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An Overview of Garcinia Cambogia and its Benefits   
Date:
October 18, 2022 03:07 PM
Garcinia cambogia is a plant native to SE Asia that has been used for centuries by traditional herbalists. Garcinia's primary bioactive constituent, Hydroxycitric Acid (HCA), has been extensively studied for its effects on citrate lyase, which is the main enzyme responsible for the cellular synthesis of fatty acids. Scientific studies indicate that in the presence of HCA, cells produce fewer fatty acids from carbohydrates. The active ingredient in Garcinia Cambogia is Hydroxycitric Acid (HCA), which is extracted from the fruit’s rind. Hydroxycitric Acid is a natural substance that has demonstrated impressive weight loss results in scientific studies. How Garcinia Cambogia Can Help You Lose Weight Hydroxycitric Acid works by inhibiting the enzyme Citrate Lyase, which is responsible for converting unused carbohydrates into fat storage. By blocking this enzyme, HCA prevents unused carbohydrates from being stored as body fat and instead allows them to be used for energy production, which can lead to weight loss. In addition, Hydroxycitric Acid also acts as an appetite suppressant by increasing levels of serotonin, a brain chemical that promotes feelings of satiety and well-being. The Benefits of Garcinia Cambogia There are many benefits associated with taking Garcinia Cambogia extract, including weight loss, decreased appetite, and increased energy levels. However, perhaps the most impressive benefit of Garcinia Cambogia is its ability to help people lose weight without making any changes to their diet or lifestyle. This makes Garcinia Cambogia an ideal supplement for people who are looking to lose weight but don’t have the time or inclination to make major changes to their habits. If you’re looking for a natural way to lose weight without making any changes to your diet or lifestyle, then Garcinia Cambogia may be right for you. This supplement has been shown to block the enzyme Citrate Lyase, which is responsible for converting unused carbohydrates into fat storage. In addition, Hydroxycitric Acid also acts as an appetite suppressant by increasing levels of serotonin, a brain chemical that promotes feelings of satiety and well-being. So if you’re looking for an easy way to lose weight without diet or exercise, then give Garcinia Cambogia a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6507) The Benefits of NOW Clinical Cardio 
Date:
September 30, 2022 12:37 PM
If you're looking for a comprehensive way to support optimal cardiovascular health, look no further than NOW Clinical Cardio. This powerful combination of targeted nutrients and botanicals helps promote healthy cardiovascular structures and functions.* With L-carnitine and CoQ10 to support energy production in the heart, hawthorn and MegaNatural®-BP™ grape seed extract to support blood pressure already within the normal range, and MK-7 to help maintain arterial flexibility, Clinical Cardio offers a broad range of benefits for those looking to maintain a healthy heart.* How NOW Clinical Cardio Works NOW Clinical Cardio is a powerful formula that contains a combination of targeted nutrients and botanicals that are known to support optimal cardiovascular health.* The nutrients and botanicals in Clinical Cardio work synergistically to provide a comprehensive approach to maintaining a healthy heart.* L-carnitine is an amino acid that is synthesized in the liver from methionine and lysine. L-carnitine plays an important role in energy production by transporting fatty acids into the mitochondria where they can be used for fuel.* In addition, L-carnitine has been shown to support healthy heart function and protect against oxidative stress.* CoQ10 is another important nutrient for energy production, as it is involved in the electron transport chain in mitochondria.* CoQ10 levels have been shown to decline with age, so supplementation may be especially important for older adults.* Like L-carnitine, CoQ10 has also been shown to support healthy heart function while protecting against oxidative stress.* Hawthorn is an herb that has been used traditionally for centuries to support cardiovascular health. Hawthorn's primary mechanism of action is vasodilation—the widening of blood vessels—which supports healthy blood pressure already within the normal range.* Additionally, hawthorn has antioxidant activity and can help protect the heart from free radical damage.* MegaNatural®-BP™ grape seed extract is a patented extract of whole red grapes that has been shown in clinical studies to help maintain already healthy blood pressure levels.* MegaNatural®-BP™ contains polyphenols—powerful plant compounds with antioxidant activity—which may help explain its beneficial effects on blood pressure levels.* MK-7 is a form of vitamin K2 that is derived from natto, a traditional Japanese fermented food. Vitamin K2 is involved in calcium metabolism and has been shown to promote arterial flexibility by keeping calcium Hydroxyapatite out of soft tissues such as arteries.* By promoting arterial flexibility, MK-7 helps maintain healthy blood flow throughout the body.* Conclusion: NOW Clinical Cardio is a comprehensive formula that contains nutrients and botanicals that are known to support optimal cardiovascular health. With L-carnitine and CoQ10 for energy production, hawthorn for blood pressure support, MegaNatural®-BP™ grape seed extract for antioxidant protection, and MK-7 for arterial flexibility, Clinical Cardio offers a broad range of benefits for those looking to maintain a healthy heart. Try it today!* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6476) The Benefits of NOW Calcium Hydroxyapatite
Date:
September 23, 2022 03:57 PM
For those looking for a natural and highly absorbable source of calcium, NOW Calcium Hydroxyapatite is an excellent option. This supplement is derived from Australian, certified BSE-free, young pasture-fed cattle and includes calcium, phosphorus, magnesium, protein, minerals and amino acids. These nutrients are essential for healthy bone formation and upkeep.* Below we'll dive into some of the specific benefits of NOW Calcium Hydroxyapatite. Some of the primary benefits of NOW Calcium Hydroxyapatite include:
Calcium is essential for strong bones and teeth. It also supports muscle contraction, nerve function and cardiovascular health. Phosphorus works with calcium to build bones and teeth and helps the body use carbohydrates and fats. Magnesium plays a role in over 300 biochemical reactions in the body including energy production, muscle contraction, nerve function and blood sugar regulation. Protein provides the building blocks for bones, muscles, cartilage, skin and blood. Minerals such as zinc, copper and manganese are involved in bone formation.* Amino acids such as lysine and methionine are needed for the proper absorption of calcium.* In Summary: NOW Calcium Hydroxyapatite is an excellent supplement for those looking for a natural source of calcium that is easily absorbed by the body. In addition to calcium, this supplement also includes phosphorus, magnesium, protein, minerals and amino acids which are all essential for healthy bones.* If you're interested in supporting healthy bones*, NOW Calcium Hydroxyapatite is a great option.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6459) Reverse liver damage with this food
Date:
April 21, 2017 06:44 AM
Researchers at the University if Chile that wanted to study how olive oil works to keep the heart healthy also found that it benefits liver health. The compound hydroxytyrosol, found in olive oil, can reverse liver damage caused by a high fat diet. Olive oil can be used for cooking and baking but can also be eaten as salad dressing, or even a dip for bread. It's easy to get creative while keeping both your heart and liver healthy. Read more: Reverse liver damage with this food
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4447) How does CBD help with Seizures
Date:
December 19, 2016 10:28 PM
Seizures are the sudden changes in the brain's electrical activity. It usually affects how a person acts for a short period of time or appear. The symptoms of seizure include a loss of control and violent shaking. There can be several causes for the seizures. Anything that affects the brain's normal activity can lead to seizures. Several causes of seizures include injury to the head, fever, disease or even certain uses of medications. A person suffering from regular seizures due to brain disorder is called to be having epilepsy. Seizures can take different forms that affect many people in different ways, as some people call it electrical storms in the brain. CBD has several therapeutic effects. Unlike THC, CBD has a less binding affinity to the CB1 and CB2, those are Cannabinoid receptors. Instead, CBD stimulates endogenous cannabinoid signal by suppressing enzyme fatty acid amide Hydroxylase (FAAH). CBD helps in enhancing endocannabinoid by suppressing FAAH. CBD also opposes the action of THC at CB1 receptor, thus help to mute the effects of THC. CBD also stimulates 2-AG, that activates the CB1 and CB2 receptors, where CB2 receptors are predominant in the immune system and peripheral nervous system. It is found that CBD binds directly with 'G-protein' coupled receptors and other ion channels to grant therapeutic effect. CBD is also known as the TRPV-1 stimulant that helps, CBD-rich Cannabis in the effective treatment of the neuropathic pain.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3674) Does Garcinia Help With Weight Loss?
Date:
August 17, 2015 05:40 PM
Garcinia cambogia, a tropical fruit obtained from a herb called Malabar tamarind, has for a long time been used as a weight loss supplement. Garcinia cambogia is found to grow naturally in South East Asia and some parts of Indonesia. Traditionally, this herb was used as food flavor by traditional communities in India. The fact that this supplement is obtained naturally implies that it has minimal side effects when used for weight loss by an individual. How does Garcinia cambogia works? The critical component that gives Garcinia cambogia its weight loss property is called Hydroxycitric acid or simply HCA. Garcinia cambogia works through;
What determines the success of Garcinia cambogia in any weight loss program is the concentration of HCA. The recommended HCA concentration that you should buy is 60%. Moreover, it is also imperative to consider shopping for the Garcinia cambogia products that are certified and approved by the Food and Drug Administration. This is to ensure that what you are shopping is safe and suitable for all your individual weight loss needs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3196) BENEFITS OF TURMERIC
Date:
July 21, 2015 03:38 AM
Turmeric or also known as "the golden spice of life", is an important culinary ingredient around the world. Turmeric is a tropical perennial herb that is domestically cultivated in India since the ancient times. It has been used for thousands of years as the main ingredient for curry. It gave the golden color to Indian food and dishes. Additionally, other than being used as a curry in most Indian cooking, turmeric is also known for its medicinal value. It was used by ancient Indians to treat a multitude of conditions.
Adding turmeric in your everyday diet, effortlessly turns your kitchen and dish into a good resource of health and healing. Turmeric has gained popularity in the recent days for its potential in lowering cholesterol, reducing blood sugar in diabetics, reducing colon inflammation, healing wounds, and fighting cancer as well as preventing Alzheimer’s disease. It is known to contain anti-inflammatory antiseptic and antioxidant qualities. Without much explanation, it means continuous use of turmeric in our dishes improves our chances to be protected from major illnesses. "Turmeric" is made from turmeric roots that are dried and powdered making it easy to put in food as curry. This root powder contains the healing compound, curcumin. Other parts of the plant also have healing abilities. Here are other benefits of turmeric:
Turmeric is not only used as a culinary ingredient but also as a good resource of healing. This article covers only a few of the benefits of using turmeric, there are more uses and a number of researches to discover the wonders of "the golden spice of life." //www.hungryforchange.tv/article/6-ways-the-golden-spice-of-life-can-heal-your-body
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3172) L-Leucine as an essential Amino Acid
Date:
May 31, 2014 06:54 AM
L-Leucine is a a-amino acid with the chemical formulae HO2CCH(NH2)CH2CH(CH3)2. It is a hydrophopic amino acid to its aliphatic isobutyl side chain. L-Leucine is an essential amino acid since the human body can’t synthesize it, and it therefore must be ingested. What is an essential amino acid These are the amino acids that can’t be synthesized by the body of the organism hence it must be supplied in the diet. These amino acids is important not because they are important than others, but simply because the body can’t synthesize them. Phenylalanine, L- Leucine, Valine, Tryptophan, Threonine, meyhionine, iso - Leucine, lysine and histidine are some of amino acids regarded as essential for humans beings. The main difference between essential and non-essential amino acids is somehow since some proteins can be synthesized from others. The sulfur containing amino acids such as L-Leucine may sometimes be referred to as an essential amino acid. Effects of L-Leucine deficiency Majority of amino acids are important in the human diet. An experiment carried out by William Cummings Rose showed that lack of L-Leucine results to symptoms of exhaustion, nervousness and dizziness. Results further showed that these symptoms were encountered to lesser extent whenever human subjects were deprived of an essential amino acid. In plants and other micro-organisms, L-Leucine is synthesized from pruvic acid by several enzymes. These enzymes include: · a-Isopropylmalate synthase · L-Leucineaminotransferase · a-Isopropylmalate isomerase · Acetolactate synthase · AcetoHydroxy acid isomeroreductase · DiHydroxyacid dehydratase Importance of L- Leucine L-Leucine is used by the adipose tissue, liver and the muscle. In muscle tissue and adipose L-Leucine is used in the formation of sterols. Ironically the combined usage of L-Leucine in the muscle and adipose is seven times greater than its use in the liver. L-Leucine is also used in stimulation of the muscle protein synthesis. In dietary , L-Leucine is used in to slow down the degradation of muscle tissue by increasing the synthesis of muscle proteins in aged rats however this does not work in elderly men. L-Leucine helps you lose weight and spare muscle when dieting. However L-Leucine can’t be associated as the main reason in muscular growth for the entire populatin. L-Leucine activates the mammalian target that regulates the growth cells in rats. Negative effects of L- Leucine L-Leucine cause neurologic complications which may be fatal if not control in time. Studies also show that over activity of the liver is caused by taking L-Leucine supplement, excess L-Leucine may also cause pellagra, whose symptoms include dermatitis, diarrhea, dementia and eventually death.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3130) Can 5-HTP Help with Sleep?
Date:
May 26, 2014 12:57 PM
What is 5-HTP 5-HTP (5-Hydroxytryptophan) is a compound which is produced naturally in the body via the means of the amino acid tryptophan. Even though this compound is already present in the body, researchers have found that we can benefit by having more of it. This has resulted in several supplement companies producing this compound from the seeds of an African plant known as Griffonia simplicifolia; 5-HTP can now be found in many health food and drug stores. Benefits of 5-HTP Even though there still hasn't been much research done regarding this supplement, we can still see that there are many uses for it. However, there is sufficient evidence out that shows 5-HTP is effective in treating depression and fibromyalgia, which means improved mood, reduced pain, better joint health, and better quality of sleep. To elaborate on the sleep benefits, 5-HTP increases serotonin levels which are converted into melatonin (a hormone which helps keep sleep cycles under control) through the body. There is also some evidence to suggest that this supplement can reduce anxiety as well as help promote weight loss in obese people. So there is some great evidence to suggest that this supplement can help to improve our mood, quality of sleep, health and much more. However there is a slight downside, because of the limited amount of research done on this compound it is currently considered possibly unsafe to use. Potential side effects of 5-HTP include muscle ache/pain, heartburn, nausea, vomiting, drowsiness, stomach pain, and also a serious condition known as eosinophilia myalgia syndrome – a rare flu-like condition. Drug interactions can take place also; you should stay away from 5-HTP especially if you are taking any anti-depressant medication as these often increase serotonin levels which may result in too much serotonin in the body. In conclusion This supplement has many benefits and there has been research done to prove that it is effective in treating many problems such as insomnia, depression, fibromyalgia, anxiety, weight loss and more. However, it is recommended that you stay away from supplementing with 5-HTP because of the limited research done.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3125) Can Glutamine Improve Nitrogen Balance in the Body?
Date:
May 07, 2014 09:08 AM
Can Glutamine Improve Nitrogen Balance in the Body? Essentials of glutamine have been found to be many. Nowadays there are commercially produced glutamine which are taken as strong anti-catabolic supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3113) Citrimax
Date:
December 20, 2013 09:14 AM
Citrimax is a global popular weight loss supplement drug which is believed to help in to burning of fats which are excess in the body since this fats are stored in the fat reserves. It is one of the plant extracts from the South Asian fruit known as the Garcina cambogia which contains naturally occurring deposits of Hydroxyl citric acid. This has been proved to be the source of appetite suppressant which results to the blockage of deposits of the fats enhancing metabolism. Benefits of Citrimax The tablets are believed to have been formulated and proven to be effective and preferably safe in clinical tests which have been conducted so far. Results have shown that these tablets can greatly suppress the appetite and to a greater percentage inhibits the production of fat in the body without any adverse effects on the dieter’s nervous system. The Citrimax are different from the rest of the body weight products because of the presence of the Hydroxyl citric acid which normally fails to stimulate the central nervous system. Though there have cases associated with the nervous anxiety, Citrimax still remains to be a product with no risk at all since it does not cause drastic side effects. These tablets work by hindering the enzymes which breakdown carbohydrates into the stored fat in the body. It also promotes an increase in stored energy as to be in form of glycogen. It normally provides away of melting excess fats in the body. The Citrimax tablets Give an important impression in their usage since they work by altering the enzymes converting carbohydrates into fats since the carbohydrates stored as fats are used for energy and the body to store the same energy in form of glycogen which then is a channel of communication for the brain information which leads to turn off of hunger signals. .
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2932) 5-HTP and how it can help promote natural sleep patterns.
Date:
November 27, 2013 07:47 AM
What is 5-Hydroxytryptophan (5-HTP)?
Serotonin deficiency The production of serotonin declines with age, however it’s also important to note that, at any age serotonin production can be further compromised by stress. Low serotonin levels are commonly manifested by insomnia, depressed mood and anxiety. Good sleep. It is known that insomnia is an age-related condition. Sleep disorders are associated with very significant psychological, medical and social disturbances. Sleep deprivation can cause depression, stress and anxiety, it can also lead to fatigue, impairment of memory, immune function and mood. Nutritional supplements that contain 5-HTP, choline, melatonin and valerian root helps one to get a good sleep hence alleviating these problems. Recent research has indicated that increased serotonin levels can assist individuals suffering from chronic sleep disturbances restore healthy sleep patterns. Pathways of serotonin One of the metabolic pathways of serotonin leads to melatonin a hormone widely acknowledged for being responsible for the sleep-wake cycle. By increasing serotonin’s level with 5-HTP, you are also increasing the melatonin levels. Melatonin is also known to improve the immune function and assist improve immunodepressions that are stress-induced. Valerian root Valerian root is a Eurasian herb that has been for long known for enhancing sleep. Valerian helps one to fall asleep and also improves the quality of sleep thus allowing one to wake up feeling refreshed. A study showed that people who used valerian were more active and alert . Choline Choline is a nutrient precursor to neurotransmitter acetylcholine, that assists to protect your sound sleep so that you are not woken up by every little murmur or cleak.Supplementing the diet with these natural substances will assist eradicate or diminish sleep disturbances and also assist reestablish healthy sleep patterns. Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2906) Facts about Astaxanthin
Date:
October 22, 2013 10:47 PM
Astaxanthin is said to be a carotenoid which belongs to larger class of phytochemicals which is known as terpenes. It is built up of five carbon precursors. It is a metabolite of canthaxanthin and zeazanthin which contains both ketone and Hydroxyl fuctional groups. Astaxanthin is a lipid-soluble pigment and is colorful. The color of it is due to the extended chain of conjugated double bonds which is also responsible for the astaxanthin’s antioxidant function. It is found in feathers of some birds, yeast, trout, shrimp, crustaceans, crayfish, krill, salmon and micro algae. The red color of cooked shellfish and red color of salmon is due to the presence of astaxanthin.
How Astaxanthin Helps the Eyes?
When astaxanthin is combined with omega-3 fatty acids and Vitamin E then it helps the eyes to recover the watery condition and it lubricates it too. It helps the eyes to absorb Vitamin E by which it then nurtures and feeds the choroid and optical nerve which is behind the retina. This is the place where the blood vessel enters in to and leaves and this is the place where communication between retina and brain are established. The macula is protected by astaxanthin by its antioxidant activity and it also helps in eliminating the free radicals. It helps in reducing the risk of cataracts and AMD. It also helps in preventing the eyestrain and it also decreases its effects. The inflammation in the muscles of the eyes is decreased by it and it also improves the blood flow of the eyes.
Health Benefits of Astaxanthin
It is considered as a strongest natural antioxidant which crosses the brain-blood barrier and protects the nervous system and brain, works in every part of skin, organs and body, crosses the retinal-blood barrier and thus protect the eyes and it reaches inside and out of every part of the cell. It also helps in repairing the injured tissue. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2852) What Are The Health Benefits Of Acai?
Date:
October 16, 2013 10:12 AM
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2851) What Are The Health Benefits Of A Mushroom Formula?
Date:
December 29, 2012 11:39 AM
Three Important Mushrooms And Their Benefits: You've probably heard of the health benefits of a mushroom formula, but do not know much in details. Well, Medicinal mushrooms are known to possess healing and life-giving properties. However, there are different types of mushrooms and each of them has its benefits. Let us look at three important mushrooms and how they can benefit you. Turkey Tail Mushroom The turkey tail mushroom has shown great promise as a powerful immune system booster. If this is your first time of hearing about this mushroom, you will want to pay keen attention to its benefits. The Turkey Tail Mush room has the power to fight off foreign invaders due to its anti-vital and microbial properties. The world we live in is full of toxins, bacteria and viruses, but when our body's immune system is working effectively, it can protect you from dangerous invasions. Furthermore, the turkey tail mushroom is can help your body to fight off the growth of cancerous tumor cells. It is therefore, a weapon against sickness and cancer. Maitake Mushroom This is an edible species that is commonly found in form of extract today. It contains beta-glucane, which helps to strengthen the immune system as well. When you take this extract regularly, it will boost your immune system and prevent the entrance of foreign bodies that causes infection. Also, Maitake mushroom helps to regulate blood sugar levels in the body. Therefore, it is good for people with diabetes and also helps to prevent similar illnesses. Reishi Mushrooms Today, the Reishi mushroom is now available as a dietary supplement. It can be added to coffee and tea. Like other mushrooms, it helps to boost the immune system and promote good health. The Reishi mushroom also act as an antioxidant by eliminating Hydroxyl free radicals and improving your ability to use oxygen. More so, it is effective at lowering blood pressure and cholesterol levels.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2794) Green Coffee Bean Extract
Date:
November 22, 2012 10:31 PM
Many studies have been carried out to establish the health benefits of Green coffee bean extract for several years. It was just in 2012 that some group of scientists revealed a particular study that demonstrated Green Coffee Bean Extract‘s effectiveness in contributing to weight loss. Leading this study was Dr Joe Vinson, a scientist from the University of Scranton. On the same note, sixteen over-weight people also participated in the study. They were all given varying doses of the Green Coffee Bean Extract for a period of 22 weeks. These participants lost around 17 pounds when the study ended. They did not report any side effect. Moreover, they were under no exercise plan or diet change during the period of study. The coffee powder that people normally use is prepared after roasting some green coffee beans. The extract is obtained from green coffee bean at a temperature of about 70°C for 2 hours using 70 percent of ethanol. A green coffee bean extract is a yellowish brown hygroscopic powder that has high polyphenols levels referred to as Hydroxycinnamic acids, which contains caffeic and chlorogenic acids. Green coffee bean extract and weight loss A Japanese scientist, known as Hiroshi Shimoda, did a research about the green bean extract and discovered that it facilitates body weight loss. The weight loss is brought about by some two natural chemical compounds found in the green coffee bean. Since coffee beans are not roasted, they still have their natural chemicals that can otherwise be lost if they are roasted. The two natural chemicals are chlorogenic acid and caffeine which jointly lead to loss of weight. The caffeine in coffee works by stimulating the release of fatty acids from the fats stored inside the body. The chlorogenic acid, on the other hand, helps the liver to process the released fatty acids thus resulting in weight loss. If one consumes 1kg of food containing 10g of green bean extract daily for 14 days, then the increase in weight can be suppressed by about 35 percent. Other Health Benefits of Green coffee bean extract Anti-aging Benefits The chlorogenic acids in green coffee bean destroy any free radicals formed within the body through metabolism. If such free radicals are left, they can destroy the cell membrane and trigger some ageing symptoms. By destroying such harmful radicals, green coffee bean extract actually slows down the natural aging process. Some studies also reveal that the absorption capacity for oxygen radicals by the green coffee extract is twice that of green tea or grape seed extracts. Reduce Blood Pressure Animal research also reveals that chlorogenic acids in the green bean extract helps in alleviating high levels of blood pressure. Considering the results of this particular study, some research was further conducted on human beings. This experiment, performed on people with mild hypertension, revealed that the consumption of the green coffee extract supplement contributed in lowering high blood pressure levels. When a dose of about 185mg of green coffee extract supplement was consumed, the extract proved quite effective in reducing symptoms of hypertension. Hence they are often used for the treatment of the same.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2734) What Are The Health Benefits Of Cascara Sagrada?
Date:
October 09, 2012 08:37 AM
Cascara sagrada is considered to be a herbal tree which is famous for its laxative properties. Aside from this fact, there are other health benefits of this herb. Read on and find out more about the benefits of this deciduous shrub. The Health Benefits of Cascara Sagrada 1. This particular herb is famous in treating chronic constipation. It does not provide fiber; it irritates the lining of the bowels as well as increases the rate of digestion. Dried and aged barks of this herb are used in treating chronic constipation. This herb contains Hydroxyanthraquinone glycosides called cascarosides which induces the large intestine, thus increasing muscular contraction. 2. Another health benefit of this herbal shrub is its detoxifying properties. It is believed that the formation of toxic materials in the colon can cause colon diseases. Good thing this herbal shrub can help in cleansing and restoring the natural tone of your colon. 3. Aside from the ones mentioned above, Cascara Sagrada is also known to increase the secretions from pancreas and liver. With this, it will promote overall health and wellness when it comes to your digestive system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2680) How does 5-HTP Help the Brain?
Date:
May 28, 2012 08:17 AM
5-HTP 5-HTP is the abbreviation of 5-Hydroxytryptophan, an amino acid that converts tryptophan into serotonin and melatonin. Serotonin is a neurotransmitter that helps with the regulation of sleep, mood and appetite, and it is found in the stomach or the CNS. 5-HTP is mainly obtained from animal products especially red meats and eggs. Fish and dairy products are also rich in this amino acid. Vegetarians get this compound from pumpkin seeds, oats, potatoes, peanuts and dried dates. Due to its ability to regulate the amount of serotonin and melatonin in your body, 5-HTP regulates the functioning of your brain. The following are the health benefits of this compound: It fixes anxiety Anxiety and panic disorders are some of the most popular mental disorders that can be cured using 5-HTP. These two illnesses occur when your body experiences a deficiency of serotonin. Therefore, taking supplements of this amino acid reduces your chances of developing any or both of these conditions. It treats insomnia Insomnia is a problem that affects the quality of your sleep. Sleep is normally regulated by your brain. Every night, your brain releases receptors that lead to the five stages of a sleep cycle. If your brain fails to release the appropriate receptors, you cannot enjoy a complete sleep cycle. In addition, Melatonin is the hormone that induces sleep and therefore its absence leads to poor sleep quality. The production of sufficient melatonin therefore boosts the quality of your sleep and helps with the treatment of insomnia. It helps relieve the symptoms of depression Your mood is controlled by the neurotransmitter serotonin. The absence of this neurotransmitter leads to the development of a depressed mood. However, the availability of 5-HTP in your body leads to the production of sufficient serotonin thus restoring your happiness. It also treats eating disorders especially among young children Your brain controls your levels of appetite. Serotonin is specifically in charge of this function, and therefore its deficiency in your body leads to a disruption in your appetite mechanism. Most people who have this problem often tend to eat lots of sweet foods that are rich in empty calories, high carb and junk food. This often leads to obesity and overweight. However, taking 5-HTP supplements restores your appetite mechanism thus protecting you from eating disorders and subsequent complications such as obesity. It is a natural pain killer 5-HTP enhances the production of endorphins, thus helping your body overcome pain and migraines. Chronic headache is often associated with low levels of serotonin, and this can be reversed by taking sufficient 5-HTP. Serotonin has a calming and soothing effect on the central nervous system, and therefore the sufficient release of this neurotransmitter helps ease pain on the head. 5-HTP helps relieve the symptoms of fibromyalgia Fibromyalgia is often accompanied by chronic pains and aches that can be relieved by taking sufficient supply of 5-HTP. This is because this amino acid helps with the secretion of serotonin, which helps ease such pains and aches. It is therefore important for you to ensure that you have sufficient supply of 5-HTP in order to enhance the functioning of your brain.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2649) What Form Of Calcium Is The Best Calcium?
