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Want to get enough vitamin D? Try supplements or sunshine
August 27, 2018 09:53 AM
If you are a person that lacks in Vitamin D, there are a couple supplements OR all natural ways to help. According to the US Preventive Services Task Force, Vitamin D supplements are ineffective in preventing cardiovascular disease or cancer. In fact, some supplements may take up to years to see a results. An easier way to help increase Vitamin D, is to simply lay in the sun. Vitamin D is actually a hormone that resides in our skin and is triggered by the sun's radiation.
"By the end of 2017, we’ll know who got vitamin D and who got the placebo, and whether the vitamin D group had lower rates of those health problems than the placebo group."
Read more: http://atozhealthguide.com/index.php/2018/08/22/want-to-get-enough-vitamin-d-try-supplements-or-sunshine/
Okra is a gut-friendly vegetable you need to be eating more often
August 19, 2018 05:53 PM
Okra is so good for you. Many people do not realize the benefits of vegetables and what they offer you. People need to have vegetables as part of their daily diet due to the nutrients that they provide. Overall, they are so healthy for the mind and for the physical body. They help speed up the metabolism and allow for fats to be released from the body. The more people eat things like okra, the better they will feel!
"Multiple studies have also shown that the benefits of okra aren’t limited solely to improving overall digestive health. A study made by the Agricultural Research Service of the USDA indicated that okra, together with other vegetables like beets, asparagus, eggplants, and cauliflower, handled the binding of bile acids better than the reference drug cholestyramine."
Read more: https://www.naturalnews.com/2018-08-18-okra-is-a-gut-friendly-vegetable-you-need-to-be-taking-more-often.html
Sugar: A Dangerous and Addictive Drug?
October 12, 2017 10:14 AM
Sugar has been known to be addictive for a while. The body and brain can begin to crave it. It can cause many health problems as well if it is not controlled. Be careful not to consume too much sugar if you want to remain healthy. Your body will thank you. Sugar negatively affects many parts of it including the teeth. Diabetes can occur if you overindulge as well. A weight problem can also occur.
"Two hundred years ago, the average American ate 2 pounds of sugar per year. Today, we each eat about 152 pounds a year, according to the U.S. Department of Health and Human Services."
Read more: https://www.theepochtimes.com/sugar-a-dangerous-and-addictive-drug_2320725.html
What Is a Chiropractor? Surprising Facts About Chiropractic Care
September 05, 2017 09:14 AM
In recent years chiropractic services have been gaining a more positive outlook from doctors practicing traditional medicine. Doctors these days are more likely to refer a patient to a chiropractor for many reasons, such as treatment of migraine headaches, pain in the joints to problems with vision. Chiropractors are being more and more recognized as an alternative treatment to prescription drugs. Many people don't realize that chiropractors spend years in training making them a viable alternative for unwanted symptoms. Chiropractors are schooled in a variety of stress relieving treatments, such as herbal and nutritional remedies. Having regular adjustments by a chiropractor is also a good way to do preventative maintenance for your health.
"Restoring motion and alignment of the spine is the first step in helping the rest of the body to self-regulate, self-maintain and self-restore, due to the spine’s direct neurological influence on the rest of the body."
Read more: https://draxe.com/what-is-a-chiropractor/
Probiotics found to protect honey bees from toxic effects of pesticides
June 25, 2017 09:14 AM
Honeybees are necessary for our agriculture they provide an air replaceable service when they cross pollinate crops. Unfortunately, the population of bees has been decreasing and human made a pesticide are a major reason. Studies conducted in fruit flies and early studies and honeybees show that a probiotic can be used to negate the effects of pesticides. Just stopping pesticide use seems a simple solution but crops could also be devastated, that's why the study into probiotics is so important.
"According to a recent study from Lawson Health Research Institute and Western University, probiotics can protect honey bees from the fatal side effects of pesticides that people use to protect their crops."
Read more: http://www.naturalnews.com/2017-06-22-probiotics-found-to-protect-honey-bees-from-toxic-effects-of-pesticides.html
9 Natural Ways To Combat Depression That Actually Work
March 17, 2017 11:44 AM
Chronic depression should not be left untreated. Cost of treatment is a real concern, particularly if you are uninsured or unable to meet high deductibles. Fortunately, there are alternatives. Look for the free or low cost resources in your community. Community counseling services or support groups are some examples of low cost or free access to help. Self helps in the form of journal writing or meditation should be considered. Take advantage of sunlight, exercise, and a balanced diet. Finally, know the number for a national crisis hotline and recognize help is waiting for your call.
"Some universities across the nation offer community counseling services with graduate students in their psychology departments."
Read more: http://www.thealternativedaily.com/natural-ways-to-treat-depression/
September 17, 2014 05:25 PM
What is a Maca Root?
Maca Root is one of the roots and tuber harvests of higher protein content. Until late years, this nutritious base of the Andes was little or nothing known for the lion's share of the individuals thereof, Peru (aside from the tenants of the Andes) and obviously overlooked by whatever is left of the world.
Maca (otherwise called Peruvian Maca or Maca Andina) has an astonishing quality to develop to remarkable statures: from 3800 to 4800 meters high in the most cold Andes mountains, where temperatures are amazing, from exceptional hotness morning to ice on the night, frigid winds, snow and persevering high power of daylight. In this antagonistic region, where there is little oxygen, there is uncommon vegetation develop just potatoes and maca sharp. There are no trees, no plants, just a couple of centimeters tall.
This tuber, irrelevant part of the tuberous root size and state of a typical radish, is effectively dried under the sun and keeps up its nutritious qualities, with elevated amounts of iron, for a few years stockpiling. It is brilliant nourishment and Incas additionally utilized it for its richness improving activity and its impact on sexual conduct.
There have been various effective studies on the action manure Peruvian maca creatures and people. In 1980, researchers from Germany and North America who were doing investigations of the herbs in Peru, rekindled enthusiasm toward its momentum Maca, naming it "the lost products of the Incas."
A percentage of the elements that have been recognized: amino acids, proteins, vitamins, minerals, follow components and auxiliary metabolites.
Maca - History:
Anthropological confirmation has been found in the development of maca in Peru since 1600 BC. The Incas considered Maca as a blessing from the divine beings. They additionally develop maca as nourishment, Lamac - developed in the Andes utilized for religious Services and custom moves. Spanish accounts report that amid the victory of Peru, creatures brought from Spain not play ordinarily as of right now, the locals cautioned the vanquishers who nourished their creatures with maca, with what they got the levels of typical generation.
Concerning the stretcher, Father Cobo, amid the pilgrim time, he said: "Maca develops in the most rough and frosty of the good countries where there are chances to develop any plant sustenance."
Maca - Morphology and plant science
Maca is a biennial plant statures conduct, being pollinated toward oneself, cleistogamous, with a five-month conceptive stage and with a blossom that keeps going two roots.
Maca Root: Roots have shades extending from light yellow to dark through the tan, purple, and so on with sizes of 3-6 cm. transverse measurement of 4-7 cm. longitudinal, in the same way as a radish (reversed cone). The root is first in the improvement of items. There is no true distinction in taste or substance organization as the color of the root.
Stem: Short, subtle, in the same way as a carrot or radish.
Leaves: rosette, made with flanges sheath, petiole length with the top leveled. Limbo compound, has a length of 6 to 9 cm; the basal and cauline pinnatifid are somewhat lessened.
Inflorescence: group compound and infrequently basic. The blooms structure bunches, are helper bisexual, actinomorphic, green light and little, white pre-flowering calyx and corolla with 4 free petals somewhat bent at the peak.
Soil grown foods: units somewhat amagrinado. With a solitary seed in each one cell, ovoid, yellowish-red, 1-2 mm. wide.
Maca – Cultivation
Cultivola Maca is developed fundamentally for its tuberous root is naturally known as hipocolito (eg radish, turnip). The maca plant has the astonishing quality to develop to unprecedented statures (from 3800 to 4800 meters) in the unfriendly Puna Peruvian where temperatures are great: the serious high temperature of the morning to the sub zero frost of the night.
The puna is a pleasant yet great condition in this environmental locale is uncommon vegetation, just potatoes become astringent and maca. The air contains little oxygen, the sun is amazingly exceptional and extremely solid winds, it is consequently that no trees and plants have just a couple of centimeters tall.Maca planting is carried out from September to December. The seeds are scattered in the fields to be reaped in 6 to 8 months. After Recolta the roots to dry in the sun for 2 months, amid which they lose 75% of its unique weight. This moderate drying methodology causes the maca change of taste: an intense hot taste with a caramel flavor. The dried root could be put away for 4 years without losing its properties.
The Best Diffuser
May 03, 2014 04:45 AM
What is a diffuser
A diffuser can be defined as a flow of passage in wind tunnel that decelerates as a stream of gas or liquid from a place of high concentration to a place of low velocity. Diffuser works by breaking down essential oils into tiny molecules then directing them into the air to feel a place. As the oils are being broken down, they release natural ozone and they freshen and improve the quality of air. The particles stay in air for hours depending on how much oil is used and long the diffuser was on.
Different types of diffuser
Diffusers vary according to how they works. Different types of diffusers include ultrasonic, evaporative and nebulizer. Each has its purpose. But ultrasonic is a notch-higher than all of them. Having knowledge on differences between them can help you make a good choice. Ultrasonic diffuser is mostly preferred for those who want smaller particles and higher lung absorption.
The ultrasonic is different from the rest because it does not need heat or an air pump to disperse the essential oils into the air. It performs its function by the use of a vibration from a disc that is found underneath of the oil reservoir. This disc vibrates at a high speed that makes the essential oil to break into micro invisible particles. Others like nebulizers will force the essential oil into the air in very larger particles, which ends up in saturating the air much faster.
Ultrasonic vibrations disperse the essential oils more conservatively. This will save you much money at the end and you are only going to use as much oil as necessary. This can also be useful if you only want to add a small amount of essential oil to your room. If you use nebulizers, you can easily over saturate your room, this can over whelm you, and it can lead you to an adverse response.
If you want a good diffuser that will give you a great and quality Service, then you need to go for ultrasonic. It is very much affordable and it will give you value for your hard earned money.
Does Mangosteen Fruit Have Healing Properties?
March 25, 2014 08:22 AM
What is a mangosteen
The Mangosteen fruit is usually a Hawaiian sapling, started in this Southeast Asian nation. This sapling evolves from 7 to twenty-five feet high. This rind (pericarp or maybe peeling) with the fruit can be serious reddish violet while ready. Mangosteen fruit can be related directly to other Hawaiian fruits, but it contains simply no regards to this mango. Mangosteen fruit need to be stored humid to practical until germination, the idea dies rapidly when permitted to fail. Mangosteen fruit presumed to get a combination of vitamin richness, antioxidant strength as well as probable impact regarding reducing the danger in opposition to people ailments. This mangosteen fruit need to be harvested within a warm setting because exposures to help temperature ranges beneath 40oF (4oC) can kill this seed. Regarding the with the mangosteen fruit, it ought to be famous which Mangosteen fruit, generally known because "the queen regarding Hawaiian fruit", was launched to help BRITISH inside 19thcentury. From what individuals claim, King Victoria sampled this fruit in 1891, which the woman observed the idea fantastic.
Benefits of mangosteen
This particular wonderful fruit has been recognized due to the healing qualities. This rind (pericarp) with the fruit offers an incredible variety regarding natural and organic substances, among which can be Xanthones as well as tannic chemical which explains why the idea because already been for dysentery given that ages. Scientific research done around the healing utilizes with the mangosteen fruit ensures that a few substances inside rind with the mangosteen could have a few benefits in opposition to breast cancers, cancer of the blood, digestive tract cancers and thus onward. There are guaranteeing tips regarding other possible benefits down the route with the extraordinary qualities of the fruit. You can end, which mangosteen can certainly become a member of more information on plants that can be seen as guaranteeing sources of brand new medications. This particular seed is regarded as to give the strongest cause of xanthones (a kind of antioxidant) that may Service the fitness of the complete human body. Thither are 20 various xanthones whole fruits that may produce potent physiological qualities.
Mangosteen research claims its compounds having antioxidant, anti-bacterial, anti-tumor action and essentially anti-inflammatory qualities. The item protects in opposition to no cost radicals by getting rid of bacteria, viruses as well as infection. The item reduces irritation as well as aids your body's therapeutic process. Mangosteen fruit features exposed to get an exclusive scope regarding potent people health improvements.
All about trace minerals.
March 18, 2014 10:26 AM
While much accentuation is put on the trace minerals that are discovered to be crucial to the human form, to be specific, calcium, iron, magnesium, phosphorous, and zinc, there are additionally follow minerals which help the figure to perform its normal schedules. Follow minerals are required by the constitution, yet just in little measurements. Moment measures of follow components can mean the distinction between poor and fitting health. A number of them perform distinctive, critical capacities which are needed by the constitution. In this article, we'll examine a portion of the diverse follow minerals that are of Service to people.
Iodine is advantageous to the human figure because of the way that it serves to control advancement and usefulness in the thyroid organ. This is a capacity of most extreme criticalness, as the thyroid organ is answerable for to such an extent. The generation of vitality inside the human figure, fortified digestion system, discourse capability, and solid hair, skin, and teeth are all because of a legitimately working thyroid organ.
Copper is an alternate essential follow mineral. It has been discovered to be vital for legitimate assimilation of iron in the human form. It additionally works with the cell reinforcement Vitamin C to help structure elastin, which is a substance utilized within the muscles of the constitution. Fitting bone development, and also the best possible building of red platelets are likewise made conceivable because of copper.
