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	Happy news: Curcumin outperforms prozac for reducing symptoms ofdepression	Darrell Miller	1/25/19
	Australian father treats his daughters' Chron's disease by juicing cannabis... then gets raided by the government	Darrell Miller	4/22/18
	Vitamin C Treatment of Whooping Cough	Darrell Miller	11/1/17
	Organic onions richer in flavonoids	Darrell Miller	7/8/17
	MedDiet Protects Against Atherosclerotic Plaque	Darrell Miller	6/12/17
	Cancer-killing Dandelion Tea Receives $157K Research Grant	Darrell Miller	5/18/17
	Scientists stunned as dried leaves achieve 100% CURE RATE among critically ill MALARIA patients after all pharma drugs failed	Darrell Miller	4/29/17
	5 Things to Know About Genetic Testing Bill	Darrell Miller	3/24/17
	Research Proving Cannabis Kills Cancer Cells Safely has been Suppressed Since 1974	Darrell Miller	3/15/17
	What are heart failure, heart attack and cardiac arrest?	Darrell Miller	2/14/17
	Omega-3 intake may aid in recovery of concussions and brain injury	Darrell Miller	12/13/16
	Top Vitamin and Mineral Deficiencies — Are You at Risk? - ProHealth	Darrell Miller	12/5/16
	The Health Benefits of Grape Seed Extract	Darrell Miller	11/14/16
	Myrrh oil health benefits	Darrell Miller	2/21/14
	Herbs For Depression: Alternative Solutions To Improve Your Mood	Darrell Miller	2/17/12
	The Benefits of Stevia for Diabetics	Darrell Miller	2/5/12
	Does Stress Deplete The Body Of Minerals?	Darrell Miller	9/24/11
	Honey from bee's	Darrell Miller	7/1/09
	Calcium, Magnesium And Vitamin D	Darrell Miller	6/24/09
	BoneSet For Fevers	Darrell Miller	6/9/09
	Inositol And Choline	Darrell Miller	12/11/08
	Hoodia Gordonii	Darrell Miller	12/10/08
	Panax Ginseng	Darrell Miller	9/22/08
	Grapefruit Seed Extract	Darrell Miller	5/6/08
	Big Pharma Plays God, Stealing and Altering Pant Compounds making Synthetic Drugs	Darrell Miller	1/2/08
	Milk Thistle May Help With Cirrhosis, Gallstones, and Hepatitis Liver Problems	Darrell Miller	11/14/07
	7-Keto, The Next Dhea With No Side Effects	Darrell Miller	11/10/07
	Omega-3 Relieves Depression in Some Individuals	Darrell Miller	11/2/07
	Artemisinin For Better Health And Wellness	Darrell Miller	10/25/07
	Pumpkin Seed Oil is good for your health	Darrell Miller	10/14/07
	B Vitamins Avert Stroke, Coronary Disease, Death	Darrell Miller	1/25/06
	PYCNOGENOL AS A DIETARY SUPPLEMENT	Darrell Miller	7/13/05
	OBESITY: A 2Oth- Century Plague	Darrell Miller	6/25/05
	GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....	Darrell Miller	6/21/05
	Hearty Soy - Soy will cater to your cardiovascular well-being...	Darrell Miller	6/13/05
	Cholesterol Conundrum	Darrell Miller	6/10/05
	the effect of vinpocetine on cerebral blood flow (CBF) ...	Darrell Miller	5/26/05
	Under-Reported (and Underappreciated) Cholesterol control.	Darrell Miller	5/12/05
	Red Yeast Rice can Lower Cholesterol. Scientific Studies prooven	Darrell Miller	5/9/05

Date: January 25, 2019 10:22 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Happy news: Curcumin outperforms prozac for reducing symptoms ofdepression

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Date: April 22, 2018 05:17 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Australian father treats his daughters' Chron's disease by juicing cannabis... then gets raided by the government

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Date: November 01, 2017 05:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin C Treatment of Whooping Cough

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Date: July 08, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Organic onions richer in flavonoids

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Date: June 12, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: MedDiet Protects Against Atherosclerotic Plaque

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Date: May 18, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cancer-killing Dandelion Tea Receives $157K Research Grant

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Date: April 29, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Scientists stunned as dried leaves achieve 100% CURE RATE among critically ill MALARIA patients after all pharma drugs failed

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Date: March 24, 2017 02:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 Things to Know About Genetic Testing Bill

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Date: March 15, 2017 08:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Research Proving Cannabis Kills Cancer Cells Safely has been Suppressed Since 1974

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Date: February 14, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What are heart failure, heart attack and cardiac arrest?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3940)

Date: December 13, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Omega-3 intake may aid in recovery of concussions and brain injury

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Date: December 05, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Top Vitamin and Mineral Deficiencies — Are You at Risk? - ProHealth

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3573)

Date: November 14, 2016 10:20 PM
Author: Darrell Miller
Subject: The Health Benefits of Grape Seed Extract

Grape seed extract is most commonly a waste product produced by the grape juice and winery industry. This is because grape seed extract doesn't go into finished drinks. Grape seed contains a wide variety of health-enhancing ingredients like protein, carbohydrates and lipids (healthy fats).

Immune system

Vascular Endothelial Health

High Blood Pressure

High Cholesterol

Pancreas

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3445)

Date: February 21, 2014 05:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Myrrh oil health benefits

Know what Myrrh essential oil is

As you have probably read somewhere else, Myrrh oil is an aromatic resin that comes from trees belonging to the genus commiphora. It has a unique sweet and smoky aroma. Myrrha, hirabol myrrh and bola are other alternative names that people use frequently when referring to myrrh oil. Known to contain cadinene, cuminaldehyde, a-pinene, acetic acid, m-cresol, eugenol and formic acid, this pale yellow oil has been the source of debate due to its many benefits which go back to the time of ancient Egyptians.

Why take myrrh oil?

Modern scientific research has found evidence suggesting that myrrh has a wide range of uses that are beneficial to boost the health condition of an individual. Myrrh is an amazing extract that can be used in aromatherapy to effectively treat colds, coughs, insomnia and sore throat. In the digestive system, the oil is widely used for indigestion and ulcers treatment. Women and young girls find it necessary to increase their menstrual flow using normal remedies but have failed. However, this sap-like oil does not only increase the menstrual flow but it also relieve painful periods and ease difficult labor in childbirth.

For all medical dental infections, the oil is included when mixing a mouthwash. On the skin, it has great success when wiping out bedsores, boils, cracked skin, skin ulcers, athlete's foot and eczema. As a matter of fact, it is sometimes used as an ingredient in many skincare products, creams and lotions.

Myrrh is also purported to treat certain cancers and tumors. The extract from Commiphora trees is highly effective against the gynecologic cancer cells. When used as an anti-oxidant, amazing results are achieved in protecting against lead induced hepatotoxicity.

When can you start taking myrrh resin?

It is recommended to take myrrh essential oil three times in a day or as needed. Pregnant and nursing women should start using it after consulting a qualified practitioner. It can be used as a dietary supplement for children when they reach the age of six years.

Sources

1. //www.essentialoils.co.za/essential-oils/myrrh.htm
2. //www.webmd.com/vitamins-supplements/ingredientmono-570-MYRRH.aspx?activeIngredientId=570&activeIngredientName=MYRRH
3. //altmedicine.about.com/od/aromatherapy/a/Myrrh-Essential-Oil.htm
4. //www.medicalnewstoday.com/articles/267107.php
5. //www.youngliving.com/en_US/products/essential-oils/singles/myrrh-essential-oil
   

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3030)

Date: February 17, 2012 07:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs For Depression: Alternative Solutions To Improve Your Mood

What Herbs Can Help With Depression?

Depression - Introduction:

Depression is brain system disorders that can make many people weaken from functioning normally during episodic events. Some types of depression actually paralyze people and prevent them from leading a normal life.

In addition, it is important for individuals who suffer from depression to realize, that they do not have to hide this condition and think that they suffer alone. In fact, many people have some form of depressive disorder. Something must be done is to take action to reduce their depression treatment.

Depression - Herbs That Can Help Reduce:

Depression and anxiety are very common in the modern world, and there is no single drug offers an effective cure. However, there are many herbal remedies that can help you reduce depression:

1. St John's Wort (Hypericum perforatum).

St Johns Wortis a eternalcompoundwith littleyellow flowers that originally came from Europe, but also widely used intoAmerican. It is used extensively by European physicians to reducedepression. Two compounds, hypericin and hyperforin, give St. John's Wort potencyto keepmood and fight depression. St. John's Wort also contains flavonoids and proanthoclanidin substances that can affect the peace and balance to the nervous system.

2. Valerian.

Valerian is the most popular herbs to relieve nervous tension. Sedative effect was first recognized in the seventeenth century, and since then enjoyed a long history of safe use effectively. Research believe that valerian binds to GABA receptors, which produces lower levels of anxiety. This does not completely eliminate anxiety, just change the way that the brain and your body reacts physiologically and give peace to the nervous system.

3. Kava kava.

Kava kava is a plant found in the Pacific Islands. The roots and bark are usually used as a slurry and then combined with cold water to drink. Due to the active compounds in Kava kava, a chemical known as kavalactone, destroyed by high temperatures, use cold or warm water is very important in its preparation. And studies have suggested a correlation between active ingredients and enhanced mood. To be specific, Kava Kava is estimated to have a relaxing impactand reduce fatigue in the human brain.

4. Ginkgo Biloba.

Ginkgo Biloba is the oldest tree used by China to treat various diseases. In the 1700's it has been introduced in Europe. Ginkgo Biloba is mainly composed of active components such as terpene lactones and flavnonoids, which gives a positive effect on mental well-being. With capabilities that are known to increase blood circulation to the brain, this herb has also decreasethe amount of free radicals in the body and brain, so it appears relaxation that can reduce stress or depression.

5. Lavender Oils.

Lavender is a very popular herbal aroma is mainly due to growing importance as a beautiful and essential oils. The smell of lavender oil can stimulate the nerves that send signals to the brain limbic system, which spur the peace and comfort to the physiological function of human emotional. Lavender has been believed by experts to help relieve anxiety, tension, stress and fear that are part of depression.

6. Lemon Balm.

Lemon Balm serves to inhibit the production of thyroid hormones and can help treat primary or secondary brain diseases and to provide a stimulant for the antioxidant that gives relief to your brain space. Some modern studies have found that lemon balm is useful for promoting sleep quality and reduce the effects of depression tranquility.

7. Chamomile.

Chamomile is a very popular herb in Europe and has been widely used for centuries agoas a treatment for some diseases, such as sleep disorders, stress, anxiety, and depression. Other active compositions including flavonoids and matricinid which gives a feeling of relaxation and regulate the nervous system. Now it has proven to be one of the safest herbs on the market to relieve stress.

Conclusion:

Although the use of herbs for depression is widely spread, overall there is definitely reaction for the benefits of herbs for reduce depression disorders. Apparent when compared with normally drugs for depression that usually can not serve as the first choice of treatment options. However, when other treatments have failed more established, might have to be used.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2582)

Date: February 05, 2012 08:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Benefits of Stevia for Diabetics

No herbal sweetener in the world packs the punch that stevia does. Derived from the plant Stevia rebaudiania, ground stevia leaves have ten to fifteen times the sweetness of sugar, and purified stevia extract has 200-300 times the sweetness of sugar.

Stevia is very popular in many countries, especially among diabetics. Diabetics love stevia for a variety of reasons: its safety, its lack of any effect on blood sugar, the fact that stevia has almost zero calories, the wide variety of products it is included in, and its unique ability to enhance citrus flavors and ice cream.

Unlike artificial sweeteners, stevia is perfectly safe. Stevia has been used in Japan for decades, and the Japanese have very strict standards governing the use of dietary supplements. They have conducted numerous studies on stevia, and no study to date has ever uncovered any harmful effects. Research conducted in the United States and other countries has also failed to find anything hazardous about stevia. In addition, stevia has been consumed for thousands of years in Brazil and Paraguay with no reported negative effects.

Stevia has zero effect on blood sugar. It does not effect insulin secretion in any way, and no diabetic has ever experienced difficulties with stevia. Contrast this with the effects of table sugar and it is clear that stevia is a clear winner.

Unlike table sugar--which is notorious for being calorie laden--stevia contains virtually no calories, which means that no one on a diet has to worry about consuming too much stevia.

There are a wide variety of products available for dieters interested in consuming stevia. Liquid stevia extract is quite popular and can be found in flavors like chocolate, vanilla, peppermint, and more. It is relatively inexpensive, because a little stevia goes a very, very long way.

If you are a diabetic worried about artificial sweeteners but not yet willing to give up diet soda, stevia is the solution to your problem. While usually only available at health food stores and a few supermarket chains, stevia soft drinks exist. If you can find them, you should give them a try, and if you like them, then you can easily subsitute them for the less healthy aspartame diet drinks.

