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	Clean and Pure Sweetness from Stevia That is Unmatched by Other Brands	Darrell Miller	10/22/24
	The Benefits of Vitamin C for Skin Health	Darrell Miller	5/24/24
	Why Your Sodium to Potassium Ratio Is Important	Darrell Miller	8/4/23
	Why You Need NOW® Vitamin B-12 Instant Energy	Darrell Miller	10/26/22
	Fiber doesn't just do wonders for your gut: It also can also keepbreast cancer at bay	Darrell Miller	4/23/19
	Study confirms the healing potential of black cumin for asthmaticpatients	Darrell Miller	2/27/19
	Congress Finally Frees Hemp From Jail: Big News For Farmers and CBDIndustry	Darrell Miller	1/6/19
	CBD Oil Benefits for Dogs	Darrell Miller	2/17/18
	Fat, fructose and calories: 5 nutrition 'facts' we used to believe	Darrell Miller	9/15/17
	Research pilot explores industrial hemp	Darrell Miller	9/7/17
	Hemp 101: What It Is, And How It Can Save The World	Darrell Miller	8/11/17
	If you get less than 7 hours of sleep, this is what can happen to your belly fat	Darrell Miller	7/21/17
	The 8 Most Important CBD Studies Ever Published	Darrell Miller	5/28/17
	Keto Diet Food List, Including the Best vs. Worst Keto Foods	Darrell Miller	5/14/17
	Scientists Call for Restrictions on Ibuprofen & other OTC Painkillers After Deadly Risks Discovered	Darrell Miller	4/9/17
	Trace minerals, supporting the immune system	Darrell Miller	2/27/17
	Top 15 Reasons Why Sweet Potatoes Are Good For Diabetic Patients	Darrell Miller	2/17/17
	Hemp is a Wonder Plant	Darrell Miller	2/10/17
	Link between dietary restriction, longevity examined	Darrell Miller	2/9/17
	Possible new head of the FDA is a supporter of medical marijuana … Could Trump's FDA finally stop suppressing cannabis?	Darrell Miller	2/4/17
	Did cannabis oil prove to be a miracle cure for this little boy with epilepsy?	Darrell Miller	1/16/17
	Reducing salt intake may help protect kidney patients’ heart and kidney health	Darrell Miller	12/3/16
	Can Resveratrol Help Fight DNA Damage?	Darrell Miller	1/21/13
	Can L-Carnosine Be Used As An Anti-Aging Vitamins?	Darrell Miller	4/18/12
	Raspberry Ketones can help you in losing Weight	Darrell Miller	2/7/12
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Date: October 22, 2024 05:43 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Clean and Pure Sweetness from Stevia That is Unmatched by Other Brands

Discover the Benefits of Kal Brand Sure Stevia Powder Extract

In recent years, the surge in health consciousness has led to a growing demand for alternative sweeteners. Among these, Kal Brand Sure Stevia Powder Extract stands out for its exceptional properties and versatile uses.

What is Stevia?

Stevia is a natural sweetener derived from the leaves of the Stevia rebaudiana plant. Unlike sugar, stevia is free from calories, making it an attractive option for health enthusiasts. The compound responsible for stevia's sweetness is stevioside, which is several times sweeter than table sugar, allowing it to sweeten foods and drinks without the health drawbacks associated with sugar.

Why Choose Stevia Over Sugar?

Stevia's benefits extend beyond its calorie-free nature. It has a minimal impact on blood sugar levels, making it suitable for individuals with diabetes or those looking to maintain balanced glucose levels. In addition, stevia does not contribute to tooth decay, a significant advantage over sugar. Therefore, it's not just an excellent alternative for those with dietary restrictions but also for those concerned with dental health.

The Superiority of Kal Brand

Kal Brand Sure Stevia Powder Extract differs from conventional products through its high purity and sans bitterness formula. Many stevia products on the market can leave a distinct aftertaste; however, Kal's special extraction process ensures a clean, pure sweetness. This attention to detail provides a refined taste experience, allowing you to enjoy your favorite foods and beverages without compromising on flavor.

The No Aftertaste Advantage

One of the primary concerns with using stevia as a sweetener is the aftertaste that can often accompany its use. However, Kal Brand Sure Stevia Powder Extract has effectively addressed this issue through a meticulous refinement process. By employing advanced extraction techniques, Kal Brand has managed to eliminate the unwanted bitterness that many stevia products exhibit. This innovation makes Kal Sure Stevia Powder distinctive, providing a seamless sweetness akin to sugar, devoid of any lingering aftertaste. Consequently, consumers can integrate this stevia into a variety of culinary applications with confidence, knowing that it won't alter the intended flavor profile of their dishes and beverages. This characteristic solidifies its position as an ideal sweetener for connoisseurs seeking both health benefits and an uncompromised taste experience.

Versatility in Use

Kal Brand Sure Stevia Powder Extract is remarkably versatile. It can be seamlessly integrated into numerous recipes, from sweetening a morning coffee to enhancing a homemade dessert. Furthermore, its concentrated sweetness means that only a small amount is needed, making it an economical and efficient choice.

Tips for Cooking and Baking

To use Kal Brand Sure Stevia in your culinary creations, a basic understanding of conversions can be helpful. As it is much sweeter than sugar, the amount of stevia needed is substantially less. A reliable rule of thumb is to use about a half a teaspoon of stevia extract for each cup of sugar. Moreover, when incorporating it into recipes, consider the bulk and moisture sugar provides; you may need to adjust recipes to achieve the desired texture.

Health Benefits in Focus

Several studies have explored the potential health benefits of incorporating stevia into a diet. Stevia may help aid in weight management due to its zero-calorie content, allowing individuals to satisfy their sweet tooth without caloric accumulation. Furthermore, there are indications that stevia possesses antioxidant properties, which can contribute to overall health and wellness.

Transitioning to Stevia

Switching from conventional sugar to stevia may seem daunting at first, but the rewards are worth the effort. Gradual introduction into your diet can ease the transition. Start by replacing sugar in your coffee or tea, then slowly incorporate it into baking. This phased approach can help adjust your palate and harness the maximum benefits of Kal Brand Sure Stevia.

Make the Switch Today

As consumers increasingly prioritize health and wellness, choosing a natural sweetener like Kal Brand Sure Stevia Powder Extract is not only a wise decision but also an achievable step towards a healthier lifestyle. With its exceptional purity, versatility, and health benefits, there has never been a better time to optimize your sugar intake. Take action now; explore the delicious possibilities that this remarkable product offers and enjoy the sweetness of life without compromise. Try Kal Brand Sure Stevia Powder Extract today and experience a revolutionary change in your dietary habits.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6617)

Date: May 24, 2024 04:34 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Benefits of Vitamin C for Skin Health

The Benefits of Vitamin C for Skin Health

Vitamin C, also known as ascorbic acid, plays an essential role in maintaining overall skin health. This potent nutrient offers numerous benefits, making it a staple ingredient in many skincare products. Below, we explore some of the key advantages of incorporating Vitamin C into your skincare routine.

Promotes Collagen Production

Collagen is a structural protein that maintains the skin's firmness and elasticity. As we age, collagen production declines, leading to signs of aging such as wrinkles and fine lines. Vitamin C is a crucial co-factor in the synthesis of collagen, helping to keep the skin plump and youthful. Regular application of Vitamin C can stimulate collagen production, making the skin look smoother and more resilient.

Accelerates Wound Healing

Vitamin C's role in collagen production also extends to wound healing. This nutrient supports the repair of damaged skin by promoting new tissue growth. Whether dealing with minor cuts, abrasions, or post-surgical wounds, applying Vitamin C can expedite the healing process and reduce the risk of scarring.

Antioxidant Protection

Environmental factors like pollution and UV radiation generate free radicals, molecules that damage skin cells and accelerate aging. Vitamin C is a powerful antioxidant that neutralizes free radicals, protecting the skin from oxidative stress. By incorporating Vitamin C into your skincare routine, you can shield your skin from environmental damage and maintain a healthier complexion.

Boosts Immune Function

A robust immune system is vital for overall skin health. Vitamin C bolsters the immune system, making it an essential component of both internal and external treatments. A well-functioning immune system can better fend off skin infections and inflammatory conditions, contributing to clearer, more radiant skin.

Reduces Hyperpigmentation

Hyperpigmentation occurs when certain areas of the skin produce excess melanin, resulting in dark spots or patches. Vitamin C can inhibit melanin production, helping to lighten hyperpigmented areas. Over time, consistent use of Vitamin C can promote a more even skin tone, reducing the appearance of age spots, sun spots, and melasma.

Enhances Skin Radiance

One of the most sought-after benefits of Vitamin C is its ability to enhance skin radiance. By improving skin texture and tone, Vitamin C can give your complexion a noticeable glow. Regular use of Vitamin C serums or creams can help achieve a brighter, more luminous look.

Prevents Sagging

Loss of skin elasticity leads to sagging, which is a common sign of aging. By promoting collagen synthesis and offering antioxidant protection, Vitamin C can help maintain the skin's structural integrity. This results in tighter, firmer skin, reducing the likelihood of sagging.

Combats Environmental Damage

Exposure to environmental pollutants can wreak havoc on your skin, causing premature aging and damage. Vitamin C acts as a protective barrier, reducing the detrimental effects of pollutants. Adding Vitamin C to your skincare regimen helps combat environmental damage, ensuring your skin remains healthy and vibrant.

Supports Hydration

Maintaining adequate moisture levels is crucial for healthy skin. Vitamin C can support skin hydration by enhancing the skin barrier function and reducing water loss. This ensures that your skin stays supple and well-moisturized, reducing the risk of dryness and irritation.

Skin Repair and Protection Against Oxidative Stress

Vitamin C not only protects against oxidative stress but also aids in repairing the skin. By promoting cell regeneration and improving skin texture, Vitamin C helps to rejuvenate and restore damaged skin.

Are You Ready to Experience What Vitamin C Can Do?

Ready to experience the transformative benefits of Vitamin C for your skin? Don't wait any longer. Invest in a high-quality Vitamin C serum or cream today and take the first step toward healthier, more radiant skin. Visit our store now to explore our range of Vitamin C products tailored to meet your skincare needs. Enhance your skin's vitality and glow with the power of Vitamin C – your skin will thank you!

Food Sources of Vitamin C

Incorporating Vitamin C into your diet is a great way to boost your skin health from within. Here are some excellent food sources of this essential nutrient:

• Citrus Fruits: Oranges, grapefruits, lemons, and limes are well-known for their high Vitamin C content.
• Strawberries: These delicious berries are not only rich in antioxidants but also pack a substantial amount of Vitamin C.
• Kiwi: This small, nutrient-dense fruit provides more Vitamin C than an orange per serving.
• Bell Peppers: Among vegetables, bell peppers are a top source of Vitamin C, especially the red and yellow varieties.
• Broccoli: This cruciferous vegetable offers a considerable amount of Vitamin C along with other beneficial nutrients.
• Brussels Sprouts: Another vegetable rich in Vitamin C, Brussels sprouts are a great addition to any meal.
• Papaya: This tropical fruit is an excellent source of Vitamin C and other beneficial compounds.
• Tomatoes: Whether fresh, in sauces, or as juice, tomatoes are a versatile source of Vitamin C.
• Spinach: This leafy green not only provides Vitamin C but also a host of other vitamins and minerals.

Including these foods in your diet can help ensure you receive adequate Vitamin C, supporting both your overall health and your skin's vitality.

Convenience of Taking Vitamin C: Supplements vs. Food Sources

While both food sources and supplements offer ways to meet your daily Vitamin C needs, supplements provide unmatched convenience. Incorporating Vitamin C-rich foods such as oranges, strawberries, and bell peppers into your diet requires careful meal planning and preparation and adds calories to your diet. In contrast, Vitamin C supplements offer a quick and efficient alternative, allowing you to ensure adequate intake regardless of your dietary habits. This convenience makes supplements particularly appealing for busy individuals or those with specific dietary restrictions, enabling them to maintain optimal Vitamin C levels effortlessly.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6602)

Date: August 04, 2023 02:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why Your Sodium to Potassium Ratio Is Important

The typical Western diet is largely comprised of processed foods, which are notoriously high in processed table salt. This results in an imbalance in the sodium to potassium ratio, a significant health concern. Sodium is necessary for a variety of bodily functions; however, too much can be detrimental, leading to hypertension and other cardiovascular diseases. Simultaneously, potassium is often neglected, despite its crucial role in muscle function, nerve signaling, and balancing fluids.

The general dietary advice suggests a potassium to sodium intake ratio of 3:1. However, the reality in diets, particularly those in America, often sees this ratio inverted. The excessive sodium consumption is linked to a myriad of health complications, including high blood pressure and heart disease. Conversely, potassium, a mineral that aids in nerve function and muscle control, is consumed in insufficient quantities. This is a troubling trend that underscores the importance of dietary change towards natural, unprocessed foods.

The importance of potassium is often overshadowed by the emphasis on limiting sodium for reducing chronic disease risk factors. Potassium plays an essential role in maintaining healthy blood pressure levels by counteracting the effects of sodium. Furthermore, the mineral is crucial for other functions like heart and muscle cell functioning, nerve transmission, and maintaining fluid balance.

A study published in the New England Journal of Medicine discovered that individuals with the lowest risk for heart complications or death from any cause were those consuming between four to six grams of sodium per day. This is a fascinating discovery, as this intake is significantly higher than the U.S. daily recommended limits. It suggests a need for a reconsideration of current sodium intake guidelines.

Another consideration to balance the sodium-potassium ratio is the type of salt consumed. Unprocessed, natural salts like sea salt and Himalayan salt contain higher potassium levels compared to standard table salt. These natural salts provide a variety of minerals and trace elements that contribute to our overall health and wellness. It's crucial to note that switching to natural salt should be part of a broader shift towards a diet rich in fresh, unprocessed foods.

Why You Should Focus on Increasing Potassium

While it's beneficial to monitor and moderate sodium intake, it's equally important to shift our focus towards increasing potassium consumption. Potassium-rich foods, such as leafy green vegetables, bananas, potatoes, and beans, not only contribute to a well-rounded and nutritious diet but also help in maintaining an optimal sodium-potassium balance in the body. A high potassium intake can counteract the effects of sodium, aiding in blood pressure regulation and reducing the risk of cardiovascular diseases. Moreover, an elevated potassium level supports various bodily functions, including nerve transmission, muscle contraction, and fluid balance. Thus, prioritizing potassium intake forms a cornerstone for an overall healthier dietary approach. It is recommended that individuals consume 5 grams of potassium daily and potassium to salt ratio should be 2 to 1. To boost potassium intake, one can take a potassium supplement or add the following foods to their diet or both: Watermelon, Orange juice, Boiled red potatoes, Avocado, Bananas, Cantaloupe, Oranges, Coconut water, Tomatoes, Yogurt, Winter squash, and Wild-caught salmon.

Why Low-Salt Advice Can Be Harmful

Contrary to popular belief, adhering to low-salt advice can sometimes pose risks to certain individuals. While it is true that excessive sodium intake can lead to high blood pressure and heart problems, sodium still plays a vital role in our bodies. It assists in nerve conduction, muscle contraction, and maintaining the body's fluid balance.

In fact, low sodium levels in the body, a condition known as hyponatremia, can lead to symptoms such as headache, nausea, fatigue, and in severe cases, coma or even death. Moreover, a low-salt diet may lead to increased levels of cholesterol and triglycerides, hormonal imbalances and insulin resistance. This can potentially elevate the risk of developing cardiovascular disease.

Low-salt diets can also exacerbate the risk of certain health conditions. For instance, individuals with conditions like Addison's disease or certain kidney disorders, where the body struggles to maintain a balance of electrolytes, might find a low-salt diet harmful.

