Search Term: " anicancer "
Curcumin and Grapeseed
September 01, 2020 11:03 AM
Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society.
Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone.
Two top suggested natural medicines available right now are curcumin and grape seed extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and grape seed extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous.
Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation.
Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells.
Curcumin Must Be Absorbed To Be Useful
One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil.
Curcumin Makes Chemo More Effective
There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells.
Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news!
Curcumin Protects The Body During Cancer Treatment
In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective.
The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement.
At the end of the treatment which lasted 20 weeks the most dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.
Study: Curcumin, a polyphenol in turmeric, can selectively targetcancer stem cells
May 02, 2019 11:57 AM
According to a study published in the journal Anticancer Research, curcumin can destroy stem cells that cause cancer. Turmeric is a plant that has been used in traditional Asian medicine to treat a variety of conditions. Curcumin, a polyphenol found in turmeric, is the source of turmeric's health benefits. Recent research suggests that curcumin can selectively target and destroy cancer stem cells. Cancer stem cells, which are resistant to chemotherapy and radiation, and can actually be spread by surgery, are the most lethal type of cancer cell.
"One of the most well-known of these amazing foods is curcumin, the polyphenol that gives turmeric its beautiful, bright yellow color."
Read more: https://www.naturalnews.com/2019-03-14-curcumin-polyphenol-in-turmeric-can-selectively-target-cancer-stem-cells.html
Go nuts with the cancer-protective properties of walnuts
April 29, 2019 02:48 PM
Despite some of the negative press that the nut group receives overall, there is some significant proof that incorporating nuts, specifically walnuts into your diet can have positive effects. From assisting with cancer prevention, boosting your mood, weight loss assistance and even strengthen your bones, the benefits could outweigh your negative mindset. Also be aware that the method in which you prepare your walnuts could also change the properties of the un-roasted nut structure. Remaining natural with your nut selection is usually best.
"These results, which were published in the journal Nutrition Research, indicated that walnuts reduce the risk of colon cancer by inducing expression of genes involved in detoxification and by causing growth inhibition and apoptosis in colon adenoma cells."
Read more: https://www.naturalnews.com/2019-03-14-go-nuts-with-the-cancer-protective-properties-of-walnuts.html
Discover how a special kind of pine bark improves heart health byreducing the risk of metabolic syndrome
April 24, 2019 03:57 PM
With more and more consideration placed on ways to make you more healthy and physically well, there has been an increase in the holistic forms and natural remedies that have been implemented. In doing so, one interesting trend that is recently being discovered is that of pine bark, a more specific type, that is seen for heart health. By using this pine bark in different foods, it can decrease the risk of metabolic syndrome in individuals.
"Disease-fighting OPCs in pine bark are not only antioxidant (helping to scavenge dangerous free radicals), but have anti-inflammatory, anticancer, anti-allergenic, antibacterial and anti-aging effects as well."
Read more: https://www.naturalhealth365.com/pine-bark-heart-health-2823.html
Why melatonin is a powerful anticancer indolamine
April 19, 2019 02:33 PM
Traditionally, melatonin supplements have been taken to induce a full night's rest, as well as aiding individuals in easing into a deep slumber. Since melatonin is a natural angiogenesis inhibitor, it actually has the ability to reduce the significance of tumors that are located within the body. The process of inhibiting angiogenesis is an essential part of treating cancer patients because it helps target the cells with oxygen. This helps regulate cell migration as well as invasion.
"A team of researchers from Iran suggests that melatonin has powerful anticancer properties."
Read more: https://www.naturalnews.com/2019-02-27-why-melatonin-is-a-powerful-anticancer-indolamine.html
Mountain ginseng found to have immunostimulating, antioxidant,anticancer and anti-aging properties
February 13, 2019 08:00 AM
Ginseng is a Chinese medicine, that has been long known for its medicinal properties. It is an expensive and scarce item. This makes it difficult to obtain for people who need it. Luckily, there is a solution to this problem. The Ginseng can be substituted by cultured roots of mountain ginseng. Studies have proven that mountain ginseng is a viable substitute. The general consensus of ginseng still holds, it have some risks as a supplement, but still has many health benefits. The article ends with a message to always consult a professional before taking ginseng as a supplement, just to be safe.
"In particular, cultured roots from mountain ginseng tissue have been identified as viable replacements for larger and cheaper production of the highly sought-after ginseng roots."
Read more: https://www.naturalnews.com/2019-02-06-mountain-ginseng-immunostimulating-antioxidant-anticancer-antiaging.html
Top 12 Super Foods That Fight Breast Cancer
October 26, 2017 12:14 PM
Breast cancer is a common killer of women and there are certain people who are at a higher risk of it. Men can get it as well. This info will help both sexes. It tells of some foods which can help fight this cancer. These foods are healthy anyway so should already be part of your diet. The cancer fighting properties are just extra. You'll get other health benefits as well. Eating a healthy diet is important for the management of many diseases.https://www.youtube.com/watch?v=L4KRCY3h4gA&rel=0
"Breast cancer is a disease caused by our bodies cellular unbalance"
The 5 health benefits of eating Millet you never knew
October 10, 2017 01:14 PM
Millet is a crop that is native to Africa and Asia, and is considered a primary source of both carbs and proteins for inhabitants close to where it is grown. Millet is garnering attention from scientists because it is almost impervious to insects and diseases, lending important components to the plant's potential positive impact of benefitting the health of those who ingest it. Millet has five main benefits, including anticancer attributes, it may play a pivotal role in stopping type 2 diabetes, it has a positive impact on the cardiovascular system, it may aid in partially lowering cholesterol, and finally, millet aids in positively impacting bowel health and movements.
"The nutritional value of Millet is also what is making this crop more attractive for western nations."
Read more: https://www.emaxhealth.com/13644/5-health-benefits-eating-millet-you-never-knew
Poblano Pepper: Fights Cancer & Boosts Fat Loss
June 09, 2017 09:14 AM
Food can play an important part in overall good health. The poblano pepper is fantastic tasting, a little hotter than a banana pepper but not as hot as a jalapeno pepper, and it's also filled with nutrients. Poblano peppers contain capsaicin, which is an antioxidant. Poblano peppers are also a good source of the vitamin B2. Capsacisin and B2 have properties that work to fight cancer. Capsaicin can also increase metabolism, which may lead to weight loss.
"Cultivars of peppers like the poblano also seem to have anticancer properties against oral cancer."
Read more: https://draxe.com/poblano-pepper/
Is Mushroom Coffee Even Better than Regular Coffee?
May 19, 2017 11:44 AM
There are many coffee alternatives out there and more are developed all the time. They're made from different roots, nuts, herbs, etc. One of them is mushroom coffee. This tells you if it is any good. It might be an option for those who can't have real coffee for health reasons. Some can't handle the caffeine found in real coffee. Others just like to try alternatives out of curiosity or to try finding the best tasting coffee.
"Prepackaged or instant mushroom coffee is also said to be lower in caffeine and less acidic than regular coffee"
Read more: https://draxe.com/mushroom-coffee/
Compound in hot peppers found to halt growth of breast cancer cells
April 16, 2017 12:59 AM
Discovering breast cancer is pretty rare yet it seem to be common. There is no cure for breast cancer unfortunately but oncologist are still searching for one daily. However, even though there is no cure there are certain to prevent cancer. For starters, living a healthy life daily is really a great way to prevent cancer because it will keeping your body cleaning. There is one ingredient to help prevent cancer that no on would have thought about and that is hot peppers. According to the article they stunt the growth of breast cancer cells.
"Capsaicin, an active ingredient that gives chilies and peppers their pungent taste, was shown to inhibit the growth of breast cancer cells, a study found."
Read more: http://www.naturalnews.com/2017-04-03-compound-in-hot-peppers-found-to-halt-growth-of-breast-cancer-cells.html
What Are The Health Benefits Of GrapeFruit Pectin?
January 16, 2013 01:46 PM
Benefits of Grapefruit Pectin
Grapefruit is a very nutritious fruit that is known to be rich in vitamin and mineral contents. But aside from that, grapefruit also contains grapefruit pectin which is a unique form of a soluble fiber. Pectin is actually a unique form of soluble fiber that can be found among fruits and vegetables. Pectin, as a supplement, is mainly extracted from apples and citrus peels such as that from grapefruits.
The following information will present some of the most significant health benefits of grapefruit. The water-soluble dietary fiber from grapefruit pectin is a type of natural fiber that can absorb water inside the stomach tract and all throughout the intestines. Water soluble fiber can soften stools and eventually induce defecation. Some common problems related to digestive system in which pectin can greatly help include constipation, hemorrhoids, irritable bowel disorder and some other diverticulitis diseases.
Grapefruit pectin is also considered as an excellent anticancer. Several studies have shown that pectin can inhibit the synthesis of the protein called gelatin-3 since pectin can easily bind with this protein. Taking fish oil supplements along with pectin supplement can suppress the development of colon cancer. Cholesterol reduction is yet another significant health benefit of grapefruit pectin. Pectin reduces LDL levels or low-density lipoprotein which is considered as bad cholesterol.
Therefore, taking pectin supplements is a good complimentary treatment for hypercholesterolemia or simply the case of having high cholesterol levels inside the body. Grapefruit has powerful antibacterial properties as well. They prevent problems caused by bacterial infections, internal fungi and some other harmful parasites. Grapefruit pectin can also slow down carbohydrate and glucose absorption. This helps to maintain a physically fit body and normal blood sugar levels. Although grapefruit pectin is truly beneficial for the body, this supplement must be taken properly.
Pectin soluble fiber just might interfere with other drugs and eventually leads to toxicity. That is why it is very important to consider seeing a doctor first before taking this natural supplement. Some people who are most likely not allowed to take pectin supplements are those that also take medications for hypertension, depression and diabetes.
November 12, 2012 01:52 PM
Lycopene is a carotenoid that is responsible for the red color in melon, tomatoes, rosehip, guava and pink grapefruits. it is known to be highly antioxidant meaning that it is very effective in neutralizing free radicals which could damage the body cells. Since its discovery in 1964 by Alex R. Torres, it has been observed that this compound is easily absorbed in the body when processed into sauce, juice, ketchup and paste. When consumed in the body, this product is deposited in the lungs, skin, colon, prostrate glands and the liver. There are numerous health benefits that are associated with consuming lycopene.
Free radicals in the body pose a major health risk as they are likely to steel molecules from healthy cells thus causing damage. In fact, these radicals have been associated with the cause of majority of the cancer infections. It is a strong antioxidant and it is able to stop these free radicals from damaging healthy cells.
Research has found that people who take products that contain lycopene regularly have reduced chances of getting heart diseases. It has also been observed that this compound can be used in the treatment heart diseases, osteoporosis, infertility and type II diabetes.
It has been found to posses numerous anticancer benefits. The compound helps the body against DNA damage which usually happens during the development stages of cancer. One of the ways through which lycopene is able to achieve this purpose is by blocking the interactions of stromal cells and tumors cells.
When the interaction is interrupted, the tumor and stromal tissues are inhibited from growing and developing. It is an indisputable fact that lycopene is a very important component in our lives. It is for this reason that medical practitioners advice people to consume carotenoid foods especially the ones that contain lycopene.
Flaxseed oil benefits
July 09, 2012 08:32 AM
Flaxseed oil is extracted from the flax plant which is native to Europe. The flaxseed plant has the botanical name of Linum Usitsissimum and also goes by the name linseed plant. The flax plant is an annual plant which grows to a height of around 1.2 meters. It has glaucous green leaves and normally produces pale blue flowers with five petals. The seeds from this plant are normally brown in color and are contained in a round capsule, these seeds are the ones normally used to produce flaxseed oil. Flaxseed oil has also very many health benefits associated with it.
Flaxseed oil extraction
Oil has to be first extracted from the flax plant before it can be used. The oil is usually obtained from the flax seed through a certain physical and chemical processes that are usually aimed at increasing its purity.
The normal procedure is usually to mechanically cold press the seeds so as to produce the oil. Solvent extraction usually follows up if the oil required is to have a high level of purity. The oil obtained is normally clear to yellowish color depending on the level of purity.
Components of flaxseed oil
Linseed oil or flaxseed oil is triglyceride in nature like many other types of essential oils. The main components of the oil include: Omega 3 fatty acid this acid is very essential to the body but has to be obtained from external sources since the body cannot make it. Omega 9 or oleic fatty acid, Omega 6 fatty acid or linoleic acid, Vitamin E which acts as an antioxidant for the body system.
The combined effect of these compounds usually provides the body with a lot of health benefits. The health benefits associated with linseed oil have been known for thousands of years and there is documented cases of its use amongst the ancient Romans.
Some of the benefits associated with linseed oil include Cardiovascular well being.
This is one of the most important health benefits associated with the use of this kid of oil. Omega 3 or alpha-linoleic fatty acid is the compound which is attributed to a healthy heart and cardiovascular well being of an individual. This fatty acid acts as a lubricating cushion and hence helps to counteract the stresses the body might undergo. It also has anti inflammatory properties.
It is also important in maintaining the rigidity of cell membranes and also lowers the amount of harmful cholesterol within the body.
The omega 3 that is contained in flaxseed oil has got anti inflammatory properties that makes it an effective tool against arthritis as it reduces the inflammation of joints.
Reduces risk of cancer
Vitamin E contained within flaxseed oil has got anti-oxidant properties which make sit effective against the occurrence of cancer. Omega 3 has also got anticancer propertiesHealthy skin The compounds that make up flaxseed oil are very effective in the elimination of eczema and acne. Therefore, the use of cosmetic products which have linseed oil incorporated in them can go a long way in ensuring that an individual has a young and beautiful skin.
Increases calcium absorption
Research has shown that linseed oil increases calcium absorption within the body. This is very important for women who are in the post- menopausal period as their bone density normally drops during this period and they require increased calcium intake. Linseed oil has also instrumental in burning calories and also increases the body's metabolic rate. It is therefore recommended that an individual should incorporate this oil into h9is or her diet.
What Is Silymarin And What Are Its Health Benefits?
April 11, 2012 07:29 AM
Silymarin a Component of Milk thistle
Silymarin refers to a dietary supplement that is derived from the seeds of the milk thistle plant, whose scientific name is Silybum marianum. Milk thistle is native to Southern Europe, Middle East and North Africa, but it has also been naturalized in North America. The name of the plant is derived from the white, milky sap from its leaves and stems once they have been broken. Silymarin is made up of three types of plant flavonoids, namely silibinin, silicristin and silidianin. These work together as Silymarin, providing several health benefits to people. The medicinal benefits of Silymarin are not a recent discovery, since extracts of the milk thistle have been used for centuries in the treatment of liver diseases. Currently however, the benefits of Silymarin are not restricted to the treatment of liver conditions. With time, it has emerged that Silymarin has other health benefits, which will be discussed in this article.
One of the best known health benefits of Silymarin is its protection of the liver against toxins. The liver is one of the most important organs in a person's body, aiding in food digestion in addition to cleaning toxic substances from the blood. This means that the diseases that affect a person's liver will also affect his or her overall health. One of the most serious diseases that affect the liver is hepatitis, a viral infection that causes liver inflammation. Research has shown that Silymarin inhibits the development of the hepatitis virus, since it has antioxidant and anti-inflammatory properties. It also stimulates the body's immune system, providing overall liver protection.
Silymarin also has anticancer benefits, owing to its antioxidant properties. Antioxidants normally prevent the damage of healthy body cells by free radicals. According to the American Cancer Society, the antioxidant properties in Silymarin offer protection against skin cancer. Further, Silymarin also helps to reduce the growth of prostrate, breast and cervical cancer cells. This means that when used together with other cancer treatments, it can actually help to prevent or reduce a patient's need for chemotherapy. It is also useful in the treatment of cancer, due to the fact that it protects the liver from the toxins in the chemotherapy drugs.
Other than chemotherapy drugs, Silymarin also protects the liver against any other drugs that may affect the liver, as well as harmful substances such as alcohol. In some parts of Europe, milk thistle is normally given to patients whose medications are known to cause liver complications. The other benefit of Silymarin is that is helpful on controlling the blood sugar levels. In a study involving patients with type II diabetes, it was found that taking Silymarin at least thrice a day significantly reduced their blood sugar levels. In addition, the patients also experienced a drop in the levels of bad cholesterol.
Silymarin has no toxic compounds, so it is safe to use without any serious side effects. The only side effects that have been reported are indigestion, diarrhea and allergic reactions. However, the prevalence of such occurrences is negligible, as they only apply to few people. Nevertheless, people with existing medical conditions should consult their doctors prior to taking Silymarin.
What Makes Curamin Such A Good Natural Pain Remedy?
March 07, 2012 06:57 AM
Curamin: A Natural Anti-Inflammatory
When nerve endings become irritated, they cause pain. This is because of factors such as lack of sleep, hormonal imbalance, stress, nutritional imbalance, etc. Pain is generally symptomatic of some dysfunction or inflammation in our body and the first reaction for those suffering from it is to reach out for a pain killer. This is where Curamin comes in.
Curamin is a proprietary formula and a curcumin based supplement. Curcumin is a beneficial compound found in turmeric, a popular Indian spice. Turmeric has been used since centuries in the field of alternate medicine like Ayurveda because of its many medicinal properties. The compound, curcumin in fact, has the ability to reduce pain by supporting the body's ability to respond to swelling and inflammation. It has been found equivalent to some popular allopathic pain killers. Apart from this, it also has antioxidant, antibacterial, antiviral, antifungal and anticancer properties and has been found to promote anti depressant and cognitive enhancement benefits.
Curamin is a product having a formula based on this particular compound of turmeric and is therefore extracted out of natural ingredients and has been found to have minimal side effects. Curamin, apart from other ingredients, also contains a strain of curcumin that has a high absorption factor which makes it several times more effective and stronger than plain curcumin products. It not only balances the body's response to inflammation but also has been observed to have a consistent and long lasting effect. Therefore, this makes curamin the most effective form of curcumin available.
Studies have established that curamin is safe and does not interfere with kidney, liver or stomach functions. The safe dosage recommended by the company is two pills twice a day for pain alleviation and not more than 8 pills within a 24-hour period. An overdose of such herbal products may sometimes cause intestinal discomfort at the most.
Main Ingredients of Curamin
Curamin has four principle ingredients that have an overall effect on inflammation caused in the bones and joints due to arthritis or overuse and exercise. These ingredients include: DL-phenylalanine or DLPA is a two part amino acid that acts as a positive mood enhancer by preventing the breakdown of enkephalin compound and also helps in the production of brain chemicals like dopamine and norepinephrine. Boswellia that helps to prevent the activity of the inflammatory enzyme. Curcumin which helps block multiple pathways within the body to retard and stop inflammation. Nattokinase which is an enzyme that helps the fast absorption of the ingredients through the body by promoting blood flow and improving circulation.
Benefits of Curamin
Curamin has helped people suffering from problems like arthritis, migraines, bursitis, and soreness caused by accidents or injuries. It also helps build resistance and immunity to inflammation concerned especially with the bones and joints.
Curamin, being a plant based product has no toxic effects and is available with many natural medicine practitioners and pharmacies. It is a very effective natural alternative to allopathic drugs and painkillers that over a long term use cause many side effects, some of which are potent.
If you are in pain, try curamin today!
Periwinkle - Vinpocetine
October 09, 2009 10:23 AM
Periwinkle can be found natively growing in North America, Europe, China, and India. The plant is a semi woody evergreen perennial. It is known by three names: Vinca, Periwinkle, and Myrtle. Typically, the plant is grown as an annual. It has a woody stem that can be found near the base and grows two to three feet tall and spreads out just as wide. The plant has a long life span of approximately twenty years. It also has a moderate growth rate. The plant has dark green foliage and bright blue flowers. The leaves are retained from year to year and are about two to three inches in length. This plant is very easy to grow, requiring little or no attention. Typically, it does best in poor, well drained soils. The flowers will suffer if the soils are too fertile. The periwinkle plant needs full sun or partial shade. It should be watered moderately during the growing season, but it is relatively drought resistant once it is established. The plant does not tolerate over watering. Fungus problems can occur in humid or wet weather.
