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CuraMed Acute Pain Relief: New Clinically Proven Technology to Ease Your Pain ![]() ![]() ![]()
Date:
July 26, 2022 02:05 PM
Containing a blend of BCM-95® Curcumin, BOS-10® Boswellia, Black Sesame Seed Oil, to ease pain and inflammation. How can CuraMed Acute Pain Relief help ease the pain you're experiencing? CuraMed Acute Pain Relief is a non-addictive, safe, and natural formula that can help ease the pain you're experiencing. The ingredients in CuraMed have been shown to be effective in reducing inflammation and pain. Curcumin, the active ingredient in CuraMed, has been shown to be as effective as ibuprofen in reducing inflammation. Boswellia and ginger are also included in the formula, and both of these ingredients have been shown to be effective in reducing pain. CuraMed is easy to take and can be taken up to four times daily. The recommended dosage is two Softgels per day. What are the ingredients in this product, and how do they work together to provide relief from pain and inflammation? BCM-95® Curcumin is a natural compound that has been shown to be effective in reducing inflammation and pain. Boswellia, also known as Indian Frankincense, has been used for centuries to treat a variety of ailments, including arthritis and joint pain. Black sesame seed oil is a triglyceride that is rich in omega-3 fatty acids, which are known to have anti-inflammatory properties. These three ingredients work together to provide relief from pain and inflammation. Curcumin inhibits the production of cytokines, which are inflammatory compounds that can damage cells and tissues. Boswellia prevents the breakdown of cartilage, and black sesame seed oil inhibits the activity of the COX-2 enzyme that contribute to inflammation. Together, these ingredients provide natural relief from pain and inflammation. How should you take CuraMed Acute Pain Relief for best results? For best results, CuraMed Acute Pain Relief should be taken 2 softgels daily. In severe cases, the recommended dosage is 4 to 6 softgels throughout the day. If you're looking for a safe, non-addictive way to ease your acute pain, CuraMed Acute Pain Relief may be the solution you're looking for. The product contains clinically studied ingredients that have been shown to be effective in reducing inflammation and pain. Curcumin, boswellia, and black sesame seed oil are the key ingredients in this formula, and they work together to provide relief from pain and inflammation. CuraMed is easy to take and can be taken up to four times daily. The recommended dosage is two Softgels per day. What's stopping you from living pain free?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6420) 8 essential oils which may help in rheumatoid arthritis ![]() ![]() ![]()
Date:
February 09, 2019 10:05 AM
If you suffer from rheumatoid arthritis, there are some essential oils that may help relieve the discomfort. This autoimmune disease causes inflammation and joint pain. It can cause swelling, joint stiffness, or loss of joint function completely. Since there is no cure, some natural oils may help with symptoms. Eucalyptus and Frankincense oil help reduce inflammation, swelling and pain. When inhaled, lavender oil can help with pain, anxiety, and depression. Evening primrose oil is also an anti-inflammatory and can reduce the stiffness in the joints. Key Takeaways:
"No cure is available to give relief from this problem, but a proper treatment can help in managing the pain and control the inflammatory response." Read more: https://timesofindia.indiatimes.com/life-style/health-fitness/photo-stories/8-essential-oils-which-may-help-in-rheumatoid-arthritis/photostory/67093015.cms
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6013) Powerful organic compounds in cannabis can slash some cancers by 50%, researchers say! ![]() ![]() ![]()
Date:
January 19, 2019 10:52 AM
Terpenes is a compound found in citrus fruits, rosemary, frankincense, and cannabis. Because it includes many compounds including THC, ketones, esters, lactones, and THC not found together in the same rate in other plants, it is a better health treatment than anything created by the pharmacy companies. Terpenes also has limonene and pinene, which help with anti-inflammation in healing cancers, and reducing stress. Joy Smith shares a story of having cancer, trying chemotherapy and being given just weeks to live, but attributes cannabis oil to saving her. Key Takeaways:
"Medical marijuana is a booming industry, and the use value of cannabis just continues to expand as we learn more about this heavily prohibited, but clearly medicinal, plant." Read more: https://www.naturalnews.com/2018-11-23-organic-compounds-in-medical-cannabis-slash-some-cancers.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5978) 6 Reasons why boswellia is one of the most powerful herbal extracts available today ![]() ![]() ![]()
Date:
January 19, 2019 10:09 AM
The more common name for boswellia is frankincense, and it is known for having a plethora of health benefits. Frankincense is made from the gum resin that originates from the boswellia tree. This boswellia resin has the ability to promote several incredible health benefits such as helping fight against various cancers, as well as preventing them in the first place. This is due to the anti-inflammatory aspects of frankincense, and an acid called Acetyl-11-keto-?-boswellic acid that naturally has the ability to fight cancer. Key Takeaways:
"This herbal extract has a long history of being used as perfume, incense, and medicine due to is therapeutic and anti-inflammatory properties." Read more: https://www.naturalnews.com/2019-01-15-6-reasons-why-boswellia-is-one-of-the-most-powerful-herbal-extracts-out-there.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5976) Hematuria: What Causes Blood in Urine? ![]() ![]() ![]()
Date:
July 02, 2017 09:14 AM
Hematuria is the term for having blood present in your urine. it can be caused by urinary tract infections, kidney stones, and more. Often, it is not serious, but it can be a sign of a serious problem. You should see a doctor but there are things you can do to treat the root problem. It can also be caused by a variety of things. Any person can have to deal with this issue in their lifetime regardless of age or gender. Key Takeaways:
"Blood in the urine can originate at any point along the urinary tract from the kidneys to the urethra" Read more: https://draxe.com/hematuria/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4914) Can CBD Help you Lose Weight? ![]() ![]() ![]()
Date:
February 25, 2017 10:59 AM
CBD has been in the headlines and in the spotlight for those battling many different health ailments. Many supporters say that it works better at treating common and uncommon health problems that might affect you. Now, new research is available, suggesting that weight loss is another problem that CBD can help. Learn the facts here. Key Takeaways:
"Most of the four million medical marijuana patients in the U.S. get their license recommendations from a doctor they never see again." Reference: //www.huffingtonpost.com/entry/can-cbd-help-you-lose-weight_us_58ae853ce4b0ea6ee3d035e6&ct=ga&cd=CAIyGmM2M2RhZjlmZTVmZDZjMmU6Y29tOmVuOlVT&usg=AFQjCNEpFcRtWM-vTQ4RaSCl6tkqKeCS9Q
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4020) Boswellia Reduces 5-LOX Activity ![]() ![]() ![]()
Date:
December 09, 2016 01:35 AM
Do you tend to suffer from allergic reactions and inflammatory diseases which come as a result of chemicals which are naturally secreted inside the nucleus of the body cells? Well, certain chemicals, such as 5-lipoxygenase is such a reagent inside the blood and it can lead to things such as inflammation in the leukotrienes and other cancer-promoting conditions of the human body. This can even lead to other kinds of discomforts such as joint pains and aches, lung infections and infections of the intestinal tract. As such, it is very important that its activity as well as the impact on the person is reduced. Luckily, there is a solution for that and this comes in the form of Boswellia. Acting to counteract the effects of 5-LOX, Boswellia otherwise known as Indian Frankincense has got a powerful impact on the said chemical which is responsible for the allergic reactions and inflammation of the body cells in the first place. As a result, these reactions are reduced thus promoting a healthy state of being. It is said to be the best natural fighter against the killer cancer and since it comes in an easy to assimilate form, it can get into the body system quickly thus acting to fight reactions just in the nick of time. It is truly important to live a healthy life which is free from all kinds of infections and allergies which can develop into further complications for the person. When you have a powerful drug to help with fighting such reactions within your body, you will notice that your body becomes progressively powerful and thus makes you able to withstand certain elements whose imbalances in the body might lead to inflammation. With Boswellia, you are able to become stronger against diseases naturally and you will also observe a gradual progression to a healthier, happier, more wholesome individual.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3601) Are your storable foods mostly just reprocessed GMO corn? ![]() ![]() ![]()
Date:
December 08, 2016 08:59 AM
Stocking up on non-perishable foods seems like an intelligent concept on the surface. But upon closer examination, it may prove that they stored food you buy contains genetically-modified organisms and additives that are toxic to your system. Transgenic corn, corn startch and high-fructose corn syrup are widely used in storable foods, but are nto organic products and are derivatives of "Frankencrops." Many popular brands that sell packaged food use these subtances to increae the shelf life of the food, but the presence of these chemicals in concerning. Key Takeaways:
"not all storable food is the same, and that much of it is actually loaded with things you probably wouldn't want to feed your families" Reference: //www.naturalnews.com/056114_emergency_food_preppers_GMO_corn.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3596) Powerful natural ways to relieve stress, anxiety ![]() ![]() ![]()
Date:
November 13, 2016 03:04 PM
Need a few new ways to calm anxiety and stress naturally, without prescription drugs? Here are 10 unique ideas for calming your nerves by activating your senses in new ways. From breathing exercises to keeping a journal and trying some new herbal teas there is sure to be one or two options here that are worth a try for those looking for alternative ways to relax. Key Takeaways:
"When emergency strikes and you feel a panic attack coming, simple breathing exercises can reverse the situation" Reference: //www.naturalnews.com/055926_stress_relief_anxiety_natural_remedies.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3438) The Health Benefits of Boswellia ![]() ![]() ![]()
Date:
September 09, 2016 10:17 AM
Boswellia, also known as the Indian Frankincense, is a popular native tree in traditional medicine. The tree has numerous health benefits due to its anti-inflammatory properties. The following are some of them:
Chronic inflammation is at an epic high in America, largely due to poor diets. Taking boswellia daily can help reduce inflammation helping the body fight off diseases that may arise.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3276) Boswellia - The Anti-Inflammatory Herb ![]() ![]() ![]()
Date:
July 23, 2015 03:07 AM
Boswellia is some times referred to as Indian Frankincense or boswellin. It comes from a tree known as boswellia serrata that is found to grow in the dry areas of India. Boswellia is said to have 55% of Boswellic acid. For centuries, many Indian healers have always taken the advantage of the anti-inflammation property of this tree. The bark's gummy resin contains anti-inflammation content in higher percentages - its known as salai guggal. In the modern world, preparations are done from a purified extract of the resin and normally packed in cream or pills which are then used mainly to reduce inflammation; rheumatoid or osteoarthritis arthritis. Unlike nonsteroidal anti-inflammatory drugs, like ibuprofen, which is one of the accepted treatments for joint inflammation, - boswellia according to research does not show signs of stomach irritation. It's also sometimes effective when it comes to back pains and other chronic related intestinal disorders. Its health benefits, according to research by scientists, has been outlined that this herb has specific and very active anti-inflammation ingredients. These ingredients are commonly known as boswellic acids. In the field of animal studies, boswellic acids have been proven to reduce inflammation. They improve rapidly the blood flow to the joints. They also do block those chemical reactions that always sets the stage for inflammation that cause chronic intestinal disorders. Boswellia maybe taken internally or even applied topically to the affected joints to help relieve inflammation that is associated with joint disorders. These always increase joint mobility and lessen the morning stiffness. In a study that was conducted involving 175 patients suffering rheumatic disorders such as rheumatoid arthritis, exactly 122 participants were found to experience reduced inflammation and stiffness after using boswellia for two to four weeks. Boswellia's inflammatory component helps reduce stiffness and aching, especially when associated with the low back pains. Though a lot of researches done shows that boswellia is effective when taken orally, creams also appear to be soothing all together. Boswellia also seems to reduce the inflammation related with Crohn's and ulcerative colitis disease, of which both are painful intestinal disorders. It's said to be able to accomplish this without actually the risk of gut irritation which is mainly associated with lots of convectional pain relievers. In the ?year 1997, a study was conducted involving ulcerative colitis victims, 82% those who took this boswellia extract like 3 times in a day, they experienced total and complete remission of this disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3180) The Health Benefits Of Frankincense Oil ![]() ![]() ![]()
Date:
February 17, 2014 06:39 AM
What is Frankincense
Uses of Frankincense Frankincense oil is used in the treatment of many medical conditions, diseases, and infection. Some of the diseases include wounds, wrinkles, dry skin, sore muscles scars, and other skin problems. Other than treating these infections, research has also revealed that it is able to treat cancer, arthritis, and anxiety. A study conducted by scholars from the University of Oklahoma revealed that Frankincense oil has the ability to differentiate between cancer cells and normal bladder cells. This study also revealed that this product could help in inhibiting growth and development of cancer cells in an individual. Due to this fact, it can be used to instigate the death of cancer cells on the bladder. Another separate research conducted by scholars from Virgina-Maryland school of Veterinary Medicine in 2006 found that Frankincense oil could be used in relieving horses from skin cancer lesions. Another important benefit of Frankincense oil is that it causes relaxation and general mood control in individuals. For this reason, it is used as an incense in many cultures around the world. It does this by targeting specific parts of the brain and the nervous system. Frankincense oil can also be used in the treatment of osteoarthritis. Source
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3022) Boswellia, How It Works And Its Health Benefits ![]() ![]() ![]()
Date:
December 02, 2013 07:30 AM
What is Boswellia? ![]() Also known as Indian Frankincense, boswellia is actually a natural herb that is commonly used in Ayurveda( a traditional medicine of India).The herb comes from the resin of boswellia tree which is actually rich in boswellic acid ( a substance that has anti-inflammatory effects)The herb is used to treat chronic inflammatory illnesses as well as other health conditions.
How it works.
Various studies indicate the boswellic acid can actually prevent the formation of leukotrienes in the human body. Studies also show that leukotrienes are the main cause of inflammation and can also triggers asthma symptoms. The four acids in boswellia resin are the major contributor to the herbs anti-inflammatory properties.
Health Benefits of Boswellia
1. Asthma
A study that was conducted in 1998 showed that boswellia may help to relieve asthma. The result of the study indicated that 70% of the patient who took 300mg of boswellia 3 times daily for 6 weeks showed a great improvement in their symptoms as compared to 27% who did not took it. This is because the herb actually helps in reducing leukotrienes which causes the bronchial muscles to contract.
2. Cancer
Studies shows that boswellic acid has the ability to prevent certain enzymes from affecting the DNA negatively thus helping to prevent cancer growth.
3. Arthritis
A study that was published in 2008 suggested that boswellia can help boost physical functioning and reduce pain to patient suffering from osteoarthritis (OA) of the knee. The study that was done using 30 patients who suffered from OA found out that those patients who used boswellia reported to have a decrease in knee pain .They also show some improvement on how far that could walk and flex their knee.
4. Colitis
Colitis is an inflammatory bowel disease that actually result in chronic inflammation of the digestive tract. A study that was conducted in 2007 on 31 people suffering from colitis indicated that those patients who took 400mg of boswellia 3 times daily for 6 weeks were actually more likely to go into remission as compared to those who took placebo.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2912) Boswellia Can Help you to Reduce all type of Inflammation Pain ![]() ![]() ![]()
Date:
November 06, 2013 09:15 PM
What is Boswellia ![]() There are so many natural medicines that can help you to fight against pain and boswellia is one of them. This is one of those herbs that are being used by various cultures as an effective pain killer since a long time. Other than this, this herb is also known to the world as Indian Frankincense and it can help you in inflammation as well as circulation of joints and stiffness of muscles.
Benefits of Boswellia Talking about the effect of boswellia on pain, many modern researches also proved that it works great as an anti inflammatory medicine. These researches proved that boswellia contain a triterpenoids that is commonly known as boswellic acids and this is responsible for relief in pain. These researches also proved that t boswellic acids are highly beneficial in pain and it has very few toxic or harmful content compared to any other popular anti inflammatory product.
