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  Messages 1-38 from 38 matching the search criteria.
Use warm water and turmeric to cleanse your body, support digestion Darrell Miller 5/10/19
Take Indian kudzu if you're diabetic: It keeps your kidneys healthy VitaNet, LLC Staff 11/10/18
How safe are heartburn medications and who should use them? Darrell Miller 8/11/17
Healthy gut bacteria improve immunity Darrell Miller 7/7/17
This All-Natural Cancer Treatment Is Saving Lives Darrell Miller 4/16/17
Reflux and ulcer medications linked to kidney stones and chronic kidney disease Darrell Miller 12/4/16
Dental Benefits of Xylitol; Protect your teeth against decay. Darrell Miller 10/7/14
Can Pancreatic Enzymes Help Reduce Pancreatic Stress? Darrell Miller 5/22/13
Calcium and magnesium - vital to health Darrell Miller 12/20/12
Why Is Organic Extra Virgin Coconut Oil So Good For Your Health? Darrell Miller 2/23/12
How can I Tell if I am Magnesium Deficient? Darrell Miller 2/9/11
Omega-3 Darrell Miller 7/8/09
Digestive Essentail Enzymes Darrell Miller 1/4/09
EDTA Darrell Miller 1/3/09
What is Hoodia? Darrell Miller 4/8/08
Acai: The Super Antioxidant From Brazil Darrell Miller 2/3/08
Give Your Health A Boost With Silica Hydride A Powerful Antioxidant Darrell Miller 1/18/08
Coconut Oil May Help Promote Healthy Thyroid and Digestive Function Darrell Miller 11/1/07
Benefits - Supports joint function and tissue health* Darrell Miller 12/11/06
Interview on symptoms of Fibromyalgia and one mans story Darrell Miller 8/9/06
The healing power of borage oil Darrell Miller 6/19/06
Lutein to fight age-related macular degeneration! Darrell Miller 2/27/06
Molecularly Distilled Omega-3 fish Oil Fact Sheet Darrell Miller 1/12/06
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Darrell Miller 12/7/05
Source Naturals - Our Commitment to Your Well-Being Darrell Miller 8/20/05
Curcumin - Turmeric Extract Darrell Miller 8/19/05
ST. JOHN’S WORT AND AIDS/HIV Darrell Miller 7/15/05
Bio-Chelation Darrell Miller 6/29/05
Alcohol-Free Herbal Extracts Darrell Miller 6/29/05
Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story Darrell Miller 6/29/05
Well Child - For a Healthy Winter Darrell Miller 6/21/05
Modified Citrus Pectin (MCP) and Mercury Cleansing Programs... Darrell Miller 6/21/05
Go Green - green foods may be the SWAT team that sets you free... Darrell Miller 6/12/05
The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease Darrell Miller 6/9/05
What is Hoodia? Darrell Miller 6/9/05
Mega H- Hydrogen (H-)The Fuel of Life Darrell Miller 6/3/05
Milk Thistle and Liver Damage abstract ... Darrell Miller 5/22/05
Re: Its in the Blood Darrell Miller 5/9/05



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Use warm water and turmeric to cleanse your body, support digestion
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Date: May 10, 2019 02:25 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Use warm water and turmeric to cleanse your body, support digestion





It is estimated that a lot of Americans are affected by digestive problems. Gastroesophageal reflux disease (GERD) alone affects about 20 percent of Americans according to a 2010 estimate and that number should have increased by now. Pharmaceutical products being used to treat these symptoms can do more harm than good. Some of the drugs used for proton pump inhibitors of which 113 million are prescribed every year have been identified as the cause of bone fractures in older women and clostridium infections that result in diarrhea and life threatening conditions in older people. Some natural products though can do the work of cleansing your digestive system without the side effects and also help detox the body. One of them is turmeric. Just add some turmeric in warm water and one is ready to have these benefits. Warm water on its own is very important to the body but when mixed with turmeric it will help create bile that breaks down and absorbs fat in the body. Bile eliminates wastes in the body thereby detoxing your body the natural way.

Key Takeaways:

  • The purview of the NIDDK, otherwise known as the National Institute of Diabetes, Digestive and Kidney Disorders, covers a range of digestive complaints.
  • The large array of digestive specific ailments covered includes pancreatitis, ulcerative colitis, irritable bowel syndrome and much more.
  • Data suggests that proton pump inhibitors, like Nexium, can cause serious long-range side effects.

"Turmeric mixed in a warm glass of water will not only help cleanse your body, but they will also lend support to your digestive system."

Read more: https://www.naturalnews.com/2019-04-03-warm-water-turmeric-to-cleanse-your-body-support-digestion.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6307)


Take Indian kudzu if you're diabetic: It keeps your kidneys healthy
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Date: November 10, 2018 09:51 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Take Indian kudzu if you're diabetic: It keeps your kidneys healthy





Diabetes is a serious and chronic condition, which as it progresses can wreak havoc on an array of bodily systems. One potential victim of the havoc is the kidneys. They endure a great deal of oxidative stress in a body that is constantly fighting the effects of diabetes. This ongoing stress overtime does damage the kidneys and can eventually destroy them The condition of oxidative stress endured by kidneys functioning under an ongoing onslaught of diabetic effects is known as diabetic nephropathy. In a worse case scenario it can lead to total renal failure. The organic tuber, Indian Kudzu, is an Aryuvedic medicine staple, besides housing a wealth of antioxidants. Researchers from a Banaras Hindu University recently decided see whether the oxidative power of Indian Kudzu might be able to stand tall against the stress endured by kidneys undergoing diabetic onslaught, thereby protecting them from the ravages of the stress. The study, which used rodent subjects, proved that though oxidative stress in the diabetic rodent subjects was high, the kudzu was able to reduce or reverse some of the damage, due in part to its ability to improve human antioxidant enzyme activity.

Key Takeaways:

  • Diabetes can have many negative effects, including diabetic nephropathy, which can damage and even destroy the kidneys.
  • The condition is caused by oxidative stress, a state that regular consumption of the Indian Kudzu can help slow down and block, making it an effective adjunct to hypertension protocols.
  • The premise that the Kudzu would prove protective was upheld in a study done at A Banaras Hindu University that made use of rodent subjects.

"The tubers are a treasure trove of antioxidants that reduce the effects of oxidative stress and reactive oxygen species related to aging and various ailments."

Read more: https://www.naturalnews.com/2018-11-06-indian-kudzu-for-diabetics-it-keeps-kidneys-healthy.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5825)


How safe are heartburn medications and who should use them?
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Date: August 11, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How safe are heartburn medications and who should use them?





Heartburn medications that are currently prescribed might not be the most effective in treating heartburn. Many people suffer from heartburn and many of those people are prescribed what is known as "protein pump inhibitors." These medications prevent stomach cells from producing stomach acid, which causes heartburn. However, these medications often need to be taken for long periods of time and may lead to early death. While studies show proton pump inhibitors are effective at reducing heartburn, one study found a small increased risk of early death for those taking these medications and other studies have linked negative side effects, like vitamin B12 deficiency, to proton pump inhibitors. Nevertheless, the benefits outweigh the risks. Yet, it seems as though too many proton pump inhibitors are being prescribed than are necessary. Therefore, only those suffering from extreme heartburn should be prescribed proton pump inhibitors, as they can be very beneficial to treating their condition.

Key Takeaways:

  • Acid reflux is classified in two types, one with clear erosions and non-erosive.
  • Protien pump inhibitor doses of 5 mg a day were effective in significantly improving symptons in non-erosive reflux.
  • Protein pump inhibitors should not be used for extended time periods and only when necessary, as many are over prescribed and used indefinitely.

"A study found these drugs were very effective for treating reflux disease, with eight weeks of therapy with standard (once daily) dosing healing acid damage in more than 80% of patients."

Read more: http://theconversation.com/how-safe-are-heartburn-medications-and-who-should-use-them-80809

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5109)


Healthy gut bacteria improve immunity
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Date: July 07, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Healthy gut bacteria improve immunity





Having healthy gut bacteria improves your overall immunity. The human body has ten times the amount of bacteria than cells do. These bacteria live on the skin and in the mouth and in the intestines. Many people turn to hand sanitizing to solver their problems. But, that can actually do more harm than good if you use a lot of it. There are studies that show no matter how much hand sanitizing you do, you will still have tons of bacteria in you.

Key Takeaways:

  • no matter how much hand sanitizer people use, their bodies are filled with good bacteria and other microbes.
  • Helpful bacteria, viruses, protozoa and fungi that live in the body make up the microbiome which helps us digest food, protect us against disease-causing bacteria and make vitamins.
  • eating fruits and vegetables, limiting processed food, and consuming at least 25 grams of fiber a day can help rebuild good bacteria in the body.

"Consider adding probiotics to the diet, preferably through natural foods rather than supplements."

Read more: http://www.centredaily.com/living/liv-columns-blogs/article159366034.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4938)


This All-Natural Cancer Treatment Is Saving Lives
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Date: April 16, 2017 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: This All-Natural Cancer Treatment Is Saving Lives





The cure for cancer, the most far reaching, and devastating disease known to man, might be found in cannabis. The THC in Marijuana is the potent that gives the stimulated high. There are other benefits for cancer patients who venture into the world of marijuana. There is still much research to be done, however for some cancer patients after consuming cannabis in it's many form has proven to be beneficial. Cancer cells have been stimulated to commit suicide. However every person is different and should consult with their doctor to see if marijuana might be of benefit to negatively stimulate cancer cells.

Key Takeaways:

  • -It’s well known that cannabis can help to alleviate pain and nausea associated with chemotherapy, but can cannabis oil actually kill cancer cells? A number of studies point in that direction, and the
  • -When cancer patients use cannabis oil to inhibit the growth of cancer cells, they often use the Rick Simpson Oil (RSO) Protocol. The method involves consuming 60 grams of cannabis oil over the course
  • -And should you add cannabis or cannabis oil to your treatment plan? Probably. But rely on it completely to cure cancer? Experts say this isn’t a good idea — yet.

"To date, several studies on humans and animals have solidified the link between cannabis compounds and cancer cell death."

Read more: http://www.thealternativedaily.com/cannabis-natural-cancer-treatment/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4417)


Reflux and ulcer medications linked to kidney stones and chronic kidney disease
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Date: December 04, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Reflux and ulcer medications linked to kidney stones and chronic kidney disease





A University in Rome has found information that links medications taken for acid reflux and heartburn to a higher incidence of kidney stones. By reviewing patient files, they found that patients who took PROTOn pump inhibitors were at a 12% higher risk of developing kidney stones throughout their lives, and those who took histamine receptor-2 were at a 13% higher risk. They have stated that more research needs to be done, but any link between the medicine and kidney stones is cause for alarm.

Key Takeaways:

  • "Use of PPIs and H2 blockers is associated with a small increase in risk of incident kidney stones
  • chronic kidney disease that may arise after use of PPIs is secondary to incomplete recovery from acute kidney injury (AKI
  • Reliance on AKI as a marker of potential adverse renal events in those treated with PPI is not sufficient,

"PROTOn pump inhibitors (PPIs) and histamine receptor-2 (H2) blockers are commonly used to reduce gastric acid production."



Reference:

https://www.sciencedaily.com/releases/2016/11/161118130351.htm

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3564)


Dental Benefits of Xylitol; Protect your teeth against decay.
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Date: October 07, 2014 08:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dental Benefits of Xylitol; Protect your teeth against decay.

tooth decayDental Cavity

Tooth decay, mostly affects children and elders, but can affect people of any age. Elders are especially more susceptible to tooth decay because as you grow older, the root surface of the teeth becomes more susceptible to decay. Tooth decay is among the major causes of tooth loss among younger people. Although improper diet and poor oral hygiene are the major causes of the teeth decay, teeth decay is also a degenerative condition that is caused by the breakdown of the enamel. Tooth decay causes destruction of tooth structure that causes development of cavities (development of a hole in the teeth).

Causes of tooth decay

As mentioned earlier, tooth decay is mainly caused by poor dietary choices as well as poor oral hygiene practices. Most foods are rich in starches and sugars. When these foods are left on the teeth, it forms a plaque, which in turn combines with bacteria in the mouth. Plaque Bacteria produces acids that damage the enamel causing tooth decay. Low fluoride and Xerostomia (dry mouth- a condition the body does not produce enough saliva) can also cause tooth decay.

Can Xylitol Really Help Fight Tooth Decay?

Xylitol is a sweet, whitish substance that tastes and looks like sugar, but it contains lower calories than sucrose making it diabetic friendly. It is wholly natural substance found in vegetables and fruit fibers. Xylitol is produced in small amounts by the human body. This product is effective in protecting teeth against decay.

What does it Xylitol do?

Xylitol prevents accumulation of plaque bacteria that causes tooth decay, and promotes growth of tooth protective, non-acidic bacteria. Plaque bacteria mostly use carbohydrates and sucrose from our diet to grow and multiply. The bacteria create a sticky thread that allows it to attach to the surface of the tooth to form thick layer and acidic solution that damages teeth.

When these bacteria absorb Xylitol, they cannot stick to the tooth surface, cannot multiply or produce acid that causes tooth decay.

Eating products like Zellies Xylitol mint and Mints Zellies Gum means less plaque will form on your teeth, and in time plaque, bacteria will be eliminated in your mouth. Xylitol also encourages mineral rich saliva to flow into your mouth, and raises the mouth pH, which discourages the multiplication of plaque bacteria. This can protect and re-mineralize your teeth by repairing the deep layers of the enamel.

Xylitol better for teeth than other sweeteners.

Apart from being diabetic friendly, Xylitol is also better for teeth than other sugarless sweeteners on the market. Xylitol is a 5-carbon alcohol that is very different from other similar sounding sweeteners found in commercial products. Although other sugarless sweeteners may not penetrate the PROTOplasm of plaque bacteria cells, they cannot kill bacteria like Xylitol.

Can I use to treat tooth decay?

No, but it can be confidently used to maintain healthy and protect teeth from decaying. Continuous use of Xylitol will create healthy environments for mouth bacteria and eliminate plaque bacteria. Take 6 grams of Xylitol daily for at least 5 weeks, and the sticky plaque bacteria will be eliminated from your teeth. Go for a test, the plaque bacteria will not be detected in your saliva, on tongue and teeth. In addition, your breath will be fresh.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3161)


Can Pancreatic Enzymes Help Reduce Pancreatic Stress?
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Date: May 22, 2013 10:43 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Pancreatic Enzymes Help Reduce Pancreatic Stress?

Kal: Pancreatin 500ct 1400mg

  Pancreatic enzymes are crucial for the purpose of breaking down fats, carbohydrates and proteins. A healthy pancreas will produce about 8 cups of pancreatic juice daily. This is released into the duodenum helping neutralize any acid. This potion of the stomach is at the entrance of the small intestines. The lack of these fluids could cause a myriad of problems depending on the functions that are carries out.

The question however is; can pancreatic enzymes help reduce pancreatic stress?

One of the best ways to answer this is to find out what these enzymes are and do exactly.

Lipase is a pancreatic enzyme that breaks down fats. The lack of this enzyme causes a shortage of fat soluble vitamins and diarrhea evident by fatty stools.

Protease breaks down proteins in the body. It is also crucial in keeping the system clear of PROTOzoa and yeast among many other parasites. The lack of the same will cause a rise on toxicity in the stomach due to faulty digestion. The individual will also be at risk due to infections.

Amylase will break down carbohydrates and is commonly found in the saliva. The lack of the same will cause diarrhea due to the presence of starch that is undigested in the colon.

This is common in patients that have developed pancreatic cancer. The lack of pancreatic juice in the body will cause pancreatic stress. This calls for doctors to find a way to help induce the functionality of this juice into the body. This is the reason why pancreatic enzymes are used to help along with the breaking down of these body substances.

This partly answers the question, can pancreatic enzymes help increase pancreatic stress?

Some other effects that could come with the lack of these enzymes include cystic fibrosis, pancreatitis, duodenal tumors and Whipple procedure. Some of the symptoms of these conditions brought by the lack of the enzymes include cramps, gas, indigestion, weight loss and diarrhea.

These enzymes given by doctors may also be given along some acid reducing medication. These enzymes should be taken carefully to ensure that they work optimally. 

Added enzymes will ease pancreatic stress by balancing the digestive system. The body in turn will not think it needs more enzymes and reduce its demands on the pancreas.

Some of the things to keep in mind when using these are;

  1. Ensure that you take the enzymes with every meal for digestion to take place optimally.

  2. Start with a small dose and increase depending in the situation. You may need to alter this depending on the progressiveness of the situation.
  3. The enzymes should be taken right before meals. If you are taking a number of the, take some in between the meal, never take them after the meals as they will not function then.
  4. Ensure that you take the capsules and the pills with water or any other liquids. They should not be ingested in the mouth unless under special circumstance and orders from the doctor.

The most common side effect of these enzymes is constipation. They are however the best way to deal with indigestion due to the lack of the pancreatic fluid in the body.  Have you had your pancreatin today to boost digestion and eliminate food allergies?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2842)


Calcium and magnesium - vital to health
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Date: December 20, 2012 02:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium and magnesium - vital to health

Calcium and magnesium are two essential minerals for the body, bringing serious damage if there is a deficiency. Calcium is essential for maintaining bone strength in the body, but also for the functioning of nerve and muscle cells.

Bones perform several roles in the body, but most of us are interested in the preservation of acid-base balance (pH). When the pH of the blood is too acidic , bone alkaline elements released (alkali salts) to neutralize acids. This leads to loss of bone mass (and calcium), while rapidly releasing toxins and heavy metals stored in bone if there are metals and toxins present.