Date:
February 21, 2012 11:21 PM
Best Calcium Manypeople these days want to know which form of calcium is the best form of calcium. Calcium happens to be an essential nutrient for the body. However, since this nutrient serves a variety of purposes, therefore, it can be a bit tricky to determine which form is the best. There, in fact, might not be a single best form of calcium but probably quite a few, depending on what the calcium is needed for. Calcium Complex (MCHA) Microcrystalline Hydroxyapatite Everyone is aware that calcium is the building block of bones and for the treatment of a bone-related condition like osteoporosis; Calcium Complex (MCHA) Microcrystalline Hydroxyapatite is the best calcium. Supplements containing this form of calcium have, in fact, been proven to be effective at increasing bone density and reversing osteoporosis. Among the biological forms of calcium available, what makes MCHA one of the best forms of calcium for treating osteoporosis and increasing bone density is because it is excellent absorbed by the body. Calcium carbonate is often recommended by medical doctors because a very minimal amount of pills need to be taken. Calcium Carbonate For those who do not want to use a form of calcium derived from a biological, animal source and are, in fact, in search of the best calcium for the maintenance of bones, then Calcium Carbonate is perfect. This form of calcium is the second best in regards to absorption by the body. Calcium Carbonate is often recommended by medical doctors because a very minimal amount of pills need to be taken. Calcium Carbonate supplements can be found quite easily and they are mostly affordably priced. Chelated Calcium Supplementing calcium also becomes necessary for anyone who has recently undergone Bariatric surgery. While Calcium Carbonate can also be used in such a situation, however, the best calcium in this case would be Chelated Calcium. Chelated Calcium is a form of calcium that is used in combination with beneficial amino acids. In comparison to Calcium Carbonate, research has shown that Chelated Calcium is a far more biologically available form of calcium. However, the dosages of this calcium that need to be taken are generally quite large. Above all, Chelated Calcium supplements can be quite costly too. Calcium Citrate Calcium Citrate is an ideal alternative to Chelated Calcium, in fact, it is another form of Chelated Calcium, but the supplements that contain this form of calcium are usually more inexpensive. Not only this, those who choose to use this form of calcium will also get to take lower dosages. Calcium Citrate is a form of calcium that is acid based and is quite capable at supplementing the body with calcium since it is quite effectively absorbed. Since no additional stomach acid is required for the absorption of this form of calcium, therefore, Calcium Citrate at just about any time. There are many other forms of calcium that are quite ideal for the body as well and can prove to be beneficial as well. This is the reason that those in search of the best calcium will come across numerous choices and some of the best ones were mentioned here.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2588) What Is The Difference Between DGL Licorice and Regular Licorice?
Date:
February 13, 2012 07:35 AM
Manypeople these days have heard of the name “Licorice” because of the various chewy rope-like flavored confectionaries or candies that are widely available these days and taste amazingly sweet. However, most of these people have never paid attention to what these candies are made of. The fact is that these candies contain the extract from Licorice roots. The Licorice roots are yielded from the Licorice or the Glycyrrhiza glabra plant. The extract from these roots has been used from quite a long time, both as a food ingredient and as an herbal remedy. However, the Licorice root also has a derivative form known as deglycyrrhizinated or DGL Licorice. Both of these products offer numerous benefits and when taken under medical supervision they can effectively help in treating a variety of medical ailments. Licorice plants originate from the Middle East, where harvesters peel the root out of the plant, dry them, cut them and eventually the Licorice roots arrive in other countries. Glycyrrhetic acid, cumestan derivatives, Hydroxycoumarins, isoflavonoids, triterpene saponins, etc. are some of the active constituents contained in regular Licorice roots. One problem with using Licorice roots was that it was generally recommended that people use the extract from the root only under medical supervision. This was mostly because of the Glycyrrhetic acid contained in the root. Thus, while DGL Licorice is indeed derived from Licorice root, however, glycyrrhetic acid is removed during the preparation of DGL. Therefore, this form of Licorice can be consumed much more safely without any worries. Furthermore, ulcers the esophagus, in the mouth and the stomach lining in the small intestine are more effectively treated with this derivative form of Licorice. DGL Licorice is presently widely available as chewable tablets, mouthwashes and even teas; therefore, people have a few choices as to how they want to take the derivative extract that comes from the root of the Licorice herb. DGL is actually an effective treatment for digestive problems like heartburn and GERD or gastroesophageal reflux disease, ulcer, etc. What makes this derivative extract so beneficial is that the protective factors of the digestive system are accelerated and/or stimulated by its mechanism as a result of which the internal lining of the intestines in the stomach are protected against the formation of ulcer. Unlike typical antacids and anti-inflammatory drugs that basically neutralize or suppress gastric acid, the DGL extract functions quite differently. Apart from helping treat the mentioned digestive problems, even minor skin conditions such as carbuncles, eczema, minor cuts and wounds can also be effectively treated by applying ointments that contain DGL. Apart from being better than the regular extract obtained from the Licorice root, the DGL derivative is also far more effective anti-ulcer compound in comparison to the typical medications that are available these days. It is usually advised that DGL should be taken at least twenty minutes before meals. And usually 2 to 4, 400 mg tablets are the standard dose of DGL that can be taken for chronic cases of ulcer. Therefore, those who are considering using Licorice root extract should instead go for DGL Licorice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2574) What is Vitamin Methylcobalamin B-12?
Date:
February 10, 2012 11:52 AM
Among the vitamin supplements presently available in the market, Vitamin B12 supplements are ones that a majority of people tend to excessively overlook. However, people do not know that this particular B vitamin is essentially need by their body to ensure that the nervous system continues functioning healthily, good DNA is produced and energy levels are maintained. What is Vitamin Methylcobalamin B-12? Vitamin B12 actually exists in four different forms namely Adenosylcobalamin, Cyanocobalamin, Hydroxycobalamin and Methylcobalamin. Among these forms of vitamin B12, the one that is most highly absorbed by the body is Methylcobalamin. This coenzyme form of vitamin B12 is considered biologically active. Since the deficiency of vitamin B12 can result of vitamin B12 can cause many problematic symptoms. The deficiency of B12, however, can be avoided with the consumption of Methylcobalamin B12 since it is absorbed by the body at a maximal rate. The body does not need to excesively metabolize this form of vitamin B12 in order to make it safe to be absorbed; therefore, it is almost instantly used up by the body. Typically the foods that vegans eat does not supply them with enough vitamin B12 from their diet, therefore, taking this coenzyme, biologically active form of vitamin B12 can help them cover up its deficiency. Why is Vitamin Methylcobalamin B-12 So Necessary? As mentioned earlier, the overall health of the body somewhat depends on the consumption of vitamin B12 as well. Similarly, anemia, nausea, lethargy, etc. are some health problems that can be caused because of the deficiency of vitamin B12. There are many other uses of vitamin B12, which can be more effectively fulfilled by Methylcobalamin. Carbohydrates, protein and sugar are effectively converted into energy with the help of this particular vitamin. This helps people avoid getting easily tired and worn out during the day.Red blood cells are formed with the help of this vitamin.This vitamin is needed by white blood cells so that they can ensure the immune system is functions efficiently.The vitamin is used by nerve cells so that they can keep their fatty layer preserved.Cellular regeneration is promoted by this vitamin. People will also get easily fatigued, experience shortness of breath and feel numbness in their feet and hands if their body is deficient of vitamin B12. People can even suffer from pernicious anemia if their body becomes significantly deficient of this vitamin. The level of this vitamin in the body can also be lowered if people have undergone some digestive-related surgery or have used some drugs to combat gastric conditions. Typically, B12 injections containing methylcobalamin are recommended by doctors to patients whose bodies are in need of this vitamin. However, this particular form of the vitamin is also available in the form of supplementary tablets that are placed under the tongue until they dissolve up completely and are absorbed by the body. Vitamin B12 is therefore considered among the nutrients that the body essentially needs and it can be far more beneficial if people consume Methylcobalamin instead of the regular vitamin B12.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2569) What is the Difference between 5-HTP and Tryptophan And How Does It Help Sleep Patterns?
Date:
June 22, 2011 11:00 AM
5-Htp and Tryptophan to Sleep Better, Feel Better5-HTP, short for 5-Hydroxytryptophan, is an organic compound that naturally occurs in the human body. It is a metabolite of tryptophan, and as such it serves as a chemical intermediate in the synthesis of the neurotransmitters serotonin and melatonin. It is sold over the counter in many countries primarily as a dietary supplement. In addition, it is used as an antidepressant, appetite suppressant, and sleep aid. Tryptophan to 5-HTP Tryptophan is best known as an essential amino acid that must be obtained from the diet. Popular sources of this amino acid are eggs, cheese, pork, turkey, chicken, beef, salmon, and white flour. In one metabolic pathway, tryptophan is processed into vitamin B3, or niacin. In a completely different pathway, it is metabolized into serotonin and then melatonin, both of which are processed from 5-HTP. Also known as oxitriptan, 5-HTP has been the subject of numerous studies in the past few decades. Being the immediate precursor of serotonin, regular intake has been observed to specifically increase the production of serotonin, the reason why it has been a very important amino acid widely utilized in the treatment of depression. On the other hand, tryptophan is utilized by the body in many ways. 5-HTP to Serotonin Supplementation of tryptophan has also been used as a therapeutic treatment for depression. It is an alternative to antidepressants and stimulants, especially for patients deemed unresponsive to conventional treatments. Regular intake of this amino acid is recommended for the sole purpose of raising the levels of serotonin. But in order to do so, tryptophan must be metabolized into 5-HTP first. Serotonin is often referred to as the happiness hormone, inasmuch as this neurotransmitter is implicated in several chemical reactions that contribute to physical well-being. For example, the perception of hunger is triggered by low serotonin levels. Not surprisingly, serotonin is the target of many drugs, such as antidepressant, anxiolytic, antiemetic, anti-migraine, and antipsychotic drugs. Serotonin to Melatonin It is a widely accepted fact that serotonin produced and released outside the central nervous system does not cross the blood-brain barrier, and thus it does not have the effect of serotonin found in the brain. That being said, its precursors, tryptophan and 5-HTP, can. For this reason, tryptophan and 5-HTP makes a viable candidate in increasing the levels of serotonin in the central nervous system. Melatonin is synthesized from serotonin by a short metabolic pathway that stems from the synthesis of 5-HTP. Proponents argue that 5-HTP supplements work better than tryptophan due to the fact that the former is the immediate precursor of the neurotransmitters of concern. Furthermore, 5-HTP readily crosses the blood-brain barrier whereas tryptophan is subject to different metabolic pathways. 5-HTP works as an appetite suppressant since it makes serotonin more available outside the nervous system, especially in the digestive tract. By so doing, it promotes the synthesis of melatonin, which induces sleep. It also makes a reliable antidepressant as it increases serotonin levels in the central nervous system. Grab Some Tryptophan or 5-HTP today and feel better, sleep better right now!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2346) How Does Zinc Boost the Immune System and What Else Does this Mineral Do
Date:
May 02, 2011 01:58 PM
Zinc And Good Health!Zinc is considered a transition metal in general, and as such one of the most abundant transition metals in living organisms, including human beings. It plays a central role in the molecular structure of proteins, which is indispensable in catalytic activities of over a hundred enzymes. These proteins belong to all enzyme classes and have far-reaching effects on the human body, notably in the immune system. In the past few decades, the scientific community has unearthed countless chemical reactions that take place inside the human body. A number of these reactions necessitate the presence of zinc. While zinc is considered toxic in high amounts, it is classified as an essential trace mineral, which means it has a daily value. A deficiency in zinc has serious effects on growth and development as implicated in the life cycle of cells. Stabilizes Cellular Structures Zinc is a trace mineral that is quite pervasive at the cellular level as all cells have zinc demands. This dietary element keeps cells in prime condition and maintains the health of cell organelles. For one, zinc is required to stabilize ions that functions as interaction modules responsible for binding DNA, RNA, and other particles found within cells. The absence of zinc in cells will cripple these activities. The complete absence of this trace mineral is improbable, but low levels of elemental zinc in the body have been observed to have serious effects on cellular health. The capacity of cells to contain radical damage depends on the availability of zinc. Depleting levels of zinc result in an impaired antioxidant defense and greater susceptibility to free radicals and other reactive oxygen species. Induces Enzymatic Reactions Enzymes are proteins that play functional roles in the metabolism of bioactive compounds. They are categorized into many classes, depending on their catalytic functions. These functions are vital as they are one of the mechanisms in the employ of the body to sustain homeostasis. Some classes are involved in immune responses in the prevention of disease and the alleviation of chronic disorders. All classes of enzymes are affected by the metabolism of zinc one way or another, with over a hundred requiring the direct involvement of zinc to induce catalysis. Zinc is of special note in a chemical reaction called Hydroxylation, a process that helps cleanse the body of toxins. With Hydroxylation, zinc participates in the conversion of lipid-soluble substrates into water-soluble products ready for excretion. Modulates Immune Responses The human body utilizes zinc in many different metabolic pathways that influence the processes needed for prompt immune responses. In the case of common infections such as colds and flu, zinc curtails severity of symptoms and raises immune responses to optimum levels. More importantly, healthy levels of zinc enable the body to take on preventative measures against diseases. Remember even though zinc is an important mineral, to much can cause problems as well. Do not exceed 150mgs daily for extended periods of time to maintain safe levels of zinc. I suggest 15mg to 75mg daily.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2286) Can Olive Leaf Boost My Immune System - answer is Yes
Date:
April 06, 2011 03:01 PM
Olive Leaf And Your HealthOlive leaf is highly prized for its antimicrobial properties in booth food and supplement industries. For centuries, the leaf of the olive tree has been utilized as a natural antibiotic. It has become the subject of modern day scientific research in the past few years, and preliminary studies appear to be in favor of its age-old claims. In addition, it is now known to modulate immune responses and display potent antioxidant activities. Olea europaea may be best known for its long association with Mediterranean cuisines although cultures around the world have also used various parts of the plant as flavor enhancers. Its medicinal value continues to gain prominence as recent studies point to the health benefits of the organic compounds it contains. Olive leaf is identified to be an excellent source of the phytochemicals Hydroxytyrosol, oleuropein, and oleocanthal, all of which are known for their antioxidant and anti-inflammatory properties. In fact, fresh olive leaves are widely accepted to have an antioxidant content that is 400 per cent higher than vitamin C, that’s double the antioxidant capacity of green teas. Fights Bacterial and Viral Infections Olive leaf is antiseptic in nature. It was an important ingredient in poultices used to treat war wounds in the ancient world. Elenolic acid is an organic compound naturally occurring in olive leaf, which is under scrutiny for its antibacterial and antiviral properties. This compound is described to be both bactericidal and bacteriostatic, which means it is directly involved in killing bacterial strains and at the same time interferes with bacterial cellular metabolism. In addition, the antiviral properties ascribed to olive leaf are attributable to its ability to viral protein synthesis necessary for viral replication. This explains why it is effective in the treatment of many known infections, such as candidiasis, shingles, herpes, and Epstein-Barr virus infectious mononucleosis. It has also been reported to reduce the symptoms of colds and flu and shorten their duration. Scavenges Reactive Oxygen Species The natural antioxidants found in olive leaf are believed to be the most powerful antioxidants in the market, and as such often marketed as anti-aging. Antioxidants are indispensable in the prevention of the tissue damage caused by reactive oxygen species, or ROS. Free radicals, the best known ROS, are among the group of by-products of oxygen metabolism in the human body. They are also deployed by cells in response to invasive pathogens. Each cell does have its own antioxidant defense, but an imbalance between endogenous antioxidants and ROS is quite common. Chronic stress and physical fatigue are thought to compromise the antioxidant defense of the body, which is restored by antioxidants found in the diet. Boosts the Innate Immune System Furthermore, olive leaf strengthens the innate immune system. Its proponents believe that regular intake contributes to the non-specific responses of the immune system, such as the production of neutrophils during inflammation. This type of white blood cells is often the first to engage with pathogens. By speeding up their releases, olive leaf prepares the body against infections. If you want an Immune Boost, Give olive leaf a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2266) Control Depression And Appetite With 5-HTP
Date:
March 05, 2010 12:21 PM
Considerable research has been done on 5-HTP as to its safety and use in weight loss and depression. 5-HTP is made from tryptophan, which is a natural amino acid that is found in foods. Tryptophan is an essential amino acid, meaning that it cannot be produced within the body. Therefore, it must be obtained from food, specifically, proteins. 5-HTP is convereted to an important monomine neurotransmitter called serotonin within the liver and brain. Neurotransmitters are chemical messengers that transmit signals between neurons in the brain. Serotonin, which is a neurotransmitter that closes the gap between neurons, is essential for many bodily functions. It is believed to play a role in both depression and obesity. Unlike serotonin alone, it can cross the blood-brain barrier. This makes it possible for the brain to manufacture more serotonin. 5-HTP may actually help to promote the production of serotonin, which makes more available in the body. Research has determined that increasing amounts of 5-HTP can help deal with weight loss and depression. 5-HTP is made from tryptophan, which is a natural amino acid that is found in foods. 5-HTP may be able to revolutionize the treatment of emotional and physical problems that are related to the lack of serotonin. This amino acid has been used effectively in Europe for decades. Recent clinical studies that therapeutically administered 5-HTP confirmed that this supplement is effective in treating depression, fibromyalgia, binge eating, chronic headaches, and insomnia.
Recent research determined that a group of women given 5-HTP ate less than those women who were given a placebo. Weight loss through appetite control was linked to the intake of 5-HTP. Women who took 5-HTP over a five week period lost an average of three to four pounds. Other studies on humans have produced the same results. It seems that 5-HTP provides a feeling of fullness, causing women to eat less. Depression has been linked to low levels of serotonin. 5-HTP has been shown to improve mood swings and depression by elevating serotonin levels in the body. One study compared 5-HTP supplementation with the use of Prozac, which works by increasing serotonin levels in the brain. In both cases, there was fifty percent improvement in depression. However, those who were taking 5-HTP showed a higher tolerance for the treatment and had a lower failure rate. Those suffering from obesity and depression may be helped by the use of 5-HTP. This natural supplement may be able to help reduce the appetite and improve moods. 5-HTP acts as an alternative to prescription drug therapy, which is well-known for the adverse side effects that it provides. It is important to consult your health care provider before using this, or any other supplement. For more information on the many beneficial effects provided by 5-HTP, please feel free to contact a representative from your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2129) Garcinia, Hydroxycitric acid and weight loss
Date:
December 03, 2009 01:10 PM
Garcinia is a little-known fruit that can be found growing extensively in India and Thailand. Used for centuries as a condiment, garcinia is also known as Malabar tamarind or Gorkapuli. The garcinia fruit is about the size of an orange and orange in color. However, it looks similar to an acorn squash in appearance. With approximately two hundred different species of garcinia, only few contain the needed component necessary for herbal health. Scientists have identified the natural compound found in garcinia to be Hydroxycitric acid, which can help to curb appetite, reduce food intake, and slow the body’s fat production.
Hydroxycitric acid, that active component in garcinia, is similar to the citric acid that is found in citrus fruits like oranges, lemons, and grapefruit. The garcinia fruit is actually composed of about fifty percent Hydroxycitric acid. This acid seems to have potent fat-fighting properties and is known for its ability to block the formation of fatty tissue, which results in less storage of fat. The rind of the garcinia fruit contains high amounts of Hydroxycitric acid, which inhibits citrate lyase, which is an enzyme require to manufacture body fat. The Hydroxycitric acid combines with citrate lyase, which leaves less of the enzyme available to form body fat and speeds up the fat-burning process. Some studies have found that fat production may actually be reduce by as much as seventy percent when taking hyroxycitric acid. Garcinia has been found to be beneficial in curbing the appetite, which aids in weight control and obesity. One study on animals found appetite reduction in lean and fat rats and mice. The animals ate less, and when hyroxycitric acid was added to their diets, their body fat decreased, but body protein was unaffected. Garcinia is also thought to help burn fat through thermogenesis. When there is not enough thermogenic activity, weight gain can result. The thermogenic activity in garcinia is responsible for helping to increase heat production, specifically in brown fat, which is the body fat surrounded by blood vessels and energy cells. Brown fat is harder to lose because it requires more heat to burn. The fruit of the garcinia plant is used to provide anorectic, anticatarrhal, astringent, demulcent, and thermogenesis properties. Primarily, garcinia is extremely helpful in dealing with excessive appetite, obesity, and weight-related conditions. Look to your local or internet health food store for this and other great products to help with weight loss.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2114) Pau d'arco Bark
Date:
November 10, 2009 11:23 AM
Pau d'arco is found growing in a tree high in the Andes and can weather the worst storms because of its hard wood and deep roots. This herb is found in the inner bark of the red lapacho tree. Most of the trees surrounding this tree eventually become covered with spores, which lead to fungus, and this eventually kills the trees. However, the red lapacho seems to be able to resist the spores. This may be a contributor in pau d'arco's ability to heal the body and resist disease.
There seems to be some evidence of antitumor properties in pau d'arco. Many individuals have taken this herb when they are undergoing radiation and chemotherapy. Pau d'arco helps to strengthen the body and help prevent the side effects that are associated with cancer treatment. Additionally, this herb seems to be a powerful alterative and blood builder. It has the ability to increase the hemoglobin and red corpuscles that are found in the blood. It gives the body a greater vitality by increasing its resistance to disease. Pau d'arco seems to be responsible for giving the body energy and strength to defend itself and resist disease. The herb is also believed to help inhibit the growth of tumors and increase the growth of normal tissue. Furthermore, pau d'arco herb is used to aid in the assimilation of nutrients and the elimination of waste matter. Studies have found that a component of pau d'arco, quinine lapachol, has antimicrobial and antiviral properties. The herb also seems to have an antitumor effect without any toxic side effects. Additional components include beta-lapachone, Hydroxyl-napthoquinone, alpha-lapachone, and xyloidone. These are effective against numerous viruses, bacteria, and fungi, including herpes, influenza, poliovirus, and many others. A researcher at the National University of Tucuman in Argentina, Dr. Theodoro Meyer, discovered the substance xyloidin. This substance is able to kill viruses. Xyloidin is also beneficial in inhibiting the causative agent of dysentery, tuberculosis, and anthrax. Pau'd arco is available at your local or internet health food store at discount prices. Look for name brands like Solaray, Source Naturals, and Natures Plus to ensure quality and purity of the product you purchase.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2111) Fight Cold Sores And Build Collagen
Date:
April 29, 2009 10:18 AM
Lysine is an essential alpha-amino acid, in that it cannot be biosynthesized by the human body, and therefore must be taken in your diet or as a supplement. It is synthesized in plants from aspartic acid, and metabolized in the body to produce acetyl-Coenzyme A (acetyl-CoA). Before discussing its action on herpes, we shall first have look at how Lysine helps with the formation of collagen. Collagen is a protein that is produced in the body from lysine and proline, another amino acid. In fact the primary role of amino acids in your diet is as building blocks to form the much larger protein molecules. Collagen is fibrous, and forms the connective tissue such as cartilage, ligaments, tendons, blood vessels and skin. Even the external parts of the ears. It literally holds our skeletons together, and wraps the whole body up in skin, so if we had no collagen we would literally fall apart! Collagen is also used by body cells to form the matrix that the body cells use to attach to each other and is one of the most important types of tissue in your body. It is so ubiquitous that over 30% of the protein contained in your body is collagen, and it is designed for its structural strength as opposed to its ability to take part in chemical reactions as other proteins are. Lysine and Vitamin C are essential for the maintenance and formation of collagen. There is not a lot of lysine in collagen - only about 4%, but it is very active in the cross-linking that forms the fibrils of collagen. Fibrils are the hair-like structures formed in a triple helix arrangement by three protein chains twisting round one another. The fibrils are bundled together in a straight line that has amazing tensile strength. The tensile strength of collagen is, weight for weight, stronger than steel! In order for lysine to take part in this process effectively, some molecules have to be Hydroxylated and others oxidized, forming aldehydes. Things can go wrong here, and deficiencies in the metabolic process can lead to some heritable conditions, or diseases of connective tissue. Among these are lathyrism, Cutis-Laxa and the Menkes kinky hair syndrome. However, lysine is a very versatile amino acid, and not only is it necessary for the biosynthesis of all proteins, but is also heavily involved in the production of enzymes, hormones and antibodies. It is an important component of the calcium absorption process, and also, as previously stated, can be used in the treatment of herpes simplex. This form of herpes is known commonly as 'cold sores', and is a result of the activity of the herpes virus. Viruses do not reproduce in order to ensure the 'continuation of the species', but replicate. In order to achieve this it requires the help of another amino acid, arginine. This is a common amino acid whose sources include grains, seeds, peanuts, raisins and chocolate. Lysine and arginine competes for the absorption and entry of tissue cells, and reduces the strength of arginine, so preventing the growth of herpes. For this reason a supplement of lysine can be used to reduce the effects of the herpes simplex virus, and lessen the symptoms of the cold sore. However, it is not only cold sores but other forms of herpes that lysine can help to relieve. Herpes zoster is a virus that causes shingles. This virus is generated by the reactivation of the dormant varicella-zoster virus left in the tissues after chickenpox. It is a recurrent condition, and lycine can help to reduce recurrences as well as its severity. Apart from being an effective defense against herpes, and forming collagen, the amino acid imparts several other benefits to the human body. Among these is osteoporosis. L-lysine is involved in calcium absorption in the intestine, and also helps to reduce the loss of calcium in the urine. In osteoporosis we have to try to make every calcium molecule ingested in the diet to be incorporated in the bone structure. L-arginine can work with lysine to enhance the activity of the body cells that produce bone. Canker sores are often mistaken for cold sores, but they are actually quite different. They are small sores inside the mouth, and appear in the form of very painful ulcers. The cause is unknown, but is believed to be a virus, and lysine appears to help the condition. Although there have been no proper clinical tests carried out on its use as a remedy for canker sores, lysine appears to help, and a supplement is recommended as a treatment by many doctors. It will do no harm, and anybody suffering from these tiny but painful sores will try anything. Although lysine deficiency is rare, it can occur, particularly amongst those observing a vegetarian macrobiotic diet, and also in athletes who frequently undertake vigorous exercise, especially with too little recovery time. The effects of a deficiency are fatigue, nausea, appetite loss, anemia, slow growth and kidney stones. The latter is likely due to a failure to absorb calcium, that L-lysine promotes, and the formation of calcium oxalate and other insoluble salts in the kidney. Dietary sources include beans and other legumes, and although it should be available in cereals, baked foods and doughnuts, for example, the carmelization of sugars binds the lysine to the sugar, and so reducing its bioavailability. However, you can also get it in cheese, eggs, tofu and red meats. If you are taking an arginine supplement, you should consult your physician prior to taking lysine. The reason for this is that lysine and arginine share biochemical pathways, and arginine can reduce the effective concentration of lysine. However, it has not been tested by the FDA, nor approved, and any use is at your own risk. This risk appears to be very small, although its manufacture is not regulated. However, do not let this bother you: the proof of the pudding is in the eating as they say. Many have found lysine to be effective with collagen or herpes problems, and a supplement of between 3,000 and 9,000 mg per day is recommended for those with herpes viral infections. It is not recommended for children under two years old. Lysine is available at your local or internet health food store at discount prices. Look for name brands to ensure purity and quality of the product you purchase. Another Great Cold Sore Remedy is Red Marine Algae!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1998) Detoxify With L-Citrulline
Date:
April 13, 2009 03:51 PM
L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood. It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea. The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea. The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-Hydroxyarginine, and then into L-citrulline with the release of nitric oxide. So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells. Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred. In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure. Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery. During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow. It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels. It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid? Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise. Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted. Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.
