Date: June 17, 2008 06:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Echinacea Purpurea Root

There are nine known species of Echinacea native to the United States and southern Canada. The most commonly used and most potent of them is Echinacea purpurea.

Other common names for Echinacea are purple coneflower, American coneflower and coneflower. The plants contain large heads of flowers that bloom in early to late summer.

In North America, Native Americans used Echinacea more than any other herb for its healing properties. For Europeans and Americans, it was believed to aid in curing Anthrax and snakebites as well as contain antimicrobial properties.

Echinacea is well known for its abilities to boost the immune system and to help fight infections. It is also widely used to prevent infections, colds and the flu. In lesser known medicinal practices, it is used to treat wounds and such skin problems as acne and boils. Some studies have shown that Echinacea has been effective in treating upper respiratory infections.

The whole Echinacea plant is used for treating various indications. Fresh or dried, the plant and roots are used to make teas, extracts, juices or external salves, creams and ointments. As a general rule, the fresh-pressed juice of the Echinacea plant is most effective in treating colds in children. In adults, both the root and herb in combination are most effective.

When taken at the first signs of a cold, Echinacea has been found to reduce the length and severity of cold symptoms. Be aware that Echinacea is not a one-dose fix-it remedy. Begin taking recommended doses at the first signs of a cold. Subsequent doses should be taken regularly, according to the product label, until all symptoms have disappeared.

Unfortunately, many herbal preparations can vary in effectiveness due to a lack of systematic extraction and refining. It is best to research the manufacturers of herbal products to find out how they cultivate and store their herbs. Their methods will cause the chemical compositions to vary greatly. The different parts of the plant that are used vary widely in their chemical makeup as well. One part may be extremely useful as an antimicrobial, while another may stimulate stronger reactions from the immune system. Other factors that may affect the quality of the product you purchase are:

* Species * Plant part * Extraction method * Contamination * Adulteration

Side Effects and Warnings:

When taken orally (by mouth), Echinacea usually does not produce any side effects. In rare cases, some people have experienced allergic reactions and side effects that include:

* Rashes or dermatitis * Pruritus (itching) * An increase in asthma symptoms * Anaphylaxis (life threatening allergic reaction) * Hepatoxicity * Nausea * Dizziness * Dyspnea (difficulty breathing)

All of these symptoms tend to be mild and infrequent. If you suffer from asthma symptoms, you should probably avoid using echinacea. In most cases the most common side effects are gastrointestinal in nature, such as gas or mild cramping. People are much more likely to experience side effects if they are allergic to other plants in the daisy family. These plants include:

* Ragweed * Chrysanthemums * Marigolds * Daisies

Use of Echinacea in children younger than 12 years is not recommended due to lack of sufficient data to support safety. It is also not recommended for use in pregnant or nursing women.

Echinacea should not be used if you have progressive systematic or auto-immune disorders, connective tissue disorders or other diseases that may be related to these. It should not be taken if you are taking immune-suppressants and heap-toxic drugs. It may also interfere with anesthesia.

It is important to communicate with your health care providers. Be sure they are aware of any alternative herbs or other substances you are using and what their purpose is in your daily diet.

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Date: June 10, 2008 11:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants For The Body

Eating the fruits and vegetables that naturally contain antioxidants is the best way to get them into your system. Mixing them into a well-balanced and healthy diet is the best method of all. This way you reap the benefits of all of the antioxidants in a natural combination.

The benefit of dietary antioxidants is that they slow the chemical process of oxidation. This oxidation is what causes narrowing of the arteries and heart-related health problems due to cholesterol deposits. Eating a regular variety of herbs, vegetables and fruits that contain antioxidants is the best way to maintain good health. Some foods that contain antioxidants include:

* Tomatoes
* Garlic
* Onions
* Rosemary
* Grapes
* Pomegranates

Antioxidant supplements are available, lab testing have shown that they are just as effective as their natural counterparts. Natural foods contain ranges of antioxidants that work together synergistically. These combinations of antioxidants are much more effective.

More Benefits:

Antioxidants and other nutrients are needed by the body to protect against cell damage. They also may reduce the risks of certain forms of cancer.

It has been discovered that the mitochondria (cell power plants) are a major source of oxidant production. They are also a target for the damaging effects of the very oxidants that they produce. This is a major cause in the advancement of cellular aging, called apoptosis.

It is believed that in apoptosis, each cell has a fixed number of cell divisions that it is capable of. After the cell has used its allotted number of divisions, it ceases to function. Oxidative damage is also a contributing factor of DNA mutation, which causes further malfunction of the cells.

Most Common Antioxidants:

The following is a list of the most common antioxidants, what benefits they offer and where to find them:

*Beta-carotene keeps the skin healthy and promotes growth and development of bones. It also helps to prevent night blindness and fight infection. Beta-carotene is found in vegetables and fruits: carrots, cantaloupe, apricots, broccoli, peppers, tomatoes, spinach, sweet potatoes and pumpkin.

* Vitamin C destroys free radicals inside and outside cells. It helps in the healing of wounds, preventing bruising, formation of connective tissue, iron absorption and keeping gums healthy. Vitamin C is being studied for its beneficial effects in reducing cataracts, cancer and heart disease. Foods high in vitamin C include tomatoes, citrus fruits and juices, berries, mango, papaya, peppers, cabbage, spinach, broccoli and potatoes.

* Vitamin E acts as the essential fat protector in cell membranes and red blood cells. It reduces the risk of heart disease, cancer and other diseases associated with age. Vitamin E is found in peanut butter, nuts, seeds, vegetable oils, margarine, whole grains, wheat germ, salad dressings and avocado.

* Selenium helps the body maintain healthy hair and nails. It also enhances immunity and, along with Vitamin E, prevents cell damage. Vitamin E reduces the risk of cancers, especially prostate, lung and colorectal. The best sources of Selenium include brazil nuts, garlic, meat, eggs, poultry, seeds, seafood and whole grains. The amount of selenium found in plants depends on the soil content in which they are grown.

Antioxidants benefit the body by providing a layer of protection for the tissues and cells. They are the front line of the body's protection against free radicals. Free radicals are unstable by-products of oxygen that cause premature aging and degenerative diseases. They also come from environmental sources, such as pollution, UV rays and other toxins. Foods rich in antioxidants help to clean free radicals from the body. They also help to prevent various age-related diseases, cancers and heart disease.

Maintaining a healthy, nutritionally balanced body that has the ability to fight disease and infection is a prime way to live a long, disease free and happy life. Regular ingestion of antioxidant rich foods or supplements is the best method to achieve this.

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Date: May 08, 2008 03:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cetyl Myristoleate

Cetyl myristoleate is a fatty acid ester used largely as a dietary supplement to support joint mobility and the immune system. Chemically it is a natural hexadecyl ester of cis-9-tetradecanoic acid, an unsaturated fatty acid commonly known as myristoleic acid.

The acid is found naturally in fish and whale oils, and also in butter and kombo butter from the kombo nut. The ester is of a buttery consistency at normal room temperatures, and turns waxy when cooled, and it has no known uses other than as a health supplement, particularly for the treatment of arthritis and other inflammatory and immune system problems.

The substances appear to have similar therapeutic characteristics to unsaturated essential fatty acids, but with a stronger and more long lasting effect. It also appears to work in three distinctly different ways in that it acts as a joint lubricant, supports the immune system and functions in the same way as essential fatty acids.

Arthritis is a disease that has reached epidemic proportions worldwide, and it is estimated that more than 50 million Americans are affected by it. Until recently it was believed to be a disease of the aged, or associated with physical injury, but is now known to be more complex than that, with many manifestations and causes. Because of this, no single treatment is effective with all forms of arthritis, but cetyl myristoleate is the new kid on the block that is believe to make a significant contribution to the treatment of non-infective forms of the disease.

However, it was not always known, and a search in the textbooks for cetyl myristoleate prior to 1977 would have yielded nothing. Why 1977? It started with Harry W Diehl, a sugar chemist with an interest in the treatment of arthritis. While carrying out research on arthritis in mice, he was working on thin layer chromatographic analysis of a methylene chloride extract of macerated mice. He noticed a separation that was unknown to him, which was subsequently identified as cetyl myristoleate.

He had been unable to induce arthritis in mice, and believed that if he found out how to do that, then he should also be able to establish what made the mice immune to the disease, and so establish a cure. He soon established that it was this cetyl myristoleate circulating in the blood that protected the mice, and then found a way of synthesizing it in the lab by esterifying myristoleic acid.

Since the compound was unknown at that time Diehl patented it in 1977, hence the date. Apart from in mice, it has subsequently been found only in whale oil and in one of the glands of the male beaver, with no other known sources at the time of writing. There have been several studies that have supported the effect of cetyl myristoleate on arthritis, the first human study being in 1995 when 46 out of 48 arthritis patients showed significant improvement in articular mobility and reduction in pain. Others since have demonstrated similar results.

So how does it work? What is the mechanism by which this hitherto unknown substance helps to relieve the symptoms of osteo and rheumatoid arthritis? Being a fatty acid ester, cetyl myristoleate possesses lubricant properties, and one of its properties is to supplement the synovial fluid that lubricates the joints and tendons. This helps to keep the joints moving freely, and reduces their tendency to grind when the connective tissue wears. It also lubricates entire muscle groups, allowing them to slide over each other more freely, and also over bones allowing a smoother movement of the joints.

The second way, in which it operates, by supporting the immune system, is particularly appropriate to the treatment of rheumatoid arthritis which is caused by the immune system attacking the body’s own joint and connective tissue. In this respect, cetyl myristoleate has also been found effective in treating other immune system conditions such as multiple sclerosis and lupus erythematosus.

Finally, it also possesses the mediation effect on the inflammatory reaction possessed by other essential fatty acids. This helps to reduce the effect of inflammation that causes much of the swelling and pain of arthritic conditions, although it occurs much faster than with other fatty acids. When taken together, all of these effects have a powerful effect in reducing the unpleasant symptoms of both osteoarthritis and rheumatoid arthritis. Swelling is reduced, mobility is improved and pain is alleviated. Improvements have been reported by sufferers of both types of arthritis, and in fact it is reported that Harry Diehl successfully treated his own arthritis with the substance before any other human tests had been carried out.

Cetyl Myristoleate is now used word-wide in significant quantities, and there have as yet been no confirmed reports of adverse side effects. However, as with many otherwise safe supplements, it is recommended not to be taken by pregnant or lactating women until it has been proved to definitely have no side effects on the fetus or young babies.

