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Search Term: " Inhibiors "
Use warm water and turmeric to cleanse your body, support digestion   
Date:
May 10, 2019 02:25 PM
It is estimated that a lot of Americans are affected by digestive problems. Gastroesophageal reflux disease (GERD) alone affects about 20 percent of Americans according to a 2010 estimate and that number should have increased by now. Pharmaceutical products being used to treat these symptoms can do more harm than good. Some of the drugs used for proton pump inhibitors of which 113 million are prescribed every year have been identified as the cause of bone fractures in older women and clostridium infections that result in diarrhea and life threatening conditions in older people. Some natural products though can do the work of cleansing your digestive system without the side effects and also help detox the body. One of them is turmeric. Just add some turmeric in warm water and one is ready to have these benefits. Warm water on its own is very important to the body but when mixed with turmeric it will help create bile that breaks down and absorbs fat in the body. Bile eliminates wastes in the body thereby detoxing your body the natural way. Key Takeaways:
"Turmeric mixed in a warm glass of water will not only help cleanse your body, but they will also lend support to your digestive system." Read more: https://www.naturalnews.com/2019-04-03-warm-water-turmeric-to-cleanse-your-body-support-digestion.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6307) Exotic spice saffron found to be safer, more effective thanantidepressants 
Date:
April 23, 2019 02:51 PM
Saffron has been used for centuries in treating various ailments both mentally and physically. Recent studies are showing support in the fact that this exotic spice can do wonders for those who are suffering from depressive symptoms. In fact, a recent control group proved that when people take adequate amounts of saffron on a routine basis, it has the ability to alleviate their symptoms just as much as mainstream antidepressants such as Prozac and other serotonin inhibitors. Key Takeaways:
"Along with the growing rates of depression, the use of antidepressant medication has continued to skyrocket. Some 2013 estimates from the CDC reveal that usage of these drugs increased by upwards of 400 percent in just 25 years." Read more: https://www.naturalnews.com/2019-02-27-exotic-spice-saffron-safer-more-effective-antidepressants.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6163) Natural remedy for OCD may lie in ashwagandha
Date:
February 11, 2019 11:11 AM
Physicians typically prescribe patients mainstream pharmaceutical drugs called selective serotonin reuptake inhibitors (SSRIs), and cognitive behavioral therapy (CBT) as a way to treat obsessive-compulsive disorder (OCD), but new research is showing that another effective route may be available. Ashwagandha roots can be put into a powdered extract that can be combined with lactose in order to treat symptoms of OCD. A six week trial proved that after 30mg of ashwagandha each day, patients who suffered from anxiety noticed that their symptoms improved at the end of the trial. Key Takeaways:
"Patients may finally get their obsessive-compulsive disorder (OCD) under proper control thanks to an ancient Indian herbal remedy." Read more: https://www.naturalnews.com/2019-01-09-natural-remedy-for-ocd-may-lie-in-ashwagandha.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6016) Anti-cancer breakthrough: 52 herbs were tested, and only these three were found to effectively fight cancer
Date:
August 19, 2017 12:14 PM
Natural herbs have been used medicinally for centuries. Ancient civilizations have used them to cure many minor and major ailments. These herbs are now being studied to treat strains of cancer. Scientists from King Abdullah University of Science and Technology have reviewed the high contrast image screening of 52 herbs to test their properties that may affect cancer. In all of these 52 herbs three have showed promising results. They all originate in the middle east and include Citrullus colocynthis, Anastatica hierochuntica, and Juniperus phoenicea. More testing is necessary. With the discovery of these herbs' possible treatment powers, more people are hopeful to discover new herbs in such places as the Amazon Rainforest. Although recent deforestation is an issue. Key Takeaways:
"The three plants that showed a lot of promise were Anastatica hierochuntica, Citrullus colocynthis, and Juniperus phoenicea. All of these had potent anti-cancer substances known as topoisomerase inhibitors that could potentially be used to develop anti-cancer inhibitors." Read more: http://www.naturalnews.com/2017-08-15-anti-cancer-breakthrough-52-herbs-were-tested-and-only-these-three-were-found-to-effectively-fight-cancer.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5149) How safe are heartburn medications and who should use them?
Date:
August 11, 2017 04:14 PM
Heartburn medications that are currently prescribed might not be the most effective in treating heartburn. Many people suffer from heartburn and many of those people are prescribed what is known as "protein pump inhibitors." These medications prevent stomach cells from producing stomach acid, which causes heartburn. However, these medications often need to be taken for long periods of time and may lead to early death. While studies show proton pump inhibitors are effective at reducing heartburn, one study found a small increased risk of early death for those taking these medications and other studies have linked negative side effects, like vitamin B12 deficiency, to proton pump inhibitors. Nevertheless, the benefits outweigh the risks. Yet, it seems as though too many proton pump inhibitors are being prescribed than are necessary. Therefore, only those suffering from extreme heartburn should be prescribed proton pump inhibitors, as they can be very beneficial to treating their condition. Key Takeaways:
"A study found these drugs were very effective for treating reflux disease, with eight weeks of therapy with standard (once daily) dosing healing acid damage in more than 80% of patients." Read more: http://theconversation.com/how-safe-are-heartburn-medications-and-who-should-use-them-80809
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5109) Depression: does it originate in the immune system?
Date:
December 04, 2016 12:59 PM
While it is true that 1 out of 10 people are affected by depression, the cause of it is controversial. For years we have believed that low serotonin levels were the cause of mood disorders. New research now suggests that mood disorders could be caused by the body's immune system. Those antidepressants that some have been taking, may not have worked if serotonin levels weren't to blame. Key Takeaways:
"For decades, we've been told that serotonin is the key culprit for mood disorders, but now a growing number of doctors are subscribing to a radical new theory of depression - that the problem, at least for some people, is in fact the result of inflammation in the body, caused by the body's immune system reacting to an infection or stress." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3567) Reflux and ulcer medications linked to kidney stones and chronic kidney disease
Date:
December 04, 2016 07:59 AM
A University in Rome has found information that links medications taken for acid reflux and heartburn to a higher incidence of kidney stones. By reviewing patient files, they found that patients who took proton pump inhibitors were at a 12% higher risk of developing kidney stones throughout their lives, and those who took histamine receptor-2 were at a 13% higher risk. They have stated that more research needs to be done, but any link between the medicine and kidney stones is cause for alarm. Key Takeaways:
"Proton pump inhibitors (PPIs) and histamine receptor-2 (H2) blockers are commonly used to reduce gastric acid production." Reference: https://www.sciencedaily.com/releases/2016/11/161118130351.htm
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3564) Protein drives inflammation in rheumatoid arthritis patients
Date:
November 28, 2016 08:59 AM
A recent study found that patients suffering from rheumatoid arthritis with higher levels of the protein type 1 interferon beta do not respond as well to treatment with tumor necrosis factor inhibitors. This research will prove to be invaluable in the future in order to personalize treatment plans for people with rheumatoid arthritis. Key Takeaways:
"A recent research has found that a certain protein in the body causes inflammation in rheumatoid arthritis patients which in turn will help avoid trial and error when prescribing medications." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3524) Your Mood and mental health
Date:
September 20, 2016 11:52 AM
Bipolar disorder is a terrible mental disease that affects millions of people worldwide. It is characterized by periods of severe depression, followed by periods of extreme euphoria. It can be rapid cycling, which means the person with the disease goes through many moods a day.
Once you figure out what the underlying cause such as brain chemistry, then you can take a natural approach to help boost serotonin or dopamine. Always remember to be careful if on MAO inhibitors or SSRI inhibitors before taking natural remedies like 5-htp or dopabean to mess with serotonin and dopamine levels in the brain.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3300) Does Broccoli Really Fight Cancer?
Date:
May 27, 2014 05:23 PM
Cruciferous vegetables such as broccoli is known to have numerous health benefits within the body. In addition, many studies have proved that broccoli has another element known as sulforaphane that has cancer-fighting properties. Benefits of broccoli A recent study by the Oregon State University, suggested that sulforaphane is a powerful antioxidant in broccoli and many other cruciferous vegetables do have the power and the ability to kill cancer cells, thus leaving the prostate cells unaffected. Sulforaphane is also another potent antioxidant that has the ability to inhibit HDAC enzymes known as histone deacetylase and play a vital role in suppressing tumor-like genes thus making a perfect solution to cancer treatment. HDAC in Cruciferous vegetables such as broccoli is known to have numerous health benefits within the body. In addition, many studies have proved that broccoli has another element known as sulforaphane that has cancer-fighting properties. A recent study by the Oregon State University, suggested that sulforaphane is a powerful antioxidant in broccoli and many other cruciferous vegetables do have the power and the ability to kill cancer cells, thus leaving the prostate cells unaffected. Sulforaphane is also another potent antioxidant that has the ability to inhibit HDAC enzymes known as histone deacetylase and play a vital role in suppressing tumor-like genes thus making a perfect solution to cancer treatment. HDAC inhibition is another very promising cancer treatment and many researchers have found that it is associated with broccoli. Cancer is often characterized by the inappropriate cell growth, however, HDAC inhibitors has the ability of restoring cells to normalcy in terms of function and thus the most effective cure of cancer. Other studies have also demonstrated the cancer-fighting ability of the cruciferous vegetables. In the year 2009, Victoria Kirsh., of Toronto Cancer Care Ontario and her team discovered that eating vegetables and fruits in general was associated with the decreased prostate cancer risk, making it one of the best ways of enhancing health. This remarkable compound in broccoli is among the strongest anti-cancer elements in the body. It is important to recall that you cook your broccoli in the best way possible since this will preserve the elements that helps in fighting cancer. In addition, Broccoli has myrosinase that helps in the formation of sulforaphane. You need to remember that Myrosinase is an element that can be destroyed through overcooking the broccoli. You should only steam it for 2 to 4 minutes. In conclusion, the above information should convince on the incredible ability to cure the cancer cells that are found within the body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3127) Can Glutamine Improve Nitrogen Balance in the Body?
Date:
May 07, 2014 09:08 AM
Can Glutamine Improve Nitrogen Balance in the Body? Essentials of glutamine have been found to be many. Nowadays there are commercially produced glutamine which are taken as strong anti-catabolic supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3113) Calcium and magnesium - vital to health
Date:
December 20, 2012 02:06 PM
Calcium and magnesium are two essential minerals for the body, bringing serious damage if there is a deficiency. Calcium is essential for maintaining bone strength in the body, but also for the functioning of nerve and muscle cells. Bones perform several roles in the body, but most of us are interested in the preservation of acid-base balance (pH). When the pH of the blood is too acidic , bone alkaline elements released (alkali salts) to neutralize acids. This leads to loss of bone mass (and calcium), while rapidly releasing toxins and heavy metals stored in bone if there are metals and toxins present. Most of us know that calcium is found in dairy products. True, but the information is not complete. You should know that of all dairy products, yogurt offers the most calcium, about 200 mg in a cup. But if you want the most bioavailable calcium, ie one that is most easily absorbed and can be used fully by the body, then you need to take calcium citrate. If the food based calcium intake is not optimal and extremely diverse, then you need calcium-based vitamin supplement products. Calcium supplements may be consumed with meals for maximum digestion and absorption. But even if you take dietary supplements, diet should not remain poor, continue to get adequate amounts of calcium from food sources. Magnesium has an important role in the efficient functioning of the nervous system, muscular system and enzyme processes in the body. It is necessary for calcium absorption. The ratio of the two minerals is especially important. An adult daily needs for bone health by around 1,500 mg of calcium and 1000 mg of magnesium. Bones are living tissues that rebuild constantly. A healthy diet, exercise, enough sleep (at least 8 hours) and keeping well hydrated with water helps strengthen bones. Calcium and magnesium, combined doubles benefits to our body, especially if they are of citrate in origin. Cal-Mag Citrate Why? Studies have shown that calcium and magnesium citrate is the easiest form to digest with minimal stomach acids. This make it work great for older individuals who have low stomach acids or who are on proton pump inhibitors.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2758) Supremacy of Pea Protein Over The Other Protein Sources
Date:
March 01, 2012 08:53 PM
Supremacy of Pea Protein Over The Other Protein SourcesProtein is essential for your overall health and it is considered as the valuable source of energy. You can meet your daily protein requirements by eating various animal products such as meat and milk. It can also be obtained by consuming some dietary supplements. Pea protein is a new alternative protein powder, which is manufactured by using yellow peas. This is allergen free, easily absorbable and coming with great taste. Pea protein is ideal for people who are intolerant to lactose. You can also use it if you cannot digest milk and meat properly. Due to the high digestion rate, this protein is used to complement non dairy foods, pastas, beverages, and a number of meal replacement shakes. You can also regulate your appetite effectively and can reduce weight significantly by using pea protein. If you consume pea protein before and after your weight training session, you can achieve your body building goal very easily. This protein contains chain amino acids, which is helpful for restoring your muscle. It is also beneficial for treating some chronic diseases like kidney problems. Benefits of Pea Protein over Other Protein Sources Pea Protein Vs Whey Protein Compared to other protein supplements, whey protein is very popular because of high biological values and chain amino acids. Your body can also absorb it very quickly. However, it is also very allergic due to the presence of lactose or casein. Though whey protein is coming either without or very less content of these two products, bovine serum albumin, alpha-lactalbumin, and beta-lactoglobulin in whey protein are highly allergenic. The cholesterol content in whey protein is also very high. Pea Protein Vs Soy Protein Soy protein cannot be considered as an effective alternative and it also contains high allergens. If you eat more soy protein, chances of developing allergies will also be very high. If the phytates content is not removed, soy protein prevents the absorption of major minerals like calcium. If soy protein has not been fermented, it can contain potent enzyme inhibitors, which leads to the blockage of the activities of trypsin and the other enzymes needed for the digestion of protein. This leads to the formation of gas and the promotion of pathological conditions in pancreas. Once, soy oil industry considered soy protein as a waste product and it was used as cattle feed. Pea Protein Vs Milk Protein Milk is the primary source of protein but the milk protein supplements create problems such as diarrhea, stomach cramps, gas, etc. You may also develop lactose intolerance due to the consumption of milk protein. A large number of food allergies, such as fatigue, constipation, diarrhea, etc, are caused by milk products. It can also cause asthma and sinus infections. Pea is a member of plant family and there is no need of using complicated methods for extracting protein. These are also grown in environmentally friendly way. The defenses of your body can be broken down due to exercise, aging and stress. When you become old, you will be more vulnerable to diseases, infections, oxidative damages, and tissue degeneration. These problems can be solved by using pea protein powder.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2598) How Does Holy Basil Extract Help With Pain
Date:
June 06, 2011 02:43 PM
Holy Basil And Your Health.
Holy Basil, technically known as Ocimum tenuiflorum, is a perennial plant which is a member of the family Lamiaceae. This kind of plant is commonly cultivated in the tropics region but can also be seen as an escape weeds. Holy Basil plant is an upright shrub with many hairy branches that can grow up to 30 to 60 centimeters in height. It has an aromatic leaves in green color that are slightly toothed. It also bears flowers which are purple in color and also has a strong scent. Holy Basil has many medicinal uses. In fact, in South Asian regions, Holy Basil is commonly utilized as an herbal tea. Holy Basil claimed to be an effective pain treatment. Clinical studies show that this plant contains high amounts of Eugenol which mimics the actions of COX – 2 Inhibitor drugs. COX – 2 Inhibitors is a pain killer which is classified as Non – Steroidal Anti – Inflammatory Drug or NSAID. This type of drug is directly targets the enzyme Cyclooxygenase – 2 which is responsible for inflammatory response. Inflammation is associated with swelling which further cause pain. If an area is swollen, the nerve endings are compressed therefore pain is felt. Aside from its potent pain alleviating property, Holy Basil is also useful in reducing blood sugar levels. This is the reason why it is utilized as an effective treatment for diabetes mellitus. Holy Basil also has an antioxidant effect. As we know for a fact, antioxidants are useful in eliminating harmful toxins in the body known as free radicals. Free radicals can damage cells and even tamper DNA formation during cellular division. Other benefit of Holy Basil includes its anti – stress property. Holy Basil leaves are considered to be an adaptogen or anti – stress agent which protects an individual against various stressors. Experts recommend that an individual can consume a dozen of Holy Basil leaves two times daily to prevent stress. Holy Basil leaves are thought to purify blood thus improving blood circulation and tissue oxygenation. Aside from Eugenol, Holy Basil also contains the compound Carvacrol which has a strong antibacterial property. Carvacrol has the capacity to inhibit the growth of certain bacteria such as E. coli and Bacillus cereus. Carvacrol is also an effective digestive aid. Research reveals that Carvacrol is can alleviate gastric upset and improve digestion of food and absorption of nutrients. Holy Basil extracts are reported to be safe and effective in helping alleviate pain and treating other health conditions. Experts suggest that Holy Basil is not for long – term use. It must be used only for a maximum of four weeks. Pregnant women and breastfeeding mothers must not use this supplement to be completely safe. Holy Basil is discovered to slow blood clotting therefore it must not be used within two weeks before and after any type of surgery. Finally, though Holy Basil extracts are relatively safe, it would still be best to consult a qualified healthcare provider and discuss with him or her your health status and history. Get some today and reap the benefits of this wonderful herb for yourself!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2323) What is Red Marine Algae And What Are Its Health Benefits?