For centuries, periwinkle has been used in different areas of the world to treat a variety of conditions. This herb grows in temperate climates and is often grown as an ornamental plant. Periwinkle juice from the leaves of the plant is used in India and applied to bee stings and bug bites. The plant grows well in Hawaii. The extract has been applied to wounds to stop bleeding. This herb can be found growing in South America and has been used for a wide variety of medicinal purposes. Periwinkle was used by native healers in Madagascar for cancer. Vincristine sulfate and vinblastine sulfate, two anticancer drugs, were developed from the periwinkle plant after the herbal healers in Madagascar were studied.
Periwinkle is considered to be a good binder. It can be chewed to stop bleeding in both the nose and mouth. It has been used historically for female complaints including excessive menstrual bleeding and uterine discharge. It also helps in aiding blood coagulation in wounds. This herb is effective in treating colitis, diarrhea, hemorrhoids, high blood pressure, headaches, migraines, nervous conditions, and diabetes.
Studies have found that periwinkle possesses anticancer attributes. Anticancer agents in periwinkle have been used to treat Hodgkin’s disease, leukemia, and cancer of the lungs, liver, and kidneys, along with other types of cancer. Periwinkle can be found natively growing in North America, Europe, China, and India. The plant is a semi woody evergreen perennial. It is known by three names: Vinca, Periwinkle, and Myrtle. Typically, the plant is grown as an annual. It has a woody stem that can be found near the base and grows two to three feet tall and spreads out just as wide. The plant has a long life span of approximately twenty years. It also has a moderate growth rate. The plant has dark green foliage and bright blue flowers. The leaves are retained from year to year and are about two to three inches in length. This plant is very easy to grow, requiring little or no attention. Typically, it does best in poor, well-drained soils. The flowers will suffer if the soils are too fertile. The periwinkle plant needs full sun or partial shade. It should be watered moderately during the growing season, but it is relatively drought r
The entire periwinkle plant is used to provide antineoplastic, astringent, hemostatic, nervine, and sedative properties. Primarily, periwinkle is extremely beneficial in dealing with cancer, diabetes, hemorrhoids, nervousness, and ulcers. Vincamine is an alkaloid found in this plant has been studied and found to support cerebral blood flow, and oxygen and glucose utilization. It may also support cognitive function and enhance memory and concentration when taken regularly.
Additionally, the herb is very helpful in treating bleeding, congestion, chronic constipation, cramps, dandruff, chronic diarrhea, internal hemorrhages, leukemia, menstrual bleeding, excessive mucus, nightmares, skin disorders, sores, and toothache. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by periwinkle, please feel free to consult a representative from your local health food store with questions.
Red Clover Blossom
August 29, 2009 01:51 PM
Red clover is also commonly referred to as wild clover, purple clover, meadow clover, honeysuckle clover, or cow grass. This herb is a member of the pea family. It is commonly found in pastures, lawns, along roadsides, and in meadows. Many consider this herb to be a nuisance and, thus, they try to eliminate it from their lawns. However, this is not easily accomplished due to red clover’s hearty nature.
The use of red clover most likely originated in Europe. There, it was used as an expectorant and a diuretic. Additionally, it was burned as incense to invoke the spirits of the deceased. Some people even wore the leaves of red clover as charms against evil. The red clover was revered by early Christians because they associated its three leaves with the Trinity. The flowers of this plant were dried by the ancient Chinese and then put in pillows to help relax both the body and mind. The Native Americans used red clover as an infusion gargle for sore throats, whooping cough, and asthma. Additionally, they used it on children because it was a milder, safer way to fight debilitating childhood diseases.
This herb has been used for treating cancer, bronchitis, nervous conditions, spasms, and toxins in the body. It is considered by herbalists to be a blood cleanser. Herbalists also recommend this mild herb in formulas when using a cleansing program. Red clover is often mixed with honey and water to make a cough syrup and act as an expectorant. The herb is a mild sedative and is useful for spasmodic conditions, bronchitis, wheezing, and fatigue. Because red clover is mild, it can often be used by children.
Research has determined that red clover contains some antibiotic properties that are beneficial in fighting several kinds of bacteria. Among these types of bacteria is the one that causes tuberculosis. Additionally, red clover has a long history of use in treating cancer. Scientists at the National Cancer Institute have uncovered some anticancer activity in red clover, including daidzein and genistein activity. Even though the findings are preliminary and the use of red clover as a cancer treatment has not yet been validated, research is continuing to show promising results.
Externally, red clover has been used to treat skin problems such as acne, psoriasis, eczema, and even vaginal irritation. It can also be applied topically to burns, boils, sores, and ulcers. Red clover has also been documented for use in treating AIDS, syphilis, and leprosy. This herb can be applied externally to help soothe lymphatic swelling and as an eyewash.
In short, the flowers of red clover are used to provide alterative, antibiotic, antispasmodic, blood purifier, nutritive, sedative, stimulant, and vulnerary properties. The primary nutrients found in red clover are calcium, cobalt, copper, iron, magnesium, manganese, nickel, selenium, sodium, tin, and vitamins A, C, B-complex, F, and P. Primarily, red clover is extremely beneficial in dealing with acne, AIDS/HIV, athlete’s foot, blood impurities, bronchitis, cancer, eczema, leukemia, liver disorders, nervous disorders, psoriasis, skin disorders, spasms, and the effects of toxins.
Additionally, this herb is very helpful in treating arthritis, asthma, boils, burns, childhood diseases, colds, constipation, coughs, muscle cramps, fatigue, flu, gallbladder, gastric disorders, indigestion, leprosy, lymphatic irritations, rheumatism, sores, syphilis, sore throat, tuberculosis, ulcers, urinary infections, vaginal irritations, whooping cough, and wounds.
For more information on red clover, look for this wonderful herb at your local heath food store. Remember to always look for name brands to ensure quality and purity of the product you purchase.
July 28, 2009 11:32 AM
Saffron was used by the Greeks and Chinese as a royal dye because of its yellow color. Wealthy Romans used this herb to perfume their homes. In Europe, it was used medicinally between the fourth and eighteenth centuries. It was also being used in the kitchen to cook with.
In the book The Complete Herbal, Nicholas Culpeper recommended using saffron for the heart, brain, and lungs. The herb was also suggested for acute diseases like smallpox and measles. It was also recommended for hysteric depression. Dr. David Culbreth characterized the herb as a pain reliever and was said to promote perspiration and gas explosion and ease painful menstruation in the book Materia Medica and Pharmacology. Saffron was also said to relieve eye infections and encourage sore eruptions.
This herb is soothing to both the stomach and colon. It is responsible for acting as a blood purifier. Saffron helps stimulate circulation and regulate the spleen, heart, and liver. It is also helpful in reducing inflammation; treating arthritis, gout, bursitis, kidney stones, hypoglycemia, and chest congestion; improving circulation; and promoting energy. Small doses should be taken internally for coughs, gas, and colic and to stimulate appetite. The herb can also be applied externally in a salve for gout.
It has been shown that saffron may even help to reduce cholesterol levels. It neutralizes uric acid buildup in the system. Recent research determined that rabbits, which were fed crocetin, which is a component of saffron, had a significant reduction in cholesterol and triglyceride levels. Saffron is eaten daily in Valencia and Spain, resulting in little heart disease occurring among inhabitants. The evidence has shown that saffron increases oxygen diffusion from the red blood cells. Not only does it discourage uric acid buildup, it also inhibits the accumulation of lactic acid. Therefore, it may help prevent heart disease.
Other research done on saffron suggests that the crocetin ingredient may have the potential to act as an anticancer agent in studies done both in vitro and in animals. On study that was done using saffron extract in vitro found that tumor colony cell growth was limited by inhibiting the cellular nucleic acid synthesis. Additional research on cancer has found that saffron that was given orally helped in increasing the life span of mice with variety of laboratory-induced cancers.
The flowers of the saffron plant are used to provide alterative, anodyne, antineoplastic, antispasmodic, aphrodisiac, blood purifier, carminative, diaphoretic, emmenagogue, expectorant, sedative, and stimulant. The primary nutrients found in this herb are calcium, lactic acid, phosphorus, potassium, sodium, and vitamins A and B12. Primarily, saffron is extremely beneficial in treating fevers, gout, indigestion, liver disorders, measles, excessive perspiration, phlegm, psoriasis, rheumatism, scarlet fever, and stomach acid. Additionally, this herb is very helpful in dealing with appetite loss, arthritis, blood impurities, bronchitis, cancer, colds, conjunctivitis, coughs, fatigue, gas, headaches, heartburn, uterine hemorrhages, hyperglycemia, hypoglycemia, insomnia, jaundice, kidney stones, menstrual symptoms, skin disease, tuberculosis, ulcers, water retention, and whooping cough.
In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by saffron, please feel free to consult a representative from your local health food store with questions. Saffron is available at your local or internet health food store. Note: Saffron should not be consumed internally.
Colostrum, Vitamin C, Echinacea, Goldenseal, Pau D'arco, Garlic, Astragalus
June 19, 2009 11:05 AM
There are many supplements and herbs that compliment the supplementation of colostrum. Among these are Echinacea, vitamin C, garlic, goldenseal, pau d’arco, astragalus, and beta carotene (vitamin A).
Echinacea is one of the most well-known and respected herbal supplements when it comes to the maintenance and strengthening of the immune system. Various Echinacea species have yielded an impressive variety of chemical constituents which possess pharmacological properties. This suggests that there is some form of synergistic action that occurs between the compounds in order to achieve therapeutic benefits. The main therapeutic properties are found in polysaccharides, flavonoids, caffeic acid derivatives, essential oils, polyacetylenes, and alkylamides. These constituents are responsible for a large number of immuno-stimulatory, anti-inflammatory, antiviral, antibacterial, and anticancer properties.
Echinacea has several effects on the immune system, including the alternate complement pathway, which enhances the movement of white blood cells into the areas of infection. Echinacea also affects many of the immune system’s cells that are responsible for slowing viral and bacterial infection. The aerial portion of Echinacea is known to be effective in warding off viruses such as influenza, herpes, and vesicular stomatitis, by blocking virus receptors on the cell surface. Echinacea is also able to indirectly kill viruses by encouraging the production and release of interferon, which is a substance that is capable of blocking viral RNA.
Vitamin C is one of the most well-known nutrients for promoting basic immune functions, with its benefits being known for many years. It is effective in reducing the severity and duration of colds and flu. Also, it has the ability to act as an immuno-stimulant by enhancing white blood cell production, increasing interferon levels and antibody responses, promoting the secretion of thymic hormones, and improving connective tissue. Vitamin C can be found abundantly in various fruits in vegetables, which means that it can often be consumed in acceptable amounts without supplementation through broccoli, sweet peppers, collards, cabbage, spinach, kale, parsley, melons, potatoes, tangerines, and Brussels sprouts, just to name a few.
Garlic is one of the most commonly used medicinal herbs, as it is found throughout the world and has been employed for various therapeutic purposes for thousands of years. Commonly used in Chinese herbal medicine and ayurvedic medicine, it has recently received much attention in the US media as well as other Western countries. Recent research has found that garlic possesses some powerful capabilities when it comes to the immune system and the body’s ability to fight infection. Garlic produces antiviral and antibacterial capabilities that stimulate and improve performance by the body’s immune systems. Additionally, garlic kills viruses and protects the body from invading virus cells by enhancing the body’s immune functions.
Goldenseal is native to North America, where it helps with a wider variety of ailments, including infection. Goldenseal is effective in combating invasion of colds and flu by stimulating the immune system and the activity of macrophages, which are one of the body’s defense mechanisms against viruses, bacteria, cancer cells, and other invaders.
Pau d’arco is also known for its powerful antiviral, antibiotic, and immune system enhancing capabilities. It has been shown to actively inhibit the activity of several viruses such as: both herpes viruses, the influenza viruses, polioviruses, and vesicular stomatitis virus.
Astragalus, which is extremely popular in Chinese herbal medicine, is an immune system enhancer. It has the ability to reduce the severity and length of the common cold through its application. Vitamin A, which has long been known to be effective in fighting infectious diseases, has antiviral and antibacterial capabilities. Vitamin A deficiencies can manifest themselves through increased infection by cold and flu viruses.
Along with the above, it is also important to eat healthful foods (fruits and vegetables), drink plenty of fluids, exercise, avoid smoking, avoid consuming alcohol, get plenty of rest, and reduce stress in order to increase the benefits that colostrum supplementation provides. Natural supplements can help boost the immune system and help one live a healthier longer life.
June 16, 2009 09:46 AM
Chickweeds are an annual herb that can be found growing in temperate zones, artic zones, and throughout. The most likely origin of this plant, although not known for sure, is Eurasia. Chickweeds have established themselves all over the world, as they may have been carried by clothes and shoes of explorers. Chickweed plants are as numerous in species as they are in region. Most species are succulent with white flowers. All of the species have practically the same edible and medicinal values.
This plant exhibits an interesting trait, as it folds its leaves over its buds and the new shoots every night. This event is known as the sleeping of the plant. Cultivating this plant is not exactly necessary, as it is abundant and easy to find. The plant can be gathered fresh and edible between May and July, as soon as the flowers appear. Not only can the plant be used fresh, it can also be dried for later herb use.
Chickweed can be found growing abundantly in areas of Europe and North America. The Ojibwe and Iroquois Native American tribes used chickweed as eyewash. They also used it in poultice form to heal wounds. It has recently been studied for its abilities in helping to prevent cancer.
Chickweed is extremely valuable in treating blood toxicity, fevers, and inflammation. Its mucilage elements are known to help with stomach ulcers and also inflamed bowels. Chickweed is great for helping to dissolve plaque in blood vessels as well as other fatty substances that can be found in the body. Chickweed acts as an antibiotic in the blood, as it may be recommended as an anticancer treatment. Some people have used chickweed to treat tumors.
Chickweed can be used as a poultice for boils, burns, skin diseases, sore eyes, and swollen testes. Chickweed is also recommended to aid in weight loss and to break down cellulite. This herb is mild and has been sued as a food as well as a medicine.
Chickweeds are very nutritious and high in vitamins and minerals. They can be added to salads or cooked as a pot herb. The plant tastes somewhat like spinach. The whole plant can be taken internally as a postpartum depurative, emmenagogue, glactogogue, and cirucaltory tonic. A decoction can also be used externally to treat rheumatic pains, wounds, and ulcers. Chickweed can be applied as a medicinal poultice to relieve any kind of roseola. It is effective wherever there are fragile superficial veins or itching skin conditions.
The entire chickweed herb is used to provide alterative, anorectic, antineoplastic, blood purifier, demulcent, diuretic, emollient, expectorant, febrifuge, mucilant, nutritive, pectoral, and stomachic properties. The primary nutrients found in this herb are calcium, copper, iron, manganese, phosphorus, sodium, vitamins C, D, and B-complex, and zinc. Primarily, this herb is extremely beneficial in dealing with excessive appetite, bleeding, blood impurities, convulsions, obesity, skin rashes, and ulcers. Additionally, chickweed can be extremely helpful in treating arteriosclerosis, asthma, bronchitis, bruises, bursitis, colitis, constipation, cramps, eye infections, gas, hemorrhoids, lung congestion, excessive mucus, pleurisy, blood poising, swollen testicles, inflamed tissue, water retention, and wounds. For more information the many beneficial affects of chickweed, please feel free to contact a representative from your local health food store with questions.
Chickweed is available in capsule and tablet forms at your local or internet health food store. Look for name brands like Solaray, Natures Answer, and Natures Herbs to ensure quality and purity of the products you purchase.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Chickweed is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
Cold And Flue Remedies
March 16, 2009 03:42 PM
Echinacea, zinc, vitamin C, and garlic are all the most well-known and respected supplements concerning the maintenance and strengthening of the immune system. Echinacea contains polysaccharides, flavonoids, caffeic acid derivatives, essential oils, polyacetylenes, and alkylamides, which contribute to the herb’s therapeutic benefits. These constituents are responsible for a variety of immuno-stimulatory, anti-inflammatory, antiviral, antibacterial, and anticancer properties.
Echinacea possesses the ability to enhance the movement of white blood cells into infected areas of the body. Echinacea also affects many of the immune system’s cells that are responsible for slowing viral and bacterial infection. Additionally, this herb enhances the performance of macrophages in the immune system, which are responsible for engulfing foreign material like bacteria, viruses, and dead cellular matter. Echinacea also has the ability to kill viruses that indirectly encourage the production and release of interferon, which is a substance that potentially blocks the transcription of viral RNA.
Zinc has been recognized for an extended amount of time as a protection against colds. It is well known that zinc deficiencies are linked to immune system-related disorders as well as the increased susceptibility to infectious diseases. Zinc throat lozenges have become very popular in treating colds over the last few years. One recent study found that zinc is not only beneficial to the immune system, but also necessary for its optimal function.
Vitamin C is one of the most well-known nutrients for battling the effects of colds and flu. Its benefits have been known for years, with a large body of research indicating its effectiveness in reducing the severity and duration of colds an flu. Additionally, vitamin C acts as an immunostimulant by enhancing white blood cell production, increasing interferon levels and antibody responses, promotes secretion of thymic hormones, and improves connective tissue.
There is conflicting information on how much vitamin C one should take, but most experts agree that the FDA’s recommended dietary intake is not sufficient. Many doctors suggest taking large doses, as much as 10,000 mg when suffering from a cold or flu. One of the great things about vitamin C is that it can be found abundantly in many fruits and vegetables. The best food sources include broccoli, sweet peppers, collards, cabbage, spinach, kale, parsley, melons, potatoes, tangerines, and Brussels sprouts.
Garlic, which is extremely well known as a culinary additive, is actually one of the most commonly used medicinal herbs as it is found throughout the world and employed for various therapeutic purposes for thousands of years. It is common in Chinese herbal medicine and has recently received a great deal of attention in the U.S. and other Western countries. Recent research has found that garlic possesses powerful capabilities relating the immune system and the body’s ability to fight infection. Garlic possesses antiviral and antibacterial capabilities and has been shown repeatedly to simulate and improve performance by the body’s immune systems. Studies on garlic have shown that it has the ability to actually kill flu and cold viruses. Garlic also can protect the body from invading virus cells by enhancing the body’s immune functions.
Additional herbs and natural supplements that are useful in fighting cold and flu viruses include goldenseal, pau d’arco, astragalus, licorice, peppermint, and beta carotene. No matter what you choose to do by way of a doctor or natural alternative, supplements such as these discussed have zero side effects if taken as recommended on the bottles label. Natural vitamins and herbs can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
Red Pepper, Cayenne, Capsicum
December 18, 2008 04:51 PM
A remarkable whole body stimulant, Capsicum can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain, and fight off infection. One study on African plants found that Capsicum, when regularly ingested, is highly beneficial in hemorrhoids varicose veins, anorexia, liver congestion, and vascular conditions. The therapeutic actions of capsicum can be attributed to the alkaloid or glucoside content of the herb.
Capsicum boosts peripheral circulation and stimulates organ secretion as it expedites the therapeutic delivery and action of other herbs. This allows the medicinal benefits of these herbs to reach the inflamed tissue more rapidly because of enhanced blood flow. Cayenne insures rapid and even distribution of the active parts of the rest of the herbs to critical parts of the body, which include those that are involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation.
For this reason, cayenne is included in many other blends, as even extremely small quantities can dramatically increase the efficiency of most other herbs. Capsicum stimulates everything from blood flow to peristaltic action in the stomach, to intestinal transit time. Capsicum’s ability to stimulate organ secretion and heart action makes it one of the strongest natural stimulants that are known.
Capsicum is also known to be unequaled in its ability to boost circulation and increase heart action. Cultures that consume significant amounts of cayenne pepper in their diets have been found to have lower rates of cardiovascular disease. A variety of desirable actions on the entire cardiovascular system can be produced by Capsicum, with its extraordinary ability to enhance cardiovascular performance and lower blood pressure. Capsicum is considered a superior food for the heart by herbalists, where capsicum in hot water is thought to help lessen the severity of heart attacks.