Although there is no definitive scientific evidence of the effectiveness of the substance in relieving the symptoms of arthritis, there is an overwhelming body of evidence from those that have used it world wide. The accepted treatment is by non-steroidal anti-inflammatory drugs (NSAIDs), and with over 16,0000 NSAID-related deaths in the USA alone each year, cetyl myristoleate is certainly worth considering as an alternative for arthritis sufferers. Not only that but there is a very significant price differential, with NSAIDs costing 5 – 10 times that of cetyl myristoleate.

Among the other benefits that people using the substance have reported are beneficial effects on psoriasis, hepatitis, high blood pressure, eczema, allergies, headaches and many more. Although many of these might be coincidence or psychosomatic, it cannot just be coincidence that many of them, such as psoriasis and allergies, are related to the immune system.

However, anybody with asthma or a history of severe allergic reactions should consult their physician before using the substance. That aside, there is more than enough popular evidence to indicate that cetyl myristoleate is effective in the treatment of arthritis in all its forms, and also good for your general state of health and wellness.

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Date: April 30, 2008 03:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Shark Cartilage

Sharks do not have skeleton of bone but of cartilage, which is a dense form of connective tissue. Its main components are cells known as chondrocytes that are responsible for producing collagen fibers, an elastic protein called elastin that is responsible for the skin returning to its original shape after being pinched, and ground substance that is rich in proteoglycan, a protein with glycosaminoglycan chains.

Shark cartilage is said to be beneficial in the treatment of many conditions including arthritis, psoriasis (allied to arthritis), rheumatism, eczema, acne, allergies and the most controversial – cancer. It is said to inhibit tumor growth by inhibiting angiogenesis – the formation of new blood vessels by growing them from old ones. This can lead to metastasis, or the spread of cancer between organs and also feed the cancer cells with blood.

Shark cartilage has been used medicinally for thousands of years, particularly in ancient China where its use is documented, and might also have been in other areas where the consumption of fish was high. However, the production of shark cartilage and its trade is not well documented. The major cartilage consuming countries are Australia, India, Japan and the USA, although it is used or consumed in many other countries, especially Hong Kong, Taiwan, China and, increasingly, Europe.

The best quality of cartilage is from the blue shark due to its higher chondroitin quality. Chemically, chondroitin is an acid mucopolysaccharide, and a very large molecule that is used for a variety of purposes. In arthritis it is difficult to get it to the source of the problem due to its physical size and large doses are used to ensure that at least a proportion passes through the capillaries to the joints.

Arthritis is a particularly prevalent disease and comes in two forms: osteo- and rheumatoid arthritis. Osteoarthritis develops over a long period of time, and generally the cartilage roughens and becomes thin, while the bone becomes thinner. Extra synovial fluid, that lubricates the joint, can be formed and that causes swelling. The bone tried to repair itself, but degeneration continues and the tendons become affected. Eventually inflammation can occur leading to severe swelling and pain. There are several causes, the most common being injury or repetitive hard use of the joints.

Rheumatoid arthritis, on the other hand, is completely different, and is caused by the immune system rather than wear and tear. The immune system mistakes parts of your joints as being foreign, and attacks the synovial membrane, or lining of the joint. It might also attack the sheath around the tendons. This eventually causes the cartilage to thin and the joints to wear, and the inflammatory response can cause painful inflammations. There is no apparent cause, though heredity, lifestyle and hormones might all be connected.

The effect of shark cartilage on arthritis is well documented, and in one study in the 1970s, only 11% of patients did not respond well to a treatment of cartilage injections. The pain relief the injections provided lasted from six weeks to over a year, though no reason could be provided for the vast difference. However, it did seem to demonstrate that the remedy was more than just a placebo. In another study involving bedridden osteoarthritis patients, eight out of ten could leave their beds after only three weeks of oral cartilage treatment. Shark cartilage appears to be effective when administered both intravenously and orally.

In a later placebo study involving 147 arthritis patients, they were given either shark cartilage or a placebo. Those with the placebo were encouraged to use other treatments when their pain became severe. After five years the placebo group reported a 5% drop in pain scores compared to 85% of the group taking shark cartilage. The joint deterioration in each group was assessed, and was considerably less in the cartilage group, who also lost less time at work through pain.

All of these results indicate that shark cartilage can be used to relieve osteo- and rheumatoid arthritis pain in at least 60% of sufferers. Since rheumatoid arthritis has been linked to psoriasis, this could also explain its effects on psoriasis. What the studies did indicate is that you need not wait five years to find if the treatment is effective or not: if you do not experience positive results within between four and six weeks, then shark cartilage treatment will likely not work for you.

There is no doubt that shark cartilage can provide relief to painful, swollen joints, and this is likely due to the mucopolysaccharides. It can also prevent the undesirable growth of new blood vessels into the cartilage and appears to help to regulate the immune system. These are also two of the reasons why it is believed by some to be an effective treatment for cancer by preventing metastasis.

It was the publication of the book “Sharks Don’t get Cancer” that started the rush for shark cartilage as a a treatment for cancer, but the problem is that sharks do get cancer – they even get cancer of the cartilage! However, that does not mean that the scientific reasons for the inhibition of metastsis are invalid. They are valid, and it is metastsis rather than the original cancer that ferquently leads to death. Metastsis is the spread of the disease round the body by the bloodstream, and shark cartilage appears to be able to help to prevent that. It also prevents the growth of blood cells into cancerous areas to feed the cancers with oxygen and other nutrients.

Although there are few reported side effects of shark cartilage, in the interest of safety it is advised that children and pregnant women should avoid it. The same is true of people recovering from recent surgery since it could slow healing due to its effect on repairing blood vessels. If you have a low white blood cell count, do not have a shark cartilage enema since it can cause a potentially fatal infection.

Otherwise it should be safe to take, and is available in many forms including creams, capsules, powders and injections. The recommended dosage is 1 gram dried shark cartilage for each 7 Kg (15 lb) body weight. Once you begin to see an effect on the pain of your arthritis, one can then try to reduce the dose to 1 gram for each 18 Kg (40 lb) body weight.

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Date: April 28, 2008 02:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cherry Fruit Extract

Cherry fruit extract contains organic compounds known as flavanoids, which is a form of phytochemical frequently found in highly colored fruits and vegetables. If you eat a fruit such as pomegranate, blueberry, blackberry or cherry, or if you eat red peppers, aubergines and broccoli, you are eating foods that are rich in flavanoids.

Such foods provide you with remarkable health benefits that your ancestors knew about but did not understand. They ate these highly colored foods because they knew they helped prevent certain medical conditions, and to help others get well faster. They knew nothing about phytochemicals – chemicals contained in plants – or flavanoids, but knew about the results of eating them.

In fact, flavanoids are very powerful antioxidants and anti-inflammatories, and each of these require more detailed explanation since between them, oxidants and inflammation are responsible for most of the non-infectious common ailments of the human body. First, let’s have a look at antioxidants.

In chemical terms oxidation is the removal of an electron from an atom or molecule. There are species within your body known as free radicals whose sole purpose in their short life is to steal an electron from the nearest molecule to them. This is almost instantaneous, and most free radicals are very short lived. The concept of free radicals roaming your body and your bloodstream waiting to pounce on the first unwary molecule is a fairy tale. In fact the vast majority react as soon as they are formed.

When they do react, they remove an electron from a stable molecule, render it unstable and thus destroy it. If that molecule is part of a cell, and enough of them are robbed of their electrons, then the cell is destroyed. One result in visible terms is wrinkling of your skin, as your skin cells become destroyed, and hence you age quicker. In terms that you are not immediately aware of, oxidation can lead to many unwanted changes in your body.

For example, the low density lipids, that carry the cholesterol in your blood to areas of the body where it is needed, are oxidized by free radicals which causes the LDL to deposit along with their cholesterol on the walls of your arteries as a layer of plaque. Eventually that will build up to constrict the artery and cause a condition known as atherosclerosis – the arteries become blocked, and you can suffer from heart attacks and strokes.

These free radicals are formed by the normal metabolism of the body when energy is created in the cell mitochondria, by pollutants such as pesticides, cigarette smoke and traffic fumes, and by radiation such as excessive exposure to the UV radiation in sunlight.

Flavanoids, contained in cherry fruit extract, are antioxidants, which prevent this oxidation of body cells from taking place. They do so by being in the right place at the right time. If a flavanoid molecule is close to a free radical when it is generated, then the antioxidant will reduce the free radical and neutralize it.

If you eat a lot of cherries, or drink cherry fruit extract, you will be consuming a massive amount of flavanoids molecules that are ready and willing to destroy these free radicals. However, that is not all that flavanoids do. They are also, as has already been stated, anti-inflammatories.

The inflammatory response is the reaction of the body to a foreign presence such as bacteria. The tissues around the infected area receive an increased blood supply, and the cell walls produce gaps allowing the large immune system blood cells, or macrophages, to pass through. The temperature around the area increases due to the concentration of blood, and this itself is controlled by the body since bacteria die off after a certain body temperature has been reached, hence the reason for fever in the immune response.

The area swells up due to the concentration of fluid and protein, and becomes painful due to pressure on nerve endings. Anti-inflammatories, such as the flavanoids, work to relieve the symptoms of inflammation without interfering with the way the immune system deals with infection.

Many inflammatory conditions occur without any apparent reason, and while anti-inflammatories might not be used to suppress the immune system, it is used in such conditions as rheumatoid arthritis where the inflammation is a mis-firing of the immune system. Cherry fruit extract can be used to alleviate many similar conditions such as gout, and osteoarthritis where its use is well known and recorded.

It can also be used to help reduce the effects of atherosclerosis through its anti-oxidant properties, and cherries contain, not only a good supply of flavanoids, but also anthocyanins, another group of powerful antioxidants. They also contain vitamin C which is also a strong antioxidant.

Another property of flavanoids is their collagen strengthening properties, which they achieve by cross-linking the fibers to form a string fibrous network. That can be used to strengthen the walls of veins, and render them less liable to stretch or expand, thus providing them with the rigidity needed to prevent varicose veins caused by the puddling of blood below weak valves. They have the same effect on arteries, providing increased strength and a reduction in the blood pressure needed to pump blood round the body.