Date:
June 01, 2011 04:21 PM
Red Marine Algae And Your Health.Red marine algae refer to a large group of seaweeds that contain phycobiliproteins, which give them their red coloration. They are simple organisms in that they do not have complex tissues in contrast with terrestrial plants. Many species of red marine algae plays an important role in the formation of coral reefs as they secrete calcium carbonate as well as provide nutrition for other marine species. Like plants, they are capable of making their own food by way of photosynthesis. And like most other seaweeds, they are excellent sources of vitamins, minerals, and other healthy organic compounds. Scientific Classification Rhodophyta is the taxonomic classification of all red marine algae. It is oftentimes considered a part of the plant kingdom, but more recent definitions of plant suggest red algae belong to a kingdom of their own. Rhodophyta is one of the largest groups of algae, second only to green algae. It consists of up to 6000 aquatic species that are widely distributed in the tropical, temperate, and even frigid zones. These species usually take up residence along the coastal regions and significantly contribute to the distribution, abundance, and ecology of organisms found in the extended perimeter of each continent. Historical Uses Seaweeds have become a part of the staple diet of many communities throughout history, and red marine algae are one of the best sources of human nutrition among all seaweeds. For thousands of years, different species of red algae have enjoyed significant presence in cuisines from all over the world. It is often consumed uncooked or added to salads. It is also an important ingredient in soups and stews. Ocean farmers have learned different techniques of domesticating crops of algae, and cultivation has been the solution to the growing demand of red marine algae in the past few decades. Industrial Applications Red marine algae have steadily grown in economic value since the 20th century. In addition to their historical culinary uses, their application now extends to medical science. Several organic compounds have been isolated from different species of red marine algae are now in wide use in the food and drug industries. For example, gelatinous substances are derived from agarophytes, any species of seaweeds that belong to rhodophyta. These substances are used in the production of beer, food preserves, ice cream as well as papers, fabrics, lubricants, and other personal care products. Medicinal Value Red marine algae have a special place in antiviral research. Many species are now identified to contain organic compounds that are of medicinal value against several viruses. Decades-long studies have come to a conclusion that sulfated polysaccharides derived from red marine algae have an inhibitory effect on replication of herpes simplex virus (HSV). There is good evidence that one class of sulfated polysaccharides called carrageenan offer some protection against transmission of herpes. Furthermore, recent studies have revealed that sulfated polysaccharides are potent inhibitors of HIV-1 in cell culture. Red marine algae is an excellent source of nutrients found in the sea. Get some red marine algae and reap the benefits of this nutrient rich food today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2316) Boost Brain Chemistry, Lower Bad Cholesterol, And More
Date:
May 12, 2011 01:27 PM
What is Inositol Good for?Inositol is an organic compound present in many plant-based foods. Popular nutritional sources of inositol include brown rice, wheat bran, whole grains, beans, nuts, and other foods rich in fiber. It is a polyphosphorylated carbohydrate that was once classified as an essential nutrient together with B-complex group of vitamins. It is an important component of signal transduction of cells, amplifying the strength of signals from the receptors on the cell surface to target molecules within the cytoplasm. Cancer research on inositol is one of the most publicized. Fruits and vegetables that are known for their high fiber content also contain large amounts of inositol, which is believed to prevent the inactivation of DNA repair gene and protect the cells from mutation that lead to carcinogenesis. In laboratory studies it has shown great medicinal potential as a therapeutic remedy for various cancers. In addition, it has been extensively utilized in the treatment of psychiatric disorders. Rebalances Brain Chemicals Supplementation of high dose inositol has been observed to be beneficial to sufferers of mental illnesses. There have been numerous clinical trials focused on its effects on the chemical compounds found in the central nervous system, and early studies recorded that its mechanisms of action are similar to a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs. A growing body of scientific literature is devoted to its purported role in the amelioration of anxiety disorder, panic disorder, obsessive-compulsive disorder, clinical depression, and bipolar disorder. It has been favored over some SSRIs because of its desirable results and absence of side effects. It has particularly benefited individuals diagnosed with obsessive compulsive disorder, with testimonies being largely positive. Also, it has been reported to also reduce frequency of panic attacks. Lowers Bad Cholesterol High-fiber diet has always been recommended to manage high cholesterol levels. It emphasizes the intake of whole grains, fruits, and vegetables. The same group of foods is rich in the carbohydrate inositol. In the latter half of the 20th century, it was discovered that inositol in fact contributes to the breakdown of fatty molecules, such as triglycerides, in the gastrointestinal tract and interferes with their absorption. More importantly, regular consumptions of inositol appear to reduce overall lipid levels in the blood. It is postulated that it blocks the metabolic pathway that integrates triglycerides in very-low-density lipoproteins, the immediate precursors of low-density lipoproteins, also known as bad cholesterol. By so doing, it not only lowers cholesterol and free fatty acids found in systemic circulation but also prevents cardiovascular diseases, such as atherosclerosis. Other Benefits Many nutraceutical products that contain inositol are commercially touted to aid weight loss. Inositol has also been associated with the alleviation of digestive problems, most notably constipation. It is believed to soften the stool by attracting water as it works its way into the alimentary canal, and regular intake promotes regularity. Furthermore, it has been linked to hair growth as low levels of inositol have often been tied to hair loss. Taking a inositol supplement can help you obtain all the inositol you need for your daily needs!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2294) Improve Your Memory Naturall, How Does Huperzine A Help Improve Memory?
Date:
March 26, 2011 10:47 AM
Huperzine A and The BrainHuperzine A is an organic compound naturally occurring in a plant species believed to be one of the oldest vascular plants still in existence. It is derived entirely from the firmoss Huperzia serrata, which is reputed for its memory-enhancing effects in China for the most part of its history. It has gained the attention of researchers and health professionals in the West owing to its purported role as a cholinesterase inhibitor, which delays cognitive decline and brain shrinkage tied to Alzheimer’s disease. It has become popular to people seeking other forms of cholinesterase inhibitors apart from those commonly available in the market, and anecdotal evidence points to its noticeable effects on symptoms of Alzheimer’s disease. Increases Quantities of Neurotransmitters Cholinergic neurotransmission makes use of a system of nerve cells that participate in anti-excitatory activities in the central nervous system. These neurons rely on an endogenous compound called acetylcholine, which acts as the primary neurotransmitter in the brain, the brain stem, and the spinal cord. Acetylcholine as a neurotransmitter is synthesized from esterified acetic acid and choline, but its lifespan is cut short by the enzyme cholinesterase. This enzyme induces the hydrolysis of this neurotransmitter back into choline and acetic acid. Huperzine A works on the principle of inhibiting the enzyme cholinesterase, resulting in a longer acetylcholine lifespan especially those in the brain. By doing so, it also raises the levels of other neurotransmitters that are in the employ of nerve cells. Affects Chemical Compounds in the Brain Nerve cells constantly respond to many chemical brains that may induce more neuronal activities that affect cognitive function. The busier nerve cells become, the sooner the brain is able to sustain concentration. An increase in neurotransmitters has been tied to greater neuronal activities. Also, there are exogenous chemical compounds that when ingested pass the blood-brain barrier and act as stimulants to nerve cells, such as caffeine. It has been postulated that Huperzine A provides a nootropic effects by influencing endogenous brain chemicals and consequently stimulating neuronal activities in a similar way caffeine does. However, unlike caffeine, it is not considered a psychoactive drug. More importantly, a more recent study points to its effects on nerve growth factor, or NGF, a protein responsible for the growth and upkeep of nerve cells. This means Huperzine A not only influences brain chemicals, but also makes sure that nerve cells survive. Creates Positive Effects on Neuroplasticity In contrary to former claims that the brain does not change after early developments during infancy, recent studies point to changes in both chemical makeup and cellular structure as we age. These changes are a response to both physiological stimulus and learning experience. New nerve cells are created as we spend more time sharpening our mental skills, much like how the muscles respond to continuous exercise and body toning. This process of change in the brain is called neuroplasticity, which Huperzine A supports by acting as a vitamin-like nutrient to nerve cells and neurotransmitters. If you want to improve brain function and memory, give Huperzine A a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2259) How can I Tell if I am Magnesium Deficient?
Date:
February 09, 2011 01:25 PM
Magnesium The Essential Mineral Magnesium is a dietary mineral that has established nutritional values in most countries. The presence of magnesium inside the human body involves many different chemical reactions, assisting more than 300 enzymes in their functional roles. That’s why we need to meet the daily recommended allowances for this dietary element, which has been calculated by the scientific community to supply the body with amounts adequate to support body functions. An Essential Mineral Not all enzymes are capable of producing the effects that they are programmed for on their own, and enzymes identified to rely on the presence of magnesium can be traced in almost all metabolic pathways. Molecules that comprise the structural units of RNA and DNA are extensively used as a source of energy of all cells, such as adenosine triphosphate or ATP. When enzymes utilize ATP for energy, they require another molecule that secures their binding to ATP, which is magnesium. In addition, ATP being the main source of energy that powers the functional roles of cells more often than not necessitates that it be bound to a magnesium ion to be fully activated. Absorption Problems
Magnesium is ubiquitous in nature, and green leafy vegetables are ideal sources of this dietary element as well as nuts, wheat, seafood, and meat. In spite of that, it has been reported that in the US alone more than 60 per cent of the population does not meet the recommended daily intake for magnesium. The availability of magnesium in our diet does not ensure absorption of this essential mineral, and a significant fraction is in fact excreted along with other waste products in the urine or feces. Interestingly, diet high in protein or fat actually interferes with the absorption of magnesium.
Magnesium DeficiencyA general feeling of malaise must not be taken lightly, for it is key indicator of magnesium deficiency. Magnesium is indispensable at the cellular level, and insufficient amounts of this element will certainly affect the way you feel, bringing about the perception of fatigue. If you feel weak all the time for no known reason, then it is recommendable to visit your doctor and find out if you have an alarming case of magnesium deficiency. Keep in mind that high concentrations of protein and fat in the foods that you eat contribute to malabsorption of magnesium, and subsequently malnutrition. Certain medical conditions are known to deplete your reserves of elemental magnesium present in your body, notably diabetes mellitus. Drugs and medications also washes away the magnesium found in your diet and your body especially osmotic diuretics, cisplatin, ciclosporin, amphetamines, and possibly proton pump inhibitors. Continued exposure to stress and excessive intake of alcohol both result in the unhealthy drop of magnesium levels in the blood. While there are environmental settings that we may not be able to alter, we can certainly control what we ingest. Supplementation is the only surefire remedy for magnesium deficiency, but the best way to combat whatever symptoms you are experiencing is to seek medical advice.
It is Essential You Get Your Magnesium Daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2234) How does Malic Acid help with Fibromyalgia?
Date:
February 09, 2011 01:18 PM
Malic Acid And Fibromyalgia
If you feel sensitized to pain by otherwise harmless stimuli, then you may be experiencing symptoms of fibromyalgia, which has been recorded to affect up to 4 per cent of the population worldwide. It is characterized by a feeling of weakness in the muscles of the limbs, conscious awareness of abnormal heartbeat, problems concerning bowel movement, and disturbances to sleep patterns. All of these are complaints reported to have been addressed by supplementation of malic acid. The medical community remains inconclusive as to what causes fibromyalgia, some claiming it’s not a disease at all. While symptoms may not be necessarily medical signs, there are innumerable cases that describe complaints we collectively refer to as fibromyalgia. Throughout the past few decades, medical professionals around the world have considered these symptoms as one musculoskeletal disease whereas most neurologists have contended that fibromyalgia is attributable to the abnormalities within the nervous system. Today the American College of Rheumatology has charted nine paired tender points in an effort to describe the symptoms for this condition better. Known Causes in Scrutiny The most common symptoms of fibromyalgia more often than not appear simultaneously with stress-induced medical conditions such as chronic fatigue, anxiety disorders, and depression, but they are known to develop independently. A tissue in the brain responsible for long-term memory and spatial navigation called hippocampus have shown abnormalities among patients of fibromyalgia, thereby affecting sleep patterns, perception of pain, and related cognitive functions. In the latter half of the 20th century it is postulated that serotonin leads to fibromyalgia. Serotonin being a neurotransmitter that governs mood, attention, and pain were found to be significantly decreased in the blood plasma and cerebrospinal fluid among patients who reported to experience this condition. That being said, the introduction of serotonin inhibitors used in treatment of depression has also shown alleviations of pain-related symptoms across the tender point index.
Malic Acid and PrognosisMalic acid was discovered as a constituent of apple juice as early as the 18th century. Reduced levels of malic acid contribute to the maturity of fruits. In human beings it plays a fundamental role as an intermediate in a metabolic pathway that influences the chemical conversion of bioactive compounds like carbohydrates, fats, and proteins into carbon dioxide and water, which in turn convert the molecules contained in the cytoplasmic fluid of cells into energy generated in the mitochondria. The availability of malic acid inside the human body modulates functional activities at the cellular level by speeding up the metabolism of bioactive compounds and consequently the production of energy in use by the cells. That being said, malic acid provides vitality to muscle cells, raising their endurance against stress. In addition, there have been reports that intake of malic acid help elevate levels of serotonin, leading to improved response to pain and better management of fibromyalgia. For now, the tender point index is the primary diagnostic tool for evaluating fibromyalgia, and the use of malic acid has been recorded to reduce pain in these points.
Have you had your Malic Acid today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2233) Herbs For Depression
Date:
December 13, 2010 12:34 PM
Fight Depression with Natural Herbs Before discussing treating depression with natural herbs we should first consider depression itself: what is it and what causes people to become depressed? Psychiatrists and psychologists will suggest a number of definitions although most experts agree that there are two forms of depression. Causes of Depression Exogenous depression comes about as a result of external factors such as bereavement, heavy debt, job loss, etc, while endogenous depression comes from within and is believed to be due to biochemical problems, including food allergies, hormonal changes, thyroid problems, nutritional deficiencies, particularly Vitamin B deficiency, and addictions. There are many other reasons for people becoming depressed, some of which can be established by the particular symptoms of the individual. In many cases of depression the external factors are often easier to treat than those due to internal factors. Many exogenous causes of depression such as bereavement are alleviated through time, while causes such as job loss and debt can be resolved once the cause has been rectified: thus, if the patient is no longer in debt or is re-employed, the depression tends to disappear with the cause. Symptoms of Depression Depression is not diagnosed from a single symptom, but from a number of symptoms that can point to a person being clinically depressed and requiring treatment. Among the symptoms of depression are:
Prolonged periods of sadness or despair Forms of Depression Many normal people can suffer one or two of the above systems, and would not be diagnosed as depressed because of it. We can all get mood swings, feel a bit worthless now and again or be unable to concentrate or focus at times, but that does not mean we are clinically depressed. Depression would not be diagnosed in a patient with just one of these symptoms but five or more likely would be. In fact, the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders deem the patient suffering clinical depression if displaying 5 or more of the bottom 8 symptoms above for a month or more. This is believed to be the case with around 17 million Americans so it is a significant problem. Manic depression is otherwise known as bipolar disorder, where patients have large mood swings from high and extreme hyperactivity and excitability to very low deeply depressive moods and is a clinical condition generally treated using drugs. Treatment of Depression With Natural Herbs The usual treatments are drugs that often have undesirable side effects; so many people are trying natural remedies instead. There are a number of herbs that can be used to treat depression, one of the most familiar being St. John's Wort. However, there are others, and here is a synopsis of each. St. John's Wort
However, it can also be used in cases of severe depression, and a report in the Cochrane Database Review[8(4)] by K. Linde, M.M. Berner and L. Kriston in 2008 stated that of 29 separate tests carried out on a total of over 5,000 patients, the conclusion was that St. John's wort extracts were at least as good in treating severe depression with 5 times lower side-effects as tricyclic antidepressants and twice lower than the new selective serotonin reuptake inhibitors (SSRI).