For those interested in ice cream, stevia makes wonderful ice cream. Unlike granulated sugar, which adds a grainy texture to ice cream, stevia adds no irritating textures and leaves ice cream perfectly smooth. If you make your own stevia ice cream you are going to be in for quite a treat, and even more so if you decide to make citrus flavored stevia ice cream.

No one yet understands why stevia enhances citrus flavors, but it undoubtedly does. It is difficult to describe, but stevia has a way of intensifying flavors like lime and lemon in a way that makes those flavors more delicious. Of course, individual tastes vary, but it is generally agreed that stevia lemon sorbet is a treat par excellence.

Don't hesitate to give stevia a try. This ancient herb is the perfect modern solution for diabetics with a sweet tooth.  

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2553)

Date: September 24, 2011 04:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Stress Deplete The Body Of Minerals?

Minerals

Heavy traffic after a long day’s work, trying to sleep and your neighbour’s dog keeps barking and when you wake up in the morning your kids show you their report cards and they failed a couple of subjects then you’re late in getting to work because you had to have that discussion with your kids, you get called off into the boss’ office and he tells you that what you’re doing and the reasons behind it are unacceptable. That’s stress, in the modern world many people believe although there are no conclusive studies about it yet, stress is the number one silent killer in the world.

I mean think about it, aside from the health implications, how many violent acts have been caused by stressed People? Every day in the news you see stressed out people doing things they probably will not do otherwise had they controlled there stress factors. Stress and its health effects though in a more minor scale has been proven to exist like stress induced ulcers or allergies induced by stress so having more detrimental effects to the health is not that far fetch. So in the question of whether the body can be depleted by stress of minerals I would say yes however more than that lets find out how.

Stress and Minerals

Commonly stress is triggered by environmental circumstances which in turn if left unattended can lead to depression however recent studies have come across more evidence that the true culprit maybe a chemical imbalance in the brain. This is where we see that initial relationship between stress and minerals as certain mineral depletion in the body can lead to inefficient functioning of vital organs and one of them is the brain which is where stress just like any other emotion we have originates. In the US, modernisation has depleted our soil of its mineral contents which in turn also affects the food we eat. Aside from food intake, mineral deficiency can also be caused by an underlying heath issue that an individual may have.

From diarrhea to malnutrition the possibilities are wide. Another way that stress has been proven to be related to minerals is in the way it is absorbed. Many studies have shown that some minerals are affected by stress due to inhibiting its absorption in some way. The key for this inhibition property of stress for proper mineral absorption is in the chemicals and hormones it initiates the body to release. When the body is stressed, the normal response for it is to release hormones and chemicals such as adrenaline, noradrenaline and cortisol.

These substances counteract the efficient absorption process that our body otherwise will have if they were in absence. Different minerals maybe affected in different ways but nonetheless affected. Calcium for example will not be absorbed well by the bones in the presence of cortisol and with high adrenaline levels magnesium may be lost through urine and potassium is another mineral that does not react well with cortisol and has marked stress as an inhibitor for its absorption because of this.

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Date: July 01, 2009 12:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Honey from bee's

Bees make honey out of the nectar that they sip from flower blossoms. A long and tedious process is necessary to transform nectar into the thick, golden substance that we call honey. Like each product that is produced by the honeybee, care and a number of steps are essential in order to create this beehive food, with honey being no exception. This sweet, nutritious edible substance is a viscous fluid that is exclusively created by the honeybee. Even the most sophisticated modern techniques have failed to synthetically manufacture honey. Like royal jelly, propolis, and bee pollen, honey is only available from Mother Nature. It is a precious and coveted substance that has fascinated and pleased cultures throughout time.

The ancient Greeks called honey one of nature’s most precious gifts, while the Assyrians, Chinese, and Romans routinely prescribed it for its medicinal value. Numerous biblical references refer to the “Honeycomb” and the “Land of Milk and Honey,” as well as the “Enlightenment” that comes from eating honey. Hippocrates recorded that a honey drink cures phlegm and calms down a cough. He was one of the first known advocates for using Honey and Vinegar for fevers and other ailments. All of ancient cultures believed that the use of honey each and every day would insure health and longevity. All kinds of wines and foods were routinely mixed with honey, causing them to be viewed by all peoples as a treasure which the gods provided for health.

Of all the ancient cultures, Egyptians prized honey enough to use it as a form of money. Hieroglyphics often refer to honey as the universal healer and jars of honey were routinely placed in tombs of the dead. Because of its superior preservative properties, honey used to be an integral part of the formula that was used in the mummification process. Throughout all of history, honey has been used to treat open wounds and fight infection. Unfortunately, the advent of refined sugar caused honey to take a back seat to other more popular sweeteners. Thankfully, today honey is experiencing resurgence, as it was once an often overlooked beehive food that is full of nutritive and medicinal value.

When a bee lands on a flower, it sucks a tiny amount of nectar to its honey sac. It is within this sac that the transformation of nectar to honey begins. The nectar is mixed with acid secretions to eventually form the coveted honey that we consume. Substantial amounts of nectar are necessary to produce significant amounts of honey, making flying the distance of up to three miles necessary to obtain the amounts of nectar that is needed to fill the sac. Once the sac is full, the honeybee returns to the hive, where a receiving bee takes the nectar and continues the process, changing, enriching, and concentrating the nectar. Following this, the receiving bee drops the mixture into the empty cells of the honeycomb.

In order to produce a single pound of honey, bees must provide the hive with over 70,000 loads of nectar. A healthy beehive can produce about 300 pounds of honey each season. The health benefits of honey have now been captured by manufactures like Premier one and Montana big sky. Natural honey is available in liquid form at your local or internet health food store. Look for name brands to ensure quality and purity of the product you purchase.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Honey is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

Fine Honey Products from Premier one are available at VitaNet ®, LLC Health Food Stores.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2027)

Date: June 24, 2009 12:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium, Magnesium And Vitamin D

In February 2006, the findings of an $18 million double-blind placebo-controlled study were published in the New England Journal of Medicine. This study was conducted by the Women’s Health Initiative (WHI) and was on the protective effect of calcium and vitamin D. The New York Times reported on this study, declaring that the study found that there were no clear benefits to calcium pills. In this article, the fact that the women who stuck to their supplementation regime experienced 29% reduction in hip fractures was dismissed. This result is rarely achieved, even with use of the strongest pharmaceuticals.

This study was designed to determine whether postmenopausal women who were given calcium and vitamin D would have a lower risk of hip fracture. The intervention group was given 1,000 mg each day of calcium carbonate, along with 400 IU of vitamin D. Although these women portrayed a greater preservation of hipbone density, the decrease in risk of fracture of 12% was not significant as a whole. The fact that many of the women who were included in the study were under sixty, and therefore, not typically at risk for fractures, causes these results to be unsurprising.

The results that were found were also skewed as a result of the fact that compliance with the prescribed daily intake was only 59% by the end of the study. 41% of the study participants had fully stopped taking the prescribed daily dosage of calcium and vitamin D, with 24% having discontinued the supplementation altogether. With such an unexpectedly low compliance rate, along with the fact that the projected hip fracture rate was over twice what was actually observed, the power of the study was reduce to only 48%. As a result, the trial had less chance than a simple flip of a coin to find anything but the largest of differences in a risk for fracture.

Despite these shortcomings, the researchers looked at the subgroups, and found different pictures emerging. Looking only at the women who mostly stuck to their prescribed regime, researchers found that a reduction in fractures of 29% was experienced. Additionally, those women over sixty experienced a reduction in the risk of fracture of 21%. These results are actually remarkable, especially after considering the many problems which clouded the accuracy of the data. Unfortunately, reporters did not look at these findings, causing a slanted account of the study to be published. Because of this, the media failed to acknowledge what were actually significant findings.

Additionally, the design of the WHI study disregarded the fact that a reduction of fracture risk is actually dependent on several factors other than calcium. Studies have actually shown that magnesium is also of equal important in the treatment and prevention of osteoporosis, as a deficiency plays a central role in the development of the disease. Postmenopausal women and those women with osteoporosis usually have low bone-magnesium content, exhibiting other indicators of magnesium deficiency that are not seen in non-osteoporotic women. Also, calcium competes for absorption with magnesium, meaning that postmenopausal women who increase calcium intake without also increasing magnesium intake can impair their absorption of magnesium. With this knowledge, the failure of the researchers to include magnesium supplementation along with calcium and vitamin D caused the potential for a study that could cause harm on the patients. With the results as they are how can we trust studies that are conducted when the patients who participate do not follow the rules? For those who want to prevent osteoporosis, calcium, magnesium, and vitamin D when taken together can help slow and prevent the onset of brittle bones.

Calcium, magnesium, and vitamin D come in capsule, tablet, and liquid softgel forms at your local or internet health food store. Always look for a name brand calcium, magnesium, and vitamin D supplement to ensure quality and purity of the product you purchase.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2024)

Date: June 09, 2009 12:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: BoneSet For Fevers

Boneset was used by Native Americans for a valuable remedy against colds, flu, and fevers. Other common names that boneset is identified by include: thoroughwort, vegetable antimony, feverwort, agueweed, Indian sage, sweating plant, eupatorium, crossword, thoroughstem, thoroughwax, and wild Isaac. In most cases, boneset has been used primarily to treat fevers. They introduced boneset to the settlers in the New World. From 1820 through 1916, boneset was listed in the U.S. Pharmacopoeia. This herb was also listed in the National Formulary from 1926 through 1950. Boneset has been used to restore strength in the stomach and spleen. It has also been used as a tonic for acute and chronic fevers. Dr. Edward E. Shook actually felt that boneset was beneficial for every kind of fever humans are subjected to. He also believed that it had never failed in overcoming influenza.

Recent research has found that boneset contains antiseptic properties that help to promote sweating. These properties also help in cases of colds and flu. Boneset has also been shown to contain antiviral properties and strengthen the immune system by enhancing the secretion of interferon. Additional studies have found that boneset is effective against minor viral and bacterial infections by stimulating white blood cells. Additionally, this herb has been used to treat indigestion and pain and may also contain some mild anti-inflammatory agents to help with conditions like arthritis.

Boneset is a perennial herb that has an erect stout and a hairy stem. It grows from two to four feet high, with branches at the top. The leaves of the boneset plant are large, opposite, united at the base, and lance-shaped. They grow anywhere between four to eight inches in length and taper into a sharp point. The edges of these leaves are finely toothed, with prominent veins. These leaves help to distinguish this plant species at first glance. The flower heads of the boneset plant are terminal and numerous, being large, and having anywhere from ten to twenty white florets. The plant possesses an aromatic odor, with an astringent and strongly bitter taste. This plant species varies considerably in size, hairiness, form of leaves, and inflorescence. It can typically be found flowering from July to September.

The entire herb is used to provide alterative, anti-inflamamtory, antiperiodic, antiviral, diaphoretic, emetic, febrifuge, purgative, nervine, and stimulant properties. The primary nutrients found in boneset include calcium, magnesium, PABA, potassium, and vitamins C and B-complex. Primarily, boneset has been shown to be extremely helpful in dealing with chills, colds, coughs, fever, flu, malaria, pain, rheumatism, typhoid fever, and yellow fever. Additionally, this herb is beneficial in treating bronchitis, catarrh, jaundice, liver disorders, measles, mumps, Rocky Mountain spotted fever, scarlet fever, sore throat, and worms. For more information on the many beneficial effects provided by boneset, please contact a representative from your local health food store.

Although there is no recent clinical evidence that guides the dosage of boneset, traditional use of the herb suggests that a dose be about two grams of leaves and flowers. The internal use of this herb should be tempered by the occurrence of hepatotoxic pyrrolizidine alkaloids in this plant. For those women who are pregnant or lactating, this herb should not be used, as there have been documented adverse effects on those women who are pregnant and/or lactating.

Boneset is available in capsule, tablet, and liquid extract forms at your local or internet health food store. Look for name brands to ensure quality and purity of the product you purchase.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2015)

Date: December 11, 2008 12:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Inositol And Choline

Inositol is a member of the vitamin B complex family, being referred to as vitamin B8, but is not strictly a vitamin because it is biosynthesized in your body. Vitamins are essential substances that are not manufactured by your natural biochemistry, and must be taken in your diet. However, to all intents and purposes it works like a member of the vitamin B family.

The main function of myo-inositol (the commonest isomer of inositol) is in the health of cell membranes, particularly those that comprise the marrow, eyes, intestines and the brain. Without proper regulation of the cell membrane, the cell cannot function effectively. Some of its effects include healthy hair and controlling estrogen levels. It is also believed to help to reduce cholesterol levels in the blood.

A deficiency will result in hair loss, eczema, increased blood cholesterol levels and eye abnormalities. You might also suffer constipation, although this is not as serious a condition as those preceding. It is present at highest levels in the heart and brain, which indicates where it is mostly used, although it also helps the liver to break down fats and enables the nerves and muscles to operate as they should.