Therefore, it is crucial to balance the intake of sodium, considering both the potential risks associated with too much, or too little, sodium. The key is to consume sodium from natural and unprocessed sources, such as Himalayan salt, fruits, vegetables, grains, and lean meats, which also provide a host of other nutrients necessary for overall health. As with most things in nutrition, moderation and balance seem to hold the answer rather than extreme restriction. The RDA - recommended daily allowance of sodium is 3.5 grams. It is advised to consume 3.5 grams of natural salt each day by way of foods or combination of foods plus Himalayan salt to reach that goal.

The Impact of Excessive Salt Intake on Certain Health Conditions

While moderate salt intake is vital for normal physiological functions, its excessive consumption can have detrimental effects, particularly for individuals with certain health conditions. For instance, endocrine disorders, high aldosterone levels, Cushing's syndrome, and elevated cortisol levels can all heighten the body's sensitivity to sodium, making it even more essential to monitor and limit salt intake.

Endocrine disorders, which involve imbalances in the body's hormone production, can often lead to increased sodium retention, exacerbating issues of water retention and swelling. Similarly, high aldosterone levels, a hormone that regulates sodium and potassium balance, can cause the body to retain excessive sodium, leading to high blood pressure and potential damage to the cardiovascular system.

Cushing's syndrome, a condition characterized by excessive cortisol production, can lead to a host of symptoms, including high blood pressure and rapid weight gain, both of which can be intensified by high sodium intake. The excessive cortisol found in Cushing's syndrome promotes sodium retention, further elevating the risk for hypertension.

Similarly, elevated cortisol levels, even outside of Cushing's syndrome, can lead to heightened sodium retention, contributing to high blood pressure, fluid retention, and an imbalance of electrolytes. Therefore, individuals with these conditions should be particularly mindful of their sodium intake.

In these scenarios, reducing salt consumption can help mitigate the associated health risks and symptoms. Switching to a diet rich in whole, unprocessed foods, and taking conscious steps to limit the use of added table salt can play a crucial role in managing these health conditions. As always, it is essential to seek personalized advice from a healthcare professional, as individual needs may vary.

In summary, while salt is often villainized in the health community, its consumption, especially from natural sources, is vital for maintaining bodily functions like nerve conduction, muscle contraction, and fluid balance. However, excessive or inadequate sodium intake can have adverse health effects, such as hypertension, imbalances in cholesterol and triglycerides, and even hyponatremia in severe cases. Certain health conditions, including endocrine disorders, high aldosterone levels, Cushing's syndrome, and elevated cortisol levels, can also exacerbate these risks, making it crucial for individuals with these conditions to carefully monitor their salt intake. On the other hand, increasing potassium intake can help maintain an optimal sodium-potassium balance, reducing blood pressure and lowering the risk of cardiovascular diseases. In a nutshell, moderation and balance are key in sodium consumption, but the emphasis should be on consuming more potassium-rich foods to ensure your potassium intake is higher than sodium levels which will ensure a healthier dietary approach.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6582)

Date: October 26, 2022 11:06 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why You Need NOW® Vitamin B-12 Instant Energy

If you're anything like me, you're always on the go and looking for ways to improve your energy and mood. I'm happy to say that I've found the perfect solution in NOW® Vitamin B-12 Instant Energy packets.* These convenient packets are perfect for when you need a little boost - whether you're at work, at the gym or out with friends.* With a blend of three forms of B-12 and additional nutrients such as chromium and creatine, NOW® Vitamin B-12 Instant Energy can give you the edge you need to power through your day.*

The Benefits of vitamin B-12

Vitamin B-12 is an essential nutrient that helps support cellular energy production.* It also plays a role in mood, memory and concentration.* Unfortunately, many people don't get enough vitamin B-12 in their diet due to poor absorption or dietary restrictions.* This is where NOW® Vitamin B-12 Instant Energy comes in - it's the perfect way to get the vitamin B-12 your body needs.*

NOW® Vitamin B-12 Instant Energy is easy to use and convenient

I love that NOW® Vitamin B-12 Instant Energy comes in packet form - it's so easy to grab and go when I'm on the go!* I also appreciate that it's free of artificial colors, flavors, sweeteners and preservatives.* These packets are perfect for when I'm traveling or just running around town.*

If you're looking for a quick and easy way to improve your energy and mood, I highly recommend trying NOW® Vitamin B-12 Instant Energy packets.* With a blend of three forms of vitamin B-12, chromium and creatine, NOW® Vitamin B-12 Instant Energy can give you the edge you need to power through your day.* Give it a try today!*

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6527)

Date: April 23, 2019 03:29 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Fiber doesn't just do wonders for your gut: It also can also keepbreast cancer at bay

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6166)

Date: February 27, 2019 09:57 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study confirms the healing potential of black cumin for asthmaticpatients

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6058)

Date: January 06, 2019 04:20 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Congress Finally Frees Hemp From Jail: Big News For Farmers and CBDIndustry

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5937)

Date: February 17, 2018 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD Oil Benefits for Dogs

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5531)

Date: September 15, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Fat, fructose and calories: 5 nutrition 'facts' we used to believe

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5250)

Date: September 07, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Research pilot explores industrial hemp

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5234)

Date: August 11, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Hemp 101: What It Is, And How It Can Save The World

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5108)

Date: July 21, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: If you get less than 7 hours of sleep, this is what can happen to your belly fat

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5011)

Date: May 28, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The 8 Most Important CBD Studies Ever Published

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4717)

Date: May 14, 2017 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Keto Diet Food List, Including the Best vs. Worst Keto Foods

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4615)

Date: April 09, 2017 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Scientists Call for Restrictions on Ibuprofen & other OTC Painkillers After Deadly Risks Discovered

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4386)

Date: February 27, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Trace minerals, supporting the immune system

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4032)

Date: February 17, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Top 15 Reasons Why Sweet Potatoes Are Good For Diabetic Patients

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3959)

Date: February 10, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Hemp is a Wonder Plant

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3918)

Date: February 09, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Link between dietary restriction, longevity examined

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3914)

Date: February 04, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Possible new head of the FDA is a supporter of medical marijuana … Could Trump's FDA finally stop suppressing cannabis?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3882)

Date: January 16, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did cannabis oil prove to be a miracle cure for this little boy with epilepsy?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3790)

Date: December 03, 2016 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Reducing salt intake may help protect kidney patients’ heart and kidney health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3561)

Date: January 21, 2013 01:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Resveratrol Help Fight DNA Damage?

How resveratrol helps in fighting DNA damage

Resveratrol is a naturally occurring antioxidant produced by plants to protect them against attacks by predators such insects, bacteria or fungi. This antioxidant which has been the subject of several scientific studies is usually found in large quantities in grape skin or red wine. Although the body can function without it which means that you can not be termed as deficient of this nutrient, the compound is known to have immense health benefits. Scientists claim that human beings have not yet fully discovered the real benefits that can be derived from this antioxidant.

Scientists have demonstrated that Resveratrol is quite effective in fighting DNA damage which is responsible for aging as well as disorders that are associated with aging including Parkinson's and Alzheimer's disease. Cell degeneration in vital organs is usually linked to certain factors. An important factor that causes cell loss is the presence of reactive oxygen species (ROS) by mitochondria in the cell which is responsible for cell death and DNA damage. Preventing mitochondria turnover and bio-genesis guards against oxidative mitochondria thus promoting healthy aging.

Cell degeneration has been effectively controlled by using a diet that is low in calories so as to increase mitochondria biogenesis. Adding resveratrol to your diet has the same effect since this antioxidant mimics dietary restriction thus delaying diseases related to aging.

The compound has been known to stall the aging process by acting as sirtuin activator. It is also responsible for various effects on fat cells which alter fat mass by acting on cell viability and adipogenesis in mature preadipocytes. Laboratory tests have demonstrated that this compound stimulates bio-genesis which helps in delivering immense health-related benefits in mice. The antioxidant fights off cancer which occurs when there is cell damage during cell division. The compound stops cell division in order to allow enzymes repair damaged genes .It also prevents carcinogenic metabolism, a common cause of DNA damage.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2814)

Date: April 18, 2012 07:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can L-Carnosine Be Used As An Anti-Aging Vitamins?

Carnosine And Your Health

Carnosine has gained widespread popularity as an anti-aging compound despite some skeptical voices in the scientific community. Many studies lend credence to its value for treating the signs of aging and its antioxidant properties are well researched. Carnosine is also widely used as a supplement to prevent complications from diabetes such as nerve and kidney damage. This article will discuss the details of what it is, what it seems to do in the body and how it may be able to help people restore a more youthful state of health.

Discovered in Russia more than a century ago, Carnosine is an amino acid and is found primarily in muscle, skeletal and nervous tissue (including the brain). As such the primary dietary sources are animal products such as fish, poultry and red meat. It is common for vegetarians to become deficient in it, making them ideal users of carnosine supplements.

Glycation

There is a gradual decline in carnosine levels as we age, which lends credence to the claims of its anti-aging properties. The most clearly established property of carnosine is its ability to act as an anti-glycation agent. Glycation is a process the body goes through to release energy from sugar but which ends up producing harmful substances. Carnosine can neutralize some of these already formed substances and also prevent the process from forming new ones. Some researchers believe glycation may be the key behind the benefits of caloric restriction, making carnosine the long awaited magic pill that can mimic its effect as a longevity treatment without the deprivation of restricting food intake.

Antioxidant Properties

In addition to carnosine's anti-glycation effect, it also has antioxidant properties. The oxidation process which the body goes through naturally produces the well known "free radicals" which slowly damage the cells and are thought to play an important role in the aging process. Carnosine can neutralize this protecting the cells. This also has a beneficial effect at keeping the telomeres from shortening, which is thought to be the main cause of the aging process. Telomeres are the buffers at the ends of DNA code that protect the code from being corrupted, so when the telomeres become shorter there is less protection and a greater chance of things going wrong. This makes carnosine's protective benefits of great importance in the fight against aging.

Carnosine Protects The Cells From Damage Like Radiation

Studies show that carnosine can protect the cells from radiation damage, which is particularly useful for cancer patients who have to undergo radiological treatment. It also promotes the healing of wounds and protects cell membranes. Some studies demonstrate that it can literaly repair old cells and make them younger. As it binds easily to toxic metals, turning them into powerful antioxidants, it is very effective at protecting the body from their harmful impact.

Some of the most promising uses of carnosine are for the treatment and prevention of Alzheimer, the signs of aging in the skin, cataract, nerve and kidney damage and heart disease. The recommendation for use as a supplement is 500 miligrams, though the body can deal safely with much larger doses. Give Carnosine a try today and experience the difference yourself.

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Date: February 07, 2012 02:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Raspberry Ketones can help you in losing Weight

According to NHANES (National Health and Nutrition Examination Survey), more than two thirds of Americans are overweight and about one third are obese. Obesity is definitely a serious medical condition that not only reduces your stamina, but can also lead to various health complications such as hypertension, heart disease, diabetes, cancer, sleep apnea, menstrual irregularities, atherosclerosis and many more.

Any attempt to lose weight can succeed only when it is multidimensional. In order to get the desirable results, you will have to bundle various weight loss techniques to get the desired results. In some instances, this can also lead to deleterious side effects. For example, stringent dietary restrictions may result in various nutritional disorders such as goiter, osteoporosis, scurvy and so on. Excessive exercises can also cause various maladies such as depression, fatigue, muscular injuries and insomnia. So What Are Raspberry Ketones?

Raspberry, which is an edible fruit, is quite rich in Vitamin B, antioxidants, folic acid, riboflavin, niacin, magnesium potassium copper and manganese. Aside from these, it also has large amounts of ketones, referred to as “Raspberry Ketones”. Actually, ketones are phenolic compounds that help you in losing excess body weight without harming your body in any way.

How do Raspberry Ketones work?

Raspberry ketones, being natural substances work in an entirely different way. Unlike various other weight loss therapies, they work all alone and in the most effective way. They persuade the body to release norepinephrine, which is a stress hormone and affects that part of your brain, which controls responses and attention.

Along with norepinephrine, raspberry ketones trigger a increase in the heart rate, which increases the supply of oxygen to the brain. This also increases the blood flow to skeletal muscles. This results in increase in the energy requirements of the body. In order to get the desired energy, the stored body fat is broken down into much simpler products. Therefore, this lipolytic act of norepinephrine results in body losing considerable fat in an easy and healthy way.

Raspberry ketones have a molecular structure which is identical to the synephrine (orange peeols) and capsaicin (chili peppers). Both of these compounds active a enzyime known as lipase which triggers rapid metabolism of body fats. Raspberry ketones ensure that the lipolysis process continues at a constant rate. This results in enhanced weight loss within a short time period.

Raspberry ketones also increase the production of T and B cells and thus play an important role in strengthening the immune system of the body. Aside from that, they also nourish the body with all essential micronutrients such as vitamin C, vitamin B, copper, magnesium, manganese and copper.

If you are interested in using raspberry ketones for losing excess weight, then you will find many exciting options on the market. Before buying a supplement or pills, you must ensure that it is made by a reputable manufacturer and comes at a reasonable price and has safe ingredients. Many sellers on the Internet offer exciting deals and you can easily order your requirements right from the comforts of your home.

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Date: August 04, 2009 01:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Resveratrol, Longevity, and Aging

Today growing older means more than settling into a comfortable armchair with the TV remote. Healthy aging means staying active and vigorous long into old age - not aging gracefully. An now intervention in the aging process - once regarded as fantasy - is within reach due to advances in nutritional science. One of the most exciting discoveries is resveratrol, a protective compound produced by grapes and other plants in response to environmental stress.

Stonger and more potent formulas are becoming available every day resveratrol included. One company Source Naturals has now produced a resveratrol product featuring 200 mg of pure resveratrol from traditional Chinese herb Hu Zhang (one of the richest sources) and from red wine extract.

A recent study at the Harvard Medical School reported that resveratrol triggers genes in mice that support longevity and metabolic balance. By stimulating SIRT I genes, it mimics the healthy aging benefits of caloric restriction. Resveratrol addresses the metabolic inflammation so prevalent in today’s society by inhibiting NF kappa-B and COX-2 enzymes. And it provides antioxidant protection to the cardiovascular and immune system. In fact, of the dozens of SystemiCare metabolic systems indentified by Source Naturals as necessary for optimal health, resveratrol positively affects five: cells/DNA; inflammation response; antioxidant defense; circulation; and immunity.

Have you given resveratrol a try? Staying healthy and living longer is appealing to all individuals who are climbing the age ladder.

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Date: April 13, 2009 03:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Detoxify With L-Citrulline

L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood.

It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea.

The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea.

The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-hydroxyarginine, and then into L-citrulline with the release of nitric oxide.

So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells.

Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred.

In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure.

Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery.

During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow.

It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels.

It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid?

Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise.

Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted.

Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.

L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.

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Detoxify At Vitanet ®, LLC

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Date: September 19, 2008 09:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ginkgo Biloba Extract

Ginkgo biloba, also known as the maidenhair tree, grows naturally in two small areas of Eastern China. It is believed that even these sources are artificial, and planted and maintained by monks over many centuries, and that there are no true natural sources of the tree left. Other than these, all living ginkgo trees are now artificially farmed.

The ginkgo seeds contain nuts that are a traditional food in China, served at Chinese New Year, and on other special occasions such as weddings, and is also used in traditional Chinese medicine. The seeds have been used in the treatment of coughs and asthma, and during the late 1970s and 80s, the uses of ginkgo biloba in medicine was extensively investigated with a view to determine the range of conditions that the tree could be used to treat. Given that many ancient Chinese remedies have found to be effective, and with a relevant scientific basis, this was a logical step.

It has been established that ginkgo biloba could have three possible effects on the body. These are:

* Improvement in circulation including that in the small capillaries.
* An antioxidant effect against free radicals.
* Prevention of some of the harmful effects of blood clotting and aggregation of platelets.

