellness Revolution

  With obesity and related health problems at a crisis point, some consumer advocates are trying to change our government’s food policies. An effective response to the current dietary crisis requires political charge as well as education about healthy lifestyles. Meanwhile, it is a wise strategy for individuals to develop a personal, nutritional supplement regimen. The centerpiece of this program should be a scientifically advanced and comprehensive multiple such as Source Naturals Life Force.

  
  
  --
  Improove your diet with a multiple at Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=905)

  ---

  Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)
  

  Date: August 02, 2005 03:52 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)
  

  Benefits

  Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine.4

  Thiamine and its Co-enzyme, TPP

  Thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically-catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name "thiamine diphosphate." In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as "active acetate." Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle (citric acid cycle). The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called "oxidative decarboxylation," and for this reason, TPP was originally referred to as "cocarboxylase." TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.

  Benfotiamine and Glucose Metabolism Benfotiamine normalizes cellular processes fueled by glucose metabolites.

  As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the Krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.5 In the presence of elevated glucose levels, the electron transport chain, the final ATP-generating system in the mitochondrion, produces larger than normal amounts of the oxygen free radical "superoxide." This excess superoxide inhibits glyceraldehyde phosphate dehydrogenase (GAPDH), as key enzyme in the conversion of glucose to pyruvic acid, resulting in an excess of intermediate metabolites known as "triosephosphates." Increase triosephophate levels trigger several cellular mechanisms that result in potential damage to vascular tissue. Cells particularly vulnerable to this biochemical dysfunction are found in the retina, kidneys and nerves.

  Benfotiamine has been shown to block three of these mechanisms: the hexosamine pathway, the diaglycerol-protein kinease C pathway and the formation of Advanced Glycation End-poducts. As discussed below, benfotiamine does this by activating transketolase, a key thiamin-dependent enzyme.6 Benfotiamine stimulates tranketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.* Transketolase diverts the excess fructose-6-phosphate and glyceraldehydes-3-phosphate, (formed by the inhibition of GAPDH, as mentioned above), into production of pentose-5-phosphates and erythrose-4-phosphate and away from the damaging pathways. Benfotiamine activates transketolase activity in bovine aortic endothelial cells incubated in glucose.6 To test benfotiamine’s ability to counteract these metabolic abnormalities caused by elevated blood glucose, studies have been done in diabetic rats. Benfotiamine increases transketolase activity in the retinas of diabetic rats, while concomitantly decreasing hexosamine pathway activity, protein kinase C activity and AGE formation.6

  Benfotiamine and Protein glycation Benfotiamine controls formation of Advanced Glycation End-products (AGEs).

  AGEs have an affinity for proteins such as collagen, the major structural protein in connective tissue. AGEs are formed through abnormal linkages between proteins and glucose. This occurs via a non-enzymatic glycosylation reaction similar to the "browning reaction" that takes place in stored food.7 At high glucose concentrations, glucose attaches to lysine, forming a Schiff base, which in turn forms "early glycosylation products." Once blood glucose levels return to normal levels, the amount of these early glycosylation products decreases, and they are not particularly harmful to most tissue proteins. On long-lived proteins such as collagen, however, early glycosylation products are chemically rearranged into the damaging Advanced Glycation End-products. AGE formation on the collagen in coronary arteries causes increased vascular permeability. This vessel "leakiness" allows for abnormal cross-linking between plasma proteins and other proteins in the vessel wall, comprising vascular function and potentially occluding the vessel lumen. A number of other potentially harmful events may also occur, including production of cytokines that further increase vascular permeability. Endothelin-1, a strong vasoconstrictor, is over produced, increasing the possibility of thrombosis and generation of oxygen free radicals is stimulated.8 It is vitally important to support normal glucose metabolic pathways so that formation of AGEs is minimized. Benfotiamine, in the test tube (in vitro) prevents AGE formation in endothelial cells cultured in high glucose by decreasing the glucose metabolites that produce AGEs.9 Endothelial cells make up the membranes that line the inner walls of organs and blood vessels. In a rat study comparing the effects of Benfotiamine with water-soluble thiamin, Benfotiamine inhibited AGE formation in diabetic rats while completely preventing formation of "glycooxidation products," which are toxic by products of chronic elevated blood glucose. AGE levels were not significantly altered by thiamin.10 Benfotiamine also normalized nerve function in the animals. After three months of administration, "nerve conduction velocity (NCV)," a measure of nerve function, was increased by both benfotiamine and thiamin; at six months, NCV was normalized by benfotiamine, whereas thiamin produced no further increases in this parameter.

  Dysfunctional glucose metabolic pathways leading to AGE formation occurs in endothelial cells of the kidneys. In a recent animal study, benfotiamine was administered to rats with elevated glucose levels. Benfotiamine increased transketolase activity in the kidney filtration system of these rats, while at the same time shifting triosephophates into the pentose pathway and preventing protein leakage.11

  Safety

  Benfotiamine has an excellent tolerability profile and can be taken for long periods without adverse effects.3,12 The statements in this fact sheet have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

  Scientific References

  1. Bitsch R, Wolf M, Möller J. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab 1991;35(2):292-6.

  2. Schreeb KH, Freudenthaler S, Vormfelde SV, et al. Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4):319-20.

  3. Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther 1996;34(2):47-50.

  4. Frank T, Bitsch R, Maiwald J, Stein G. High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. Eur J Clin Pharmacol. 2000;56(3):251-7.

  5. Pike RL, Brown ML. Nutrition, An Integrated Approach, 3rd Ed. New York:MacMillan; 1986:467.

  6. Hammes H-P, Du X, Edlestein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic neuropathy. Nat Med 2003;9(3):294-99.

  7. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci 1984;81(2):583-7.

  8. Brownlee M. The pathological implications of protein glycation. Clin Invest Med 1995;18(4):275-81.

  9. Pomero F, Molinar Min A, La Selva M, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol 2001;38(3):135-8.

  10. Stracke H, Hammes HP, Werkman D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes 2001;109(6):300-6.

  11. Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 2003;52(8):2110-20.

  12. Bergfeld R, MatsumaraT, Du X, Brownlee M. Benfotiamin prevents the consequences of hyperglycemia induced mitochondrial overproduction of reactive oxygen specifies and experimental diabetic neuropathy (Abstract) Diabetologia 2001; 44(Suppl1):A39.

  
  
  --
  Vitanet ®
  
  

  Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=721)

  ---

  Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...
  

  Date: July 27, 2005 12:28 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...
  

  Benefits

  • Supports Healthy Joint Structure and Function*

  Components of BioCell Collagen II including collagen type II, chondroitin sulfate and hyaluronic acid (HA) can enhance proteoglycans in the joint matrix, thereby providing support for healthy joint function and maintaining joint shock absorption and cushioning.

  CHONDROITIN SULFATE

  Chondroitin has been well studied for its effects on joint health. In a 1996 controlled, double-blind trial published in the Journal of Rheumatology, 146 volunteers consumed chondroitin sulfate daily for 6 months. Changes in joint function were measured according to several clinical parameters and carefully analyzed. After the first month, significant improvements were noted and maintained for three months after the subjects stopped taking the chondroitin sulfate.1 In an earlier double-blind study subjects taking chondroitin sulfate had improvements in joint function after three months of use, as determined by both objective and subjective measurements.2 In both studies, the benefits lasted for weeks after subjects stopped taking chondroitin sulfate.

  In another controlled study, 192 subjects took chondroitin sulfate or a placebo daily for one year. At the end of the trial, chondroitin sulfate maintained healthy joint cartilage thickness, while those on placebo had decreased cartilage. Improvements in joint function also occurred. The researchers reported that chondroitin exerted a clear chondroprotective effect.3

  COLLAGEN TYPE II

  A number of studies have also been conducted on the administration of collagen type II to individuals that have various joint issues. Much of this research has been conducted on animal models of joint conditions while there are also studies showing the effectiveness of oral collagen type II preparations in humans for maintenance of healthy joints.

  A randomized controlled trial conducted on 60 patients with joint health issues in 1993 found that oral administration of chicken collagen type II for 3 months led to a significant decrease in swollen and tender joints in this group, as compared to no measurable improvement in the placebo group. There were also no side effects seen with the treatment.4 A second multicenter, double-blind, placebo-controlled trial in 274 individuals with joint issues was published in 1998. The participants were given collagen type II orally for 24 weeks. Positive effects of the treatment were noted while no adverse effects were seen.5

  A paper published in 2000 reviewed the literature to assess the role of hydrolyzed collagen in joint and bone health. It was found that hydrolyzed collagen when administered orally was able to support joint health in most of the trials reviewed while the author concluded that, “Its high level of safety makes it attractive as an agent for long-term use.”6

  HYALURONIC ACID (HA)

  Most of the literature on hyaluronic acid and joint health deals with its intra-articular use, or injections of HA directly into the joints. In this realm, there is good evidence for the effects of HA on joint function.

  A study was conducted with injectable HA in individuals with TMJ (temporomandibular joint) conditions. Participants received two injections, each one week apart, or placebo injections with saline. In the HA group, the researchers found decreased clicking sounds and increased function of the joint at 1 month (90% of patients showed improvement) and 6 months (63%) of follow-up, compared to about 26% of the placebo group showing improvement at 6 months.7

  A pair of researchers also conducted a literature review of the trials using HA for improving joint health that was published in 2005. Their findings indicate a positive role for HA in modifying the structure of the joint and slowing progressive deterioration of joint function and mobility.8 Hyaluronic acid seems to have a natural affinity for joint tissue, and is therefore able to help support healthy joint structure and function.