Those that are depressed are frequently found to have low inositol levels in their spinal fluid, so it is believed to play a part in that condition. It is known that the substance takes part in the function of the neurotransmitter serotonin, which is known to play a part in depression, and initial signs are that its use in the treatment of depression could be effective. Neurotransmitters are responsible for passing messages across the gap (synapses) between nerve cells, their messages being decoded by the neuroreceptors. A healthy nervous system depends on healthy neurotransmitters.

For these reasons, inositol has also been tried on other conditions of the nervous system. These include bipolar disorder, bulimia, panic disorder, obsessive compulsive disorder and attention deficit disorder. So far, results have been inconclusive as to its effectiveness, but it is early days yet and field tests are continuing.

A test carried out in Beersheva, Israel, in 1997, found that treatment with inositol produced significant improvement in the depression of 28 patients after four weeks on the Hamilton Depression Scale1, and 21 patients tested with panic disorder (with and without agoraphobia) showed significant improvements in their condition, including agoraphobia. Results on 13 patients with obsessive compulsive disorder also showed significant improvement. These were all double-blind tests.

However, not all tests have been so conclusive, and a study on 42 people with sever depression who did not respond to conventional antidepressant, also failed to respond when inositol was added to their medication.2 Results are therefore not conclusive.

Four hundred people took part in a double-blind test that indicated a possible improvement in the symptoms of polycystic ovary syndrome when treated with inositol 3,4 and another that inositol treatment on patients taking lithium could help reduce the symptoms of psoriasis, a skin condition believed to be caused by a reaction of the immune system and nerves.5

The supplement has also been found to be just as effective as Luvox (fluvoxamine – similar to Prozac) after four weeks treatment. Although these results are good, they are inconclusive, and more data is need before any indisputable conclusions can be drawn. However, treatment with inositol might be worth considering if conventional treatment for these conditions has been unsuccessful.

The most common natural form of inositol is myo-inositol, an isomer of cyclohehexanehexol, a carbocyclic polyol that form the structural basis for secondary messengers in the cells of eukaryotes.

A secondary messenger system is one whereby a signaling molecule is released in response to a signal from a primary messenger such as a neuroreceptor, which then activates certain intracellular proteins known as effector proteins that exert a response from the cell. An example is cAMP (cyclic adenosine monophosphate) that is a secondary messenger that activates protein kinases and allows them to phosphorylated proteins.

Eukaryotes are organisms that contain cells composed of complex components contained within a cellular membrane, and that also contain a nucleus. Examples are fungi, plants and all animals. Examples of non eukaryotes include the bacteria family.

It is frequently recommended that inositol is most effective when taken with an equal amount of choline, although this might be due to the fact that when inositol deficiency is detected, choline is also frequently deficient. Both are vitamin B family like, and both are lipotropic, in that they aid the breakdown of fats in the body. It is not clear whether this is true or not, but taking both would certainly not harm you, and might be of great benefit.

Inositol is not essential, because it can be obtained from beans, nuts, seeds, whole grains, cantaloupe, brewer’s yeast, liver and vegetables. Bacteria in the gut also act on the phytic acid (inositol hexaphosphate) contained in citrus fruits to form inositol.

However, be careful if you drink a lot of coffee. It destroys inositol, and if you are taking the supplement medicinally, steer clear of coffee during your period of treatment because it will lose its effect. Excessive coffee drinking can also result in a general depletion of inositol from your diet, and hence a deficiency. In such a case you are advised to take a supplement, preferably along with choline that might also be deficient.

Although there have been no adverse side effects reported, no specific longer term safety studies have been carried out on inositol. Because of the way it works, inositol should be avoided by people with liver or kidney disease, and also by expectant or nursing women. It should be avoided by young children until safety tests have been carried out, and it is believed that it can cause manic effects in those suffering bipolar disorder.

Other than for these specific cases, trials with many times the average daily intake of the substance, it currently appears safe to take inositol as a long-term supplement. However, as with all such supplements intended for specific disorders, you should seek the advice of your physician.

References: 1. Levine J: Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev,Beersheva, Israel ur Neuropsychopharmacol, 1997 May, 7:2, 147-55

2. Nemets B, Mishory A, Levine J, et al. Inositol addition does not improve depression in SSRI treatment failures. J Neural Transm. 1999;106:795-798.

3. Gerli S, Mignosa M, Di Renzo GC. Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2003;7:151-9.

4. Gerli S, Papaleo E, Ferrari A, et al. Randomized, double-blind, placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS. Eur Rev Med Pharmacol Sci. 2007;11:347-354.

5. Allan SJ, Kavanagh GM, Herd RM, et al. The effect of inositol supplements on the psoriasis of patients taking lithium: arandomized, placebo-controlled trial. Br J Dermatol. 2004;150:966-969.

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Date: December 10, 2008 10:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hoodia Gordonii

Hoodia Gordonii is a South African succulent plant of the family Apocynaceae. They are remarkable similar in appearance to cacti, although they are totally unrelated to them and grow predominantly in the region of Central Namibia in the south west of Africa, up to the southern regions of Angola. They are most commonly found in rocky ground and on the plains.

There are several species of hoodia, some of them grown domestically, and it is Hoodia gordonii that is used as an appetite suppressant in hoodia weight loss pills. Although the plant has historically found use in the treatment of infections and gastric problems, most interest is displayed in its use by the bushmen of the Kalahari Desert to suppress their appetite during long hunting trips when food and water are scarce.

The active ingredient was isolated in 1977, and given the name P57: the product is therefore often referred to as Hoodia P57. It was patented by its discoverers, the CSIR (South African Council for Scientific and Industrial Research) and a license granted to UK company Phytopram, who worked together with Pfizer to isolate the active ingredients and manufacture them synthetically. This was found to be very difficult, if not impossible, since any synthetic form of the extract failed to display any hunger-suppressant properties.

Finally, the rights to the main ingredient were released by Pfizer in 2002, thus indicating that it was of no commercial benefit to them. The main problem they admitted with synthesizing P57 was not only the difficulty in doing so, but also that there were side effects of the extract on the liver caused by other components that could not be removed. No synthetic form of hoodia is therefore available, and only the natural plant is used in current Hoodia 57 preparations.

The rights of the San Bushmen to the plant were recognized by the CSIR in 2002, and not only do they receive a proportion of the profits of marketing hoodia, but also the plant is protected with wild-harvesting licenses provided to only certain individuals and companies. Due to the rising popularity of the hoodia weight loss industry, the plant has been named as an endangered species in the wild.

It is believed that the active ingredients are steroidal saponins that can fool the body into believing it is full. This theory is based upon the effect on appetite of glucose concentrations in the blood. Your appetite is controlled by the amount of unconverted glucose in your blood, and glycogen in the liver. When you eat carbohydrates, they are digested and converted into glucose which is absorbed into the bloodstream.

Under normal conditions your blood glucose levels increase to a level where a signal from hypothalamus stops you feeling hungry. Insulin is then secreted from the pancreas to prepare your cells to use that glucose in the mitochondria to create energy by means of the Kreb's Cycle, or Citric Acid Cycle as it is also known. This reduces the concentration of glucose in the blood, and once it reaches a certain level the body begins to use its emergency energy supply, glycogen, that is stored in the liver.

A signal then informs the brain that more glucose is needed. You then feel hungry again, and this cycle is repeated several times a day in a normally healthy person. This cycle is controlled by certain hormones in the brain, specifically in the ventromedial center of the hypothalamus, where it is believed that the ATP (adenosine triphosphate) availability controls the release of the hormones involved.

ATP is the molecule of energy, and as the concentration of blood glucose and of glycogen drop, then the amount of ATP produced also drops and this is detected in the hypothalamus, which reacts by releasing ghrelin. Increased leptin increases the feeling of satiety and ghrelin increases the feeling of hunger. Serotonin acts on the brain to increase the effect of leptin in the hypothalamus, and therefore make us feel less hungry, or more satiated.

It is believed that hoodia gordonii, or the Hoodia P57 component of it, fools the brain into believing that your blood glucose or glycogen levels have reached the point at which it should trigger a satiated response, so that you stop eating even though your ATP levels might be low. The steroidal saponins that it contains is believed to be ten thousand times more effective than glucose in stimulated the secretion of serotonin.

Hoodia has also been found to contain a number of glycosides, including pregnane glycosides that some studies have indicated to help control appetite of the subjects tested. Most of these tests have been carried out on animals, although Hoodia weight loss preparations are offered in a form standardized on both steroidal saponins and pregnane glycosides.

Hoodia gordonii is becoming so popular as a weight loss product that its export is being monitored by the South African government. It has become so endangered that, since 2005, only hoodia grown on commercial farms is permitted an export license, and exporters must obtain a license from the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Importers also require a permit from the US department of Agriculture, and a CITES certificate is also needed to re-export the finished product.

Because of this, more hoodia weight loss pills are being sold than there is hoodia gordonii to produce them. It is not uncommon for cacti such as the prickly pear cactus from Mexico, to be used, or for low concentrations of hoodia to be bulked up with fillers. Neither of these is of any use as an appetite suppressant, the former having no active ingredients whatsoever and the latter containing only traces.

If you are purchasing hoodia, therefore, be aware of this. Request sight of the CITES certificate and USDA permit, and also the analysis results by an authorized laboratory to confirm that the product is what it purports to be. Otherwise, there is some evidence that Hoodia gordonii can help you reduce weight, although to date there are only four recognized analytical laboratories registered to analyze the active content of hoodia weight loss products.

Finally, check for the analysis certificates. All Hoodia weight loss products should be analyzed by each of three methods: Microscopy, High Performance Thin Layer Chromatography (HPTLC) and High Performance Liquid Chromatography (HPLC) - all there are needed. The four authorized laboratories are: the University of Mississippi, Chromadex labs in Irvine California, Alkemist Pharmaceuticals and Advanced Laboratories, Smithfield, NC.

No others will do, so if your Hoodia weight loss preparation has not been analyzed using the three methods by one of these laboratories, don't buy it, even if it can show the CITES and USDA documentation.

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Date: September 22, 2008 09:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Panax Ginseng

Panax is a type of perennial plant with fleshy roots, and grows in Eastern Asia. Ginsengs contain ginsenosides that are triterpene saponins, steroidal compounds that are found only in Panax ginseng. The effects of these saponins are difficult to establish, but they are believed to be behind the properties of ginseng.

Panax ginseng is found predominantly in Korea, China and Siberia, although a genus has also been found in Vietnam. Panax are adaptogenic herbs that help promote resistance to anxiety, fatigue and stress, and are said to adapt the body to resist a number of different stressors. It has been proposed that adaptogenic herbs can balance the endocrine hormones of the hypothalamus, pituitary and adrenal axis.

They also normalize the immune system, and increase the activity of phagocytes, the killer cells. Additionally, they not only help to maintain homeostasis, but are believed to go further and act as allostatic agents, adapting response to maintain system stability in a more dynamic fashion, by changing interactive functions as opposed to the individual adaption’s made in homeostasis.

Not all ginsengs are the same, and although Siberian ginseng is an adaptogen, it is not a true ginseng. Its roots are woody rather than fleshy, and it contains eleutherosides as opposed to ginsenosides. These also are triterpenoid saponins, but of a different adaptogen. The herb is actually Eleutherococcus senticosus as opposed to Panax ginseng and P. quinquefolius, both true ginsengs. Siberian ginseng was misnamed as a marketing ploy.

American ginseng is Panax quinquefolius, sometimes referred to by the Chinese as Huaqishen. It, too, is an adaptogen and a true ginseng, containing ginsenosides. However, it contains much less ginsenonide Rg1 than panax. This ginsenonide appears to possess estrogen-like activity and improves spatial learning. The other forms of ginesonide found in panax ginseng are:

Ginsenoside Rb1: This appears in greatest concentration in American ginseng, and appears to have an effect on the reproductive system. It not only has an effect on the testicles, but is believed to increase testosterone production through its stimulating effect on luteinizing hormone. It also helps to rdeduce the incidence of angiogenesis, which is the formation of new blood vessels from old, and also a stage in the development of malignant tumors from dormant ones.

Ginsenoside Rc: this possesses sedative properties, and in a study on breast cancer was found to have an effect in inhibiting the growth of these particular cancer cells. Ginsenoside Rc might therefore have use in the treatment or prevention of breast cancer. Studies have also suggested that this ginsenoside could increase the motility of sperm: the motiliy of sperm was found to increase significantly in a solution of ginsenoside Rc.

Ginsenoside Rf: this is present only in panax ginseng, and studies have indicate that it has an inhibitory effect on the Ca2+ neural channels in the brain, and so cokld have an analgesic effect. Studies have as yet failed to explain this effect that is seen in animal tests, but are continuing on this ginsenoside.

Ginsenoside Re: this ginsenoside has strong antioxidant effects and has a significant antidiabetic effect in that is reduces insulin resistance, which is likely why ginseng is taken to treat Type 2 diabetes. Studies are ongoing into the properties of this ginsenoside, and also on the other 10 or more that are known to be present in Panax ginseng. The effects of ginseng are difficult to establish with certainity because they work through so many different pathways and it is difficult to isolate one. More than one ginsenoside, for example, affects the calcium channels in the brain, and it is difficult to determine which does what.