The last of these has been responsible for many cardiovascular conditions, and disorders of the kidneys, lungs and central nervous system, and is due to the effect of the platelet-activating factor (PAF) that ginkgo appears to inhibit.

Before delving deeper into the possible beneficial effects of Ginkgo, let us first examine the active ingredients believed to be involved in the perceived beneficial effects.

Ginkgo leaf extract contains terpenoids (bilobalides and ginkgolides) and flavonoid glycosides. Flavones can reduce the fragility of capillaries, and protect the body from blood loss through damaged capillaries, particularly in the brain. The Ginkgolides, particularly ginkgolide B, inhibit the platelet-activating factor and so increase the fluidity of the blood that improves circulation, again particularly in the micro-capillaries of the brain. This is also why it is believed to reduce the incidence of cerebral thrombosis and resultant strokes.

The antioxidant effect of ginkgo biloba extract (GBE) has been widely studied, and by scavenging free radicals the extract can help to prevent cell membrane damage, and so prevent cells from being destroyed. It has been established that pretreatment of cells with GBE can prevent such damage in rats.

The anti-inflammatory properties of ginkgo biloba, as seen in some asthma patients for example, is thought to be due to the inhibition of the platelet-activating factor (PAF) by ginkgolide B, PAF playing a significant part in the inflammatory response to allergens, and PAF is now believed to be responsible for conditions such as asthma, renal diseases, central nervous system disorders and ischemia, a restriction in the blood supply, particularly to the brain.

It follows, therefore, that the effect of GBE on these conditions is likely to be due to PAF inhibition, and a reduction in the inflammatory response to a number of conditions. What evidence is there for this? In fact, results of the trials carried out have been inconclusive one way or the other.

Hence, a trial published by the Journal of the American Medical Association reported no effects after a 6 week trial of Ginkgo on Alzheimer’s and memory disorders. However, other trials have indicated positive effects after 6 weeks, and it could be that the GBE has to be taken for more than 6 weeks for any effects to be noticed. It is certainly believed to be a longer term treatment rather than have instant results, although some tests have shown improvement in concentration for up to 2.5 hours after treatment. The bulk of the evidence is favorable on the effect of GBE on memory disorders.

Test on rats, in which the blood flow to the brain was mechanically blocked by carotid compression, indicated that ginkgo biloba promoted an increase in the glucose and ATP levels in the brain neurons. Other trials have indicated that neurological damage in mice subjected to neurotoxins was reduced by the administration of GBE, and while not conclusive with respect to humans, the effect of GBE on the brain appears to be more than just opinion.

To sum up, ginkgo biloba is believed to be effective in treating the following disorders by virtue of its effect in improving the fluidity of the blood, protecting fragile capillaries from damage, exerting an antioxidant effect on free radices, and so prevent damage to cell membranes, and its inhibiting effect on platelet-activating factor:

Circulation Problems

Circulation problems in the arteries can lead to blood clots that in turn cause strokes and cardiac problems. By preventing blood clots through the inhibition of PAF, ginkgolide B can help to maintain a healthy circulation system that also help to maintain circulation in the very small capillaries that feed the brain.

Atherosclerosis

This is caused by hardening and blockage of the arteries, and one of the effects of ginkgo biloba is to soften the arteries, help to unblock them and to prevent plaque formation by its antioxidant effect on the free radicals that cause the plaque by oxidation of LDL lipids. This is particularly true of the cerebral arteries.

Memory Impairment

The increased blood flow to the brain that GBE promotes can help to improve memory, although test are indicating that treatment has to continue for 6 weeks or more for it to be effective. Reduced blood flow to the brain is a common cause of memory impairment.

Alzheimer’s disease

Ginkgo biloba has been used in the treatment of the symptoms of this condition, although it cannot be cured. It is thought that the improved circulation in the brain makes best use of the unaffected brain cells, improving memory and cognitive thought.

Reynard’s Disease

This is a condition where the extremities fail to warm up after being exposed to cold, and is caused by poor circulation in the small capillaries in which the blood pressure is very low. They symptoms are numbness and pins and needles, and GBE helps to overcome this condition due to improvement in the circulation and protection of the capillaries by rendering them less fragile.

Vertigo

GBE can help to reduce the symptoms of vertigo such as nausea and dizziness. This is believed, once again, to be due to an improvement in blood circulation.

There are few doubts that ginkgo biloba extract improves the circulation, particularly in the micro-capillaries in the brain and extremities of the body, and also possesses antioxidant properties, both of which help to maintain and improve the memory, and that combined with its effect on the platelet-activating factor, most of the properties of GBE is due to its capacity to maintain and improve circulation, particularly through those blood vessels closest to the blood-brain barrier.


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Buy Ginkgo Biloba at Vitanet ®, LLC

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Date: April 25, 2008 02:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pinolenic Acid - Appetite Control

Mention "pine nuts" and peoples’ mouths are apt to start watering for a taste of garlicky pesto or fragrant pilaf. Ironically, the same ingredient that is so irresistible in gourmet cooking may help curb our out-of-control appetites. But only a particular variety of pine nut—Pinus koraiensis from Korea—will do.

Source Naturals PineSlim is a Korean pine nut oil (PinnoThin™). A small-scale study suggests that PineSlim may reduce feelings of hunger by increasing concentrations of appetite-suppressing hormones. The study also suggests that a feeling of fullness is experienced 30-60 minutes after taking PineSlim. For best results, PineSlim should be taken while following the Maximum Metabolism Weight Loss Plan™ enclosed in every bottle.

Enjoying good food is part of a healthy lifestyle, but too often we don’t know when to stop. PineSlim can help by addressing one of the most basic of the dozen deep metabolic systems identified by Source Naturals as critical to your optimal health: Hormones/Metabolism.

Less Calories for Improved Health

According to a National Health and Nutrition Examination Survey, an estimated 66% of U.S. adults are overweight. A normal body fat level is one of the factors associated with many markers of good health, including insulin efficiency, healthy inflammation response, good circulation, and normal cell regeneration. One of the best ways to achieve healthy weight is by curbing the amount of calories we take in—but that’s not always easy to do. Now an ancient Asian food source may help.

Korean Pine Nuts—Traditional Asian Food

The Korean pine nut (Pinus koraiensis) has been used as a food source for centuries and is often served as a snack at social events in China. Korean pine nuts grow on evergreen trees that produce seeds (commonly referred to as nuts) that are rich in oil, particularly oleic, linoleic, and pinolenic acids.

Pinolenic acid is a fatty acid, which may influence healthy blood pressure. According to recent research, pinolenic acid also may increase concentrations of the satiety hormones glucogon-like peptide-1 (GLP- 1) and cholecystokinin (CCK).

Appetite-Suppressing Hormones

Both GLP-1 and CCK are hormones that have been found to increase satiety and suppress appetite in normal-weight humans. They are believed to work by delaying gastric emptying. Retaining food in the stomach for a longer period of time may prolong a feeling of fullness.

In a randomized, double-blind trial, 18 overweight women received 3.00 grams of Korean pine nut oil (PinnoThin™)—the same amount as one daily dose of Pine Slim—or an olive oil placebo before a carbohydrate meal. Hormone measures of CCK and GLP-1 were taken from blood samples, and subjective measures of appetite were recorded. The study demonstrated a significant increase in appetite-suppressing CCK and GLP-1 hormones at 30-60 minutes after supplementation.

Your Source for Advanced Nutrition

The plant world offers an abundance of health promoting compounds. Today exciting discoveries are emerging from research into the health benefits of botanicals. The development of PineSlim reflects Source Naturals’ commitment to manufacturing supplements on the cutting edge of nutritional science. We are glad to partner with your local health food store in bringing you nutritional resources that help you take charge of your health.

References:

Causey JL (3/28/06) Korean Pine Nut Fatty Acids Induce Satiety-producing Hormone Release in Overweight Human Volunteers, American Chemical Society Abstract, “Health Benefits of Lipids” Symposium. ABSTRACT 0117: TECH-3.

Fontana L. (2006) Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 295(13): 1577-1578. Masoro EJ. (2005) Overview of caloric restriction and ageing. Mech Ageing Dev. 126: 913-922. Sugano M, Ikeda I, Wakamatse K, Oka T. (1994)

Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. British Journal of Nutrition. 72:775-783.

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Date: February 15, 2008 02:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Alpha Lipoic Acid is a Powerful Antioxidant

The discovery of alpha lipoic acid at the University Of Texas Chemistry Department in 1951 was not heralded with trumpets of joy at the revelation of such a powerful antioxidant, but was instead largely ignored. This is largely due to the biochemistry involved not being fully understood at that time, but by the 1980s it was a commonly used supplement, recommended for several medical conditions.

Chemically, the substance is a 5-membered cyclic disulphide with a carboxylic acid grouping. Biochemically, it’s extremely powerful antioxidant properties are largely due to the fact that it one of those rare active molecules that are soluble in both water and fats, and in fact is the only such antioxidant currently know. One of the properties that this ability enables it to possess is to cross the blood-brain barrier, and apply antioxidant propertied to the brain.

Antioxidants are essential to human life in that they destroy free radicals. These are compounds with free unpaired electrons that destroy human body cells in their hunt for electrons to pair with. Electrons come in pairs in organic animal tissue, just as they do in organic compounds. However, under certain circumstances this pairing can become destroyed, leaving a molecule with one of its electrons without a partner.

The factors that lead to this situation are many and varied, and our own biochemistry can produce free radicals during the normal chemical processes of life. However, pollution can also lead to the oxidation processes that create free radicals, common such pollutants being cigarette smoke, vehicle exhaust fumes, pesticides and the like. Excessive exposure to the UV content of sunlight can also create free radicals as can eating barbecued and smoked foods, and exposure to carbon monoxide and peroxides. Even the biochemical conversion of glucose to energy in our bodies creates free radicals.

These free radicals can destroy body cells, including DNA, and can create conditions such as premature aging due to destruction of skin cells, destruction of brain cells, strokes, cancers, diabetes, atherosclerosis due to oxidation of LDL cholesterol that deposits in the main arteries of the body, stiffening of the joints and many other undesirable conditions.

Free radicals are destroyed rapidly by antioxidants: the reaction is very rapid and most are destroyed immediately they are formed before they can do harm. Fortunately, if your diet is well maintained, the body possesses many antioxidants such as vitamins A, C and E, and other substances such as Coenzyme Q10, flavanoids, xanthenes, polyphenols and carotenoids. Many of these are found in highly colored foods, and if your food is brightly colored, it should contain a good supply of antioxidants.

However, the problem with all of these is that they are either fat and oil soluble or water soluble, which means that they can either be freely carried round the body by the blood or have to be emulsified by the bile and transported via the lymphatic system that places restrictions on their effectiveness in certain organs of the body. The fact that alpha lipoic acid is soluble in both water and fats enables it to be carried to all parts of the body and to every organ, and can cross water/fat barriers that other antioxidants cannot do.

It can therefore be carried via the blood to the brain and carry out an essential antioxidant function within our brains. It took a long time for this property of ALA to be recognized and its consequent health benefits understood. It is, in fact, the ideal antioxidant. The substance provides many known benefits to the body due to its antioxidant properties and also helps the body to generate the maximum possible amount of energy from the blood glucose and thus improve the energy balance of your body.

However, it is with its antioxidant properties that we are most concerned here. One of the benefits of these properties is its effect in holding back the visible effects of aging on your body. Because it is both water and fat soluble, alpha lipoic acid can help destroy free radicals in every part of your skin; the areas served by the blood and the fatty and oily secretions are protected simultaneously by the same strong antioxidant. The end result is a reduction in the destruction of the cells through the dermis and epidermis and a reduction in the degree of wrinkling with age.

Its antioxidant effect in the brain renders ALA in great demand for reducing cognitive impairment with age. In fact studies have indicated that alpha lipoic acid can improve memory and brain function in the aging and the elderly. This effect appears to be increased by the synergistic combination of alpha lipoic acid and acetyl-L-carnitine that work together to prevent cognitive decline in the brain through the effect of free radicals.

There is evidence that during a stroke, ALA works synergistically with vitamin E to reduce the effect of free radical damage on the vulnerable brain cells, and so reduce the longer term effects of the stroke. Together with ALC, it also reduces oxidative stress on the mitochondria of cells and in so doing helps once again to reduce the effects of aging, and maintain the body’s capacity to generate energy from blood glucose.

Cardiovascular disease is the main killer of the western world, largely due to our diets, and this is especially true of the USA. Although Americans appear unable to change their unhealthy diet, alpha lipoic acid and acetyl-L-carnitine can be used to offset much of the damage done. ALA reduces the development of atherosclerosis through its antioxidant properties and the reduction of the adhesion of monocytes to the artery walls.

LDL trapped in the wall of the artery can be oxidized and enable monocytes to also enter under the surface of the arterial wall, where it changes into macrophages and ingests the oxidised LDL, causing the plaque that forms atherosclerosis. As the plaque thickens, the artery becomes increasingly restricted until the blood flow is significantly reduced or even stopped, causing cardiac failure or a stroke.

Alpha lipoic acid can prevent this free radical oxidation from occurring by destroying them before they act on the low density lipoprotein (LDL). Acetyl-L-carnitine works with the ALA to achieve this, as does another substance known as carnosine. Between them, these three musketeers work to keep your arteries clear and your brain functioning as it should, though it is the ALA that is most powerful due to its oil and water solubility properties.

Although alpha lipoic acid is available as a supplement, either alone or in combination with acetyl-l-carnitine, it is also available from natural food sources. It is particularly rich in offal such as heart and kidney, and also in broccoli, spinach and brewer’s yeast. It is also available in beef, and it is here that burgers can perhaps repay some of the damage that it causes. However, it is not a recommended source since burgers still cause more damage to your health than any of their constituent nutrients can allay.

Like any other supplement, you should seek medical advice before taking any substance if you have a health condition. Nevertheless, the benefits of alpha lipoic acid are such that it is difficult to see it doing anything but good. However, please consult your physician if are taking other drugs.

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Date: January 02, 2008 02:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Big Pharma Plays God, Stealing and Altering Pant Compounds making Synthetic Drugs

It has been claimed by the Nutritional Health Alliance (NHA) that the pharmaceutical companies are formulating their pharma drugs using natural plant-derived substances. This is not totally groundbreaking news, of course, since the whole pharmaceutical industry was based on natural products such as aspirin, derived from willow bark, and antibiotics derived from the penicillin mold.

While there is nothing wrong with them doing this, there are signs of their increasing lobbying to limit the supply of supplements so that Big Pharma can monopolize the production and supply of all supplements and remedies, natural or synthetic. What is disturbing is that bills such as the Adverse Event Reporting Bill, passed by Congress in February 2007 as the Dietary Supplement and Nonprescription Drug Consumer Protection Act, could conceivably place greater powers into the hands of the large pharmaceutical companies to restrict the sales of natural products that are not part of their ‘approved’ prescription range.

This Act requires users and distributors of over the counter and non-prescriptive natural remedies to report any adverse effects that they believe have been caused by the remedy they are using. What this does is to require untrained people to make medical decisions as to what is causing their adverse reaction.

A patient taking several prescription drugs and a vitamin supplement might naturally assume that it is the vitamin that is causing their reaction, since they will believe the drugs to be safe. Hence they will report the vitamin supplement as being the cause. Since the act does not oblige them to report reactions from prescription drugs, then this opens the door for Big Pharma to hijack plant compounds, and then alter them to make synthetic drugs.

The position of the FDA in all of this is dubious since that body has already made many decisions that favor the large pharma companies rather than the consumer, or producers of herbal remedies.

However, there is also the opposite view that the supplement industry is unregulated, and some degree of control is long overdue. While it is difficult to argue against this, it is the form of control that is in question and also the reasons behind it.

