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Search Term: " Samples "
The Unsettling Truth About Plastic: Microplastics Found in Human Stool Samples   
Date:
July 29, 2023 11:04 AM
We all know that plastic pollution is a serious issue, but what we may not be aware of is that we are consuming it. Yes, you read that right. The researchers have recently discovered microplastic particles present in human stool Samples, making us ingest the plastic we produced. It is not only our oceans and landfills that are clogged with plastic waste, but even our bodies, and that's alarming.
According to the study, participants from Finland, Italy, Japan, the Netherlands, Poland, Russia, the United Kingdom, and Austria were tested for ten different types of plastics, and nine types were found in their stool Samples. On average, participants had 20 microplastic particles per 10 grams of stool. That's a concerning number.
As we all know, plastic is everywhere, from plastic bags to water bottles, from household items to toys, and the list goes on. A recent study revealed a frightening fact that our food, especially seafood and sea salt, and tap water and bottled water contain microplastics too. It is surprising to know that plastic is all around us, and we are consuming it daily.
Apart from being present in our bodies, research suggests that microplastics may have adverse effects on our gut microbiota. As per a study conducted by the University of Vienna, polystyrene microplastics adversely affected the gut barrier, microbiota, and metabolism of mice. Moreover, it can lead to a bacterial imbalance in our gut, decreasing our immune response.
Microplastics have a size smaller than 5 millimeters and are much smaller than the size we can see with naked eyes. Therefore, our bodies cannot filter them out. As a result, these microplastics can cause inflammation, obstruct our digestive system, and damage our gut lining.
The impact of plastic on the environment and marine life is alarming, but knowing that we, humans, are part of the problem is overwhelming. The amount of plastic waste we produce every year is immense, and if we don't change our ways, it will only get worse.
The Solution to Microplastics in Our Digestive Tract Could Be Psyllium Husk and Inulin.
Psyllium husk is a soluble fiber that is derived from the seeds of the Plantago ovata plant. It is a powerful colon cleanser that can rid our bodies of toxins, including microplastics. When mixed with water, psyllium husk forms a gel-like substance that bulks up and moves through our digestive tract, trapping and removing microplastics along the way. Psyllium husk is also known to help regulate bowel movements and reduce inflammation in our gut.
Another solution to microplastics in our digestive tract is prebiotics, specifically inulin. Inulin is a type of soluble fiber that feeds friendly bacteria in our gut, promoting gut health. Studies have shown that inulin can strengthen the gut lining, which can reduce the absorption of toxins like microplastics into our bodies. Inulin can also help regulate bowel movements and reduce inflammation in our gut.
In addition to psyllium husk and inulin, there are other steps we can take to reduce our exposure to microplastics. One such step is to avoid plastic packaging and utensils when possible and opt for reusable and sustainable options instead. We can also be mindful of the products we use that contain microplastics, such as cosmetics and cleaning products, and choose more natural alternatives.
It is also important to note that the effects of microplastics on our health are still being studied, and more research is needed to fully understand the extent of their impact. However, taking steps to reduce our exposure to microplastics and improve our gut health can only be beneficial for our overall well-being.
The discovery of microplastics in human stool Samples is the harsh reality of the plastic pollution crisis. The studies strongly suggest that it may have severe implications for human health (we haven't even touched on the topic of endocrine disruptors due to plastics), and we must take action to reduce plastic consumption and pollution.
Reducing plastic waste from our daily lives might seem challenging, but it's essential if we want to create a healthier planet for ourselves and the generations to follow. Being more conscious of our daily habits in using plastic, choosing eco-friendly alternatives, and encouraging others to do the same can go a long way in reducing our plastic footprint.
We must work together as a community to reduce plastic waste and promote a sustainable future. The change starts with us, and together we can make a difference. You can get started to better health by adding psyllium husk and inulin to your daily supplement regiment. Your colon will thank you for it!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6581) Treat psoriasis naturally with vitamin D and zinc 
Date:
March 28, 2019 05:13 PM
Over 7.5 million Americans suffer from Psoriasis, and researchers in Iraq have taken it upon themselves to spot any potential nutrient deficiencies associated with the condition. Physicians took blood samples from Iranian participants, and they surprisingly found that those who had a psoriasis diagnosis were shown to have insufficient levels of vitamin D. These levels were so insufficient, that they were actually 60% less than that of an individual with healthy levels of vitamin B. Key Takeaways:
"The team found that vitamin D levels in those with psoriasis were at least 60 percent lower than healthy individuals. Similarly, zinc levels of people with psoriasis were lower by a third, compared to those who do not have the condition." Read more: https://www.naturalnews.com/2019-01-27-treat-psoriasis-naturally-with-vitamin-d-and-zinc.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6101) New study links negative mood with higher levels of inflammation
Date:
January 05, 2019 02:26 PM
New research from Penn State University has shown that being in a negative mood can be linked with higher levels of inflammation and may be a signal of poor health. Inflammation is a contributing factor to many diseases such as diabetes and cancer. These negative emotions include sadness, anger, and depression. 220 participants reported on their moods and blood samples were taken to measure the inflammation present in the body. This was the first study to research how the two are linked. The long-term goal of the researchers is that the information will eventually lead to insights into how interventions can improve mood and ability to cope with stress. That will in turn help break the cycle of disease associated with inflammation. Key Takeaways:
"New US research has found that a negative mood, such as feeling sad or angry, may be linked with higher levels of inflammation and may be a sign of poor health." Read more: https://www.malaymail.com/s/1705392/new-study-links-negative-mood-with-higher-levels-of-inflammation
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5935) Eating too much processed sugar increases your risk of Alzheimer's
Date:
September 26, 2018 09:52 AM
According to recent research, people that consume a lot of processed sugars run a greater risk of developing Alzheimer's disease. What happens is the high sugar levels damage a major enzyme called macrophage migration inhibitory factor. Previous research has already shown that people with diabetes are more likely to develop this disease. However, the most recent research looked at brain samples of people with and without this disease and the process of glycation. It showed that glycation damages the essential enzyme which regulates insulin and the immune response. Key Takeaways:
"Research has found that a high intake of processed sugar can raise the risk of Alzheimer’s disease." Read more: https://www.naturalnews.com/2018-09-12-eating-too-much-processed-sugar-increases-your-risk-of-alzheimers.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5773) Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries
Date:
June 08, 2018 09:16 AM
Parasites are a more common problem in some parts of the world, where soil quality is particularly conducive to their survival and growth. Unfortunately, for individuals that get infected with these parasites, it's becoming harder to get rid of them, as successive strains become more resistant to drugs. Fortunately, new research is discovering that keeping parasites at bay and destroying those already present may have more to do with the environment of the gut. Individuals from villages in Indonesia and Liberia were the data pool used to find guts harboring parasites as well as those free of them. It was found that some bacteria were actually assistive of the parasites, while others made it hard on them. Since inflammation is the way that the gut generally fights off parasitic invasion, those bacteria that are anti-inflammatory are not useful in ridding the body, although those that aid in producing an inhospitable environment are. It may be that a eating a great deal more fermented foods could be a key, as such foods encourage the production of friendly and useful bacteria. Key Takeaways:
"Your ability to fight off parasitic worms may be aided by your gut microbiota." Read more: https://www.naturalnews.com/2018-06-05-gut-microbes-can-fight-parasites-probiotics-may-reduce-infections-and-severity-of-infections-in-developing-countries.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5630) Men can boost brain health and enhance performance with ginkgo
Date:
October 08, 2017 10:14 AM
Men can greatly boost their brain health and enhance their performance with ginkgo. Young and active men can greatly benefit from taking extracts from Ginkgo biloba leaves. This is according to a recent study. The great thing about Ginkgo is that it can also combat memory issues that are related to dementia. They help boost the brain functioning in people that are having issues with dementia. Rats were used in studies and some interesting things were discovered. Key Takeaways:
"According to the researchers, the plant extracts’ positive effects may be stemming from its polyphenolic compounds." Read more: https://www.naturalnews.com/2017-10-02-men-can-boost-brain-health-and-enhance-performance-with-ginkgo.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5319) Proportions of gut bacteria play a role in weight loss: Study
Date:
September 18, 2017 12:14 PM
The proportions of gut bacteria that you have play a role in your weight loss. Losing weight is something that many people want to achieve in life. Once we get rid of bad eating habits and we eat healthy and exercise as well, then we are on a good path and will lose a lot of weight. There is new research out that shows how our gut microbiota play a big role in our weight loss and nutrition. Key Takeaways:
"New research suggests that gut microbiota play an important role in your nutrition and the development of obesity." Read more: http://www.belmarrahealth.com/proportions-gut-bacteria-play-role-weight-loss-study/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5260) Fake weed: Why does government marijuana look so weird?
Date:
March 27, 2017 08:59 AM
The government, yet again, is trying to control/discourage research and development of products related to marijuana. Outlined here is how the only products available for research studies are outdated, ineffective, and poor quality marijuana plants. Most plants that are used are grown in outdated environments and conditions. In states where the plant is legal, it can't be used for research purposes. The product must be the sub-standard, government issued plants. People who could benefit from this research, should pay attention to, and follow-up on this report. Key Takeaways:
"Photographs of the government marijuana samples received by Sisley show a substance that bears almost no resemblance to commercial marijuana." Read more: http://www.naturalnews.com/2017-03-23-fake-weed-why-does-government-marijuana-look-so-weird.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4302) Toxins in Your Fast-Food Packaging?
Date:
February 06, 2017 07:59 AM
Fast food isn’t exactly known for its health benefits, but a new U.S. study suggests even the packaging may be harmful. That’s because the study found one-third of fast food packaging contains chemicals that give it stain-resistant, water-repellant and nonstick properties. The trouble is these fluorinated chemicals have also been linked to an increased risk of certain cancers, hormone problems, high cholesterol, obesity and immune suppression in human and animal studies. Key Takeaways:
"Major U.S. manufacturers voluntarily phased out PFOA and PFOS for most uses starting in 2011, but other countries still produce them." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3893) Moderate exercise can boost fertility in men
Date:
December 18, 2016 10:59 AM
For all the men out there that don't think its possible to increase their sperm count and fertility, this study will prove you wrong. According to recent research, moderate exercise can very much help out in the struggle to maintain fertility even for men who might be increasing a bit in age. Key Takeaways:
"Sperm Samples were evaluated before, during and after the exercise period, and were compared with the results from the control group, who did not exercise. While all exercising men showed improvements in their semen quality – probably because of weight loss – moderate but continuous training, which included running on a treadmill for 25 to 30 minutes three to four days per week, showed the best results regarding semen quality." Reference: //www.naturalnews.com/2016-12-12-moderate-exercise-can-boosts-fertility-in-men.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3666) "Fake" olive oil warnings don't tell the real story: In truth, popular olive oil products are "real" oils which are oxidized, rancid or cut with cheaper oils
Date:
December 13, 2016 02:59 PM
Like cooking with olive oil? You won't believe the real story behind these 8 popular brands! A food scientist explains new data from UC Davis that shows the heavy processing olive oil goes through between tree and table. Learn the secrets behind one of America's most popular cooking oils. And find out where you can get real, delicious olive oil, thanks to Natural News! Key Takeaways:
"As a forensic food scientist and lab science director, I wanted to get to the bottom of this “fake olive oil” news, so I went right to the source:The “Evaluation of Extra-Virgin Olive Oil Sold in California” report from the UC Davis Olive Center." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3636) America is about to realize just how poisoned conventional food really is ... Lab testing for glyphosate about to go 'viral'
Date:
November 24, 2016 08:59 AM
Do you ever really stop to think about what goes in your food and what you're putting in your body? Chances are that you probably don't, although there's a small minority of Americans that seems to. "America is about to realize just how poisoned conventional food really is ... Lab testing for glyphosate about to go 'viral'" talks about what's wrong with the food the average American eats, and how science has found a means to prove this. Key Takeaways:
"There is no safe level that can be consumed, even though it's regularly found in American food and water." Reference: //www.naturalnews.com/055968_weed_killer_Roundup_glyphosate_testing.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3499) Are These Factors Causing Inflammation In Your Body?
Date:
November 08, 2016 03:04 PM
Inflammation is caused by a number of factors. For instance, the hormonal changes experienced by women during menopause can cause chronic inflammation. The production of the hormone cortisol during stressful moments can also contribute to inflammation. Some foods are another possible contributor. For instance, polyunsaturated oils like peanut, soybean and corn lead to inflammation. Consuming a diet balanced in omega-3 and omega-6 fats can help balance this out. Inflammation can have negative long-term consequences on the body, so it’s best to consult a doctor and make healthy lifestyle choices. Key Takeaways:
"Along with other factors, there are certain foods that you consume which might end up causing inflammation. These are regular food items that we have without even realising that they are the cause of inflammation." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3408) new from Now Foods, Empty Glass Bottles to Mix Your Own Oils
Date:
September 28, 2016 05:07 PM
Empty Glass Amber Glass bottles For The DIY beauty Products With more and more consumers seeking healthier, natural alternatives to chemically laden mass market home products, the do-it-yourself (DIY) market continues to gain in popularity. Making DIY beauty products is a trend that continues to gain steam, especially for those using essential oils and carrier oils such as jojoba, shea, and grape seed.