There are fewer ginsenosides in Panax quinquefoilius, and in the USA it is only the panax version that can be traded as simply ‘ginseng’. One of the main problems with all ginsengs is that although it is one of the most studied plants, the majority of the studies have been on animals, and due to this, and the difficulties caused by the multiple pathways described earlier, many of the postulations have not been proved in humans.

However, if the theory as it is know today is taken into consideration along with the traditional uses of ginseng in traditional Indian (ayurvedic), Chinese and Native American medicine, it would be fairly accurate to say that ginseng is useful in helping your body to recover after illness or surgery, and to help you to deal with stress. It has also been proved to lower your blood glucose (sugar) levels, and help in the treatment of Type II diabetes, as already mentioned. There is evidence that it helps to boost your mental performance, memory and might help to slow down the onset of Alzheimer’s disease.

Ginseng can also give a boost to your energy levels, and it is genarally accepted that panax ginseng is more effective than the American version. In traditional medicine, Asian ginseng is said to be warming, and the American variery cooling. Thus Panax ginseng is useful for people recovering from illness and trying to recover their strength, acts as a tonic, stimulant and supports the immune system. In other words it helps the body to get whole again after being depleted.

It should not be used if you get very hot and red, such as with heat stroke, unless you use it in combination with the American version, because these are conditions of high yang and this type of ginseng will increase the yang even further.

American ginseng, on the other hand, is good for those with fevers, hypertension (high blood pressure), and suffereing the effcts of heat. It helps build the yin and reduce the yang, so if you always feel flushed and hot or are hyperactive then go for the American, and if you easily get chilled or find your hands and feet get cold very easily, reach for the Asian ginseng to increase your yang.

You often find ginseng as an ingredient in soft drinks, but the concentration is so low that it has no metabolic or pharmacological effect. The dose to be taken should be as stated on the pack, since there is no specific standardization. It has been noted that the effects can be lost if an excess of ginseng is taken, but generally the herb is safe and if you feel a bit down or lacking in energy, ginseng can work wonders for you.

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Date: May 06, 2008 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Grapefruit Seed Extract

Grapefruit seed extract is regarded as being natural antibiotic that is effective against a broad range of bacterial infections. It has also been used to treat parasitic infections and a range of viral infections as well as having found uses for a wide variety of medical conditions.

So what is it about grapefruit seed that is so special? Most people are acquainted with grapefruit, which as a member of the citrus family of fruits, and not to be confused with grapes which are a totally different type of plant. Grape seed extract is also a useful natural medication, but used for totally different conditions.

Because of its efficacy against parasitic and viral infections, grapefruit seed extract is very useful in treating various forms of food poisoning. But, how was this remarkable property of the simple grapefruit seed noticed? The answer to that depends very much upon what version of the story of Einstein Laureate physicist and immunologist Dr. Jacob Harich you believe.

Dr. Harich was not only a scientist but a hobby gardener in Florida, and the two versions of his story tell either that he decided to investigate why grapefruit seeds tasted so bitter, or why the grapefruit seeds in his compost heap failed to compost, or rot. Whichever story is correct, and perhaps both are, the result was the discovery that grapefruit seeds appeared to be a very effective antibiotic.

In fact it has been shown to be effective against over 800 strains of bacteria and viruses and also effective against many fungi that lead to illness in humans. Because of this it is used in cased of food poisoning that involve bacterial infection of the gastrointestinal tract. In fact during the latter part of the 1980s, grapefruit seed extract was tested against a number of known antibiotics and found to be as effective as any of them. Similar results obtained in a number of tests in the USA and elsewhere in the world, and it appears that it is an excellent treatment for the symptoms of food poisoning.

Not only that, but it has been found effective in the treatment of some immunodeficiency diseases, presumably because its antimicrobial properties does much of the work that the immune system would normally do, and so relieves it of much of its hard work. This allows the immune system to concentrate on conditions which are exacerbated by deficiencies in its operation.

Bifidobacteria and Loactobacilli are bacteria that are beneficial to the digestive system. The measure of a good broad spectrum antibiotic is that it does not affect the beneficial bacteria, and grapefruit seed extract has no effect on the former and only a mildly inhibiting effect on the latter. It is also non toxic to humans, which is another measure of a good antibiotic. You would have to drink about two pints of the extract, around 4000 time the normal dose, for the treatment to be potentially fatal.

Among the many uses of the extract are not only in controlling gastrointestinal infections, but also general fungal conditions of the skin, vaginal infections and yeast infections, and also colds and sore throats. It is also believed to support the immune system, not only by its antimicrobial properties but through its effect on intestinal health upon which much of our immune system is dependent. It can also protect patients with symptoms of AIDs and other immunodeficiency conditions from infection.

Its effect on yeast infections around the nether regions of small children has been documented, and it has also been found to be very safe to young children. In fact many mothers have it as a permanent addition to their medicine cabinet.

It is not that long ago when doctors believed all diseases to be due to bacteria or viruses. It is now becoming clear that a large proportion is actually due to fungal infections and parasites. Many conditions such as allergies, circulatory disease and some forms of arthritis have been shown to be due to fungal infections that weaken the immune system. Grapefruit seed extract has been found to be effective in treating many types of fungal disease.

In using the extract in this way, and to treat bacterial infections, it is best to start with a low dose and gradually increase it. This is because when fungi and bacteria are destroyed they release toxins, and too high a dose could result in too much toxin being produced for your body to handle. If you take it gradually you will get the same result, but without the risk of the nausea and diarrhea which the toxins can cause.

Despite all of these benefits, grapefruit extract has not been given the credit it deserves, and much research has still to be done to establish the constituents of the seed that confer these properties. Among these are known to be proanthocyanadins, a class of flavanols with strong antioxidant properties, and a diphenol hydroxybenzene complex that destroys bacteria through the cytoplasmic membrane to prevent the uptake of amino acids and cause leakage of the cell contents. Other active components are Vitamins C and E, tocopherols, limonoids and sterols, in addition to a number of important minerals.

However, there is still much work to be done, although the extract will continue to be used by many devotees for the treatment, not only of food poisoning symptoms, but also of conditions such as acne, athlete’s foot, gingivitis, cold sores, sinusitis and parasitic infections. It appears to be practically a cure-all.

There appear to be no drug interactions, although some medications do react with grapefruit juice, such as some treatments for high blood pressure. If your treatment advises you not to take grapefruit juice, then do not take grapefruit seed extract. Another factor to be aware of is that since the extract is an effective bactericide, then it could deplete the digestive tract of friendly bacteria essential for digestion. You are advised, therefore, to take a supplement of acidophilus, which is easily taken in the form of yoghurt type drinks specifically formulated or dietary supplement for the purpose.

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Date: January 02, 2008 02:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Big Pharma Plays God, Stealing and Altering Pant Compounds making Synthetic Drugs

It has been claimed by the Nutritional Health Alliance (NHA) that the pharmaceutical companies are formulating their pharma drugs using natural plant-derived substances. This is not totally groundbreaking news, of course, since the whole pharmaceutical industry was based on natural products such as aspirin, derived from willow bark, and antibiotics derived from the penicillin mold.

While there is nothing wrong with them doing this, there are signs of their increasing lobbying to limit the supply of supplements so that Big Pharma can monopolize the production and supply of all supplements and remedies, natural or synthetic. What is disturbing is that bills such as the Adverse Event Reporting Bill, passed by Congress in February 2007 as the Dietary Supplement and Nonprescription Drug Consumer Protection Act, could conceivably place greater powers into the hands of the large pharmaceutical companies to restrict the sales of natural products that are not part of their ‘approved’ prescription range.

This Act requires users and distributors of over the counter and non-prescriptive natural remedies to report any adverse effects that they believe have been caused by the remedy they are using. What this does is to require untrained people to make medical decisions as to what is causing their adverse reaction.

A patient taking several prescription drugs and a vitamin supplement might naturally assume that it is the vitamin that is causing their reaction, since they will believe the drugs to be safe. Hence they will report the vitamin supplement as being the cause. Since the act does not oblige them to report reactions from prescription drugs, then this opens the door for Big Pharma to hijack plant compounds, and then alter them to make synthetic drugs.

The position of the FDA in all of this is dubious since that body has already made many decisions that favor the large pharma companies rather than the consumer, or producers of herbal remedies.

However, there is also the opposite view that the supplement industry is unregulated, and some degree of control is long overdue. While it is difficult to argue against this, it is the form of control that is in question and also the reasons behind it.

The pharmaceutical companies have long gained through America’s ill health, and it is to their advantage for Americans to become ill or suffer from the chronic diseases that come with a sedentary lifestyle and a diet of fast foods. The industry’s short-sighted approach has been to wait until people become ill and then treated them with expensive drug, rather than prevention that would ultimate lose them customers for their products.

A happy and healthy community, regularly taking supplements that keep them fit and well, is not to the advantage of pharmaceutical companies that prefer a depressed, unfit and sick American population to which they can sell their products. Hence the smear campaigns in the press regarding ‘uncontrolled’ natural remedies, untold bills in Congress, and what could end up as the ultimate revocation of our freedom to consume the natural products of our choice.

If we are taking two or three prescription drugs for a heart condition or to reduce the cholesterol levels in our body, and also an Omega-3 fatty acids capsule, we are urged to report the capsule if we have any side effects from the cocktail. Presumably on the basis that the drugs have been approved by the FDA, and so cannot possibly cause any side effects in us. A fish oil capsule is hardly likely to cause a heart attack, but many prescription drugs can if badly prescribed. However, it is the capsule that is likely to be fingered, banned and then included in a pharmaceutical product that is cleared by the FDA.

Those that take over the counter supplements, vitamins and herbal remedies are a threat and it is difficult not to become cynical about the intentions of such Acts of Congress and the people behind them. True, the supplement and herbal industry probably does require some form of regulation, but to phrase this in such a way as to require medically untrained people to report what they perceive as being the adverse effects of supplements rings of an intention to regulate by restriction or even banning.

When that occurs, Big Pharma will take these products and fashion them into expensive prescriptive drugs that are then approved for use by the FDA. What we were at one time able to purchase from our local health store we would now have to purchase at several times the price through prescription.

The health benefits of natural nutritional supplements are well documented, and the industry are now using methods to ensure standardization of the active ingredients where possible. However, this is not always possible with foodstuffs that do not always grow in standardized ways.

The Dietary Supplement Health and Education Act (DSHEA) was passed by Congress in 1994 to protect and preserve our rights to healthy supplementation of our diets with natural products of our choice. The FDA has systematically failed to enforce this and prosecute synthetic manufacturers who have not kept to the law. The FDA does not need new powers, but the funding to implement those already in existence.

Lobbying in Congress by interested parties should not be allowed to undermine the rights of all Americans of the freedom to consume the products that will provide them with a healthier lifestyle. The DHSEA is all that is needed to preserve this and to protect consumers from Big Pharma and their need to create conditions conducive to an increasing need for their products.

Yes, the health supplements industry likely needs some form of regulation to ensure standardization of products as far as is possible, but the way to do this is not to place medical decisions into the hands of the untrained. Do not forget that these are natural products, available freely from nature in fruit, vegetable and animal products, and are not synthesized in a laboratory as many of today’s drugs are.

However, give them a free rein, and Big Pharma will hijack these natural products, change them and then sell them to us at highly inflated prices to do the job that already do for us: keep us healthy.

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Date: November 14, 2007 12:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Milk Thistle May Help With Cirrhosis, Gallstones, and Hepatitis Liver Problems

Milk thistle, botanically Silybum Adans, is a member of the daisy family that is native to the Mediterranean, the Middle East and North Africa but has also been introduced to California and parts of the eastern side of the USA, and can help with problems such as cirrhosis, gallstones and hepatitis. Although it has been recorded as being used in medieval times as a tonic for the liver, it is only relatively recently that its chemical components have been investigated. Analysis indicated the presence of hitherto unknown flavonoids which were given the name of silymarin. In general, flavonoids are strong antioxidants found in many fruits and vegetables that eat up the free radicals that cause so much damage to our bodies.

Free radicals are very unstable molecules that are generated through pollution, such as smoking, car fumes, perticides etc, and that destroy body cells accelerating aging. They also oxidise the low density lipids (LDL) that carry water-insoluble cholesterol through the blood to the arteries where it is needed to repair damage, resulting in excess deposition and the atherosclerosis that can cause strokes and heart disease.

Antioxidants mop these up like a sponge, and are some of the healthiest types of molecules that we can consume. The silymarin group of flavonoids are particularly attracted to the liver where they act as antihepatoxic agents that prevent the liver from becoming poisoned. But why should the liver be poisoned I can hear you ask, and what are the poisons involved? Can we avoid them? It is a very relevant question, and one that will make you wonder, every time you leave your home, especially if you live in a big city or an industrialized area.