Manganese, in itself, is capable cell reinforcement. Notwithstanding performing the capacities of a cancer prevention agent, manganese is answerable for fitting breakdown of amino acids and vitality generation. Vitamin B-1 and Vitamin E are likewise influenced by manganese, as it helps the form to metabolize them legitimately. Also, sex hormone creation is controlled by manganese.
While of Service for all people, diabetics specifically profit from the best possible measurements of chromium. It helps insulin in the constitution to metabolize sugar, keeping glucose at a sensible level. Chromium is additionally answerable for serving to clean garbage out of our conduits, lessening cholesterol and triglycerides.
Potassium works in pair with sodium in regulation of the physique's waste procedures. It animates the kidneys to help free the assemblage of harmful waste. Heart rhythms might additionally be stabilized by getting the correct dose of potassium. It is likewise known to encourage send more oxygen to the mind, which can bring about clearer considering.
Selenium is an alternate follow mineral that has critical cancer prevention agent properties. Some therapeutic reviews have demonstrated that a fitting selenium admission may bring about a diminished shot of contracting bosom, lung, colon and prostate malignancy.
The trace minerals recorded above are simply a portion of the more applicable follow minerals. There are numerous distinctive follow minerals that your constitution requirements and it might take truly a long rundown to depict every one of them. To get all the minerals you need, make sure to consume your everyday necessities of products of the soil. This sustenance’s hold probably the most vitamin and mineral-rich mixes accessible, and are beneficial to consume, to boot!
What's So Special About Bentonite Clay?
March 09, 2014 10:46 PM
What is bentonite
Bentonite Clay is mined around Fort Benton, Wyoming, from whence it got its name. Really Bentonite is found in ample supply in the northwest of the United States around Wyoming and Montana. Bentonite has been utilized by Indians and locals for a long time to cure a mixture of maladies by detoxifying the form.
Bentonite is really simply regular earth from the beginning. It is 61% silica additionally holds 18% aluminum, and little measures of iron, sodium, and magnesium. It is basic, with a ph of 8.3 to 9.1.
Bentonite works inside by drawing in a mixed bag of toxic substances from the gastrointestinal tract. The Bentonite Clay has a negative charge while the toxins have a tendency to have a positive charge. Along these lines there is the fascination of the toxins to the dirt. When these are assimilated, the figure wipes out the earth and toxins and you are healthier
How Does Creatine Boost Muscle Strength?
October 28, 2013 11:13 PM
How Does Creatine Boost Muscle Strength?
First of all what is Creatine? Creatine is a protein that is produced by the human body and converted to creatine phosphate and stored in muscles. The stored form can then be utilized for energy by the muscles. It is also found in meat and protein rich food products such as fish. Some clinical studies have surmised that creatine as an oral supplement enhance muscle strength and increase lean muscle bulk.
What Creatine Can Do?
Many young athletes utilize creatine supplements as part of their muscle building routines. Although there have been varied responses to these diet supplements creatine continues to thrive on the market as a sports and health vitamin. Other uses of it include lowering triglycerides in the body as well as homocysteine both of which play a role in heart attacks and strokes. Creatine also promotes better endurance and muscle strength among patients with chronic obstructive pulmonary disease, Parkinson's disease and Muscular Dystrophy. Clinical trials are still under way.
Creatine, like all other medications and supplements may cause some adverse effects. It is important that you consult a health Service provider or pharmacist before initiating the use of the supplement. The common side effects of Creatine include muscle cramps, weight gain, muscle strain, abdominal discomfort, changes in bowel movements, dizziness as well as liver and kidney dysfunction. This is due to the fact that this protein is metabolized in the liver and the kidney.
Creatine should be taken in the recommended dose. Taking more than the recommended dosage can result to severe adverse events such as Rhabdomyolysis which is the medical term for the breakdown of muscles, the components released after massive muscle cell death can damage the kidney and lead to kidney failure. The recommended dose for adults is 2g daily. Using creatine for prolonged periods may eventually lower your body's production of creatine and may lessen its effects.
When used judiciously and properly you can benefit from the positive effects of Creatine.
What is Monk Fruit And Why Is It Healthy?
July 24, 2013 10:24 AM
Monk fruit also known as luo han guo is a green melon cultivated in central Asia. It has been cultivated for many years by the Buddhist monks. The fruit contains an intensely sweet compound known as mogroside. It is a healthy, natural alternative to sugars and artificial sweeteners. The fruit is extracted in order to get mogroside which is many times sweeter than sugar. Monk fruit is crushed, combined with water, filtered and spray-dried to produce a sweet-zero-calorie powder known as fruit-sweetness. This sugar is used in several foods and beverages.
Ancient Chinese and Buddhist used monk fruit as treatment for various ailments, such as constipation, sunstroke and coughing. Modern research shows that mogroside can be used to treat diabetes since it contains a low glycemic index and can stimulate insulin secretion. In china, monk fruit was also used for many years to treat obesity and diabetes. The fruit contains antioxidants with anti- inflammatory benefits.
British Journal of Nutrition reported that use of monk fruit by animals showed a reduction in lipid peroxidation or cell damage as well as urinary albumin levels. This shows that it protects kidneys from diabetic damage.
Monk fruit strengthens the immune system, digestive tract, respiratory system as well as glands. This fruit is capable of eliminating and defending people against various health-related issues. The fruit reduces cholesterol, triglycerides and improve liver function. Furthermore, it increases good cholesterol while protecting the liver. It prevents cholesterol oxidization (due to its antioxidant potential) this results to reduced risk of heart diseases and strokes.Monk fruit extract has an antihistamine effect. The extract tends to counter an allergic response by soothing the mast cells that produces chemicals such as histamine. This chemical is related to both allergies and asthma. It is considered one of the best non-sugar sweeteners. It is combined with supplements used to promote and maintain a healthy weight.
Now foods and GMP Practices
February 04, 2010 12:36 PM
Author: Michael Lelah, Ph.D, Technical Directory, Now Foods
It should come as no surprise that 2009 was a challenging year with regard to the timeliness of order delivery, not just at NOW, but on an industry-wide scale. Many of the brands you carry have not been able to meet your demands.
In 2009 all medium-sized dietary supplement manufacturers, including NOW Foods, were officially required to meet the FDA's new dietary supplement cGMPs (current good manufacturing practices). NOW has placed very high quality standards on our products, and has been certified by NPA's stringent GMPs since 2000. Now that the FDA has started auditing manufacturers in our industry, we have found that the FDA requirements for the cGMPs are more strict than the early interpretations of experts.
This has resulted in ourselves and our industry being less prepared than anticipated, affecting the order fulfillment rates of many companies. We are actively working to respond to this.
Let's review the new FDA cGMPs. Good Manufacturing Practices, or GMPs, are manufacturing control systems designed to ensure that health products are manufactured in a consistent and safe manner. Standard operating procedures, specifications for all ingredients and products, and lab testing are cornerstones of GMPs. The FDA cGMPs are considerably rigorous, and by the FDA's own estimates, 25% of the brands you carry could be out of business as a result of not being able to meet their new cGMPs. Moreover, even for reputable brands, there is a lack of clarity on what the FDA expects, as much of this is new.
You might be wondering what all of this has to do with your orders? We at NOW Foods, along with other reputable manufacturers have increased our quality control efforts to meet the new FDA cGMPs. There are more requirements for ingredients and finished products, more documentation and more testing. The breadth of NOW's product line requires testing of thousands of ingredients. Based on the extensive nature of these efforts, coupled with disruptions in the supply chain, your orders have most likely been affected.
We are now better prepared to serve you. We are taking the safety of our products to entirely new levels and doing everything in our power to expedite the delivery of NOW products to your door.
Here are just a few examples of what we're doing:
Here's what you can expect from NOW Foods in 2010:
At NOW Foods we are continuing to work hard to meet your needs, despite the increased challenges to our supply chain. We hope and anticipate that as we move into 2010, you will reap the benefits of our quality and fulfillment efforts.
September 21, 2009 11:12 AM
Horehound has been around for thousands of years. The Romans used this herb in a combination as an antidote for poison. The horehound plant is a bushy plant that produces numerous annual branching stems. The plant is a foot or more in height and has whitish flowers. The leaves are much wrinkled, opposite, petiolate, and about an inch long. They are covered with white, felted hairs that give them a wooly appearance. The leaves have a strange, musky smell that can be diminished by drying the plant. Horehound is known to flower between June and September.
An ancient Greek physician by the name of Galen first recommended horehound for use in treating respiratory conditions. Early European physicians also used horehound to treat respiratory ailments. Early settlers in North America brought horehound with them to treat coughs, colds, and tuberculosis. The herb was also used to treat hepatitis, malaria, and intestinal worms. Horehound was also used to promote menstruation and sweating. Most commonly, the herb is used to treat colds and coughs, to soothe the throat and loosen mucus in the chest. Horehound is a well-known lung and throat remedy.
Warm infusions of horehound are able to relieve congestion and hyperemic conditions of the lungs. They do this by promoting an outward flow of blood. In large doses, horehound will work as a mild laxative. Applying the dried herb topically is a great way to treat herpes simplex, eruptions, eczema, and shingles.
The Romans praised horehound because of its medicinal purposes. Its Latin name Marrubium is derived from the word Maria urbs, which is an ancient town of Italy. The plant was called the ‘Seed of Horus” or the ‘Bull’s Blood,’ and the ‘Eye of the Star’ by the Egyptian Priests. Horehound was a main ingredient in Caesar’s antidote for vegetable poisons. It was recommended, in addition to its uses in coughs and colds, for those that had drunk poison or had been bitten by serpents. Horehound was once thought of as an anti-magical herb. Additionally, horehound is a Serviceable remedy against cankerworm in trees. Some believed that if it is put into new milk and set in a place where there are a lot of flies, it will quickly kill all of them.
The marrubiin content of horehound is believed to be the responsible component, giving it its ability to stimulate bronchial mucosa secretions. This information was obtained by German research done in 1959. Horehound can be used as a safe and effective expectorant.
The entire horehound plant should be used to provide alterative, anti-inflammatory, antitussive, aromatic, bitter, diaphoretic, diuretic, expectorant, mild purgative, stimulant, and stomachic properties. The primary nutrients found in this herb are iron, potassium, sulfur, and vitamins A, B-complex, C, E, and F. Primarily, horehound is extremely helpful in dealing with asthma, colds, coughs, croup, lung ailments, excessive mucus, phlegm, and respiratory problems.
Additionally, this herb is beneficial in treating bronchitis, infectious diseases, earaches, external eczema, fevers, glandular problems, jaundice, absent menstruation, and external shingles. For more information on the many beneficial effects provided by horehound, please feel free to contact a representative from your local health food store.
October 30, 2008 01:39 PM
National press has recently taken an interest in the benefits of folic acid, with coverage increasing throughout the media. Folic acid, a B vitamin and other folates helps the body to form red blood cells and aids in the formation of genetic material within every body cell. Folic acid also helps to prevent birth defects. Proponents of dietary supplements have encouraged the use of folic acid by women who are of the child-bearing age for a long time.
The public is becoming increasingly aware of the importance of this nutrient to prenatal development. In a survey done by U.S. Health and Human Services in 2007, about 40% of all women surveyed reported the daily consumption of a supplement that contained folic acid, while about 42% of women surveyed reported that folic acid is the most important vitamin for women of child-bearing age. This study also found that awareness of the benefits differed by age group. Younger women were the least likely to know about the benefits of folic acid, and therefore, were the least likely to consume folic acid. These younger women were also more likely to hear about folic acid from a magazine or newspaper or school or college, rather than their health-care provider.
On the contrary, the women who aged 25-34 and 35-47 were much more likely to hear about folic acid and its benefits from their health-care provider. Because of these results, the U.S. Health and Human Services considers it vital to increase young person education and awareness. Folic acid has long been known to help prevent birth defects. Recent research on folic acid shows that it may also help in preventing premature births, boost baby weights, prevent preeclampsia, reduce risk of Alzheimer’s disease, and even cut male smokers’ stroke risk.
Folate is determined from the term “foliage,” and is a member of the B vitamin family where it can be primarily found in dark leafy green vegetables, legumes, citrus fruits, beets, meat, and wheat germ. Folic acid does not occur in nature and cannot be found in unfortified foods. It is not an active form of the B-vitamin. However, it is the most common form of folate used is supplements and in fortified food products due to the fact that it is highly bioavailable and chemically stable. It is also readily reduced to tetrahydrofolate, which is the active coenzyme form of folate. One study, comparing folic acid from orange juice and folic acid from a supplement showed that the supplement had a better absorption rate than the fortified orange juice.
Although folic acid is not generally associated with side effects, there have been some clinical reports that high level of folic acid can mask a deficiency of vitamin B-12. However, a deficiency of B-12 is very uncommon and it has been determined that only amounts about 3000 – 4000 micrograms per day of folic acid for extended periods of time may have this masking effect, which can in turn be eliminated by supplementing with a few micrograms of B-12. For more information about folic acid and its benefits to your body, contact your local health food retailer.
Activated Charcoal - Highly absorbent material to combat poisoning
April 24, 2008 02:44 PM
Activated charcoal has been treated by heat to open up millions of small spaces between the carbon atoms and turn it literally into an atomic sponge that adsorbs both organic and organic impurities.
This heat treatment is carried out in the absence of oxygen, so the charcoal cannot burn. Instead, what oxygen it did contain is driven off leaving behind all of these interstitial gaps that multiply the effective surface area by factors of ten. Since it is the surface area of the charcoal that determines its potency, then the greater this is the better.