Now Solutions health and beauty line is well-positioned to capitalize on this emerging consumer trend, and we're making it even easier for you to do it your self. These Empty bottles include blank labels so you will have everything you need to create your own recipes and Samples based on individual tastes. Enjoy!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3318) Adrenal Glandular Supplements
Date:
May 18, 2014 11:06 AM
Healthful supplements can help keep up the strength of your organs by guaranteeing legitimate working of the glandular framework. Like all organs, the organs need healthful backing. Particularly when anxiety exhausts the assemblage of put away supplements. Your organs produce and discharge substances into the body for the body’s utilization. A breakdown or an irregularity of any one glandular substance can make gigantic issues around the body. Organs has two classifications. The exocrine organs - open onto a surface of an organ; or other structure, through a pipe. Samples of the exocrine organs incorporate the salivary of the mouth and the sweat and oil organs of the skin. Other exocrine organs are found in the kidneys, the mammary organs and the digestive tract. The endocrine organs - are ductless, in this way emitting the substances they prepare (hormones) straightforwardly into the circulation system. By emitting hormones the endocrine organs help manage almost all substantial capacities. Samples of the endocrine organs incorporate the adrenal (on the kidney), the pancreas (behind the stomach), the pituitary organ (at the base of the mind), the pineal organ (connected to cerebrum), sex organs (testes/ovaries), the thymus organ (underneath the thyroid) and the thyroid and parathyroid organs (in the neck). Supplement source
Maintain a strategic distance from perk and soft drinks, which can dispose of vitality in your body and make you feel more tired. Furthermore, you ought to change your lifestyle. For instance, take a stab at dozing in until nine in the morning if at all conceivable and verify you practice and do exercises that minimize stress. Consume customarily and does something fun while staying far from contrary individuals and movements. Caution in taking the supplement In addition, you may want to take the fatigue supplements each day to help you recover from this glandular dysfunction and make you feel more energetic. If you have this syndrome, then there are supplements that you can take to help address the problem. Before taking any enhancers, contact your doctor and have him or her run a test first to see if you suffer from adrenal fatigue syndrome.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3121) History And Uses Of Xylitol
Date:
February 07, 2012 07:50 AM
Xylitol is the 5-carbon sugar which is found within the birch tree sap and it's naturally found in the fibers of various vegetables and fruits. This is a sugar-alcohol sweetener commonly used as the sugar substitute. History of xylitol Although discovered in the 19th century during the Second World War, Xylitol has been recognized ever since the tardy 1800s. The researchers from Germany and France were the first individuals to try to produce this product approximately 100 years ago, but ended up creating syrup-like consistency mixture. This product became commercially available in the 1960s and the commercial process is still the same as it was during the 1960s. Before 1943, the scientists' categorized this sugar with various sugary carbohydrates (polyols) and it lingered so till the beginning of the war-associated deficiency of sugar which initiated the call for an alternate sugar. This initiated further research in to the xylitols insulin-independent properties, this resulted in discovery of its other biological benefits. In 1962 this chemical was introduced in the infusion therapy demonstrating that it can be introduced to ill individuals. The commercial production process involves extraction of Polysaccharides rich in Xylose from various agricultural by-products and hardwoods. These are hydrolyzed with various intense acidic treatments and then it is purified before hydrogenation is done. This process needs a lot of harsh chemicals and is quite expensive and inefficient. It was until 1970 that the odontological benefit of xylitol was ascertained in Finland, Turku. The initial study of the effects of this sugar on the dental plaque began during the same year. This resulted in large scale production of xylitol, in 1974 by the Finnish sugar company. Sugar-free dental product was first launched in Finland which was a xylitol chewing-gum. How xylitol works This sugar can prevent cavity in various ways by actually blocking the tooth decaying process. The bacteria causing decay cannot ferment this sugar into acids as it does with other sugars including dextrose, fructose, glucose and sucrose. This results in production of less acidic by-product thus interfering with the dental plaque environment which favors decaying. This results in prevention of tooth demineralization. The high pH condition caused by xylitol sugar is not favorable for the cariogenic bacteria which are responsible for decaying. This results in fewer bacteria in the plaques and long-term exposure has an effect on which type of bacteria will prevail within the plaque. This also inhibits the growth of specific xylitol-sensitive bacteria strain. Since they cannot breakdown this sugar, they end up not reproducing and growing in population. The lack of fermentable sugars results in creation of anti-cavity effect. The starvation effect created by this sugar prevents accumulation of cariogenic bacteria in the plaques. Long term xylitol exposure results in change of predominant cariogenic bacteria to xylitol-resistant strains from xylitol-sensitive. This xylitol-sensitive strain of bacteria cannot colonize the plaque since they have less adhering capabilities. The less acidic condition in the dental plaque interface created by this sugar can initiate demineralization. Demineralization occurs when the plaque interface is at a pH of 5.5 or below since fewer bacteria live in the plaques. Studies have showed that demineralized tooth Samples immersed in a solution containing 20% xylitol experienced a great remineralization degree. This is noted in the deep and middle tooth layers.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2558) Copper Vitamins
Date:
February 13, 2009 10:47 AM
Copper is an essential trace mineral that can impair the ability of white blood cells to fight infection with even the slightest deficiency. Copper is necessary for the proper absorption of iron in the body. It is found primarily in foods that contain iron. If the body does not get a sufficient amount of copper, hemoglobin production decreases, causing copper-deficiency anemia to potentially result. There are a variety of enzyme reactions that require copper. Copper is essential as a cross-linking agent for elastin and collagen. It is also a catalyst for protein reactions and is also needed for oxygen transport. Copper is used for the metabolism of essential fatty acids. Copper deficiency can result in a variety of symptoms. Among these symptoms are diarrhea, inefficient utilization of iron and protein, and stunted growth. The development of nerve, bone, and lung tissue can be impaired in babies and the structure of these body parts may also be altered. Because the body is unable to manufacture copper, it must be obtained through the diet. Too much copper trace mineral produces a condition known as copper toxicity or copper overload. In order for the body to work properly, it is essential that it has a proper balance of copper and zinc. An imbalance can lead to thyroid problems. Additionally, low copper levels can contribute to mental and emotional problems. For example, copper deficiency may be a factor in anorexia nervosa. Although the FDA has never published a Recommended Daily Allowance for copper, the National Research Council recommends that adults get from 1.5 to 3.0 mg per day, while children obtain 1.5 to 2.5 milligrams and infants less than six months old obtain 0.4 to 0.6 milligrams. For most people, a normal healthy diet will provide the correct amount of copper. Copper deficiency is most likely to occur in babies who are fed only cow's milk, persons suffering from a malabsoprtion syndrome known as sprue, persons suffering from kidney disease, and those who chronically take mega-doses of zinc. Long-term use of oral contraceptives can upset the balance of copper in the body. This can cause either excessively high or excessively low copper levels. Copper levels can be determined through a blood test, urine Samples, and hair analysis. The basis for a nutritional program to balance body chemistry is determining mineral levels and ratios. The following nutrients are helpful in combating copper deficiency. The dosages recommended are for adults unless otherwise specified. For a child between the ages of twelve and seventeen, the dosage should be reduced to three-quarters the recommended amount, while one-half the recommended amount should be used for a child between six and twelve. A child under the age of six should use one-quarter the recommended amount. Copper should be taken in dosages of 5 mg daily for a month, and then reduced to 3 mg daily. This helps to restore copper in the body. It is recommended that a copper amino acid chelate is used. 30 mg of zinc should be taken daily, as it is needed to balance with copper. This amount should not be exceeded and a zinc chelate form should be used. Iron should be taken as directed by a physician, as copper deficiency may cause anemia. Be sure to use a chelate form and do not take iron unless anemia is diagnosed. Additionally, a multivitamin and mineral complex should be taken as directed on the label since all nutrients are necessary in balance. In conclusion, copper is a wonderful mineral that can help one with immunity and much more. Remember that copper should only be taken in low dosages of 1 to 3 milligrams per day. Copper can be found at your local or internet health food store. *Statements contained herein have not been evaluated by the Food and Drug Administration. Copper is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1965) Pinolenic Acid - Appetite Control
Date:
April 25, 2008 02:50 PM
Mention "pine nuts" and peoples’ mouths are apt to start watering for a taste of garlicky pesto or fragrant pilaf. Ironically, the same ingredient that is so irresistible in gourmet cooking may help curb our out-of-control appetites. But only a particular variety of pine nut—Pinus koraiensis from Korea—will do. Source Naturals PineSlim is a Korean pine nut oil (PinnoThin™). A small-scale study suggests that PineSlim may reduce feelings of hunger by increasing concentrations of appetite-suppressing hormones. The study also suggests that a feeling of fullness is experienced 30-60 minutes after taking PineSlim. For best results, PineSlim should be taken while following the Maximum Metabolism Weight Loss Plan™ enclosed in every bottle. Enjoying good food is part of a healthy lifestyle, but too often we don’t know when to stop. PineSlim can help by addressing one of the most basic of the dozen deep metabolic systems identified by Source Naturals as critical to your optimal health: Hormones/Metabolism. Less Calories for Improved Health According to a National Health and Nutrition Examination Survey, an estimated 66% of U.S. adults are overweight. A normal body fat level is one of the factors associated with many markers of good health, including insulin efficiency, healthy inflammation response, good circulation, and normal cell regeneration. One of the best ways to achieve healthy weight is by curbing the amount of calories we take in—but that’s not always easy to do. Now an ancient Asian food source may help. Korean Pine Nuts—Traditional Asian Food The Korean pine nut (Pinus koraiensis) has been used as a food source for centuries and is often served as a snack at social events in China. Korean pine nuts grow on evergreen trees that produce seeds (commonly referred to as nuts) that are rich in oil, particularly oleic, linoleic, and pinolenic acids. Pinolenic acid is a fatty acid, which may influence healthy blood pressure. According to recent research, pinolenic acid also may increase concentrations of the satiety hormones glucogon-like peptide-1 (GLP- 1) and cholecystokinin (CCK). Appetite-Suppressing Hormones Both GLP-1 and CCK are hormones that have been found to increase satiety and suppress appetite in normal-weight humans. They are believed to work by delaying gastric emptying. Retaining food in the stomach for a longer period of time may prolong a feeling of fullness. In a randomized, double-blind trial, 18 overweight women received 3.00 grams of Korean pine nut oil (PinnoThin™)—the same amount as one daily dose of Pine Slim—or an olive oil placebo before a carbohydrate meal. Hormone measures of CCK and GLP-1 were taken from blood Samples, and subjective measures of appetite were recorded. The study demonstrated a significant increase in appetite-suppressing CCK and GLP-1 hormones at 30-60 minutes after supplementation. Your Source for Advanced Nutrition The plant world offers an abundance of health promoting compounds. Today exciting discoveries are emerging from research into the health benefits of botanicals. The development of PineSlim reflects Source Naturals’ commitment to manufacturing supplements on the cutting edge of nutritional science. We are glad to partner with your local health food store in bringing you nutritional resources that help you take charge of your health. References: Causey JL (3/28/06) Korean Pine Nut Fatty Acids Induce Satiety-producing Hormone Release in Overweight Human Volunteers, American Chemical Society Abstract, “Health Benefits of Lipids” Symposium. ABSTRACT 0117: TECH-3. Fontana L. (2006) Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 295(13): 1577-1578. Masoro EJ. (2005) Overview of caloric restriction and ageing. Mech Ageing Dev. 126: 913-922. Sugano M, Ikeda I, Wakamatse K, Oka T. (1994) Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. British Journal of Nutrition. 72:775-783.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1773) Don’t Live With Pain, Live Pain Free – Curamin Is The Answer
Date:
April 24, 2008 04:32 PM
Fact, more than 50 million Americans suffer from chronic pain. Chronic, meaning pain that continues daily, weekly, monthly, and yearly, pain may which never end with out help. According to the Journal of the American Medical Association, pain is the primary reason people seek the advice of a doctor or health practitioner, and the number one reason people take alternative medicine. A new revolutionary dietary supplement for pain and inflammation is now available on the market. Introduced by Terry Lemerond, this new formula called Curamin has changed thousands of lives. This formula contains three anti-inflammatory herbs and one amino acid that can help one live a more normal pain free life. The first ingredient: Curcumin is a substance found in turmeric. Curcumin contains curcuminoids which have been shown to reduce inflammation and pain. Turmeric is an ayurvedic herb discovered in India and brought over to the United States has demonstrated amazing results. Turmeric has been cooked with and used as a medicine for over 2000 years. The active ingredient in turmeric is curcumin which has demonstrated six important properties. Curcumin has anti-inflammatory, antioxidant, antiviral, antibacterial, antifungal, and anti-cancer properties. As you can see this herb has made quite a name for its self. The second ingredient is Boswellia. Boswellia contains boswellic acid which is the active ingredient in this herb as well. This herb has also demonstrated its natural ability to fight inflammation and more. Research suggests that Boswellia’s active ingredient can actually modulate the expression of the genes involved in the body’s inflammation response thus giving itself an anti-inflammatory name. The third ingredient is DLPA an amino acid also known as DL Phenylalanine. This amino acid can help the body product more serotonin in the brain. D-phenylalanine can actually help reduce chronic pain through the production of serotonin. Serotonin helps one feel more relaxed and level headed this is something everybody needs when it comes to pain that drives them crazy all day long. Those people consuming MAO inhibitors and anti-depressants need to avoid DLPA with out a doctor’s supervision. The forth and last ingredient in Curamin is nattokinase. Nattokinase is an extract from fermented soy cheese. For thousands of years natto has been consumed by the Japanese people with out even know the health benefits of its consumption. Nattokinase can help the body fight blood clots, thin the blood, and fight pain and swelling. This new formula Curamin has the three top herbs that fight inflammation in the body, when combined with DLPA, this product has the amazing ability to fight pain by attacking the source of pain, inflammation. Recommended doses for curamin are 2 capsules in the morning and 2 more capsules in the evening after work. Some may need a stronger dose at first, this is where one should take 4 capsules at one time in the morning for the first few days then step back to 2 in the morning and 2 in the evening. We have free Samples available upon request and back the curamin product with a 100% satisfaction guaranteed. So if you are un-satisfied, just return the unused portion of the product for a full refund of the purchase price minus shipping costs. So what are you waiting for? Are you ready to live pain free? Give curamin a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1770) The Prevention and Treatment or Prostate Cancer
Date:
April 10, 2008 01:36 PM
Last week I shared with you the controversy surrounding the use of PSA screening to determine the status of the prostate. There are many doctors who do not believe that using PSA is accurate enough to rely on for determining whether or not a high PSA indicates prostate cancer. Many men, who have a high PSA, after more detailed examination, did not have cancer and men with a low PSA did have cancer. Some physicians do not believe that the current methods of diagnosing prostate disorders are saving lives. Also, there is a group of physicians nationwide that strongly believe the best treatment is no treatment but rather a “watch and wait” approach. Prostate cancer usually is slow growing and more than 70% of men who develop it are over 65. The older a man is, the more likely he is to die of some other condition before his prostate cancer becomes a real threat. To reiterate, the American Cancer Society states, “at this time watchful waiting is a reasonable option for some men with slow growing cancers because it is not known whether active treatment such as surgery, radiation therapy or hormone therapy prolongs survival”. So what action can be taken? While prostate enlargement (BPH) is not related to prostate cancer, it can elevate PSA scores and can cause symptoms in 50% of men by age 80 and nearly all will show signs of BPH by age 85. If you have early symptoms of BPH such as frequency of urination, a burning feeling after urination and the caliber of stream that isn’t what it used to be, getting up several times through the night and low back pain, taking a good prostate support formula will be your best treatment and prevention. Most men will notice a remarkable improvement within a few weeks. A good prostate support formula will provide relief for 80-90% of all men from these annoying symptoms. But what about prostate cancer? The best cure for prostate cancer is prevention. I’ll give you a complete supplement program for prevention but first what about PSA testing? “I don’t believe in screening for something when it’s too late. By the time cancer develops a positive mammography or a true high PSA are likely too late, or if fortunate, that particular cancer will not be a problem. It makes far more sense to prevent the problem in the first place. And there is clear data, prevention is possible”. Dr. Robert J. Rowen, MD, Second Opinion, Soundview Communications. My recommendation, based on research of several scientific studies, includes various nutritional supplements and herbal extracts. Following are several very important studies that all men should be aware of. In 1966 Dr. Larry Clark of the University of Arizona published startling data suggesting that prostate cancer could be reduced by as much as an amazing 60% by supplemental yeast derived selenium, 200 mcg per day. Selenium is a powerful antioxidant and participates in key and crucial detoxification and free radical scavenging enzymes (80-90% of all disease is caused by free radical damage and inflammation). Selenium is one of a number of antioxidants to prevent this free radical damage; In 1999 a New Zealand study published in the British Journal of Cancer documented a 40% lower incident of prostate cancer in men with the highest levels of omega-3 fatty acids EPA and DHA in their blood. These findings have been confirmed in other omega-3 fatty acid studies. Conversely, another published report documents a high level of omega-6 to omega-3 fatty acids in invasive prostate tissue Samples. Taken together with recent reports on high levels of omega-6 fatty acids (soy, sunflower, safflower, peanut, corn and most vegetable oils) linked to breast cancer, a common thread emerges. The American diet is overwhelmed with omega-6 oils. Excessive use of omega-6 fatty acids are cancer causing and also cause inflammation. Trans fatty acids from hydrogenated oils seriously add to the problem. There are other nutrients that have shown to reduce prostate-cancer risk. Vitamin E and lycopene have also shown to prevent prostate