Smoking cigarettes, working with volatile organic compounds that you can breathe in, such as paint and printing ink solvents, the exhaust fumes of cars and diesel engines, factory chimneys belching out tons of smoke, analgesics such as paracetamol, pesticides on your fruit and vegetables that you have failed to wash off, alcohol, etc, etc, etc…

All of these have to be removed from your body or you will die, awash with all these poisons that you have ingested, some deliberately and some not. The organ that does this is your liver: the powerhouse chemical plant of your body that carries out millions of biochemical reactions every day. Your liver converts all of these poisons into molecules that can be flushed away through your body naturally. However it places great stresses upon it, and even your liver needs a rest sometimes, or even just a little rejuvenating tonic would keep it happy.

Milk thistle has been used for just that purpose, especially when the liver has been toxified with excess alcohol, pesticide poisoning or even hepatitis. The silymarin initially coats the cells of the liver by binding to the cell membranes of the cell walls, so that the toxins are hindered from entering the cells. Its antioxidant properties then neutralise any free radicals present that are causing the damage to the liver cells.

It also helps to stimulate the production of proteins to help the healing process, and reduces the fibrosis that is the development of fibrous masses outside the liver cells caused by damaged cells excreting materials such as collagens outside the cells into the general body of the liver. Finally, milk thistle helps to prevent the activity of the immune system in causing inflammation of the damaged cells.

Silymarin acts very specifically on the liver, and is often used by physicians in the treatment of such liver conditions as jaundice, hepatitis, liver cancer and cirrhosis. In addition to its own effects it appears that it stimulates the production of glutathione that is also a very powerful natural tripeptide antioxidant produced by the body when it is under oxidative stress. Its effect on cancer and some diseases is not curative, but to allow the liver to continue to detoxify the body when otherwise it might fail and lead to toxicity problems from which the patient might not be able to recover.

Due to the remarkable regenerative powers of the liver, milk thistle is able to stimulate it into repairing its damage and grow fresh cells to replace the damaged ones. This is the reason for its effectiveness in otherwise very serious degenerative diseases. It is often prescribed by doctors for patients who are taking a number of different medications. Which help the liver to metabolize these medications, since without it, it might struggle to provide the true efficacy of the prescribed drugs.

So far we have been concentrating on the liver, but milk thistle has other properties not connected directly with the hepatic function. It can help to promote the production of bile in the gall bladder and so give the digestive system a boost when needed, where it also acts as a mild laxative. However, it can also help patients suffering from both lose stools and constipation due its effect. It can also help to relieve gallstones, though medical tests are generally carried out first to ensure that they are not too large for the milk thistle to handle.

It is also an anti-inflammatory, and is useful in the treatment of acne and other inflammatory responses, and also for inflammations in the gall bladder, kidney and bladder. There are few serious side effects, although, as milk thistle rids the body of toxins, these toxins can cause problems such as diarrhea, headaches and abdominal pain. Keep in mind that you are releasing poisons from the liver into your system so that they can be expelled by the usual means, and they will put up a fight along the way. However, the milk thistle will usually win in the end.

There currently appear to be no long term issues with taking milk thistle as a supplement over a long period, and it is good way to maintain a healthy liver. Keep in mind that the liver is the body’s chemical plant, where most of the biochemical reactions of life take place, and without we cannot survive. It makes sense, therefore, to look after your liver, and milk thistle is one way of doing that; some would say the best way.

So remember that, although milk thistle may help with cirrhosis, gallstones and hepatitis liver problems, you should be prepared for a short struggle before it wins the day. Always consult your family physician for a clear diagnosis before self prescribing herbs as treatment. Your physician can advise you as the correct course of action to take once diagnosed with a liver blood test first. But, to boost overall health and wellness milk thistle is a great herbal supplement to take on a daily basis.

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Date: November 10, 2007 12:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Keto, The Next Dhea With No Side Effects

7-Keto is a natural derivative of DHEA that is claimed to be free from many of the side-effects of regular DHEA supplements. DHEA is dehydroepiandosterone, which is the most abundantly produced of the adrenal hormones. After production in and release into the bloodstream by the adrenal glands that are situated just over the kidneys, DHEA undergoes metabolism to the male androgen hormones, and the female estrogens.

As you age, the production DHEA declines, starting at about 30, with a 50% decline by time you reach 40 and almost 85% at 70. This is true of the levels of many hormones in the body, though some, like the steroidal aldosterone, remain constant throughout life. The general rate of metabolism also reduces with age resulting in an even lower conversion rate of DHEA to the male and female hormones.

At the same time as this occurs, there also occurs a significant reduction in the biosynthesis of protein in the body, which results in a loss of muscle mass as you age, and also in the regeneration of bone tissue that results in what is commonly termed age-related osteoporosis. Brain cells die at an increasing rate leading to many neurological conditions and the immune system is also affected negatively.

Due to the concurrence of these aging effects, many scientists have related the general hormonal decline with the other effects of aging. The have asserted that if these hormones were restored, than many of the effects of aging could be delayed. Osteoporosis would be delayed due to the body’ s increased ability to restore lost bone mass, the metabolic rate would improve and fat would be burned at a faster rate and continue to build muscle, the brain would lose its functionality at a significantly lower rate and the immune system would continue to protect the body against disease.

In other words we might be able to live longer, but if not that then at least the quality of life would be maintained longer as we aged. This is a very welcome and desirable situation, but the taking of hormones as supplements has long been regarded as fraught with danger due to the possibility of undesirable side effects, some of them potentially very serious. DHEA was considered as one of these hormones that could be used as a supplement to achieve positive results in reducing these age-related changes because it exhibited these effects in tests on animals.

However, in order that a specific substance can be declared responsible for any metabolic improvement that involves liver biochemistry, some form of receptor has to be identified, and this failed to materialize in DHEA. There appears to be no such DHEA receptor, although that does not necessarily imply that DHEA is not responsible in some way. It might very well be a DHEA metabolite that is responsible, and that has still to be identified. It is certainly true that DHEA administered to both animal and human subjects has resulted in an increase in the testosterone and estrogen levels of the subjects. Such an increase is not desirable due to a number of potential side effects as previously inferred.

These are particularly liable to occur with people who already have an adequate level of natural DHEA production within their body. The side effects include acne, irregularity in the menstrual cycle, itchy scalp, increased body odor and an excess of androgenic hormones can lead to hair loss, or male pattern baldness. Interruptions in the heart rhythm, or palpitations, are another very serious side effect of DHEA supplementation, and high doses over a long period introduce a theoretical risk of certain cancers.

However, the discovery of 7-Keto, a natural derivative of DHEA claimed to be free from many of these side effects, has altered the situation. 7-Keto is a powerful antioxidant that speeds up the metabolism of fat and helps to reduce body weight. It also helps to replace lost fat with muscle mass, though it must be stated that this effect is only valid after the natural production of DHEA has slowed down. It is not a body-building supplement.

It was Professor Henry Lardy, of the Department of Biochemistry at the University of Wisconsin, who tested over 150 DHEA metabolites over 10 years and identified 7-oxo-dehydroepiandrosterone as having the greatest biochemical effect without having any detectable side effects. This material was trademarked 7-KETO by the Humanetics Corporation, and one of its known effects is to burn fat quicker by stimulating thermogenesis. It had also been shown to strengthen the immune system and to improve the memory. All of this without any measurable increase in any of the sex hormones. It was released after a careful and intensive series of safety tests on both humans and animals found it safe for human consumption.

It should be stressed that 7-Keto is not a hormone, and is not chemically the same as DHEA: it is a different chemical altogether that is produce when DHEA degrades in the body. Because of this it can be promoted as a non-androgenic or estrogenic form of DHEA. It is thought that all of the conditions that decline as we age that can benefit from a supplement of DHEA, will also benefit from a supplement of 7-Keto. However supplementation is only required from the ages of 25 – 30, when the natural amount of DHEA and 7-Keto in the body start to decline.

It causes neither high blood pressure nor any form of cancer, and was submitted to the FDA prior to being made publicly available. It is important to stress that the substance is neither a steroid nor does it metabolize to steroidal hormones, and is also not a sex hormone. It also has no effect on the body’s sex hormones. The whole point of 7-Keto is that it has the effect of DHEA without having any connection whatsoever with steroidal hormones or any hormonal substances. It is totally innocuous and safe to use, without the risk of heart palpitations, lost hair or any of the other side effects of DHEA.

Without a doubt, 7-Keto is a DHEA substitute that has none of the side effects of its precursor. So if you are over the age of 30 and feel the need for an energy boost, give 7-keto a try.

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7 keto DHEA Sale

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Date: November 02, 2007 03:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3 Relieves Depression in Some Individuals

Omega-3 oils contain fatty acids that are known as essential fatty acids because they cannot be manufactured in your body but have to be taken in your diet. They provide many benefits to your body, and are also believed to relieve depression in some individuals. First, however, an overview of the more conventional benefits of omega-3 oils.

Obtainable in your diet from oily fish such as mackerel, herring, salmon and the like, omega-3 fatty acids play an important part in your normal growth and development, and are also crucial to normal brain function. They can reduce inflammation and protect you from heart disease and some cancers. Studies have shown the fatty acids to be particularly concentrated in the brain and to be important for cognitive processes and memory.

The effects of omega 3 fish oils on the brain are well documented, and they are known to be effective treatments in some cases of bipolar and schizophrenia. It is believed that they could also be used as a treatment in other disorders such as attention deficit disorder and dyslexia, but there is as yet no evidence that this is the case.

Omega-3 fatty acids reduce the so-called ‘bad’ low density lipoprotein (LDL) cholesterol levels and increase the high density lipoproteins (HDL) that take the cholesterol back to the liver for destruction. The end result is a reduction in the cholesterol content of the blood that can be deposited on the artery walls and promote atherosclerosis. Diets high in omega-3 fatty acids appear to lower blood pressure in those suffering from hypertension, and so reduce their chances of heart attacks and strokes.

Omega 3 oils are also natural inflammatories, and help prevent conditions involving inflammation such as arthritis, asthma and menstrual cramps. They appear to help the immune system to fight these conditions and reduce the inflammation and its causes.

They are also important in the formation of prostaglandins that are responsible for the regulation of important functions such as blood pressure, blood clotting and immune response. They are hormone-like substances and also control the synthesis in the body of other hormones. If the balance of fatty acids in the diet is not right, then the subsequent imbalance in prostaglandin and hormone production can lead to disease.

It is in its effect on depression and mood, however, that has surprised many in the medical, profession. Ethyl-eicosapentaenoate, known as ethyl EPA, is a constituent of omega-3 fish oil and many studies have demonstrated that this substance helps cases of depression and related disorders. However, are people justified in turning to ethyl EPA to help them be cured of this condition?

In one study involving 20 people, six out of ten people given the supplement displayed significantly reduced symptoms of depression after four weeks. The effects were noticed as early as two weeks and many of the depression symptoms, such as worthlessness and insomnia, had improved after three weeks. This conformed with the results of many other studies that have been carried out world wide. In Scotland, a number of patients were studied who had failed to respond to traditional antidepressant drugs. Of the seventy patients involved in the trial, all of the patients who were treated with EPA displayed significant improvements in all the symptoms of their depression after four weeks whereas those with the placebo showed no improvement.

Of the two main components of omega-3 fish oil, EPA and docosahexaenoic acid (DHA), only the EPA has this property, and the EPA works best alone when the DHA has been extracted. Studies and tests have indicated that the DHA appears to be important for the brain’s structure, but the EPA for its function, hence the reason for the ineffectiveness of the former in relieving depression which is a function of the brain rather connected to its structure. In fact, depressed people have been found to be deficient in EPA in comparison to those not suffering from the condition. The original idea for this originated with the late Dr. Horribin who was pioneer in researching the effects of lipids on the biochemistry of the brain as far back as the 1970s. Since then the world-wide research has confirmed his theory. However, the reason why this theory works in practice is not yet understood. It has been established that a diet rich in trans fats can unfavorably affect the hormones in the brain that stabilize mood, possibly due to the fats slowing down the system of messaging within the brain. This kind of effect can cause depression.

This is likely due to the slowing down of the messages passing between the synapses. Brain cells communicate by means of chemicals that cross the synapses, or small gaps between the individual cells. They are not directly connected like normal electrical circuits. It has been theorized that the EPA speeds up the passage of these messages between neurotransmitters and neuroreceptors. Other theories have also been promoted, such as that the EPA has properties of its own that cure depression by another route altogether.

A possible clue could be in the findings of one study on a man aged 21 years old whose brain was scanned before and after EPA treatment. The result showed in increase in the mass of brain cells after the treatment. This was contrary to the belief that brain cells could neither be generated nor grown once a person reaches maturity.