Effect of Boswellia Other than this, researchers did some blind study in which they included 30 people that had problem of osteoarthritis of knee and researched compared the effect of boswellia against placebo that is another good anti inflammatory product. In this study participants either received boswellia as an anti inflammatory product or they got placebo for initial 8 weeks. After that researchers switched the medicines for next 8 weeks and patients found that they received much better result in pain with boswellia compared placebo. Additionally they also found great improvement in knee mobility, walking and reduction of knee pain while consuming boswellia.
On the basis of these researches and its history we can easily say that boswellia can easily help you to fight against any kind of pain it gives great result in case of muscles stiffness or joint pain. Other than this, its anti inflammatory property can help you in variety of other pain including sprain, fatigue or hurting.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2881) How Curamin Combats Inflammation Pain ![]() ![]() ![]()
Date:
December 19, 2012 12:08 PM
Fact: You can manage pain with natural remedies! Study has revealed the sad fact that four out of every five Americans perceive that pain is a natural inevitable part associated with old age. Athletes on the other hand believe that severe pain is essential for physical fitness. Many people again, think that there are certain disorders that ignite pain and you can do less or nothing to relieve the ache. In fact, 28% of America's population believes that there is no solution that can eliminate their personal pain concerns. In the contrary, Curamin by EuroPharma is a highly effective herbal remedy that combines four powerful and clinically proven ingredients, into a single award-winning product that offers an ultimate level of pain relief. Here is a look into how Curamin relieves inflammation pain. #Curamin's Ingredients The secret behind Curamin's power is blending the best of the best. These ingredients are well known for their fast action in relieving pain associated with inflammation especially in the bones and joints. Here are the four main ingredients used in the formulation of this unprecedented pain reliever. *DLPA (DL-phenylalanine) This is a double part amino acid (D phenylalanine & L phenylalanine) that impedes the breakdown of the enkephalin compound, also known as the positive mood enhancer. In addition to that, DLPA converts the L phenylalanine into tyrosine so as to enhance the secretion of two brain chemicals; norepinephrine and dopamine, which ease pain and dissolve inflammation. *Boswellia Boswellia serrata, also known as Indian Frankincense is an anti-inflammatory herb used in the Curamin formula. The boswellic acids prevent the hyperactivity of an enzyme called lipoxygenase, which is often associated with inflammation. This way, it effectively combats inflammation pain. *Nattokinase This natural ingredient is extracted for a Japanese fermented cheese known as natto, hence its name. The production of this beneficial enzyme can be attributed to a certain bacterium called Bacillus natto. Its benefits in relieving pain come through its action of breaking down clots, promoting the circulation of blood. Thickened blood can intensify pain, and by promoting blood circulation, all other Curamin ingredients are well distributed to every single part of the body. *Curcumin This powerful, natural compound derived from turmeric requires no detailed introduction. It promotes the body's natural ability to combat inflammation and also contains anti-oxidant properties that are very useful in preventing tissue damage. Its functionality in pain relieving is behind its effectiveness in cutting off pathways that lead to inflammation. Numerous studies have also depicted its ability to promote cognitive-enhancing as well as anti-depressant benefits by igniting neuro-protective brain functions and moderating pain neuro-transmitters. #How Curamin Relieves Pain This proprietary formula combats inflammation pain by promoting the body's defense mechanism. In addition to that, it features curcumin BCM-95 which has an enhanced oral bioavailability and is highly soluble, thus availing a full spectrum or curcuminoids that fight pain in a flash. Additionally, the amino acids and Boswellia used in the formulation of Curamin helps the body to absorb the pain alienating ingredients quickly, which earns Curamin its well deserved fast-acting characteristic. Curcumin BCM-95 has extended blood retention; one among the many attributes that makes Curamin stronger than other plain curcumin products. We cannot forget to mention the fact that Curamin is associated to no known side effects. It combats all types of pain ranging from occasional back pain to chronic pain caused by arthritis. So, next time pain becomes a problem, grab a bottle of Curamin and make your life a whole lot easier.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2752) How Does Boswellia Fight Inflammation? ![]() ![]() ![]()
Date:
April 13, 2011 03:57 PM
Boswellia refers to the species of trees where the aromatic gum resin Frankincense is obtained from. In herbal medicine, the term Boswellia often means Indian Frankincense, which is noted for its potent anti-inflammatory properties. It has a centuries-old association with Ayurvedic medicine, and herbal preparations containing its extracts are formulated for arthritis. It now comes in supplements marketed as a viable treatment for inflammation-induced illnesses, such as arthritis, colitis, and asthma. Asthma Indian Frankincense, also known as dhoop in India, is entirely derived from Boswellia serrata, and the common Frankincense from a completely different species. The earliest known study looking into its purported benefit as an anti-inflammatory medication was in 1998, and it investigated its effects on asthma. In a span of 6 weeks, the boswellia group took 300 mg of the preparation three times a day and 70 percent experienced a significant improvement in symptoms and a noticeable decrease in incidence of asthma attacks in comparison with the control group. Arthritis In Ayurvedic medicine, boswellia has been utilized for hundreds of years with an emphasis on its use in the amelioration of joint pains. It is generally considered safe, explaining its prevalence in the treatment of arthritis and related disorders. Boswellia was the subject of several studies devoted to better management of osteoarthritis, and these studies published results that attracted more research. Today it is also touted to be useful for rheumatoid arthritis, which is inflammatory in nature. Colitis Recent studies yielded outcomes in favor of its anti-inflammatory claims. In 2007 one study pointed to its medicinal potential in the treatment of colitis, concluding that patients with chronic inflammation of the colon went into remission after regular intake of boswellia. In a similar study, individuals diagnosed with inflammatory bowel disease reported to have benefited from 6 weeks of supplementation while those who sought conventional treatments responded to their medications in a much longer time. 5-lipoxygenase Boswellia remains under scrutiny. Anecdotal evidence has been very positive largely owing to the fact that it hasn’t been linked to any adverse effect at all. But how does it work? There are many chemical reactions which boswellia may be directly involved in. It has been observed that it reduces the synthesis of pro-inflammatory leukotrienes. These mediators of inflammation are produced in the presence of an enzyme called 5-lipoxygenase, which is thought to be counteracted by the high terpene content of boswellia. Leukocytes Triterpenes in boswellic acid, the active ingredient unique to boswellia, are also believed to interfere with the adhesive interactions between leukocytes and endothelial cells present in the gastrointestinal tract. Leukocyte elastase is a serine protease, a special kind of enzyme, released by leukocytes or neutrophils during inflammation. It is postulated that boswellia down-regulates leukocytes and leukocyte elastase in addition to inhibiting the expression of endothelial cells adhesion molecules. Down-regulation of leukocytes will help reduce inflammation and improve health. If you are fighting systemic or joint inflammation, give boswellia a try and feel the difference!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2272) Boswellia Extract ![]() ![]() ![]()
Date:
June 11, 2009 06:16 PM
The boswellia family of trees are specifically known for their fragrant, gummy sap, which possesses many medicinal uses. Among these, especially, if the use as an anti-inflammatory. It is believed that the Frankincense of the bible was actually an extract from the resin of the Boswellia tree. Boswellia, which is also known as boswellin, has a long history of use in Ayurvedic healing. The resin is called salai guggal and has been used to treat asthma, arthritis, various inflammatory conditions, and to relieve joint pain and pain that results from sports injuries. The resin of the boswellia tree is also though to be helpful for treating back pain as well as some other chronic intestinal disorders. The boswellia plant is a genus of trees that are known mainly for their fragrant resin. This resin has many pharmacological uses, particularly as anti-inflammatories. There are four main species of boswellia, producing true Frankincense. Each type of resin is available in various grades. These grades depend upon the time of harvesting. The resin of the boswellia plant is hand sorted for quality. Anyone who is interested in Frankincense is advised to obtain a small sample from each reputable dealer to determine the difference between each resin. Boswellic acids are the main compounds that are believed to be at the source of boswellia’s anti-inflammatory properties. These acids have the ability to inhibit the enzymes that induce pain and inflammation in the body. A few studies have been conducted on boswellia’s effect on sports injuries and arthritis. Among these, some have shown that boswellic acids may contain anti-inflammatory benefits that are extremely powerful. These benefits are similar to those found in ibuprofen and aspirin. One study done on rheumatoid arthritis patients found that pain and swelling were reduced after three months of treatment with boswellia. Those who used boswellia occasionally reported mild gastrointestinal distress, like heartburn and nausea, but there were no other reports of serious side-effects. Boswellia has a long tradition of safe and effective use as a mild anti-inflammatory to alleviate pain and stiffness. It is also used to enhance mobility without serious side effects. However, further research is needed to confirm the long-term safety and effectiveness of this extract. Boswellia seems to be best taken as needed in order to reduce pain and stiffness, as opposed to being taken regularly as a maintenance herb. The resin of boswellia is used in many herbal formulas because of its analgesic and anti-inflammatory properties. Primarily, this extract is most useful in dealing with arthritis, asthma, inflammatory conditions, joint pain, and sports injuries. A boswellia standardized extract is recommended by many doctors. When dealing with rheumatoid arthritis or osteoarthritis, 150 mg of boswellic acids are taken three times per day. For example, if an extract contains 37.5% boswellic acids, 400 mg of the extract would be taken three times daily. Treatment with boswellia should generally last between eight and twelve weeks. Generally, boswellia is safe when used as directed. Rare side effects include diarrhea, skin rash, and nausea. Any inflammatory joint condition should be closely monitored by a health care professional. To date, there are no well-known drug interactions with boswellia. Boswellia comes in capsule form at your local or internet health food store. When making a purchase always read the label to ensure that the product is standardized to its active acids to ensure quality and purity and to ensure that the herb when taken regularly will function as intended. *Statements contained herein have not been evaluated by the Food and Drug Administration. Boswellia is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2017) The pediatrics academy has raised its earlier recommendation to 400 IU per day. ![]() ![]() ![]()
Date:
October 14, 2008 10:03 PM
The American Academy of Pediatrics (AAP) today announced that it has doubled the amount of vitamin D recommended for infants, children and adolescents. The increase, from 200 international units (IU) to 400 IU per day, starting in the first few days of life, was detailed at the group’s annual meeting in Boston. The new advice replaces an academy recommendation issued in 2003. "We are doubling the recommended amount of vitamin D children need each day because evidence has shown this could have life-long health benefits," said Frank Greer, M.D., FAAP, chair of the AAP Committee on Nutrition and co-author of the report. “Supplementation is important because most children will not get enough vitamin D through diet alone.” "Breastfeeding is the best source of nutrition for infants. However, because of vitamin D deficiencies in the maternal diet, which affect the vitamin D in a mother’s milk, it is important that breastfed infants receive supplements of vitamin D,” said Carol Wagner, M.D., FAAP, member of the AAP Section on Breastfeeding Executive Committee and co-author of the report. The new advice is based on mounting research about potential benefits from vitamin D besides keeping bones strong, including suggestions that it might reduce risks for cancer, diabetes and heart disease. But the evidence isn't conclusive and there is no consensus on how much of the vitamin would be needed for disease prevention. "We know 400 IU a day is safe and prevents rickets," Greer said. "We don't have any idea if that amount of vitamin D is enough for other diseases. We also don't know if anything over 400 is safe." The AAP also made these recommendations: Infants who are breast-fed or partially breast-fed receive 400 IU a day of vitamin D in supplements, beginning in the first few days of life, continuing unless the infant starts taking at least one quart a day of vitamin D-fortified formula or whole milk, although whole milk should not be introduced until the child has turned 1. Non-breast-fed children and older children should also receive a vitamin D supplement of 400 IU per day. Adolescents who do not obtain 400 IU of vitamin D per day through foods should receive a supplement containing that amount. Children at increased risk of vitamin D deficiency (for example, those taking anti-seizure medications) may need higher doses, but this should only be done in consultation with a health-care professional. The new recommendations were expected to be published in the November issue of the journal Pediatrics.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1915) Third- The Science (Putting It All Together) Boswellia & Inflammation ![]() ![]() ![]()
Date:
April 03, 2008 12:44 PM
Frankincense has traditionally been used in Ayurvedic medicine for centuries, and is even mentioned in the Bible. The trunk exudes a resin containing mono- and sesquiterpenes that possess powerful anti-inflammatory properties. They are also well known antiseptics and astringents, and support the immune and respiratory systems. These terpenes are commonly referred to as boswellian acids, and consist of a carboxylated pentacyclic triterpene with at least one more functional group. Both the alpha and beta acid have a hydroxyl (-OH) grouping, and there are also the acetyl (CH3CO-) equivalents with an acetyl group replacing the OH. There are other so-called-boswellian acids, and it is believed that they all play a part in the anti-inflammatory properties of the resin. The acetyl derivatives are thought to be involved in the death of some cancer cells, particularly those involve in brain and colon tumors, and also leukemia. The way in which they achieve this appears to be a programmed progression that ends with the dying out of the cells rather than a violently destructive mechanism, which lends credence to the Ayurvedic belief that the treatment is a natural one designed by nature. The anti-inflammatory properties of the acetyl triterpenes are due to their effect on leukotrienes that sustain the inflammatory reactions of many allergic reactions and also of asthma. They appear to inhibit the enzyme elastase in leukocytes; this is a crucial enzyme in the production of the chemicals that promote inflammation. It has been established that the inflammatory response of the immune system is due to the action of specific enzymes, so it stands to reason that if you can inhibit these enzymes, then you will also inhibit the immune response to specific initiators and so reduce the pain involved. Bosellian acid in the form of triterpenes appears to contain these inhibitors, and this would appear to explain its effectiveness. Pinene and phellandrene are among the terpenes isolated from Boswellia. A standardised dose of 60% - 65% of Bosellian acids is generally used, so if you are purchasing Boswellia this is what you should be looking for. Keep in mind that it is intended to treat inflammation, ands that inflammation is an indicator that something with your body is not quite right. Therefore, while inflammation is painful, and Boswellia may help, you should also treat the cause of the inflammation by treating the immune system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1741) Secondly, the Herb Boswellia ![]() ![]() ![]()
Date:
April 03, 2008 12:43 PM
Boswellia is a tree that has a number of different species that have been used in Ayurvedic medicine. This is a form of Indian medicine that is used today by millions in India, and also in the neighboring Nepal and Sri Lanka. Its approximate translation is ‘Meaning of Life’, or could even be subtended to ‘Science of Life’, and is more a system of health care than the treatment of specific conditions. There are four species of Boswellia: Boswellia carteri, Boswellia frereana, Boswellia sacra and Boswellia serrata, and it is B.serrata that is predominantly used in Ayurvedic medicine to treat a number of conditions, including ulcers, rheumatoid arthritis, dysentery and asthma. It is not coincidence that most of these are inflammatory conditions, and even dysentery is a form of inflammatory colitis. You might be more familiar with Boswellia by the fragrant resin that it produces: Frankincense. There are different grades of Frankincense according to the species and grade of Boswellia, and if you are using the resin for its aroma then that could be an important consideration. However, the active ingredient of Boswellia are the so called boswellic acids that are contained within the resin. It has been used in the treatment of a number of inflammatory conditions including asthma. Many do not realize that asthma is an inflammatory response of the immune system to particulate irritants in the airway such as cigarette smoke and other small particles. In this case the inflammation is caused by the histamine that is released by mast cells sent to the area of irritation by the immune system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1740) Loose Weight By Cutting Dietary Fat Absorption ![]() ![]() ![]()
Date:
December 08, 2007 06:24 PM