cancer. Lycopene is commonly found in tomatoes, especially cooked tomatoes. If you like spaghetti sauce or salsa, this is a great way to fight prostate cancer. While vitamin E, selenium, lycopene and omega-3 fatty acids are all great prostate supporting nutrients, through research I found a much more powerful combination of food grade molecules that can prevent and treat cancer. Extensive research in the last few years has revealed that regular consumption of certain fruits and vegetables can reduce the risk of prostate cancer. Fruits and vegetables having the highest degree of prostate cancer protection are the following: grapes (resveratrol), garlic, tomatoes, hot peppers, turmeric (curcumin), ginger, berries, milk thistle, cloves and fennel. These foods are protective because they are extremely active and excellent antioxidants. My favorite is turmeric (curcumin) because not only is it an antioxidant, it is also an anti-inflammatory agent. When it has this dual effect it is many times more potent than other types of food. In the United States there is 30 times more prostate cancers diagnosed than there are in India where turmeric is consumed liberally in most of the Indian dishes. Cancer does not begin shortly before it’s diagnosed. The origin of cancer may be years or decades in the process before it is even diagnosed as such. It is a multi-step process that goes through various phases such as cellular damage and transformation and culminates in the acquisition of invasive potential angiogenic properties and establishment of metastatic lesions. This process, and probably rightly so for all cancers, can be activated by any one of the various environmental carcinogens (cancer causing); all forms of tobacco products, industrial emissions, gasoline vapors, inflammatory agents, food coloring and preservatives, excessive UV rays, alcohol, hair dyes, cleaning products and drugs. The multi-step process of these cancer causing compounds progress in three stages; tumor initiation, promotion and progression phases. A powerful antioxidant/anti-inflammatory can prevent most if not all of the damaging effects when taken on a daily basis. Several population based studies indicate that people in Southeast Asian countries have a much lower risk of acquiring colon, gastrointestinal, prostate, breast and other cancers when compared to their western counterparts. It is very likely that constituents of their diet such as garlic, ginger, turmeric, onion, tomatoes, cruciferous vegetables, chili’s and green tea play an important role in their ability to avoid these cancers. These foods, or key active extracts from these foods, are known to block the NF-kB activation process. Also, several phytochemicals such as curcumin, resveratrol and green tea catechins have been shown to suppress AP-1. Several chemopreventative phytochemicals including curcumin, resveratrol and green tea have been recently shown to be powerful inhibitors of several growth factor receptors including EGFR. Curcumin also possesses the capacity to inhibit the activation of the EGF-Receptor indicating that it has the potential to break the autocrine loops that are established in several advanced cancers. Studies also suggest that curcumin, resveratrol and green tea can actually be used as safe, non-toxic treatments in drug resistant cancers. These natural phytochemicals (food grade) can help fight certain cancers thereby requiring a smaller dose of drug chemotherapy. They also can protect the body from the damages of drug chemotherapy and radiation. “This mini review presents evidence that chemopreventative agents, curcumin, green tea and resveratrol, can be used not just to prevent cancer but also to treat cancer. Because of their pharmacological safety, most chemopreventative agents can be used in combination with drug chemotherapeutic agents to enhance the affect at lower doses and thus minimize chemotherapy- induced toxicity. Because cancer is primarily a disease of old age, less toxic therapy is a major priority. This review reveals that molecular targets of chemopreventative agents are similar to those currently being used for the treatment of cancer. Tumor cells use multiple cell survival pathways to prevail and thus agents that can suppress multiple pathways have great potential for the treatment of cancer”1,2. Curcumin, resveratrol and green tea were as effective in preventing and treating certain cancers based on lab and animal studies. There have been approximately 20 human positive studies but much more needs to be done. From the research that I have done, I am convinced sufficiently enough to take many of these compounds as a preventative of cancer. These compounds are completely safe and non-toxic even in high doses. What does one have to lose? Why not take the positive preventative measure? –Compliments of Terry Naturally Ref: 1. Role of chemopreventaive agents in cancer therapy. Comprehensive Cancer Center Our Lady of Mercy Medical Center, New York Medical College, Bronx New York 2. Cytokine Research Section, Department of Bioimmuno Therapy, University of Texas, M.D Anderson Cancer Center, Houston Texas
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1748) Take Charge Of Your Health With Herbal Bio-Identical hormones
Date:
November 04, 2007 03:17 PM
Bioidentical hormones assist women in overcoming acute menopausal symptoms, while improving skin. They help by strengthening bones, keeping the mind sharp, promoting energy and well-being, and helping to preserve vaginal tone and resist vaginal dryness. In men, these hormones add energy and vitality, while improving muscle tones and mental sharpness. Bioidentical hormones (BHRT) are exact duplicates of the hormones that are produced by the body. However, they are much more easily metabolized by the body into safe forms of estrogen than their counterparts, which stimulate toxic metabolites. When they are used in physiologic amounts, bioidenticals carry much fewer risks than synthetic hormones. However, despite the fact that research supports their use and proves them safe alternatives to prescription drugs, few physicians are actually using these hormones in their practices. Those patients, who wish to address menopausal and andropause symptoms, or to achieve lifelong hormonal balance in order to prevent illness, often do not know where to go to find a comprehensive bioidentical hormone replacement program. Instead, they read whatever they can to formulate a plan and purchase various products that are available over the counter, often spending precious time and money on programs and products that don’t do what they’re expected to do. One of the most common errors among people is putting together a program based solely on symptoms instead of first checking hormone levels. Symptoms may overlap from one hormone pattern to another. If you try to replace or augment specific hormones without having an accurate test of the levels first, your results will seldom be good. If your doctor is prescribing transdermal hormones, make sure to do a saliva self-test to measure your hormones levels as it is much more accurate and revealing than other types of tests. You can submit your Samples to Mead Labs, where you will actually receive a telephone consultation from a health professional to interpret your results followed by a program of products prescribed especially for you from one of their medical professionals. With your own results, you can learn a lot about the exact state of your hormones instead of blindly guessing from symptoms which may be similar. For example, men may not need testosterone shots or transdermal patches, as the results may show estrogen dominance. The answer for this is not adding more testosterone, because the man could be converting testosterone into estrogen, but instead a program including special herbs and nutrients may be much more beneficial. No matter your gender, your health professional at Mead Labs will design a safe and effective program based solely on bioidentical hormones, herbs, and nutrients first. In the past years, when prescription, non-bioidentical HRT was used by any women with menopausal symptoms, there was no testing to find out what kind of imbalance was actually occurring. Proponents of BHRT are trying to ensure that this method of prescribing the same combination and amounts of medications to everyone is not used with natural hormones. Because hormone profiles and levels can vary significantly from person to person, even those people in the same gender, testing hormones levels and obtaining recommendations from a medical professional who is experienced in BHRT are the key points to ensure you benefit from this therapy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1617) Breast Cancer and Natural Supplements
Date:
May 11, 2007 10:47 AM
Breast Cancer and Nutritional Supplements
There is probably nothing more frightening for a woman than the discovery of a lump in her breast. Cancer and all its consequences quickly come to mind. This quick association may materialize, in part, because no woman is immune. Most have a friend, a sister, a mother, or a coworker who has been diagnosed with the disease. And they know how difficult dealing with this disease can be. Fortunately, 80% of all breast lumps are not cancerous. Most are cysts or a benign clump of tissue.
Over her lifetime, a woman’s breasts undergo many, many changes. From before puberty and on, breast tissue is continually evolving. Breasts often feel different before menstrual cycle, returning to normal a few days after. Pregnancy certainly causes changes in a woman’s breasts, as does breastfeeding. And as women age, breast tissue becomes less dense.
Because of these continual changes, breast tissue especially requires adequate nutrition. While everyone benefits from a healthy diet, there are additional nutrients from which women can specifically benefit.
In this issue of Ask the Doctor, we will discuss breast cancer and the vast amount of research that has explored the role nutrition plays in this serious and still deadly disease. Specifically, we will discuss how two B vitamins, calcium D-glucarate, broccoli extract, green tea, maitake mushrooms, and iodine can all help prevent breast cancer.
Q. How can these nutrients prevent breast cancer?
A. Scientists learn a lot about disease from simply observing what is happening around them. One observation that has been recognized for many years is that certain cultures have very low incidence of breast cancer. Women n
Moms (and dads) have also learned a lot about diseases simply by observing what is happening in their families. They have notices that certain vegetables play a large role in the prevention of all types of diseases, including cancer. And, accordingly, they have been urging their offspring to eat their vegetables for several generations.
Building on these observations, scientists have designed and carried out many studies to determine what it is about these nutrients that can prevent breast cancer. What they have discovered, so far, follows. Let’s start with the B vitamins.
Vitamin B12
Deficiencies of this vitamin can result in a serious type of anemia. Nerve damage can also occur if B12 levels are too low. Researchers are now investigating whether breast cancer may, in part, be caused by a B12 deficiency as well.
At
Another study, this one taking place in a laboratory setting, discovered that vitamin B12, applied directly against experimental breast cancer cells, actually stopped the cancer cells from growing. The researchers conducting the experiment believe that giving vitamin B12 to women with breast cancer as part of a chemotherapy regime, might help keep the cancer in check.
Folic Acid
Low folic acid intake is linked to the development of all cancers. This is because folic acid is crucial to the making and continual repair of DNA, the molecule that carries our genetic code. A recent study discovered that high intakes of folic acid might actually reduce the risk of breast cancer. The researchers looked at the diets of over 2600 women. During interviews with the researchers, the women reported what they usually ate. Once the data was collected, the results showed that women, who ate lots of foods that contained folic acid, had much lower rates of breast cancer.
There is no clear-cut, single cause of breast cancer. Many factors are required for the disease to appear. One such factor is estrogen. A recent study showed that women who developed breast cancer tended to have higher levels of estrogen circulating in their bodies than women without breast cancer. This means that women who got their periods before age eleven or entered menopause after age fifty-five have a higher risk of breast cancer. This also supports the theory that the number of menstrual cycles a woman has affects her risk for breast cancer.
Another factor is drinking alcohol. Because alcohol raises estrogen levels, if a woman consumes even moderate amounts of alcohol her risk of breast cancer also is increased. The link between alcohol and breast cancer may even be stronger than other dietary links. However, an important study has discovered that folic acid may uncouple this link.
A very large study of over 34,000 women recently studied the effect of folic acid on the risk of breast cancer. This project was part of the Nurses’ Health Study, an ongoing, long-term study that looks at nutrition’s role in the development of disease. The women in the folic acid and breast cancer study were followed for 12 years. The participants completed detailed food questionnaires that provided the researchers with important data.
The women were divided into four groups:
1. Women with low folic acid levels and drink alcohol
2. Women with high folic acid levels and rink alcohol
3. Women with low folic acid levels and don’t drink alcohol
4. Women with high folic acid levels and don’t drink alcohol
Within these four groups the women were further divided into subgroups according to the amount of alcohol they consumed each day and their specific folic acid intake.
The researchers found that women who consumed the lowest amounts of folic acid and drank at least one alcoholic beverage a day had the highest rate of breast cancer. In contrast, women who had high intakes of folic acid and also drank at least one alcoholic beverage a day, had the same rate of breast cancer as the women with high folic acid intakes who did not drink. In other words, women who had high levels of folic acid in their diet erased their alcohol-related increase in breast cancer risk.
Calcium D-Glucarate
It seems estrogen can be both friend and foe. While women need the hormone to soften skin, thicken hair, and fill out hips and breasts, estrogen can also nourish breast tumors, helping them grow bigger, stronger, and more deadly. Thanks, in part, to good nutrition, American women get their periods early and go through menopause alter in life. Women today also have fewer pregnancies; families with one or two children are quite common.
All of these factors increase the time women’s bodies are exposed to estrogen. As we discussed before, longer exposure means increased opportunities for estrogen to cause trouble. It is also a troubling fact of modern life that we are continuously exposed to cancer-causing chemicals and toxins. These toxins come in part from contaminants in the food we eat and pollutants in the air we breathe.
The body does have a system that eliminates some of the excess estrogen and toxic chemicals before they can cause harm. In the liver, they are bound or attached to a chemical called glucuronic acid. The bound toxin or estrogen is then excreted in bile and eventually eliminated as a waste product in the stool.
However, an enzyme called beta-glucuronidase can break this bond between estrogen and glucuronic acid. When this happens, the hormone or toxin is released from its bone, capable of causing harm once more. Increased beta-glucuronidase activity is associated with an increased risk for various cancers, particularly hormone-dependant cancers like breast cancer.
Fortunately, scientists have discovered that a natural substance found in foods calcium D-glucarate (CDG) can stop the activity of beta-glucuonidase. CDG keeps the harmful estrogen bound to glucuronidase. While CDG is found in fruits and vegetables, the amounts may not be sufficient to maintain effective levels to stop beta-glucuronidase.
CDG has been shown in experimental studies to significantly stop beast cancer growth. And several human trials are currently underway with CDG to determine its capability to decrease the breast cancer risk in women at high risk for the disease.
Iodine
There are some very interesting connections between breast tissue and thyroid tissue. Iodine is an essential trace element present in a hormone of the thyroid gland and is involved in several metabolic functions. One iodine function is the protection of breast tissue from cancerous cells.
In a laboratory study, researchers exposed breast cancer cells and breast tissue without any cancer to a type of seaweed that contains high levels of iodine. The seaweed killed all of the cancerous cells, yet did not harm the normal breast cells. Japanese women frequently eat this type of seaweed and have very low rates of breast cancer. The study’s researchers believe one reason for this low incidence of breast cancer may be the iodine in the seaweed.
And, for some as yet unknown reasons, women who have thyroid cancer are at higher risk of developing breast cancer. While they are unsure why this happens, researchers are continuing to study this link, and support of healthy thyroid function remains an important consideration.
Broccoli
For quite some time, scientists have observed that cruciferous vegetables, such as broccoli, cabbage, and cauliflower, significantly reduce the risk of disease, including cancer. It seems a phytochemical in broccoli sulforaphane, is one of the chemicals responsible for this beneficial activity. Sulforaphane increases certain enzymes in the body called phase 2 enzymes that deactivate cancer-causing chemicals.
Breast cancer cells exposed to sulforaphane in several lab experiments showed that the compound inhibited the growth of the cancer cells up to 80 percent. Researchers are in the process of setting up clinical trials to study sulforaphane’s effect in women who have breast cancer.
Green Tea
There is a tall amount of research, including finding from the Nurses’ Health Study, that suggest green tea beverage consumption is associated with a lower incidence of breast cancer. In fact, researchers have long noted the low rates of breast cancer in
The active compound in green tea responsible for breast cancer inhibition is epigallocatechin-3 gallate or EGCG. When breast cancer cells are exposed to EGCG in lab experiments, the cells stop growing, lose their ability to replicate, and die.
In a recent study, researchers discovered that drinking green tea prevented the recurrence of breast cancer in women who have previously been diagnosed and treated for the disease. This study involved over 1100 Japanese women. The women who drank green tea every day had very low rates of their breast cancer returning.
Maitake Mushrooms
For thousands of years, maitake mushrooms have been linked to good health in those who eat them. Called “dancing mushrooms” (possibly due to their wavy, rippling appearance or possibly due to the little dance of joy mushroom hunters perform when they find them in the woods), maitakes contain an important compound called D-fraction.
Not only does the D-fraction in maitake mushrooms stop the growth of cancerous tumors, it also alerts and stimulates immune cells (including macrophages and natural killer cells) to fight the disease. Maitake also inhibits some of the mechanism that promotes metastasis, or spread, of cancer cells in the lymph and bloodstream.
Because of this success, maitake is now being used in clinical trials of women with breast cancer. One study reported significant improvement of symptoms, including reduction of the tumor. The maitake was given to breast cancer patients in addition to standard chemotherapy.
Q. Should these nutrients be used in place of traditional treatment for breast cancer?
A. Absolutely not. None of these nutrients can cure breast cancer. However, they can be a part of a validated plan of treatment. If you have breast cancer, talk to your health care practitioner about these nutrients. Remember, nutritional supplements are just that: supplements to food, medication, and treatment. They are intended to enhance and prevent, not replace.
Conclusion
Despite apprehension in performing self-breast exams, women are very proactive in their health. Yearly mammograms and pap tests have been an important part of their lives for many years, and newer and more accurate diagnoses are emerging. The prevention of health problems in themselves and their families has always been a high priority for women. And for women, nutrition has played an important part of health problem prevention.
Nutritionally speaking, what benefits your breasts benefit your whole body. However, as we have learned, there are specific links between nutrition and developing breast cancer that seem to be fairly strong.
Making a few changes may reduce the risk of developing the disease. The nutrients listed here, vitamin B12, folic acid, calcium d-glucarate, iodine, broccoli, green tea, and maitake mushrooms can be an important part of a woman’s preventative health regimen.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1537) Memory And Focus
Date:
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Like
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood Samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Conclusion
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1533) D-Ribose Powder Benefits!
