Search Term: " brief "
What are the best food sources of vitamin K?
Date:
April 02, 2019 02:08 PM
Vitamins, Minerals and Health, oh my! In recent years, the usage of more uncommon vitamins has been promptly on display. Have you ever wondered just exactly what Vitamin K does? Look no further. Zoey Sky has outlined what this particular vitamin does, why it is important for you and gives a few brief warnings on when not to take this. Along with these helpful tips, she has provided a few foods in which Vitamin K is most prevalent, their vitamin count and additional vitamins they may contain. Key Takeaways:
"Following a healthy diet offers many benefits, such as improved overall physical and mental well-being." Read more: https://www.naturalnews.com/2019-02-03-what-are-the-best-food-sources-of-vitamin-k.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6112) Why you should NEVER hit the snooze button on your alarm clock - and always get 8 hours of sleep!
Date:
September 20, 2017 12:14 PM
Getting enough sleep is important. That is when your body recharges. It is good for your physical and mental health to get enough. This will keep you from having to hit your snooze button a lot in the mornings as well, and this will help you get places on time. Not getting enough sleep can hurt your schooling or job since you can't get up and there on time. This is not good for you. You could even be fired over it. Key Takeaways:
"Professor Michael Irwin, a sleep scientist at the University of California, Los Angeles, has performed landmark studies revealing just how quickly and comprehensively a brief dose of short sleep can affect cancer-fighting immune cells." Read more: http://www.dailymail.co.uk/health/article-4874174/Why-never-hit-snooze-button.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5266) AMAZING - This Smoothie Deflates Your Belly, Cleans The Colon And Will Make You Lose Weight!!
Date:
July 10, 2017 12:14 PM
This is a video about a smoothie that will deflate your stomach and help you lose weight. The video begins with a brief and simple explanation of the human digestive system and describes how food is broken down when consumed. The video then lists the ingredients and preparation method for the smoothie which includes oats, honey, papaya, and cinnamon mixed together in a blender and served cold. The video claims that this mixture will clean out the colon and help a person lose weight. It repeatedly uses the term "deflates the belly" https://www.youtube.com/watch?v=A_o9IbOkrfQ&rel=0Key Takeaways:
"swollen belly's are do to the food we carry and because of our slow digestive system."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4950) Ask the Expert: Are all fats bad for me?
Date:
July 04, 2017 04:14 PM
A dietician addresses the subject of dietary fats. She presents a balanced and objective perspective of these fats, evaluating them by type and their effect on health. This includes a brief overview of some of the body's uses for fat. Healthy unsaturated fats are listed by type and food source, followed by discussion of unhealthy saturated fats, and the food sources where these fats can be found. In conclusion it is stated that including the right kind of fat in the diet is important to human health, but the high caloric content must be taken into account when consuming this food. Key Takeaways:
"Fats are one of three macronutrients (alongside protein and carbohydrates) that are essential to a balanced diet." Read more: http://www.dailyprogress.com/lifestyles/ask-the-expert-are-all-fats-bad-for-me/article_205ffa28-5de4-11e7-ade2-d38adc5084a8.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4926) Drink Ginger Tea And Watch What Happens To Your Body!
Date:
June 23, 2017 05:14 AM
Have you spent your life searching for that perfect superfood or delicious recipe that is both good for a healthy body and good for a healthy mind? Well this video has the solution: ginger, and specifically ginger tea. This video will brief you on the nutritional value of ginger, its many benefits for your body and mind, and even provide you with a recipe that you can try at home. Enjoy this wonderful and tasty solution to all your problems! https://www.youtube.com/watch?v=WU6dGCCC19A&rel=0Key Takeaways:
"It is well known that ginger is good for your health, but also ginger is very good for your brain."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4864) What is the science behind anti-inflammation diets?
Date:
June 12, 2017 07:14 AM
Inflammatory bowl disease is a common factor that is affecting many people and their livelihood. This article briefly outlines the condition and identified specific ways in which inflammatory bowl syndrome affects people. For instance identifying food that cause and release pathogens in the body. Rather than turn to conventional pharmaceutical drugs and medication, people can shift their diets to effectively overcome inflammatory bowl syndrome. In this article, the Mediterranean diet is listed as a great diet alternative There are several tips like adding more whole grains, adding vitamin K, omega 3 fatty acids, and many more to reduce inflammatory bowel syndrome. Read more: What is the science behind anti-inflammation diets?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4816) This Plant Surely Has It In Your Yard And Could Save The Life More Than Once!!
Date:
June 11, 2017 12:14 PM
the video spoke about the money plant or crassula, as it is actuallythe named, and the wonderful medicinal properties that it has. it went into detail about several medical conditions a person might have such as, arthritis, tonsillitis, and ulcers,and the proper way to apply the crassula to treat it. lastly it mentioned a warning against digesting too much of the crassula orally as it has a high amount of arsenic so treatments should be brief and not prolonged. the information was presented in scrolling text and recited verbally by and automated female voice as the text moved. https://www.youtube.com/watch?v=33jmTeuMgLM&rel=0Key Takeaways:
"Having plants in our home is something very beautiful because thanks to our plants the air is purified."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4812) The 8 Most Important CBD Studies Ever Published
Date:
May 28, 2017 04:14 PM
A marijuana advocacy blog has a story listing the eight most significant CBD studies to date. The story states that CBD studies are easier to conduct because the substance does not have psychoactive properties. The studies cover topics such as effectiveness in treating seizures, anti-inflammatory properties, and pain relief. Each discussion is accompanied by a color photo along with an embedded link to the actual study. A brief description of the writer is contained at the end of the feature. There were no comments. Key Takeaways:
"And that’s beneficial because research continues to show the central role CBD plays in the medical benefits of cannabis." Read more: https://www.greenrushdaily.com/2017/05/07/important-cbd-studies/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4717) Named the most important vitamins for healthy teeth
Date:
May 27, 2017 04:14 PM
This is, in essence, a list of vitamins and minerals needed for healthy teeth and gums.It lists vitamins and minerals, a brief description for how the body uses them and various symptoms when they are absent and/or in deficient amounts. Also included within this list are numerous sources where the vitamins and minerals in question can be found. The list is brief yet makes for a good reference and also includes various links to related articles which is helpful. Key Takeaways:
"According to the American Academy of General dentistry, a deficiency of a certain vitamin or mineral can cause problems with oral health." Read more: http://micetimes.asia/named-the-most-important-vitamins-for-healthy-teeth/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4709) HERE'S THE BIGGEST FAT BURNING OF ALL TIME. 40 POUNDS IN A MONTH!!
Date:
March 23, 2017 11:44 AM
There is a natural way to lose weight and stay healthy. This video describes a lemon and chia shake designed for just this purpose. The items are inexpensive and effective. A brief recipe is provided and a description of how to prepare the drink is also given. It is recommended that the beverage be consumed in the morning to take advantage of its benefits. The clip goes on to list the benefits such as vitamins and its toxin eliminating properties. https://www.youtube.com/watch?v=xiWk6Ka6yqA&rel=0Key Takeaways:
"Since ancient times, nature has been the main source of medicine for humans."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4269) nasal polyps treatment miracle
Date:
March 16, 2017 11:59 AM
A mechanical voice presented an advertising video regarding a natural way to get rid of nasal polyps. The video is not a moving picture but just a drawing of a woman injecting something into her nose and an audio description of an offer to tell the viewer how to naturally get rid of the polyps with diet and exercise along with the undisclosed remedy. A link is included to order the briefly described remedy, along with a written testimonial from the vendor and other purchasers. https://www.youtube.com/watch?v=rcqtadzoiu4&rel=0Key Takeaways:
"Firm believer of natural remedy and this guide will combat all painful ailment."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4174) How To Gain Weight | Remedies To Gain Weight
Date:
March 15, 2017 11:14 AM
The video briefly mentions the dangers of being underweight and then talks about home remedies for gaining weight. Specifically, detailed instructions and demonstrations are given for the creation of two weight gain aids. Then it explains the reasons mangoes work well for this task and suggests mango shakes, but does not demonstrate. Then it advises one to eat bananas at breakfast along with warm milk with sugar. The video then does several more recipe demos, interrupted only by a suggestion to eat raisins. https://www.youtube.com/watch?v=1zgIdfa9C7UKey Takeaways:
"It is very important to take proper steps to increase your weight, proper diet and exercise help you to gain weight."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4159) A powerful new form of medical marijuana, without the high
Date:
January 15, 2017 02:59 PM
A new and powerful form of medical marijuana has been discovered, and it will help relieve any ailments you may be having without giving you the “high” effect that many types of marijuana tend to give. This form of marijuana contains cannabidiol, or CBD, not THC, which gives the high effect. Scientists have determined that it can help cure illnesses such as anxiety, heart disease, and cancer. While there is still more research still needs to be done, scientists are hopeful that these findings will help patients shift away from using marijuana with THC. Key Takeaways:
"Many were brief, a half-minute of staring into space, but he also had severe episodes in which he would collapse, sometimes injuring himself." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3787) Avoid Diabetes With This Killer Vitamin!