It should be stated, however, that one trial on 340 subjects indicated no improvement over a placebo. However, the anti-depressive drug sertraline (Zoloft) was also shown to be no better than the placebo in this test, so some doubts must lie regarding its accuracy. Of all the herbal treatments, St. John's wort has had most testing carried out and it seems to be effective in treating mild to severe depression although not all experts are yet agreed. Kava Kava Root
However, it is doubtful if its effects are permanent and so it may be less of a depression cure as a short-medium term treatment. Its effects are also variable on different people, some describing it as making them feel relaxed and 'dreamy', while others find it therapeutic and making them feel better in themselves.
Kava kava should not be taken without your doctor knowing about because there have been concerns about its effect on the liver if taken in excess. A European-wide ban was lifted about two years ago after testing found the risks of taking it to be very low. It has been used for centuries as an intoxicating drink on islands such as Fiji. Passion Flower
Through the intervention of GABA, passion flower extract helps in reducing anxiety levels and makes you feel a lot calmer. If you suffer forms of depression that make you hyper or excitable, passion flower will help to reduce this and also helps to cure insomnia. It is a component of many natural sleeping pills. These are just three natural substances that can be used to treat depression. However, you must inform your doctor or physician if you decide to take them since they may interfere with or change the effect of any antidepressant drug you are currently taking.
Call today for natural remedies for depression
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2207) Bromelain Supplements why?
Date:
November 06, 2010 10:32 AM
Bromelain Enzyme SupplementBromelain enzyme is a proteolytic digestive catalyst that contains sulfur. From the word “proteolytic”, this substance aids in the digestion of proteins especially when taken with meals. On the other hand, when taken without meals, it is deemed to act as an anti-inflammatory supplement. Ananas comosus or the pineapple plant is the best source of this beneficial enzyme. However, fresh pineapple extract does not contain doses high enough to have a medicinal effect. Hence, a preparation to meet the body’s demand is produced. Bromelain supplements now come in the form of tablets and topical creams. They are now widely available and affordable to counterweigh the several uses it offers. In the Digestive System, bromelain enzyme does not only help in digesting proteins but may also relieve gastric upset and heartburn especially when used together with other digestive enzymes like amylase, a catalyst responsbile for carbohydrate digestion, and lipase which is for the digestion of fats. Diarrhea conditions associated with deficiency in the proteolytic enzymes can also be alleviated with the use of this supplement. In the Immune System, bromelain has been widely considered as an effective relief for pain and swelling caused by both injury and certain infections. Studies frequently show the bromelain’s ability in facilitating the body to restore health more quickly. The mechanism is said to be a reduction of fibrin and leukotriene accumulation, thus regulating the inflammation process. Researchers have demonstrated evidences that a daily intake of 1,200 to 1,800 mg of bromelain may help alleviate painful inflammation just like in rheumatoid arthritis.
In the Cardiovascular System, bromelain supplement is theorized to play a role in the prevention of heart disease caused by atherosclerosis or thickening of the arterial wall due to plaque deposits. It slows down the clumping of platelets thus preventing a possible heart attack.
Bromelain May Also Relieve PainLastly, bromelain may also relieve pain associated premenstrual syndrome and menstraul cramps. Studies reveal that they act as prostaglandin inhibitors. However, bromelain can also increase the bleeding during menstruation. Bromelain supplement has no Recommended Dietary Allowance but doses of up to 1 gram taken 3 times a day showed no toxic effects. Experts also advise to take bromelain on an empty stomach supplemented with magnesium to increase the bromelain’s effects. Just like any other drug or food supplement, bromelain also has side effects, nonlife-threatening to be exact. It may have drug interactions such as increasing the absorption of some medications like antibiotics, chemotherapeutic drugs and specific antihypertensive agents. In addition, it may also bolster the effects of blood thinners such as warfarin (Coumadin), anti-inflammatory drugs and antiplatelet agents such as clopidogrel (Plavix). Since bromelain supplement can cause certain drug interactions, it is important to take this enzyme cautiously or under the supervision of a qualified health care provider.
To find quality bromelain supplements, look to your local or internet vitamin store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2193) Hops and St. John's Wort
Date:
July 15, 2009 12:17 PM
St. John’s wort has emerged recently as an herb that is known to assist the nervous system. Quite a few naturopathic physicians rank kava kava, valerian, St. John’s wort, passionflower, and hops as the most effective herbs for treating insomnia. A study that took place in 1994 and was published in the Journal of Geriatric Psychiatry and Neurology proved that St. John’s wort extracts increased deep sleep during the total sleeping period of the patients. This study also makes an interesting connection between sleep and depression. It was found that many standard antidepressants and MAO inhibitors used to treat those people who suffer from depression cause a decrease in deep sleep. St. John’s wort has demonstrated the ability to treat both insomnia and depression. Hops, an herb that is commonly found throughout the world, was originally used as a food. The tips of the food were both cooked and eaten. The young plants were the ones eaten because the older plants were too tough. A famous herbalist, Gerarde, recommended using the buds of these plants in salads, while the Romans anciently used hops as a food and Native American tribes found hops to be of great value. Hops have been appreciated for a long time for its nervine properties. A hop was first used as a beer ingredient in England around 1500. At this point, hops farmers noticed that their farmhands often seemed tired and easily fatigued. With time, the herb gained a huge reputation as a natural sedative. Pillows were filled with hops to promote rest and relaxation during the reign of King George when people were recovering from an illness. Lupulin is a compound that is found in hops. It is described as a sedative and hypnotic drug. Certain parts of the plant have been found to have sedative and hypnotic effects. This herb is known to be fast-acting, soothing, and calming to the nervous system. Additionally, it is another nervine herb that assists in promoting sleep. It is mainly used to alleviate nervous tension and promote restful sleep. Also, hops is used for antispasmodic effects. Its relaxing effect has the potential to calm the nerves and muscles in cases of muscle spasms. This herb has also been shown to contain appetizing and tonic properties. It acts as a stimulant to the glands and muscles of the stomach, while calming the hyperexcitable gastric nerves. Hops also has a relaxing influence upon the liver and gall duct, and a laxative effect on the bowels. Along with other uses, hops is also used for its antibiotic properties. It is very helpful for sore throats, bronchitis, infections, high fevers, delirium, toothaches, earaches, and pain. A hops remedy is a great way to help with inflammation, boils, tumors, and swelling. Hops is extremely high in B-complex vitamins, which are known for their calming effect on the nervous system. B vitamins also promote energy and aid in problems of depression, anxiety, nervousness, and memory. Additionally, hops is extremely rich in potassium, which is necessary for nerve transmission, contraction of muscles, and hormone secretion. Low levels of potassium are often found in those people who have high blood pressure. Additionally, hops contains magnesium, zinc, copper, iodine, manganese, iron, sodium, and fluoride. Hops and st. johns wort are a wonderful herb that has many therapeutic uses. Hops and st. johns wort come in tea bag, capsule, and tablet forms at your local or internet health food store. For more information on St. John’s wort and hops, contact your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2032) Digestive Essentail Enzymes
Date:
January 04, 2009 10:29 AM
Years of researching various health-promoting herbs, vitamins, minerals, and other dietary supplements has led to the conclusion that enzyme therapy is one of the most valuable ways to maintain and promote good health. Not very many of us actually understand the enormous role that enzymes play in health maintenance, with many of us actually being enzyme depleted due to the over-consumption of cooked enzyme-less foods and the under-consumption of raw whole foods. The human digestive system was designed for a diet that is full of raw plants and fruits, but many foods today are processed, refined, heated, and fragmented. By eating foods that have lost their own natural enzymes, the pancreas and other organs that supply digestive enzymes are over-worked. This results in enzymatic function in other areas of the body to become compromised, which leads to disastrous health implications. Replenishing enzymes through diet and supplementation is an easy way to make up for the typical diet that is full of mostly dead foods. The human digestive system is one of the most perfectly designed systems in the body, typically functioning without problems. This means that if we are eating the right foods in the right way, then we should not have to rely on antacids, H2 antagonists, proton-pump inhibitors, and laxatives. Burping, belching, and bloating, no matter how often they occur, are actually not normal. It is ironic that the human body has a system that is far more impressive than any other machine built by humans, but we suffer from breakdowns all the time such as abdominal cramps after eating, inordinate amounts of gas, sluggish colons, and an overall lousy feeling after eating. Statistics prove that we are not eating the right foods, and even if we were, many of us are not properly absorbing all of their nutrients because we consume huge amounts of sugar, drugs, caffeine, alcohol, and highly processed refined foods that prevent normal digestive processes. Being under constant stress and eating on the run, along with our unhealthy food choices, creates an environment inside our body that causes common cases of heartburn and indigestion, possibly leading to ulcers and colon disease. Enzymes are protein molecules that are responsible for thousands of physiological reactions that take place in the human body. They initiate and control almost every biochemical process that occurs in the body, with nearly three thousand individual enzymes being identified to date. Enzymes help our body to digest food, repair tissue, and eliminate dangerous toxins. Digestive enzymes break down food particles, which allows them to pass through the intestinal wall and enter the bloodstream. The enzymes that are found in the blood transform nutrient particles into tissue that is found in muscles, nerves, organs, and glands.
Enzymes also contribute to the process that stores sugar in the liver and muscle tissue and preserves fatty tissue. Additionally, digestive enzymes are part of the chemical reaction that creates urea. Some enzymes even help to detoxify our blood and tissue by allowing our immune system to attack foreign material. Lastly, metabolic enzymes help create energy in our body on a cellular level by converting foot to energy, which then fuels nearly every mechanism in the body. Do you get enough enzymes on a daily basis?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1957) Horny Goat Weed
Date:
December 06, 2008 10:05 AM
Horny Goat weed, correctly named Epimedium, or Yin Yang Huo in Chinese, is one of over 60 herbaceous plants of the Berberdaceae family. It grows naturally in Southern China, and also in Korea, Southeast Asia and some parts of Europe. Other names given to include Fairy Wings and Bishop's Hat. Horny goat weed has been viewed as a natural alternative to Viagra, and many species of Epimedium are said to possess aphrodisiac properties, and is said to have got its name from a Chinese goat herder who notice that his goats became more 'frisky' with the lady goats after eating the plant. In fact studies have indicated to increase vitality, particularly the libido and male sexual vitality, although it also possesses some other health benefits in its effect on dementia and osteoporosis. The term 'horny' is used in the colloquial sense, and has nothing to do with the shape of the plant, the flowers of which are star-shaped. In fact the Chinese name for it means 'licentious goat weed', making the English translation quite clear. The main ingredient in horney goat weed is icariin, a flavonoid glycoside that acts as a PDE5 inhibitor. Others include the similarly named, but totally different chemical, icaritin, and also many other that will be discussed later. It is icariin on which we shall focus for the time being. Since this is central to its effect on erectile dysfunction, some time will be spent on explaining what PDE5 inhibitors do. cGMP (Cyclic guanosine monophosphate) is a chemical that relaxes smooth muscle tissue, including the vascular smooth muscles in blood vessels. This can lead to the dilation, or increase in size, of blood vessels and increased blood flow. The corpus cavernosum of the penis is a spongy area that runs the full length of the penis, and contains many blood vessels that can be dilated through the action of cGMP and allow the increased blood flow to create an erection. PDE5 (phosphodiesterase type 5) is an enzyme that can degrade cGMP and prevent the relaxation of these blood vessels, and so prevent them from dilating. A PDE5 inhibitor, such as icariin, prevents the PDE5 from degrading cGMP, and so allow a normal erection. Sidenafil, commonly known as Viagra, is a similar PDE5 inhibitor and works in the same way as icariin. Hence, the effect of Viagra is not to create an unnatural erection, but in fact to allow the cGMP to do its natural work by preventing the phosphodiesterase from stopping it doing so. This is just one of the effects of horny goat weed: it is a more natural PDE5 inhibitor than Viagra is. It is also more specific than Sidenfil, and does not interfere with any of the other phosphodiesterases that are essential for other purposes. However, its effects do not stop there, because icariin possesses other properties, and is also only one of the many components of epimedium that can increase vitality. Among these are a number of flavonoids in addition to icariin, sterols and the isoquinoline alkaloid magnaflorine, that possesses antioxidant properties and reduces LDL cholesterol. The exact mechanism by which horny goat weed works to increase sexual desire is unknown, but it is believed that it inhibits the enzyme acetylcholinetsrase (AChE). Cholinergic synapses are the spaces between brain cells that allow electrical impulses to be transmitted, and are an essential component of neuromuscular system response to stimulation. AChE can stop these from working properly, and prevent neurotransmitters from effectively allowing sexual arousal. Horny goat weed can inhibit the activity of this enzyme and allow the neurotransmitters such as serotonin, dopamine and norepinephrine to do their proper job in allowing sexual arousal to occur. This, again, is a natural and not a chemical solution. It has also been found to reduce cortisol levels that cause stress which also reduces sexual desire. The effect of Epimedium on smooth muscles can also aid those suffering from pulmonary hypertension, in which the small blood vessels in the lungs become too narrow to be effective in allowing the transfer between oxygen and carbon dioxide. PDE5 inhibitors can help these blood vessels to relax and so be more easily dilated in the same way as those in the corpus cavernosum. Once dilated, they are able to carry more blood to and from the lungs and allow the reoxygenation process to continue smoothly. Research has also discovered the possibility of horny goat weed possessing monoamine-oxidase inhibition properties. Monoamine oxidase enzymes can deaminate hormones such as dopamine, and can significantly reduce the production of testosterone. The inhibitor prevents this happening, and leads to elevated levels of dopamine, and also of serotonin and noradrenaline. Dopamine encourages the pituitary gland to release luteinizing hormone that in turn promotes the production of testosterone by the testes. Another property of horny goat weed is that it can protect against the toxin beta-Amyloid, a protein that damages DNA in the brain, causing the death of brain cells and the accumulation of dead cells in your brain. This in turn leads to dementia and potentially Alzheimer's disease. The use of Horny goat weed is being studied closely in relation to this property. The active ingredient here is icaritin (not to be confused with icariin) Epimedium also has implications in the treatment of the cartilage and bone damage that occurs with arthritis and osteoporosis. It is possible that this is connected with the antioxidant and anti-inflammatory properties of magnaflorine, and icariin has been found to have bone-healing properties. It is known that damaged cartilage treated with horney goat weed displayed signs of growth and regeneration when compared to a placebo. However, the most popular use of horny goat weed is in its effect on the libido and erectile dysfunction. The effect on the libido and sexual desire works equally well for men and women, and it is a preferred natural remedy to synthetic equivalents such as Viagra, Levitra and Cialis. The added benefits of the natural product render epimedium the preferred and safest solution for many people.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1945) Gymnema Sylvestre
Date:
November 12, 2008 09:51 AM
Gymnema sylvestre is found naturally in central and southern India, where it has been used in traditional Indian medicine for almost two thousand years. It is known as 'gurmar' in ancient Indian texts, a word meaning 'sugar destroyer', which gives an indication of its uses in medicine. It is used to reduce the absorption of glucose into the body, and also reduce the sweetness of foods, both of which are desirable for those wishing to lose weight and to reduce the level of sugar in their blood. It was used for this purpose in Ayurvedic medicine, subjects being given the leaves to chew. As with many other ancient Ayurvedic remedies, this use of gymnema sylvestre has passed into modern times, and has sound scientific basis. First, however a bit more about the plant itself. It is found predominantly in the Western Ghats, and also to the west of the mountains, around coastal Goa. It is a vinous plant that climbs on other bushes and trees, known in Sanskrit as Meshasringa, or ram's horn after the shape of the leaves from which the supplement is extracted. For what it's worth, the official name seems a mix of Greek and Latin (gymnos(Gr) - naked and Silva (L)- forest) for naked forest. That, however, is irrelevant to its uses, so let's have a look at the science involved and the active ingredients in the plant. The main constituents are terpenoid saponins known as gymnemic acids, so one can assume that they were first found in this plant. They are glycosides, including hodulcine and ziziphin, which act as sweetness inhibitors so that there is no sweet taste in anything that is sweetened by sucrose. There are over 20 types of gymnemic acid in the leaves, of which the strongest, Gymnemic Acid 1, can suppress the sweetness even of artificial sweeteners such as aspartame. These are not irreversible effects, and last only about 10 minutes, after which normal sweetness is detectable by your tongue. During the active period, however, a solution of normal sugar will taste like ordinary unsweetened water. However, is this just a matter of taste, or does it affect the sugar itself? Studies have shown that animals fed the leaves of Gymnema sylvestre develop hypoglycemia, probably because it stimulates the pancreas to generate insulin that reduces the level of sugar in the blood. Further studies have shown the presence in the leaves of a number of types of acylated derivatives of deacylgymnemic acid. There are well over a dozen types of saponins known to be contained within the leaves. Other chemicals found include anthraquinones, flavanoids, chlorophylls, querticol, phytin, a number of glycosides and anthraquinones. The bush also contains alkaloids, although these are constituents in most plants used in ancient remedies. This is by no means all of the chemicals discovered, and many of the minor benefits of using it could be due to the minor constituents of this amazing little leaf. A study of the above constituents will reveal a few antioxidants, and it is no surprise that the extract from Gymnema sylvestre also possesses anti-inflammatory properties. Gymnemic acid is believed to have a similar chemical structure to saccharose, and the plant extracts can be used not only to reduce a craving for sugar, but also to treat digestive problems and high cholesterol levels. So what scientific evidence is there other than the obvious effects reported by those that use it? A study in the UK in 2005 found that an aqueous extract of Gymnema sylvestre caused the secretion of calcium and insulin from mouse and human cells to be increased at a specific concentration without affecting the cellular function. This means that the supplement can be used to stimulate the secretion of insulin with people with Type 2 diabetes without otherwise affecting health. Its usefulness to diabetics is obvious, but there are other health benefits to those that are not diabetic. Anything that modulates a sweet tooth must be of use to those seeking to lose weight, particularly if they feel the need for sweet foods. In fact Gymnema tends to reduce food cravings for carbohydrates and sweets, and can be used by those seeking a natural means of curbing their appetite for sweet and sugary foods. Because excess weight can lead to diabetes, Although there have been many discussions about the biochemical mechanism of the gymnemic acids in this effect on taste, recent evidence suggests that the phytochemicals act on both your taste buds and on those parts of the intestine responsible for absorbing nutrients from digested foods. Not only that, but studies have also indicated that Gymnema sylvestre removes the bitterness of acerbic chemicals such as quinine in the same way that it removes the sweetness form cakes and candies, and if you drank tonic water it would taste just like water. On the other hand, if you ate an orange, you would taste the acidity but not the sweetness. The way to use this remarkable supplement is to follow the instructions, and within about a week you will be able to control your appetite much better, and any cravings for carbohydrates you previously had will be much reduced. After a month or so, you will notice an accelerated rate of weight loss if you had been overweight, and diabetics will find a significant reduction on blood sugar between insulin shots.