A good intake of cherry fruit in your diet will help to improve the condition of your cartilage and other connective tissue in addition to your veins and arteries, and is particularly appropriate for athletes who place great stresses on connective tissues such as the tendons that transfer muscular energy to the levers – the long bones.

In summary, then, cherry fruit extract and the flavanoids and anthocyanins it contains, posses properties to help relieve the symptoms of gout, and various forms of arthritis, to reduce the likelihood of cholesterol oxidation that leads to heart disease and strokes, to help strengthen the walls of veins and arteries and to improve the strength of connective tissue such as cartilage and tendons.

In other words, to improve the quality of life of the majority of the population that suffers from one or more of these conditions. After learning about the health benefits of cherries and all the mounting evidence in research, my question to you is why did the FDA make cherry farmers pull the health benefits of cherries from their websites with threats of legal action if not removed? Makes a person wonder who is on our side and who isn’t?

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Date: April 12, 2008 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins

Bilberry extract is taken from the Vaccinium myrtillus, or bilberry, a small blue berry that has been used traditionally for the treatment of conditions now known to be due to inflammation and the action of free radicals on the body.

Among these is atherosclerosis, or hardening of the arteries, caused by the free radical oxidation of the low density lipids that carry cholesterol around the bloodstream, and that cause deposition of fatty plaques on the arterial walls and eventually constricts them to a stage that can cause heart failure or a stroke, depending on whether the arteries are close to the heart or in the brain.

However, additional to treating this condition, bilberry has also traditionally been used for the treatment of varicose veins and also for certain eye conditions. In fact it was during the Second World war that the Royal Air Force in Britain received reports from pilots that their night vision improved after eating bilberries. Not only their vision, but the restoration of night vision after exposure to glare.

This was extremely important to war-time pilots who had to be able to rapidly adapt their vision to fly their plane after exposure to searchlights and explosive detonations. That is the reason for anything that appeared to promote this essential adaptation to be reported.

The pharmacology of these effects have been found to be due to the anthocyanosides in which bilberries are particularly rich. Anthocyanosides consist of an anthocyanaidin backbone, to which one of either arabinose, galactose or glucose can be bound. Since bilberry contains five of these anthocyanadins, then there are fifteen different anthocyanosides in the fruit concentrate.

The area of the retina that appears to control night vision, and the transition from day to night sight, is called the epithelium which is connected with purple vision. Anthocyanosides seem to have an affinity for this part of the retina, and in so doing plays an important part in this type of vision, specifically night vision although it is also beneficial in improving day vision.

Although bilberry also contains vitamins A and C, hydroquinone and tannins, it is the anthocyanosides that provide it with its unique antioxidant properties, and also its effect upon collagen fibers. It can cross-link collagen fibers to help overcome weaknesses in the connective tissues such as cartilage, tendons and the walls of blood vessels.

Its effect as an antioxidant is to prevent the cleavage of collagen by the cyzymes that are secreted by leukocytes generated by the immune system. By preventing histamine release, and release of prostaglandins and other proteins and cells mobilized during the immune inflammatory response to the detection of foreign invasion into human tissue, anthocyanosides can help to reduce inflammation and to protect against other extreme reactions of the immune system that can harm the organism it evolved to protect.

The most powerful property of anthocyanosides are their antioxidant properties: perhaps even its only property once all of the conditions it helps to protect against are fully understood. An antioxidant combines with free radicals and destroys them. Free radicals are particularly vile chemical entities that require an electron to make them stable, and they take this electron from the nearest source. This can result in oxidation and destruction of many bodily tissues leading to premature aging, atherosclerosis, eye damage and many other problems that result from the destruction of body cells and tissue.

The various constituents that make up bilberry act in concert to scavenge the free radicals and increase the supply of oxygen to the eye. The benefits of this are in helping to prevent cataracts and glaucoma, the latter due to the effect of the anthocyanoside cross-linking effect on the structure of the collagen in the eye. It can also help in cases of macular degeneration that affects the central area of the retina which might be due to the same property of there glucoside.

Moving away from the eyes and back to the vascular system, the collagen cross-linking properties of the flavonoids, which is what anthocyanosides basically are, can help to repair damaged vein tissue by strengthening the vein walls themselves, and also by providing support for the cell membranes, or outer layers of the cells.

This in turn builds up more strength in the vein tissue below the outside walls and contributes to an overall reduction in the weakness of the vein. This in turn enables it better to withstand the internal pressure put upon it by the failure of the valve that created the problem. In this way bilberries can be used to help repair the damage done by varicose veins and improve the function of the vein in returning blood to the heart from the extremities of the legs and also to help reduce the pain and swelling of varicose veins.

In addition to these beneficial effects on the vascular system and the eyes, bilberry can also help to decrease the permeability of the blood-brain barrier to pollutants, drugs and other undesirable chemicals by improving the resistance of the capillaries in the brain to the transfer of such substances through their walls. It does so by preventing the collagen of the capillaries in the brain being degraded either by enzymes or other agents, Also, by helping to strengthen that collagen structure so that it becomes more impermeable to the larger molecules that form the pollutants.

A lesser known constituent of bilberry is myrtillin, an anthocyanoside monoglucoside that is also available in all green plants, that possesses anti-glycemic properties. What this means is that it can reduce hyperglycemia and glycosurea, and so reduce blood sugar without reducing the blood sugar level to dangerously low levels. In other words it is an ideal insulin substitute.

Native Americans used green plants for teas for centuries and were free from diabetes until the came into contact with Europeans and adopted their dietary habits. Although the case has to be proved, it appears highly likely that it was the myrtillin that kept them free from a condition that affects so many other races.

Irrespective of that, however, it is for its powerful antioxidant effect that bilberry finds its best use, and also its effects on varicose veins. However, all of the above health benefits that bilberry provides, can likely be laid at the door of the combined antioxidant effect of its vitamin C content and the anthocyanosides – including the glucoside myrtillin.

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Date: April 02, 2008 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Osteoporosis With Minerals To Build Bones And Improve Quality Of Life

Bone consists predominantly of collagen and calcium phosphate. The collagen provides the connective framework for bone that is hardened by the calcium phosphate, and without healthy bones, your quality of life would be significantly reduced due to bone breakage. That is why it is essential to supplement this framework with the vitamins and minerals needed to maintain a good bone density at those periods in your life when bone density is liable to deteriorate.

This begins to happen between the ages of 30 and 35 and in women and accelerates during the menopause, when your ovaries stop producing the hormone estrogen that is necessary for the maintenance of healthy bones. Through time, your bone mass drops creating first a condition known as osteopenia, or reduced bone mass, and then osteoporosis, when your bones become brittle, porous and very prone to fractures.

Before we look at what can be done to reduce your chances of developing osteoporosis, lets have a close look at how bone develop so that it will be easier to understand the remedial action that can be taken.

Calcium is the most common mineral in the body, and the vast majority is in the bones and teeth. Phosphorus is also essential for healthy bones because as stated earlier, the bone consists of collagen that is hardened by calcium phosphate. The two main uses of phosphorus are in bone structure and animal metabolism, since phosphates are also essential for the vast majority of the energy-production chemical reactions within your body.

Calcium has other functions within the body other than bone, however, including exchange of fluids within and between cells, the maintenance of your heartbeat and in blood clotting. Vitamin D is necessary to help calcium be absorbed from your diet, through the membranes of the duodenum. More calcium is absorbed there than in the small intestine, and the calcium is also most available to the body when it is in a water-soluble form.

In fact, the reason that stones form in your kidney for example, is that the calcium is rendered insoluble through the formation of calcium oxalate from the oxalic acid in foods such as rhubarb and soy. High fat diets can also slow down the absorption of calcium.

Estrogen plays a significant part in bone physiology, and is an important factor in the maintenance of bone density in women. Bone is living tissue, and is constantly being absorbed and remodeled throughout life. The part played by estrogen is to maintain a proper balance between the osteoclasts, the cells that reabsorb bone tissue, and osteoblasts, the cells that form new bone tissue.

When estrogen is deficient, this balance is lost and rather than bone formation and resorption occurring constantly, they take place in spurts so that first an area of new bone will be formed, then resorption will occur some weeks later, resulting in a structure where there are cavities between areas of bone. With time, these cavities will increase and weaken the integrity of the bone structure.

However, that is not the whole story. The effect of estrogen is to limit the active period of osteoclasts so that the areas of bone resorbed into the body are relatively small so that the removed bone cavity can easily fill up with new bone by the osteoblasts, which are invigorated by estrogen. When estrogen is deficient, not only is the activity of the bone-forming osteoblasts reduced, but the bone-absorbing osteoclasts activity is not regulated, and they form deeper holes in the bone structure than the osteoblasts are able to fill.

The net result is bone loss, with more bone being reabsorbed than is being formed. The end result of all this is spongy bone tissue with many tiny hole and also with larger areas of missing bone. Eventually this passes a critical point and the bone fractures during normal use. A simple jump from one step to another can fracture a bone at its weakest point, such as at the hip joint where the neck of bone is thinner.

Not everybody is at the same risk, and there are certain risk factors that you should be aware of, each of which could increase the chances of you developing weak bones. The condition particular affects white or Asian women, and those who have a small frame. If you smoke and drink an excessive amount of alcohol, you will also be more prone to osteoporosis, although exercise can help you to avoid it. An inadequate intake of calcium and vitamin D will also contribute, and magnesium is an essential part of strong bone development.

The U.S. Department of Agriculture has carried out surveys that indicate American women to be taking only 50% of the calcium recommended to maintain a healthy bone density. However, it is not only dietary calcium that is needed for the formation of bone, but also magnesium and boron, and vitamin D also helps with the absorption of calcium in the gut.

If you are on steroids then they can render you more prone to brittle bone disease. Unfortunately the symptoms of osteoporosis do not become evident until there has been a significant amount of bone loss, which is why post menopausal women, and those over 65, should have a bone density scan (DXA test). It is important to understand that osteoporosis is not a disease as such: you cannot ‘catch’ it, but it develops as the result of a gradual reduction in the minerals that maintain the density of your bone structure.

Your diet is important in helping you prevent bone loss and osteoporosis later in life, and your lifestyle is also important. Reducing your daily alcohol intake will certainly help, and cigarette smoking further retards the activity of the bone-creating cells. Calcium and vitamin D supplements will help, but do not restrict yourself only to these.