  • SuSupports Healthy Joint Structure and Function*

  Hyaluronic Acid and Collagen are both vital components of skin tissue. Both compounds are known to decline with aging. Collagen is a vital structural component of the skin. It is also one of the most important substances required for proper skin barrier function and health. Collagen, as a major component of the connective tissue, provides structural support, increasing elasticity and tone of the skin.

  In 1994, researchers performed comparative measurements of hyaluronic acid levels in the skin of young and elderly individuals. The researchers had hypothesized that a major reason for the aged appearance of skin in the elderly is a reduction of hyaluronic acid levels. What they found using their methods is that there is a progressive reduction in the number of hyaluronic acid granules in human skin with age, until a complete absence of these granules was seen in individuals 60 years or older. These variations in HA levels with age could, according to the researchers, account for the decreased turgidity, wrinkled appearance and altered elasticity of skin tissue.9 Further research was needed to determine the effect of exogenously administered HA on the suppleness of human skin.

  In a laboratory study conducted in 1998, researchers analyzed the effects of HA given to live human skin cells. Whereas the cells on their own had a low rate of renewal, hyaluronic acid added to the cells resulted in increased proliferation of skin cells in the collagen matrix. This showed that supplementing skin cells with HA caused a significant increase in the ability of cells to go through the cell cycle.10 One of the major benefits of this may be hyaluronic acid’s ability to continually renew skin tissue to help maintain a youthful appearance of the skin.

  Safety

  Suggested Adult Use: Take 2 capsules daily, or as directed by a health care practitioner. Take with 8-10 ounces of water, with or without food.

  Scientific References

  1. Morreale P, et al. Comparison of the antiinflammatory efficacy of chondroitin sulfate and diclofenac sodium in patients with knee osteoarthritis. J Rheumatol (1996) 23:1385-91.

  2. Mazières B, et al. Chondroitin sulfate for the treatment of coxarthrosis and gonarthrosis. A prospective, multicenter, placebo-controlled, double blind trial with five months follow up. Rev. Rhum. Mal. Ostèoartic. 1992;59(7-8):466-472.

  3. Pipitone V, et al. A multicenter, triple-blind study to evaluate galactosaminoglucuronoglycan sulfate versus placebo in patients with femorotibial gonarthritis. Current Therapeutic Research 1992 52(4):608-38.

  4. Trentham DE, et al. Effects of oral administration of type II collagen on rheumatoid arthritis. Science. 1993 Sep 24; 261(5129) 1727-30.

  5. Barnett ML, et al. Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum. 1998 Feb; 41(2): 290-7.

  6. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease. Semin Arthritis Rheum. 2000 Oct;30(2):87-99.

  7. Hepguler S, et al. The efficacy of intra-articular sodium hyaluronate in patients with reducing displaced disc of the temporomandibular joint. J Oral Rehab. 2002; 29: 80-86.

  8. Goldberg VM, Buckwalter JA. Hyaluronans in the treatment of osteoarthritis of the knee: evidence for disease-modifying activity. Osteoarthritis Cartilage. 2005 Mar;13(3):216-24.

  9. Ghersetich I, et al. Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol. 1994 Feb; 33(2): 119-22.

  10. Greco RM, et al. Hyaluronic acid stimulates human fibroblast proliferation within a collagen matrix. J Cell Physiol. 1998 Dec; 177(3): 465-73.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=698)

  ---

  Best Lutein Featuring Biolut Marigold Ext., 60 VC
  

  Date: July 27, 2005 11:54 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Best Lutein Featuring Biolut Marigold Ext., 60 VC
  

  Benefits
  • Maintains Healthy Visual Function*

  It has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the course of the study, plasma levels increased five-fold from pre-supplement measures. It was also shown that macular pigment density increased by an average of 5.3% after 4 weeks due to increased deposition of lutein in optical tissues.1

  A second study compared the oral bioavailability of esterified lutein, the form in Best Lutein, versus non-esterified lutein in 18 human volunteers. Serum levels of lutein were measured at particular timepoints after consumption of a single dose of lutein. Researchers found that in these individuals, the lutein ester formulation was nearly 62% more bioavailable than non-esterified lutein, as determined by a higher mean area under the curve (AUC) and higher serum concentrations.2

  A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids may play a protective role in supporting the maintenance of healthy vision.3

  In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were divided into three groups and received either 10 mg lutein, 10 mg lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the lutein and lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group.4 These results demonstrate lutein’s beneficial effect on maintaining healthy visual function.

  • Potent Antioxidant Protection*

  Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species.5

  More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol6, demonstrating its potential as a high-powered antioxidant.

  A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems.7

  • Diverse clinical benefits*

  Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.8 Safety

  Suggested Adult Use: One capsule daily, or as directed by a health care professional. Take with or without food.

  Scientific References
  1. Berendschot TT, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Opthalmol Vis Sci. 2000 Oct; 41(11): 3322-6.

  2. Bowen PE, et al. Esterification does not impair lutein bioavailability in humans. J Nutr. 2002 December; 132: 3668-3673.

  3. Berendschot TT, et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Opthalmol. 2002 Dec; 120(12): 1732-7.

  4. Richer S, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr; 75(4): 216-230.

  5. "Lutein and Zeaxanthin". PDR Health.

  6. Chitchumroonchokchai C, et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr. 2004 Dec; 134(12): 3225-32.

  7. Krinsky NI. Possible biologic mechanisms for a protective role of xanthophylls. J Nutr. 2002; 132: 540S-542S.

  8. Mares-Perlman JA, et al. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002; 132: 518S-524S.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=696)

  ---

  The Immune System - with Kyolic Garlic
  

  Date: July 11, 2005 05:23 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: The Immune System - with Kyolic Garlic
  

  The Immune System

  The immune system is our body's natural defense system that keeps us healthy. Without it, invading organisms, which we come into contact with constantly, would cause illness and disease. There are many components of the immune system, including natural killer cells, T&B cells, macrophages and many others. Collectively, this network mainly functions against bacteria, viruses, fungi, and parasites.

  It is possible for the immune system to be suppressed. Things like stress, unhealthy habits, lack of nutrition, genetics, and other factors damage the immune system, which leaves us vulnerable to disease.

  The immune system can benefit from proper, and constant care. A healthy immune system can mean the difference between getting mildly sick versus something much worse. If you are looking for ways to boost your immune system via nutritional supplements, here are a few that might interest you:

  Aged Garlic ExtractTM (AGE): Numerous scientific studies have been conducted on AGE in relation to its effect on the immune system. Studies suggest that Aged Garlic Extract may support various immune factors,1-5 such as the ability of immune cells to engulf foreign organisms, T-lymphocyte activity,3 natural killer cell activity1,2 and antibody generation.6 Anti-fungal (Candida albicans-yeast) properties have been shown, and antiviral (herpes1,7, influenza8,9) properties have also been noted. Aged Garlic Extract has also been shown to modify, directly or indirectly, the function of immune cells, which play a leading role in allergic reactions including inflammation.10 In addition, Aged Garlic Extract has been shown to improve age-related deterioration of the immune response.

  For your convenience AGE is available as a liquid, and in a capsule, such as the Reserve, FORMULA 100 (tablet or capsule), or as the One Per Day (caplet).

  AGE also comes in combination with other herbs and nutrients that may further enhance the immune system. We have formulated a couple of products containing Aged Garlic Extract, specifically for the immune system due to the additional ingredients added that work as an extra boost in this area. Firstly, FORMULA 103 (brown/orange label) in addition to Aged Garlic Extract contains Astragalus, a potent herb demonstrating immune stimulating properties12-17 and vitamin C as Ester-C® (a unique form of Vitamin C) which may support healthy immune function.18 Another product, FORMULA 105 (pink/purple label), contains Vitamins A, C, E, selenium and green tea extract, which are very potent antioxidants. Antioxidants attack free radicals that cause damage to our body, leading to illness and aging. Please keep in mind that the various antioxidant functions attributed to AGE may also help to boost the immune system.

  Kyo-Green® is another one of our superb products. Mixing Kyo-Green in a juice or beverage may help to provide extra nutritional support since it is a source of vitamins, minerals, chlorophyll, superoxide dismutase (a very potent anti-oxidant enzyme) and other nutrients. A test tube study by Dr. Lau from Loma Linda University showed that Kyo-Green may provide nutritional support for the immune system by enhancing the activity of macrophages (immune cells that engulf foreign agents).19 Two teaspoons of Kyo-Green also provide the nutrients in a serving of vegetables so this product may function as an easy way to provide extra nutrition for the whole body.

  For those who may be interested in a more potent immune boosting formula, please try our Kyo-Green Harvest Blend The Harvest BlendTM contains all of the ingredients in the Kyo-Green, except for the kelp. However, in addition to these ingredients, other active ingredients are added to make forty-four ingredients in total, which may give the immune system a powerful kick. To help support your health there are many different greens, an immune-boosting herbal blend, antioxidant fruits and veggies, immune-enhancing mushrooms, an enzyme active sprout blend, a super energizing blend, special phytonutrients important to immune health, and a nutritious fiber blend. Please read the specifics on each of these constituents, available from the technical information available on this website.