The pharmaceutical companies have long gained through America’s ill health, and it is to their advantage for Americans to become ill or suffer from the chronic diseases that come with a sedentary lifestyle and a diet of fast foods. The industry’s short-sighted approach has been to wait until people become ill and then treated them with expensive drug, rather than prevention that would ultimate lose them customers for their products.

A happy and healthy community, regularly taking supplements that keep them fit and well, is not to the advantage of pharmaceutical companies that prefer a depressed, unfit and sick American population to which they can sell their products. Hence the smear campaigns in the press regarding ‘uncontrolled’ natural remedies, untold bills in Congress, and what could end up as the ultimate revocation of our freedom to consume the natural products of our choice.

If we are taking two or three prescription drugs for a heart condition or to reduce the cholesterol levels in our body, and also an Omega-3 fatty acids capsule, we are urged to report the capsule if we have any side effects from the cocktail. Presumably on the basis that the drugs have been approved by the FDA, and so cannot possibly cause any side effects in us. A fish oil capsule is hardly likely to cause a heart attack, but many prescription drugs can if badly prescribed. However, it is the capsule that is likely to be fingered, banned and then included in a pharmaceutical product that is cleared by the FDA.

Those that take over the counter supplements, vitamins and herbal remedies are a threat and it is difficult not to become cynical about the intentions of such Acts of Congress and the people behind them. True, the supplement and herbal industry probably does require some form of regulation, but to phrase this in such a way as to require medically untrained people to report what they perceive as being the adverse effects of supplements rings of an intention to regulate by restriction or even banning.

When that occurs, Big Pharma will take these products and fashion them into expensive prescriptive drugs that are then approved for use by the FDA. What we were at one time able to purchase from our local health store we would now have to purchase at several times the price through prescription.

The health benefits of natural nutritional supplements are well documented, and the industry are now using methods to ensure standardization of the active ingredients where possible. However, this is not always possible with foodstuffs that do not always grow in standardized ways.

The Dietary Supplement Health and Education Act (DSHEA) was passed by Congress in 1994 to protect and preserve our rights to healthy supplementation of our diets with natural products of our choice. The FDA has systematically failed to enforce this and prosecute synthetic manufacturers who have not kept to the law. The FDA does not need new powers, but the funding to implement those already in existence.

Lobbying in Congress by interested parties should not be allowed to undermine the rights of all Americans of the freedom to consume the products that will provide them with a healthier lifestyle. The DHSEA is all that is needed to preserve this and to protect consumers from Big Pharma and their need to create conditions conducive to an increasing need for their products.

Yes, the health supplements industry likely needs some form of regulation to ensure standardization of products as far as is possible, but the way to do this is not to place medical decisions into the hands of the untrained. Do not forget that these are natural products, available freely from nature in fruit, vegetable and animal products, and are not synthesized in a laboratory as many of today’s drugs are.

However, give them a free rein, and Big Pharma will hijack these natural products, change them and then sell them to us at highly inflated prices to do the job that already do for us: keep us healthy.

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Vitanet, LLC ®

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Date: May 28, 2007 11:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Extended existence?

Humankind has long searched for a special elixir that would confer immortality…or, failing that, at least prolong youthful vitality for a decent number of years. Resveratrol is no magic potion, but it has improved survival rates among mice at the ripe old age (for a mouse) of 114 weeks even overweight mice fed high-calorie chow (Nature online 11/1/06). What’s more the Resveratrol bolstered rodents stayed fit and trim well into their senior years; as Dr. Rafael de Cabo of the National Institute on Aging told the news service heartwire, such a finding “suggests that this compound may not just extend life but may also enable individuals to lead healthy and functional lives for longer.”

While tests continue on how Resveratrol could produce these results, it is believed that this substance may actually mimic the effects of calories restriction, which has been shown to increase longevity. Resveratrol apparently activates a gene known as SIRT1 activation is also associated with greater exercise capacity and fat burning.) in addition, Resveratrol both acts as an antioxidant itself by mopping up dangerous molecules called free radicals and helps enhance the antioxidant effects of vitamin C and E.

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Date: December 15, 2006 04:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Controlling Diabetes with Nutritional Supplements

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Date: December 11, 2006 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Red Wine Extract with Resveratrol - Powerful Antioxidant Protection

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Date: June 19, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The healing power of borage oil

Borage oil, extracted from the seed of the blue, star shaped borage flower, is gaining much attention by alternative health practitioners and main stream medicine alike for its profound medicinal properties. Whereas the oil is getting all the redit, it is actually the oil’s active component, gamma linoleic acid (GLA), which has drawn the interest of researchers. The majority of the early studies done on GLA, dating back to the late 1940’s, were conducted with the oil of evening primrose. For rezones cited in the title, more bank for the buck, borage seed oil is now thought to be s superior source of GLA compared to evening primrose oil. Other plants forms and food concentrates that contain appreciable amounts of GLA include black currant seed oil and spirulina.

Why GLA Supplementation?

A body with healthy biochemistry has the ability to produce GLA from the most essential fat linoleic acid. Linoleic acid is found most abundantly in the omega 6 family of oils, including safflower, sunflower, and corn oil. While it has been estimated that a majority of Americans and Europeans consume far to many omega 6 fatty acids in proportion to the beneficial omega 3 fatty acids (by approximately 10:1). Most biochemists agree optimal ratio of omega 6 to omega 3 fatty acids should be approximately 1:1. Despite the obvious over consumption of omega 6 oils rich in linoleic acid, some individuals lack the ability to convert linoleic acid to the much needed GLA.

As is the example with many of our modern day nutrient deficiencies, the adulteration of our food supply by today’s processing methods has much to do with the faulty fat metabolism suffered by many. A prime example is the hydrogenation process utilized to convert liquid polyunsaturated oils into semi-solid, altered saturated fats for use as margarine and commercially processed foods. Hydrogenation is accomplished by subjecting the oils to temperatures in excess of 250 C, and bombarding them with hydrogen ions in the presence of the heavy metal nickel, which irreversibly changes the chemical structure of the fatty acid molecule from a healthful “cis” configuration to a dangerous “trans” configuration. When these products are eaten in excess they are known, in some cases, to block the enzymatic conversion of linoleic acid to GLA. In addition to the damaging effects of hydrogenation, certain essential fatty acid nutrient cofactor deficiencies may exist to further complicate the conversion. Vitamins pro-A, A, C, E, B-2, B-3, B-6, pantothenic acid, B-12 biotin and the minerals calcium, magnesium, potassium, sulfur and zinc are all involved in essential fatty acid (EFA) metabolism.

Particular interest should be given to those afflicted with diabetes, cystic fibrosis, asthma, alcoholism, multiple sclerosis. For a myriad of reasons, including cofactor deficiencies, these individuals lack the enzymatic ability to convert linoleic acid to GLA and must obtain a direct source of GLA for proper hormonal regulation. In addition, excessive consumption of animal fats containing acachidonic acid competes for the same metabolic pathways occupied by GLA, thus minimizing its biological action.

These potential negating effects can simply be diverted to consuming a food source or supplement containing GLA which bypasses any previously necessary enzymatic conversion and floods the metabolic pathways with beneficial GLA. Nutrient deficiency should also be addressed. Here lies the true power of GLA.

Prostaglandins, biochemical regulators

Whereas GLA is the power, the prostaglandins deliver the punch in this biological equation. Just as linoleic acid is normally converted to GLA, GLA is further converted into the prostaglandin E1 (PGE1). Many of the benefits derived from GLA supplementation are a result of the hormonal regulatory action of the prostaglandins. Just like the “parent” precursors they are made from, the hormone-like prostaglandins orchestrate a host of important biochemical activities. Their general regulatory effects include the control of arterial muscle tone, sodium excretion through the kidneys, blood platelet “Stickiness,” inflammatory response and the immune function, just to name a few. The list may be endless as scientists continue to discover the regulating effects of prostaglandins. One way in which GLA has shown to decrease the probability of allergic and inflammatory conditions is by competing with arachidomic acid, which when left unchecked may potentiate a hyperimmune response.

Healing Power

As a result of the powerful regulating effects derived from the conversion of GLA to healthful prostaglandins, borage oil and other GLA supplements have shown to be beneficial in the treatment and relief of many classic and modern day health problems. The disease of diabetes, cystic fibrosis, asthma, multiple sclerosis are thought to be helped by bringing about a balance in an otherwise faulty fatty acid metabolism. According to a study released in the journal diabetes care, supplementation with GLA has shown promise in the reversal of diabetic neuropathy (a condition where the nerves degenerate and symptoms of pain and numbness follow). The study concluded that all diabetics should be considered for dietary protocol of GLA. Other conditions shown to benefit include high blood pressure, high cholesterol, skin conditions, arthritis, allergies, weight loss, improved behavior of hyperactive children and increased strength of hair and nails. Cited in the book, Super Nutrition For Menopause, written by the renowned nutritionist Ann Louise Gittleman, is one of the most popular applications of GLA supplementation in the relief of menstrual pain. Sufferers use a maintenance does up to the seventh day prior to menstruation, then double the dose for the duration of their menstruation. Dietary restrictions of meat, dairy and eggs during this time has also shown to compliment this regiment. Many would agree with Ms. Gittleman’s credo in allowing mother nature to cure our ails before relying on synthetic drugs which often come with side effects.

More Bang for the Buck

Now comes the challenge of acquiring a GLA supplement suited to meet your needs. With the help of the information below you may maximize your desired result while at the same time stretching your dollars. Lets take a look at the facts. We will limit out narrative to the tree most popular forms of GLA supplementation: 1) borage oil, 2) evening primrose oil and 3) black current seed oil. Potency is an important factor, as the higher the GLA content per gram, the more likelihood of greater biological activity. Borage oil contains 24% GLA, or 240mg per 1000 mg capsules. Black current seed oil contains 18%, or 180mg per 1000 mg capsule and evening primrose oil contains 10% GLA, or 100mg per 1000 mg capsule. While black currant seed may appear to run a close second to borage and have a slight edge on evening primrose, it contains a potent GLA inhibitor and should be considered last on the list. equally, if not more important than potency, is purity. Make it a practice not to purchase any oil product unless full disclosure of the method of extraction is printed on the label. If it is not, you may assume that the oil has been extracted in one of the following ways. Unfortunately, the popular use of the chemical hexane to extract oils is not required for disclosure. This method employs submerging cracked seed in a gasoline like substance (Hexane) and then slowly allowing it to evaporate off yielding 90% oil recovery. This is the most common method used to extract evening primrose oil because of the incredibly small, hard seed and low oil content. The second creative ploy is the claim that the oil has simply been extracted by a new high-tech method called supercritical fluid extraction (SCFE). This process “pregrinds” the seeds then subjects them to pressures of 6000 – 10000 psi in the presence of the gas CO-2. Under such intense pressure CO-2 gas becomes a liquid in which the seeds are submerged, ultimately yielding a 95% oil recovery. Look for oils that are labeled as “expeller pressed” without the damaging effects of light, heat and oxygen. The products should be contained in opaque (light resistant) bottles to protect them from the damaging effects of light. Optimally, you should find them in the refrigerated section of your local health food store. Due to the higher percentage of oil contained in the borage seed, as compared to evening primrose and black current, borage is typically priced well below the others making it the most potent and economical choice. All things considered an expeller pressed borage oil, contained in an opaque plastic bottle, may provide you the absolute best source of unadulterated GLA supplementation.

One company that provides such a product and always fulfills the quality requirements listed is Barlean’s Organic Oils. Their organic flax oil and borage oils are available at VitaNet.

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Buy Barlean's Organic Oils at Vitanet

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Date: December 12, 2005 09:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Court Rules for FDA in Lane Labs Appeal

A federal appeals court has ruled that Lane Labs (Allendale,NJ) may be ordered to pay back consumers for selling what the food and drug administration (FDA) considered unapproved new drugs. The three-judge panel upheld the 2004 decision by U.S. district Judge William G. Bassler of the District of New Jersey, which stated that FDA may demand that Lane Labs pay back every consumer who had bought the company’s top selling products—shark cartilage supplements that were allegedly marketed as treatments for diseases including cancer and HIV. The restitution amount is estimated at 109 million. The appeals court rejected the argument that FDA cannot demand restrictions because the Federal Food, Drug, & Cosmetic Act (FDCA) does not expressly provide for such a remedy. “Whether or not congress specifically contemplated restitution under the FDCA, the ability to order this remedy is within the broad equitable power granted to the district courts to further the economic protection purposes of the statute,” 3rd Circuit Judge Marjorie O. Rendell wrote in an opinion joined by Judges Maryanne Trump Barry and Edward R. Becker.

In its appeal, Lane Labs was supported by an amicus brief from the Washington Legal Foundation (WLF, Washington, DC) urging the court to reverse Bassler’s decision, on the grounds that restitution is not authorized anywhere in the text of the FDCA.

WLF attorneys Daniel J. Popeo and Richard A. Samp, joined by attorney Jeffrey A Lamken of Baker Botts in Washington, DC, argued that the FDCA gives courts the power to “restrain” violations, but does not allow FDA to seek “Backward-looking monetary relief.”

WLF argued that FDA, throughout most of its history, never asserted a right to seek restitution until recently, when it began asserting that power in order to have “a big club with which to intimidate manufacturers who might otherwise seek to challenge FDA directives,” including large pharmaceutical companies. However, the court upheld FDA’s authority to seek restitution on the grounds that the FDCA’s grant of authority to restrain violations of the Act should be read broadly to include all forms of equitable relief.

FDA cannot be allowed to get away with this power grab,” said Samp after reviewing the Third Circuit’s decision. “The American economy suffers, and public safety and health are jeopardized, when FDA seeks to exert power beyond its authority, upsetting to delicate balance struck by Congress in its attempt to both preserve the public welfare and encourage valuable pharmaceutical innovations.” He added that WLF has pledged to continue to litigate the issue and to support Lane Labs in any further appeals the company may file.

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Date: July 15, 2005 12:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CONCLUSION

CONCLUSION

If you fall into the category of a consumer who is searching for an excellent natural sweetening agent which is safe, powerful, and calorie-free, stevia extracts should be first on your list. Ironically, while enormous quantities of aspartame and saccharine continue to be consumed in this country, a sweetening substance that poses less risk and is more effective continues to be rigorously regulated. Fortunately, restrictions are easing and it is now possible to purchase stevia as a supplement. Both xylitol and saccharine have been linked to tumor development and aspartame continues to prompt controversy in its reported wide range of negative side effects, yet all of these products enjoy unrestricted marketability. It is rather ironic that chemical compounds that have the capability of wreaking all kinds of havoc with human physiology have the advantage over natural substances that are certainly much more benign. It’s hard to imagine that a safe, natural herb which offers concentrated sweetening power and may also actually normalize blood sugar and pre vent tooth decay remains relatively unknown.

Stevia will inevitably emerge as one of the best non-caloric sweeteners available. It’s just a matter of time before American consumers discover its extraordinary attributes. In the meantime, learning to use stevia dietary supplements can provide us with the ability to “sweeten” our lives without compromising our health. (NOTE: Linda Bonvie, Bill Bonvie and Donna Gates have written a comprehensive and engaging book on stevia called The Stevia Story. They have done extensive research and have put together a well written treatise on the subject. In addition, there are over fourteen current clinical studies on stevia listed in Medline which discuss various biochemical attributes of the herb’s glycosides.)

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Date: July 07, 2005 04:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Sugar Overload....

Sugar Overload

My kids are getting completely overloaded on sugar at school from meals and treats -- my daughter comes unglued and cant study. When i went to grade school, there was no lunch and no sweets available. What a change in society... Amanda Shrewsbury - Spring City, Utah...