If you want to maintain proper bone density through and beyond the menopause stage of life, you should take a balanced supplement that contains a combination of vitamins and minerals needed to maintain a healthy balance between natural bone loss and regeneration. There is more to it that only calcium and vitamin D, and a balanced supplement takes this out of your hands. You can rest in the knowledge that you are doing the best for your body and its bone density.

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Date: March 27, 2008 11:07 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Msm Is Good For More Thank Just Joint Health

When asked to think of essential minerals, sulfur is probably not the first item that comes to your mind. But organic forms of this element shine brightly within every cell. No type of sulfur shines more brightly than methylsulfonylmethane, which is commonly known as MSM. MSM helps to form a vital connective tissue component and is best known as a joint supplement. However, skin is made of the same basic stuff, a strong protein called collagen, so it isn’t surprising that MSM also provides cosmetic benefits.

Collagen, which is a mesh of protein fibers that supports all the other skin cells, is what actually holds the skin together. These fibers are extremely flexible, yet very tough, with collagen actually having a greater tensile strength than steel. There are different varieties of collagen: type I through type XII. One of the main reasons that a child’s skin is so soft and smooth is that it is filled with type III collagen, which is the kind found in fast-growing tissue. As the child ages, this type is replaced with the tougher type I collagen. However, as the skin continues to age, the amount of collagen in the body begins to decline, causing wrinkles, discoloration, and other signs of skin aging.

The protein that is found within collagen is actually loaded with sulfur, which explains why MSM has been shown to restore a softer look to those people who use it. Users of MSM report that hair grows faster and thicker with the use of MSM and nails are also stronger. Some practitioners even found that scleroderma, which is a condition marked by thick, hard skin, actually is improved by the use of MSM.

Joints also contain collagen and MSM delivers sulfur to these tissues, which is what made it a great supplement in the first place. Among people ages 40 to 76 with arthritic knees, MSM improved the symptoms of pain and physical function. MSM is even more effective when taken in conjunction with other joint aids including glucosamine and chondroitin. One study showed that glucosamine and MSM reduced pain and swelling more quickly when they were taken together than when taken separately.

MSM also seems to help ease pain by directly stopping pain signals as they travel along the nerves. This ability has led to its use in treating conditions like back pain, carpal tunnel syndrome, fibromyalgia, and tendonitis. Along with younger looking skin, MSM users have reported another use: reductions in allergy miseries. Scientists have discovered that MSM seems to block histamine, which is the chemical that is responsible for allergic reactions, from reaching tissues such as the mucous membranes lining the nose.

Results from studies have been promising, as seasonal allergy sufferers report significant symptom relief and increased energy levels. For pain relief, fewer allergy attacks, and softer smoother skin, MSM is the best choice to provide your body with a healthy boost of sulfur. More information about MSM and its abilities can be found at your local health food store.

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Date: February 09, 2008 10:43 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Benefits of Ascorbyl Palmitate A Fat-Soluble Form of Ascorbic Acid

The benefits of ascorbyl palmitate are due to the substance being a fat-soluble form of ascorbic acid which is otherwise known as vitamin C. Before discussing why being fat-soluble should be of benefit, let us first have a look at what vitamin C does for us and what its limitations are.

Most people know vitamin C as the vitamin that prevents us from getting scurvy, and that limes and other citrus fruits were given to sailors to prevent them from contracting this often fatal disease on long journeys. However, important though the protection it provides against scurvy is, there are many more important uses for this important vitamin. In fact some of them are closely connected to the symptoms of scurvy.

Among these are pains and swelling in the joints, and the loosening of teeth and hair loss. Scurvy is also associated with easy bruising and bleeding. All of these can be associated with loss of collagen, which is contained in connective tissues, bone and blood vessels. Collagen repairs and maintains cartilage, heals wounds and is essential for proper skin formation and the structure of ligaments, tendons, blood vessels, bones, hair and teeth. When we consider that one of the most important properties of vitamin C is the part it plays in the production of collagen in the body, then its effectiveness in alleviating the symptoms of scurvy is not difficult to understand.

Vitamin C is also a strong antioxidant that destroys free radicals that kill and severely damage body cells, and cause a large variety of undesirable conditions such as atherosclerosis and cancers, and also debilitating and painful inflammatory conditions such as arthritis. Many free radicals are formed in the body as by-products of our metabolism: the generation of energy from fats and blood glucose. Others are ingested in the form of cigarette smoke and other toxins, while yet other free radicals are caused by the effect of sunlight on our skins. Natural antioxidants such as vitamins A, C and E help to keep these free radicals under control and minimize their effect.

Another interesting property of vitamin C is in the synthesis of carnetine, a deficiency of which is also thought to contribute to scurvy. Carnetine is needed by the body to transport fat to the cellular mitochondria so that it can be converted to energy. Vitamin C is also believed to take part in the biochemistry that converts cholesterol to bile acids and so helps to maintain a healthy level of cholesterol in the blood.

The vitamin is therefore a very useful one for the body, but it has one fault. It is water soluble, and hence cannot be stored in the body but is expelled in the urine. Had it been fat soluble it could have been able to be stored in the body fats, in the same way that vitamins A and E are, and be available for use when required. Instead any excess that is not immediately used is lost, and a fresh intake of ascorbic acid necessary on a continuous basis.

Not only that, but it is only of use in areas of the body that the blood can reach. Fatty tissue is practically devoid of vitamin C, and many areas of the brain cannot be reached by substances that are insoluble in oils and fats. It also finds it difficult to penetrate the skin and the walls of body cells. This is where the benefits of ascorbyl palmitate are useful.

Ascorbyl palmitate is a fat-soluble form of vitamin C and possesses all of the attributes of ascorbic acid. It is more easily absorbed by the body and can be stored in the membranes of the cells until needed. It is also a powerful antioxidant, the same as vitamin C, and is frequently used to prevent the oxidation of vegetables oils, such as on potato chips and other oily snacks. It also takes part in the biochemistry of the production of collagen and connective tissues.

The usefulness of this substance comes from not only from its amphoteric nature, whereby it has one end that is water soluble and another that is fat soluble, but also by the fact that it is also amphipathic, meaning that it prefers neither one medium nor the other, and tends to collect at phase boundaries, between oil and water phases. It is particularly effective in topical uses on the skin, because it is easily absorbed into the skin tissue, and more stable than some of the other forms of vitamin C. It is also believed to protect other fat soluble antioxidants such as vitamin E from oxidation, and also to help to protect blood cell membranes from free radical attack.

Although vitamin C is a very powerful vitamin, carrying out a multitude of tasks, ascorbyl palmitate has some advantages over it apart from the solubility difference. Its antioxidant properties are stronger than those of regular ascorbic acid and in fact rival those even of vitamin E, which it also helps to regenerate after its reaction with free radicals, and help to maintain a continuous supply of this powerful antioxidant.

It is also a chemically neutral form of the vitamin, and unlike regular ascorbic acid, does not cause inflammation of the tissues it comes into contact with. It can also reduce sunburn due to excessive exposure to UVB when applied to the skin, and is a very stable form of the vitamin. Ascorbyl palmitate also acts as an anti-inflammatory with certain conditions, such as psoriasis where topical application helped to reduce the extent of the lesions. In fact it appears to do most of what vitamin C does, but faster and with smaller doses.

So why is ascorbyl palmitate not used as the main form of vitamin C in supplements? The answer is money. Ascorbyl palmitate is considerably more expensive than regular vitamin C, and also normal ascorbic acid has some properties that the fat-soluble form does not have, such as its ability to rapidly pass through the body in the bloodstream.

However, it would make sense to take a supplement consisting of both forms of vitamin C, and so combine the best properties of each. Any vitamin C supplement that is designed for maximum effect on the body should contain at least 25% of ascorbyl palmitate, the balance being ascorbic acid. That is what to look for if you are to receive the combined benefits of both water and fat soluble vitamin C.

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Date: January 19, 2008 10:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Skin And Joint Health With Natural Supplements

A lot of health conscious adults are now attempting to keep a youthful appearance for as long as possible by exercising, taking growth hormone enhances, and using expensive cosmetics. However, studies have proven that the major signs of aging in the skin, joints, and eyes occur due to a progressive collagen and hyaluronic acid degradation in our tissues. Researchers believe that supplementation of these key nutrients can actually reverse sings of aging.

Normal functioning of the skin requires that there be normal physiological substances in and around the skin cells. Of the many substances that are required for normal functioning, collagen is one of the most important. Collagen provides structural support to skin, which helps to maintain skin tone, subtleness and elasticity. All of these give the skin its amazing beauty. Without enough collagen, our body would actually lose any connective properties and its ability to hold together, causing the sagging and wrinkles that are associated with age.

Hyaluronic acid is also a vital component of the skin's structure. HA is a big part of the space between living cells and is also present in both the dermis and epidermis, where it allows skin to retain moisture and acts as a lubricant between the collagen matrix of the skin. Younger looking skin typically has higher levels of HA, but it has been observed that hyaluronic acid content declines as we age, most dramatically after the age of 50. Most people after the age of 40 have already lost a lot of HA and may require supplementation. High concentrations of hyaluronic acid and chondroitin sulfate are able to reach the corium layers of the epidermis and provide cellar level nourishment to the skin. This then reveals a more vibrant and younger looking complexion.

Doctors believe that osteoarthritis affects more than 20 million Americans, with that number reaching 40 million by the year 2020. Some doctors believe we're headed for an epidemic of degenerative joint disease. Osteoarthritis is a degenerative joint condition marked by the erosion of the cartilage at the ends of the bones. Cartilage is the shock absorber of the joint, with regular wear and tear on the joints eventually softening, fraying, and thinning the substance. Other things that can cause cartilage degradation and osteoarthritis have recently been identified by scientists, including: weak quadriceps muscles, eroding cartilage, and changes in bone structure. Certain genes also play a role in predetermining cartilage status, and left untreated and unchecked, this can become extremely debilitating.

Since normal joint function requires healthy cartilage and bones, one of the most important substances required for the normal functioning of joints is collagen. As we age, it has been observed that there is a decrease in the production and concentration of collagen in the joints. The lack of this vital structure leads to joint pain and inflammation. Common treatments today include the prolonged use of painkillers and anti-inflammatory drugs, steroids, NSAIDs and COX-2 inhibitors which temporarily relieve pain and cover up the symptoms while the disease moves further. More often, these treatments worsen the condition instead of helping it due to their harmful side effects. A natural supplement containing Collagen II can not only halt the progression of arthritis but can also improve the condition and provide relief to sufferers.