You can lose weight by cutting dietary fat absorption, although in order to understand the need for this you have to appreciate the effect that fat has on your weight. Not only fat, but any form of calories. The word ‘calorie’ appears to have a bad press, and there have been a lot of ill informed comments made about calories and whether calorie controlled diets are effective or not. Quite Frankly, it is all said in ignorance. Whether you agree or not, the calorie is a measurement of energy and the calorie content of foods is what is calculated to be the energy value of these foods. Once inside your body, that energy is either used up or converted to body mass. It is not necessarily converted to fat, since that extra weight could be in the form of muscle tissue. However, it is converted to body mass and so you can put on weight. The basic equation is that if you take in more energy than you use, then you add weight, and if you use more energy than you take in, then you lose weight. It is slightly more complex than that, but it is basically true. That does not mean that if you eat a pound of dripping (the fat that drips off cooking meat) you will add a pound of weight. It is the calorific value of the dripping in terms of energy, whether measured in calories or in joules, that is the relevant factor, and if that is 4000 calories, which is about average for various types of dripping, then if you use up 4001 calories in exercise, you can safely spread your pound of lard on toast and eat it without putting on weight (you will have also to use up the calories in the toast). It is the calorie equation that is important, and if this is negative then you will lose weight. You have to: it is a law of science! Whether your calories are in the form of cookies, candies, avocados (loads of them) or dripping, it is all the same. A meat calorie is the same as a vegetarian or vegan calorie. If you eat more than you use you put on weight. Different foods contain different quantities of energy, or calories. If you buy a Big Mac you eat 570 calories, and 5 from your Super Pepsi. If the guy next to you has an English Muffin, he will have 140 calories. However, if he then goes home and slouches on the sofa watching TV and you go to the gym for a serious workout, he is liable to put on weight and you lose it. It’s all in the equation! However, you don’t just use calories in exercise. Your metabolism is also important. In fact 65% - 75% of the calories you use in a day are used up by the body at rest: the metabolism that takes place 24/7 to keep you alive. The heartbeat, breathing and brain activity for example, all use up energy. So not all is doom and gloom, and you can burn up these calories even while you are sleeping. However, there is another way to prevent the fat you eat from turning into weight. (Incidentally, if you exercise a lot, that weight will likely be in muscle mass, but if not then it will certainly be fat). You have a clue to the way that can be done in the first sentence of this article: ‘dietary fat absorption’. If the fat is not absorbed into the body, then it is not available to be metabolized into body fat. It will pass through the body unchanged. It is not the fat you consume that makes you gain weight, but the amount of that fat absorbed through your intestines. But how is it possible to selectively prevent the fat in your diet from being emulsified by the bile and absorbed through the intestinal wall? By means of chitosan. This is a fiber that absorbs part of the fat from the food you have eaten and hides it away from your digestive system. It cannot be broken down into sugars and then into fat to add to your unwanted weight. However, because it works after your meal, you get to eat what you want – that ‘finger lickin’ good’ stuff you love, but don’t suffer the consequences of failing to exercise to work it off. It’s like you just ate lettuce without the fried chicken with the crispy fatty skin. So what is this miracle substance, chitosan? Biologists would recognize the name as being associated with chitin, the acetyl-glucosamine polymer that forms the carapaces, or shells, of crabs, lobsters and other marine shellfish. Chitosan is formed by deacetylating the chitin and is mainly used to enhance the growth of plants, and also as a filtration aid. So what does it do to help to remove some of the fat from your diet after you have eaten it? The mechanism by which it does this is not fully understood, and in fact is still disputed in some quarters. However, the proof of the pudding is in the eating and it appears to act according to the claims. There are two possible mechanisms, one of which is connected with the deacetylation of the chitin molecule. Because of this, the resultant chitosan molecule has cationic groups on the polymer chain. Cations are positively charged, and can react with acids, not the least of which are the bile acids that break down lipids (fats) to render them into a form suitable for absorption. It is possible for the chitosan to react with the bile acids and prevent them from breaking down the fats into a condition that enables them to be passed through the intestinal wall. However, it has also been proposed that dietary fibers work by increasing the thickness of the boundary layer of the intestine through which the fats would have to pass. This would have the effect of reducing the lipid uptake. It is also possible that since chitosan is a fibrous substance, it attracts the fats through its charge and absorbs them into a swelling ball of fats and fiber that is not only impermeable by the bile acids, but also passes through the intestinal tract unchanged and eventually excreted. In fact, there is not proof for any of these projected mechanisms, and all are theoretically possible. The fact is that it appears to work, but must be taken for several weeks for the effects to be noticeable. It is possible to lose weight by dietary fat absorption, and whatever mechanism is used by chitosan, it is well worth trying if you like your fatty foods but also want to lose weight. Combine chitosan with a good exercise regime and you might find that you can control your weight whatever you eat. Chitosan is available over the counter at any health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1650) Benefits - Supports joint function and tissue health* ![]() ![]() ![]()
Date:
December 11, 2006 03:46 PM
To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage. Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3 Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3 Promotes optimal joint comfort, function and flexibility* Boswellia serrata (Indian Frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4 Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7 Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8 Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11 Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results. Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption* Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14 Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability. Sustained Release – For lasting joint comfort and convenient dosing To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day. Safety Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.
Scientific References 2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149. 4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7. 5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146. 6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002. 7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5. 8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers. 9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46. 10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7. 11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308. 12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34. 13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232. 14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J. 15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1438) Pycnogenol: Heart, Blood Sugar and Cellular Health ![]() ![]() ![]()
Date:
November 03, 2006 12:16 PM
Pycnogenol (pronounced pic-nojen-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France. Pycnogenol® consists of particularly bioactive flavonoid species and its purity is in strict accordance with the United States Pharmacopoeia. Pycnogenol® was initially developed 35 years ago in Europe. During the past years it evolved as one of the most thoroughly researched nutritional supplements, with over 200 studies published in peer-reviewed journals. Seventy of these studies were clinical with in total more than 4,000 patients. Pycnogenol® taken in dosages from 25mg to 300mg is well tolerated and Pycnogenol® was attributed “generally recognized as safe” (GRAS) by the FDA. Pycnogenol® supports healthy capillaries The “Career” of Pycnogenol® began in Europe, where it was first used to maintain vein and capillary health. Pycnogenol® has been shown to strengthen blood vessel walls, with 15 clinical trials showing fast relief from ankle and foot discomfort. A recent study with 200 passengers on long-haul flights showed that Pycnogenol® taken before departure and again during the flight supports foot comfort and healthy circulation. Travelers typically comment that with Pycnogenol® it is much easier to put shoes on again upon arrival. Clinicians in Germany discovered that Pycnogenol® also supports healthy capillaries in the eyes. Retinal capillaries may be affected by imbalanced blood sugar levels. In a multi-center field study with 1169 subjects Pycnogenol® supported healthy capillaries in the retina and improved visual acuity to some extent. Pycnogenol® benefits the cardiovascular system More detailed investigation of the interaction of Pycnogenol® with blood vessel walls at the University of Florida, Tampa led to an amazing discovery. Pycnogenol® stimulates an enzyme in blood vessel walls that is responsible for generating the most important vascular mediator, known as “nitric oxide” (NO). NO triggers relaxation of the arteries and supports clear blood flow. Hence, NO is the body’s mediator for maintaining healthy blood pressure levels and circulation. NO plays such an important function for cardiovascular health that Dr. Louis Ignarro (UCLA) and his co-workers received the Nobel Prize for this discovery in 1987. A number of factors, including aging, can interfere with the body’s efficient production of NO. Supplementation with Pycnogenol® for four weeks was shown to restore NO production and improve blood supply to the fingertips of elderly people in a Japanese study. Microscopic evaluation of blood vessel diameter at the root of fingernails showed an increased diameter of capillaries allowing better blood perfusion. Specific sensors applied to the legs showed increased oxygen and decreased carbon dioxide presence. Better blood, nutrient and oxygen supply with Pycnogenol® benefits everybody. Italian researchers were able to show that regular intake of Pycnogenol® helps defy muscle cramps and minor pain in athletes. The relaxation of arteries has a favorable effect on blood pressure. In two clinical studies Pycnogenol® taken for at least eight weeks was found to significantly support normal blood pressure. Pycnogenol® stimulated NO generation directly translates into clear blood flow. This was first demonstrated at the University of Arizona, Tucson in smokers. Pycnogenol® dose-dependently, starting at a single dose of 25mg, countered the typical effects of cigarette smoking on the blood. Also, Italian vascular specialists found that Pycnogenol® supported the circulation of individuals on flights between New York and London. Pycnogenol® supports healthy blood sugar levels Pycnogenol® can support normal glucose levels when taken as part of a healthy diet and lifestyle plan. A clinical investigation has confirmed the significant glucose-lowering effect of Pycnogenol®. It was noted that Pycnogenol® did not affect insulin levels. Pycnogenol® appears to facilitate previously insulin-resistant cells to uptake sugar from the blood stream by yet unknown mechanisms. Pycnogenol® limits cellular irritation Two clinical studies carried out in Germany this year with student volunteers demonstrated that Pycnogenol® has a potent effect in preventing cellular irritation. Pycnogenol® inhibits a molecular “main-switch” in immune cells that triggers the onset of cellular irritation in any part of the body. Moreover, Pycnogenol® was found to inhibit so-called COX enzymes, which are involved with minor pain-sensation related to cellular irritation. Pycnogenol® sooths menstrual pain Japanese gynecologists discovered in 1999 that regular supplementation with Pycnogenol® soothes the normal discomfort of menstrual pain, particularly during cramping. Another clinical investigation of 47 women in year 2004 confirmed the effect of Pycnogenol® in addressing menstrual pain. This year a double-blind, placebo-controlled, multi-center field study with 116 women again confirmed these results. Pycnogenol® is not suitable for on-demand relief during menstruation. The studies show that Pycnogenol® reached highest efficacy when taken regularly for months. Pycnogenol® helps to support respiratory health Challenges to normal respiratory function may result from incidents the immune system perceives as harmful. Pycnogenol® offers valuable help in supporting respiration due to its immune-modulating effect and its ability to limit cellular irritation. A study at the University of Arizona found that Pycnogenol® supports clear breathing and lowers mediators of cellular irritation in the blood stream. More recently, a placebo-controlled clinical study at the University of California, Loma Linda described how Pycnogenol® supported healthy respiration in 60 children aged 6-18 years. Pycnogenol® needs to be taken continuously for prolonged periods of time for maximum benefit to the respiratory system. Pycnogenol® is investigated in clinical trials all over the world. New findings are posted on the website www.pycnogenol.com. Frank Schonlau Ph.D. is a biochemist who has spent nine years in medical research at the University Clinic of Munster Germany. His area of expertise covers vascular disorders, inflammation and dermatology. He has published more than 20 studies and review articles in the medical literature. Since entering the dietary field in 1999 he was involved in numerous studies on Pycnogenol® and communication of new health discoveries.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1414) An Interview with Congressman Sam Farr, Representing California’s Central Coast. ![]() ![]() ![]()
Date:
May 30, 2006 02:36 PM
Ambassador to Health Profile An Interview with Congressman Sam Farr, Representing California’s Central Coast. Congressman Sam Farr, a fifth-generation Californian, represents the state’s beautiful central coast. His district encompasses the length of the big Sur coastline in Monterey County, the Monterey Bay National Marine Sanctuary, the Salinas Valley “Salad bowl,” the redwoods, mountains and beaches of Santa Cruz County, and the majestic rural landscape of San Benito County. The health and wealth of this region has been strengthened by Rep. Farr’s focus on the environment, education and the economy. Rep. Farr was raised in Carmel, California and graduated from Willamette University with a BS in biology. He later attended the Monterey Institute of International Studies and the University of Santa Clara. He is fluent in Spanish. As a tough advocate for the health food industry, he has lobbied for strict federal organic standards. Todd: Congressman Farr, thank you for taking the time to speak with us! Id also like to thank you for all the great things you’ve done for our community, form funding marine sanctuaries and authoring the Ocean’s Act to expanding Pinnacles national Monument. The League of Conservation Voters and others have recognized you as an “Environmental Hero”. And, you’ve worked hard to support the economic vitality of central coast’s $3 billion agriculture industry which includes a substantial organic segment. Our backyard here is also the home of a robust group of nutritional supplement manufacturers. An estimated 187 million Americans are currently taking dietary supplements as part of their daily healthy diet. In California, we’ve got 792 natural product manufacturers and distributors. Where do you stand on the state of our industry? Congressman Farr: Well, thank you for the introduction and for asking to talk to me about nutritional supplement issues. I am very supportive of this industry and include myself in the 187 million Americans taking dietary supplements. I think supplements offer many safe and viable tools to maintain your health. The continued growth of this industry is an indication of both consumer confidence in the products and the products’ ability to fill the gaps where conventional medical care falls short. Todd: It is estimated that by 2030, more than 70 million Americans will be over the age of 65 and the cost of health care could reach $16 Trillion per year. A recent study by the Lewin Group showed that by taking certain dietary supplements, seniors can lead healthier, more productive, independent lives while saving billions in reduced hospitalizations and physician services. Do you share our view that a Wellness Revolution is needed to counter the dilemma of an aging population versus shrinking health care support in the future? Congressman Farr: Our health care system is definitely facing a challenge, especially as the Baby Boomers hit their 60’s and Americans are living longer than ever before. As a Baby Boomer myself, I am well aware of America’s aging population and the impact that will likely have not only on our social institutions but also our fiscal well-being. I agree that dietary supplements do play and will play an even larger role in the future as more seniors look for a way to augment their diets in order to stay healthy and active longer than past generations. Todd: Our industry is regulated by DSHEA (the Dietary Supplement Health and Education Act), which was passed unanimously by Congress in 1994 to create a reasonable regulatory framework for access to, information about, dietary supplements. But many say that the FDA and DSHEA weren’t adequately funded to do the job as tasked. “Supplements are unregulated” is a false argument we sometimes hear. To ensure that the FDA is able to carry out the law as Congress intended, Representatives Dan Burton (R-Ind.) and Frank Pallone (D-N.J.) introduced H.R. 2485, the DSHEA Full Implementation and Enforcement Act of 2005. Did you support this bill and where does it stand today? Congressman Farr: I think the DSHEA is a critical law and was proud to support it when Congress considered it in 1993 and 1994. I would certainly support H.R. 2485 if it came up for a vote in Congress. Unfortunately this bill has not moved since it was first introduced and referred to the Subcommittee on health in the house energy and commerce committee. Since this is an election year we have a tight schedule with only about 60 legislative days scheduled before we adjourn. That means it’s likely Congress will only finalize bills such as the appropriation bills that fund government before adjournment. Todd: Our business climate has included some valid and rigorous challenges to improve our industry, from good manufacturing practices (GMP), to allergy labeling, to implications of Prop-65 in California. It’s disconcerting that a new bill, H.R. 3156 The Dietary Supplement Access and Awareness Act would try to capitalize on misconceptions about the industry. In an era of declining health care and declining insurance coverage, this bill would regulate supplements as prescription drugs. Among other things, it would also require adverse event reports to be turned over to the FDA, even though other foods, including those with identical ingredients, do not have the same requirements. This has the potential to be the next Prop-65-like Lawsuit mill. The result of H.R. 3156 would be chilling. It will knock smaller producers out of the market. It will result in higher prices for all supplements. It will decrease the availability of health-giving supplements to the public. What’s your feeling on this? Congressman Farr: I am similarly concerned about H.R. 3156 and would oppose it if it came up for a vote in Congress. Like H.R. 2485, this legislation has been referred to a subcommittee on Health in the House Energy and Commerce Committee without any further action. The supplement industry has worked in good faith with the FDA since passage of DSHEA and H.R. 3156 would re-invent a wheel that isn’t needed. Instead, adequate funding as proposed in H.R. 2485 would provide ample oversight for the industry. Todd: According to a recent study, 72% of the general population believe the government should fund more research on health benefits of nutritional supplements. Do you agreen and what can be done to meet this need? Congressman Farr: I definitely agree that the federal government should play a bigger role in support of research regarding the health benefits of nutritional supplements. As a member of the House Appropriation Committee, I sit on the subcommittee that has jurisdiction over the FDA’s budget and I know the tight fiscal restraints the agency is under. I’ve worked with my colleagues to provide adequate funding, but it’s an uphill battle especially when we’re in a “robbing Peter to pay Paul” kind of situation. I recommend that people within the industry organize and use your consumer base to actively lobby Congress for additional funds. I’m fond of reminding people that the squeaky wheel gets grease – so let every Congress member and Senator know how much this issue matters to you. Todd: When there is overwhelming scientific evidence that nutritional supplements provides relief for a disease condition, it currently takes a lawsuit to get the FDA to relent and allow the claim. Even then, the FDA strictly limits the claim and requires a disclaimer that does more harm than good in communicating this important information to the public. There is a new bill, H.R. 4282, The Health Freedom Protection Act that would end FDA and FTC censorship of health information. As an example, the 50% of all adult males who suffer from an enlarged prostate could receive relief from that condition by consuming a simple and safe ingredient, saw palmetto derived from the fruit of the dwarf American palm tree. The FDA censors that information. The public deserves a better opportunity to be informed about omega-3 EFA and heart disease, folic acid and birth defects, phosphatidylserine and cognitive impairment. Do you agree and do you support this bill? Congressman Farr: I agree the public needs to access to the best information possible so they can make well informed choices about their health. I likely would support H.R. 4282 if it came up for a vote in Congress. Unfortunately this bill is in a similar situation as other we’ve mentioned in this interview – and again because of the tight schedule of an election year, it’s unlikely action will happen this year. Todd: According to the barometer study, 85% of the US population is currently using some type of dietary supplement. Do you? Looking at your busy schedule from co-chairing the House Oceans Caucus to your seat on the Travel and Tourism Caucus, you are one busy congressman! Are you popping nutritional supplements please tell us! Congressman Farr: I do take some nutritional supplements, though they vary and since Ginkgo Biloba isn’t among them I cant remember their names off-hand! One product I do use faithfully is Airborne to help me combat germs and colds that I might get from sitting on an airplane. But, like many Americans my life is over-scheduled and combined with the amount of air-travel I do, I find nutritional supplements helpful as I try to stay healthy despite my hectic lifestyle. Todd: Thank you Congressman Farr! Live long and prosper!