Date:
April 10, 2007 11:57 AM
Supports normal heart function*
A significant amount of in vitro, animal and human research suggests benefits of ribose on heart function.* Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism.* Ribose has been shown in clinical trials to enhance the recovery of heart muscle ATP levels and improve myocardial function following exercise.
Studies suggest that ribose supplementation can increase the tolerability of the cardiovascular system to exercise-induced fatigue.1 In one study, twenty men underwent treadmill exercise tests on two consecutive days to confirm the onset of fatigue secondary to exercise. The participants were then randomized to the treatment group or a placebo group. The groups received either four doses of 15 grams of D-ribose (60 grams/day total) or the same amount of placebo each day. After three days of treatment, another treadmill test was performed. The time it took to reach the specified level of fatigue was significantly greater in the ribose group than in the placebo group.
Another study investigated the ability of ribose to support healthy heart function and quality of life.2 In a randomized, crossover design study, fifteen individuals were given 5 grams three times a day of either D-ribose or placebo. Each treatment period lasted three weeks. In patients receiving ribose, echocardiography demonstrated enhancement of heart function, reflecting a “more efficient relaxation phase of the heart”. Participants also had a significant improvement in their subjective quality of life scores compared to placebo.
Scientists suggest that suboptimal heart function is a result of the heart requiring more energy to function properly. Ribose supports the heart’s enhanced energy requirements, promoting optimal heart function. It does so by enhancing the stores of high-energy phosphates in heart tissue. These intermediates are necessary for the production and resynthesis of ATP. A double-blind crossover study in which 12 individuals were randomized to receive either ribose or dextrose (both administered as 5 grams three times daily for three weeks, followed by a 1-week washout period and crossover of treatments for three additional weeks) suggested significant enhancements in normal cardiac function during the period of ribose supplementation.3
Perhaps one of the more useful illustrations of the potential for ribose to support heart function comes from a study in which 20 rats received a continuous infusion of ribose for 24 hours (control rats received an infusion of saline). The hearts were then explanted (as they would be for heart transplants) and placed in preservation solution that was enriched with ribose for 4 hours. ATP levels were measured from tissue biopsies and revealed that 10 of the ribose-treated hearts had ATP levels higher than 12.3 micromoles per gram whereas saline-treated hearts (controls) had lower ATP levels, with 20% showing levels below 10 micromoles per gram of tissue. This provides support for the hypothesis that ribose may enhance the preservation of ATP levels in cardiac tissue, promoting normal heart function.4
Further animal studies have shown that ribose significantly enhances heart function after experimentally induced cardiac depression. Rats were injected with isoproterenol (a drug that stimulates sympathetic nervous system function) and had their abdominal aorta constricted to induce depression of heart function and reduce cardiac ATP levels. The decrease in ATP was primarily responsible for the depression of heart function. Continuous infusion of ribose for 24 hours replenished ATP concentrations to normal levels and normalized heart function in these animals.5
Ribose may strengthen and support the body’s crucial antioxidant defenses*
Ribose may support the body’s innate antioxidant mechanisms while promoting an antioxidant effect of its own. Intense exercise and other strenuous activity can induce the production of free radicals. Preliminary studies suggest that ribose can attenuate some of the effects of oxidation seen after performance of intensive exercise.
One small human study indicated that ribose administered at a dose of seven grams before and after a bout of cycling exercise may reduce free radical production.6 Seven volunteers ingested either ribose or placebo both before and after intense exercise. Markers of lipid peroxidation, including malondialdehyde, significantly decreased in the ribose-supplemented group, while increasing in the control group. The results of this study indicate a possible effect of ribose in supporting antioxidant activity.
Supports healthy energy levels in heart and muscle tissue*
After bouts of intense exercise, ATP levels have been shown to decrease by an average of 15 to 20%.7 The amount of ATP stored in the muscle is limited and so the body must have the potential to rebuild ATP stores. ATP is the fuel necessary for the integrity and function of a cell. In addition, several studies have found correlations between ATP content and heart function.1 Research that was also alluded to above suggests that ribose stimulates ATP synthesis and supports heart and muscle function by enhancing ATP levels in cardiac and muscle tissue. D-ribose is an essential building block for the synthesis of ATP through the pentose phosphate pathway.
The results of ribose supplementation enhancing ATP levels in muscle are evidenced by studies suggesting beneficial effects on anaerobic performance. In a randomized, placebo-controlled crossover study assessing the effects of acute ribose supplementation, participants receiving the ribose supplement had increases in mean power (a measure of average overall muscular strength output during the sprint) and peak power (a measure of the highest muscular strength output during the sprint) when undergoing a series of cycle sprints.8 While this effect was not noted in all of the six short cycling sprints that the participants underwent, the study does illustrate the potential benefits of ribose on ATP production and, secondarily, on enhancing exercise performance.
A second placebo-controlled trial investigated the effects of four weeks of ribose-supplementation (10 grams /day) on male bodybuilders. Of the 20 participants who were recruited, twelve completed the study. Each subject participated in a heavy-resistance training program designed to increase skeletal muscle mass. The effects of ribose on body composition (body weight, body fat, lean body mass, fat mass, and bone mineral content) were also assessed. The results suggested that ribose increased total work capacity and bench press strength compared to placebo, without altering body composition.9
Supports energy recovery after exercise*
Animal studies have suggested that the administration of ribose after exercise increases the rate of adenine salvage by five to seven-fold in muscle tissue7, supporting energy recovery after exercise. When ATP is utilized by muscle tissue, the degradation products include adenine nucleotides (Adenine is one of two purine bases that is a component of DNA). Adenine is recycled to synthesize DNA, and the salvage of adenine within the muscle tissue is crucial to energy recovery. Studies have shown that the presence of adequate ribose concentrations is the rate-limiting step in the purine salvage pathway. Therefore, increased adenine salvage could potentially help in the recovery and regeneration of ATP after intense bouts of activity.
A study investigated the effect of oral intake of ribose on the synthesis of AMP, a precursor to ATP.10 Participants performed intense cycle training for seven days. They then received either ribose (at a concentration of 200 mg/kg body weight, which is equivalent to 14 grams per day for an average 70 kilogram male) or placebo three times a day for the following three days. Exercise tests were performed again on day 4. Muscle biopsy Samples were taken before the first training session, immediately after, and again five hours, 24 hours, and 72 hours after the last training session. No differences were seen in exercise performance between the groups. The intense exercise caused the ATP levels in muscle to decrease in both groups. However, at 72 hours post-exercise, the ribose group exhibited a much higher ATP level than the placebo group. The muscle levels of critical building blocks for ATP, including total adenine nucleotides (TAN) and inosine 5’-monophosphate (IMP), were also significantly higher in the ribose group compared to the placebo group at 24 hours after exercise. Ribose-supplementation was shown to enhance the resynthesis of ATP after intense exercise.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Safety
Caution: Insulin-dependent diabetics and pregnant women should consult their physician before use.
Suggested Adult Use: Take 1 or 2 scoops mixed in water, juice or other beverage two times per day. May be taken with or without food.
Scientific References
1) Pliml, W., von Arnim, T., Stablein, A., Hofmann, H., Zimmer, H., Erdmann, E. Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. The Lancet. 1992;340:507-510.
2) Omran, H., Illien, S., MacCarter, D., St. Cyr, J.A., Luderitz, B. D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study. The European Journal of Heart Failure. 2003;5:615-619.
3) Illien, S., Omran, H., MacCarter, D., St. Cyr, J.A. Ribose improves myocardial function in congestive heart failure. FASEB Journal 2001;15(5): A1142
4) Muller C., Zimmer H., Gross M., Gresser U., Brotsack I., Wehling M., Pliml W. Effect of ribose on cardiac adenine nucleotides in a donor model for heart transplantation. Eur J Med Res. 1998 Dec 16;3(12):554-8.
5) Zimmer H.G. Normalization of depressed heart function in rats by ribose. Science. 1983 Apr 1;220(4592):81-2.
6) Seifert, J.G., Subudhi, A., Fu, M., Riska, J.J. The effects of ribose ingestion on indices of free radical production during hypoxic exercise. Free Rad Biol Med 2002; 33(Suppl 1) S269.
7) Zarzeczny, R., Brault, J.J., Abraham, K.A., Hancock, C.R., Terjung, R. Influence of ribose on adenine salvage after intense muscle contractions. J Applied Physiology. 2001;91:1775-1781.
8) Berardi J.M., Ziegenfuss T.N. Effects of ribose supplementation on repeated sprint performance in men. J Strength Cond Res. 2003 Feb;17(1):47-52.
9) Van Gammeren, D.V., Falk, D., Antonio, J. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy, young, male recreational bodybuilders: a double-blind, placebo-controlled trial. Current Ther Research. 2002;63(8):486-495.
10) Hellsten, Y., Skadhauge, L., Bangsbo, J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. 2004;286:R182-R188.
-- Buy Ribose at Vitanet at a Discount
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1510) EpiCore Benefits
Date:
April 09, 2007 05:02 PM
EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in
Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.
Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*
A comparison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4
NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2
High Metabolite Immunogen*: Nutrient Make-up
Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2
Beneficial Antioxidant Activity*
EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5
In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2
Safety
Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3
In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.
The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1
Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine Samples were analyzed. No clinically relevant abnormal effects on the participants were found1.
EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.
EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Scientific References
1. Embria Health Sciences
2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.
3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the
4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.
5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1508) Revita
Date:
March 08, 2007 12:27 PM
Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product. Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class. To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules. Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth. Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available. Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects. In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls." In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded: • The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls. • 78.9% of subjects showed an increased mean value of hair diameter. • "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness." Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results. Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings: • Total Number of Hairs: Significantly Increased • Total Number of Terminal Hairs: Significantly Greater • Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher • Hair Follicle Activation: Intensive In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials. Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss. Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area. The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp. Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles. Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E. Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth. Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing. Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial. If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months. Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study. The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo. Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion. After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier. Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss. MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM. The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes. MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications. Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness. The independent study at the University of Jena used hair Samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing Samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone. According to the research, the results showed that the Samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss. The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study. Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate. Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate. The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased. Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft. Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids. Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth. L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications. The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth. Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day. In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing. Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic. Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth. Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle. Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss. After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week. This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted. Q. Is Revita safe ? A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe. Q: Can I use hair sprays, mousses, gels, etc.? A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita. Q: Can I have my hair colored or permed while using Revita ? A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita. Q: What is SLS/SLES free ? A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health. Q: Can I blow dry my hair after using Revita ? A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita. Q: Who is a candidate for Revita ? A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately. Q: What type of results should I expect with Revita ? A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment. Q. Does Revita have any systemic side effects ? A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically. Q. Does Revita work for women? A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair. Q. I am using other topical treatments. Can I use Revita at the same time ? A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair. Q. Do I need to use Revita for a long time ? A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp. Q: Is stress a factor in hair loss? A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1480) Soft Drinks Contaminated by Benzene
Date:
May 27, 2006 09:24 AM
A Food and Drug Administration (FDA) testing program has found cancer-causing benzene in soft drinks at levels averaging four times the standard for tap water. The brand names have not been released. The test data were uncovered by the Environmental Working Group (EWG), which posted the test results on the group’s website, www.ewg.org Highly elevated Benzene Levels Between 1995-2001 the RDA tested 24 Samples of diet soda for benzene. The result: 79% tested at levels above the federal limit for benzene in tap water, which is 5 parts per billion (ppb). The maximum benzene level detected was 55 ppb. In addition to the diet sodas, the FDA tested a number of other non-diet soft drinks. One cola was contaminated at 27 times the tap water limit, and fruit drink had a 95 ppb level. “These results confirm our suspicions there are highly elevated benzene levels in some very popular drinks,” Richard Wiles, EWG’s senior vice president said in a press release. Reaction Triggered by Preservatives According to an article in beveragedaily.com, sodium benzoate and ascorbic acid in soft drinks can react together to form benzene. Sodium benzoate is a common preservative in soft drinks, and ascorbic acid is often added as an antioxidant to extend shelf life. Negotiations between the FDA and the beverage industry in 1990 resulted in an agreement that the industry would voluntarily reformulate its soft drinks to prevent this combination. The recurrence of benzene contamination may be due to new soft drink manufacturers in the market who were not a part of, or aware of, the original negotiations. Britain Pulls Soft Drinks from Shelves In contrast to the U.S. situation, food safety campaigners in England were successful in having benzene –containing soft drinks removed from the supermarket shelves. The British Food Standards Agency pulled four soft drink brands which contained more than 1 ppb of benzene, and rushed out the results of tests on 149 drinks, including a range of fruit juice, iced tea, squash, fizzy and low-sugar drinks, according to The Times of London. The Wellness Revolution and Contaminated Soft Drinks The controversy over benzene in soft drinks is an example of how toxic exposure exists in our food and immediate environment. The constant exposure to toxics were-and especially our children—experience is a major cause of chronic illness. In this situation, the organic products available for purchase in health food stores are especially vital. And since some exposure to toxics is unavoidable we must take advantage of the herbs and nutrients that support detoxification and the liver, the main organ of detoxification, as well as immunity for example, silymarin, N-acetyl cysteine, calcium D-glucarate, folic acid, Reishi and shiitake mushrooms, and turmeric. Sources: www.ewg.org www.beveragedaily.com 02/25/06. Associated Press 04/11/06. www.fda.org. Public Pressure Forces Corporations to Curtail Most Soda Pop sales to schools The Nation’s largest beverage distributors have agreed to halt nearly all soda sales to public schools, according to a deal announced may 3rd by the William J. Clinton Foundation. The companies have agreed to sell only water, unsweetened juice and low fat milks to elementary and middle schools, according to a spokesman for former President Bill Clinton. Diet sodas would be sold only to high schools. The deal follows a wave of criticism by school districts and state legislatures amid reports of rising childhood obesity. Soda has been a particular target because of its caloric content and popularity among children.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1284) Best Sugar Balance Svetol (green coffee extract)
Date:
May 05, 2006 06:30 PM
Ingredients Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids. In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.* Benefits Maintains healthy blood sugar levels when used as a part of the diet* CHLOROGENIC ACIDS Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1 Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the Samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee Samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee Samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3 Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5 It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism. A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood Samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6 RESEARCH ON SVETOL® Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results. In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7 Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption. The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.* SAFETY Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7 *This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4. 2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402. 3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7. 4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10. 5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15. 6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1258) Acai is an exotic palm fruit from the Amazonian rain forest!