Activated charcoal has a massive surface area, and just ten grams has the same surface area as nine American football pitches or 77 tennis courts. Ten grams is just marginally more than a third of an ounce. The term adsorb has a different meaning to absorb, and while a real sponge absorbs water by mopping it up through capillary action and suction, activation carbon adsorbs substances through a form of chemical attraction. You get rid of water from the sponge by squeezing it, but that doesn’t work with activated charcoal, since the substances are bound to it, not just physically constrained.
This huge surface area provides activated charcoal with innumerable bonding sites, and when chemicals that are attracted to carbon pass by they are attached to the surface. They cannot get free again, as water in a sponge can, but are bound to the surface of the carbon. Because the digestive system has no effect on charcoal then whatever is bound to it passes naturally through the body.
It is most effective at binding other carbon-based materials, and other substances with the right electronic arrangement, but others will just pass straight through. Because it is a chemical process, once all of the empty bonding sites have been taken up, the charcoal loses its effectiveness and has to be replaced. It is possible to regenerate it, but hardly worthwhile for you to do so because of the small quantities you use.
Because of the way it works, activated charcoal can help people to recover from some forms of food poisoning. It can adsorb gases in the intestine and help to relieve the pain of excessive gas in the gut. It has many additional uses that will be touched on later, but for now we will look at its effect on poisons because that is where activated charcoal is of greatest benefit to us.
It does not adsorb and neutralize all poisons, but is very effective with those that it can be sued for. Professor Touery proved a point when he drank a lethal dose of strychnine in front of colleagues at the French Academy of Medicine in 1831 and came through unscathed. He had mixed the strychnine with activated charcoal, and the fact that he lived after drinking a dose that would certainly have led to a very painful death within minutes testifies to the powerful effect of activated charcoal as an potential antidote for poisoning.
Ever medicine cabinet should have an emergency supply of activated carbon, especially those with young children in the household. However, this is not good news for the pharmaceutical companies who have reacted by refuting some of the claims made in its favor: they have claimed that it is not effective against arsenic. If that is so, then how did Michel Bertrand survive after swallowing 5 grams of arsenic trioxide – 150 times what is regarded as the lethal dose? He did this is 1813 after mixing it with activated charcoal, just as Professor Touery was to do 18 years later with ten times the lethal dose of strychnine.
It is true, however, that it does not have this degree of activity with all poisons, and it has no effect on cyanide, alcohols, antifreeze (glycols) and lithium. It also has no effect on corrosive poisons such as the strong alkalis used in oven clearers, or hydrocarbons such as kerosene. The way it works is adsorb the poison and prevent it being released into the body. For that to happen, the poison must have an affinity for carbon, and its adsorption site, and not all substances possess that property. Those that do however are permanently bound and therefore safe.
For charcoal to be effective in neutralizing a poison, it must be swallowed within an hour of taking the poison, or the poison will be too far advanced ion the digestive process for the charcoal to do any good. Keep in mind, though, that it is not selective, and activated charcoal can adsorb nutrients and other beneficial constituents of your body’s chemistry. It is important therefore that you take in only when necessary: you might need several doses if the poison was severe, but once it has done its job it is not meant to be used as a maintenance material to take ‘just in case’. Used like that, it can do harm.
If charcoal can adsorb poisons then it makes sense to believe that it can also adsorb some of the harmful agents that cause food poisoning. Not all food poisoning of course, but certainly those organisms that emit toxins that are attracted to carbon. And this is, in fact, the case. Food poisoning is caused by bacteria rather than viruses, and is not the presence of the bacteria that make you vomit and feel very ill.
As bacteria grow in your body they release toxins, or poisons, into your digestive system. These poisons are what make you ill. They can seriously affect the complete gastro-intestinal tract, causing vomiting, diarrhea, and inflammation and swelling of the small and large intestine. The latter can cause abdominal cramps and severe colic, and the severity of the symptoms depends very much upon the type of bacteria and the number of them in your body.
Many of these toxins are attracted to carbon since they are frequently organic based, and activated charcoal can be used to adsorb them. Once adsorbed they lose their potency, and since carbon is not digested by the body, they are passed harmlessly through the colon and eliminated in the faeces. It can also be used to eliminate many other foreign bodies from your gut, including viruses and fungi and might possibly reduce the concentration of uric acid, which can bring relief to gout sufferers.
Activated charcoal has many uses, and is normally available in capsule form. It can be dangerous to take too much, particularly if you suffer from intestinal problems that cause constipation, because the charcoal itself can have that effect. However, there is no better emergency treatment for accidental poisoning in the home, although, since it is not suitable for all poisons, you must still regard poisoning as an emergency and contact the emergency Services.
Activated charcoal, or activated carbon as it is sometimes called, is also a good emergency treatment for vomiting and the other unpleasant effects of food poisoning. It deals with bacterial toxins in the same way as any other, though once again you must refer to your physician before or after using it – preferably the former.
May 28, 2007 11:33 AM
Humankind has long searched for a special elixir that would confer immortality…or, failing that, at least prolong youthful vitality for a decent number of years. Resveratrol is no magic potion, but it has improved survival rates among mice at the ripe old age (for a mouse) of 114 weeks even overweight mice fed high-calorie chow (Nature online 11/1/06). What’s more the Resveratrol bolstered rodents stayed fit and trim well into their senior years; as Dr. Rafael de Cabo of the National Institute on Aging told the news Service heartwire, such a finding “suggests that this compound may not just extend life but may also enable individuals to lead healthy and functional lives for longer.”
While tests continue on how Resveratrol could produce these results, it is believed that this substance may actually mimic the effects of calories restriction, which has been shown to increase longevity. Resveratrol apparently activates a gene known as SIRT1 activation is also associated with greater exercise capacity and fat burning.) in addition, Resveratrol both acts as an antioxidant itself by mopping up dangerous molecules called free radicals and helps enhance the antioxidant effects of vitamin C and E.
Barking Up The Wrong Tree – Dietary Supplements are targeted while foods sicken millions.
November 09, 2006 11:54 AM
The FDA and our enemies in Congress want you to believe that non-causal Adverse Event Reporting (AER, as presented in the S.3546 bill in Senate and the HR.6168 now in the House of Representatives) for supplements should be implemented to protect our health. The latest nationwide E.coli outbreak casts a shadow of doubt on S.3546/HR.6168 supporters’ motives, however-because these bills are treating safe, natural supplements as dangerous threats while foods wreak havoc on our nation’s health.
By the time this issue went to press, 187 people had been sickened and as many as three people had died from toxic E.coli bacteria found in contaminated bags of spinach. Tragically, this is nothing new; the Centers for Disease Control and Prevention estimate that food borne disease cause approximately 76 million illnesses, 325,000 hospitalizations and 5,000 deaths in the United Stages each year. More than 200 known diseases are transmitted through bad food.
Despite these staggering figures, there is no adverse event reporting system in place for foods. So if our enemies in Congress truly want to protect us, why are they pursuing non causal AER for safe, natural dietary supplements and not foods? The unfortunate answer is that non-causal AER supporters are either ignorant or in pursuit to non-disclosed political agendas. The latter is extremely disturbing especially when these self serving political agendas, promoted in the name of “protecting health,” will actually harm public health by taking away our supplements.
Not only are AER supporters barking up the wrong tree, but the AER bills that they have constructed are totally destructive. S.3546/HR.6168 is based on association and not causation. That’s right—S.3546/HR.6168 disregard what actually caused an adverse event, and instead use “guilt by association.” These poorly constructed bills are impotent when it comes to protecting people, but nonetheless are poised to devastate the nutritional supplements industry. If passed, S.3546/HR.6168 will unleash a barrage of frivolous lawsuits that will make trial lawyers rich while bankrupting the entire nutritional supplement industry and taking away our vitamins forever.
It is hard to imagine why some elected officials, the FDA and certain nutritional supplement industry groups are channeling so much money and energy into AER for harmless supplements while potentially deadly pathogens are tainting our food supply and sickening millions. If our elected officials truly wish to help the American people and protect public health, they should leave safe, natural dietary supplements alone and focus their AER efforts on foods—but only if they take the time to draft an intelligent, functional AER bill that is based causality.
Don’t Give Up the Fight
Adverse events with supplements are practically nonexistent. Adverse events with food are abundant. Elected officials who support S.3546/HR.6168 and the non-causal AER they espouse are clearly misguided, with an imbecile’s grasp on prioritization. If you agree that non-causal AER for supplements is an unwarranted waste of time and will destroy the industry by guilt by association, then please voice your opinion, before it’s too late!
Please call and fax Joe Barton, Chairman of the Committee on Energy and Commerce, and other key AER players at the following numbers (fax numbers second): Barton at 202-225-2002, 202-225-3052; Chairman of the Judiciary Committee F. James Sensenbrenner, Jr. at 202-225-5101,202-225-3190; House Majority Leader John Boehner at 202-225-6205, 202-225-0704; Speaker of the House J. Dennis Hastert at 202-225-2976,202-225-0697; and Congressman Nathan Deal a member of the Energy and Commerce Committee, at 202-225-5211, 202-225-8272.
Don’t let self-serving political skullduggery take your vitamins and supplements away from you! Visit www.NHA2006.com and take advantage of online tools that allow you to easily send faxes to Congress. Please do not delay—without swift and decisive action, we may all lose our health freedom forever!
*This editorial is a public Service announcement sponsored by the Nutritional Health Alliance (NHA).
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
May 30, 2006 02:36 PM
Ambassador to Health Profile
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
Congressman Sam Farr, a fifth-generation Californian, represents the state’s beautiful central coast. His district encompasses the length of the big Sur coastline in Monterey County, the Monterey Bay National Marine Sanctuary, the Salinas Valley “Salad bowl,” the redwoods, mountains and beaches of Santa Cruz County, and the majestic rural landscape of San Benito County. The health and wealth of this region has been strengthened by Rep. Farr’s focus on the environment, education and the economy. Rep. Farr was raised in Carmel, California and graduated from Willamette University with a BS in biology. He later attended the Monterey Institute of International Studies and the University of Santa Clara. He is fluent in Spanish. As a tough advocate for the health food industry, he has lobbied for strict federal organic standards.
Todd: Congressman Farr, thank you for taking the time to speak with us! Id also like to thank you for all the great things you’ve done for our community, form funding marine sanctuaries and authoring the Ocean’s Act to expanding Pinnacles national Monument. The League of Conservation Voters and others have recognized you as an “Environmental Hero”. And, you’ve worked hard to support the economic vitality of central coast’s $3 billion agriculture industry which includes a substantial organic segment. Our backyard here is also the home of a robust group of nutritional supplement manufacturers. An estimated 187 million Americans are currently taking dietary supplements as part of their daily healthy diet. In California, we’ve got 792 natural product manufacturers and distributors. Where do you stand on the state of our industry?
Congressman Farr: Well, thank you for the introduction and for asking to talk to me about nutritional supplement issues. I am very supportive of this industry and include myself in the 187 million Americans taking dietary supplements. I think supplements offer many safe and viable tools to maintain your health. The continued growth of this industry is an indication of both consumer confidence in the products and the products’ ability to fill the gaps where conventional medical care falls short.
Todd: It is estimated that by 2030, more than 70 million Americans will be over the age of 65 and the cost of health care could reach $16 Trillion per year. A recent study by the Lewin Group showed that by taking certain dietary supplements, seniors can lead healthier, more productive, independent lives while saving billions in reduced hospitalizations and physician Services. Do you share our view that a Wellness Revolution is needed to counter the dilemma of an aging population versus shrinking health care support in the future?
Congressman Farr: Our health care system is definitely facing a challenge, especially as the Baby Boomers hit their 60’s and Americans are living longer than ever before. As a Baby Boomer myself, I am well aware of America’s aging population and the impact that will likely have not only on our social institutions but also our fiscal well-being. I agree that dietary supplements do play and will play an even larger role in the future as more seniors look for a way to augment their diets in order to stay healthy and active longer than past generations.
Todd: Our industry is regulated by DSHEA (the Dietary Supplement Health and Education Act), which was passed unanimously by Congress in 1994 to create a reasonable regulatory framework for access to, information about, dietary supplements. But many say that the FDA and DSHEA weren’t adequately funded to do the job as tasked. “Supplements are unregulated” is a false argument we sometimes hear. To ensure that the FDA is able to carry out the law as Congress intended, Representatives Dan Burton (R-Ind.) and Frank Pallone (D-N.J.) introduced H.R. 2485, the DSHEA Full Implementation and Enforcement Act of 2005. Did you support this bill and where does it stand today?
Congressman Farr: I think the DSHEA is a critical law and was proud to support it when Congress considered it in 1993 and 1994. I would certainly support H.R. 2485 if it came up for a vote in Congress. Unfortunately this bill has not moved since it was first introduced and referred to the Subcommittee on health in the house energy and commerce committee. Since this is an election year we have a tight schedule with only about 60 legislative days scheduled before we adjourn. That means it’s likely Congress will only finalize bills such as the appropriation bills that fund government before adjournment.
Todd: Our business climate has included some valid and rigorous challenges to improve our industry, from good manufacturing practices (GMP), to allergy labeling, to implications of Prop-65 in California. It’s disconcerting that a new bill, H.R. 3156 The Dietary Supplement Access and Awareness Act would try to capitalize on misconceptions about the industry. In an era of declining health care and declining insurance coverage, this bill would regulate supplements as prescription drugs. Among other things, it would also require adverse event reports to be turned over to the FDA, even though other foods, including those with identical ingredients, do not have the same requirements. This has the potential to be the next Prop-65-like Lawsuit mill. The result of H.R. 3156 would be chilling. It will knock smaller producers out of the market. It will result in higher prices for all supplements. It will decrease the availability of health-giving supplements to the public. What’s your feeling on this?