DSEA Release of Health/Cost Impact Study Conducted by the Lewin Group, Initial Results, Wash DC; Nov. 2, 2005 NNFA database. Adam.F on 3-15-06. DSEA Nutritional Supplement Barometer Study, 2005 Report, Prepared by the Natural Marketing Institute (NMI). Todd Williams; Source Naturals Marketing Programs Manager.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1288) Tru-E Bio Complex ![]() ![]() ![]()
Date:
December 08, 2005 04:58 PM
Tru-E Bio Complex TMNeil E. Levin, CCN, DANLA 7/27/05LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements. NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32 Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32 This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7 Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13 ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols. All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU). Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet. Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market. We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32 Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23 SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal. SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds CAUTIONS: None. SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient. GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. REFERENCES:
1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1000) Benfotiamine raises the blood level of thiamine pyrophosphate (TPP) ![]() ![]() ![]()
Date:
August 02, 2005 03:52 PM
Benefits Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine.4 Thiamine and its Co-enzyme, TPP Thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically-catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name "thiamine diphosphate." In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as "active acetate." Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle (citric acid cycle). The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called "oxidative decarboxylation," and for this reason, TPP was originally referred to as "cocarboxylase." TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below. Benfotiamine and Glucose Metabolism Benfotiamine normalizes cellular processes fueled by glucose metabolites. As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the Krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.5 In the presence of elevated glucose levels, the electron transport chain, the final ATP-generating system in the mitochondrion, produces larger than normal amounts of the oxygen free radical "superoxide." This excess superoxide inhibits glyceraldehyde phosphate dehydrogenase (GAPDH), as key enzyme in the conversion of glucose to pyruvic acid, resulting in an excess of intermediate metabolites known as "triosephosphates." Increase triosephophate levels trigger several cellular mechanisms that result in potential damage to vascular tissue. Cells particularly vulnerable to this biochemical dysfunction are found in the retina, kidneys and nerves. Benfotiamine has been shown to block three of these mechanisms: the hexosamine pathway, the diaglycerol-protein kinease C pathway and the formation of Advanced Glycation End-poducts. As discussed below, benfotiamine does this by activating transketolase, a key thiamin-dependent enzyme.6 Benfotiamine stimulates tranketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.* Transketolase diverts the excess fructose-6-phosphate and glyceraldehydes-3-phosphate, (formed by the inhibition of GAPDH, as mentioned above), into production of pentose-5-phosphates and erythrose-4-phosphate and away from the damaging pathways. Benfotiamine activates transketolase activity in bovine aortic endothelial cells incubated in glucose.6 To test benfotiamine’s ability to counteract these metabolic abnormalities caused by elevated blood glucose, studies have been done in diabetic rats. Benfotiamine increases transketolase activity in the retinas of diabetic rats, while concomitantly decreasing hexosamine pathway activity, protein kinase C activity and AGE formation.6 Benfotiamine and Protein glycation Benfotiamine controls formation of Advanced Glycation End-products (AGEs). AGEs have an affinity for proteins such as collagen, the major structural protein in connective tissue. AGEs are formed through abnormal linkages between proteins and glucose. This occurs via a non-enzymatic glycosylation reaction similar to the "browning reaction" that takes place in stored food.7 At high glucose concentrations, glucose attaches to lysine, forming a Schiff base, which in turn forms "early glycosylation products." Once blood glucose levels return to normal levels, the amount of these early glycosylation products decreases, and they are not particularly harmful to most tissue proteins. On long-lived proteins such as collagen, however, early glycosylation products are chemically rearranged into the damaging Advanced Glycation End-products. AGE formation on the collagen in coronary arteries causes increased vascular permeability. This vessel "leakiness" allows for abnormal cross-linking between plasma proteins and other proteins in the vessel wall, comprising vascular function and potentially occluding the vessel lumen. A number of other potentially harmful events may also occur, including production of cytokines that further increase vascular permeability. Endothelin-1, a strong vasoconstrictor, is over produced, increasing the possibility of thrombosis and generation of oxygen free radicals is stimulated.8 It is vitally important to support normal glucose metabolic pathways so that formation of AGEs is minimized. Benfotiamine, in the test tube (in vitro) prevents AGE formation in endothelial cells cultured in high glucose by decreasing the glucose metabolites that produce AGEs.9 Endothelial cells make up the membranes that line the inner walls of organs and blood vessels. In a rat study comparing the effects of Benfotiamine with water-soluble thiamin, Benfotiamine inhibited AGE formation in diabetic rats while completely preventing formation of "glycooxidation products," which are toxic by products of chronic elevated blood glucose. AGE levels were not significantly altered by thiamin.10 Benfotiamine also normalized nerve function in the animals. After three months of administration, "nerve conduction velocity (NCV)," a measure of nerve function, was increased by both benfotiamine and thiamin; at six months, NCV was normalized by benfotiamine, whereas thiamin produced no further increases in this parameter. Dysfunctional glucose metabolic pathways leading to AGE formation occurs in endothelial cells of the kidneys. In a recent animal study, benfotiamine was administered to rats with elevated glucose levels. Benfotiamine increased transketolase activity in the kidney filtration system of these rats, while at the same time shifting triosephophates into the pentose pathway and preventing protein leakage.11 Safety Benfotiamine has an excellent tolerability profile and can be taken for long periods without adverse effects.3,12 The statements in this fact sheet have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1. Bitsch R, Wolf M, Möller J. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab 1991;35(2):292-6. 2. Schreeb KH, Freudenthaler S, Vormfelde SV, et al. Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4):319-20. 3. Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther 1996;34(2):47-50. 4. Frank T, Bitsch R, Maiwald J, Stein G. High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. Eur J Clin Pharmacol. 2000;56(3):251-7. 5. Pike RL, Brown ML. Nutrition, An Integrated Approach, 3rd Ed. New York:MacMillan; 1986:467. 6. Hammes H-P, Du X, Edlestein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic neuropathy. Nat Med 2003;9(3):294-99. 7. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci 1984;81(2):583-7. 8. Brownlee M. The pathological implications of protein glycation. Clin Invest Med 1995;18(4):275-81. 9. Pomero F, Molinar Min A, La Selva M, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol 2001;38(3):135-8. 10. Stracke H, Hammes HP, Werkman D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes 2001;109(6):300-6. 11. Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 2003;52(8):2110-20. 12. Bergfeld R, MatsumaraT, Du X, Brownlee M. Benfotiamin prevents the consequences of hyperglycemia induced mitochondrial overproduction of reactive oxygen specifies and experimental diabetic neuropathy (Abstract) Diabetologia 2001; 44(Suppl1):A39.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=721) Pain - Post Op and Relaxation ![]() ![]() ![]()
Date:
July 13, 2005 09:24 AM
Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR. "Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music. Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good. "These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization. Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz. On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed. Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery." Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill. ----------------------------- Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association. The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998. A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study. There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity. Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density. The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group. These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70. "We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research. "Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus. As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D. Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine. ----------------------------- Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds. "The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander. "When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the airway and can bring breathing to a halt." Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain. These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comparison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood. "This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added. ------------------------------ Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher. Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development. These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study. "We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University. Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery. The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page. "Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk." The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=599) Bio-Chelation ![]() ![]() ![]()
Date:
June 29, 2005 05:38 PM
Bio-Chelation* By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt In The Beginning The Bio-Chelated¨ process describes a proprietary cold extraction technique developed by Mr. Frank D'Amelio Sr., founder and owner of Nature's Answer¨, and well- respected author*. Long before Nature's Answer¨ was formed (early 1970's), Mr. D'Amelio was immersed in the study of botanical medicine, researching the various herbal texts including the national USP/N.F. (United States Pharmacopeia/National Formularies) dating back to the mid -1800's. (The USP/N.F. is a reference source that provides manufacturing standards and extraction techniques used to make herbal formulas; these standards were considered official prior to 1938.) This authoritative formulary discussed the use of plant parts such as leaf, stem, bark, flowers and roots. It recommended certain solvents known as "menstruums", in which plant parts were soaked in order to extract their active constituents. High heat was also often utilized to concentrate the extract. Mr. D'Amelio noticed that high amounts of solvents, usually alcohol, were often recommended, and that sediment would fall to the bottom (precipitate) in certain solutions. He began to investigate how he could offer the consumer potent herbal products made with very low heat, with minimum precipitation, and without a lot of alcohol! A Clue From Nature In working towards the goal of attaining a final botanical extract product with little alcohol, Mr. D'Amelio turned to Nature for the apparent answer. He realized that plants were composed of 80-85% water as well as some alcohols, fats, etc. If plants were able to keep the active constituents in solution and use them as needed mainly through water, not alcohol or other solvents, why couldn't he? Thus, he began a long, in-depth series of experiments with many different plants. Through rigorous research protocols and scientific testing, he discovered that the active constituents of some plants could be extracted using lower alcohol amounts with water and other natural solvents such as organic apple cider vinegar or vegetable glycerine. At other times, however, higher alcohol was necessary, such as when he was extracting volatile oils like menthol from peppermint. The experimentation process continued, with Mr. D'Amelio documenting the optimum menstruum combinations required for each plant to yield the maximum beneficial components. (Note that there are differences in alcohol. The alcohol consumed in wine and beer is derived through a natural fermentation process with no processing other than filtration. When distilled alcohol is added to an extraction, which some herbal manufacturers use, it effects the body in a more detrimental way; thus the development of the Bio-Chelation¨ process, which uses only organic alcohol). The Bio-Chelated¨ Method Is Developed As Mr. D'Amelio continued his experimentation with various plants and menstruums, his extraction processes became more refined, and eventually led to the development of the Bio-Chelated¨ method. The Bio-Chelated¨ method incorporates soaking for a period of time, using different menstruum ratios for different plants to optimize their therapeutic values. Furthermore, this procedure offers additional significant advantages when compared with other types of extraction processes commonly employed by competitors in the herbal industry. Bio-Chelation includes the use of "cold extraction", where the plant parts are extracted without being exposed to excessive amounts of heat. Cold extraction helps the herb maintain vital minerals and other trace elements in solution, thus enabling the herb to keep its Holistic Balanceª intact. (Holistic Balanceª means that extracts retain as many of the natural constituents of the original plant as possible.) In addition, the Bio-Chelated¨ process incorporates the use of an exclusive technique that removes much of the alcohol used during the menstruum soaking (maceration) phase, replacing it with vegetable glycerin instead. The resulting yield is an herbal extract that is either alcohol-free, or has a low alcohol content. (Both alcohol-free and low alcohol products from Nature's Answer feature vegetable glycerin only. Glycerin is used because it helps bind certain plant constituents, is natural to the body, is easily absorbed by the cells and has little insulin response. Only vegetable glycerin has been used since 1972. In addition, all alcohol used in Nature's Answer's low alcohol formulas is certified organic.) The Bio-Chelated¨ method was the first extraction process to yield a 12-14% alcohol extract in the herbal industry! Nature's Answer Stands The Test of Time Over the last quarter of a century (since 1972), the Bio-Chelated¨ cold extraction process has been painstakingly tested and proven to stand the test of time. Incorporating Mr. D'Amelio's proprietary cold extraction process in today's manufacturing procedures continues to yield a measurably superior product. One such example is Saw Palmetto from Nature's Answer¨, a product that is produced utilizing our Bio-Chelated¨ method versus the more expensive CO2 method. Our Bio-Chelated¨, cold extraction process yields a product that not only contains the same amounts of active constituents as the more expensive CO2 extracted product, but features a higher percentage of polyphenols, the compounds responsible for the herb's antioxidant properties. The end result is a Saw Palmetto extract that maintains its holistic balance! (Note that most prior successful studies done on Saw Palmetto utilized grain alcohol extracts which contained naturally occurring polyphenols; the CO2 extracted products do not contain polyphenols!) Although larger quantities of herbal products are now being produced as compared to the earlier experimental batches made by Frank D'Amelio, his founding corporate philosophy remains intact - combine the greatest care with the highest quality of raw material to create the ultimate herbal extract that works. After all, that's what it's all about, isn't it? Bio-Chelated¨..Another reason to count on Nature's Answer Without Question! Manufacturing Highlights:
State-of-The-Art Laboratory Manufacturing Equipment HPLC, UV, IR, GC/MS, LC/MS, TOC and Densitometer 316 Pharmaceutical Grade Stainless Steel or Glass Lined Extraction Vessels (instead of the inexpensive, more commonly used plastic or polyethylene extraction vessels; these vessels are porous and may contain microorganisms, residual plasticizers that are difficult to clean and could cross contaminate different batches of herbs) FDA Registered & Pharmaceutically Licensed cGMP and SOP Compliant Manufactured in the U.S.A. *Botanicals - A Phytocosmetic Desk Reference (1999), Botanical & Herbal Folklore (1974), The Botanical Practitioner (1978) Bio-Chelated¨ is a registered trademark of Bio-Botanica Inc.¨ Holistic Balanceª is a trademark of Bio-Botanica Inc.¨
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=536) Alcohol-Free Herbal Extracts ![]() ![]() ![]()
Date:
June 29, 2005 05:20 PM