Most of us know that calcium is found in dairy products. True, but the information is not complete. You should know that of all dairy products, yogurt offers the most calcium, about 200 mg in a cup. But if you want the most bioavailable calcium, ie one that is most easily absorbed and can be used fully by the body, then you need to take calcium citrate.

If the food based calcium intake is not optimal and extremely diverse, then you need calcium-based vitamin supplement products. Calcium supplements may be consumed with meals for maximum digestion and absorption. But even if you take dietary supplements, diet should not remain poor, continue to get adequate amounts of calcium from food sources.

Magnesium has an important role in the efficient functioning of the nervous system, muscular system and  enzyme processes in the body. It is necessary for calcium absorption. The ratio of the two minerals is especially important. An adult daily needs for bone health by around 1,500 mg of calcium and 1000 mg of magnesium. Bones are living tissues that rebuild constantly. A healthy diet, exercise, enough sleep (at least 8 hours) and keeping well hydrated with water helps strengthen bones. Calcium and magnesium, combined doubles benefits to our body, especially if they are of citrate in origin. 

Cal-Mag Citrate Why?

Studies have shown that calcium and magnesium citrate is the easiest form to digest with minimal stomach acids. This make it work great for older individuals who have low stomach acids or who are on PROTOn pump inhibitors. 

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2758)


Why Is Organic Extra Virgin Coconut Oil So Good For Your Health?
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Date: February 23, 2012 07:12 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why Is Organic Extra Virgin Coconut Oil So Good For Your Health?

Organic Extra Virgin Coconut Oil

Why Is Organic Extra Virgin Coconut Oil So Good For Your Health?

One of the main reasons why this oil happens to be really good for your health is because it contains a pretty high percentage of lauric acid. According to certain resources, our bodies actually converts lauric acid into some sort of monolaurin, and it's said to help deal with the bacteria and viruses that causes various diseases. Studies have shown that lauric acid helps prevent diseases like HIV, herpes, cytomegalovirus, and influenza. The types of bacteria that this acid fights are heliobacter pylori and listeria monocytogenes. This oil also prevents certain harmful PROTOza's as well.

The Benefits Of Organic Extra Virgin Coconut Oil.

- Weight Loss

Virgin coconut oil is well known for eliminating all of the extra fats that your body has, and according to certain sources, the results can be very visible. Since this oil boosts your metabolism, you will be able to lose more weight than you normally would. The reason to why your metabolism fastens when you consume this oil is because it eliminates the stress on your pancreases, allowing your body to lose more weight than normal. This is basically the main reason why the people that live in tropical countries are fit and have less fat than those who don't, as coconut oil is very easy to get in those tropical countries.

- Hair Care

Virgin coconut oil also helps promote softer, smoother, and much healthier hair, as it is well known for being the best medicine for hair. This oil doesn't just promote healthier hair, but it also helps the hair grow faster, and the best part is that it also eliminates the dandruff in your hair. All you need to do is massage a bit of this oil on your scalp everyday, and in just a couple of days, you'll then notice your dandruff start to disappear.

- Skin Care

This oil is also a really excellent oil (massage) for the skin, as it acts as a natural moisturizer. If you have dry skin, this would make a really great moisturizer for your skin, and the nicest part is that it also helps treat skin conditions like eczema and psoriasis. When you apply this oil on your skin, you will really be shocked on how fine and healthy your skin will become.

Organic Extra virgin coconut oil is also good for stress relief and kidney relief, and it can also maintain the cholesterol levels and increase your immunity. This oil has become very popular lately, and it's definitely going to benefit you in the long run.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2591)


How can I Tell if I am Magnesium Deficient?
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Date: February 09, 2011 01:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How can I Tell if I am Magnesium Deficient?

Magnesium The Essential Mineral

Magnesium is a dietary mineral that has established nutritional values in most countries. The presence of magnesium inside the human body involves many different chemical reactions, assisting more than 300 enzymes in their functional roles. That’s why we need to meet the daily recommended allowances for this dietary element, which has been calculated by the scientific community to supply the body with amounts adequate to support body functions.

An Essential Mineral

Not all enzymes are capable of producing the effects that they are programmed for on their own, and enzymes identified to rely on the presence of magnesium can be traced in almost all metabolic pathways. Molecules that comprise the structural units of RNA and DNA are extensively used as a source of energy of all cells, such as adenosine triphosphate or ATP. When enzymes utilize ATP for energy, they require another molecule that secures their binding to ATP, which is magnesium. In addition, ATP being the main source of energy that powers the functional roles of cells more often than not necessitates that it be bound to a magnesium ion to be fully activated.

Absorption Problems

Magnesium is ubiquitous in nature, and green leafy vegetables are ideal sources of this dietary element as well as nuts, wheat, seafood, and meat. In spite of that, it has been reported that in the US alone more than 60 per cent of the population does not meet the recommended daily intake for magnesium. The availability of magnesium in our diet does not ensure absorption of this essential mineral, and a significant fraction is in fact excreted along with other waste products in the urine or feces. Interestingly, diet high in protein or fat actually interferes with the absorption of magnesium.Solaray - Magnesium Asporotate 180 ct

Magnesium Deficiency

A general feeling of malaise must not be taken lightly, for it is key indicator of magnesium deficiency. Magnesium is indispensable at the cellular level, and insufficient amounts of this element will certainly affect the way you feel, bringing about the perception of fatigue. If you feel weak all the time for no known reason, then it is recommendable to visit your doctor and find out if you have an alarming case of magnesium deficiency.

Keep in mind that high concentrations of protein and fat in the foods that you eat contribute to malabsorption of magnesium, and subsequently malnutrition. Certain medical conditions are known to deplete your reserves of elemental magnesium present in your body, notably diabetes mellitus. Drugs and medications also washes away the magnesium found in your diet and your body especially osmotic diuretics, cisplatin, ciclosporin, amphetamines, and possibly PROTOn pump inhibitors.

Continued exposure to stress and excessive intake of alcohol both result in the unhealthy drop of magnesium levels in the blood. While there are environmental settings that we may not be able to alter, we can certainly control what we ingest. Supplementation is the only surefire remedy for magnesium deficiency, but the best way to combat whatever symptoms you are experiencing is to seek medical advice.

It is Essential You Get Your Magnesium Daily!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2234)


Omega-3
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Date: July 08, 2009 10:50 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3

The headline "Doubts over heart claims of omega-3 fats" was published in March of 2006 in the world's largest international news agency, Reuters. This article reported on the findings of a study on omega-3 fats and heart health, which published the exact same month in the British Medical Journal. The article found in Reuters claimed that the systematic review of 89 studies led to the conclusion that there was no substantive evidence that omega-3 fats actually protected individuals against cardiovascular disease or cancer. The New Zealand Herald picked up this article and announced that the heart-healthy advice to eat more oily fish was incorrect, as it advised its readers to put fish oils on the top of the list of medical beliefs that turned out to be myths.

In actuality, the omega-3 investigation, conducted by Lee Hooper and coworkers at the University of East Anglia School of Medicine, was a meta-analysis, as it combined data from several available clinical trials. Meta-analyses are highly speculative due to the differences in the scientific PROTOcols between the included studies, which can lead to difficulty in exposing a common factor. A good meta-analysis is often useful to put contradictory evidence into perspective. However, a poorly designed analysis can lead to bad science and faulty conclusions.

This Hooper analysis was a review of 48 randomized controlled trials, along with 41 cohort studies. However, the investigation only used as few as 15 controlled trials and 3 cohort studies in compiling the data. Included in this analysis were studies that had very small sample sizes and provided little data on the effects under investigation. Extremely low death rates in several of the studies that were included worsened the situation, which resulted in a very large confidence interval and a lower analytical power than what was expected. Additionally, there was a large degree of difference among the included studies. Some of them had death rates in their control groups as low as 0.5%, while others had extremely high control-group death rates exceeding 15% and 22% in two cases. This fact indicates that there were large disparities in the health of subjects. This much heterogeneity among subjects requires a high degree of analytical power in order to produce meaningful results. This was something that the Hooper study lacked.

When addressing the above issues, the authors of the study pointed out that “there were too few events such as deaths, associated cardiovascular events, and incidences of cancer to rule out the possibility of important effects from various interventions.” This basically means that the numbers produced in the study produced results that didn't show much of anything. In a case like this, a person should be extremely cautious as to dismissing a possibly association based on negative results. Dr. Mike Knapton, the Director of Prevention and Care for the British Heart Foundation cautioned the public that they should not stop consuming omega-3 fats or eating oily fish as a result of this study. The wise advice given by Dr. Knapton, however, was not enough to stop the media from fabricating stories and devaluing the necessity for omega-3 fats.

The fact is that omega-3 when taken on a consistent basis can help reduce cholesterol and improve cardiovascular health. Look for high quality omega-3 fish oil that is molecularly distilled at your local or internet health food store. Always select name brands to ensure quality and purity of the product you purchase.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Omega-3 fish oil is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2029)


Digestive Essentail Enzymes
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Date: January 04, 2009 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Digestive Essentail Enzymes

Years of researching various health-promoting herbs, vitamins, minerals, and other dietary supplements has led to the conclusion that enzyme therapy is one of the most valuable ways to maintain and promote good health. Not very many of us actually understand the enormous role that enzymes play in health maintenance, with many of us actually being enzyme depleted due to the over-consumption of cooked enzyme-less foods and the under-consumption of raw whole foods. The human digestive system was designed for a diet that is full of raw plants and fruits, but many foods today are processed, refined, heated, and fragmented.

By eating foods that have lost their own natural enzymes, the pancreas and other organs that supply digestive enzymes are over-worked. This results in enzymatic function in other areas of the body to become compromised, which leads to disastrous health implications. Replenishing enzymes through diet and supplementation is an easy way to make up for the typical diet that is full of mostly dead foods.

The human digestive system is one of the most perfectly designed systems in the body, typically functioning without problems. This means that if we are eating the right foods in the right way, then we should not have to rely on antacids, H2 antagonists, PROTOn-pump inhibitors, and laxatives. Burping, belching, and bloating, no matter how often they occur, are actually not normal. It is ironic that the human body has a system that is far more impressive than any other machine built by humans, but we suffer from breakdowns all the time such as abdominal cramps after eating, inordinate amounts of gas, sluggish colons, and an overall lousy feeling after eating.

Statistics prove that we are not eating the right foods, and even if we were, many of us are not properly absorbing all of their nutrients because we consume huge amounts of sugar, drugs, caffeine, alcohol, and highly processed refined foods that prevent normal digestive processes. Being under constant stress and eating on the run, along with our unhealthy food choices, creates an environment inside our body that causes common cases of heartburn and indigestion, possibly leading to ulcers and colon disease.

Enzymes are protein molecules that are responsible for thousands of physiological reactions that take place in the human body. They initiate and control almost every biochemical process that occurs in the body, with nearly three thousand individual enzymes being identified to date. Enzymes help our body to digest food, repair tissue, and eliminate dangerous toxins. Digestive enzymes break down food particles, which allows them to pass through the intestinal wall and enter the bloodstream. The enzymes that are found in the blood transform nutrient particles into tissue that is found in muscles, nerves, organs, and glands.

Enzymes also contribute to the process that stores sugar in the liver and muscle tissue and preserves fatty tissue. Additionally, digestive enzymes are part of the chemical reaction that creates urea. Some enzymes even help to detoxify our blood and tissue by allowing our immune system to attack foreign material. Lastly, metabolic enzymes help create energy in our body on a cellular level by converting foot to energy, which then fuels nearly every mechanism in the body. Do you get enough enzymes on a daily basis?

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EDTA
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Date: January 03, 2009 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EDTA

Calcium is the most damaging mineral that is involved in the calcification of the blood vessel system. Ionic calcium, which is a floating form of calcium, is used by the body in daily functions like muscle contraction and relaxation, nerve impulse transmission, blood coagulation, and others. Calcium is a mineral that is capable of forming complexes with other components, such as proteins. These complexes can eventually lead to the formation of lesions, plaque, and the overall hardening of the blood vessels.

There are four different components that are found mainly in arterial walls which often combine with calcium. Elastin, a type of protein that makes up a good amount of the blood vessel wall, is the substance that allows the arterial wall to be elastic. During the process leading to atherosclerosis, elastin often forms complexes with ionic calcium, which results in a loss of elasticity.

Collagen, another type of protein that works with elastin to make up the bulk of arterial walls, forms complexes with ionic calcium, which leads to hardening of the blood vessel. MPCs, which are carbohydrates that contain a number of agents including amino acids, uronic acids, and chondroitin sulfate, are found within the arterial wall where they form complexics with ionic calcium to promote the formation of atherosclerosis. Beta lipoproteins and pre-beta lipoproteins transport a fatty acid and glycerol combination for storage in the liver, muscles, and other areas of the body.

Although beta and pre-beta lipoproteins form ionic calcium complexes and initiate the onset of arteriosclerosis, there are lipoproteins that do not form complexes with calcium, but interferes with the formation of ionic calcium complexes instead. It is clear that ionic calcium plays a huge role in the formation of arterial plaque and the actual hardening of arteries, due to the complexes it forms with components of the arterial wall. Because EDTA effectively ties up calcium complexes so that it can be eliminated through the urine, it is also clear why EDTA chelation therapy is a successful way to reduce the levels of atherosclerotic plaque and reverse the hardened condition that so often occurs in the artery walls.

EDTA chelation therapy was patented in Germany in 1930 and first used in medicine in 1941 to help with lead poisoning. It wasn’t patented in the United States until 1949, with several papers being published on its therapeutic effects following in the early 1950s. EDTA chelation therapy has been used in the U.S. to treat atherosclerosis since 1952, but was also used for lead poisoning and heavy metal toxicity before that. After its initial use for lead and heavy metal poising, it was noted that EDTA resulted in the reduction of severe pressure and pain in and around the chest, which led to the discovery of its abilities to treat atherosclerosis.

Since then, thousands of scientific articles have been written concerning the many aspects of EDTA chelation therapies as well as its safety, which has been proven by its use on thousands of patients in over three million intravenous treatments by over one thousand doctors in the last fifty years. Not one fatality has been documented when established PROTOcol has been followed, while the FDA approved the new drug application for EDTA without requiring any additional safety studies to determine its safe use. Have you tried oral EDTA?



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What is Hoodia?
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Date: April 08, 2008 08:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Hoodia?

1. What is Hoodia? Despite its similar appearance, the cactus-like hoodia is characterized as a succulent plant, which is a member of the milkweed family. Though there are about 20 species within the family, the active ingredient of hoodia is found only in the gordonii variety native to South Africa's vast Kalahari Desert

2. What assurances can be made that Source Naturals Hoodia Extract is authentic? Experts in succulent horticulture have helped ensure that the raw material Source Naturals uses to make Hoodia Extract is gathered from authentic Hoodia gordonii sources. From there, our supplier has an independent laboratory test the raw material, which is then issued with a certificate of analysis qualifying it as true Hoodia gordonii.

Once Source Naturals receives the certified Hoodia gordonii from our suppliers, we hold it to our own high standards and Total Quality Assurance. By putting it through stringent testing procedures in our quality control lab, we've carefully scrutinized the material. Before it ever reaches the hand of consumers, our high-quality hoodia is put through High Performance Thin Layer Chromatographic (HPTLC) analysis for authenticity, and microbiological screening for contamination, as well as other rigorous laboratory PROTOcols.

3. Could you explain the 20:1 ratio? 20:1 refers to the "wet to dry" ratio of the whole plant to concentrated powder. Hoodia gordonii contains an abundance of excess moisture that needs to be removed in order to make an effective, concentrated powder. The process by which that moisture is removed to yield the powder is an extraction. Basically, 20 pounds of whole plant is concentrated to one pound of the high-quality powder used to make our product.

What this means is, we've made a supplement with 20 times more functional hoodia than had we ground the plant up water and all. When you buy Source Naturals Hoodia Extract, you're getting all of the usable plant parts of the Hoodia gordonii times 20, because we've packed a greater amount of the quintessential hoodia ingredients into a powerful, concentrated powder.

4. Is a 20:1 concentrated extract more effective than 1:1 hoodia powder? We at Source Naturals certainly believe so. Unfortunately, the hoodia landscape has been unnecessarily clouded recently thanks to the misinformation circulating about concentrated extracts and so-called "100%" (1:1) hoodia powder. Most of the information is highly subjective, with no studies whatsoever to support claims that so-called "pure" powder is more efficacious than 20:1 concentrated extracts.

The common selling point for those propagating a 1:1 hoodia product is the notion that "more is better" - which, when you think about it, actually benefits a 20:1 concentrated extract. Because the logic behind using the 20:1 concentrated extract is that, in supplementation, it's not practical to ingest as much of the whole plant parts of hoodia as the San did to get the potential benefits of the plant. In using the concentrated 20:1 ratio, we're able to pack 20 times the amount of usable hoodia into our Hoodia Extract. How much more could you need?

5. Where was the hoodia in Hoodia Extract grown? On an approved farm in Northern Cape, South Africa.

6. Who is our supplier? Due to obvious business considerations, we don't want to specifically name our supplier and alert competitors to our source. However you can be assured that we receive our Hoodia gordonii from one of the industry's top suppliers, who was among the first and only importers of hoodia licensed to sell and import the plant into the United States.

7. I've heard there are sustainability issues with the plant. Is it endangered? It is true that the resources for Hoodia gordonii are limited due to early irresponsibility on those seeking to exploit the plant's benefits. However, Source Naturals Hoodia Extract has been produced with environmental sustainability in mind. We've made absolutely sure that only materials safely cultivated from the stems of seedlings grown on approved farms in South Africa have been used in making Hoodia Extract, not material indiscriminately picked in the wild.

8. How should it be used? Take one to two tablets or capsules with an 8 ounce glass of water about an hour before eating a meal.