Many studies have also been done on Capsicum’s ability to reduce the risk of developing atherosclerosis by reducing blood cholesterol and triglyceride levels. When cayenne is ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels that ordinarily results was significantly inhibited. Additionally, bile acids and free cholesterol were subsequently eliminated from the body through the stool.
Another bonus of Capsicum is its ability to lower blood serum cholesterol, as it decreases blood pressure. There is additionally evidence that suggested that the herb is able to initiate other mechanisms that help in fighting hypertension. Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it is not shocking that is also facilitates the faster removal of toxins from the blood stream and lymphatic system.
Additional benefits of Capsicum include its ability to boost the circulatory system, as it has the ability to help in preventing cold hands and feet, as well as Reynaud’s Syndrome. Capsicum also has antioxidant capabilities, making it a great scavenger of free radicals. Anti-cancer research has also found that Capsicum does demonstrate anticancer properties, as it inhibits certain enzymes that initiate the mutation of cells. This implies that taking Capsicum can give the body some protection against cellular mutation.
Capsicum has also been found to be an impressive pain killer, an anesthetic to ulcerated tissue, an aid in weight loss, a helper in psoriasis and rhinitis, and a reliever of fevers and chills. The list goes on and on, about the benefits of this amazing herb. Cayenne or red pepper can be found at your local health food store.
Polyphenols is an Antioxidant
October 13, 2008 02:14 PM
A lot of new evidence suggests that consuming more plant polyphenols is a powerful way to protect aging arteries. These polyphenol compounds help improve endothelial function, a critical factor in preventing atherosclerosis; inhibit abnormal platelet aggregation which causes most sudden heart attacks and strokes; fight inflammation; and support healthy blood lipids. Polyphenols that are of particular interest are those derived from green tea, cocoa, apples, and black chokeberry, which all complement each other in helping to build the body’s defenses against various ailments.
All throughout history, the medicinal potential of plants has been celebrated. Modern science has found that edible plants are to be valued for their high vitamin and fiber along with their rich store of polyphenols. Polyphenols are found in fruits and vegetables, as well as cocoa, tea, and chokeberry and have been shown to be a type of chemical that may protect the body against some common health problems as well as certain effects of aging. Polyphenols protect cells and body chemicals against damage that is caused by free radicals and block the action of enzymes that cancers need for growth, deactivating substances that promote the growth of cancer. The increased consumption of polyphenols has been associated with a reduced risk of cardiovascular disease and potentially cancer and stroke.
In Aztec culture, cocoa was one of the most highly prized due to its medicinal and stimulant value, along with its taste. The polyphenols found in cocoa occur in a higher concentration than can be found in any other food. They also have antioxidant activity much greater than those found in broccoli or red wine. The catechins and procyanidins that are found in cocoa seem to lower the risk of cancer and heart disease. Cocoa has also been proven in studies to reduce blood pressure, improve insulin sensitivity, and slightly ameliorate the lipid profile. Although cocoa is a healthy and tasteful food, it is high in caloric content and therefore, its ingestion must be accompanied by the careful reduction of calories from other sources.
Many studies have shown that tea polyphenols can be extremely beneficial to human health, possessing anti-obesity, antihypertensive, anti-diabetic, antioxidant, anti-inflammatory, and anticancer effects. Tea is the world’s second most consumed beverage, although less popular in the Western diet. Green tea and white tea retain more polyphenols in their intact form, as oolong and black teas undergo more extensive processing before they are marketed. Tea polyphenols break down in high temperatures therefore; freshly brewed tea contains a higher amount of polyphenols per serving than do tea drinks that are canned or bottled.
Similar to the blueberry, the black chokeberry is high in anthocyanins and antioxidant activity. It is native to eastern North America and has become popular in Eastern Europe and Russia due to its health-promoting potential. This berry protects the liver from chemical poisoning and the stomach lining from ulcers. It also acts as an anti-inflammatory, lowers harmful cholesterol levels, and prevents dangerous swings in blood pressure. Some studies have shown that this berry seems to prevent the harmful mutations in cell cultures, regulates immune function of human white blood cell cultures, and suppressed the growth of human colon cancers.
DIM For Estrogen Balance
July 10, 2008 03:26 PM
Diindolylmethane from broccoli can help with estrogen balance: There is plenty of evidence to suggest that, but before discussing the whys and wherefores, let's first have a look at the substance, where it comes from and why it should have any effect on estrogen or its balance.
Diindolylmethane is an indole contained in brassicas such as broccoli, cabbage, kale, brussel sprouts and cauliflower. It is a dimer of indole-3-carbinol, which is itself formed by the autolytic degradation of glucosinolate glucobrassicin which is found in brassicas. Both this and the dimeric diindolylmethane are currently being tested for their antioxidant, anticancer and antiatherogenic properties, although this type of research has been mainly made on animals. When the cell walls of brassicas are ruptured, the enzyme myrosinase is released, that breaks down the glucobrassicin.
Because diindolylmethane is oil soluble it is more bioavailable to the body in the presence of vitamin E and other lipophilic substances, and these are normally included in oral supplements. However, back to estrogen and its effects upon human estrogen balance. Estrogen is the name for a group of steroids that function substantially as the female sex hormone. They have many effects on the body, including regulation of the menstrual cycle, breast development and promote the formation of secondary female characteristics such as reduced height and muscle mass.
Estrogen is also present in the male, where it regulates several factors pertaining to the reproductive system. It does not, however, take part in the process that determines sexual desire. If all of these properties are considered it would seem logical to believe that estrogen levels could be used to control weight increase, although claims that it can be use to enhance sexual performance seem ill founded: based more on hope than on science!
What science appears to have found, however, is that estrogen dominance, due to an imbalance between estrogen and progesterone levels in the body, can give rise to increased weight, and even obesity, in women. It can also lead to uterine, ovarian and breast cancers, and cervical dysplasia which, while not cancer, can give rise to cervical cancer if not treated. Estrogen imbalance, therefore, is not good news and something to be avoided if it possibly can. So what can be done to avoid it?
The answer is to find a hormonal balance, and this is where diindolylmethane (DIM) comes in. The substance has been found to have a positive effect on the balance between estrogen and progesterone, although eating broccoli will not be sufficient to do the job properly. Insufficient DIM is released by breaking the cell walls of broccoli through chewing to have much effect on the balance, about a kilo of broccoli a day being needed to have any noticeable effect. It is the diindolylmethane supplements that are able to have the desired effect in restoring the hormone balance and eliminating the undesirable effects of estrogen imbalance.
But why should estrogen imbalance occur? What are the factors that cause this dangerous condition, and if it is so common how did our ancestors manage without today's science? The answer to the second question lies in that to the first, but before we discuss that don't go thinking that your ancestors managed through thick and thin. Perhaps yours did, but your life expectancy is significantly greater than that of your parents when they were born. In fact, you don't have to go too far up your family tree to when you would be doing well if you hit forty! So the argument about your ancestors doesn't wash.
In fact, an estrogen imbalance can be caused by several factors: a slow estrogen metabolism that leads to an excess of estrogen because it is not broken down quickly enough is common, but far more common is the effect of pollutants such as pesticides, car exhaust fumes, emulsifiers, household cleaners and even some soaps. They contain chemicals known as xenoestrogens that our body believes to be real estrogens. They can stick to estrogen receptors on healthy cells, and can also prevent true estrogen from binding to the cell it should bind to. This results in an increase in free estrogen that cannot bind to the estrogen receptors that it should. Your ancestors did not have these problems with such 'estrogen mimics' and so managed just fine.
There is also the fact that estrogen can be broken down in the liver by means of two different routes: one leads to a form of estrogen that metabolizes to provide many benefits, such as strong bones and a reduction in heart disease, while the other has the opposite effect of causing cancers, depression, osteoporosis and problems with your immune system. That is by no means the full list: you don't want to see that, believe me!
You might think that if estrogen is dominant over progesterone, then taking progesterone would resolve the problem. It would seem to be a good cure. In fact, it is not a good idea since progesterone can be metabolized into yet more estrogen, making the problem even worse. The real answer is to take a supplement containing the substance that solves the problem by changing the estrogen metabolism pathways in the liver: diindolylmethane. More of the so-called "good" estrogen metabolites are formed, and less of the bad. The actual estrogen levels are not changed, but the way in which the excess estrogen causes harm is changed. That way, it doesn't matter what the imbalance is, the estrogen cannot do ham to your body.
DIM possesses many potential positive benefits when used as a supplement. It can reduce your chances of getting breast, cervical and ovarian cancers, and also acts as a strong antioxidant, and helps to strengthen your immune system. It might help you to lose weight, but more studies are needed before this can be claimed conclusively. However, there is evidence at the moment that it has a weight reducing effect.
Its effect on sexual health is largely unfounded, but the effect of a placebo in this area can be astounding: that indicates how much psychology has to do with sexual performance. Nevertheless, the known and projected benefits of diindolylmethane are so significant that taking a supplement would seem a reasonable thing to do, and although your mom was right about you eating your broccoli, brassicas alone are not a rich enough source for a significant effect.
Fruit and Vegetable Lightning drink mixes from Natures Plus
February 06, 2007 02:41 PM
Enjoy the Rainbow – the Color Wheel of Fruits and Vegetables
We’ve all heard the statistics, and have probably seen the signs in the produce section of our favorite grocery store: eating 5 servings of fruits and veggies a day is important,
Chances are also pretty good that we’ve also seen the newest food pyramid, encouraging Americans to “eat a rainbow of frits and vegetables.” That is, choose from the rich variety of colors for the best all-around health benefits.
In this Ask the Doctor, we’re going to look at the unique health components of different colored fruits and vegetables, and why they’re so important. Plus, we’ll learn about supplemental options, like fruit and vegetable drink mixes, for those days when our diets just aren’t that great.
Q. What’s the big deal about fruits and vegetables?
A. Well, for the main reason that they are whole foods – created by nature (or at least generations of farming) and are rich in a variety of nutrients. Processed foods can’t match the health benefits of strawberries or broccoli – items that have fiber, vitamins, and enzymes built right in.
Q. What does “eating a rainbow” of fruits and vegetables really mean?
A. This is simply an easy way of remembering to get as much color variety in your diet as possible to maximize your intake of a broad range of nutrients. The colors of fruits and vegetables are often a tangible clue to the unique vitamins and other healthy substances they contain. Getting a variety of colors, therefore, means getting a variety of the essential nutrients your body needs to stay healthy and strong.
Enjoying the Rainbow: Fruit and Vegetable Benefits:
Q. Can you tell me a little more about the healthy components of fruits and vegetables?
Let’s take a look at some of the most well-studied and important nutrients:
Quercetin is found in apples, onions and citrus fruits (also is hawthorn and other berries and apple-related fruits usually used in traditional herbal remedies and modern supplements). It prevents LSL cholesterol oxidation and helps the body cope with allergens and other lung and breathing problems.
Clinical studies show that quercetin’s main points of absorption in the body appear to be in the small intestine – about 50%. The rest – at least 47% is metabolized by the colonic micro flora – the beneficial bacteria such as Lactobacillus acidophilus and Bifidobacterium longum. You may consider adding these beneficial bacteria (found in yogurt) either through the diet or a supplemental form.
Ellagic Acid is a component of ellagitannins – dietary polyphenols with antioxidant (and possibly anticancer) properties. Polyphenols are the basic building blocks of many plant-based antioxidants. More complex phenolic compounds, such as flavonoids are created from these molecules.
Ellagic acid is found in many fruits and foods, namely raspberries, strawberries, pomegranates, and walnuts. Clinical studies suggest that ellagitannins and ellagic acid act as antioxidants and anticarcinogens in the gastrointestinal tract.
Ellagitannins are durable antioxidants, and happily, they do not appear to be diminished by processing, like freezing. This means the benefits are still strong, even in frozen packs of raspberries or strawberries, or some of the better multi-ingredient supplement drink mixes.
In scientific studies, ellagic acid also showed an anti-proliferative effect on cancer cells, decreasing their ATP (adenosine triphosphate) production. ATP is the molecule that provides the primary energy source for the cells in our bodies. In a sense, ellagic acid seems to deprive cancer cells of their fuel.
Beta-Carotene: Probably the best-known of the carotenoids, beta-carotene is converted by the body into vitamin A. Many vegetables, especially orange and yellow varieties, are rich in this nutrient. Think summer squash, yams and of course, carrots.
Beta-carotene has long been associated with better eyesight, but it has other benefits, too. In a scientific study, beta-carotene decreased cholesterol levels in the liver by 44% and reduces liver triglycerides by 40%.
Lycopene is a carotenoid mostly found in tomatoes, but also in smaller amounts in watermelon and other fruits. Clinical studies have shown that lycopene consumption may decrease the risk of prostate cancer. In fact, high intakes of lycopene are associated with a 30% to 40% reduced risk. And, as good as beta-carotene is, its cousin, lycopene, seems to be an even stronger nutrient, protecting not just against prostate cancer, but heart disease as well.
Lutein is found in many fruits and vegetables, including blueberries and members of the squash family. Lutein is important for healthy eyes, and in fact it is found in high concentrations naturally in the macular region of the retina – where we see fine detail. It is one of the only carotenoids, along with its close sibling zeaxanthin, that is found in the macula and lens of the eye.
Lutein also supports your heart, too. In a scientific study, lutein reduced atherosclerotic lesion size by 43%. In other words, high intakes of lutein may actually help prevent coronary artery disease!
Interestingly, as is the case with lycopene, cooking or processing foods with lutein may actually make it more easily absorbed.
In clinical studies, men with high intakes of lutein (and its close cousin, zeaxanthin, found in broccoli and spinach) had a 19% lower risk of cataract, and women had a 22% decreased risk, compared to those whose lutein intakes were much lower.
Vitamin C: One of the best-known nutrients out there, vitamin C keeps our immune system strong; speeds wound healing, and promote strong muscles and joints. A free-radical fighter, vitamin C prevents oxidative damage to tissues, builds strength in collagen and connective tissue, and even reduces joint pain.
Sources of vitamin C are scattered throughout the spectrum of fruits and vegetables.
Potassium: Most Americans are deficient in potassium. For the most part, it’s hard to get too much of this valuable mineral. Potassium does great things for our hearts. Higher intakes of dietary potassium from fruits and vegetables have been found in clinical research to lower blood pressure in only 4 weeks.
Many researchers believe that the typical American diet has led to a state of chronic, low-grade acidosis – too much acid in the body. Potassium helps change pH balance to a more alkaline environment in the body and increases bone density.
This was proven in the long-running Framingham Heart Study which showed that dietary potassium, (along with magnesium and fruit and vegetable intake) provided greater bone density in older individuals.
Fiber is another food component many just don’t get enough of – especially if they’re eating a “typical American diet.” Fruits, vegetables and whole grains are excellent sources of fiber. However, fiber from a good fruits and vegetable drink mix should be derived from inulin and chicory root. This soluble fiber source not only adds to the overall amount of fiber you need (25 to 38 grams a day), but also provides a nice “nesting ground” for the beneficial bacteria that populate the intestines. And, even though some fiber has a bad rap for inhibiting mineral absorption, inulin and chicory root are “bone building” fibers – they actually help the body absorb calcium.
Flavonoids are an overarching term that encompasses flavonols, anthocyanidins, and flavones, isoflavones, proanthocyanidins, Quercetin and more. They are almost everywhere: in fruits, vegetables, grains, herbs, nuts and seeds – even in the coffee, wine and tea we drink. Flavonoids are responsible for the colors in the skins of fruits and the leaves of trees and other plants.
Flavonoids have many health benefits. They can help stop the growth of tumor cells and are potent antioxidants. Additionally, flavonoids have also been studied for their ability to reduce inflammation.
Anthocyanins: High on the list of important “visible” nutrients are anthocyanins. They color fruits and vegetables blue and red.
Anthocyanins are members of this extended family of nutmeats, the flavonoids. Typically found in high amounts in berries, anthocyanins are readily absorbed in the stomach and small intestine.
As antioxidants, anthocyanins dive deep into cell membranes, protecting them from damage. IT may be one reason why the anthocyanins from blueberries are considered such an important component in battling neuronal decline, like Alzheimer’s. Blackberries, raspberries, and strawberries are also excellent sources of this flavonoids group.
SDG lignans, (short for secoisolariciresinol diglucoside) are polyphenolic components of flaxseed, pumpkin and other herbal sources. Much of the recent research surrounding lignans has focused on flaxseed. In scientific and clinical studies, lignans from flaxseed support hormonal balance and may have cancer-preventing abilities. In fact, in one study, flaxseed lignans reduced metastatic lung tumor by 82% compared to controls.
The lignans in pumpkin seed, also considered a major source, target 5-alpha reductase activity.
This enzyme catalyzes the conversion of testosterone into the more potent dihydrotestosterone (DHT). DHT, like testosterone, is a steroid hormone or androgen. Androgens are responsible for the development and maintenance of masculine sex characteristics in both men and women. Excess levels of DHT can cause serious problems with prostate or bladder health. That’s why modulation of the 5-alpha reductase enzyme is so important – it helps maintain healthy testosterone and DHT levels. By balancing the levels of these key hormones, pumpkin seed lignans provide protection for prostate and bladder cells.
In addition, pumpkin seed has been shown to modulate the enzyme aromatase. Aromatase is present in the estrogen-producing cells of the adrenal glands, ovaries, testicles, adipose tissue, and brain. Aromatase converts testosterone, an androgen, into estradiol, and estrogen.
Inhibition of the aromatase conversion can help maintain a balance of healthy testosterone levels in women, which has been shown to strengthen pelvic muscles and reduce incidence of incontinence.
In fact, a clinical study, involving a pumpkin extract in conjunction with soy, resulted in significant support for bladder health. After two weeks of supplementation, 23 of the 39 postmenopausal women enrolled in the study showed great improvement in urinary frequency and sleep. By the end of the six week study, 74.4 percent of participants found pumpkin extract safely and significantly improved “nocturnia,” that is, the need to urinate frequently at night. For individuals with 2 to 4 episodes of nocturnia prior to the stud, and 81.8% improvement was seen – also showing great improvement in sleep quality. After all, if you don’t have to wake up every couple of hours to go to the bathroom you’re bound to get better sleep.
Beta glucan: Mushrooms are intense immune-boosting powerhouses due to their beta-glucan content. Three well-studied power-house mushrooms that contribute beta glucan to the diet include maitake, reishi and shiitake.
The most significant constituents of mushrooms are long chain polysaccharides (molecules formed from many sugar units) known as beta-glucan. These huge molecules act as immunoregualtors in the human body, helping to stabilize and balance the immune system.
This includes specific support of white blood cells, or lymphocytes, the primary cells of the immune system. Lymphocytes fall broadly into three categories: T cells, B cells, and natural killer (NK) cells.
In one clinical study, 165 patients with various types of advanced cancer were given maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, and 62% of lung cancer patients. Plus, when maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.
In another clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.
And, in a scientific study of human breast cancer and myeloma cancer and myeloma cancer cell lines, shiitake compounds provided a 51% antiproliferative effect on the cells – inducing “apoptosis’ – the programmed cell death that should occur naturally.
While beta-glucan are distributed throughout the mushroom body, the beta-glucan concentrations are significantly higher in the mycelium – the interwoven fibers or filaments that make up the “feeding structure” of the mushroom.
Bioflavonoids are commonly found in bright yellow citrus fruits, including lemons, limes and oranges. They are responsible for the bright pigment found in the skin of the fruit, and are considered a “companion” to vitamin C, seeming to extend the value of the nutrient within the body.
Hesperidin is just one of the valuable bioflavonoids found in citrus. Hesperidin appears to lower cholesterol levels, as well as support joint collagen in examples of rheumatoid arthritis.