Alcohol-Free Herbal Extracts By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Alcohol: The First Menstruum Liquid extracts are a time tested, effective delivery system for medicinal herbs. When choosing liquid extracts, read the label. You will usually see that they contain quite a bit of alcohol. Alcohol is used as a menstruum, or solvent that frees all of the constituents from the fiber and cellulose of the plant, so that the specific medicinal constituents we want become more bio-available to the body. Alcohol has traditionally been used as the menstruum of choice because it is one of the most effective solvents (materials used to pull out the constituents of the herb) that is both reasonably priced and not too toxic on the body. Most of the herbal extracts on the market today have an alcohol content between 30 to 70%. Bio-Chelation: A Revolutionary Concept In the 1970’s Mr. Frank D’Amelio Sr., CEO and founder of Nature’s Answer®, noticed that the United States Pharmacopeia (the text that was used as a formulary for herbal processing), recommended using high amounts of alcohol to extract active constituents from the plant. He began to wonder how he could offer consumers potent herbal products without a lot of alcohol. One clue from Nature that became apparent to him was the fact that plants themselves were composed of 80-85% water. Since plants were able to keep their active constituents in solution and use them as needed through the use of water, not alcohol or other solvents, why couldn’t he? He began a long, in depth series of experiments with many different plants. Through rigorous research protocols and scientific testing, he discovered that the active constituents of some plants could be extracted using lower alcohol amounts along with water and other natural solvents, such as organic apple cider vinegar. (Conversely, higher alcohol was necessary at times when volatile oils were being extracted such as menthol from peppermint.) The experimentation continued, as Mr. D’Amelio recorded the optimum menstruum combinations required for each plant to yield the maximum medicinal components. He further refined the process, eventually developing the proprietary Bio-Chelation® cold extraction method. The Bio-Chelation technique describes an exclusive process that removes much of the alcohol used during the menstruum, or soaking phase, and replaces it with vegetable glycerin, yielding extracts that are either alcohol-free, or have a low alcohol content. In addition, the alcohol used in any Nature’s Answer herbal extract product has the further distinction of being ‘organic’. The Bio-Chelation method yielded the first 12-14% alcohol extract in the herbal industry! The Alcohol-Free Advantage There are many reasons why people may not want to use herbs with high alcohol content. Some people dislike the strong taste of alcohol. Alcohol can stress a weakened or under-functioning liver in sensitive individuals, such as those suffering from allergies, environmental sensitivities, systemic candida, and/or a host of other health concerns. Furthermore, people in recovery from alcoholism cannot use alcohol. Finally, alcohol is not appropriate for young children. Nature’s Answer's alcohol-free extract formulas replace alcohol with natural vegetable glycerin because glycerin helps to bind certain plant constituents and is easily absorbed by the cells. Glycerin occurs naturally throughout the body. It also makes up a portion of the cellular membranes. This gives glycerin an affinity for the body, making it an excellent carrier for herbs. (Nature’s Answer only uses “vegetable glycerin” in their products.) Another advantage of using glycerin over alcohol is that glycerin serves to protect and preserve the potency of the herbal extract in the bottle over the life of the product longer than alcohol would. Since alcohol easily evaporates, it can lose its effectiveness as a preservative for the herbal constituents as the amount of the alcohol in the bottle decreases. Glycerin, due to its viscosity (thickness) aids in maintaining the freshness and potency of the herb for the life of the product. Finally, glycerin has the added advantage of acting as a sugar-free natural sweetener, thus making the taste of some bitter herbs more palatable. Nature's Answer®, the pioneer of the alcohol-free extraction process, is proud to offer a comprehensive line of both single herb extracts and combination herbal formulas that do not contain alcohol.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=534) Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story ![]() ![]() ![]()
Date:
June 29, 2005 09:51 AM
Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story The hoodia landscape has been unnecessarily clouded recently thanks to the misinformation circulating about concentrated extracts and socalled “100%” hoodia powder. Most of the information is highly subjective, with no studies whatsoever to support claims that socalled “pure” powder is more efficacious than 20:1 concentrated extracts. In fact, purporting to offer 100% hoodia powder is a dubious claim at best, with some groups offering little in the way of solid evidence that theirs is actually authentic Hoodia gordonii grown in South Africa and imported to the United States legally with proper permits. Propagating the false notion that “more is better” is a risky, uncertain gamble if you’re not precisely sure what exactly you’re getting more of! At Source Naturals, a trusted company with years of experience and demonstrated excellence in nutritional supplements, we believe that nothing tops quality assurance. Extraction – The Bottom Line Much of the misunderstanding surrounding hoodia extracts directly corresponds to a common misperception that the word extract is mutually exclusive to standardization – a method of extraction that isolates and removes a constituent part of an herb or botanical for use in supplements to control potency. Unfortunately the ambiguity of the term “extract” in relation to hoodia products has led to uninformed claims that hoodia extracts somehow contain less essential Hoodia gordonii plant parts, which is patently false, and underscores the inherent confusion as to how high-quality concentrated hoodia powder is actually produced. Simply put, many of the truly effective hoodia products on the market are, by their very nature, extracts – whether they claim to be or not. That is because the concentration process by which the whole parts of the hoodia plant become dried powder is an extraction. Calling it anything but an extract would be, Frankly, disingenuous. The Process Hoodia gordonii is a succulent containing excess moisture that needs to be removed in order to make an effective, concentrated powder. The process by which that moisture is removed to yield the powder is called an extraction. This process, however, is different from standardized extraction. This process does not remove a single component from the plant; rather it separates the water from the solid parts of the plant, making a concentrated powder for a more powerful, effective product. The End Result The raw materials used to make HOODIA EXTRACT have not been added to, nor have we attempted to specifically extract any constituent parts of the plant to regulate potency. What we have done is taken high-quality, authentic, certified material from one of the industry’s most respected suppliers of Hoodia gordonii and held it to our own high standards of Total Quality Assurance (TQA™) in making a supplement with 20 times more functional hoodia than had we ground the plant up water and all. By putting it through stringent testing procedures in our quality control lab we have assured our product’s quality and efficacy. The Hoodia gordonii we receive is carefully scrutinized; put through High Performance Thin Layer Chromatographic (HPTLC) analysis for authenticity, and microbiological screening for contamination, as well as other rigorous laboratory protocols. Quality = Results When you buy Source Naturals HOODIA EXTRACT, you can be assured that you’re not just getting an effective, natural dietary supplement, you’re getting part of an almost 25- year old tradition in providing quality products that support your good health. So before you buy into “more = better,” remember the Source Naturals edict: Quality = Results. Source Naturals – dedicated to excellence, committed to you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=517) Circulatory System Enhancer ![]() ![]() ![]()
Date:
June 25, 2005 11:52 AM
Circulatory System Enhancer An article by Frank Murray in the April 1989 issue of Better Nutrition says, “Dr. Huber and Kidd concur with other researchers that ginkgo biloba dilates the blood vessels, allowing greater blood flow to the tissues. It also provides better drainage of waste products, especially through arteries that have been partially blocked because of atherosclerosis.” The article goes on to discuss the fact that ginkgo also inhibits the clumping of blood platelets, which can contribute to heart and artery problems. When circulating platelets stick together on worn are as found on the walls of aging vessels, clots and blockages can form. Anytime this happens, heart attack and stroke are possibilities. Ginkgolides are unique twenty-carbon terpenes which inhibit PA F (platelet activating factor), which controls the formation of clots. PAF also plays an important role in other disorders such as asthma, shock, anaphylaxis, renal disease, graft rejection, CNS disorders and a number of inflammatory conditions. A Natural Vasodilator Ginkgo affects the lining of the blood vessels and acts to dilate them through a chemical constituent which stimulates the release of a certain factor. Tests have shown that ginkgo extract promotes better venous tone, which helps to clear the blood of toxic metabolites that collect when blood flow is diminished. Apparently Oriental herbalists used the ginkgo leaf for arterial circulatory problems. Blood vessels can constrict in cases of diabetes, Raynaud’s disease, gangrene, angina, and intermittent claudication. Ginkgo can help to relieve leg cramping by facilitating better circulation to the limbs. In addition, it increases the circulation of blood to the retina and can help to prevent macular degeneration. Concerning heart function, some studies suggest that ginkgo can help normalize heartbeat. Research has shown that ginkolide contained in ginkgo can be as effective as some pharmaceutical drugs in treating severely irregular heartbeats.8 Because ginkgo can effectively reduce blood cell clumping, it can help prevent some heart - related disorders such as congestive heart disease. Circulatory impairment is at “the heart” of cardiovascular disease and ginkgo specifically acts to enhance circulation. Se veral laboratory tests have found that ginkgo helps the heart contract more effectively after times of stress by reducing the formation of oxygen free radicals. This protective effect can help prevent damage to heart muscle which may become oxygen deprived.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=456) References ![]() ![]() ![]()
Date:
June 24, 2005 04:34 PM
References 1Claire Kowalchik and William H. Hylton, Editors, Rodale’s Illustrated Encyclopedia. (Emmaus, Pennsylvania: Rodale Press, 1987), 176. 2Louise Tenney, “Echinacea”, To day’s Herbs. ( Provo, Utah: Woodland Publishing, Vol. XIII, Number 1, 1993), 1. 3Family Guide to Na t u ral Medicine. ( Pleasantville, New Yo rk : Reader’s Digest, 1993), 303. 4Andrew Weil, MD, Natural Health, Natural Medicine. (Boston: Houghton Mifflin Company, 1990) 236. 5Gary Gillum, Editor, “Echinacea” To day’s Herbs. ( Provo, Utah : Woodland Books, Vol. I Issue 11, July, 1981), 1. 6PenelopeOdy, The Complete Medicinal Herbal. ( New York : Dorling-Kindersley, 1993), 53. 7Michael Murray, ND and Joseph Pizzorno, ND, Encyclopedia of Natural Medicine. (Rocklin, California: Prima Publishing, 1991), 58. 8V.H. Wagner and A. Proksch., “Immunostimulatory Drugs of Fungi and Higher Plants”, Economic Medicinal Plant Research . (1985), 1, 113-53. 9Louise Tenney, The Encyclopedia of Natural Remedies. ( Pleasant Grove, Utah: Woodland Publishing, 1995), 50. 10Ibid. 1 1Daniel B. Mowre y, The Scientific Validation of Herbs. ( New Canaan, Connecticut: Keats Publishing, 1986), 119. 12Murray, 59. 13Michael T. Murray, N.D.. The Healing Power of Herbs. (Rocklin, California: Prima Publishing, 1995), 100. 14J. Mose, “Effect of Echinacin on Phagocytosis and Natural Killer Cells”, Med. Welt. (1983), 34, 1,463-7. 1 5M. Stimple, A. Proksch, H. Wagner, etal., “Macrophage Activation and Induction of Macrophage Cytotoxicity by Purified Polysaccharide Fractions From the Plant Echinacea Purpurea”, Infection Immunity. (1984), 46, 845-9. 16Mowrey, 119. 17Ibid., 250 18Ibid., 119 19Ibid. 20Ody, 176 21Velma J. Keith and Monteen Gordon, The How To Herb Book. (Pleasant Grove, Utah: Mayfield Publishing, 1983), 29. 2 2Louise Tenney, To day’s Herbal Health. ( Pleasant Grove, Utah: Woodland Publishing, 1992), 60. 2 3Daniel B. Mow re y, Ph.D., Echinacea. ( New Canaan, Connecticut: Keats Publishing, 1995), 31. 24Ibid., 33. 25Ibid., 41. 26C. Steinmuller, J. Roesler, E. Grottrup, G. Franke, H. Wagner and Matthes Lohmann, “Polysacharides Isolated From Plant Cell Cultures of Echinacea Purpurea Enhance the Resistance of Immunosupproes Mice Against Systemic Infections with Candida Albicans and Listeria Monicytogens,” Int-J-Immunpharmacol. 1993, July: 15(5): 605-14. 27Ibid., 43. 2 8U. Mengs, C. Clare and J. Poiley, “Toxicity of Echinacea Purpurea. Acute, Subacute and Genotoxicity Studies , Arzneimittelforschung. 1991, Oct. 41(10): 1076-81. ADDITIONAL REFERENCES Becker, V. H. Against snakebites and influenza: use and components of echinacea angustifolia and e. purpurea.. Deutsche Apotheker Zeitung, 122 (45), 1982, 2020-2323. Buesing, K.H. Inhibition of hyaluronidase by echinacin. Arzneimittel- Forschung. 2, 1952, 467-469. Foster, S. Echinacea, Nature’s Immune Enhancer. Healing Arts Press, Rochester, VT., 1991. Hobbs, C. The Echinacea Handbook. Eclectic Medical Publications, Portland, Oregon, 1989. Keller, H. Recovery of active agents from aqueous extracts of the species of echinacea. Chemie Gruenenthal G.M.B.H., GER. Oct . 11, 1956, 950, 674. Kuhn, O. Echinacea and Phagocytosis. Arzneimittel - Fo rxchung, 3, 1953, 194-200. Mc Gregor R.L. The taxonomy of the genus Echinacea (Compositae). Univ. Kansas Sci. Bull. 48, 1968, 113-142.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=419) REFERENCES ![]() ![]() ![]()
Date:
June 22, 2005 09:57 PM
REFERENCES
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=401) Nothing to Sneeze At ![]() ![]() ![]()
Date:
June 18, 2005 08:41 AM
Nothing to Sneeze At by Carole Poole Energy Times, August 14, 2004 To many, nothing is more annoying than a persistent allergy. Runny nose, itchy eyes, hives, sneezing, coughing...Frequently, allergies seem to represent suffering with no end. When you are sensitive to something in your environment, often your only hope for relief appears to be to flee to an elsewhere that eludes the problematic, trouble-making allergen. Complementary measures are available that can lower your risk of allergic reactions. Heading off allergic reactions before they strike can help you enter a comfort zone that leaves nothing to sneeze at. Limit Your Antibiotics While people have always suffered allergies, today, many experts agree, allergies are on the rise. One possible explanation: antibiotics. For instance, research at the Henry Ford Hospital in Detroit demonstrates that kids who get antibiotics within six months of being born run an increased risk of being allergic to dust mites, ragweed, grass and animals. At the same time, if two or more cats or dogs live with them, they reduce their chances of allergies (Eur Respir Soc ann conf, 2003). " I'm not suggesting children shouldn't receive antibiotics. But I believe we need to be more prudent in prescribing them for children at such an early age," Christine Cole Johnson, PhD, says. "In the past, many of them were prescribed unnecessarily, especially for viral infections like colds and the flu when they would have no effect anyway." Dr. Cole's investigators found that by age 7, kids who got one or more rounds of antibiotics were: When antibiotics are necessary, they are crucial to quelling bacterial infections. However, if you or your children suffer colds or flus, diseases caused by viruses, antibiotics have no effect on your illness but could increase your chance of developing allergies. " Over the past four decades there has been an explosive increase in allergy and asthma in westernized countries, which correlates with widespread use of antibiotics and alterations in gastrointestinal (GI) microflora," says Mairi Noverr, a researcher on a study linking allergies to antibiotic use (104th Gen Meet Amer Soc Microbiol, 2004). "We propose that the link between antibiotic use and dysregulated pulmonary immunity is through antibiotic-induced long-term alterations in the bacterial and fungal GI microflora." While a lot of research needs to be done, it may help to fortify the probiotic, or good, microbes in your intestines with probiotic supplements. One study has shown that giving probiotics to pregnant women helped their children avoid allergic eczema, a skin condition (Lancet 2001; 357:1076-9). Green Tea Relief Research has demonstrated that various types of tea can produce a range of health benefits. Tea drinkers can add allergy relief to that list. Research in Japan demonstrates that for the allergy-oppressed, green tea may help them have nothing to sneeze at. In laboratory tests, scientist found that green tea contains a substance that blocks one of the immune cell receptors which is often a part of the allergic response. The substance, methylated epigallocatechin gallate (EGCG), is believed to have a similar effect in the real world (J Agr Food Chem 10/9/02). " Green tea appears to be a promising source for effective anti-allergenic agents," notes Hirofumi Tachibana, PhD, the study's chief investigator and an associate professor at Kyushu University in Fukuoka. "If you have allergies, you should consider drinking it." Traditionally, many people have consumed tea as part of their effort to suppress sneezes, coughs and itchy eyes caused by allergies. This experiment supports the evidence that green tea, in particular, has a reliable effect. According to Dr. Tachibana, green tea's anti-allergenic benefits have not been completely established, but tea apparently has the potential to be effective against allergens like dust, chemicals, pet dander and pollen. Tea Antioxidant EGCG has also been shown to be a very active antioxidant, helping to quell the destructive effects of the caustic molecules known as free radicals. Green tea is richer in EGCG than black tea or oolong tea (a type that falls between black and green). Although other research has demonstrated that EGCG offsets allergic responses in lab animals fed this substance, scientists don't completely understand why it works for allergies. Researchers theorize that EGCG restricts the production of histamine and immunoglobulin E (IgE), two substances secreted in the body as part of the chain of chemical reactions that lead to an allergic reaction, says Dr. Tachibana. This study shows, for the first time, that a methylated form of EGCG can block the IgE receptor, which is a key receptor involved in an allergic response. The effect was demonstrated using human basophils, which are blood cells that release histamine. As of now, nobody knows how much green tea you need to guzzle to have the best protection against allergies and, of the several varieties available, nobody knows which green tea is best. Outside of the US, green tea is the second most popular beverage in the world, right behind water. In the US, however, black tea is more popular than green. But the allergy sensitive should think and drink green. Stay Away from Diesels Those who are allergic to ragweed or pet dander usually know they should avoid the source of their allergies. But now scientists have found that, for many allergy sufferers, diesel exhaust can also worsen sneezes and wheezes. Scientists at two southern California schools have shown that about half of us have inherited a sensitivity to diesel pollution that can make our allergies significantly worse (Lancet 1/10/04). "[T]his study suggests a direct way that pollution could be triggering allergies and asthma in a large number of susceptible individuals...," says Frank D. Gilliland, MD, PhD, the study's lead author. Diesel exhaust particles are thought to act as destructive free radicals in the lungs, forming caustic molecules that damage lung tissue. This irritation can cause your immune system to create larger amounts of compounds that make you sneeze and wheeze more. The Antioxidant Advantage Antioxidants, scientists believe, can help defuse this damage and ease the body's allergic responses. The California scientists looked at two antioxidant enzymes the body makes to protect the lungs called glutathione S-transferase M1 (GSTM1) and glutathione S-transferase P1 (GSTP1). Only about five of ten people's immune systems can make all the effective forms of these enzymes. The rest of us lack this protection to some degree, and the immune system in about one in five people can't make any effective form of these enzymes. The research team found that people allergic to ragweed who lacked these antioxidant enzymes suffered more when they took in both ragweed pollen and particles from diesel pollution. Breathe Easier With C This research may help explain why many health practitioners recommend vitamin C, a potent antioxidant, to allergy sufferers. Vitamin C "prevents the secretion of histamine by the white blood cells, increases the detoxification of histamine and lowers the blood-histamine levels," says Sylvia Goldfarb, PhD, author of Allergy Relief (Avery/Penguin). Scientists continue to study the allergy conundrum. Meanwhile, sip a cup of green tea and shut the window before the next truck comes by.