9. Why does the label warning recommend consulting your health care professional before using this product if you are taking any prescription medication? This is a standard warning included on most Source Naturals product labels because generally it's a good idea to double check with your physician if you're taking prescription medication to make sure there aren't any special precautions you need to take while on the medication.

10. Does it contain caffeine? No. There is no caffeine in Hoodia gordonii, and Source Naturals Hoodia Extract does not contain any added caffeine.

11. Are there any side-effects? There are no known negative side-effects to taking hoodia products.

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Acai: The Super Antioxidant From Brazil
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Date: February 03, 2008 02:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acai: The Super Antioxidant From Brazil

Acai is an Amazonian palm tree, and possesses small purple fruits that the Amazonian natives of Brazil have used since time immemorial as food and as a remedy for certain health conditions that are now known to be associated with the activity on free radicals on body cells.

The active constituents of acai are powerful polyphenols and anthocyanin antioxidants that protect your body cells from oxidation by free radicals. In fact the plant has been referred to as ‘the super antioxidant from Brazil’ by many medical writers who have recognized its right to be termed as such. To understand that, you first have to understand what an antioxidant is and how it works. The chemical names of the active substances it contains will be meaningless without that background knowledge.

Oxidation occurs in your body even before you are born. What is does in general terms is to destroy your body cells, and the more it progresses the more your body is prone to cancers and cardiovascular diseases, and the more visible becomes the aging process. Chemically, oxidation is the loss of one or more electrons by an atom or molecule. Oxidation within your body is highly associated with what are known as free radicals. To explain these we have to consider the chemistry of electron pairs and free radicals, though this is not too technical so read on.

Normally electrons exist in pairs of opposite spin: in simple terms each pair makes up a single negative charge. Take hydrogen: its atomic structure contains one PROTOn and one electron. However, the hydrogen atom cannot exist by itself since the most stable configuration is that electrons exist in pairs with a net zero spin, so the hydrogen molecule consists of two hydrogen atoms with their own PROTOns sharing an electron pair. This is true of all covalently bonded molecules.

However, certain influences, such as pollution through tobacco smoke, pesticides, engine exhausts and the excess UV radiation of sunlight can cause a molecule to lose an electron. This creates what is known as a free radical: a molecule without an electrical charge but with an unpaired electron. Since the most stable configuration for it is to have a paired electron, the molecule will steal an electron from the most suitable candidate it finds.

In practise this will be a body cell, and the cell that loses the electron gets destroyed causing aging of the skin and many other undesirable effects, including cancers. This stealing of an electron is chemically referred to as oxidation. Antioxidants prevent this occurring to your body cells by being reactive themselves and preferentially mopping up these free electrons.

Polyphenols and anthocyanins are powerful antioxidants, and that is why the people of the Amazon rainforests have used acai not only as a food, but also for their health. It is only relatively recently that, as with many of the ancient health remedies, the scientific basis behind its use has been proved. The early Brazilian natives may not have understood biochemistry or what free radicals were, but they sure knew what was good for them.

As with many other foodstuffs containing powerful antioxidants, it is likely that it was the highly colored berries that first attracted them. That does not suggest that all brightly colored foods are good for you, but the brightly colored pigments and dyestuffs contained within them also tend to act as antioxidants due the same electron configuration that provides them with their color. Many of these chemicals are also use as food dyes, and have been used so since before their chemistry and antioxidant effects were known. The color comes from the same electron activity that makes them destroy free radicals. That is why most highly colored foods contain significant quantities of phytochemicals.

The deep purple color of the acai fruit led chemists to determine its content of polyphenols, such as anthocyanins, that are common in other highly colored foods such blueberries, peppers and aubergines. High concentrations of anthocyanins such as cyandin-3-glucoside and the rutinoside analogue were found, together with flavonoids such as orientin, deoxyhexose and scoparin. A total of twelve flavonoids were discovered that explains the highly antioxidant properties of the fruits. Laboratory and other tests have indicated that over 80% of the antioxidant effect of acai is due to polyphenols other than the anthocyanins. It is likely that these are the twelve flavonoids identified to date and any others that have still to be detected.

However, it is not only for its antioxidant properties that acai is such a healthy fruit, since it contains many other nutritional components. It contains fatty acids, including linoleic acid, an omega-6 fatty acid and also beta-sitosterol that are believed to reduce the level of LDL cholesterol in the blood. The fruit also contains a high level of amino acids, essential for the synthesis of proteins and DNA.

So what exactly does this mean for you in real terms? Antioxidants can do different things for different people, and the acai berry is said to have more than thirty times the antioxidant power of red wine. When you consider that many doctors believe one glass of red wine to provide sufficient antioxidant for the average person, you are getting a very high dose with acai berries, so what does it do for you?

Due its effect in destroying the free radicals caused by pollution, acai and similar powerful sources of antioxidants are becoming increasingly important to our diets. What was a sufficient antioxidant intake even twenty years ago is not longer sufficient. Acai can help to combat early aging by reducing the rate at which your body cells are destroyed by free radicals. It also reduces the risk of cardiovascular disease, and the associated high risk of strokes or heart attacks.

Acai juice itself has an unusually high fiber content, and helps maintain the health of your digestive system. An associated benefit of this is that you are less liable to contract colon cancer than if you did not consume it. Due to a reduction in the rate of destruction of body cells, including brain cells, elderly people benefit through maintenance of their brain function, and a lower likelihood of degenerating cognitive ability. It helps you to maintain concentration and memory, and can also reduce the risk of you getting cataracts.

Antioxidants are also known to help maintain the immune system, and act as anti-inflammatories, and it is believed that acai juice can help to reduce the symptoms of arthritis. If you use acai berries as part of a daily diet, you should receive the benefits that it provides, although a more measured dosage in the form of a supplement will enable you to control your intake of acai, and if one thing is certain it is that you will be far healthy with a regular dose of the superantioxidant from Brazil than without.



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Give Your Health A Boost With Silica Hydride A Powerful Antioxidant
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Date: January 18, 2008 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Give Your Health A Boost With Silica Hydride A Powerful Antioxidant

Hydride ions are strong PROTOn acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.

A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.

Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.

This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.

The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.

This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.

An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.

Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.

In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.

Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.

Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.

Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.

If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.



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Coconut Oil May Help Promote Healthy Thyroid and Digestive Function
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Date: November 01, 2007 09:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coconut Oil May Help Promote Healthy Thyroid and Digestive Function

Coconut is extracted from coconuts, the coconut palm often being called the tree of life and for good reason. However, its benefits were lost to America for many years due to the politics of the vegetable oil industry claiming that all saturated fats are bad. This is not based on scientific or medical fact, and coconut oil was recently rediscovered in the USA, and the health benefits enjoyed by the rest of the world are once again available to Americans.

Coconut palms grow in most tropical climates such as Southern California and Florida, the Philippines and the Caribbean. Refined coconuts oils are mass produced and much of the beneficial nutrients are lost by the refining process. Virgin coconut oil is by far the better form, though is a slower process. It is generally obtained by shredding and dry milling the meat, and then cold pressing to produce the milk. The milk is fermented for a day or so and the separated oil collected.

Such oils are analyzed to contain over 50% lauric acid and high levels of phenolic antioxidants. Much higher than from refined oils. It is said to be the healthiest oil on earth. So why did the American authorities legislate against its use? It is because of the bad press received by saturated fats and oils.

You can have saturated, monounsaturated and polyunsaturated fats. The majority of the fats and oils in our diet are composed of long chain fats and oils. The chain length refers to the length of the hydrocarbon chain, whether saturated or unsaturated. It is long chain saturated acids that are bad for your cardiovascular system, and that should be avoided. However, there are also short chain and medium chain fatty acids that are more easily metabolized by the body. Coconut oil consists predominantly of medium chain fatty acids that help to protect against heart disease and cholesterol rather than promote it.

The highest levels of medium chain fatty acids are found in coconut oils and palm kernel oils, and these are far more nutritious than the saturated long chain fatty acids found in animal fats and just about all vegetable fats. The main MCFA in coconut oil is lauric acid.

Lauric acid is generally regarded as being responsible for the vast majority of the health benefits of coconut oil. The only other source of this fatty acid other than coconut oil is in human breast milk. After absorption, lauric acid is metabolized into monolaurin that is the monoglyceride used by the human body to destroy viruses and microbes, and attack the fat coated viruses that cause such diseases as HIV. It destroys flu viruses, a number of dangerous bacteria and PROTOzoa such as giardia lamblia.

However, let’s have a look at some of the lesser known effects of coconut oil, such as its effects on the thyroid. Anything that blocks the efficient operation of the thyroid and secretion of the thyroid hormones can lead to excess estrogen in the body that can contribute to excessive blood cholesterol. There is a body of evidence that polyunsaturated fats and oils, such as soy, can have this effect is many people. When coconut oil is used instead, the medium chain fatty acids do not have the same effect, and those that are affected frequently find that their thyroid problem is cured and their blood cholesterol reduces.

This is not to infer that all hypothyroidism can be cured through the use of coconut oil, only those cases caused by consumption of excessive amounts of polyunsaturated fats. Although this is refuted by some medical practitioners that are against the use of supplements in general, it has been supported by medical evidence.

Coconut oil is also good for the digestion, and helps the cure of many digestive problems including Crohn’s Disease. It helps to build lipoproteins, fats and bile in the liver, the latter being essential for digestion. It helps to create a much healthier digestive tract that makes for generally better digestion and more efficient use of the foods you eat. Absorption of the nutrients is maximized and you feel altogether better in yourself when you take a small amount of coconut oil daily.

You can have sugar cravings for a number of reasons, and taking coconut oil can reduce these quickly and effectively, irrespective of their cause. The medium chain fatty acid breaks down and is rapidly metabolized to glucose thus providing a source of the energy your craving is telling you that you lack. It is very useful in reducing sugar cravings without you having to eat excess sugar that can create yeast problems.

If you replace the fats you are currently eating with coconut oil, it will not only act as an appetite suppressant but can also help you to lose weight. The fatty acids in coconut are absorbed immediately and converted to energy thus reducing your immediate need for food and hence your appetite. If you eat the saturated fat in coconut oil rather than the polyunsaturated fats in vegetable oils, then you can lose weight.

Many of the benefits of coconut oil are due to the speed with which the lauric acid is absorbed and metabolized in comparison to the long chain polyunsaturated fats. It is the chain length of the hydrocarbon tail that is important here rather than the number of double bonds in that chain that determines the degree of unsaturation.

Make sure that it is virgin coconut that you use since that is the most nutritious form. Do not be misled by labels claiming the contents to be extra virgin oil, since that is a term borrowed from the olive oil industry, and there is no such thing as extra virgin in relation to coconut oil. Never use refined coconut oil since that will just as bad for you as other saturated oils. Not even ‘Extra Virgin Refined Coconut Oil’ in the mistaken belief that such a label must indicate that the oil is extra good. It does not – it simply indicates that the supplier is a charlatan deliberately trying to mislead you into paying a premium price for a useless product.

Coconut oil may promote a healthy thyroid and digestive function, and all the medical tests indicate that it does. People that use it regularly swear by it and if you have a problem that virgin coconut oil might help, then one thing is sure: it will certainly do you no harm, and all indications are that it will do you a lot of good.



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Benefits - Supports joint function and tissue health*
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Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The PROTOcol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.



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Interview on symptoms of Fibromyalgia and one mans story
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Date: August 09, 2006 03:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Interview on symptoms of Fibromyalgia and one mans story

Interview with Todd Williams from Source Naturals

Todd: Michael, many of us know someone with fibromyalgia, but many of us don’t know what FM is. Can you help explain the disease?

Michael: Yes. Fibromyalgia (pronounced Fie-bro-my-AL-ja) is a complex chronic pain illness that challenges patients and health care professionals alike. It is estimated that fibromyalgia affects 8 – 10 million women, men, and children in the U.S. alone. Symptoms include: extreme fatigue, sleep abnormalities, cognitive problems, difficulty speaking clearly, memory loss, brain fog, and so on. There’s also irritable bowel syndrome, restless legs, migraine headaches, neurological symptoms, anxiety and environmental sensitivities. Ninety percent of those afflicted with fibromyalgia are women. Ten percent are men. What activates fibromyalgia within a person can be anything from a thyroid condition to an auto accident, or some type of trauma or emotional stress. There is often a compromised immune system, hormonal imbalance, and even a possible enzyme deficiency. Because the stomach and intestines are made up of muscles, fibromyalgia affects the entire digestive tract. The members in my fibromyalgia support group in Santa Monica all have stomach problems. One of the doctors believes that the fibromyalgia I have to battle with daily is a result of a thyroid problem. Thyroid problems run in my family and, not surprisingly, my brother, who lives on the other side of the country has fibromyalgia as well. We correspond and share with each other what does and doesn’t work. My ten-year career as a schoolteacher came to an end due to having fibromyalgia. I lost the energy I needed to work non-stop ten-hour days. I was forced by necessity to go into early retirement. As a result, I had to find a new manageable way to live. So I then went to Los Angeles to pursue a part time acting career. Now, regardless of whether a task is big or small, I just try to do my best, one day at a time.

Todd: Michael, how did you experience the onset of Fibromyalgia?

Michael: although I’ve really had fibromyalgia for fifteen years, I wasn’t actually diagnosed by my doctor until 1996. I was very energetic and athletic while growing up. During my twenties, I first went to University of Arizona in Tucson, and then to Oral Roberts University in Tulsa, Oklahoma, and later to Point Loma University in San Diego, where I received a Master’s Degree in education. I followed that by moving to Florida to teach and to spend some time with my family. During summer breaks from teaching, I would go down to Florida Keys and visit Miami for fun. I had plenty of energy up until I was 28-30 years old, when I noticed a drastic drop in my energy level. At that time, when I would exercise, it was very difficult for my muscles to recover after a workout, even if it was a light workout. By the time I was thirty, the muscles in my feet became unbearably tight. It became very difficult to stand or even walk very far. I had my feet X-rayed, and the reports would say that nothing was wrong. When I was thiry-five, I took some antibiotics to get rid of a cold and I ended up with severe reaction to the antibiotic, erythromycin. My stomach swelled up like a balloon and felt unbearably tight. This was my first experience with IBS (Irritable Bowel Syndrome). I could no longer digest my food. I developed severe food and chemical sensitivities. I could no longer digest vitamin B properly. I would be in excruciating pain for several hours after eating almost anything. I had to leave my teaching position and I ended up being mostly bedridden for two years due to exhaustion and the inability to digest food. During this time I went to twenty doctors. I had colonoscopys, endoscopies, barium x-rays and thyroid tests, but the results were always indicating a normal range. I knew that I was horribly sick but the doctors and the tests repeatedly said that nothing was wrong with me. nevertheless, the doctors did provide more prescription medicines, especially antibiotics. It’s strange that not one of these doctors mentioned or prescribed probiotics in any form for rebuilding the flora in my intestines that was destroyed by the long antibiotic regimen. Eventually I would end up spending a large sum of money and going to 40 more doctors, with each helping just a little. It was a relief when I was finally diagnosed with fibromyalgia, because it helped me narrow in on what was really going on. Which everything falling apart, it was a relief to know it wasn’t a rare foot disease, or a stomach parasite, or AIDS. I wanted to encourage men and women who are finally diagnosed with fibromyalgia to not see it as a death notice, but rather a step in recovery. In 2002, I tried something new. I went online and submitted my medical history to Dr. Teitelbaum’s Diagnosis Program, which you can find at www.vitality101.com. His incredible program spat out about 200 pages of very insightful information on what my body was deficient in. I began taking some of his recommended supplements and began to see some definite results. In spite of my poor track record with medical tests, he also recommended thyroid testing for fibromyalgia suffers, even though it is well known that thyroid tests are frequently wrong. Dr. Teitelbaum believes that many people who have fibromyalgia were actually having a thyroid problem, even though their thyroid tests come out in the normal range. I’ve had numerous thyroid tests over the years, and they’ve all been normal. I trekked back to my doctor and pleaded with him, even mentioning that there was a history of thyroid problems in my family. At first, he refused, simply because the tests said normal. I think doctors, fearing litigation, are reluctant to try a treatment path unsupported by test results. When you think about it, test ranges are really averages. What happens if your physiology falls outside the normal average? The tragic answer is: you can fall through the cracks! Finally, after much debate and arguing, I was able to get my doctor to provide a prescription for a small dosage of thyroid medicine. I began taking it immediately after two days I began to notice that the tight muscles in my stomach and legs began to loosen up. This seemed miraculous. Unfortunately, I also had some negative side effects from the medicine, so I stopped taking it. Nevertheless, I was amazed at how my body responded to such a small does of thyroid medicine. I think Dr. Teitelbaum is onto something. If you are fortunate enough to have an open minded doctor, perhaps that avenue is worth exploring. In Dr. Teitelbaum’s book, From Fatigue to Fantastic, he also advocates supplements for helping people with Fibromyalgia and chronic fatigue. I can verify that supplements have absolutely becomes part of my program and helped with restoring my systems to their natural balance. Some supplements that really helped me are: NADH, Glutathione, L-Carnitine, Acetyl L-Carnitine, revitalizing sleep formula, daily infusion powder and calcium D-Glucarate. Please feel free to check out the full list of supplements on my website. If you are fatigued, you should really read Dr. Teitelbaum’s book. To fibromyalgia sufferers, I highly recommend checking this list, visiting these doctors’ web pages, and trying their PROTOcols. Thanks to these doctors and various regimens, including supplements, my health is much, much better. Most people would have never guessed I went through such an ordeal. I still have to pace myself, and not push the limits. Staying healthy and maintaining my energy is a priority, so I’ve learned not to over-extend myself. I’ve learned to say no to some projects and activities and not feel guilty about it.