Congressman Farr: I am similarly concerned about H.R. 3156 and would oppose it if it came up for a vote in Congress. Like H.R. 2485, this legislation has been referred to a subcommittee on Health in the House Energy and Commerce Committee without any further action. The supplement industry has worked in good faith with the FDA since passage of DSHEA and H.R. 3156 would re-invent a wheel that isn’t needed. Instead, adequate funding as proposed in H.R. 2485 would provide ample oversight for the industry.
Todd: According to a recent study, 72% of the general population believe the government should fund more research on health benefits of nutritional supplements. Do you agreen and what can be done to meet this need?
Congressman Farr: I definitely agree that the federal government should play a bigger role in support of research regarding the health benefits of nutritional supplements. As a member of the House Appropriation Committee, I sit on the subcommittee that has jurisdiction over the FDA’s budget and I know the tight fiscal restraints the agency is under. I’ve worked with my colleagues to provide adequate funding, but it’s an uphill battle especially when we’re in a “robbing Peter to pay Paul” kind of situation. I recommend that people within the industry organize and use your consumer base to actively lobby Congress for additional funds. I’m fond of reminding people that the squeaky wheel gets grease – so let every Congress member and Senator know how much this issue matters to you.
Todd: When there is overwhelming scientific evidence that nutritional supplements provides relief for a disease condition, it currently takes a lawsuit to get the FDA to relent and allow the claim. Even then, the FDA strictly limits the claim and requires a disclaimer that does more harm than good in communicating this important information to the public. There is a new bill, H.R. 4282, The Health Freedom Protection Act that would end FDA and FTC censorship of health information. As an example, the 50% of all adult males who suffer from an enlarged prostate could receive relief from that condition by consuming a simple and safe ingredient, saw palmetto derived from the fruit of the dwarf American palm tree. The FDA censors that information. The public deserves a better opportunity to be informed about omega-3 EFA and heart disease, folic acid and birth defects, phosphatidylserine and cognitive impairment. Do you agree and do you support this bill?
Congressman Farr: I agree the public needs to access to the best information possible so they can make well informed choices about their health. I likely would support H.R. 4282 if it came up for a vote in Congress. Unfortunately this bill is in a similar situation as other we’ve mentioned in this interview – and again because of the tight schedule of an election year, it’s unlikely action will happen this year.
Todd: According to the barometer study, 85% of the US population is currently using some type of dietary supplement. Do you? Looking at your busy schedule from co-chairing the House Oceans Caucus to your seat on the Travel and Tourism Caucus, you are one busy congressman! Are you popping nutritional supplements please tell us!
Congressman Farr: I do take some nutritional supplements, though they vary and since Ginkgo Biloba isn’t among them I cant remember their names off-hand! One product I do use faithfully is Airborne to help me combat germs and colds that I might get from sitting on an airplane. But, like many Americans my life is over-scheduled and combined with the amount of air-travel I do, I find nutritional supplements helpful as I try to stay healthy despite my hectic lifestyle.
Todd: Thank you Congressman Farr! Live long and prosper!
DSEA Release of Health/Cost Impact Study Conducted by the Lewin Group, Initial Results, Wash DC; Nov. 2, 2005
NNFA database. Adam.F on 3-15-06.
DSEA Nutritional Supplement Barometer Study, 2005 Report, Prepared by the Natural Marketing Institute (NMI).
Todd Williams; Source Naturals Marketing Programs Manager.
March 27, 2006 06:23 PM
Now Foods Vitamins Discount Prices
If there’s one truth to be told about the natural products industry, it is this. We will never have a shortage of companies claiming to be the best. It happens so often in fact, that distinguishing the quality from the questionable has become an exhausting task all in itself. After all, making claims is easy. What’s challenging, however, is supporting these claims with something concrete.
As no stranger to recognition, NOW takes pride in every honor that is bestowed upon us. And yes, over the past year, we have been blessed in many ways. Nothing, however, can match the sense of reward that comes from having our efforts, values and commitment to human wellness acknowledged by our peers, colleagues and valued customers. It is with the most sincere gratitude that we are once again able to share these with you.
Vitamin Retailer Magazine’s 2005 Vity Awards Every Spring, Vitamin Retailer Magazine recognizes the most outstanding dietary supplements, and honors the recipients with a Vity Award. The winning products are selected based on a number of criteria. This year, three NOW products were awarded 1st place honors.
The first was presented in recognition of our MSM 1000 mg. This marks the third consecutive year that we’ve watched our MSM excel in this category. Next was the award for Vitamin E, which went to our Natural Vitamin E-400 mixed tocopherol formula. Like MSM, this was also awarded 1st place st place for the third year in a row. Finally, the award for “Best Calcium”, which was given to our Calcium Citrate. With the calcium category regarded as one of the most competitive, taking top honors is an accomplishment that we’re all very proud of. Whole Foods Magazine Natural Choice Winner Best Sports Supplement
It should come as no surprise to anyone that there are literally hundreds of protein formulas available. When it was announced that our line of Whey proteins had earned the title of “Best Sports Supplement” from Whole Foods Magazine, we were truly honored to be selected as one of their Natural Choice winners.
Each year, Whole Foods Magazine evaluates hundreds of products, selecting only those that meet their demanding standards. Our Sports division has worked tirelessly to perfect our Whey proteins, and this award is a true testament to the efforts they have put forth. NOW is one of the very few companies that offers a line of 100% natural proteins, free of artifi cial sweeteners. Accordingly, this is an honor that we’re especially proud of. Nutrition Business Journal’s Lifetime Leadership Award, Elwood Richard
Nutrition Business Journal recently honored NOW founder Elwood Richard, with their prestigious Lifetime Leadership Award. Mr. Richard has been an active member of the natural products business since 1960 and is a strong advocate for both science and quality. He co-founded the NNFA standards committee, and sponsors industry organizations such as Citizens for Health, NNFA, ABC, AOAC and AHPA among others. His hard work, vision and commitment have inspired our entire organization
in supporting independent retailers, producing quality products and taking proactive measures towards environmental preservation.
Nutrition Business Journal’s Business Achievement Award, Environment of Sustainability In addition to the award presented to Elwood Richard, NOW was also the recipient of the NBJ Business Achievement Award for Environment of Sustainability. This honor is presented to businesses who have consistently participated in both internal and local initiatives to make positive environmental impacts. Notably, our recycling program has reduced waste output by over 50%. NOW FOODS Vitamins also conducts employee training programs, supports community conservation efforts and hosts volunteer workdays to plant vegetation, remove litter and control lakeside erosion in a local forest preserve. These actions have earned us a number of community Service awards from several local recreation organizations. Finally, we help support environmental organizations, including The Nature Conservancy and World Wildlife Fund.
AOAC adopts NOW Glucosamine Method
NOW Foods’ glucosamine HPLC method has passed the AOAC’s 2-year validation process to become the fi rst offi cial method for testing the standards of this popular joint health ingredient. It was selected by the expert review panel in April of 2003 as the “best method for further laboratory validation”. It will be published in the Journal of AOAC International and become available to the industry this summer, 2005. “Having NOW’s method for glucosamine become the offi cial AOAC method is a testament to the expertise of our staff, our focus on the science, and our commitment to quality,” said Michael Lelah, technical director of NOW Foods.
DuPage County Forest Preserve District’s Shooting Star Award.
The DuPage County Forest Preserve District of Illinois recently presented NOW Foods their Shooting Star Award at their annual Forest Preserve District volunteer banquet. This award recognizes the long-term efforts that our entire organization has made in order to improve and support the quality of the East Branch Forest Preserve in Glendale Heights, IL. This is also the fi rst time that the District has given this award to a company. As the primary recipient, we look forward to furthering our environmental efforts.
Recapping our 2004 Achievements
Eight 1st Place Vity Awards, from Vitamin Retailer Magazine
United States Department of Commerce Excellence in Export Achievement Award
Nutrition Business Journal’s Effort on Behalf of Industry Award Consumerlab.com Top Rated Brand in Health Food Stores based on Customer Satisfaction Natural Nutritional Foods Association (NNFA) Crusader Award, Elwood Richard Vitamin Retailer Magazine Manufacturer of the Year (2003)
Lutein to fight age-related macular degeneration!
February 27, 2006 05:53 PM
Lutein: The Antiordinary Antioxidant
Lutein belongs to a class of compounds known as carotenoids. Carotenoids in general are yellow, orange, or red pigments responsible for many of the colors of the foods we consume each day. To date, over 600 carotenoids have been identified in nature, but are only produced by plants, algae and bacteria leaving humans and animals to consume carotenoids in the diet. Forty to fifty carotenoids are consumed in the typical US diet, but only 14 have been detected in the blood, indicating a selective use of specific carotenoids by the body. Lutein is one of these carotenoids found in the blood and has been increasingly associated with eye health over the last decade.
Lutein’s role in eye health
In the human eye, lutein is concentrated in the center of the retina in an area known as the macula. Lutein is deposited in the macula through the lutein we consume in out diet or through supplements. This area is responsible for human central vision and is colored intensely yellow due to high concentrations of lutein. Lutein is thought to be beneficial for eye health by reducing damage in the eye in two ways: 1) by absorbing blue light (blue light is thought to increase free radical formation in the eye) and 2) by acting as an antioxidant, reducing damage in the eye caused by free radicals. Leading carotenoid researchers believe these functions may lead to a reduced risk of age-related macular degeneration (AMD) and cataracts.
Age-related macular degeneration
Macular degeneration is the leading cause of blindness in the USA in those over 65. twenty-five and thirty million people are afflicted worldwide and currently there are no effective treatments for the disease. The disease has two forms known as dry and wet AMD.
Ninety percent of AMD cases diagnosed are the dry form. In dry AMD, also referred to as early AMD, debris deposits under the center of the retina (known as the macula) interfering with its normal function. Parts of the macula atrophy, causing the central vision to slowly become dimmer or more blurry. Wet age-related macular degeneration, also known as late AMD, often develops in areas where dry AMD exists. Abnormal blood vessels grow and leak blood and fluid under the macula, causing scarring, which leads to rapid loss of central vision.
Dr. Joanna Seddon published one of the first studies demonstrating a link between lutein intake and AMD risk in 1994 (1). This epidemiological study compared the risk of developing AMD to nutrient intake and showed a significant reduction in risk for developing AMD as lutein intake reached 6mg per day (57% reduction in risk). Since the Seddon study, researchers have shown that increasing dietary lutein intake raises blood levels of lutein as well as levels of lutein in the eye (2). Bone et al. demonstrated that eyes with higher levels of lutein were less likely to be afflicted with AMD (3).
The latest clinical trial that investigated lutein’s role in AMD is known as the lutein antioxidant supplementation trial (L.A.S.T) (4). This study evaluated the effects of lutein supplementation for one year in 90 veterans diagnosed with dry AMD. Supplementation with lutein in these subjects significantly increased the concentration of lutein in the macula. Improvements in visual function were also detected with lutein supplementation. Glare recovery, visual acuity, and contrast sensitivity were all improved. This study continues to build on clinical evidence that the dry form of AMD may be responsive to changes in nutrition.
A cataract is a natural clouding of the lens, the area of the eye responsible for focusing light and producing clear, sharp images. For most people, cataracts are a natural result of aging. Currently in the US, cataracts are the second leading cause of blindness in the elderly behind AMD.
Lutein is the major carotenoid that has been identified in the human lens asn is thought to provide similar benefits to the leans that are seen in the retina. Two large epidemiological studies consisting of >70,000 women (age 45-71) and >30,000 men (age 45-75) compared the risk of cataract extraction to nutrient intake (5,6). Similar to AMD, a significant reduction in risk of cataract extraction was associated with lutein intakes of 6mg per day (20% reduction in risk). Besides cataract extraction, higher levels of lutein consumption have been associated with a decreased risk of cataract development and improvements in visual acuity and glare sensitivity in people with age-related cataracts.
The richest source of free lutein in the typical US diet are dark green leafy vegetables, with the highest concentration found in kale followed by spinach.
The average daily lutein intake is low, average between 1-2 mg/day. Currently there is no recommendations of the dietary guidelines for Americans 2005 (9 servings of fruits and vegetables every day) you would consume between 4 and 8 mg of lutein a day (7). Epidemiological evidence, animal models, and clinical data have indicated levels of 6-10 mg a day may be necessary to realize the health benefits associated with lutein consumption. By continuing to increase our intake of lutein, we begin to ensure the optimal health of our eyes.
Seddon et al. (1994) dietary carotenoids, vitamin a, c, and e, and advanced age-related macular degeneration. Eye disease case-control study group. JAMA. 272: 1413-20.
Bone et al. (2000) Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Exp. Eye Res. 71: 239-45.
Bone et al. (2001) Macular pigment in donor eyes with and without AMD: a case-control study. Invest. Ophthalmal. Vis Sci. 42: 235-40.
Richer et al. (2004) Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-relaged macular degeneration: the veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 75: 216-30.
Brown et al. (1999) A prospective study of carotenoid intake and risk of cataract extraction in the US men. Am. J. Clin. Nutr. 70: 517-24.