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=376) Fats: The Good, the Bad, the Ugly ![]() ![]() ![]()
Date:
June 14, 2005 11:18 AM
Fats: The Good, the Bad, the Ugly by Thomas Sherman Energy Times, October 15, 2004 We need fat to absorb vitamins, to keep our brains sharp, to survive. But not all fats are our friends. Find out which ones are the heroes and the villains in your diet. In a lot of cases health fads don't live up to their hype. But the case for consuming more good fats-the omega-3 fatty acids found primarily in fish, flax and hemp oils-is strong and growing stronger. As a nation we eat too little of these good fats, and our health would improve greatly if we relied a little less on the bad saturated fat in burgers, skipped the ugly trans fats in fries and indulged in more salmon and other seafoods. Fish and the Heart Need proof? A wealth of research supports fish oil's desirable effects, especially on heart health. While many people believe that heart disease is primarily a problem for men, women who have passed through menopause are just as susceptible to heart problems. " [Our] findings suggest that all women, and most likely men, would benefit from regular fish intake," says Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts University in Boston. "A tuna fish sandwich counts, as does almost any other type of fish that is baked, broiled, grilled, or poached." But she points out that fried fish, which is often cooked in hydrogenated oils, is not helpful. In research on more than 200 women, performed at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts, scientists found that the arterial blockages among women who dined on fish were less (and impeded blood flow less) than in women who hardly ever ate seafood. Fish was especially helpful for women who had diabetes, a disease that makes you more prone to heart and circulation problems (American Journal of Clinical Nutrition 9/04). These effects are important: Heart disease is the number one cause of death for women, and older women who suffer from diabetes are particularly susceptible. The number of people with diabetes has been increasing of late, mainly due to the fact that Americans are overweight. Right now about 18 million people have diabetes and another 20 million are expected to suffer this condition in the next four decades. " This study shows that following the current guidelines of eating at least two servings of any type of fish per week slows down the progression of heart disease in women with coronary artery disease (CAD), especially those who were also diabetic," says Dr. Lichtenstein, coauthor of the study. "We further found that eating one or more servings per week of fish that is rich in omega-3 fatty acids, such as tuna or other dark-fleshed fish, is equally effective." Dangerous disruptions in heartbeat, known as arrhythmias, may also be affected by fish oil. "[E]xperiments show that fatty acids from omega-3 fish oils are stored in the cell membranes of heart cells and can prevent sudden cardiac death or fatal arrhythmias," notes Alexander Leaf, MD, medical researcher and professor at Harvard University. Fat for Your Brain The right kind of fat is also crucial for the function of your nerves and brain tissue, which is 60% to 70% fat. Incorporating omega-3 fatty acids into those cells can help keep your brain firing on all synapses. It may lower your risk of Alzheimer's disease, an irreversible form of mental deterioration that kills 100,000 Americans a year. About a thousand people a day in the US are found to have Alzheimer's, and experts believe that over the next 40 years 14 million of us will be doomed to being enveloped by the mental fog this condition produces. Research indicates that our brains probably need omega-3 fats for protection against the kind of damage that causes our mental capacities to slip. Once Alzheimer's starts, deterioration accelerates because brain cells start losing these fats. In experiments performed at the David Geffen School of Medicine at UCLA (Neuron 9/2/04), scientists looked at how a lack of docosahexaenoic acid (DHA, one of the omega-3 fats found in fish), affected the cellular processes that lead to Alzheimer's. They found that the part of brain cells that receive signals from other brain cells, the receptors, are vulnerable to damage from chemical reactions that take place inside the cells. However, DHA offers antioxidant protection against this destruction. When brain cells were denied DHA, the cells' receptors suffered extra harm. But when fish oil was present, brain cells were protected. In addition, animals that received extra omega-3s were better able to learn and find their way through mazes. Greg Cole, PhD, senior researcher on this study and a professor of neurology at Geffen, says, "We saw that a diet rich in DHA, or docosahexaenoic acid, dramatically reduces the impact of the Alzheimer's gene [which made the animals more susceptible to Alzheimer's]. Consuming more DHA is something the average person can easily control. Anyone can buy DHA in its purified form, fish-oil capsules, high-fat fish or DHA-supplemented eggs." Fishes rich in omega-3s include salmon, halibut, mackerel, sardines and herring. Protecting Kids from Asthma A surprising benefit of omega-3s has been found in pregnant women and their newborns: Pregnant women with asthma who eat fish rich in omega-3s during their pregnancy lower their children's risk of asthma. Not just any fish will do. The study (American Thoracic Society International Conference 5/25/04) discovered that mothers who ate fish sticks during pregnancy doubled the asthma risk in their kids. " Fish sticks are deep-fried, and they contain omega-6 fatty acids, which encourage inflammation of the airways," says study co-author Frank Gilliland, MD, PhD, professor at the Keck School of Medicine at the University of Southern California. "Oily fish [like salmon and trout] contain omega-3 fatty acids, which appear to be anti-inflammatory, and lead to the reduced potential for developing asthma and allergies." The USC investigation showed that when women with asthma ate oil-bearing fish during pregnancy, the risk of asthma for their children dropped more than 70%. The more fish that mom consumed, the less likely her baby was to develop asthma. Unfortunately, the study did not find the same benefit in women without asthma. " A family history of asthma is a very strong risk factor for a child developing asthma," Dr. Gilliland says. "It appears that oily fish interacts with the genes involved in the predisposition to develop asthma, and somehow reduces the risk." Although most of us try to avoid accumulating unsightly fat around our hips, the right kind of fat plays an integral part in the functioning of our bodies and may even keep us alive. Fats don't get much better than that.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=344) Eat to Live - fruits and vegetables are more effective than foods like ... ![]() ![]() ![]()
Date:
June 14, 2005 10:38 AM
Eat to Live by Mary Menendez Energy Times, April 14, 2004 By now, most everyone with even a cursory interest in health knows that fruits and vegetables are more effective than foods like cheeseburgers at making your body more resistant to chronic diseases such as cancer. But beyond that generality, few people seem to know how to fine-tune their meals for the most anti-cancer bang per bite. Over the course of the lifetime of planet Earth, the plant world has devised and concocted a wealth of nutrients that can help your body fight off cancer. It's time to put them to work for you. Would you be interested in a tasty, quick way to cut your chances of certain types of cancer in half? The means to this desirable end are about as close as your refrigerator and your dining room table: All you have to do is cut open and eat a single orange every day. According to cancer research in Australia, adding that extra serving of citrus fruit to your diet every day, only once a day, boosts immunity enough to significantly lower your risk of some common cancers. " Citrus fruits [protect] the body through their antioxidant properties and strengthen the immune system, inhibiting tumor growth and normalizing tumor cells," says Katrine Baghurst, PhD, of the Commonwealth Scientific and Industrial Research Organization (CSIRO). According to Dr. Baghurst and her fellow researchers, oranges possess the most antioxidants of any fruit: more than 170 different phytochemicals. The protection you can get from oranges is due to their influence on immunity. Your immune system has the assigned task of protecting you against cells that can turn cancerous. Sixty of the chemicals in oranges are substances called flavonoids that can help the immune system fend off inflammation and tumors. Better Vegetables When Americans eat fruits and vegetables, they don't eat the ones with the most anti-cancer (or other) health benefits. Instead, we dine on the same so-so produce too frequently. If we want more health benefits from our veggies, we'd better look to expand our culinary horizons. " While people understand they should eat a variety of fruits and vegetables each day, they are not translating 'variety' in a way to capture health benefits, such as reducing their risk of developing chronic diseases," says Susie Nanney, PhD, acting director of the Obesity Prevention Center at Saint Louis University. " People aren't eating the fruits and vegetables that contain the most nutrients," warns Dr. Nanney. "People are quite Frankly confused about nutrition. I feel their pain." Unfortunately, Americans rely too often on iceberg lettuce, corn, apples, potatoes and bananas; a steady diet of that produce doesn't produce the same benefits as indulging in a wider variety of vegetarian foods. Dr. Nanney points out that the vegetables and fruits most effective at helping the body fight cancer are dark green leafy veggies, citrus (oranges, grapefruits), cruciferous vegetables (broccoli and cauliflower) and produce that has yellow or orange color. Making Dinner Plans Dr. Nanney's spectrum of desirable foods includes: Desirable Diet " When we look at how to get the most bang for your buck, the most power, it's by eating these other fruits and vegetables instead of the traditional choices," Nanney insists. Studies show that tomatoes, colored by a pigment called lycopene, may be particularly helpful in lowering men's chances of prostate cancer. For instance, research on about three dozen men with prostate cancer found that those taking supplements of lycopene and other tomato phytochemicals had smaller tumors and less spread of their cancers (Exper Bio and Med, 2002; 227: 881). The researchers conclude that "lycopene may have an antitumor effect and may be useful as an adjunct to standard treatment of prostate cancer, such as surgery, radiation therapy, hormones and chemotherapy. In addition, lycopene supplementation appears to have reduced the [spread of cancer within the prostate], suggesting that lycopene may have a role in the prevention of prostate cancer." In a study on African-American men, who suffer a higher rate of prostate cancer than other Americans, researchers also found that lycopene can limit the DNA damage that may presage cancer (Amer Chem Soc Meeting #222, 2001). " This study does not say that tomato sauce reduces cancer," cautions Phyllis E. Bowen, PhD, a nutritionist at the University of Chicago and lead investigator in the study. " It says that it reduces DNA damage that we think is associated with cancer." Tomato Consumption Other studies have confirmed the finding that men who eat tomatoes suffer less prostate cancer. And if you want the most anti-cancer benefit from tomatoes, better cook them. According to Rui Hai Liu, MD, Cornell assistant professor of food science, "[Our] research demonstrates that heat processing actually enhanced the nutritional value of tomatoes by increasing the lycopene content-[the] phytochemical that makes tomatoes red-that can be absorbed by the body, as well as the total antioxidant activity. The research dispels the popular notion that processed fruits and vegetables have lower nutritional value than fresh produce." Less Meat While you're making an effort to eat more of the colorful vegetables, you should also eat less fatty red meat and cut back on high-fat dairy foods, according to research from Harvard. In this study, which covered eight years and looked at the diets of more than 90,000 women, scientists found that those premenopausal women who ate the most fatty red meat and regular milk had the highest chance of developing invasive breast cancer. The scientists taking part in this study believe that eating more saturated fat from meat may increase hormone levels that boost the chances of breast cancer (Jrnl Natl Cancer Inst 2003;95:1079). In this research, the total amount of fat didn't affect cancer risk, but the amount of animal fat did. Women who ate the most red meat had a 54% higher chance of breast cancer. Aside from avoiding red meat, women who wish to lower their risk of breast cancer should also limit their consumption of alcoholic beverages. A study of two thousand post- menopausal women found that those who averaged about two drinks a day raised their risk of breast cancer by about 80% (Cancer Epidem, Biomarkers and Prevention, 10/03). Here, too, researchers believe that alcohol affects the level of hormones that influence cancer. The moral of the research into how food can slow cancer risk: Eat a wide variety of vegetables and fruits early and often. Limit meat and alcohol. Change the color of the fruits and vegetables on your plate for a better chance of a brighter future.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=340) Celebrity Holiday Fare - eating plenty of vegetables is the trendiest trend... ![]() ![]() ![]()
Date:
June 13, 2005 09:53 AM