Todd: Wow! That’s a lot to go through. Facing such huge obstacles, how did you keep your ship facing forward?

Michael: Well, living and healing are spiritual events. I am fortunate to have a degree in theology and I have a strong daily spiritual practice, which has helped me to survive and thrive with complications of fibromyalgia. That’s not to say there haven’t been some very dark days, but faith in God and the support of my spiritual network, including my wonderful family and friends have made all the difference. After arriving at LA, I had moved into a little apartment across the street from Warner brothers. My roommate and I had decided to start a little bible study. We invited our neighbors and we prayed for many things including for my health to improve. One of our requests was for a door to open at Warner Brothers. Within a short time, our Bible Study group grew and our home couldn’t contain all the people. A year later, the doors opened for me at Warner Brothers, and I was working on the West Wing.

Todd: that’s Great! Can we tell the folks about your new show?

Michael: My web page has a new category called, “Nutrition Show”, which will provide all the details.

Todd: Thanks Mike! For more about Mike and fibromyalgia, please visit his website at: www.captainhastings.com



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The healing power of borage oil
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Date: June 19, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The healing power of borage oil

Borage oil, extracted from the seed of the blue, star shaped borage flower, is gaining much attention by alternative health practitioners and main stream medicine alike for its profound medicinal properties. Whereas the oil is getting all the redit, it is actually the oil’s active component, gamma linoleic acid (GLA), which has drawn the interest of researchers. The majority of the early studies done on GLA, dating back to the late 1940’s, were conducted with the oil of evening primrose. For rezones cited in the title, more bank for the buck, borage seed oil is now thought to be s superior source of GLA compared to evening primrose oil. Other plants forms and food concentrates that contain appreciable amounts of GLA include black currant seed oil and spirulina.

Why GLA Supplementation?

A body with healthy biochemistry has the ability to produce GLA from the most essential fat linoleic acid. Linoleic acid is found most abundantly in the omega 6 family of oils, including safflower, sunflower, and corn oil. While it has been estimated that a majority of Americans and Europeans consume far to many omega 6 fatty acids in proportion to the beneficial omega 3 fatty acids (by approximately 10:1). Most biochemists agree optimal ratio of omega 6 to omega 3 fatty acids should be approximately 1:1. Despite the obvious over consumption of omega 6 oils rich in linoleic acid, some individuals lack the ability to convert linoleic acid to the much needed GLA.

As is the example with many of our modern day nutrient deficiencies, the adulteration of our food supply by today’s processing methods has much to do with the faulty fat metabolism suffered by many. A prime example is the hydrogenation process utilized to convert liquid polyunsaturated oils into semi-solid, altered saturated fats for use as margarine and commercially processed foods. Hydrogenation is accomplished by subjecting the oils to temperatures in excess of 250 C, and bombarding them with hydrogen ions in the presence of the heavy metal nickel, which irreversibly changes the chemical structure of the fatty acid molecule from a healthful “cis” configuration to a dangerous “trans” configuration. When these products are eaten in excess they are known, in some cases, to block the enzymatic conversion of linoleic acid to GLA. In addition to the damaging effects of hydrogenation, certain essential fatty acid nutrient cofactor deficiencies may exist to further complicate the conversion. Vitamins pro-A, A, C, E, B-2, B-3, B-6, pantothenic acid, B-12 biotin and the minerals calcium, magnesium, potassium, sulfur and zinc are all involved in essential fatty acid (EFA) metabolism.

Particular interest should be given to those afflicted with diabetes, cystic fibrosis, asthma, alcoholism, multiple sclerosis. For a myriad of reasons, including cofactor deficiencies, these individuals lack the enzymatic ability to convert linoleic acid to GLA and must obtain a direct source of GLA for proper hormonal regulation. In addition, excessive consumption of animal fats containing acachidonic acid competes for the same metabolic pathways occupied by GLA, thus minimizing its biological action.

These potential negating effects can simply be diverted to consuming a food source or supplement containing GLA which bypasses any previously necessary enzymatic conversion and floods the metabolic pathways with beneficial GLA. Nutrient deficiency should also be addressed. Here lies the true power of GLA.

Prostaglandins, biochemical regulators

Whereas GLA is the power, the prostaglandins deliver the punch in this biological equation. Just as linoleic acid is normally converted to GLA, GLA is further converted into the prostaglandin E1 (PGE1). Many of the benefits derived from GLA supplementation are a result of the hormonal regulatory action of the prostaglandins. Just like the “parent” precursors they are made from, the hormone-like prostaglandins orchestrate a host of important biochemical activities. Their general regulatory effects include the control of arterial muscle tone, sodium excretion through the kidneys, blood platelet “Stickiness,” inflammatory response and the immune function, just to name a few. The list may be endless as scientists continue to discover the regulating effects of prostaglandins. One way in which GLA has shown to decrease the probability of allergic and inflammatory conditions is by competing with arachidomic acid, which when left unchecked may potentiate a hyperimmune response.

Healing Power

As a result of the powerful regulating effects derived from the conversion of GLA to healthful prostaglandins, borage oil and other GLA supplements have shown to be beneficial in the treatment and relief of many classic and modern day health problems. The disease of diabetes, cystic fibrosis, asthma, multiple sclerosis are thought to be helped by bringing about a balance in an otherwise faulty fatty acid metabolism. According to a study released in the journal diabetes care, supplementation with GLA has shown promise in the reversal of diabetic neuropathy (a condition where the nerves degenerate and symptoms of pain and numbness follow). The study concluded that all diabetics should be considered for dietary PROTOcol of GLA. Other conditions shown to benefit include high blood pressure, high cholesterol, skin conditions, arthritis, allergies, weight loss, improved behavior of hyperactive children and increased strength of hair and nails. Cited in the book, Super Nutrition For Menopause, written by the renowned nutritionist Ann Louise Gittleman, is one of the most popular applications of GLA supplementation in the relief of menstrual pain. Sufferers use a maintenance does up to the seventh day prior to menstruation, then double the dose for the duration of their menstruation. Dietary restrictions of meat, dairy and eggs during this time has also shown to compliment this regiment. Many would agree with Ms. Gittleman’s credo in allowing mother nature to cure our ails before relying on synthetic drugs which often come with side effects.

More Bang for the Buck

Now comes the challenge of acquiring a GLA supplement suited to meet your needs. With the help of the information below you may maximize your desired result while at the same time stretching your dollars. Lets take a look at the facts. We will limit out narrative to the tree most popular forms of GLA supplementation: 1) borage oil, 2) evening primrose oil and 3) black current seed oil. Potency is an important factor, as the higher the GLA content per gram, the more likelihood of greater biological activity. Borage oil contains 24% GLA, or 240mg per 1000 mg capsules. Black current seed oil contains 18%, or 180mg per 1000 mg capsule and evening primrose oil contains 10% GLA, or 100mg per 1000 mg capsule. While black currant seed may appear to run a close second to borage and have a slight edge on evening primrose, it contains a potent GLA inhibitor and should be considered last on the list. equally, if not more important than potency, is purity. Make it a practice not to purchase any oil product unless full disclosure of the method of extraction is printed on the label. If it is not, you may assume that the oil has been extracted in one of the following ways. Unfortunately, the popular use of the chemical hexane to extract oils is not required for disclosure. This method employs submerging cracked seed in a gasoline like substance (Hexane) and then slowly allowing it to evaporate off yielding 90% oil recovery. This is the most common method used to extract evening primrose oil because of the incredibly small, hard seed and low oil content. The second creative ploy is the claim that the oil has simply been extracted by a new high-tech method called supercritical fluid extraction (SCFE). This process “pregrinds” the seeds then subjects them to pressures of 6000 – 10000 psi in the presence of the gas CO-2. Under such intense pressure CO-2 gas becomes a liquid in which the seeds are submerged, ultimately yielding a 95% oil recovery. Look for oils that are labeled as “expeller pressed” without the damaging effects of light, heat and oxygen. The products should be contained in opaque (light resistant) bottles to protect them from the damaging effects of light. Optimally, you should find them in the refrigerated section of your local health food store. Due to the higher percentage of oil contained in the borage seed, as compared to evening primrose and black current, borage is typically priced well below the others making it the most potent and economical choice. All things considered an expeller pressed borage oil, contained in an opaque plastic bottle, may provide you the absolute best source of unadulterated GLA supplementation.

One company that provides such a product and always fulfills the quality requirements listed is Barlean’s Organic Oils. Their organic flax oil and borage oils are available at VitaNet.



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Lutein to fight age-related macular degeneration!
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Date: February 27, 2006 05:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lutein to fight age-related macular degeneration!

Lutein: The Antiordinary Antioxidant

Lutein belongs to a class of compounds known as carotenoids. Carotenoids in general are yellow, orange, or red pigments responsible for many of the colors of the foods we consume each day. To date, over 600 carotenoids have been identified in nature, but are only produced by plants, algae and bacteria leaving humans and animals to consume carotenoids in the diet. Forty to fifty carotenoids are consumed in the typical US diet, but only 14 have been detected in the blood, indicating a selective use of specific carotenoids by the body. Lutein is one of these carotenoids found in the blood and has been increasingly associated with eye health over the last decade.

Lutein’s role in eye health

In the human eye, lutein is concentrated in the center of the retina in an area known as the macula. Lutein is deposited in the macula through the lutein we consume in out diet or through supplements. This area is responsible for human central vision and is colored intensely yellow due to high concentrations of lutein. Lutein is thought to be beneficial for eye health by reducing damage in the eye in two ways: 1) by absorbing blue light (blue light is thought to increase free radical formation in the eye) and 2) by acting as an antioxidant, reducing damage in the eye caused by free radicals. Leading carotenoid researchers believe these functions may lead to a reduced risk of age-related macular degeneration (AMD) and cataracts.

Age-related macular degeneration

Macular degeneration is the leading cause of blindness in the USA in those over 65. twenty-five and thirty million people are afflicted worldwide and currently there are no effective treatments for the disease. The disease has two forms known as dry and wet AMD.

Ninety percent of AMD cases diagnosed are the dry form. In dry AMD, also referred to as early AMD, debris deposits under the center of the retina (known as the macula) interfering with its normal function. Parts of the macula atrophy, causing the central vision to slowly become dimmer or more blurry. Wet age-related macular degeneration, also known as late AMD, often develops in areas where dry AMD exists. Abnormal blood vessels grow and leak blood and fluid under the macula, causing scarring, which leads to rapid loss of central vision.

Dr. Joanna Seddon published one of the first studies demonstrating a link between lutein intake and AMD risk in 1994 (1). This epidemiological study compared the risk of developing AMD to nutrient intake and showed a significant reduction in risk for developing AMD as lutein intake reached 6mg per day (57% reduction in risk). Since the Seddon study, researchers have shown that increasing dietary lutein intake raises blood levels of lutein as well as levels of lutein in the eye (2). Bone et al. demonstrated that eyes with higher levels of lutein were less likely to be afflicted with AMD (3).

The latest clinical trial that investigated lutein’s role in AMD is known as the lutein antioxidant supplementation trial (L.A.S.T) (4). This study evaluated the effects of lutein supplementation for one year in 90 veterans diagnosed with dry AMD. Supplementation with lutein in these subjects significantly increased the concentration of lutein in the macula. Improvements in visual function were also detected with lutein supplementation. Glare recovery, visual acuity, and contrast sensitivity were all improved. This study continues to build on clinical evidence that the dry form of AMD may be responsive to changes in nutrition.

Cataracts

A cataract is a natural clouding of the lens, the area of the eye responsible for focusing light and producing clear, sharp images. For most people, cataracts are a natural result of aging. Currently in the US, cataracts are the second leading cause of blindness in the elderly behind AMD.

Lutein is the major carotenoid that has been identified in the human lens asn is thought to provide similar benefits to the leans that are seen in the retina. Two large epidemiological studies consisting of >70,000 women (age 45-71) and >30,000 men (age 45-75) compared the risk of cataract extraction to nutrient intake (5,6). Similar to AMD, a significant reduction in risk of cataract extraction was associated with lutein intakes of 6mg per day (20% reduction in risk). Besides cataract extraction, higher levels of lutein consumption have been associated with a decreased risk of cataract development and improvements in visual acuity and glare sensitivity in people with age-related cataracts.

Lutein consumption

The richest source of free lutein in the typical US diet are dark green leafy vegetables, with the highest concentration found in kale followed by spinach.

The average daily lutein intake is low, average between 1-2 mg/day. Currently there is no recommendations of the dietary guidelines for Americans 2005 (9 servings of fruits and vegetables every day) you would consume between 4 and 8 mg of lutein a day (7). Epidemiological evidence, animal models, and clinical data have indicated levels of 6-10 mg a day may be necessary to realize the health benefits associated with lutein consumption. By continuing to increase our intake of lutein, we begin to ensure the optimal health of our eyes.

References:

Seddon et al. (1994) dietary carotenoids, vitamin a, c, and e, and advanced age-related macular degeneration. Eye disease case-control study group. JAMA. 272: 1413-20.

Bone et al. (2000) Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Exp. Eye Res. 71: 239-45.

Bone et al. (2001) Macular pigment in donor eyes with and without AMD: a case-control study. Invest. Ophthalmal. Vis Sci. 42: 235-40.

Richer et al. (2004) Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-relaged macular degeneration: the veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 75: 216-30.

Brown et al. (1999) A prospective study of carotenoid intake and risk of cataract extraction in the US men. Am. J. Clin. Nutr. 70: 517-24.

Chasen-Taber et al. (1999) A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am. J. Clin. Nutr. 70: 509-16

HHS/USDA. Dietary Guidelines for Americans 2005. //www.healthierus.Gov/dietaryguidelines/CDC. National health and nutrition examination survey data 2001-2002. //www.cdc.gov/nchs/about/major/nhanes/nhanes01-02.html

Brandon lewis, Ph.D. is the applied research and Technical services manager at kemin health, L.C. in des moines, iowa. His responsibilities include the initiation and management of laboratory projects pertaining to the inclusion and analysis of kemin ingredients in vitamins and dietary supplements, as well as developing new applications and PROTOtypes that include kemin ingredients. Prior to joining kemin, Brandon was enrolled at the university of Florida where he received his Ph.D. in Nutritional Science from the department of Food Science and Human Nutrition.



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Molecularly Distilled Omega-3 fish Oil Fact Sheet
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Date: January 12, 2006 03:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Molecularly Distilled Omega-3 fish Oil Fact Sheet

Molecularly Distilled Omega-3 fish Oil Fact Sheet

Neil E. Levin, CCN, DANLA 10/26/04

LIKELY USERS: Everyone consuming fast foods or diets high in vegetable oils; People with family history of heart disease or diabetes; People with inflammatory conditions

KEY INGREDIENT(S): Molecularly distilled fish oil concentrate

MAIN PRODUCT FEATURES:
  • Cholesterol free
  • Natural lemon flavor
  • This oil is easier for many people to tolerate than other fish oils
  • Antioxidant blend of Rosemary Extract, Ascorbyl Palmitate and Natural Tocopherols
  • Natural triglyceride form (unlike some other brands using the ester form)
  • Manufactured and distilled in a pharmaceutical facility in Norway according to pharmaceutical PROTOcols
  • Molecularly distilled and screened for the absence of potentially harmful levels of contaminants (i.e. mercury, heavy metals, PCB's, dioxins, etc.)
  • Derived from open sea catches of sardines and anchovies
  • Also available in unflavored enteric-coated capsules
OTHER IMPORTANT ISSUES:
 
  • Molecular distillation removes impurities such as pesticides (PCBs, PCDFs, PCDDs, Dioxin) and heavy metals (mercury, lead)
  • Exceeds contaminant safety standards per CRN monograph and California state law
  • No trans-fats
  • Consumption of Omega-3 fatty acids may reduce the risk of coronary heart disease. (FDA evaluated the data and determined that, although there is scientific evidence supporting the claim, the evidence is not conclusive.)
  • Helps control triglycerides and prevent excessive clotting>
  • Promotes anti-inflammatory prostaglandins that also encourage dilation of blood vessels
  • Essential for brain, nerves, cell membranes and blood sugar metabolism
  • Aids in maintaining normal heart rhythm

    AMOUNT TO USE: One teaspoon a day provides 740 mg. of EPA and 475 mg. of DHA. Use one or more teaspoons per day.

    SYNERGISTS: Other supplements used as cardiotonics include Vitamin E, CoQ10, magnesium, antioxidants, garlic, ginger, cayenne pepper, L-carnitine and hawthorn leaf and flower extract.

    CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. But no cautions have been noted to date for pregnant or nursing women using fish oils, which are often recommended for pregnant and nursing women.

    Disclaimer:  These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.




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    Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
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    Date: December 07, 2005 12:16 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet

    Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

    LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue

    KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients

    MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.

    Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.

    Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.

    OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.

    AMOUNT TO USE: Three or more capsules a day, preferably with meals.

    COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.

    AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)

    CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

    REFERENCES:

    1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
    2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723–7 [in Hungarian].
    3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind PROTOcol.) Orv Hetil 1990:131:863–6 [in Hungarian].
    4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871–9.
    5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179–80.
    6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39–44.
    7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson’s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189–202.
    8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179–80.
    9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
    10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153–5.
    11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35–44.
    12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
    13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
    14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719. 15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
    16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
    17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67. 18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
    19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
    20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
    21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
    22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
    23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
    24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
    25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
    27. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
    28. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
    29. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.



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    Vitanet ®

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    Source Naturals - Our Commitment to Your Well-Being
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    Date: August 20, 2005 11:41 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Source Naturals - Our Commitment to Your Well-Being

    Source Naturals 49% OFF

    Manufacturing nutritional supplements is a profound responsibility. We are constantly aware that the products we make are incorporated into your cells and tissues—they become the very substance of your being.