Chasen-Taber et al. (1999) A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am. J. Clin. Nutr. 70: 509-16
HHS/USDA. Dietary Guidelines for Americans 2005. //www.healthierus.Gov/dietaryguidelines/CDC. National health and nutrition examination survey data 2001-2002. //www.cdc.gov/nchs/about/major/nhanes/nhanes01-02.html
Brandon lewis, Ph.D. is the applied research and Technical Services manager at kemin health, L.C. in des moines, iowa. His responsibilities include the initiation and management of laboratory projects pertaining to the inclusion and analysis of kemin ingredients in vitamins and dietary supplements, as well as developing new applications and prototypes that include kemin ingredients. Prior to joining kemin, Brandon was enrolled at the university of Florida where he received his Ph.D. in Nutritional Science from the department of Food Science and Human Nutrition.
Acai is an exotic palm fruit from the Amazonian rain forest!
February 12, 2006 01:38 PM
Vitaberry Plus + Super Fruit Antioxidant
December 07, 2005 05:43 PM
Vitaberry Plus +™ Super Fruit AntioxidantBy Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and Services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),
- Catalase (neutralizes peroxides),
- Functions similar to reduced Glutathione (GSH),
- Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent),
- Functions similar to Glutathione S-transferase (GST),
- Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
NOW is the leader in quality and value
October 21, 2005 08:12 AM
NOW is the leader in quality and value
“We only deal with companies that support the natural products industry and have a strong public Service mission”
We couldn’t agree more. NOW has, and will continue to fight for the rights of consumers to take safe supplements. As one of the most active and influential advocates in the natural products industry, we proudly support the following industry organizations.
NFA, Citizens for health, AHPA, OTA, The Herb Research Foundation, The American Botanical Council, Consumers for Health Choice (UK), The GMO Task Force, The GMP Task Force, American Herbal Pharmacopoeia, The Campaign to label Genetically Engineered Foods, AOAC (method validation), AOCS (American Oil Chemist Society), The Dietary Supplement Education Alliance (DSEA), and More…
“Does NOW support any Charitable or public Services?”
NOW is a leading recycling company and was awarded a silver medal for nutrition business journal in 2005 for our dedication to environmental and sustainability issues. We use environmental-friendly packaging and procedures to ensure that our impact on the environment is minimal. Here are just a few of the charities and originations NOW generously supports:
Local Heal Clinics and food banks, Salvation Army, Marklund children’s home, African meal-a-day fund, compassion international, vitamin angel, world relief, Indian orphanage, Hephzibah children’s home, nature conservancy, Americas second harvest, world wild life, and many more
Adverse Reactions to Foods and Dietary Supplements
August 27, 2005 08:27 AM
Adverse Reactions to Foods and Dietary Supplements
Answers to common Questions
The Journal of the American Medical Association reports that between 60,000 and 106,000 deaths per year in the United States are caused by prescription drugs. See JAMA, April 15, 1998 – Vol 279, No. 15. Fortunately, adverse reactions to foods and dietary supplements are far more rare than adverse reactions to drugs. However, we each consume a larger variety and quantity of foods than drugs. Because of this, and because each of us can react differently, an allergic or isolated reaction to a food or supplement is a possibility. Here’s helpful information about what to do if you or someone you care for has what appears to be an adverse reaction to a food or dietary supplement.
What types of reactions could I have?
The most common adverse reaction is an allergic reaction. In order to reduce the risk of an allergic reaction, carefully read all labels and buy products from reputable manufacturers who accurately disclose the ingredients in their products. If you need help finding these manufacturers, ask your local health food retailer for recommendations.
How do I know what caused my reaction?
Take time to carefully review what might have caused the reactions. Doctors and experts in toxicology look at several different factors in trying to determine the cause of a particular reaction.
1. Is this reaction a side effect of drugs I am taking?
Asking your self these questions can help limit the number of possible causes and may lead you to an answer more quickly.
What should I do if I have an adverse reaction?
Weather or not you know the potential cause of the reaction, follow these steps:
How can I reach the FDA or another government agency about my concerns?
Various state and federal agencies employ personnel who can help respond to concerns or questions about adverse reactions. Following is contact information for some of the agencies:
How can I report an adverse event?
FDA’s Center for Food Safety and Applied Nutrition (CFSAN) has an Adverse Event Reporting System (CAERS) that can be contacted in any of the following ways:
You can contact FDA’s MedWatch Program in any of the following ways:
For Non-emergencies related to products purchased via internet, fill out an online form on FDA’s website at vm.cfsan.fda.gov/~dms/qa-top.html (see link to “form to report unlawful sales”)
You may also contact any local poison control center, local or state health agencies, the department of Health and Human Services, the Federal Trake Commision, the Consumer Products safety Commission, or the Centers for Disease Control and Prevention, and t hey will forward your report to the FDA.
The benefits of a manual exam for prostate cancer far outweigh any embarrassment.
July 27, 2005 02:14 PM
2. The benefits of a manual exam for prostate cancer far outweigh any embarrassment.
While women routinely visit the GYN for yearly or even bi-yearly exams, many men find the idea of being examined so intimately to be disconcerting. “It’s not their favorite exam, but it’s not that painful,” admits Dr. E. Roy Berger, MD, FACP, Director of North Shore Prostate Cancer Consultation and Treatment Service at North Shore Hematology/Oncology Associates in East Setauket, New York. “There is no spectrum involved. It’s just a finger.” Education and understanding are the key to men overcoming their anxiety. It’s also an opportunity for women to reassure their significant others that this type of exam is vital to good health and a gratifying love life. “Patients should actually ask their primary care doctor for a digital rectal exam,” suggests Berger. “It’s a matter of mindset.”
Doctors Reject Dietary Supplement as Diabetes Treatment
July 27, 2005 10:27 AM
Doctors Reject Dietary Supplement as Diabetes Treatment
(2/23) SUZANNE LEIGH c.1999 Medical Tribune News Service
Doctors say they will not be recommending a drug that has been found to improve insulin resistance in type 2 diabetics.
In a study published in the current issue of the Journal of the American College of Nutrition, patients with type 2 diabetes had less insulin resistance after undergoing an infusion of the amino acid L-carnitine.
Oral and injectable forms of this amino acid _ which is produced naturally in the liver_ are already prescribed as the drug levocarnitine for patients with carnitine deficiency. The drug also is available as a dietary supplement. Makers claim it can enhance athletic performance and protect against liver, kidney and heart disease.
Unlike patients with type 1 diabetes, who do not produce insulin, patients with the type 2 variation may manufacture adequate levels of insulin but develop resistance to its effects. Insulin is essential for the transportation of blood sugar, or glucose, into cells so they can produce energy.
Dr. Geltrude Mingrone and colleagues from the Catholic University in Rome evaluated the effects of insulin and L-carnitine on 15 type 2 diabetics and 20 healthy volunteers.
Earlier studies cited in the report found that L-carnitine improved heart function in diabetics and increased the level of glucose oxidation, a process that helps cells make use of glucose. The researchers found that both the diabetic group and the healthy volunteers experienced an 8-percent increase in glucose use with L-carnitine compared with a placebo.
This 8-percent increase compares modestly with a previous study using a higher dose of L-carnitine that found glucose use was increased by 17 percent. Dr. Richard K. Bernstein, director of the New York Diabetes Center in Mamaroneck, said the study demonstrated benefits that were ``only slightly higher than marginal."
Bernstein said that he prescribed L-carnitine with some success to patients with poor circulation, but did not expect to recommend it for insulin resistance. ``If we were to see an increase of 50 percent in glucose utilization, then we might want to look at the study more closely,"
Doctors said they would continue to prescribe drugs like metformin and troglitazone for insulin resistance. Dr. David M. Nathan, director of the Diabetes Center and the General Clinical Research Center at Massachusetts General Hospital in Boston, said he was satisfied with the safety and effectiveness of both drugs provided the patient was monitored at regular intervals for kidney and liver function.
Women and vegetarian diets: care needed
July 27, 2005 09:54 AM
Nutritional trends have dictated especially to women to eat less meat and more vegetables and fruits. While only about one percent of North American men are vegetarians, it is estimated that four times this number of women do not eat meat. In addition, it is evident that even more women try to avoid dairy products (though in what proportion is not clear). While at first glance, this may seem good, nutrition surveys of vegetarian women have shown that they are deficient in some very essential nutrients. In fact, vegetarian women tend to have lower levels of calcium, iron, zinc, and vitamins D and B12. For women who eat some animal products, the levels of each of these nutrients increases. Of course, the highest levels of these nutrients are seen in women who do not restrict their diets to nonanimal foods. Calcium and iron are two of the nutrients most lacking in diets of both vegetarians and omnivores.
These results do not mean a vegetarian diet is unhealthy but that it needs better planning than most people give it. It also indicates that women at risk for deficiencies of the nutrients listed above are not getting them from diet or supplements. In fact, most women (and men, for that matter) have individual dietary needs that can only be determined by that individual.
If you follow a special diet, keeping a diet diary for a week and then analyzing it for the nutrients listed above will give an indication about its nutritional adequacy. (But only an indication since all nutrients should be supplied by the diet.) This type of Service is usually available from a Registered Dietitian, but you can do it yourself with a good reference book that contains tables of nutrient content of foods. Once excellent source is an upcoming title by Dr. Allan Spreen, to be published in May. The name of the book is Nutritionally Incorrect: Why the American Diet is Dangerous and How to Defend Yourself From It. TH
July 07, 2005 04:22 PM
My kids are getting completely overloaded on sugar at school from meals and treats -- my daughter comes unglued and cant study. When i went to grade school, there was no lunch and no sweets available. What a change in society... Amanda Shrewsbury - Spring City, Utah...
You're right to be concerned about school food programs, especially since budget restrictions have led a number of districts to use major fast-food companies as food Service providers -- and even worse, to let soda companies stock school beverage machines.
Fortunately, the tide is starting to turn. Los Angeles is just one of a number of cities that are banning soda from their school buildings. Other districts are going so far as to offer organic lunches to there students. you may want to contact your school superintendent, as well as members of your local school board and let them know how you feel about what's best for your children.
June 23, 2005 10:49 AM
How many of us give the red hot chile pepper the respect it d e s e rves? Mo re often than not, most of us re g a rd red pepper or Capsicum as nothing more than the spice added to give Cajun and Mexican cuisine its piquant kick. Technically speaking, caye n n e pepper is the strongest red pepper variety of the Capsicum family, with paprika being the mildest.
Throughout this discussion, the terms capsicum and cayenne pepper will be used interchangeably. For our purposes, it’s important to know that herbalists have designated both of these terms for the same botanical agent. Health practitioners have known for centuries that Capsicum is much more than a culinary spice. Because they considered it a “ h o t” plant, Chinese physicians utilized it for physiologic conditions that needed stimulation. Capsicum or Cayenne Pepper is one of the few herbs that can be measured by its BTU or thermal units. In other words, it is a hot and stimulating pepper plant that can generate heat.
Recently, new and very valuable medicinal uses for Capsicum h a ve emerged through scientific inquiry. The red chile pepper is experiencing a rediscovery among health care practitioners, who have only just begun to uncover its marvelous therapeutic actions. It has been referred to as the purest and most effective natural stimulating botanical in the herbal medicine chest. The most recent clinical findings re g a rding Capsicum will be explored in our discussion with special emphasis on Capsicum’s ability to heal ulcers, protect stomach mucosa and alleviate peripheral pain. Unquestionably, Capsicum exe rts potent physiological and pharmacological effects without the side-effects commonly associated with powerful medicinal drugs. Ironically, in the past, Capsicum’s classification as a hot and spicy substance has done it a disService. Because Capsicum is fiery and pungent, it is frequently regarded as dangerous and unpalatable. To the contrary, if it is used properly, Capsicum can be perfectly safe and impressively effective against a wide variety of physical disorders ranging from indigestion to ulcers to migraines. It s ability to lower blood cholesterol, boost circulation and even step up metabolism are worth serious consideration. In addition, its value for mental afflictions like depression must also be assessed. In a time when the notion of treating disease after the fact is more the rule than the exception, Capsicum offers protection from infectious invaders by boosting the effectiveness of the immune system. Today, amidst the over prescription of antibiotic drugs, Capsicum emerges as a potent immune fortifier, antioxidant and infection fighter.
A powerful compound called capsaicin is what gives Capsicum its bite and is also responsible for most of its beneficial effects on human physiology.1 The hotter the pepper, the higher its content of capsaicin.2 The re m a rkable pro p e rties of capsaicin will be discussed and documented clinical evidence supporting the use of capsaicin will be delineated. It is important to realize in evaluating this herb that while it can be used alone, Capsicum is frequently added to herbal combinations to potentiate their overall action. This fact alone attests to the powerful but safe stimulant action of Capsicum. Stimulation is thought to be one of the keys to swift and complete healing. Capsicum is ascending in prestige and is regarded as a modernday botanical which is accruing new and impressive credentials. The fruit of this particular pepper plant is a valuable herbal treasure. It is vital to our health that we inform ourselves about its many medicinal uses.