Epigallocatechin gallate (EGCG):
Polyphenols, most notably EGCG, or epigallocatechin gallate, are well-studied and powerful components of tea. EGCG has been shown to reduce colon and breast cancer risk. Green tea also boosts the immune system and encourages T-cell formation – part of the front-line defense of our bodies against sickness and disease.
Q. I’ve been seeing articles about fruits, vegetables and supplements touting “high ORAC value.” What does this mean?
ORAC is an acronym for Oxygen Radical Absorption Capacity, and is simply a measurement of antioxidant activity of nutrients. Oxygen radicals, or free radicals, are unstable molecules. They grab electrons from other cells to use for themselves, and in the process can damage them. It is believed that free radical activity plays a role in the development of many diseases such as heart disease and cancer, and also plays a role in aging.
Antioxidants help prevent this damage by “loaning out” extra electrons to stabilize free radicals/ Consider any fruit or vegetable with a high ORAC rating as having a lot of “antioxidant power.”
I know I should eat more fruits and vegetables, but it just seems so hard to get five servings a day.
The number one excuse I hear for not buying frits and veggies is that “fruits and vegetables are too expensive.” But are they really? Certainly, fresh foods that aren’t in season and have to be shipped a distance can be a bit pricey. If anyone added up how much spend on fast food, or prepackaged or processed snacks, it would probably be shocking.
Luckily, there are many ways to get your “Daily 5”. For instance, frozen fruits and veggies retain much of their nutrient profile. They can be an excellent alternative when certain foods are out of season. So too, are fruit and vegetable drink mixes – excellent supplemental sources of some of the nutrients our bodies need most.
More recently, the American
Of course, for people not accustomed to the fiber in fruits and veggies, there is some reason to think it’ll increase gas. When cell walls break down, and fiber passes through the system, it can create flatulence. Folks who eat fruits and vegetables every day generally don’t have this problem. Their systems are already accustomed to it.
For those just starting out on a better diet, however, start slowly – it helps your body adapt. Cooking vegetables can help, too, because it begins breaking down the cell walls early on.
One thing is certain, however. The “Typical American Diet” and good health are mutually exclusive. The increase in type 2 diabetes, heart disease, high cholesterol, and hypertension all point to the abuse our bodies suffer by eating diets high in fatty meats, processed sugars, and refined grains.
Q. Can I just drink fruit and vegetables drinks in place of 5 servings of fruits and vegetables?
Green drinks and fruit and vegetable drink mixes aren’t meant to replace whole foods, but they can be an excellent substitute when you’re rushed or traveling or just trying to fill everyday nutritional gaps. Their whole food ingredients absorb very easily and gently in the gut, and many of these drink mixes contain healthy doses of fiber, too.
Green drink mixes and food-based drink mixes combine many colorful fruits and vegetables and sometimes grasses in a healthy, mixable supplement assortment. While there have been many advancements in the field of green drinks, there are only a few that take the primary reason we eat into consideration: taste!
Happily, there are some companies out there with great-tasting drink mixes that also formulate based on the color concept, ensuring you get the broadest assortment of nutrients from a full range of fruit and vegetable colors to promote optimal health.
High-quality fruit and vegetable drink mixes offer the best from nature’s color wheel in a convenient and great-tasting supplement. So, the next tie you feel like taking a coffee break – try a fruit and veggie break instead. Your body and spirit will thank you.
Triphala Fact Sheet
December 08, 2005 04:09 PM
Triphala Fact SheetNeil E. Levin, CCN, DANLA 6/30/05
LIKELY USES: Antioxidant Colon Cleansing, Detoxifying, Digestive, Liver and bile health
KEY INGREDIENTS: Triphala 500 mg, in a combination of fruit powders and extracts
MAIN PRODUCT FEATURES: Triphala is a combination of three fruits (Harada, Amla, and Behada) that has been used in Ayurvedic herbalism for thousands of years. Triphala's historical use as a digestive cleanser and tonifier has been backed up with numerous modern scientific studies demonstrating the positive effects of its component herbs on the gastrointestinal tract. In addition, Triphala has been shown to be a potent antioxidant, protecting cells against the damaging effects of free radicals. May help to dispel worms. Mild-acting internal cleansing; supports liver and gastrointestinal function
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW offers the first - and only - Triphala supplement to combine the fruit powders (400 mg) with the extracts (100 mg) of the fruits (doses given per tablet, there are three tablets per serving). Authorities like Dr. Andrew Weil consider Triphala to be a superior bowel tonic, rather than a laxative, with its benefits increasing over time. Laxatives typically are habit-forming and do not enhance normal body elimination of wastes; this is not the case with (moderate doses of) Triphala. This formula is suitable for vegetarians and is offered in tablet form.
SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every three tablets provide 1,200 mg. (1.2 gram) Triphala powder and 300 mg. (0.30 gram) Triphala extract. Both the powder and the extract provide the three fruits in equal ratios, by weight. Take one to three servings per day, between meals.
COMPLEMENTARY PRODUCTS: Fiber sources (psyllium, pectin, etc.), Detox Support, Plant Enzymes, Virgin Coconut Oil, Dr. Verghese Liver Formula, Bentonite Powder, Probiotics (GR-8 Dophilus, 4x6 Acidophilus, etc.), Electrolytes (minerals) CAUTIONS: none
PRODUCT SPECIFIC: Contraindicated during pregnancy and lactation; avoid during menstruation; not appropriate for the very young or very old or the convalescent.
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.
Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
REFERENCES: Abraham S, Kumar MS, Sehgal PK, Nitish S, Jayakumar ND. Evaluation of the inhibitory effect of triphala on PMN-type matrix metalloproteinase (MMP-9). J Periodontol. 2005 Apr;76(4):497-502. PMID: 15857087 Al-Rehaily AJ, Al-Howiriny TA, Al-sohaiani MO, Rafatullah S. (2002) Gastroprotective effects of 'Amla" Emblica officinalis on in vivo test models in rats. Phytomedicine 9(6):515-522.
Arora S, Kaur K, Kaur S. Indian medicinal plants as a reservoir of protective phytochemicals. Teratog Carcinog Mutagen. 2003;Suppl 1:295-300. PMID: 12616620 Jagetia GC, Baliga MS, Malagi KJ, Sethukumar Kamath M. The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation. Phytomedicine. 2002 Mar;9(2):99-108. PMID: 11995956 Jagetia GC, Malagi KJ, Baliga MS, Venkatesh P, Veruva RR (2003) Triphala, an Ayurvedic Rasayana Drug, Protects Mice Against Radiation-Induced Lethality by Free-Radical Scavenging. J Alt Complement Med 10(6):971-978. Jagetia GC, Rao Sk,, Baliga MS, Babu K (2004) The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary study. Phytother Res 18(7):561-565.
Kaur S, Michael H, Arora S, Harkonen PL, Kumar S. The in vitro cytotoxic and apoptotic activity of Triphala--an Indian herbal drug. J Ethnopharmacol. 2005 Feb 10;97(1):15-20. Epub 2004 Dec 25. PMID: 15652269 Kaur S, Arora S, Kaur K, Kumar S. The in vitro antimutagenic activity of Triphala--an Indian herbal drug. Food Chem Toxicol. 2002 Apr;40(4):527-34. PMID: 11893411 Sabu MC, Kuttan R (2002) Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol 81:155-160. Sairam K, Rao CV, Dora M, Babu K, Kumar V, Agrawal VK, Goel RK (2002) Antiulcerogenic effect of methanolic extract of Emblica Officinals: an experimental study. J Ethnopharmacol 82:1-9. Sandhya T, Lathika KM, Pandey BN, Mishra KP. Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drug. Cancer Lett. 2005 May 14; [Epub ahead of print] PMID: 15899544 Tamhane MD, Thorat SP, Rege NN, Dahanukar SA (1997) Effect of oral administration of Terminalia chebula on gastric emptying: an Experimental study. J Postgrad Med 43(1):12-13. Vani T, Rajani M, Sarkar S, and Shishoo CJ. Antioxidant Properties of the Ayurvedic Formulation Triphala and its Constituents. International Journal of Pharmacognosy Vol 35, No. 5, 1997:313-3
Celadrin and MSM Fact Sheet
December 07, 2005 01:24 PM
Celadrin and MSM Fact SheetNeil E. Levin, CCN, DANLA Certified Clinical Nutritionist, Diplomate in Advanced Nutritional Laboratory Assessment Revised 11/10/05
LIKELY USERS: People lacking flexibility or mobility; People wanting temporary control of aches and pains; People wanting to reduce pro-inflammatory body chemicals. KEY INGREDIENT(S): Celadrin® powder 500 mg. Provides 350 mg. of actual EFAC (esterified fatty acid carbons). This is a proprietary blend of Esterified Fatty Acid Carbons of Myristate, Myristoleate, Laurate, Oleate, Palmitate and Palmitoleate in a base of tapioca and silica.
MSM 100 mg.
MAIN PRODUCT FEATURES: CELADRIN® is an all-natural proprietary matrix of esterified (cetylated) fatty acid carbons (EFAC) derived from tallow of USA-raised cattle. This product is developed through a proprietary process of esterifying oil & has been clinically tested. Celadrin promotes joint health by improving flexibility, pain management and mobility. The myristoleic acids and the cetylated forms may alter the 5-LOX enzyme and change the leukotriene production, inhibiting inflammatory compounds.
Celadrin® may offer some noticeable benefits faster than other substances, like glucosamine and chondroitin. Though it is not a substitute for these important tissue-building nutrients. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: MSM has synergistic abilities to reduce certain substances in the body which may affect the inflammatory process.
Contains Cetyl Myristoleate (CM, CMO), but in a patented blend of other fatty acid carbons. This product (Celadrin ®) has its own clinical studies showing safety and efficacy.
Also will be available in a softgel of the same potency (350 mg. of EFAC) as of December 2005 (product 3017, 90 softgels)
SERVING SIZE & HOW TO TAKE IT: Three capsules a day, preferably with meals.
POSSIBLE SYNERGISTS: Glucosamine, Chondroitin, MSM, Joint Support Products, Manganese, Vitamin C, other Antioxidants
GENERAL: Pregnant and lactating women, and people using prescription drugs, should consult their physician before taking any dietary supplement.
This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients.
When taking any new dietary supplement, use common sense and cautiously increase to the full-recommended dose over time, looking for possible side effects. Repeat this process for each new supplement that you start to use.
REFERENCES: 1. J Rheumatol. 2002 Aug;29(8):1708-12. Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis. Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R.
Immune Renew Fact Sheet
December 07, 2005 01:07 PM
Immune Renew Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05
LIKELY USERS: Everyone seeking a healthy immune system; People on low carb diets or non-whole grain diets that are lacking dietary beta-glucans
KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg). Proprietary blend of 8 organically grown “medicinal mushrooms” (200 mg)
MAIN PRODUCT FEATURES: Vegetarian formula. Polysaccharides in these US-grown mushrooms grown on organic brown rice include 1,3 Beta-glucans and terpenoids. Beta-glucans may stimulate the immune system in different ways. Triterpenoids may act as mild anticoagulants. Each mushroom may have a different effect; for example, one may stimulate T-cells and another Natural Killer cells, aiding in immune defense. Mushrooms have reported beneficial effects on liver health and promoting normal cell growth.
ADDITIONAL PRODUCT INFORMATION: Some extracts from these kinds of mushrooms have been used medicinally in Japan and China. The mushrooms include Turkey Tail, Sun Mushrooms, Maitake, Cordyceps, Phellinus, Lion’s Mane, Reishi and Shiitake. The astragalus extract also contains naturally occurring astragalosides. Mushrooms may help maintain normal cholesterol and triglyceride levels
SERVING SIZE & HOW TO TAKE IT: For everyday use take one or two caps per day, either with meals or on an empty stomach.
COMPLEMENTARY PRODUCTS: Vitamin C to break down beta-glucan structures for better absorption, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and antioxidants
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease. Use with caution if using anticoagulants or blood pressure medication, as these mushrooms may have mildly synergistic effects to those drugs. Do not use if you have mold or mushroom allergies (or any sensitivities to mushrooms, cheese, etc.), which can potentially result in hives, rashes, breathing difficulties (including dry mouth or throat), stomach distress, diarrhea, or any other unusual side effect.
This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995
Cancer fighter found in broccoli
July 27, 2005 10:05 AM
Remember when your mother told you to eat your broccoli? Research shows that mother just might know best. In a recently published paper, Dr. Paul Talalay of Johns Hopkins University School of Medicine indicates that studies in his lab show broccoli is rich in sulforaphane, a chemical that works as a powerful anti-cancer compound in laboratory mice.
Other studies have shown that a diet rich in cruciferous vegetables—which include broccoli, Brussels sprouts, cabbage, cauliflower, and others— can significantly reduce the risk of cancer of the bowel, stomach and breast. Until now, the exact reasons why these vegetables had this effect we re not very clear. Until now, that is. According to Dr. Talalay, it appears that at least one anticancer ingredient in the vegetables is sulforaphane, which essentially causes cells to expel cancer-causing toxins. In addition, Dr. Talahay said that this study was the first to show that a high-potency compound isolated from vegetables could accelerate the detoxification process in cells.
The published report outlines how the research team isolated sulforaphane from broccoli, then fed it to a group of mice. When cells in the mice we re examined after five days, the scientists found that the chemical had triggered enzymes known to neutralize carcinogens within cells. Be yond this study, Dr. Talalay indicates that research will shift to the long-term effects of the chemical. “Our prediction is that sulforaphane will block tumor formation in animals and presumably in man.” In earlier studies, Dr. Talalay and others have shown that certain proteins in cells, called phase I enzymes, can take innocent chemicals and turn them into cancer-causing agents.
Other proteins, called phase 2 enzymes, tend to block formation of carcinogens. According to the study, sulforaphane is a potent activator of phase 2 enzymes. The Hopkins researchers will conduct tests to determine how much broccoli must be consumed to establish an effective anti-cancer level of sulforaphane in cells.
Over a decade of research has been done on cruciferous vegetables and there are large databases that confirm that cruciferous vegetables substantially reduce the risk of disease, specifically cancer. Studies show substances in these vegetables that have anti-cancer properties which cause the body to speed up production of enzymes, therefore being capable of neutralizing cancer agents. The studies also show these pre vent damage to our DNA and slow the aging process. In women, metabolic processes are regulated which eliminate the bad (and maintain the good) estrogen, therefore substantially reduce the risk of breast cancer. Shortly after the NCI study was released, John Hopkins School of Medicine revealed similar studies.
CANCER/TUMORS AND ST. JOHN'S WORT
July 15, 2005 09:31 AM
St. John’s wort, and more specifically, hypericin, has an outstanding ability to work favorably at the cell level against normally destructive invaders like viruses and bacterias. But these are not the only destructive agents that are being targeted by researchers in Hypericum research. Hypericin has been shown in various recent studies to work very effectively against cancerous cells and tumors of varying kinds. The April 1996 issue of Laryngyscope reported that hypericin is showing great potential in targeting human cancer growths through what is called “phototargeting,” a process that uses laser activation of hypericin, along with chemotherapy, for improved results in inhibiting the growth of cancerous cells. The study states, These results show that hypericin is a sensitive agent for phototherapy of human cancer cells in vitro and indicate that this drug may be useful for tumor targeting via minimally invasive imaging-guided laser fiber optics.22
Another recent study commented on the use of hypericin in treating human cancer cells, saying that “the nucleus of the cell . . . is the target for the toxic action of hypericin.” The study pointed out that the compound is well distributed throughout the cells, indicating that its value as an anticancer agent remains high.23
Yet another study points to the photodynamic qualities of hypericin in combating cancerous cells. The study’s results suggest that hypericin “has considerable potential for use as a sensitizer in the PDT [photodynamic therapy] of cancer.” And when hypericin was used in conjunction with other “scavenging” agents, its inhibitory abilities were greatly enhanced. Again, with such promising results from clinical studies, St. John’s wort (and hypericin) is perhaps opening the way to curing one of our most devastating diseases, cancer. Further research could quickly finalize a cure.
ST. JOHN’S WORT AND AIDS/HIV
July 15, 2005 09:28 AM
ST. JOHN’S WORT AND AIDS/HIV
In 1991, some of the first work focusing on St. John’s wort’s effects on AIDS and the HIV virus began. Science magazine reported on the first study using the isolated hypericin, a key compound in Hypericum.16 Fred Valentine and Howard Hochster, researchers at New York University Medical Center, began one of the first studies looking at how hypericin can help uninfected T-cells from being infected with the AIDS virus in a cell culture. Their focus was on hypericin because it is a virucidal agent, meaning it can precisely target new virus particles and prevent them from infecting other cells.
The only two drugs at that time approved for treating HIV infection—AZT and ddI—work by interfering with the key viral enzyme, reverse transcriptase. Since hypericin works more effectively than many drugs in regards to the reverse transcriptase phase, and since many animal tests have shown that it has low toxicity at therapeutic doses, researchers (including Valentine and Hochster) began these studies largely hoping that not only would hypericin work on its own, but that it would have a sort of synergistic effect when used with either AZT or ddI. 17
Additional studies are pointing to St. John’s wort, and more so, hypericin, as having great potential in treating HIV. Acosta and Fletcher recently detailed the processes in which the human immunodeficiency virus works to infect human cells, and point out that hypericin is at least somewhat effective in inhibiting the four main phases of virus “growth”— binding and entry, reverse transcriptase, transcription and translation, and viral maturation and budding (the researchers note that hypericin is especially effective in binding and entry, the first phase.) This denotes that hypericin could eventually have special importance in completely stifling the development of the growth of any virus, and most importantly, that of the HIV virus.18
Another study assessing the use and attitudes of HIV sufferers concerning the use of more alternative treatments for the virus as opposed to clinical drug therapies showed both an extensive use of unconventional therapies and a very favorable response to using the alternative treatments, which, of course, St. John’s wort was among. “Participants at all sites expressed positive views upon increasing unconventional remedies.”19 The fact is that the world of synthetic medicines has been basically ineffective in not only treating and relieving the symptoms of AIDS, but also in finding a cure for the dreaded disease. Sufferers are giving alternative therapies a try, and the results are very promising.
A 1995 review appearing in Photochemisty-Photobiology treated the photodynamic properties of both hypericin and the structurally related hypocrellins for their anticancer and antiviral properties (especially the anti-human immunodeficiency virus). This article states that the promising anticancer and antiviral results obtained both in vitro and in vivo [in differing studies] have led to intensive investigation into their photo-physical and photochemical processes, especially kinetic studies of their intramolecular proton transfer . . . The biomedical advances of hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericin.20
Another study published in the September 1994 issue of Photochemistry-Photobiology gave hypericin the upper hand over the hypocrellins in treating HIV. Just one more vote in favor of promoting the use of St. John’s wort, and more specifically, hypericin, for use in treating HIV and in overall clinical medicine.
July 14, 2005 10:46 PM
One of the reasons St. John’s wort is attracting so much interest is because of one of its compounds, hypericin. The journal Photochemistry-Photobiology recently published a review of hypericins and the structurally related hypocrellins, giving a favorable outline of the various recent breakthroughs in medicine using these two compounds. The review states, Hypocrellins and hypericins, structurally related plant pigments isolated from Hypocrella bambuase and Hypericum respectively, are known photodynamic agents. This review summarizes certain significant advances in the phtotophysics, photochemistry and photobiology of these pigments in the last two years and discusses their prospects as novel therapeutic and diagnostic agents in the future . . . In particular, substantial progress has been made in both anticancer and antiviral applications (especially anti-human immunodeficiency virus). . . . The biomedical advances of hypocrellins and hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericins.2 The compound hypericin was isolated from St. John’s wort in 1942 and has been used as an anti-depressant and mood stabilizer for emotionally and mentally disturbed people.
Among its many beneficial qualities is that of increasing blood flow to stressed tissue, thereby having a tranquilizing effect. It also reduces the fragility of capillaries and enhances uterine muscle tone because of its ability to increase blood flow.3 It is this compound that is being extensively researched for its possible therapeutic properties for a variety of diseases, mainly depression, AIDS and other viruses, cancer and sleep disorders.