L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1993) Huperzine And Memory
Date:
December 04, 2008 01:20 PM
Chinese club moss goes by the name Huperzia serrata, and gives its name to the sesquiterpene alkaloid it contains: huperzine A. This alkaloid has been found to be a superstar in the arena of brain-saving treatments for conditions such as Alzheimer's and age-related senility. Studies in China have found up to 60% improvements in the cognitive functions of such patients, and its potential has been recorded in the Journal of the American Medical Association. This is no mere folk remedy, and is the subject of serious study. Known as Qian Ceng Ta, Chinese club moss has been a part of traditional Chinese medicine for centuries for the treatment of fever and inflammation, which is not surprising considering that most plants contain antioxidants and anti-inflammatories. However, what is unusual is the fact that it has also been found effective in treating some forms of dementia and depression, and also helps to reduce the incidence of panic attacks in those susceptible to them. Not only that, but the plant has been found to possess diuretic properties, and a reduction in the swelling associated with water retention could also help to reduce the pain and other effects of swelling and inflammation. However, for now it is its effect on the brain that we are concerned, and research has indicated the likely mechanism by which huperzine A works. Huperzine is an enzyme inhibitor - specifically inhibiting the enzyme acetylcholinesterase that breaks down acetylcholine, a neurotransmitter involved in the processes of memory, learning and mood. Outside the brain, it is involved in the movement of skeletal muscle tissue as well as in the regulation of cardiac and other smooth muscles such as those of the blood vessels. When acetylcholinesterase (AChE) attacks acetylcholine (ACh), the latter attaches to a chemical site on the enzyme where it is then destroyed. It is a deliberate function of the body, designed to terminate a synaptic transmission. The purpose of a neurotransmitter is to allow the transmission of an electrical impulse form one nerve cell to another over a gap between them known as a synapse. Once the transmission has been completed, the enzyme can destroy the neurotransmitter, and then another takes its place. In fact one molecule of AChE can destroy around 5,000 molecules of ACh. However, with age and for other reasons, these neurotransmitters can become depleted so that it becomes increasingly more difficult for brain cells to communicate with each other, and their destruction becomes undesirable. There are drugs available to help prevent this happening (e.g. donepezil, galantamine and tacrine), and so help to improve the memory and mental function of people as they grow older or contract conditions such as Alzheimer's disease. Huperzine A has been found to take up the site in the acetylcholinesterase molecule that would normally have been used by the acetylcholine, and so save it from destruction. The more Huperzine A molecules present, the more acetylcholine available to pass messages between brain cells, and the stronger the cognitive function of the subject or patient. The pharmaceutical drugs mentioned in the previous paragraph work in exactly the same way. This is a very specific reaction, one molecule adopting exactly the same space as the other, and has been proved scientifically by comparing the physical shapes of the two molecules. It's just like a jigsaw puzzle, where only one piece can fit into each position. Except here there are two: Huperzine A and acetylcholine both fit into the exact same place in the chemical structure of the acetylcholinesterase molecule. The biochemistry of the reactions involved is very complex, and shall not be discussed here, but the upshot is that Huperzine A can do exactly the same job as modern drugs to avoid this Hydroxylation of the ACh needed for the proper functioning of your brain. In fact, clinical trials have indicated Huperzine A not only to be comparable in effect to the drugs current used, but also likely safer with respect to the possible side effects. This has still to be confirmed, but the National Institute on Aging is currently carrying out a trial to evaluate this claim in tandem with its effect on Alzheimer's disease. It has also been examined at Harvard University for its effect on epilepsy on patients with whom alternative pharmaceutical treatments have been unsuccessful. Another suggested benefit of Huperzine A is that it is an NMDA (N-methyl D-aspartate) receptor antagonist that provides protection against damage to the brain by an excess of glutamates, and that it can also help to protect nerve cells from damage. Since NDMA is responsible for the transmission of some types of pain, the antagonist can also act as an analgesic. There are other benefits that Chinese club moss can provide, and myasthenia gravis is one of them. Although relatively rare, this is a serious condition in which acetylcholine receptors are deactivated on muscle cells. This is achieved through the autoimmune system malfunctioning and creating antibodies against the receptors, and the end result is paralysis and respiratory failure. Huperzine A reduces the AChE available and so might possibly enable the acetylcholine to work more effectively and delay or even stop the deterioration of muscle function. When people hear of muscle paralysis they frequently forget that breathing requires muscle function, as indeed does your heartbeat. This is currently surmise, and studies are being carried out to determine whether or not this usage of Huperzine A is viable. Another promising application of Chinese club moss extract is in preventing organophosphate poisoning. These pesticides permanently suppress acetylcholine. This results in seizures due to a lack of interruption of the signals from nerves to muscles. The seizures can result in rapid death from uncontrollable seizures, or from permanent contraction of the diaphragm muscle that allows breathing. Although no human studies have yet been carried out, animals given Huperzine A prior to organophosphate exposure have survived without seizures. There are no doubts that Chinese club moss and the Huperzine A extracted from it are effective in preventing the suppression of acetylcholine, and in permitting the proper activity of this important neurotransmitter. It is finding an increasing number of potential uses beneficial to the human body, not the least of which would be a partial remedy for some of the effects of dementia and Alzheimer's disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1944) Holy Basil Extract
Date:
November 28, 2008 10:04 AM
It has been proposed that holy basil extract can help you cope with stress, and an investigation into the active components of the plant does indicate that there could be a scientific basis behind this use of it. This is in line with most traditional Ayurvedic medicines, whose benefits have been supported by modern scientific evidence. Holy basil, otherwise known as Tulsi or Tulasi in Sanskrit and Hindi, is correctly Ocimum tenuiflorum, an aromatic member of the Lamiaceae family just as the more common form of basil is (Ocimum basilicum). Holy basil is cultivated for several reasons, the major ones being for its essential oils, for culinary use, religious use and for its medicinal properties. It is grown right across South Asia. Thai holy basil is used in Thai cookery while other forms play an important role within some of the traditions of Hinduism and is found profusively around Hindu temples. Holy basil extract has been used for thousands of years for its healing and medicinal properties, and is mentioned in the ancient Ayurvedic text, the Charaka Samhita. It is written that it is used to balance a number of bodily processes and believed to be involved in promoting longevity. It is considered to be able to allow the body to adapt to stress and is also used to treat a large number of different medical conditions, from headaches to malaria and heart disease. Most modern medical studies, however, have been carried out on animals rather than human subjects, so definitive evidence is lacking, and while there is evidence that tulsi extract might be an effective antioxidant and help in the control of blood sugar, there is also compelling evidence that it might be able to counteract the effects of stress. First, let's have a look at the active ingredients of holy basil extract, and how they fit in with the beneficial medical properties claimed. One of the more important components of tulsi is eugenol, or 1-Hydroxy-2-methoxy-4-allylbenzene. Eugenol is a phenylpropanoid, also found in clove oil, and is a COX-2 inhibitor that is used in medicine as a local anesthetic. Two others are the triterpenes oleanolic and ursolic acids, which possess anti-viral and anti-inflammatory properties. The pentacyclic ursolic acid can inhibit the development of various forms of cancers through the inhibition of the STAT3 pathway that is responsible for several types of human cancer that have poor prognosis. Also present in holy basil extract is the polyphenol Rosmarinic acid which is a powerful antioxidant that is also present in herbs such as rosemary, oregano and thyme. Rosmarinic acid will also contribute to the anti-inflammatory properties of holy basil, and many of the antibacterial properties it is said to possess could be due to carvacrol, a terpene that damages bacterial cell membranes and inhibits the growth of a number of bacterial strains. Another component of Tulsi is the sesquiterpene B-caryophyllene, also contained in clove oil, and also possessing anti-inflammatory properties in mice. It is unknown whether or not these properties are transferred to humans, but the evidence of the use of the plant is that they are. Beta-caryophyllene is an FDA approved food additive, and as such, a dietary cannabinoid. Apegenin, also present in tulsi, is a flavanoid and another strong antioxidant and anti-inflammatory. With all of these ingredients that have proven health benefits, it is little wonder that holy basil is claimed to have the health benefits that it has. But what about its effects on blood sugar that it is said to control? It's probably not a coincidence that many other herbs that contain eugenol, such as cloves, are also claimed to have the same moderating effect on blood sugar levels. Not only that, but since diabetes is an inflammatory condition, it is not surprising that holy basil extract, that is rich in ant-inflammatories, should possess this property. The main theory is that many of the components of holy basil can help support the beta cell function of the pancreas, and so enhance the secretion of insulin. In one of the few controlled human tests, a group of 40 people with Type 2 diabetes stopped taking their normal medication seven days before the test. They were then given holy basil leaves for an initial period of 5 days. Half were then given 2.5g powder holy basil leaf and the other half a placebo for 4 weeks. The two groups then switched over for 4 weeks - the first being on the placebo, and the second taking the holy basil. With the first group, the average fasting glucose level dropped by 25.9%, from 234.5 mg/dl to 99.7. After switching to the placebo for 4 weeks it increased to 115.6 mg/dl (15.9% increase). The fasting blood glucose of the second group dropped from an average of 132.4 to 123.2 (6.9%), and then when on the holy basil leaf, dropped further to 97.2 mg/dl (21.1%). This demonstrates clearly that holy basil leaf reduces blood sugar significantly faster than fasting, and so is beneficial to Type 2 diabetics. Perhaps more such studies should be carried out to confirm these important results, which appear to conform to the theory that the components of the plant should have this type of effect on blood sugar levels. How about stress? Tulsi is said to particularly useful to people suffering from stress. The human stress response is an inflammatory cascade in which the immune system reacts by attempting to repair the stressed areas. If this response gets out of hand the stress can be exacerbated, and it is important that the stress response is carried put at an appropriate level. A COX-2 modulator can prevent the inflammatory cascade by inhibiting the COX-2 enzyme that causes it. Since eugenol is a COX-2 inhibitor, it can help to keep the body healthy and prevent the stress reaction. The antioxidant and anti-inflammatory properties of many of the components of holy basil extract can help to prevent the body being stressed by antioxidants and by today's environmental pollution and it also possesses antiviral and antibacterial properties to help reduce illness. It is also an adaptogen, which enhances your natural response to emotional stress and helps your body functional normally when stressed. Studies have indicated that holy basil extracts can reduce the levels of corticosterone, a hormone responsible for stress, and improve your mood and mental clarity. Longer term effects can include memory improvement and a reduction in the risk of age-related mental conditions. The active factors involved in the reduction of mental stress, and an increase in mental clarity, are the essential oils that tulsi contains, and their chemical components: particularly eugenol and caryophyllene. Studies have shown these to elevate the spirit and the mood, while the terpene acids, such as ursolic acid and oleanolic acid, can help to improve your body's response to stress. There are very few doubts of the effect of holy basil extract (or tulsi extract and leaf) in improving mood, mental clarity and reducing the effects of stress, or of its other extensive beneficial medical effects. More studies might be needed to prove them to the medical community, but even now people suffering from diabetes mellitus are benefiting from its moderating effect on blood sugar levels, and once again the application of Ayurvedic medicine is being proved as effective in the modern era as it was in the ancient world.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1941) Guarana Seed Extract
Date:
November 17, 2008 11:24 AM
Guarana comes from the Amazon basin, and has been used by the natives of the Amazon rain forest to treat conditions such as diarrhea, arthritis, fatigue and even to reduce hunger. It is, in fact, a climbing plant of the Sapondacaea family, although it is the fruit for which it best known. Each contains a single seed that contains around five times the amount of caffeine of a similarly sized coffee bean. An interesting piece of trivia is that the reason why such seeds are rich in caffeine is that the substance is poisonous to certain pathogens that would otherwise attack the berry. The same is - true of all seeds that contain caffeine: it is a means of self-defense. Obviously it is an effective defense since the berries appear to relatively immune to such common plant diseases. Guarana is named after the Guarani tribe of South America, and the language is spoken by many in the area around Paraguay, Bolivia and Brazil, and also parts of Argentina. In fact over 67% of Paraguayans speak the language. There is a myth that when child of the Guarana village was killed by an evil god, a more benevolent deity planted the child's left eye in the forest and the right eye in the village. The left eye gave rise to the wild form of the plant, and the right eye the cultivated form. This likely came about because of the appearance of the fruit when it is split open: it has the appearance of eyeballs. However, what is true is that Guaranis made tea from the seeds, and also a bread known as guarana bread by mashing the powder into a dough and shaping it into a cylindrical bread. It is dry roasted and milled to a fine powder, also known as Brazilian cocoa, but it has never quite managed to compete commercially against the coffee! However, it has its local adherents to whom it is a staple drink. However, back to the health benefits of the seed. They were recognized as early as the 17th century when Father Felip Betendorf introduced it into Western civilization, but over the centuries since then it has been found that even in spite of the caffeine content it has been demonstrated to have brain-boosting properties and able to increase tasks requiring mental attention. It is certainly known to be an energizer, and able to give a boost to your brain when you really need it. So why should this be, and how does it do this? The flavor is a bit like chocolate, hence its nickname of Brazilian cocoa, and has been approved by the FDA as a food additive. Extracts from the berry have been shown to possess strong antioxidant properties, and also act as bactericides and fungicide, few of which can be put down the caffeine content. In fact the seed has been proposed for use in the food industry as a natural antioxidant and preservative and as stated below, that is more acceptable to people than synthetic chemicals. This is probably in response to the fact that synthetic antioxidants are in decline whereas the natural antioxidants such as vitamins, C and E and the various tocopherols and carotenoids are increasing in prominence due to them being more readily accepted by the consumer than the synthetics such as butylHydroxytoluene(BHT). These antioxidants are commonly used as food preservatives, in that they slow down the oxidation of foodstuffs, and people are increasingly feeling that natural products are preferable for this application than synthetic. Guarana seeds have been found to be exceptionally high in proanthocyanadins with powerful antioxidant properties. They are fatal to free radicals and help to prevent cardiac disease and to improve cellular activity. They also display antimicrobial and antifungal activity. Chemically, they consist of up to 60% starch, pectins, saponins, proteins, and the aforementioned caffeine (3% - 5%). The guarana paste can contain up to 7% caffeine that can be dangerous to those with cardiac problems. Guarana also contains tannins at levels of up to 12%, including catechin and some proanthocyanadins. The astringency of these tannins represents a problem to their use in the beverage and food industry, although the substance is regarded as safe by the FDA. They have little if any nutritional value and can react with alkaloid and proteins to form unwanted complexes. Were it not for tannins guarana would be more acceptable to the food industry. However, it is for their energy-boosting properties that the guarana berries and seeds are most prized by many. The fact they it has been traditionally used as a stimulant and aphrodisiac indicates that there is something behind these claims. Studies on mice, hamsters and other animals have supported these effects. It has been found to posses the two desirable properties (to some) of stimulating the nervous system and curbing the appetite. Consequently, it is used in diet and weight loss pills, and also to maintain high energy levels. In fact weight loss pills are used by many people to maintain their energy levels while not eating. This is a definite bonus to those that want to lose weight, but dislike the lethargy that a strict diet can cause. There is a downside to that of course, and that is insomnia and an increased heartbeat, and also nervousness and feeling 'on edge'. Once people stop using guarana they suffer withdrawal symptoms such as nervousness, irritability and headaches. The upshot is that it is basically the high caffeine content of guarana that allows its use as a stimulant that can boost not only energy, but also reduce appetite and act as an effective weight loss supplement. However, used excessively it can lead to nervousness and while it is included as an ingredient in many foods and drinks, you should be careful when using it as an energizing supplement if you have any heart problems at all.
Otherwise, guarana is used to energize the body naturally, and is not only very commonly used for this purpose in South America, but also increasingly so in the USA and elsewhere with some very good results.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1936) Green Coffee Bean Extract
Date:
October 22, 2008 04:59 PM
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs. The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition. However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here. The Free Radical Theory of Aging Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them. Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging. Free radicals are generated in the body in four different ways: 1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a Hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher. 2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes. 3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting. 4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products. In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body. So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell. Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron. Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of Hydroxyl radicals. It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol. The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level. Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging. A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life. There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1922) Control Blood Sugar Naturally
Date:
October 01, 2008 12:10 PM
Your blood glucose level is generally controlled by insulin and glucagons, both of which are biosynthesized in the pancreas. Insulin works by making the glucose bioavailable to the mitochondria to convert into energy, while glucagon, the lesser known of this twosome, stabilizes the level of insulin and mobilizes it to do its job. There are two types of diabetes, known as Type I and Type II or A and B. Type I diabetes, also known as juvenile onset diabetes, is an autoimmune condition in which the immune system destroys Beta cells because they are recognized as being foreign. It is the Beta cells that generate insulin, and so the condition can be fatal. Patients with Type I diabetes must take insulin throughout their lives, and while potential cures are currently under investigation, none are yet available. Although insulin can be effective it does not guarantee survival, and a better form of treatment is required. Type II diabetes is by far the more common of the two, and is a form of resistance to insulin, where the body cells cannot use insulin properly. The pancreas initially reacts to this by producing more insulin in response to the increased blood glucose level, but through time it loses its ability to produce insulin as a reaction to an increase in blood sugar, even though this occurs as a result of digesting a meal. The exact causes of either type of diabetes are not known for sure, although the general mechanism by which they work is known. However, Type II diabetes is believed to be due to some form of interaction between genetics and environment, and it is known that the majority of Type II sufferers are obese and also over 40. The treatment for this type of diabetes is rarely insulin, but a controlled diet, control of your cholesterol level and blood pressure, exercise and specific medicines designed for sufferers of this form of diabetes. However, there are also natural supplements that can be used to control your blood sugar levels. Diabetes was the sixth leading cause of death of the USA in 1999, with 450,000 deaths, and by 2005 had reached about 300 million sufferers world wide. It is therefore a serious and widespread condition, though Type II is less serious than Type I. It is important to do what you can to control your diabetes, since after several years it can lead to problems with your nerves, eyes, kidneys and gums, and can also lead to heart disease. With diabetes you are at least twice as likely to have a stroke or heart problem as those without it, although you can reduce the risk of this by keeping your blood pressure under control, and the levels of fats in your blood to a minimum. Stopping smoking helps, and there are some natural treatments that can also help you control your diabetes. The most important means of control is to reduce your blood sugar levels. While there are natural products that will help you to do that, do not stop taking the medication prescribed by your doctor, but use these in addition to what you are already taking. Among specific substances that can help are: Chromium: chromium helps your body to use insulin properly. When taken in the form of chromium picolinate, it helps to replace chromium that diabetics appear to be short of. Human studies have indicated that chromium can decrease insulin levels and improve the metabolism of blood sugar in those with Type II diabetes. Some claim that chromium is harmful to health, but the general opinion is that it helps, though you should consult your doctor before using it. Cinnamon: If you take cinnamon daily, your blood sugar levels should gradually decrease. It appears to enable your cells to make better use of the insulin your blood, although there still discussion as to the mechanism by which this occurs and of the active ingredient in cinnamon that promotes it. Some claim it to be a flavonoid known as methylHydroxychalcone polymer, or MHCP. However, others claim it not to be MHCP, but polyphenol type-A polymer. Whichever it is, many people are finding cinnamon to be effective in reducing high levels of blood sugar to a more manageable level. Milk Thistle: It is known that antioxidants can help to control blood sugar, and the flavolignins in Silymarin marianum, an herbal extract available from milk thistle seeds, work in this manner. It is also good for protecting the liver from toxins. Although it is not clear how it is done, silymarin appears to help to control Type II diabetes possibly by way of liver digestion of sugars in the blood. The liver processed glucose and improving its function through the consumption of milk thistle could help reduce blood sugar as well. Mulberry: The Chinese make what is known as “sugar control herbal tea” from mulberry leaves, green tea and jasmine. Mulberry leaves contain adenine, pectin and choline, and also high levels of Vitamins A and B types. This tea is used by the Chinese to control blood sugar levels, which might occur through the antioxidant effect of the mulberry constituents. Salacia oblonga: This is an herb used in India and Sri Lanka that appears to cause a dramatic drop in the levels of insulin and sugar in the blood. It binds to enzymes in the intestine that break carbohydrates down into sugars, and so reduces the amount of sugar in your blood. That in turn reduces the amount of insulin released by the pancreas. Apple Cider Vinegar: There is evidence that apple cider vinegar can help to control your blood sugar levels if taken before a meal. Just two tablespoons appears sufficient to give a noticeable result. This is one of those home remedies that might be just anecdotal, but might also work, so is worth trying. Zinc: It has been discovered that diabetics suffer a deficiency in zinc. This mineral plays a part in the storage and production of insulin in your body, and a deficiency could cause an increase in your sugar level. Oysters, pecans, almonds, lamb and chicken are all good sources of zinc. Glyconutrient complexes: we know that diabetes is an autoimmune disease for type I individuals. Supporting a properly function immune system requires a good diet as well as a diet rich in Glyconutrients. The polysaccharides found in glyconutrient formulas can help the immune system communicate better with the body and just possibly correct some autoimmune diseases which attach our cells.
These are the natural supplements that people are taking to help control their blood sugar and diabetes. It is important that you take nothing that interferes with the medicines given to you by your physician, so you should let your doctor know of any natural supplement that you are using in addition to your prescription medicines. However, it is possible to control your blood sugar with natural supplements, and those mentioned above are just a few of the natural substances available that can help diabetics control their condition and so avoid the side effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1906) Garcinia Cambogia
Date:
August 28, 2008 09:33 AM
Garcinia Cambogia is found naturally in India and parts of Asia, and also on the Pacific coast of South and Central America all the way from Peru up to Mexico, and likes a humid forested environment. Also known as Brindall berries, garcinia is believed to act as an appetite suppressant and allows you to lose weight by diminishing your desire for food. The Malabar tamarind, as it is also known, is about the size of an orange resembling a small pumpkin, and an extract from the fruit and rind is used in several weight loss products. The health risks presented by synthetic diet pills render a natural product extremely attractive were it to be effective. So can Garcia curb your appetite? What is the scientific evidence for it, and what biochemical route would it take? Although tests on animals have been very positive, human results have been inconsistent. In some double blind tests using a placebo, weight loss was up to three times that of the control, but in others there was no apparent difference between those taking garcinia, and those given a placebo. However, doubts have been raised of the validity of some of the negative tests, so what does science tell us? The active ingredient in the cambogia extract is Hydroxycitric acid (HCA), which is a powerful inhibitor of ATP citrate lyase, an enzyme that catalyzes the reaction between citrate and Coenzyme A to Acetyl CoA and oxaloacetate. Since the acetyl CoA is necessary in the synthesis of fatty acids and lipogenesis (the conversion of glucose to fatty acids), then anything that inhibits the biosynthesis of acetyl CoA must help to reduce the amount of fat stored in your body. By inhibiting this reaction, that occurs outside the mitochondria so is not a direct part of the Citric Acid Cycle, HCA should theoretically suppress the formation of fats from carbohydrates, reduce food intake and thereby induce weight loss. But that is not the only mechanism. A study at Georgetown University in Washington found that after 8 weeks of taking the garcinia extract, there was a 5.4% reduction in body weight and body mass index, and a significant reduction in low density lipoproteins (LDL) and triglycerides with an associated rise in high density lipoproteins (HDL). This is good news for those suffering from high cholesterol levels, since the LDL lipoproteins are those that carry cholesterol to the major blood vessels, and which when oxidized by free radicals deposit fatty plaques on the artery walls. These plaques constrict the arteries and the resultant atherosclerosis can lead to cardiac problems and strokes. HDL lipoproteins carry cholesterol back to the liver for destruction, and is known popularly as ‘good cholesterol’. The studies also indicated modifications to certain indicators of the status of fat deposits in the body and of appetite modifiers in the brain. In this respect they found 38% decreases in serum leptin and increases in serotonin levels of 44%, and the excretion of fat metabolites in the urine increased from between 32% and 104%. These are significant findings, and further research has indicated that HCA helps to suppress appetite. Serum leptin is an indicator of the level of fat stores in the body, and as the leptin levels in the blood reduces, the hypothalamus is given an instruction to increase the appetite so as to increase the fat levels again. However, it is believed that HCA possesses leptin-like properties, and this signal is either not generated or is modulated. The increase in serotonin has the same effect. It is known that serotonin controls the appetite, although the exact mechanism has not yet been established. What is known is that serotonin activates certain neurons and melanocortin-4 receptors (MC4R) in the brain, that not only curb appetite but also block the effect of other neurons that would normally increase appetite by blocking the effect of MC4Rs. This is how the banned anti-obesity and serotonin inciting drug Fen-Phen operated, and it appears that the Hydroxycitric acid in garcinia cambogia extract acts in a similar, but safer, way. The problem with drugs such as Feb-Phen was that they created cardiac problems which could be dangerous to obese people whose hearts might have been weakened. However, now that the biological pathway by which serotonin controls weight is believed to be known, if not fully understood, the way is becoming clearer as to how safer weight loss pills, acting through appetite suppression, might be developed. It also provides a valid scientific explanation for the effect of garcinia cambogia extract which might in itself prove to be that safer way. The biochemistry supports the evidence of its effect on those wanting to lose weight, and also bolsters the claims that those tests and trials found to be negative were in some way flawed. Until the full chemical pathway is understood, the factors that can lead to flawed tests are unknown, although one could be the use of excessive fiber in some trials that could reduce the effect of the extract. One of the effects of HCA is to limit the ability of your body to convert carbohydrates into fat (the Acetyl CoA inhibition mentioned above). That, combined with suppression of your appetite and a higher rate of thermogenesis, prevents the body from storing excess carbohydrates as fat. Instead you will have increased energy levels, so you should exercise to use this up while taking garcinia extract. For this reason it is popular with athletes and bodybuilders seeking an energy source that has not yet been banned from sport. Although diet pills based on the same principle had side-effects and could make the user feel on edge, there are none known with garcinia. However, it is possible to reduce the absorption of some essential nutrients due to appetite suppression, so do not exceed the recommended dose. An excessive amount can also led to gastric discomfort, but none of these effects have been noted when the recommended doses have been adhered to.
However, if you are diabetic, pregnant or a nursing mother, you should consult with your physician or health professional before taking the extract. Garcinia Cambogia presents no specific risk to such people, and this warning should be given for all non-prescriptive treatments that your physician might be unaware of you taking.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1876) Denture Bonding Cream
Date:
August 04, 2008 12:56 PM
Denture creams, also referred to as adhesives can be a great tool for extra denture suction, which naturally leads to better denture grip. Secure Denture Bonding Cream is not only great for uppers; it is specially designed for lowers. As new technologies develop, denture creams have been prepared with cellulosic materials, such as sodium carboxymethyl cellulose, Hydroxyethylcellulose, and Hydroxypropylcellulose either alone or in combination with ethylene oxide homopolymers, acrylamide homopolymers and copolymers, or maleic anhydride derivatives to improve the adhesion properties of these creams, but there are some things you should be aware of. Most denture cream is slowly dissolved by your saliva, and studies have shown that it generally passes through your body without any ill side effects. Denture adhesive creams and similar compositions provide the desirable mechanical and aesthetic properties, at a minimum of cost, making these types of products inexpensive and effective for securing the dentures in your mouth. Being water soluble, these fixatives can dissolve, wash out, and result in the dentures slipping and sliding. Most denture creams are water-soluble and can be washed out by eating or drinking which may not be desirable at times. These creams act as a real adhesive which create a secure, strong, bond between the dentures and the gums. Look for a cream or adhesive that does not dissolve in water. These creams and adhesives are applied to the face of the denture or plate which is particularly adapted to contact and mold itself to the contour of a particular oral surface in the mouth. Multiple applications of the adhesive are not only inconvenient, but are usually impractical if not impossible depending on the cream or adhesive purchased. When the dentures become loose or pull away from the jaw, it will be necessary to apply more than one application of the denture adhesive per day in order to obtain and maintain sufficient adhesion throughout the day. Zinc is a very common ingredient in many over the counter and FDA approved products. Zinc is an essential mineral that is found in almost every cell in the body and in foods like red meat, poultry, whole grains and beans and is necessary for the maintenance of good health and nutrition. The potential for absorption of zinc through the gums is minimal but does happen. Zinc denture cream may adversely impact your health and create a copper deficiency in your body if left unchecked. If your mouth absorbs an excess of zinc, this overdose can lead to hypocupremia and neurologic diseases. Many studies have been performed on zinc over dose and neurological disease. All the studies of denture cream zinc overdose reached the following conclusion: Denture cream containing zinc and chronic excessive use may result in hyopcupremia. Tests for zinc levels in your blood can determine quickly whether you have a zinc overdose in your body. Action should be taken immediately against zinc pPoisoning if you or someone you care about has been experiencing symptoms such as numbness, tingling along nerve pathways and hypersensitivity and you use Poligrip or Fixodent, please consider being examined by your doctor. People who incur permanent damage from zinc poisoning due to use of denture creams may be eligible for compensation for loss, suffering and medical treatments.