Date:
November 20, 2016 10:04 AM
Diabetes is a health condition affecting many people. It oftentimes causes disruption in day to day life and the things that the person affected once loved so greatly. But, what would you say if you could take one vitamin every day and ward off the risks of developing this health condition? You might need to prepare your statement now. Key Takeaways:
"Living and working indoors and eating unhealthy diets have contributed to a global epidemic of vitamin D deficiency." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3475) Maca Root And Your Health
Date:
September 28, 2016 07:50 AM
Maca, (Lepidium meyenii) also Peruvian herb is a biennial herb indigenous to Andes, Peru. It’s also grown in Brazil and Bolivia. It’s cultivated for its fleshy hypocotyl and tap root which is a root vegetable and a medicinal herb.
brief history For over 2000 years, Maca root has been used by the ancient Incan culture for medicinal uses. They highly revered the plant for its legendary ability to offer mental clarity and energy as well as enhancing sex drive.
Today, Maca root is medicinal and health benefits such as:
Maca root and Energy improvement
Maca contains vitamins, fatty acids, proteins, and minerals. These are elements to naturally support energy supporting as well as aid in injury recovery. Those who have used maca root in powder form have testified that it makes them awake, driven and energized. They even prefer it over caffeine as it doesn’t give jitters.
Clinical studies have revealed that maca is useful in maintaining positive energy levels and reducing anxiety and depression. It’s also important in regulating the hypothalamus, which improves the functioning of pituitary glands and thus balancing focus and energy. Researchers believe this is enhanced by balancing blood sugar levels. Maca root holds many health benefits, if you are over the age of 50, you should be taking maca root daily to help balance hormones and feel better.
Reference URLs
https://draxe.com/top-5-maca-root-benefits-and-nutrition/
//www.globalhealingcenter.com/natural-health/7-benefits-of-maca-root-for-women/
//www.webmd.com/sex-relationships/guide/the-truth-about-maca
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3316) Adaptogens: Herbs That Can Help In Fighting Stress
Date:
September 06, 2015 09:13 PM
It has been proven through various researches that cortisol hormone in your body can cause stress by effecting its physiological system like adrenal glands or thyroid, etc. The anxiety and irritation caused by the elevation of cortisol can cause a number of health problems including diabetes, weight gain, depletion of energy level and risk of heart problems etc. Most researchers have found adaptogenic herbs as the best and effective natural source of fighting stress caused by the elevation of cortisol in the body. A group of plants that can be used for fighting stress caused by the increase of cortisol hormone in the body are known as Adaptogens. They can help in protecting and restoring the body by balancing its hormonal growth. Some of the popular herbs used for this purpose may include Ashwagandha, American Ginseng, Astragalus, Asian Ginseng, Eleuthero, Cordyceps, Maca, Holy Basil, Schisandra and Rhodiola. Here's a brief description about these herbs: Ashwaganda: It is also known as Indian ginseng as Ayurvedic medicine science uses it since thousands of years not only for fighting stress but also for regulating your immune system by lowering the level of cortisol hormone. American Ginseng: This adaptogenic herb is also known as Panax Ginseng as it belongs to the botanical family of Panax. Normally two types of Ginseng are used for relieving stress including American and Asian ginseng. Asian Ginseng: Researches have proved it to be one of the most popular adaptogens that can help in improving your ability to handle stress along with your mental performance due to its antidepressant and antioxidant properties which can lower the levels of your blood sugar and blood pressure. Though American and Asian ginsengs belong to the same medicinal group, their healing properties are different from each other. Astragalus: The root of this herb is used in various Chinese medicine to reduce the effect of stress along with boosting your immunity level. It can reduce the receptor binding ability of cortisol, a stress causing hormone. Eleuthero: It reduces the symptoms of adrenal fatigue due to its Panax Ginseng like properties. It soothes the stimulated adrenal glands producing stress causing hormones cortisol and adrenaline. Cordycep: It is a kind of fungus which has antioxidant properties to help you in fighting stress along with boosting your immune system. Maca: It is a root vegetable that is used to reduce the risk of various health problems like arthritis and diabetes etc. caused due to increased stress along with increasing your libido. Along with wide variety of nutrients, it also provides healthy fiber to your body. Holy basil: Tulsi is another popular name of this adaptogenic herb. Along with boosting your immune system it also helps you in fighting stress and regulating blood pressure. Schizandra: The berries of this adaptogenic herb are used for making various stress relieving medicines and general tonics in China. Rhodiola: According to various health experts it helps in reducing physical fatigue along with stress related problems like mental stress etc. due to its antioxidant properties. References //www.natural-health-and-healing-4u.com/adaptogenic-herbs.html //draxe.com/7-adaptogen-herbs-to-lower-cortisol //bottomlinehealth.com/maca-the-super-food-that-helps-with-everything-from-fatigue-to-sex-drive
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3211) Why Zinc is Important for the Body
Date:
December 21, 2013 01:39 AM
Zinc Zinc is an important trace mineral found in our bodies. Its importance cannot be underestimated for its lack would cause vital body functions to come to a stop.The amount of zinc found in our bodies is about 3 to 4 grams. Zinc is also known to help people escape dangerous diseases like acne, Alzheimer's and many others. Below is a brief account of the various vital functions of zinc: Zinc enables vital body functions to occur.This is because it stimulates over a 100 enzymes in the body. Enzymes are known to aid in body processes including such activities as making vital body components or helping break down chemicals that the body does not need or would rather harm it, if left to accumulate. Still in enzymatic functions, zinc plays a role in the formation of DNA, bones and breakdown of the proteins we eat. Zinc is very vital when it comes to protecting our bodies against infections. It achieves this function in a multiplicity of ways, the very first being the pivotal role it plays in the healing of wounds. Zinc is also found in body secretions that kill bacteria and viruses which may find their way into our bodies. This is made possible by the fact that it has anti-microbial effects. Zinc is also known to assist in protecting our cell membranes from the harmful effects of metals such as copper and iron. Another similar function of zinc is its ability to assist the liver form an antioxidant known as super-peroxide that assists in elimination of harmful toxins that would otherwise harm the body. Zinc will also help reduce poor night vision for it will slow ocular degeneration.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2934) What Health Benefits Does Dandelion Root Tea Posses?
Date:
January 31, 2013 12:55 PM
Just what are the health benefits of dandelion root tea? Clearly it makes sense to know how it can benefit your body before you think about taking any, so what follows is a brief overview of how this particular natural ingredient can improve your general health.
First, it is full of various minerals and vitamins with the main ones being vitamins A, B complex, C, and D as well as high levels of iron, potassium, and zinc. Clearly your body is going to benefit by having these vitamins and minerals as it does help boost your immune system, but this is not the only way in which it can help your body.
Instead, it is also very well known for helping with various digestive ailments including helping to settle an upset stomach and also to help encourage the appetite after illness. Medical studies have also shown that it can act as a mild laxative as well as boosting the health bacteria that lives in your gut with this playing a key role in keeping your digestive system in check. Finally, it is worth mentioning that dandelion root tea is a fantastic natural detoxifier due to the fact that it does have some diuretic properties, which does of course mean that it can make you urinate more than you are used to. By getting you to urinate more it helps to flush out both your kidneys and liver as it has been shown to improve the overall flow of bile from your liver and clearly this will then benefit your body and it is also believed that it can ease some of the side effects caused by medication that has to be processed by the liver resulting in you feeling better after taking it. Those are just some of the main health benefits of taking dandelion root tea and it is clear that you will only be able to benefit from doing so with there being no need to worry about any side effects at any point. It is healthy and it makes a good drink, so look at giving it a go and see how your body feels from doing so.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2823) What Is the Life Span Of Human Cells And How Do Antioxidants Help?
Date:
August 25, 2011 10:38 AM
The human body is composed of many different cells. These cells have varying functions as well as life span. The human cells, in general, are very complex. Some cells may last only within a day while others may be for life. Like for example, one blood component known as neutrophil lasts only within 24 hours. On the other hand, another blood component which is red blood cell has a life span of 120 days. One human cell which lasts for a lifetime is the stem cell. Stem cells are undifferentiated cells which are the source of blood cells. They supply the body throughout life both with red and white blood cells. Here is a brief outline of some cells of the human body with their corresponding life spans. 1. Granulocytes such as eosinophils, basophils and neutrophils – half day to 3 days 2. Stomach and colon lining cells – 2 to 4 days 3. Sperm cells – 2 to 3 days 4. Epithelial cells of the small intestines – 5 to 7 days 5. Platelets – 10 days 6. Skin epidermal cells – 14 to 28 days 7. Lymphocytes, macrophages and endothelial cells – 2 months to a year, but may vary 8. Pancreatic cells – a year or more 9. Bone cells – 25 to 30 years As shown above, these human cells have an expected time of death. However, if the body is exposed to harmful toxins, their life span significantly decreases. As we know for a fact, the body undergoes many biological reactions almost every second. The reaction is called oxidation process which is essential to the body. However, such reaction has harmful by – products in the form of free radicals. Free radicals can cause the body significant damage. Free radicals can cause destruction and death of the healthy cells of the body and also affect the body’s cellular division. This kind of chemicals can potentially tamper DNA replication during cell division. Once cellular division is tampered, abnormal growths would likely happen. Aside from the naturally occurring free radicals, external stressors can also cause damage to the cells of the body. Some of these include pollutants, harmful chemicals and irritants. These harmful chemicals can potentially lead to the development of certain disease conditions such as heart diseases, stroke and cancer. Fortunately, there are many antioxidants which can greatly help in the prevention of free radical damage by protecting the cells of the body. Antioxidants are molecules which can effectively prevent the oxidation of other molecules. There are many natural antioxidants found among plants and animals. Some common antioxidants are glutathione, vitamin C and vitamin E. Other nutrients which have antioxidative property include beta – carotene, lutein, lycopene, vitamin A and selenium. Fruits and vegetables are great sources of antioxidants. Nuts, grains, meat, poultry products and fish are also good sources of such cell – protecting chemicals. In addition, dietary supplements of antioxidants are also widely available in the market. However, health experts highly suggest that before supplementation of antioxidants, medical evaluation must be done first to be completely safe.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2407) The Krebs Cycle - Our Lifes Blood!