Extensive research has been done, especially recently, to determine exactly how hypericin works in treating these and other disorders. Nearly all the researchers are saying the same thing—that Hypericum (and specifically hypericin) promises significant value to the medical world in overcoming these serious disorders. The following sections discuss the various disorders that are being researched in conjunction with Hypericum/ hypericin therapy.
HAWAIIAN NONI (Morinda citrifolia)
July 11, 2005 08:50 PM
In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:
Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.
The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.
Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.
Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.
discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.
ROOT AND ROOT BARK
Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.
Body Systems Targeted
The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.
Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.
Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .
NONI: ITS USE AND HISTORY
Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .
Wonder Herb of Island Folk Healers
Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.
Noni’s Medical Reputation
Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.
A Timely Reemer gence
Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.
TRADITIONAL USES OF NONI
Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15
decoctions to stimulate delayed menst ruation.
XERONINE: THE SECRET OF NONI?
One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .
Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18
How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.
MODERN APPLICATIONS OF NONI
Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.
Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.
xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.
A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21
In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.
with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.
The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.
The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.
The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.
While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.
A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29
Skin Healing Agent
One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.
burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30
The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.
Complementary Agents of Noni
PrimaryApplications of Noni
Ginsengs - Energy Tonics For Today's Hectic Lifestyles
June 30, 2005 09:34 AM
Ginsengs By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt
What's the difference between Chinese (white root), Chinese (red root), Eleuthero and American Ginsengs? Which one is best for me? There are actually many different "ginsengs." We will discuss those mentioned above since they are the most widely available. All of these Ginsengs are considered to be potent adaptogens, which means that they are: 1) harmless to the body 2) non-specific in their actions 3) have balancing or normalizing effects. An adaptogen helps the body adapt to stress - both mental and physical. It is in this area that ginseng excels.
Chinese Ginseng (Panax ginseng) is what most of us think of when Ginseng is mentioned. It is indigenous to the forests of northeast China, Manchuria and Korea. Red Ginseng is often referred to as "Korean" Ginseng. In traditional Chinese Medicine Ginseng is used to tonify the "Chi" (vital energy or life energy force). Modern scientific studies indicate Panax Ginseng stimulates the immune system, has antifatigue, antistress, antitumor, anticancer and anti-aging properties, balances blood sugar levels, enhances mental performance and memory, lowers cholesterol, strengthens the heart muscle and protects against radiation damage. Panax ginseng has had a notorious reputation as a sexual rejuvenator which studies give some credence to; albeit not to the degree of its reputation. Ginseng "overuse syndrome", although rare, is characterized by irritability, insomnia and rapid heart beat, and is associated with using too much Chinese Ginseng, especially by healthy, active men.
American Ginseng (Panax quinquefolium) is indigenous to the eastern woodlands ranging from Georgia to Quebec and was used by many Native Americans. Jesuit Priests were reported to be trading American Ginseng to the Chinese as early as 1718. Ironically, American Ginseng is highly sought after in China, while Americans chase after Chinese ginseng. While having much the same adaptogenic qualities of Chinese Ginseng, American Ginseng is believed to have a more "yin" or cooler nature. What this means is that American Ginseng is excellent for the high-paced, stressed, not enough time culture that we live in. While still energizing the body, American Ginseng calms the central nervous system, quiets the brain and lowers blood pressure. Also, because of its more "yin" nature, it is generally better to use on a day-to-day, long term basis than Chinese Ginseng. American Ginseng is one of the best tonics for all-around health and vitality, particularly well suited for the hectic world we've created.
Eleutherococcus senticosus (known as Siberian Ginseng in Herbs of Commerce) is native to Siberia, Japan, Korea and China. Although not a "true ginseng", this variety is most highly prized. Eleuthero was traditionally used to promote longevity and general health. Many herbalists prefer Eluthero for helping with women's health issues. It is particularly useful with depression associated with PMS and menopause. Research, mostly from Russia, confirms this herb's ability to increase mental and physical performance, stimulate the immune system, increase phagocytosis (movement of white blood cells) promote circulation and enhance the benefits of medical radiation treatments while lessening its negative side-effects. (The dosage used in one Russian study was 4 milliliters in the morning and 2 milliliters at night.)
Which Ginseng is Right For Me Here's a simple guide for deciding which Ginseng to use. Chinese Ginseng is best suited as a tonic 1)for the fragile and weak 2) during convalescence, and/or 3) to support the immune system. American Ginseng is for regular daily use, specially suited for energetic personality types. Eleuthero is excellent for endurance and stamina, and well suited for athletes as well as for women's issues. If you're still confused, try Balanced Ginseng™ (alcohol-free) a high-powered liquid herbal extract supplement that blends several varieties of Ginsengs together to assure balanced tonic action.
It is important in purchasing Ginseng products to buy from a company you trust and one that has the technical capabilities to test and guarantee quality and activity. Unfortunately, the Ginseng market is prone to both adulteration and poor activity levels. Nature's Answer®, with its full pharmaceutical level in-house laboratory and years of experience, is proud to offer a variety of the finest quality of Ginseng formulations available in either liquid (alcohol-free or organic alcohol) or encapsulated (standardized or single) forms. The company also offers the herb in unique, proprietary blends. All products are Unconditionally Guaranteed.
CHOLESTEROL RESCUE - Maintain Your Cholesterol Wellness
June 29, 2005 01:48 PM
You live in a fat-drenched, fast food world, propped up by diets loaded with processed foods that stimulate your body to create excess bad cholesterol – or low-density lipoproteins (LDL). Your busy life is full of stress, and devoid of time for proper exercise. There are three ways to deal with cholesterol in the body, but a seemingly infinite number of lifestyle and hereditary elements that affect LDL levels. Is it any wonder you find yourself in danger of developing unwanted cholesterol levels? Source Naturals is devoted to helping you. So we developed CHOLESTEROL RESCUE as a comprehensive solution to help you keep cholesterol levels in the normal range. CHOLESTEROL RESCUE uses only natural ingredients, clinically researched to effectively maintain healthy cholesterol levels. It is scientifically formulated with the triple action of three ingredients that target the ways you can deal with your cholesterol concerns; combining the naturally occurring polymethoxylated flavone (PMF) and tocotrienol action of Sytrinol™ with the action of plant sterols. Research suggests that daily consumption of 800 mg of plant sterols, taken with food in two divided doses as part of a diet low in saturated fat and cholesterol, may reduce the risk of coronary heart disease. Source Naturals offers CHOLESTEROL RESCUE as part of our ongoing commitment to providing you with high quality natural supplements to support your healthy lifestyle.
Cholesterol & Your Body
On average, humans ingest approximately 300mg of cholesterol per day. Though an important part of a healthy body, a high level of cholesterol in the blood might be out of the normal range. Cholesterol is transported in your system by lipoproteins. There are two kinds of lipoproteins in your body, but the low-density lipoproteins, or LDL, are the major factors in developing unwanted cholesterol levels. If there are high levels of LDL circulating in your bloodstream, it can undergo oxidation by free radicals in the artery walls, which can then become trapped as imbalanced deposits. These deposits can build up, reducing critical blood-flow. CHOLESTEROL RESCUE has been specially developed to reduce LDL levels using two different methods: inhibiting the synthesis of cholesterol in the liver, and reducing the absorption of dietary cholesterol.
The Plant Sterol Effect
Sterols are an essential component of the cell membrane, and are produced by both plants and humans. While the most common sterol produced in humans is cholesterol, plants produce phytosterols, or plant sterols. Using a complex compound of plant sterols similar to cholesterol with only slight molecular differences, CHOLESTEROL RESCUE has been formulated to balance the amount of dietary cholesterol your body absorbs.
Plant sterols have long been known to inhibit the uptake of both dietary and bile-produced cholesterol in the intestines. The most plausible theory behind this is that, because of the similarity between plant sterols and cholesterol, the body cannot properly distinguish between the two during the absorption process, thereby displacing the uptake of cholesterol into your system. Research suggests that daily consumption of 800mg of plant sterols, taken with food in two divided doses as part of a diet low in saturated fat and cholesterol, may reduce the risk of coronary heart disease.
CHOLESTEROL RESCUE also contains SYTRINOL™, a proven natural alternative for maintaining cholesterol wellness. The patented blend of citrus polymethoxylated flavones (PMFs) and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, helping balance triglyceride production, and providing powerful antioxidant protection. The PMFs promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Tocotrienols help break down cholesterol building blocks, interfere with cholesterol production, and provide critical antioxidant protection. Because cholesterol becomes problematic when oxidized, the powerful antioxidant action of tocotrienols can help prevent the conditions that may affect your cardiovascular circulation.
Spearheading the Wellness Revolution in Cholesterol Defense
With so many ways to develop undesirable cholesterol levels in your body, you need to be proactive in maintaining your good health. In our on-going dedication to your wellness, and a commitment to delivering the benefits of our high quality supplements to the natural products marketplace, Source Naturals has produced a scientifically formulated blend of three effective ingredients in fighting unwanted cholesterol. Combining a comprehensive formula of allnatural components, clinically researched for promoting cardiovascular health, CHOLESTEROL RESCUE is available now at your local health food store.
SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...
June 29, 2005 09:44 AM
SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...
Maintaining your cardiovascular health is one of the best ways you can stay fit. That means working to keep your cholesterol levels within the normal range. And contrary to popular belief, the amount of cholesterol you consume in food is not the most important factor for regulating normal cholesterol levels. It is actually the liver’s imbalanced production of cholesterol that is much more critical for your cardiovascular health.
You can address the root cause of maintaining normal cholesterol levels today with Source Naturals SYTRINOL™. This patented blend of citrus polymethoxylated flavones and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, promoting balanced triglyceride (fat) production, and providing antioxidant protection. Source Naturals, an industry leader in many categories, introduces the science of SYTRINOL™ in the CHOLESTEROL RESCUE™ product family to support your better heart health today.
The Truth About Cholesterol
Cholesterol is a very confusing subject – our bodies require it but we can also get too much of it. Cholesterol is one type of the ring-shaped compounds called sterols. Other sterols include bile acids, sex hormones, adrenal hormones and vitamin D. Approximately 90% of the cholesterol in your body is in your cell membranes. The remaining 10% can be found in your blood and throughout your body.
Liver’s Over-Production of Cholesterol
When your body needs more cholesterol, your liver takes carbohydrates, proteins and fats (also called triglycerides) from your diet and converts them into cholesterol. The amount of cholesterol that you might consume from foods (in animal products such as eggs, milk, cheese and beef ) is minute compared to the amount of cholesterol produced by your liver. Thus, cholesterol from food isn’t as critical to your total cholesterol. But balancing the cholesterol produced by your liver is very critical to your total cholesterol and thus, your cardiovascular health.
Oxidized LDL Cholesterol
Despite the confusion, cholesterol is a vital component of good health that strengthens cell membranes and provides building blocks for hormones, bile and vitamin D production. However, there is one potential pathway where cholesterol can contribute to an imbalance. When cholesterol moves through the blood to individual cells, it can travel in groups such as lipoproteins, which also contain fats and proteins. When the cholesterol is moving through your blood in Low Density Lipoproteins (LDL) it can undergo oxidation by free radicals in the artery walls. Some medical experts theorize that the oxidized LDL cholesterol becomes trapped in the artery walls as imbalanced deposits instead of completing the journey to join cell membranes. These deposits can eventually reduce the size and function of the arteries, compromising blood flow. Thus, antioxidant protection, balanced triglyceride production, and normal cholesterol production by the liver can all be critically important to your good health. And SYTRINOL™ provides all of these benefits.
How SYTRINOL™ Supports Heart Health
SYTRINOL is a powerful scientifically formulated blend protected by U.S. patent numbers 6,251,400, 09/ 481724. It contains natural citrus polymethoxylated flavones (PMFs) and tocotrienols that go deep to address the root causes of cholesterol wellness.
Polymethoxylated flavones are types of polyphenolic compounds called flavonoids, which are the largest known category of phytonutrients. Health benefits of various flavonoids include antioxidant activity, immune system support, and cellular protection. The unique structure of polymethoxylated flavones, which naturally contain methyl groups paired with oxygen in key places, enables PMFs to interfere with cholesterol production. The citrus PMFs in SYTRINOL, such as tangeretin and sinensetin, promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting the activity of your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Since LDL cholesterol is made from cholesterol and triglycerides, decreasing your liver’s production of triglycerides will reduce the amount of those triglycerides available to form LDL cholesterol compounds.
Tocotrienols are compounds similar to vitamin E in structure and function. The tocotrienols in SYTRINOL increase degradation of cholesterol building blocks such as Apolipoprotein B, interfere with cholesterol production, and provide antioxidant protection. The tocotrienols in SYTRINOL are also especially protective antioxidants for LDL cholesterol compounds that have already been produced, helping to prevent the oxidized LDL cholesterol conditions that may affect your cardiovascular circulation.
SYTRINOL’s Proactive Synergy
SYTRINOL works so well because this natural blend of PMFs and tocotrienols works proactively, synergistically, and independently. In preliminary human research, SYTRINOL proactively supported balanced cholesterol and triglyceride production by the liver through the synergistic effects of the PMFs and tocotrienols. Furthermore, SYTRINOL promotes LDL cholesterol antioxidant protection.
The above information has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Other products work reactively to disable existing cholesterol and may only work in conjunction with diets. And because SYTRINOL works independently of diet, you can take it anytime.
Three Lifestyle Strategies for Cardiovascular Health
1. Exercise regularly to increase hearthealthy HDL cholesterol and lower blood triglycerides (fats).
2. Eat a healthy diet rich in fruits, vegetables, whole grains, and lean proteins to help maintain normal cholesterol and triglyceride levels.
3. Take the right supplements to promote your cardiovascular health. In preliminary clinical studies, the amino acid L-ARGININE supported healthy blood flow to the heart and body. GARLIC OIL helps to maintain healthy cholesterol levels and promotes healthy circulation. POLICOSANOL CHOLESTEROL COMPLEX, CHOLESRESPONSE™, CHOLESFIBER™, CHOLESTREX®, and GRAPEFRUIT PECTIN all help to support normal cholesterol levels. HEART RESPONSE™ and HEART SCIENCE™ are advanced formulas that address heart health. Additionally, you can get cardiovascular system supporting compounds such as folic acid, betacarotene, CoQ10, lipoic acid, ginkgo, grapeseed extract, hawthorn extract, magnesium, vitamin E, and many other nutrients in LIFE FORCE MULTIPLE™, Source Naturals’ best-selling multiple. There is a revolution underway in natural health consciousness, and your local health food store is at the forefront. You can benefit right now – long before word spreads to the general public – with the innovative heart nutrition of SYTRINOL, a CHOLESTEROL RESCUE™ product. SYTRINOL™ is a trademark of KGK Synergize exclusively licensed worldwide to SourceOne Global Partners.
June 23, 2005 11:50 AM
June 18, 2005 09:11 AM
Mushroom Miracles by Bert Hoffman Energy Times, April 12, 2004
Mention mushrooms and few people immediately recognize these humble fungi as important tools that can be used to boost well-being. More often, folks identify mushrooms as food with a peculiar appeal. But mushrooms' potential impact on health far surpasses their culinary reputation.
You don't have to stretch your imagination too far to understand why mushrooms have been much neglected in the modern, Western medical search for plants that can boost health.
Unable to make chlorophyll, often dependent on the kindness of other nutrient-producing organisms for their survival, these humble fungal denizens of dark, damp spaces seem to prefer an anonymous existence that is out of sight and out of the consciousness of the scientific mind.
However, mushrooms have now assumed a spot in the center of the research spotlight. Because of their potent content of natural chemicals that appear to have a strong influence on human health and well-being, during the past decade mushrooms have been the subjects of intensive studies on how they can be used to reduce the risk of cancer and to treat these diseases.
Appropriately, this recent round of research began in a place that has long revered these diminutive organisms: Japan. Japan and other Oriental countries have traditionally recognized the immense value of mushrooms as both food and medicine.
Food and Medicine
As an ancient Chinese saying notes, "food and medicine share a common origin." And one of the very earliest Chinese medical books, Shen Noug's Herbal (Shen Noug Pen Ts'ao Jing), first noted the extraordinary beneficial effects of eating mushrooms 2,000 years ago, back in the first century.
More recently, but still well ahead of Western medical experts, in 1575, Pen Ts'ao Kang Mu (a Chinese compendium of medicinal therapies), written by Li Shi Zhen, outlined the medical benefits of about 20 mushrooms.
Nowadays, modern researchers believe mushrooms' usefulness stems from the fact they contain a wealth of antioxidants. But these aren't just any antioxidants. Scientists think that some of these chemicals can potentially drop your risk of cancer, significantly lower blood pressure, help the body fight diabetes, offer protection for the liver, alleviate some of the ill effects of inflammation, lessen the chance of blood clots and help the body's immune system fend off viruses and other microbes. Quite a collection of benefits for these lowly beings!
The 10,000-Year Mushroom
Through the ages, the reishi mushroom (also known variously as the Mannetake, or 10,000-year mushroom, and the Immortality Mushroom) has been the most popular mushroom in Chinese, Korean and Japanese cultures. The reishi mushroom is frequently depicted in a wide variety of traditional Oriental artwork and even puts in an appearance in Chinese royal tapestries.
To some, reishi's power goes beyond the natural and include the supernatural. Originally grown on aging plum trees, reishi is also sufficiently well regarded to be employed by the Japanese as a good luck charm. But you don't have to believe in the supernatural to be superbly impressed with reishi. The beneficial natural substances in reishi include steroids, lactones, alkaloids, triterpenes and polysaccharides.
Of these chemicals, polysaccharides (complex chains of sugars) in particular have intrigued researchers looking into the way mushrooms help health. These polysaccharide macromolecules are very large (for molecules) and complex, a complexity that leads researchers to believe they are capable of conveying a huge amount of biological information that help the immune system stop cancer in its early stages. The differences in the benefits of various polysaccharides stems from their intriguing geometrical shapes.
Even though two distinctive polysaccharides may contain the same number of carbon, hydrogen and oxygen atoms, their three-dimensional differences-the way they are structured and branch off in different directions-can endow them with very different health benefits.
Though they all share a basic structure (usually, these molecules consist of a main chain of atoms with various side chains), the slight variations of the side chains changes their effects.
By deciphering the microscopic structures of these molecules, scientists think they are beginning to uncover which ones are most effective against cancer. For instance, in isolating a particularly useful polysaccharide called beta-D-glucan from reishi, researchers have found that this substance fights tumors in lab experiments (Chem Pharm Bull 1981; 29: 3611).
Meanwhile, beta-D-glucan and other extracts taken from the maitake mushroom have also been shown to possess powerful anti-cancer effects in lab experiments (Immunopharm Immunotox; 19:175).
In one instance, researchers in the laboratory who were trying out various substances on prostate cancer cells found that applying extracts of maitake results in a kind of programmed self-destruction (apoptosis) of these undesirable cancer cells (Molec Urol; 4:7). In addition, another substance known as maitake d-fraction has been shown to strongly fight cancer in lab animals-in one study, their liver cancer growths were reduced by up to 90% (Ann NY Acad of Sci; 833:204).
At the same time, research in China on people has demonstrated that maitake may help reduce tumors and alleviate the effects of leukemia (Alter Comp Ther 12/98; 420).
According to A.S. Daba and O.U. Ezeronye (Afr Jrnl Bio 12/03; 672), "Mushroom polysaccharides offer a lot of hope for cancer patients and sufferers of many devastating diseases.
" [These substances support]...a fundamental principle in Oriental medicine...[they help] regulate homeostasis of the whole body and... bring the diseased person [back] to his or her normal state."
The Activity of Active Hexose Correlated Compound Active Hexose Correlated Compound (AHCC), an extract taken from shiitake and other mushrooms, is a relatively new substance that is also being researched for its anti-cancer benefits.