CAPSICUM (CAPSICUM ANNUUM)
Common Names: Cayenne Pepper, Red Pepper, African Bird Pepper, Bird Pepper, Spanish Pepper, American Red Pepper Plant Parts: Fruit Active Compounds: alkaloids (capsaicin), fatty acids, flavonoids, volatile oil, carotene pigment Nutritional Components: Capsicum is rich in Vitamin C (ascorbic acid) and Zinc, two nutrients which are vital for a strong and healthy immune system. It is also high in vitamins, A, C, rutin (a bioflavonoid), beta carotene, iron, calcium and potassium. Capsicum also contains magnesium, phosphorus, sulphur, B-complex vitamins, sodium and selenium. The nutritional breakdown of Capsicum is as follows:
Pharmacology : Capsaicin (active component) contains over 100 distinct volatile compounds.3 It also contains capsacutin, capsaicin, capsantine, and capsico. Character: analgesic, antibacterial, antioxidant, antipyretic, antiseptic, antispasmodic, aromatic, astringent, blood thinner, cardiovascular tonic, carminative, circulatory stimulant, diaphoretic, hemostatic, herbal accentuator, nerve stimulant, stomachic and tonic (general) Body Systems Targeted : cardiovascular, circulatory, gastrointestinal, nervous, integumentary, skeletal, metabolic Herbal Forms: loose dried powder, capsulized, tincture, infused oil, ointment or cream Usage : Capsicum can be used liberally in a variety of forms. Capsulized dried Capsicum is probably the easiest and most practical way to take the herb. Commercial ointments can be purchased which contain from 0.025 to 0.075 percent capsaicin for the treatment of pain and psoriasis. Dried Capsicum can be mixed in hot water or can be used in tincture form, which can be added to water or juice. Safety: Capsicum is generally recognized as safe in the United Sates and has been approved as an over-the-counter drug. A four week feeding study of Capsicum concluded, “It appears that red chile is relatively non-toxic at the doses tested in male mice.”4 The seeds of the fresh Capsicum plant should not be ingested. Doses of Capsicum should be followed precisely as prescribed to avoid gast rointestinal upset. Pregnant women or breast feeding mothers should avoid using Capsicum. Initial use of topical Capsicum can result in some skin irritation or burning; howe ve r, clinical tests have found that this diminishes with continued application. Avoid direct contact with eyes or other mucous membranes in general.
America's Most Wanted
June 14, 2005 05:23 PM
America's Most Wanted
by Brian Amherst Energy Times, January 6, 2000
The United States eats well, a little too well, according to experts. Amply supplied with a large supply of high-calorie food, our diets might seem to be chock full of every conceivable nutrient. Well, to the question "Getting all the right vitamins, minerals and other nutrients?" the most appropriate answer seems to be "Not exactly." Eating a lot doesn't equal eating a lot of the most important vitamins and minerals. So, which vitamins and minerals are likely to show up in short supply in the typical American diet? Calcium certainly sits at the top of list. According to the most recent Continuing Survey of Food Intake by Individuals, which is conducted by the United States Department of Agriculture (USDA), women and girls age 12 and up are not consuming adequate calcium from their diet. Research reveals that about 1200 mg. day suffices for those over age 50 and 1000 mg a day should be adequate if you're between the ages of 19 and 50. Since strong bones are formed during "the first three decades of life," says Laura Bachrach, MD, of Since strong bones are formed during "the first three decades of life," says Laura Bachrach, MD, of Stanford University, ". . .osteoporosis is a pediatric disease." For long-range protection against that bone-weakening disease, kids should eat calcium-rich, low-fat dairy products and plenty of leafy greens (broccoli, cabbage, kale) as well as salmon (with bones), seafood and soy. But the calcium campaign does not end in early adulthood. Bone mass begins to deteriorate at about age 30. Menopausal hormonal changes can exacerbate bone brittleness. Medical conditions, including cancer, liver disease and intestinal disorders; prescription drugs; tobacco and alcohol indulgence; or a decline in activity, especially the weight-bearing kind, also jeopardize bone strength. According to the National Osteoporosis Foundation, about one in every two American women will break a bone after age 50 due to osteoporosis. That translates into about half a million fractured vertebrae and more than 300,000 shattered hips. Frequently, those breaks are life-threatening.
The critical role of calcium in many body functions is perhaps the most extensively clinically documented among nutrients. Researchers in the Department of Medicine, Oregon Health Sciences University in Portland, reviewed epidemiological and clinical studies conducted over the past two years on the relationship between dietary calcium and blood pressure (J Am Coll Nutr October 1999: 398S-405S). "Nearly 20 years of investigation in this area has culminated in remarkable and compelling agreement in the data," the researchers report, "confirming the need for and benefit of regular consumption of the recommended daily levels of dietary calcium." Investigators at the State University of New York, Buffalo School of Dental Medicine, presented results of their studies of calcium and vitamin C and gum disease at the June 26, 1998 meeting of the International Association for Dental Research. Two separate inquiries revealed that people who consumed too little calcium as young adults, and those with low levels of vitamin C in their diets, appear to have nearly twice the risk of developing periodontal disease later in life than folks with higher dietary levels of either nutrient.
Calcium: Much Documented Researchers offer extensive evidence of calcium's benefits on many fronts: n Osteoporosis poses a threat to older men as well as women, according to Randi L. Wolf, PhD, research associate at the University of Pittsburgh Graduate School of Public Health. Dr. Wolf presented her award-winning study to an October 3, 1999 meeting of the American Society for Bone and Mineral Research. Dr. Wolf suggests that men increase their consumption of calcium, particularly after age 80, to avoid age-related declines in the amount of calcium absorbed. According to Dr. Wolf, "It appears that the hormonal form of vitamin D, which is the main regulator of intestinal calcium absorption, may have an important role. We are conducting more research to better understand the reasons for why calcium absorption declines with age in men." n Scientists at Tufts University in Boston did some earlier work on the calcium-vitamin D connection and reported it in the September 4, 1997 New England Journal of Medicine. Using the National Academy of Sciences (NAS) increased recommended daily intake of 1200 milligrams of calcium and 400 to 600 international units of vitamin D for people over 50, the Tufts researchers found that with supplementation of the nutrients, men and women 65 and older lost significantly less body bone and, in some cases, gained bone mineral density. n Two studies published in American Heart Association journals show that atherosclerosis and osteoporosis may be linked by a common problem in the way the body uses calcium. The September 1997 Stroke revealed that, in a group of 30 postmenopausal women 67 to 85 years old, bone mineral density declined as atherosclerotic plaque increased. Researchers reporting in Circulation (September 15, 1997) advanced the theory that the osteoporosis-atherosclerosis connection may be related to a problem in handling calcium. n For people who had colon polyps removed, taking calcium supplements decreased the number of new polyps by 24% and cut the risk of recurrence by 19%, according to researchers at the University of North Carolina, Chapel Hill, School of Medicine. The study, published in the January 14, 1999 New England Journal of Medicine, was a first in crediting calcium with anti-cancer properties.
The D Factor
Without adequate vitamin D, your absorption of calcium slips and bone loss can accelerate, increasing the risk for fractures. Fifty percent of women with osteoporosis hospitalized for hip fractures at Brigham and Women's Hospital in Boston had a previously undetected vitamin D deficiency (Journal of the American Medical Association, April 28, 1999). University of Pittsburgh Cancer Institute researchers told participants at the April 14, 1997 meeting of the American Association for Cancer Research that vitamin D "significantly inhibits highly metastatic, or widespread, prostate cancer in animals," suggesting its potential for treating men with similar conditions. Few foods that Americans eat, except dairy, contain much vitamin D, but we can usually synthesize sufficient amounts from as few as five minutes' exposure to the sun. But as skin ages, its ability to act as a vitamin D factory decreases. According to Michael F. Holick, the director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center, upwards of 40% of the adult population over age 50 that he sees in his clinic are deficient in vitamin D. Recently, the National Academy of Sciences (the official body that decrees the required amounts of necessary nutrients) increased the daily recommendations of vitamin D to 600 IU for people over 71, 400 IU for those aged 51 to 70 and 200 IU for people under 50. The best dietary sources, apart from dependable supplements, are dairy and fatty fish like salmon. Four ounces of salmon provide about 300 IU.
The Facts About Fats
The American lust for low-fat, high-carbohydrate diets filled with sugary foods has exploded into nothing short of "obsession," according to experts at the General Research Center at Stanford University Medical Center (Am J Clin Nutr 70, 1999: 512S-5S). That mania oftens robs us of the crucial balance of omega-3 and omega-6 fatty acids typical of the Mediterranean diet that protect us from heart disease by controlling cholesterol and making blood less likely to form clots. These fatty acids cannot be made by the body but are critical for health: n Omega-3 fatty acid (linolenic acid) comes from fresh, deepwater fish (salmon, mackerel, sardines) and vegetable oils such as canola, flaxseed and walnut. n Omega-6 fatty acid (linoleic acid) found primarily in raw nuts, seeds and legumes and in saturated vegetable oils such as borage, grape seed, primrose, sesame and soybean. The American Heart Association recommends limiting total fat consumption to 30% of daily calories. Saturated fats like those in dairy and meat products as well as vegetable oil should comprise 10% of total calories; total unsaturated fat (fish oils, soybean, safflower nuts and nut oils) should be restricted to 20 to 22% of daily calories.
Be Sure About B12
Vitamin B12 presents a particular problem for the elderly because older digestive systems often don't secrete enough stomach acid to liberate this nutrient from food. (The elderly have no problem absorbing B12 from supplements, because it's not bound to food.) Vitamins generally moderate the aging process but, ironically, that process and the diseases that frequently accompany it affect vitamin metabolism (Schweiz Rundsch Med Prax 83, 1994: 262-6). And because of those changes, we need more of certain vitamins. This is the case for vitamins D, B6, riboflavin and B12. Crucial for health, B12 is necessary to prevent anemia, and, according to recent studies, needed (along with folate and B6) to help stave off heart disease. B12, with thiamine and niacin, boosts cognition (Adv Nutr Res 7, 1985: 71-100). Screening for vitamin B12 deficiency and thyroid disease is cheap and easy and can prevent conditions such as dementia, depression or irreversible tissue damage (Lakartidningen 94, 1997: 4329-32). In the January 5-12, 1999 issue of Circulation: Journal of the American Heart Association, the AHA urged doctors to screen levels of homocysteine (the amino acid byproduct of protein digestion that damages arteries, causes heart disease and, possibly, strokes) in patients at high risk for heart disease. They also recommended all Americans to up their daily levels of vitamins B6 and B12, as well as folic acid. Since fruits, vegetables or grains lack B12, vegetarians need B12 supplements. And they're a good idea for the rest of us, too.
Folic Acid Benefits
Folic acid made headlines in the early 1990s when the U.S. Public Health Service declared that "to reduce the frequency of neural tube defects [spina bifida, or open spine, and anencephaly, a lethal defect of the brain and skull] and their resulting disability, all women of childbearing age in the United States who are capable of becoming pregnant should consume .4 milligrams (400 micrograms) of folic acid per day." This recommendation followed voluminous research that showed taking folic acid was associated with a significantly reduced risk of birth defects. (The advisory is based on the fact that nearly half of all pregnancies are unplanned. If you think you are pregnant, consult your health practitioner for supplementary advice.)
A Team Player
Folic acid's efficacy intensifies when it works with other nutrients. Among many studies on the preventive powers of folic acid on birth defects, one published in The New England Journal of Medicine (327, Dec. 24, 1992: 1,832-1,835), disclosed an even greater decrease in neural tube defects when supplements of folic acid contained copper, manganese, zinc and vitamin C. As a warrior against homocysteine, folic acid joins the battalion of B12 and B6 in detoxifying this harmful protein. At the University of Washington's Northwest Prevention Effectiveness Center, researchers recently analyzed 38 published studies of the relationship between folic acid, homocysteine and cardiovascular disease and, according to associate professor Shirley A. Beresford, MD, folic acid and vitamin B12 and B6 deficiencies can lead to a buildup of homocysteine.
Canadian researchers reported in the Journal of the American Medical Association (275, 1996: 1893-1896) that men and women with low folic acid have a 69% increase in the risk of fatal coronary heart disease. This 15-year study of more than 5,000 people stressed the need for dietary supplementation of folic acid. Folic acid also has been credited with the potential to protect against cancers of the lungs, colon and cervix. It appears to help reverse cervical dysplasia, the precursor cells to cervical cancer, especially for women taking oral contraceptives, which may cause a localized deficiency of folic acid in the cells of the cervix. According to Shari Lieberman, PhD, and Nancy Bruning, authors of The Real Vitamin & Mineral Book (Avery), folic acid derivatives work with neurotransmitters, the chemicals that permit signals to be sent from nerve fiber to nerve fiber. A lack of folic acid can cause some nervous-system disorders, such as depression, schizophrenia and dementia; it also may be related to some forms of mental retardation. Other supporting roles of folic acid, according to researchers: the formation of normal red blood cells, important for preventing the type of anemia characterized by oversized red blood cells; strengthening and improving white blood cell action against disease; limiting production of uric acid, the cause of gout.
The Best Sources
Many foods are rich in folic acid: beef, lamb, pork and chicken liver, spinach, kale and beet greens, asparagus, broccoli, whole wheat and brewer's yeast. But experts believe that only 25 to 50% of the folic acid in food is bioavailable. Processing also reduces an estimated 50 to 90% of its content. Folic acid supplementation overcomes these obstacles with little risk, as it has no known toxicity. Women taking folic acid who are current or former users of oral contraceptives may require additional zinc. And be sure to augment your folic acid supplement with its synergistic counterpart, vitamin B12.
Focus on Fiber
The American Heart Association came out squarely behind fiber in a June 16, 1997 issue of its journal Circulation: Double your daily intake to lower cholesterol and the risk of heart disease. The American diet is consistently low in fiber, notes Linda Van Horn, PhD, RD, author of the article. Twenty-five to 30 grams a day from foods (or supplements) are not only heart healthy but seem to aid weight control.