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Date: November 22, 2007 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Support Healthy Joint Function With Discount Vitamins

The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime.

Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones.

Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain.

Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue.

A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders.

A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints.

The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover.

Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids.

Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks.

Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage.

Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement.

It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that.

That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results.

Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density.

There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium.

You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.

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Date: November 10, 2007 02:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Maca a Magic Root?

Maca is packed with nutrients; loaded with vitamins and minerals to help fuel brain function and ease hormone irregularities as well as nourish the body.

Maca contains:
1. vitamins: B1, B2, and vitamin C
2. Alkaloids: contains 4 novel alkaloids: Macaina 1, 2, 3, 4.
3. Bismuth: Aids in combating bacteria that causes gastritis.
4. Calcium: supports strong bones and teeth.
5. Copper: supporting hemoglobin production
6. Fatty acids: contains 20 fatty acids 7. Silicon: helps hair, skin, nails, and connective tissue.
8. Iron: supports hemoglobin also.
9. Magnesium: essential for protein synthesis, and activities of muscles and nerves.
10. Manganese: essential mineral
11. Phosphorus: regulates the transmission of neuromuscular chemicals and electrical stimuli. Important for the hemostasis of calcium, and the reactions of lipids, carbohydrates, and proteins. The body’s chemical energy is stored in phosphate compounds.
12. Potassium: participates in the regulation of osmotic pressure; its activity is carried out inside the cells.
13. sodium: when working with potassium helps reduce arterial pressure and hypertension.
14. Tannins: useful in the treatment of diarrhea. Combined with other medicines, they have the utility of treating inflammatory processes like ulcers and sores.
15. Zinc: a cofactor of dehydrogenises and carbonic anhydrite; its lack can cause skin rashes, taste disturbances, and mental lethargy.
16. Carbohydrates: quality carbs.
17. Fructose: Natural fruit sweetener
18. Micronutrients: minerals which help with the production of antibodies.
19. Proteins: rich in bio-available maca protein average of 11% grams in dry root.
20. Starch: chemical compounds that influence the nutrition and health of consumers.
21. Fiber: loaded with cellulose and lignin which stimulates intestinal operations.
22. Macronutrients: essential vitamins and minerals, nutritive properties to help convalescent people who are diagnosed with anemia.

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Date: November 09, 2007 05:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Protein And Its Role In Bodily Functions

Protein is an essential organic compound composed of 20 or more amino acids which are joined by peptide bonds. Proteins serve as structural material such as connective tissue, and hair (i.e. collagen and keratin) can function as enzymes and hormones, as transporters of essential substances such as oxygen, antibodies, or regulators of gene expression. The importance of protein cannot be overstated in its effects on overall health regardless of age. Dieters using the low-protein diet can be seriously lacking in many essential nutrients including minerals such as zinc, iron, manganese, chromium, copper, etc. These deficiencies can lead to chronic illness, fatigue and make mental function more difficult.

In order to fight sickness and disease, our immune systems need to be in optimum performance. Something you may not have realized but our immune system are almost all protein based. Providing the body with the correct proteins is like providing the proper building blocks of the immune system and can help to fight the common cold and infections better. Proteins are also used to repair muscles during exercise.

There are eight essential amino acids which the body cannot manufacture and which we must derived from our diet each day. The essential amino acids are (i) isoleucine, (ii) leucine, (iii) lysine, (iv) methionine, (v) phenylalanine, (vi) theronine, (vii) tryptophan, and (viii) valine. With this list of proteins it is possible to determine where we can find these amino acids and incorporate them into our diet. We need protein in our diet on a daily basis, especially for muscle function which requires a particular mix of amino acids which are not found in many food sources. For example, to increase muscle mass, you need glutamine, carnitine, taurine, and arginine amino acids.

Now that we know we need protein daily in our diet and that protein is essential to life. So the next question you may have is what kind of proteins are the best? Quality proteins found in your local grocery store can be found in meat, nuts, eggs, and other foods. If you turn to your local health food store, look at soy, casein, whey and egg proteins. The type of protein you take will depend upon what you are capable of eating, i.e. taste. Some people have trouble eating whey protein, while others cannot pallet egg protein.

The best protein found in nature however is derived from egg whites. Egg proteins are not only complete in its supply of what the body needs, the egg is rich in chlorine, niacin, potassium, magnesium, riboflavin, selenium, vitamin K, sulphur, and omega-3. An added bonus to eating egg whites is the lack of cholesterol and sodium in the yoke. Eggs are also one of the most tolerable proteins in the human body where over 90 percent of the proteins derived from eggs is digested into the individual amino acids our bodies need. By eating egg derived protein you are essentially supplying the body with the raw materials it needs for proper function. So, if you have been troubled by fatigue, poor hair and nails the answer may be to increase your protein intake or try an all natural egg white protein for three to four weeks and see what a difference it will make in your health and appearance

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Date: October 18, 2007 03:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamin and Herbal Alternatives For Joint Health

Joint tissue breaks down and arthritis sets in for a number of reasons, and there are several natural alternatives for joint health that can be use to prevent this and to treat affected joints.

Thyroid problems can slow down the production of adrenal hormones that are responsible for the production of cortisone and cosrtisol. These are anti-inflammatories, that when unavailable or in low supply can result in joint inflammation. If you suffer joint pain in the mornings that tends to improve as the day goes on, then it is likely that is the cause since adrenal activity can improve as the day progresses.

One of the main reasons for joint tissue breakdown is osteoarthritis whereby the cartilage wears down until it fails to provide the necessary protection against impact between the bones in a joint, or against the friction generated when two bones rub together. Injuries to joints can have the same effect, whereby an injury to a hip or knee can appear to clear up and then later the cartilage wears out sooner than expected. This can take several months or many years, depending on the severity and nature of the injury concerned.

Continual wear and tear can also cause joint tissue to break down. Athletes and other sportspersons often suffer twenty years or more after retirement from their sport due to the gradual wearing down of cartilage while they were active. Once they stop, this continues to a lesser extent until the cartilage is eventually worn away sufficiently for it to stop protecting the joint.

Problems with the auto-immune system can lead to rheumatoid arthritis and inflammation of the joints. This weakens them and can eventually completely destroy the tissue. In such cases the tissues in the joint tend to swell and become extremely painful. Gout can also damage joints, especially in the big toe. This is caused through a built up of needle sharp uric acid crystals. Another cause is a deficiency in sodium and potassium in the diet that are needed to help maintain calcium in solution. When these metals are in deficiency due, for example, to an adrenal problem or some other reason, calcium can deposit right in the joints, causing undue pain.

Calcium and vitamin D deficiencies are commonly associated with arthritis sufferers, and protein deficiencies are also believed to be a contributing factor of rheumatoid arthritis, and it is also true that degenerative arthritis can accompany rheumatoid arthritis. This occurs in almost 40% of cases, and diet and nutrition are now being recognized as a major cause of both types. Deficiencies in folic acid or its natural form of folate, vitamin E, zinc and selenium have all been associated with degeneration of joint tissue, so it makes sense that a supplement of these substances can help to avoid these conditions.

Standard medical treatment, however, is for the relief of pain and reduction of inflammation through the prescribing of non-steroidal anti-inflammatory drugs (NSAIDs). Typical NSAIDs are aspirin, ibuprofen and naproxen. Although it relieves pain, paracetamol is not an anti-iflammatory. An alternative to blocking the inflammatory reponse is to help to regenerate the damaged joint tissue.

However, reducing the inflammatory response to tissue damage does not address the underlying problem, but masks it. Not only that, but there are side effects associated with the use of NSAIDs. Excessive doses can create serious gastrointestinal problems, such as bleeding, ulcer perforation and even death is possible in severe cases. Anti-inflammatories cause gastric problems in up to 20% of cases

The newer Cox-2 inhibitors act on the enzyme that causes the inflammation within the joint, and while these can be very effective, they are still masking the underlying problem. Incidentally, the Cox-2 inhibitors should not be used with NSAIDs, and both increase the possibility of a myocardial infarction or heart attack. Also, if you are taking aspirin to reduce the risk of heart problems, you should be careful not to use other NSAIDs since they can interfere with the effects of the aspirin.

More effective in the long run is to treat the conditions with substances that deal with the cause of the problem. Vitamin C, for example, improves the lubrication effect of the synovial fluid in the joints, and vitamin E is a strong antioxidant that can help to repair damaged tissue and improve the circulation within the joints. Joints have very low blood circulation levels, which is a problem when trying to direct drugs to the joint tissues. Vitamin C is also good for improving the integrity of connective tissue. Zinc, manganese and copper are also instrumental in developing strong connective tissue and helping to repair the damage done to the joints.

Horsetail is a commonly used herbal remedy that can be taken as a tea, tincture or in capsules. It is the richest natural herbal source of silicon, which is used by the body to form connective tissue and collagen. Damaged connective tissue is rapidly repaired by horsetail, and its strength and elasticity significantly improved. It is commonly used in the treatment of arthritis and osteoporosis.

Cat’s Claw is used for its beneficial effect on the immune system, and frequently used successfully to treat osteoarthritis and rheumatoid arthritis. However, this treatment is used more to help reduce the inflammatory effects of the condition than to effect a long lasting cure. Gotu Kola, also called Indian pennywort, is traditionally used for treating arthritis. The fresh leaves are effective in reducing the inflammation and pain, and help to improve the quality of life of arthritis sufferers. In Australia, it is referred to as ‘the arthritis herb’ and two leaves a day are said to be effective.

Another popular remedy is MSM (methylsulfonylmethane), although it is claimed to provide pain relief rather than a cure. Amino acids also seem to help, and L-cysteine helps promote collagen and connective tissue. It appears to work best when taken in combination with vitamin E and selenium that are powerful antioxidants. L-arginine has a similar effect in the reconstruction of joint tissue, again helping to repair damaged connective tissues.

There are therefore two approaches to treating both rheumatoid and osteoarthritis, one providing pain relief and reducing inflammation, and the other repairing the damage done to the joint tissues. Vitamins, minerals, trace minerals and herbal remedies are used in both, though it is better to use a combination that provides pain relief and also helps to regenerate strong connective tissues in the joints.

When using combinations of remedies it is important that possible interactions are understood, and you should always seek the advice of your physician when using non-prescription remedies of any kind.