    Our Commitment to Your Well-Being

    As developers of a leading line of dietary supplements, we at Source Naturals know we have a unique responsibility.

    When you take our supplements into your body, you entrust us with something precious and irreplaceable—your physical and mental well-being. You expect us to honor that trust by producing the highest quality supplements, based on advanced research, in formulations that can significantly impact your life. You expect Total Quality Assurance (TQA™).

    A Culture of Quality Our Quality Control Department employs rigorous testing Our Commitment toYour Well-Being procedures that assure every product we produce is of the highest quality. We have set in place intricate PROTOcols of checks and balances. But our commitment to quality does not begin or end at the laboratory door. From purchasing to warehousing, from the first stage of blending to the finishing touches in packaging, we continually strive to imbue quality at all points in our systems.

    Clear PROTOcols, policies and procedures establish the framework, but TQA at Source Naturals is a living system of dedicated people. TQA is our organizing principle. The whole company is structured around quality circle teams. They are fast and creative, enabling us to quickly take nutritional quality to the next level of performance. There is no entrenched bureaucracy, intent on maintaining the status quo. Instead, staff members participate in teams focused on the continual improvement of our products. In our everevolving quality circles, team members are encouraged to brainstorm and think “outside the box,” to discover innovative ways to raise product quality.

    In these quality circle teams, one guiding principle is always focused on and reinforced—creating products that enhance the health and well-being of our customers.

    Quality and Formulation

    And because you take our products to address critical health concerns, the heart of TQA at Source Naturals is our formulation method. We understand the need to go deep to the underlying causes of health imbalances. Whether developing groundbreaking nutrients or comprehensive formulas, we are dedicated to accessing and addressing those root causes. For a step-by-step tour of TQA at Source Naturals, please read on.

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    Curcumin - Turmeric Extract
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    Date: August 19, 2005 12:47 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Curcumin - Turmeric Extract

    Curcumin

    Turmeric- History and Traditional Usage

    Native to Southeast Asia, Curcuma longa is a tall
    tropical shrub with large oblong leaves and pale yellow flowers.
    The genus “Curcuma” belongs to the Zingiberaceae family, which
    includes ginger.1 The plant possesses a large root structure
    with fleshy, bulbous underground parts called “rhizomes.” These
    rhizomes, known as turmeric root, are harvested at maturity,
    dried and cured for commercial use. Chemical analysis shows that
    dried turmeric contains essential and volatile oils, with a
    curcuminoid content of 2.5 to 5.0 %.2

    In addition to its
    popularity as a spice, turmeric is used as a dye for cloth and
    coloring agent in foods and cosmetics, thanks to its rich yellow
    color. Turmeric also serves as a preservative, probably owing to
    the antioxidant and antimicrobial properties of curcumin.
    Extracts of Curcuma longa have demonstrated in vitro
    antibacterial and anti-fungal effects.3

    Turmeric is named in
    ancient Ayurvedic and Chinese herbal texts as a traditional folk
    remedy. Historically, turmeric was used externally for wounds,
    and sprains, and internally for digestive complaints,
    rheumatism, liver disorders, coughs and colds.4
    Benefits

    Protects cells and tissues by fighting free radicals.*

    Supports joint function*

    The numerous beneficial
    effects attributed to turmeric stem in large measure from the
    antioxidant properties of curcumin. Antioxidants neutralize free
    radicals, which are highly unstable molecules that can damage
    cellular structures through abnormal oxidative reactions.
    Curcumin is a potent “scavenger” of the superoxide radical, a
    free radical that initiates potentially harmful oxidative
    processes such as lipid peroxidation.5 Through this activity,
    curcumin has been shown to protect skin cells from the injurious
    effect of nitroblue tetrazolium, a toxin that generates
    superoxide radicals. Curcumin also increases survival of cells
    exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
    which stimulates superoxide and hydrogen peroxide production.
    Curcumin itself is not toxic to cells, even at high
    concentrations. Pure curcumin was shown to be less protective
    than a mixture of curcuminoids, indicating a possible synergism
    among curcuminoids.6 Because free radicals are involved in aging
    and exert harmful effects on skin, these results suggest
    curcumin may help slow skin aging.

    Curcumin demonstrates
    several other in vitro effects linked to free radical
    scavenging. Curcumin scavenges nitric oxide, a compound
    associated with the body’s inflammatory response.7 Pure curcumin
    and turmeric extracts protect red blood cells from lipid
    peroxidation induced by hydrogen peroxide.8 Curcumin has been
    shown to protect DNA from oxidative damage, inhibit binding of
    toxic metabolites to DNA, and reduce DNA mutations in the Ames’
    test.9 Although additional studies suggest an anticarcinogenic
    effect of curcumin, through protection of DNA,10 one in vitro
    study found that curcumin induced DNA damage in human gastric
    mucosal cells.11 It is speculated that curcumin may act as a
    pro-oxidant in the presence of transition metal ions such as
    copper and iron. (This is true for other antioxidants, including
    vitamin C.) Curcumin also demonstrates in vitro inhibition of
    COX-I and COX-II enzymes, which are involved in the inflammatory
    reaction.12 Together these results strongly suggest that
    curcumin is a potent bioprotectant with a potentially wide range
    of therapeutic applications.

    Animal studies- In vivo protective effects

    Through its free radical scavenging
    properties, curcumin has shown bioprotective effects in animals.
    In one study, rats were treated with isoproterenol, a chemical
    that causes cardiac hypertrophy (enlargement of the heart) due
    to abnormal collagen metabolism. Co-treatment with curcumin
    reversed the degradation of collagen and cardiac hypertrophy
    induced by isoproterenol.13 Curcumin protects mice from
    detrimental effects of radiation, by stabilizing the glyoxalase
    system, a biological system that regulates cell division.14
    Curcumin protects livers of rats from the damaging effects of
    carbon tetrachloride (CCl4), a potent hepatoxin that injures the
    liver via its free radical metabolite, CCl3.15,16 Curcumin
    protected rats from alcohol-induced brain damage, in a study in
    which oral administration of curcumin reversed lipid
    peroxidation, reduced levels of free-radical metabolites and
    increased levels of glutathione, a major physiologic
    antioxidant.17 Curcuma longa extracts have shown
    anti-inflammatory effects in rats.18

    Human Trials

    Curcumin exhibits free-radical scavenging ability when
    administered to humans. In an open trial (uncontrolled), 18
    healthy individuals ranging in age from 27 to 67 years consumed
    a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
    for 45 days. Before and after blood tests showed a statistically
    significant decrease in lipid peroxides.19 Preliminary trials
    have tested the anti-inflammatory action of curcumin, with
    results that verify the traditional use of turmeric as an
    anti-rheumatic herb. In a short-term double-blind, cross-over,
    comparative study, 18 people received curcumin (1200 mg daily)
    or phenylbutazone for two week periods. Both curcumin and
    phenylbutazone produced measurable improvements in joint
    flexibility and walking time. The subjects reported results only
    with phenylbutazone, which may be explained by the short
    duration of the trial.20 In a small placebo-controlled trial
    comparing curcumin to phenylbutazone, 45 patients with
    post-operative inflammation received curcumin, phenylbutazone or
    placebo. The anti-inflammatory effects of curcumin and
    phenylbutazone were comparable and superior to placebo.21
    Curcumin has not been found to produce an analgesic (pain
    relieving) effect.

    Bioperine-Nature’s Absorption Enhancer
    Boosts Curcumin Absorption*

    Traditional Ayurvedic herbal
    formulas often include black pepper and long pepper as
    synergistic herbs. The active ingredient in both black pepper
    and long pepper is the alkaloid, piperine. Experiments carried
    out to evaluate the scientific basis for the use of peppers have
    shown that piperine significantly enhances bioavailability when
    consumed with other substances.22 Several double-blind clinical
    studies have confirmed that Bioperine® increases absorption of
    nutrients.23

    Curcumin is poorly absorbed in the intestinal
    tract, limiting its therapeutic effectiveness. Oral doses are
    largely excreted in feces, and only trace amounts appear in the
    blood. Concomitant administration of 20 mg of piperine with 2
    grams of curcumin increases the bioavailability of curcumin by
    2000%.24

    Scientific References


    1. Majeed, M., Badmaev,
    V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
    Piscataway, NJ: NutriScience Publishers.
    2. Srimal, R.C.
    Turmeric: a brief review of its medicinal properties.
    Fitoterapia 1997;68(6):483-93.
    3. Ammon, H.P.T., Wahl, M.A.
    Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
    4.
    Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
    The PROTOcol Journal of Botanical Medicine, Autumn
    1995:43-46.
    5. Rao, N.S., Rao, M.N.A. Free radical scavenging
    activity of curcuminoids. Arzneim.-Forsch./Drug Res.
    1996;46(2):169-171.
    6. Bonté. F. et al. Protective effect of
    curcuminoids on epidermal skin cells under free oxygen radical
    stress. Planta Medica 1997;63:265-66.
    7. Rao, S., Rao, M.N.A.
    Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol.
    1997;49:105-7.
    8. Lalitha, S., Selvam, R. Prevention of
    H2Os-induced red blood cell lipid peroxidation by aqueous
    extracted turmeric. Asia Pacific J Clin Nutr
    1999;8(2):113-14.
    9. Deshpande, S.S., Maru, G.B. Effects of
    curcumin on the formation of benzo[a]pyrene derived DNA adducts
    in vitro. Cancer Letters 1995;96:71-80.
    10. Subramanian, M., et
    al. Diminution of singlet oxygen-induced DNA damage by curcumin
    and related antioxidants. Mutation Research
    1994;311:249-55.
    11. Blasiak, J., Trzeciak, A., Kowalik, J.
    Curcumin damages DNA in human gastric mucosa cells and
    lymphocytes. Journal of Environmental Pathology, Toxicology and
    Oncology 1999;18(4):271-76.
    12. Ramsewak, R.S., DeWitt, D.L.,
    Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
    activities of Curcumins I-III from Curcuma longa. Phytomedicine
    2000;7(4):303-308.
    13. Nirmala, C. Anand, S., Puvanakrishnan,
    R. Curcumin treatment modulates collagen metabolism in
    isoproterenol induced myocardial necrosis in rats. Molecular and
    Cellular Biochemistry 1999;197:31-37.
    14. Choudhary, D.,
    Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
    system by curcumin. Journal of Ethnopharmacology
    1999;64:1-7.
    15. Park, E-J. et al. Protective effect of
    curcumin in rat liver injury induced by carbon tetrachloride. J
    Pharm. Pharmacol. 2000;52:437-40.
    16. Deshpande, U.R. et al.
    Protective effect of turmeric (Curcuma longa L.) extract on
    carbon tetrachloride-induced liver damage in rats. Indian
    Journal of Experimental Biology 1998;36:573-77.
    17.
    Rajakrishnan, V. et al. Neuroprotective role of curcumin from
    Curcuma longa on ethanol-induced brain damage. Phytotherapy
    Research 1999;13:571-74.
    18. Arora, R.B. Basu, N., Kapoor, V.,
    Jain, A.P. Anti-inflammatory studies on Curcuma longa
    (Turmeric). Indian J Med Res 1971;59(8):1289-95.
    19.
    Ramirez-Bosca, A. et al. Antioxidant curcuma extracts decrease
    the blood peroxide levels of human subjects. Age
    1995;18:167-69.
    20. Deodhar, S.D., Sethi, R. Srimal. R.C.
    Preliminary study on antirheumatic activity of curcumin
    (diferoyl methane). Indian J Med Res 1980;71:632-34.
    21.
    Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
    anti-inflammatory property of curcumin (diferoyl methane) in
    patients with postoperative inflammation. International Journal
    of Clinical Pharmacology, Therapy and Toxicolgy
    1986;24(12):651-54.
    22. Atal, C., Zutshi, U., Rao, P.
    Scientific evidence on the role of Ayurvedic herbals on
    bioavailability of drugs. Journal of Ethnopharmacology
    1981;4:229-232.
    23. Bioperine®–Nature's Bioavailability
    Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
    Corporation, Piscataway, N.J.
    24. Shoba, G., et al. Influence
    of piperine on the pharmacokinetics of curcumin in animals and
    human volunteers. Planta Medica 1998;64(4):353-6.

    © 2002
    Doctor's Best, Inc. Revised 8/13/02

    *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.



    --
    Vitanet ®

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    ST. JOHN’S WORT AND AIDS/HIV
    TopPreviousNext

    Date: July 15, 2005 09:28 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: ST. JOHN’S WORT AND AIDS/HIV

    ST. JOHN’S WORT AND AIDS/HIV

    In 1991, some of the first work focusing on St. John’s wort’s effects on AIDS and the HIV virus began. Science magazine reported on the first study using the isolated hypericin, a key compound in Hypericum.16 Fred Valentine and Howard Hochster, researchers at New York University Medical Center, began one of the first studies looking at how hypericin can help uninfected T-cells from being infected with the AIDS virus in a cell culture. Their focus was on hypericin because it is a virucidal agent, meaning it can precisely target new virus particles and prevent them from infecting other cells.

    The only two drugs at that time approved for treating HIV infection—AZT and ddI—work by interfering with the key viral enzyme, reverse transcriptase. Since hypericin works more effectively than many drugs in regards to the reverse transcriptase phase, and since many animal tests have shown that it has low toxicity at therapeutic doses, researchers (including Valentine and Hochster) began these studies largely hoping that not only would hypericin work on its own, but that it would have a sort of synergistic effect when used with either AZT or ddI. 17

    Additional studies are pointing to St. John’s wort, and more so, hypericin, as having great potential in treating HIV. Acosta and Fletcher recently detailed the processes in which the human immunodeficiency virus works to infect human cells, and point out that hypericin is at least somewhat effective in inhibiting the four main phases of virus “growth”— binding and entry, reverse transcriptase, transcription and translation, and viral maturation and budding (the researchers note that hypericin is especially effective in binding and entry, the first phase.) This denotes that hypericin could eventually have special importance in completely stifling the development of the growth of any virus, and most importantly, that of the HIV virus.18

    Another study assessing the use and attitudes of HIV sufferers concerning the use of more alternative treatments for the virus as opposed to clinical drug therapies showed both an extensive use of unconventional therapies and a very favorable response to using the alternative treatments, which, of course, St. John’s wort was among. “Participants at all sites expressed positive views upon increasing unconventional remedies.”19 The fact is that the world of synthetic medicines has been basically ineffective in not only treating and relieving the symptoms of AIDS, but also in finding a cure for the dreaded disease. Sufferers are giving alternative therapies a try, and the results are very promising.

    A 1995 review appearing in Photochemisty-Photobiology treated the photodynamic properties of both hypericin and the structurally related hypocrellins for their anticancer and antiviral properties (especially the anti-human immunodeficiency virus). This article states that the promising anticancer and antiviral results obtained both in vitro and in vivo [in differing studies] have led to intensive investigation into their photo-physical and photochemical processes, especially kinetic studies of their intramolecular PROTOn transfer . . . The biomedical advances of hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericin.20

    Another study published in the September 1994 issue of Photochemistry-Photobiology gave hypericin the upper hand over the hypocrellins in treating HIV. Just one more vote in favor of promoting the use of St. John’s wort, and more specifically, hypericin, for use in treating HIV and in overall clinical medicine.

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    Bio-Chelation
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    Date: June 29, 2005 05:38 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Bio-Chelation

    Bio-Chelation* By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt In The Beginning The Bio-Chelated¨ process describes a proprietary cold extraction technique developed by Mr. Frank D'Amelio Sr., founder and owner of Nature's Answer¨, and well- respected author*. Long before Nature's Answer¨ was formed (early 1970's), Mr. D'Amelio was immersed in the study of botanical medicine, researching the various herbal texts including the national USP/N.F. (United States Pharmacopeia/National Formularies) dating back to the mid -1800's. (The USP/N.F. is a reference source that provides manufacturing standards and extraction techniques used to make herbal formulas; these standards were considered official prior to 1938.) This authoritative formulary discussed the use of plant parts such as leaf, stem, bark, flowers and roots. It recommended certain solvents known as "menstruums", in which plant parts were soaked in order to extract their active constituents. High heat was also often utilized to concentrate the extract. Mr. D'Amelio noticed that high amounts of solvents, usually alcohol, were often recommended, and that sediment would fall to the bottom (precipitate) in certain solutions. He began to investigate how he could offer the consumer potent herbal products made with very low heat, with minimum precipitation, and without a lot of alcohol!

    A Clue From Nature In working towards the goal of attaining a final botanical extract product with little alcohol, Mr. D'Amelio turned to Nature for the apparent answer. He realized that plants were composed of 80-85% water as well as some alcohols, fats, etc. If plants were able to keep the active constituents in solution and use them as needed mainly through water, not alcohol or other solvents, why couldn't he? Thus, he began a long, in-depth series of experiments with many different plants. Through rigorous research PROTOcols and scientific testing, he discovered that the active constituents of some plants could be extracted using lower alcohol amounts with water and other natural solvents such as organic apple cider vinegar or vegetable glycerine. At other times, however, higher alcohol was necessary, such as when he was extracting volatile oils like menthol from peppermint. The experimentation process continued, with Mr. D'Amelio documenting the optimum menstruum combinations required for each plant to yield the maximum beneficial components. (Note that there are differences in alcohol. The alcohol consumed in wine and beer is derived through a natural fermentation process with no processing other than filtration. When distilled alcohol is added to an extraction, which some herbal manufacturers use, it effects the body in a more detrimental way; thus the development of the Bio-Chelation¨ process, which uses only organic alcohol).