You're right to be concerned about school food programs, especially since budget restrictions have led a number of districts to use major fast-food companies as food service providers -- and even worse, to let soda companies stock school beverage machines.

Fortunately, the tide is starting to turn. Los Angeles is just one of a number of cities that are banning soda from their school buildings. Other districts are going so far as to offer organic lunches to there students. you may want to contact your school superintendent, as well as members of your local school board and let them know how you feel about what's best for your children.

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Vitanet ®

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Date: June 29, 2005 10:39 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: LIFE FORCE MULTIPLE - Essential Nutrients to Support Your Low Carb Lifestyle..

Life Force Multiple

Taking care of your body is an especially important challenge in today’s stressful and hectic world. Choosing a low carb lifestyle is an increasingly popular way to seek better health. In fact, there are approximately 30 million U.S. adults counting their carbs right now. While effective for weight control and therefore having positive health effects, low carb approaches can also result in serious nutrient imbalances. Thus, adding the right multiple to your low carb approach is an enormously important next step for your good health. LIFE FORCE MULTIPLE, the top-ranked and award–winning multiple from Source Naturals, replenishes these nutrients and provides compounds that will help your body process the increased proteins and fats better while you are restricting carbs.

Low Carb Benefits

Restricting carbs can have many health benefits. And lowering your intake of refined simple carbs, such as sugar and white flour, can help you promote healthy blood sugar and insulin levels, which is critical for your good health. Insulin is used to move the glucose from carbs into your cells for energy. Ingesting too many refined carbs can greatly reduce your body’s ability to use insulin well, which can lead to short and long-term health concerns.

Replenish Nutrients with LIFE FORCE

LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient dense foods such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including beta-carotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products such as calcium, potassium, vitamin A and vitamin D.

Support Healthy Fat and Protein Consumption with Life Force

Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, N-Acetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.

Restricting simple carbs can do much more than help you maintain a healthy weight; it can also be the foundation for maintaining good health throughout your long life. But you need to develop a thoughtful holistic strategy for success. When you integrate LIFE FORCE MULTIPLE into your wellness plan, then you can benefit from decades of clinical research about the nutrients your body needs to support optimal health and a low carb lifestyle, long before this information becomes part of mainstream health recommendations. Join this wellness revolution by adding LIFE FORCE to your strategies for health and allow yourself to start feeling energized today!

References
Marchione, M. (2004). Eating Lots of Carbs May Raise Cancer Risk. Associated Pres. Available at com/news?tmpl=story&u= /ap/20040806/ap_on_he_me/fit_cancer___carbs . Warner, J. (2004). Have We Gone Carb Crazy? Experts Clear Up the Confusion Over the Low-Carb Craze. WebMD. Available at ent/ Article/83/97595.htm?pagenumber=2 . Whitney, E. N., et al. (1998). Understanding Normal and Clinical Nutrition. Wadsworth Publishing Company, Belmont, CA. 325-484.

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Vitanet ®

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Date: June 29, 2005 10:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Life Force - The Energy Activator

Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%

We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.

Bio-Align™ Yourself with Life Force

LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.

Get Ahead with Activated Energy and a Healthy Metabolism

Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.

LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.

Protect Your Heart and Circulatory System

The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.

Skin and Musculoskeletal Support

LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.

Brain and Nerves Nutrition

The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.

Immune Defense

LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.

Powerful Liver Support

Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.

Complete Antioxidant Defense

Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.

Cutting-Edge Vision Nutrition

The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.

Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle

LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.

Support Healthy Fat and Protein Consumption with Life Force

Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.

Complete Energizing Nutrition

LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!

References
Guyton, A. 1991. Textbook of Medical Physiology, Eighth Ed. W.B. Saunders Co., Philadelphia, PA. Halliwell, B. and Gutteridge, J. 1995. Free Radicals in Biology and Medicine. Clarendon Press, Oxford. Linder, M. 1991. Nutritional Biochemistry and Metabolism, Second Ed. Appleton and Lange, Norwalk, CT. Mathews, C. and van Holde, K.E. 1990. Biochemistry. The Benjamin Cummings Publishing Co., Inc. Shils, M. and Young, V. 1980. Modern Nutrition in Health and Disease, Sixth Ed. Lea & Febiger, Philadelphia, PA.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=520)

Date: June 25, 2005 10:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GARLIC AND CHOLESTEROL LEVELS

GARLIC AND CHOLESTEROL LEVELS

Several controlled studies have conclusively proven Garlic’s ability to lower blood serum cholesterol levels.6 Dozens of these studies conducted throughout the world have compared high fat diets with garlic and without and their resulting cholesterol counts. When Garlic is consistently consumed, the lowest cholesterol levels are obtained.7

Apparently, the allicin compounds in garlic help to block the creation of cholesterol. Consequently, serum-triglycerides and betalipoprotein levels were lowered while HDL levels (good cholesterol) were raised. The way in which garlic accomplished this specific action is not totally understood. What is known is that the presence of Garlic provides a simple restriction in the rise of blood cholesterol and lipid levels.

For anyone with a tendency to develop atherosclerosis, these findings are highly significant. When administered in therapeutic dosages, garlic protected the arteries against atherosclerotic lesions. The implications of studies such as this one are that ingesting garlic on a regular basis may have significant value for anyone suffering from heart disease due to hardening of the arteries. Garlic clearly suppresses cholesterol synthesis in the liver by lowering total serum cholesterol. It appears to accomplish this by inhibiting the synthesis of harmful LDL cholesterol which boosts the amount of beneficial HDL cholesterol in the blood. An added bonus of garlic is that some of its chemical components also keep the liver from producing its own cholesterol.8 Laboratory rats whose diets were supple-mented with garlic not only had fewer lipids in their blood and tissue samples, but less cholesterol and triglycerides in their livers as well. Interestingly, the sugar factor plays a role in cholesterol production and garlic can also be of benefit here. Excess sugar is metabolized into materials which are required for the making of cholesterol and other fats. If the diet is high in sugar, triglycerides levels can rise.

Tests have shown that when diets high in fat and sugar were supplemented with garlic, the expected rise in blood lipids did not occur.9 Apparently, in some of these tests, aged Garlic extract was the most effective form. Interestingly, in some studies, blood lipids initially rose after taking garlic and then declined. It is believed that because garlic removed fats that were deposited in the tissues into the bloodstream, lipid levels rose temporarily, however, the garlic also helped to metabolize those fats and excrete them from the body.10 Extensive data strongly suggests that garlic is of great value in both the prevention and treatment of cardiovascular disease which is a result of arterial fatty deposits. Using garlic can decrease the phospholipid content of the blood even when the diet is high in saturated fat. This particular action is nothing less than extraordinary. Garlic’s ability to affect a significant reduction in cholesterol appears to be dose-dependent. In other words, the more garlic consumed, the greater the results. Epidemiological studies support this fact and have shown an inverse correlation between cardiovascular disease and garlic consumption in various populations worldwide.11

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Date: June 21, 2005 05:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Keto - The Key to Healthy Aging

7-Keto " The Key to Healthy Aging

The global population is aging at an alarming rate and causing an explosion in health care costs, insurance premiums, cosmetic surgery and more. In the U.S. alone, more than one million baby boomers are expected to live to 100 years of age or older. This increased life expectancy presents a whole new set of health concerns that the medical community has not had time to address, since there is a greater need to care for age-related health problems in this ever-growing elderly population.1

Aging and the Decline in Vital Nutrients

We all grow old at the same rate but people age at different rates. Aging is a process of gradual changes that occur to varying degrees in each of us. Interestingly, the aging process is composed of different components and interactions, some of which can be impacted. One such component is the declining level of essential biological compounds, which causes our bodily functions to slow and become dysfunctional. Our organs don?t work efficiently, our immune system becomes lazy, we lack energy, our metabolism drops and we gain weight easily.1 7-oxo DHEA (7-Keto™) is a naturally occurring compound that declines with age.2 Replacing this key metabolite helps promote a healthy immune system and maintains resting metabolic rate at levels that accelerate weight loss during standard weight reduction programs.

Aging and a Healthy Immune System

Numerous changes occur in the immune system with advancing age, probably contributing to decreased immune responsiveness. Although all segments of the immune system are affected, investigators have most consistently identified declines in cellular or T-cell mediated immune function in the elderly. The decline in T-cell immune function is generally associated with an increased susceptibility to foreign organisms. For example, individuals with age-related declines in cellular immunity have an impaired response to vaccinations, making them more susceptible to health imbalances even though they have had their shots. In a clinical study presented at the Federation of American Societies for Experimental Biology meeting in April 2004, the effect of 7-Keto on elderly immune function was evaluated. Healthy elderly adults were given 7-Keto orally twice daily over a period of one month. The study revealed that 7-Keto augmented several key T-cell mediated immune function parameters compared to placebo administration.4

Age-Related Weight Gain

Age-related weight gain and obesity are approaching epidemic proportions in our country.5 Weight gain is a disorder of energy balance involving energy intake and/or expenditure. Low energy expenditure, a drop in resting metabolic rate (RMR), is a challenge during most weight loss attempts due to age, calorie restriction, lack of physical activity or a combination of factors. RMR represents 60% of total daily energy expenditure. Maintaining a higher RMR as we age and during weight reduction programs helps us achieve and maintain a normal weight. Furthermore, compounds with the thermogenic potential to achieve even minimal increases in daily energy expenditure of 2-3% may have clinical relevance in preventing the decline in RMR with calorie restricted diets or weight loss, and in decreasing the risk of regaining weight. 7-Keto, a non-stimulant thermogenic compound, has been shown to significantly increase energy expenditure in humans.6 A recently completed clinical study, also presented at the Federation of American Societies for Experimental Biology 2004 meeting, revealed that administration of 7-Keto to overweight adults in conjunction with a calorie restricted diet effectively reversed the decline in RMR normally associated with dieting. Obese participants following a calorie-restricted diet demonstrated a 5.4% increase in daily RMR with 7-Keto.7 The magnitude of the increase in RMR by 7-Keto is clinically relevant, and represents a promising agent for enhancing thermogenesis and weight loss in obese individuals on calorie-restricted diets. Additionally, 7-Keto has been shown in two confirmatory published clinical studies to result in three times more weight loss compared to diet and exercise alone. It has a favorable side effect profile and is easy and convenient to take.8,9 Our life expectancies will likely be longer than those of our parents, and our quality of life during those years will depend on how well we take care of our bodies now. Undoubtedly, the science of aging will give rise to new and exciting technologies to help us age more gracefully and healthfully. Maintenance of healthy immune function is keenly needed for improved quality of life in the elderly. Dietary manipulation and supplementation has been identified as a method of immune system renewal, and supplements such as 7-Keto may play an important future role as immune system modulators. Moreover, the addition of 7-Keto to any weight loss program will offer vital support of energy expenditure and help with the attainment of a manageable and healthy weight into our older years.

References

1. 1995 White House Conference on Aging, ?Executive Summary: The Road to an Aging Policy for the 21st Century," February 1996: 17-18. 2. Marenich LP. Secretion of Testosterone, Epitestosterone, Androstenedione, and 7-Keto-Dehydroepiandrosterone in Healthy Men of Different Ages. Prob Endokrinol. 1979; 25(4): 28-31. 3. Ginaldi L, De Martinis M, D?Ostilio A, Marini L, Loreto MF, Quaglino D. Immunological Changes in the Elderly. Aging 1999; 11(5): 281-286. 4. Zenk JL, Kuskowski MA. The Use of 3-acetyl-7-oxo-dehydroepiandrosterone for Augmenting Immune Response in the Elderly, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 5. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and Trends in Obesity Among US Adults. 1999-2000. JAMA 2002;288:1723-1727. 6. Astrup A. Thermogenic Drugs as a Strategy for Treatment of Obesity. Endocrine 2000;13(2):207-212. 7. Zenk JL, Leikam SA, Kassen LJ, Kuskowski MA. A Prospective, Randomized, Double Blind Study to Evaluate the Effect of HUM5007 and 7-oxo DHEA on Resting Metabolic Rate in Overweight Adult Men and Women on a Calorie Restricted Diet, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 8. Kalman DS, Colker CM, Swain MA, Torina GC, Shi Q. A Randomized, Double-Blind, Placebo Controlled Study of 3-Acetyl-7-Oxo-Dehydroepiandrosterone in Healthy Overweight Adults. Current Therapeutic Research 2000;61: 435-442. 9. Zenk JL, Helmer TR, Kassen LJ, Kuslowski MA. The Effect of 7-Keto Naturalean on Weight Loss: A Randomized, Double-Blind, Placebo-Controlled Trial. Current Therapeutic Research 2002; 63:263-272.

John L. Zenk, M.D., is Chief Medical and Scientific Officer for Humanetics Corporation and President and Medical Director of Minnesota Applied Research Center, both located in Eden Prairie, MN. He has spoken nationally and internationally on the subjects of integrating conventional and complementary medicine, anti-aging technologies, evaluating the effectiveness of alternative medicine, and dietary supplement research and development. He is author of the book Living Longer in the Boomer Age, and co-author of the book Age Wise and is a frequent contributor to national media. He has served as Principal Investigator for 15 controlled clinical studies, three of which were recently published in national peer-reviewed journals, and has presented abstracts at the 11th World Congress for Food Science and Technology and the Federation of American Societies for Experimental Biology.

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Vitanet ®

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Date: June 18, 2005 09:07 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Anti-Aging Nutrients

Anti-Aging Nutrients by Edward C. Wallace, DC, ND Energy Times, February 3, 2000

What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful, easy feeling.

How Do We Age?

Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.

The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.

Programmed Cell Theory

In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.

Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.

Free Radical/Oxidative Stress Theory

The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents.

Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.

DNA Repair Theory

Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.

What Can We Do?

The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.

In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."

Antioxidant Protection

Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.

Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.

In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.

Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.

Nutrition Deficiencies

A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).

When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).

A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.

Longevity Diets

A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460).

Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers (Epidemiology 3[5], 1992: 389-391).

Staying Alive

Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.

Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).

In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.

Longevity and Exercise

Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.

Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.

The Treadmill of Life

The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying (JAMA 273 [14], April 12, 1995: 1093-1098).

Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.

Longevity Supplementation

Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.

Toning Down Enzymes

Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).

In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.

The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).

Vitamins E & C

A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.

Chronological Age Vs.Biological Age

Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems.

In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.

Similar Relationship

A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less.

And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.

The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).

Carotenoids

When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.

Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119[1], Jan. 1989: 112-115).

Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.

Flavonoids

Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.

Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).

Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.

Amino Acid Health

Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.

Attitude & Behavior

Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).

In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).

Longevity at Last

While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of longer life. And by staying healthier, your old age will be more enjoyable, too.

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Vitanet ®

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Date: June 14, 2005 05:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Energize Your Life!

Energize Your Life!

by Laura Weiss Energy Times, December 1, 2003

If every fatigued day leaves you wondering where your energy went, you need a personal energy makeover.

"Energy, some special kind of energy, just leaks out and I am left lacking the confidence even to cross the street," Diane Arbus, the photographer, once complained. And while Ms. Arbus tried to overcome her energetic and spiritual ups and downs with her art, you can use lifestyle changes as well as self-expression to revive your vigor.

To Sleep, Perchance to Energize

When you're looking for a boost in personal energy, you've got to get enough sleep, insists Jacob Tietelbaum, MD, author of From Fatigued to Fantastic! (Avery). Dr. Teitelbaum emphasizes that unless you "give your body eight to nine hours of sleep per night," your personal energy will never be adequate.

Studies show that getting less than six hours sleep a night hurts your mental performance and drains your energy (Sleep 3/15/03). As your sleep debt builds up, your energy drops down.

"[Our studies show] the importance of sleep as a necessity for health and well-being. Even relatively moderate sleep restriction, if it is sustained night after night, can seriously impair our neurobiological functioning," says Hans P.A. Van Dongen, PhD, Assistant Professor of Sleep and Chronobiology at Penn State.