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Date: June 26, 2007 02:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: OptiMSM

Eighty percent of Americans over 50 years old suffer from some form of degenerative joint disease, and many others suffer from sports injuries, tennis elbow and tendonitis, which can result in symptoms not unlike arthritis—soreness, stiffness, and general pain in the region. An ever widening number of people are newly discovering a well-established natural remedy for these symptoms—and numerous others—with MSM.

Methylsulfonylmethane (meth-l-sul-fonil-meth-ane), or MSM, is a natural nutrient found in many foods and is a vital building block of joints, cartilage, skin, hair and nails. It also supports a wide number of biochemical processes in the body, including energy production.

Due to the demineralization of the earth over time, many naturally occurring elements—including MSM- are not available in foods in high enough quantities to deliver therapeutic value. As a dietary supplement, MSM must be synthesized. When made correctly, it is identical to what is found in nature, and can be taken alone or in combination with other health supplements.

According to Stanley W Jacob, MD, Ronald M Lawrence, MD, PhD, and Martin Zucker, authors of The Miracle of MSM, MSM is rapidly establishing a reputation as a safe, natural and effective solution for many types of pain and inflammatory conditions, including degenerative wear-and-tear arthritis, rheumatoid arthritis, chronic back pain, chronic headaches, muscle pain, Fibromyalgia, tendonitis, and bursitis, carpal tunnel syndrome, TMJ, post-traumatic pain and inflammation, and heartburn. MSM also has benefits for allergy sufferers. According to Jacob, Lawrence and Zucker, “After many years of treating pain patients with MSM, it has become clear that perhaps a single most powerful benefit it offers is quick relief of the symptoms of common allergies. In hundreds of cases, this nutritional supplement has proved highly effective.”

The primary reason for MSM’s value is its high sulfur content. MSM contains 34 percent sulfur—the fourth most abundant mineral in the human body and one critical to making collagen, the primary constituent of cartilage and connective tissue. MSM is thought to deliver sulfur to the body in a usable way so it can be incorporated into these tissues. Many people using MSM as a dietary supplement have attested to its effectiveness.

“I was acquainted with an elderly woman who had been on Prednisone for severe arthritis for a number of years,” says Rob Benjamin, director of quality control for Bergstrom Nutrition in Vancouver, Washington. “Her doctor had to take her off of it because of what it was doing to her kidneys. Her knuckle joints were about an inch and a half thick. I gave her a sample of MSM, then ran into her about six days later. She came up, threw her arms around my neck and took her gloves off, and the thickness of her knuckles had reduced to almost normal. All the swelling was gone.”

The leading MSM product, manufactured to the most stringent product specifications available, is OptiMSM®, made by Bergstrom Nutrition. The crucial step that makes OptiMSM of such a high quality is its distillation process, in which heat is used to separate pure MSM from impurities and the by-products of manufacturing. The company has evolved the exact boiling points that allow MSM to be isolated, consistently producing the purest MSM available.

“Our methods are more expensive and more energy intensive,” Says Benjamin. “But our prime concern is delivering the purest product available.”

Peter Gilliham’s Natural Vitality is proud to include OptiMSM in its daily multi nutrient Organic Life Vitamins (OLV).

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Date: April 25, 2007 03:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Do you experience muscle pain and inflammation?

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Improve Flexability with Vitamins at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1529)

Date: April 20, 2007 12:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Learn about Bone Health!

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Build Strong Bones with Vitamins from Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1523)

Date: April 04, 2007 09:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hyaluronic Acid Double Strength 100mg – w/ Proline, Alpha Lipoic Acid & GrapeSeed extract.

Hyaluronic Acid has emerged as one of the most significant anti-aging supplements in the natural products industry. As a mucopolysaccharide that occurs naturally within the human body, the highest concentrations of Hyaluronic Acid are found in the skin, eyes, and articular cartilage. Hyaluronic acid works by absorbing water within the body, which in turn supports the formation of effectiveness of the gel-like matrix that protects healthy cell structures from dehydration and free radical damage. Ongoing studies continue to suggest that it may help support some of the body’s most vital functions.*

Strong, Healthy Joints

At birth and well into our youth, the human body produces ample amounts of Hyaluronic acid. These levels decline, however, based on our physical activity levels, dietary habits, and other hereditary and environmental factors. Hyaluronic acid is a key component of synovial fluid and cartilage, and serves as one of the body’s most vital natural lubricants. Joint structures lack blood vessels, and there for relay on Hyaluronic acid to transport fluids and nutrients. Many structural and articular challenges have been traced back to insufficient Hyaluronic levels.

Wrinkles and Fine Lines

Healthy, wrinkle-free skin requires a constant supply of water. Without enough, dermal cells located deep below the skin’s surface can becomes deprived of the compounds they need, thus leaving the skin dry and dehydrated. Hyaluronic acid attracts and binds large amounts of water at the cellular level to ensure that the skin has everything it needs to remain smooth, elastic, and youthful-looking.

Wound Healing

Some published reports suggest that a child’s ability to produce abundant amounts of Hyaluronic acid may explain why they heal so quickly, often without permanent scarring. Because of the many roles it plays within the body’s connective and epidermal tissues, Hyaluronic acid is becoming more and more accepted as a way to help encourage the body’s natural wound-healing processes.

Vision and Eye Health

In addition to cartilage and synovial fluid, the eyes contain some of the body’s highest concentrations of Hyaluronic acid. In fact, the vitreous humor (the Eye’s Core) is made up almost entirely of Hyaluronic acid. This gel-like structure absorbs shock, supports vision, and protects the retina from being damaged. It is believed that many common vision and ocular problems may be a result of poor Hyaluronic acid production during adulthood.*

Each Vcap contains 100mg of Hyaluronic acid, along with Alpha Lipoic Acid, standardized Grape Seed Extract, and pharmaceutical grade L-Proline for support. Compare Now’s 100mg formula to some 50mg formulas that do not include supporting antioxidants for the same price, and the choice is clear!

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Let Vitanet Help you Look, Feel and Live Healthier with Hyaluronic Acid

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1504)

Date: March 26, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supplements good for reducing stress and boosting energy!

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Buy Energy and Stress Formulas at Vitanet Health Food Store ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1496)

Date: March 08, 2007 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Revita

Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.

Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.

To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.

Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.

Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.

Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.

In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."

In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:

• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.

• 78.9% of subjects showed an increased mean value of hair diameter.

• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."

Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.

Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:

• Total Number of Hairs: Significantly Increased

• Total Number of Terminal Hairs: Significantly Greater

• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher

• Hair Follicle Activation: Intensive

In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.

Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.

Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.

The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.

Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.

Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.

Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.

Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.

Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.

If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.

Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.

The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.

Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.

After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.

Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.

MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.

The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.

MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.

Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.

The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.

According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.

The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.

Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.

Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.

The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.

Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.

Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.

Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.

L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.

The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.

Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.

In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.

Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.

Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.

Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.

Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.

After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.

This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.

Q. Is Revita safe ?

A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.

Q: Can I use hair sprays, mousses, gels, etc.?

A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.

Q: Can I have my hair colored or permed while using Revita ?

A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.

Q: What is SLS/SLES free ?

A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.

Q: Can I blow dry my hair after using Revita ?

A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.

Q: Who is a candidate for Revita ?

A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.

Q: What type of results should I expect with Revita ?

A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.

Q. Does Revita have any systemic side effects ?

A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.

Q. Does Revita work for women?

A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.

Q. I am using other topical treatments. Can I use Revita at the same time ?

A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.

Q. Do I need to use Revita for a long time ?

A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.

Q: Is stress a factor in hair loss?

A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1480)

Date: February 06, 2007 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fruit and Vegetable Lightning drink mixes from Natures Plus

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Buy fruit and Vegetable Power drink mixes at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1451)

Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.

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for Great Joint Health buy Best Joint Support at Vitanet

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Date: September 07, 2006 12:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are Amino Acids?

Amino acids are the smallest molecules that comprise protein, commonly referred to as the “building blocks of life” – they build all body and tissue protein. Seventy-five percent of the body’s solid weight is made up of proteins and their constituent amino acids. Unable to be efficiently stored in the body, amino acid reserves must be re-supplied continuously.

Twenty three amino acids support the growth, repair and maintenance of about 1600 different types of proteins in the human body, including muscles, connective tissues, hormones, enzymes, antibodies, hair, skin, nails and blood.

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Buy Amino Acids and Free-Form Amino Acids at Vitanet

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Date: August 29, 2006 09:18 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Camu Camu Powder Extract

Benefits

100% Natural Wild-Crafted Vitamin C*

Camu camu is one of the richest natural sources of this potent antioxidant vitamin in the world. Every gram of Best Camu Camu 4:1 extract contains at least 200 mg of natural, wild-crafted vitamin C. This is in addition to a synergistic host of additional nutrients that potentially enhance the uptake of the antioxidants in the extract.

Vitamin C is critical to numerous organs and systems throughout the body. It serves as an important cofactor in a number of physiological processes that occur on a daily basis. Vitamin C protects molecules including lipids, proteins and DNA from free radical damage and serves to regenerate other potent antioxidants, including vitamin E. Vitamin C is also a required factor for the synthesis of collagen and connective tissue, plays a prominent role in energy production, helps in the formation of the neurotransmitter norepinephrine, and supports immune health.1 An adequate daily supply of vitamin C is necessary for the maintenance of these and other critical physiological processes.

Strengthens Antioxidant Defenses*

Anthocyanin compounds, such as cyanidin-3-glucoside found prominently in camu camu fruit, are natural pigments responsible for the brilliant colors seen in fruits.2 They also possess significant antioxidant activities as well as other potential health benefits. Furthermore, studies show that anthocyanin compounds are rapidly absorbed in humans and other mammals. Recent studies have shown that the stomach and small intestines are the predominant sites of absorption into the bloodstream.3

Research conducted on cyanidin-3-glucoside confirms its potent antioxidant activity. In vitro assays have been performed evaluating markers of free radical damage including DNA cleavage, free radical scavenging capacity and xanthine oxidase activity. In this study, cyanidin-3-glucoside showed protective effects on DNA cleavage, inhibition of xanthine oxidase and dose-dependent free radical scavenging abilities.4 Studies in rats also confirm the beneficial effects of this anthocyanin. In one such study, feeding this compound to rats was shown to increase the resistance of rat serum to oxidative changes, suggesting a potent antioxidant effect of this compound.5

Camu camu is a potent source of cyanidin-3-glucoside and has a high content of the ubiquitous, water-soluble antioxidant, vitamin C. Together, these nutrients serve to strengthen antioxidant defenses against free radical damage*. Best Camu Camu 4:1 Extract provides a natural, wholesome way to infuse the body with its daily requirement for vitamin C and additional free radical-fighting anthocyanin compounds.