Date:
February 12, 2006 01:38 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1215) Maintains Healthy Immune Function *
Date:
February 11, 2006 09:29 AM
Goji berries contain a unique profile of polysaccharides that work together to impact cell-signaling functions, thereby facilitating immune cell communication. Along with its antioxidant activity, Goji berry extract has the ability to maintain healthy immune function.* The polysaccharide complex of Goji berry seems to be a powerful immune stimulator. Preliminary studies indicate that these polysaccharides may have wide-ranging benefits to immune health. One such study showed that certain polysaccharide components of Goji berry had the ability to influence cytokine production in human PMN cells (a class of white blood cells) when the extract was exposed to human blood Samples. These effects suggest an immune-enhancing action of the polysaccharide fraction tested.6 A second study conducted in mice tested the immune-modulating effects of the same polysaccharide fraction of Goji berry in these animals. Goji berry extract, given orally once daily for ten days, was shown to influence a wide variety of immune parameters, favoring both humoral and cellular immune responses in a beneficial fashion. This was accomplished, in part, through up-regulation of cytokine and antibody production in these animals after administration of the polysaccharide extract. These changes were not seen in the control group.7 Goji berry extract has the ability to promote health through its immune-enhancing and antioxidant qualities.* Research into mechanisms of action are revealing that this ancient food, revered as a health tonic for centuries, may hold great importance for supporting the health and function of a number of bodily organs and systems.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1213) Potent Antioxidant Protection *
Date:
February 11, 2006 09:28 AM
Goji berry possesses a unique combination of flavonoids, vitamins, minerals and polysaccharides that are thought to be responsible for the antioxidant and anti-aging properties attributed to Goji. Studies have been conducted which characterize some of these antioxidant nutrients and show possible beneficial effects of the berry and its extracts on various systems and organs. In a study published in 2004, scientists undertook an experiment to assess whether Goji berries contained compounds that would be known to exert potential beneficial effects on skin complexion and anti-aging properties. After analyzing the berry, leaf and roots of the Goji plant, they found that the Goji berry contained a unique analog of vitamin C known as 2-O-(beta-D-glucopyranosyl) ascorbic acid. They determined that this compound was unique to the berry and not found in the other parts of the plant. Furthermore, the vitamin C compound was present in levels equivalent to those found in citrus fruits such as lemons. However, the question remained as to whether this vitamin C analog served as a precursor to vitamin C when ingested in the body. A further experiment in rats was performed to determine the intestinal absorption and tissue uptake of this vitamin C analog. The results showed that some of the compound was indeed metabolized into vitamin C in the blood, while the rest was absorbed intact. These studies suggested that the compound was easily transported from the blood into cells and tissues, where it is activated to active vitamin C. Therefore, the vitamin C from Goji berries seems to be highly absorbable and targeted for delivery to the cells that utilize it.1 Zeaxanthin is a carotenoid that is widely distributed in fruits and vegetables and, along with lutein, is present in significant amounts in the macula of the human eye. Studies suggest that the presence of zeaxanthin is highly desirable for healthy visual function. Goji berries are used in traditional Chinese herbalism to support eye health and are also known to contain a high level of zeaxanthin dipalmitate. Researchers compared the bioavailability of this naturally esterified zeaxanthin to that of an unesterified form in 12 individuals who underwent a 23-day study in which they received one form or the other, and then switched. Administration was done on day one followed by a three-week washout period. The individuals were then crossed over to get the other form on day 23 in a single administration. Analysis revealed that the esterified zeaxanthin from Goji berry caused a higher increase in plasma levels than the non-esterified form, indicating higher bioavailability.2 A second study confirmed these findings. In this study, fourteen individuals consumed 15 grams of whole Goji berries daily for 28 days. These individuals were compared to thirteen age and sex-matched controls who did not consume the berries. Fasting blood Samples were taken for all individuals before and after the 28-day period. Results indicated that zeaxanthin plasma levels increased 2.5-fold in the group who consumed the berries daily, suggesting the high bioavailability of zeaxanthin from the berries.3 Goji berry was also studied on various measures of antioxidant activity. Researchers subjected three Chinese herbs, one of which was Goji berry, to various assays of reactive oxygen scavenging potential. The results indicated that all of the herbs had significant free radical scavenging properties; however, Goji berries showed the most potent scavenging effect in the assays. Goji berry was especially strong at inhibiting the formation of superoxide anion and scavenging free radicals. The researchers concluded that among these herbs, Goji could be considered the best antioxidant to promote healthy aging.4 An interesting study was performed in human skin cultures to determine the mechanism of the potentially protective effect of Goji berry extracts. Researchers found that bathing human skin cultures with an extract from Goji berry impacted the function of several enzymes that promote skin aging. This provides evidence of an anti-aging and antioxidant effect of Goji berry extract in these human skin cultures. Researchers also noted that when these skin cultures were subjected to suboptimal growth conditions (lack of adequate nutrients), supplementing the medium with this Goji berry extract allowed the skin to maintain normal metabolic functions.5 Goji berry extract contains numerous compounds that confer potent antioxidant protection to various tissues.*
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1212) Now Foods -QUALITY- High Standards and Attention to Detail
Date:
December 27, 2005 09:00 AM
QUALITY “High Standards and Attention to Detail”
As you shop for dietary supplements you’re faced with an almost dizzying array of choices. Naturally, every product claims to be this, that and the other. But you’ve heard the stories in the media of products that don’t live up to their claims. So how do you know who’s telling the truth? Perhaps a better gauge of a product’s quality is the manufacturer and their history. Do they have a legacy of producing quality goods? How long have they been in business? Is their track record good or do they have a history of product recalls and bad press? If you’re responsible for your family’s health and well-being, it pays to do your homework when it comes to the products you purchase for them. NOW® Foods has been manufacturing dietary supplements and whole foods for 35 years. Companies that thrive and continue to grow for this long don’t do so because they produce poor quality products. They do so by maintaining extremely high standards and paying special attention to every detail, which is the secret to product quality. At NOW® Foods, these high standards and attention to detail are evident in every aspect of our operations, from receiving to production to finished goods, just as they have been for 35 years. You’re committed to buying only the best for your family, and we’re committed to supplying only the best for our customers. Quality products are made using the highest quality ingredients. NOW Foods purchases raw materials from only the most reputable vendors, who are required to provide detailed specification sheets and lot-specific certificates of analysis for every shipment we receive. These documents provide information on the quality of the raw material and the various analyses used to verify that quality. Shipments that do not meet our quality standards are sent back to the manufacturer with a point by point report card of why the shipment was refused. We simply don’t just accept every shipment that’s delivered to our dock – no ingredient gets a free pass into our production facility. In addition, we also perform random vendor audits throughout each year to ensure that they’re meeting our stringent quality standards. NOW ® Foods is always vigilant when it comes to quality, just as you are. Another way we maintain high quality standards is by choosing to buy and incorporate registered and/or trademarked ingredients into our products. Each of these ingredients are exclusively produced by a company that owns proprietary manufacturing rights and licenses selected companies like NOW® to use these top quality ingredients in their products. These registered/trademarked ingredients must undergo even more rigorous analysis and controls than other ingredients, and so offer additional assurance that products containing them are properly manufactured and labeled. Additionally, to maintain the integrity of their ingredient’s reputation, the trademark owner will independently test finished products from manufacturers to verify the quality meets their standards and the label claim of the company licensed to use it. You may be familiar with some of the trademarked ingredient NOW® uses such as, Ester-C® vitamin C, Chromemate® Chromium and L-Carnipure® Carnitine. Scientific analysis of ingredients is extremely important to ensure the integrity of any dietary supplement. NOW Foods has made substantial investments in the development, construction and staffing of numerous inhouse laboratories, including an advanced instrumental analysis laboratory, a “wet lab” and a state-of-the-art microbiology lab. This saves us the time and expense of having to send Samples out to commercial labs for analysis. While we use independent labs to verify our in-house test results, our capabilities allow us greater control over product quality and quicker approval of raw material shipments for production, which means fresher products for consumers. Our investment ensures that NOW® will be able to meet ever-increasing demands for accurate product analysis and outstanding product quality. NOW® is unique in the industry in that we annually spend more on Quality Assurance & Control than we do on Marketing and Advertising combined. What good is a lab without qualified people? NOW® employs an expert team of highly qualified scientists and technicians, including four Ph.D.’s. They’re constantly working to develop new and improved analytical methods, and their efforts contribute not only to our product quality but that of the entire industry as well. This is all great, you say, but what about your facility and the equipment you use to manufacture products? Our 203,000 square foot facility is designed and built to standards that exceed food-packaging guidelines. It supports pharmaceutical-grade operations, which greatly enhances our ability to produce the highest quality products quickly. All this means fresher, more effective products on store shelves for consumers. NOW® Foods is an ‘A’ rated GMP-certified manufacturer, one of the first companies in the industry to attain GMP (Good Manufacturing Practices) certification. We’re also certified by QAI (Quality Assurance International) as an organic manufacturer. As consumers become increasingly demanding of supplement quality and safety, NOW® is ready to meet this demand with sound science and state-of-the-art research, manufacturing, and packaging capabilities. We are certain that our efforts to consistently maintain the highest product quality will help make your natural product purchasing decisions easier.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1082) VitaBerry Plus+ Fact Sheet
Date:
December 07, 2005 05:38 PM
VitaBerry Plus+ Fact SheetNeil E. Levin, CCN, DANLA 3/18/05LIKELY USERS: Antioxidant users who want the best food source formula; People seeking polyphenols or ellagic acid supplements; Those who don’t eat fruit and want some of their benefits KEY INGREDIENTS: VitaBerry extract, Hi-Active Orange Extract, Pomegranate Extract (420 mg) (400 mg) (100 mg) MAIN PRODUCT FEATURES: This is a high antioxidant (high ORAC: 2,500 units per serving of oxygen radical absorbing capacity), proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry extract, Grape & Grape seed extract, Raspberry & Raspberry seed extract, Cranberry, Prune, Tart Cherry, Wild Bilberry extract & Strawberry powder. Fortified with Hi-Active Orange Extract (Freeze-dried Orange (Citrus sinensis) powder with minimum of 40% vitamin C) and Pomegranate Extract (80% Polyphenols and 40% Ellagic Acid). Provides a broad-spectrum antioxidant blend with phytochemicals such as anthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol etc. in a single “0” size vegetarian capsule. There is a synergistic effect of mixing fruit antioxidants that provides antioxidant protection greater than is predicted by measuring each fruit source used in the mix individually. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: There will be some natural variation in color, taste and odor from these fruit sources. A special freeze drying technique preserves the antioxidant value of whole fruits in a concentrated form. SERVING SIZE & HOW TO TAKE IT: Serving is 2 Vcaps. Take one or more servings per day as an antioxidant supplement. May be taken with food or on an empty stomach (this is food). COMPLEMENTARY PRODUCTS: All antioxidants. CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This information has not been reviewed by the FDA or the company posting it. Information given here may vary from what is given on the product label because this page represents my understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc). 2004 Jan;69(1):75-80, 1 p preceding 75. Review. PMID: 14972022 Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 2002 Jul 15;22(14):6114-20. PMID: 12122072 Huang D, Ou B, Prior RL. The Chemistry behind Antioxidant Capacity Assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-1856. PMID: 15769103 Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. PMID: 12323088 Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002 Dec 18;50(26):7731-7. PMID: 12475297 Prior RL, Cao G. Analysis of botanicals and dietary supplements for antioxidant capacity: a review. J AOAC Int. 2000 Jul-Aug;83(4):950-6. Review. PMID: 10995120 Prior RL, Cao G. In vivo total antioxidant capacity: comparison of different analytical methods. Free Radic Biol Med. 1999 Dec;27(11-12):1173-81. Review. PMID: 10641708 Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch-Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food Samples. J Agric Food Chem. 2003 May 21;51(11):3273-9. PMID: 12744654 Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33. PMID: 11999391 Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31. PMID: 12448828 Sofic E, Rustembegovic A, Kroyer G, Cao G. Serum antioxidant capacity in neurological, psychiatric, renal diseases and cardiomyopathy. J Neural Transm. 2002 May;109(5-6):711-9. PMID: 12111462 Stintzing FC, Stintzing AS, Carle R, Frei B, Wrolstad RE. Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem. 2002 Oct 9;50(21):6172-81. PMID: 12358498
Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37. PMID: 15186133
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=991) The wellness Revolution - 90% Of Americans Carry Chemical Stew in their Bodies.
Date:
October 01, 2005 01:22 PM
The Wellness Revolution90% of Americans Carry Chemical Stew in their Bodies The third national report on human exposure to Environmental Chemicals, issued this summer, shows that most people in the U.S., and especially children, carry a dangerous mixture of chemicals in their bodies. Nevertheless, the Center for Disease Control (CDC), authors of the report, issued a press release focusing on progress made in a few areas—and most media looked no further than the optimistic press release. The CDC sampled the blood and urine of thousands of subjects across the country for 148 environmental chemicals. This study found a significant decline since previous reports in exposure to secondhand smoke and in lead levels in children’s blood. Despite the positive headlines, however, the study documented the presence in human bodies of dozens of pesticides and toxic compounds used in consumer products. Among the findings: Body Burden and the wellness Revolution This Study—the latest indication that all of us carry a “body burden” caused by widespread chemical use in our society—shows the need for a system that relies on organic agriculture and alternative pest controls. The constant exposure to toxics we experience today is a major cause of chronic illness, including cancer, birth defects or abnormal development, brain or nervous system damage, hormonal and reproductive imbalances, and impaired immunity, to name just a few. Meanwhile, individuals should take advantage of the organic products available in health food stores, and the herbs and nutrients that support detoxification and the liver, the main organ of detoxification, as well as immunity—for example, silymarin, N-acetyl cysteine, calcium d-glucarate, folic acid, Reishi and shiitake mushroom, and turmeric. A healthy lifestyle and appropriate supplementation can offer some protection from societal pollution. Sources: Third National Report on Human Exposure to environmental Chemicals, 2005, available at www.cdc.gov. Los Angeles Times, 7/22/05. A Brief Companion to CDC’s 2005 National Exposure Report, Physicians for Social Responsibility, www.psr.org. Pesticide action network, www.panna.org.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=805) Source Naturals - Continuous Quality Assurance
Date:
August 20, 2005 11:44 AM
“I oversee all the inspections, tests, and document reviews performed by our dedicated Quality Control staff to ensure that nothing compromises the healthfulness and high quality of our products.” Norm Nelson, Ph.D., Quality Control Director Continuous Quality Assurance Our Quality Control Department includes staff trained in microbiological assays, heavy metal screening, analytical chemistry and Eastern and Western herbalism. They utilize procedures that go beyond minimum industry requirements to ensure product excellence. All raw materials and finished goods must meet our inspectors’ rigorous quality specifications at every stage of manufacturing. Pure Raw Materials Bulk raw materials must be accompanied by Certificates of Analysis provided by the vendors. They are sampled and inspected according to a long list of specifications, including appearance, color, odor, flavor, texture, absence of extraneous material, and potency of active constituents. Vitamins, minerals and amino acids are screened and/or tested for impurities, while materials, such as herbs, that are biological in origin are tested for microbiological contamination. Bioavailable Manufactured Product Inspectors scrutinize finished tablets to see that they meet our standards for consistency in size, color, aroma or taste, are not broken, and contain no contaminants. Representative Samples are taken to verify potency. Tablets and capsules are tested to ensure they are consistent in size and comply with USP standards for weight variation. Threshold utilizes USP disintegration standards* as its guidelines to ensure tablets will break up appropriately after ingestion, making the ingredients available for use by your body. *Under USP 25 standard conditions: Coated tablets: 50 minutes in water. Capsules: 45 minutes in buffered acetate or water. Rigorous Laboratory Procedures Methods used include: HPLC (High Performance Liquid Chromatography), IR (Fourier Transform Infrared), UV/Vis Spectrophotometry, Graphite Furnace Atomic Absorbance Spectroscopy, TLC (Thin Layer Chromatography), Microbiology testing, and organoleptic inspection including visual, color, odor, clarity, pH, and taste. Raw materials must comply with vendor Certificates of Analysis as well as with our rigorous specifications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=737) Urinary problems are a common sign that prostate cancer has advanced.