In conclusion, good denture cream acts as an inexpensive, though temporary alternative to having your dentures relined. Most creams promise all-day hold however, with out personally testing each cream or adhesive it is likely that one may work for some but not all people. Denture adhesives also come with no warning make sure you read the label and avoid zinc products. However, ill-fitting dentures may impair your health- consult your dentist for periodic examinations and over all oral health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1851) Garcinia Cambogia
Date:
July 08, 2008 03:00 PM
Garcinia cambogia is a small tree bearing a small pumpkin-like fruit of the citrus family, and is steadily appearing in an increasing number of weight loss supplements. It is indigenous to parts of Africa and Asia, and the rind is commonly used in Indian cookery. Although the fruit is particularly sour to the taste, it is used in form of an extract of the rind and claimed to act as an appetite suppressant and also to increase the body’s capacity to metabolize fat. Although there are conflicting claims being made about its efficacy, or lack of it, research shows that it definitely has promise as an agent to prevent and fight obesity and its use is steadily increasing in this respect. The active ingredient is Hydroxy citric acid, otherwise known as HCA, contained in the form of the potassium and calcium salts of the acid in the aqueous extract of the garcinia cambogia rind. It forms up to 30% by weight of the rind. It is tasteless and odorless, and so far found to have no toxic effects on humans. Animal studies have also been generally favorable. HCA works in two specific ways both to reduce the desire to eat and to inhibit the storage of fat in the body. In each case, as with so many supplements that have an inhibitory effect on a physiological or psychological function or on a metabolic process, it involves an interaction with enzymes. Citrate lysase is an enzyme in the body that helps to prevent lipogenesis and instead promotes the conversion of carbohydrates into fat. When this enzyme is inhibited from carrying out its intended part in the body’s metabolism, the process of carbohydrate oxidation is boosted, or, in other words, the excess carbohydrate is burned off, or changed into energy. More fats could also be expelled unchanged from the body, but irrespective of that the end result is that less carbohydrate tends to be converted to fat. Garcinia cambogia, however, has not been found to reduce the body’s uptake of essential fatty acids which are necessary for health. Had this occurred, you would feel a raging hunger as opposed to the appetite suppressing properties the extract is claimed to have. The oxidation of carbohydrates can also lead to thermogenesis, or the boosting of the metabolism by increasing your body temperature. An increase in the metabolic rate helps weight reduction through an increased calorie demand while your body is at rest. However, that is not the only way in which the HCA extract works to help reduce your weight, or at least help to maintain it at a healthy level. Let’s return to its specific appetite suppression properties. Serotonin (5-Hydroxytryptamine) is a neuroreceptor found in the central nervous system. It has many regulatory effects on the body, one of which is appetite. Although it is by no means the only chemical in the body that has an effect on the appetite, serotonin is a significant factor. As you get hungry, serotonin is released in the hypothalamus, an area of the brain that regulates sleep and eating. The release of serotonin increases when you see and or smell food. It is the agent that starts canine salivation, and a ravenous hunger in those that have no immediate access to food. It also causes you to snack, and, as you eat, the serotonin level in the hypothalamus continues to increase until it reaches a point where it provides the hypothalamus with a feeling of repletion or satisfaction. You then stop eating. So the more serotonin is produced, the quicker you stop feeling hungry. Garcinia cambogia extract has the effect of stimulating the emission of serotonin into the hypothalamus, and so suppresses your hunger quicker. You don’t stop eating altogether, but attain that feeling of satisfaction much quicker and so tend to eat less with each meal. This can not only help you maintain your weight at a healthy level, but also to reduce weight in the obese. Although the extract can work through each of these mechanisms, it does not have such a significant effect on a very fatty diet. It can help if you switch to a relatively healthy diet, lower in fats, but the effect might not be strong enough to compensate for a poor diet in terms of fat content. Studies have indicated an anti-oxidant activity that likely comes from the xanthones and xanthone derivatives that are also contained in the fruit. In fact there are other recorded uses of garcinia cambogia, and it has been used in traditional Indian medicine to treat fevers, dysentery, open wounds, ulcers and tumors. According to a study carried out for the National Cancer Institute there is no documented toxicity effects on humans, and there is no regulation regarding the use of garcinia cambogia. It has not been evaluated by the FDA. However, there are contra-indications in the case of pregnant and lactating women, more as a safety measure than for any particularly known risk. Alzheimer patients should avoid taking HCA since there is a possibility of it promoting the synthesis of acetylcholine in the brain, and its glycemic action renders it unsuitable for diabetics. Conversely, this same action is a positive benefit by reducing the craving of healthy adults for sweet foods. However, HCA is frequently taken in combination with chromium due to the latter’s positive effect on the regulation of blood sugar levels. Nevertheless, diabetics should avoid any supplement containing chromium without professional medical advice. The supplement should be standardized on the HCA content, and an average dose is around 500 mg – 1000 mg of 50% extract a day. However, this varies, and the most important aspect of such extracts is that when changing brands; be sure to compare the strength of the relative extracts and change your dosage accordingly.
Although the benefits of garcinia cambogia to those seeking to lose weight are debated, there is ample evidence to suggest that a regular intake of the extract is beneficial – and not only with respect to the maintenance of healthy weight.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1833) Copper
Date:
May 15, 2008 01:21 PM
Copper is an essential trace mineral necessary for life, and it is necessary for the proper function of certain enzymes that allow certain biochemical functions of the body to take place. Without copper neither plant nor animal life would be possible. Dietary sources include nuts, grains, seeds, beans and other vegetable protein sources. Although it is also obtained from animal sources, these tend to be rich in zinc, and for reasons that will be discussed shortly, the presence of zinc can deplete copper absorption. Other common sources are copper cooking utensils and drinking water from copper pipes. After digestion, copper is absorbed into the body through the stomach and the small intestine. It is also possible for copper to be absorbed through the skin from copper bracelets. Once absorbed, copper is bound to albumin and taken by the blood to the liver, where it is bound to a plasma protein known as ceruloplasmin. Among the enzymes with which copper is associated as a ‘helper’ are Cytochrome C oxidase, used in the conversion of glucose to energy, Dopamine Hydroxylase, an essential component in the biochemical production of adrenaline, and superoxidase dismutase, that protects against the oxidative damage of cell tissue. Of particular benefit are its anti-inflammatory and antioxidant properties, and its role in energy production. Because of its antioxidant effect, copper could well play a very important role in protecting against atherosclerosis, and cardiovascular disease, the ravaging effects of free radicals on body cells and also certain forms of cancer. Copper is also important in electron transport, and is responsible for the blue coloration of the blood of most molluscs and many arthropods. This is because rather than hemoglobin, these animals use the copper-based hemocyanin for oxygen transport in the blood. Rather than the iron-containing hemoglobin making the blood of these creatures red as it is with mammals, theirs is blue due to the hemocyanin. Copper salts are generally green and blue, as are the blue copper proteins plastocyanin and azurin. So how is copper used by the body? It is, after all, fairly toxic, as little as 30 grams being fatal to humans, bringing on similar symptoms to those of arsenic poisoning. It is in fact the reason for its toxicity that also renders it so useful to the body. The toxicity is largely due to the ability of copper to accept and donate electrons as it changes between oxidation states. This results in the generation of very reactive radicals that can cause severe oxidative stress. The complete reason for its toxicity has yet to be determined, but the stress caused to body cells by free radical oxidation is a very serious condition. It is this rapid change in its oxidation state that is valuable to the enzymes with which it is associated. The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase. In doing so the copper is converted to the monovalent state. It also helps to aid in the production of the strong antioxidant Superoxide dismutase (SOD). What this enzyme does is to catalyze the formation of oxygen and hydrogen peroxide by the dismutation of superoxide, a negative ion consisting of two oxygen atoms and a free electron, and hence a very powerful free radical. Dismutation is the simultaneous oxidation and reduction of the species, rendering the free radical relatively harmless. This type of action on free radicals is a very powerful one, and essential in the body’s fight against such free radical species that are so dangerous to animal cells. SOD exists in more than one form, and can also contain zinc, manganese and nickel in addition to copper. The internal fluid (cytosol) of practically all eukaryotic cells (cells containing a nucleus) contain a form of Superoxide dismutase dependent on copper and zinc, while most mitochondria contain an SOD with manganese. Another of the important uses that your body can find for copper lies in the production of hemoglobin. This is because copper is needed for the storage and release of iron to produce hemoglobin, the protein in red blood cells. It is believed that ceruloplasmin is involved in the catalytic formation of ferric iron by the oxidation of ferrous iron, so allowing the iron to be attached to a protein that transfers it round the body to enable its use in the biosynthesis of various ferrous compounds, especially of hemoglobin. Copper bracelets are commonly worn by arthritis sufferers, and there is a scientific explanation for that. As previously inferred, it is believed to be possible to absorb copper through the skin and copper is known to be involved in the formation of collagen and is a commonly used treatment for arthritis and osteoporosis. Part of its effect on arthritis is likely due to the antioxidant effect of the SOD that helps to reduce the inflammation at arthritis sites. Although a deficiency in copper can lead to serious health problems, an excess is also harmful. Potential conditions include neurological problems, liver damage and bone abnormalities, although deficiency is far more common because of the competition between copper and zinc. Zinc is a copper antagonist, as is iron and manganese, and copper imbalances can be moderated by the use of these as supplements. The symptoms of a copper deficiency include fatigue, hair loss, stunted growth, anorexia and a host of other conditions. Luckily, however, a deficiency is rare and most people receive a sufficient amount of copper in their diet. Supplements are available to ensure an adequate intake. There is still much to be learned about the interaction between copper and enzymes, and there is also a great deal still to be learned of its role in human metabolism and biochemistry than is currently known. However, sufficient is known already for us to be certain that copper is a very important trace element and that we should be certain that our intake is sufficient, given that zinc iron and manganese compete to prevent copper being absorbed by the body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1790) Grapefruit Seed Extract
Date:
May 06, 2008 05:14 PM
Grapefruit seed extract is regarded as being natural antibiotic that is effective against a broad range of bacterial infections. It has also been used to treat parasitic infections and a range of viral infections as well as having found uses for a wide variety of medical conditions. So what is it about grapefruit seed that is so special? Most people are acquainted with grapefruit, which as a member of the citrus family of fruits, and not to be confused with grapes which are a totally different type of plant. Grape seed extract is also a useful natural medication, but used for totally different conditions. Because of its efficacy against parasitic and viral infections, grapefruit seed extract is very useful in treating various forms of food poisoning. But, how was this remarkable property of the simple grapefruit seed noticed? The answer to that depends very much upon what version of the story of Einstein Laureate physicist and immunologist Dr. Jacob Harich you believe. Dr. Harich was not only a scientist but a hobby gardener in Florida, and the two versions of his story tell either that he decided to investigate why grapefruit seeds tasted so bitter, or why the grapefruit seeds in his compost heap failed to compost, or rot. Whichever story is correct, and perhaps both are, the result was the discovery that grapefruit seeds appeared to be a very effective antibiotic. In fact it has been shown to be effective against over 800 strains of bacteria and viruses and also effective against many fungi that lead to illness in humans. Because of this it is used in cased of food poisoning that involve bacterial infection of the gastrointestinal tract. In fact during the latter part of the 1980s, grapefruit seed extract was tested against a number of known antibiotics and found to be as effective as any of them. Similar results obtained in a number of tests in the USA and elsewhere in the world, and it appears that it is an excellent treatment for the symptoms of food poisoning. Not only that, but it has been found effective in the treatment of some immunodeficiency diseases, presumably because its antimicrobial properties does much of the work that the immune system would normally do, and so relieves it of much of its hard work. This allows the immune system to concentrate on conditions which are exacerbated by deficiencies in its operation. Bifidobacteria and Loactobacilli are bacteria that are beneficial to the digestive system. The measure of a good broad spectrum antibiotic is that it does not affect the beneficial bacteria, and grapefruit seed extract has no effect on the former and only a mildly inhibiting effect on the latter. It is also non toxic to humans, which is another measure of a good antibiotic. You would have to drink about two pints of the extract, around 4000 time the normal dose, for the treatment to be potentially fatal. Among the many uses of the extract are not only in controlling gastrointestinal infections, but also general fungal conditions of the skin, vaginal infections and yeast infections, and also colds and sore throats. It is also believed to support the immune system, not only by its antimicrobial properties but through its effect on intestinal health upon which much of our immune system is dependent. It can also protect patients with symptoms of AIDs and other immunodeficiency conditions from infection. Its effect on yeast infections around the nether regions of small children has been documented, and it has also been found to be very safe to young children. In fact many mothers have it as a permanent addition to their medicine cabinet. It is not that long ago when doctors believed all diseases to be due to bacteria or viruses. It is now becoming clear that a large proportion is actually due to fungal infections and parasites. Many conditions such as allergies, circulatory disease and some forms of arthritis have been shown to be due to fungal infections that weaken the immune system. Grapefruit seed extract has been found to be effective in treating many types of fungal disease. In using the extract in this way, and to treat bacterial infections, it is best to start with a low dose and gradually increase it. This is because when fungi and bacteria are destroyed they release toxins, and too high a dose could result in too much toxin being produced for your body to handle. If you take it gradually you will get the same result, but without the risk of the nausea and diarrhea which the toxins can cause. Despite all of these benefits, grapefruit extract has not been given the credit it deserves, and much research has still to be done to establish the constituents of the seed that confer these properties. Among these are known to be proanthocyanadins, a class of flavanols with strong antioxidant properties, and a diphenol Hydroxybenzene complex that destroys bacteria through the cytoplasmic membrane to prevent the uptake of amino acids and cause leakage of the cell contents. Other active components are Vitamins C and E, tocopherols, limonoids and sterols, in addition to a number of important minerals. However, there is still much work to be done, although the extract will continue to be used by many devotees for the treatment, not only of food poisoning symptoms, but also of conditions such as acne, athlete’s foot, gingivitis, cold sores, sinusitis and parasitic infections. It appears to be practically a cure-all. There appear to be no drug interactions, although some medications do react with grapefruit juice, such as some treatments for high blood pressure. If your treatment advises you not to take grapefruit juice, then do not take grapefruit seed extract. Another factor to be aware of is that since the extract is an effective bactericide, then it could deplete the digestive tract of friendly bacteria essential for digestion. You are advised, therefore, to take a supplement of acidophilus, which is easily taken in the form of yoghurt type drinks specifically formulated or dietary supplement for the purpose.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1783) Third- The Science (Putting It All Together) Boswellia & Inflammation
Date:
April 03, 2008 12:44 PM
Frankincense has traditionally been used in Ayurvedic medicine for centuries, and is even mentioned in the Bible. The trunk exudes a resin containing mono- and sesquiterpenes that possess powerful anti-inflammatory properties. They are also well known antiseptics and astringents, and support the immune and respiratory systems. These terpenes are commonly referred to as boswellian acids, and consist of a carboxylated pentacyclic triterpene with at least one more functional group. Both the alpha and beta acid have a Hydroxyl (-OH) grouping, and there are also the acetyl (CH3CO-) equivalents with an acetyl group replacing the OH. There are other so-called-boswellian acids, and it is believed that they all play a part in the anti-inflammatory properties of the resin. The acetyl derivatives are thought to be involved in the death of some cancer cells, particularly those involve in brain and colon tumors, and also leukemia. The way in which they achieve this appears to be a programmed progression that ends with the dying out of the cells rather than a violently destructive mechanism, which lends credence to the Ayurvedic belief that the treatment is a natural one designed by nature. The anti-inflammatory properties of the acetyl triterpenes are due to their effect on leukotrienes that sustain the inflammatory reactions of many allergic reactions and also of asthma. They appear to inhibit the enzyme elastase in leukocytes; this is a crucial enzyme in the production of the chemicals that promote inflammation. It has been established that the inflammatory response of the immune system is due to the action of specific enzymes, so it stands to reason that if you can inhibit these enzymes, then you will also inhibit the immune response to specific initiators and so reduce the pain involved. Bosellian acid in the form of triterpenes appears to contain these inhibitors, and this would appear to explain its effectiveness. Pinene and phellandrene are among the terpenes isolated from Boswellia. A standardised dose of 60% - 65% of Bosellian acids is generally used, so if you are purchasing Boswellia this is what you should be looking for. Keep in mind that it is intended to treat inflammation, ands that inflammation is an indicator that something with your body is not quite right. Therefore, while inflammation is painful, and Boswellia may help, you should also treat the cause of the inflammation by treating the immune system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1741) Astaxanthin, a Member of the Carotenoid Family, is a Powerful Antioxidant
Date:
January 31, 2008 09:00 AM
Astaxanthin is a member of the carotenoid family responsible for the red color of many types of algae. Being a carotenoid, it is a powerful antioxidant and free radical scavenger as well as support proper eye function. However, such a bland statement belies the true worth of astaxanthin in its fight against free radicals. It is of particular benefit in its ability to absorb the high energy of singlet oxygen, releasing it as heat, and returning the singlet oxygen to its ground neutralized state. Singlet oxygen is a particularly harmful and reactive oxygen species of free radical that is formed in the body as part of our normal metabolism, and that contains a high level of free energy that can be used to oxidize and destroy the cells of your body. In achieving this, astaxanthin is regarded as one of the most potent plant derived antioxidants known, being up to ten times more active than beta carotene, Lutein or its cousin canthaxanthin. So why are antioxidants so valuable to our biochemistry and what would happen if they did not exist? Free radicals are thieves that use your body as their operating ground. They operate by stealing an electron from a molecule that comprises part of you, and in some cases when this occurs the cell from which the electron is removed is destroyed. Generally electrons go around in pairs, but occasionally an electron pair can lose one of the electrons during a chemical reaction. Many such reactions occur naturally inside the body, especially during the production of energy from blood sugars in the mitochondria, and such a molecule containing a single unpaired electron is called a free radical. Free radicals are also generated by the reactive components of many pollutants such as traffic fumes and cigarette smoke, tars and pesticides, and also by the effect of UV radiation in sunlight. The only purpose of a free radical is to steal an electron from the first source it can find. Such reactions occur very rapidly after the free radical has been generated, and if this electron belongs to another body cell, then the cell is destroyed leading to effects such as premature aging or even cancers. Free radical oxidation of the LDL lipids that carry cholesterol around the blood causes the deposition of fatty plaques inside arterial walls that eventually become constricted or even blocked, leading to heart disease or strokes. That is why antioxidants that destroy these free radicals are so prized, and the more of them that there are in your body then the less affect the free radicals will have on you. You will retain your youthful looks longer, and will be less liable to suffer from heart disease, cancers, circulation problems and conditions such as diabetes. Many abnormal conditions can be laid at the door of free radicals. The stronger the free radical, the more harm it can do to you and a strong antioxidant such as astaxanthin is a very powerful weapon in your armory against them. Astaxanthin is a member of the oxygenated xanthophylls, and its high level of antioxidant power likely comes from the ketonic and Hydroxyl functional groups of the ionone ring structure. It is more polar than most carotenoids, and this is a likely reason for its ability to span the cell membrane layers, with the active groups close to the hydrophilic-hydrophobic interface. They are thus more readily available at the sites where most free radicals tend to be found and provide immediate protection to the cell membrane and also to the intracellular mitochondrial membrane. Many antioxidants destroy free radicals by donating an electron, and become oxidized themselves. Astaxanthin, however, does not do this, but instead adds the free radicals to its long double bonded chain hence avoiding oxidation and rendering it much more powerful than normal antioxidants. It is unusual among antioxidants in that it is also able to cross the blood-brain barrier, and so reduces oxidative stress that can cause neurological disorders in general, and also problems with eyesight. It can also attach itself to lipoproteins to enable it to be carried throughout the bloodstream, being available anywhere that free radicals are generated. The carotenoid is also active against active oxygen species that are responsible for inflammation. Another property is its ability to neutralize the oxygenated free radicals formed by the photo-oxidation properties of UVA and UVB radiation. Included in these are the previously mentioned highly reactive singlet oxygen and also triplet oxygen that astaxanthin is able to neutralize without becoming oxidized. In fact reactive oxygen species in general can cause oxidative stress, and they have been thought responsible for many forms of disease and health conditions, and the powerful effect of astaxanthin in targeting many of these has led it to be regarded as highly beneficial to the immune system and to health in general. Another benefit is the ability of the substance to help prevent the oxidation of high density lipoproteins (HDL) that are responsible for carrying cholesterol in the blood back to the liver for destruction. Free radical oxidation of HDL impairs its ability to transport cholesterol, and so decreasing the level of such free radical oxidation will by definition increase the quantity of good HDL available, and hence reduce the concentration of cholesterol in the blood. Studies have proved this to be the case, and astaxanthin supplements are very beneficial to those suffering from high blood cholesterol levels, and helps protect them from heart disease and strokes. The substance is naturally available from a wide range of marine sources, such as lobsters (where it was first discovered), shrimp, salmon, trout and in a wide variety of red and green algae. The substance is also used as a red pigment. Carotenoids are essential, meaning that they are not produced in the human body and can only be obtained in our diets. For that reason, the most convenient way to take it, apart from continually eating shrimp and lobster, is as a supplement. Astaxanthin is available either as a powerful antioxidant in its own right, or in combination with other substances with which it acts to provide a very strong deterrent to any free radicals that think they can freely roam your body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1711) Natural Bar Soaps for the Kitchen and Bathroom
Date:
January 23, 2008 11:59 AM
Good natural bar soaps that contain only substances that are good for your skin are available, although most people pay little attention to them. Many people might be unaware of the fact but the skin is the largest organ of the body. As such, the skin needs taken care of just as much as any other major organ, yet few people pay much attention to what they bring into contact with it. Although a lot of money is spent on body products, do you really know what your skin needs for optimum health and what substances can do it harm? Your skin carries out many functions other than keeping the bits inside that should be kept inside. It is a natural thermostat, containing the sweat glands that dampens it and allows evaporation to cool you down. It contains hairs and subcutaneous fat, both of which help you to remain warm when the external temperature is low. Your skin is designed to remain supple, and so allow free movement of the various parts of your body. It is an ideal waterproof covering for your body that also protects you from infection. Although infection can set in if the skin is ruptured through cuts or grazes, the skin itself rarely suffers from surface infections when related to the number of infectious agents it is constantly in contact with. The health of your skin is very important, especially in view of the fact that it regularly comes into contact with some very hazardous substances. What may not have occurred to you is that one of the many functions of your skin is to eliminate some of the body’s waste products. It does this when you sweat and the toxins that are emitted can harm it. Although not often infected, it does suffer from complaints such as psoriasis, eczema and acne that are not primarily caused by bacterial agents or viruses, and hence not true infections. These conditions, however, are caused largely through the emission of toxic agents through the sweat glands. Acne for instance is caused by excessive emission of sebum that combines with dead skin cells to form acne which can also become infected with bacteria. Psoriasis is the excessive formation of skin cells at too rapid a rate, the true causes of which are as yet unknown. Skin cells can become cancerous due to excessive exposure to sunlight or ultra violet radiation, and skin cancer is the most common type of cancer that your doctor is liable to come across. If you suffer from any specific skin condition, such as acne, or even dry skin that can be caused through excessive exposure to degreasing agents or dry winds, then your skin will need special care. The soap you use is very important in the way you care for your skin, and many people will use soaps that contain many ingredients that they cannot pronounce let alone understand. Your skin needs cleansed regularly since it comes into contact with many dangerous and toxic substances. Apart from the everyday pollution of traffic fumes and factory emissions, there are also the substances that contaminate your skin at work and at home. At home specially, domestic cleaners can be very harsh on your skin, consisting of substances that are intended to clean away greases and oils, the very types of substance that protect your skin from the elements. When you clean your oven or your sink without gloves, you also clean off the protective oily layer on your skin and leave it open to bacterial attack. Your skin can also become sensitized to many substances, so that whenever it comes into contact with them it promotes an allergic reaction that can cause irritations so severe that your life can become very miserable. Many people are allergic to various types of soap or detergent because they have become sensitized to them, and are unable to use that type of cleanser after sensitization. Many soaps contain active ingredients that are intended to carry out specific functions. Thus, some contain antibacterial agents to inhibit the growth of specific types of bacteria on your skin, while others contain detergents to improve their cleaning power. However, some detergents can be very harsh on your skin, and try to avoid bar soaps containing PEG-6 methyl ether or butylated Hydroxytoluene (BHT). These can be harmful to your skin. There are others, and if your skin is sensitive try to avoid soaps containing animal products or petroleum derivatives. Take tetrasodium EDTA, which is present in common bar soaps. It enhances the penetration of substances through your skin, which means that it can also enhance the penetration of the lees welcome ingredients in the soap as well as the moisturizers. Substances as sodium etidronate that is a synthetic preservative that might cause irritation to your skin and mucus membranes. There are several other synthetic detergents that are ingredients in bar soaps, and many kitchen soaps contain the same ingredients as personal or bathroom soaps, the difference between them being only in their moisturizer and perfume content. Other ingredients than can cause potential problems are limonene, linalool and camphor, all of which can give rise to unwelcome conditions such as irritation or respiratory problems. The first two of these are common in bar soaps, as are benzaldehyde and benzyl alcohol which are irritants. Alpha-pinene, found in some bar soaps, is a sensitizer than can damage your immune system. Unless you know what a specific ingredient is, don’t use the soap. Instead you should use pure natural bar soaps containing antioxidants that are good for your skin. A pure soap should contain the fat or oil that it is made from, good examples being coconut or palm oils, water, a water softener to enable the soap to cleanse the skin properly, an example being one of the penetrates, a moisturizer such as glycerine or lanolin and possibly a perfume derived from natural sources. Salt is also frequently used, and is a good bactericide. Wherever possibly, you should choose a natural soap containing antioxidants. Citrus soaps, for example, contain vitamin C although many soaps contain antioxidants such as beta carotenes, vitamin A and vitamin E. Since soap consists of both oils and water, you can have both oil and water soluble antioxidants in your soap. The antioxidants help to protect your skin from the ravages of pollution and the effects of the sun’s rays, both of which generate free radicals that can accelerate the aging and wrinkling of your skin. A good antioxidant, moisturizer and wetting agent in your bar soap will help to protect your skin from the effects of atmospheric pollutants, the drying effect of the sun and wind and also effectively cleanse the skin surface and pores of everyday dirt. If this is associated with an absence of synthetic chemicals that can cause irritation then you will be giving your skin the best protection that you can. This is true of soaps intended either for the kitchen or the bathroom.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1705) Green Coffee For Protection Against Oxidative Stress
Date:
November 17, 2007 11:46 AM
It is recorded that coffee drinking originated in Ethiopia in North East Africa, from where Arab traders introduced the plant to the Middle East. From there it moved to Turkey in the 15th century, where it was highly prized as a daily beverage due its invigorating properties. It is also believed that the infamous Captain John Smith introduced the plant to Virginia. The Brazilian coffee trade was due largely to the introduction of the bean to that country by the French in 1727, and the Boston Tea Party of 1773 rendered it the only non-alcoholic drink worth consuming by the patriots of 18th century America. Now over 50% of Americans drink coffee daily, although this seems a somewhat conservative estimate, and the tea houses of England have largely been replaced by coffee shops and the ubiquitous Starbucks. So much for the history of a beverage that has been prized for its stimulant properties, but recent research has established that not only is coffee a stimulating drink, but that it is a strong antioxidant due to its polyphenol content. However, not all forms of coffee have this property, only the green coffee bean before it has been roasted. Polyphenols are very powerful antioxidants that scavenge the free radicals that destroy body cells, and not only accelerate aging but also threaten the health of your cardiovascular system and the health of other major organs. Free radicals are compounds with a spare electron. Normally the electrons in all stable molecules come in pairs, and any free electron without a partner is like a lovelorn bachelor. It will seek a mate, and take it from wherever it can find one. Usually it secures its partner by stealing an electron from one of our body cells. This can totally destroy the cell, as it might anybody who has its partner stolen, and cell destruction is not a good thing. It is the destruction of body cells that promotes the appearance that aging brings: the wrinkles and the loss of energy that is generated by healthy cellular activity. Antioxidants destroy these free radicals, and come in a number of different guises. Vitamins A, C and E are all powerful antioxidants, as are many of the compounds that are essential to our biochemistry such as beta carotene and polyphenols. These polyphenols are found in practically all plants to a greater or lesser degree, and another rich source is grapes, and those found in green coffee beans are what are known as Hydroxycinnamic acids the most abundant of which is caffeic acid. Another is chlorogenic acid, and together they form a very potent team in preventing the oxidation by free radicals of LDL (low density lipoprotein). Low density lipoproteins are those that carry cholesterol from the liver to areas of the body that need first aid due to damage, such the arterial walls. However, this can be attacked by free radicals and oxidized which results in the deposition of excess cholesterol that can build up till it eventually constricts, and sometimes completely blocks, the major cardiac arteries. This is a serious condition known as atherosclerosis that can eventually lead to cardiac disease and arrest or to strokes if the artery is in the brain. Not only do chlorogenic and caffeic acid help to prevent this from occurring, but they also help to prevent the cellular degeneration caused by the free radicals. They must be extracted from the green coffee bean because roasting or heating in any way, including brewing, destroys them. In fact, brewed coffee contains some potentially harmful substances called diterpenes that some believe can increase your chances of coronary disease by up to fifth if you drink coffee regularly over your lifetime. It is also believed that green coffee extract can reduce the risk of diabetes due to its effect on your blood glucose levels. Evidence is coming to light that some polyphenols, including chlorogenic acid, might have inhibiting properties on the activity of glucose-6-phosphate, otherwise known as Robison Ester, which is involved in the metabolism of blood glucose and which is affected by diabetes which reduces its concentration. Chlorogenic acid is though to be able to redress this imbalance and not only reduce blood glucose levels, but increase the glycogen stored in the liver as an emergency energy source for the body. Green coffee bean extract also possesses other beneficial properties, not the least of which is its effect in increasing the metabolism of fats in relation to carbohydrates. This assists in weight loss and also increases stamina. The decrease in the risk of diabetes of up to 50% in men, and slightly less in women, could be due to a combination of the regulation of glucose-6-phosphate and the regulation of blood glucose levels and glucose and weight management in general. The vast majority of diabetes patients are overweight. In animal studies, the presence of chlorogenic acid appears to reduce the hyperglycemic peak that arises through the action of glucagon, a hormone used to counter hypoglycemia. The fact that chlorogenic acid reduced this sugar peak indicates its potential use in reducing abnormally high blood glucose levels. Another effect of this was an increase in the animal’s glycogen level and in the level of glucose-6-phosphate in the liver. This indicates a reduction in glycogenolysis, by which glycogen is ultimately converted to glucose-6-phosphate and glucose, thus increasing the blood glucose levels and also of gluconeogenesis which is the production of glucose from carbohydrates and some glucogenic amino acids. In other words, green coffee bean extract can help to regulate blood glucose levels by preventing the liver from producing glucose from glycogen and carbohydrates. However, the biochemistry apart, it must be stressed that these benefits are not obtained by drinking coffee, and it has to be repeated that the active agents in providing them are destroyed by the roasting and brewing processes. It is only the green coffee beans that can be used for protection of oxidative stress of human body cells and the gradual degradation into premature aging and many other related conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1635) Prevent Disease With Discount Vitamins
Date:
October 24, 2007 09:33 AM
You can prevent disease with discount vitamin just as easy as with those you pay top dollar for on the High Street. Vitamins are vitamins, and they do not lose quality for price as long as you know what to look for and stick with name brands. They are the most purchased supplement in the western world, and there are ways of getting them for less than the normal price. First, though, a definition of what a vitamin is since an astounding number of people have no idea of what actually constitutes a vitamin even though they can recite all the letters. In fact, a vitamin is a molecule, obtained from an organic animal or vegetable source that is essential for life. Without it there can be no animal life and vitamins generally catalyze or act as coenzymes in the biochemistry that makes up all of the chemical reactions of the body. A catalyst allows a reaction to occur without changing itself, and a coenzyme allows enzymes to do their jobs. Let’s have a look at one or two vitamins to provide examples of these statements. In bygone days when sailors used sail to cross the oceans in open boats powered only by sail and oar, a trip that takes us a week in a cruise liner these days could take sailors several months. It was not only the fact that they relied on favorable winds, but also that they did not always know where they were going, and were frequently unable to store up for a whole voyage. They depended on landing at islands on the way to replenish supplies. Disease due to lack of nutrition was common and one of these was scurvy. This condition is not strictly a disease and is due to a lack of vitamin C, or ascorbic acid. In fact the name ‘ascorbic’ comes from the Latin for ‘without scurvy’. The symptoms are liverish spots over the body, spongy gums that cause the teeth to fall out and bleeding from the mucus membranes. Healed scars will open up, and cured and knitted bone fractures will separate. Ultimately it causes death. The first person is used since scurvy still exists. It is due to a breakdown in the synthesis of collagen which heals scars, keeps joints held together, and forms the outside part of cells, and also some inner cell structures. Collagen synthesis is dependent on the amino acids proline and lysine that are Hydroxylated by the enzymes lysyl and prolyl Hydroxylase. The problem is that these enzymes need ascorbic acid (vitamin C) to do their work. Without it, collagen cannot be made. Although the chemistry was unknown, early sailors soon found that citrus fruits such as lemons and limes prevented this horrible condition. The English used to stock up their ships with fresh limes at any port of call that had them, and this is why the English are frequently referred to a ‘Limeys’. It got them a nickname, but it saved their lives. Scurvy is now rare, but it is not a disease as such that can be eradicated. It occurs now and again in teenagers with poor diets that do not include fresh fruit and vegetables. Vitamin C supplements are now available, and it is one of the most common of the discount vitamins on the market. The same is true of vitamin A that is essential for good eyesight. It has many other uses, as has vitamin C, but without it we could not survive. Without it we will eventually become blind, although the first symptom is night blindness. However, an excess can lead to hypovitaminosis A, a condition common in the developed world. Its absence can kill us, and vitamin A deficiency is one of the more common conditions of the developing world. Vitamins are contrary creatures, and can do us harm as well as good. How about vitamin D, the sunlight vitamin? We don’t think of it, yet it is responsible for the strength of your skeleton and the regulation of calcium and phosphorus levels in the blood. Without it our bones become soft, our children get rickets and we eventually die – frequently through cancer. 1,25-diHydroxycholecalciferol is the chemical name for calcitriol, which is the form of vitamin D found in the body, known as vitamin D3. This has been found to kill some cancer cells in the laboratory, and it is thought that supplements of vitamin D might help to prevent some types of cancer. The reults of a four year cancer study were released in June, 2007, that showed a reduction of 60% in cancers where patients were given a aupplement of 1100 inernational units daily. This rose to 77% where the cancers had been diagnosed in their first year. The effect of vitamin D was emphasized by the reults of a study of more than 4 million cancer patients that showed a marked difference in the risk of cancer according to whether they lived in sunny or less sunny climates. So these are the benefits of some discount vitamin supplements. How, then, do you find vitamins at discount prices? The easiest way is to purchase in bulk. There are those that form online clubs for vitamins and pay a weekly or monthly fee to join. When offers come online for specific supplements at low prices, they are purchased by the groups and distributed. You could do the same yourself with some friends, since it is generally cheaper to purchase 5 Kg of a vitamin that 500g. Your local health food store could also help you out since they are likely to be able to procure discount bulk prices from their supplier. Another way is to wait until your local store makes special offers, or seek offers in the press. These can often be found, but if you are concerned mainly with the common vitamins A, B complex, C, D and E then a large proportion of the population are interested in these and you should not find it difficult to sell several kilos of these. You will not only get yours free, but will a sizeable profit into the bargain. Anything between that and the normal price is an advantage for chemicals that are essential for life. One thing to always remember, buy reputable name brand vitamins because if the vitamins seem to cheap than you’re probably right. Name brand vitamins have quality and can be purchased at discount prices if you look long enough.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1604) Papaya- May Be A Fountain of Youth
Date:
May 31, 2007 02:09 PM
Papaya- May Be A Fountain of Youth
Seventy years ago, when the Social Security Administration was developed during the Great Depression, age 62 was recognized as average life expectancy. These days, getting older is a whole different ball game. Not only are people living well into their 80s and 90s, they’re living better, too. People well into retirement are mountain biking, kayaking, jogging and hiking, as well as gardening, golfing and attending concerts – sometimes for their first time. Everybody, it seems, is on the go, from ages of 22 to 92.