  Finally, Kyo-Dophilus® is a probiotic supplement made of a combination of Lactobacillus acidophilus, Bifidobacteria bifidum, and Bifidobacteria longum, which help to maintain a healthy balance of the intestinal microflora and increase our first line of devense in the guy by enhancing macrophages and other immune factors by releasing immune boosting materials. This potent supplement of beneficial bacteria is also ideal for those taking antibiotics, those who are traveling or for those who just want to insure a plethora of beneficial bacteria in their intestinal tracts. Antibiotics are not selective in the bacteria that they kill off. When our friendly bacteria are wiped out, the bad guys have a window of opportunity to take over, as they grow much quicker than our friendly bacteria, and cause us problems. The lactic acid (friendly) bacteria have been shown to produce vitamins, enzymes and antimicrobial compounds that may improve the environment in the intestinal tract. Studies also suggest that friendly bacteria may help to increase resistance to some microbial infections.20-21 Kyo-Dophilus has demonstrated incredible stability at room temperature maintaining more than one billion live cells per capsule through its three-year shelf life. A minimum of one billion live cells per day is considered to be necessary to obtain desired effectiveness from a probiotic supplement. Kyo-Dophilus also comes in tablet form, in a nine-strain formation known as Kyo-Dophilus® 9, and in a smaller form for children, Kid's Kyo-Dophilus®.

  Supplying your immune system with adequate nutrition may promote health and ward of illness. If you give the body the tools it needs to heal it-self, it is amazing what it is capable of.

  References:
  
  
  1. Abdullah, T. et al. J. Oncology 21: 52-53, 1989
  2. Kandil, O. M. et al. Fed. Proc. 46(3): 441, 1987
  3. Lau et al., Mol. Biother. 3:103, 1991
  4. Lau, B. et al. Inter. Clin. Nutr. Rev. 9: 27, 1989
  
  5. Morioka, et al. Cancer Immunol. Immunother. 37: 316, 1993
  6. Yokoyama, K., Fuwa, T. et al. 1986. Oyo Yakuri (Applied Pharmacology), 31: 977-984.
  7. Tsuei, J. Method for treating genital and oral herpes. International Publication Number WO97/03203. International Patent Classification: A61K 35/78, June 4, 1987.
  8. Nagai, K. 1973a. Kansenshogaku-Zasshi (Jap. J. Infect. Disease) 47(9): 321-325.
  9. Nagai, K. 1973b. Kansenshogaku-Zasshi (Jap. J. Infect. Disease) 47(4): 111-115.
  10. Kyo, E., Itakura, Y. 1997. Phytomed. 4(4): 335-340.
  12. Chu, D.T. et al. J. Clin. Lab. Immunol. 26(4): 183?187, 1988.
  13. Chu, D.T. et al. J. Clin. Lab. Immunol. 25(3): 125?129, 1988.
  14. Chu, D.T. et al. J. Clin. Lab. Immunol. 25(3): 119?123, 1988.
  15. Wang, Y. et al. Mol Biother 4(3): 143?146, 1992.
  16. Rittenhouse, J.R. et al. J Urol 146(2): 486?490, 1991.
  17. Sun, Y. et al. Cancer 52(1): 70?73, 1983.
  18. Bendich A. Food Tech 41: 112-1124, 1987.
  19. Lau, B.H.S. 1992. Int. Clin. Nutr. Rev. 12(3): 147.
  20. Honma, N. (1986) New Medicines and Clinics 35(12): 2687-2695.
  21. Honma, N. (1974) Pediatric Clinics, 27(11): 20.
  22. Yamashita, M., et al. (1987) Clinics and Microorganisms 13(b): 87.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=569)

  ---

  Bio-Chelation
  

  Date: June 29, 2005 05:38 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Bio-Chelation
  

  Bio-Chelation* By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt In The Beginning The Bio-Chelated¨ process describes a proprietary cold extraction technique developed by Mr. Frank D'Amelio Sr., founder and owner of Nature's Answer¨, and well- respected author*. Long before Nature's Answer¨ was formed (early 1970's), Mr. D'Amelio was immersed in the study of botanical medicine, researching the various herbal texts including the national USP/N.F. (United States Pharmacopeia/National Formularies) dating back to the mid -1800's. (The USP/N.F. is a reference source that provides manufacturing standards and extraction techniques used to make herbal formulas; these standards were considered official prior to 1938.) This authoritative formulary discussed the use of plant parts such as leaf, stem, bark, flowers and roots. It recommended certain solvents known as "menstruums", in which plant parts were soaked in order to extract their active constituents. High heat was also often utilized to concentrate the extract. Mr. D'Amelio noticed that high amounts of solvents, usually alcohol, were often recommended, and that sediment would fall to the bottom (precipitate) in certain solutions. He began to investigate how he could offer the consumer potent herbal products made with very low heat, with minimum precipitation, and without a lot of alcohol!

  A Clue From Nature In working towards the goal of attaining a final botanical extract product with little alcohol, Mr. D'Amelio turned to Nature for the apparent answer. He realized that plants were composed of 80-85% water as well as some alcohols, fats, etc. If plants were able to keep the active constituents in solution and use them as needed mainly through water, not alcohol or other solvents, why couldn't he? Thus, he began a long, in-depth series of experiments with many different plants. Through rigorous research protocols and scientific testing, he discovered that the active constituents of some plants could be extracted using lower alcohol amounts with water and other natural solvents such as organic apple cider vinegar or vegetable glycerine. At other times, however, higher alcohol was necessary, such as when he was extracting volatile oils like menthol from peppermint. The experimentation process continued, with Mr. D'Amelio documenting the optimum menstruum combinations required for each plant to yield the maximum beneficial components. (Note that there are differences in alcohol. The alcohol consumed in wine and beer is derived through a natural fermentation process with no processing other than filtration. When distilled alcohol is added to an extraction, which some herbal manufacturers use, it effects the body in a more detrimental way; thus the development of the Bio-Chelation¨ process, which uses only organic alcohol).

  The Bio-Chelated¨ Method Is Developed As Mr. D'Amelio continued his experimentation with various plants and menstruums, his extraction processes became more refined, and eventually led to the development of the Bio-Chelated¨ method. The Bio-Chelated¨ method incorporates soaking for a period of time, using different menstruum ratios for different plants to optimize their therapeutic values. Furthermore, this procedure offers additional significant advantages when compared with other types of extraction processes commonly employed by competitors in the herbal industry.

  Bio-Chelation includes the use of "cold extraction", where the plant parts are extracted without being exposed to excessive amounts of heat. Cold extraction helps the herb maintain vital minerals and other trace elements in solution, thus enabling the herb to keep its Holistic Balanceª intact. (Holistic Balanceª means that extracts retain as many of the natural constituents of the original plant as possible.) In addition, the Bio-Chelated¨ process incorporates the use of an exclusive technique that removes much of the alcohol used during the menstruum soaking (maceration) phase, replacing it with vegetable glycerin instead. The resulting yield is an herbal extract that is either alcohol-free, or has a low alcohol content. (Both alcohol-free and low alcohol products from Nature's Answer feature vegetable glycerin only. Glycerin is used because it helps bind certain plant constituents, is natural to the body, is easily absorbed by the cells and has little insulin response. Only vegetable glycerin has been used since 1972. In addition, all alcohol used in Nature's Answer's low alcohol formulas is certified organic.)

  The Bio-Chelated¨ method was the first extraction process to yield a 12-14% alcohol extract in the herbal industry!

  Nature's Answer Stands The Test of Time Over the last quarter of a century (since 1972), the Bio-Chelated¨ cold extraction process has been painstakingly tested and proven to stand the test of time. Incorporating Mr. D'Amelio's proprietary cold extraction process in today's manufacturing procedures continues to yield a measurably superior product. One such example is Saw Palmetto from Nature's Answer¨, a product that is produced utilizing our Bio-Chelated¨ method versus the more expensive CO2 method. Our Bio-Chelated¨, cold extraction process yields a product that not only contains the same amounts of active constituents as the more expensive CO2 extracted product, but features a higher percentage of polyphenols, the compounds responsible for the herb's antioxidant properties. The end result is a Saw Palmetto extract that maintains its holistic balance! (Note that most prior successful studies done on Saw Palmetto utilized grain alcohol extracts which contained naturally occurring polyphenols; the CO2 extracted products do not contain polyphenols!) Although larger quantities of herbal products are now being produced as compared to the earlier experimental batches made by Frank D'Amelio, his founding corporate philosophy remains intact - combine the greatest care with the highest quality of raw material to create the ultimate herbal extract that works. After all, that's what it's all about, isn't it? Bio-Chelated¨..Another reason to count on Nature's Answer Without Question! Manufacturing Highlights:

  State-of-The-Art Laboratory Manufacturing Equipment HPLC, UV, IR, GC/MS, LC/MS, TOC and Densitometer 316 Pharmaceutical Grade Stainless Steel or Glass Lined Extraction Vessels (instead of the inexpensive, more commonly used plastic or polyethylene extraction vessels; these vessels are porous and may contain microorganisms, residual plasticizers that are difficult to clean and could cross contaminate different batches of herbs) FDA Registered & Pharmaceutically Licensed cGMP and SOP Compliant Manufactured in the U.S.A. *Botanicals - A Phytocosmetic Desk Reference (1999), Botanical & Herbal Folklore (1974), The Botanical Practitioner (1978) Bio-Chelated¨ is a registered trademark of Bio-Botanica Inc.¨ Holistic Balanceª is a trademark of Bio-Botanica Inc.¨
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=536)

  ---

  Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.
  