Getting enough iron? An estimated 25% of adolescent girls in the United States are iron deficient, according to an October 12, 1996 issue of the British medical journal The Lancet, which reported that girls who took iron supplements performed significantly better on verbal tests than those who took a placebo. "Teenage girls should be regularly tested for iron deficiency because rapid growth and the onset of menstruation during puberty increase the body's need for iron," says Ann Bruner, MD, of the Johns Hopkins Children's Center and a lead author of the study.USDA data reveal that women up to age 50 also tend to get much less than recommended levels of iron, a lack of which leads to anemia, a deficiency of red blood cells, hemoglobin or volume of blood. For kids, deficiency is more common from six months to four years and during the rapid growth spurts of adolescence when the body is growing so quickly that the body's iron stores may sink to dangerous levels. Vegetarian women run the greatest risk for deficiency, as meat is iron-rich; foods like beans, grains and vegetables also contain some iron. Supplements, of course, supply easily absorbable iron. And to absorb iron from vegetarian sources, take vitamin C with your meals. That boosts the amount of this mineral you will take in. Bear in mind, however, that certain folks-older men and post-menopausal women-generally have adequate dietary supplies of iron. Of greater concern, in fact, is excessive iron, and for these folks iron-free multivitamin and mineral supplements are available.
Ante Up the Antioxidants
Antioxidant nutrients help protect the body from oxygen-scavenging molecules called free radicals. The products of pollution, the body's own metabolic processes and other sources, free radicals are linked to heart disease, cancer and other chronic health problems. The most important antioxidants, which include vitamin C, E, beta carotene, and selenium, are often lacking in the American diet. Plus, optimal amounts of vitamin E cannot be consumed from food. You need supplements. The bottom line: even though we live in a land of plenty, you can still miss vital nutrients. So make sure to consume these vital substances.
Source of Missing Nutrients In the search for the nutrients missing from America's diet, one big help is the sprout. The sprout is truly one of nature's heavyweights: fresh, tiny and moist, its power punch of vitamins, minerals, protein, chlorophyll and disease-busting phytochemicals land it in a weight class far beyond that of its full-grown competitors. Size does NOT matter to this nutritional giant. A championship belt currently wraps around the miniscule broccoli sprout, catapulted into the ring by Paul Talalay, MD, professor of pharmacology and molecular sciences at Johns Hopkins University. Dr. Talalay discovered that the seedlings contain substantially more of the cancer-fighting substance sulforaphane than mature plants (Proc. Natnl. Acad. Sci. USA, 94, 10367-10372). Sprouts, the quintessential health food of the Sixties, provide a wonderfully varied and versatile way to get your daily greens. Raw or cooked, strong or mild, vegetable and grass sprouts and their algae cousins add low-calorie texture to recipes and a rich, diverse complement of nutrients and fiber.
Ancient Asia to the Modern Lab
Asians stir-fried sprouts as one of the earliest fast foods as long as 5,000 years ago. The ancient Chinese relied on sprouts for year-round vegetables in colder regions of their vast country. Today, researchers studying sprouts and adult plants have identified their important chemoprotective and other health-bolstering substances. In Paul Talalay's research project at Johns Hopkins, scientists found that three-day-old broccoli sprouts contain up to 50 times more sulforaphane than mature plants, which prompts the body to produce an enzyme that prevents cancer tumors from forming. Uniform levels of the compound saturate the shoots, unlike the chemically uneven adult plants. The Brassica family of broccoli and cabbage is richly endowed with phytochemicals that also help reduce estrogen levels associated with breast cancer. Other phytochemical compounds in the Brassica family are associated with the prevention of stomach and lung cancers. Most of the initial landmark work on phytochemicals' cancer-fighting powers has taken place since 1989 under the aegis of the National Cancer Institute's "Designer Food Program," which isolated, for example, the isoflavones in beans that seem to neutralize cancer-gene enzymes.
Strong Suit: Soy and Spirulina
The isoflavones and phytosterols in soy produce an estrogenic effect that appears to relieve menopausal symptoms and help prevent breast cancer. Soy foods expert Mark Messina, PhD, has done extensive work on the subject, some of which has been published in the Journal of the National Cancer Institute 83, 1991: 541-6. Researchers also have synthesized a bone-strengthening form of soy isoflavones called ipriflavone, following impressive clinical trials in the treatment of osteoporosis (American Journal of Medicine, 95 [Suppl. 5A] (1993): 69S-74S). Spirulina and other micro-algae are fascinating organisms that inhabit a niche between the plant and animals kingdoms. Named for its tiny spirals, spirulina, a blue-green algae, grows in saline lakes but is cultured for maximum nutritional content. In her book Whole Foods Companion (Chelsea Green), Dianne Onstad notes that spirulina contains "the highest sources of protein, beta carotene and nucleic acids of any animal or plant food." Its nucleic acids, she says, benefit cellular regeneration; its fatty acids, especially GLA and omega-3 acids, make it one of the most complete foods. Sprouts, like any other produce, should be rinsed thoroughly before serving. People at high risk for bacterial illness-young children, the very elderly or folks with weakened immune systems-should limit their consumption of raw sprouts. But no matter how you eat them, you may find more spring in your step from these tiny, sprouting nutritional wonders.
Cleanse That Body!
June 14, 2005 11:59 AM
Cleanse That Body! by Lisa James Energy Times, January 6, 2005
When toxins accumulate in your tissues, you can become fuzzy and sluggish. Here's how a New Year's internal cleansing can make you feel fresh and energized.
What's your New Year's resolution? Losing weight? Getting fit? Kicking the [fill-in-the-blank] habit? Whatever the shape of your dreams for 2005, it won't be easy launching a self-improvement program unless you give your body a fresh start. Where to begin? Detoxification-an internal cleansing that can supply the energy you need to succeed in achieving your goals.
No one can avoid toxins in our contaminated world, so many of us suffer from toxic overload, which can lead to fatigue, digestive problems and reduced immune function. " When we get out of balance, we get congested and toxic," says Elson Haas, MD, founder of the Preventive Medical Center of Marin in San Rafael, California (www.elsonhaas.com), and author of The New Detox Diet (Celestial Arts), "and our bodies' regular elimination systems cannot keep up with it. We have problems with our skin, our intestines, our sinuses. We also become deficient in vitamins, minerals and essential fatty acids. Most people have both congestion and deficiency, and they would benefit greatly from detoxification."
Toxins Within, Toxins Without
Life's fundamental activities-breathing, eating, walking around-generate waste in the form of free radicals, the unstable molecules that can ravage cells and tissues. What's more, Dr. Haas says that just "being under stress, being afraid, being anxious all produce more free radicals in the body" (like when a work deadline hits on the same day your car dies). When you add to your internal toxins all the noxious items coming from the outside, including the dietary ones, the recipe is very unhealthy.
" People are making poor choices in what they're putting in their mouths," says Dr. Haas. "They're taking in too much refined flour and sugar. There's a common problem in our country I call 'obese malnutrition'-people eating too many calories and not getting enough nutrition. People do a lot of junky fats and have a deficiency in the essential fatty acids that help protect cells."
Our bodies are also awash in manmade poisons such as food preservatives and additives, and residues from pesticides and herbicides. "The amount of toxic chemicals we are exposed to in our environment is staggering," says Susan Lark, MD, clinical nutrition expert and author of The Chemistry of Success (Bay Books). She notes that the average American is exposed to 14 pounds of such assorted chemical junk each year.
The body, however, does do its own housekeeping-and all of our cells detoxify every second of every day. "It's always a balance of garbage in, garbage out," says Dr. Haas, who has 30 years of experience in helping people detoxify. "Some of the toxins we break down into smaller components, some we just dump into the intestines for elimination."
Problems arise when there's more dirt than the internal maid Service can sweep away. Dr. Lark notes that toxins wind up being stored in cells, especially fat cells, where they can hang out for years. When they are finally released "during times of low food intake, exercise or stress" complaints can range from tiredness to dizziness (sound familiar?).
That's where detoxification comes in, says Dr. Haas: "I think detoxification is a vital health care tool, particularly in this day and age when people are exposed to too many chemicals."
The process of detoxification starts with cleansing the intestinal system. Alternative health practitioners observe that discombobulated bowels can become overly permeable (a condition called leaky gut syndrome) and allow in all sorts of things that they shouldn't, such as semi-digested food particles, leading to inflammation and complaints that include rashes and joint pain.
Cleansing can be as simple as cutting down on what Dr. Haas calls the SNACCs-Sugar, Nicotine, Alcohol, Caffeine and Chemicals-or as thorough as a complete diet-and-supplement program with colonic irrigation (a sort of super-enema, professionally administered; if you're interested, contact the International Association of Colon Hydrotherapy at 210-366-2888 or www.i-act.org). The more powerful the program, though, the more likely you are to experience toxicity reactions such as nausea and headaches because of the volume of material being released. As Dr. Haas puts it:
" If you did water and green salads for a week, you'd detoxify more intensely than if you just gave up sugar and white flour." If you're feeling extremely rundown, take a gentle approach at first or consult a nutritionally aware practitioner, especially if you have a preexisting medical condition.
Getting more fiber is essential. Laurel Vukovic, a natural health teacher and author of 14-Day Herbal Cleansing (Prentice Hall), suggests following this daily regimen for two weeks: a teaspoon of psyllium (a fiber supplement); at least seven daily servings of fruits and vegetables, especially fiber-rich ones like apples, cabbage and carrots; and six glasses of water, along with daily exercise. Extra fiber "supports the intestines in eliminating the larger amounts of toxins that are released," says Vukovic, "prevent[ing] their reabsorption into the bloodstream." Some people find premixed cleansing formulas convenient; check your health food store shelves.
Fasting is a more intense detox approach that, according to Dr. Haas, "promotes relaxation and energization of the body, mind and emotions, and supports a greater spiritual awareness." He especially recommends fasting in the spring and autumn, which are times of transition. Some people do water-only fasts, but fresh vegetable juices are probably a better option, particularly if you haven't fasted before. Juices and plenty of fresh water also help cleanse the kidneys, another vital detox route.
Instead of juices you can use a special cleansing formula, such as the Spring Master Cleanser: 2 tablespoons freshly squeezed lemon juice, 1 tablespoon pure maple syrup and 1/10 teaspoon cayenne pepper in 8 ounces of spring water. Dr. Haas recommends drinking eight to 12 glasses daily (and rinsing your mouth after each glass to protect your teeth from lemon's acids), augmented by water, laxative herb tea, and peppermint or chamomile tea.
Try fasting for a day to see how you feel. Dr. Haas suggests starting out by fasting from early evening through the night, and eating a light breakfast the following day. Subsequent fasts can gradually increase in length-experienced fasters may go up to two weeks without food.
Break your fast properly; for juice or cleansing formula fasts, eat a raw or cooked low-starch vegetable, such as spinach or other greens. "Go slowly, chew well and do not overeat or mix too many foods at any meal," says Dr. Haas.
Don't forget your liver, the organ that transforms noxious chemicals into substances your body can eliminate. The herb milk thistle, used since ancient times as a liver tonic, contains silymarin, which protects the liver from pollutants and helps it renew itself after toxic damage. Dandelion not only promotes the flow of bile from the liver, which helps clean out the junk, but also acts as a diuretic, helping the kidneys do their job. Green-food supplements, such as spirulina and cereal grasses, help neutralize toxins.
To maintain your cleansing gains, eat a healthy diet after detoxing. Focus on fresh organic foods, especially produce, beans and peas, whole grains and seeds (add organic poultry if you eat meat). Organic yogurt provides healthful probiotics, while fresh fish and ground flaxseeds provide omega-3 fats.
Clean Living Pays
The body's largest organ-the skin-provides a valuable contaminant exit path. Sitting in a hot tub or sauna "benefits the internal organs of detoxification," according to Dr. Lark, "by lessening the amount of toxins they must process." When sweatin' out the bad stuff, drink plenty of water and replace the calcium, magnesium and potassium lost through perspiration.
Another way to stimulate skin circulation is dry brushing, which also removes dead skin cells for a healthy glow (and is easier to fit into a daily routine). Using "a moderately soft, natural vegetable-fiber bristle brush" (Dr. Lark's suggestion), work in from the hands and up from the feet with light, short strokes that always move towards the heart. Vukovic says that a hot towel scrub is another option; put three drops of lavender essential oil in a basin of very hot water, dip in a rough terry washcloth and wring out, and then rub the skin briskly, starting with your feet and working your way up.
Once you've detoxified your body, you can start in on your immediate surroundings. Dr. Haas warns against using plastic food storage containers: "When food is heated in plastics some of the plastic material ends up in the food, especially if the food contains acids." Use glass containers instead. He also recommends avoiding aluminum pots and pans, and using stainless steel as an alternative.
Dr. Haas has seen what a good detox program can do: "It's amazing the kind of results people get-looking and feeling younger, more vital and healthy. They say, 'I'm sleeping like a baby,' they have fewer aches and pains. They have more peace in their bodies. I think detoxification is one of the keys to preventive medicine." So cleanse that body and let detoxification bring balance and renewal to your life.
June 13, 2005 01:18 PM
by Cal Orey Energy Times, August 2, 1999
Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery.
More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering.
Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame.
According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life.
The good news: Research shows that diet and lifestyle can lower your risk of depression.
Birth of the Blues
Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes.
Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression.
The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours.
Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5).
Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast.
NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions."
Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression.
"SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York.
Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e."
(Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.)
SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant.
For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14).
5-HTP: Another popular supplement to boost mood and relieve depression is hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand.
"One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts.
St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that hypericum produced fewer side effects than conventional anti-depressants.
Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers.
"In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner.
Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve."