A recent poll by the National Sleep Foundation found that Americans, on average, are getting less than seven hours of shuteye a night. That sleep deficit drains energy.

Watered Down Energy

Added to that sleep requirement, Dr. Teitelbaum stressed in an interview with Energy Times, a lack of water can deplete your personal energy.

"The number one problem is often dehydration," he says. "Make sure you stay hydrated. Although I think it's a bad idea to [obsessively] count glasses of water, you should carry a bottle of water with you, check your lips and if they feel dry drink more water." Overall, your body is about 60% water and 70% of your muscles consist of water. If you let your water levels dip too low, your muscles suffer and your energy levels dip as well. Research shows that as your body dries out, your mental processes can slow down. And the hotter the temperature, the more fluid you may lose (AIHAJ 2002; 63(2):190-8).

B Vitamins for Energy

Also important for keeping your energy up "is getting enough of the B vitamins and magnesium." And even though Dr. Teitelbaum advocates the necessity of a well-rounded multiple vitamin and mineral supplement plus an adequate diet and amino acids to get all the nutrients you need, he recommends "taking a high-level B complex. The RDAs (the government's Recommended Daily Amounts) are inadequate."

In the body, B vitamins are used for the production of energy on a cellular level. For instance, vitamin B1 (thiamine) is crucial for burning carbohydrates effectively. And vitamin B6 (pyridoxine) is necessary for the body's ability to properly use B1. At the same time, vitamin B12 (cobalamin) is required for proper nerve function. The need for B12 may necessitate a supplement: Up to 30% of everyone over the age of 50 may have trouble absorbing B12 from their food (Crit Rev Clin Lab Sci 1996; 33:247). Plus, since vegetables contain very little absorbable B12, vegetarians of all ages may also require B12 supplements.

Dr. Teitelbaum also believes that taking malic acid, a nutrient derived from apples, can help. Along with the B vitamins, malic acid is used by the body in the production of energy. When taken with magnesium, malic acid has been shown to ease the pain of fibromyalgia (J Rheum 1995; 22(5):953-7), a condition characterized by fatigue and lack of energy accompanied by painful muscles and joints.

Ginseng Boost

Asian ginseng (Panax ginseng) represents a potential tool for controlling blood sugar and improving stamina.

According to Dr. Teitelbaum, "...Asian ginseng enhances energy, raises blood pressure and improves adrenal function...Asian ginseng has such a wide mix of health benefits that its name, Panax, comes from the Greek roots of pan (meaning 'all') and akos (meaning 'cure')-that is, 'cure all.'"

Research on people with diabetes shows that this herb may help control blood sugar levels. People who suffer what is called type 2 diabetes often eat small meals to keep their blood sugar from varying too much. (Rising and falling blood sugar can drain you of energy as well as make diabetic problems worse.)

An investigation of how another form of ginseng, American ginseng (Panax quinquefolius), affects blood sugar after eating found that it tempered changes by up to 20% (Arch of Internal Med 4/00). These scientists found that folks with diabetes did best when they took the herb within two hours of a meal.

Ready to re-energize? Time to stop skimping on sleep and rushing through inadequate meals. For all of us, slowing down and giving our bodies a chance to regenerate its zip can make the big energy difference.

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Vitanet ®

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Date: June 14, 2005 11:50 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Marilu Henner: Energy Personified!

Marilu Henner: Energy Personified! by Stephen Hanks Energy Times, January 3, 2005

Marilu Henner is an actress, dancer and author, a health, fitness and cooking guru and a devoted mom. Now she's also an advocate for nutritional supplements. In this revealing interview, she offers her thoughts on the battle to support consumer rights and to create a better health care system in America.

"So, you want to know what my schedule is after I finish talking with you?" Marilu Henner says, in an almost breathless voice. "Today's Tuesday, right? Tomorrow morning I leave Los Angeles [where she lives] for New York City so I can do the Tony Danza Show first thing Thursday morning, Then, I take a 9 am flight back to LA because my son has a sleepover birthday party. I have a 7 am flight to New Jersey the next morning because I'm speaking about mental health at a conference at a big country club. The next morning, I catch a 7 am flight back to LA for my son's soccer games, one at noon and the other at 2. Whew!"

Trying to keep up with Marilu Henner would make anybody feel out of breath because the woman is energy personified. At 52, her schedule includes acting in movies, on television and in the occasional Broadway show, writing books (she's authored seven, including Total Health Makeover and Healthy Life Kitchen), teaching online diet and exercise classes through her website (marilu.com), taking Pilates classes three times a week and raising two sons, Nicholas (10) and Joseph (8).

But now, on top of all that, the former star of the TV show Taxi has become a health and nutrition activist, speaking out in favor of the use of dietary supplements whenever she can. This past September, Henner testified at a hearing of the House Subcommittee for Human Rights and Wellness to advocate increased funding for research and full implementation of the Dietary Supplement Health and Education Act (DSHEA). During her testimony, Marilu described why she believes consumers should have access to more information about supplements and why the products should be made more accessible through both government initiatives and private health plans. "I believe that dietary supplements should be part of a campaign to improve our nation's health," Henner testified.

Energy Times recently caught up with Marilu at her Los Angeles home for a freewheeling conversation. Here, this vibrant yet down-to-earth celebrity displays her passion for health, nutrition and consumer issues.

Energy Times: You've become one of the most high profile celebrities to advocate a consumer's use of dietary supplements. What was your motivation to get involved in such a public way?

Marilu Henner: As a teenager, I had been a yo-yo dieter. I could be around 135 pounds and balloon up to 174. I knew I needed a different way of looking at my life. I couldn't concentrate on those stupid diets where I could lose 20 pounds in a week and then gain it all back over a weekend. But after my mom died at 58 in 1978, I said to myself, "It's not really about my body anymore, it's really about my health." I just became obsessed with health. I read everything I could get my hands on. I starting taking human anatomy classes, going to medical libraries and seeing nutritionists and doctors. And I started experimenting on myself, turning myself into my own guinea pig. It took me about eight years to put together a program. I always say that my health birthday was 1979, but it wasn't until 1987 that I could say I was living a completely healthy lifestyle.

ET: Were you ever really heavy when you were performing in a show? MH: Sure. When I first performed the role of Marty in "Grease" more than 30 years ago I weighed about 175 pounds. But I hid it well. When you wear those 1950s clothes you can get away with it.

ET: When did you start incorporating supplements into your health program? MH: Before I became pregnant with my first son in 1993, I had never been a supplement taker. But I started taking prenatal vitamins and dietary supplements when I was breastfeeding and they made me feel really good. After the pregnancy, I just kept taking them because I was getting the essential nutrients that I couldn't get from food alone. I was getting great stuff from my food, but with all the travel I do-you know, the eating on planes and in restaurants-I couldn't always shop for organic food. I had a doctor who understood the value of dietary supplements and encouraged me to use them. I've taken them ever since and I recommend them to my family and friends, as well as to people through my books and classes.

ET: What supplements other than vitamins do you find helpful in your total nutrition program? MH: I take vitamin E, omega-3 fish oils, antioxidants, garlic, coral calcium and echinacea supplements.

ET: So let's get back to why you decided to testify before Congress in support of supplement use. MH: I know that as soon as you put a celebrity face on an issue, people tend to pay a little more attention. When I was in Washington, I was able to tell Congress the personal stories I've heard about people who turned their lives around-from debilitating illness to vibrant health-when they got the information they need to make good choices. By good choices, I mean rejecting the manufactured foods of our society, with their over-reliance on sugar, meat and dairy, and the chemicals, hormones and steroids that usually accompany these products. Instead, we should be moving towards an organic, vegan diet that produces a sense of physical health. I also believe that a healthy diet includes the use of appropriate dietary supplements.

ET: Do you think that government is moving fast enough to reduce the restrictions on safe supplements? MH: Things could always move faster. But I remember years ago writing letters on behalf of people who wanted supplements without needing a prescription. When I would tell people about the benefits of soy products or supplements, they'd think I was nuts. Now those ideas are mainstream. The floodgates are open and people want to know more. You can't even keep up with all the information. I think that the government knows they're not going to get away with making people have a prescription to take their vitamins.

ET: What is the citizen's responsibility in all this? MH: We're in a real transitional phase and people should take responsibility to educate themselves. You have to question your doctors and recognize when something is or isn't working. You have to find a health practitioner who really knows their stuff.

ET: As you said, there's so much information out there, how do you decipher it all? How can someone be an educated information consumer?

MH: I know it's very difficult because there are so many options. Believe me, I've been doing this a long time and I'm glad I did the research. I think you have to read everything. You have to find a nutritionist/herbalist/doctor who's the real deal and knows what they're talking about. You have to recognize the symptoms in your own body and try to figure it out. I think if you start out with a good multivitamin, a calcium supplement, fish oils and vitamin E, that can be your base and you can't go wrong.

ET: Isn't a diet built on buying organic foods much more expensive? MH: Sure, it's a little more expensive. But there's nothing more expensive than bad health. There's nothing more expensive than food being thrown away because it doesn't taste right. Organic fruit tastes so much better than the perfect-looking fruits and vegetables sprayed with pesticides.

ET: What's your advice to people who want to start a workout and weight-loss program? MH: I'm always saying to people, "Look, you walk your dog, your cat stretches, your hamster runs on a hamster wheel. You're an animal, too, so go move, go do something." I know a lot of people believe that when you want to lose weight you have to go on these 1,200-calorie-per-day diets.

Well, my weight is always between 120-124 pounds and I eat close to 2,000 calories a day, but everything I eat is of quality. And I burn a lot of calories because I wear comfortable shoes and I move around in my life. I'm always strong, I never get sick and I feel like an animal.

ET: How do you view the future of healthcare policy in this country and where do you think nutritional supplements fit in? MH: I strongly believe that the general public needs more access to dietary supplements to maintain essential good health. American research and development has come up with really great products, but the American Medical Association and the drug companies have stigmatized supplements. So what's the result? Most Americans don't have access to safe supplements because they are not covered by their health plans, nor recognized as effective by the federal government. This really needs to be changed.

I think we should take 90% of what we're spending on drugs that barely keep people alive and start spending it on prevention, nutrition and changing lifestyle habits. In this country we're all about curing the disease rather than curing the patient. We don't look at the patient holistically and try to find out how the disease developed. Your doctor should be in charge of keeping you well, not keeping you in that strange state of, what I call, "dis-ease." It's like the medical and pharmaceutical establishment wants to keep you just sick enough so you'll continue to be a paying customer. They've convinced people to think they've got to take a pill to cure themselves rather than use their own bodies.

ET: Do you think medical schools will start training doctors to treat patients holistically and focus more on preventative medicine?

MH: I think we're seeing a lot more nutrition and alternative medicine specialists these days. And the general public is becoming more aware of health and nutrition issues then they were years ago. There's this groundswell of people saying "Wait, I need more information. Wait, my doctor's no longer God. I can't just keep taking these pills and trying to figure out all these warning labels and side effects."

ET: Do you plan on becoming more politically active on these issues? MH: Absolutely, I want to work with any organization that wants to improve school lunch programs, improve the healthcare system and get people more involved in understanding nutrition and disease prevention.

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Vitanet ®

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Date: June 13, 2005 07:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celebrating Women: Age Is Just a Number

Celebrating Women: Age Is Just a Number by Carl Lowe Energy Times, March 10, 2004

As women age, their physical needs shift. The health challenges that face a woman in her thirties do not match those of a woman in her fifties.

At the same time, some basic health needs stay constant: At any age, every woman requires a wealth of vitamins, minerals and the other natural chemicals that fruits, vegetables and supplements supply. She also constantly needs families and friends to support her spiritual health.

As the internal workings of your body alter, your lifestyle must stay abreast of those adjustments. Peak health demands a finely tuned health program designed with your individual needs-and your stage of life-in mind.

Ages 30 to 45

When it comes to maintaining health, younger women might seem to have it easier than older women. If they exercise and stay in shape, they maintain more stamina than women 10 to 20 years their senior.

Unfortunately, many women in this age group mistakenly think they don't have to be as careful about their lifestyle habits and their eating habits as they will in later decades. But even if your health doesn't seem to suffer from poor eating choices or a sedentary lifestyle right away, your foundation for health in later life suffers if you don't care for yourself now.

By age 45 you should have established the good habits that will carry you successfully through the aging process. As an added bonus, good lifestyle habits pay immediate dividends. If you pay attention to your nutrients and get plenty of physical activity when younger, you'll feel more energetic and probably enjoy better emotional health.

Set Health Goals

According to Gayle Reichler, MS, RD, CDN, in her book Active Wellness (Avery/Penguin), good health at any age doesn't just come to you-you have to plan for it. In order to stick to good habits, she says, "living a healthy lifestyle needs to be satisfying." Reichler believes that you need to picture your health goals to achieve them: "Every successful endeavor first begins in the mind as an idea, a thought, a dream, a conviction." Good health at this age and in later years requires a concrete strategy and visualization of how your body can improve with a healthy lifestyle.

Your long-term health goals at this age should include an exercise program that will allow you to reach a physically fit old age with a lowered risk of disability. In addition, your short-term plans should encompass losing weight, staying optimistic, living life with more vim and vigor, increasing your capacity for exercise and lowering your stress.

As Reichler points out, "Your long-term goal and your ideal vision establish what you want to achieve....[You should do] something good...for yourself every day and every week that makes your life easier and more consistent with your goals."

Develop an Eating Plan

Today, the average American gains about two pounds annually. As a result, every year a greater portion of the US population is obese and overweight. By controlling your food intake earlier in life, you may be able to avoid this weight gain. In his book Prolonging Health (Hampton Roads), James Williams, OMD, recommends basic changes to your diet that can provide long-term support of your health:

• Eat foods high in lean protein. Reichler recommends meats like lean beef, poultry, beans and non-fat dairy. • Eat fish. It provides a wealth of healthy fats and protein. "Fish, because it contains the good omega-3 fats, does not need to be lean; the same is true for soy products that do not have added fat," adds Reichler.

Get Supplemental Help

If you're in your thirties or forties and you don't take at least a multivitamin, start taking one today! A large body of research shows that taking vitamin and mineral supplements over a long period of time significantly supports better health.

Calcium and vitamin D are two of the most important supplemental nutrients, helping to build stronger bones now that can withstand the bone-loss effects of aging.

Calcium can also help keep your weight down. One study of younger women found that for every extra 300 milligrams of calcium a day they consumed, they weighed about two pounds less (Experimental Biology 2003 meeting, San Diego).

In the same way, taking vitamin D supplements not only helps strengthen your bones, it can also lower your risk of multiple sclerosis (Neurology 1/13/04). In this study, which looked at the health records of more than 180,000 women for up to 20 years, taking D supplements dropped the chances of multiple sclerosis (although eating vitamin D-rich foods did not have the same benefit). And if you're thinking about having children at this age, a multivitamin is crucial for lowering your baby's risk of birth defects and other health problems. A study at the University of North Carolina at Chapel Hill found that women who take multivitamins during pregnancy lower their children's risk of nervous system cancer by up to 40% (Epidemiology 9/02).

" Our finding, combined with previous work on reducing several birth defects with vitamin supplementation and other childhood cancers, supports the recommendation that mothers' vitamin use before and during pregnancy may benefit their babies' health," says Andrew F. Olshan, MD, professor of epidemiology at the UNC School of Public Health. "We believe physicians and other health care providers should continue to educate women about these benefits and recommend appropriate dietary habits and daily dietary supplements."

In particular, Dr. Olshan feels that folic acid (one of the B vitamins), and vitamins C and A, are particularly important for lowering the risk of childhood cancers and birth defects.