Date:
July 27, 2005 03:30 PM
9. Urinary problems are a common sign that prostate cancer has advanced. In its early, most treatable stage, prostate cancer usually does not cause any symptoms. If prostate cancer develops and is not treated, however, symptoms can include difficult, frequent or painful urination; sexual problems; and pain or stiffness in the lower back, hips, or upper thighs. Following a PSA and a manual exam, a physician should order an ultrasound and X-rays to determine the cause of the symptoms, according to the National Institutes of Health. To confirm the presence of cancer, needles are used to remove small tissue Samples from the prostate. If a biopsy confirms cancer, a rating system called the Biopsy Gleason score is used to measure the aggressiveness of the cancer before a treatment plan is determined.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=708) GARLIC AND CHOLESTEROL LEVELS
Date:
June 25, 2005 10:00 AM
GARLIC AND CHOLESTEROL LEVELS Several controlled studies have conclusively proven Garlic’s ability to lower blood serum cholesterol levels.6 Dozens of these studies conducted throughout the world have compared high fat diets with garlic and without and their resulting cholesterol counts. When Garlic is consistently consumed, the lowest cholesterol levels are obtained.7 Apparently, the allicin compounds in garlic help to block the creation of cholesterol. Consequently, serum-triglycerides and betalipoprotein levels were lowered while HDL levels (good cholesterol) were raised. The way in which garlic accomplished this specific action is not totally understood. What is known is that the presence of Garlic provides a simple restriction in the rise of blood cholesterol and lipid levels. For anyone with a tendency to develop atherosclerosis, these findings are highly significant. When administered in therapeutic dosages, garlic protected the arteries against atherosclerotic lesions. The implications of studies such as this one are that ingesting garlic on a regular basis may have significant value for anyone suffering from heart disease due to hardening of the arteries. Garlic clearly suppresses cholesterol synthesis in the liver by lowering total serum cholesterol. It appears to accomplish this by inhibiting the synthesis of harmful LDL cholesterol which boosts the amount of beneficial HDL cholesterol in the blood. An added bonus of garlic is that some of its chemical components also keep the liver from producing its own cholesterol.8 Laboratory rats whose diets were supple-mented with garlic not only had fewer lipids in their blood and tissue Samples, but less cholesterol and triglycerides in their livers as well. Interestingly, the sugar factor plays a role in cholesterol production and garlic can also be of benefit here. Excess sugar is metabolized into materials which are required for the making of cholesterol and other fats. If the diet is high in sugar, triglycerides levels can rise. Tests have shown that when diets high in fat and sugar were supplemented with garlic, the expected rise in blood lipids did not occur.9 Apparently, in some of these tests, aged Garlic extract was the most effective form. Interestingly, in some studies, blood lipids initially rose after taking garlic and then declined. It is believed that because garlic removed fats that were deposited in the tissues into the bloodstream, lipid levels rose temporarily, however, the garlic also helped to metabolize those fats and excrete them from the body.10 Extensive data strongly suggests that garlic is of great value in both the prevention and treatment of cardiovascular disease which is a result of arterial fatty deposits. Using garlic can decrease the phospholipid content of the blood even when the diet is high in saturated fat. This particular action is nothing less than extraordinary. Garlic’s ability to affect a significant reduction in cholesterol appears to be dose-dependent. In other words, the more garlic consumed, the greater the results. Epidemiological studies support this fact and have shown an inverse correlation between cardiovascular disease and garlic consumption in various populations worldwide.11
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=430) What Infections Respond to Echinacea?
Date:
June 24, 2005 01:31 PM
What Infections Respond to Echinacea? Echinacea extracts are excellent when used for various kinds of acute infections. Colds and throat infections seem particularly vulnerable to the immunostimulant action of echinacea. Infections such as influenza and strep are also affected by the herb. Again, taking echinacea on a regular basis does not guarantee that the body will not develop an infection, howe ve r, the duration and seriousness of the infection should be decreased. Antibacterial Action of Echinacea: It is interesting to note that echinacea renders a mild effect on bacteria. It must be remembered, however, that the ability of echinacea to stimulate the immune system may explain its long historical use for bacterial infections. The echinacoside and caffeic acid content of echinacea have been found to inhibit the growth of bacteria such as Staphylococcus aureus, Corynebacterium diphtheria and Proteus vulgaris. 13 Viral Infections and Echinacea : Viral infections are notoriously difficult to treat. Even with all the strides that medical technology has made, finding a cure for viral disease has remained elusive. Echinacea stands out as one of the more effective antiviral herbals. The plant has undergone several studies to determine what exactly makes it an effective virus fighter. Se veral studies have confirmed that when certain laboratory Samples were pre-treated with echinacea compounds, they became protected against exposure to several viruses including: influenza, herpes and vesicular stomatitis (canker sores). Scientists believe that the polysaccharides contained in echinacea called inulin are primarily responsible for the immuno-stimulant effect of this herb. The following listed actions make echinacea especially effective in fighting viral infections and cancero u s conditions.
•. Promotes macrophage activity It is echinacea’s ability to stimulate T-cell activity, that subsequently produces interf e ron which may be responsible for its anti-viral effect. While this theory has been disputed, ingesting certain forms of echinacea has resulted in some degree of protection against viral infection. Fresh echinacea juice appears to be the most effective form of the herb. In any case, research strongly suggests than anyone who consumes echinacea regularly can expect protection against some viral infections to a certain degree. Respiratory System Infections and Echinacea: Echinacea has become well known for its ability to treat respiratory infections including: influenza, tonsillitis, whooping cough, and colds. In addition, bronchial and ear infections respond well to echinacea therapy. The majority of research that supports this action of echinacea was done in Europe with injectable forms of echinacea which are not legal here. Using whole, powd e red, capsulized echinacea on a daily basis during the winter months may also provide significant protection against these respiratory diseases. Concentrated liquid extract is also recommended.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=415) ENDNOTES
Date:
June 23, 2005 11:50 AM
ENDNOTES
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=410) CLINICAL APPLICATIONS OF CAPSICUM
Date:
June 23, 2005 11:20 AM
CLINICAL APPLICATIONS OF CAPSICUM Capsicum is a remarkable whole body stimulant that can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain and fight off infection. One very authoritative work on African plants suggests that Capsicum’s “regular ingestion is highly beneficial in hemorrhoids, varicose veins, anorexia, liver congestion and vascular conditions . . .the indigenous inhabitants of Africa and of the Antilles are remarkably free form all of these conditions as they use Capsicum fruit in their diet.”10 Most of the therapeutic actions of Capsicum are attributed to the alkaloid or glucoside content of the herb.11 The latest scientific studies conducted with Capsicum will be discussed in subsequent sections. Herbal Catalyst Because Capsicum boosts peripheral circulation and stimulates organ secretion, it expedites the therapeutic delivery and action of other herbs. In other words, the medicinal benefits of these herbs reach infected or inflamed tissue more rapidly due to enhanced blood flow.12 Consider the following statement: “Cayenne will insure the rapid and even distribution of the active principles of the rest of the herbs to critical function - al centers of the body, including those involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation. Cayenne is included in several other blends for this reason. In extremely small quantities it can dramatically increase the efficiency of most other herbs.”13 Many health practitioners believe that the key to healing is CAPSICUM stimulation. Capsicum stimulates eve rything from blood flow to peristaltic action in the stomach, to intestinal transit time. The re m a rkable ability of Capsicum to stimulate organ secretion and even heart action makes it one of the strongest natural stimulants known. Se veral different kinds of herbal blends targeting various body systems will utilize Capsicum to boost the formula’s efficacy. Cardiovascular Tonic Capsicum is said to be unequaled for its ability to boost circulation and increase heart action. Interestingly, cultures who consume significant amounts of cayenne pepper in their diet have much lower rates of cardiovascular disease.14 Capsicum exerts a variety of desirable actions on the entire card i ovascular system. It has the extraordinary ability to enhance cardiovascular performance while actually lowering blood pressure.15 A quote taken from a card i ovascular publication re a d s , “Capsaicin has also been shown to prolong cardiac action potential in atrial muscle . . .”16 Michael T. Murray, N.D., has stated, “ Cayenne pepper [Capsicum] should be recommended as a food for its beneficial antioxidant and cardiovascular effects.”17 Herbalists have considered Capsicum as a superior “f o o d” for the heart. In fact, in cases where a heart attack is suspected administering capsicum in hot water has been thought to help lessen the severity of the attack. Capsicum can also be placed on or under the tongue in emergencies involving heart attack, stroke or hemorrhaging. 18 Note: Using Capsicum for any heart-related problem, especially a suspected heart attack should never take the place of medical attention or a physician’s care. CAPSICUM Blood Cholesterol Reducer Various studies have conclusively demonstrated that Capsicum reduces the risk of developing atherosclerosis (hardening of the a rteries) by reducing blood cholesterol and triglyceride levels .19 Additional clinical studies conducted in India found that when cayenne was ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels was significantly inhibited. In addition, bile acids and free cholesterol were subsequently eliminated from the body through the stool.20 Interestingly, these tests revealed that using Capsicum was actually more effective in reducing cholesterol that capsaicin alone.2 1 Daniel Mowrey, Ph.D., emphatically points out that this is just one of many examples of the superiority of whole botanicals as opposed to their isolated components.22 Note: Using Capsicum in combination with Hawthorn is a particularly good cardiovascular tonic. Blood Pressure Equalizer While an added bonus of Capsicum’s capability to lower blood serum cholesterol is a decrease in blood pressure, additional evidence strongly suggests that the herb initiates other mechanisms that fight hypertension .23 “Cayenne, according to another study, also reduces the blood pressure in an even more direct manner: a number of years ago, a team of researchers discove red that capsaicin acts in a reflexive manner to reduce systemic blood pressure, a kind of coronary chemoreflex.”24 Adding Garlic to Capsicum creates an even better therapeutic blend for treating hypertension. Blood Detoxification CAPSICUM “Cayenne is a kind of catalyst in the blood purification process . . . it acts as a diaphoretic, stimulating the excretion of wastes in the swe a t . ”25 Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it would only stand to reason that it would also facilitate the faster removal of toxins from the bloodstream and lymphatic system. You may have already noticed that Capsicum is frequently added to blood-purifying herbal combinations. Circulatory Booster Researchers have found that the simulating action of Capsicum on surface capillaries can help to pre vent cold hands and feet.2 6 For this reason, it may be helpful for Reynaud’s Syndrome. Old remedies using Capsicum have even recommended placing it in socks to warm the feet and to help prevent frostbite. An old folk cure for a chilled body was a steaming hot cup of Capsicum tea. Free Radical Scavenger The rich flavonoid content of Capsicum gives it significant antioxidant capabilities. A recent study conducted in 1995 showed that Capsicum has a higher ascorbic acid content than chiles from the jalapeno or serrano varieties .27 Vitamin C and bioflavonoids can scavenge for dangerous free radicals which cause tissue damage and can predispose organs to degenerative diseases. Free radicals are found everywhere and are created as by-products of metabolic p rocesses including the act of breathing itself. Pollutants can expose the body to free radicals. An interesting study done in Mexico City and published in 1993 found that Capsicum extract was able to modulate the mutagenic activity of urban air Samples.28 In other words, these potentially dangerous nitro - a romatic compounds found in polluted air were kept from mutating by red chile extract.29 Chemical breakdowns of Capsicum have also found that CAPSICUM the pepper is high in Provitamin A, which significantly contributes to its healing ability and immune fortification.30 Anti-Carcinogenic Compound Anti-cancer research recently tested Capsicum on laboratory rats and found that it does indeed demonstrate anti-cancer properties by inhibiting certain enzymes which can initiate the mutation of cells.31 What this implies is that taking Capsicum can afford the body some protection against the cellular mutation which occurs in malignant growths. Capsicum actually inhibited the formation of dangerous metabolites under laboratory conditions where they should have normally been activa t e d .3 2 This study implies that Capsicum may have many more sophisticated bio-chemical actions than previously thought. An Impressive Pain Killer Capsaicin has recently emerged as a remarkably effective pain reliever and has become the subject of recent clinical research . Applying capsaicin in cream or ointment form to painful joints, scar tissue or other painful conditions involving peripheral nerves confuses pain transmitters. In other worlds, capsaicin temporarily disrupts sensory nerve cell biochemistry there by impeding the relay of pain sensations from the skin surface. It does this by inhibiting a neurotransmitter called substance P. This specific compound is thought to be the main mediator of pain impulses from peripheral nerve endings.33 Substance P has also demonstrated its ability to inhibit inflammatory pain generated in arthritic joints in much the same way.34 Today, several over-the-counter topical preparations utilize capsaicin for the pain of arthritic joints. The ability of Capsicum to control severe and unresponsive pain is significant, to say the least. Modern clinical utilization of topical capsaicin may offer signifi-cant relief for a number of painful conditions including: diabetic neuropathy, cluster headaches, post-amputation pain, post-mastectomy pain, shingles and painful scar tissue.35 POST-SURGICAL PAIN In the early spring of 1996, prime time national news show s reported that scientists had found that individuals who had suffered from chronic pain in post-surgical scars (heart bypass, arterial grafts, etc.) were successfully treated with topical preparations containing capsaicin. While this may have been news to many of us, clinical studies had been already published for several years that capsaicin held profound value for various kinds of pain which did not respond to established medical treatments. Typically surgical scars and regions around them can produce persistent pain or can be very sensitive to the touch even when completely healed. This type of pain phenomenon seems to respond well to capsaicin ointments and creams. POST-MASTECTOMY PAIN When capsaicin preparations were applied following mastectomy or breast reconstruction, pain was significantly relieved. Se veral double blind studies found that using capsaicin creams four times daily for 4 to 6 weeks resulted in much less frequent occurrence of sharp, jabbing pain.3 6 All thirteen patients studied had a 50 percent or greater improve m e n t .3 7 Various unpleasant sensations other than pain also improved with topical applications of capsaicin creams.38 MOUTH SORES FROM RADIATION OR CHEMOTHERAPY A fascinating study conducted at the Yale Pain Management Center discove red that capsaicin could ve ry significantly lessen pain caused by mouth sores which frequently develop after chemotherapy or radiation.39 Apparently delivering the capsaicin in the form of soft candy (taffy) enabled the substance to be retained in the mouth long enough to desensitize the nerve endings causing the pain. Each one of the eleven case studies re p o rted that their pain had decreased and in two patients, it stopped entirely.40 DIABETIC NEUROPATHY Diabetic neuropathy is a painful nerve condition which can develop in cases of prolonged diabetes. Several double-blind studies have supported the considerable value of capsaicin creams for relieving the pain associated with this disorder.41 The results of a controlled study using Capsicum for seve re cases of diabetic neuropathy which did not respond to conventional therapy were published in 1992. A cream containing Capsicum was applied to painful areas four time a day and pain was carefully e valuated for 8 weeks at two-week intervals. The results we re impressive, to say the least. In the 22 patients who used the Capsicum the following results we re re c o rded: “Capsaicin tre a tment was more beneficial than vehicle treatment in the overall clinical improvement of pain status, as measured by physician’s global evaluation and by a categorical pain severity scale . . . In a follow-up study, approximately 50 percent of the subjects reported improved pain control or were cured . . .”42 No t e : While there was a burning sensation when the Capsicum c ream was first applied, some subjects found that its magnitude and duration lessened with continued application.43 SHINGLES The FDA has approved capsaicin-based ointments for the treatment of pain that results from diseases like shingles. Again, numerous studies have documented the value of capsaicin for decreasing the miserable nerve-related pain associated with shingles. The general consensus derived from these tests were that approximately 50 p e rcent of people suffering from shingles responded well to capsaicin creams, some even after 10 to 12 months.44 Note: If blisters accompany a shingles outbreak, it is better to wait until they have healed before using any capsaicin-based ointments or creams. RELIEF FOR BURNING FEET Frequently an uncomfortable “burning” sensation in the feet will occur in many people, particularly in diabetics. As ironic as it may seem, using capsaicin creams may actually alleviate this burning. “In various studies, diabetics who treated their burning feet with capsaicin got greater improvement and we re able to walk more easily than those not using the cream.”45 In addition, using topical applications of capsaicin as opposed to strong, oral drugs is much more preferable. ARTHRITIS PAIN Clinical tests have confirmed that topical capsaicin ointments substantially alleviate the miserable pain that characterizes osteoand rheumatoid arthritis.46 These studies revealed that using 0.075 capsaicin cream reduced tenderness and pain.47 Dr. Michael T. Murray writes: “ . . . seventy patients with osteoarthritis and thirty - one with rheumatoid arthritis received capsaicin or placebo for 4 weeks. The patients were instructed to apply 0.025 percent capsaicin cream or its placebo to painful knees four times daily. Significantly more relief of pain was reported by the capsaicin-treated patients than by the placebo patients throughout the study . . .”48 Anyone suffering from osteo or rheumatoid arthritis should evaluate the effectiveness of capsaicin ointments for joint pain. Ester Lipstein-Kresch, M.D., has studied the effectiveness of capsaicin creams for arthritis and has stated: “You need to apply it three or four times a day on the affected area for at least two weeks before you’ll see any improvement. An initial burning sensation at the site is not unusual for the first few days, but this goes away with continued application.”49 Note: Capsaicin is also useful for tennis elbow due to its ability to block the transmission of pain. MIGRAINE HEADACHES (CLUSTER TYPE) Topical applications of capsaicin ointments intranasally may also help to relieve the pain of a specific kind of migraine headache called cluster headaches. Cluster headaches are characterized by s e ve re pain which typically radiates around one eye. The term “cluster” refers to the fact that these headaches tend to occur in clusters of one to three per day and can recur at intervals. Headache pain and severity we re reducing in groups using intranasal capsaicin.5 0 This type of capsaicin treatment should be done under a physician’s care. There is some speculation that capsaicin may be more effective in pre venting migraines before they develop into a full blown attack.51