Gymnema sylvestre can take care of any sugar or carbohydrate cravings, and is of significant use to the overweight, obese or to diabetics, and the mechanism by which it works has now been all but understood, although there are still some biochemical secrets that this amazing plant has yet to reveal. This amazing herb can be found at your local or internet vitamin store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1935) Garlic
Date:
September 01, 2008 01:04 PM
Garlic is a member of the lily family, related to onions and chives, and offers many health benefits other than deterring vampires. There is now ample scientific evidence and proof of its beneficial effect on both a healthy immune system and the circulatory system. The active ingredients in garlic are thiosulfinates, of which the predominant one is allicin, sulfoxides such as alliin and dithiins, of which ajoene is the most widely researched. These compounds are not only responsible for the pungent odor of garlic, but also for its benefits to your health. Among the other components of garlic are selenium, manganese and vitamins B6 and C. Before considering the other effects of garlic on your health, we shall first consider how it benefits the immune system. The immune system is an essential part of human biology, and protects your body from invasion by pathogenic organisms. Without the immune system your body would rapidly be overcome by bacteria, viruses, fungi, parasites and other foreign bodies, and your body would rapidly fail to function. The immune system consists of several components that can act in concert to protect you from these foreign invaders. It is too large a subject to be discusses in this article, although its major components are the thymus, the spleen, the lymphatic system, bone marrow, antibodies, and white blood cells of various types. Without it your body would rapidly be broken down to nothing, and would revert to a skeleton in a few weeks. It is your immune system that causes inflammation, fevers, boils and pus. These are all examples of the immune system at work to protect your body, and even a fever is the immune system raising your body temperature to one that is unfavorable to invaders. Arthritis and hay fever are other examples of how your immune system reacts to invaders, in one case mistaking damaged joint tissue as being foreign and responding by causing inflammation to protect the joint, and in the other a reaction to invading bodies such as pollen. So what does garlic do to help your immune system? Let's first have a look at the inflammatory reaction of the immune system, a prime example of which is rheumatoid arthritis. The inflammation is caused by compounds known as prostaglandins and thromboxanes, the biosynthesis in your body of which requires the enzymes lipoxygenase and cyclooxygenase (LOX and COX). If these enzymes can be inhibited, then the inflammatory response can be modulated, and LOX and COX inhibition is one of the studies currently being carried out into the treatment of some forms of cancers. However, where garlic comes in here is that two effective non-reversible inhibitors of LOX and COX are the chemicals Di(1-propenyl) sulfide and ajoene, and both of these are components of garlic. Garlic can therefore be used, not to stop the inflammatory response altogether since it is an essential part of the immune system for certain infections, but to modulate it and protect you from the more severe effects of conditions such as arthritis - both osteo and rheumatoid - and asthma, which is also an immune response. Allicin has been shown to work with vitamin C to kill certain types of bacteria and viruses, and can help the immune system to protect you from colds and flu, Candida and some gastroenteric viruses. It can also be effective against some of the more powerful pathogens such as tuberculosis. It should be stressed that garlic will not cure these conditions, but help the immune system to deal with them. In fact with respect to the common cold, a study at Munich University has shown that garlic significantly reduces the activity of kappa-B, which is a nuclear transcription factor that mediates the inflammatory response. In other words, the cold symptoms are greatly reduced. This is significant, since increased kappa-B levels can be triggered off by any pathogen that causes an inflammatory response by the immune system (e.g. infection, allergens, physical trauma). The study showed that unfertilized garlic provided a reduction of 25% in kappa-B activity, while garlic fertilized with sulfur reduced it by 41%. There have been other studies carried out that demonstrated that Helicobacter pylori, the organism responsible for gastritis and peptic ulcers, was less active in those that took a regular amount of garlic in their diet. This was shown by measuring the antibody concentration, and while H.pylori was found in both sets (with and without garlic in the diet), the antibody count in the garlic-eating set was much lower indicating a significantly lower population of the bacterium. Another unexpected result was that a group taking both cooked and uncooked garlic had a lower antibody count than those taking either cooked or uncooked. This appears to indicate that cooking changes the chemical nature of garlic, so that both forms work together to provide a more potent effect that cooked and uncooked separately. What has also been established is that odorless garlic has less of an effect on the immune system that natural garlic, so while the odorless type is more socially acceptable, it is not so good at supporting your immune system. The allicin levels in odorless garlic are very much lower than in the natural bulb. Garlic has also been found to be able to help with certain types of cancer. Two servings weekly have been found effective in protecting from colon cancer. Allicin has been found to protect colon cells from the toxic effect of various chemicals, and also reduce the growth rate of any cancerous cells that develop. People in Southern Europe consuming large quantities of garlic have been shown to be 39% less liable to contract cancer of the mouth and pharynx, and 57% less liable to contract cancer of the esophagus. It also had an effect on other cancers, including breast and ovarian cancer. However, the effect of onions on such cancers is even greater. Most people are aware of the cardiovascular benefits of garlic, and it can reduce blood pressure, cholesterol levels and serum triglyceride levels, thus protecting against the harmful condition of atherosclerosis and also of diabetic heart disease. Reduced atherosclerosis means a reduced chance of heart attacks or strokes. It also appears to possess antioxidant properties.
There is no doubt that garlic helps to promote a healthy immune system, although the odorless form appear to be less effective in this respect as natural garlic, and there is evidence that a diet containing uncooked and cooked garlic can be more effective than either of these alone.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1879) Red Yeast Rice
Date:
August 04, 2008 04:07 PM
Many natural substances that are capable of lowering blood fats and cholesterol levels that are potentially harmful have emerged. No one is suggesting that there is a magic pill that will promote healthy cholesterol levels, but nature has provided us with some specific compounds that are capable of enhancing both dietary and lifestyle changes in order to improve cardiovascular health. One of the most impressive of these compounds is that of red yeast rice, which is a fermented food substance that has been traditionally used for its red-coloring abilities in meats and other foods. Additionally, red yeast rice offers some extremely beneficial therapeutic effects, as it is the source of certain compounds that can successfully reduce cholesterol. Pharmaceutical companies have been making cholesterol lowering drugs for many years, but natural supplements are now available which offer the consumer a way to lower cholesterol in natural way. This is extremely good news for those people who are suffering from moderately elevated cholesterol levels and is looking to avoid synthetic drug preparations and the side effects that follow. Most of us are now aware that high serum cholesterol level is what predisposes us to cardiovascular disease along with other degenerative conditions. Learning how to control our cholesterol levels, especially the LDL and blood triglyceride levels, while keeping HDL cholesterol at desirable levels can be an extremely frustrating task. By decreasing our consumption of animal fats and certain types of oils, eating more fiber and taking prescription drugs or natural alternatives, we can easily accomplish our goal. Dietary changes should be targeted first, but turning to cholesterol-lowering prescription drugs has both its pros and cons. Pharmaceutical preparations come with considerable side effects. Some of the drugs that are most effective contain enzymatic inhibitors that prevent the synthesis of cholesterol. Red yeast rice accomplishes the same enzyme inhibition but is considered a natural alternative that safely promotes healthy serum cholesterol levels. Coronary heart disease refers to the damage that is done to the heart when the coronary arteries become blocked or narrowed because of a buildup of plaque or oxidized cholesterol. When cholesterol buildup breaks off and lodges in the heart or brain, this causes a heart attack or stroke. An extremely common disorder of developed nations, coronary heart disease causes more deaths in the US than any other disease. Many people who die from heart disease are ironically in otherwise good health. High blood pressure, which is a related disorder, is similar in the fact that both can be a silent killer. The symptoms of coronary heart disease include impotence, heart attack, or stroke. Although the mortality rates from coronary heart disease have declined over the last twenty years, the reason for this decline is shown to be the better medical technology that is available. Claiming more than one million deaths every year, coronary heart disease is still a major issue facing the American society.
In order to help us prevent heart disease, we have been given many dietary guidelines. However, many of us are not motivated enough to make the dietary changes that could literally save our lives. The major causes of coronary heart disease include obesity, smoking, alcohol, high protein and high saturated fat diet, lack of exercise, high blood pressure, high cholesterol levels, and a genetic predisposition.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1852) Bromelain Enzymes
Date:
May 01, 2008 02:45 PM
Bromelain consists of two enzymes that digest proteins, otherwise known as proteases or proteolytic enzymes. These enzymes are obtained from different parts of the plant, one from the stem and the other from the fruit. It also includes protease inhibitors, acid phosphatase, peroxidase and calcium. First used as a supplement in 1959, bromelain is particularly popular in Germany, where a lot of the recent research has been carried out. Because the stem enzyme is in the greatest amount, eating pineapple will not give a great deal of bromelain, and you will have to take the supplement which is extracted from the stem in order to get the greatest benefits. Bromelain has several therapeutic effects on the body, and is a good aid to digestion. The enzyme can boost the digestive processes and so reduce the incidence of problems such as heartburn, acid reflux and any other condition caused by the incomplete digestion of foods. It does this by breaking down proteins so they are more easily digested. In fact its potency is sometimes measured in GDUs (Gelatin Digesting Units), gelatin being a common protein that is easily used for the measurement of bromelain activity. It is also measured in MCU (Milk Clotting Units), since bromelain can also be used to clot milk, and a standardized dose should contain 2 MCU per milligram. The dosage to use depends a great deal on the condition being treated, but a good general average for digestive problems is 500 mg three times daily. Bromelain works best at an optimum pH of 4.5 – 5.5 and can therefore help to balance the pH in its environment. It is extremely important to the immune system that the pH of the body is balanced and controlled to within certain limits, and bromelain can help to achieve that. In helping to reduce the excessive acidity caused by poor digestion, a balanced pH of the stomach is also maintained, helping to reduce the feeling of nausea, common with some digestive defects. The overall result of bromelain supplement is to help to maintain a better digestive system and ease the discomfort of many people for whom a meal is frequently not the pleasure it should be. Bromelain is also an anti-inflammatory, and used for temporary relief of the inflammation caused by surgical procedures, arthritis and various injuries and forms of disease It is commonly used for the treatment of sports injuries and also immediately after surgery to reduce the risk of inflammation. It appears to have an inhibiting effect of the production of pro-inflammatory metabolites in the body, although the mechanism by which it works is not yet fully understood. In fact many of the therapeutic benefits of bromelain have been show to be only partially due to its proteolytic activity, and it is now believed that there are also as yet unidentified non-protein factors present in bromelain that contribute to these forms of health benefit. The biochemistry of bromelain has yet to be fully characterized. Notwithstanding that, the substance has been recommended for the treatment of a wide range of connected conditions, such as gout, arthritis, hemorrhoids, ulcerative colitis, autoimmune disorders, hay fever and sinusitis. It is particularly useful where there is pain, where tissues have become swollen and when tissue repair is needed. It appears to inhibit pain-inducing prostaglandins and is also believed in some way to induce the biochemical production of other prostaglandins that have an anti-inflammatory effect. All of this knowledge has come as a result of studies carried out on the biochemical activity of bromelain, but have not yet been proved and is indicative of the lack of biochemical knowledge on this substance and the chemicals it contains. What have been demonstrated, however, are its effects on platelets and blood clots in arteries. It appears to do this by the inhibition of the formation of high levels of fibrinogen from which clots are made, and also inhibits the aggregation of blood platelets and their ability to stick to the endothelial cells of blood vessels, particularly the arteries. The fibrin that is produced from fibrinogen not only promotes blood clotting but is also associated wit the retention of fluid. It is a protein, and the proteolytic effect of bromelain also breaks this down. Bromelain therefore works in a number ways to reduce fluid retention, prevent blood clotting and inhibit the aggregation of blood platelets on artery walls. The measurable effect of this is the thinning of the blood that such activity promotes. It is logical that if fibrin contributes to the viscosity of blood, then its destruction will result in thinner blood, and hence lower blood pressure. It is also used in the treatment of burns, where it helps to remove the dead skin that can delay recovery after third degree burns. It also appears to promote the absorption of many antibiotics, which again helps in recovery. Bromelain is relatively safe to use with few side effects, although, curiously, among the side effects are some conditions it is also used to treat. Among these are nausea and allergic reactions, along with diarrhea and excessive menstrual flow. One of its successes has been in the control of menstrual pain. Bromelain has been proposed for cancer therapy, its potential use being recommended due to its effect of the adhesion of cells, its regulation of the immune function and its effect on the immunosuppressive cytokine TGF-beta that is involved in several types of cancer and their metastasis (spread to other parts of the body). However, a lot more work is needed on this for definite conclusions to be drawn. On a more practical note, the effect of bromelain on proteins is put to use as a steak tenderizer. If the product is sprinkled in powdered form onto meat, and then forked into the tissue, the enzymes will break down the protein of the meat and make it tender when cooked. However, don’t overdo it or you will end up eating a meaty mush more akin to a soft meatloaf than a good steak!