Date:
January 13, 2011 05:00 PM
The Krebs Cycle, also known as the Citric Acid Cycle, is an important series of biochemical reactions that are intrinsic to cellular respiration and the generation of energy from oxygen and glucose in aerobic organisms. Although humans can generate energy anaerobically, they cannot do so for long periods and oxygen is essential for life because it fuels the Krebs Cycle. Without this cycle, there would be no available energy to maintain our vital processes.
What is The Krebs CycleWe shall first discuss exactly what the Krebs Cycle is and then its importance in the body. The process takes place within the mitochondria of the body cells. A. The cycle begins with the ten-step pathway of glycolysis, during which glucose is converted to two molecules of pyruvate: no oxygen is required for this step. Basically: Glucose + 2NAD+ + 2P + 2ADP = 2Pyruvate + 2NADH + 2H+ + 2ATP The pyruvate can then undergo aerobic or anaerobic respiration to generate energy. The Krebs Cycle is the aerobic route, and significantly more efficient that the alternative fermentation. B. The two pyruvate molecules are then oxidized to two of Acetyl CoA with the release of carbon dioxide. The two acetyl groups of the Acetyl CoA are donated to Oxaloacetate in the presence of water to form Citrate. C. Citrate then undergoes a number of chemical reactions to arrive back at Oxaloacetate again and the cycle starts all over again by reacting with more Acetyl CoA from Pyruvate and oxygen to form Citrate again. During the cycle more ATP is produced and electrons and other species are sent into the Electron Transfer Chain where most energy is generated. During this cycle three major events occur: 1. During the various transformations of Citrate, specifically when Succinyl-CoA is converted to Succinate, one Guanosine Triphosphate group (GTP) is generated, which then donates a phosphate to Adenosine Diphosphate (ADP) to create the energy molecule Adenosine Triphosphate (ATP). 2. Over the whole cycle, three molecules of Nicotinamide Adenine Dinucleotide (NAD) are reduced to NADH that donates its electrons to the electron transport chain that is responsible for the generation of large quantities of ATP. 3. A molecule of Flavine Adenosine Dinucleotide (FAD) is reduced to FADH2, again donating its electrons to the electron transport system and the generation of energy. Factor 2 and 3 are of more significance to energy generation than factor 1, and are the major means by which the Krebs Cycle generates energy. Electron Transport Chain The Krebs Cycle takes place within the mitochondria, structures that are contained in each of your body cells. Also within these mitochondria are a series of membranes that are very important in the generation of energy. The major energy produced in your body cells comes from the Electron Transport Chain, a series of chemical reactions between an electron donor and an electron acceptor. Such reactions drive the transport of hydrogen ions (H+) across the membranes in the mitochondria. The electron donors are species such as NADH, FADH2 and succinate and the electron acceptors are oxygen molecules. Hence the importance of oxygen in the process of aerobic respiration. The H+ ions are driven across the membranes and result in the conversion of ADP to ATP energy. In essence, the hydrogen atoms and electrons take part in a progressive chain of redox reactions, and at the end react with oxygen molecules and change it to water. The Ultimate Products Ultimately, through the whole chain and cycles of: Glucose to pyruvate (glycolysis) Pyruvate to Acetyl CoA + CO2 (oxidation) Acetyl CoA to Citrate and the entire Krebs Cycle (reduction and oxidation) Krebs Cycle products to the Electron Transfer Chain Electron Transfer Chain to Water and ATP (redox) Final oxidation of hydrogen atoms to water Basically: Glucose + Oxygen + 30ADP = Carbon Dioxide + Water + 30ATP This is not balanced of course, and the ATP could be anything from 29 to 38, though 29.85 is the most accurate calculation to date. The entire process of glycolysis, oxidation, Krebs Cycle and Electron Transport Chain is powered by a series of enzymes and a small amount of ATP energy. Glucose and oxygen are used up as the raw materials and ATP energy molecules are the product. It has been calculated that the total ATP yield obtained from one molecule of glucose lies between 29.5 and 30 molecules of ATP. The Importance of the Krebs Cycle to Your Body Were it not for the Krebs Cycle you would not be able to generate energy efficiently from your food. In particular, the carbohydrate content of your food. Carbohydrates are available in your diet from two sources: simple and complex carbohydrate foodstuffs such as cereals and grains, and fats and oils from animal and vegetable sources. They are also available from proteins, which are composed of amino acids at the head of the molecule with a carbohydrate tail. Carbohydrates by definition contain only carbon, hydrogen and oxygen molecules, and can be converted to glucose within your body. Proteins can be deaminated and then the carbohydrate portion again converted to glucose. In fact, your body will initially use the carbohydrates in your diet as a source of glucose for its glycolysis to pyruvate, then the fatty tissue in your body, then the proteins will be deaminated so your body can get to the carbohydrate they contain. Were it not for the Krebs Cycle, your body could not use the glucose as described above to generate energy. The only option open to it would be anaerobic respiration, or energy production in the absence of oxygen. ATP is still generated, but much less efficiently. Anaerobic Respiration Anaerobic respiration is basically respiration without oxygen. If there was no Krebs Cycle, then this is the only way your body would have to create energy. Because no oxygen is actually needed for glycolysis or the Krebs Cycle, anaerobic respiration can proceed right to the end of the Electron Transport Chain. Then instead of oxygen being used as the terminal electron donor, it has to be another species such as nitrate or sulfate. Because the Reduction Potential of these species is much lower than that of oxygen, the amount of ATP energy produced is also much lower. Your body tries to compensate by producing even more pyruvate and the excess is removed through lactic acid fermentation. Although this also generates ATP energy enough for short-term use, it leads ultimately to lactic acidosis and a reduction in pH, causing pain and vomiting. Ultimately, if oxygen is not forthcoming, the brain runs short of the energy needed for it to work and you die. There is insufficient ATP generated from anaerobic respiration to maintain human life. Conclusion The Krebs Cycle is of critical importance for the production of energy: not just the energy to enable you to run fast, but to enable your metabolic processes to continue. It is needed for both aerobic and anaerobic respiration, and while lactic acid fermentation can be used by your muscle cells as a brief but effective means of generating short-term energy, it is insufficient to maintain the needs of your metabolism. Without the Krebs Cycle, mammalian and most other animal life would not be viable and the world would be populated by anaerobic bacteria.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2217) Supreme Court Refused Ephedra Appeal…
Date:
May 17, 2007 01:39 PM
Supreme Court Refused Ephedra Appeal…The U.S. Supreme Court on Monday refused to consider an appeal by Nutraceutical International Corporation, which sought to overturn a federal ban on the dietary supplements containing ephedrine alkaloids. The court’s decision, issued without comment, lets stand a 2005 ruling by a federal appeals court that upheld the Food and Drug Administration’s (FDA) 2004 ban. David Seckman, executive director and CEO of the Natural Products Association commented on the refusal. “Obviously we were concerned about the consequences of the circuit court’s ruling on the risk benefit standard the FDA used in removing ephedra from the market, which is why we filed our amicus brief. As we clearly stated in the brief, we believe congress did not intend for such a standard to be used. But, since the Supreme Court decides to take up only between five and ten percent of cases brought to it, it is not a shock that they’ve decided not to hear it. We should note, however, that the denial of the Nutraceutical petition is not an affirmation by the Supreme Court that they agree with the lower court’s decision,” Seckman said. In April, the Natural Products Association had filed a “friend of the court” or amicus brief with the U.S. Supreme Court that challenged the lower court ruling on the standard used by the FDA to impose a 2004 ban on ephedrine alkaloids in dietary supplements.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1538) Memory And Focus
Date:
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Like
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Conclusion
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1533) Learn about Bone Health!