Amino Acid Help
Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity.
For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety.
The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine.
In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress.
Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.)
Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins.
For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally.
Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99).
"Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers.
If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.
You Are What You Digest
June 10, 2005 04:50 PM
You Are What You Digest
by Anthony J. Cichoke, DC Energy Times, September 2, 1999
Does your dinner creep back to haunt you in the ghostly morning hours? Does a mere glance in the direction of the local Mexican cafe or barbecue palace fill you with dread (to say nothing of internal discomfort)?
We tend to ignore our digestive systems-the ever-ready, always reliable iron-clad stomachs of our youth, into which we stuffed pizza, peppers and beer-until diarrhea, gas, heartburn, bloating, constipation, stomach pain or other, much more serious, problems develop.
According to the National Institutes of Health, more than 62 million Americans experience some type of digestive distress. More than 10 million people suffer from hemorrhoids, nearly 3 million from gastritis and duodenitis, 2.3 million from inflammatory bowel disease, almost 4.5 million from constipation and 1.4 million from irritable colon. (Statistics from Digestive Diseases in the United States: Epidemiology and Impact, edited by James E. Everhart and published in 1994 in Washington, DC, by the US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases.)
Many conditions such as hemorrhoids or constipation are relatively benign, while others, notably chronic liver disease, malignancies and ulcers, can be life-threatening.
In my long career as a chiropractor with an intense interest in nutrition, I have studied and written about the powers of enzyme therapy to prevent and treat the common and related problems of indigestion, heartburn, gas, lactose intolerance and constipation.
Poor Digestion: The Costs
Impaired digestion takes a dangerously high toll in causing nutrient deficiencies. For example, the stomach needs sufficient hydrochloric acid to activate the digestive enzyme pepsin, a substance which helps break down the proteins you eat into the short chains of amino acids (protein building blocks) that go into strong muscles, fight disease and produce a healthy supply of blood.
Poor digestion can also impair your absorption of carbohydrates and fats as well as many vitamins and minerals. Vitamin E, for example, is fat soluble, that is, stored for long periods in the body's fat cells, rather than rapidly excreted like the water soluble vitamin C.
Impaired pancreatic function, or insufficient lipase or bile production, will inhibit fat digestion, possibly causing insufficient absorption of vitamin E, according to the book Present Knowledge in Nutrition (International Life Sciences Institute, Nutrition Foundation, Washington, DC), which is edited by Myrtle L. Brown.
Thus, any difficulty in digesting and absorbing dietary fat can appreciably decrease vitamin E digestion and absorption. In fact, insufficient fat intake coupled with troubled digestion and absorption can affect the body's use of all the fat soluble vitamins-A, D, E and K.
The Enzyme-Digestion Team
Enzymes are molecules naturally produced by the body. These dynamos are involved in all physiological functions but are probably best known for the many jobs they perform during the process of digestion.
Digestive enzymes break the food you eat down into smaller particles so the body can better absorb vitamins, minerals and other nutrients. Unfortunately, in many cases, we may become deficient in digestive enzymes. Or, on the other hand, the enzymes we do produce may be inadequate for proper digestion. Luckily, supplemental enzymes can compensate for nature's shortfalls.
Supplemental enzymes, available in tablets, capsules, powders and pills, can help enhance the digestive process. The most popular enzymes for this use include:
Proteases help the body digest proteins by breaking them down into their component amino acids.
Lipases break down fat molecules into smaller pieces for better digestion.
Amylases break down carbohydrates.
Digestive enzymes also function in a wide variety of ways:
They detoxify and cleanse the colon and stimulate the beneficial bacteria in the gut, thereby helping relieve a number of digestion-related disorders.
They help mobilize and remove toxic products from the body.
Supplemental enzymes can be used in basically three ways: as digestive aids, taken with or just prior to meals to help break down foods, freeing their nutrients for absorption and use by the body; as systemic enzyme therapy taken between meals and intended to be absorbed into the bloodstream and carried throughout the body to work intensively and thoroughly at the cellular level. They are consumed between meals to avoid mixing them with food as it is consumed.
Enzymes used systemically can energize the digestive, immune, cardiovascular and nervous systems. In addition, they can also help fight viruses, bacteria, toxins and inflammation, a common symptom with many digestive disorders including diverticulitis and gastritis.
The third way to take supplemental enzymes is in a form I call Enzyme Absorption System Enhancers (EASE), commercially produced enzymes combined with herbs, vitamins, minerals and other nutrients designed to improve their activity, absorption and bioavailability (readiness and ease with which the body can take them up).
Enzymes for Common Conditions From my extensive research and experience, enzymes as digestive aids, in systemic enzyme therapy as as EASE, can treat more than 150 common health conditions.
Choose your enzyme supplements carefully, scrutinizing the label thoroughly for:
directions for use formulation (coated or uncoated) the enzymes in the formulation and their sources; a vegetarian would want to avoid enzymes from animal sources and those with allergies should ensure that the formulation is free of potential allergens. However pervasive digestive problems are, there's no reason why they have to get you down, ruin your digestion or inflate you. These are very useful substances: Enzymes can set your digestive system - and most of your body's functions - back on track.
Remember, enzymes are essential keys to the smooth, efficient function of that wonderful machine, the human body. Because enzyme production and activity decrease with age, trauma and illness, make a firm commitment to daily enzyme supplementation for a healthier, happier, longer life.
Mother's Choice with Iron - Scientific Prenatal Nutrition!
June 03, 2005 06:23 PM
You’re expecting a baby—and right now nothing could be more important than ensuring the health of your developing child. At this crucial time, what could be more basic than providing the nutrients that are the very substance of the new life you’re carrying? At every critical stage of pregnancy, your baby’s cells and tissues are literally formed from the nutrients you take in. Source Naturals is deeply committed to giving your newborn every chance for optimal health. That’s why we developed MOTHER’S CHOICE Prenatal Multiple. MOTHER’S CHOICE combines a comprehensive vitamin-mineral blend with advanced nutrients that reflect the latest scientific research. And each bottle comes with a separate package of Arctic Pure™ DHA softgels. DHA is a fatty acid that is crucial for baby’s brain development from the earliest stages of pregnancy through the breastfeeding years. MOTHER’S CHOICE also supports your health and vitality, with a blend of traditional herbs used for centuries to relieve morning sickness and leg edema. MOTHER’S CHOICE: because nothing is too good for you and your baby.
Go the Source for Scientifically Based Formulation
MOTHER’S CHOICE PRENATAL MULTIPLE was expertly formulated to supply a full range of essential vitamins and minerals, in potencies effective for maternal health and fetal development, while safe for the fetus.
Healthy Fetal Development
MOTHER’S CHOICE contains ingredients that reflect the latest findings in fetal nutrition.
Enjoy Your Special Time!
Pregnancy should be one of the high points of your life, but typical discomforts can get in the way. MOTHER’S CHOICE features herbs traditionally used during pregnancy. Morning Sickness: Ginger root and peppermint leaf are traditional remedies for the nausea associated with morning sickness, and chamomile has soothing properties. Leg Comfort: Vitamin E has been shown to relieve nocturnal leg cramps, while bilberry supports healthy capillaries and veins.
Take Charge of Your Pregnancy
Source Naturals understands your deep desire to safeguard your baby’s health and development. With MOTHER’S CHOICE you have the resources to act on that concern. MOTHER’S CHOICE: for a vibrant pregnancy and a good start on life for your newborn.
CAUTION: Pregnant or breastfeeding women should consult a health care professional before using this or any dietary supplement.
Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
May 24, 2005 09:52 AM
Cognitive Improvement in Mild to Moderate Alzheimer's Dementia After Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Maria De Jesus Moreno Moreno, MD Instituto Nacional de la Senectud, Mexico City, Mexico
in both men and woman they consistently improved after 90 and 180 days versus baseline with adiministration of GPC three times a day, whereas in the placebo group they remained unchanged or worsened. Statistically significant differences were observed between treatments after 90 and 180 days.
Bartus RT, Dean RL III, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction, Science. 1982;217:408-414. 2. Larson EB, Kukull WA, Katzman RL. Cognitive impairment: Dementia and Alzheimer's disease. Annu Rev Public Health. 1992;13:431-449. 3. Hofman A, Rocca WA, Brayne C, et al, for the European Prevalence Research Group. The prevalence of dementia in Europe: A collaborative study of 1980-1990 findings. Int d Epidemiol. 1991;20:736-748. 4. Blackwood W, Corsellis JAN, eds. Greenfield's Neuropathology. 3rd ed. London: Arnold; 1976. 5. Geldmacher DS. Cost-effective recognition and diagnosis of dementia. 5emin Neurol. 2002;22:63-70. 6. Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459. 7. Perry EK. The cholinergic hypothesis--ten years on. Br Med Bull. 1986;42:63-69. 8. Giacobini E. From molecular structure to Alzheimer therapy. Jpn d Pharmacol. 1997;74:225-241. 9. Giacobini E. Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: From tacrine to future applications. Neurochem Int. 1998;32:413-419. 10. Brinkman SD, Smith RC, Meyer JS, et al. Lecithin and memory training in suspected Alzheimer's disease. J Gerontol. 1982;37:4-9. 11. Davis E, Emmerling MR, Jaen JC, et al. Therapeutic intervention in dementia. Crit Rev Neurobiol. 1993;7:41-83. 12. Amenta E Parnetti L, Gallai V, Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropiate approaches? Mech Ageing Dev. 2001;122:2025-2040. 13. Sigala S, Imperato A, Rizzonelli P, et al. k-Alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eurd Pharmacol. 1992;211:351-358. 14. Govoni S, Battaini E Lucchi L, et al. Effects of alpha-glycerylphosphorylcholine in counteracting drug-induced amnesia: Through cholinergic and non-cholinergic mechanisms [in Italian]. Basi Raz Ter. 1991;21:75-78. 15. Canonico PL, Nicoletti F, Scapagnini U. Neurochemical and behavioral effects of alpha-glycerylphosphorylcholine [in Italian]. Basi Raz Te~ 1990;20: 53-54. 191 CLINICAL THERAPEUTICS ® 16. Parnetti L, Amenta E Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: An analysis of published clinical data. Mech Ageing Dev. 2001;122:2041-2055. 17. Venn RD. The Sandoz Clinical Assessment-Geriatric (SCAG) scale. A general-purpose psychogeriatric rating scale. Gerontology. 1983;29:185-198. 18. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991;19:330-341. 19. Frattola L, Piolti R, Bassi S, et al. Multicenter clinical comparison of the effects of choline alphoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia. Curt Ther Res Clin Exp. 1991;49:683-693. 20. Muratorio A, Bonuccelli U, Nuti A, et al. A neurotropic approach to the treatment of multi-infarct dementia using L-c~-glycerylphosphorylcholine. Curt Ther Res Clin Exp. 1992;52:741-75l. 21. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: APA; 1994. 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. 23. Folstein ME Folstein SE. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198. 24. Loeb C, Gandolfo C. Diagnostic evaluation of degenerative and vascular dementia. Stroke. 1983;14:399-401. 25. Hamilton M. A rating scale for depression.J Neurol Neurosurg Psychiatry. 1960;23:56-62. 26. Hamilton M. Development of a rating scale for primary depressive illness. BrJ Soc Clin Psych& 1967;6:278-296. 27. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. AmJ Psychiatry. 1984;141:1356-1364. 28. Reisberg B, Ferris SH, De Leon MJ, et al. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry. 1982;139:1136-1139. 29. National Institute of Mental Health. Clinical global impressions. In: Guy W, ed. ECDEU Assessment for Psychopharmacology. Revised edition. Rockville, Md: National Institute of Mental Health; 1976:217-222. 30. Burns A, Russell E, Page S. New drugs for Alzheimer's disease. Br J Psychiatry. 1999;174:476-479. 31. Kumar V, Anand R, Messina J, et al. An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors. Eur J Neurol. 2000;7:159-169. 32. Knapp MJ, Knopman DS, Solomon PR, et al, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991. 192 M. Moreno 33. Lindstrom MJ, Bates DM. Newton-Rapshon algorithms for linear-mixed effects models for repeated measure data. J Am Stat Assoc. 1998;83:1014-1022. 34. Thai LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology 1996;47:705-711. 35. Rogers SL, Friedhoff LT, for the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303. 36. Rogers SL, Doody RS, Mohs RC, Friedhoff LT, for the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158:1021-1031. 37. Corey-Bloom J, Anand R, Veach J, for the ENA 713 B352 Study Group. A randomized trial evaluating the efficacy and the safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1:55-65. 38. Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. BMJ. 1999;318: 633-638. 39. Amenta E Bronzetti E, Del Valle M, Vega JA. Effects of alpha-glycerylphosphorylcholine in neuroanatomy of aging brain in experimental animals [in Italian]. Basi Raz Te~: 1990;20:31-38. Address correspondence to: Scientific Department, Italfarmaco SpA, via dei Lavoratori 54, 20092 Cinisello Balsamo, Milan, Italy.
Under-Reported (and Underappreciated) Cholesterol control.
May 12, 2005 10:00 AM
Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Controlby Richard Conant, L.Ac., C.N.
Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.
The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.
Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.
The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)
Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.
Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.
How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look.
In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.
Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."
Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.
Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.
Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.
Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6
Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.
When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.
There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12
We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.
Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.
The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."
It would be a tremendous Service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.
1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.
2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.
3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.
4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.
5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.
6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.
7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.
8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.
9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.
10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.
11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15.
12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3.
13. Serbinova, E., et. al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275.
14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.
Control Cholesterol with the following Supplements