Ages 45 to 55

When you reach this in-between age-the time when most women have moved past childbearing age but haven't usually fully moved into the post-menopausal stage-you enjoy a propitious opportunity to take stock of your health and plan for an even healthier future. One thing that may need adjustment is your sleep habits, as sleeplessness is a common problem for women in this age group. Even if you haven't been exercising or watching your diet until now, it's not too late to start. Making lifestyle changes at this age can still improve your chances for aging successfully.

For instance, it is at these ages that women should have their heart health checked. Research published in the journal Stroke (5/01) shows that having your cholesterol and blood pressure checked at this time more accurately shows your future chances of heart disease than having it checked at a later date after menopause, in your late fifties.

" The premenopausal risk factors may be a stronger predictor of carotid atherosclerosis [artery blockages] because they represent cumulative risk factor exposure during the premenopausal years, whereas the risk factors...during the early postmenopausal years have a shorter time for influence," says Karen A. Matthews, PhD, a professor at the University of Pittsburgh Medical Center. In other words, Dr. Matthews' research shows that if you have high blood pressure and high cholesterol before menopause, you are at serious risk for a stroke or heart attack soon after menopause: These are important reasons that you need to start improving your health habits immediately.

Increase in Heart Disease

Before menopause, a woman's hormones and other physiological characteristics usually hold down her chance of heart disease. After menopause, when hormones and other bodily changes occur, the risk of heart attacks and stroke in women rises significantly. (Heart disease is the leading killer of women.) At least part of this increased risk is linked to the postmenopausal decrease in estrogen production.

Dr. Matthews studied about 370 women in their late forties, measuring their weight, their BMI (body mass index, an indication of body fat compared to height), blood pressure, cholesterol and blood sugar. Ten years later, after the women had entered menopause, she and her fellow scientists used ultrasound to measure blockages in these women's neck arteries (a sign of heart disease).

The researchers found that indications of potential heart problems (such as high blood pressure, high cholesterol and being overweight) when women were in their forties did indeed forecast future difficulties.

" Women who had elevated cholesterol, higher blood pressures and increased body weight before menopause had increased blood vessel thickening and atherosclerotic plaque formation in the neck arteries after menopause. Such changes in the carotid arteries are associated with an increased heart attack and stroke risk," says Dr. Matthews.

Heart Health Factors

The four main lifestyle factors you should adjust at this age to support better heart function are diet, stress, exercise and weight. According to Dr. James Williams, "[M]ore than any other cause, dietary factors are the most critical factor in cardiovascular disease." He recommends eliminating "dietary saturated fatty acids as found in flame-broiled and fried meats." He also urges women to eat more fish and poultry, consume organic fruits and vegetables and cut back on refined sugar.

Stress becomes an ever more important heart disease factor at this age as estrogen begins to drop.

" Our study [in the lab] indicates that stress affects estrogen levels and can lead to the development of heart disease-even before menopause," says Jay Kaplan, PhD, of the Wake Forest University Baptist Medical Center (The Green Journal 3/02).

Dr. Kaplan's research shows that stress in women ages 45 to 55 may reduce estrogen earlier in life and make women more susceptible to the arterial blockages that lead to heart disease. "We know from [lab] studies that stress can lower estrogen levels to the point that health is affected," he says.

Stress can also hurt bone health: In a study of 66 women with normal-length menstrual periods, estrogen levels were low enough in half of the women to cause bone loss, making the women susceptible to osteoporosis.

Exercise and Weight

Although exercise used to be considered to be mainly a young woman's activity, the thrust of recent research suggests that physical activity actually becomes more important to health as you get older.

A 17-year study of about 10,000 Americans found that exercising and keeping your weight down is probably the most important thing you can do to lower your risk of heart disease as you enter your forties and fifties (Am J Prev Med 11/03).

Of the people who took part in this study, more than 1,500 people died of heart disease. Those who performed the most exercise were thinner and had a 50% chance less of dying of heart disease than overweight nonexercisers.

" The fact is that those who both exercised more and ate more nevertheless had low cardiovascular mortality," says Jing Fang, MD, a researcher at the Albert Einstein College of Medicine in the Bronx, New York.

An added benefit of exercise: If you burn up calories exercising, you can eat more and not have to worry as much about being overweight.

Supplements and Diet

If you're a woman at midlife, a multivitamin and mineral is still good nutritional insurance. Eating plenty of fruits and vegetables are also important for getting enough phytochemicals, the health substances in plants that convey a wealth of health benefits.

As you enter this age group, your immune system gradually slows down. To help support immune function, eating produce rich in antioxidant nutrients, and supplementing with antioxidants like vitamins C and E as well as carotenoids, can be especially important. For example, a study of people with ulcers found that people with less vitamin C in their stomachs are more likely to be infected with Helicobacter pylori, the bacteria that can cause peptic ulcers and is linked to stomach cancer (J Amer Coll Nutr 8/1/03).

This research, which looked at the health of about 7,000 people, found that vitamin C probably helps the immune system fend off this bacterial infection.

" Current public health recommendations for Americans are to eat five or more servings of fresh fruits and vegetables a day to help prevent heart disease, cancer and other chronic diseases," says Joel A. Simon, MD, MPH, professor of medicine at the University of California at San Francisco.

Calcium and Bones

At midlife, calcium continues to be a vital mineral for supporting bone health.

According to Gameil T. Fouad, PhD, "It has been routinely shown that a woman's calcium status and level of physical activity (specifically, the degree to which she participates in weight-bearing exercise) are positively associated with bone mineral density. It is less well appreciated that this is a process which takes place over the course of a lifetime."

Dr. Fouad adds that calcium works in concert with other vitamins and minerals to keep bones healthy: "Research in the United Kingdom involving nearly 1,000 premenopausal women over age 40 illustrates those women with the highest bone density tended to have the highest intake of calcium. Surprisingly, this study also demonstrated that calcium does not act alone: those women with the best bone health also had the highest intakes of zinc, magnesium and potassium."

Dr. Fouad stresses that supplements should go together with a lifestyle that includes enough sleep and exercise to help the body stay in top shape.

" As a general guideline," he says, "a woman concerned with her mineral intake should take concrete steps to make sure she is getting adequate rest, is eating a well-balanced diet focused on fresh fruits, vegetables and lean protein as well as getting adequate exercise....A multi-mineral containing bio-available forms of zinc, magnesium, copper and selenium is probably a safe addition to anyone's routine. Taking these proactive steps dramatically reduces the chances that deficiencies will arise."

Ages 55 and Beyond

Entering the post-menopausal phase of life can present challenging opportunities for a new perspective on life and health. While some signs of aging are inevitable, experts who have looked at how the human body changes with age are now convinced that healthy lifestyle habits can improve how well you can think, move and enjoy life well past age 55.

As Dr. Williams notes, "In your fifties, the force of aging is undeniably present: Your body shape changes and organ function declines, both men and women have a tendency to gain weight....Heart disease becomes more common, energy and endurance are considerably reduced and your memory begins to slip."

But Dr. Williams also points out that you don't have to age as rapidly as other people do. He believes you should employ a "natural longevity program...[that starts] to reverse the course of aging as early as possible."

One key to staying vital as you age is your outlook on life, an aspect of life that's greatly enhanced by strong social ties.

Avoiding the Aging Slowdown The latest research shows that one of the most crucial ways to slow the effects of aging is to exercise and keep your weight down. It won't necessarily be easy, though. The change in hormonal balance at this age makes the body more prone to extra pounds (Society for Neuroscience Meeting, 11/12/03).

" In women, it has been demonstrated that major weight increases often occur during menopause, the time in a woman's life in which cyclic ovarian function ends and the ovarian hormones estrogen and progesterone decline," says Judy Cameron, PhD, a scientist in the divisions of reproductive sciences and neuroscience at the Oregon Health & Science University.

In Dr. Cameron's lab trials, she has found that the decrease in estrogen after menopause "resulted in a 67% jump in food intake and a 5% jump in weight in a matter of weeks."

In other words, the hormonal changes you undergo as enter your late fifties causes your appetite to grow as well as your waistline: Developments that increase your chances of heart disease, cancer, diabetes, stroke and joint problems.

Vigilance against this weight gain is necessary to save your health: Start walking and exercising. Research on exercise in people aged 58 to 78 found that getting off the couch for a walk or other physical activity not only helps control weight but also helps sharpen your thinking and helps you become more decisive (Proceedings of the National Academy of Sciences, 2/16-20/04, online edition). This recent study, done at the University of Illinois at Urbana-Champaign, found that performing aerobic exercise improved mental functioning by 11% (on a computer test).

" We continue to find a number of cognitive benefits in the aerobic group," says Arthur F. Kramer, PhD, a professor of psychology at the Beckman Institute for Advanced Science and Technology at Illinois. "The brain circuits that underlie our ability to think-in this case to attend selectively to information in the environment-can change in a way that is conducive to better performance on tasks as a result of fitness." In simple terms, that means that walking at least 45 minutes a day boosts brain power as well as protecting your heart.

An Herb for Menopause

The physical changes that accompan> y menopause can be uncomfortable. But traditional herbal help is available: Black cohosh (Cimicifuga racemosa), an herb used for eons by aging women, has been shown in recent studies to be both safe and effective (Menopause 6/15/03).

" This [research] should reassure health professionals that they can safely recommend black cohosh to their menopausal patients who cannot or choose not to take HRT [hormone replacement therapy]," says researcher Tieraona Low Dog, MD, Clinical Assistant Professor at the University of New Mexico Department of Family and Community Medicine.

While HRT has been used to help women cope with menopause, a flurry of studies in the past few years have shown that HRT increases the risk of heart disease and cancer. Instead, black cohosh, which alleviates such menopausal discomforts as hot flashes, has been shown to be much safer.

Keeping Track of Crucial Vitamins

While continuing to take multivitamins and minerals at this age is important, some experts believe that as we grow older, vitamin D supplementation, as well as taking antioxidant nutrients, is particularly vital. Arthritis is a common affliction of aging, and rheumatoid arthritis (RA) is one particularly destructive form of this joint problem. But taking vitamin D can significantly lower your risk of this condition.

When scientists analyzed the diets of 30,000 middle-aged women in Iowa over 11 years, they found that women who consumed vitamin D supplements were 34% less likely to suffer RA (Arth Rheu 1/03).

Other vitamins are equally important to an older woman's well-being. For example, vitamins C and natural E have been found to lower the risk of stroke in those over the age of 55 (Neurology 11/11/03). In this study, smokers who consumed the most vitamin C and natural vitamin E were 70% were much less likely to suffer strokes than smokers whose diets were missing out on these vitamins.

Rich sources of vitamin C in food include oranges and other citrus fruits, strawberries, red and green peppers, broccoli and brussels sprouts. Sources of vitamin E include vegetable oils such as sunflower seed, cottonseed, safflower, palm and wheat germ oils, margarine and nuts.

Saving Your Sight

After age 55, your eyes are particularly vulnerable. Eight million Americans of this age are at risk for age-related macular degeneration (AMD), a condition that destroys structures in the back of the eye necessary for vision (Arch Ophthal 11/03). But you can drop your risk of AMD by taking supplements of antioxidant vitamins and zinc, according to researchers at Johns Hopkins' Wilmer Eye Institute.

Their research shows that a dietary supplement of vitamins C, natural vitamin E and beta carotene, along with zinc, lowers the chances of progressing to advanced AMD in certain at-risk people by about 25%. Daily supplements also reduced the risk of vision loss by about 19%.

The carotenoids lutein and zeaxanthin also help protect aging eyes. When scientists compared healthy eyes with eyes suffering from AMD, they found that AMD eyes contained lower levels of these vital nutrients (Ophthalmology 2003; 109:1780). Furthermore, they found that levels of these chemicals generally decline as you grow older.

Healthy at All Ages

When it comes to designing a healthy lifestyle, general rules like these can be followed, but you should individualize your plan to fit your needs. No matter which type of exercises you pick out or what healthy foods you choose, look for a strategy and a plan you can stick to. If you think a selection of foods are good for you but you absolutely hate their taste, chances are you won't be able to stick to a diet that includes them.

The same goes for exercise: Pick out activities that you enjoy and that you can perform consistently. That increases your chance of sticking to an exercise program.

Staying healthy is enjoyable and it helps you get more out of life every day, no matter what stage of life you're in.

--
Vitanet ®

Solaray vitamins - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Garlic for the Ages - eat garlic because it's good for your heart...

Date: June 13, 2005 09:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garlic for the Ages - eat garlic because it's good for your heart...

Garlic for the Ages by Phyllis D. Light, RH Energy Times, January 1 , 2004

If you eat garlic because it's good for your heart, you swallow a plant renowned through human history: Garlic was eaten by Roman soldiers for courage; Egyptian slaves ate it to build strength; Christians, Moslems and Hindus include it in their sacred books. Others have used it as an aphrodisiac, a vampire deterrent and a magical charm.

Garlic has a long history as a culinary and medicinal herb that people either love or hate. Its pungent aroma and warming flavor captivates or repels, but its wealth of natural chemicals does great things for your heart.

Garlic (Allium sativum), a member of the onion family, is native to Siberia but, in modern times, has become a treasured naturalized citizen grown all over the world. Garlic's use in folk medicine dates back about 7,000 years, making it one of the oldest known medicinal foods or herbs.

In modern times, garlic is generally used as a condiment lending a unique, pungent flavor to dishes, but in medieval times, garlic was cooked and eaten as a vegetable in its own right. Today you can revel in a wealth of garlic choices, consuming garlic raw, cooked in various recipes, as a dried concentrated powder, as a fresh liquid extract or as aged garlic powder.

Powerhouse Herb

Each little clove of garlic is a powerhouse of good-for-you natural compounds, vitamins and minerals. The biologically active constituents of garlic include allyl sulfur compounds as well as the minerals germanium and selenium.

When you chop up raw garlic and allowed it to stand for about 10 minutes or more, the herb's fragments release an enzyme that converts its compounds from allyl sulfur to another natural chemical called allicin.

Although some allicin is found in garlic before it is cut apart, the yield multiplies considerably when the garlic clove is chopped or pressed and exposed to water (Garlic Conference, Newport Beach, 11/15/98; Penn State).

Many researchers believe that the more allicin produced, the better the health benefits. (Although this is still being debated among the garlic cognoscenti.)

But garlic's benefits don't end meekly on the kitchen counter with its allicin content rising.

Cooked garlic and aged garlic contain other helpful chemicals called diallyl sulphides. Consequently, in any form, garlic produces beneficial health effects.

Fortunately, since raw garlic juice or oil can often irritate the stomach lining, especially in people with sensitive stomachs and delicate digestive systems, garlic supplements and cooked garlic are both helpful for heart health.

Aged Garlic Extract

Aging garlic significantly reduces its irritating compounds and makes it easier on the stomach.

In the aged form, all of garlic's healthy sulfur-containing compounds are converted to water- soluble compounds that retain garlic's natural health benefits. In addition, the pungent odor of the garlic is greatly reduced, an outcome many people desire.

When a group of researchers at Brown University studied the effects of aged garlic extract on people's cholesterol levels, they found that after six months, cholesterol dropped about 6% (Am J Clin Nutr 1996; 64:866-70).

In another study from Brown, researchers found that aged garlic extract reduced platelet adhesion, a sticky blood problem that can cause vessel blockages (New Drug Clin 45(3):456-66). When platelets are less sticky, they are less likely to form blood clots that can cause heart attacks.

Garlic and Heart Disease

A growing body of research shows that a clove of garlic a day can significantly reduce your risk of heart disease.

A four-year study of 280 people who took dried garlic powder three times a day found a striking reduction in the types of arterial plaque blockages that threaten the blood supply to your heart. Interestingly, in this particular study, women displayed a greater reduction in plaque than men (Atherosclerosis 2000; 150:437-8).