Of course, you don’t have to wait until retirement to start planning for a longer more vibrant life. The best way to ensure happier and longer years ahead is to start young.
Nobody wants to spend retirement in the doctor’s waiting room or have their golden years intruded upon with illnesses or infirmities. And, most importantly, we don’t want to feel 80 years old even though our driver’s license says we are.
These desires and demands are not just wishful thinking. Huge advances in the understanding of how men and women age are being made almost daily. These findings are helping to improve our chances of living long, healthy lives. And, some of the most impressive findings have shown that using nutritional supplements can help – in particular, a specially formulated papaya preparation is able to fight two of the primary reasons we get old – oxidative stress and immune system decline.
This issue of Ask the Doctor is going to share the anti-aging secrets hidden in the papaya and how this tropical fruit may hold the key to a long, vibrant life.
Q. Why papaya? What does papaya have that other fruits and vegetables don’t?
A. Not many American moms put a papaya in their kids’ lunch boxes and papaya pie has yet to gain a following. But this tangy tasting fruit is now appearing fairly frequently in the produce departments of most grocery stores and its popularity seems to steadily increase each year.
The papaya’s bright orange flesh is fairly fibrous and very slippery – slicing a peeled papaya is a little like slicing a bar of wet soap. The core is filled with little black seeds that look a lot like caviar. And while eating a papaya will give you a day’s worth of vitamins A and C as well as potassium taking Fermented Papaya Preparation (or FPP) might just give you an additional 30 years of healthy vibrant life.
Q. What exactly is Fermented Papaya Preparation (FPP)?
A. It’s a specialized nutritional supplement. Backed by more than 30 studies to date, FPP has been used in
Q. How was FPP developed?
A. Japanese scientists noticed that individuals with higher amounts of papaya in their diets experienced certain health benefits.
Researchers who study aging decided to look at the papaya’s chemistry to see if it might have properties that could contribute to longevity. Several plant chemicals in the papaya showed promise. And when they combined papaya with specific yeasts and traditional Japanese fermentation techniques, FPP was born. This unique substance was then subjected to scientific studies to see its health impact; they determined that FPP is a superior antioxidant, a powerful immune-booster, and one of
Q. How does FPP help people live longer and healthier?
A. While getting older is an indisputable fact of life, aging, per se, is not. We can’t do much about our annual birthdays and we really shouldn’t even if we could. Every age is a cause for celebration and every life experience, both the difficult and the sublime, should be treasured.
However, we don’t have to accept the consequences of aging that can make a mockery of the “Golden Years” - heart disease, Alzheimer’s disease, Parkinson’s disease, osteoporosis, arthritis, and cancer. Our parents and grandparents and the generations that preceded them might have had little say in how they aged. But we can. We can slow down the harmful effects of aging and FPP can help by reducing oxidative stress and immune system decline.
Additionally, fighting oxidative stress helps people retain their youthful appearance longer. Oxidative damage is the number one factor in facial aging.
Q. What exactly does oxidative stress mean and what does it have to do with aging?
A. One theory of aging is that harmful molecules called free radicals wreak havoc in our cells. Many of our body’s normal metabolic processes produce free radicals. For example, free radicals are a normal by-product in the production of ATP (the energy molecule) from glucose. Certain types of white blood cells destroy invading microbes by the production of free radicals. Free radicals are also formed by the many normal enzymatic actions that take place every minute every day.
However, outside sources can also cause free radical formation, as well. If we are exposed to pollutants in the environment, chemicals, additives and preservatives in the food we eat, or even direct sunlight, excess production of free radicals can occur, causing profound damage. This free radical frenzy is called oxidative stress, and is linked to almost every disease of aging including arthritis, heart disease, cataracts, Alzheimer’s disease, Parkinson’s disease, and cancer. In fact, the reason why these are called diseases of aging is because the longer we are alive, the longer we are subjected to these free radical assaults.
Q. How does FPP affect the decline of our immune systems as we age?
A. Our immune systems consist of specialized tissues, organs, and cells, including several different kinds of white blood cells. Each type of white blood cell works in specific ways to keep us healthy and free of disease. They not only stand guard – on the alert for invaders – they can fight and eradicate microbes, too.
However, as we age, our white blood cells become less efficient in keeping viruses and bacteria from infecting us. They often mistake invaders for good guys, like nutrients. As they age, white blood cells may recognize foreign invaders, but be too tired to fight and let them in. This age-associated immune decline also results in single cancer cells being able to “take hold” and grow into tumors. By the time the white blood cells realize their mistake, the cancer is a widespread disease.
That’s why older members of society have more urinary tract infections, more pneumonia, more cases of bacterial meningitis, tuberculosis, herpes zoster, and much more cancer than younger adults do. Moreover, mortality rates for these diseases are often 2-3 times higher among adults than younger people with the same disease.
FPP steps in and takes charge. One kind of white blood cells, the macrophage “eats” and digests bacteria, viral particles, and free radical fragments. Research has shown that FPP helps macrophages work faster and ingest more disease-causing microbes. Scientists have also discovered that FPP increases the production of a chemical protein called interleukin that’s secreted by macrophages. Interleukin plays an important part in wound healing and keeping minor infections from becoming major infections.
Another important immune system cell is the natural killer (NK) cell, a white blood cell that is continually on the prowl for cancer cells. As the immune system ages, NK cells have trouble “seeing” cancer cells. Researchers have discovered that FPP boosts the activity of NK cells. Increased NK cell activity can result in the increased killing of cancer cells as well as cells infected by viruses.
Q. How does FPP help protect us from free radical damage?
A. FPP contains unique and powerful antioxidants. Antioxidants are molecules that neutralize free radical damage. Antioxidants do this by donating an extra electron to the free radical without becoming frenzied or worked up into a free radical themselves. Although the antioxidant has donated an electron, it has a more stable “personality” and is less reactive. This action stops the domino effect and ongoing free-radical damage.
If you consider your body a temple, think of free radicals as stealing bricks from your temple’s foundation. FPP acts not only as policeman, but as a builder as well. It doesn’t just stop the theft of bricks; it helps create new ones, keeping the foundation strong and young.
FPP does this by affecting super oxide dimutase (SOD) and glutathione peroxidase (GPX), the very genetic pathways that eliminate free radicals from the system. FPP is more than an antioxidant – it doesn’t turn into a pro-oxidant if you happen to take a large dose the way standard antioxidants can. Consider it an “antioxidant plus.”
Since aging is largely determined by how well our bodies can fight oxidative damage, using FPP can slow down the clock as it bolsters natural abilities with its own potent neutralizing activities.
Q. What else does science say about FPP?
A. As the subject of over 30 clinical studies, FPP has been shown to inhibit dangerous Hydroxyl free radicals. In addition, it is also being considered for its immuno-protective effects.
Researchers and medical professionals have been studying FPP for years, tracking its effect on the immune system and aging. In fact, no less a personage then Dr. Luc Montagnier, co-discover of HIV 1 & 2 virus, has been conducting research on this natural immune booster.
Dr. Montagnier recommends using FPP as part of a tri-therapy (including antibiotics) that reduces the proliferation of the virus and stimulates the immune system. Since FPP has antioxidant and immuno-stimulative properties, it seems like an obvious choice for a combined approach to combating AIDS. Because of the higher free radical production in stage II of HIV infection, Montagnier believes that reducing this oxidative stress at the earliest stage of HIV infection may be a key factor.
In HIV-infected patients, the glutathione system is depressed even at the early stages. As part of a combination treatment, FPP increased the numbers of CF4 lymphocytes helped with weight gain and increased hemoglobin levels.
One scientific study showed the ability of FPP to inhibit dangerous Hydroxyl and Hydroxyl-like free radicals, while enhancing the production of protective super oxide. Other research by Dr. Lester Packer, a professor of Molecular Pharmacology and Toxicology at the
And, in one randomized, double blind, placebo-controlled clinical trial, patients with cirrhosis of the liver were given FPP or a placebo. The results showed that 81.2% of the patients survived in the FPP group compared to 38.5% of participants in the placebo group.
These studies and many others like it, show that FPP can neutralize the effects of oxidative stress on disease states as well as slowing the normal aging process.
Q. So if we can prevent oxidative damage to our cells AND prevent decline in our immune systems, how much longer can we expect to live?
A. Most theories of aging and almost all researchers who study aging claim there IS a limit to how long the human body can remain viable. However, the oldest age achieved so far was 128 by a woman named Ma Pampo who lived in the
Right now, Japanese women have the longest life span of any country in the world, with an average life expectancy of 85.93 years. Japanese men live an average 78.87 years.
Q. Is FPP safe?
A. Yes, it is. Many health-conscious people in
Q. What is the recommended dosage level of FPP?
A. Dosages of FPP vary depending on individual needs and usage. For basic anti-aging support, 3 grams per day is fine. For additional support, up to 9 grams per day is recommended. To add a boost to your immune system when you need it, start out with 6-9 grams a day for the first 2-3 days (at the beginning of a cold, for example) and then move back down to 3 grams per day.
For individuals looking for optimum immune support, Dr. Montagnier advises morning and evening doses, preferably on an empty stomach.
Conclusion
As
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1555) This sour Indian fruit can have a sweet appetite-stifling effect
Date:
May 26, 2007 05:44 PM
Stay satisfied with garcinia This sour Indian fruit can have a sweet appetite-stifling effect. It’s funny how modern science continues to support ancient systems of herbal healing. Such is the case with garcinia: the yellowish, pumpkin like fruit of the Garcinia cambogia tree, log valued in tropical Asian cooking for its sweetly acidic taste, is a traditional Indian remedy for digestive problems that is also used to make meals more filling. Today, garcinia (also known as brindleberry and Malabar tamarind) is used in natural weight-loss products based on research supporting its stomach satiating powers. Scientists also believe that garcinia helps block fat formation and regulate glucose (blood sugar) usage vital functions in an increasingly overweight world. Filling up Faster One reason so many people losing the battle of the bulge is that temptations to eat – and eat – are absolutely everywhere, often as the focal points of clever and well designed advertising campaigns. (Remember the slogan “belch’a can’t eat just one”?) To make matters worse, restaurants often serve overly generous portions and experiments have shown that the more food you serve, the more people will consume. For example, The answer would seem simple – just eat less. But knowing when to say when isn’t easy. That’s where garcinia comes in, specifically an extract taken from the rind called HCA (Hydroxycitric acid). In laboratory animals HCA has upped levels of serotonin, a brain chemical that helps suppress appetite and elevate mood, which might help take the edge off the depressing and binge-eating urges that often affect would-be weight losers. At the same time HCA appears to reduce levels of another substance in the brain called neuropeptide Y, which enhances appetite (Experimental Biology meeting 4/06). Garcinia gems What is it: the pumpkin-like fruit of the garcinia cambogia tree; this Indian native is used in cooking and in Ayurveda, the country’s system of traditional medicine. What is does: A popular ingredient in natural weight-loss aids, garcinia is being investigated for possible fat blocking and appetite-suppressing functions; it may also help regulate glucose (blood sugar). Fat Smack down The fat that stubbornly clings to your frame doesn’t always start out that way. In many cases, your body actually creates fat from excess carbohydrates (such as the icing encrusted doughnut you couldn’t pass u at breakfast). If you don’t burn off those extra carbs through exercise, they are broken down into citrates that are then transformed into the building blocks of body fat. This process is controlled by an enzyme called citrate lyase; HCA interferes with this crucial enzyme, an action that inhibits fat formation. Researchers believe the body uses those extra carbs to provide more energy; this mechanism may also have the happy side effect of further checking appetite. In addition, results from a Dutch lab study indicate that garcinia may blunt sugar-induced increases in glucose, which can help forestall diabetes development. Garcinia works best when teamed with out nutrients and herbs, such as chromium, green tea and forskolin. In one investigation, over weight people who stuck to a supervised diet and exercise program supplemented with a combination of HCA, chromium and another herb called Gymnema lost body weight and mass, and showed improved fat burning capacity (Nutrition Research 1/04). This modern usage mirrors Ayurveda’s ancient precepts, according to which individual remedies are generally used in combination for more effective results. Looking to get your meals more staying power? Then look for garcinia in your favorite weight loss formula. –Lisa James
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1542) Supplements good for reducing stress and boosting energy!
Date:
March 26, 2007 02:05 PM
Vitality 101
More and more Americans are feeling overworked, overtired, and overcome by life’s demands. We just do not have the energy we need to meet our responsibilities to the people we care about. More importantly, we don’t even have the energy to have fun! It seems that a constant feeling of fatigue has become part of the American way of life.
Research has shown that the same processes that cause lack of energy can rob us of sleep, saddle us with excess weight, disrupt our hormonal balance, and create significant amounts of stress in our daily lives. Chronic stress can dramatically contribute to fatigue, sleep disorders, irritability, and anxiety. The research simply confirms what most of us already know – uncomfortable stress can really wear us out mentally and physically! It can take away the satisfaction of a job well done. It can take away our ability to believe in ourselves. And, sadly and maybe most importantly, continual stress can take the fun and joy out of life.
In a separate issue of Ask the Doctor, we discuss the energy and sleeping needs of people suffering from chronic fatigue syndrome and fibromyalgia. In this issue, I discuss the 3-step process I call “Vitality 101.” People do not have to accept pain, insomnia, or fatigue. It’s time for everyone to feel great and have a life they love!
Step 1 – Nutrition
Good overall nutrition is important for everyone! As a foundation product to support energy levels, a powdered drink mix is a pleasant, easy way to ensure that you are taking all of the necessary vitamins, minerals, and amino acids that you need to have great energy all through your day.
The following chart lists the most critical ingredients. You can see that almost all of the vitamins and minerals work together to help improve energy levels and overall health.
In addition to the powdered energy drink mix, it is important that you also take a high potency vitamin B-complex supplement. This should include niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, which are especially important to restore the energy production needs of your body. It is also critical to get enough water, as most Americans are chronically dehydrated.
Step 2 – Rest Your Body
Having trouble sleeping is one of the most troubling symptoms of stress. While the stress is wearing us down and making us tired, it’s also keeping us tense and unable tot relax. The result? That easy drift into sleep becomes harder and harder. And if we are lucky enough to actually get some shut-eye, stress will often wake us up, sometimes several times a night.
This occurs because excess stress suppresses the sleep center in the brain. It is important to break the “stress/insomnia cycle” early, before it results in pain and hormonal and immune dysfunction!
Because good quality sleep is how the body repairs and re-energizes itself, it may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Look for a supplement that has a blend of herbs that promote deep sleep, such as valerian, L-theanine, hops, passionflower,
Step 3 – Manage Excess Stress Levels
In this fast paced world, it is important to learn to manage the stressor in our lives. Glandular extracts, such as raw adrenal extract, can offer natural support to help our bodies deal with the effects of stress and, in turn, can boost your energy levels. Exercise is another stress buster. Using your body physically is important for good health. Find something that is fun for you, however, or you are unlikely to stick with it!
Q. Does stress zap my energy in any other ways besides making me lay awake at night and causing me to be a zombie the next morning?
A. Most people are familiar with the body’s dramatic response to an emergency. The heart pounds, the muscles constrict, and the lungs expand – and while this is happening, we are capable of greater than normal strength and speed. This response is the body’s way of rescuing itself when faced with an emergency. We don’t have to think about it to make it happen. It’s automatic.
The same can be said of a chronic stress response. Whether we’re late for a business meeting because we’re stuck in traffic, or worrying about how we are going to pay for our children’s college tuition, our response to stress happens automatically. The difference between the two is that the body’s response in an emergency starts and resolves itself quickly. The response to being stuck in traffic may not.
The body makes the “stress hormone”, cortisol, to handle the normal stresses of day-to-day living. But in an emergency situation, the adrenal glands, located above the kidneys, secrete increased amounts of this hormone until the emergency passes. Then the body returns to its normal function. Unfortunately, however, chronic stress is more complex. When our body is subjected to increased amounts of the hormone, cortisol, for an extended time, it can lead to a condition known as “adrenal burnout” or “adrenal fatigue.” While it’s true that very large amounts of cortisol can have damaging effects on our hormones, too little cortisol doesn’t allow us to respond to stress properly. It’s really a matter of balance.
Q. How can I control the stress in my life and re-energize?
A. Many people who are under constant stress may have adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.
The good news is that changes in our hormone levels can return to normal when stress is decreased. The key in learning how to deal with daily stress is to allow the body to return to its normal state. I discuss additional techniques for coping with stress in my recent book Three Steps to Happiness! Healing Through Joy (see my website, www. jacobeitelbaum .com, for more information). In addition to stress control, it is important to supplement your adrenals with a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy, which uses the concentrated forms of bovine (cow) or porcine (pig) glands, can improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacked and thus repaired the malfunctioning gland.
Adrenal Extract
If you are one of the unlucky folks with stressed-out adrenal glands, you should see great results from taking raw adrenal supplements. Be sure to buy adrenal extract supplement that contains both whole adrenal and cortex adrenal.
The best adrenal supplement should also contain vitamin C, vitamin B6, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.
Liver Extract
Did your grandmother ever tell you to eat your liver so that you didn’t get “tired blood?” Well, it turns out that she was right. Liver extract is another glandular extract that can help improve energy levels.
Liver extract is an excellent source of highly bioavailable nutrients including iron, B vitamins (especially B12), and other minerals. The stamina and energy-enhancing benefits of liver are widely touted. Liver extract has been shown to support healthy function of the liver and increase the energy levels inside our body.
Because heat will destroy the key components in the liver, a high quality liver extract supplement should be cold-processed and encapsulated to enhance speed and absorption of nutrients from liver. A high quality aqueous liver extract supplement should also contain vitamin B12 to support healthy blood iron and oxygen levels to energize.
Q. It will be great to get a good night’s sleep. Are there also any other natural alternatives that could help promote relaxation and increase my energy levels during the day?
A. Yes, there are. Rhodiola rosea is an all-natural herb that has long been used to help relieve stress and increase energy. Rhodiola has also been used to lift our moods, improve sexual satisfaction, and even help in certain nervous system disorders. First used in Siberia and
In clinical trials, the most effective Rhodiola rosea extract was found to contain 3% rosavins and 1% salidroside. While there are many Rhodiola supplements in health food stores, only those containing these specific amounts can provide the best results.
Lifestyle Treatments
Altered digestion, food intolerances, decreased energy, fatigue, cognitive problems, and sleeplessness create the need for changes in daily living routines. These can include alterations in diet; exercise modifications; alterations in activities of daily living according to one’s energy level; and sleep/rest management. All may require the assistance of a professional clinician, such as a chiropractor, nutrition specialist, physical and/or occupational therapist, mental health professional, or sleep therapist.
Conclusion
Super busy lives demand super strength nutrition. Begin each day with a powdered nutritional supplement after getting at least 8 hours of sleep each night. In addition to the nutritional beverage mix, a vitamin B complex supplement should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients to combat your fatigue. Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Rhodiola rosea, and ginseng can offer additional natural nutritional support in your busy life to boost your energy levels. These nutritional supplements can be used daily and you will feel energized to get through each day’s challenges and opportunities!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1496) Revita
Date:
March 08, 2007 12:27 PM
Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product. Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class. To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules. Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth. Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available. Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects. In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls." In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded: • The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls. • 78.9% of subjects showed an increased mean value of hair diameter. • "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness." Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results. Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings: • Total Number of Hairs: Significantly Increased • Total Number of Terminal Hairs: Significantly Greater • Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher • Hair Follicle Activation: Intensive In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials. Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss. Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area. The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp. Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles. Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E. Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and Hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth. Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing. Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial. If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months. Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study. The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo. Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion. After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier. Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss. MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM. The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes. MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications. Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness. The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone. According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss. The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study. Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate. Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate. The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased. Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft. Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids. Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth. L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications. The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth. Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day. In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing. Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic. Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth. Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle. Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss. After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week. This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted. Q. Is Revita safe ? A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe. Q: Can I use hair sprays, mousses, gels, etc.? A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita. Q: Can I have my hair colored or permed while using Revita ? A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita. Q: What is SLS/SLES free ? A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health. Q: Can I blow dry my hair after using Revita ? A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita. Q: Who is a candidate for Revita ? A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately. Q: What type of results should I expect with Revita ? A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment. Q. Does Revita have any systemic side effects ? A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically. Q. Does Revita work for women? A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair. Q. I am using other topical treatments. Can I use Revita at the same time ? A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair. Q. Do I need to use Revita for a long time ? A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp. Q: Is stress a factor in hair loss? A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1480) Vitamin D May Show Benefits Against Breast and Colorectal Cancer
Date:
February 27, 2007 02:09 PM
Review and meta-analysis of several studies led researchers from several institutions to determine that an increased daily intake of vitamin D may significantly correlate with reduced incidences of colorectal and breast cancer. The breast cancer study pooled dose-response data from two earlier studies of 1,760 subjects. Subjects with the highest serum concentrations of 25-Hydroxyvitamin D, or 25(OH)D (50 nanograms per milliliter), had a fifty percent lower risk of breast cancer compared to those with the lowest blood concentrations; less than or equal to 10 nanograms per milliliter. The colorectal cancer meta-analysis looked at fiver studies of 1,448 caucasian subjects. The authors estimate a two-thirds reduction in incidence with serum concentrations of 46 nanograms per milliliter, corresponding to a daily intake of 2,000 IU of vitamin D3. the researchers state the best way to achieve these concentrations is a combination of diet, supplements and 10 to 15 minutes per day in the sun. (Journal of Steroid Biochemistry Medicine, volume 32, Number 3, Pages 210-216)
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1474) This is sour Indian fruit can have a sweet appetite stifling effect.