All in all, bromelain is a useful supplement for many medical conditions, and does to food in your stomach what it does to steak on the plate. It is generally used in supplement form because the active enzyme is not in a high enough concentration in the fruit itself, but in the stem from which it is extracted after the fruit has been harvested. It is also easier to standardize a supplement than a fruit.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1779) Don’t Live With Pain, Live Pain Free – Curamin Is The Answer
Date:
April 24, 2008 04:32 PM
Fact, more than 50 million Americans suffer from chronic pain. Chronic, meaning pain that continues daily, weekly, monthly, and yearly, pain may which never end with out help. According to the Journal of the American Medical Association, pain is the primary reason people seek the advice of a doctor or health practitioner, and the number one reason people take alternative medicine. A new revolutionary dietary supplement for pain and inflammation is now available on the market. Introduced by Terry Lemerond, this new formula called Curamin has changed thousands of lives. This formula contains three anti-inflammatory herbs and one amino acid that can help one live a more normal pain free life. The first ingredient: Curcumin is a substance found in turmeric. Curcumin contains curcuminoids which have been shown to reduce inflammation and pain. Turmeric is an ayurvedic herb discovered in India and brought over to the United States has demonstrated amazing results. Turmeric has been cooked with and used as a medicine for over 2000 years. The active ingredient in turmeric is curcumin which has demonstrated six important properties. Curcumin has anti-inflammatory, antioxidant, antiviral, antibacterial, antifungal, and anti-cancer properties. As you can see this herb has made quite a name for its self. The second ingredient is Boswellia. Boswellia contains boswellic acid which is the active ingredient in this herb as well. This herb has also demonstrated its natural ability to fight inflammation and more. Research suggests that Boswellia’s active ingredient can actually modulate the expression of the genes involved in the body’s inflammation response thus giving itself an anti-inflammatory name. The third ingredient is DLPA an amino acid also known as DL Phenylalanine. This amino acid can help the body product more serotonin in the brain. D-phenylalanine can actually help reduce chronic pain through the production of serotonin. Serotonin helps one feel more relaxed and level headed this is something everybody needs when it comes to pain that drives them crazy all day long. Those people consuming MAO inhibitors and anti-depressants need to avoid DLPA with out a doctor’s supervision. The forth and last ingredient in Curamin is nattokinase. Nattokinase is an extract from fermented soy cheese. For thousands of years natto has been consumed by the Japanese people with out even know the health benefits of its consumption. Nattokinase can help the body fight blood clots, thin the blood, and fight pain and swelling. This new formula Curamin has the three top herbs that fight inflammation in the body, when combined with DLPA, this product has the amazing ability to fight pain by attacking the source of pain, inflammation. Recommended doses for curamin are 2 capsules in the morning and 2 more capsules in the evening after work. Some may need a stronger dose at first, this is where one should take 4 capsules at one time in the morning for the first few days then step back to 2 in the morning and 2 in the evening. We have free samples available upon request and back the curamin product with a 100% satisfaction guaranteed. So if you are un-satisfied, just return the unused portion of the product for a full refund of the purchase price minus shipping costs. So what are you waiting for? Are you ready to live pain free? Give curamin a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1770) The Prevention and Treatment or Prostate Cancer
Date:
April 10, 2008 01:36 PM
Last week I shared with you the controversy surrounding the use of PSA screening to determine the status of the prostate. There are many doctors who do not believe that using PSA is accurate enough to rely on for determining whether or not a high PSA indicates prostate cancer. Many men, who have a high PSA, after more detailed examination, did not have cancer and men with a low PSA did have cancer. Some physicians do not believe that the current methods of diagnosing prostate disorders are saving lives. Also, there is a group of physicians nationwide that strongly believe the best treatment is no treatment but rather a “watch and wait” approach. Prostate cancer usually is slow growing and more than 70% of men who develop it are over 65. The older a man is, the more likely he is to die of some other condition before his prostate cancer becomes a real threat. To reiterate, the American Cancer Society states, “at this time watchful waiting is a reasonable option for some men with slow growing cancers because it is not known whether active treatment such as surgery, radiation therapy or hormone therapy prolongs survival”. So what action can be taken? While prostate enlargement (BPH) is not related to prostate cancer, it can elevate PSA scores and can cause symptoms in 50% of men by age 80 and nearly all will show signs of BPH by age 85. If you have early symptoms of BPH such as frequency of urination, a burning feeling after urination and the caliber of stream that isn’t what it used to be, getting up several times through the night and low back pain, taking a good prostate support formula will be your best treatment and prevention. Most men will notice a remarkable improvement within a few weeks. A good prostate support formula will provide relief for 80-90% of all men from these annoying symptoms. But what about prostate cancer? The best cure for prostate cancer is prevention. I’ll give you a complete supplement program for prevention but first what about PSA testing? “I don’t believe in screening for something when it’s too late. By the time cancer develops a positive mammography or a true high PSA are likely too late, or if fortunate, that particular cancer will not be a problem. It makes far more sense to prevent the problem in the first place. And there is clear data, prevention is possible”. Dr. Robert J. Rowen, MD, Second Opinion, Soundview Communications. My recommendation, based on research of several scientific studies, includes various nutritional supplements and herbal extracts. Following are several very important studies that all men should be aware of. In 1966 Dr. Larry Clark of the University of Arizona published startling data suggesting that prostate cancer could be reduced by as much as an amazing 60% by supplemental yeast derived selenium, 200 mcg per day. Selenium is a powerful antioxidant and participates in key and crucial detoxification and free radical scavenging enzymes (80-90% of all disease is caused by free radical damage and inflammation). Selenium is one of a number of antioxidants to prevent this free radical damage; In 1999 a New Zealand study published in the British Journal of Cancer documented a 40% lower incident of prostate cancer in men with the highest levels of omega-3 fatty acids EPA and DHA in their blood. These findings have been confirmed in other omega-3 fatty acid studies. Conversely, another published report documents a high level of omega-6 to omega-3 fatty acids in invasive prostate tissue samples. Taken together with recent reports on high levels of omega-6 fatty acids (soy, sunflower, safflower, peanut, corn and most vegetable oils) linked to breast cancer, a common thread emerges. The American diet is overwhelmed with omega-6 oils. Excessive use of omega-6 fatty acids are cancer causing and also cause inflammation. Trans fatty acids from hydrogenated oils seriously add to the problem. There are other nutrients that have shown to reduce prostate-cancer risk. Vitamin E and lycopene have also shown to prevent prostate cancer. Lycopene is commonly found in tomatoes, especially cooked tomatoes. If you like spaghetti sauce or salsa, this is a great way to fight prostate cancer. While vitamin E, selenium, lycopene and omega-3 fatty acids are all great prostate supporting nutrients, through research I found a much more powerful combination of food grade molecules that can prevent and treat cancer. Extensive research in the last few years has revealed that regular consumption of certain fruits and vegetables can reduce the risk of prostate cancer. Fruits and vegetables having the highest degree of prostate cancer protection are the following: grapes (resveratrol), garlic, tomatoes, hot peppers, turmeric (curcumin), ginger, berries, milk thistle, cloves and fennel. These foods are protective because they are extremely active and excellent antioxidants. My favorite is turmeric (curcumin) because not only is it an antioxidant, it is also an anti-inflammatory agent. When it has this dual effect it is many times more potent than other types of food. In the United States there is 30 times more prostate cancers diagnosed than there are in India where turmeric is consumed liberally in most of the Indian dishes. Cancer does not begin shortly before it’s diagnosed. The origin of cancer may be years or decades in the process before it is even diagnosed as such. It is a multi-step process that goes through various phases such as cellular damage and transformation and culminates in the acquisition of invasive potential angiogenic properties and establishment of metastatic lesions. This process, and probably rightly so for all cancers, can be activated by any one of the various environmental carcinogens (cancer causing); all forms of tobacco products, industrial emissions, gasoline vapors, inflammatory agents, food coloring and preservatives, excessive UV rays, alcohol, hair dyes, cleaning products and drugs. The multi-step process of these cancer causing compounds progress in three stages; tumor initiation, promotion and progression phases. A powerful antioxidant/anti-inflammatory can prevent most if not all of the damaging effects when taken on a daily basis. Several population based studies indicate that people in Southeast Asian countries have a much lower risk of acquiring colon, gastrointestinal, prostate, breast and other cancers when compared to their western counterparts. It is very likely that constituents of their diet such as garlic, ginger, turmeric, onion, tomatoes, cruciferous vegetables, chili’s and green tea play an important role in their ability to avoid these cancers. These foods, or key active extracts from these foods, are known to block the NF-kB activation process. Also, several phytochemicals such as curcumin, resveratrol and green tea catechins have been shown to suppress AP-1. Several chemopreventative phytochemicals including curcumin, resveratrol and green tea have been recently shown to be powerful inhibitors of several growth factor receptors including EGFR. Curcumin also possesses the capacity to inhibit the activation of the EGF-Receptor indicating that it has the potential to break the autocrine loops that are established in several advanced cancers. Studies also suggest that curcumin, resveratrol and green tea can actually be used as safe, non-toxic treatments in drug resistant cancers. These natural phytochemicals (food grade) can help fight certain cancers thereby requiring a smaller dose of drug chemotherapy. They also can protect the body from the damages of drug chemotherapy and radiation. “This mini review presents evidence that chemopreventative agents, curcumin, green tea and resveratrol, can be used not just to prevent cancer but also to treat cancer. Because of their pharmacological safety, most chemopreventative agents can be used in combination with drug chemotherapeutic agents to enhance the affect at lower doses and thus minimize chemotherapy- induced toxicity. Because cancer is primarily a disease of old age, less toxic therapy is a major priority. This review reveals that molecular targets of chemopreventative agents are similar to those currently being used for the treatment of cancer. Tumor cells use multiple cell survival pathways to prevail and thus agents that can suppress multiple pathways have great potential for the treatment of cancer”1,2. Curcumin, resveratrol and green tea were as effective in preventing and treating certain cancers based on lab and animal studies. There have been approximately 20 human positive studies but much more needs to be done. From the research that I have done, I am convinced sufficiently enough to take many of these compounds as a preventative of cancer. These compounds are completely safe and non-toxic even in high doses. What does one have to lose? Why not take the positive preventative measure? –Compliments of Terry Naturally Ref: 1. Role of chemopreventaive agents in cancer therapy. Comprehensive Cancer Center Our Lady of Mercy Medical Center, New York Medical College, Bronx New York 2. Cytokine Research Section, Department of Bioimmuno Therapy, University of Texas, M.D Anderson Cancer Center, Houston Texas
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1748) Third- The Science (Putting It All Together) Boswellia & Inflammation
Date:
April 03, 2008 12:44 PM
Frankincense has traditionally been used in Ayurvedic medicine for centuries, and is even mentioned in the Bible. The trunk exudes a resin containing mono- and sesquiterpenes that possess powerful anti-inflammatory properties. They are also well known antiseptics and astringents, and support the immune and respiratory systems. These terpenes are commonly referred to as boswellian acids, and consist of a carboxylated pentacyclic triterpene with at least one more functional group. Both the alpha and beta acid have a hydroxyl (-OH) grouping, and there are also the acetyl (CH3CO-) equivalents with an acetyl group replacing the OH. There are other so-called-boswellian acids, and it is believed that they all play a part in the anti-inflammatory properties of the resin. The acetyl derivatives are thought to be involved in the death of some cancer cells, particularly those involve in brain and colon tumors, and also leukemia. The way in which they achieve this appears to be a programmed progression that ends with the dying out of the cells rather than a violently destructive mechanism, which lends credence to the Ayurvedic belief that the treatment is a natural one designed by nature. The anti-inflammatory properties of the acetyl triterpenes are due to their effect on leukotrienes that sustain the inflammatory reactions of many allergic reactions and also of asthma. They appear to inhibit the enzyme elastase in leukocytes; this is a crucial enzyme in the production of the chemicals that promote inflammation. It has been established that the inflammatory response of the immune system is due to the action of specific enzymes, so it stands to reason that if you can inhibit these enzymes, then you will also inhibit the immune response to specific initiators and so reduce the pain involved. Bosellian acid in the form of triterpenes appears to contain these inhibitors, and this would appear to explain its effectiveness. Pinene and phellandrene are among the terpenes isolated from Boswellia. A standardised dose of 60% - 65% of Bosellian acids is generally used, so if you are purchasing Boswellia this is what you should be looking for. Keep in mind that it is intended to treat inflammation, ands that inflammation is an indicator that something with your body is not quite right. Therefore, while inflammation is painful, and Boswellia may help, you should also treat the cause of the inflammation by treating the immune system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1741) Boost Skin And Joint Health With Natural Supplements
Date:
January 19, 2008 10:37 AM
A lot of health conscious adults are now attempting to keep a youthful appearance for as long as possible by exercising, taking growth hormone enhances, and using expensive cosmetics. However, studies have proven that the major signs of aging in the skin, joints, and eyes occur due to a progressive collagen and hyaluronic acid degradation in our tissues. Researchers believe that supplementation of these key nutrients can actually reverse sings of aging. Normal functioning of the skin requires that there be normal physiological substances in and around the skin cells. Of the many substances that are required for normal functioning, collagen is one of the most important. Collagen provides structural support to skin, which helps to maintain skin tone, subtleness and elasticity. All of these give the skin its amazing beauty. Without enough collagen, our body would actually lose any connective properties and its ability to hold together, causing the sagging and wrinkles that are associated with age. Hyaluronic acid is also a vital component of the skin's structure. HA is a big part of the space between living cells and is also present in both the dermis and epidermis, where it allows skin to retain moisture and acts as a lubricant between the collagen matrix of the skin. Younger looking skin typically has higher levels of HA, but it has been observed that hyaluronic acid content declines as we age, most dramatically after the age of 50. Most people after the age of 40 have already lost a lot of HA and may require supplementation. High concentrations of hyaluronic acid and chondroitin sulfate are able to reach the corium layers of the epidermis and provide cellar level nourishment to the skin. This then reveals a more vibrant and younger looking complexion. Doctors believe that osteoarthritis affects more than 20 million Americans, with that number reaching 40 million by the year 2020. Some doctors believe we're headed for an epidemic of degenerative joint disease. Osteoarthritis is a degenerative joint condition marked by the erosion of the cartilage at the ends of the bones. Cartilage is the shock absorber of the joint, with regular wear and tear on the joints eventually softening, fraying, and thinning the substance. Other things that can cause cartilage degradation and osteoarthritis have recently been identified by scientists, including: weak quadriceps muscles, eroding cartilage, and changes in bone structure. Certain genes also play a role in predetermining cartilage status, and left untreated and unchecked, this can become extremely debilitating. Since normal joint function requires healthy cartilage and bones, one of the most important substances required for the normal functioning of joints is collagen. As we age, it has been observed that there is a decrease in the production and concentration of collagen in the joints. The lack of this vital structure leads to joint pain and inflammation. Common treatments today include the prolonged use of painkillers and anti-inflammatory drugs, steroids, NSAIDs and COX-2 inhibitors which temporarily relieve pain and cover up the symptoms while the disease moves further. More often, these treatments worsen the condition instead of helping it due to their harmful side effects. A natural supplement containing Collagen II can not only halt the progression of arthritis but can also improve the condition and provide relief to sufferers.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1698) Natural Sweeteners: Which One Should You Take?