An individual suffering depression who would like to treat themselves with EPA would have to buy a lot of oily fish since high doses are needed for this level of therapy. However, it is found in high concentrations in a few supplements available on the market, and when choosing you must use the highest grade of EPA you can get, with as low a DHA content as you can find.

There is little doubt now; however, that the EPA content of omega-3 relieves depression in some individuals, although more work is needed to prove without doubt that it is effective with all forms of depression.

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Omega-3 Sale

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Date: October 25, 2007 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Artemisinin For Better Health And Wellness

Artemisinin, also called Ching-hao-su is a herbal medicine extracted from the sweet wormwood herb, also known as the Artemisia annua. Asians have been using the leaf for centuries to cure simple ailments such as colds and parasitic infections, but it has recently become big business for its effect on malaria.

Sweet wormwood is predominantly a Chinese herb, used for over a thousand years for treatment of a large variety of conditions including malaria. It has also been used to treat wound and skin diseases, and has been recorded as far back as 200 BC as a component of Chinese prescriptions for specific illnesses.

Although the origins of sweet wormwood are in Asia however, it is now grown throughout the temperate regions of the world, and reaches its best in midsummer. Although best known today for its use in treating malaria, its medical uses include treating bronchitis, fevers and general feelings of malaise. It is primarily grown now for the supplement industry and as a non-prescriptive natural cure for malaria. It is a common and favorite herb for Chinese herbalists and sold both in the herbal form and as the extracted artemisinin.

Although there is a wide variation in the artemisinin content of sweet wormwood according to where it is grown, and under different agricultural conditions, it is the main active ingredient. Chemically, it is a sesquiterpene lactone containing an endoperoxide bridge that will be discussed later.

In order to attain the optimum yield of active artemisinin, the plant has to be grown in the right site for cultivation and fed with the correct fertilizers, the proper strain of the herb must be selected and the method of extracting the active chemicals is also critical. These are secrets that have been used for centuries by the Chinese herbalists who are masters of their craft and are now known to the west and being applied to scientific production of the extract.

There are benefits of artemisinin other than its effect on malaria, but that is the best known of its uses, so let’s have a look at that first. The herb has been used for a long time to treat parasitic infections, mainly flukes and worms that place great strains on the body having not only to feed these unwanted creatures, but also to excrete their waste and by-products. Malaria is caused by such a parasite, any one of four types in fact, and artemisinin appears to be just as effective on them.

The chemical contains what is known as an endoperoxide bridge that reacts with iron. The product of this reaction is a free radical, normally unwelcome in the body. However, malaria parasites contain high levels of iron, and the artemisinin reacts with that iron, forming free radicals that then go on to kill off the parasite. The free radicals that we take supplements to destroy, actually work for us in the destruction of the parasite that cause malaria. There is a silver lining in every cloud!

The reason that the medical world is so excited with this material is that malaria is second only to tuberculosis in its impact on world health. The problem is that the parasites that cause it have become largely resistant to the normal cures. They are not, however, resistant to the endoperoxide chemistry contained by artemisinin. It is now the major hope of world leaders in the fight to stop the inexorable increase in deaths due to malaria.

Now for the other applications. Another major use of the chemical is in the fight against cancer. Those cancers that involve iron rich cells can be disrupted by artemisinin by the same mechanism that kills off malaria bacteria. It is not only parasites that are susceptible to free radical action, but also human cells, and if these can be selectively destroyed, then it is a step forward towards a cure for cancer. Such a cure does not yet exist, but mechanisms such as the endoperoxide bridge provide a means of controlling at least some cancers, the best results being obtained with leukemia and colon cancer. That is not to say, however, that cures for these cancers are currently available since tests are still under way. However, it would do no harm to use sweet wormwood or the artemisinin extract as a supplement.

Cancer cells tend to accumulate iron because it is needed in the cell division process that cancer takes advantage of. However, if cancer cells could be persuaded to accumulate more surface iron, or were artificially exposed to it, then perhaps the endoperoxide mechanism would be more effective. Studies on this mechanism of controlling cancer are currently under way.

At a more mundane level, if you suffer from intestinal parasites, then one or two milligrams each day should see them off. It has also been effectively used to deal with colds, coughs and other general conditions, but most effectively against those that cause fever of one kind or another. It has been used in Chinese medicine as a form of ‘cure-all’ to be used when specific remedies failed. Its greatest current uses are, however, in cancer and especially malarial treatments.

You have to be careful with artemisinin since it can be toxic if taken in the wrong form. The least toxic, and most active, is the water soluble form known as artesunate. However, it lasts the least time in the body and has to get to work quickly. The oil soluble form, artemether, is the most toxic, but can cross from the blood to the brain. However, the parent form, artemisinin is the very safe itself, and can also cross the blood-brain barrier and while some tend to use a combination of the three, others prefer just the parent form.

If you take too high a dose you can suffer neurotoxicity which makes you wobble when you walk, and makes you impervious to certain levels of pain. However, such doses are next to impossible accidentally, and there have been very few reports of adverse effects in humans. It should not be used for at least a month after you have had radiation therapy because that tends to release iron that can be attacked to form free radicals. The recommended dose is 200 – 100 mg daily though the doses should be spread throughout the day. It should also never be taken within 2 hours of any other antioxidant such as vitamins A, C and E. Otherwise artemisinin can be safely used for better health and wellness in the way that the Chinese have been using it for centuries. Artemisinin is available at your local or internet vitamin store.

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Date: October 14, 2007 05:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pumpkin Seed Oil is good for your health

Pumpkin seed oil, as the name suggests, is obtained from pumpkin seeds, which can also be eaten roasted in the same way that people eat sunflower seeds. When roasted, they are coated in a sauce such as Worcester sauce and then heated in low oven for a long period of time. The secret of roasting them to maintain their nutritional value is to keep the temperature low and the cooking time high.

The seeds are regarded as a ‘superfood’ that is rich in vitamins A and E, the essential fatty acids known as Omega 3 and Omega 6, zinc, iron, magnesium and potassium. The seed is known as a pepita in North and South America.

The oil is reddish green and many people find it delicious. It is best when used raw, and can be drunk in the form of smoothies or shakes, or used as a salad dressing. Some also enjoy drinking it raw, and using it as a spread instead of butter or margarine. The benefits it provides to the human body are a healthy brain function, increased energy and it has a special use in maintaining a healthy prostate gland.

The vitamin E content is high, especially gamma-tocopherol, and it has a high antioxidant effect with consequent anti-inflammatory properties. Its effect on arthritis, and inflammatory disease, has been investigated and the inclusion of pumpkin seeds in the diet has been found to reduce the inflammatory symptoms of the condition with a consequent reduction in pain. In fact, in a comparison test with indomethacin, a common arthritis treatment, pumpkin seeds compared very well and in fact had a more positive effect on the damage to the fats in the joint linings than did indomethacin, which tends to increase the concentration of lipid peroxides rather than reduce them.

Its effect on the prostate gland is partially due to its high zinc content that is present in a higher concentration in the prostate than in any other gland in the body, and also to its effect on the hormones that cause the gland to grow and swell to the extent that it constricts or completely blocks the urethra, the tube connecting the bladder to the outside of the body. This is caused by an enzyme that converts testosterone to dihydrotestosterone (DHT). DHT causes the over-proliferation of the prostate cells.

The reason for the effect of pumpkin seed oil on DHT is still under discussion, but some believe that it is connected with the zinc content and others with the high level of delta-7-sterine in the seed. The sterine appears to neutralize the effect of the DHt on the growth of prostate cells.

In addition to prostate enlargement, Osteoporosis is another problem associated with aging in men. It has been estimated that men over 50 have a 12.5% chance of suffering a fracture due to brittle bones, and it is though that this is connected with a deficiency of zinc. In fact a clear correlation has been established between osteoporosis in older men and low levels of zinc and the diet and in the blood. Pumpkins seeds, as already mentioned, are rich in zinc, and the benefits of their use as a supplement to avoid an enlarged prostate is reinforced by their effect in protecting against osteoporosis.

Pumpkin seeds contain a high concentration of the antioxidants lutein and zeaxanthin. These are specifically useful in protecting the cardiovascular system and prevent atherosclerosis. They also contain plant sterols known as phytosterols that are believed to help reduce the blood concentration of cholesterol. This types of sterols are the basis of the ‘cholesterol busting’ drinks that are sold in supermarkets. They also help to strengthen the immune system and are believe to help reduce the risk of contracting some types of cancer.

Pumpkin seed oil is a rich source of alpha-linolenic acid, an important unsaturated fatty acid that some studies have indicated can be used to prevent metastaes (the spread of the disease) development in patients with breast cancer. The most prized type of oil is that from Syrian oil, from the province of Steiermark in Austria. Such pumpkins are also grown in parts of North America, and the best oil is said to come from the first pressing, the so-called ‘virgin’ oil. If used in cooking, the temperature must be kept low, since many of the nutrients are destroyed much over 100 Celsius.

A little known use for pumpkin seed oil is in eradicating intestinal parasites. Many people are embarrassed at requesting professional help for worms, and pumpkin seeds are the ideal home remedy. The act almost immediately, and two or three hours after taking them, or the oil, then you should take a laxative. You should the parasites being removed with the bowel motions.

The worms are not actually killed, but are paralyzed, and cannot prevent themselves being removed with the bowel movement. If a laxative is not taken, however, they will recover and there will be no effect. As with any remedy for a health condition, therefore, it is necessary to understand how the seeds or oil work to help to remove the horrible parasites from your body. They are very common, and any self-help or natural remedy that actually works will undoubtedly be very popular, but if it is not understood that these creatures must be expelled from your body while paralyzed, then pumpkin seeds or oil will not work.

Those that failed to understand the process would then complain that the treatment does not work. In fact, it does work, and if the worms are expelled when they are unable to remain in your intestines then they will be removed. You must “read the instructions on the bottle” for the contents to work.

Pumpkin seed oil is a very potent mixture of chemicals that can cure or control a large number of conditions, and it is essential that you understand why you are using them. They can be used as a supplement to your diet, though it is easy to wonder why you should take this antioxidant rather than another.

Find out what pumpkin seed oil can do for you, and if it applies to you then use it. There are stronger antioxidants, and better foods to take in an attempt to protect from certain conditions. However, there are certain circumstances when pumpkin seeds will do the job better than most other supplements, and if you can fit them into your regular diet then they will not only do you ‘no harm’, as they say, but will do you a great deal of good. Look for organic pumpkin seeds or pumpkin seed oil at your local health food store.

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Date: January 25, 2006 04:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B Vitamins Avert Stroke, Coronary Disease, Death

B Vitamins Avert Stroke, Coronary Disease, Death

London, Ontario--Taking B Vitamins may lower homocysteine levels, thereby reducing the risk of ischemic stroke, coronary disease and death, according to an efficacy analysis of the Vitamin Intervention for Stroke Prevention trial (VISP).

Published in Stroke (36, 11:2404-09, 2005) (//stroke.ahajournals.org), the analysis outlined researchers’ criticisms of VISP: Participants in VISP may have been administered folate-fortified grain products, the low-dose arm of the study may have been given the recommended daily intake for b12, low-b12 patients in both study arms may have been treated with parenteral b12, test subjects with malabsorption may have been administered an excessively low dose of b12, study participants may have been taking vitamins outside of the study, and patients with significant renal impairment may have failed to response to vitamin therapy.

In the efficacy analysis of VISP, researchers excluded patients with very low and very high b12 levels at baseline (less than 250 pmol/L and greater than 637 pmol/L, respectively, representing the 25th and 95th percentiles), in order to eliminate test subjects with b12 malabsorption, ongoing b12 supplementation outside the study and significant renal impairment. The resulting subgroup was comprised of 2,155 patients, 37 percent female, with a mean age of 66 plus or minus 10.7 years. There was a 21 percent reduction in ischemic stroke, coronary disease and death in the high-b12 dose group compared with the low-b12 does group. Kaplan-Meier survival analysis of the four groups indicated patients with b12 levels at the median or higher at baseline who were randomized to the high-b12 dose showed the best overall outcome, whereas those with baseline b12 levels lower than the median who were assigned the low-b12 dose had the worst general outcome.

In the era of folate fortification, b12 plays a key role in vitamin therapy for total homocysteine may be needed for some patients.

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Date: July 13, 2005 10:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PYCNOGENOL AS A DIETARY SUPPLEMENT

PYCNOGENOL AS A DIETARY SUPPLEMENT

While flavonoid concentrates were used in ancient times to treat a variety of human diseases, modern medicine has failed to utilize their enormous therapeutic potential. We assume RDA standards to provide us with all the vitamin C and bioflavonoids we need to be healthy. Even if these set quantities were accurate for maintaining optimal health, how many of us eat diets nutritious enough to maintain maximum health and protection? In other words, do we consume enough fruits and ve g etables to affo rd us adequate levels of vitamin C and bioflavonoids to provide the free radical protection we need?