  Date: June 29, 2005 09:37 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.
  

  Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.

  In our high-powered world, countless Americans are searching for a wholesome, natural product to help them maintain a positive outlook and sense of well-being. The remarkable botanical, St. John’s wort, is well-known for its established history of safe use. Now Source Naturals offers you the first and only once-daily, TIMED-RELEASE ST. JOHN’S WORT. This premium botanical is manufactured in a special cellulose base, which is tested to release St. John’s wort over a 12-hour period.

  Source Naturals tests each production lot of TIMED-RELEASE ST. JOHN’SWORT. This exclusive supplement is standardized to 0.3% hypericin, yielding 2.7 mg in every convenient daily dose— the amount shown in research to support mild to moderate maintenance of a positive mood. At a time when our emotional well-being is challenged by unprecedented stress levels, research into the most convenient and effective natural remedies is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you the benefts of the latest emerging wellness strategies.

  Popular Choice For a Positive Mood—Now Even Better!

  St. John’s wort, or Hypericum perforatum, has been valued by diverse cultures as far back as the Middle Ages for its ability to support a positive outlook and sense of well-being. Today modern consumers are experiencing the benefits of this renowned herb, which include mood-brightening, relaxation, alertness, and a sense of overall well-being. Unlike other supplements on the market, Source Naturals TIMED-RELEASE ST. JOHN’SWORT is produced using the most advanced scientific methods. The result is a supplement that offers the once-daily convenience today’s consumers have come to expect.

  Clinical Trials

  A review of 23 randomized clinical trials encompassing 1757 subjects was reported in the British Medical Journal. It showed that St. John’s wort was more effective than placebo for mild to moderate maintenance of a positive mental outlook.

  The Beneficial Constituents

  The beneficial constituents of the St. John’s Wort plant are believed to be the naphthodianthrones, especially hypericin and pseudohypericin, and a wide variety of flavonoids. Source Naturals TIMED-RELEASE ST. JOHN’S WORT is standardized to consistently yield 0.3% hypericin. Each convenient once-daily dose contains 900 mg of St. John’s Wort extract, yielding 2.7 mg hypericin. This is the optimal amount found in most studies to support a positive outlook and sense of wellbeing. Benefits may be experienced within 4 to 6 weeks of initial use.

  Emotional Well-Being: Important Component of the Wellness Revolution

  Source Naturals is pleased to join with your local health food store in offering you the next generation in St. John’s wort supplementation. TIMED RELEASE ST. JOHN’SWORT can help you support a positive mood with the remarkable properties of the plant world, exclusively formulated for once-daily convenience. This advanced product reflects today’s revolution in natural health care, offering you the benefits of natural, cuttingedge supplementation.

  References
  Behnke K., Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression, Adv. Ther. 2002, Jan-Feb; 19(1): 43-52. Klaus, Linde et. al., St. John’s Wort for depression— an overview and meta-analysis of randomized clinical trials, British Medical Journal, 1996; 313:253-258 (3 August). Upton R, (ed.), et al. Monograph: St. John’s wort. American Herbal Pharmacopoeia. Special Supplement in HerbalGram. 1997;40:Sl-32. Woelk H., Comparison of St. John’s wort and imipramine for treating depression: randomized controlled trial., British Medical Journal, 2000, Sep 2; 321(7260):536-9.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=515)

  ---

  REFERENCES
  

  Date: June 25, 2005 08:13 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: REFERENCES
  

  REFERENCES

  1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=507)

  ---

  REFERENCES
  

  Date: June 25, 2005 12:40 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: REFERENCES
  

  REFERENCES

  1Penelope Od y. The Complete Medicinal Herbal. ( New Yo rk : Dorling-Kindersley, 1993) 64. 2I. Hi n d m a rch and Z. Subhan. “The Ps yc h o p h a r - m a c o l o g i c a l Effects of Ginkgo biloba Extract in Normal Healthy Volunteers.” Int. J. Clin. Pharmacol Res., (1984), 89-93. 3B. Gebner and M. Klasser. “Study of the Long-Term Action of Ginkgo biloba Extract on Vigilance and Mental Pe rformance as Determined by Means of Qu a n t i t a t i ve Pharmaco-EEG and Psychometric Measurements.” Arzneim-Forsch. (1985) 35, 1459-65. 4James Brady MD. “A Scientific Herb for Symptoms of Aging.” Doctor’s Best. (Laguna Hills, California). 5G. Vorberg. “Ginkgo biloba Extract (GBE): A Long-Term Study of Chronic Cerebral Insufficiency in Geriatric Patients.” C l i n i c a l Trials Journal. (1985) 22, 149-57. 6Michael Murray N.D., and Joseph Pizzorno, N.D. Encyclopedia of Na t u ral Medicine. ( Rocklin, California: Prima Publishing, 1991) 34. 7F. Juguet, K. Drieu and A. Piriou. “Decreased Cerebral 5-HT1A Receptors During Aging: Re versal by Ginkgo biloba Ex t r a c t , ” J . Pharm. Pharmacol. 1994 Apr. 46(4): 318-8. 8Ody, 64. 9Today’s Herbs, “Ginkgo.” (Provo, Utah: Woodland Health Books, September, 1992) 49. 10Today’s Herbs, 50. 11 F. Hoffmann, C. Beck, A. Schutz and P. Offermann. “Ginkgo Extract EGb 761 (tenobin)/HAES versus naftidr o f u ry l ( Du s o d r i l ) / Haes. A Randomized Study of Therapy of Su d d e n Deafness.” Laryngorhinootologie. 1994 March 73(3): 149-52. 1 2Rita Elkins. The Complete Home Health Ad v i s o r. ( Pl e a s a n t Grove, Utah: Woodland Books, 1994) 233. 13N. Kobayashi, R. Suzuki, C. Koide, T. Suzuki, H. Matsuda and M. Kubo. “Effect of Leaves of Ginkgo biloba on Hair Regrowth in C3H Strain Mice.” Yakugaku-zasshi. 1993 Oct. 113(10): 718-24. 14R. Kaezelmann and F. Kade. “Limitation of the Deterioration of Lipid Parameters by a St a n d a rd i zed Ga r l i c - Ginkgo Combination Product: A Multicenter Pl a c e b o - C o n t rolled Do u b l e - Blind St u d y. ” Arzneimittelforschung. 1993 Sept. 43(9): 978-81. 15A. Tamborini, and R. Taurelle. “Value of Standardized Ginkgo biloba Extract (EGb 761) in the Management of Congestive Symptoms of Premenstrual Syndrome.” Review Gynecol. Obstet. 1993 Jul-Sep 88(7-9): 447-57.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=466)

  ---

  Ginkgo: A Hair Tonic t hat Lowers Cholesterol Levels?
  

  Date: June 25, 2005 12:04 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Ginkgo: A Hair Tonic t hat Lowers Cholesterol Levels?
  

  Ginkgo: A Hair Tonic t hat Lowers Cholesterol Levels?

  Japanese experiments have recently found that the ethanolic extract found in ginkgo leaves demonstrated the ability to stimulate hair re g rowth in mice which had been given a normal and a high butter diet. Test results found that ginkgo extract not only inhibited the increase of serum triglyceride levels in the mice who ate a highly saturated diet, it also significantly promoted the growth of hair in shaved areas.13 When ginkgo is combined with garlic, a considerable drop in cholesterol levels is also observed. A number of patients with elevated cholesterol levels showed an improvement rate of 35 percent versus a control group.14 The secret to keeping cholesterol leve l s consistently low is long-term therapy with garlic and ginkgo. When the extracts were no longer taken, cholesterol levels began to rise again.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=463)

  ---

  CLA and Body Fat
  

  Date: June 22, 2005 09:50 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: CLA and Body Fat
  

  CLA and Body Fat

  Of all the health concerns facing Americans today, few are as important and daunting as weight loss and body fat. In the 1980s, Americans gained an average of eight pounds each. That’s on the order of 1 million tons of flab—2 billion total American pounds.45 So large is the current girth that as many as two in three Americans could be termed overweight.46 Being overweight and having excess fat increases the risk of heart disease, some forms of cancer and diabetes. That collection of health challenges would be difficult enough, but being overweight has many problems that accompany it, including battles with self-esteem.

  Let’s give a historical example of this story. The emotional power of being perceived as too fat is caught with pathos in the life of former U.S. President William Howard Taft. Taft, who is the only man to serve as both president and as chief justice of the Supreme Court, was noted for his honesty and his integrity. The nation mourned his death, but much of his internal story focused on his battle with weight. One editorial cartoonist showed the island of Cuba tipping under his girth. Once, when he visited Japan, an entire village worked together to pull his rickshaw up a hill. When he married, his personal esteem showed when he told his wife that “I shall worry you so much with my appetite that you must gain strength to meet the trial.”