Another study found that garlic may also keep important blood vessels more supple and less likely to spasm. Arterial spasms have been linked to heart attacks and other cardiovascular problems in women.

Aortic Complications

As you age, the aorta, one of the main arteries that carries blood, may harden, reducing blood flow from the heart and placing damaging stress on a number of other bodily organs. In research at Ohio State University, people who took garlic supplements had 15% less aortic stiffness than people who avoided garlic (Circulation).

In this study, scientists found that the older people enjoyed the greatest cardiovascular benefits from daily garlic use.

Researchers believe this extra benefit is linked to the fact that as you age, the endothelial tissue in the linings of the aorta and other blood vessels become less responsive to the need to dilate (expand). As a result, when more blood flow is required, and the heart pumps faster, these vessels take more of a beating from the friction of blood passing through them.

That restriction in dilation has two damaging consequences: In one instance, vessel walls can be injured. In response to these injuries, cholesterol collects on artery walls, plaque forms and the blood supply to the heart muscle can be restricted, leading to a heart attack. In other cases, arteries can restrict blood flow to the heart simply because of the inability to expand sufficiently.

The Ohio State researchers found that arteries in folks aged 70 to 80 benefited the most from taking garlic. But those in their 60s also benefited significantly.

Garlic's natural antioxidant properties can also help protect the heart from damage after surgery (BMC Pharmacology 9/02).

In a study performed on lab animals, researchers found that oxidative stress, a source of cell damage that takes place after surgery, dropped when the animals ate a diet that included garlic.

Oxidative stress can seriously reduce cardiac function, limit the amount of blood the heart can pump and cause permanent damage to the heart muscle.

Garlic Against Blood Clots

Under normal circumstances, blood clots serve a useful purpose: Cut yourself and a blood clot stops the bleeding. Without this clotting ability, you might bleed to death. But if your blood is too prone to clotting, these clumps can cut off blood supply to your heart and other organs, endangering your life.

In a study of apparently healthy individuals whose relatives had already suffered from heart disease, researchers found that their blood formed thick, tangled blood clots, increasing their risk of heart problems (Circulation rapid access 9/23/02). These blood clots are made of a substance called fibrin, a protein in the plasma that can form elastic threads that cut off blood flow.

While these researchers recommended aspirin as an anti-clotting measure for people at risk of heart disease, garlic can also help break up fibrin and possibly lower your chance of heart problems (Pharmatherapy 5(2): 83).

The fibrin that forms clots is produced by blood cells called platelets. Other scientists who have looked into garlic's benefits believe that one of its natural chemicals called ajoene may keep platelets from producing excessive fibrin and gumming up the flow of blood through arteries.

If you've rarely indulged in garlic, you may need a period of adjustment in growing accustomed to its unique taste and aroma. But its heart benefits confirm the long-ago observation by Pliny, an ancient Roman naturalist, that "garlic has powerful properties."

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Nutrients for Longevity

Date: June 10, 2005 09:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nutrients for Longevity

Nutrients for Longevity by Edward C. Wallace, ND, DC Energy Times, September 1, 1999

What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful easy feeling.

How Do We Age

Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.

The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.

Programmed Cell Theory

In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.

Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.

Free Radical/Oxidative Stress Theory

The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain.

On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution.

Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.

DNA Repair Theory

Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.

What Can We Do

The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.

In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."

Antioxidant Protection

Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.

Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.)

Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.

In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725).

Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.

Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.

Nutrition Deficiencies

A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).

When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).

A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.

Longevity Diets

A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460)

Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers. (Epidemiology 3[5], 1992: 389-391).

Staying Alive

Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.

Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects. (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).

In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.

Longevity and Exercise:

Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.

Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184).

In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.

The Treadmill of Life

The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying. (JAMA 273 [14], April 12, 1995: 1093-1098).

Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.

Longevity Supplementation

Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging.

Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.

Toning Down Enzymes

Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls.

In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).

In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.

The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).

Vitamins E & C

A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.

Chronological Age Vs. Biological Age

Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.

Similar Relationship

A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.

The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).

Carotenoids

When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.

Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119(1), Jan. 1989: 112-115).

Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.

Flavonoids

Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs.

For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.

Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).

Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.

Amino Acid Health

Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68).

As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.

Attitude & Behavior

Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit.

In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).

In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).

Longevity at Last

While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of living longer. An added benefit: By staying healthier, your old age won't only be longer, it will be more enjoyable, too.

And, who knows, if you hang around long enough, taking your nutrients and getting a comfortable amount of consistent exercise, while meditating and refusing to succumb to stress, that magic bullet that will keep you alive for centuries may be discovered. Some day a new antioxidant or other substance may finally prove to provide the elusive fountain of youth. Stay tuned.

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Vitanet ®

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Resveratrol - New Hope for Long Life ...

Date: June 06, 2005 08:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Resveratrol - New Hope for Long Life ...

Resveratrol

We all want to live long, vibrant and healthy lives. At one time intervention in the aging process was regarded as mere fantasy—but today it is within our reach due to breakthroughs in nutritional science. Resveratrol, a compound that is abundant in red wine, has been making headlines recently for its anti-aging potential and its well-documented antioxidant and cardiovascular benefits. Resveratrol has been shown in new research at Harvard Medical School to increase the lifespan of yeast cells—a finding that may help explain the lifeextending effects of the Mediterranean diet. Now Source Naturals offers you RESVERATROL from a non-alcoholic source. RESVERATROL is part of Source Naturals’ extensive line of scientifically based nutrients, designed to help you shape a successful anti-aging program.

Resveratrol in the News

Researchers at Harvard Medical School recently made headlines when they identified a plant molecule they believe may hold the key to slowing the human aging process. The compound, resveratrol, is produced by grapevines and other plants in response to environmental stress. The groundbreaking study, reported in the journal Nature, showed that resveratrol mimics the life-extending effects of calorie restriction and increases the lifespan of yeast cells by up to 80%. Resveratrol was found to activate certain enzymes that influence the genes that regulate aging. This research may help explain the long-established association between moderate red wine consumption and cardiovascular health and longevity.

Wide-Ranging Anti-Aging Benefits

Previous research has documented resveratrol’s many health benefits:

• Resveratrol was found to inhibit the Cox-1 and Cox-2 enzymes, which are involved with cellular irritation and cellular growth and regeneration, according to in vitro studies. Recent research focuses on its role in suppressing Cox-2 via the action of NFkappa B, an important DNA regulating factor.

A Non-Alcoholic Source

Most publicity about resveratrol focuses on its presence in grape skins and red wine. However, this beneficial compound is found in other plants. Source Naturals RESVERATROL is a standardized extract of Hu Zhang root, a celebrated traditional Chinese herb. This offers consumers the advantage of a non-alcoholic source. Each tablet contains 500 mg of Hu Zhang extract, yielding 40 mg of resveratrol activity. RESVERATROL is available in bottles of 30 or 60 tablets.

Nature’s Protectant

Source Naturals, the science company, is pleased to partner with your natural foods retailer in bringing you this botanical treasure. For a long and vital life, RESVERATROL belongs at the center of your anti-aging regimen.

References:
Bowers, J.L. et al. 2000. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. Endocrinol. 141(10):3657-67. Fustier, P. et al. 2003. Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines. Brit J Cancer. 89(1):168-72. Howitz, Konrad T. et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. (Published online 8/24/03 in advance of print publication) Jang, M. et al. 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 275(5297):218-20. Pace-Asciak C.R. et al. 1996. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta. 246(1-2):163-82.

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VitaNet ® Staff

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Improve Your Diet and Stop Being S.A.D.

Date: May 27, 2005 09:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Improve Your Diet and Stop Being S.A.D.

Improve Your Diet and Stop Being S.A.D.

The Standard American Diet (or S.A.D.) is exactly that ? sad! Sadly lacking in essential nutrients and sadly loaded with an excess of the wrong things, like fat, cholesterol, salt and sugar. How can we improve our diets and truly nourish our bodies?

Eat More Fruits and Vegetables

Why are fruits and vegetables so important? Not only are they high in vitamins and minerals, but they also contain bioflavonoids?naturally occurring plant constituents that act as antioxidants and support the integrity of our connective tissue. And fruits and vegetables are high in fiber, so crucial in maintaining our digestive tract health.

What fruits and vegetables don't contain is just as important as what they do contain: fruits and vegetables are free of cholesterol, additives and preservatives, contain no added sugar or salt, and are low in fat?nature's perfect foods. All you have to do is look at the bright, crisp colors?the vibrant greens, yellows, oranges, reds and purples?to know how good fruits and vegetables are for you.

Eat More Whole Grains

Whole grains, like oats, brown rice and barley, help us meet important nutritional goals. They are low in fat and high in fiber, and, because the germ of the grain has not been lost in the milling process, they are higher in essential fatty acids, vitamin E and B vitamins compared to processed grain products like white bread or pasta. And they're delicious! Have a bowl of hot oatmeal with fresh fruit and nuts for breakfast?or make a hearty barley-vegetable stew for dinner. Your body will thank you!

Increase Your Fiber Consumption

Fiber exercises our digestive tract?toning and strengthening the muscle that surrounds our intestines just the way lifting weights tightens and tones our skeletal muscles. Low-fiber diets increase our risk for a variety of bowel problems, from constipation and hemorrhoids to diverticulosis and diverticulitis to colon cancer. Increasing fiber in the diet is good for the digestive tract, helps regulate blood sugar and may also help reduce cholesterol levels.

What are the best dietary sources of fiber? All plant foods (whole grains, legumes, fruits, vegetables, nuts and seeds) contain fiber. And all animal products (meat, poultry, fish, eggs and dairy products) contain zero fiber?that's right, none!

Eat Healthy Fats and Oils

Fats and oils have gotten a bad rap. Somehow the idea has been promoted that all fats are bad and we should eat as little fat as possible. The truth is that fat is an essential part of our diet, and dietary fats are used for many important functions in the body, from energy production to cell membrane maintenance to nerve conduction. While much of the focus has been on the amount of fat we should eat, the type of fats we eat is at least as important.

High-quality fats are rare in the standard American diet. Most of the fats and oils we eat have been damaged by exposure to heat or light during processing or cooking. This damage destroys essential nutrients and creates free radicals, chemically unstable molecules that can wreak havoc in the body. For this reason, fried foods and highly processed fats like margarine and shortening are best avoided. Health concerns have been raised about margarine, as it contains trans fatty acids?a configuration of fatty acids not found in nature.

And our ratio of fat consumption is skewed. Most Americans consume too many saturated fats and not enough polyunsaturated oils. How do you tell which fats are saturated and which are not? Saturated fats are solid at room temperature (think butter, lard and coconut oil). Polyunsaturated oils are liquid at room temperature (like corn oil, safflower oil and sunflower oil). In addition to polyunsaturated oils, olive oil, a monounsaturated oil, is also a heart-healthy choice and one of the best oils to use.

Reduce Your Consumption of Animal Products

While animal products (meat, poultry, fish, eggs and dairy products) contain many valuable nutrients, as a nation, we tend to overdo it. A diet high in animal products is a diet high in cholesterol, and is strongly linked to the number-one killer in the industrialized nations: cardiovascular disease, which includes high blood pressure, heart attacks and strokes.

How do you know which foods contain a lot of cholesterol without having to read labels? All animal products contain cholesterol. All plant foods (grains, legumes, fruits, vegetables and nuts and seeds) contain zero cholesterol. It's that simple. Eating a predominantly vegetarian diet is one way to maintain your cardiovascular health.

Avoid Stimulants?Like Caffeine

Most people think caffeine "gives" them energy. Nothing could be farther from the truth! Caffeine in fact robs the body of energy?by withdrawing from your energy 'savings account' now, leaving you less reserves to draw upon later. The pick-me-up feeling artificial stimulants provide is inevitably followed by an energy crash.

Reduce Your Caloric Intake

About a quarter of the U.S. population is now considered to be obese, and the numbers are rising. Our children are increasingly overweight, from a steady diet of junk food and TV-watching. As a nation, we are overfed and undernourished?our diets are too high in "empty" calories and too low in essential nutrients.

Being overweight significantly increases the risk for a variety of cancers, including colon, prostate, breast, ovarian, and uterine cancer. Animal studies have shown that the only consistent way to extend the life spans of laboratory animals is to put them on a lower calorie diet. Thinner rats live longer?and we suspect the same is true for humans.

Lighten Up!

Are you too serious about your diet? Do you miss out on social opportunities because you are too busy counting calories or grams of fat? Lighten up! To paraphrase one poet, "?Tis better to eat steak and beer with cheer than sprouts and bread with dread!" Don't allow your dietary restrictions to rule you or limit your social life.

Eating out is possible, even on a restricted diet. Most restaurants are willing to accommodate your requests. It's just a matter of learning how to order the healthiest meal possible. Good options include poached fish with lemon, salads with vinaigrette dressing, and plain baked potatoes. Get in the habit of ordering sauces on the side and avoid filling up on empty calories, like white bread rolls.

Take Time To Savor Each Meal

We often make the mistake of eating hurriedly, standing at the sink wolfing something?anything!?down so we can move on to the next activity in our busy lives. But digestion actually functions better when we take the time to slow down. The parasympathetic nervous system is responsible for enhancing circulation to the digestive organs and promoting the flow of digestive juices. There is only one catch?we must be relaxed for our parasympathetic nervous system to predominate. So, take a deep breath and relax, there's plenty of time!

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VitaNet®
VitaNet ® Staff

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Garlic for Treating Hypercholesterolemia - A Meta-Analysis ...

Date: May 12, 2005 12:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garlic for Treating Hypercholesterolemia - A Meta-Analysis ...

Garlic for Treating Hypercholesterolemia - A Meta-Analysis of Randomized Clinical Trials

Author:
Stevinson C, Pittler MH, Ernst E

Source:
Ann Intern Med. 2000;133:420-429.

Abstract:
PURPOSE: To investigate the effect of garlic on total cholesterol level in persons with elevated levels by conducting a meta-analysis of randomized, double-blind, placebo-controlled trials.

DATA SOURCES: Systematic literature searches were conducted on the MEDLINE, EMBASE, BIOSIS, Cochrane Library, AMED, and CISCOM databases. Manufacturers of commercial garlic preparations and experts in the field were asked about published or unpublished trials.

STUDY SELECTION: Selected trials were required to state that they were randomized, double-blind, and placebo-controlled; use garlic monopreparations; include persons with mean total cholesterol levels of at least 5.17 mmol/L (200 mg/dL); and report total cholesterol level as an end point. There were no language restrictions.

DATA EXTRACTION: Two reviewers, blinded to key identifiers of each paper, independently extracted data in a standardized manner and assessed methodologic quality by using the Jadad scale. Discrepancies were settled through discussion.

DATA SYNTHESIS: In the 13 trials included in the meta-analysis, garlic reduced total cholesterol level from baseline significantly more than placebo (P < 0.01); the weighted mean difference was -0.41 mmol/L (95% CI, -0.66 to -0.15 mmol/L) (-15.7 mg/dL [CI, -25.6 to -5.7 mg/dL]). Six diet-controlled trials with the highest scores for methodologic quality revealed a nonsignificant difference between garlic and placebo groups; the weighted mean difference was -0.11 mmol/L (CI, -0.30 to 0.08 mmol/L) (-4.3 mg/dL [CI, -11.7 to 3.1 mg/dL]).

CONCLUSIONS: The available data suggest that garlic is superior to placebo in reducing total cholesterol levels. However, the size of the effect is modest and the robustness of the effect is debatable. The use of garlic for hypercholesterolemia is therefore of questionable value.
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Date: May 09, 2005 06:10 PM
Author: Darrell Miller (dm@vitanetonline.com)

It's in the Blood

Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

“The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

“Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

"Blur of Products"

With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

“The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

“Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

“The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

“In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

New Weapons

There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

“Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

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