Date:
January 13, 2007 02:44 PM
It’s funny how modern science continues to support ancient systems of herbal healing. Such is the case with Garcinia: The yellowish, pumpkin like fruit of the Garcinia Cambodia tree, long valued in tropical Asian cooking for its sweetly acidic taste, is a traditional Indian remedy for digestive problems that is also used to make meals more filling. Today, Garcinia (also known as brindleberry and Malabar tamarind) is used in natural weight-loss products based on research supporting its stomach satiating powers. Scientists also believe that Garcinia helps block fat formation and regulate glucose (blood sugar) usage—vital functions in an increasingly overweight world. Filling Up Faster One reason so many people are losing the battle of the bulge is that temptations to eat-and eat—are absolutely everywhere, often as the focal points of clever and well designed advertising campaigns. (Remember the slogan “belch’a can’t eat just one”?) To make matters worse, restaurants often server overly generous portions and experiments have shown that the more food you serve, the more people will consume. For example, Chicago moviegoers ate 45% more popcorn from larger containers even when they were given stale product (Food Quality and Preference 1/01). The answer would seem simple—just eat less. But knowing when to say when isn’t easy. That’s where garcinia comes in, specifically an extract taken from the rind called HCA (Hydroxycitric acid). In laboratory animals HCA has upped levels of serotonin, a brain chemical that helps suppress appetite and elevate mood, which might help take the edge off the depression and binge-eating urges that often affect would-be weight losers. At the same time HCA appears to reduce levels of another substance in the brain called neuropeptide Y, which enhances appetite (Experimental Biology meeting 4/06). Garcinia Gems What it is: the pumpkin-like fruit of the Garcinia cambogia tree; this Indian native is used in cooking and in Ayurveda, that country’s system of traditional medicine What it Does: A popular ingredient in natural weight-loss aids, garcinia is being investigated for possible fat blocking and appetite suppressing functions; it may also help regulate glucose (blood sugar). Fat Smackdown The fat that stubbornly clings to your frame doesn’t always start out that way. In many cases, your body actually creates fat from excess carbohydrates (such as the icing encrusted doughnut you couldn’t pass up at breakfast). If you don’t burn off those extra carbs through exercise, they are broken down into citrates that are then transformed into the building blocks of body fat. This process is controlled by an enzyme called citrate lyase; HCA interferes with this crucial enzyme, an action that inhibits fat formation. Researchers believe the body uses those extra carbs to provide more energy; this mechanism may also have the happy side effect of further checking appetite. In addition, results from a Dutch lab study indicate that garcinia may blunt sugar-induced increases in glucose, which can help forestall diabetes development. Garcinia works best when teamed with other nutrients and herbs, such as chromium, green tea and forskolin. In one investigation, overweight people who stuck to a supervised diet and exercise program supplemented with a combination of HCA, chromium and another herb called Gymnema lost body weight as mass, and showed improved fat burning capacity (Nutrition Research 1/04). This modern usage mirrors Ayurveda’s ancient precepts, according to which individual remedies are generally used in combination for more effective results. Looking to give your meal more staying power? Then look for garcinia in your favorite weight loss formula. –Lisa James.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1445) Which Calcium is Best?
Date:
October 17, 2006 03:52 PM
Customers walking into a health food store today are faced with a vast array of calcium supplements. They might ask: which one should I pick? Which one is best? Not easy questions to answer. All calcium forms will accomplish the same task: providing your body with a nutrient that it needs to build healthy bones and teeth; however, which form of calcium has the features that you want in a calcium supplement? Looking at shelves of calcium products is kind of like shopping for a car; there are many makes and many models—some are basic and others are more sophisticated. Fortunately, there are many forms of calcium to satisfy your needs. Like the car lot, a health food store offers many options; therefore, you have to select a calcium product that consumers will feel confident in taking regularly and that will provide the most benefit. Some consumers have done research and will come armed with information. They have already made choices based on advertising, word-of-mouth or an article they have read. They already know the form of calcium they want, be it a “Ferrari” or a “Ford.” If the client doesn’t have a specific preference: asking these basic questions will help in the selection process: 1. Do you prefer tablets, capsules, softgels, liquid or powder?
2. Do you have high or low stomach acid?
3. Do you have absorption issues?
What is calcium? Calcium (Ca) is one of the most important minerals found in our bones and teeth—99 percent of body calcium is found there. But the calcium molecule does not like to travel alone and, in its more basic state, it comes bounded to carbon (C), Oxygen (O), and/or hydrogen (H) molecules or in more complex form, it is bonded to organic or amino acids that act as stabilizing carriers. On most labels, the amount of calcium listed actually indicates the pure or elemental calcium because it is that amount of the calcium that is deemed important to our daily supplementation, not the complex of the materials with which it is bonded. Where does calcium come from? Other than the calcium found in bone, the only natural form of calcium found in nature is calcium carbonate, a calcium molecule bonded to one molecule of carbon and three molecules of oxygen (CaCO3). One of the most common minerals on the face of the earth, calcium carbonate is called calcite, aragonite or vaterite by geologists. In its geological form, it constitutes approximately four percent, by weight, or the earth’s crust. Commercial sources of calcium carbonate used to make supplements are: limestone, dolomite, oyster cell, egg shell, coral and sea water (have you ever seen that white deposit left by hard water? That’s mostly calcium carbonate). Calcium carbonate is the starting material for all other forms of calcium supplements. From this starting material, calcium can be reduced to more concentrated forms, such as oxide or hydroxide or it can be chelated (bonded) to organic acids and amino acids to help support enhanced absorption. Lets look more closely at the different forms of calcium that are available as supplements. Calcium Oxide (CaO): this form is 71 percent elemental calcium and is also called “lime” commercially. This is one of the oldest and most inexpensive forms of calcium used in a variety of commercial applications and it is occasionally used in supplements where space and price are a factor. It sometimes can be found in inexpensive mass market calcium/mineral combinations or multivitamin/mineral products and in a unique algal calcium from Japan. Unfortunately, CaO is a strong alkali that may cause stomach distress, which is why it isn’t often used in health food supplements. Calcium Hydroxide (CaHO): at 54 percent elemental calcium, it is the next highest source of elemental calcium and is also known commercially as “slaked lime.” It is used where space is an issue. Although it is also a strong alkali, it is more stable than calcium oxide. It is most often used as a component of multi-mineral formulations or in addition to other forms of calcium (i.e., calcium citrate) to provide potency where space is an issue. It is not often used as a single ingredient in health food supplementation. This is for people who want a high dosage of calcium from a minimum amount of pills in multi-mineral formulas. Calcium Carbonate (CaCO3): at 40 percent elemental calcium, it is the most widely used form of calcium in single ingredient calcium supplements as well as combination supplements. Inexpensive and an abundant source of elemental calcium, it is the only form of calcium found in nature outside of bone. It is the primary form of calcium used in the mass market and in antacid products. This is for people who have high stomach acid and who need a buffering type of calcium. Also for people who want a high dose of calcium in a minimum amount of pills. Calcium Citrate: at 21 percent elemental calcium, it is one of the most popular forms of calcium supplements in the health food market as well as the mass market. This calcium salt does not lower stomach acid as much as calcium carbonate. This calcium salt is usually recommended for people who have low stomach acid, have had stomach surgery or who need a form of calcium that will not lower their stomach acid further. Calcium Gluconate and Lactate: these two forms of calcium are high soluble. Since the amount of elemental calcium is much lower (9 percent and 13 percent respectively), they are used more often in powder form and mixed with liquids or food. When mixed in a beverage, the calcium is already dissolved and is ready to be absorbed. This is the best calcium salt for people who have overactive bowels, who have trouble swallowing pills or who don’t like the taste of pre-formed liquid calcium supplements. These calcium powders can be mixed in juices or smoothies or added to food as they are virtually tasteless. Calcium Orotate and Asporotate: In the mid 20th century, Dr. Hans Nieper, a German scientist, advanced a theory that orotic and aspartic salt forms of calcium are transported directly to cell membranes for better absorption. The Solaray brand developed an asporotate formula, which combines three organic acids: aspartic acid (-Asp), orotic acid (-oro) and citric acid (-tate) into one product. The asporotate formula has become one of the most popular calcium formulas and is exclusive to the Solaray brand. This product is for customers who appreciate the idea of combining the enhanced absorbability of three organic acids into one. Aspartate and citrate are also part of the krebs (energy) cycle and are natural to the body’s metabolic systems and, according to Neiper, calcium Orotate and Aspartate are mineral transporters that enter into the cells to facilitate enzymatic actions rather than being extra-cellular. For people who believe that intracellular calcium is of importance, calcium Orotate and asporotate may be good choice. Calcium Hydroxyapatite: this is another “natural form of calcium usually as a mineral ash form bovine source bone. Bone meal is also a form of calcium from bovine bone. These forms of animal derived calcium are for customers who want a source that is closest to their own bone matrix. Not for vegetarians. Calcium Amino Acid Chelates (*HVP): this form is calcium carbonate bonded (Chelated) to a form of amino acid complex such as whole rice concentrate or other grain source. This form is for customers who want the additional bioavailability of amino acids. Calcium AEP: Another form of calcium endorsed by Dr. Hans Nieper who theorized that calcium would cross the cell membranes more readily when it was combined with phosphatidyl ethanolamine or Amino Ethanol Phosphate (AEP), a nutrient found in nerve sheaths. This highly specialized form is for very educated customers who are proponets of Hans Niepers theory. So, which form is best? Calcium, like cars, comes in a variety of forms. Isn’t it wonderful that we have so many choices? The point is, there is no best one, there are only individual choices. Although we have our favorites, taking a calcium supplement, regardless of which one it is, should:
Our primary concern when choosing a calcium supplement should be to provide our body with the right amount of calcium daily so that our skeleton and teeth can maintain proper mineralization and strength as the cells continuously break down and rebuild. The type of calcium complex we prefer is entirely up to us. *HVP = Hydrolyzed Vegetable Protein
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1411) 7-Syndrom Healing and 5-HTP
Date:
June 07, 2006 03:49 PM
Boomer Breakthrough – Keeping in the Game If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-Hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves. Mood, Anxiety and Depression Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use. How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels. Serotonin the Antiaging Neurotransmitter Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients. Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period. 5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin. It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia. Pain, Per-menopause and PMS 5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants. Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability. Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller. Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety. Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain. Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1306) Best Sugar Balance Svetol (green coffee extract)
Date:
May 05, 2006 06:30 PM
Ingredients Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids. In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.* Benefits Maintains healthy blood sugar levels when used as a part of the diet* CHLOROGENIC ACIDS Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of Hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against Hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1 Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3 Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the Hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the Hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the Hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the Hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5 It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism. A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6 RESEARCH ON SVETOL® Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results. In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7 Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption. The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.* SAFETY Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7 *This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antiHydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4. 2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402. 3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7. 4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on Hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10. 5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15. 6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1258) Benefits of Best Alpha Lipoic 35!
Date:
February 12, 2006 03:11 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1217) Olive Leaf Extract
Date:
January 02, 2006 10:17 AM
In today’s stressful world, immune system health is more important than ever. History has proven that no matter what we do to combat viruses, bacteria and parasites, they have the remarkable capability to mutate for survival, often returning in a more virulent form than before. New strains of the flu and other microbial invaders are being discovered at an alarming rate, and modern medicine is constantly on the defensive. At the time this was written, the Centers for Disease Control (CDC) in Atlanta is predicting a “bad flu season” because a “killer drift variant” strain of flu had been discovered, called type A Fujian. This new strain has already caused deaths abroad, and vaccinations are strongly recommended, especially for the very young and the elderly. However, mutating microbes are only part of the problem confronting our immune systems. Factors such as environmental pollution and over-processing of foods are believed by many researchers to play a major role in many health conditions. Which means, more than ever before, you need to make sure your immune system is functioning at peak efficiency. Fortunately, there are a number of natural products available that can assist you in reaching this goal. One of the most effective discovered to date is Olive Leaf Extract (OLE). Natural olive leaf extract is derived from the olive tree (Olea europaea), which happens to have a very long and interesting history. One of the most revered botanicals, the olive tree is mentioned numerous times in the Bible. One of the earliest and most powerful mentions is the delivery of the olive branch to Noah by a dove, a sign that the floodwaters were receding and life was returning. The olive tree was, and still is, a life-giver. It’s fruit is used for food, and the oil is used for cooking and as a source of light to ward off the darkness. Ancient cultures soon discovered that the various components of the olive tree provided a myriad of health benefits as well, benefits confirmed by modern science. Extract of olive leaves is one of the best, if not THE best, natural antimicrobials and antioxidants ever discovered.* Oddly enough it might have been well recognized in this role much sooner since it was reported in the mid-1850’s that a bitter tea brewed from olive leaves might be a potential cure for malaria. However, not all great discoveries are immediately recognized as valuable, and physicians of that era didn’t give much credence to the reports. It wasn’t until decades later that a simple analysis conducted on olive leaves led to the discovery of an active component, the phenolic compound oleuropein, which has since been associated with many health benefits. More recently, numerous studies have been conducted on olive leaves and the active components found in the leaves, with a preponderance of positive results. A 1999 study conducted at the University of Rome assessed the antimicrobial activity of oleuropein and Hydroxytyrosol, two of the most active components in olive leaf extract. They were pitted against many different bacterial strains, including salmonella and staphylococcus, in vitro. The study concluded, “Olea europaea can be considered a potential source of promising antimicrobial agents” for the support of intestinal and respiratory health.* 4 A 2002 study conducted at the University of South Australia compared the effectiveness of some of the typical components of the Mediterranean diet, including oleuropein and Hydroxytyrosol, as reactive oxygen species inhibitors and free radical scavengers. Researchers also examined their capability in protecting against low-density lipoprotein oxidation in vitro. Results clearly indicated that these components are potent inhibitors of free radical generation, as well as effective free radical scavengers.* 5 NOW® Foods carries a number of olive leaf extract products, including our Olive Leaf Extract 500mg, standardized to contain 6% oleuropein, our Extra Strength product with 18% oleuropein and 100mg of Echinacea Extract, and Olive Leaf Glycerite liquid, which contains 18% oleuropein. Why would you want a standardized Olive Leaf Extract product over a whole herb Olive Leaf product? We’re glad you asked! Standardization allows for consistently effective herbal products because the active ingredient, or marker compound, is accurately identified and measured, ensuring that the product delivers a certain minimum level of the active component or components. In simpler terms, standardized herbal products allow the consumer to obtain the benefits of an herb without having to consume massive quantities because there is a much greater concentration of active components, which also improves the effectiveness of the herbal product. Purchasing standardized Olive Leaf with a guaranteed concentration of oleuropein is a smart choice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1147) Olive Leaf Extract - for immune support
Date:
January 02, 2006 10:11 AM
“STANDARDIZED HERBS FOR IMMUNE SYSTEM SUPPORT”Olive Leaf Extract
References * This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1146) Vitamin C FAQ's
Date:
December 27, 2005 05:11 PM
Vitamin C FAQ'sWhat is Calcium Ascorbate? Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium. What does Calcium Ascorbate do? Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as Hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals. Is this a necessary vitamin or can our bodies make enough to satisfy our needs? Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement. What is the function of the Citrus Bioflavonoids? Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity. Why are there color variations in your different Vitamin C products, and are they safe to take? Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color. Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation. Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid. NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium. Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1099) Tru-E Bio Complex
Date:
December 08, 2005 04:58 PM
Tru-E Bio Complex TMNeil E. Levin, CCN, DANLA 7/27/05LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements. NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32 Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32 This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7 Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13 ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols. All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU). Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet. Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market. We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32 Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23 SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal. SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds CAUTIONS: None. SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient. GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. REFERENCES:
1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1000) TMG Fact Sheet
Date:
December 07, 2005 02:13 PM
TMG Fact SheetNeil E. Levin, CCN, DANLA 03/07/05LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups. MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine. TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals. Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot. ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid. TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures. DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably. SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed. COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: General: Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791 Methylation: Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review]. Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30. Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review]. Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31. Charlton CG, Mack J. Substantia nigra degeneration and tyrosine Hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61. Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5. Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93. Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review]. Homocysteine: Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8. Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361 Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203 Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266 Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review]. van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83. Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50. Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53. Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499 Liver function: Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German]. Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2. Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5. Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329 Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277 Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6. Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887 Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612 Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61. McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907 Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55. Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439 Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German]. Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644 Autism & Seizures: Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1. Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82. Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6. Immunity: Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6. Safety: Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=988) Allibiotic CF Fact Sheet
Date:
December 07, 2005 01:37 PM
Allibiotic CF Fact SheetNeil E. Levin, CCN, DANLA 03/09/05LIKELY USERS: People seeking support of the immune system and intestinal flora KEY INGREDIENTS: Allicin (“AlliSure” patented, stabilized allicin from fresh garlic); Olive Leaf Extract (Olea Europaea with 18% minimum Oleuropein content); Elderberry extract, from fruit/berry, 60:1 concentrate (equivalent to 2,500 mg. of fresh berries of Sambucus nigra); Oil of Oregano (wild oregano from Origanum vulgare) ImmunEnhancer AG (trademarked Arabinogalactan from Larch Tree, Larix occidentalis) MAIN PRODUCT FEATURES: AlliSure is the clinically tested, patented and stable form of allicin. Not allicin potential, but actual allicin. Allicin represents the immune supporting nutrients of raw garlic, and is chemically similar to penicillin, though with different physical properties. AlliSure shares garlic’s abilities to help maintain healthy cholesterol and blood pressure levels, and also has been shown to raise levels of a key T cell to enhance immune system function. Like raw garlic, AlliSure has antimicrobial properties linked to its ability to react with sulfur-containing metabolic enzymes. Allicin is also shown in studies to play a role in controlling blood sugar and abnormal cell growth. Black Elderberries have strong antioxidant properties, containing flavonoids like anthocyanidins. They have been studied in relation to inhibition of viral replication and of minor inflammations. Olive Leaf has been used as an antioxidant, cholesterol and blood viscosity regulator, and vasodilator. But its most important use has been as a way to help the body deal with undesirable organisms in the vital respiratory and intestinal areas. Oil of Oregano (wild oregano, wild marjoram) contains carvacrol and thymol, which are responsible for much of its antimicrobial activities. It also has some anti-inflammatory effects. Arabinogalactan from Larch tree bark (ImmunEnhancer AG) can help speed the immune system’s response to undesirable organisms and is often compared to Echinacea. It has also been shown to promote the growth of beneficial intestinal bacteria. ADDITIONAL PRODUCT INFORMATION: Patented and trademarked ingredients enhance quality controls and have clinical research. Rosemary Oil provides antioxidant protection for the capsule contents. Enteric coating protects the capsule from stomach acid to deliver its contents past the stomach. This helps to assure full potency and reduces the possibility of the oils repeating. SERVING SIZE & HOW TO TAKE IT: One softgel twice daily, preferably with meals. Try one before using the full dose. COMPLEMENTARY PRODUCTS: Probiotics, Antioxidants, D-Flame CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Discontinue use if any uncomfortable side effects occur. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:ALLICIN: Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Adv Ther. 2001 Jul-Aug;18(4):189-93. (AlliSure was used in this study.) Abramovitz D, Gavri S, Harats D, Levkovitz H, Mirelman D, Miron T, Eilat-Adar S, Rabinkov A, Wilchek M, Eldar M, Vered Z. Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet. Coron Artery Dis. 1999 Oct;10(7):515-9. PMID: 10562920 Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997 Oct;41(10):2286-8. PMID: 9333064 Cellini L, Di Campli E, Masulli M, Di Bartolomeo S, Allocati N. Inhibition of Helicobacter pylori by garlic extract (Allium sativum). FEMS Immunol Med Microbiol. 1996 Apr;13(4):273-7. PMID: 8739190 Chowdhury AK, Ahsan M, Islam SN, Ahmed ZU. Efficacy of aqueous extract of garlic & allicin in experimental shigellosis in rabbits. Indian J Med Res. 1991 Jan;93:33-6. Eilat S, Oestraicher Y, Rabinkov A, Ohad D, Mirelman D, Battler A, Eldar M, Vered Z. Alteration of lipid profile in hyperlipidemic rabbits by allicin, an active constituent of garlic. Coron Artery Dis. 1995 Dec;6(12):985-90. PMID: 8723021 Elkayam A, Mirelman D, Peleg E, Wilchek M, Miron T, Rabinkov A, Oron-Herman M, Rosenthal T. The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Am J Hypertens. 2003 Dec;16(12):1053-6. PMID: 14643581 Feldberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Sundstrom DC, Thompson NH. In vitro mechanism of inhibition of bacterial cell growth by allicin. Antimicrob Agents Chemother. 1988 Dec;32(12):1763-8. Focke M, Feld A, Lichtenthaler K. Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase. FEBS Lett. 1990 Feb 12;261(1):106-8. Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. Nutr Cancer. 2000;38(2):245-54. PMID: 11525603 Patya M, Zahalka MA, Vanichkin A, Rabinkov A, Miron T, Mirelman D, Wilchek M, Lander HM, Novogrodsky A. Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Int Immunol. 2004 Feb;16(2):275-81. PMID: 14734613 Rabinkov A, Miron T, Mirelman D, Wilchek M, Glozman S, Yavin E, Weiner L. S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):144-153. PMID: 11118647 Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998 Feb 2;1379(2):233-44. PMID: 9528659 Sela U, Ganor S, Hecht I, Brill A, Miron T, Rabinkov A, Wilchek M, Mirelman D, Lider O, Hershkoviz R. Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Immunology. 2004 Apr;111(4):391-9. PMID: 15056375 Shadkchan Y, Shemesh E, Mirelman D, Miron T, Rabinkov A, Wilchek M, Osherov N. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J Antimicrob Chemother. 2004 May;53(5):832-6. Epub 2004 Mar 24. PMID: 15044429 Tsai Y, Cole LL, Davis LE, Lockwood SJ, Simmons V, Wild GC. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Planta Med. 1985 Oct;(5):460-1. PMID: 3001801 Uchida Y, Takahashi T, Sato N. [The characteristics of the antibacterial activity of garlic (author's transl)] Jpn J Antibiot. 1975 Aug;28(4):638-42. PMID: 1099271 Yasuo Yamada and Keizô Azuma. Evaluation of the In Vitro Antifungal Activity of Allicin. Antimicrob Agents Chemother. 1977 April; 11(4): 743–749. ELDERBERRY: Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 423. Gruenwald J, Brendler T, Jaenicke C, et al. (eds). PDR for Herbal Medicines. Montvale, NJ: Medical Economics, 1998, 1116–7. Mascolo N, Autore G, Capasso G, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987;1:28–31. Murkovic M, Abuja PM, Bergmann AR, et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. Feb2004;58(2):244-9. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press, 1996, 104–5. Yesilada E. Inhibitory Effects of Turkish Folk Remedies on Inflammatory Cytokines: Interleukin-1Alpha, Interleukin-1Beta and Tumor Necrosis Factor Alpha. J Ethnopharmacol. Sept1997;58(1):59-73. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radical Biol Med 2000;29:51–60. Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995;1:361–9. OLIVE LEAF EXTRACT: American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001. Bennani-Kabchi N, et al. Effects of Olea europea var. oleaster leaves in hypercholesterolemic insulin-resistant sand rats. Therapie. Nov1999;54(6):717-23. Bisignano G, et al. On the in-vitro antimicrobial activity of oleuropein and Hydroxytyrosol. J Pharm Pharmacol. Aug1999;51(8):971-4. Gonzalez M, et al. Hypoglycemic activity of olive leaf. Planta Medica. 1992;58:513-515. Visoli F, et al. Oleuropein protects low density lipoprotein from oxidation. Life Sciences. 1994;55:1965-71. PDR for Herbal Medicines, 2nd edition. Montvale, NJ: Medical Economics Company; 2000:557. Petroni A, et al. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.Thromb Res. Apr1995;78(2):151-60. Pieroni A, et al. In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves. Pharmazie. Oct1996;51(10):765-8. Zarzuelo A, et al. Vasodilator effect of olive leaf. Planta Med. Oct1991;57(5):417-9. OREGANO OIL (OIL OF OREGANO, WILD OREGANO, WILD MARJORAM): Dorman HJ, et al. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. Feb2000;88(2):308-16. Force M, et al. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. May2000;14(3):213-4. Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999;86:985–90. Kelm MA, Nair MG, Strasburg GM. Antioxidant and Cyclooxygenase Inhibitory Phenolic Compounds from Ocimum sanctum Linn. Phytomedicine. Mar2000;7(1):7-13. Lamaison JL, et al. Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv. 1991;66(7):185-8. Ponce MM, Navarro AI, Martinez GMN, et al. In vitro effect against Giardia of 14 plant extracts. Rev Invest Clin 1994;46:343–7 [in Spanish]. Stiles JC, Sparks W, Ronzio RA. The inhibition of Candida albicans by oregano. J Applied Nutr 1995;47:96–102. Tantaoui EA, Beraoud L. Inhibition of growth and aflatoxin production in Aspergillus parasiticus by essential oils of selected plant materials. J Environ Pathol Toxicol Oncol 1994;13:67–72. ImmunEnhancer AG (Larch tree Arabinogalactan) Corado J, et al. Impairment of Natural Killer (NK) Cytotoxic Activity in Hepatitis C Virus (HCV) Infection. Exp Immunol. 1997;109:451-457. Currier NL, Lejtenyi D, Miller SC. Effect over time of in-vivo administration of the polysaccharide arabinogalactan on immune and hemopoietic cell lineages in murine spleen and bone marrow. Phytomedicine. 2003 Mar;10(2-3):145-53. PMID: 12725568 Egert D, et al. Studies on Antigen Specificity of Immunoreactive Arabinogalactan Proteins Extracted from Baptisia tinctoria and Echinacea purpurea. Planta Med. 1992;58:163-165. Gonda R, et al. Arabinogalactan Core Structure and Immunological Activities of Ukonan C, An Acidic Polysaccharide from the Rhizome of Curcuma longa. Biol Pharm Bull. 1993;16:235-238. Hagmar B, et al. Arabinogalactan Blockade of Experimental Metastases to Liver by Murine Hepatoma. Invasion Metastasis. 1991;11:348-355. Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev. 1999 Apr;4(2):96-103. Review. PMID: 10231609 Kim LS, Waters RF, Burkholder PM. Immunological activity of larch arabinogalactan and Echinacea: a preliminary, randomized, double-blind, placebo-controlled trial. Altern Med Rev. 2002 Apr;7(2):138-49. PMID: 11991793 Levine PH, et al. Dysfunction of Natural Killer Activity in a Family With Chronic Fatigue Syndrome. Clin Immunol Immunopathol. 1998;88:96-104. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr. 2001 Aug;20(4):279-85. PMID: 11506055 Rolfe RD. The Role of Probiotic Cultures in the Control of Gastrointestinal Health. J Nutr. Feb2000;130(2S Suppl):396S-402S. Salyers AA, Vercellotti JR, West SE, Wilkins TD. Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon. Appl Environ Microbiol. 1977 Feb;33(2):319-22. PMID: 848954 Uchida A. Therapy of Chronic Fatigue Syndrome. Nippon Rinsho. 1992;50:2679-2683.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=987) Melatonin and 5-HTP 60ct - New from Kal
Date:
November 18, 2005 09:13 AM
Melatonin and 5-HTP the Ultimate Combo5-Htp Serotonin Melatonin Equals Relaxed and Refreshed Sleep
Supplement Facts Enhance your life with a more sound (deep) sleep every night. Other Sleep Aids like Melatonin from Kal Brand
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=945) Benefits of Alpha Lipoic Acid
Date:
October 13, 2005 05:08 PM
Benefits of Alpha Lipoic Acid
Alpha-lipoic Acid––the "Ideal Antioxidant"
The antioxidant potential of a substance is based on a number of criteria, including: The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.