    The Bio-Chelated¨ Method Is Developed As Mr. D'Amelio continued his experimentation with various plants and menstruums, his extraction processes became more refined, and eventually led to the development of the Bio-Chelated¨ method. The Bio-Chelated¨ method incorporates soaking for a period of time, using different menstruum ratios for different plants to optimize their therapeutic values. Furthermore, this procedure offers additional significant advantages when compared with other types of extraction processes commonly employed by competitors in the herbal industry.

    Bio-Chelation includes the use of "cold extraction", where the plant parts are extracted without being exposed to excessive amounts of heat. Cold extraction helps the herb maintain vital minerals and other trace elements in solution, thus enabling the herb to keep its Holistic Balanceª intact. (Holistic Balanceª means that extracts retain as many of the natural constituents of the original plant as possible.) In addition, the Bio-Chelated¨ process incorporates the use of an exclusive technique that removes much of the alcohol used during the menstruum soaking (maceration) phase, replacing it with vegetable glycerin instead. The resulting yield is an herbal extract that is either alcohol-free, or has a low alcohol content. (Both alcohol-free and low alcohol products from Nature's Answer feature vegetable glycerin only. Glycerin is used because it helps bind certain plant constituents, is natural to the body, is easily absorbed by the cells and has little insulin response. Only vegetable glycerin has been used since 1972. In addition, all alcohol used in Nature's Answer's low alcohol formulas is certified organic.)

    The Bio-Chelated¨ method was the first extraction process to yield a 12-14% alcohol extract in the herbal industry!

    Nature's Answer Stands The Test of Time Over the last quarter of a century (since 1972), the Bio-Chelated¨ cold extraction process has been painstakingly tested and proven to stand the test of time. Incorporating Mr. D'Amelio's proprietary cold extraction process in today's manufacturing procedures continues to yield a measurably superior product. One such example is Saw Palmetto from Nature's Answer¨, a product that is produced utilizing our Bio-Chelated¨ method versus the more expensive CO2 method. Our Bio-Chelated¨, cold extraction process yields a product that not only contains the same amounts of active constituents as the more expensive CO2 extracted product, but features a higher percentage of polyphenols, the compounds responsible for the herb's antioxidant properties. The end result is a Saw Palmetto extract that maintains its holistic balance! (Note that most prior successful studies done on Saw Palmetto utilized grain alcohol extracts which contained naturally occurring polyphenols; the CO2 extracted products do not contain polyphenols!) Although larger quantities of herbal products are now being produced as compared to the earlier experimental batches made by Frank D'Amelio, his founding corporate philosophy remains intact - combine the greatest care with the highest quality of raw material to create the ultimate herbal extract that works. After all, that's what it's all about, isn't it? Bio-Chelated¨..Another reason to count on Nature's Answer Without Question! Manufacturing Highlights:

    State-of-The-Art Laboratory Manufacturing Equipment HPLC, UV, IR, GC/MS, LC/MS, TOC and Densitometer 316 Pharmaceutical Grade Stainless Steel or Glass Lined Extraction Vessels (instead of the inexpensive, more commonly used plastic or polyethylene extraction vessels; these vessels are porous and may contain microorganisms, residual plasticizers that are difficult to clean and could cross contaminate different batches of herbs) FDA Registered & Pharmaceutically Licensed cGMP and SOP Compliant Manufactured in the U.S.A. *Botanicals - A Phytocosmetic Desk Reference (1999), Botanical & Herbal Folklore (1974), The Botanical Practitioner (1978) Bio-Chelated¨ is a registered trademark of Bio-Botanica Inc.¨ Holistic Balanceª is a trademark of Bio-Botanica Inc.¨

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    Alcohol-Free Herbal Extracts
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    Date: June 29, 2005 05:20 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Alcohol-Free Herbal Extracts

    Alcohol-Free Herbal Extracts By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt

    Alcohol: The First Menstruum

    Liquid extracts are a time tested, effective delivery system for medicinal herbs. When choosing liquid extracts, read the label. You will usually see that they contain quite a bit of alcohol. Alcohol is used as a menstruum, or solvent that frees all of the constituents from the fiber and cellulose of the plant, so that the specific medicinal constituents we want become more bio-available to the body. Alcohol has traditionally been used as the menstruum of choice because it is one of the most effective solvents (materials used to pull out the constituents of the herb) that is both reasonably priced and not too toxic on the body. Most of the herbal extracts on the market today have an alcohol content between 30 to 70%.

    Bio-Chelation: A Revolutionary Concept

    In the 1970’s Mr. Frank D’Amelio Sr., CEO and founder of Nature’s Answer®, noticed that the United States Pharmacopeia (the text that was used as a formulary for herbal processing), recommended using high amounts of alcohol to extract active constituents from the plant. He began to wonder how he could offer consumers potent herbal products without a lot of alcohol. One clue from Nature that became apparent to him was the fact that plants themselves were composed of 80-85% water. Since plants were able to keep their active constituents in solution and use them as needed through the use of water, not alcohol or other solvents, why couldn’t he? He began a long, in depth series of experiments with many different plants. Through rigorous research PROTOcols and scientific testing, he discovered that the active constituents of some plants could be extracted using lower alcohol amounts along with water and other natural solvents, such as organic apple cider vinegar. (Conversely, higher alcohol was necessary at times when volatile oils were being extracted such as menthol from peppermint.) The experimentation continued, as Mr. D’Amelio recorded the optimum menstruum combinations required for each plant to yield the maximum medicinal components. He further refined the process, eventually developing the proprietary Bio-Chelation® cold extraction method.

    The Bio-Chelation technique describes an exclusive process that removes much of the alcohol used during the menstruum, or soaking phase, and replaces it with vegetable glycerin, yielding extracts that are either alcohol-free, or have a low alcohol content. In addition, the alcohol used in any Nature’s Answer herbal extract product has the further distinction of being ‘organic’.

    The Bio-Chelation method yielded the first 12-14% alcohol extract in the herbal industry!

    The Alcohol-Free Advantage

    There are many reasons why people may not want to use herbs with high alcohol content. Some people dislike the strong taste of alcohol. Alcohol can stress a weakened or under-functioning liver in sensitive individuals, such as those suffering from allergies, environmental sensitivities, systemic candida, and/or a host of other health concerns. Furthermore, people in recovery from alcoholism cannot use alcohol. Finally, alcohol is not appropriate for young children.

    Nature’s Answer's alcohol-free extract formulas replace alcohol with natural vegetable glycerin because glycerin helps to bind certain plant constituents and is easily absorbed by the cells. Glycerin occurs naturally throughout the body. It also makes up a portion of the cellular membranes. This gives glycerin an affinity for the body, making it an excellent carrier for herbs. (Nature’s Answer only uses “vegetable glycerin” in their products.) Another advantage of using glycerin over alcohol is that glycerin serves to protect and preserve the potency of the herbal extract in the bottle over the life of the product longer than alcohol would. Since alcohol easily evaporates, it can lose its effectiveness as a preservative for the herbal constituents as the amount of the alcohol in the bottle decreases. Glycerin, due to its viscosity (thickness) aids in maintaining the freshness and potency of the herb for the life of the product. Finally, glycerin has the added advantage of acting as a sugar-free natural sweetener, thus making the taste of some bitter herbs more palatable.

    Nature's Answer®, the pioneer of the alcohol-free extraction process, is proud to offer a comprehensive line of both single herb extracts and combination herbal formulas that do not contain alcohol.

  • These statements have not been evaluated by the FDA. They are not intended to diagnose, treat, cure or prevent any disease.



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    Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story
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    Date: June 29, 2005 09:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story

    Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story

    The hoodia landscape has been unnecessarily clouded recently thanks to the misinformation circulating about concentrated extracts and socalled “100%” hoodia powder. Most of the information is highly subjective, with no studies whatsoever to support claims that socalled “pure” powder is more efficacious than 20:1 concentrated extracts. In fact, purporting to offer 100% hoodia powder is a dubious claim at best, with some groups offering little in the way of solid evidence that theirs is actually authentic Hoodia gordonii grown in South Africa and imported to the United States legally with proper permits. Propagating the false notion that “more is better” is a risky, uncertain gamble if you’re not precisely sure what exactly you’re getting more of! At Source Naturals, a trusted company with years of experience and demonstrated excellence in nutritional supplements, we believe that nothing tops quality assurance.

    Extraction – The Bottom Line

    Much of the misunderstanding surrounding hoodia extracts directly corresponds to a common misperception that the word extract is mutually exclusive to standardization – a method of extraction that isolates and removes a constituent part of an herb or botanical for use in supplements to control potency. Unfortunately the ambiguity of the term “extract” in relation to hoodia products has led to uninformed claims that hoodia extracts somehow contain less essential Hoodia gordonii plant parts, which is patently false, and underscores the inherent confusion as to how high-quality concentrated hoodia powder is actually produced. Simply put, many of the truly effective hoodia products on the market are, by their very nature, extracts – whether they claim to be or not. That is because the concentration process by which the whole parts of the hoodia plant become dried powder is an extraction. Calling it anything but an extract would be, frankly, disingenuous.

    The Process

    Hoodia gordonii is a succulent containing excess moisture that needs to be removed in order to make an effective, concentrated powder. The process by which that moisture is removed to yield the powder is called an extraction. This process, however, is different from standardized extraction. This process does not remove a single component from the plant; rather it separates the water from the solid parts of the plant, making a concentrated powder for a more powerful, effective product.

    The End Result

    The raw materials used to make HOODIA EXTRACT have not been added to, nor have we attempted to specifically extract any constituent parts of the plant to regulate potency. What we have done is taken high-quality, authentic, certified material from one of the industry’s most respected suppliers of Hoodia gordonii and held it to our own high standards of Total Quality Assurance (TQA™) in making a supplement with 20 times more functional hoodia than had we ground the plant up water and all. By putting it through stringent testing procedures in our quality control lab we have assured our product’s quality and efficacy. The Hoodia gordonii we receive is carefully scrutinized; put through High Performance Thin Layer Chromatographic (HPTLC) analysis for authenticity, and microbiological screening for contamination, as well as other rigorous laboratory PROTOcols.

    Quality = Results

    When you buy Source Naturals HOODIA EXTRACT, you can be assured that you’re not just getting an effective, natural dietary supplement, you’re getting part of an almost 25- year old tradition in providing quality products that support your good health. So before you buy into “more = better,” remember the Source Naturals edict: Quality = Results. Source Naturals – dedicated to excellence, committed to you.



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    Well Child - For a Healthy Winter
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    Date: June 21, 2005 05:13 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Well Child - For a Healthy Winter

    Well Child - For A Healthy Winter

    By Lesley Tierra, L.Ac.

    As summer turns to fall and then to winter, the nights turn cold and the days brisk. This is a challenging time physiologically as our bodies, especially those of children, try to adapt to the changing climate. Coming into the Fall and Winter seasons, many people continue to eat and dress as if it were still summer, causing the body to work even harder at maintaining homeostasis. This is a special consideration for children who have the added challenge of being exposed to numerous other children in school and day care centers. This requires parents to be prepared by making sure your herbal health care chests are well stocked. One product worthy of having on hand is Well Child by Planetary Formulas, an echinacea-elderberry herbal syrup, specifically designed for the needs of our youth during the winter season. Well Child was developed by Michael Tierra, L.Ac., O.M.D. in the East-West Traditional Chinese Medicine Clinic in Santa Cruz, CA. Michael has been a practicing herbalist and licensed health professional for more than 35 years. His more than three decades of experience are represented in all his formulas, which have stood the test of time in his practice with literally thousands of clients.

    Key Herbal Elements

    * Echinacea purpurea leaf and root: No other herb is as widely used for winter immune health as echinacea. Originally used by Native Americans of the Plains and introduced to Eclectic physicians in the 1800's, echinacea has become one of the most widely researched botanicals in modern times. While the clinical findings of many studies have been mixed, there is substantial pre-clinical evidence demonstrating its ability to stimulate various immune responses, such as increasing macrophage, phagocytic and natural killer cell activity. Most of the clinical trials that have utilized PROTOcols and dosages similar to those used by professional herbalists have reported positive findings with regard to its immune-enhancing effects. Echinacea is also very safe. * Elderberry (Sambucus nigra): Whereas echinacea reigns supreme as North America's primary wintertime botanical supplement, the berries of elder have a similar reputation in Europe, where it is widely used in cordials. Most research on elderberries has been conducted in Israel, where it was found to contain potent immune-stimulating compounds as well as powerful antioxidant activity. It makes one of the most delicious proanthocyanidin-rich syrups, so it is an ideal wintertime supplement. In Western herbal terms it is classified as a warming diaphoretic, which makes it ideal in combination with echinacea as a first line defense against the cold winds of winter. * Honeysuckle flowers (Lonicera spp.): Honeysuckle flowers are among the most widely used botanicals in Chinese herbalism for wintertime health. They are a key ingredient in the legendary classic Chinese formula Yin Chiao, which is perhaps the most frequently prescribed of all Chinese herbal supplements. Honeysuckle flowers are rich in a host of unique flavonoids which likely contribute to their health-promoting effects. These key ingredients are combined with cinnamon twig, chamomile flowers, catnip, lemon balm, and licorice root in a great-tasting syrup base of purified water, vegetable glycerin, and honey, along with extra vitamin C.

    Clinical Experience

    At the East-West Clinic, we have experienced dramatic positive results when giving Well Child. Luckily, this combination of botanicals tastes good. In addition, Well Child is formulated in a tasty glycerin base with added honey. The result is a liquid that is easily taken by most children. Because of the honey, we do not recommend Well Child for children under two years of age, unless it is subjected to boiling water. We also recommend specific dietary changes, including the avoidance of cold and raw foods during the cold season, eating plenty of broths, avoiding dairy, and eliminating simple sugars from the diet while ensuring the intake of adequate fluids.

    References

    Chang HM, But PP. 1986. Pharmacology and Clinical Applications of Chinese Materia Medica. World Scientific. Singapore. Mumcuoglu M. 1995. Sambucus: Black elderberry extract. RSS Publishing, Inc. Skokie, IL. Upton R, Graff A (eds.). 2004 Echinacea purpurea root: Monograph of the American Herbal Pharmacopoeia. Scotts Valley, CA.

    Lesley Tierra L.Ac., Diplomate in Chinese Herbalism (NCCAOM) is a California state and nationally certified acupuncturist and herbalist. She has been practicing as a primary health care provider with her husband, Michael Tierra, in Santa Cruz, California for almost 20 years. Lesley combines acupuncture, herbs and food therapies in her work. She is the author of several books, including Herbs of Life, published by Crossing Press, and is co-author, with Michael, of Chinese Traditional Herbal Medicine. Lesley is also the director of the East-West School of Herbal Medicine, and has taught at schools throughout the United States and England since 1983.



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    Modified Citrus Pectin (MCP) and Mercury Cleansing Programs...
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    Date: June 21, 2005 05:02 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Modified Citrus Pectin (MCP) and Mercury Cleansing Programs...

    Modified Citrus Pectin (MCP) and Mercury Cleansing Programs

    by Isaac Eliaz, M.D., M.S., L.Ac.

    Modified Citrus Pectin (MCP) is a dietary supplement derived from the peel and pulp of citrus fruit. MCP is mostly known for its positive effects on cellular health. Recently, however, clinical research on MCP has produced exciting results for its use as a gentle chelator (eliminator) of mercury and other heavy metals. Some of the expanding clinical applications for MCP include:

  • * Detoxification; reduction of heavy metal body burden
  • * Supports normal cholesterol levels
  • * Immunomodulation enhancement

    The Problem with Mercury

    Recent news on mercury is particularly concerning for the U.S. population. In March 2004 the EPA issued a press release reporting nearly all fish contained traces of mercury. Some samples contained levels high enough to harm an unborn baby or young child's developing nervous system. These findings prompted the EPA to issue a warning to women who may become pregnant, pregnant women and nursing mothers advising them to eat only two meals of fish per week that are thought to have lower levels of mercury.1 In their most recent update (August 2004), the EPA issued a warning that 1/3 of the nation's lakes and 1/4 of its river ways are contaminated with toxic levels of mercury and other contaminants, and warned pregnant women and children against consumption of fish from these sources. Additionally, a National Academy of Sciences panel definitively warned that some children who had been exposed to mercury while in the wombs of their mothers were at risk for becoming those children "who have to struggle to keep up in school and who might require remedial classes of special education." The risk of mercury toxicity from fish has reached epidemic levels. Two studies have further spurred on the concerns of mercury toxicity, as they both found women to have mercury levels that are 8-10% above what is considered safe.1,2 Furthermore, women who ate more fish were found to have higher levels of mercury. Another source of mercury toxicity may be amalgam dental fillings. Heavy metals, in conjunction with the abundant presence of environmental toxins and xenoestrogens, constitute a dangerous insult to the body through DNA damage, hormonal modulation, immune suppression, oxidative stress, and cellular irritation.

    A New Application for MCP Use: Heavy Metal Detoxification

    The standard western medical approach for removing mercury from the body to treat mercury toxicity is chelation. This procedure is performed with harsh chelators that can cause multiple side effects while potentially robbing the body of some of its essential nutrients. While this may be the routine and most beneficial procedure when facing a serious toxicity problem, are there other, gentler ways to reduce mercury levels? Two recent clinical studies have found that MCP may be a promising new dietary solution for reducing heavy metal load. In one recent clinical study, MCP was administered to a group of volunteers, and baseline levels of their total body mercury burden were measured and then compared against levels after treatment with MCP (15 grams of PectaSol® daily) for four months. The results showed a significant average decrease (over 60%; p=0.03) in the total body mercury burden after treatment with MCP3 In an earlier study, PectaSol® was given to patients and proven to increase urinary secretion of heavy metals such as lead, mercury, cadmium and arsenic.4 Both studies concluded that MCP may be a promising alternative to the harsher intravenous chelating therapies as MCP was found to be both effective and free of any side effects.