Date:
December 09, 2007 03:23 PM
There are many natural sweeteners to choose from if you want to avoid sugar, but don’t want any of the artificial sweeteners over which there are a few questions. You can choose from xylitol, luo han, stevia and others, but before discussing these, let’s have a look at the problems with sugar, artificial sweeteners and the American sugar industry. Sugar as most people know it originates either from sugar cane or sugar beet, though by far the biggest American industry is in the cane. There are many different types of sugar, though that obtainable from cane sugar is sucrose. Sucrose is a disaccharide and carbohydrate, stored by plants as a reserve energy source to be used when needed. Humans cannot directly use sucrose, and it is metabolized in the body to glucose which needs the hormone insulin to help convert it into energy. Insulin is produced in the pancreas, and a lack of it, or the body’s failure to use it properly, is referred to as diabetes. There are two types of diabetes: Type 1: A total lack or deficiency of insulin due to the pancreas producing insufficient quantities of insulin, or even none at all. This is often seen in young people and is generally cause by the immune system attacking the insulin-producing sells in the pancreas. The treatment for type 1 diabetes is to introduce insulin to the blood, normally by means of injections, plenty exercise and the adoption of a high carbohydrate low fat diet. Type 2: This is strongly associated with obesity and weight, and is due either to insufficient insulin production by the pancreas (but not as deficient as for Type 1 diabetes) or an inability of the cells of the body to properly use insulin. Type 2 diabetes does not always require insulin injections, and can be treated by exercise, diet and weight control. However, there are occasions where insulin injections are also required. It tends to affect people older than those with Type 1 diabetes and 90% of cases are of this type. Both types, however, are connected with an excess of glucose in the blood, into which most sugars are converted. A diet low in sucrose will go a long way towards helping people that suffer from either type of diabetes, and control of carbohydrate intake should include a reduction in the intake of sucrose in the form or beet or cane sugar. This accepted, then if you need a sweetener, a saccharide free natural sweetener would appear to be the logical choice. You could opt for a synthetic sweetener, but they also have their problems. There is evidence that saccharin could be a carcinogen, and ‘aspartame’ disease is not a myth. The other artificial sweeteners also have sufficient questions that natural sweeteners would appear to be the obvious choice. But which? That is the question. Let’s have a look at some and check out their pros and cons. The first is Stevia. This is a South American herb that is 400 times sweeter than sucrose and yet is very low in calories and does not affect diabetics. Used throughout most of the world, it has not been approved by the FDA as a food additive due mainly, it would appear, to lobbying by the American sugar corporations. This is understandable, since mass substitution of sugar by stevia in processed foods is entirely possible, but would cost the sugar corporations billions. However, it is available to purchase from health food stores, and does not appear to possess the problems that aspartame does. Unlike that sweetener, it can be used in baking and cooking, and is ideal for diabetics and people suffering from yeast infections such as candida. Such infections are aggravated by sugar in the colon, since yeasts love sugar, but they cannot survive on stevia. The safety of stevia has been proven through hundreds of years of popular use without any problems. However, there are others. Luo Han Guo is a sweet Chinese fruit of which extracts are marketed as a natural sweetener. The plant it comes from is the Momordica grosvenori, a member of the cucumber squash family that grows in the mountainous areas of southern China. The sweeteners it contains are called mogrosides that are terpene glycosides, of which there are five different forms, the main one being termed mogroside-5. The extract is available in the form of a powder consisting of around 80% mogrosides, and possesses around 250% of the sweetness of sucrose. This, too, can be used in cooking; because it is stable to heat and contains about 2% of the calories of ordinary sugar (one half teaspoon is equivalent to 25 teaspoons sugar). You can help 50 medicines go down for the same calories of getting one down using sugar! Not only that but, like stevia, there are no known side effects. It has been used for many centuries in Chinese medicine in the treatment of gastrointestinal conditions and conditions of the respiratory tract. Unlike natural sweeteners, luo han has been found to be useful in helping to manage diabetes since it does not cause insulin levels to rise and are not involved in energy production, so have no effect on your weight. The mogrosides from luo han are also under study as inhibitors of certain tumors, and might be able to inhibit skin tumor growth. Other possible medical advantages include helping to reduce atherosclerosis and heart disease, so would appear to be a useful sweetener to use in your coffee! Finally, xylitol. It was during World War II that Finnish scientists rediscovered xylitol that had been previously used in Germany as a sweetener in the late nineteenth century. The sugar shortage resurrected this substance that can metabolize without the need for insulin. Xylitol is a substance that is found in some fruits and vegetables and also in corn cobs. In fact, it is a product that appears in animal metabolism, and so is perfectly safe. It is known to help support the immune system, and to help reduce the effects of aging. It possesses antibacterial properties due to its 5-carbon ring and has been approved by the FDA. Xylitol can replace sugar in most of its domestic uses, including in baking and as a natural sweetener. It is also used extensively in chewing gum as a sweetener that does not cause dental cavities due the acid caused by bacterial attack on the sugar. However, one use to which xylitol cannot be put, nor any of the other natural sweeteners mentioned here, is in fermentation. Try these for your wine or beer and you will be very disappointed at the low alcohol level of your brew! This is also, however, one of the benefits of xylitol: it cannot feed the yeasts that cause candida or any other yeast infection. Although it is a saccharide, it is the same as the others in this respect. So, which of these natural sweeteners should you take? The choice is yours since each has its own benefits with very few disadvantages and certainly no recorded side effects that we know of. Use stevia for superior sweetening effects, and make up a concentrated solution of it in water for your cooking. Use luo han if you have gastrointestinal problems, and use xylitol if you want fresher breath and to protect your teeth. Use none for brewing or winemaking, and use any of them if you are diabetic. The choice is yours. These sweeteners are available at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1651) Natural Vitamin and Herbal Alternatives For Joint Health
Date:
October 18, 2007 03:58 PM
Joint tissue breaks down and arthritis sets in for a number of reasons, and there are several natural alternatives for joint health that can be use to prevent this and to treat affected joints. Thyroid problems can slow down the production of adrenal hormones that are responsible for the production of cortisone and cosrtisol. These are anti-inflammatories, that when unavailable or in low supply can result in joint inflammation. If you suffer joint pain in the mornings that tends to improve as the day goes on, then it is likely that is the cause since adrenal activity can improve as the day progresses. One of the main reasons for joint tissue breakdown is osteoarthritis whereby the cartilage wears down until it fails to provide the necessary protection against impact between the bones in a joint, or against the friction generated when two bones rub together. Injuries to joints can have the same effect, whereby an injury to a hip or knee can appear to clear up and then later the cartilage wears out sooner than expected. This can take several months or many years, depending on the severity and nature of the injury concerned. Continual wear and tear can also cause joint tissue to break down. Athletes and other sportspersons often suffer twenty years or more after retirement from their sport due to the gradual wearing down of cartilage while they were active. Once they stop, this continues to a lesser extent until the cartilage is eventually worn away sufficiently for it to stop protecting the joint. Problems with the auto-immune system can lead to rheumatoid arthritis and inflammation of the joints. This weakens them and can eventually completely destroy the tissue. In such cases the tissues in the joint tend to swell and become extremely painful. Gout can also damage joints, especially in the big toe. This is caused through a built up of needle sharp uric acid crystals. Another cause is a deficiency in sodium and potassium in the diet that are needed to help maintain calcium in solution. When these metals are in deficiency due, for example, to an adrenal problem or some other reason, calcium can deposit right in the joints, causing undue pain. Calcium and vitamin D deficiencies are commonly associated with arthritis sufferers, and protein deficiencies are also believed to be a contributing factor of rheumatoid arthritis, and it is also true that degenerative arthritis can accompany rheumatoid arthritis. This occurs in almost 40% of cases, and diet and nutrition are now being recognized as a major cause of both types. Deficiencies in folic acid or its natural form of folate, vitamin E, zinc and selenium have all been associated with degeneration of joint tissue, so it makes sense that a supplement of these substances can help to avoid these conditions. Standard medical treatment, however, is for the relief of pain and reduction of inflammation through the prescribing of non-steroidal anti-inflammatory drugs (NSAIDs). Typical NSAIDs are aspirin, ibuprofen and naproxen. Although it relieves pain, paracetamol is not an anti-iflammatory. An alternative to blocking the inflammatory reponse is to help to regenerate the damaged joint tissue. However, reducing the inflammatory response to tissue damage does not address the underlying problem, but masks it. Not only that, but there are side effects associated with the use of NSAIDs. Excessive doses can create serious gastrointestinal problems, such as bleeding, ulcer perforation and even death is possible in severe cases. Anti-inflammatories cause gastric problems in up to 20% of cases The newer Cox-2 inhibitors act on the enzyme that causes the inflammation within the joint, and while these can be very effective, they are still masking the underlying problem. Incidentally, the Cox-2 inhibitors should not be used with NSAIDs, and both increase the possibility of a myocardial infarction or heart attack. Also, if you are taking aspirin to reduce the risk of heart problems, you should be careful not to use other NSAIDs since they can interfere with the effects of the aspirin. More effective in the long run is to treat the conditions with substances that deal with the cause of the problem. Vitamin C, for example, improves the lubrication effect of the synovial fluid in the joints, and vitamin E is a strong antioxidant that can help to repair damaged tissue and improve the circulation within the joints. Joints have very low blood circulation levels, which is a problem when trying to direct drugs to the joint tissues. Vitamin C is also good for improving the integrity of connective tissue. Zinc, manganese and copper are also instrumental in developing strong connective tissue and helping to repair the damage done to the joints. Horsetail is a commonly used herbal remedy that can be taken as a tea, tincture or in capsules. It is the richest natural herbal source of silicon, which is used by the body to form connective tissue and collagen. Damaged connective tissue is rapidly repaired by horsetail, and its strength and elasticity significantly improved. It is commonly used in the treatment of arthritis and osteoporosis. Cat’s Claw is used for its beneficial effect on the immune system, and frequently used successfully to treat osteoarthritis and rheumatoid arthritis. However, this treatment is used more to help reduce the inflammatory effects of the condition than to effect a long lasting cure. Gotu Kola, also called Indian pennywort, is traditionally used for treating arthritis. The fresh leaves are effective in reducing the inflammation and pain, and help to improve the quality of life of arthritis sufferers. In Australia, it is referred to as ‘the arthritis herb’ and two leaves a day are said to be effective. Another popular remedy is MSM (methylsulfonylmethane), although it is claimed to provide pain relief rather than a cure. Amino acids also seem to help, and L-cysteine helps promote collagen and connective tissue. It appears to work best when taken in combination with vitamin E and selenium that are powerful antioxidants. L-arginine has a similar effect in the reconstruction of joint tissue, again helping to repair damaged connective tissues. There are therefore two approaches to treating both rheumatoid and osteoarthritis, one providing pain relief and reducing inflammation, and the other repairing the damage done to the joint tissues. Vitamins, minerals, trace minerals and herbal remedies are used in both, though it is better to use a combination that provides pain relief and also helps to regenerate strong connective tissues in the joints. When using combinations of remedies it is important that possible interactions are understood, and you should always seek the advice of your physician when using non-prescription remedies of any kind.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1597) Memory And Focus
Date:
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Like
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Conclusion
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1533) Safe Solutions for Chronic Pain
Date:
March 30, 2007 12:09 PM
Safe Solutions for Chronic Pain One of the biggest challenged in healthcare today is the problem of pain. There are simply too many people living each and every day with ongoing, unremitting chronic pain. And there are far too many healthcare providers who – for a variety of reasons – are failing to adequately address this serious problem. Recently, 368 doctors who routinely care for patients with chronic pain agreed to take part in a unique study. The doctors were surveyed about the pain medicines hey prescribe, what kind of treatment goals they hope to achieve, and how they felt about their ability to help their patients. They were also presented with four chronic pain vignettes or mock case studies and asked to select the best treatment for each scenario from multiple choice answers. Sadly, many doctors chose the worst treatment options in the case studies. The medications they reported using in their practices did not reflect current pain treatment standards. They tended to set low treatment goals 0 instead of aiming for a least a 75% reduction of pain for their patients, they settled for 10% to 20% reductions. And many of the doctors admitted they lacked confidence in their ability to relieve their patients’ pain and suffering. Adding to the challenge are the almost daily news announcements about dangerous side effects in certain pain medications. Synthetic prescription COX-2 inhibitors, once hailed as the safest of drugs, have been linked to heart attacks, strokes, blood clots, and intestinal bleeding. The over-the counter (OTC) drugs aspirin and ibuprofen kill over 16,000 people each year. And acetaminophen, the most widely used pain reducer in the As a doctor specializing in chronic pain disorders, I know that optimal pain management can be a real challenge. However, I also know: -You do not have to live in chronic pain. -Your chronic pain, no matter what the cause, can be reduced, and usually eliminated. -Chronic pain can be relived both effectively and safely with powerful all-natural compounds. Q. What is chronic pain? A. Sudden, or acute, pain occurs when pain signals immediately fire in your nervous system alerting you to an injury, like a broken ankle, or an illness, such as appendicitis. Once the injury heals or the illness is cured, the transmission of pain signals stop. Ongoing – or chronic pain – is much different. Chronic pain persists. Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial injury, such as sprained back muscles, or an initial illness, such as a serious infection. There might be an ongoing cause of pain, such as arthritis, cancer, or fibromyalgia. Chronic pain also occurs without any past injury or evidence of body damage. The most common kinds of chronic pain are headache, low back pain, cancer pain, arthritis pain, and neurogenic pain (pain resulting from damage to nerves or to the nervous system itself). While chronic pain differs in its origin and where it occurs, it is generally your body’s way of saying that something urgently needs attention, and will not o away unless its underlying causes are addressed. These causes can usually be determined if you remember the acronym “SHIN”. This stands for Sleep, Hormonal deficiencies, Infections/Inflammation/Impingement, and Nutritional deficiencies. When these are treated, pain often resolves. Q. Why is it so hard to effectively reduce chronic pain? A. Unfortunately, many physicians’ entire education in pain management consists of “giving nonsteroidal anti-inflammatory drugs or NSAIDs (pronounced en-sayds), COX-2 inhibitors, or acetaminophen and considering narcotics if the patient has cancer. Some NSAIDs, like aspirin and ibuprofen, are available over-the-counter, while others, like the synthetic COX-2 inhibitors are only available with a doctor’s prescription. These mediations are usually inadequate and often toxic when used for chronic pain. And they do not address the problem(s) that the pain is trying to alert you to. Q. What exactly are COX-2 inhibitors? A. COX-2 inhibitors do pretty much what their name implies – they inhibit a natural enzyme in our body called the clclooxygenase-2, or COX-2, enzyme. There are two COX enzymes – COX-1 and COX-2 and both complete several actions in our bodies. One very important action that both COX-1 and COX-2 enzymes share is the speeding up of our body’s production of prostaglandins. These hormone-like substances are made by the cells of the body and have several important functions. Some of the most powerful prostaglandins cause inflammation, pain, and fever when we are sick or injured. Prostaglandins also protect the lining of the stomach from the damaging effects of acid. Other prostaglandins make sure our platelets (important blood cells) make blood clots when needed. Still others help our kidneys get rid of unwanted salt and water. And researchers have just recently recognized the importance of still another prostaglandin that protects our heart and blood vessels. The NSAIDs reduce pain by reducing prostaglandin production by blocking or inhibiting the COX enzymes. In theory – less prostaglandins, less pain and welling seems reasonable. But if you really stop and think about it, it’s pretty easy to understand why this method of pain relief might result in significant consequences. Pain and inflammation are often needed for healing. And just as needed is the protection of our stomach lining, blood clotting ability, assisting kidney function, and keeping our blood vessels healthy. And scientists are beginning to understand if you interfere with one natural response, you may be disrupting the body’s ability to prevent extremes and imbalances. That’s why using aspirin and ibuprofen can result in stomach ulcers, kidney problems, and internal bleeding. And that’s why using synthetic COX-2 inhibitors can result in high blood pressure, blood clots, heart attacks, and strokes. Q. Why are we just now learning about the dangers of COX-2 inhibitors and other NSAIDs? A. That’s a good question! Many people over the age of 65 have chronic pain conditions and are frequent users of OTC and prescription NSAIDs. This age group also experiences heart disease and Alzheimer’s disease in greater numbers. So, if a 70 year old woman who’s been using Celebrex for the past two years for arthritis in her knees suddenly has a heart attack one morning, it would not be entirely unexpected. For the past five or six years, researchers have been studying the possibility that NSAIDs may prevent certain cancers, Alzheimer’s disease, and other health problems. The ongoing, close scrutiny of large group of people taking these medications by scientists who were conducting these studies has resulted in the discovery of these dangers. Q. What kind of natural compounds relieve chronic pain? A. There are many – glucosamine, Omega-3 fatty acids, the B vitamins – the list goes on and on. Instead of disrupting normal bodily responses, these natural compounds work in harmony with our body to eliminate chronic pain. Three very powerful and very effective all natural plant compound pain and inflammation relievers are Sweet Cherry, Boswellia serrata, and White Willow Bark. For many years there