“The USDA conducted a study in which they collected dietary information over the course of the year for four independent days. In that study 20% of the adult women had no fruit or juice for four days, and about 45% had no citrus fruit or citrus fruit juice in four days.”6

MALNUTRITION IN THE MIDST OF PLENTY?

Only 9% of our population gets and eats enough fruits and vegetables on a consistent basis. Unquestionably, most of us are not getting enough vitamin C and flavonoid compounds from our diets.

In addition, it’s important to remember that modern farming techniques, pre m a t u re harve sting of fruits and vegetables, indefinite cold storage, freezing, canning and cooking may denature food of its vitamin C and bioflavonoid content. Because we know that diseases are often nothing more than nutritional deficiencies, we must make adequate supplementation a priority if we want to enhance our longevity.

As mentioned earlier, biofl avonoids must combine with vitamin C (ascorbic acid) in order to be effective. Mother nature was well aware of this synergistic relationship, as most plant biof l avonoids accomp a ny vitamin C compounds. In addition, the best, most bio-active and bioavailable flavonols must be chosen for their antioxidant properties. An overwhelming consensus exists that Pycnogenol may be the ideal choice.

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Date: June 25, 2005 07:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: OBESITY: A 2Oth- Century Plague

OBESITY: A 2Oth- Century Plague

Overview

Our modern, fast-paced, high stress, sedentary lifestyle with over-abundant caloric intake is a prescription for obesity. Obesity is an especially critical problem for black women who have nearly twice the rate of obesity of white

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a) The overwhelming majority of all adults are unhappy with their appearance and fitness.
b) More of our children are obese today than ever before.
c) Two out of three people will regain the weight they lose on a diet program within one year.
d) 33 billion dollars is spent annually on weight-loss programs.
e) 33 percent of all adult Americans are over weight.
TABLE 4. Obesity in the United States

women.41 Culturally, being overweight is not looked on graciously, even by physicians.42 There has been no end to the torture we have put ourselves through to be or at least look thin. From corssets to stomach stapling and liposuction to wiring our jaws shut, we’ve tried it all. So where are we today? The following are indicators of abundant obesity: Research and public education efforts are in agreement that excessive dietary fat is the primary cause of adult obesity.2, 46, 47 Despite the fact that food manufacturers have flooded the supermarkets with low-fat, artificially sweetened, “lite” products, we are fatter than ever before. Is maintaining a healthy weight really that difficult? In its simplest form gaining or losing weight is a matter of the balance between energy in and energy out. This simplistic approach led to the early starvation diets. Unquestionably, these conventional very-low-calorie diet plans do not work. For most of us the first thing we lose is our sense of humor; then maybe some weight or possibly our self-esteem. The fact is, as most of us have regrettably discovered, that drastically reducing our calorie tally only serves to slow our metabolism and make us even more efficient at the business of storing and hoarding fat. Since very-low-calorie diets didn’t work alone, exercise was added to the regime. This also failed miserably because the first thing the body does when it is in a starvation mode is to burn off muscle mass so as to conserve energy supplies. In fact, in animal studies, semi-starved animals maintained nearly the same fat to muscle ratio as their well-fed litter mates.43,44 Even worse, when food is again available the body not only gains back all the original fat but an additonal few pounds just in case this ever happens again. Is it any wonder then that yoyo dieting leads to obesity and a host of other problems?42,45 The reconstruction of muscle mass after starvation, a much slower process than regaining body fat, leaves a person feeling weak and even more lethargic than before he started his diet.

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Date: June 21, 2005 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....

GPC (GlyceroPhosphoCholine): Versatile Life Support Nutrient

Parris Kidd, Ph.D.

GPC or GlyceroPhosphoCholine (pronounced gli-sero-fos-fo-ko-lean) is a nutrient with many different roles in human health. It reaches extremely high concentrations within our cells, and its abundance in mother's milk suggests it is crucial to life processes. Clinically, GPC has been most intensively researched for its brain benefits. Biologically, it has great importance for the skeletal "voluntary" muscles, the autonomic nervous system, kidneys, liver, and reproductive organs. GPC goes beyond being a brain nutrient; it is a nutrient for vitality and long life.

Marked Benefits to the Brain

As a dietary supplement, GPC's brain benefits are unique. It boosts mental performance in healthy young people, as shown by three double-blind trials. In trials on middle aged subjects, GPC improved several physiologic measures of mental performance: reaction time, visual evoked potential, and EEG delta slow waves. In the elderly, GPC improves mental performance and provides noticeable revitalisation. In 11 human trials with 1,799 patients, memory, attention, and other cognitive measures improved. So did mood (including irritability and emotional lability), and patients often developed renewed interest in relatives and friends. GPC was well tolerated, and generated no bad drug interactions. A large trial on elderly subjects with memory challenges published in 2003 concluded GPC had significant benefits for these individuals.

GPC Supports Normal Brain Function

Circulatory deprivation or surgery can challenge healthy brain function. GPC can speed recovery and support improved quality of life. In four trials with GPC on 2,804 subjects who experienced difficulties under these circumstances, up to 95% showed good or excellent improvement. GPC consistently improved space-time orientation, degree of consciousness, language, motor capacity, and overall quality of life. The investigators concluded GPC offered marked benefits, with an excellent benefit-to-risk profile. Up to half of patients who survive bypass surgery experience problems with memory and other mental performance. A double-blind trial conducted with bypass survivors for six months determined that the GPC group had no remaining memory deterioration, while the placebo group failed to improve.

GPC Works Through Multiple Mechanisms

GPC supports human health through a variety of mechanisms:

1. It helps keep choline and acetylcholine available to the tissues. Choline is an essential nutrient and GPC appears to be the body's main choline reservoir. GPC in mother's milk represents the baby's main source of dietary choline. Acetylcholine (ACh) is an important substance employed extensively throughout the body. ACh is a major brain transmitter; the motor nerves use ACh to drive the skeletal ("voluntary") muscles; the autonomic nervous system uses it to pace all the organs. ACh is also central to mental and physical endurance, and mind-body coordination.

2. GPC is a major cell-level protectant, not as another antioxidant but in pivotal roles of osmotic pressure regulator and metabolic antitoxin. GPC for osmotic regulation can reach very high concentrations in the kidney, bladder, liver, brain, and other organs. As metabolic protectant, GPC shields proteins against urea buildup.

3. GPC is a major reservoir for cell membrane omega-3 phospholipids. These substances are the major building blocks for cell membranes. Enzymes couple GPC with the omega-3 fatty acid DHA, to make the phospholipid PC-DHA. This makes membranes especially fluid, enabling membrane proteins to perform with better efficiency. GPC produces PC-DHA in the skeletal muscles, wherein fluidity is essential for contraction. Muscles that function abnormally can show GPC deficiency.

4. GPC contributes to both male and female in reproduction. As spermatozoa mature, GPC is used to make PC-DHA that makes their membranes fluid to enable motility. With men, the lower their semen GPC the greater the likelihood of poor sperm motility and with it, infertility. Once semen is inserted into the female, an enzyme in uterine secretions breaks down the semen's GPC into substances that energize the sperm to achieve fertilization.

Dosing, Safety, Tolerability, Compatibility

Oral intake of GPC in the clinical trials was usually 1,200 milligrams (mg) per day, taken early in the day on an empty stomach. A reasonable dietary supplementation regimen is 1200 mg/day, taken in divided doses (AM and PM) between meals for 15-30 days, and thereafter 600 mg/day for maintenance. Symptomatic subjects can take 1200 mg/day until adequate improvement is achieved. Young, healthy subjects may experience benefit from daily intakes as low as 300 milligrams. GPC is very safe, being compatible with vitamins and nutrients and with pharmaceuticals. In clinical trial comparisons, GPC's benefits surpassed the nutrients acetylcarnitine and CDP-choline.

GPC: Nutrient for All Ages

GPC is unmatched for its support of active living and healthy aging. In some 23 clinical trials GPC improved mental performance in all functional categories. GPC can revitalize the aging brain, facilitating growth hormone (GH) release and boosting nerve growth factor actions. GPC's ample presence in human mother's milk suggests it could be conditionally essential. By supporting mental integrity, mind-body integration, the autonomic system, and the body's other organs, GPC enhances the active lifestyle. GPC is remarkable nutritional support for optimal health at any age.

Parris M. Kidd, PhD is a cell biologist trained at the University of California, Berkeley and San Francisco. Since entering the dietary supplement field in 1983, he has published many in-depth reviews of integrative medicine in the journal Alternative Medicine Reviews, and is science columnist for totalhealth magazine. Dr. Kidd is internationally recognized for his accomplishments in dietary supplement product development, documentation and quality control.

Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.

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Date: June 13, 2005 10:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hearty Soy - Soy will cater to your cardiovascular well-being...

Hearty Soy by Joyce Dewon Energy Times, January 5, 2004

It's a diet food, it's a health food. Any way you look at it or eat it, soy's combination of benefits and its versatility as a component of a heart-healthy diet have led to a widespread popularity that continues to grow.

No matter what your taste preference, a soy food is available to satisfy your picky palate and cater to your cardiovascular well-being.

Annual sales of soy in the US continue to grow more than 10% a year, edging toward the $4 billion mark. Today, the average American consumes about 10 mg of soy protein a day, even though the American Heart Association (AHA) recommends taking in at least 25 mg of soy to benefit your heart. Even the Food and Drug Administration (FDA) has signaled its approval of the soy bandwagon, allowing claims that daily soy can help lower the risk of cardiovascular complications.

As Good as a Drug

Researchers who have investigated how soy can help lower cholesterol and shrink the risk of heart disease have concluded that soy, in a diet with fruits and vegetables, can be as effective as cholesterol-reducing drugs (JAMA 7/22/03).

Researchers at the University of Toronto and St. Michael's Hospital compared the cholesterol-lowering power of soy and other vegetarian foods with that of lovastatin, a standard pharmaceutical used to reduce cholesterol.

In the study, scientists fed people a diet that, along with soy, had large amounts of nuts, such as almonds and walnuts, and high-fiber foods like oats and barley plus margarine made with plant sterols (natural substances derived from leafy greens and vegetable oils). Researcher David Jenkins, PhD, a nutrition science professor, thinks these foods may be good at dropping cholesterol because human evolution makes us well-adapted for an "ape diet," one high in fiber, vegetable protein, nuts and plant sterols.

According to Dr. Jenkins, "As we age, we tend to get raised cholesterol, which in turn increases our risk of heart disease. This study shows that people now have a dietary alternative to drugs to control their cholesterol, at least initially." Dr. Jenkins also thinks that soy and a vegetarian diet can be used to maintain normal cholesterol levels.

Soy Meals

Dr. Jenkins' heart-healthy diet, designed to be easily prepared and consumed, includes oat bran bread and cereal, soy drinks, fruit and soy deli slices. For instance, in his study, a typical dinner consisted of tofu baked with eggplant, onions and sweet peppers, pearled barley and vegetables.

Dr. Jenkins adds, "The Food and Drug Administration has approved these cholesterol-lowering foods as having legitimate health claims for heart disease risk reduction. They're also being recommended by the American Heart Association and the National Cholesterol Education Program as foods that should be incorporated into the diet. And we have now proven that these foods have an almost identical effect on lowering cholesterol as the original cholesterol-reducing drugs."

Dr. Jenkins regrets that health practitioners often give drugs to people with high cholesterol instead of trying to control the problem with soy and other vegetarian foods.

Soy Safety Affirmed

Recently, some doctors have spread the story that soy may increase the risk of cancer because natural chemicals in soy act like estrogens, hormones that may contribute to breast and other cancers. However, research has failed to support this supposition.

As Dr. Jenkins points out, "the concerns have been whether soy estrogen might lead to hormone-dependent breast cancer or abnormal sexual development in children, yet we found no evidence to support this."

In another of Dr. Jenkins' studies, people were put on diets high in soy to see how their estrogen levels were affected. Then, the researchers measured estrogen byproducts in their urine. Since estrogen stimulates breast cancer cells to produce a special protein, the researchers measured the amount of this protein produced by each urine sample to calculate how much estrogen was present.

The total estrogenic activity in the urine of women on soy dropped to lower levels than it had been before they ate soy. "This finding suggests that soy may not have the estrogenic effects that were thought to alleviate menopausal symptoms but it refutes claims about its purported hormone risks," Dr. Jenkins says.

The study also demonstrated that soy can reduce the risk of heart disease by lowering levels of oxidized cholesterol, which is thought to stick to coronary artery walls and form dangerous plaques. Dr. Jenkins' other research demonstrates that soy consumption reduces cholesterol in general while also decreasing the amount of LDL (bad) cholesterol in the body and maintaining the HDL (good) cholesterol. According to Dr. Jenkins, this confirms that soy should be promoted for its important role in preventing heart disease without fear that it will promote cancer.

In another study in China, researchers compared the dietary habits of more than 350 women with breast cancer to the foods eaten by more than 1,000 women who did not have cancer (Amer Assoc Canc Res Second Annual Intl Conf Fron Can Prev Res 10/27/03, Abst 1274). They found that eating large amounts of soy did not raise the risk of breast cancer.