  Taft refused to be seen on a horse because of how awkward he looked. At one point, he lost 75 pounds, but, like so many others, ended up gaining that amount back , and more, during the next 10 years. He died of athero s c l e rosis, something associated with being ove rwe i g h t .4 7 The tragedy of Taft is that, like so many suffering with weight trouble, he seemed to let it damage his self w o rth, when he was a great asset to his nation and to others. History and culture put into us that being overweight means lacking in self-control and being a glutton, when in reality this isn’t true. So many more factors are involved. Each person has a different metabolism. Certain nutrients can meet different needs, and a lack of those nutrients can lead to fat retention. CLA may be one of those nutrients, one of those factors in our diets that can change our shapes and that have nothing to do with self-control, just nutritional luck and knowledge. In a study of rats, 28 days after beginning the study, body fat in those that ate CLA was 58 percent less than in those who didn’t consume any (10.13 percent body fat versus 4.34 percent body fat, a highly significant difference). Also, the percent of muscle was about one percent more in animals that ate CLA. The weights of both sets of animals were about the same.48 (Muscle weighs more than fat. This can mean that you won’t necessarily lose weight with CLA, but would gain muscle mass, which is tighter and more shapely.) The research in this area is slightly newer, but it has been reproduced in studies on other animals.49 That more than one kind of animal has shown that body fat is lower with supplements of CLA indicates that it will likely benefit humans as well.

  In July 1997, preliminary results of one of the first human studies involving CLA showed promising, preliminary results. For three months in 1997, 20 volunteers participated in a study, daily consuming an amount of slightly more than one gram of CLA at breakfast lunch and dinner. Three months later, their weights and body-fat percents were measured. Half of the group took a placebo. The average weight of the 10 who took CLA dropped by about five pounds (not enough to be statistically significant), but the body fat percentage dropped by about 15 to 20 percent, or from 21.3 percent of average body fat to 17 percent of body fat. Meanwhile, the group taking a placebo had little or no effect on either. Half of the people in the study were men and half were women. Two people in the study decided to drop out because they received unpleasant gastrointestinal upsets. One of those who dropped out was in the placebo group, the other in the group taking CLA.63

  Nobody would suggest that CLA supplementation would be a pill freeing you to sit slug-like on the couch to watch M*A*S*H* re runs. A healthy, weight-conscious lifestyle requires many factors including exercise. As far as science can tell, CLA may not be essential the way certain vitamins are. If you consume no vitamin C, you can expect to get scurvy and die. There are no known deficiency diseases associated with an absence of CLA.

  Japanese consumers, for example, get very little CLA in their diets, but they also eat food very low in fat, and their lives are among the longest in the world.50 So, the role of CLA supplementation in regulating weight is most useful for those with a typically high-fat Western diet. As the science grows, it seems clear that CLA will lead to better health and more hope for people struggling with body fat.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=397)

  ---

  Snack Attack - we munch on about 125,000 pounds of pretzels, chips, popcorn and nuts a min
  

  Date: June 12, 2005 02:33 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Snack Attack - we munch on about 125,000 pounds of pretzels, chips, popcorn and nuts a min
  

  Snack Attack by Chrystle Fiedler Energy Times, August 5, 2003

  Americans are snackers. For instance, during the Superbowl, we munch on about 125,000 pounds of pretzels, chips, popcorn and nuts a minute; 30 million pounds by the end of the game. At work about half of us snack two or three times a day. By the end of today, as a group, we'll have eaten $22 million worth of candy-almost a million dollars an hour for every hour of every day.

  If you snack unwisely, these munchies can expand your waistline and sabotage your health. But if you snack wisely, you can keep your taste buds fulfilled, your brain working at top capacity and your body satisfied.

  When searching for snack satisfaction, think protein. Protein bars and protein shakes keep you feeling fuller longer on fewer calories than sweets.

  Second to protein, think fiber, as in fresh fruit, dried fruit, or whole grain breads and crackers.

  Unlike carbohydrates that break down into sugars and may be quickly stored as body fat, protein-rich snacks release sugar into your bloodstream at a slow, steady and healthy pace. That keeps you satisfied longer on fewer calories.

  "Protein is an important building block (for the body)," says Alicia Gonzalez, ND, a teaching fellow at Bastyr University in Kenmore, Washington. "It breaks down into amino acids as precursors to things like neurotransmitters, hormones and muscle."

  Besides eating protein-rich snacks, eat protein with every meal and eat it first. "It will help your body absorb sugar at a slower rate."

  "Protein and fiber are the best at helping the body absorb sugar at an optimal rate," says Jon Gordon, author of Become an Energy Addict (Longstreet Press).

  "Protein bars release sugar at a slower rate, resulting in more balanced blood sugar levels and greater overall energy," Gordon says. "You'll crave sugar less and will have a more sustained source of energy all day long."

  Protein Bars' Power

  "The biggest advantage of protein bars, besides their convenience, is the fact that they do have considerably more protein, say 10 grams, than candy bars, which can contain as little as 2 grams," says Dr. Gonzalez. Total fat tends to be much less in a protein bar, too.

  When choosing a protein bar, Dr. Gonzalez says, "Look for total protein content, say, between 10 and 12 grams and total fat, no more than 5 grams, and be careful with high sodium content."

  "Choose a protein bar closest to nature," says Gordon. "Like one with almonds and cashews. Nuts are full of nutrients and minerals. Nuts are also a source of fiber."

  If you exercise, protein bars with whey or soy protein make for quick replacement of necessary nutrients. "Eating a protein bar an hour before exercising helps to maintain that energy boost you need and replenishes minerals you lose when working out," says Dr. Gonzalez.

  Some protein bars, though, do a bait n' switch with saturated fats and trans fatty acids, says Dawn Weatherwax, RD, author of The Official Snack Guide for Beleaguered Sports Parents (WellCentered Books). "If the label says hydrolyzed or hydrogenated palm oil, that's as bad as saturated fat. People think they're doing the healthy thing by eating a protein bar but they end up getting the wrong type of fat."

  Besides protein bars, other healthy and healthful snacks include whole grain bread with peanut butter and cheese on whole grain, high-fiber crackers. "Mixing fiber and protein will help you sustain your energy," says Gordon. "Yogurt is also very good."

  Smooth Sailing

  "Smoothies are also wonderful (snacks)," says Weatherwax. "Add protein powder, silken tofu and fruit to them and you can have them as a meal replacement."

  "Nuts like cashews, almonds, seeds and dried berries are some of the best snacks that you can eat because you're not getting all that sugar," says Dr. Gonzalez. "Nuts have a good balance of good fat versus bad fat, including essential fatty acids, which are really important for cellular health and overall well-being. A combination of nuts, seeds and dried berries provides you with a good mix of all the vitamins and minerals along with the good fats that you need to be healthy."

  When snacking, think about variety. "Mix it up, have a protein bar one day, a protein shake the next," says Gordon. "Combine protein with a healthy carbohydrate and you'll have much more sustained energy throughout the day."

  Fuel for Your Fire

  "We're like a train, we need to keep the furnace stoked," says Weatherwax, a consulting dietitian for the Cincinnati Reds baseball team. "The goal is to eat every three or four hours. You have breakfast and lunch and you need an afternoon snack. That's the hardest one to get. Most people don't want to eat another sandwich; they want snack food. So a protein bar with a carb like a piece of fruit, an apple, orange or banana...is a great combination." "Studies show if you have moderate-size meals plus small between-meal snacks you increase your levels of energy and alertness," says Gordon. "It also optimizes your memory and performance and gives you a steady flow of energy rather than the rises and falls. Without healthy snacks your blood sugar falls and you experience fatigue and tension. Just as we need to constantly feed a fire with moderate-sized pieces of wood, we also need to continually supply our internal furnace with food that can be turned into fuel. This keeps our metabolism going strong and steady."

  "You want to stay between one-third and two-thirds full," adds Weatherwax.

  "Eating less in an effort to lose weight is actually deleterious in the long run," says Dr. Gonzalez. "When we don't eat our body gets mixed signals; it isn't sure when it's going to get its next meal. This makes the body want to store fat and sugar to save it just in case. On the other hand, if your body becomes accustomed to eating more often, the cells will be more inclined to use the fat up, knowing there is more food on the way."

  To program your body this way, don't skip meals. Have protein-filled breakfast like a protein smoothie and eggs. Follow up with healthy snacks like a protein bar or shake and regular meals.

  "Ideally, it's best to combine the macronutrients, the protein, carbs and healthy fats," says Weatherwax. "By mixing all three you actually burn more energy. One study shows that you burn an extra 35 calories."

  Nibbling on refined sweets can give you the snack blues. So let smart-snack strategies. Shift your mental outlook into high gear and use snacks wisely.

  Snacking and Exercising

  When you incorporate snacks into a consistent exercise program, you boost your chances of maintaining a healthy weight.

  To make a big difference in your day, Gordon says, get up a half an hour early to exercise. Next, eat a breakfast that includes protein and fiber, have a mid-morning snack, a healthy lunch, an afternoon snack and good dinner. Take a walk within 30 minutes of eating dinner and you'll give your body a double dose of get-up-and-go.