Date:
April 20, 2007 12:43 PM
Bone Health Approximately 44 million American women and men aged 50 and older have osteoporosis (severe bone loss) or osteopenia (mild bone loss), with women being affected about twice as often as men. At least 1.5 million fractures of the hip, vertebra (back or neck), or wrist occur each year in the United States as a result of osteoporosis, and the annual cost of treating this disorder is nearly $14 billion and rising. Unfortunately, the toll in human suffering and loss of independence is even greater. In this issue of Ask the Doctor, we will discuss the risk factors for osteoporosis and some key nutrients you can add to your diet that can minimize bone loss and reduce your chances of developing this disease. Q. What are the risk factors for osteoporosis? A. Small body frame, underweight, Caucasian or Asian race, a sedentary lifestyle, cigarette smoking, excessive alcohol or caffeine intake, high intake of carbonated beverages (especially colas), and having other family members with osteoporosis all increase personal risk of developing the disease. Certain medical conditions, including diabetes, celiac disease, hyperthyroidism, rheumatoid arthritis, chronic obstructive lung disease, hyperadrenalism, and hyperparathyroidism, are all associated with an increased risk of osteoporosis. Some medications increase the rate at which bone is lost; these include drugs prescribed for the treatment of seizures, drugs used for blood thinning, steroids such as prednisone, aluminum-containing antacids, and loop diuretics (furosemide {Lasix}). Q. Isn’t bone loss just a normal consequence of aging? A. Although bone mass normally declines after the age of 35, bone loss severe enough to cause fractures after just minor trauma (such as bump or fall) seems to be a relatively new phenomenon. Osteoporosis was rare in the late 19th century, and it was not until around 1920 that the condition began to attract attention among doctors. Since that time, the percentage of people who develop osteoporosis has continued to increase. For example, the age-adjusted prevalence of osteoporosis in Q. Can osteoporosis be prevented? A. Engaging in regular weight bearing exercise, avoiding excessive consumption of alcohol and caffeine, and quitting smoking will slow the rate of bone loss. Eating adequate, but not excessive, amounts of protein also enhances bone health. In addition, a growing body of research has shown that supplementing with various vitamins and minerals may not only help prevent, but in some cases actually reverse, bone loss. At least 15 different nutrients have been found to play a role in bone health. Q. What type of calcium is best? A. For most people, calcium salts are absorbed about the same, between 30% and 40% of the administered dose. People who low stomach acid (hypochlorhydria) should not use calcium carbonate, because that form of calcium is absorbed poorly in the absence of stomach acid. Calcium phosphate may be preferable for many older people, because phosphorus is necessary for normal bone formation, the phosphorus intake of older people is often low, and calcium supplements inhibit the absorption of phosphorus. Also, calcium bound to phosphorus is the form in which calcium in the bone is stored, and it has a much greater bone activity than other forms. Q. How much vitamin D is needed to promote strong bones? A. Because vitamin D is produced when the ultraviolet rays from the sun hit skin, people who stay out of the sun, wear sunscreen, or live in a northern latitude (such as Boston or Seattle) where less ultraviolet light reaches the skin, are at increased risk of vitamin D deficiency. In addition, aging decreases a person’s ability to synthesize vitamin D in the skin. Results from five research trials on vitamin D found that supplementation with 700-800 IU of vitamin D per day decreased the number of hip fractures by 26%, but 400 IU per day was ineffective. In addition to enhancing bone health, vitamin D improves nerve and muscle function in older people, thereby reducing their chances of falling down. Supplementation of elderly women with 800 IU of vitamin D per day has been shown to decrease the number of falls by about 50%. Q. Is that much vitamin D safe? A. The Food and Nutrition Board of the Q. Why would nutrients besides calcium and vitamin D is important? A. Bone is living tissue, constantly remodeling itself and engaging in numerous biological functions. Like other tissues in the body, bone has a wide range of nutritional needs. The typical refined and processed American diet has been depleted of many different vitamins and minerals, some of which play a key role in promoting bone health. Not getting enough of one or more of these micronutrients may be and important contributing factor to the modern epidemic of osteoporosis. In addition, supplementing with calcium may cause a loss of magnesium, zinc, silicon, manganese, and phosphorus, unless these nutrients are also provided. Q. What nutrients besides calcium and vitamin D promote healthy bones? A. Magnesium, zinc, copper, manganese, vitamin K, boron, strontium, silicon, folic acid, vitamin B6, vitamin B12, phosphorus, and vitamin C have all been shown to play a role in bone health. Following is a brief description of the role that each of these 15 nutrients play in building healthy bones. Calcium: A component of the mineral crystals that make up bone. Vitamin D: Enhances calcium absorption, prevents falls by improving nerve and muscle function. Magnesium: Important for bone mineralization (accumulation of minerals which form bones). Magnesium deficiency is associated with abnormal bone mineral crystals in humans. In an open clinical trial, magnesium supplementation increased bone mineral density by an average 5% after 1-2 years in postmenopausal women. Copper: Laboratory research has found that copper promotes bone mineralization and decreases bone loss, and that osteoporosis can develop if the diet is deficient in copper. Western diets often contain less copper than the amount recommended by the National Academy of Sciences. In a 2-year double-blind trail, copper supplementation reduced bone loss by 90% in middle-aged women, compared with a placebo. Zinc: Like magnesium, zinc is important for bone mineralization, and also has been shown to decrease bone loss. Low dietary zinc intake was associated with increased fracture risk in a study of middle-aged and elderly men. The zinc content of the diet is frequently low; a study of elderly low-income people found they were consuming only half the Recommended Dietary Allowance for this mineral. Manganese: Plays a role in the creation of the connective-tissue components of bone. Manganese deficiency in laboratory tests resulted in low bone mineral density and weak bones. Manganese deficiency may be associated with the development of osteoporosis. Boron: Supports creation of bone-protecting hormones such as estrogen, testosterone, and DHEA. Boron supplementation prevented bone loss in experimental studies. In human volunteers consuming a low-boron diet, boron supplementation decreased urinary calcium excretion by 25-33%, a change that may indicate reduced bone loss. Silicon: Plays a role in the synthesis of the connective-tissue components of bone. Silicon deficiency has been associated with bone abnormalities. In an observational study, higher dietary silicon intake correlated with higher bone mineral density. In a clinical trial, administration of an organic silicon compound increased bone mineral density of the femur (or thigh bone) in postmenopausal women. B vitamins (folic acid, vitamin B6, and vitamin B12): These three B vitamins have been shown to lower blood levels of homocysteine, a breakdown product of the amino acid methionine. An elevated homocysteine concentration is a strong and independent risk factor for fractures in older men and women. Homocysteine levels increase around the time of menopause, which may explain in part why bone loss accelerates at that time. In a 2-year double-blind trial, supplementation of elderly stroke patients with folic acid and vitamin B12 reduced the number of hip fractures by 78%, compared with a placebo. Strontium: This trace mineral is incorporated into bone and appears to increase bone strength. It also stimulates bone formation and inhibits bone breakdown. Controlled trials have demonstrated that strontium supplementation of postmenopausal women increases bone mineral density and decreases fracture risk. Vitamin K: Best known for its effect on blood clotting, vitamin K is also required for the creation of osteocalcin, a unique protein found in bone that participates in the mineralization process. The amount of vitamin K needed for optimal bone health appears to be greater than the amount needed to prevent bleeding. Vitamin K levels tend to be low in people with osteoporosis. In randomized clinical trials, supplementation of postmenopausal women with vitamin K prevented bone loss and reduced the incidence of fractures. Q. Which form of vitamin K is best? A. Two forms of vitamin K compounds are present in food: vitamin K1 and vitamin K2. Vitamin K1 (also called phylloquinone) is present in leafy green vegetables and some vegetable oils, and vitamin K2 is found in much smaller amounts in meat, cheese, eggs, and natto (fermented soybeans). To make things a little more complicated, Vitamin K2 itself can occur in more than one form. The two most important to this discussion are menaquinine-4 (MK-4, also called menatetrenone), which is licensed as a prescription drug in Research suggests that MK-7 from natto may be an ideal form of vitamin K. The biological activity of MK-7 in laboratory studies was 17 times higher than that of vitamin K1 and 130 times higher than that of MK-4. After oral administration, MK-7 was better absorbed and persisted in the body longer, compared with MK-4 and vitamin K1. Although both have shown ability to prevent osteoporosis in laboratory research, a much lower dosage (600 times lower) of MK-7 is required, compared to MK-4, to obtain beneficial effects. Thus, MK-7 has greater biological activity, greater bioavailability, and possibly more potent effects on bone, compared with other forms of vitamin K. The potential value of MK-7 for bone health is supported by an observational study from Q. Why is strontium so important in building strong bones? A. Strontium is of great interest to bone health researchers and has been studied in very high doses. Surprisingly, lower doses are not only safer for long-term supplementation, but may in fact have a greater impact on bone health than very high doses. Too little, and bone density is impaired; too much and health may be impaired. This is a case where dosing needs to be just right for optimal impact. Therefore, until more is known, it is wise to keep supplemental strontium at less than 6 mg per day. Q. Can people taking osteoporosis medications also take bone-building nutrients? A. Because nutrients work by a different mechanism than osteoporosis drugs, nutritional supplements are likely to enhance the beneficial effect of these medications. Calcium or other minerals may interfere with the absorption of biphophonates such as alendronate (Fosamax) or etidronate (Didronel). For that reason, calcium and other minerals should be taken at least two hours before or two hours after these medications. Also, it is always best to discuss the supplements you are using with your healthcare practitioner to create an integrated health plan. Final thoughts… Bone health ramifications extend beyond osteoporosis and fractures. Bone health is essential for freedom of movement, safety, comfort, independence and longevity. Weak bones do not heal well – sometimes they never heal at all. Osteoporosis-related fractures rob us of our mobility and consign thousands of Americans to walkers and wheelchairs every year. In fact, 40% of people are unable to walk independently after a hip fracture, and 60% still require assistance a year later. The most terrible consequence of fractures related to osteoporosis is mortality. The impairment of the ability to move around freely can cause pneumonia and skin damage leading to serious infections. It is estimated that suffering a hip fracture increases the risk of dying almost 25%. Making bone health a priority now will allow you to reap health dividends for many years to come.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1523) Peppermint Oil for IBS
Date:
March 24, 2007 11:01 AM
Irritable bowel syndrome (IBS) is a painful and frequently frustrating disorder of the intestines that’s often difficult to treat. Fortunately, there are scientifically studied natural products that effectively reduce the distressing symptoms of IBS. Q. What is IBS? A. IBS causes crampy pain, gassiness, bloating, and alterations in bowel habits. IBS is termed a functional disorder, because when the colon is examined, there is no visible sign of disease. While IBS causes significant pain and distress, no actual damage is occurring in the intestines. There is a wide variability in IBS. Symptoms may be mild and fairly well tolerated. Or, the pain, discomfort, and bowel dysfunction may be disabling, limiting social interactions, employment, or travel.