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=405) Sytrinol - A Natural Solution for Addressing Cholesterol
Date:
June 21, 2005 05:16 PM
Sytrinol - A Natural Solution For Addressing Cholesterol By Richard F. Staack, Ph.D., M.B.A. Sytrinol™, a patented proprietary formula derived from natural citrus and palm fruit extracts, combines citrus polymethoxylated flavones (PMFs), palm tocotrienols and other proprietary constituents. This combination results in a synergistic effect for maintaining cholesterol levels in the normal range, including total cholesterol, LDL cholesterol, and triglyceride levels, as demonstrated by a long-term, three-phase clinical trial. This trial is extremely significant because it is a randomized, placebo-controlled, crossover design, one of only a few in the dietary supplement industry. Sytrinol has also been shown to maintain normal levels of high-density lipoproteins (HDL), the beneficial cholesterol. Additionally, Sytrinol is a powerful antioxidant with numerous heart health benefits and also plays a significant role in reducing cellular irritation. What are polymethoxylated flavones? Polymethoxylated flavones are a highly methoxylated sub-classification of citrus flavonoids. This process occurs naturally and results in a more biologically active molecule. This is especially true for tangeretin and nobiletin, two of the primary polymethoxylated flavones in Sytrinol. Tocotrienols, naturally occurring analogues of tocopherol (natural vitamin E), are the other proprietary ingredient in Sytrinol and are a group of minor dietary constituents that have been studied for their effect on heart health. Sytrinol's Proven Benefits Sytrinol is the result of over 12 years of research focusing on the relationship between polymethoxylated flavonoids, tocotrienols, and cardiovascular health. Sytrinol?s benefits have been shown in vitro, in vivo, and in multiple clinical studies. In these studies, subjects consumed 150 mg of Sytrinol twice per day (300 mg/day) and were instructed to keep the same dietary habits and maintain their caloric intake. Fasting blood Samples were drawn at study onset, and at 4-weeks, 8-weeks, and 12-weeks. The results of the clinical studies were all similar in their effect, with a reduction of total cholesterol up to 30 percent, LDL cholesterol up to 27 percent, and total triglycerides up to 34 percent in twelve weeks compared to the placebo group. Additionally, the LDL/HDL ratio was significantly reduced in all clinical studies up to 30 percent. Another very important benefit of Sytrinol that cannot be claimed by other cholesterol-addressing supplements is its effect on C-reactive protein (CRP), which plays a role in cardiovascular challenges. Recent research has established that inflammation may cause C-reactive protein to be produced in the body. Specific PMFs, including nobiletin and tangeretin, have been studied for their anti-inflammatory properties, suggesting that Sytrinol may have a positive effect on CRP Sytrinol has also been shown to be a powerful antioxidant. The polymethoxylated flavones have been researched for over 25 years demonstrating their antioxidant effects for heart health. Studies have shown that polymethoxylated flavonoids and their metabolites are excellent sources of dietary antioxidants that are able to suppress many of the events of free radical damage, including cellular irritation. The tocotrienols in Sytrinol have a higher antioxidant activity than tocopherols. Alpha-tocotrienol has been shown to be up to 60 times more potent than alpha-tocopherol in the prevention of lipid peroxidation. Other research has demonstrated that the delta and gamma isomers of tocotrienols also have potent antioxidant activity. Mechanisms Sytrinol has three complementary mechanisms of action in the body that delivers cardiovascular benefits. *Polymethoxylated flavones decrease apolipoprotein B, the structural protein needed for endogenous synthesis of LDL cholesterol. *Polymethoxylated flavones (tangeretin & nobiletin) decrease diacylglycerol acetyl transferase, a liver enzyme needed for endogenous synthesis of triglycerides. *Tocotrienols inhibit HMG CoA reductase, the liver enzyme responsible for endogenous synthesis of cholesterol. These mechanisms work synergistically to support normal total cholesterol, LDL cholesterol, and triglyceride levels, more significantly than other natural supplements on the market today. Sytrinol can also be combined with other ingredients such as phytosterols. Phytosterols help block cholesterol in the gastrointestinal tract while Sytrinol helps block cholesterol synthesis in the body. This suggests that, when combined, a more pronounced effect on maintaining normal cholesterol levels would result. Consumer Friendly The ease of compliance for consumers is a major consideration for a successful natural heart health product. Consumers do not have to take Sytrinol prior to, immediately following, or directly with their meals and, as a result, are more likely to take the correct dosage and continue using the product. Sytrinol can be taken in tablets, or softgels, which are easy to swallow because of the low dosage. Sytrinol will also be available in functional foods.
Dr. Richard Staack is the Vice President of Business Development, Technology, and Science at SourceOne™ Global Partners. He received his Master of Science and Doctorate in Nutritional and Biochemical Toxicology from the University of Illinois, Urbana-Champaign. He received his Master of Business Administration with Distinction from DeVry University. Dr. Staack has received several awards and honors in the field of nutrition, is associated with numerous professional affiliations, and has published several articles on nutrition and toxicology in peer-reviewed journals.
Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=386) Modified Citrus Pectin (MCP) and Mercury Cleansing Programs...
Date:
June 21, 2005 05:02 PM
Modified Citrus Pectin (MCP) and Mercury Cleansing Programs by Isaac Eliaz, M.D., M.S., L.Ac. Modified Citrus Pectin (MCP) is a dietary supplement derived from the peel and pulp of citrus fruit. MCP is mostly known for its positive effects on cellular health. Recently, however, clinical research on MCP has produced exciting results for its use as a gentle chelator (eliminator) of mercury and other heavy metals. Some of the expanding clinical applications for MCP include: The Problem with Mercury Recent news on mercury is particularly concerning for the U.S. population. In March 2004 the EPA issued a press release reporting nearly all fish contained traces of mercury. Some Samples contained levels high enough to harm an unborn baby or young child's developing nervous system. These findings prompted the EPA to issue a warning to women who may become pregnant, pregnant women and nursing mothers advising them to eat only two meals of fish per week that are thought to have lower levels of mercury.1 In their most recent update (August 2004), the EPA issued a warning that 1/3 of the nation's lakes and 1/4 of its river ways are contaminated with toxic levels of mercury and other contaminants, and warned pregnant women and children against consumption of fish from these sources. Additionally, a National Academy of Sciences panel definitively warned that some children who had been exposed to mercury while in the wombs of their mothers were at risk for becoming those children "who have to struggle to keep up in school and who might require remedial classes of special education." The risk of mercury toxicity from fish has reached epidemic levels. Two studies have further spurred on the concerns of mercury toxicity, as they both found women to have mercury levels that are 8-10% above what is considered safe.1,2 Furthermore, women who ate more fish were found to have higher levels of mercury. Another source of mercury toxicity may be amalgam dental fillings. Heavy metals, in conjunction with the abundant presence of environmental toxins and xenoestrogens, constitute a dangerous insult to the body through DNA damage, hormonal modulation, immune suppression, oxidative stress, and cellular irritation. A New Application for MCP Use: Heavy Metal Detoxification The standard western medical approach for removing mercury from the body to treat mercury toxicity is chelation. This procedure is performed with harsh chelators that can cause multiple side effects while potentially robbing the body of some of its essential nutrients. While this may be the routine and most beneficial procedure when facing a serious toxicity problem, are there other, gentler ways to reduce mercury levels? Two recent clinical studies have found that MCP may be a promising new dietary solution for reducing heavy metal load. In one recent clinical study, MCP was administered to a group of volunteers, and baseline levels of their total body mercury burden were measured and then compared against levels after treatment with MCP (15 grams of PectaSol® daily) for four months. The results showed a significant average decrease (over 60%; p=0.03) in the total body mercury burden after treatment with MCP3 In an earlier study, PectaSol® was given to patients and proven to increase urinary secretion of heavy metals such as lead, mercury, cadmium and arsenic.4 Both studies concluded that MCP may be a promising alternative to the harsher intravenous chelating therapies as MCP was found to be both effective and free of any side effects. How MCP Works as a Gentle Chelator Pectins are natural gelling agents, binders, thickeners, and stabilizers in foods. They mostly consist of galacturonic acid and galacturonic-acid methyl esters with average molecular weights from 50,000 to 150,000 daltons. High-methoxy (HM) pectin has at least 50% DE (degree of esterification) or greater, while a low-methoxy (LM) pectin?s DE is 50% or less. For systemic chelation of heavy metals, pectin is modified to a low molecular weight, and low-methoxy content. My observation from using MCP as a detoxification agent in my clinic is that it works as a gentle chelator in the bloodstream and it is very useful for ongoing use. Because fish are still recommended as part of a healthy diet and an essential source of certain nutrients (essential fatty acids like DHA), mercury levels are also becoming a widespread health concern. It is a Catch-22 for dietary health. As the widespread environmental cleanup of mercury is unlikely in the short-term, the medical community should develop methods to treat toxicity or reduce high body levels of mercury body burden. One approach is the use of traditional and alternative medicine cleansing programs along with the use of dietary supplements such as MCP that may act as gentle chelators. For chelation purposes, 5-15 grams of MCP should be taken per day depending on mercury levels for one year. Maintenance at 2-5 grams per day thereafter is usually sufficient. In my practice, I use 15 grams per day or 15 grams per day in the first 3-5 days of the month and 5 grams per day for the remainder of the month. MCP is generally regarded as safe and is well tolerated. Reported side effects have been rare, but may include mild and transient gastrointestinal discomfort. References: 1-CDC Press Release: Blood and Hair Mercury Levels in Young Children and Women of Childbearing Age-United States, 1999 (see:/media/mmwrnews/n010302.htm#mmwr3) 2-Schober, SE, Sinks, TH, Jones, RL et al. (2003) Blood mercury levels in US children and women of childbearing age, 1999-2000. Journal of the American Medical Association. 289(13) :1667-74. 3-Eliaz, I. (2004) Modified citrus pectin (MCP) in the treatment of cancer. Paper presented at: The American Chemical Society Annual Meeting; Philadelphia, PA. 4-Eliaz, I. and D. Rode (2003). The effect of modified citrus pectin on the urinary excretion of toxic elements. Fifth Annual Conference of Environmental Health Scientists: Nutritional Toxicology and Metabolomics, University of California, Davis.
-------------------------------------------------------------------------------- Isaac Eliaz, M.D., M.S., L.Ac., is a pioneer in the field of integrative medicine and founder of Better Health Publishing®, an education-based company that provides health care professionals, consumers and other interested parties with scientific research on integrative medicine. He is a respected author, clinical practitioner and frequent guest lecturer on integrative medical approaches to health, immune enhancement and cancer prevention and treatment. Since 1991, Dr. Eliaz has maintained a busy private practice in Sebastopol, California, and is the current medical director of the Amitabha Medical Clinic and Healing Center (email:information@amitabhaclinic.com) which focuses primarily on integrative and holistic protocols for cancer patients as well as those with chronic health challenges.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=382) Prosta Response - Supports Prostate Function and Healthy Urine Flow
Date:
June 04, 2005 01:56 PM
Bookstores are filled with it, news magazines are reporting on it. From the revelations of politicians to disturbing statistical reports, prostate health issues that formerly received little notice are now in the headlines. The prostate is a walnut-sized gland located under the bladder and surrounding the urinary tract in men. Many factors affect prostate wellness, including aging and individual genetic history, but today’s chemicalized environment poses unprecedented challenges to the health of the prostate gland. Source Naturals is helping to meet this challenge with PROSTA-RESPONSE, a Bio-Aligned Formula™ designed to support multiple, interdependent body systems. It is the only prostate formula that addresses six body systems involved with healthy prostate function. More than Symptoms*, Systems PROSTA-RESPONSE is a unique formula that combines clinically tested potencies of saw palmetto extract and beta sitosterol with standardized Swedish flower pollen extract, quercetin, lyopene, soy and additional herbs and nutrients. PROSTA-RESPONSE goes beyond formulas that simply address nutritional symptoms and instead deals with underlying causes. PROSTARESPONSE supports healthy prostate function and urine flow by addressing the following body systems: 1. Hormone regulation: Hormones have a direct role in prostate functioning and have been closely linked to prostate health. PROSTA-RESPONSE contains specific plant extracts and nutrients shown in research to inhibit the conversion of testosterone to dihydrotestosterone (DHT), and the subsequent binding to receptors within the prostate. 2. Prostate cell regeneration: Swedish flower pollen extract, used extensively in Europe and Asia for more than 40 years, has demonstrated significant effects in maintaining proper prostate cell regeneration. 3. Soothing mechanisms: Certain plant compounds, such as flavonoids from soy and sterols from pollen extract, inhibit the metabolism of arachidonic acid. This in turn influences prostaglandin synthesis, which may be associated with comfort levels. 4. Bladder and urinary tract health: A healthy environment within the bladder and urinary tract is vital for prostate health and normal urine flow. PROSTARESPONSE contains botanicals that support the bladder and urinary tract health. 5. Prostate health: Studies show that dietary factors influence the overall health of the prostate. The body naturally concentrates certain compounds in higher amounts in the prostate. These include zinc, vitamin E and soy isoflavones. 