Studies on AHCC began in Japan in the 1990s when scientists looked at how it could potentially help people recovering from liver cancer. In those tests, researchers found that giving people AHCC apparently helped them survive longer.
In the future, scientists feel certain that they will uncover even more anticancer uses for mushrooms and the chemicals they contain. A key advantage to these natural substances is their lack of side effects. For instance, in research on an anti-cancer chemical called lentinan, taken from shiitakes, investigators have found that less than one percent of people experience the kind of discomfort that make them discontinue treatment. (This chemical has been used to treat stomach cancer.)
But a long list of beneficial mushroom substances are probably still waiting to be discovered. More evidence of mushrooms' benefits: A study of mushroom workers in a part of Japan called the Nagano Prefecture found that these farmers enjoyed a significantly lower cancer rate than other inhabitants of that part of the country.
In the rest of Japan, about one in six hundred people dies of cancer. But that rate death rate drops to about one in a thousand for mushroom raisers who eat a diet heavy in mushrooms.
John Smith, PhD, from the University of Strath-Clyde, notes that "...increasing evidence [shows] mushrooms offer a remarkable array of medicinally important compounds that have yet to be evaluated by Western medical scientists." Mushrooms offer the best of both worlds: good health that tastes great.
The A Team
June 14, 2005 06:04 PM
The A Team
by Gregory Meade Energy Times, October 11, 2004
Want the A Team playing to improve your health? When you accumulate enough antioxidants to help you attack the molecular marauders out to mar your well-being, you improve your chances of avoiding illness.
Nowadays you hear plenty of talk about the benefits of antioxidant nutrients. Antioxidants are the ammunition the body uses to fight off internal damage. They offer the body the means to fight against disease but, at the same time, your body must be in the position to use them optimally. That means getting enough sleep, consistently exercising and avoiding overly processed foods. Those lifestyle habits allow your body to garner its resources and effectively implement antioxidants in its quest for well-being.
Your body has a love-hate relationship with oxidation: Can't live without it, often has trouble living with it. For instance, the production of energy in your cells requires oxidation. But the byproducts of that process, problematic molecules called free radicals, have to be chemically changed or eliminated to avoid the damage that results when they interact with other parts of the cell. Left unchecked, these molecular troublemakers can wreak havoc, oxidizing and punching holes in cell membranes and damaging other structures they contact. Antioxidant nutrients are used to defend against oxidation, quell these harmful destroyers and limit the potential harm they can cause.
For a quick glimpse of one of your basic antioxidant defenses, look in the mirror. The color in your eyes represents antioxidant protection against oxidative injury from the ultraviolet rays in sunlight. Sunlight's energy sets loose free radicals every time it enters the lenses in your eyes. Pigments absorb this radiation and, in most cases, render it harmless.
As part of your vision's defenses, two of the antioxidant pigments in your food, lutein and zeaxanthin, are deposited by your body in certain areas of your eyes-in a section called the macula as well as the lens (BJ Opthalmol 1998; 82:907-10).
Lutein and zeaxanthin are classified as carotenoids, chemical relatives of beta carotene, the antioxidant pigment that makes carrots orange, and lycopene, the anticancer red coloring found in tomatoes. These fat-soluble nutrients are also present in algae. In both your eyes and plants, these nutrients absorb the destructive ultraviolet rays that give birth to free radicals.
Studies show that consuming large amounts of these pigments lowers your risk of a common form of blindness called age-related macular degeneration (ARMD) and drops your chances of age-related cataracts. (More than 30 million people worldwide suffer from ARMD, and cataracts is the leading cause of blindness across the globe.)
When the sun's rays enter the eye, lutein and zeaxanthin absorb and filter out dangerous radiation before it can injure the macula. The macula is the central part of the retina that allows us to see very fine detail. Otherwise, over time, as the macula deteriorates, our vision worsens. In addition, some researchers believe these nutrients help lower your chances of cancer.
Lutein and zeaxanthin are found in spinach, Brussels sprouts, corn, collard greens, green beans, egg yolks, broccoli, cabbage, kale, lettuce, kiwi and honeydew melons. The petals of yellow flowers like marigolds and nettles are also rich in these antioxidant nutrients.
You can also increase your chances of better sight as you age by consuming sulphoraphane, an antioxidant found in broccoli. Researchers at Johns Hopkins University have found that sulphoraphane takes part in the body's efforts to shield eye cells from free radicals generated by ultraviolet light (Proc Natl Acad Sci 2004; 101(28):10446-51).
The researchers who performed this study believe that unlike the antioxidant nutrients vitamin C and natural vitamin E, sulphoraphane acts as an "indirect" antioxidant. That means that while those two vitamins are used by the body to directly defuse the harmful oxidative force of free radicals (and then must be replaced or regenerated in the cells), sulphoraphane acts indirectly, boosting the body's immunity defenses. Because of that indirect action, researchers point out, sulphoraphane lasts longer in the body and may produce a more profound, long-term antioxidant effect.
In other laboratory tests, researchers have discovered that sulphoraphane can kill Helicobacter pylori, a bacterium recognized 20 years ago as the cause of debilitating stomach ulcers and often-fatal stomach cancers (Proc Natl Acad of Sci 5/28/02). This research shows that sulphoraphane is even effective against antibiotic-resistant Helicobacter. Adding to its benefits, sulphoraphane can help kill bacteria both inside and outside stomach cells; when this bacteria hides inside of cells it is particularly difficult to fight.
" We've known for some time that sulforaphane had modest antibiotic activity," says Jed Fahey, a plant physiologist at Hopkins. "However, its potency against Helicobacter, even those strains resistant to conventional antibiotics, was a pleasant surprise."
Looking for Mr. Good Diet
For the biggest bang for your antioxidant buck, combine antioxidants with good lifestyle habits. A laboratory study of the heart-healthy effects of taking supplements of the antioxidant vitamins C and natural E along with L-arginine (an amino acid) found that exercise magnifies benefits (Proceedings of the National Academy of Sciences 5/24/04, online). The scientists who performed this study recommend exercise along with antioxidants to boost your nutritional advantage.
The box score shows that when playing with the A Team you've got the best chance of hitting an antioxidant home run.
Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
June 13, 2005 10:31 AM
Botanical Arsenal by Fred Thomas Energy Times, May 3, 1999
The complexities surrounding the various types of cancer stem from the variety of ways in which these diseases can wreak their havoc. Luckily, the equally complex world of plants contains novel compounds that can help our bodies fight off cancer's deadly progress.
Research into these botanical compounds is mushrooming. An example: The mighty maitake, a fungus with flair, alternately known as the king (it can grow as large as a basketball, worth its weight in silver to the ancient Japanese); the prince; the Hen of the Woods (it sticks out of from trees when it grows in the wild); and the dancing mushroom to those who leaped for joy when they found one growing in its native northeastern Japan.
Researchers today dub it with a new moniker: Herbal Heavyweight.
Mushroom with Potential
The maitake, with such other medicinal mushrooms as shiitake and reishi, historically has been eaten to promote general well-being and vitality. In the modern lab, however, scientists focus on the potent immune enhancing powers of maitake, which spotlight its cancer fighting potential.
Twenty years ago, maitake, Grifola frondosa, was an obscure, largely unavailable mushroom. A series of significant Japanese studies then catapulted it into prominence-and popularity.
Hiroaki Nanba, PhD, of the department of immunology at Kobe Women's College of Pharmacy on Kobe, Japan, and a leading international researcher on maitake, conducted the preliminary tests on the mushroom, demonstrating that it stimulates immune function and inhibits tumor growth.
In 1986, Dr. Nanba fed powdered maitake to mice injected with tumor cells; 86.3% displayed inhibited tumor growth.
Dr. Nanba and his colleagues went on to run additional mouse tests, finally reporting that this potent mushroom "directly activates various effector cells (macrophages, natural killer cells, killer T-cells, etc.) to attack tumor cells."
From then, maitake mushrooms were headed to fame as cancer ninjas.
Stoking The Immune Engine
Like other mushrooms, maitake is rich in complex polysaccharides, immunomodulators that successive tests after Dr. Nanba's have shown to be effective in cancer and AIDS treatment.
The polysaccharides in maitake have a unique structure, rendering them some of the most powerful to be studied (Chem Pharm Bull 1987:35:1162-8).
What makes maitake a particularly hot property is beta-D-glucan, its primary polysaccharide. Studies show that the body absorbs it readily, at which point it effectively stimulates interleukin-1, natural killer cells and macrophages, anti-tumor warriors that battle solid cancers (Chemotherapy 1990;38:790-6; also International Conference on AIDS, Amsterdam, 1992).
Effective And Safe
In addition to lab tests, trials on people have shown that maitake may offer powerful therapy against liver and stomach cancer (studies in China), breast and colon cancer (US research) and Kaposi's Sarcoma, the virulent cancer attacking AIDS sufferers.
Importantly, studies show that no side effects or interactions accompany maitake's efficacy.
Maitake fortunately has won the interest and enthusiasm of the scientific community. Currently, researchers at the Cancer Treatment Centers of America, headed by Denis Miller, MD, are completing an exhaustive test of the anticancer and immunostimulatory actions of maitake on folks with advanced colorectal cancer. These investigators hypothesize that the polysaccharide beta-glucans derived from the fruitbody of maitake fight tumors and boost immune function. "Though it cannot be said that maitake ...[is] the cancer cure," said Dr. Nanba in his closing remarks at the Adjuvant Nutrition in Cancer Treatment Symposium in Tampa, Florida, in October 1995, "one can safely say that they do maintain the quality of life of patients and improve the immune system, resulting in the possible remission of cancer cells with no side effects."
More Bodily Benefits
Maitake maven Dr. Nanba also has tested-with strongly positive results-the effect of maitake on blood glucose, insulin and triglycerides in mice, whose levels of all three substances declined when they were fed the mushroom (H. Nanba working paper, Anti-Diabetic Activity by Maitake Mushroom, 1994).
With colleagues, Dr. Nanba showed that maitake lowered blood pressure in hypertensive rats (Chem. Phann. Bu//36:1000-1006,1988). Other studies suggest it may accelerate weight loss.
This admirable adaptogen (meaning it helps the body adapt to stress and normalize its functions) is water soluble and may be eaten in food or taken as a supplement. Vitamin C is believed to intensify maitake's beta-glucans and enhance their absorption.
It's not just what you eat that may help protect against cancer, but what you drink as well. Research from China and Japan, where tea is the everyday drink and rates of several cancers like breast and prostate are lower, may persuade you to turn over a new leaf in your own beverage choice. One of the first studies to spark interest in tea came from Shanghai (Journal of the National Cancer Institute, June 1, 1994), where people who drank two to three cups a day were found to have about a 60% reduction in the risk of cancer of the esophagus. The reason: tea leaves contain compounds called polyphenols, potent antioxidants.
In fact, in tests at the University of Kansas, three of these, known as catechins, far outshone the common antioxidant vitamins C and E. Clinical trials are just starting, but early results are encouraging. A team of Chinese scientists reported that in a third of people with precancerous mouth sores who drank three cups of a mixture of green and black tea the lesions shrank significantly.
Researchers at the Saitama Cancer Center in Japan found that green tea seems to improve the prognosis of breast cancer. They followed a group of women with early-stage tumors for seven years. Those who drank more than five cups of green tea a day were only half as likely to suffer a recurrence as patients who consumed fewer than four cups a day.
And at the University of Indiana, toxicologist James Klaunig found that the lungs of cigarette smokers who drank the equivalent of six cups of tea a day suffered 40 to 50 percent less damage from the toxins in smoke, potentially lowering their risk of lung cancer and other pulmonary problems. Simultaneously, research from Purdue University suggests tea's cancer-discouraging powers go beyond being an antioxidant. Scientists Dorothy and D. James Morre showed that a tea catechin dubbed EGCG inhibits a growth-promoting enzyme on the surface of many cancer cells-happily without affecting normal cells. And researchers at the Ohio State University College of Medicine found that EGCG counteracted another enzyme, urokinase, that helps cancer cells spread. To top it off, Mayo Clinic scientists recently showed that EGCG prompted prostate cancer cells to commit suicide (Cancer Letters, Aug. 14, 1998).
So far, most tea research has focused on green tea, and investigators agree it's more potent than the black tea most Americans favor. But because both kinds come from the same plant, Camellia sinensis (it's the processing that makes the difference as black tea is fermented, green tea isn't) both contain cancer-fighting polyphenols, just in different quantities. As long as the tea you drink (even decaffeinated) is fresh brewed, it's likely to provide some benefit; powdered and prepared teas probably don't. And adding milk may dilute the effect.
Astragalus Against Tumors
Astragalus, an herb commonly used in Asia to boost stamina, has impressed western doctors for its potential for helping people cope with chemotherapy. As John Diamon, MD, W. Lee Cowden, MD and Burton Goldberg point out in the Definitive Guide to Cancer (Future Medicine), "Astragalus appears to protect the liver against the harmful toxic effects of chemotherapy and may be effective in treating terminally ill liver cancer patients." (They cite a study in the Jrnl of Ethnopharmacology 1990, 30:145-149.) In addition, they point out, research in Japan supports using a ginseng-astragalus combination to improve the function of natural killer (NK) cells which can boost immunity (Japanese Jrnl of Allergy, 37:2, 1998, 107-114).
Other studies confirm astragalus' potential in fighting off cancer. Research at the General Hospital of PLA, Beijing, showed that flavonoids (pigments) in astragalus could help protect cell membranes from oxidative damage caused by ultraviolet exposure (Chung Kuo Chung Yao Tsa Chih, 21(12):746-8; 1996 Dec).
A study of laboratory animals at Cunma University in Maebashi, Japan, found that Astragalus could help preserve immune function against the harmful side effects of chemotherapy (Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 15(2):101-3, 1995 Feb).
Like a flame attracting moths, garlic bulbs have irresistibly drawn the attention of medical researchers. A study at Aarhus University, Denmark, found that skin cells in laboratory dishes treated with garlic supplements lived longer, healthier lives than untreated cells (Jrnl Ethnopharm, 1994. 43:125-133).
Meanwhile, a long list of research demonstrates that garlic's phytochemicals may fight tumors and reduce the carcinogenicity of the pollutants and chemicals that assault us daily. A study in China reported in the American Journal of Chinese Medicine showed that garlic helped slow tumors in lab animals (1983, 11:69-73). Another study in the Journal of Nutrition found that compounds in garlic could "suppress the growth of human colon tumor cells" (126, 1355-1361).
Added to those benefits, Robert A. Nagourney, MD, reports in the Journal of Medicinal Food (1:1, 1998, 13-28), garlic may "modify the carcinogenicity of foodstuffs." In other words, studies show that garlic can make chemicals in foods like pork less likely to cause your cells to become cancerous. (Ind J Physiol Pharmacol, 39:347-353).
DNA, the stuff that genes are made of, face constant threats from free radicals, caustic molecules that can alter cellular structure and possibly cause genetic mutations that lead to cancer. But research into what are called oligomeric proanthocyanidins (OPC), flavonoids (pigments) derived from fruits vegetables, grape seed extract and the bark of maritime pine trees shows that OPC may be able to shield DNA from injury.
In particular, studies of a grape seed extract called Activin have demonstrated this substance can help liver cell DNA escape a destructive process called peroxidation (FASEB, 11:3, 2/28/97).
In these experiments, Activin demonstrated the ability to inhibit the growth of tumor cells as well as slow the replication enzymes of HIV viruses. This protective ability proved to be more potent than that of vitamin C, beta carotene and vitamin E.
What does the future promise to reveal? Scientists believe that many unexamined plants probably contain undiscovered phytochemicals that hold great potential for helping us fight the cancer epidemic.
Certainly, if the next few years produce as many results as the past decade, the next millennium will witness a long line of cancer-prevention discoveries. Before long, you should be able to take advantage of these potent substances.
As you gulp your garlic, tip your tea cup, mull your maitake, acquire Activin and await your astragalus, you may meditate on what may soon be added to our growing anti-cancer arsenal. Undoubtedly, scientists with a botanical bent will be uncovering more coveted anti-cancer secrets before too long.
Cancer at the Millenium - the war on cancer entering its third decade...
June 13, 2005 10:23 AM
Cancer at the Millenium by Harriet Brown Energy Times, May 1, 1999
With the war on cancer entering its third decade, the necessity grows clearer for medical science to engage the enemy on several fronts. Until recently, high-tech medical weapons like vaccines and gene therapy, inspired by a flood of insights into the molecular basis of cancer, garnered most of the hope, hype, headlines and research money. The science was sexy and the prospect of a "cure" dramatic. But, today, advocates of prevention receive equal, if not greater, attention.
Improving our diets and prudently supplementing with vitamins and minerals, can deliver a major preventive impact. Contentious experts concede that at least a third (and probably more) of all cancers can be blamed on a combination of eating too much of the wrong foods and not enough of the right ones.
The Dietary Difference
Though cancer can progress rapidly once it leaps past its inception, it develops over many years and in several stages. Beneficial compounds in food and supplements may intervene along a line that runs from initial exposure to carcinogens to the final step into outright malignancy. Nutrients may: - counteract environmental poisons and the toxic byproducts of liver metabolism
The Big Picture The dietary guidelines advocated by the American Cancer Society and the National Cancer Institute (which generally coincide with those of most health organizations) may sound familiar: Eat plenty of fruits and vegetables. Get lots of fiber. Limit fat, especially animal fat. Go easy on meat and avoid the cured variety (they contain nitrites). If you drink alcohol, do it in moderation. Watch your total calories, and your weight. Pretty straightforward stuff.
Carotenoids, as their name suggests, are orange and red pigments in fruits and vegetables, most notably carrots and tomatoes, although they're also in everything from sweet potatoes to spinach and brussels sprouts (in the latter their distinctive color is masked by green chlorophyll).
Lycopene, a carotenoid found primarily in tomatoes, displays double the free radical-fighting activity of beta carotene, the most widely studied carotenoid. Of 72 studies looking at consumption of tomatoes or tomato-based products reviewed in the February 1999 Journal of the National Cancer Institute, almost half showed a significant reduction in one or more of a variety of cancers.
Research shows that lycopene may be best at lowering a man's risk of prostate cancer. A 1995 Harvard Medical School study (Journal of the National Cancer Institute 1995; 87: 1767-76) queried nearly 48,000 male health-care professionals about their consumption of fruits and vegetables. The only foods that reduced their risk of prostate cancer were, apparently, tomato sauce, tomatoes, pizza (tomato paste). For those who ate ten servings a week, risk dropped 45 percent; with four to seven servings, 20 percent. In animal studies lycopene decreased the number and size of mammary tumors (Eleventh International Symposium on Carotenoids, 1996).
Tomatoes are one of the richest sources of lycopene. Cooking tomatoes helps by releasing the lycopene from the plant cell walls. Also, the oil in tomato sauce enhances absorption in the stomach. Lycopene is also available in supplements.
Wine drinkers rejoiced when resveratrol, a constituent of the skin of red grapes, was found to protect their hearts (by blocking oxidation of LDL cholesterol and discouraging blood clotting). Now they have another reason to toast this potent antioxidant. When researcher John Pezzuto at the University of Illinois at Chicago screened about 1,000 plants for anticancer activity, he came up with one whose active ingredient turned out to be resveratrol. In lab tests it squelched both free radicals and inflammation, two well-known cancer inducers (Science, 6/10/97). In a study with mice, resveratrol reduced the number of skin tumors by up to 98 percent compared to control animals. Because the effective doses were high (Pezzuto estimates a person would have to quaff about five gallons of wine a day to get the equivalent) and because more than a drink or two a day may raise the risk of breast cancer, researchers don't recommend nondrinkers take up wine. But supplements of synthesized resveratrol (as well as grape juice) may help.
Saturated fat is an authentic dietary villain. Aside from clogging arteries, it's a suspected contributor to several cancers, though the evidence is greater for some cancers (prostate) than for others (breast cancer)
Of the two other main categories of fats, monounsaturated and polyunsaturated, mono seems benign, if not positively protective. For example, in a study of the influence of diet on breast cancer, Greek researchers discovered that women who consumed higher amounts of olive oil (which is mostly mono) were less likely to be afflicted with breast cancer (Journal of the National Cancer Institute 1995: 87; 110-116).