  "It exponentially increases your energy production and fat burning," says Gordon. Do all these things and watch your energy soar. "You'll fuel your life with real sustained power sources rather than the quick fix like coffee that's going to give you the rise in energy and then fall."

  You don't need to be told to keep on snacking. Just keep to the protein and fiber side of the snack street.

  
  
  --
  Vitanet ®
  
  

  Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=308)

  ---

  Lose the Gluten - everyone who suffers from food allergies
  

  Date: June 10, 2005 10:20 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Lose the Gluten - everyone who suffers from food allergies
  

  Lose the Gluten by Phyllis D. Light, RH Energy Times, October 14, 2004

  Are you a glutton for gluten, the sticky protein found in bagels and many other breads? Unfortunately, not everyone can enjoy the taste of fresh-baked bread because it contains this natural substance that can cause allergic reaction or intolerance in susceptible folks.

  And while not everyone who suffers from food allergies or intolerances has a problem with gluten, other foods that can cause distress include items like watermelon, fish or even the benign-seeming peanut butter and jelly sandwich.

  Still, with a little guidance, even if you have an allergy or two, you can enjoy meals and reduce food-related difficulties when you make food choices wisely.

  According to the Food and Drug Administration, more than one in 50 adults and one in 12 children in the US suffer food allergies. But the problem may be even larger. Researchers believe even more of us have food allergies and don't know it: many food allergies and intolerances may be mistaken for irritable bowel syndrome or conditions like chronic fatigue syndrome.

  Unhappy Digestion

  The involvement of the immune system in an allergy represents the dividing line between intolerance and allergy. A food allergy strikes when the immune system attacks food ingredients as though they were threatening substances. Usually, proteins trigger these physiological alarms. The most common food allergens include wheat, soy, peanuts, shellfish, eggs, fish, tree nuts, milk and watermelon. Fortunately, many children who suffer allergies outgrow them as their bodies mature.

  Signs of a food allergy may include a rash, hives, nausea, stomach pain, diarrhea, itchy skin, shortness of breath, chest pain, swelling of the airways and a condition called anaphylactic shock, a serious occurrence that can cut off breathing and requires immediate medical help.

  If you believe you have a food allergy, see your health practitioner. If you have reasons to suspect an allergy to a particular food, avoid it altogether.

  Intolerance versus Allergy

  Food intolerances are more common than allergies. They happen when food irritates the digestive system or offers substances that the digestive tract cannot break down. A food intolerance, however, does not provoke the immune system into an attack. The most common foods that cause intolerance are wheat, rye and barley; they all contain gluten.

  Figuring out an intolerance generally requires adding and eliminating foods to gauge your response. Signs can include nausea, stomach pain, gas, cramps, bloating, vomiting, heartburn, diarrhea, headaches and irritability or nervousness. If you suspect you have a food intolerance, keep a food diary-recording what you eat and how you feel afterwards.

  In addition, an elimination diet, wherein you avoid certain foods and track your responses, can help determine food intolerances. After you have dropped certain foods from your diet, reintroduce them, one at a time, until you eat a food that causes a return of your problems. These foods should then be permanently avoided.

  Inflamed Intestines

  Celiac sprue is a particularly severe inflammatory response to wheat or other grains containing gluten. According to the National Science Foundation, one in every 200 Americans suffers from this often misdiagnosed condition. That's more than a million of us!

  If left untreated, celiac sprue can cause anemia, contribute to osteoporosis by limiting calcium absorption and increase the risk for intestinal cancer. Signs include headaches, weight loss, nutritional deficiencies, fatigue and neurological symptoms. The only treatment is to avoid all grains that contain gluten.

  According to researchers in England, celiac sprue is often mistaken for chronic fatigue syndrome, type 1 diabetes or irritable bowel syndrome and can result in infertility (Med J Austral 2004 May 17; 180(10):524-6). Because sprue can confuse health practitioners, many people spend years trying to find an answer to their discomforts before finding that a gluten-free diet relieves their pain.

  According to the Celiac Sprue Association, if you have gluten intolerance you should avoid durum wheat, semolina wheat, rye, kamut, spelt, barley, triticale and often oats. Some people find they can tolerate spelt, a distant cousin to wheat that's high in fiber and contains more protein (talk to your practitioner). Oats are generally well-tolerated by most people with gluten intolerance, but because oats are often processed on the same machinery as wheat, they may have traces of gluten. If you are gluten intolerant, you can still eat rice, corn, soy, potatoes, beans, sorghum, quinoa, millet, buckwheat, arrowroot and amaranth.

  Problem Foods

  Other food ingredients can trouble digestion. They include:

• • Lactose: Up to 20% of Americans are lactose intolerant (Har Health Lett 2003 Dec; 29:6-7), reacting badly to milk products because they lack the enzyme necessary for digesting lactose (milk sugar). For these people, milk, ice cream and cheese cause gas, bloating, abdominal pain and diarrhea.
• • MSG (monosodium glutamate): A flavor enhancer, MSG can cause allergic responses in susceptible individuals.
• • Sulfites: Food preservatives-often found in baked goods, wines, snack foods and condiments-have been found to cause hives, nausea, shortness of breath, diarrhea and, in some cases, anaphylactic shock.
• • Food colorings: These items may cause allergic-type responses in some people.

  Fermented Foods

  If you have what seem to be allergies and intolerances, fermented foods that contain beneficial bacteria (probiotics) can aid the functioning of your digestive tract. Yogurt, kefir, buttermilk and sauerkraut supply active bacterial cultures and are generally easy to tolerate because they are predigested. According to researchers at Tufts University, yogurt can improve your digestive health and soothe difficulties linked to allergies and intolerances (AJCN 2004 Aug; 80(2):245-56).

  In addition, yogurt and other probiotic foods have been found to reduce the recurrence of irritable bowel flare-ups and may help reduce the risk of colon cancer. Yogurt improves gut microflora, increases bowel transit time and enhances immune response. Probiotics are also available as supplements.

  Helpful Hints

  If you have problems with certain foods or additives, becoming an amateur food detective can make meals more pleasant. Before eating a packaged food, always read the label; if you are unsure of the ingredients, contact the food manufacturer. But, in any uncertain situation, if you are in doubt of a food's ingredients, do without. Better to avoid food problems than realize too late that you've eaten a food that has upset your digestion.

  Some people find their food intolerance comes and goes, often depending upon the amount eaten and how often a food is consumed. For example, some people with lactose intolerance find they can have a little milk in their coffee or on their breakfast cereal one day a week, but have problems if they drink milk on two consecutive days.

  While deciphering which foods in your diet cause you problems can be time consuming, the reward for eliminating these nutrients, better digestion, is great. Don't give up! Persevere and, eventually your digestion will thank you.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=286)

  ---

  Allergy Alleviation
  

  Date: June 10, 2005 05:32 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Allergy Alleviation
  

  Allergy Alleviation by Cal Orey , February 2, 2002

  Allergy Alleviation By Cal Orey

  Welcome to the stuffed up world of seasonal allergic rhinitis: the wheezing, sneezing "inhalant allergies" that torment 35 million Americans. Adding insult to sinus pain, other allergens attack year-round. Air pollution, dust mites (microscopic gremlins that infest bedding, upholstery and rugs) and animal dander trigger allergies-or other respiratory ailments-in any season. Urban air is full of rubber tire particles, a true blowout for those with latex sensitivity. Altogether, roughly 50 million Americans-about one in five-suffer from some form of allergy, according to the American Academy of Allergy, Asthma and Immunology (AAAAI). Tired of cross-pollinating with plants or being bowled over by dust balls? Vitamins, herbs and other nutrients can help you nip allergy discomfort in the bud.

  The Allergy Response

  Your immune system triggers an allergic response when it overreacts to otherwise harmless substances or antigens (we're talking dust, pollen and mold).The alarmed immune system then launches a defensive chemical reaction, releasing potent chemicals (antibodies) supposed to destroy the "invaders." The antibodies, called IgE, carry the invading substances to special cells, which zap them with more biochemicals. Among these protective cells are mast cells: they release histamine, the substance that causes swelling and inflammation to the linings of the nose, sinuses and eyelids, resulting in sneezing, upper respiratory congestion and itchy, watery eyes.

  Just Blame The Folks

  Most allergies are determined by your genes. If your Mom or Dad sneeze and scratch, there's a good chance you will, too. "That is not to say that we directly inherit an allergy to any specific substance. Rather, it seems as if we might inherit some kind of immune system defect or weakness that leaves us more vulnerable to allergies," explain co-authors Glenn S. Rothfeld, MD, and Suzanne LeVert in their book Natural Medicine for Allergies: The Best Alternative Methods for Quick Relief (Rodale). For some people, allergies lurk in food, throwing the immune system into overdrive. "Many natural medicine practitioners believe that a diet high in animal fats will contribute to the development of allergy and asthma, as does a diet high in food additives, such as preservatives and dyes," says Gary McLain, PhD, in his book The Natural Way of Healing: Asthma and Allergies (Dell). Worse, allergies can up the risk of asthma, which afflicts 15 million Americans. Most people afflicted with asthma also suffer allergies: the two are linked, according to the AAAAI. Allergy triggers of asthma include pollen, mold spores and house dust mites. Remember Helen Hunt's asthmatic son in the movie As Good As It Gets? His character endured allergies to dust, and living in New York (and watching his mom date Jack Nicholson) didn't help his immune system. Coughs, ear infections, fevers and visits to hospital emergency rooms curtailed his social life (and limited his close-ups as well). That kind of routine happens in real life, too. (Well, maybe close encounters with Jack N. are not included for most.) But when we breathe substances such as molds, they can induce swelling and inflammation of the bronchial airways which narrow and restrict air flow. This, in turn, causes wheezing and shortness of breath and can trigger an asthma "attack," according to Andrew Engler, MD, who specializes in allergy and asthma in San Mateo, California.