While some individuals with IBS have diarrhea (frequent, loose stools with an urgent need to move the bowels), others have constipation (hard, infrequent stools that are difficult to pass). And, still others may experience both. Individuals with IBS also may have painful abdominal cramps and feel an urgent need to move the bowels, but are unable to do so. A. The small intestine receives digestive material from the stomach and delivers it to the large intestine (colon). About two quarts (2,000 ml) of digestive material enter the colon from the small intestine every day. The colon absorbs water and salts from the material, which is progressively moved through the colon. This progressive movement continues until most of the fluid and salts are absorbed into the body and stool is formed. The stool passes to the left side of the colon, where it is stored until a bowel movement occurs. Because researchers haven’t been able to find actual damage in the colon, it once was suggested that individuals with IBS have emotional problems or are overly susceptible to stress. While stress may cause symptoms of IBS to intensify, it doesn’t cause the condition. Recent study has determined the colon muscle of an individual with IBS spasms after only mild stimulation. It’s thought the symptoms of IBS are produced by hyperactivity of the intestines. In other words, the intestines of individuals with IBS are more reactive to stressors and diet than usual. Almost everyone has experienced abdominal queasiness in response to everyday stress or certain foods. This may result in a brief bout of diarrhea or an upset stomach. However, this response is exaggerated in individuals with IBS. Q. How prevalent is IBS?
A. IBS is very common. In fact, it’s one of the most frequent problems seen by family physicians. It’s the most common disorder diagnosed by gastroenterologists (physicians specializing in the treatment of digestive disorders). The overall prevalence rates range from 10% to 20% of the general population in most industrialized countries. As a result, the pain and disabling symptoms associated with IBS result in significant socioeconomic costs, as wall as reduction in quality of life for many individuals. A. Normal bowel function varies from person to person. Some people move their bowels daily, while others may only have two to three stools a week. A normal bowel movement is soft, formed, and is easily passed without cramping or pain. IBS, however, causes abdominal cramps and pain, which are often severe and disabling. Bowel movements may be irregular and alternate between diarrhea and constipation. The diarrhea may be quite loose and watery. Mucous may be passed. There is often much straining, urgency, and feeling of incomplete evacuation (emptying). Abdominal bloating and passing of gas is common. Nausea, lack of appetite, heartburn, and belching may also be present. Sleep may be disrupted resulting in fatigue and lack of energy. Understandably, persons with IBS often feel anxious and depressed. Diagnosis of IBS is usually based on the continuous presence or recurrence of these symptoms for at least three months. Other intestinal conditions must be ruled out. These include Chron’s disease, ulcerative colitis, inflammatory bowel disease, colon cancer, inflammatory conditions of the stomach or pancreas, ulcers, infectious disease, or gastroesphageal reflux disease. Q. Are there clinically demonstrated natural alternatives to the over-the-counter drugs prescribed by my doctor? A. Yes, both enteric-coated peppermint oil and clown’s mustard (in combination with other herbs) have significant scientific research behind them. Both have been demonstrated to benefit individuals with IBS. Q. What is clown’s mustard and what does it do? A. The scientific name for clown’s mustard is Iberis amara. Other names for this herb are wild candytuft and bitter candytuft. Clown’s mustard is a white-flowering plant from Spain, where it grows in dry soil on hillsides and in cornfields. It is also grown in Britain, France, and the United States. Iberis amara is a member of the Brassicaceae family. Iberis refers to its place of origin, the Iberian Peninsula. Amara means bitter. The key components of clown’s mustard are glycosides and flavonoids that have specific actions on gastrointestinal tract tone. Q. Is there scientific evidence that clown’s mustard benefits people with IBS? A. There has been very impressive research on clown’s mustard (in combination with other herbs). And, it has been used with great success in Germany for many years to treat IBS and other gastrointestinal diseases. In a study of an herbal combination containing clown’s mustard, 20 patients were given the herbal combination for three to 32 days. They all had been diagnosed with chronic functional disorders for at least one to 20 years. The symptoms the patients experienced included pressure and pain in the abdomen, belching, heartburn, vomiting, nausea, fullness, lack of appetite, constipation, and diarrhea. The patients have been treated for their problems with a variety of antacids, anti-spasmodic agents, and motility-inducing substances. For the purposes of the study, the patients stopped taking these medications and received treatment only with the herbal combination. Abdominal pressure and pain in the abdomen was the most common of all the experienced symptoms, with 11 of the patients rating it as severe. After six days of treatment, only sic of the patients continued to rate their abdominal pain and pressure as severe. After two weeks, this symptom had completely resolved for 16 of the patients. Diarrhea had been rated as severe in five of the patients. By day 14, only one patient continued to have moderate diarrhea. Medications prescribed and taken for cardiovascular diseases, arthritis, and autoimmune diseases often cause gastrointestinal problems. Because these conditions are chronic, these medications must be taken for a long time, often for life. With long-term use, these medications can cause erosion of the stomach lining and actual ulcers. Many of these medication-caused symptoms are similar to IBS symptoms: pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Most, if not all, of the individuals who have gastrointestinal problems caused from medications experience two or more of these IBS symptoms. Forty patients who were taking medications for various types of cardiovascular disease and arthritis, and who are experiencing gastrointestinal problems related to their medications, were enrolled in a study. These symptoms included pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Twenty patients received clown’s mustard combined with other herbs that support gastrointestinal motility. Three days after the trial started, a significant improvement of all s symptoms was noted in those taking this combination. By day 14, abdominal pressure and pain, nausea, and heartburn were completely eliminated in the herbal combination group. Several other clinical trials that were conducted in Germany report similar results. Q. How does this herb compare to prescription drugs? A. A study compared clown’s mustard (combined with other herbs) to Reglan (metoclopramide), which is frequently prescribed to reduce the symptoms of IBS. While metoclopramide is a very effective medication, it also has numerous side effects. Metoclopramide can cause fatigue, anxiety, agitation, jitteriness, insomnia, yellowing of the skin or eyes, changes in vision, hallucinations, and seizures. Because of these serious side effects, metoclopramide must not be taken longer than 12 weeks. In comparison study, 77 subjects were randomized to receive treatment of either clown’s mustard in a combination with other herbs, or metoclopramide. All subjects had pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. The subjects took 20 drops of their assigned treatment after meals three times daily. The duration of treatment was one to two weeks. In both groups, a parallel improvement of all symptoms was observed. At no point in the study was a statistically significant difference in symptoms found. Both treatments significantly reduced pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. In short, both metoclopramide and the clown’s mustard herbal combination worked well at reducing the symptoms of IBS.