have been anecdotal or personal reports that claimed eating Sweet Cherries, specifically Prunus avium, wipes out back pain, arthritis, and gout. While anecdotal reports generally don’t account for much in the world of science, he sheer numbers of testimonials proclaiming the Sweet Cherry’s amazing ability to reduce pain made researchers sit up and take notice. When Sweet Cherries were examined in the lab, it was easy for scientists to understand how this natural fruit is able to relieve pain. It seems Sweet Cherry’s bright red color is the key. Like many deeply colored fruits, Sweet Cherries are full of flavonoids called anthocyanins and proanthocyanidins. These powerful plant compounds scavenge and destroy altered oxygen compounds called free radicals. Many degenerative, chronic diseases have been associated with the tissue damage caused by free radicals, including arthritis, heart disease, peripheral artery disease, and cancer. Cherry fruit extract is a natural anti-inflammatory compound, making it an excellent treatment for arthritis, fibromyalgia, and other chronic pain and inflammation diseases. A pain relieving plant compound that comes from the bark of a tree, Boswellia serrata has been used by Indian healers for hundreds of years to reduce painful inflammation. When 20th century researchers looked at extracts of Boswellia Gum Resin in the laboratory they discovered the presence of powerful plant compounds, called boswellic acids. Researchers found Boswellic Acids reduce inflammation in several ways. They open constricted blood vessels, improving blood flow to joints. They balance levels of leukotrienes – specific chemicals in the body that cause inflammation. And Boswellic Acids block two inflammatory chemicals that increase in asthma and inflammation of the colon. In addition to being helpful in treating these 2 illnesses, Boswellia has also been clinically studied and found to be quite effective in osteoarthritis and rheumatoid arthritis without any evidence of ulcers or stomach irritation. Another bark extract, White Willow Bark is one of the oldest and most effective pain relievers. For over 2,000 years extracts from the bark of the White Willow tree have been used to ease aches and pains and reduce fevers. It is the original source of aspirin, but when used as the entire plant medicine, White Willow Bark is much safer than aspirin and quite effective. White Willow Bark’s active ingredient is salicin and the combination of other compounds in the bark significantly enhances its pain killing power. In two large clinical trials of patients with chronic low back pain. White Willow Bark was found to be not only safer and much more effective than standard prescription therapies, it was also 40 percent more cost effective. Salicylic acid from White Willow Bark lowers the body’s levels of prostaglandins, easing both acute and chronic pain. White Willow Bark reduces the pain and swelling of arthritis, headache, back and neck pain, muscle aches, and menstrual cramps. But, unlike aspirin, it doesn’t cause stomach bleeding or other known adverse effects. Q. Do Sweet Cherry, Boswellic Acids, and White A. They do indeed. Because they reduce both pain and inflammation by a broad combination of actions, these natural extracts have been proven to be excellent against arthritis, back pain, and pain from inflammatory intestinal diseases (Crohn’s disease and ulcerative colitis), and would be expected to be helpful in most kinds of pain. Sweet Cherry, Boswellic Acids, and White Willow Bark relieve inflammation without causing stomach irritation, stomach ulcers, high blood pressure, blood clots, heart attacks, or strokes. That’s because these natural pain killers don’t disrupt the balance of enzymes or interfere with the body’s ability to prevent extremes and imbalances. However, as with any pain therapy, Sweet Cherry, Boswellic Acids, and White Willow Bark work best when they are used as part of a comprehensive treatment plan to relieve the most common underlying causes of chronic pain or SHIN. In addition, although these excellent natural remedies can often offer quick pain relief, natural remedies for severe chronic pains work best when they are given at maximum allowed doses and given 6 weeks to show their full effectiveness in combination with treating the pain’s underlying causes. The best chronic pain relief results when doctors and patients work together to meet the goals of treatment. Some important last notes: Many causes of chronic pain are serious and life threatening. Everyone who is living with chronic pain must consult their doctor or other healthcare practitioner to determine the reason for their ongoing discomfort. In other words – make sure you know why you are having chronic pain and what’s causing the pain you want to relieve. There are some types of chronic pain that only respond to opioids, or narcotic pain relievers. Morphine sulfate is an excellent pain medication and is used to relieve surgical pain, the pain of heart attacks, and pain from serious injuries. Morphine is also the very best drug for chronic cancer pain and non-malignant chronic pain. While many people fear opioids, these powerful pain killers can dramatically improve quality of life. If you are suffering with chronic cancer pain and you are hesitant to use morphine or another opioid, I urge you to discuss your concerns with your doctor other healthcare provider. No one with cancer should live with untreated or under-treated pain. Conclusion Even chronic pain can often be eliminated when SHIN is in combination with powerfully effective natural pain relievers. But, because some people may need to take pain relievers the rest of their lives, the medications they use must be safe as well as effective. The very safest come from natural plant compounds that have been studied for their ability to relieve chronic pain. You can become pain free and Sweet Cherries, Boswellic Acids, and White Willow Bark can help.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1503) Glucosamine Sulfate and Chondroitin Sulfate
Date:
March 28, 2007 11:10 AM
Glucosamine Sulfate and Chondroitin Sulfate Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years. While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of glucosamine sulfate (GS), which actually addresses the underlying joint destruction. Q. What is osteoarthritis? A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work. A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed synovial joints, and have the greatest range of movement and mobility of human joints. To allow such mobility, synovial joints have a unique structure. The bones that form synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called synovial membrane. The membrane secretes synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement. The cartilage of synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; synovial joints move easily. Secondly, synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement. Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones. Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain. People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days. Q. What causes osteoarthritis? A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse. Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees. Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage. Q. Can osteoarthritis be prevented? A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures. Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis. Q. What treatments are available for osteoarthritis? A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis. These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur. Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur. Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself. That is why many believe glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve synovial joint health. And they do this without potentially life-threatening side effects. Q. How do GS and CS work? A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints. There is even more good news. When glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness. Glucosamine occurs naturally in the body and is found in synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints. In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study glucosamine, they discovered GS can reduce synovial joint inflammation. This explains why people felt better after taking it. Q. What has additional study of GS and CS revealed? A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better. GS is the form of glucosamine used in research. It’s the sulfate salt of glucosamine and breaks down into glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis. CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS. Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together? A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies. Q. Why is it important to take low-molecular weight CS? A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment. However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS. This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the synovial fluid of joints where it’s needed. Q. Are there other supplements that can help osteoarthritis? A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis. Folic acid and vitamin B can reduce the number of tender joints and increase joint mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis. Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals. Q. Is there anything else I can do for joint pain and stiffness? A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home. Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints. The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis. One important last thought When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis. Conclusion Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health. Buy Glucosamine and Chondroitin Sulfate at Vitanet ®, LLC
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1500) Benefits - Supports joint function and tissue health*
Date:
December 11, 2006 03:46 PM
To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage. Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3 Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3 Promotes optimal joint comfort, function and flexibility* Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4 Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7 Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8 Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11 Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results. Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption* Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14 Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability. Sustained Release – For lasting joint comfort and convenient dosing To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day. Safety Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.
Scientific References 2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149. 4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7. 5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146. 6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002. 7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5. 8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers. 9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46. 10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7. 11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308. 12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34. 13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232. 14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J. 15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1438) Olive Leaf Extract
Date:
January 02, 2006 10:17 AM
In today’s stressful world, immune system health is more important than ever. History has proven that no matter what we do to combat viruses, bacteria and parasites, they have the remarkable capability to mutate for survival, often returning in a more virulent form than before. New strains of the flu and other microbial invaders are being discovered at an alarming rate, and modern medicine is constantly on the defensive. At the time this was written, the Centers for Disease Control (CDC) in Atlanta is predicting a “bad flu season” because a “killer drift variant” strain of flu had been discovered, called type A Fujian. This new strain has already caused deaths abroad, and vaccinations are strongly recommended, especially for the very young and the elderly. However, mutating microbes are only part of the problem confronting our immune systems. Factors such as environmental pollution and over-processing of foods are believed by many researchers to play a major role in many health conditions. Which means, more than ever before, you need to make sure your immune system is functioning at peak efficiency. Fortunately, there are a number of natural products available that can assist you in reaching this goal. One of the most effective discovered to date is Olive Leaf Extract (OLE). Natural olive leaf extract is derived from the olive tree (Olea europaea), which happens to have a very long and interesting history. One of the most revered botanicals, the olive tree is mentioned numerous times in the Bible. One of the earliest and most powerful mentions is the delivery of the olive branch to Noah by a dove, a sign that the floodwaters were receding and life was returning. The olive tree was, and still is, a life-giver. It’s fruit is used for food, and the oil is used for cooking and as a source of light to ward off the darkness. Ancient cultures soon discovered that the various components of the olive tree provided a myriad of health benefits as well, benefits confirmed by modern science. Extract of olive leaves is one of the best, if not THE best, natural antimicrobials and antioxidants ever discovered.* Oddly enough it might have been well recognized in this role much sooner since it was reported in the mid-1850’s that a bitter tea brewed from olive leaves might be a potential cure for malaria. However, not all great discoveries are immediately recognized as valuable, and physicians of that era didn’t give much credence to the reports. It wasn’t until decades later that a simple analysis conducted on olive leaves led to the discovery of an active component, the phenolic compound oleuropein, which has since been associated with many health benefits. More recently, numerous studies have been conducted on olive leaves and the active components found in the leaves, with a preponderance of positive results. A 1999 study conducted at the University of Rome assessed the antimicrobial activity of oleuropein and hydroxytyrosol, two of the most active components in olive leaf extract. They were pitted against many different bacterial strains, including salmonella and staphylococcus, in vitro. The study concluded, “Olea europaea can be considered a potential source of promising antimicrobial agents” for the support of intestinal and respiratory health.* 4 A 2002 study conducted at the University of South Australia compared the effectiveness of some of the typical components of the Mediterranean diet, including oleuropein and hydroxytyrosol, as reactive oxygen species inhibitors and free radical scavengers. Researchers also examined their capability in protecting against low-density lipoprotein oxidation in vitro. Results clearly indicated that these components are potent inhibitors of free radical generation, as well as effective free radical scavengers.* 5 NOW® Foods carries a number of olive leaf extract products, including our Olive Leaf Extract 500mg, standardized to contain 6% oleuropein, our Extra Strength product with 18% oleuropein and 100mg of Echinacea Extract, and Olive Leaf Glycerite liquid, which contains 18% oleuropein. Why would you want a standardized Olive Leaf Extract product over a whole herb Olive Leaf product? We’re glad you asked! Standardization allows for consistently effective herbal products because the active ingredient, or marker compound, is accurately identified and measured, ensuring that the product delivers a certain minimum level of the active component or components. In simpler terms, standardized herbal products allow the consumer to obtain the benefits of an herb without having to consume massive quantities because there is a much greater concentration of active components, which also improves the effectiveness of the herbal product. Purchasing standardized Olive Leaf with a guaranteed concentration of oleuropein is a smart choice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1147) Super Cortisol Support Fact Sheet
Date:
December 08, 2005 07:04 PM
Super Cortisol Support Fact SheetNeil E. Levin, CCN, DANLA 10/1/05LIKELY USERS: People under a lot of stress; People who suffer from stress-related eating; People who may have metabolic syndrome (Syndrome X); KEY INGREDIENTS: Relora®13, Rhodiola14-20, Reishi 21-24, Green Tea Extract25-32, Holy Basil, Ashwaganda, Banaba, Pantothenic Acid, Calcium Ascorbate, Magnesium, Lecithin, Chromium MAIN PRODUCT FEATURES: NOW® Super Cortisol Support is an herbal and nutritional formula designed to support healthy adrenal function and maintain healthy cortisol levels. The adrenal glands help the body respond and adjust to stress generated from both internal and external forces. Under chronic stress, cortisol can be overproduced, resulting in weight gain and difficulty in managing healthy blood sugar levels. Super Cortisol Support combines adaptogenic herbs with Chromium, Corosolic Acid and Relora® to help the body manage the negative effects of stress such as abdominal obesity, overeating and low energy levels. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy energy levels throughout the day1-6. Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy immunity1-9. Along with Chromium, and Corosolic Acid, these herbs also help to support healthy serum glucose levels1-12. Relora® has been included in this formula to alleviate symptoms associated with stress such as irritability and nervous tension13. This formula is recommended by Hyla Cass, MD. This is the first Cortisol formula to use Relora®, a natural proprietary blend of a patented (U.S. Patent No. US 6,582,735) extract of Magnolia officinalis and a patent-pending extract from Phellodendron amurense. Relora® was developed as an ingredient for dietary supplements and functional foods that could be used in stress management and for stress-related appetite control. This patented blend of plant extracts is the result of screening more than fifty plant fractions from traditional plant medicines used around the world. Relora® has excellent stress management properties without causing sedation. Overweight adults may have excessive abdominal fat due to stress-related overeating. Relora® appears to maintain healthy hormone levels in stressed individuals and act as an aid in controlling weight and stress-related eating.33 SERVING SIZE & HOW TO TAKE IT: One capsule, two to three times a day. COMPLEMENTARY PRODUCTS: Holy Basil, Green Tea, L-Theanine, Licorice Root, Vitamin C, Eleuthero Root, Pantothenic acid CAUTIONS: None. SPECIFIC: Some of these ingredients may support the body’s blood sugar controls, so people taking blood sugar medications should inform their physician before using Super Cortisol Support, and their glucose should be monitored when taking this formula so their medication strength can be modulated appropriately to avoid an overdose of medication. No side effects have been noted for this dosage of Relora®. GENERAL: Pregnant and lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
1. Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV (2000) Phytomedicine 7(2):85-89.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1003) Sytrinol can lower Cholesterol by 27% - 34%
Date:
September 20, 2005 09:56 AM