Safety

Suggested Adult Use: Take 1 more capsules daily, with or without food

Scientific References

1. Linus Pauling Institute. Micrnutrient Information Center. Monograph on “Vitamin C”. //lpi.oregonstate.edu/infocenter/vitamins/vitaminC/

2. Zanatta CF, et al. Determination of Anthocyanins from Camu-camu (Myrciaria dubia) by HPLC-PDA, HPLC-MS, and NMR. J Agric Food Chem 2005. 53: 9531-9535.

3. Talavera S, et al. Anthocyanins are efficiently absorbed from the small intestine in rats. J Nutr 2004. 134: 2275-2279.

4. Acquaviva R, et al. Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage protectors and antioxidants. Cell Biol Toxicol. 2003 Aug;19(4):243-52.

5. Tsuda T, et al. Dietary cyanidin 3-O-beta-D-glucoside increases ex vivo oxidation resistance of serum in rats. Lipids. 1998 Jun;33(6):583-8. Buy Camu Camu at Vitanet

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Date: August 24, 2006 03:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Degenerative joint disease (osteoarthritis)

Degenerative joint disease (osteoarthritis) damages or destroys cartilage and its supportive collagen structure. As many as 40 million Americans, including the majority of people over age fifty, are thought to suffer from some form of this disease. Primary osteoarthritis, the “wear and tear” form, is due to normal use and age-related causes. Secondary osteoarthritis results from repeated joint trauma, inherited predisposition, or previous inflammatory conditions. While non-steroidal anti-inflammatory drugs (NSAIDs) treat symptoms only, a natural, holistic approach strives to improve the environment of the cartilage and joint as a whole by providing protective and restorative nourishment, increased circulation, decreased inflammation and reduced free radical damage.

High levels of Glucosamine and Chondroitin Sulfate

Widely regarded as the first defense in protecting joints, glucosamine and Chondroitin sulfate have been shown to effectively control joint pain and slow down or reverse the progression of cartilage deterioration. The integrity of joint gliding surfaces as well as the health of tendons, ligaments, joint fluids, skin, bones, heart valves and virtually all structural elements in the body is dependent upon the proper synthesis and availability of proteoglycans, integral components of joint cartilage.

Glucosamine provides two components critical to the synthesis of proteoglycans: hyaluronic acid and glycosaminoglycans (GAGs).

Chondroitin sulfate represents an important group of GAGs. It is not a single compound, but rather a class of compounds with different molecular weights that each have specialized functions within the body.

Numerous studies have shown that long-term safety, reduction in pain and protection of cartilage with body chondroitin and glucosamine are comparable or superior to results obtained with NSAIDs.

MSM. (Methylsulfonylmethane) MSM is a rich source of sulfur, a mineral required for GAG synthesis. A preliminary study suggests that MSM may help reduce pain in persons with degenerative arthritis.

Gota Kola. (Centella asiatica) known to support collagen synthesis and stimulate GAG’s, Gota Kola has been used for many years in Europe to promote wound healing and blood vessel integrity. It also has been shown to improve circulation in small vessels.

Turmeric. (Curcuma longa) this saffron-colored root offers a wide range of benefits. It naturally inhibits the inflammatory COX-2 enzyme, reduces pain and is a potent antioxidant that protects the liver and other cells. High antioxidant diets may inhibit joint deterioration.

Bromelain. Derived from pineapple cores, Bromelain is most commonly used for healing soft tissue injuries and inflammation. It contains potent selective proteases (protein-digesting enzymes) and other substances which serve to block destruction of GAGs.

Trace Minerals. Micronutrients play many distinct roles in support of healthy joint connective tissue and joint cartilage matrix.

Black Pepper Extract. Bioperine is a highly concentrated extract (95% - 98% piperine) of black pepper. Used as a bioavailability enhancer, it has been shown to increase the absorption of vitamins, minerals and herbs.

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Solaray Vitamins

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Date: July 26, 2006 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of taking Vitamin C Daily

Vitamin C benefits

1. maintain normal connective tissue and wound healing.

2. help strengthen bones.

3. Vitamin C is a Cofactor in the production of epinephrine (adrenalin).

4. Vitamin C helps in the production of Bile acids for digestion.

5. Vitamin C helps in the production of Thyroxin (Thyroid hormone).

6. helps in the absorption of Iron.

7. aids in amino acid metabolism.

8. helps strengthens the body during infection.

9. helps counter oxidative stress.

10. may help strengthen veins and aid in diabetic retinopathy.

11. Vitamin c may help reduce the binding of glucose to proteins in diabetics.

12. in large doses Vitamin C has shown to have an antihistamine effect and may be helpful with asthma and allergies.

13. Vitamin C is needed for the synthesis of L-Carnitine, L-Carnitine helps transport fat into cells to burn as energy.

1000mgs of vitamin C each day helps keep the doctor away ;)

for proper vitamin C intake try Alacer Emergen C drinks...

Also try: Now Vitamins for great Vitamin C!

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Date: June 22, 2006 09:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cell Rejuvenator by Peter Gillham formulation

Cell Rejuvenator is Peter Gillham’s formulation that creates good health on a cellular level.

It’s in the formulation

Cell rejuvenator is a precisely engineered formula designed to give cells the exact nutrients they need to rejuvenate quickly and in the best condition possible. The formulation contains MSM (methylsulfonyl methane—a source of organic sulfur derived from nature), vitamin C, bioflavanoids and zinc. While primarily used for its anti-aging benefits, Cell Rejuvenator has a great many applications.

What’s in Cell Rejuvenator?

Peter Gillham’s Cell Rejuvenator is a complete formulation, not just another MSM product. Cell Rejuvenator starts with Lignisul MSM, which guaranteed 99.9 precent pure and is an assurance of a high standard of quality necessary for optimal health benefits. Lignisul MSM is extremely safe, non-toxic and non-allergenic.

Then we’ve added vitamin C the perfect companion to MSM. MSM helps to speed new cell formation and vitamin C is one of the primary nutrients the body looks for in making new cells. While MSM helps release toxins, vitamin C neutralizes them.

Bioflavonoids are another part of the Cell Rejuvenator formula. They greatly enhance the absorption of vitamin C. along with this, bioflavonoids help promote a strong immune system, improve circulation, and help maintain healthy cholesterol levels.

Cell Rejuvenator also includes zinc one of nature’s “super minerals.” Zinc is responsible for accelerating healing and for the formation of DNA in our tissues. DNA is essentially the blue print the body follows when forming and renewing itself, piece by piece, starting with each new cell.

How you benefit

Cell Rejuvenator releases toxins with MSM, neutralizes them with vitamin C, promotes a stronger immune system, improved circulation and healthy cholesterol levels with bioflavonoids, and accelerates healing and cellular DNA formation with zinc.

MSM is an important nutrient and a key ingredient in Cell Rejuvenator. It is needed by the body for healthy connective tissue and joint function, proper enzyme activity and hormone balance, along with correct functioning of the immune system.

Just how important is it? Approximately half of the body’s total sulfur is concentrated in the muscles, skin and bones. It is also present in keratin, the tough substance in the skin, nails and hair. Sulfur is necessary for making collagen, the primary constituent of cartilage and connective tissue.

Supplementation with MSM has been found to improve many health situations, such as allergies, asthma, emphysema, lung dysfunction, arthritis, headaches, skin difficulties, stomach and digestive tract problems, circulation and cell absorption.

MSM is non-allergenic and has no undesired pharmacological effects. One cannot overdose with MSM the body will use what is needed and flush out the rest without harm. Because it is also a free radical and foreign-protein scavenger, MSM cleans the bloodstream, so allergies to foods or pollens can be eliminated sometimes in just a few days.

Beauty Secret

We have all heard that with age the skin loses its elasticity, but do you know why? When the body replaces old skin cells, if there is a deficiency of MSM, the new cells are stiff and contribute to wrinkling. Taking Cell Rejuvenator helps the body replace bad cells with good, healthy elastic cells.

Easy to use

The ingredients in Cell Rejuvenator are mixed in exact amounts to achieve what we feel is the best recipe for cell rejuvenation. Cell Rejuvenator is available in convenient capsules and in powdered form. If you prefer capsules we recommend four capsules a day (2400mg). if they want to take a higher therapeutic does, they may prefer the powdered form, which easily mixes with your favorite juice. Some people see results within days, while it can take weeks for others. The key to success is to be consistent in taking Cell Rejuvenator.

A constant supply of the ingredients in Cell Rejuvenator is required to build the healthy cells needed for proper organ functioning and for maintaining healthy skin, hair and nails. When you stop to think about the fact that our bodies produce cells 24 hours a day, you get some idea of how vital Cell Rejuvenator is!