However, side effects occurred more frequently and severely in the metoclopramide group. Given the lack of differences noted between the products at reducing symptoms of IBS, it would seem sensible to choose the treatment with the fewest reported side effects and no limits on duration of use. A. Peppermint oil has been shown to relax intestinal smooth muscle. In Great Britain, peppermint oil is currently being prescribed for IBS by physicians and it has been used as a digestive aid and to soothe upset stomachs for generations. Peppermint oil has also been studied for use in an important examination of the colon. A colonoscopy is a procedure of viewing the interior lining of the large intestine (colon) using a colonoscope, a slender, flexible, hollow, lighted tube about the thickness of a finger. A study published in the New England Journal of Medicine supports the idea that even people who are not at risk for colon cancer should have this test. The American Cancer Society recommends that men and women at average risk of colon cancer should have a colonoscopy every 10 years, beginning at age 50. During a colonoscopy, individuals are sedated and almost no discomfort is experienced. The insertion of the colonoscope into the rectum and up through the colon causes some spasming. This is a natural and expected event and the physician performing the exam administers medications that effectively reduce the spasms. A recent study compared the use of peppermint oil and commonly used medications to reduce the colonic spasming in colonoscopy. The peppermint oil was introduced directly into the colon. Effective reduction of colon spasming was observed in 88% of the patients. In a critical review and meta-analysis of peppermint oil for irritable bowel syndrome published in The American Journal of Gastroenterology, eight randomized controlled trials were identified. The studies collectively showed peppermint oil is superior to placebo in improvement of the symptoms of IBS. Because of the good results of these trials, the authors of the review urged additional study of peppermint oil in IBS. However, straight peppermint oil is rapidly absorbed into the blood stream from the stomach. In recent studies comparing enteric-coated peppermint oil capsules and non-enteric coated oil, both preparations provided effective symptom relief. However, the studies concluded the enteric-coated capsules delivered the benefit of the peppermint oil directly to the intestines. In the treatment of IBS, enteric-coated supplemental peppermint is most definitely preferred. In fact, an enteric-coated peppermint oil capsule containing rosemary and thyme is extremely effective in the treatment of IBS. All three of these oils are classified as volatile oils, derivatives found in plants that impart taste and aroma. The combination of peppermint, thyme, and rosemary oils in enteric-coated capsules provides significant relief in IBS-related pain. Q. Can clown’s mustard and other herbs be taken with enteric-coated peppermint oil? A. Yes, peppermint oil capsules and clown’s mustard can be used together. However, depending on the symptoms, individuals with IBS may want to start with one supplement and then add the other if needed. Q. How do consumers find these formulas? A. Fortunately, herbal combinations containing clown’s mustard and enteric-coated peppermint oil capsules are both available at health food stores, natural product supermarkets, pharmacies, and from health professionals. Most knowledgeable sales personnel and health professionals can direct consumers to the most effective products. Q. What should customers look for when purchasing peppermint oil? A. As mentioned before, enteric coating of the peppermint oil is extremely important. The coating prevents the oil from being absorbed in the stomach. The enteric coated-capsule moves through the stomach to the small intestine and eventually to the colon, where it is released for maximum benefit. Q. What is the dosage for peppermint oil? A. The German Commission E approved peppermint oil for the treatment of irritable colon. In enteric-coated form, the Commission E recommends 0.6 ml per day. Enteric-coated peppermint capsules are available. Q. Are there side effects or other contraindications? A. Sometimes, the enteric-coated peppermint oil capsules may cause a transient burning sensation in the rectum when moving bowls. Reducing the dose will correct this. Individuals who must refrain from alcohol should not take clown’s mustard in an herbal tincture, which may contain alcohol. Q. What else can IBS patients do to feel better? A. Food allergies or food intolerance may be associated with IBS. Dairy products and certain grains may trigger a painful episode of IBS. Determining those foods that initiate the problems and eliminating them from your diet can be very helpful. Many people report their symptoms occur after a meal. Hyperactivity of the intestine of IBS is the response. Often, the strength of this response after a meal is in direct relation to the number of calories and he amount of fat in the meal. Reducing saturated fat, limiting calories, and increasing fiber intake may be helpful. Stress also stimulates the intestinal hyperactivity. Relaxation training may reduce some IBS symptoms. Listening to therapeutic audiotapes, hypnosis, counseling, and biofeedback all have been shown to improve the healing response in persons with IBS. Conclusion IBS can be painful and frustrating, capable of causing much distress. While currently there is no cure for IBS, the symptoms can be managed. The pain, abdominal discomfort, and bowel problems of IBS all respond well to treatment with the use of key herbs, including clown’s mustard, and enteric-coated peppermint oil. These herbal combinations can be both effective and safe in treating IBS. Clown’s mustard and enteric-coated peppermint oil are both effective front-line natural alternatives for IBS treatment.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1494) Ola Loa Multi-Vitamin Mineral Formula
Date:
February 22, 2006 06:33 PM
Ola LoaLets face it. Most people don’t look forward to taking their daily vitamins. Its too complicated; there are too many pills and capsules. You take some with food, some with out. Forget to eat this morning? Put your pills in your pocket and carry them with you to take at lunch or dinner or tomorrow? With Ola Loa’s single serving packs, getting your daily multi is not only convenient and delicious, but also based on sound nutrition science. That’s the Ola Loa Advantage! In formulating Ola Loa, Richard Kunin M.D. chose its powerful combination of vitamins, minerals and amino acids based on their functional uses in the body and his 40 years of scientific research and experience giving nutrients to his patients. Nowhere will you find a more strategic and effective collection of nutrients. Ola Loa Energy formula includes NAC, and Vitamin C (which strengthens antioxidant and immune function), along with six amino acids, CoQ10, and 40 mineral complexes. Ola Loa provides you with enough TMG to lower homocysteine and raise SAME levels. Ola Loa’s nutrients and pleasing taste have almost instant benefits. You will feel a difference. Ola Loa REPAIR is a great tasting effervescent multi-vitamin powder that provides unparalleled nutrient support for bones, joints, cartilage and the aches and pains of everyday life. REPAIR is recommended for daily bone and joint health, as a general anti-aging vitamin and is a comfort to those concerned about bone health and regular wear-and-tear on joints. Our convenient grab-and-go packs are easy to bring with you wherever you go. Just pack Ola Loa for your business or pleasure trips or throw a few packets in your brief case, purse or desk drawer. Having Ola Loa around encourages regular vitamin consumption and will give you that boost of nutrients whenever, wherever you need it.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1226) Court Rules for FDA in Lane Labs Appeal
Date:
December 12, 2005 09:44 AM
A federal appeals court has ruled that Lane Labs (Allendale,NJ) may be ordered to pay back consumers for selling what the food and drug administration (FDA) considered unapproved new drugs. The three-judge panel upheld the 2004 decision by U.S. district Judge William G. Bassler of the District of New Jersey, which stated that FDA may demand that Lane Labs pay back every consumer who had bought the company’s top selling products—shark cartilage supplements that were allegedly marketed as treatments for diseases including cancer and HIV. The restitution amount is estimated at 109 million. The appeals court rejected the argument that FDA cannot demand restrictions because the Federal Food, Drug, & Cosmetic Act (FDCA) does not expressly provide for such a remedy. “Whether or not congress specifically contemplated restitution under the FDCA, the ability to order this remedy is within the broad equitable power granted to the district courts to further the economic protection purposes of the statute,” 3rd Circuit Judge Marjorie O. Rendell wrote in an opinion joined by Judges Maryanne Trump Barry and Edward R. Becker. In its appeal, Lane Labs was supported by an amicus brief from the Washington Legal Foundation (WLF, Washington, DC) urging the court to reverse Bassler’s decision, on the grounds that restitution is not authorized anywhere in the text of the FDCA. WLF attorneys Daniel J. Popeo and Richard A. Samp, joined by attorney Jeffrey A Lamken of Baker Botts in Washington, DC, argued that the FDCA gives courts the power to “restrain” violations, but does not allow FDA to seek “Backward-looking monetary relief.” WLF argued that FDA, throughout most of its history, never asserted a right to seek restitution until recently, when it began asserting that power in order to have “a big club with which to intimidate manufacturers who might otherwise seek to challenge FDA directives,” including large pharmaceutical companies. However, the court upheld FDA’s authority to seek restitution on the grounds that the FDCA’s grant of authority to restrain violations of the Act should be read broadly to include all forms of equitable relief. FDA cannot be allowed to get away with this power grab,” said Samp after reviewing the Third Circuit’s decision. “The American economy suffers, and public safety and health are jeopardized, when FDA seeks to exert power beyond its authority, upsetting to delicate balance struck by Congress in its attempt to both preserve the public welfare and encourage valuable pharmaceutical innovations.” He added that WLF has pledged to continue to litigate the issue and to support Lane Labs in any further appeals the company may file.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1011) The wellness Revolution - 90% Of Americans Carry Chemical Stew in their Bodies.
Date:
October 01, 2005 01:22 PM
The Wellness Revolution90% of Americans Carry Chemical Stew in their Bodies The third national report on human exposure to Environmental Chemicals, issued this summer, shows that most people in the U.S., and especially children, carry a dangerous mixture of chemicals in their bodies. Nevertheless, the Center for Disease Control (CDC), authors of the report, issued a press release focusing on progress made in a few areas—and most media looked no further than the optimistic press release. The CDC sampled the blood and urine of thousands of subjects across the country for 148 environmental chemicals. This study found a significant decline since previous reports in exposure to secondhand smoke and in lead levels in children’s blood. Despite the positive headlines, however, the study documented the presence in human bodies of dozens of pesticides and toxic compounds used in consumer products. Among the findings: Body Burden and the wellness Revolution This Study—the latest indication that all of us carry a “body burden” caused by widespread chemical use in our society—shows the need for a system that relies on organic agriculture and alternative pest controls. The constant exposure to toxics we experience today is a major cause of chronic illness, including cancer, birth defects or abnormal development, brain or nervous system damage, hormonal and reproductive imbalances, and impaired immunity, to name just a few. Meanwhile, individuals should take advantage of the organic products available in health food stores, and the herbs and nutrients that support detoxification and the liver, the main organ of detoxification, as well as immunity—for example, silymarin, N-acetyl cysteine, calcium d-glucarate, folic acid, Reishi and shiitake mushroom, and turmeric. A healthy lifestyle and appropriate supplementation can offer some protection from societal pollution. Sources: Third National Report on Human Exposure to environmental Chemicals, 2005, available at www.cdc.gov. Los Angeles Times, 7/22/05. A brief Companion to CDC’s 2005 National Exposure Report, Physicians for Social Responsibility, www.psr.org. Pesticide action network, www.panna.org.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=805) Curcumin - Turmeric Extract
Date:
August 19, 2005 12:47 PM
Turmeric- History and Traditional Usage
Native to Southeast Asia, Curcuma longa is a tall
In addition to its
Turmeric is named in
Protects cells and tissues by fighting free radicals.* Supports joint function*
The numerous beneficial
Curcumin demonstrates Animal studies- In vivo protective effects
Through its free radical scavenging Human Trials
Curcumin exhibits free-radical scavenging ability when
Bioperine-Nature’s Absorption Enhancer
Traditional Ayurvedic herbal
Curcumin is poorly absorbed in the intestinal Scientific References
© 2002 *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=734) STEVIA (Stevia rebaudiana)
Date:
July 15, 2005 12:24 PM