Celebrity Holiday Fare by Claire Gottlieb Energy Times, October 11, 2003 Trendy celebrities and trendy food go together like holidays and sparkling trees. Within the celebrity-filled universe known as the media, eating plenty of vegetables is the trendiest trend. And, according to the latest nutrition research, it also may be the healthiest. Even before Frankenstein's monster picked up his first movie contract or endorsement deal, he was a vegetarian (for reasons best known by Mary Wollstonecraft Shelley, his creator). Meanwhile, well-known actor Woody Harrelson, a fan of raw, vegetarian foods, professes that his devotion to uncooked veggies only reached firm ground when he became convinced they could and would taste fantastic. The tastiness of the recipes we've included with our inspection of the rarefied world of celebrity food prove that the celebrity predilection for these dishes keeps taste buds happy. For Love of Pie When preparing your holiday fare this season, taking tips from the dietary habits and favored dishes of celebrities may perk up your lunches and dinners. Healthy dishes can be delicious! As Woody Harrelson points out in his foreword to Living Cuisine (Avery/Penguin) by Renee Loux Underkoffler, he became a fan of raw vegetables when he was convinced that they could be made into delicious dishes. "Though I wasn't raw at the time, I knew enough to know that raw food and its emphasis on enzymes being the life force of the food is the way to go for optimum health and energy. Still, you can talk theory all you want; if the taste isn't there, color me a cooked-food junkie." Eating dishes cooked by Ms. Underkoffler left him and Gabriel Cousens (a health book writer) speechless. "We were struck dumb by our taste buds...the coup de grace was one of Renee's coconut cream pies, which, I confess, almost brought Gabriel and me to blows over the last piece." Other celebrities also find Ms. Underkoffler's food preparation skills to be superb. Alicia Silverstone raves, "I love Renee....Her food reflects that spirit, opening the senses to everything around you-it's incredibly rich and delicious and full of health and restorative energy. Her food is medicine." (But it doesn't taste like it!) Birth of a Charitable Idea Meanwhile other celebrities have taken their food act to a whole new level. Consider how Paul Newman's holiday habits led to his food adventures. The story on Mr. Newman starts with salad dressing and Christmas. He and his friend, author A.E. Hotchner, originally created home made dressing and bestowed wine bottles of the stuff on family and friends for Christmas presents. Consequently, every holiday season Mr. Newman and his immediate family indulged in Christmas caroling and salad dressing giving. The demand for the dressing grew every successive holiday season until Mr. Newman and Mr. Hotchner decided to go commercial: Sell the dressing and make it available to shoppers throughout North America. The profits go to charity, and Mr. Newman bestowed about a million dollars to worthy causes in the first year. In the early 80s, the Newman's Own brand started out with its Oil & Vinegar Dressing. Today they offer salad dressings, pasta sauces, salsas, popcorn, lemonade and other sauces. According to Mr. Newman, the two principles that rule the company are an insistence on top-quality products without artificial ingredients or preservatives and the donation of all after-tax profits from the sale of the products to educational and charitable organizations, both in the United States and foreign countries where the products are sold. Over $125 million worth have been donated since 1982. In 1986, Mr. Newman founded The Hole In The Wall Gang Camp, along with Ursula Gwynne and A.E. Hotchner, with funds from Newman's Own and other donations. The camp, located in Connecticut, is for children with serious disease. (Newman recipes are available at the website: www.newmansown.com.) Whether the latest celebrity trend wends its way to raw food or cooked creations, you can safely count on the fact that celebrity heads will rest easy tonight (and yours can, too!) knowing that they've eaten food that's both in fashion and healthy. Leo Tolstoy, the celebrated Russian novelist, once pointed out, "Vegetarianism serves as a criterion by which we know that the pursuit of moral perfection on the part of man is genuine and sincere." When you try it for yourself, you'll find that serving mostly vegetarian meals may also offer evidence of a sincere devotion to better health and happier holidays.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=319) Mushrooms ![]() ![]() ![]()
Date:
June 10, 2005 10:16 PM
Mushrooms by Frank Sturges Energy Times, December 7, 1999 The interest in mushrooms as health enhancers has... mushroomed. Mushrooms, researchers have found, are filled with a long list of substances that may help us fight disease. Some of these natural chemicals boost immunity. Others may be effective against cancer and heart disease. One of the most remarkable aspects of the research into mushrooms stems from the vast number of mushrooms that dot the landscape. At least 1.5 million types of fungi populate forests, fields, nooks and crannies, but studies have detailed the properties of less than 3,000. Compound Interest One of the most important of these classes of compounds are the polysaccharides. Scientists believe these long starch molecules spark immune action that can protect us against invading germs or cancer. They may do this by persuading the body to create what are called killer T-cells. These immune warriors destroy microscopic invaders and may help stop tumors. According to Paul Stamets, author of Growing Gourmet and Medicinal Mushrooms (Ten Speed), use of polysaccharides... "will synergistically, in combination with the individual's immune system, result in dramatic recoveries...Right now we don't clearly understand all the elements in those formulas to be able to predict downstream what will happen. But clearly with some people, it is tremendously effective" (Townsend Ltr, 6/98). In addition, mushrooms also make biologically active chemicals called steroids and terpenes, says Christopher Hobbs, author of Medicinal Mushrooms (Interweave). These substances are thought to help fight off the formation of cancerous tumors. Maitake: Useful Fungus Maitake (Grifola frondosa) mushrooms, also known as "Hen of the woods," contain chemicals called beta glucans that can enhance immunity. Scientists are particularly fascinated by substances called the "D-fraction." Studies show these can spur immunity (Biol. Pharm. Bull. 17(12), Dec. 1994: 1554-60). Researchers are also looking into the possibility that Maitake can help people with AIDS regain weight. And scientists are examining their effect on high blood pressure and diabetes. Reishi's Effects In Tibet, the Reishi mushroom (Ganoderma lucidum) has long been used to battle altitude sickness in the Himalayan mountains. Reishi is also reputed to soothe frayed nerves. Scientific studies have supported these traditional uses, finding that people who consumed Reishi functioned better in low oxygen (Proceedings Contrib Symp 59 AB, 5th Intl Cong, 8/14-21, 101-104). Other research finds Reishi may help ease arthritis (Proc 1st Intl Symp on Ganoderma l. 11/17-18, 99-103, Tokyo). Lion's Mane Lion's Mane (Heri-cium erinaceus), also called "Monkey's head," has traditionally been a treatment for stomach problems in China. But researchers have found that chemicals in this mushroom help fight tumors (Biosci Biotech Biochem 56(2), Feb. 1992: 347-8). During the past few years, scientific investigators have also begun to extract chemicals called erinacines from lion's mane. These substances, (known as Nerve Growth Stimulant factor) appear to encourage neuron regeneration. The potential uses: boosting nerve performance, fixing neurological damage and treating Alzheimer's disease (Tetrahedron Ltrs 35(10), 1994: 1569-1572). Divine Fungus Known as Cogmelo de Deus (Mushroom of God) in Brazil, the Royal Agaricus (Agaricus blazei) has been grown in Japan since the '70s where it enjoys widespread popularity. Researchers find that it provokes powerful anti-tumor effects. This fungus harbors more beta-glucans, immunity enhancers, than other mushrooms. Mushroom Performance Can a fungus make athletes faster? A few researchers think so, pointing to Chinese Olympians who use Cordyceps sinensis. This fungus, traditionally grown on caterpillars, is another native of the Himalayas. Traditionally, Cordyceps has been used to foster stamina, better breathing and immunity. At least one study shows this fungus may help blood vessels dilate during exercise. By supplying extra blood to working muscles, Cordyceps may help fight off fatigue and boost performance (Abstracts from 5th Mycological Cong, Vancouver, 8/14-21). Research Extravaganza The mushroom called Shiitake has been the subject of an extravagant amount of research since the '60s. Called the "elixir of life," it boosts immunity. Stamets reports that people with cancer who take Shiitake do significantly better in coping with their disease (Abstract 2nd Meeting Soc of Natl Immunity, Italy, 5/25/94). Another characteristic of Shiitake mushrooms: a celebrated taste. The tongue and the palate take great pleasure in this health enhancer!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=285) Cross Training ![]() ![]() ![]()
Date:
June 10, 2005 02:48 PM
Cross Training by column Energy Times, April 1, 1999 If you've ever felt burned out, bored and/or just plain tired of your exercise program, you may be in need of a taste of cross training. When your exercise routine becomes too routine, you run not only the risk of losing your motivation for physical activity, but you may also run an added chance of injury. The possible cause: overusing particular muscles that receive an excessive amount of stress as other muscles practically atrophy while waiting for a chance to show off their stuff. For instance, if you are a devoted runner who spends hours jogging, your upper body may wither unless you give it a reason not to. At the same time, your achilles, hamstrings, knees and lower back muscles may protest those miles after miles. As Frank Jobe, MD, Neal EllAttrache, MD, and Karen Mohr, PT, point out in Athletic Forever (Contemporary), "Dedicated runners are among the most injury-prone of all athletes. If running is your main form of exercise, you have a 37 to 56 percent chance of sustaining an injury each year and your chances for a recurrence of that injury are as high as 70 percent." Simple Principle The basic principle of cross training is simple: take part in various activities that supplement each other. Runners should lift some weights or at least shoot a few hoops to keep those arms and shoulders toned. Bikers should walk or run now and then to keep their bones healthy. (Bicycling, since it is not a weight bearing exercise, does little to promote bone strength.) Swimmers should find something to do on dry land so that their bones react to gravity and grow stronger. And, no matter what your sport, you should stay well-nourished and supplied with plenty of antioxidants. As Stephen T. Sinatra, MD, points out in Optimum Health (Bantam), while athletes may enjoy health benefits from exercise, "The vigorous training pursued by competitive athletes renders them more prone to catabolic stress-a situation in which tissues are constantly broken down." He goes on to point out that the low fat diet many athletes follow may be short of antioxidant nutrients. Unfortunately, that shortage can lead to injury. The metabolic acceleration caused by athletic activity may increase potentially harmful oxidative stress at the cellular level. Without antioxidant nutrients to help quell that stress... Well, the results may not be pretty. Potentially, that kind of oxidative damage may, theoretically, lead to cancer or heart disease. As Dr. Sinatra says, in those circumstances, "the supplemental use of glutathione, vitamins C and E, coenzyme Q10 and magnesium seems reasonable. Some athletes, such as menstruating women, may also need iron supplementation." In addition, water is crucial for athletes to stay adequately hydrated during activity. According to Daniel Gastelu and Fred Hatfield, PhD, in Dynamic Nutrition for Maximum Performance (Avery), when you run short of water "this can adversely affect performance and, in the long run, can cause peaks and valleys in the athlete's performance." In addition, they advise using sports drinks to stay adequately supplied with electrolytes. "The major electrolytes found in bodily fluids are chloride, magnesium, potassium and sodium." Electrolytes serve a host of duties, including keeping the heart muscle functioning properly. Gastelu and Hatfield explain, "An electrolyte is an ion that is required by the body to regulate the electric charge and flow of water between the cells and the bloodstream." Getting Better All the Time Even if you cross train religiously and try to avoid overdoing one particular sport, sooner or later you may incur injury. If you do (or even before you hurt yourself), the trio of Stanley W. Jacob, MD, Ronald M. Lawrence, MD, PhD, and Martin Zucker, authors of The Miracle of MSM (Putnam), believe that methylsulfonylmethane (MSM) can provide reliable relief for pain and suffering. "Many people experience rapid relief after starting MSM," say this trio. They go on to claim that "this nutritional supplement has real potential to make a significant impact on the quality of life." "Your main enemy in the hours following an injury is inflammation," warns Athletic Forever. For injury, they recommend RICE: rest, ice, compression and elevation. In other words, put the injured body part in a firmly wrapped bandage (don't cut off the circulation!) Keep the injury cold but don't put ice directly on it (watch out for frost bite). Rest a while and keep the injury elevated. Then, don't exercise again until you've fully recovered.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=267) Cholesterol Conundrum ![]() ![]() ![]()
Date:
June 10, 2005 02:35 PM
Cholesterol Conundrum by Jane Lane Energy Times, February 7, 1999 The cholesterol story packs enough subplots to satisfy a soap opera. There's Cholesterol: The Good, the Bad and the Awful. Cholesterol: The Stalker Behind Every (Restaurant) Door. Cholesterol Steals Your Heart Away-to the Mediterranean. The very image of cholesterol chills the imagination. Lurid and unsavory, it would seem to bob through the bloodstream like blobs of fat congealed on cold soup, slathering itself onto arteries. Cholesterol is in fact a normal, natural substance in our bodies, found in the brain, nerves, liver, blood and bile. Cholesterol is so crucial that each cell is equipped with the means to synthesize its own membrane cholesterol, regulating the fluidity of those membranes when they are too loose or too stiff. We manufacture steroid hormones-the female hormones estrogen and progesterone, and the male hormone testosterone-from cholesterol. Adrenal corticosteroid hormones, which regulate water balance through the kidneys, and the hormone cortisone, the vital anti-inflammatory that also governs our stress response, come from cholesterol. Other jobs of cholesterol: production of vitamin D and bile acid (for the digestive process); healing and protecting skin, and antioxidant compensation when vitamin and mineral stores are low. How can mere mention of this invaluable component in our body chemistry make our blood run cold? Guilt by Association Cholesterol's reputation as a bad character actually originates in the crowd it runs with: the lipoproteins, protein molecules to which it binds in order to travel back and forth through the bloodstream to the liver, where it is manufactured. Not really a nasty round glob of fat at all, cholesterol is a crystalline substance, technically a steroid, but soluble in fats rather than water, thus classified as a lipid, as fats are. Thousands of cholesterol molecules bind with lipoproteins, spherical fat molecules that transport them through the bloodstream. Three different kinds of lipoproteins participate in this necessary process, not always with the same salutary effect. Here's how they work: High-density lipoprotein (HDL): referred to as the "good cholesterol." Carries relatively little cholesterol. Travels through the bloodstream removing excess cholesterol from the blood and tissues. HDLs return the surplus to the liver, where it may once again be incorporated into low-density lipoproteins for redelivery to the cells. Low-density lipoprotein (LDL): the so-called "bad cholesterol," heavily laden with cholesterol, hauling it from the liver to all cells in the body. Ideally, this system should be in balance. But if there is too much cholesterol for the HDLs to pick up, or an inadequate supply of HDLs, cholesterol may aggregate into plaque groups that block arteries. Lipoprotein(a), or Lp(a): the "really bad" cholesterol, can step in, providing the glue that actually sticks to the arterial wall. Lp(a) is an LDL particle with an extra adhesive protein wrapped around it, enabling it to attach fat globules to the walls of blood vessels. The potentially deadly results are atherosclerotic ("plaque") deposits. Simple LDL lacks adhesive power and presents little risk for cardiovascular disease. Researchers confirmed the existence of Lp(a) in the August 1996 issue of the Journal of the American Medical Association, disclosing that high levels of Lp(a) in the blood can double a man's risk of heart attack before age 55. Doctors estimate that about 20% of all Americans carry elevated levels of Lp(a). One troubling aspect of the report, part of the ongoing 40-year-old Framingham Study, concerned the fact that the men who suffered heart attacks entered the project with no signs of heart disease and only slightly elevated cholesterol. But during the 15-year investigation, 129 men out of 2,191 developed premature heart disease. The culprit? High levels of Lp(a) Experts don't know for certain where Lp(a) comes from, or its normal function, although they suspect the body's quotient of Lp(a) is mostly due to your genes. According to the study, they also believe that aspirin, a blood thinner, and red wine (or its grapeseed and skin extracts) may mitigate the damage of Lp(a). That also would explain why the French, who tend to wash down their fat-rich diet with red wine, experience a relatively moderate incidence of cardiovascular disease The Terrible Triglycerides The body also transports fats via triglycerides (TGs), the main form of body fat and the storehouse for energy. Edible oils from seeds, egg yolk and animal fats also are composed chiefly of TGs. Although not as corrosive as LDL, excess TGs intensify heart disease potential when they oxidize and damage artery linings or induce blood cells to clump. An "acceptable" level of triglycerides is thought to be 200 milligrams, although under 150 is probably healthier. And some researchers think your triglyceride reading should be below 100. High triglycerides and low HDL often occur together, increasing the risks of cardiovascular disease, high blood pressure, heart and kidney failure and other degenerative diseases. What To Do About Your Cholesterol Have it checked. High cholesterol alone shows no symptoms. Your health practitioner can perform a laboratory test to measure your levels. Thoroughly share your own medical history and as much as you know about your family members: heredity and related illnesses definitely are important influences. People with diabetes, for example, can have high levels of triglycerides, which also may lead to pancreatitis (painful inflammation of the pancreas) at extremely high levels. According to the National Cholesterol Education Program, a reading of under 200 mg/dL is desirable; 200 to 239 is borderline high; 240 and above is high. Your LDL level should be 130 or under; HDL should not be lower than 35. A triglyceride level below 200 is considered desirable; readings above 400 are high. Adjust your diet. Cholesterol levels are readily controllable, primarily through changes in your diet. Leslie C. Norins, MD, PhD, suggests all-out war in his Doctor's 30-Day Cholesterol Blitz (Advanced Health Institute) with saturated fats, which raise cholesterol more than any other component in your diet, as your number-one target. Out with saturated fats like butter, cheese, whole milk, ice cream, red meat and some vegetable fats found in tropical oils like coconut and palm; in with fruits, vegetables, brown rice, barley (a good source of soluble fiber, the kind that soaks up fats and cholesterol and escorts them out of the body), beans, potatoes and pasta, prepared or dressed with monounsaturated fats in olive and canola oils (the so-called Mediterranean diet concept). Feast on cold-water fish (mackerel, salmon, sardines and herring) rich in omega-3 fatty acids that help reduce serum lipids, among many other healthful advantages. Exercise. Move it and lose it are the words to live by when it comes to cholesterol. Researchers from the Stanford Center for Research in Disease Prevention reported in the July 2, 1998 New England Journal of Medicine (vol. 339, pages 12-20) that a weight-loss diet like that of the National Cholesterol Education Program plus exercise significantly lowered LDL (bad) cholesterol levels for men and postmenopausal women. The diet alone failed to lower LDL in these folks with high-risk lipoprotein. Educate yourself. In addition to your health practitioner, books and magazines can guide you in cholesterol management. A trove of information is the National Cholesterol Education Program (NCEP), launched in 1985 by the National Institute of Health. Their address is: National Cholesterol Education Program, Information Center, P.O. Box 30105, Bethesda, MD 20824-0105; telephone (301) 251-1222; they're on the web at /nhlbi/. Recommended Reading: Fats that Heal, Fats that Kill (Alive, 1993), by Udo Erasmus. Prescription for Nutritional Healing (Avery, 1997), by James F. Balch, MD, and Phyllis A. Balch, CNC. The Healthy Heart Formula (Chronimed, 1997), by Frank Bary, MD. Eradicating Heart Disease (Health Now, 1993), by Matthias Rath, MD.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=266) Intimate Response - The Freedom to Change. Boost intimacy ![]() ![]() ![]()