    How MCP Works as a Gentle Chelator

    Pectins are natural gelling agents, binders, thickeners, and stabilizers in foods. They mostly consist of galacturonic acid and galacturonic-acid methyl esters with average molecular weights from 50,000 to 150,000 daltons. High-methoxy (HM) pectin has at least 50% DE (degree of esterification) or greater, while a low-methoxy (LM) pectin?s DE is 50% or less. For systemic chelation of heavy metals, pectin is modified to a low molecular weight, and low-methoxy content. My observation from using MCP as a detoxification agent in my clinic is that it works as a gentle chelator in the bloodstream and it is very useful for ongoing use. Because fish are still recommended as part of a healthy diet and an essential source of certain nutrients (essential fatty acids like DHA), mercury levels are also becoming a widespread health concern. It is a Catch-22 for dietary health. As the widespread environmental cleanup of mercury is unlikely in the short-term, the medical community should develop methods to treat toxicity or reduce high body levels of mercury body burden. One approach is the use of traditional and alternative medicine cleansing programs along with the use of dietary supplements such as MCP that may act as gentle chelators. For chelation purposes, 5-15 grams of MCP should be taken per day depending on mercury levels for one year. Maintenance at 2-5 grams per day thereafter is usually sufficient. In my practice, I use 15 grams per day or 15 grams per day in the first 3-5 days of the month and 5 grams per day for the remainder of the month. MCP is generally regarded as safe and is well tolerated. Reported side effects have been rare, but may include mild and transient gastrointestinal discomfort.

    References:

    1-CDC Press Release: Blood and Hair Mercury Levels in Young Children and Women of Childbearing Age-United States, 1999 (see:/media/mmwrnews/n010302.htm#mmwr3) 2-Schober, SE, Sinks, TH, Jones, RL et al. (2003) Blood mercury levels in US children and women of childbearing age, 1999-2000. Journal of the American Medical Association. 289(13) :1667-74. 3-Eliaz, I. (2004) Modified citrus pectin (MCP) in the treatment of cancer. Paper presented at: The American Chemical Society Annual Meeting; Philadelphia, PA. 4-Eliaz, I. and D. Rode (2003). The effect of modified citrus pectin on the urinary excretion of toxic elements. Fifth Annual Conference of Environmental Health Scientists: Nutritional Toxicology and Metabolomics, University of California, Davis.

    --------------------------------------------------------------------------------

    Isaac Eliaz, M.D., M.S., L.Ac., is a pioneer in the field of integrative medicine and founder of Better Health Publishing®, an education-based company that provides health care professionals, consumers and other interested parties with scientific research on integrative medicine. He is a respected author, clinical practitioner and frequent guest lecturer on integrative medical approaches to health, immune enhancement and cancer prevention and treatment. Since 1991, Dr. Eliaz has maintained a busy private practice in Sebastopol, California, and is the current medical director of the Amitabha Medical Clinic and Healing Center (email:information@amitabhaclinic.com) which focuses primarily on integrative and holistic PROTOcols for cancer patients as well as those with chronic health challenges.



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    Go Green - green foods may be the SWAT team that sets you free...
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    Date: June 12, 2005 05:27 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Go Green - green foods may be the SWAT team that sets you free...

    Go Green by Chrystle Fiedler Energy Times, December 4, 2003

    If you feel like your busy life is holding your health hostage, green foods may be the SWAT team that sets you free. "Green foods are worth a king's ransom as far as your health is concerned," says Betty Kamen, PhD, author of Betty Kamen's 1,001 Health Secrets (Nutrition Encounter). "Green foods capture solar energy, using it to produce chlorophyll, which gives it its distinctive green color. Since we obtain our food by eating these plants or by eating the animals that eat these plants, this process is the source of human life."

    "Green foods are renewal foods," says Ryan Bradley, ND, of the Bastyr Center for Natural Health in Kenmore, Washington. "They help to counteract the nutrient depletion caused by stress and by caffeine intake. They're nutrient dense, grounding, balancing, and soothing in their energetic nature."

    Ideally, your meals should supply you with greens, but "...99.9% of the population doesn't get three to five [daily] servings of leafy green vegetables like kale, collard greens and spinach," says Jordan Rubin, NMD, PhD, CNC, author of Patient Heal Thyself (Freedom Press). Green foods can bridge that gap.

    "Green foods have become popular because it's a convenient way to get your servings," says Dr. Rubin. "You get the equivalent of two large salads with one serving of powdered green food. It's nutrient dense and low calorie so it's a great addition to any diet. It satisfies the brain so you don't feel hungry."

    "Everyone can benefit from green food supplementation," adds Dr. Kamen. "It's a concentrated supplier of everything that's good about vegetables."

    Chlorophyll for Health

    The key ingredient of green foods is chlorophyll, the green blood of plants. The benefits for humans from chlorophyll can be profound. A study of individuals at high risk of developing liver cancer because of their exposure to environmental toxins showed a 55% reduction in noxious compounds when these people supplemented their diets with a semi-synthetic chlorophyll derivative with properties similar to those of chlorophyll (Proc Natl Acad Sci USA 2001 Dec 4; 98(25):14601-6).

    "This research supports the long-standing notion that chlorophyll, and green foods, can play a role in detoxification in the liver, and thus 'cleansing' the blood," says Dr. Bradley. "It's a good addition to any detox PROTOcol. Test tube evidence also suggests that chlorophyll inhibits mutations in human cells."

    Chlorophyll is antimicrobial and anti-inflammatory. It can help fight anemia, improve digestion and elimination, and act as a mild diuretic. It also helps friendly bacteria in the gut reproduce and thereby possibly boost immunity.

    Green, Green Grasses

    Fast-growing plants, such as wheat and barley cereal grasses, contain the most chlorophyll and the deepest green color.

    "Wheat grass was one of the country's first multi-vitamins," says Dr. Rubin, who is also the author of Restoring Your Digestive Health (Twin Streams Health). "Certified organic cereal grasses pull a vast number of nutrients from the soil."

    "The solar-powered factory in the leaves of the young grass plants is almost beyond comprehension," says Dr. Kamen. "Sprouted grains have exceptional nutritive value and high amounts of certain vitamins and minerals."

    Spirulina Time

    The blue-green microalgae spirulina is a chlorophyll powerhouse.

    "Spirulina is high in protein, up to 65%, and the blue pigment of this blue-green algae, phycocyanin, has antioxidant, antiviral and antifungal properties," says Dr. Rubin.

    Like other greens, spirulina can help you cut calories. "When you nourish the body and the brain with nutrient-dense and low-caloric food, it satisfies that impulse to keep eating." Spirulina is also high in B vitamins such as riboflavin, niacin and pantothenic acid, all commonly depleted nutrients. B vitamins are critical players in overall metabolism, and are vital to nerve and adrenal function.

    Spirulina contains the minerals potassium and magnesium, plus iron. "It's been scientifically validated that [spirulina's iron is] comparable to the absorption from an egg," says Dr. Bradley. "It may benefit patients that are anemic. It's also a great choice for vegans who are looking for plant sources of iron."

    In addition, the spirulina compounds called phycocyanins may control inflammation and lower the risk of cancer.

    "Spirulina stimulates the part of the immune system [natural killer cells] responsible for our ability to fight off viruses and survey our tissues internally and detect and kill cancerous tissue," says Dr. Bradley.

    Chlorella Benefits

    Like spirulina, chlorella stimulates your natural killer cells to fight bacteria and viruses, and to strengthen your defenses.

    "Chlorella is the richest food on the planet in chlorophyll," says Dr. Kamen. "It's also high in protein and rich in beta-carotene and minerals.

    "One of the truly amazing facts about chlorella is its ability to oxygenate the blood," Dr. Kamen continues. "If your blood doesn't have enough oxygen, you can become listless and lethargic. Chlorella actually increases your hemoglobin, the oxygen transporter in your blood, so there is more oxygen present. It provides the necessary fuel for making healthy cells, and the result is renewed energy and vitality."

    Both spirulina and chorella also contain omega-6 fatty acids that have anti-inflammatory benefits and can improve the behavior of your blood vessels. In addition, they provide vitamin B12.

    Green Foods from the Sea

    Seaweed and other sea vegetables like kelp offer a green foods bonanza. Seaweed is low in calories but, like spirulina, offers a wealth of nutrients.

    "Most seaweed provides a rich supply of many essential nutrients, including protein, calcium, iodine and zinc," says Bradley Willcox, MD, co-author of The Okinawa Program (Potter). "Iodine is essential to the function of the thyroid gland, which needs it to make hormones that regulate your body's metabolism. Lignans, the cancer-fighting phytoestrogens have been found in high quantities in seaweed, mostly kelp, which could conceivably provide some protection against certain types of cancers."

    Lower rates of breast cancer were reported in Japanese patients eating a diet high in kelp (Nutr Cancer 1983; 4:217-22). Kelp has also been shown to reduce DNA damage induced by several known carcinogens (Mutat Res 1993; 303:63-70).

    Sea greens contain omega-3 fatty acids, fats that boost heart health. "Sea vegetables may prove to be a more sustainable source of omega-3 fatty acids than the dwindling fish populations," says Dr. Bradley.

    To incorporate sea greens into your diet, start by putting them on your lettuce and tomatoes.

    "Sea vegetables can make a great addition to salads," says Dr. Bradley. "They're high in nutrition and add flavor because of the sodium. They also add texture, giving salads more crunch."

    Other ways to green up your diet:

    * "Kelp comes packaged in three-foot-long dried strips and is prepared by cutting the long strips into smaller two- to three-inch strips and boiling them for about ten minutes. You remove the kelp, and then you can use the broth in soups, salads and other dishes. Kelp simmered with vegetables or tofu and served in miso soup is an Okinawan favorite," says Dr. Willcox.

    * Wakame (one of Dr. Willcox's favorites), a type of kelp, has a taste and appearance that may remind Westerners of spinach lasagna.

    * Nori seaweed can be used to wrap sushi and rice balls and also to season salads, soups and noodles.

    "Seaweed tastes great and if used wisely, should not tip you into sodium overload," says Dr. Willcox.

    Go for the Green

    More and more people are realizing and enjoying the benefits of green foods. Dr. Bradley recommends keeping your green foods consumption simple. Add powdered greens, dried tablets and liquids to juice, mix them into smoothies or a protein shake, and sprinkle the powder on salads. Mixed in water, greens can be used as a morning tonic and help replace some of the nutrients like magnesium and B vitamins depleted by coffee and other caffeinated beverages, which act as diuretics.

    "Incorporate a green drink into your diet once or twice a day," says Dr. Bradley. "It's the least expensive (health) insurance policy you can have."



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    The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease
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    Date: June 09, 2005 05:22 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease

    The Latest Breakthroughs in Garlic Research

    on Cancer and Cardiovascular Disease

    Presented at the 2005 World Garlic Symposium

    Many of the world’s top-level scientists gathered in Washington D.C. this week for the 2005 Garlic Symposium, entitled, “Significance of Garlic and its Constituents in Cancer and Cardiovascular Disease.” The conference provided current scientific information about the effect of garlic and its constituents on health and performance. The symposium was held at the Georgetown University Conference Center on April 9-11, 2005.

    “For the first time in seven years authorities in various fields of garlic research from all over the world to provide the latest updates, specifically regarding aged garlic extract and its actions in diseased states including heart disease and cancer,” commented Dr. Matthew Budoff, M.D. cardiovascular researcher at UCLA. “Garlic has been used medicinally for thousands of years in virtually all ancient cultures. Now, new metabolic roles for garlic are being proposed and there are many promising lines of research.”

    Presentation highlights included:

  • • Clinical Intervention Trial and pre-clinical substantiation on Cancer using Garlic, presented by National Cancer Institute scientists, Mitchell Gail and John Milner Mounting evidence points to the anticancer properties of aged garlic extract and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis.

  • • Inhibition of Coronary Arterial Plaque Accumulation by Garlic, presented by Matthew Budoff, Harbor-UCLA Medical Center

    Effect of aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study that determined that the atherosclerotic plaque burden detected by electron beam tomography (EBT) changed significantly with the use of aged garlic extract, Patients in Dr. Budoff’s study were able to significantly lower their total cholesterol, blood pressure, homocysteine and LDL cholesterol oxidation levels with aged garlic extract supplementation.

  • • Influence of Garlic on Endothelial Dysfunction in Hyperhomocysteinemia, presented by Norbert Weiss, University of Munich in Germany Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute high homocysteine on endothelium-dependent brachial artery vasodilatation and on acetylcholine-induced stimulation of skin perfusion.

  • • Anti-glycation properties of aged garlic extract: possible role in prevention of diabetic complications, presented by Nessar Ahmed, Manchester Metropolitan University in England Aged garlic extract inhibited the formation of advanced glycation end products, which have been previously shown to increase the risk of diabetic complications ranging from heart disease to retinopathy, kidney failure, impaired wound healing and many more.

    “Garlic is turning out to be a major player in cancer and heart disease prevention and control, especially in combination with drug treatments,” said Richard Rivlin, M.D. of Strang Cancer Prevention Center at Cornell. “It’s also showing us that we can start early. It’s madness to treat cancer and heart disease in their advanced stages. We need to start early and aged garlic extract is an excellent way to do that.”

    Almost 400 scientific studies have been completed on aged garlic extract, done in major universities worldwide. These studies have focused on a variety of heart disease risk factors such as cholesterol, high blood pressure, homocysteine levels, inhibiting LDL oxidation, anti-platelet aggregation and adhesion, stimulating blood circulation; in addition to other studies on immune stimulation, cognitive effects, liver function and anti-tumor effects. .

    Abstracts

    PRECLINICAL PERSPECTIVE ON GARLIC AND CANCER. John A. Milner, National Cancer Institute, Rockville, MD 20892

    Mounting evidence points to the anticancer properties of fresh garlic extracts, aged garlic, garlic oil, and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis. A block in carcinogen activation through modulation of cytochrome P450-dependent monooxygenases and/or acceleration of carcinogen detoxification via induction of phase II enzymes likely account for some of this protection. The block in preneoplastic lesions and/or tumors in several sites suggests a generalizable mechanism. The efficacy of water- and lipid-soluble allyl sulfur compounds against chemical carcinogenesis appears comparable, although more studies are needed. A shift in sulfhydryl groups, redox status or enzyme catalysis may account for some of the phenotypic changes. They may also account for the observed hyperphosphorylation of specific cell cycle related proteins and histone hyperacetylation; both of which have been correlated with suppressed tumor cell proliferation. Several forms of allyl sulfur compounds are effective in blocking cell division and inducing apoptosis, but notable differences in the efficacy among these various compounds and across tumor types are evident. While the expression of many genes and proteins can be influenced by allyl sulfides; the challenge is to determine which is responsible for a phenotypic change. Additional studies are needed with more modest exposures and over prolonged periods and that utilize transgenic and knockout models to assist in the identification of molecular targets. Finally, additional research is needed to identify sensitive “effect” and “susceptibility” biomarkers that can ultimately be used to identify responders from non-responders.

    INHIBITION OF CORONARY ARTERIAL PLAQUE ACCUMULATION BY GARLIC. Matthew Budoff, Harbor-UCLA Medical Center, UCLA School of Medicine, California, USA

    Effect of Aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study to determine whether the atherosclerotic plaque burden detected by electron beam tomography (EBT) will change at a different rate under the influence of AGE or placebo. EBT can non-invasively quantitate the amount of coronary calcification and track atherosclerotic plaque over time. Nineteen of 23 patients completed the study PROTOcol. The patients were well matched for age, gender, statin use and cardiac risk factors. Patients underwent EBT and blood testing at baseline, and then again after 12 months of randomization. The average change in the calcium score (Volumetric method) ± SD for the AGE group (n = 9) was 7.5 ± 9.4% over the one year. The placebo group (n = 10) demonstrated 22.2 ± 18.5% annual progression, significantly greater than the treated cohort (p = 0.01). While there were no significant changes in cholesterol parameters, or C Reactive protein between the groups, high density lipoproteins and plasma homocysteine in the AGE group demonstrated a trend toward improvement compared to the placebo patients. Thus, although this is a small-scale trial, it demonstrates the potential of AGE to inhibit the rate of atherosclerosis (progression of coronary calcium), as compared to placebo over one year. Larger studies need to be performed to assess this potential anti-atherosclerotic therapy and the impact on coronary events.

    INFLUENCE OF GARLIC ON ENDOTHELIAL DYSFUNCTION IN HYPERHOMOCYSTEINEMIA. N. Weiss, N. Ide, T. Abahji, L. Nill, C. Keller, U. Hoffmann. Klinikum der Universität München, D-80336 Munich, Germany

    Endothelial dysfunction (ED) due to decreased bioavailable nitric oxide (NO) by increased vascular oxidant stress plays a critical role in the vascular pathobiology of hyperhomocysteinemia (hhcy). Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. We performed a placebo-controlled, blinded, cross-over study to examine whether AGE prevents macro- and microvascular ED during acute hhcy induced by an oral methionine challenge in healthy subjects. Acute hhcy leads to a significant decrease in flow-mediated vasodilation of the brachial artery as determined by vascular ultrasound, indicative of macrovascular ED, as well as a decreased number of recruited nailfold capillaries during postischemic reactive hyperemia as determined by videomicroscopy, and to a decreased ratio of acetylcholine (endothelium-dependent) vs. sodium nitroprusside (endothelium-independent) iontophoresis induced skin perfusion as measured by laser doppler flowmetry, indicative of microvascular ED. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute hhcy on endothelium-dependent brachial artery vasodilation and on acetylcholine-induced stimulation of skin perfusion. Whether or not this is accompanied by changes in biochemical parameters of ED is still under investigation. It is concluded that AGE may at least partly prevent a decrease in bioavailable NO during acute hhcy.