As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3 DHLA-regenerates vitamin C, vitamin E and glutathione Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants. DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7 Alpha-lipoic Acid and Blood Sugar Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10 Scientific References 1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50. 2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63. 3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31. 4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21. 5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561. 6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637. 7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87. 8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4. 9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14. 10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=840) Benefits of Total Daily Formula
Date:
October 13, 2005 04:45 PM
Benefits of Total Daily Formula All fruits and vegetables contain carotenes, the plant pigments responsible for the rich variety of colors we enjoy in the natural world. Beta carotene is the most familiar member of the carotene family. But beta carotene never exists by itself; it is always found with other carotenes in foods. We need more than just beta carotene alone. Carotenes are powerful antioxidants, which means they help reduce the body's free radical burden. Research suggests that carotenes work as a team to keep us healthy.5 Total Daily Formula provides beta carotene, alpha carotene, lutein, lycopene, zeaxanthin and cryptoxanthin from natural sources such as algal extracts, carrot oil, marigold and tomatoes (Caromix®). Total Daily Formula uses only corn-free vitamin C (ascorbic acid). The full daily intake of 6 tablets provides an exceptionally generous 800 mg of vitamin C. Total Daily Formula supplies ample amounts of all essential B vitamins. Vitamin B3 is given as niacin plus an extra helping of niacinamide, the non-flush form of this important vitamin. The body uses pantothenic acid (vitamin B5) to deal with stress, so the formula provides 150 mg, which is 15 times the RDA. Vitamin B6 is another B vitamin people may run short of, so 60 mg -- 30 times the RDA -- is supplied. The formula contains 800 mcg of folic acid, the vitamin now recognized by the FDA as essential for prevention of neural tube defects in unborn babies. Folic acid also helps prevent accumulation in the body of homocysteine, a metabolite of the amino acid methionine.6 A high blood homocysteine level is now considered to be a risk factor for heart disease.7 Flavonoids, also known as "bioflavonoids." are plant pigments widely distributed throughout the plant kingdom.8 Previously known as "Vitamin P," because they help reduce capillary permeability (leakiness) flavonoids are now regarded as "semi-essential" non-vitamin nutrients that benefit health in a variety of ways.9 In addition to maintaining the structure of blood vessels, flavonoids function as versatile antioxidants. Flavonoids protect vitamin C from destruction by free-radicals, helping to preserve the body's vitamin C supply.10 Total Daily Formula provides 100 mg of pure flavonoids from 112 mg of citrus extract. Three superior sources of Calcium Total Daily Formula contains three of the best absorbed and most effective forms of calcium available. MCHC (microcrystalline Hydroxyapatite concentrate) is a naturally-derived compound composed of calcium, plus all the minerals and organic factors in living bone tissue. MCHC has been clinically shown to benefit bone health.11 Calcium citrate malate is a very well-absorbed form of supplemental calcium shown in recent research to be helpful for postmenopausal women.12,13 Calcium glycinate is chelated with the amino acid glycine, one of the most efficient mineral carriers for effective absorption.14,15 Magnesium is essential for strong bones and healthy hearts. This versatile mineral also regulates nerve function, keeps muscles relaxed and coordinates activity of over 300 enzymes in the body.16 Total Daily Formula contains 100 percent magnesium glycinate for exceptional absorption and gentleness on the intestinal tract.17 Magnesium glycinate has been clinically tested on people with severe malabsorption with excellent results.18 Total Daily Formula provides - in addition to zinc, chromium, selenium and iodine - vanadium and molybdenum. Vanadium helps maintain normal blood sugar.19 Molybdenum works as a co-factor for enzymes that help detoxify and eliminate foreign substances from the body.20 Bioperine® for Enhanced Absorption Bioperine® is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine®. 21 Betaine HCL - supplies HCL (hydrochloric acid) to assist digestion. All natural tablet coating made of vegetable concentrate and beta carotene.
Scientific References 2. Morgan, K.J. et. al. Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition. 1985;4:195-206. 3. Lakschmanan, F.L., Rao, R.B., Kim, W.W., Kelsay, J.L. Magnesium intakes, balances and blood levels of adults consuming self-selected diets. American Journal of Clinical Nutrition 1984;40:1380-89. 4. Mertz, W. The Essential Trace Elements. Fed. Proc. 1970;29:1482. 5. Perry, G. Byers, T. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Annu. Rev. Nutr. 1992;12:139-59. 6. Landgren, F., et. al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Int Med 1995;237:381-88. 7. Clarke, R., et. al. Hyperhomocysteinemia: an independent risk factor for vascular disease. New Eng J Med 1991;324:1149-55. 8. Havsteen, B. Flavonoids, a class of natural compounds of high pharmacological potency. Biochemical Pharmacology 32(7):1141-48. 9. Middleton, E. The flavonoids. TIPS 1984; 5:335-38. 10. Roger, C.R. The nutritional incidence of flavonoids: some physiological and metabolic considerations. Experientia 44(9):725-804. 11. Dixon, A. St. J. Non-hormonal treatment of osteoporosis. British Medical Journal 1983;286(6370):999-1000. 12. Smith, K.T. et. al. Calcium Absorption from a new calcium delivery system (CCM). Calcif Tissue Int 1987;41:351-352. 13. Dawson-Hughes, B. et. al. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. New England Journal of Medicine 1990 Sep 27;323(13):878-883. 14. Albion Research Notes Vol. 4, No. 1, ©Albion Laboratories Jan,1995. 15. Ashmead, H.D. Intestinal Absorption of Metal Ions and Chelate, Springfield: Charles C Thomas, ©1985. 16. Wester, P.O., Dyckner, T. The importance of the magnesium ion. Magnesium deficiency-symptomatology and occurrence. Acta Med Scand 1992; (Suppl) 661:3-4. 17. Albion Research Notes Vol. 3, No. 1, ©Albion Laboratories, Feb 1994. 18. Schutte, S., et. al. Bioavailability of Mg diglycinate vs MgO in patients with ileal resections. Abstract 115, AJCN 1992;56(4). 19. Cohen, N. et. al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin Invest 1995; 95:2501-09. 20. Sardesi, V.M. Molybdenum: An essential trace mineral element. Nutr Clin Pract 1993; 8:277-81. 21. Bioperine® - Nature's Bioavailability Enhancing Thermo-nutrient. Executive Summary' 1996; Sabinsa Corporation, Piscataway, N.J.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=839) Cinnamon may control sugar levels...
Date:
July 08, 2005 10:48 AM
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=565) NEW PRODUCT ANNOUNCEMENT
Date:
July 05, 2005 06:29 PM
The Most Comprehensive Antioxidant Formula Available!
Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
gamma-Vitamin E Complex 500 mg
Quercetin 100 mg
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=548) Quercetin and Bromelain - for better health.
Date:
July 04, 2005 10:28 AM
Benefits Down-regulates the Body’s Response to Environmental Challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10 Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges. Maintains Tissue Comfort by Regulating Enzymes* Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures. Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13 Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16 Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of free-radicals such as Hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19 Helps Maintain Normal Blood Viscosity* Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.* Bromelain May Enhance Quercetin Absorption In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.
Scientific References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=546) 5-HTP - The Science of Sleep
Date:
June 29, 2005 02:22 PM
Sleep is especially important in today’s world. It’s the time when your body repairs, rebuilds and replenishes the tissues and compounds that have been damaged or depleted by the demands of your life. But when there is too much stress, imbalances occur that can keep you from getting enough sleep. Source Naturals, the science company, introduces 5-HTP to help promote healthy sleep cycles. 5-HTP, or L-5-Hydroxytryptophan, is created when the tryptophan in your body is converted into serotonin. 5-HTP can cross the blood-brain barrier and is associated with increasing active serotonin levels as well as serotonin production. And those increased serotonin levels are associated with healthy sleep regulation, increased melatonin production for 24-hour sleep cycle regulation, mood regulation, and appetite control. Source Natural’s 5-HTP capsules are safely and naturally derived from Griffonia simplicifolia seeds. How 5-HTP Works 5-HTP works because it supports your body’s balanced production of two important sleep regulating hormones, serotonin and melatonin. Serotonin is a neurotransmitter that helps regulate sleep, moods and appetite. But you need adequate serotonin levels to maintain this balance. 5-HTP is the serotonin precursor that is formed when tryptophan is converted into serotonin in your body. In clinical research, 5-HTP increased the amount and availability of serotonin produced by the body. It is able to cross the blood brain–barrier to increase both serotonin levels and serotonin production in your brain so you can regain a healthy balance when you are sleeping, feeling emotions, or eating. Eventually, the serotonin in your body is converted into melatonin, the hormone that helps regulate healthy 24-hour sleep cycles known as circadian rhythms. Aging and various forms of physical or emotional stress can decrease your melatonin levels and disrupt your sleep cycle. Fortunately, that balance can be regained. When 5-HTP increases serotonin production, melatonin production is also increased, which can help you regain a healthy circadian rhythm. Naturally Promoting Healthy Sleep Source Naturals 5-HTP is safely derived from Griffonia simplicifolia seeds and is available in 50 and 100 mg potencies. Innovative natural products, such as 5-HTP, are part of a new paradigm in health care. You can join this revolution in preventive wellness, long before it becomes mainstream, by taking charge of your health with products that are only available at natural food and nutrition outlets. Support your healthy moods, eating habits and sleep cycles with the science of Source Naturals 5-HTP today. Three Tips for a Healthy Sleep Cycle
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=532) GREEN COFFEE EXTRACT - Powerful Natural Antioxidant
Date:
June 29, 2005 11:06 AM
According to the National Coffee Association’s 2001 National Coffee Drinking Trends survey, 52 percent, or 107 million, U.S. adults drink coffee each day. Although you may already enjoy coffee as your favorite way to begin the morning, new studies are revealing its impressive health benefits. GREEN COFFEE EXTRACT (GCA®) is a newly discovered powerful antioxidant that helps protect against oxidative stress caused by free radicals - a major cause of accelerated aging. Source Naturals GREEN COFFEE EXTRACT (GCA®) is a patent-pending, all-natural green coffee bean extract derived from raw, unroasted coffee beans. It is high in chlorogenic and caffeic acids, two primary compounds responsible for its antioxidant activity. GREEN COFFEE EXTRACT is naturally low in caffeine and contains at least 65 percent total polyphenol antioxidants. The Coffee Story The history of coffee dates back more than a thousand years. Originally, coffee beans were used as food. East African tribes would grind the coffee berries together, mixing the results into a paste with animal fat. Later, around 1000 AD, Ethiopians made a type of wine from coffee berries, fermenting the dried beans in water. Coffee also grew naturally on the Arabian Peninsula where it was first developed into a hot drink. Despite decades of research on coffee and caffeine, there are many misconceptions about the potential health risks associated with coffee, while many of the beneficial aspects have gone unnoticed. Polyphenols: Powerful Antioxidants Phenolic compounds, or polyphenols, are a widespread family of compounds found in all plants including grapes, coffee and tea. They possess outstanding antioxidant and free radical scavenging properties, which may help defend cells and protect the body against the effects of aging. The high antioxidant activity observed in research on coffee is believed to be mostly due to the phenolic acids. GREEN COFFEE EXTRACT contains a number of polyphenols called Hydroxycinnamic acids, with the two most prominent being chlorogenic and caffeic acids. Caffeic acid is the most abundant phenolic compound in coffee. In vitro and in vivo studies show that these acids protect against low-density lipoprotein (LDL) oxidation and lipid peroxidation. Glucose Metabolism There is accumulating evidence that certain dietary polyphenols, such as chlorogenic acid, may have biological effects in the small intestine that alter patterns of glucose uptake. Chlorogenic acid has been shown to inhibit glucose 6 phosphate (Glc-6-Pase) activity. Glc-6-Pase is an enzyme that has a key role in regulating glucose metabolism. An in vivo study on rats demonstrated that chlorogenic acid improved glucose tolerance. Natural Wellness Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN COFFEE EXTRACT.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=525) Promilin Fenugreek Extract - Supports Healthy Blood Sugar Levels
Date:
June 28, 2005 10:44 AM
.. Your body’s ability to manage blood sugar may well be the single most crucial factor affecting your health and longevity, and the one most affected by diet and lifestyle. But today’s high-glycemic carbs and sugar-laden foods — combined with lack of exercise — are creating a serious challenge to your body’s intricate glucose/insulin regulatory system. The resulting cellular stress and deterioration have serious repercussions for both your mind and body. To promote optimal wellness through healthy sugar metabolism, Source Naturals formulated PROMILIN™ FENUGREEK EXTRACT, a potent extract from the highly valued herb fenugreek, into an advanced nutritional supplement designed to assist insulin production and support healthy glucose levels. As a complement to your diet, Source Naturals PROMILIN™ FENUGREEK EXTRACT is an excellent strategy to improve blood sugar levels, and consequently, quality of life. The basis of Source Naturals PROMILIN™ FENUGREEK EXTRACT is fenugreek (Trigonella foenum-graecum), a respected culinary and medicinal herb used throughout history. One of the formula’s fenugreek extracts is rich in galactomannan, a mucilaginous fiber that may benefit the bowel. The other extract is Promilin, a patent-pending complex of bioactive amino acids standardized to contain 20% 4-Hydroxyisoleucine. This extraordinary amino acid derivative assists the pancreas in production of insulin. Several studies with animals and with human cell cultures demonstrate this extract’s positive effect on reducing post-meal glucose levels — with little or no increase in blood insulin concentrations — a clear indicator of improved insulin sensitivity. Sports Nutrition and Blood Sugar Athletic energy and endurance depend on the ability of muscles to recover from exercise. Because PROMILIN promotes utilization of glucose and insulin by the the body’s muscle cells, “weekend warriors” will feel less fatigue on Monday morning. In a clinical study, PROMILIN increased glycogen re-synthesis by 63% over carbohydrate alone. This is the rate at which post-exercise muscle glycogen (energy) is restored. PROMILIN may also play a role in weight management because it helps your body metabolize carbohydrates more efficiently. And the less time glucose spends in your bloodstream, the less chance it will be converted into fat. By supporting glucose metabolism, Source Naturals PROMILIN™ FENUGREEK EXTRACT may help protect against a harmful process called glycation, where excess glucose reacts with amino acids to form crosslinked sugardamaged proteins that damage the linings of blood vessels, the lens of the eye, and the myelin sheath that insulates brain cells.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=513) REFERENCES
Date:
June 25, 2005 08:13 PM
REFERENCES 1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-Hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=507) MECHANISMS OF CHITOSAN FAT- BINDING
Date:
June 25, 2005 08:02 PM
MECHANISMS OF CHITOSAN FAT- BINDING The exact way(s) that Chitosan prevents fat absorbtion is not fully understood but a number of experimental observations support two basic mechanisms. The first mechanism involves the attraction of opposite charges which can be compared to the attraction of opposite magnetic poles. The second entrapment mechanism can be compared to the effect of a net. In the first mechanism the positive charges on chitosan attract the negatively charged fatty acids and bile acids binding them to the indigestible chitosan fiber. This mechanism can explain why chitosan reduces LDL cholesterol levels. Our bodies make bile acids in the liver using the cholesterol from LDL. When chitosan binds bile acids it increases the rate of LDL loss thus improving the LDL to HDL ratio. If enough bile acids are bound, the fats are not solublized, which prevents their digestion and absorption. The second mechanism (figure 2) describes a netting effect of chitosan fiber. In this model the Chitosan wraps around fat droplets and prevents their being attacked and digested by lipid enzymes. Fats unprotected by Chitosan are digested and absorbed. The “netting” mechanism has been seen to operate in vivo. 108 Substances that Enhance the Action of Chitosan Fibers can be likened to a tangled-up chain. Fibers must “unravel” in order for them to be of maximum benefit to us. “Unraveling” is especially critical for chitosan because each link has a hook on which to attach lipids. Chitosan can absorb an average of 4 to 5 times its weight in lipids. Reports of numbers above and below this range have also been reported and may well reflect the rate or extent of unraveling that had taken place. Fiber formulations can be prepared that unravel rapidly and swell quickly. These highly effective formulations are called superabsorbants. When certain substances are added to chitosan, its remarkable fat-binding ability can be significantly enhanced. Ascorbic Acid D-Ascorbic acid (erythorbic acid) and L-ascorbic acid are C-vitamins which enhance chitosan’s ability to bind lipids. Combining chitosan with ascorbic acid results in even less fat absorption and greater fecal fat losses.77,108 In one study the addition of ascorbic acid to a chitosan enriched diet increased fecal fat losses by 87 percent and decreased fat absorption by over 50 percent.77 Cholesterol oxides cause lesions in artery walls which predispose blood vessels to collect plaque. These dietary cholesterol oxides profoundly influence the initiation of heart disease.Free radicals can also contribute to the formation of cholesterol oxides which are even more likely to damage the heart. Cholesterol oxides have been found in deep-fried foods, powdered eggs, processed meats and in human blood itself. Consequently, taking antioxidants like ascorbic acid is vital to protect against the cellular damage this type of free radical causes.112 Citric Acid In feeding experiments with animals, adding citric acid to a chitosan enriched diet resulted in a decreased feed consumption.77 The most likely explanation for this effect is that the citric acid may be enhancing the swelling action of chitosan leading to a sense of fullness, producing satiety and appetite suppression. Indoles Indoles are remarkable phytochemicals which have the ability to selectively activate certain Mixed Function Oxidases (MFOs).113 These MFO’s help balance estrogen metabolism and prepare dietary toxins for elimination before they are absorbed. The presence of fiber in the intestines provides a bulk agent to carry the metabolized toxins out of the body. Chelat ed Minerals The very best approach to weight loss is to nutritionally augment food choices with nutrient supplementation. Certain biochemical compounds are essential to promoting vigor during the process of thermogenesis. Chelated minerals act to bolster, support and protect the organ systems of the body.114,115 For example, when fat is burned, heat and energy are released. If a lack of certain minerals exists, energy levels will drop. Minerals help to transport needed nutrients to depleted areas of the body, thereby stemming off the fatigue we so often experience after eating a fatty meal. Even more importantly, free radicals are released whenever fat is consumed and burned and the presence of chelated minerals helps to expedite the removal of these metabolites and facilitate the availability of fuel for energy. Essential Fatty Acids Prostaglandins control and balance many body functions. The dietary building blocks for making prostaglandins are the essential fatty acids (EFAs). The role of prostaglandins in weight loss has been extensively discussed in a recent review.116 EFAs exert profound lipid-lowering effects.They reduce the synthesis of triglycerides and very low density lipoproteins (bad cholesterol) in the liver. EFA supplementation coupled with a low-cholesterol, low-saturated fat in diet produces a complementary effect in lowering serum lipid levels.117 Garcinia Cambogia ( Hydroxy Cit ric Acid) Garcinia Cambogia contains Hydroxycitric acid (HCA). This form of citric acid inhibits the liver’s ability to make fats out of carbohydrates.118 Carbohydrates are converted to glycogen stores, not fat stores, giving the body a better energy reserve and an increase in stamina.119 Ephedra And Thermogenisis Thermogenesis means “creating heat.” This is one of the ways our bodies have of burning off excess calories and maintaining a constant weight.120 This is an area of weight management research that is being intensely studied. When we repeatedly yo-yo diet or abuse ourselves by eating too much, our thermogenic ability may be reduced. Numerous animal and human studies have confirmed the benefits of ephedra and methylxanthines in inducing weight loss and restoring thermogenic responsiveness.43,44,121
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=502) RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
Date:
June 24, 2005 05:34 PM
The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers. Bio-Aligned Antioxidant Support RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA. Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, Hydroxyl, and superoxide radicals, and singlet oxygen. Healthy Heart Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support. Nourishing the Brain Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support. Liver Support Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E. Immune Defense The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense. Skin & Connective Tissue Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C. Clear Vision Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes. Energy Generation Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration. DNA Protection DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose. Living Longer, Living Better Strategies for Wellness
Wellness Revolution Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today. References Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868. Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=422) Anti-Aging Nutrients
Date:
June 18, 2005 09:07 AM
Anti-Aging Nutrients by Edward C. Wallace, DC, ND Energy Times, February 3, 2000 What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful, easy feeling. How Do We Age? Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD. The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress. Programmed Cell Theory In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing. Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging. Free Radical/Oxidative Stress Theory The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster. DNA Repair Theory Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die. What Can We Do? The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging. In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function." Antioxidant Protection Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit. Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency. In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly. Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens. Nutrition Deficiencies A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15). When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993). A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage. Longevity Diets A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460). Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers (Epidemiology 3[5], 1992: 389-391). Staying Alive Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines. Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63). In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat. Longevity and Exercise Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer. Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams. The Treadmill of Life The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying (JAMA 273 [14], April 12, 1995: 1093-1098). Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk. Longevity Supplementation Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called Hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways. Toning Down Enzymes Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain Hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154). In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies. The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552). Vitamins E & C A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial. Chronological Age Vs.Biological Age Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C. Similar Relationship A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons. The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988). Carotenoids When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene. Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119[1], Jan. 1989: 112-115). Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered. Flavonoids Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system. Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54). Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds. Amino Acid Health Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too. Attitude & Behavior Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15). In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14). Longevity at Last While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of longer life. And by staying healthier, your old age will be more enjoyable, too.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=377) Enhancer for Youthful Vitality
Date:
June 16, 2005 08:20 PM
NEW PRODUCT ANNOUNCEMENT Enhancer for Youthful Vitality
Five tablets contain: Suggested Use: 5 tablets before exercise and/or at bedtime with plenty of water at least two hours after the last meal. Discontinue use or reduce dosage if any of the following symptoms are present: nausea, excessive salivation, vomiting, diarrhea, muscle spasms, cramps, excessive urination, insomnia, headache, cardiac arrhythmias, high blood pressure, or changes in mood or emotional balance.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=369) Move it and Lose it! Burn off body fat!