Date:
June 02, 2005 12:48 PM
SENSUALITY AND MENOPAUSE. FOR MANY WOMEN THIS apprehensive milestone is foreshadowed by disquieting physiological changes. Its debut marks a transition period that can actually begin at age 40. Called pre-menopause, it usually lasts 3 to 6 years and is characterized by powerful hormonal changes with wide-ranging effects on a woman’s body. Her level of romantic passion is often influenced by these changes. Source Naturals is proud to announce ETERNAL WOMAN™ INTIMATE RESPONSE™. This herbal-safe, natural formulation may support a woman’s healthy vitality and vigor during pre-menopause. Healthy Circulation = Natural Vitality. Most women experience decreases in desire at one time or another. Activity levels, monthly hormonal changes, circulatory status, drugs such as oral contraceptives and anti-depressants, alcohol and emotional factors all may contribute to a woman’s passion. However, premenopause is something more. Hormones stimulate, affect and balance hundreds of processes during a woman’s monthly cycle. When their levels begin to fluctuate and decline during premenopause, the body’s internal balancing act is acutely influenced. The bloodstream is our “river of life” as it delivers oxygen and nutrients throughout the body. Maintaining adequate blood circulation is necessary to our health and vitality. INTIMATE RESPONSE contains these supportive herbs and nutrients: yohimbe, epimedium, Ginkgo biloba, Panax ginseng, and L-Arginine. The Nitric Oxide Connection. L-Arginine is the primary amino acid t hat the body uses to make nitric oxide. It is nitric oxide that helps the muscle tissues surrounding a blood vessel to relax, allowing more blood to flow to the organs. Panax ginseng is a highly valued botanical traditionally utilized as an energizing tonic. In use for thousands of years in China, its main active constituents are the ginsenosides. Ginkgo extract is traditionally the premier herb for supporting blood flow in the circulatory system. Pregnenolone is the starting point from which all sex hormones are produced internally. Yohimbe is an African herb that has traditionally been used for more than 100 years. It supports peripheral blood vessels. Epimedium and dong quai are highly valued blood tonic herbs in traditional Chinese medicine used to support circulation and “life essence.” Vitamin B6 and folic acid support proper blood flow and healthy arteries by reducing levels of homocysteine in the bloodstream. The Healthy, Herbal-Safe Response. INTIMATE RESPONSE is a remarkable combination of herbal-safe, gentle ingredients that may support healthy and normal circulation during pre-menopause. For the freedom to change™ naturally...choose INTIMATE RESPONSE by Source Naturals.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=159) Genistein 1000mg Eternal Woman - Soy Supplement ... ![]() ![]() ![]()
Date:
June 02, 2005 10:30 AM
For most of human history, we existed in a world that was very different from the one today. Our endocrine systems evolved in an environment without synthetic chemicals. Unfortunately, today we’re surrounded by artificial hormone-mimicking compounds that disrupt the subtle biological processes that determine growth and reproduction. Receptors on our cells meant to receive natural bodily hormones can also accept molecules other than the ones they were intended to receive, placing our endocrine systems under considerable duress. Fortunately, certain plants contain estrogen-like compounds that are also accepted by hormone receptors in the human body – but with beneficial effects. Soybeans, which contain the isoflavone Genistein, can help regulate and maintain normal menstrual cycles and menopausal transitions. Source Naturals GENISTEIN is a concentrated form of the essence of the soybean. The Secret of Soy Not surprisingly, it was Ben Franklin who first introduced America to soybeans. Always on the lookout for beneficial imports, he was intrigued by the soybean cheese he saw in England. Today, tofu and other soy products are gaining popularity here in the West, in good part due to the reported benefits to populations that consume a considerable amount of soy products. Some researchers have postulated that the high intake of soy foods by Asians may be a key factor in their low incidence of certain health problems that are common in the West. For example, epidemiological studies show that women in Asia have a higher occurrence of normal trouble-free menopause. There is no Japanese word for hot flashes. Soy foods contain high concentrations of phytonutrients including phytosterols and isoflavones. Isoflavones are an important class of bioflavonoids whose properties have been well researched. Of the seven isoflavones contained in soybeans, the most active are genistein and daidzein. Source Naturals GENISTEIN contains over 11 mg of genistein, 42 mg of daidzein, and 86 mg of total isoflavones per four 1000 mg tablets. Genistein and Estrogen The subject of scientific studies since 1966, genistein research has been published in many journals including the American Journal of Clinical Nutrition and the Annals of the New York Academy of Science. Genistein has been shown to bind to the same receptor sites as estrogen. This helps to maintain normal menstrual cycles and menopausal transitions. By competing for human estrogen receptors, genistein causes excess estrogen to be sent to the liver for elimination. Conversely, when there is too little estrogen (the situation during menopause), phytoestrogens – genistein and daidzein – substitute for the lack of human estrogen, mitigating the effects of its absence. Genistein and Cell Growth One of genistein’s most promising functions is its ability to inhibit capillary proliferation. By neutralizing a growth factor called vascular endothelial (vegF), genistein protects cells. Genistein also shows pronounced inhibition of tyrosine kinase, the enzyme that interferes with normal cell growth. Soybeans are the only significant dietary source of genistein; however, the amount of soy foods necessary to meet the body’s needs can be difficult to incorporate into today’s diet. In Asia, the daily intake can be up to 20 times that of a Western diet. Source Naturals GENISTEIN is made from the germ of isoflavone-rich soybeans, using a chemical- free process that yields a consistent standardized isoflavone content. It requires approximately 400 pounds of soybeans to yield just one pound of finished product. With GENISTEIN, Source Naturals brings the remarkable properties of a time-honored food plant into your wellness program today.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=149) Guggul – New Benefits for Heart Health ![]() ![]() ![]()
Date:
May 11, 2005 09:00 PM
Gum Guggul–New Benefits for Heart Health from an Age-Old Herbby Richard Conant, L.Ac., C.N.The 1990's have seen a growing interest in herbs from India's ancient Ayurvedic tradition. One Ayurvedic herb in particular, "gum guggul," stands at the forefront, thanks to its rather remarkable benefits for the heart and cardiovascular health. A relative of myrrh and Frankincense, gum guggul is a resin tapped from India's Commiphora mukul tree. Known more commonly in the Far East as simply "guggul," the herb has proven to be one of the most effective natural cholesterol-lowering agents ever discovered. Cholesterol reductions with guggul can be twenty percent or higher, and the herb also raises HDL, the more beneficial form of cholesterol. Studies also show guggul may help prevent atherosclerosis, by retarding the formation of fatty, cholesterol-laden deposits in blood vessel tissues. Recent research on guggul has revealed that guggul also blocks the oxidation of LDL cholesterol, by acting as an antioxidant. LDL, which carries cholesterol from the liver to the rest of the body, is generally regarded as a key element in the development of atherosclerosis. But only when it is oxidized by free radicals does LDL accumulate in arteries. It its unoxidized or "native" state, LDL is more or less benign. Checking LDL oxidation is vital to keeping blood vessels free of plaque.1 (This is one of the major reasons why antioxidants are so important.) Guggul, by both lowering blood cholesterol and acting against LDL oxidation, now stands out as one of the world's most valuable herbs for heart health. Guggul first caught the attention of the scientific world in1966, thanks to an Indian medical researcher who submitted a doctoral thesis on gum guggul.2 Her interest had been kindled by references to the herb in a centuries-old Ayurvedic text. Apparently, poor cardiovascular health and atherosclerosis were a problem back then just as they are today. Translated from Sanskrit, this text describes, in elegant detail, a condition called "coating and obstruction of channels." The cause, according to the ancient writers? Faulty metabolism due to overeating of fatty foods and lack of exercise. Death was said to be the end result of leaving this condition uncorrected. The recommended treatment plan emphasized diet and herbs, chiefly gum guggul.3 References to guggul in ancient literature actually go back even farther. The herb is mentioned in the Vedas, the holy scriptures of India believed to be anywhere from 3,000 to 10,000 years old. One stanza is translated as follows: "Disease (consumption) does not afflict and the curse never affects whom the delicious odor of the healing Guggul penetrates (spreads). The diseases also flee away in all directions from him like horses and deer, O Gugulu! Either born from Sindhu or from the sea. I chant your name for the removal of diseases."3 Struck by the obvious similarity between "coating and obstruction of channels" and atherosclerosis, the Indian researcher decided to study gum guggul's effect on blood fats in rabbits. Over a two-year period, the animals were fed hydrogenated vegetable oil to artificially raise their cholesterol levels. Guggul was administered to one group of rabbits, while the rest served as controls. At the end of the study the rabbits given guggul had normal cholesterol and blood lipid levels. Their arteries showed no fatty streaks or plague deposits. This caught the attention of the Indian scientific community, and numerous clinical trials ensued, both on animals and humans. In study after study, guggul consistently produced substantial reductions in cholesterol and triglyceride levels, while raising HDL. The active ingredients in guggul are a group of natural plant sterols. Among these, substances called "guggulsterones" are the most important ingredients for the cholesterol and blood fat lowering properties of guggul, with the other sterols acting as a synergistic supporting cast.4 A number of mechanisms are suggested, although not definitely proven, for how the herb works; these include reducing the synthesis of cholesterol in the liver, enhancing cholesterol removal from the gut, stimulating thyroid function and increasing the number of receptors in the liver for uptake of LDL.3,5 Guggul extracts are now standardized for guggulsterone content. The herb naturally contains about 2 percent guggulsterones. Quality extracts contain a minimum of 2.5 percent, which assures the user is getting a product potent enough to produce results. Since the late 1980's clinical trials have used the standardized extract.6,7,8 The product is readily available in the U.S. The ability of guggulsterones to prevent oxidation of LDL was discovered in a 1997 study done by scientists at the Central Drug Research Institute in Lucknow, India.9 This study sheds light on how guggul works against "coating and obstruction of channels." Remember that oxidized LDL forms the plaque that coats and eventually obstructs blood vessels. The researchers mixed LDL from human blood with a free radical promoting agent, either alone or in combination with guggulsterones. Samples were then analyzed for the presence LDL oxidation byproducts. The results showed that guggulsterones strongly protect LDL from being oxidized. Guggulsterones block the formation of hydroxyl radicals, a potent type of free-radical that attacks cell membranes. Guggulsterones may also help keep the heart muscle itself healthy. When the heart muscle is deprived of oxygen, a condition known as "myocardial ischemia," it can be severely damaged by free radicals. The body tries to counter this with SOD, a key enzyme present in cells that neutralizes free radicals. SOD levels are significantly reduced in damaged heart tissues. Guggulsterones have been found to reverse this decrease by more than two-fold.10 Like the writer of that age-old verse found in the Vedas, contemporary herbalists hold gum guggul in the highest regard. Backed as it is by scientific research linked to centuries of traditional use, gum guggul has a bright future as a natural resource for maintaining normal cholesterol and blood fats, and for protecting heart health. References 1. Heinecke, J.W. Free radical modification of low density lipoprotein: mechanisms and biological consequences. Free Radical Biology & Medicine 1987;3:65-73. 2. Satyavati, G.V. Effect of an indigenous drug on disorders of lipid metabolism with special reference to atherosclerosis and obesity (Medoroga) M.D. thesis (Doctor of Ayurvedic Medicine). Banaras Hindu University, varanasi, 1966. 3. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82. 4. Dev, S. A modern look at an age-old Ayurvedic drug-guggulu. Science Age July 1987:13-18. 5. Singh, V. et. al. Stimulation of low density lipoprotein receptor activity in liver membrane of guggulsterone treated rats. Pharmacological Research 1990;22(1):37-44. 6. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28. 7. Agarwal, R.C. et. al. Clinical trial of gugulipid-a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34. 8. 'Gugulipid' Drugs of the Future 1988;13(7):618-619. 9. Singh, K., Chandler, R. Kapoor, N.K. Guggulsterone, a potent hypolipidaemic, prevents oxidation of low density lipoprotein. Phytotherapy Research 1997;11:291-94. 10. Kaul, S. Kapoor, N.K. Reversal of chnages of lipid peroxide, xanthine oxidase and superoxide dismutase by cardio-protective drugs in isoproterenol induced myocardial necrosis in rats. Indian Journal of Experimental Biology 1989;27:625-627.
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Date:
May 09, 2005 06:10 PM
It's in the BloodNatural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul BubnyThe National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen. “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks. “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).” At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke. While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!” Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.” And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.” Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.” King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.” Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.
"Blur of Products"With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.” To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following: Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent. Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels. Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.” “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.” On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone. Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients. Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs. Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic. Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action. Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.” Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take. “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels. Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids. Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period. “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake. For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.” Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients. Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO. Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols. Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol. Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky. “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.” Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.” Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said. However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.” Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.” Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols. Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”
New WeaponsThere are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise. With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.” Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM. “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/
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