STEVIA (Stevia rebaudiana) SYNONYMS: sweet herb, honey leaf PARTS USED: leaves Description Stevia is a small perennial shrub with green leaves that belongs to the aster (Asteraceae) or chrysanthemum family of plants. They grow primarily in the Amambay mountain range of Paraguay but over 200 various species of stevia have been identified around the globe. Stevia rebaudiana is the only species at present which possesses an inordinate ability to sweeten. Its common form is known as stevioside, a fine white powder extracted from the leaves of the plant. Phytochemistry STEVIOSIDE/REBAUDIDOSIDE COMPOUND DUO: The leaves of the stevia shrub contain specific glycosides which produce a sweet taste but have no caloric value. Stevioside is the primary glycoside involved in this effect. Dulcoside and rebaudioside are also major glycosides contained in the herb. Glycosides are organic compounds which contain a sugar component (glycone) and a non-sugar component (aglycone). The glycone constituent may be comprised of rhamnose, fructose, glucose, xylose, arabinose etc. The other portion may be any kind of chemical compound such as a sterol, tannin, carotenoid, etc. Stevia leaves also contain protein, fibers, carbohydrates, phosphorus, iron, calcium, potassium, sodium , magnesium, rutin (flavonoid), iron, zinc, vitamin C and vitamin A. Human physiology cannot metabolize the sweet glycosides contained in stevia leaves, therefore they are eliminated from the body with no caloric absorption. Stevia, unlike aspartame, can be used in baking because its sweet glycosides do not break down when heated. Definition Stevia is an herb with incredible sweetening power. Its ability to sweeten is rated between 70 to 400 times that of white sugar. Typically, it has a mild licorice-like taste and is completely natural in its biochemical profile. What makes stevia so intriguing is that unlike other natural sweetening agents, its is completely calorie-free, never initiates a rise in blood sugar, and does not provide “food” for microorganisms like bacterias and yeasts. Stevia may well be the most remarkable sweetener in the world and yet its recognition in this country remains relatively low. Consider the extraordinary attributes of the stevia plant and its extracts:
A brief History Stevia is a plant indigenous to mountainous regions of Brazil and Paraguay. For centuries, this herbal sweetener has been used by native cultures to counteract the bitter taste of various plant-based medicines and beverages. The Guarani Indians of Paraguay have used this potent sweetener in their green tea for generations. The name they designated for stevia leaves was “sweet herb.” In addition, these native peoples have historically used stevia as a digestive aid and a topical dressing for wounds and other skin disorders. In the sixteenth century, Europeans became aware of the herbal sweetener through the Spanish Conquistadors. In the late 1880s, Moises S. Bertoni, director of the College of Agriculture in Asunción, Paraguay, became extremely intrigued by the stevia plant. Its reputation was that it was so sweet that even just a small leaf part could sweeten an entire container of mate tea. Be rtoni wanted to find out if this was true. After several years of studying the plant, he wrote about it in a local botanical publication. In 1905, Bertoni published an important article about the incredible sweetening power of the stevia plant, which he considered superior to sugar and extremely marketable. Other articles written by Bertoni note that stevia is unquestionably superior to saccharine because it is nontoxic and has significant therapeutic benefits. It sweetens with unprecedented potency and can be used in its natural state. The first stevia crop was harvested in 1908 and subsequently, stevia plantations sprang up in South America. In 1921, the American Trade Commissioner to Paraguay, George S. Brady, wrote that although the herb is an extraordinary sweetener with remarkable properties, little had been done to commercially cultivate the plant. He suggested that stevia may be an ideal sugar product for diabetics and strongly advised that American companies pursue its importation. During the decade of the 1970s, the Japanese developed a new method which could better refine the glycosides contained in the stevia leaf. The result was a compound called ste-vioside which is from 200 to 300 times sweeter than white sugar. The Japanese approach artificial sweeteners with great caution and they believe stevioside to be safer and more effect i've than other non-nutritive, chemical products. Stevioside is considered superior in its ability to sweeten; however, it does not exhibit some of the other therapeutic actions found in whole stevia leaves . Stevia enjoyed substantial popularity during the 1980s as a natural sweetener and was found in a variety of consumer products. In 1986, however, the FDA abruptly seized stevia inventories and in 1991 claimed it was not suitable as a food additive. Advocates for stevia claim this happened because the herb is a natural, powerful, inexpensive and non-patentable sweetener, and therefore poses a threat to pharmaceutical sweeteners and sugar-alcohol sweeteners like mannitol, sorbitol and xylitol. At this writing, stevia has received approval by the FDA to be sold only as a dietary supplement, not as a sweetening agent. Currently, stevia is commercially grown in Paraguay, Brazil, Uruguay, Central America, Israel, China, Thailand, and the United States. It is considered an important natural sweetener in both Japan and Korea, and has been safely used in these countries for decades. Extracts of stevia and related products make up a considerable portion of the Japanese market for natural sweetening agents. They use stevia in sweet sauces, pickles, beverages, etc., making Japan one of the largest single consumers of stevia in the world. Today, because the demand for stevia is escalating, several Paraguayan organizations are looking to expand the commercial cultivation of the plant. Currently, Canadian researchers and chemists are working to provide even better stevia supplements and may even end up teeming with governmental agencies to raise stevia crops as economic replacements for tobacco leaves (Bonvie, 64). Stevia has not been officially approved by Canadian agencies, but it is still available for purchase in tea form.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=639) REFERENCES
Date:
June 25, 2005 08:13 PM
REFERENCES 1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. 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Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. 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In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=507) CHITOSAN: The Fiber that Binds Fat
Date:
June 25, 2005 07:55 PM
Overview Chitosan is a natural product that inhibits fat absorption. It has the potential to revolutionize the process of losing weight and by so doing, reduce the incidence of some of the most devastating Western diseases we face today. Chitosan is indigestable and non-absorbable. Fats bound to chitosan become nonabsorbable thereby negating their caloric value. Chitosan-bound fat leaves the intestinal tract having never entered the bloodstream. Chitosan is remarkable in that it has the abilty to absorb an average of 4 to 5 times its weight in fat.60 The same features that allow chitosan to bind fats endow it with many other valuable properties that work to promote health and prevent disease. Chitosan is a remarkable substance whose time has come.
Chitin, the precursor to Chitosan, was first discovered in mushrooms by the French professor Henri Braconnot in 1811.61 In the 1820’s chitin was also isolated from insects.62 Chitin is an extremely long chain of N-acetyl-D-glucoseamine
FIGURE 2. glucoseamine units. Chitin is the most abundant natural fiber next to cellulose and is similar to cellulose in many respects. The most abundant source of chitin is in the shells of shellfish such as crab and shrimp. The worldwide shellfish harvest is estimated to be able to supply 50,000 tons of chitin annually.63 The harvest in the United States alone could produce over 15,000 tons of chitin each year.64 Chitin has a wide range of uses but that is the subject of another book. Chitosan was discovered in 1859 by Professor C. Rouget.65 It is made by cooking chitin in alkali, much like the process for making natural soaps. After it
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---------------------------------- is cooked the links of the chitosan chain are made up of glucosamine units. Each glucosamine unit contains a free amino group. These groups can take on a positive charge which gives chitosan its amazing properties. The stucture of chitosan is represented schematically in Figure 2. Research on the uses of chitin and Chitosan flourished in the 1930s and early 1940s but the rise of synthetic fibers, like the rise of synthetic medicines, overshadowed the interest in natural products. Interest in natural products, including chitin and chitosan, gained a resurgence in the 1970s and has continued to expand ever since. Uses of Chit osan Some of Chitosan's major uses—both Industrial and Health and Nutritional—are listed in Tables 5 and 6. Water Purification Chitosan has been used for about three decades in water purification processes. 67 When chitosan is spread over oil spills it holds the oil mass together making it easier to clean up the spill. Water purification plants throughout the world use chitosan to remove oils, grease, heavy metals, and fine particulate matter that cause turbidity in waste water streams. Fat Binding/ Weight Loss Like some plant fibers, chitosan is not digestible; therefore it has no caloric value. No matter how much chitosan you ingest, its calorie count remains at
------------------------------ fibers, chitosan’s unique properties give it the ability to significantly bind fat, acting like a “fat sponge” in the digestive tract. Table 7 shows a comparison of chitosan and other natural fibers and their ability to inhibit fat absorption. Under optimal conditions, Chitosan can bind an average of 4 to 5 times its weight with all the lipid aggregates tested.60 (NOTE: This assessment was made without the addition of ascorbic acid which potentiates this action even further.77 Studies in Helsinki have shown that individuals taking chitosan lost an average of 8 percent of their body weight in a 4-week period.76 Chitosan has increased oil-holding capacity over other fibers.108 Among the abundant natural fibers, chitosan is unique. This uniqueness is a result of chitosan’s amino groups which make it an acid absorbing (basic) fiber. Most natural fibers are neutral or acidic. Table 7 summarizes the in vivo effects in animals of various fibers on fecal lipid excretion. As can be seen from the results listed, ingestion of chitosan resulted in 5-10 times more fat excretion than any other fiber tested. D-Glucosamine, the building block of chitosan, is not able to increase fecal fat excretion. This is due to the fact that glucosamine is about 97 percent absorbed while chitosan is nonabsorbable. Fats bound to glucosamine would likely be readily absorbed along with the glucosamine. Chitosan, on the other hand, is not absorbed and therefore fats bound to chitosan can not be absorbed. Cholesterol Control Chitosan has the very unique ability to lower LDL cholesterol (the bad kind) while boosting HDL cholesterol (the good kind).78 Laboratory tests performed on rats showed that “chitosan depresses serum and liver cholesterol levels in cholesterol- fed rats without affecting performance, organ weight or the nature of the feces.”79 Japanese researchers have concluded that Chitosan “appears to be an effective hypocholesterolemic agent.”80 In other words, it can effectively lower blood serum cholesterol levels with no apparent side effects. A study reported in the American Journal of Clinical Nutrition found that Chitosan is as effective in mammals as cholestryramine (a cholesterol lowering drug) in controlling blood serum cholesterol without the deleterious side effects typical of cholestryramine. 81 Chitosan decreased blood cholesterol levels by 66.2 percent.82 It effectively lowered cholesterol absorption more than guar gum or cellulose.83 Laboratory test results indicated that a 7.5% chitosan formula maintained adequate cholesterol levels in rats, despite a dramatic increase in the intake of cholesterol. 84
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Date:
May 13, 2005 08:38 AM
Sulforaphane Stimulates the Body's Cancer-Fighting EnzymesSecret Weapon Against Cancer Found in Broccoli Sproutsby Richard Conant, L.Ac, C.N. The health benefits of vegetables were known historically, long before researchers began seeing a connection between vegetable consumption and cancer prevention. Over the last twenty years, evidence concerning this connection has steadily accumulated. The latest and most promising findings reveal that specific vegetable constituents—"phytochemicals" to use current scientific parlance— enhance the body's defenses against cancer. This article will focus on one phytochemical in particular, a sulfur-containing compound called "sulforaphane." Found in Cruciferous vegetables such as broccoli, sulforaphane may prove to be one of our most powerful cancer prevention allies. Recent studies have shown that sulforaphane stimulates, or "induces," "Phase two enzymes." These enzymes are an integral part of the body's elaborate detoxification system that renders carcinogens inactive. This detoxification system turns carcinogens and other toxic substances into harmless molecules that are excreted from the body. We need not fear carcinogens—the body is equipped to deal with them. These findings, coupled with an appreciation of the body's ability to defend itself against carcinogens, have the potential to dramatically change the way we look at cancer and substances in the environment that "cause" cancer. We need to minimize unnecessary exposure to carcinogens, and the staggering quantity of hazardous chemicals in the environment remains an urgent health concern, for cancer and many other health problems. But, knowing the body is equipped with the means to defend itself against toxins, we do not need to fear carcinogens as perhaps we have in the past.