When it comes to polyunsaturated fats, however, things get complicated. The fat that predominates in corn, sunflower and other vegetable oils, called omega-6, has long been associated with cancer risk in animal experiments. Likewise the type found in margarines, trans fats, which are partially saturated vegetable oils. On the other hand, the omega-3 fats called EPA and DHA, which are found primarily in deep- and cold-water fish like cod, mackerel, and halibut, protect against both heart disease and cancer. In an epidemiological study covering 24 European countries, British researchers established that mortality rates for colon and breast cancers declined as fish and fish oil consumption rose (British Journal of Cancer 1996: 74; 159-64). And Finnish scientists discovered that the breast tissue of women who had breast cancer contained significantly less DHA and EPA than the breasts of healthy women (Nutrition and Cancer 1995: 24; 151-160).
Experts believe the omega-3s' anticancer effect derives from its ability to tamp down the prostaglandins that stimulate inflammation. Chronic inflammation unleashes a steady stream of free radicals, which can damage DNA and thereby trigger cancer. Omega-3s also help the liver detoxify potentially harmful substances.
Fortunately for the fish-phobic, nonmarine sources of omega-3 fats include flaxseed and hemp oils.
Minerals to Lower Cancer Risk
n Calcium: possibly protective against colon cancer. In a recent trial (New England Journal of Medicine, 1/14/99) researchers gave people with a history of precancerous colon polyps either two 600 mg calcium tablets a day or a placebo for nine months and found fewer polyps. n Selenium: powerful antioxidant and supporter of immunity. Researchers find that cancer rates in various regions is lowered when soil and vegetables contain more selenium
In a selenium-depleted area in China afflicted with one of the highest incidences of stomach and esophageal cancer mortality in the world, scientists asked different groups to take various combinations of nutrients. After five years they found a significant reduction in the cancer rate among those who had gotten supplements of selenium, vitamin E and beta carotene (Biological Trace Element Research 1985; 7: 21-29). In the U.S. researchers studying the potential effectiveness of selenium supplementation for preventing nonmelanoma skin cancers came up with a surprise. The 200 mcg a day the subjects received for an average of 4.5 years had no impact on skin cancer but did significantly cut the rates of lung, colorectal and prostate cancers (Journal of the American Medical Association, 12/25/96).
More recently Harvard researchers determined that men with prostate cancer had much lower levels of selenium in their toenails (a measure of consumption) than healthy men (Journal of the National Cancer Institute, 8/119/98).
Cruciferous vegetables like broccoli, brussels sprouts, cauliflower and kale, have long been singled out for their association with protection against cancer. In a 1996 survey of 94 population studies and clinical trials focusing on consumption of cruciferous vegetables, 67 percent showed a reduced risk, the strongest link being with lung, stomach, colon and rectal cancers (Cancer Epidemiological Biomarkers 1996; 5: 733-748).
Scientists at Johns Hopkins showed that sulforaphane, from these plants, stimulates enzymes that help detoxify carcinogens generated in the liver. When they injected rats with a cancer-causing chemical, only 26 percent of the rodents pretreated with sulforaphane developed mammary cancer, compared to 68 percent of controls. Even animals who did come down with cancer had tumors that appeared later and smaller.
Other researchers have focused on a cruciferous-vegetable compound called indole-3-carbinol, which has proved especially effective against breast cancer cells. Recently, scientists at the University of California at Berkeley found that indole-3-carbinol, rather than acting as an anti-estrogen, (as had been thought), actually stops breast cancer cells by turning off a protein critical to their replication (Jrnal of Bio Chem, 2/13/98). Consequently, when treating certain forms of cancer, some doctors have paired indole-3-carbinol with the chemotherapy drug tamoxifen - which counteracts estrogen - and found that the combination has proven more potent than either separately.
Several decades ago British physician Denis Burkitt proposed that the low incidence of colon cancer among native peoples in South Africa was attributable to the fact that their diet was rich in fiber. The fiber, it was hypothesized, bulked up the stool, speeding its passage through the bowel and reducing the time carcinogens contact its lining; it also helped neutralize cancer-promoting bile acids.
This concept has been backed up by numerous studies. Recently, Harvard researchers sprinkled cold water on this idea, finding that an examination of the eating habits of more than 80,000 female nurses, could find no protective effect against colon cancer or precancerous polyps from consuming fiber (NEJM, January 21, 1999). Most experts' take on this apparent refutation: Maybe the "high fiber" intake in this case wasn't high enough, and this is just one study among many.
Fighting Breast Cancer
Fiber has also been linked to reduced rates of breast cancer. At first it was thought that if fat was a breast-cancer culprit, fiber might just be a marker for a low-fat diet. But a look at Finland undermined that idea: Finnish women eat both a lot of fat and a lot of fiber, and their breast cancer rate ranks much below that in the U.S., (where we eat gobs of fat and little roughage).
Fiber helps take estrogen out of circulation as it passes through the liver, while the isoflavones in many high-fiber plants and vegetables are themselves weak estrogens, which compete for slots on breast tissue's estrogen receptors. The special fiber in flaxseed oil called lignans act against estrogen in two ways: by binding its receptors and by inhibiting the enzyme that converts other hormones into estrogen.
Fiber comes in two basic forms, insoluble (e.g., wheat bran, celery, the skins of fruits and vegetables) and soluble (e.g., oat bran, citrus fruits, beans). Until a few years ago, scientists believed that cancer protection came mainly from insoluble fiber, but that thinking has turned around.
A soluble fiber called citrus pectin has been shown to halt the tendency of prostate, lung, breast and skin cancers to metastasize, or spread (e.g., Journal of the National Cancer Institute 1995; 87: 3448-353). Typically cancer turns deadly only when it gets into the bloodstream and invades new territory. Modified citrus pectin appears to stop this aggression by preventing cancer cells from attaching to healthy tissue.
While the name inositol hexaphosphate (IP6) sounds like a mouthful, many of us consume mouthfuls of this natural substance every day - in foods like corn, rice, whole-grain cereals, oats and wheat.
But now scientists have isolated IP-6 and found that this powerful antioxidant can slow the destructive cellular processes that lead to tumors. In a study published in Anti-Cancer Research (Nov/Dec 1998), scientists at the University of Maryland School of Medicine demonstrated that IP-6 could shrink liver tumors in laboratory animals.
The researchers believe that IP-6 can help prevent cancer and also be useful in lowering the risk of health problems like kidney stones and heart disease. Research like this continues to expand our knowledge of how to lower the risk of cancer. In the next millennium, with more and more information making its way into the media and onto websites, our power and the responsibility to reduce our risk of cancer will continue to grow and offer new possibilities.
Herbs in Perspective
June 10, 2005 10:25 PM
Herbs in Perspective by Phyllis D. Light, RH-AHG Energy Times, June 16, 2004
"I don't claim a cure...I just try to give people some ease," noted Tommie Bass, a traditional Southern herbalist whose life has been the topic of several books, including Mountain Medicine by Darryl Patton (Natural Reader Press) and Trying to Give Ease by John Crellin and Jane Philpott (Duke University Press). That philosophy reflects the perspective embraced by herbalists for eons.
The traditional use of herbs is incorporated into all cultures. Herbs were the first medicine and the origin of what we now call modern medicine. These plants have not been prescribed to conquer specific illnesses but instead nourish the body and aid in building overall health.
Observation, psychological need and human instinct form the foundation of traditional herbal knowledge and use. This knowledge has been passed down through generations based on practice and experience. The result: a depth of information about the safe and effective use of herbs that spans thousands of years.
The goal of a traditional herbalist is to bring the body into balance (homeostasis), prevent disease and support immune functioning. Unfortunately, any kind of therapeutic knowledge can be misused, and that has happened with some herbs, causing some people to question herbal medicine's safety.
As more people turn to natural therapies, scientists have begun to perform evidence-based research into their safe and effective use. The good news is that much of this research has validated the effectiveness of herbs and supplements.
Echinacea to the Rescue
Do the sniffling sneezes that herald a cold have you reaching for your bottle of echinacea? If so, you are in good company. Echinacea (Echinacea spp) is one of the top-selling herbs.
The colorful American prairie plant was extremely popular during the early 1900s, until the use of modern antibiotics relegated it to the back shelf. But a resurgence of interest in herbs propelled echinacea back into the mainstream in the second half of the twentieth century. And this herb boasts an impressive body of research and has an excellent record of safety.
For instance, researchers at Virginia Commonwealth University School of Pharmacy have found echinacea to be effective in supporting the body's defenses against upper respiratory tract infections and for reducing the duration of discomforts that accompany the common cold (Pharmacotherapy 2000; 20(6):690-7).
Although studies have not confirmed its ability to prevent colds, echinacea is widely used by many folks for just that purpose. Researchers have found that echinacea's effectiveness may drop if you use it for eight straight weeks (Am J Health-Syst Pharm 1999; 56(2):121-2). So if you take it for a couple of months, take a couple of weeks off before using it again.
St. John's wort is another herb with ancient origins that has experienced a modern resurgence. Named after St. John the Baptist, St. John's wort (Hypericum perforatum) is generally in bright yellow bloom around St. John's Day (June 26). According to herbalist Michael Tierra, author of The Way of Herbs (Pocket Books), St. John's wort affects the liver and the nervous system. In 1984, the German Commission E, a recognized herbal authority, approved St. John's for depressive disorders, and in topical form for acute injuries and first-degree burns.
Modern research has reaffirmed the use of St. John's wort in the short-term treatment of mild to moderate depression (Cochrane Review Issue 2, 2004). It has also been found to be useful in premenstrual depression (Int J Psy Med 2003; 33(3):295-7). (Researchers have found that the herb may alter how the body processes some prescription medications, so check with your healthcare provider before using such medicines along with St. John's wort.)
King of Herbs
" Ginseng (Panax) received the lofty title, King of Herbs, due to its reputation as a tonic and its ability to stimulate the body into healing," notes herbalism writer Darryl Patton. This plant was once so popular in China that it was worth its weight in gold.
In fact, ginseng is the popular name for two different types of ginseng, American and Korean (Panax quinquefolium and P. ginseng). Both are considered adaptogens, or substances that help the body deal with stress more effectively. And modern research has found that ginseng can be used to improve overall energy and vitality, and to help the body deal more effectively with chronic stress (J Pharm Sci 2003 Dec: 93(4):458-64).
Researchers have found that ginseng helps boost the immune system (J Med Food 2004 Spring; 7(1):1-6). This ancient herb is also a powerful antioxidant that confers protection on the heart (Biochem Biophys Acta 2004 Feb 24; 1670(3):165-71). In other studies, ginseng has been found to reduce symptoms of menopause, improve endurance and lower blood sugar levels. To avoid overharvesting wild ginseng, most of the herb on the market is now grown on farms.
Ode to Ginkgo
Known as the Living Fossil, ginkgo is the oldest known plant in the world. A native of Asia, ginkgo (Ginkgo biloba) is now found in many US cities, where it has been planted as a quick-growing shade tree. Traditionally, ginkgo was used for disorders and diseases of the lungs and the kidneys, as a remedy for bronchitis and to improve circulation in older people.
Ginkgo contains substances that act as potent antioxidants by scavenging cell-damaging free radicals, and it is thought to help reduce the risk of disease. By opening capillaries, ginkgo increases circulation, and enables nutrients and oxygen to move around the body, especially to the extremities.
Indeed, recent research indicates that ginkgo may ease pain associated with arterial disease in the legs (Am J Med 2000; 108:276-81). Other studies support the use of ginkgo for acute stress (J Pharm Sci 2003 Dec; 93(4):458-64) and some cases of hearing loss (Acta Otolaryngol 2001; 121:579-84).
In a UCLA Neuropsychiatric Institute study on ginkgo, researchers found significant improvement in the verbal recall of people who had age-related memory problems. According to Dr. Linda Ercoli, lead author of the study, "Our findings suggest intriguing avenues for future study...with a larger sample to better measure and understand the impact of ginkgo on brain metabolism."
Traditionally, fiery ginger (Zingiber officinale) has been used to aid digestion, reduce nausea, relieve gas, reduce symptoms of arthritis and strengthen the heart. Modern researchers have started to validate these traditional uses; ginger has reduced the nausea and vomiting of morning sickness in studies (Aust NZJ Obstet Gynaecol 2003 Apr; 4392:139-44).
Meanwhile, researchers at the University of Minnesota have applied for a patent on a substance found in ginger, believing it to have anticancer activity. According to Ann Bode, "Plants of the ginger family have been credited with therapeutic and preventive powers and have been reported to have anticancer activity."
Ginger can be found in natural food stores as fresh or dried root. It often appears in small amounts in herbal formulas as a carrier herb-one that helps move other herbs around the body.
The best medicine combines the health support of herbs with the scientific rigor of conventional medicine. And as scientists continue to search for new medicine from ancient remedies, we can enjoy the best of both perspectives.
Immunity - The Big Picture
June 10, 2005 09:51 PM
Immunity: The Big Picture by Brian Amherst Energy Times, August 3, 1999
Your body wants to be well. Outfitted with a battalion of defenses for strategic deployment, your immune system explodes with resistant force at the first sign of infective invasion.
Think of the time a tiny splinter embedded itself in your thumb. By bedtime, the spot rose and reddened; by morning, white blood cells had launched their campaign, building a hot, throbbing fortification. By day's end, the bit of wood was propelled to the surface and ejected by the immune system warriors. Once again, a foreign assailant was summarily ousted.
The Protective Force
"Supporting the immune system is critical to good health. Conversely, good health is critical to supporting the immune system." So write naturopathic doctors Michael T. Murray and Joseph E. Pizzorno in their Encyclopedia of Natural Medicine (Prima).
Maintaining the immune system requires a comprehensive program of wholesome diet, resilient attitude, fitness enhancing activity and nutrients keyed to the clear and specific needs of this energetic machine.
The all-star lineup for immune sustenance: a high-potency multiple vitamin/mineral formula, vitamins C and A, bioflavonoids, isoflavones, zinc and selenium, antioxidants like ActiVin (grape seed extract) and pycnogenol (French maritime pine bark), as well as the botanicals echinacea and astragalus.
But optimal partnering with your immune system also benefits from understanding its workings.
Lymph, a milky fluid consisting of water protein and immune cells, is the essence of the immune system. Powered by muscle movement (an important reason why exercise boosts immunity), the lymphatic system collects and transports lymph to the lymph nodes. These nodes contain certain immune cells and filter out invading antigens, as well as produce antibodies, before siphoning the lymph out into the bloodstream.
If you've ever had "swollen glands," that means your lymph nodes have been in overdrive.
Macrophages are the immune cells that filter lymph, consuming bacteria and cellular debris while protecting the lymph system from invasion and damage.
The White Blood Cell Album
In Monocytes collect cellular trash after infections and can trigger immune responses; eosinophils can eliminate foreign particles and, with basophils, are involved in immune response.
In Lymphocytes include varieties of T cells, which work with other white blood cells or attack and destroy foreign tissue, cancer cells or virus-infected cells; B cells that produce antibodies that bind to bacteria, viruses or tumors; and natural killer cells (NKCs) that destroy cancerous or virally-infected cells.
(Based on information in the Encyclopedia of Natural Medicine; The Road to Immunity: How to Survive and Thrive in a Toxic World (Pocket Books) by Kenneth Bock, MD, and Nellie Sabin; and the Johns Hopkins Family Health Book (Harper Resource).
Keep the System Sound
"But you must always be sure to maintain the mind-body-spirit link," he told Energy Times. "For the mind, it could be exercise, yoga or meditation. Evidence shows improved immune system responses from these therapies. And in any case, you never read in the headlines that somebody has been admitted to the emergency room overdosing on meditation.
"Intentionality also is an important part of the mind link: believing you are going to fare well. For your spirit, you must ask yourself such questions as, Do I feel connected to others?
"For the body, a daily multivitamin and mineral supplement. Much depends on your community: I live on Long Island, where there is a high incidence of breast cancer, so I would recommend green tea and isoflavones from soy products for women."
Dr. Benjamin stresses moderation in the use of immune-intensifying supplements, among which he cites mixed carotenoids, zinc and vitamin E.
The Soy Solution
In a study conducted by the University of Southern California at Norris and published in the March 4, 1998 Journal of the National Cancer Institute, researchers reported that genistein, an active component of soy products, short-circuits the ability of tumor cells to elude destruction by the immune system due to an excess of defensive stress proteins.
Genistein seems to make cancer cells vulnerable to the immune response. Researchers at Wake Forest University told participants at the January 1999 meeting of the American Association for the Advancement of Science that dietary or supplemental soy fed to monkeys counteracted cell proliferation that is a cancer precursor.
That Championship C
Immune cells are known to accumulate and retain high levels of vitamin C. Researchers at Memorial Sloan-Kettering Cancer Center in New York now understand how that happens: Proteins called growth factors (which control growth and production of immune cells) also increase those cells' ability to take up vitamin C.
These researchers, reporting in the April 1998 issue of the journal Blood, explain that the additional glucose that the growth factors pump into immune cells (for enhanced energy), plus extra vitamin C, intensify immune response.
And folks with higher levels of vitamin C in their blood serum experience less cell damage from free radicals that leads to cancer, heart and pulmonary disease and other chronic conditions.
Scientists at the University of Buffalo (addressing the June 13, 1997 meeting of the Society for Epidemiologic Research) deduced from studying population groups that high levels of vitamin C are associated with low oxidative stress and lower risk of cell damage.
From A to Zinc
In Colostrum, the pre-milk liquid produced by mammals during the first 24 to 48 hours after birth, took the spotlight recently as a supplement imbued with multiple immune factors and natural antibiotics that augment body's immune response. A 1992 study showed that bovine colostrum might be able to reduce and prevente infections in immune deficient folks, especially those with AIDS.
In University of Pittsburgh Cancer Institute researchers found for the first time (on laboratory animals) that vitamin D appreciably inhibits widespread prostate cancer by binding to cancer cells and triggering cell death or their transformation to benign cells.
In Vitamin E exerts formidable immune-enhancing influence on both antibody and cell-mediated immunity. One fundamental study in the Journal of the American Medical Association (245, 1981: 53-58) established conclusively that vitamin E deficiency results in significant impairment of immune function. Later studies demonstrated that it reduces prostate cancer by up to one-third.
In Coenzyme A, described as a metabolic enzyme, takes part in starting numerous body processes that provide energy for the immune system. If you ever run short of this enzyme, fat processing within your body would grind to a halt.
in Researchers looking at a substance with the tongue twisting name 3-acetyl-7-oxo-Dehydroepiandro-sterone, believe it aids immunity by quelling stress hormones.
in Mushrooms contain natural substances called polysaccharides, believed to enhance immunity. In particular, maitake mushroom, which conveys the immune booster beta-D-glucans, is reputed to help fight infections and drop blood pressure.
in Men and women taking selenium supplements for 10 years had 41% less total cancer than those taking a dummy, according to a January 1997 study by Cornell University and the University of Arizona. Other studies have shown it to reduce the risk for colon cancer by about 60%. n Zinc may provide immediate protection against the all too common cold. Scientists at the University of Florida were the first to apply genetic fingerprinting methods like those used in criminal and paternity investigations to understand how nutrients directly affect human immune cells.
The study, in the April 1998 Journal of Nutrition, demonstrates that zinc signals cells to make the protein metallothionein, which protects against infections, toxins and other stressors.
Phytochemicals a la Carte
n Isoflavones from soy, fight angiogenesis, the process by which new blood vessels form to supply nutrients to cancerous growths. n Sulforaphane in broccoli, kale and cabbage activates anticancer enzymes.
n Omega-3 fatty acids in cold water fish block the synthesis of prostaglandins, natural compounds in the body that promote tumor growth.
n Ginger contains antioxidant compounds, each more potent than vitamin E. Recent studies on mice show ginger can prevent skin tumors. n Rosemary contains carnosol which deactivates carcinogens and helps limit the effects of prostaglandins.