    Bibliographies

    David Heber, MD, PhD, FACP, FACN

    Professor, UCLA Department of Medicine - Division of Clinical Nutrition, at the David Geffen School of Medicine, UCLA, and UCLA School of Public Health; Director, UCLA Center for Human Nutrition; Director, NIH Center for Dietary Supplement Research in Botanicals (CDSRB); Director, NCI-funded Clinical Nutrition Research Unit; Vice Chair, UCLA Collaborative Centers for Integrative Medicine; Member, UCLA's Jonsson Comprehensive Cancer Center

    Matthew Budoff, MD, FACC

    Matthew Budoff, MD, FACC, is an associate professor of medicine at the UCLA School of Medicine and program director for the Division of Cardiology, as well as director of the Electron Beam CT Laboratory at Harbor-UCLA Medical Center in Torrance, Calif. He completed his undergraduate work at University of California, Riverside, and earned his medical degree at George Washington University in Washington D.C. Dr. Budoff’s efforts to identify and modify risk factors for cardiovascular disease using electron beam CT have been extensively published. His latest research focuses on the progression of arteriosclerosis.



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    What is Hoodia?
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    Date: June 09, 2005 10:39 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: What is Hoodia?

    Hoodia

    1. What is Hoodia? Despite its similar appearance, the cactus-like hoodia is characterized as a succulent plant, which is a member of the milkweed family. Though there are about 20 species within the family, the active ingredient of hoodia is found only in the gordonii variety native to South Africa's vast Kalahari Desert

    2. What assurances can be made that Source Naturals Hoodia Extract is authentic? Experts in succulent horticulture have helped ensure that the raw material Source Naturals uses to make Hoodia Extract is gathered from authentic Hoodia gordonii sources. From there, our supplier has an independent laboratory test the raw material, which is then issued with a certificate of analysis qualifying it as true Hoodia gordonii.

    Once Source Naturals receives the certified Hoodia gordonii from our suppliers, we hold it to our own high standards and Total Quality Assurance. By putting it through stringent testing procedures in our quality control lab, we've carefully scrutinized the material. Before it ever reaches the hand of consumers, our high-quality hoodia is put through High Performance Thin Layer Chromatographic (HPTLC) analysis for authenticity, and microbiological screening for contamination, as well as other rigorous laboratory PROTOcols.

    3. Could you explain the 20:1 ratio? 20:1 refers to the "wet to dry" ratio of the whole plant to concentrated powder. Hoodia gordonii contains an abundance of excess moisture that needs to be removed in order to make an effective, concentrated powder. The process by which that moisture is removed to yield the powder is an extraction. Basically, 20 pounds of whole plant is concentrated to one pound of the high-quality powder used to make our product.

    What this means is, we've made a supplement with 20 times more functional hoodia than had we ground the plant up water and all. When you buy Source Naturals Hoodia Extract, you're getting all of the usable plant parts of the Hoodia gordonii times 20, because we've packed a greater amount of the quintessential hoodia ingredients into a powerful, concentrated powder.

    4. Is a 20:1 concentrated extract more effective than 1:1 hoodia powder? We at Source Naturals certainly believe so. Unfortunately, the hoodia landscape has been unnecessarily clouded recently thanks to the misinformation circulating about concentrated extracts and so-called "100%" (1:1) hoodia powder. Most of the information is highly subjective, with no studies whatsoever to support claims that so-called "pure" powder is more efficacious than 20:1 concentrated extracts.

    The common selling point for those propagating a 1:1 hoodia product is the notion that "more is better" - which, when you think about it, actually benefits a 20:1 concentrated extract. Because the logic behind using the 20:1 concentrated extract is that, in supplementation, it's not practical to ingest as much of the whole plant parts of hoodia as the San did to get the potential benefits of the plant. In using the concentrated 20:1 ratio, we're able to pack 20 times the amount of usable hoodia into our Hoodia Extract. How much more could you need?

    5. Where was the hoodia in Hoodia Extract grown? On an approved farm in Northern Cape, South Africa.

    6. Who is our supplier? Due to obvious business considerations, we don't want to specifically name our supplier and alert competitors to our source. However you can be assured that we receive our Hoodia gordonii from one of the industry's top suppliers, who was among the first and only importers of hoodia licensed to sell and import the plant into the United States.

    7. I've heard there are sustainability issues with the plant. Is it endangered? It is true that the resources for Hoodia gordonii are limited due to early irresponsibility on those seeking to exploit the plant's benefits. However, Source Naturals Hoodia Extract has been produced with environmental sustainability in mind. We've made absolutely sure that only materials safely cultivated from the stems of seedlings grown on approved farms in South Africa have been used in making Hoodia Extract, not material indiscriminately picked in the wild.

    8. How should it be used? Take one to two tablets or capsules with an 8 ounce glass of water about an hour before eating a meal.

    9. Why does the label warning recommend consulting your health care professional before using this product if you are taking any prescription medication? This is a standard warning included on most Source Naturals product labels because generally it's a good idea to double check with your physician if you're taking prescription medication to make sure there aren't any special precautions you need to take while on the medication.

    10. Does it contain caffeine? No. There is no caffeine in Hoodia gordonii, and Source Naturals Hoodia Extract does not contain any added caffeine.

    11. Are there any side-effects? There are no known negative side-effects to taking hoodia products.



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    Mega H- Hydrogen (H-)The Fuel of Life
    TopPreviousNext

    Date: June 03, 2005 05:00 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Mega H- Hydrogen (H-)The Fuel of Life

    Our universe is composed of millions of compounds, all derived from just 106 atoms. Of these elements, hydrogen is the first and most fundamental.

    Hydrogen is also the most abundant element, comprising 90% of all atoms in the cosmos. In our sun and stars, hydrogen nuclei fuse to produce helium, the second element. This generates the enormous energy that powers life on earth. And just as hydrogen fuels the sun, so, in the human body, it is the essential factor in the electrochemical process that produces ATP, the energy molecule. Virtually all the millions of biochemical processes that occur every second of our lives are powered by ATP. These facts are well established. But they are so basic that, until now, they have been overlooked in the world of nutritional science. It took the dedicated research of Dr. Patrick Flanagan to harness the power of active hydrogen for health and human development.

    Introducing a revolutionary breakthrough in the field of nutritional science: MEGA H-™ Active Hydrogen (H-), the Fuel of Life.

    The Creation of Mega H-

    For 30 years Dr. Patrick Flanagan’s life work has been to discover the health and longevity secrets of the Hunza people of the Himalayas. It is believed a much greater percentage of people there live past the age of 100, with far less of the diseases that ravage the West. The locals claimed that their secret was the cloudy, mineral-rich water that rushes down from the Himalayan glaciers. In studying the properties of this Hunza water, Dr. Flanagan found that silica crystals dissolved in the water were able to hold negatively charged hydrogen ions (H-). These compounds are technically called silica hydrides. This makes Hunza water a power source, filled with the same active H- that powers the human body.

    Typically hydrogen has one positively charged PROTOn in the nucleus and one negatively charged electron orbiting the nucleus. The two opposite charges balance each other, resulting in no charge. Active hydrogen, on the other hand, contains two electrons orbiting the nucleus, creating a negative charge. It is this active hydrogen in its charged form that the body needs to carry out its crucial functions. Dr. Flanagan has recreated this silica hydride compound as MEGA H-™.

    Cellular Energy: ATP, Hydrogen and Mega H-™

    ATP, adenosine triphosphate, is composed of three phosphates. The breaking of the bond between the second and third phosphates releases the energy to power virtually all cellular processes. Amazingly, we all generate enough metabolic energy to produce our own body weight in ATP every day just to function! Every second, each of our approximately 50 trillion cells consumes and regenerates 10 million molecules of ATP.

    This massive energy generation (ATP production) is the fundamental core function of every human cell. Without it, basic activities such as cellular repair, and protein, enzyme, hormone and neurotransmitter synthesis would not occur. DNA repair and cell reproduction would cease. Thoughts, feelings, communication, and our ability to experience the world through our senses and change it through our actions would stop. The negative implication of poor energy generation for our health and vitality levels is significant. Many factors such as aging, poor nutrition and pollution can impede this critical energy generation. Negatively charged electrons from hydrogen are the source of the energy needed to generate this staggering amount of ATP. This energy production takes place in the mitochondria of the cells at the final stage of the Krebs Cycle, called the electron transport chain. Typically, the hydrogen comes from the breakdown of carbohydrates from food, which yields hydrogen as well as carbon and oxygen. But MEGA H-™ is an alternative, electron- rich source of hydrogen to power energy generation. In fact, MEGA H-™ has been shown to double the production of ATP and NADH, according to in vitro studies. (NADH is the coenzyme form of vitamin B-3, niacin, that carries hydrogen to the production site of ATP.) If this alone was all that MEGA H-™ could accomplish, it would be the most significant nutritional compound yet discovered. But its properties go far beyond energy generation. It is the body’s most efficient and effective antioxidant. MEGA H-™ also increases cellular hydration and the uptake of nutrients into each cell by lowering the surface tension of water (making water “wetter”). And it can improve athletic performance by lowering lactic acid levels after strenuous workouts.

    Aging and Antioxidant Defense

    Energy Decline: As we age, there is a decrease in our bodies’ ability to generate cellular energy—and oxidative damage may be a primary factor. Many scientists now accept the theory of aging first proposed by noted scientist Denham Harman, M.D., Ph.D., who argued that “aging changes are induced by free radical reactions, largely initiated by the mitochondria … the rate of damage to the mitochondria determines our life span.” Why is this? While oxygen is necessary for human life, the very act of breathing generates free radicals. Our mitochondria— tiny energy production plants—are the chief source of oxidants produced in our bodies. It is believed these oxidants damage the mitochondria in which they are produced, including the inner mitochondrial membrane, which is the site of ATP production. This would seriously impair the ability of mitochondria to meet cellular energy demands. The result: signs of normal aging such as impaired memory, hearing, vision and stamina.

    DNA Damage: Oxidants also can damage the cell’s DNA. Hydroxyl radicals cause DNA strands to break; if breaks occur in both strands of DNA, the cell cannot repair the damage and will die. Normally, the body has mechanisms to correct or remove damaged cells. However, as we age and cellular energy production declines, the ability to correct these errors is significantly reduced. Left unrepaired, DNA errors may be passed on when cells divide. Over time, these errors can silently accumulate, leading to cellular changes that go unnoticed until body system imbalances become evident.

    World’s Most Elemental Antioxidant

    MEGA H-™ may be the world’s most powerful antioxidant. It is possible to measure the Oxidation Reduction Potential (ORP) of any compound. This rating, which measures the number of electrons present in relation to PROTOns, ranges from (plus) +1,200 to (minus) -800 millivolts; the stronger an antioxidant is, the closer its ORP would be to -800. The more positive the ORP reading, the fewer the number of available electrons from active hydrogen. In chemistry, active hydrogen is defined as hydrogen with an extra electron, also known as the hydrogen anion, negative hydrogen or H-. The strongest natural antioxidants up until now, such as grape seed and green tea, have ORP’s of -100. But Mega H-™ has an ORP of -778 millivolts, as compared to distilled water, making it the most potent natural antioxidant available today. What’s more, MEGA H-™ is in a class by itself, compared to other antioxidants, due to its electrochemical structure. Free radi-cals—unstable molecules that are missing one or more electrons—damage cells by taking electrons from healthy molecules to balance themselves. When other antioxidants donate electrons to quench free radicals, they in turn become reactive free radicals and require electrons from other antioxidants to become stable. The new antioxidant also requires an electron to return to stability. This process continues, resulting in an inefficient and energy-consuming free radical cascade. But MEGA H-™’s negatively charged hydrogen molecule possesses two electrons instead of the typical one. This extra electron can be donated without generating the inefficient free radical cascade. Dr. Flanagan’s profound contribution was his discovery of a method for stabilizing and delivering negatively charged hydrogen (H-). Unlike taking other antioxidants, supplementing with MEGA H-™ provides a net gain of free radical-quenching electrons into the system.

    Additional Health Benefits

    MEGA H-™ has been the subject of additional positive research: Increases Cellular Hydration: Water is important to cells, interstitial fluids (surrounding joints, muscles and organs), and the matrix of blood. As the body’s primary fluid, water serves as a solvent for nutrients. Since water is used to carry nutrients into the cell, it is theorized that increased cellular hydration also increases the bioavailability of nutrients. Water also eliminates toxins and waste products from the body. From energy production to joint lubrication, all our systems depend on water. It has been theorized that aging results in cell dehydration. A study done by Gary Osborn and H. Salinas, M.D. of the Texas Institute of Functional Medicines suggests that silica hydride supplements like MEGA H-™ increase intracellular, extracellular and total body water levels. It is theorized they work by decreasing water’s surface tension, which allows water and nutrients to more easily enter cells and become available for use by the body. Assists In Exercise Recovery: During strenuous exercise, the oxygen supply to muscle cells is insufficient to meet energy demands. Muscle cells then turn to anaerobic respiration to continue to generate energy. This creates lactic acid, which diffuses into the blood, causing muscle fatigue, soreness and loss of endurance. A placebo-controlled study on six healthy males showed that blood lactate levels significantly decreased after exercise when silica hydride supplements were taken for one week before an exercise trial.

    The Scientist Behind Mega H-™

    This revolutionary approach to nutrition and health is the brain child of Dr. Patrick Flanagan. Dr. Flanagan was a child prodigy with an intense interest in electronics, biochemistry and physics. At the age of 12, he invented a guided missile and atom bomb detector. This technology was subsequently adopted for use by the U.S. government. At 14 he developed the Neurophone®. This device transmits acoustic information to the brain by means of radio waves into the skin, bypassing the eighth cranial nerve, and may allow some deaf people to hear. By the age of 18, he was named one of the Top Ten most promising young scientists in America by Life Magazine. Dr. Flanagan’s work with MEGA H-™ has its roots in his collaboration with Dr. Henri Coanda, a respected scientist who died in 1972. Dr. Coanda passed along his investigation into Hunza water to Dr. Flanagan. MEGA H- is the culmination of decades of research to bring the energizing and anti-aging benefits of active hydrogen (H-) to the world.

    Mega H-™

    Hydrogen (H-)The Fuel of Life

  • • The first active hydrogen supplement (H-), a rich source of electrons.
  • • Electrons from H- are a source of energy to generate the body’s staggering amounts of ATP (energy molecule).
  • • MEGA H-™ doubles cellular ATP and NADH in vitro.
  • • Theorized to be the most potent antioxidant in vitro.
  • • May decrease lactic acid levels after exercise.
  • • May increase cellular hydration.

    MEGA H-™ is the first supplement available in the natural foods industry to provide a large reservoir of freely available electrons to power the body’s diverse energy functions.



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    Milk Thistle and Liver Damage abstract ...
    TopPreviousNext

    Date: May 22, 2005 04:32 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Milk Thistle and Liver Damage abstract ...

    Silymarin Protects Against Liver Damage in BALB/c Mice Exposed to Fumonisin B1 Despite Increasing Accumulation of Free Sphingoid Bases

    Quanren He, Jiyoung Kim, and Raghubir P. Sharma,1 Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602-7389

    This study showed that silymarin prevented FB1-induced liver injury and the overexpressions of selected genes for TNF-superfamily and IFNg.FB1 increased free sphingoid bases in tissues via the inhibition of ceramide synthase (Merrill et al., 1993; Wang et al., 1991). Free sphingoid bases could mediate cell death following FB1 treatment (Schmelz et al., 339 SILYMARIN PROTECTS AGAINST FUMONISIN HEPATOTOXICITY TABLE 2 Activity of Serine Palmitoyltransferase (SPT) in Liver and Kidney of Mice Following FB1 Exposurea Treatment Hepatic SPT activity Renal SPT activity Control 186.2 6 21.4 325.4 63.5 FB1 267.5 24.6* 319.5 14.8 Silymarin 80.0 12.9*,# 220.3 19.4*,# Silymarin 1 FB1 71.0 15.6*,# 251.1 13.6 aActivity of SPT is expressed as pmol product/min. mg protein. Data are presented as mean SE. *p 5 0.05 compared to control; # p 5 0.05 compared to FB1 treatment. 1998; Tolleson et al., 1999). In contrast to its inhibitory effects on liver damage and selected gene induction, silymarin dramatically increased FB1-induced accumulation of free sphingoid bases. The FB1-induced alterations in mouse liver were similar to those reported previously employing similar PROTOcols (Sharma et al., 1997, 2003a,b). The only difference in treatments was the duration (3 vs. 5 days in former reports) and gender (females in the current experiments). Exposure of mice to FB1 caused the appearance of apoptotic cells in liver with no other noticeable alterations. The PCNA-positive cells were also increased in FB1treated mice.

    In conclusion, we have clearly demonstrated that silymarin plays a protective role in FB1 hepatotoxicity in a mouse model. These findings suggest a therapeutic potential of silymarin in fumonisin liver injury in humans or animals exposed to fumo-nisin-producing, fungus-contaminated feeds. The efficacy of silymarin in the protection from liver damage after long-term exposure to the mycotoxin still needs to be studied.



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    TopPreviousNext

    Date: May 09, 2005 06:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    It's in the Blood

    Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

    The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

    “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

    “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

    At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

    While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

    Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

    And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

    Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

    King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

    Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

    "Blur of Products"

    With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a PROTOcol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

    To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

    Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

    Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

    Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

    “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

    On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

    Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

    Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

    Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

    Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

    Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

    Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

    “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

    Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

    Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

    “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

    For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

    Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

    Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

    Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

    Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

    Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

    “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

    Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

    Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

    However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

    Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

    Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

    Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

    New Weapons

    There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

    With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

    Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

    “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

    Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/

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