  The Nose Knows: Chemical Sensitivities

  Imagine a picture-perfect, crisp, clear Saturday morning. You make a final stop on your weekly errand run to the dry cleaner, where you drop off your laundry and spend a moment chatting up the owner. Back in your car, your eyes tear and you feel a bit woozy. Kenneth Bock, MD, and Nellie Sabin, writing in The Road to Immunity: How To Survive and Thrive in a Toxic World (Pocket Books) sense that your reaction could be chemical sensitivity, a difficult to diagnose but, in their opinion, very real malady. (Of course, a clinician can test you for immune responses to certain chemicals.) Reactions to chemicals produce the typical allergic responses: puffy or red-rimmed eyes; swelling; aching or stiff joints and muscles; irritability or dizziness; respiratory inflammations; headaches and the like. Villains include aerosol sprays, tobacco smoke, glues, insecticides and herbicides, household chemicals and fragrances. Identification and avoidance are key, say the authors. Vitamin C, which binds with chemicals, is one of the best nutritional defenses.

  Breathing Problems Expand

  Americans now freely take lifesaving medicines such as antibiotics and insulin but, in some people, "they have the potential to alter the immune system, which is where allergies begin," says Dr. McLain. (Consult your pharmacist if you have questions about your prescription medication.) We, as a nation, are also eating more chemicals, from the pesticides drenched on plants to the preservatives poured on prepared foods. We're breathing polluted air, which can lead to or exacerbate asthma, and then we choke on recycled air in sealed buildings. And while a century ago you were likely to have spent much of your time close to home, you can now hop on a supersonic plane and be taken to the other side of the globe within a matter of hours. With travel comes exposure to even more exotic allergens that can drive your immune system to distraction.

  The All-Natural Gesundheit

  Certain allergy-relief nutrients and herbs can help make life more bearable. Here's how they work: n Vitamin C for the lungs. According to experts, when vitamin C is low, asthma is high. Vitamin C carries the major antioxidant load in the airways and therefore contributes mightily to the health of the lungs. A study in the Annals of Allergy (73(1994):89-96) reported that in seven of 11 clinical trials since 1973, vitamin C supplementation provided "significant improvements" in respiratory function and asthma symptoms. n Vitamin E and carotene to suppress allergic reactions. These antioxidants may also help protect the respiratory tract from caustic pollutants. Vitamin E is reputed to be one of the most important nutrients for antioxidant protection in the lungs. In addition, these two substances decrease production of allergy-related compounds called leukotrienes. n Zinc for the immune system. Research shows that a deficiency in this trace mineral can weaken your immune system, setting you up as a target for allergies and infections. (Some vegetarians may not store sufficient amounts of this mineral and should take supplements.) Zinc comes to the body's rescue by taking part in the production of IgA, the gastrointestinal antibody that lines the digestive tract. "When IgA binds to an allergen, it keeps it from being absorbed into the bloodstream and thus from causing an allergic reaction," report Rothfeld and Levert. Also, zinc protects mucous membranes and helps convert beta carotene to vitamin A, another anti-allergy, immune-boosting nutrient. In a study of 100 participants at the Cleveland Clinic Foundation, half took a zinc-based lozenge, while the other half received a dummy preparation. The participants taking zinc experienced a 42% reduction in the duration and severity of their common colds (Annals of Internal Medicine, 7/96). n Quercetin as an antihistamine. A valuable, anti-allergic flavonoid (plant coloring agent that is a powerful antioxidant), quercetin shines as a potent weapon against allergies and asthma. Believed to inhibit histamine release from mast cells and slow the production of other allergy-related compounds, it stabilizes mast cell membranes. Other flavonoid-rich extracts include grape seed, pine bark, green tea and Ginkgo biloba. n Additional helpful nutrients: Vitamin B-12, particularly to combat sensitivity to sulfites (The Nutrition Desk Reference [Keats]); selenium, an antioxidant that breaks down leukotrienes (Clinical Science 77, 1989: 495-500); and magnesium to relax bronchial tissues (Journal of the American Medical Association, 262 [1989]: 1210-3).

  Herbal Remedies To The Rescue

  n Nettles for hay fever relief. Research at the National College of Naturopathic Medicine in Portland, Oregon, showed that 40 of 69 folks suffering from hay fever found moderate to extreme relief from taking freeze-dried stinging nettles (Planta Medica, [1990] 44-47). "It is nontoxic, cheap and preferable to antihistamines, which I think are significantly toxic," reports Andrew Weil, MD, in his book Natural Health, Natural Medicine: A Comprehensive Manual for Wellness and Self-Care (Houghton Mifflin). n Cayenne to reduce inflammation. Cayenne, known as hot red pepper, is rich in capsaicin, a potent flavonoid "counter-irritant" that dilates and soothes inflamed nasal and bronchial tissues, according to experts. A bonus: Cayenne also contains a rich amount of antioxidant vitamin C, which can help enhance your immune system. n Echinacea for allergy prevention. This popular Native American herb provides cold and allergy protection, particularly when you take it before encountering allergens. Studies reveal that echinacea aids your body's tissues and protects you from germs and allergens. In fact, German studies have found it possesses valuable antiviral, antibacterial and immunity-boosting properties.

  Make Your World Allergy-Free

  For the most effective allergy relief, make sure you stay clear of allergens that wreak allergy havoc. Visit an allergy-savvy health practitioner and get tested to find out which substances rock your respiratory world. Plus, allergy experts recommend: n Banish dust mites: sweep out clutter and have your house power-vacuumed, if necessary; wash bedding and linens in very hot water. n De-pollinate your environment: flip on the air conditioner to sift out pollen (keep its filter and any forced air registers clean); exercise indoors; machine dry, rather than line dry, your clothes. n Buy a home air filter, especially if you experience dust, pollen or pet dander allergies. n Avoid allergy triggers that dog your days: cats and canines (or consider the hairless or shed-less breeds), mold and tobacco smoke. No matter what you do or actions you take, allergies may always remain an annoyance in your life. But attention to the foods you eat, the places where you exercise and the right combination of anti-allergy nutrients can limit your discomfort.

  Leveling The Leukotrine Playing Field

  On a microscopic level, a series of biochemicals implicated in allergic reactions are leukotrienes, substances that may constrict the bronchial tubes (breathing passages). In some people, consuming the food additive tartrazine can cause severe asthmatic breathing difficulties by boosting leukotrine release. In turn, this can interfere with the body's use of vitamin B-6. The process in which lack of B-6 or "errors" in how your body uses B-6 causes allergic reactions and is complex. According to Michael Murray, ND and Joseph Pizzorno, ND in the revised edition of the Encyclopedia of Natural Medicine (Prima), breathing problems may begin when the metabolism of tryptophan (an amino acid) goes awry: "Tryptophan is converted to serotonin, a compound that, among other things, can cause the airways of asthmatics to constrict...Vitamin B-6 is required for the proper metabolism of tryptophan." Accordingly, a study of vitamin B-6, published in the American Journal of Clinical Nutrition, shows that people with compromised breathing may possess less B-6 in their blood than others who breathe normally. When people with asthma were given B-6, their wheezing and asthmatic attacks dropped.

  Fat Fix For Allergies

  The fat in your diet or supplements can also influence your susceptibility to allergies and asthma linked to allergies. Epidemiologists have found that countries where children eat fish at least four times a month cut their risk of asthma by 67% compared to other parts of the world where they consume fewer fish. Research on omega-3 fatty acids, the kind of fat found in fish, flax and hemp oil, demonstrates that some of these substances can improve breathing. In particular, fatty acids called eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can help open up bronchial tubes. Studies in the American Review of Respiratory Disease and the International Archives of Allergy and Applied Immunology show that breathing passageways may not react so negatively to the presence of allergens when you eat more fish or take supplements containing these types of fats. Many of the scientists who study the kinds of fats we eat believe that the increase in allergies and asthma in the US during the twentieth century may be due to both increasing air pollution (which irritates our lungs) plus a simultaneous increase in our consumption of what are called omega-6 fatty acids. Omega-6 oils are contained in most of the vegetable oils Americans eat, including sunflower and peanut oils. While experts believe that we would be better off consuming a diet containing about five times as many omega-6 fatty acids as omega-3s, today we eat about 40 times as much omega-6s. The chemistry of how these fats influence our allergy susceptibility is complex. It begins in our cell membranes which consist mostly of fat. When we consume omega-3 fatty acids, in our diet or in supplements, and these fats enter cell membranes, the change in structure cuts the availability of arachidonic acid, a fatty acid your body can make and which is found in meat, eggs and dairy products. Eventually, it is thought that this change in cellular metabolism and reduction in arachidonic acid forces the body to make less 4-series leukotrienes, substances which are quite prone to provoking allergic inflammation and, instead, produce 5-series leukotrienes, leukotrienes which don't cause nearly as much trouble. This process requires patience. According to Pizzorno and Murray. "It may take as long as one year before the benefits are apparent, as it appears to take time to turn over cellular membranes in favor of the omega-3 fatty acids."