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Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

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Date: February 22, 2006 05:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Rutozym - Systemic Enzyme Supplement with Nattokinase

Wobenzyme / Naturally Vitamins Choose all-vegetarian Rutozym for smoother blood flow, stronger blood vessel walls, and a pacified inflammatory response. Take Control of Your Heart Health Heart disease claims an American life every 34 seconds, making heart disease the leading cause of death in the United States. Not only men, but also one out of every two women are affected by heart disease and stroke. According to the American Heart Association, misperceptions about the risks of cardiovascular disease for women still exist, even though 50 percent of people with heart disease today are women, and more women than men die of stroke. After menopause, women are even more likely to have heart attacks than men. Because of today’s standard of American fast-food diets and poor lifestyle habits, many people have high cholesterol and hypertension and suffer from circulatory disorders. People with excessive body fat are more likely to develop heart disease and stroke, even if they have no other risk factors. Obesity increases the strain on the heart, which contributes to coronary heart disease and can also make diabetes more likely to develop. People in many other countries have somehow managed to maintain healthier hearts naturally. One reason may be the enzymes in their diet. Nattokinase and Cardiovascular Health Experts credit much of Japan’s reputation for the lowest heart disease rate to nattokinase, an enzyme in the fermented soy-based cheese called natto. Although a Japanese staple for over 2000 years, the sticky, odorous cheese is, needless to say, an acquired taste. Fortunately the advantage is in the enzyme, now available in Rutozym. Hiroyuki Sumi, MD, a researcher of the Japan Ministry of Education, discovered the enzyme and its remarkable benefits while searching for a natural way to break down excess fibrin in the blood, a major cause of heart disease, stroke, senility and even sudden death. Pleased with how successfully it dissolved fibrin and improved blood flow, Sumi (affectionately known as “Dr. Natto”) gave nattokinase its name. Rutozym In the 1980s when the story of systemic enzyme therapy was well underway, scientists invited Dr. Karl Ransberger, founder of the enzyme formula Wobenzym, to Japan to present his discoveries in enzyme research. The country’s low rate of heart attacks and its dietary link to natto intrigued Dr. Ransberger. Eager to investigate its potential use in alternative healthcare, he carried several pounds of natto home to Europe. After years of testing, his research confirmed that nattokinase did, in fact, improve blood flow by removing cross-linked fibrin from the blood stream. Based on his nearly five decades of experience with the proteolytic Natural Support for Cardiovascular Health (protein-splitting) enzymes in Wobenzym, Dr. Ransberger knew that an enzyme mixture would prove even more effective than a single enzyme formula. So, to the nattokinase he added two of the enzymes in Wobenzym known to normalize inflammation. Then he increased its total effect with a proprietary flavonoid complex. As a result, the formula not only improved blood flow, it strengthened the integrity of blood vessels and helped manage the body’s systemic inflammatory response, promoting better overall health. Dr. Ransberger teamed up with Naturally Vitamins to further develop, test and perfect the Rutozym formula. Today, Dr. Ransberger’s legacy lives on through Naturally Vitamins’ continuing research on systemic enzyme therapies. Most recently, Naturally began a 2003 clinical trial in Chicago to evaluate the benefits of Rutozym in heart patients. In cooperation with the leading manufacturer of Nattokinase in Japan, the trial will examine the effects of Rutozym on blood viscosity (thickness) and blood pressure. On completion, the results will be published in a peer-reviewed journal. How Rutozym Works Rutozym works by reinforcing your body’s own enzymes. As the building blocks of life, enzymes make every chemical action in the body possible. Though you are born with thousands of enzymes, as time goes by your supply diminishes. Scientific research shows that replenishing your natural supply with systemic enzymes can support your body’s immune functions and healing processes. Rutozym is a plant-based systemic enzyme formula containing nattokinase. But it also contains other proteolytic enzymes and ingredients carefully blended to improve heart health and enhance your body’s innate ability to heal. Rutozym contains the proteolytic enzymes bromelain (from pineapple) and papain (from papaya) known to effectively rebalance the body’s inflammatory response. Rutozym also contains rutin to strengthen capillaries and other connective tissue, and white willow bark, which is often called “nature's aspirin.” While doctors often recommend an aspirin a day to help prevent heart disease and stroke, the daily use of Rutozym has no gastrointestinal side effects. With new research, the scope of Rutozym’s benefits continues to increase. Supplement Facts Serving Size: 2 Tablets Servings Per Container: 60 amnt/serving %daily Nattokinase (20,000 FU/gm) 25mg * Bromelain (2,450 GDU/gm) 90mg * Papain N.F. (2,400 USP Units/mgl) 100mg * Rutin bioflavonoid Complex (rutosides & rutinosides) 120mg * White willow bark extract (15% solicin/7% plyphenols) 100mg * * Daily value not established. Other Ingredients: Plant Fiber, Povidone, Modified Cellulose Gum, Colloidal Silica, Titanium Dioxide Mineral, Vegetable Stearic Acid and pH-Resistant Enteric Coat. -- Buy Wobenzyme at Vitanet

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Date: December 27, 2005 05:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C FAQ's

Vitamin C FAQ's

What is Calcium Ascorbate?

Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.

What does Calcium Ascorbate do?

Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.

Is this a necessary vitamin or can our bodies make enough to satisfy our needs?

Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.

What is the function of the Citrus Bioflavonoids?

Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.

Why are there color variations in your different Vitamin C products, and are they safe to take?

Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.

Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.

Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.

NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.

Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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Date: December 22, 2005 09:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: JOINT HEALTH

Glucosamine & Chondroitin - JOINT HEALTH

Everyone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints.

Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of mobility. These nutrients are referred to as “chondroprotective agents,” and include glucosamine and chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with glucosamine and chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function.

Glucosamine and chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.

GLUCOSAMINE

Glucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on glucosamine sulfate and glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion.

The 106 patients on placebo had a progressive jointspace narrowing, while participants taking glucosamine experienced no significant joint-space loss, indicating glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of glucosamine sulfate or placebo daily for 30 days. The patients treated with glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5

CHONDROITIN

Chondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While glucosamine helps manufacture and maintain cartilage, chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6

NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both glucosamine and chondroitin as separate products, as well as in powder and lotion forms.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1064)

Date: October 26, 2005 12:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Research on SAMe....

Two groups of researchers have conducted analyses of trials that utilized SAM-e for mood enhancement. One meta-analysis was published in 1994. The researchers analyzed the efficacy of SAM-e in oral or injection forms based on published trials dated between 1973 and 1992. The authors concluded that there was a significant improvement of 17 to 38% seen in trials of SAM-e compared to placebo response. They state that the efficacy of SAM-e was superior to placebo and its administration caused few side effects.5 A second review was published in 2002. The authors analyzed studies in which SAM-e doses ranged from 200 to 1600 mg daily. They also found a significant effect of SAM-e in comparison to placebo, with an evident rapid onset of effect at enhancing mood.6

Promotes Joint Comfort and Mobility*

As a sulfur donor to connective tissue, SAM-e plays a major role in protecting the integrity of cartilage tissue. An in vitro trial assessed the actions of SAM-e in cultured human articular chondrocytes. At a concentration of 10 micrograms/ml, proteoglycan synthesis and sulfate residue incorporation in chondrocytes was shown to be 60% higher than control levels. Based on these results, it was shown that SAM-e has a positive influence on the growth and health of cartilaginous connective tissue.7

In a double-blind trial with 734 individuals with compromised joint health. SAM-e given orally at a dose of 1200 mg daily for 30 days was shown to significantly promote joint comfort compared to placebo, with a high level of tolerability and low incidence of side effects. The researchers concluded that SAM-e is a highly effective supplement for enhancing joint comfort.8

Another trial evaluated the response of individuals experiencing discomfort in the joints to a regimen of 1200 mg SAM-e for 1 week followed by 800 mg for the second week, and then 400 mg for weeks 3 through 8. This open trial of 20, 641 people showed a strong ability of SAM-e to enhance feelings of comfort within the joints. The treatment was rated as “very good” or “good” in 71% of the participants, with an additional 21% rating the treatment effect as “moderate”.9

In a long-term trial lasting 24 months, SAM-e was given to 108 participants with compromised joint function. Individuals were given 600 mg orally per day for the first two weeks followed by 400 mg daily for the remainder of the trial. Individuals experienced significant enhancements in joint comfort, with dramatic improvements noted after 2-4 weeks of treatment. Improvements continued to 6 months and beyond.10

In addition to the above studies, a review was conducted in 1987 to assess the results of SAM-e supplementation in clinical trials for enhancing joint mobility and function. Over 22,000 individuals had participated in the clinical trials that were the subject of this review. The author concluded from his analysis that SAM-e was shown to be highly efficacious, rivaling or surpassing the effectiveness of other treatments, and also possessing a high level of safety.11 Because of this, SAM-e may be the treatment of choice for enhancing joint function.

Supports Liver Health and Detoxification*

SAM-e supplementation can have profound benefits on liver function. These benefits center around its function as the major methyl donor in the liver, as well as its lipotropic activity. SAM-e also enhances the production of the antioxidant glutathione.

A number of trials have been conducted showing the ability of SAM-e to support liver detoxification functions and enhance liver health in individuals susceptible to toxin-induced liver compromise. SAM-e has the ability to normalize liver function by increasing the activity of enzymes needed to upregulate liver detoxification. These effects are comprehensive and rapid. Dosages used in these studies range from 600 mg to 1600 mg daily for 2 months to two years.12,13,14 In these trials, significant benefits of SAM-e supplementation were seen over placebo.

Safety

SAM-e has an excellent safety profile and is considered well-suited for long term use based on multiple clinical trials. Individuals diagnosed with manic depression should avoid SAM-e supplementation, as it may aggravate the manic phase *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1. Agnoli A, Andreoli V, Casacchia M, Cerbo R. Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms. J Psychiatr Res. 1976;13(1):43-54.

2. De Leo D. S-adenosylmethionine as an antidepressant. Curr Ther Research. 1987;41(6):865-70.

3. Kagan BL, Sultzer DL, Rosenlicht N,Gerner RH. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990 May;147(5):591-5.

4.Salmaggi P,Bressa GM,Nicchia G,Coniglio M,La Greca P,Le Grazie C.Doubleblind, placebo-controlled study of S-adenosyl-L-methionine in depressed postmenopausal women. Psychother Psychosom. 1993;59(1):34-40.

5. Bressa GM. S-adenosyl-l-methionine (SAMe) as antidepressant: metaanalysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. 6.Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr. 2002 Nov;76(5):1158S-61S.

7. Harmand MF, Vilamitjana J,Maloche E, Duphil R, Ducassou D. Effects of Sadenosylmethionine on human articular chondrocyte differentiation. An in vitro study. Am J Med. 1987 Nov 20;83(5A):48-54.

8. Caruso I, . Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease. Am J Med. 1987 Nov 20;83(5A):66-71.

9. Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. Report of an open phase IV study with ademetionine (Gumbaral). Am J Med. 1987 Nov 20;83(5A):84-8.

10. Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med. 1987 Nov 20;83(5A):89-94.

11. di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med. 1987 Nov 20;83(5A):60-5.

12. Frezza M, et al. S-adenosylmethionine counteracts oral contraceptive hepatotoxicity in women. Am J Med Sci. 1987; 293(4):234-238.

13. Frezza M, Surrenti C, Manzillo G, Fiaccadori F, Bortolini M, Di Padova C. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology. 1990 Jul;99(1):211-5.

14. Mato JM, et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol. 1999 Jun;30(6):1081-9.

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Research on SAMe - Vitanet ®

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Date: September 30, 2005 10:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vegetarian Glucosamine - Promotes Healthy Joints

New Product Announcement

Vegetarian Glucosamine - Promotes Healthy Joints