Sometimes the world can look like a dangerous place, especially when you're sick and tired much of the time. But in the search for immunity, menus of health help like this ensure that no matter what your immunity needs, a boost can be yours with the proper nutrient selection.
June 10, 2005 09:44 PM
Breast Cancer by Joseph L. Mayo,MD Mary Ann Mayo, MA Energy Times, May 2, 1999
What do you fear most? Bankruptcy? Floods? Heart disease? If you're like many women, breast cancer stands near the top of that dreaded list.
But that fear doesn't permeate other cultures the way it does ours.
A woman like Mariko Mori, for instance, 52 years old, Japanese, worries about intense pressures beginning to burden her toddler grandson. But worry about breast cancer? Hardly.
In Indiana, Mary Lou Marks, 50, has similar family frets, mulling over her 28-year-old daughter's career choice.
But on top of that, when Mary Lou tabulates her other worries, she recoils at the thought of breast cancer. She's heard about her lifetime risk: 1 in 8. Meanwhile, Mariko's is merely 1 in 40, according to Bob Arnot's Breast Cancer Prevention Diet (Little, Brown).
New studies have found the effect of carrying the gene linked to breast cancer, which is responsible for only 5 to 10% of breast cancer incidence, is not as great as first suspected. Earlier estimates that the gene reflects an 80% chance of incurring breast cancer by age 70 has been recalculated to be only 37% (The Lancet, 1998;352:1337-1339).
Complex Causesbr> Researchers agree: No one factor is solely responsible for breast cancer. Risk depends on many factors, including diet, weight, smoking, alcohol consumption, activity level and, of course, those genes.
Regardless of their actual chance of getting breast cancer, women worry. Mary Lou faces no factors that would place her in particular jeopardy. But her anxieties about radical therapies and medical expenses paralyze her: She forgets to visit her health care provider and skips her annual mammogram appointments. Mary Lou's daughter, perhaps in reaction to her mother's gripping fears, campaigns ardently for cancer prevention, educating herself and mobilizing against the cumulative effects of known cancer risks. Smart young woman: A malignancy, after all, can take years to develop. A tumor must swell to one billion cells before it is detectable by a mammogram.
The soy-rich regimen of Japanese women like Mariko Mori, for example, helps to explain the low breast cancer rates in Asian countries (see box at center of the page).
Tomatoes, because of their high quotient of the carotenoid lycopene, have been found to protect cells from the corrosive clutches of oxidants that have been linked with cancer in 57 out of 72 studies (The Santa Rosa Press Democrat, February 17, 1999, page A6, reporting on a Harvard Medical School study). For more on tomatoes see page 16.
But there's no one magic anti-cancer food or diet. Eating to prevent breast cancer requires a balanced menu with fiber, healthy fats, phytoestrogens and antioxidants, all fresh and free of chemical additives.
Modifying the balance and type of estrogen, the female sex hormone produced by the ovaries, offers an important breast cancer safeguard. Fat cells, adrenal glands and, before menopause, the ovaries, produce three "flavors" of estrogen, the strongest of which, estradiol, is believed to be carcinogenic when too plentiful or persistent in the body.
Estrogen does its work by attaching to estrogen receptors. Receptors are particularly numerous in the epithelial cells that line milk sacs and ducts in the breasts.
A receptor site is like a designated parking spot: Once estrogen is parked there it triggers one of its 400 functions in the body, from preparation of the uterus for pregnancy to intensifying nerve synapses in the brain.
The food we eat can be a source of estrogen; plant estrogens, called phytoestrogens, are much weaker than the body's estrogens, but they fit the same receptors. Phytoestrogens exert a milder estrogenic effect than bodily estrogen and are capable of blocking the more potent, damaging versions.
Soy also contains genistein, an "isoflavone" very similar in molecular form to estrogen but only 1/100,000 as potent. Because of its structure, genistein can attach to cells just as estrogen does; it also helps build carriers needed for binding estrogen and removing it from the body (Journal of Nutrition 125, no.3 :757S-770S). It acts as an antioxidant to counteract free radicals.
Soy is most protective for younger women. Postmenopausal women benefit from soy's ability to diminish hot flashes and for cardiovascular protection, especially in combination with vitamin E, fiber and carotene (Contemporary OB/GYN, September 1998, p57-58).
Experts don't know that much about the cumulative effect of combining hormone replacement with soy, herbs and a diet high in phytoestrogens. Menopausal women who boost their estrogen this way should work with their health care providers and monitor their hormonal levels every six to 12 months with salivary testing.
The Vegetable Cart
Fiber from fruits, vegetables and whole grains reduces insulin levels and suppresses the appetite by making make us feel full, thus helping with weight control, so important to resisting cancer. Fiber also helps build estrogen carriers that keep unbound estrogen from being recirculated and reattached to the breast receptors.
Cellulose, the fruit and vegetable fiber most binding with estrogen, also rounds up free radicals that damage DNA within cells.,p> Feeding the Immune System Despite heightened public awareness and efforts to stick to wholesome, healthful diets, experts increasingly link poor nutrition to depressed immune systems. Many Americans are at least marginally deficient in trace elements and vitamins despite their best attempts to eat well; that's why a good multivitamin/mineral is wise, even mandatory. Vitamins given to people undergoing cancer treatment stimulate greater response, fewer side effects, and increased survival (International Journal of Integrative Medicine, vol. 1, no. 1, January/February 1999).
Nutrients tend to work synergistically on the immune system. They should be taken in balanced proportions, and in consultation with your health care provider.
n Riboflavin (B2), pyridoxine (B6), pantothenic acid (B5), zinc and folate strengthen immunity. Selenium, in lab culture and animal studies, has helped kill tumors and protect normal tissues.
n Beta-carotene and vitamins A, E and C are antioxidants. Vitamin C enhances vitamin E's effects, boosting immunity and protecting against cell damage. The antioxidant isoflavones in green tea, with soy, convey the anticancer effects of the Asian diet. Research shows actions that discourage tumors and gene mutations.
The food you eat influences hormones. Excess sugar raises insulin, which acts as a growth factor for cancer and interferes with vitamin C's stimulation of white blood cells. It may contribute to obesity.
Alcohol is converted to acetaldehyde, which causes cancer in laboratory animals. It affects gene regulation by decreasing the body's ability to use folic acid. It increases estrogen and the amount of free estradiol in the blood. The liver damage that accompanies high alcohol consumption frequently reduces its capacity to filter carcinogenic products, regulate hormones and break down estrogen. Studies of alcohol consumption have caused experts to estimate that drinking more than two alcoholic beverages a day increases breast cancer risk by 63% (OB-GYN News, November 1, 1998, p. 12).
Fat Can be Phat
Fat cells produce estrogen. Excess fat stores carcinogens and limits carriers that can move estrogen out of your system.
Once estrogen has attached itself to a receptor, the health result depends on the type of fat in the breast. Saturated fat, transfatty acids and omega-6 fat from polyunsaturated vegetable oils such as safflower oil, peanut, soybean oil, corn oil and in margarine can increase the estrogen effect and trigger a powerful signal to the breast cell to replicate.
Breast tissue is protected by omega-3 fat chiefly from fish and flaxseed and by omega-9 from olive oil. Salmon once a week or water packed tuna three times a week are particularly beneficial. Fish oil supplements processed to reduce contaminates are available. Cod liver oil isn't recommended: its vitamin A and D levels are too high.
Flaxseed is the richest known plant source of omega-3. Use a coffee grinder to benefit from the seed and oil for the full estrogen effect; sprinkle ground flaxseed over cereal or fold into baked goods. Drizzle flaxseed oil, found in the refrigerator section of your health food store, over salads or cereal. (Store the oil in the refrigerator.)
Olive oil, especially in the context of the so-called Mediterranean diet of vegetables, omega-3-rich fish and fresh fruit (Menopause Management, January-February 1999, p. 16-19), lowers the risk of breast cancer (The Lancet, May 18, 1996;347:1351-1356).
Selecting Organic Food
Buy or grow fresh, organic foods whenever you can. When grilling meat, fish or poultry, reduce the area where carcinogens may accumulate by trimming fat. Charred, well-done meat is known to be carcinogenic. When grilling, marinate meat first and reduce the cooking time on the grill by slightly precooking.
Cancer prevention is an interlocking puzzle requiring the limitation of fat consumption, weight control, exercise, stress reduction and care for psychological and spiritual balance. Possessing more cancer fighting pieces makes you more likely to be able to complete the prevention picture.
Joseph L. Mayo, MD, FACOG and Mary Ann Mayo, MA, are the authors of The Menopause manager: A Safe Path for a Natural Change, an individualized program for managing menopause. The book's advice, in easy-to-understand portions, isolates in-depth explanations with unbiased reviews of conventional and alternative choices. A unique perspective for mid-life women who want to know all their options.
Also from the Mayos - The HOW Health Opportunities For Women quarterly newsletter to help women learn HOW to make informed health choices. Learn HOW to: - Choose nutritional supplements
Take it to Heart - Lower Cholesterol
June 09, 2005 06:05 PM
Take it to Heart by Dawn Lemonathen Energy Times, January 2, 2002
Lifestyle is key to bettering your odds of beating heart disease. A few simple, everyday heart-friendly habits can help your heart help you. Right now, heart attacks and other cardiovascular complications like stroke have reached sky-high levels across the US.
Nearly 60 million Americans suffer from one of the various forms of cardiovascular disease and these often fatal complications cause more than 40% of all deaths in the United States. Statistics show that nearly a million Americans succumb to heart problems every year. The humongous cost: Heart disease and stroke consume almost $260 billion annually. Heart disease is the top cause of death for older Americans and remains the leading cause of death for all Americans age 35 and older. Coronary heart disease (CHD), also known as ischemic heart disease, is the most frequent cause of death for adults in the United States-accounting for more than 500,000 deaths a year. And even though most women have had their consciousness raised about their risk of cancer, particularly breast cancer, in fact, their chances of dying from one of the forms of heart disease is double their risk of succumbing to one of the forms of cancer. And ten times more women die from cardiovascular problems than die from breast cancer.
Cholesterol and Heart Health
Nuts and Heart Health
Vegetarianism vs Heart Disease
The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease
June 09, 2005 05:22 PM
The Latest Breakthroughs in Garlic Research
on Cancer and Cardiovascular Disease
Presented at the 2005 World Garlic Symposium
Many of the world’s top-level scientists gathered in Washington D.C. this week for the 2005 Garlic Symposium, entitled, “Significance of Garlic and its Constituents in Cancer and Cardiovascular Disease.” The conference provided current scientific information about the effect of garlic and its constituents on health and performance. The symposium was held at the Georgetown University Conference Center on April 9-11, 2005.
“For the first time in seven years authorities in various fields of garlic research from all over the world to provide the latest updates, specifically regarding aged garlic extract and its actions in diseased states including heart disease and cancer,” commented Dr. Matthew Budoff, M.D. cardiovascular researcher at UCLA. “Garlic has been used medicinally for thousands of years in virtually all ancient cultures. Now, new metabolic roles for garlic are being proposed and there are many promising lines of research.”
Presentation highlights included:
Effect of aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study that determined that the atherosclerotic plaque burden detected by electron beam tomography (EBT) changed significantly with the use of aged garlic extract, Patients in Dr. Budoff’s study were able to significantly lower their total cholesterol, blood pressure, homocysteine and LDL cholesterol oxidation levels with aged garlic extract supplementation.
“Garlic is turning out to be a major player in cancer and heart disease prevention and control, especially in combination with drug treatments,” said Richard Rivlin, M.D. of Strang Cancer Prevention Center at Cornell. “It’s also showing us that we can start early. It’s madness to treat cancer and heart disease in their advanced stages. We need to start early and aged garlic extract is an excellent way to do that.”
Almost 400 scientific studies have been completed on aged garlic extract, done in major universities worldwide. These studies have focused on a variety of heart disease risk factors such as cholesterol, high blood pressure, homocysteine levels, inhibiting LDL oxidation, anti-platelet aggregation and adhesion, stimulating blood circulation; in addition to other studies on immune stimulation, cognitive effects, liver function and anti-tumor effects. .
PRECLINICAL PERSPECTIVE ON GARLIC AND CANCER. John A. Milner, National Cancer Institute, Rockville, MD 20892
Mounting evidence points to the anticancer properties of fresh garlic extracts, aged garlic, garlic oil, and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis. A block in carcinogen activation through modulation of cytochrome P450-dependent monooxygenases and/or acceleration of carcinogen detoxification via induction of phase II enzymes likely account for some of this protection. The block in preneoplastic lesions and/or tumors in several sites suggests a generalizable mechanism. The efficacy of water- and lipid-soluble allyl sulfur compounds against chemical carcinogenesis appears comparable, although more studies are needed. A shift in sulfhydryl groups, redox status or enzyme catalysis may account for some of the phenotypic changes. They may also account for the observed hyperphosphorylation of specific cell cycle related proteins and histone hyperacetylation; both of which have been correlated with suppressed tumor cell proliferation. Several forms of allyl sulfur compounds are effective in blocking cell division and inducing apoptosis, but notable differences in the efficacy among these various compounds and across tumor types are evident. While the expression of many genes and proteins can be influenced by allyl sulfides; the challenge is to determine which is responsible for a phenotypic change. Additional studies are needed with more modest exposures and over prolonged periods and that utilize transgenic and knockout models to assist in the identification of molecular targets. Finally, additional research is needed to identify sensitive “effect” and “susceptibility” biomarkers that can ultimately be used to identify responders from non-responders.
INHIBITION OF CORONARY ARTERIAL PLAQUE ACCUMULATION BY GARLIC. Matthew Budoff, Harbor-UCLA Medical Center, UCLA School of Medicine, California, USA
Effect of Aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study to determine whether the atherosclerotic plaque burden detected by electron beam tomography (EBT) will change at a different rate under the influence of AGE or placebo. EBT can non-invasively quantitate the amount of coronary calcification and track atherosclerotic plaque over time. Nineteen of 23 patients completed the study protocol. The patients were well matched for age, gender, statin use and cardiac risk factors. Patients underwent EBT and blood testing at baseline, and then again after 12 months of randomization. The average change in the calcium score (Volumetric method) ± SD for the AGE group (n = 9) was 7.5 ± 9.4% over the one year. The placebo group (n = 10) demonstrated 22.2 ± 18.5% annual progression, significantly greater than the treated cohort (p = 0.01). While there were no significant changes in cholesterol parameters, or C Reactive protein between the groups, high density lipoproteins and plasma homocysteine in the AGE group demonstrated a trend toward improvement compared to the placebo patients. Thus, although this is a small-scale trial, it demonstrates the potential of AGE to inhibit the rate of atherosclerosis (progression of coronary calcium), as compared to placebo over one year. Larger studies need to be performed to assess this potential anti-atherosclerotic therapy and the impact on coronary events.
INFLUENCE OF GARLIC ON ENDOTHELIAL DYSFUNCTION IN HYPERHOMOCYSTEINEMIA. N. Weiss, N. Ide, T. Abahji, L. Nill, C. Keller, U. Hoffmann. Klinikum der Universität München, D-80336 Munich, Germany
Endothelial dysfunction (ED) due to decreased bioavailable nitric oxide (NO) by increased vascular oxidant stress plays a critical role in the vascular pathobiology of hyperhomocysteinemia (hhcy). Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. We performed a placebo-controlled, blinded, cross-over study to examine whether AGE prevents macro- and microvascular ED during acute hhcy induced by an oral methionine challenge in healthy subjects. Acute hhcy leads to a significant decrease in flow-mediated vasodilation of the brachial artery as determined by vascular ultrasound, indicative of macrovascular ED, as well as a decreased number of recruited nailfold capillaries during postischemic reactive hyperemia as determined by videomicroscopy, and to a decreased ratio of acetylcholine (endothelium-dependent) vs. sodium nitroprusside (endothelium-independent) iontophoresis induced skin perfusion as measured by laser doppler flowmetry, indicative of microvascular ED. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute hhcy on endothelium-dependent brachial artery vasodilation and on acetylcholine-induced stimulation of skin perfusion. Whether or not this is accompanied by changes in biochemical parameters of ED is still under investigation. It is concluded that AGE may at least partly prevent a decrease in bioavailable NO during acute hhcy.
David Heber, MD, PhD, FACP, FACN
Professor, UCLA Department of Medicine - Division of Clinical Nutrition, at the David Geffen School of Medicine, UCLA, and UCLA School of Public Health; Director, UCLA Center for Human Nutrition; Director, NIH Center for Dietary Supplement Research in Botanicals (CDSRB); Director, NCI-funded Clinical Nutrition Research Unit; Vice Chair, UCLA Collaborative Centers for Integrative Medicine; Member, UCLA's Jonsson Comprehensive Cancer Center
Matthew Budoff, MD, FACC
Matthew Budoff, MD, FACC, is an associate professor of medicine at the UCLA School of Medicine and program director for the Division of Cardiology, as well as director of the Electron Beam CT Laboratory at Harbor-UCLA Medical Center in Torrance, Calif. He completed his undergraduate work at University of California, Riverside, and earned his medical degree at George Washington University in Washington D.C. Dr. Budoff’s efforts to identify and modify risk factors for cardiovascular disease using electron beam CT have been extensively published. His latest research focuses on the progression of arteriosclerosis.
Ellagic Active - Raspberry Extract - Promotes Healthy Cells ...
June 01, 2005 01:22 PM
You may think raspberries are strictly a summertime indulgence. Yet scientists know this simple fruit is far more valuable than a delicious snack or gourmet dessert. Raspberries have the highest content of ellagitannins— amazing health compounds— which are converted into ellagic acids in the body. These compounds are highly regarded for their positive effects on the growth and regulation of various cells and tissues, including those in the breast, pancreas, esophageal, skin, colon and prostate. Ellagic acid is also a powerful antioxidant (even stronger than vitamin C) that supports DNA integrity and promotes overall cell health, according to animal and in-vitro research. Source Naturals offers ELLAGIC ACID in response to a breakthrough in cell research. We strive to be ahead of mainstream nutritional science and are passionate about our commitment to informed health choices.
Dieticians have long stressed the importance of the consumption of fruits and vegetables for general health and well-being, but now these food items are being recognized as even greater contributors to human health. We know that ellagic acid binds to DNA, and acts as a shield, protecting DNA and increasing the expression of the enzyme p21, which arrests division of cells with DNA damage. Raspberries contain phytochemicals that provide protective action: One study showed that ellagic acid was able to induce the production of NAD(P)H:quinone reductase (QR), a major detoxification enzyme. Ellagic acid acts as a free radical scavenger to “bind” irritant-causing chemicals, making them inactive. Ellagic acid stimulates the activity of the enzyme glutathione-S-transferase that supports healthy cell growth.
Raspberry is also a traditional remedy in support of the gastrointestinal and respiratory tract. It is used to promote healthy blood vessels, as a mouth and throat remedy and is said to help maintain a “normal, balanced feeling” in the stomach. Research studies on the protective effects of ellagic acid have been extensive—there are approximately 126 published studies. Berries also contain a natural form of salicylates, which provide cardio support. British researchers analyzed the blood of subjects and found salicylates were present from dietary sources, including raspberries and blackberries. Researchers at the National Center for Health Statistics (NCHS) in Hyattsville, Maryland established a connection between reduced health risks and increased intake of salicylates. Animal tests also suggest that red raspberry may reduce levels of glucose (blood sugar) to support normal blood sugar levels.
Research in the past decade has determined that ellagic acid is one of the most exciting and promising compounds for its striking effect on cell division, regeneration and growth. While ellagic acid has been found to occur naturally in 46 different foods, red raspberry has been identified as having the highest natural content. Each tablet contains 300 mg of raspberry leaf extract (40% ellagitannins), which is ten times higher than other raspberry products. Source Naturals again joins forces with your natural foods retailer to bring you this unparalleled supplement.