  Chinese Medicine versus Allergies

  Traditional Chinese Medicine (TCM) views allergies as an imbalance of the liver, says Jason Elias, co-author with Katherine Ketcham of The Five Elements of Self-Healing (Harmony Books). "The average American's (liver) deals with about fourteen pounds of chemicals a year. What would normally be a minor irritant becomes major because the liver can't process them anymore," explains Elias. Licorice root (Glycyrrhiza glabra) has traditionally been used to fight allergies since this herb battles inflammation as evidenced by Japanese research and a study published in the journal Allergy. Much of this anti-allergy action is thought to proceed from licorice's interaction with a biochemical called cortisol, a hormone secreted by the adrenal glands. Cortisol (along with epinephrine, another adrenal hormone) relaxes the muscles controlling airways. By slowing the liver's breakdown of cortisol, licorice prolongs circulation of this hormone which, in turn, can help breathing passages stay clear. In addition, glycyrrhetinic acid, a compound in licorice, slows the body's manufacture of prostaglandins and leukotrienes, substances which exacerbate allergic inflammatory reactions. Ma Huang (Ephedra sinica) has been employed for thousands of years to aid breathing since chemicals in this plant widen breathing passages.

  Homeopathic Remedies for Allergy

  Homeopathic treatments consist of highly diluted substances designed to coax the body into healing itself. The effectiveness of homeopathy for hayfever has been demonstrated by research published in Lancet performed at the University of Glasgow, Scotland. There, scientists showed that homeopathically-prepared medicines produced statistically significant improvements in allergy sufferers. The appropriate homeopathic remedy for any illness depends on the personality type of the person suffering an allergy. These treatments are among those recommended by Dana Ullman: n Allium cepa: appropriate for burning nasal discharge that grows worse in warm rooms and improves outdoors. Relieves non-burning tearing from eyes, raw feeling in the nose with tingling sensation and violent sneezing. n Nux vomica: used when feeling irritable and chilled, with daytime fluent nasal discharge and night congestion that grows worse indoors. Also for those sensitive to cold and to being uncovered. n Pulsatilla: best for women and children with daytime nasal discharge and night congestion who are gentle, yielding, mild, impressionable and emotional. Used when congestion is worse in warm rooms, hot weather or while lying down.

  Food Allergy Conundrum Food allergies can prove to be the toughest allergies to identify and eliminate. Jason Elias believes that people may develop food sensitivities from eating the same foods too often. "If someone has an allergy, I might say 'Let's get you off dairy for three weeks,'" he says, noting that some people have limited their hay fever problems by ceasing to consume dairy products. Many have also found relief by maintaining a food diary, keeping track of which foods are associated with allergy attacks and then eliminating those foods. So the next time you sneeze, don't just reach for your hanky, think back to the meal that you just ate. Your allergy problem may be sitting in your stomach as well as making you sneeze and stuffing your sinuses. Taking these kinds of anti-allergy preventive measures can provide life-enhancing relief that feels like a godsend. That lets you attain your healthy best.

  This article included reporting by Judy Pokras.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=278)

  ---

  Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
  

  Date: May 24, 2005 09:52 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
  

  Cognitive Improvement in Mild to Moderate Alzheimer's Dementia After Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Maria De Jesus Moreno Moreno, MD Instituto Nacional de la Senectud, Mexico City, Mexico

  
  This study assessed the efficacy and tolerability of the cholinergic precursor choline alfoscerate (CA) in the treatment of cognitive impairment due to mild to moderate AD (Alzheimer's disease).

  in both men and woman they consistently improved after 90 and 180 days versus baseline with adiministration of GPC three times a day, whereas in the placebo group they remained unchanged or worsened. Statistically significant differences were observed between treatments after 90 and 180 days.

  Keypoints:

• improved cognition and global function
• showed a statistically significant improvement after 90 and 180 days of treatment
• Increased neurotransmission
• With out treatment men and woman declined consistantly

• references:

  Bartus RT, Dean RL III, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction, Science. 1982;217:408-414. 2. Larson EB, Kukull WA, Katzman RL. Cognitive impairment: Dementia and Alzheimer's disease. Annu Rev Public Health. 1992;13:431-449. 3. Hofman A, Rocca WA, Brayne C, et al, for the European Prevalence Research Group. The prevalence of dementia in Europe: A collaborative study of 1980-1990 findings. Int d Epidemiol. 1991;20:736-748. 4. Blackwood W, Corsellis JAN, eds. Greenfield's Neuropathology. 3rd ed. London: Arnold; 1976. 5. Geldmacher DS. Cost-effective recognition and diagnosis of dementia. 5emin Neurol. 2002;22:63-70. 6. Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459. 7. Perry EK. The cholinergic hypothesis--ten years on. Br Med Bull. 1986;42:63-69. 8. Giacobini E. From molecular structure to Alzheimer therapy. Jpn d Pharmacol. 1997;74:225-241. 9. Giacobini E. Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: From tacrine to future applications. Neurochem Int. 1998;32:413-419. 10. Brinkman SD, Smith RC, Meyer JS, et al. Lecithin and memory training in suspected Alzheimer's disease. J Gerontol. 1982;37:4-9. 11. Davis E, Emmerling MR, Jaen JC, et al. Therapeutic intervention in dementia. Crit Rev Neurobiol. 1993;7:41-83. 12. Amenta E Parnetti L, Gallai V, Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropiate approaches? Mech Ageing Dev. 2001;122:2025-2040. 13. Sigala S, Imperato A, Rizzonelli P, et al. k-Alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eurd Pharmacol. 1992;211:351-358. 14. Govoni S, Battaini E Lucchi L, et al. Effects of alpha-glycerylphosphorylcholine in counteracting drug-induced amnesia: Through cholinergic and non-cholinergic mechanisms [in Italian]. Basi Raz Ter. 1991;21:75-78. 15. Canonico PL, Nicoletti F, Scapagnini U. Neurochemical and behavioral effects of alpha-glycerylphosphorylcholine [in Italian]. Basi Raz Te~ 1990;20: 53-54. 191 CLINICAL THERAPEUTICS ® 16. Parnetti L, Amenta E Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: An analysis of published clinical data. Mech Ageing Dev. 2001;122:2041-2055. 17. Venn RD. The Sandoz Clinical Assessment-Geriatric (SCAG) scale. A general-purpose psychogeriatric rating scale. Gerontology. 1983;29:185-198. 18. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991;19:330-341. 19. Frattola L, Piolti R, Bassi S, et al. Multicenter clinical comparison of the effects of choline alphoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia. Curt Ther Res Clin Exp. 1991;49:683-693. 20. Muratorio A, Bonuccelli U, Nuti A, et al. A neurotropic approach to the treatment of multi-infarct dementia using L-c~-glycerylphosphorylcholine. Curt Ther Res Clin Exp. 1992;52:741-75l. 21. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: APA; 1994. 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. 23. Folstein ME Folstein SE. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198. 24. Loeb C, Gandolfo C. Diagnostic evaluation of degenerative and vascular dementia. Stroke. 1983;14:399-401. 25. Hamilton M. A rating scale for depression.J Neurol Neurosurg Psychiatry. 1960;23:56-62. 26. Hamilton M. Development of a rating scale for primary depressive illness. BrJ Soc Clin Psych& 1967;6:278-296. 27. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. AmJ Psychiatry. 1984;141:1356-1364. 28. Reisberg B, Ferris SH, De Leon MJ, et al. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry. 1982;139:1136-1139. 29. National Institute of Mental Health. Clinical global impressions. In: Guy W, ed. ECDEU Assessment for Psychopharmacology. Revised edition. Rockville, Md: National Institute of Mental Health; 1976:217-222. 30. Burns A, Russell E, Page S. New drugs for Alzheimer's disease. Br J Psychiatry. 1999;174:476-479. 31. Kumar V, Anand R, Messina J, et al. An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors. Eur J Neurol. 2000;7:159-169. 32. Knapp MJ, Knopman DS, Solomon PR, et al, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991. 192 M. Moreno 33. Lindstrom MJ, Bates DM. Newton-Rapshon algorithms for linear-mixed effects models for repeated measure data. J Am Stat Assoc. 1998;83:1014-1022. 34. Thai LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology 1996;47:705-711. 35. Rogers SL, Friedhoff LT, for the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303. 36. Rogers SL, Doody RS, Mohs RC, Friedhoff LT, for the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158:1021-1031. 37. Corey-Bloom J, Anand R, Veach J, for the ENA 713 B352 Study Group. A randomized trial evaluating the efficacy and the safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1:55-65. 38. Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. BMJ. 1999;318: 633-638. 39. Amenta E Bronzetti E, Del Valle M, Vega JA. Effects of alpha-glycerylphosphorylcholine in neuroanatomy of aging brain in experimental animals [in Italian]. Basi Raz Te~: 1990;20:31-38. Address correspondence to: Scientific Department, Italfarmaco SpA, via dei Lavoratori 54, 20092 Cinisello Balsamo, Milan, Italy.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=98)