Of course, anyone can develop allergies to almost any food, soy included. If eating soy causes you discomfort, find another source of healthy protein (see box on whey protein above).

Isoflavone Benefit

Isoflavones, soy's plant estrogens, are believed to create some of the most significant heart-healthy soy benefits. Consequently, researchers urge those concerned about their cardiovascular health to combine a diet high in soy, fruits and vegetables with exercise for the highest level of heart protection. Cheaper than cholesterol drugs, tastier than many other healthy foods and available in so many forms, soy's popularity will certainly continue to explode. Soy burgers, soy drinks and soy just-about-everything will continue to be a big part of our lives.

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Vitanet ®

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Date: June 10, 2005 02:35 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cholesterol Conundrum

Cholesterol Conundrum

by Jane Lane Energy Times, February 7, 1999

The cholesterol story packs enough subplots to satisfy a soap opera. There's Cholesterol: The Good, the Bad and the Awful. Cholesterol: The Stalker Behind Every (Restaurant) Door. Cholesterol Steals Your Heart Away-to the Mediterranean.

The very image of cholesterol chills the imagination. Lurid and unsavory, it would seem to bob through the bloodstream like blobs of fat congealed on cold soup, slathering itself onto arteries.

Cholesterol is in fact a normal, natural substance in our bodies, found in the brain, nerves, liver, blood and bile. Cholesterol is so crucial that each cell is equipped with the means to synthesize its own membrane cholesterol, regulating the fluidity of those membranes when they are too loose or too stiff.

We manufacture steroid hormones-the female hormones estrogen and progesterone, and the male hormone testosterone-from cholesterol. Adrenal corticosteroid hormones, which regulate water balance through the kidneys, and the hormone cortisone, the vital anti-inflammatory that also governs our stress response, come from cholesterol. Other jobs of cholesterol: production of vitamin D and bile acid (for the digestive process); healing and protecting skin, and antioxidant compensation when vitamin and mineral stores are low.

How can mere mention of this invaluable component in our body chemistry make our blood run cold?

Guilt by Association

Cholesterol's reputation as a bad character actually originates in the crowd it runs with: the lipoproteins, protein molecules to which it binds in order to travel back and forth through the bloodstream to the liver, where it is manufactured.

Not really a nasty round glob of fat at all, cholesterol is a crystalline substance, technically a steroid, but soluble in fats rather than water, thus classified as a lipid, as fats are. Thousands of cholesterol molecules bind with lipoproteins, spherical fat molecules that transport them through the bloodstream.

Three different kinds of lipoproteins participate in this necessary process, not always with the same salutary effect. Here's how they work:

High-density lipoprotein (HDL): referred to as the "good cholesterol." Carries relatively little cholesterol. Travels through the bloodstream removing excess cholesterol from the blood and tissues. HDLs return the surplus to the liver, where it may once again be incorporated into low-density lipoproteins for redelivery to the cells.

Low-density lipoprotein (LDL): the so-called "bad cholesterol," heavily laden with cholesterol, hauling it from the liver to all cells in the body.

Ideally, this system should be in balance. But if there is too much cholesterol for the HDLs to pick up, or an inadequate supply of HDLs, cholesterol may aggregate into plaque groups that block arteries.

Lipoprotein(a), or Lp(a): the "really bad" cholesterol, can step in, providing the glue that actually sticks to the arterial wall. Lp(a) is an LDL particle with an extra adhesive protein wrapped around it, enabling it to attach fat globules to the walls of blood vessels. The potentially deadly results are atherosclerotic ("plaque") deposits. Simple LDL lacks adhesive power and presents little risk for cardiovascular disease.

Researchers confirmed the existence of Lp(a) in the August 1996 issue of the Journal of the American Medical Association, disclosing that high levels of Lp(a) in the blood can double a man's risk of heart attack before age 55. Doctors estimate that about 20% of all Americans carry elevated levels of Lp(a).

One troubling aspect of the report, part of the ongoing 40-year-old Framingham Study, concerned the fact that the men who suffered heart attacks entered the project with no signs of heart disease and only slightly elevated cholesterol.

But during the 15-year investigation, 129 men out of 2,191 developed premature heart disease.

The culprit? High levels of Lp(a)

Experts don't know for certain where Lp(a) comes from, or its normal function, although they suspect the body's quotient of Lp(a) is mostly due to your genes. According to the study, they also believe that aspirin, a blood thinner, and red wine (or its grapeseed and skin extracts) may mitigate the damage of Lp(a). That also would explain why the French, who tend to wash down their fat-rich diet with red wine, experience a relatively moderate incidence of cardiovascular disease

The Terrible Triglycerides

The body also transports fats via triglycerides (TGs), the main form of body fat and the storehouse for energy. Edible oils from seeds, egg yolk and animal fats also are composed chiefly of TGs. Although not as corrosive as LDL, excess TGs intensify heart disease potential when they oxidize and damage artery linings or induce blood cells to clump.

An "acceptable" level of triglycerides is thought to be 200 milligrams, although under 150 is probably healthier. And some researchers think your triglyceride reading should be below 100. High triglycerides and low HDL often occur together, increasing the risks of cardiovascular disease, high blood pressure, heart and kidney failure and other degenerative diseases.

What To Do About Your Cholesterol

Have it checked. High cholesterol alone shows no symptoms. Your health practitioner can perform a laboratory test to measure your levels. Thoroughly share your own medical history and as much as you know about your family members: heredity and related illnesses definitely are important influences. People with diabetes, for example, can have high levels of triglycerides, which also may lead to pancreatitis (painful inflammation of the pancreas) at extremely high levels.

According to the National Cholesterol Education Program, a reading of under 200 mg/dL is desirable; 200 to 239 is borderline high; 240 and above is high. Your LDL level should be 130 or under; HDL should not be lower than 35. A triglyceride level below 200 is considered desirable; readings above 400 are high.

Adjust your diet. Cholesterol levels are readily controllable, primarily through changes in your diet. Leslie C. Norins, MD, PhD, suggests all-out war in his Doctor's 30-Day Cholesterol Blitz (Advanced Health Institute) with saturated fats, which raise cholesterol more than any other component in your diet, as your number-one target. Out with saturated fats like butter, cheese, whole milk, ice cream, red meat and some vegetable fats found in tropical oils like coconut and palm; in with fruits, vegetables, brown rice, barley (a good source of soluble fiber, the kind that soaks up fats and cholesterol and escorts them out of the body), beans, potatoes and pasta, prepared or dressed with monounsaturated fats in olive and canola oils (the so-called Mediterranean diet concept). Feast on cold-water fish (mackerel, salmon, sardines and herring) rich in omega-3 fatty acids that help reduce serum lipids, among many other healthful advantages.

Exercise. Move it and lose it are the words to live by when it comes to cholesterol. Researchers from the Stanford Center for Research in Disease Prevention reported in the July 2, 1998 New England Journal of Medicine (vol. 339, pages 12-20) that a weight-loss diet like that of the National Cholesterol Education Program plus exercise significantly lowered LDL (bad) cholesterol levels for men and postmenopausal women. The diet alone failed to lower LDL in these folks with high-risk lipoprotein.

Educate yourself. In addition to your health practitioner, books and magazines can guide you in cholesterol management. A trove of information is the National Cholesterol Education Program (NCEP), launched in 1985 by the National Institute of Health. Their address is: National Cholesterol Education Program, Information Center, P.O. Box 30105, Bethesda, MD 20824-0105; telephone (301) 251-1222; they're on the web at /nhlbi/.

Recommended Reading: Fats that Heal, Fats that Kill (Alive, 1993), by Udo Erasmus.

Prescription for Nutritional Healing (Avery, 1997), by James F. Balch, MD, and Phyllis A. Balch, CNC.

The Healthy Heart Formula (Chronimed, 1997), by Frank Bary, MD.

Eradicating Heart Disease (Health Now, 1993), by Matthias Rath, MD.

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VitaNet ® Staff

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Date: May 26, 2005 10:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: the effect of vinpocetine on cerebral blood flow (CBF) ...

Abstract Objectie :To investigate the effect of vinpocetine on cerebral blood flow (CBF) in the compromised circulation of a stroke affected hemisphere using transcranial Doppler (TCD) and near infrared spectroscopy (NIRS) methods. Methods : 43 patients with ischemic stroke were randomized into vinpocetine (VP) and placebo group in a double blind, placebo-controlled study of the effect of a single-dose i.v. infusion of vinpocetine on cerebral blood perfusion and oxygenation. In the VP group 20 mg VP in 500 ml saline, in the placebo group 500 ml saline alone were administered. The concentrations of oxy-, reduced- and total hemoglobin were measured by NIRS frontolaterally on the side of lesion while the mean cerebral blood flow velocity (CBFV), the pulsatility index (PI) and Doppler spectral intensity (DSI) were monitored by TCD in the middle cerebral artery on the same side. Values were averaged for the first 5 min prior to the infusion and for the last 5 min of infusion and they were compared between groups. Results : The concentration of all three chromophores increased during infusion in the VP group (mean dHbT=1.03, CI95=0.84, P=0.058; mean dHbO=0.92, CI95=0.91, P=0.071; mean dHb=0.10, CI95=0.21, P=0.297). The HbT and HbO showed a substantially smaller increase in the placebo group (mean dHbT=0.31, CI95=0.74, P=0.22; mean dHbO=0.57, CI95=0.80, P=0.094) while the Hb decreased (mean dHb=-0.26, CI95=0.29, P=0.05). Comparing to the placebo group Hb increased significantly in the VP group (P=0.027) while the increase of HbO and HbT did not reach the level of significance (P=0.29 and 0.11). DSI showed a significantly larger increase in the VP than in placebo group (dDSI=25.8 CI95=8.8 [VP]; dDSI=3.3, CI95=3.7 [Placebo], P
0.005). The CBFV and PI did not differ significantly between groups. (dVm=5.02.98 cm/s [VP], dVm=4.12.57 cm/s [Placebo], P=0.28; dPI=0.08 [VP], dPI=0.09 [Placebo]; P=0.47). Conclusion :VP increases cerebral perfusion and parenchymal oxygen extraction as well. The increased perfusion was indicated by NIRS and by TCD measurement of DSI while conventional velocity and pulsatility measurements failed to detect theses effects. NIRS is a sensitive, www.elsevier.com/locate/ejultrasou Abbre
iations :BP, blood pressure; CI, confidence interval; CBFV, cerebral blood flow velocity; CT, computer tomography; CytO, cytochrome-oxydase; DSI, Doppler spectral intensity; Hb, deoxyhaemoglobin; HbO, oxyhaemoglobin; HbT, total haemoglobin; HR, heart rate; MAP, mean arterial pressure; MCA, middle cerebral artery; MRI, magnetic resonance imaging; NIRS, near infrared spectroscopy; PET, positron emission tomography; PI, pulsatility index; TCD, transcranial Doppler; US, ultrasonography; VP, vinpocetine.

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Date: May 12, 2005 10:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Under-Reported (and Underappreciated) Cholesterol control.

Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Control

Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.

The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.

Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.

The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)

Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.

Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.

How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look.

Gugulipid

In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.

Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."

Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.

Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.

Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.

Pantethine

Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6

Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.

Niacin

When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.

There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12

Tocotrienols

We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.

Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.

The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."

It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.

References

1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.

2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.

3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.

4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.

5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.

6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.

7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.

8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.

9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.

10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.

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Control Cholesterol with the following Supplements

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Date: May 09, 2005 11:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Red Yeast Rice can Lower Cholesterol. Scientific Studies prooven

Department of Biochemical Pharmacology, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100083, China.

Long-term effects of Cholestin (Monascus purpureus rice; red yeast rice) on serum lipids and severity of atherosclerosis were examined in rabbits fed for 200 days on a semi-purified diet containing 0.25% cholesterol. Serum total cholesterol was 25 and 40% lower, respectively, in rabbits fed 0.4 or 1.35 g/kg/day of Cholestin (Monascus purpureus rice; red yeast rice) compared to controls. This treatment also lowered serum LDL cholesterol. This 200-day treatment significantly reduced serum triglycerides and atherosclerotic index (ratio of non-HDL-cholesterol to HDL-cholesterol). Although similar reductions of total, LDL-cholesterol and triglycerides were observed, a parallel group of rabbits fed lovastatin (0.0024 g/kg/day) failed to reduce the index significantly. Apolipoprotein A(1) was increased and apolipoprotein B was reduced in all treatment groups. Severity of atherosclerosis was reduced significantly in all treatment groups. The sudanophilic area of involvement was 80.6% in controls, and reduced significantly; to 30.1% on the low dose (Monascus purpureus rice; red yeast rice), and 17.2% on the high dose. Lovastatin reduced severity of lesions by 89% (sudanophilia) and 84% (visual). Visual grading of lesion severity showed reduction by 38% and 68%.

PMID: 12873712 [PubMed - indexed for MEDLINE]

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