6. Antioxidant defense: Antioxidants play an important role in maintaining prostate function and cell membrane integrity. Oxidative stress, or the action of free radicals, is confirmed as a significant factor that can trigger a host of destructive processes. Developing a Prostate-Friendly Lifestyle Supplementation is only one part of an individual’s Strategy for WellnessSM. That’s why Source Naturals® is committed to providing public education about the many aspects of a prostate-healthy lifestyle. Less Fat, More Fiber, Lots of Veggies Studies suggest a direct relationship between dietary fat and prostate health, with men whose diets consist of 30%-40% or more fat at highest risk. Saturated fats, especially from animal sources, are most problematic. Some research has attributed this relationship to the effect animal fats have on excess levels of circulating sex hormones. Prostate health is also associated with high fiber intake. This may be because dietary fiber binds testosterone, estradiol and other sex steroids and helps eliminate excess hormones, Five to nine servings of high-fiber fruits, vegetables, beans and whole grains (35 g) are recommended daily for prostate health. Tomato-based foods are rich in the carotenoid, lycopene, which is a potent antioxidant, helping to protect our cells and fatty tissues from free radical damage. A long-term study at Harvard School of Medicine found beneficial effects from 10 servings of tomato products weekly, while recent clinical research points to an intake of 15 mg of lycopene twice per day. Also helpful are green and yellow-orange vegetables, which contain compounds that are converted to vitamin A; citrus fruits that contain vitamin C; nuts and seeds that contain vitamin E; zinc-containing seafood, legumes and eggs; and selenium-rich whole grains, seafood and organ meats. Studies show a correlation between prostate health and diets that contain large amounts of soy. Soybeans contain prostate-healthy phytoestrogens, including the isoflavone, genistein. Some experts suggest eating seven servings of soy protein per week (providing 10 g of soy protein and 20 mg of isoflavones daily) for general good health, and three times that amount for more targeted protection. Drink Healthy Dehydration stresses the prostate gland. It is important to consume plenty of water—about eight glasses per day. Plain water is best, but you can also drink highly diluted fruit juice, herbal tea or lightly flavored sparkling water. Green tea is beneficial for prostate health, due to certain antioxidant compounds called polyphenols. You can reduce the frequency of nighttime trips to the bathroom by eliminating fluids a few hours before you go to sleep. You may find it more comfortable to spread out your intake, taking small sips of fluids over the course of the day. Exercise Good circulation is important for prostate health. Regular walking is excellent in this regard. “Kegel” exercises— a series of contractions of the muscles around the prostate—are helpful for improving circulation and tonicity of the genital area. Supplementation Supplementation tailored to prostate wellness would focus on the vitamins and minerals described above—in addition to nourishing our body systems, many are also antioxidants, helping to counter the free radical damage that is rampant in our chemicalized environment. The program would also include specific herbs found to support prostate function, especially saw palmetto, pygeum, and pumpkin seeds. First Bio-Aligned Formula for the Prostate Gland! PROSTA-RESPONSE is the first prostate support formula designed to work holistically, by addressing the multiple systems that affect prostate higher amounts in the prostate. health. Try Source Naturals PROSTA-RESPONSE, available in bottles of 45 and 90 tablets. PROSTA-RESPONSE™: A Bio-Aligned Formula™ Multi-System Support for the Prostate Gland Hormonal Regulation: Nettle, Pygeum, Red Clover, Saw Palmetto, Soy, Swedish Flower Pollen Extract, Zinc, Vitamin D-3 Prostate Cellular Regeneration: Lycopene, Nettle, Quercetin, Red Clover, Swedish Flower Pollen Extract, Vitamin D-3 Soothing Mechanisms: Prostaglandin Synthesis Beta Sitosterol, Pygeum, Quercetin, Red Clover Saw Palmetto, Soy, Swedish Flower Pollen Extract Bladder & Urinary Tract Health: Alanine, Glutamic Acid, Glycine, Goldenseal, Gravel Root, Marshmallow Root, Pumpkin Seed, Pygeum, Swedish Flower Pollen Extract, Uva Ursi Prostate Health: Red Clover, Soy, Zinc, Vitamin E Antioxidant Defense: Ginkgo Biloba, Grape Seed, Green Tea, Lycopene, Pygeum, Quercetin, Red Clover, Soy, Swedish Flower Pollen Extract, Selenium, Zinc, Vitamin E
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=187) Prosta Response - 45ct, 90ct, and 180ct --
Date:
May 20, 2005 07:36 PM
ookstores are filled with it, news magazines are reporting on it. From the revelations of politicians to disturbing statistical reports, prostate health issues that formerly received little notice are now in the headlines. The prostate is a walnut-sized gland located under the bladder and surrounding the urinary tract in men. Many factors affect prostate wellness, including aging and individual genetic history, but today’s chemicalized environment poses unprecedented challenges to the health of the prostate gland. Source Naturals is helping to meet this challenge with PRO STA RESPONSE, a Bio-Aligned Formula™ designed to support multiple, interdependent body systems. It is the only prostate formula that addresses six body systems involved with healthy prostate function. More than Symptoms*, Systems PRO STA-RE SPONSE is a unique formula that combines clinically tested potencies of saw palmetto extract and beta sitosterol with standardized Swedish flower pollen extract, quercetin, lyopene, soy and additional herbs and nutrients. PRO-STA- RESPONSE goes beyond formulas that simply address nutritional symptoms and instead deals with underlying causes. PROSTARESPONSE supports healthy prostate function and urine flow by addressing the following body systems: 1. Hormone regulation: Hormones have a direct role in prostate functioning and have been closely linked to prostate health. PRO STA RESP ONSE contains specific plant extracts and nutrients shown in research to inhibit the conversion of testosterone to dihydrotestosterone (DHT), and the subsequent binding to receptors within the prostate. 2. Prostate cell regeneration: Swedish flower pollen extract, used extensively in Europe and Asia for more than 40 years, has demonstrated significant effects in maintaining proper prostate cell regeneration. 3. Soothing mechanisms: Certain plant compounds, such as flavonoids from soy and sterols from pollen extract, inhibit the metabolism of arachidonic acid. This in turn influences prostaglandin synthesis, which may be associated with comfort levels. 4. Bladder and urinary tract health: A healthy environment within the bladder and urinary tract is vital for prostate health and normal urine flow. PROSTARESPONSE contains botanicals that support the bladder and urinary tract health. 5. Prostate health: Studies show that dietary factors influence the overall health of the prostate. The body naturally concentrates certain compounds in higher amounts in the prostate. These include zinc, vitamin E and soy isoflavones. 6. Antioxidant defense: Antioxidants play an important role in maintaining prostate function and cell membrane integrity. Oxidative stress, or the action of free radicals, is confirmed as a significant factor that can trigger a host of destructive processes. Developing a Prostate-Friendly Lifestyle Supplementation is only one part of an individual’s Strategy for WellnessSM. That’s why Source Naturals® is committed to providing public education about the many aspects of a prostate-healthy lifestyle. Less Fat, More Fiber, Lots of Veggies Studies suggest a direct relationship between dietary fat and prostate health, with men whose diets consist of 30%-40% or more fat at highest risk. Saturated fats, especially from animal sources, are most problematic. Some research has attributed this relationship to the effect animal fats have on excess levels of circulating sex hormones. Prostate health is also associated with high fiber intake. This may be because dietary fiber binds testosterone, estradiol and other sex steroids and helps eliminate excess hormones, Five to nine servings of high-fiber fruits, vegetables, beans and whole grains (35 g) are recommended daily for prostate health. Tomato-based foods are rich in the carotenoid, lycopene, which is a potent antioxidant, helping to protect our cells and fatty tissues from free radical damage. A long-term study at Harvard School of Medicine found beneficial effects from 10 servings of tomato products weekly, while recent clinical research points to an intake of 15 mg of lycopene twice per day. Also helpful are green and yellow-orange vegetables, which contain compounds that are converted to vitamin A; citrus fruits that contain vitamin C; nuts and seeds that contain vitamin E; zinc-containing seafood, legumes and eggs; and selenium-rich whole grains, seafood and organ meats. Studies show a correlation between prostate health and diets that contain large amounts of soy. Soybeans contain prostate-healthy phytoestrogens, including the isoflavone, genistein. Some experts suggest eating seven servings of soy protein per week (providing 10 g of soy protein and 20 mg of isoflavones daily) for general good health, and three times that amount for more targeted protection. Drink Healthy Dehydration stresses the prostate gland. It is important to consume plenty of water—about eight glasses per day. Plain water is best, but you can also drink highly diluted fruit juice, herbal tea or lightly flavored sparkling water. Green tea is beneficial for prostate health, due to certain antioxidant compounds called polyphenols. You can reduce the frequency of nighttime trips to the bathroom by eliminating fluids a few hours before you go to sleep. You may find it more comfortable to spread out your intake, taking small sips of fluids over the course of the day. Exercise Good circulation is important for prostate health. Regular walking is excellent in this regard. “Kegel” exercises— a series of contractions of the muscles around the prostate—are helpful for improving circulation and tonicity of the genital area. Supplementation Supplementation tailored to prostate wellness would focus on the vitamins and minerals described above—in addition to nourishing our body systems, many are also antioxidants, helping to counter the free radical damage that is rampant in our chemicalized environment. The program would also include specific herbs found to support prostate function, especially saw palmetto, pygeum, and pumpkin seeds. First Bio-Aligned Formula for the Prostate Gland! PROSTA-RESPONSE is the first prostate support formula designed to work holistically, by addressing the multiple systems that affect prostate higher amounts in the prostate. health. Try Source Naturals PRO STA-RE SPONSE, available in bottles of 45 and 90 tablets. Hormonal Regulation Freeze Dried stinging Nettle, Pygeum, Red Clover, Saw Palmetto, Soy, Swedish Flower Pollen Extract, Zinc, Vitamin D-3 Prostate Cellular Regeneration Lycopene, Nettle, Quercetin, Red Clover, Swedish Flower Pollen Extract, Vitamin D-3 Soothing Mechanisms: Prostaglandin Synthesis Beta Sitosterol, Pygeum, Quercetin, Red Clover Saw Palmetto, Soy, Swedish Flower Pollen Extract Bladder & Urinary Tract Health Alanine, Glutamic Acid, Glycine, Goldenseal, Gravel Root, Marshmallow Root, Pumpkin Seed, Pygeum, Swedish Flower Pollen Extract, Uva Ursi Prostate Health Red Clover, Soy, Zinc, Vitamin E Antioxidant Defense Ginkgo Biloba, Grape Seed, Green Tea, Lycopene, Pygeum, Quercetin, Red Clover, Soy, Swedish Flower Pollen Extract, Selenium, Zinc, Vitamin E PROSTA-RESPONSE™: A Bio-Aligned Formula™ Multi-System Support for the Prostate Gland References Buck, A.C. 1996. Phytotherapy for the prostate. Brit J Urol 78:325-336. Morton, M.S. et al. Lignans and isoflavonoids in plasma and prostatic fluid in men: Samples from Portugal, Hong Kong, and the United Kingdom. Prostate 32:122-128. Morton, M.S. et al. 1996. The preventative role of diet in prostatic…Brit J Urol 77:481-493. Wilt, T.J. et al. 1998. Saw palmetto extracts…a systematic review. JAMA 280:1604-1609 Yasumoto, M.D. et al. Jan-Feb 1995. Clinical evaluation of long-term treatment using …pollen extract…Clin Ther 17(1):82-87. *The term symptom as used in this literature refers to the effects of nutrient imbalances and shortages, and is not related to the diagnosis, treatment, cure, or prevention of any disease.
Prosta Response 45ctProsta Response 90ctProsta Response 180ct-- VitaNet® VitaNet ® Staff
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=85) Guggul – New Benefits for Heart Health 
Date:
May 11, 2005 09:00 PM
Gum Guggul–New Benefits for Heart Health from an Age-Old Herbby Richard Conant, L.Ac., C.N.The 1990's have seen a growing interest in herbs from India's ancient Ayurvedic tradition. One Ayurvedic herb in particular, "gum guggul," stands at the forefront, thanks to its rather remarkable benefits for the heart and cardiovascular health. A relative of myrrh and frankincense, gum guggul is a resin tapped from India's Commiphora mukul tree. Known more commonly in the Far East as simply "guggul," the herb has proven to be one of the most effective natural cholesterol-lowering agents ever discovered. Cholesterol reductions with guggul can be twenty percent or higher, and the herb also raises HDL, the more beneficial form of cholesterol. Studies also show guggul may help prevent atherosclerosis, by retarding the formation of fatty, cholesterol-laden deposits in blood vessel tissues. Recent research on guggul has revealed that guggul also blocks the oxidation of LDL cholesterol, by acting as an antioxidant. LDL, which carries cholesterol from the liver to the rest of the body, is generally regarded as a key element in the development of atherosclerosis. But only when it is oxidized by free radicals does LDL accumulate in arteries. It its unoxidized or "native" state, LDL is more or less benign. Checking LDL oxidation is vital to keeping blood vessels free of plaque.1 (This is one of the major reasons why antioxidants are so important.) Guggul, by both lowering blood cholesterol and acting against LDL oxidation, now stands out as one of the world's most valuable herbs for heart health. Guggul first caught the attention of the scientific world in1966, thanks to an Indian medical researcher who submitted a doctoral thesis on gum guggul.2 Her interest had been kindled by references to the herb in a centuries-old Ayurvedic text. Apparently, poor cardiovascular health and atherosclerosis were a problem back then just as they are today. Translated from Sanskrit, this text describes, in elegant detail, a condition called "coating and obstruction of channels." The cause, according to the ancient writers? Faulty metabolism due to overeating of fatty foods and lack of exercise. Death was said to be the end result of leaving this condition uncorrected. The recommended treatment plan emphasized diet and herbs, chiefly gum guggul.3 References to guggul in ancient literature actually go back even farther. The herb is mentioned in the Vedas, the holy scriptures of India believed to be anywhere from 3,000 to 10,000 years old. One stanza is translated as follows: "Disease (consumption) does not afflict and the curse never affects whom the delicious odor of the healing Guggul penetrates (spreads). The diseases also flee away in all directions from him like horses and deer, O Gugulu! Either born from Sindhu or from the sea. I chant your name for the removal of diseases."3 Struck by the obvious similarity between "coating and obstruction of channels" and atherosclerosis, the Indian researcher decided to study gum guggul's effect on blood fats in rabbits. Over a two-year period, the animals were fed hydrogenated vegetable oil to artificially raise their cholesterol levels. Guggul was administered to one group of rabbits, while the rest served as controls. At the end of the study the rabbits given guggul had normal cholesterol and blood lipid levels. Their arteries showed no fatty streaks or plague deposits. This caught the attention of the Indian scientific community, and numerous clinical trials ensued, both on animals and humans. In study after study, guggul consistently produced substantial reductions in cholesterol and triglyceride levels, while raising HDL. The active ingredients in guggul are a group of natural plant sterols. Among these, substances called "guggulsterones" are the most important ingredients for the cholesterol and blood fat lowering properties of guggul, with the other sterols acting as a synergistic supporting cast.4 A number of mechanisms are suggested, although not definitely proven, for how the herb works; these include reducing the synthesis of cholesterol in the liver, enhancing cholesterol removal from the gut, stimulating thyroid function and increasing the number of receptors in the liver for uptake of LDL.3,5 Guggul extracts are now standardized for guggulsterone content. The herb naturally contains about 2 percent guggulsterones. Quality extracts contain a minimum of 2.5 percent, which assures the user is getting a product potent enough to produce results. Since the late 1980's clinical trials have used the standardized extract.6,7,8 The product is readily available in the U.S. The ability of guggulsterones to prevent oxidation of LDL was discovered in a 1997 study done by scientists at the Central Drug Research Institute in Lucknow, India.9 This study sheds light on how guggul works against "coating and obstruction of channels." Remember that oxidized LDL forms the plaque that coats and eventually obstructs blood vessels. The researchers mixed LDL from human blood with a free radical promoting agent, either alone or in combination with guggulsterones. Samples were then analyzed for the presence LDL oxidation byproducts. The results showed that guggulsterones strongly protect LDL from being oxidized. Guggulsterones block the formation of hydroxyl radicals, a potent type of free-radical that attacks cell membranes. Guggulsterones may also help keep the heart muscle itself healthy. When the heart muscle is deprived of oxygen, a condition known as "myocardial ischemia," it can be severely damaged by free radicals. The body tries to counter this with SOD, a key enzyme present in cells that neutralizes free radicals. SOD levels are significantly reduced in damaged heart tissues. Guggulsterones have been found to reverse this decrease by more than two-fold.10 Like the writer of that age-old verse found in the Vedas, contemporary herbalists hold gum guggul in the highest regard. Backed as it is by scientific research linked to centuries of traditional use, gum guggul has a bright future as a natural resource for maintaining normal cholesterol and blood fats, and for protecting heart health. References 1. Heinecke, J.W. Free radical modification of low density lipoprotein: mechanisms and biological consequences. Free Radical Biology & Medicine 1987;3:65-73. 2. Satyavati, G.V. Effect of an indigenous drug on disorders of lipid metabolism with special reference to atherosclerosis and obesity (Medoroga) M.D. thesis (Doctor of Ayurvedic Medicine). Banaras Hindu University, varanasi, 1966. 3. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82. 4. Dev, S. A modern look at an age-old Ayurvedic drug-guggulu. Science Age July 1987:13-18. 5. Singh, V. et. al. Stimulation of low density lipoprotein receptor activity in liver membrane of guggulsterone treated rats. Pharmacological Research 1990;22(1):37-44. 6. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28. 7. Agarwal, R.C. et. al. Clinical trial of gugulipid-a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34. 8. 'Gugulipid' Drugs of the Future 1988;13(7):618-619. 9. Singh, K., Chandler, R. Kapoor, N.K. Guggulsterone, a potent hypolipidaemic, prevents oxidation of low density lipoprotein. Phytotherapy Research 1997;11:291-94. 10. Kaul, S. Kapoor, N.K. Reversal of chnages of lipid peroxide, xanthine oxidase and superoxide dismutase by cardio-protective drugs in isoproterenol induced myocardial necrosis in rats. Indian Journal of Experimental Biology 1989;27:625-627.
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Healthful supplements