Date:
June 14, 2005 12:04 PM
Move it and Lose it! Burn off body fat! by Mimi Facher Energy Times, June 1, 1997 So you're feeling a little blah, a little overweight, and you're looking to drop a few of those winter pounds gained during the colder months. Maybe you've dabbled with diets and jogged around the neighborhood a few times but you're still packing unsightly bulges. If so, you may be considering the idea of turning to supplements to help you drop those pounds. Well, two types of diet supplements now generally available, combined with a diet and exercise program, may be able to help you trim those stubborn pounds. The first type of supplement, called metabolic optimizers, which include ephedra, caffeine and salicin (derived from willow bark), boost your metabolic rate, causing your body to burn calories faster. The second class, lipotropic substances, aid the body in fat mobilization, causing greater utilization of stored fat. These products include chromium, carnitine and Hydroxycitric acid (HCA). Both classes of supplements have been around in various forms for quite a while but are now enjoying greater popularity among dieters. Trying to cope with a weight problem is a dilemma expanding throughout modern society. According to a 1995 Harris poll, nearly 75% of Americans are overweight. Although it's well known that the way to lose weight is to expend more calories than you take in, supplements may be able to help you burn off extra calories. Thermogenesis and You Metabolic optimizers are supposed to aid weight loss through a process called thermogenesis. Thermogenesis is a natural process in which fat is burned to produce body heat. Fat that isn't burned is stored on the hips, thighs, stomach, etc. Thermogenic agents are designed to counteract your body's fat storage mechanisms by causing your body to maintain a higher metabolic rate-turning your internal thermostat up to burn fat faster. The thermogenic process can be jump-started by a number of factors including cold, exercise, certain dietary nutrients and metabolic optimizers. Ephedra The ephedra herb, also known as ma huang is one of nature's earliest medicines, known for over 5000 years to the Chinese, who used it to relieve allergies, coughing, wheezing and cold and flu symptoms. In the US, ephedra has been available since the 1800s. The ingredients in ephedra include the alkaloids ephedrine, pseudoephedrine and norephedrine. Concentrated forms of these substances are used in today's over-the-counter cold, allergy and asthma relief formulas. Ma huang's effectiveness as a weight loss aid is tied to its appetite suppressant and stimulant properties. By speeding up action of the thyroid gland, the ephedrine found in the herb acts a thermogenic agent, boosting the rate at which the body metabolizes fat and promoting weight loss. According to Mark Blumenthal, Executive Director of the American Botanical Council, "When used as part of a total package that includes diet modification and exercise, ma huang can be highly effective in the short run because it increases the speed of the body's metabolism and suppresses appetite." Because of their strong stimulant effect, ephedra and its derivatives have engendered some controversy. However, in its long history, billions of doses of ephedra have been consumed without problem. But ephedra supplements should only be used as directed on product labels. People with cardiovascular problems, diabetes, thyroid or prostate dysfunction, high blood pressure and those taking MAO inhibitors, pregnant or nursing should avoid this herb. Salicin Burns Fat Salicin, a substance derived from willow bark-which is also the original source for aspirin, a related compound-can boost the burning of fat when combined with ephedra. An animal study in the American Journal of Clinical Nutrition found that while ephedra boosted calorie burning by almost 10%, when ephedra was combined with aspirin, extra calorie burning just about doubled. Another study in the Internatioanl Journal of Obesity showed that when overweight women took aspirin and ephedrine during a meal, their bodies burned off more calories than normal. (Eating a meal produces a thermogenic effect as your body expends energy in digestion. That's why dieters are told not to skip meals. Skipping meals lowers your metabolic rate, decreasing your calorie expenditure.) Similar studies also show that caffeine, the stimulant that gives coffee its eye-opening kick, can also boost ephedra's thermogenic properties. But before using these combinations check with a health practitioner knowledgeable about nutrition. Aspirin or salicin may cause stomach upset in some people (although salicin is generally tolerated well.) Carnitine: Lipotropic Amino Acid To get carnitine into your system, you don't have to take it as a supplement. Your body already makes this vitamin-like substance. However, your body doesn't make that much. And it is said to be especially low in people with heart disease. This non-essential amino acid (said to be non-essential because human bodies produce it) is a key ingredient in the formation of mitochondria membranes. Mitochondria are tiny structures in your cells that burn fats for energy. Consequently, sufficient carnitine is necessary for the movement of fat into the mitochondria where it is consumed. When not enough carnitine is present, the breakdown of long chain fatty acids slows down. Said to improve the recovery rate for athletes (it may limit the production of lactic acid, a waste product in muscle tissue), carnitine can also lower cholesterol levels, boost levels of HDL (the good cholesterol) and decrease serum triglycerides (blood fats linked to heart disease). Not bad for a nutrient that coaxes fat into those teeny, ceullular, mitochondrial furnaces. Go for the Chrome Chromium-based supplements work as lipotropic agents by aiding insulin use in the body. This essential trace mineral is required for normal protein, fat, and carbohydrate metabolism. According to Dr. Michael Janson, author of The Vitamin Revolution in Healthcare and President of the American Preventive Medical Association (APMA), "Chromium is important for proper insulin activity. Insulin moves sugar into the muscle cells, where it is burned off as energy. Chromium improves the activity of insulin, and since insulin causes fat deposition, less of it means less fat deposition." Chromium has also been shown to build muscle tissue and to reduce LDL cholesterol, which has been linked to heart disease. Although the body's minimum requirement is low, the American diet tends to be deficient in chromium, in part because the mineral can be difficult for the body to absorb. The fact that, in nature, chromium is most powerfully concentrated in brewer's yeast, wheat germ and liver-items most Americans rarely eat-probably hasn't helped either. Other natural sources of chromium include whole grains, molasses and beef. But it is estimated that 50% of Americans are chromium deficient. An early study found that overweight adults taking a chromium supplement lost an average of 22% body fat, while maintaining or gaining lean body mass. In another study, athletes consuming 200 mcg. of chromium a day showed an average loss of 7.5 lbs. of body fat after six weeks, without a corresponding loss of muscle tisue. Overall, although some studies question chromium's precise effects, many experts are optimistic about this substance because of its relationship to insulin in the body's metabolism. Hydroxycitric Acid (HCA) Another possible addition to the dieter's arsenal is HCA. In nature, HCA appears chiefly in a fruit called garcinia cambogia (sometimes also called Malabar tamarind or brindall berry), a citrus plant found primarily in Asia, where the rind is often used as a flavoring agent. HCA works by inhibiting the enzyme in the body responsible for converting carbohydrates into fat. HCA causes calories to be burned in an energy cycle similar to thermogenesis and acts as somewhat of an appetite suppressant. HCA is also said to have a role in reducing triglycerides and LDL cholesterol levels. Several animal studies have shown that HCA caused significant weight loss without a reduction in lean body mass. In other words, the pounds that came off came out of fat stores, and not out of energy or muscle reserves. This means that HCA takes off not just weight but body fat, making it a potentially effective tool against weight regain. Dr. Elson Haas, director of the Preventive Medical Center of Marin in San Rafael, CA, and author of Staying Healthy With Nutrition: The Complete Guide to Diet and Nutritional Medicine, believes that HCA can be a helpful aid for dieters when used in combination with eating habit changes and exercise. He recommends an HCA and chromium blend for optimum appetite suppression. "This combination can keep the appetite down and reduce sugar cravings," he says. Although human research data on HCA is still in the preliminary stages, the animal study results are positive, and the supplement seems to have minimal side effects in most people. Some Overall Recommendations You are likely to lose weight faster if you eat sensibly. This means avoiding foods high in fat or sugar (which are the most likely to add to stored body fat), but it doesn't mean starving yourself. A sensible balanced diet, along with moderate exercise, is still the best prescription for weight loss. As Dr. Haas puts it, "I'm a firm believer in diet and exercise. Using supplements responsibly can help you to lose weight provided they're combined with dietary changes and exercise. They won't work if you don't change anything." No one is suggesting that dietary supplements are a miracle cure for being overweight-as always in self-health care, there are no magic wands. But, used as directed and combined with a good diet and exercise plan, you could find that these supplements might help you work your way to a slimmer you. Mimi Facher is a freelance writer who has contributed to Prevention, Cosmopolitan and Self.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=349) Winter Survival Kit
Date:
June 13, 2005 07:35 PM
Winter Survival Kit by Joanne Gallo Energy Times, February 4, 2000 Now that the flesh-baring season is but a distant memory, skin care may have dropped off your list of priorities. But unless you're planning on hibernating until May, Old Man Winter can play a cruel joke on your smooth, glowing complexion-causing cumulative damage not easily remedied. Defend yourself with our survival kit and keep the harsh elements from wreaking havoc on your outer sheath. Winter Blast Frigid temperatures and blustery winds take their toll on everyone's skin, whether it's normal, oily or dry. Cold dry air, combined with arid indoor heat, results in less natural sebum (oil) production. This oil acts as a protective barrier that helps hold moisture on the surface of the skin; hence less sebum leads to a rough and dry exterior. Icy winds can also cause redness as the stress induces tiny capillaries just underneath the skin's surface to burst. So the first order of business for winter skincare is preserving your skin's moisture. Along with external methods of bundling up all exposed areas, dietary habits can help preserve moisture internally. Skincare consultant Lynn J. Parentini, author of The Joy of Healthy Skin: A Lifetime Guide to Beautiful, Problem-Free Skin (Prentice Hall), suggests reducing your intake of coffee and tea, which act as diuretics; eating lots of fresh fruits and vegetables, which contain natural, vitamin-rich moisture; and increasing the amount of water you drink (those daily recommended eight glasses of water are even more important in winter). A Cleansing Experience Bathing can strip skin of its natural oils, so you should be careful of washing with overdrying soaps. Avoid deodorant soaps with harsh detergents which can irritate the skin, and look for milder soaps with moisturizers or a skin-softening shower gel. Neutrogena Rainbath Shower & Bath Gels gently cleanse and condition skin with a rich, full lather that won't leave a residue. Showers tend to be less drying than baths, but if you prefer soaking in a tub you can use bath oil to lubricate the skin. Also avoid very hot showers and baths as they can pull moisture out of the body. For extremely dry and sensitive skin, shower at night and follow with a rich moisturizer. Skin then can replenish its protective oils before the morning's icy blast. Skin Savers Now's the time to use a heavier cream moisturizer to counteract all these dehydrating forces, so finding the right one is imperative. In simpler times, choosing a body moisturizer came down to which one possessed the most pleasing smell. Today, lotions are formulated with nutrients and natural ingredients for powerful, soothing benefits. • CAMOCARE Soothing Cream contains patented Camillosan Camomile, a natural anti-inflammatory. This thick, therapeutic cream is great for dry patches on hands or elbows. Face the Season Faces need extra-special protection during winter, as moisturizers do double duty to fight the elements and aging. Many formulas contain alpha (AHA) and beta Hydroxy acids: gentle exfoliants that slough off the top layer of dead skin cells to allow younger, smoother-looking skin to emerge. • Oil of Olay's Age Defying Series: Protective Renewal Lotion contains moisturizers, a beta-Hydroxy complex, vitamin E and SPF 15. • Neutrogena Healthy Skin Face Lotion is formulated with alpha-Hydroxy acids to ease lines, blotches and discoloration; vitamin A and pro-vitamin B5 to increase firmness and moisture levels; and antioxidant vitamins C and E to fight free radical damage and protect new skin. Sun Damage So you think the sun is the least of your problems in the winter? Better reflect on that matter again. The general public has finally warmed up to wearing sunblock in the summer, but year-round protection against ultraviolet (UV) rays is crucial to avoid premature aging. There are two types of UV rays, UVA and UVB: the former are responsible for aging and the latter for burning. Although UVB rays produce a more blatant sign of skin damage, it is limited to the epidermis, or outer layer of the skin. UVA rays, on the other hand, don't cause any discomfort, but they penetrate deep to the dermis or second layer of skin. Researchers at the University of Pennsylvania Department of Dermatology have shown that chronic exposure to sunlight can cause holes and breaks in the elastin and collagen fibers that give the skin its shape, definition and supple quality. This damage is what is known as "photoaging." Severely photoaged skin appears dry, scaly, leathery, spotted and deeply wrinkled. While the burning UVB rays are most intense during the summer months, UVA rays are prevalent year-round. Their effect on the skin is cumulative, so that the more you're exposed the more likely your skin is to age prematurely. And as only 14% of Americans wear sunscreen year-round (according to the American Academy of Dermatology), most of us are getting more UVA exposure than we realize. " New clinical evidence proves that sun damages the skin much faster than previously thought," notes Zoe Draelos, MD, clinical associate professor of dermatology at Wake Forest University School of Medicine. "It only takes small amounts of sun exposure, such as walking to the car or to the mailbox, to start skin damage." And for those who engage in popular winter sports like skiing, UVA rays are even stronger at higher elevations. Sunblocks with high SPFs (sun protection factor) guard against UVB rays but they do not block against UVAs, so many sunscreen products do not sufficiently protect against the entire range of UVA rays. It is crucial, then, to look for products that guard against the entire spectrum of UVA/UVB rays. Sunblocks that contain zinc oxide, titanium dioxide or Parsol 1789 provide complete protection against aging and burning rays. Try Coppertone Shade UVA Guard SPF 30, Hawaiian Tropic 30 Plus Broad Spectrum Sunblock, L'Oreal Ombrelle Sunscreen Lotion or Spray in SPF 15, or PreSun Ultra SPF 30. Lip Tips Don't forget that the lips are particularly susceptible to sun damage too. In comparison to other facial skin, they have far fewer oil glands, no sweat glands, a much thinner protective outer layer and very few melanocytes, the cells that produce the protective pigment melanin. Accumulated sun exposure makes the lips less plump as UV rays damage their collagen and elastin fibers, resulting in rough spots, scaly patches or faded areas. Even if you wear lipstick on a regular basis, most do not contain the sunscreens and conditioners you can find in a lip balm. Blistex offers a wide range of lip care products, like their new Blistex Herbal Answer, which contains the conditioning qualities of five natural, herbal extracts: aloe, chamomile, avocado, jojoba and shea butter, plus SPF 15; Blistex Ultra Protection with SPF 30 has six protectants for advanced defense against cold, wind and sun; Blistex DCT (Daily Conditioning Treatment) with SPF 20 contains aloe, lanolin, cocoa butter, and vitamins A and E to help keep lips soft and supple. o
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=334) Defeat Depression
Date:
June 13, 2005 01:18 PM
Defeat Depression by Cal Orey Energy Times, August 2, 1999 Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery. More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering. Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame. According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life. The good news: Research shows that diet and lifestyle can lower your risk of depression. Birth of the Blues Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes. Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression. The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours. Plan B Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5). Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast. NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions." Moody Spotlight Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression. "SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York. Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e." (Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.) SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant. For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14). 5-HTP: Another popular supplement to boost mood and relieve depression is Hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand. "One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts. Herbal Relief St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that hypericum produced fewer side effects than conventional anti-depressants. Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers. "In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner. Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve." Amino Acid Help Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity. For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety. The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine. In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress. Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.) Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins. Depressive Smoking For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally. Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99). "Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers. If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=329) Nutrients for Longevity
Date:
June 10, 2005 09:59 PM
Nutrients for Longevity by Edward C. Wallace, ND, DC Energy Times, September 1, 1999 What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful easy feeling. How Do We Age Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD. The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress. Programmed Cell Theory In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing. Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging. Free Radical/Oxidative Stress Theory The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster. DNA Repair Theory Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die. What Can We Do The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging. In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function." Antioxidant Protection Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit. Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency. In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly. Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens. Nutrition Deficiencies A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15). When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993). A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage. Longevity Diets A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460) Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers. (Epidemiology 3[5], 1992: 389-391). Staying Alive Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines. Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects. (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63). In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat. Longevity and Exercise: Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer. Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams. The Treadmill of Life The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying. (JAMA 273 [14], April 12, 1995: 1093-1098). Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk. Longevity Supplementation Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called Hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways. Toning Down Enzymes Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain Hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154). In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies. The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552). Vitamins E & C A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial. Chronological Age Vs. Biological Age Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C. Similar Relationship A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons. The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988). Carotenoids When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene. Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119(1), Jan. 1989: 112-115). Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered. Flavonoids Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system. Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54). Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds. Amino Acid Health Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too. Attitude & Behavior Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15). In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14). Longevity at Last While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of living longer. An added benefit: By staying healthier, your old age won't only be longer, it will be more enjoyable, too. And, who knows, if you hang around long enough, taking your nutrients and getting a comfortable amount of consistent exercise, while meditating and refusing to succumb to stress, that magic bullet that will keep you alive for centuries may be discovered. Some day a new antioxidant or other substance may finally prove to provide the elusive fountain of youth. Stay tuned.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=283) Skin Eternal - Replenish Your Skin
Date:
June 06, 2005 08:45 AM
Source Naturals is proud to introduce our new SKIN ETERNAL Cosmetic Line. Our advanced skin care products recharge and revitalize your skin. Each product features scientifically advanced nutraceuticals: nutrients and botanicals with an inborn affinity for skin. You can nourish your skin with Source Naturals’ richly emollient SKIN ETERNAL CREAM smoothed under your eyes or on your neck. Or use our light, aqueous SKIN ETERNAL SERUM. Both products gently addresses imbalances and infuse skin with visible radiance. For a luxuriant, moisturizing bath, simply add SKIN ETERNAL BATH OIL under warm running water. Whatever your individual preference, Source Naturals has a SKIN ETERNAL product that will leave your skin looking refreshed and energized. Now available from Source Naturals®: a variety of elegant cosmetics to moisturize, smooth and tone your skin. Your skin is a reflection of your health and well-being. To attain skin that looks truly alive, energized and refreshed, we believe a holistic approach is necessary. This includes nourishing your body with fresh, organic foods, exercising every day to motivate your mind and spirit, and eliminating unhealthy lifestyle choices. As part of this holistic approach, the Skin Eternal™ cosmetic line feeds your skin cells with scientifically advanced nutraceuticals: nutrients and botanicals with an inborn affinity for skin. SKIN ETERNAL™ CREAM Apply this rich and luxurious blend under and around your eyes or massage it with upward strokes onto your neck—your skin will immediately feel the difference! SKIN ETERNAL CREAM features nutrients, natural oils and plant extracts. Included are alpha lipoic acid, biotin, CoQ10, DMAE, jojoba oil, MSM, squalane, tocotrienols, and vitamin C-ester, as well as extracts of grape seed, ginkgo, ginseng, green tea, sage, marigold, and grapefruit seed. SKIN ETERNAL™ SERUM SKIN ETERNAL SERUM is an aqueous moisturizing serum that contains a rich blend of nutrients and plant extracts. It is easily absorbed, and immediately makes skin feel softer and replenished. SKIN ETERNAL SERUM is lightly scented with pure lavender and lemon oils, and contains nutrients and herbs unavailable in other topical preparations. These include aloe vera, alpha lipoic acid, biotin, CoQ10, DMAE, MSM, vitamins A, C-ester, D-3 and E, and chamomile. Source Naturals also offers SKIN ETERNAL DMAE SERUM. SKIN ETERNAL™ BATH OIL OUR NEW SKIN ETERNAL BATH OIL adds to your skin’s hydrolipic film, lightly coating your skin with nutrients. It holds moisture inside and protects your skin. Its unique formula is rich in alpha lipoic acid, DMAE, essential fatty acids, vitamins C-ester and E, plus other nutrients and plant extracts. SKIN ETERNAL BATH OIL is lightly scented with pure lavender and lemon oils. And it is hypoallergenic and contains no alpha Hydroxy acids—so it can be used even on delicate, sensitive skin. Lifestyle Tips for Healthy Skin: A Strategy for WellnessSM Eat a Healthy Diet Low-nutrient foods, such as sugar and refined carbohydrates, will not provide the vitamins and minerals your skin needs. Choose unprocessed organic foods, high in antioxidants such as beta carotene (carrots, apricots, and squash), vitamin C (oranges and peppers), vitamin E (cold-pressed oils, nuts and seeds), selenium (tuna, garlic, onions and broccoli) and zinc (whole grains, most seafood, and onions). Essential fatty acids, such as those in oily fish, flaxseed and olive oil, are important for skin repair. Eat high-fiber fruits, vegetables, whole grain bread and cereals, and brown rice. Restrict excess sodium intake. Take Supplements Key nutraceuticals can help radiate beauty from within, by supporting body systems involved with healthy, radiant skin. These nutraceuticals include alpha lipoic acid, DMAE, ascorbyl palmitate (vitamin C-ester), vitamin E and grapeseed extract. Source Naturals offers you SKIN ETERNAL™ tablets with these five ingredients, to protect against free radical damage and provide cofactors for healthy skin tissue. Source Naturals SKIN ETERNAL PLUS is a Bio-Aligned Formula™, which includes these key nutraceuticals plus 30 more! It is designed to support multiple body systems: antioxidant defense, connective tissue, cell membranes, cell renewal, blood and liver cleansing, muscle and nerve function, and stress response. It is also useful to supplement with essential fatty acids, such as omega-3 and omega-6 fatty acids, flaxseed and primrose oil. Drink Water Our bodies are made up of 50-70% water, so it’s important to drink at least 1.5 liters daily. Water flushes out wastes, and acts as an internal moisturizer, keeping skin hydrated and supple. Spring water is beneficial since it contains trace minerals vital to healthy skin. Protect Your Skin from the Sun Avoid direct sun from 10 am to 4 pm, when ultraviolet radiation is strongest. Use sunscreen even during winter and on cloudy days. Wear a broad-brimmed hat and sunglasses with full UV protection. Get Plenty of Sleep Research has shown that skin regenerates itself between 1-3 am; lack of sleep during those hours can cause skin to look dull or puffy. Taking a melatonin supplement can be helpful in supporting your body’s normal sleep cycle. Exercise Regularly Exercise increases circulation, which delivers nutrients necessary for a clear, glowing complexion. It also burns off fat, helps eliminate toxins, and is a great stress reliever. Exercise three to five times a week until you are perspiring freely and breathing deeply. Avoid Excessive Alcohol and Coffee Alcohol weakens the immune system and depletes nutrients. It causes dehydration, depriving skin of moisture, and overtaxes the liver, which helps keep impurities from reaching other organs. Alcohol consumption can lead to broken or distended capillaries, especially over the nose and cheeks. Caffeine-rich beverages like coffee promote dehydration, leaving skin flaky and dry. Substitute herbal or green tea for coffee. Stop Smoking Smoking slows healing and regeneration, causes carbon monoxide to increase in blood, and induces free radical formation. Nicotine constricts blood vessels and reduces blood flow to skin. The benzopyrene in cigarette smoke inhibits absorption of vitamin C, which is important for collagen synthesis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=195) Pycnogenol Complex - The Next Generation of Antioxidant Protection 
Date:
June 04, 2005 02:14 PM
If there’s one factor that has the greatest negative impact on our health, it is the damage done to our cells by free radicals. These highly unstable molecules disrupt the biochemical processes that regulate life. Although a natural product of oxygen metabolism in the body, free radicals are also produced in vast quantities by modern technology. Our bodies’ natural defenses simply have not been able to keep up with the onslaught of these dangerous products of civilization. On the other hand, technology has offered help by identifying some of nature’s most powerful weapons against free radical attack. Source Naturals PYCNOGENOL® COMPLEX is an unprecedented combination of these extremely potent plantbased antioxidants, or Plantioxidants™. Consider them your antidote to the industrial revolution. How free radicals are formed and their effect on the body Oxygen both makes life, and takes life. The energy that animates us comes from the biochemical reactions that burn oxygen within our cells. And though carefully regulated by the body, this biological combustion, over time, inevitably leads to cellular damage. If oxidation is not carefully controlled, tissues are damaged faster than the body can repair them. This is caused by an excess of over-reactive, electron hungry molecules called oxidants or “free radicals,” which tend to disrupt normal cellular activity. Free radicals attack a cell’s membrane and can even damage its hereditary blueprint (DNA). Since free radicals are a natural result of certain metabolic reactions, the body synthesizes several types of antioxidant enzymes to neutralize them. In addition, we get essential antioxidants from the foods we eat. Vitamins C, E and beta carotene are the ones found most often in our diet. During this century, our environment has become a perpetual source of free radical contamination, primarily from radiation and the chemical pollution in our air, water and food. Today, we are literally overwhelmed with more free radicals than our bodies are accustomed to handling. Fortunately, science has found that certain plants contain special antioxidants that are far more powerful than the vitamins we typically get in our diet. With this knowledge, Source Naturals formulated PYCNOGENOL® COMPLEX, the most advanced combination of Plantioxidants available today in one product. Pycnogenol® is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima. Natural protection against free radicals Pycnogenol® Complex – A Cornucopia of Health Our knowledge of pine bark goes back nearly 500 years, to when the French explorer, Jacques Cartier, reported that a tea made from pine tree bark by Native Americans saved the lives of his crew who were dying of scurvy. Nutrition scientists have since isolated the extraordinary antioxidant compounds of pine bark. They have also discovered many other unique antioxidants throughout the plant kingdom. Plants have evolved bioflavonoids to protect themselves from free radical damage. One of the most abundant compounds in the plant kingdom, bioflavonoids are found in the pigments of bark, rinds, seeds, leaves and flowers. Natural antioxidants in Pycnogenol® Complex The active ingredients of Source Naturals PYCNOGENOL® COMPLEX are derived from a diverse range of nature’s plenty: pine bark, green tea, turmeric spice, rosemary, grape seeds, milk thistle seeds, bilberries, hawthorn berries and ginkgo leaves. Each of these Plantioxidants is an exceptional free radical scavenger, and each has a tendency to concentrate in a different organ of the body, thus providing targeted protection. And since their primary function is to capture free radicals, these Plantioxidants free up vitamin C, so it can perform its many other vital functions. Defense Plants The two headliners of Source Naturals PYCNOGENOL® COMPLEX are the pine bark extract, Pycnogenol®, and an extract from grape seeds, Proanthodyn™. Their unsurpassed antioxidant activity – up to 20 times that of Vitamin C and up to 50 times that of Vitamin E – comes from a high concentration of proanthocyanidins. Why Pycnogenol® Complex is formulated with extracts of pine bark and grape seed These highly bioavailable flavonoids are able to cross the Blood-Brain Barrier, and can stay in the bloodstream for up to 72 hours. Few other nutritional antioxidants cross this barrier, and none do it as well. Proanthocyanidins therefore offer the brain and central nervous system unparalleled antioxidant protection. In particular, proanthocyanidins may help reduce the formation of lipofuscin, a brown waste material made of free radical-damaged proteins and fats. Over time, lipofuscin deposits form in the brain, heart, and skin. The “age” or “liver” spots that develop on the backs of some elderly peoples’ hands are made of lipofuscin. Because they’re rich in unsaturated fatty acids, cell membranes are the primary site of free radical attack. Proanthocyanidins are able to protect against both water- and fat-soluble free radicals. Also, their chemical structure is incorporated within cell membranes, making proanthocyanidins very effective in preventing damage to the cell’s interior. This is vital, because if a cell’s DNA is disrupted, it could lead to the abnormal reproduction of that cell. For many years now, Europeans have used pine bark and grape seed extracts to maintain vein and capillary health. Proanthocyanidins support the circulatory system by helping to keep collagen and elastin, the essential constituents of vessel walls, from breaking down during times of imbalance. And most importantly, proanthocyanidins can help prevent the oxidation of LDL cholesterol in the bloodstream. Scientists now recognize that it’s not cholesterol itself, but the oxidation of cholesterol that can be problematic. How Plantioxidants benefit different organs in the body The Power of Diversity In addition to the broad protection offered by Pycnogenol® and Proanthodyn, Source Naturals PYCNOGENOL® COMPLEX offers an outstanding array of other Plantioxidants. Each has unique abilities to protect the body from oxidants. For several thousand years, Green Tea has been enjoyed in the Orient, not only for its taste, but also as a health tonic. Upon analysis, it contains several strong antioxidants, called Polyphenols, with exceptional free radical scavenging abilities. Polyphenols have been shown to be over 200 times more effective than vitamin E in preventing oxidative damage to brain cells. Source Naturals uses a potent extract of green tea that concentrates 2,000 pounds of fresh green tea leaves into one pound of finished product. This extract has been awarded 30 patents for its protective effects. The ancient Ginkgo Biloba tree has long been prized for its beneficial qualities. Like proanthocyanidins, ginkgo’s compounds are able to cross the Blood-Brain Barrier, and support cell membrane and capillary integrity. Its particular antioxidant constituents have been associated with superior oxygen transport to the brain. This is important because the brain uses 20% of all inhaled oxygen. Source Naturals PYCNOGENOL® COMPLEX uses a superior 50 to 1 extract, providing 24% Ginkgoflavoneglycosides and 6% Terpenoids. Bilberries were first studied for their capacity to heighten visual acuity in normal subjects under poor light conditions. In fact, to increase their night vision, RAF pilots ate bilberry jam during WW II. Its antioxidant compounds, Anthocyanosides, have an affinity for delicate eye tissues, where it quenches free radicals and supports capillary strength. Source Naturals utilizes a standardized bilberry extract with 25% anthocyanosides, 80 times more potent than regular bilberry. The wide range of natural antioxidants in Source Naturals PYCNOGENOL® COMPLEX Milk Thistle Seed Extract has been researched and used for over 20 years in Europe. Its antioxidant compound, called Silymarin, has a special preference for the liver. It’s one of the few nutrients that can support the liver’s natural regenerative processes. By enhancing DNA activity, liver cells can regenerate up to five times faster. Turmeric Extract contains 95% Curcumin, the active ingredient of this traditional East Indian spice. Curcumin promotes the body’s own production of antioxidant enzymes, including glutathione peroxidase, an important protector of the liver. Curcumin also increases the production and secretion of bile, which is used to remove cholesterol from the body. Quercetin has been well-researched for its free radical scavenging activity. Because of its ability to stabilize cell membranes, quercetin helps prevent damage and discomfort from reactionary (histamine- and leukotriene-related) processes in the body. Source Naturals quercetin has been isolated from plant sources. Rosemary and Hawthorn Berries both contain bioflavonoid antioxidants that have the unique ability to neutralize the Hydroxyl radical, a particularly dangerous type of free radical. Hydroxyls are produced by exposure to excessive radiation and pollution from burned fossil fuels. The body has no innate defense system against it. Vitamin C is one of the most active and abundant antioxidants in the body, so it must be frequently replenished. Since it works in conjunction with bioflavonoids, each tablet of Source Naturals PYCNOGENOL® COMPLEX contains 500 mg of vitamin C, bound to Magnesium for increased bioavailability. A World of Help As we better understand how free radicals affect our health and well being, it’s important that we take advantage of the wonderful protective qualities found in certain plants. These Plantioxidants provide the appropriate means to counteract the destructive effects of excessive free radicals, which have become part and parcel of modern life. Source Naturals PYCNOGENOL® COMPLEX brings the diverse and concentrated power of the plant world into your world of wellness.
References
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Introduction
What is Citrimax
5-Hydroxytryptophan (5-HTP) is a substance derived from Griffonia simplicifolia’s seed pods. In the human body, 5-Hydroxytryptophan is an immediate nutrient precursor to neurotransmitter serotonin. This implies that 5-HTP directly converts into serotonin in human brain. Serotonin plays very many essential functions such as; a role in appetite, learning, sleep, memory, temperature regulation, cardiovascular function, endocrine regulation, sexual behavior, mood and muscle contraction.
The Acai is basically a type of berry that grows on the Acai palm trees, well known to be a natural flora of the Amazon Rainforest. For a long time, it has also been on cultivation in some parts of the Southern and Central America as a foodstuff. These berries are known to have various varieties but there are two distinct types of Acai berries: the ones that remain green upon ripening and the ones that turn into dark purple color upon ripening. Scientific research has it that the ripe-green type has more oil constituents while the ripe-purple variety has less oil but a wider range of antioxidants. 
It has become a national obsession to find a quick fix for obesity. In the long run, prescription drugs have not proven to be safe or effective. Additionally, just about all diets fail. There have been some natural supplements that have been found to be both beneficial and safe. One of the most promising of these supplements is griffonia, which is extremely high in 5-Hydroxytryptophan, which is also referred to as 5-HTP. 
Garcinia is part of the plant genus in the family Clusiaceae. This plant is native to Asia, Austrlia, tropical and southern Africa, and Polynesia. The number of species of the garcinia plant is highly disputed, but various sources recognize between fifty and three hundred species that are specifically valid. The plants in this genus are commonly called saptrees, mangosteens, or monkey fruit. 
Studies have determined the significant weight-loss benefits on both animals and humans when using garcinia. One study, which involved fifty obese patients, gave 500 mg of garcinia rind to these patients daily, along with 100 mg of chromium. This was also combined with a low-fat diet. The individuals who were taking the garcinia-chromium lost an average of eleven pounds, while the control group reported only a four-pound weight loss. 
Pau d'arco is known in South America for its healing powers by the Callawaya tribe. These people called the herb taheebo and have been using it for over one thousand years. This herb was used anciently by the Inca civilization's medicine men. Pau d'arco was included in traditions that were passed down through the generations. Pau d'arco has been used to treat cancer and other illnesses since the 1970s in the Santo Andre Hospital in Rio de Janeiro, Brazil. This herb has become a well-known herb for healing and protecting the body from disease. 
It is often referred to as the “everything” herb due to its uses for many disorders. Pau d'arco has been used by many, along with other medications. There seem to be no problems that are associated with the combination. It is also used to help counteract the side effects of some medications and is believed to reduce the liver damage that is caused by some drugs. Many herbalists have used this herb to treat a variety of conditions. It is effective as an immune system enhancer. It can also aid in treating conditions such as cancer, leukemia, tumors, and blood disorders. Pau d'arco is also used to treat the pain of arthritis and also for diabetes, candidiasis, herpes, liver ailments, hypoglycemia, and assimilation of nutrients. 