The natural world is full of carcinogens. What's more, even if you eat 100 percent organic food and live in a environment free of toxic man-made chemicals, you are still being exposed to carcinogens every day of your life. Food is the primary route of this exposure. Plants, for their own defense, produce over 99% of all the pesticides in agricultural products.1 Almost all foods—in their natural state—contain tiny amounts of naturally-occurring, potentially carcinogenic chemicals. The point is not to trivialize the concern over environmental toxins. The point is that the natural world is full of toxins that are not man-made. These substances have been around since before we appeared, which is why we have evolved with a highly efficient system for neutralizing them before they can damage our cells and initiate the complex process that produces cancer. Broccoli sprouts are a concentrated source of cancer-fighting sulforaphane. We cannot avoid carcinogens. What we can do is support our internal detoxification system. Sulforaphane is a powerful tool in this effort. We can start by following the often-repeated advice to eat a variety of vegetables every day, and include broccoli in our menu. There is an even richer source of sulforaphane than broccoli itself. In September 1997, a group of scientists at the Johns Hopkins University School of Medicine made a breakthrough discovery— broccoli sprouts contain ten to one hundred times more sulforaphane than mature broccoli.2 Vegetable sprouts are generally regarded as exceptionally healthy foods. Broccoli sprouts now look like a shining star, especially when it comes to cancer prevention. For those lacking the time or inclination to keep a fresh supply of broccoli sprouts on hand, broccoli spouts have been processed into an extract that is even more concentrated in sulforaphane. More on this later. What have researchers learned about broccoli consumption and cancer rates? More than 200 epidemiological studies—studies which track groups of people over time to uncover realtionships between variables such as diet and the incidence of disease—have invesitgated the connections between vegetable consumption and various forms of cancer.1 It should be understood that findings from epidemiological research are generally not regarded as conclusive; these studies are not controlled, and often use data gleaned from questionnaires, which are an imprecise method of gathering information. (In the case of diet questionnaires, for example, the study subjects may or may not record their food intakes with 100 percent accuracy.) Epidemiological studies look for trends. To be credible, these trends need to show up consistently, in different population groups. Findings from the vegetable intake/cancer studies easily meet these criteria; the number of studies is large and the trend is consistent—vegetable consumption is strongly associated with a lower risk of developing cancer. What about broccoli in particular? A paper published in the September 1996 issue of Cancer Epidemiology, Biomarkers & Prevention analyzes epidemiological data gathered from 94 studies concerning the cancer preventive effect of brassica vegetables.3 (The Brassica genus, part of the Cruciferae family, includes broccoli, cabbage, kale, cauliflower and brussels sprouts.) The data suggest that broccoli consumption reduces the risk of some of the most feared forms of cancer, including stomach and lung cancer. Now, to put these data into a balanced perspective, the researchers point out that in most of the studies reviewed, brassica vegetable consumption was reported as part of the total vegetable intake. "In hardly any epidemiological studies was the effect of brassica vegetables separated from the effect of total vegetables or other vegetables by adjusting for consumption of these variables. Therefore, it is difficult to sort out whether the observed observation was attributable to brassica vegetables, to vegetables as a whole, or to other vegetables," they noted. This uncertainty is a good example of why epidemiological studies alone do not give us open and shut conclusions. But the paper also adds that the apparent anti-cancer effect of brassica vegetables agrees with "the results of experimental studies in which brassica vegetables reduced mammary tumor incidence, hepatic tumor size, numbers of tumors per liver, tumor frequency, and the number of pulmonary metastases when given to rodents before or after a carcinogen insult."3 When you put together a plausible trend from epidemiological research with results of experimental studies that agree with the trend, and then add additional research that reveals the underlying mechanism for these observations, a clear picture begins to take shape. And, indeed, we now have a fairly good idea as to just how brassica vegetables, especially broccoli, help prevent cancer. How sulforaphane helps prevent cancer from developing. To see how sulforaphane works, let's look at a brief overview of the body's detoxification system. The detoxification of carcinogens and other toxic substances takes place in the liver, and involves two distinct enzyme-driven processes or "phases". Phase one enzymes neutralize toxins by various routes. Some of these convert toxins into substances that are immediately eliminated. However, other Phase one steps convert toxins into intermediate products which are carcinogenic themselves, and require further treatment before they can be excreted. Phase two enzymes do this vital job. Phase two enzymes deactivate these carcinogenic metabolites of Phase one, and the final breakdown product is then eliminated once and for all. (For an excellent review of this subject, see Encyclopedia of Natural Medicine, by Drs. Michael Murray and Joseph Pizzorno.4) Phase two is critical. If Phase one is in good working order, but Phase two is not, the potential threat from carcinogens increases. It is vitally important to keep Phase two operating well. This is where sulforaphane plays its cancer preventive role. Sulforaphane is a powerful inducer of Phase two enzymes.5,6 Broccoli sprouts-the ideal source of sulforaphane Sulforaphane is one among a group of phytochemicals called "isothiocyanates." (These occur in brassica vegetables largely as "glucosinolates," which are precursors for isothiocyanates2,12 When the plant is crushed, glucosinolates are converted to isothiocyanates.) Sulforaphane induces Phase two enzymes exclusively, leaving Phase one enzymes alone. This means it helps reduce the load of carcinogenic Phase one intermediates without adding to the load by stimulating Phase one.8,9 As reported by the Johns Hopkins University research group, broccoli sprouts are an "exceptionally" rich source of sulforaphane (in the form of "glucoraphanin, sulforaphane's glucosinolate precursor). And broccoli sprouts have another advantage over mature broccoli. They contain almost no indole glucosinolates, phytochemicals present in mature broccoli that "can enhance tumorogenesis."2 Broccoli sprouts as an extract, now available as a dietary supplement, takes the concentration of sulforaphane to the next level. This recently developed nutraceutical product contains a potent 20 to 1 extract of three-day old fresh broccoli sprouts. One 125 mg capsule supplies the same amount of sulforaphane as 125 grams, or about 5 ounces, of mature broccoli. Taking just one capsule a day is like eating two pounds of broccoli per week, which equals the intake of cruciferous vegetables believed necessary to obtain their health benefits. References 1. Steinmetz, K.A. Potter, J.D. Vegetables, fruit, and cancer prevention: A review. J Am Diet Assoc. 1996;96:1027-1039. 2. Fahey, J.W., Zhang, Y., Talalay, P. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc. Natl. Acad. Sci. 1997; 94:10367-10372. 3. Verhoeven, D.T.H., et. al. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiology, Biomarkers & Prevention 1996;5:733-48. 4. Murray, M. Pizzorno, J. Encyclopedia of Natural Medicine. Rocklin, CA: Prima Publishing;1998:110-120. 5. Zhang, Y. Talalay, P, Cho, C., Posner, G.H. A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure. Proc. Natl. Acad. Sci. 1992;89:2399-2403. 6. Gerhäuser, C. et. al. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Research 1997;57:272-78. 7. McDanell, R., McLean, A.E.M., Hanley, A.B., Heaney, R.K., Fenwick, G.R. Chemical and biological properties of indole glucosinolates (glucobrassicins): A review. Fd. Chem. Toxic. 1988;26(1):59-70. 8. Talalay, P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis. in Advances in Enzyme Regulation, Vol. 28, Weber, G., Ed., 1989: Pergamon Press. 9. Prochaska, H.J. Santamaria, A.B., Talalay, P. Rapid detection of enzymes that protect against carcinogens. Proc. Natl. Acad. Sci. 1992;89:2394-98.
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