Sytrinol – MultiPronged Heart Health According to the American Heart Association, more than 60 million Americans suffer from on of more forms of cardiovascular imbalances. When we add in those individuals with blood cholesterol concerns, we see over 100 million Americans who may be in need of specific diet and lifestyle recommendations for achieving and maintaining heart health. Aside from the generalized recommendations that we typically hear for heart health (lose weight, exercise more, and eat less fat and more fruits and vegetables) There are a number of potentially beneficial dietary supplements that may help to maintain cholesterol levels in the normal range. Among supplements there is a wide range of safety and efficacy between products—but a newer product called Sytrinol stands out for its clinical effectiveness. Sytrinol is a patented blend of polymethoxylated flavones (from citrus) and tocotrienols (from palm fruit). One of the factors that sets Sytrinol apart from existing natural products for heart health is its multipronged approach to controlling multiple factors related to overall heart health—including control of cholesterol, cellular irritation, oxidation, triglycerides, and others. Cholesterol Conundrum While it is unarguable that cholesterol is an important contributor to overall heart health, it couldn’t be further from the truth that cholesterol is the “only” or even the most important factor when it comes to protecting your heart. Did you know that approximately HALF of all serious heart challenges each year are experienced by people with NORMAL cholesterol levels? If Cholesterol is not to blame, then what is? In addition to total cholesterol levels (the “number” that you may know as 200 to 240 of other values in “mg/dl” units), we know how that LDL and HDL matter a lot (Low-density lipoprotein—the “bad” cholesterol, and High-density lipoprotein—the “good” cholesterol). We also know that some forms of the bad and LDL can be “Badder” than others—specifically those with lots of structural protein called “apolipoprotein B” (which tends to encourage LDL cholesterol to become embedded in your blood vessel linings—bad!). In addition to our total cholesterol, LDL, HDL, and the various apoproteins, we also need to know our triglyceride levels, our levels of cellular irritation, what our free radical load looks like, and what our antioxidant defenses are. Sytrinol addresses each of these important aspects of heart and health simultaneously. The Sytrinol Solution Polymethoxylated Flavones (PMFs) in Sytrinol are just what they sound like – flavonoid compounds with extra methoxy groups compared to “regular flavones. Like all flavonoids, the PMFs deliver potent antioxidant activity, but the PMF version is about three times more potent in its ability to address cholesterol levels (20% - 30% reduction in clinical Studies). The two primary PMFs are nobiletin and tangeretin. In addition to the PMFs, Sytrinol contains palm tocotrienols—one of the most potent antioxidant nutrients known. An interesting effect of tocotrienols is a reduction in cholesterol synthesis in the liver—by a mechanism similar to (but safer than) the commonly utilized mechanism of inhibition of the HMG-CoA Reductase Enzyme. Sytrinol is known to work via several unique mechanisms to reduce triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL). First, by reducing DGAT activity (Diacylglycerol acetyl transferase) and increasing liver PPAR (Peroxisome porliferator-activated receptor)—Sytrinol can reduce overall synthesis of TG (DGAT inhibition). The overall effect is to reduce TG levels in the blood by two complementary mechanisms. In terms of LDL effects, Sytrinol also reduces both Apolipoprotein B levels (ApoB—needed for the synthesis of LDL particles) and MTTP levels (microsomal triglyceride transfer protein-needed to transfer fat into the new LDL particles). By reducing levels of both these tructural LDL components, Sytrinol reduces overall LDL levels, and thus total cholesterol levels, in the blood. The clinical results behind Sytrinol are impressive—showing a reduction in levels of total, LDL, and triglycerides by 27% - 34% within 4 weeks. In one of these studies, ApoB levels were reduced (suggesting reduced LDL) and ApoA1 levels were increased (suggesting increased HDL)—as would be expected based on the biochemistry of PMFs and tocotrienols. Sytrinol is also wonderfully safe—and at the effective dose of 300mg daily, users will benefit from its multipronged effects. One aspect of Sytrinol safety that I especially like is the finding that, unlike some flavonoids like naringin from grapefruit, there are no known risks of drug interactions with the form of citrus derived PMFs found in Sytrinol (certain grapefruit flavonoids can interfere with liver enzymes needed to metabolize many prescription drugs). Summary Not since Red Yeast Rice was removed from the market by the FDA, have we had a truly effective, multimechanism solution for cholesterol control (and nearly total heart health). There are certainly other options for addressing heart health and cholesterol levels, but among the available choices, such as policosanol, guggulipid, niacin, and plant sterols, we’re looking at about half the cholesterol-lowering ability (10% - 15% in most cases) compared to Sytrinol. If youre in the “borderline” zone of cholesterol levels (about 240mg/dl and below), you should absolutely consider Sytrinol to keep your cholesterol levels under control. References Kurowska EM, manthey Ja. Hypolipidemic effects of absorption of citrus polymethoxylated flavones in hamsters with diet-included hypercholesterolemia. J Argic food chem.. 2004 may 19;52(10):2879-86. Kurowska EM, manthey Ja, Casaschi A, Theriault AG. Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, Tangeretin. Lipids 2004 feb;39(2):143-51. Manthey JA, Grohmann K, Montanari A, Ash K, Manthey CL, Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human moncytes. J Nat Prod. 1999 mar;62(3)441-4. Mora A, Paya M, rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem Parmacol. 1990 Aug 15;40(4):797-7. Takanaga H, Ohnishi A, Yamada S, Matsuo H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol exp. Ther. 2000 Apr;293(1):230-6. By: Shawn M. Talbott, PH.D. Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=791) SLEEP DISORDERS AND ST.JOHN'S WORT
Date:
July 15, 2005 09:28 AM
SLEEP DISORDERS Among the many ailments that often accompany middle and old age are various sleep disorders: insomnia, intermittent waking, sleep duration, and an overall poor sleep quality. The medical world has produced numerous synthetic drugs to deal with these disorders; however, most aren’t completely effective and produce undesirable side effects as well. Recent research suggests that St. John’s wort may be able to improve one’s sleep, especially that of older persons. A 1994 double-blind, placebo-controlled study published in the Journal of Geriatric Psychiatry and Neurology showed that Hypericum extracts gave the benefit of increased deep sleep during the total sleeping period of the patients. It explains, A hypostatic influence of the REM sleep phases, which is typical for tricyclic antidepressants and MAO inhibitors, could not be shown for this phytopharmacon [Hypericum]. Instead, LI 160 [Hypericum] induced an increase of deep sleep during the total sleeping period. This could be shown consistently in the visual analysis of the sleeping phases 3 and 4, as well as in the automatic analysis of slow-wave EEG activities. The study also makes an interesting connection between sleep and depression; that being many standard antidepressants and MAO inhibitors used to treat people who suffer from depression cause a decrease in deep sleep. As discussed earlier, St. John’s wort has shown great promise in treating depressed persons. So, besides helping people with sleep disorders, when used as an antidepressant, it gives antidepressant properties without the side effect of decreased deep sleep.21 This is certainly another valuable quality St. John’s wort has shown to possess.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=631) THERAPEUTIC APPLICATIONS OF ST. JOHN’S WORT DEPRESSION—AN OVERVIEW
Date:
July 15, 2005 09:12 AM
THERAPEUTIC APPLICATIONS OF ST. JOHN’S WORT DEPRESSION—AN OVERVIEW Depression is a disorder that affects millions of people, both Americans and worldwide. It takes many forms, but is usually marked by sadness, inactivity and heightened selfdepreciation. Hopelessness and pessimism are often common symptoms, as are lowered self-esteem, reduced energy and vitality, and loss of the overall capability to enjoy one’s existence. Depression is probably the most common psychiatric complaint offered to doctors, and has been described by physicians from at least the time of Hippocrates, who called it “melancholia.” The course the disorder runs varies widely from person to person. Depression may be short-term, or may occur repeatedly at short intervals. It may be somewhat permanent, mild or sever, acute or chronic. And who does depression most affect? Rates of incidence are higher among women than men (for varying reasons, some not totally understood). And men are more at risk of suffering from depression as they age, while a woman’s peak age for experi-encing depression is usually between the ages of 35-45. Depression is caused by many things—it could come about because of childhood traumas, or because of stressful life events—but more and more, doctors and scientists are pointing to biochemical processes as a main culprit in the onset of depression. Defective regulation of the release of one or more naturally occurring monoamines in the brain—particularly norepinephrine—leads to reduced quantities or reduced activity of these chemicals in the brain, bringing on the depressed mood for most sufferers. Accompanying the increase in depression cases and the emerging knowledge of its causes has been the rise of drug and other therapies in treating the disorder. The two most important are drug therapy and psychotherapy. Psychotherapy aims to resolve any underlying psychic conflicts that may be causing the depressed state, while giving emotional support to the patient. This usually involves seeing a psychiatrist and/or psychologist at regular intervals. This also may be accompanied by participation in support groups. Antidepressant drugs, on the other hand, directly affect the chemistry of the brain and its chemicals, such as the monoamines that are thought to have the most effect on depressed emotional states and moods. The tricyclic antidepressant drugs are thought to work by inhibiting the body’s physiological inactivation of the monoamine transmitters. This results in the buildup or accumulation of these neurotransmitters in the brain and allows them to remain in contact with nerve cell receptors longer, thus aiding in elevating the mood of the patient. There are other drugs, called oxidase inhibitors, which interfere with the activity of monoamine oxidase, an enzyme known to be involved in the breakdown of norepinephrine and serotonin.5 While drug therapy is something more favorable than continuing suffering from depression, for many persons who take these medications it brings on very undesirable side effects. Uncomfortable physical side effects are among the biggest complaints. Many drug users suffer from sensations of nausea, bloating, indigestion, abdominal cramping and diarrhea, and other gastrointestinal discomforts. Dizziness is often a common complaint, and there are many others. For decades, St. John’s wort has been utilized as a mood elevator, antidepressant and overall mental stimulant. As mentioned before, since times as far back as the Crusades do we have record of St. John’s wort being used in this and other capacities. Wounds were treated with the herb’s extracted oil, the insane were given the herb for its effect on both the nervous system and brain, and it was even used to cast out evil spirits (which often is linked to hallucinations and other mental instability). More recent uses in “folk” or nonstandard medicine point to St. John’s wort’s effective use not only as an antidepressant and nervous system tonic, but also for neuralgia, wounds, kidney problems, its anti-inflammatory and antibacterial properties, and of very recent interest, its use as an AIDS virus inhibitor. Michael Murray, in his book Natural Alternatives to Over-the-Counter Drugs, points to St. John’s wort’s uses for the previously listed uses, and the results of several recent clinical studies. Rebecca Flynn and Mark Roest also outline very well the benefits of the herb as shown in medical and other tests.6 The information coming from both the folk medicine and the clinical medicine worlds indicates that St. John’s wort possesses effective and safe healing properties for several disorders and ailments, and potentially many more.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=625) Quercetin and Bromelain - for better health.
Date:
July 04, 2005 10:28 AM
Benefits Down-regulates the Body’s Response to Environmental Challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10 Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges. Maintains Tissue Comfort by Regulating Enzymes* Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures. Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13 Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16 Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of free-radicals such as hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19 Helps Maintain Normal Blood Viscosity* Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.* Bromelain May Enhance Quercetin Absorption In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.
Scientific References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=546) UROVEX: BUTTERBUR EXTRACT Supports healthy urinary urge and frequency Promotes healthy ...
Date:
June 29, 2005 02:13 PM
UROVEX: BUTTERBUR EXTRACT Supports healthy urinary urge and frequency Promotes healthy bladder control Fear—the fear of job loss, embarrassment in social settings, sexual frustrations and psychological stress. That’s what life is like for the nearly 30 million people in the United States who have concerns with bladder control. A burden at any age, bladder issues are highly prevalent in both genders but more common in women. Urinary urge and frequency occurs when the smooth muscle of the bladder contracts without warning. SOURCE NATURALS UROVEX BUTTERBUR is a patented standardized extract that supports healthy urinary urge and frequency. Further, it has been shown to help minimize the sudden urge to urinate, according to a human clinical trial. It has also been shown to support smooth muscle relaxation in animal studies. In vitro studies show that UROVEX BUTTERBUR may reduce bladder cell irritation by inhibiting leukotriene synthesis. What Goes On If you experience this circumstance, you probably have two of the following indicators: frequency of urination (usually more than 8 times in 24 hours), urgency (an immediate and strong urge to urinate) and leaking or involuntary loss of urine. Although the changes in urinary anatomy—the result of normal aging—do not cause urinary trouble, they do create a situation that allows this to occur more easily. Aging results in a reduced size of the bladder, producing a decreased bladder volume and a need for more frequent bladder emptying. Urination involves physiological processes within the urinary tract and the brain. Our brain normally suppresses the urge to urinate until we initiate urination. Neurons in the brain and in smooth muscle of the bladder involuntarily govern the detrusor (layered, smooth muscle that surrounds the bladder) muscle. This muscle contracts and relaxes based on the volume of urine in the bladder and the initiation of urination. The desire to urinate usually starts when the bladder has reached about half its physiologic capacity. This desire is suppressed by the cerebral cortex until a suitable time and place has been chosen. Butterbur relaxes the detrusor muscle, which reduces pressure on the bladder and thus relieves the urge to urinate. Each capsule contains 50 mg of standardized butterbur, yielding 7.5 mg of the active ingredients petasin and isopetasin. Our extract has been specially processed to remove undesirable pyrrolizidine alkaloids found in some brands. Newest Research UROVEX BUTTERBUR EXTRACT has been shown in research to improve the sudden urge to urinate. In one study, 24 women were given butterbur for 8 weeks. After three weeks, 17 women reported a significant reduction of the frequency of urination. Before they began taking butterbur, urination intervals were 30 to 90 minutes, while three weeks later the intervals of 17 of the women were between 90 and 150 minutes. Butterbur is a perennial shrub native to Europe, northern Africa and southwestern Asia that has been used medicinally for centuries to maintain a healthful, active lifestyle. The use of preparations from butterbur has included promoting proper smooth muscle tone, including relief for painful menstrual cramps and other traditional uses. An All-Natural Solution Source Naturals is pleased to partner with your natural food product retailer to deliver this botanical treasure that is so effective in solving this often untreated problem. Look for Source Naturals UROVEX BUTTERBUR. It is the only patented butterbur product for bladder control and other traditional uses and is available in 12, 30 and 60 capsule bottles.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=531) GREEN COFFEE EXTRACT - Powerful Natural Antioxidant
Date:
June 29, 2005 11:06 AM
According to the National Coffee Association’s 2001 National Coffee Drinking Trends survey, 52 percent, or 107 million, U.S. adults drink coffee each day. Although you may already enjoy coffee as your favorite way to begin the morning, new studies are revealing its impressive health benefits. GREEN COFFEE EXTRACT (GCA®) is a newly discovered powerful antioxidant that helps protect against oxidative stress caused by free radicals - a major cause of accelerated aging. Source Naturals GREEN COFFEE EXTRACT (GCA®) is a patent-pending, all-natural green coffee bean extract derived from raw, unroasted coffee beans. It is high in chlorogenic and caffeic acids, two primary compounds responsible for its antioxidant activity. GREEN COFFEE EXTRACT is naturally low in caffeine and contains at least 65 percent total polyphenol antioxidants. The Coffee Story The history of coffee dates back more than a thousand years. Originally, coffee beans were used as food. East African tribes would grind the coffee berries together, mixing the results into a paste with animal fat. Later, around 1000 AD, Ethiopians made a type of wine from coffee berries, fermenting the dried beans in water. Coffee also grew naturally on the Arabian Peninsula where it was first developed into a hot drink. Despite decades of research on coffee and caffeine, there are many misconceptions about the potential health risks associated with coffee, while many of the beneficial aspects have gone unnoticed. Polyphenols: Powerful Antioxidants Phenolic compounds, or polyphenols, are a widespread family of compounds found in all plants including grapes, coffee and tea. They possess outstanding antioxidant and free radical scavenging properties, which may help defend cells and protect the body against the effects of aging. The high antioxidant activity observed in research on coffee is believed to be mostly due to the phenolic acids. GREEN COFFEE EXTRACT contains a number of polyphenols called hydroxycinnamic acids, with the two most prominent being chlorogenic and caffeic acids. Caffeic acid is the most abundant phenolic compound in coffee. In vitro and in vivo studies show that these acids protect against low-density lipoprotein (LDL) oxidation and lipid peroxidation. Glucose Metabolism There is accumulating evidence that certain dietary polyphenols, such as chlorogenic acid, may have biological effects in the small intestine that alter patterns of glucose uptake. Chlorogenic acid has been shown to inhibit glucose 6 phosphate (Glc-6-Pase) activity. Glc-6-Pase is an enzyme that has a key role in regulating glucose metabolism. An in vivo study on rats demonstrated that chlorogenic acid improved glucose tolerance. Natural Wellness Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN COFFEE EXTRACT.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=525) Move it and Lose it! Burn off body fat!
Date:
June 14, 2005 12:04 PM
Move it and Lose it! Burn off body fat! by Mimi Facher Energy Times, June 1, 1997 So you're feeling a little blah, a little overweight, and you're looking to drop a few of those winter pounds gained during the colder months. Maybe you've dabbled with diets and jogged around the neighborhood a few times but you're still packing unsightly bulges. If so, you may be considering the idea of turning to supplements to help you drop those pounds. Well, two types of diet supplements now generally available, combined with a diet and exercise program, may be able to help you trim those stubborn pounds. The first type of supplement, called metabolic optimizers, which include ephedra, caffeine and salicin (derived from willow bark), boost your metabolic rate, causing your body to burn calories faster. The second class, lipotropic substances, aid the body in fat mobilization, causing greater utilization of stored fat. These products include chromium, carnitine and hydroxycitric acid (HCA). Both classes of supplements have been around in various forms for quite a while but are now enjoying greater popularity among dieters. Trying to cope with a weight problem is a dilemma expanding throughout modern society. According to a 1995 Harris poll, nearly 75% of Americans are overweight. Although it's well known that the way to lose weight is to expend more calories than you take in, supplements may be able to help you burn off extra calories. Thermogenesis and You Metabolic optimizers are supposed to aid weight loss through a process called thermogenesis. Thermogenesis is a natural process in which fat is burned to produce body heat. Fat that isn't burned is stored on the hips, thighs, stomach, etc. Thermogenic agents are designed to counteract your body's fat storage mechanisms by causing your body to maintain a higher metabolic rate-turning your internal thermostat up to burn fat faster. The thermogenic process can be jump-started by a number of factors including cold, exercise, certain dietary nutrients and metabolic optimizers. Ephedra The ephedra herb, also known as ma huang is one of nature's earliest medicines, known for over 5000 years to the Chinese, who used it to relieve allergies, coughing, wheezing and cold and flu symptoms. In the US, ephedra has been available since the 1800s. The ingredients in ephedra include the alkaloids ephedrine, pseudoephedrine and norephedrine. Concentrated forms of these substances are used in today's over-the-counter cold, allergy and asthma relief formulas. Ma huang's effectiveness as a weight loss aid is tied to its appetite suppressant and stimulant properties. By speeding up action of the thyroid gland, the ephedrine found in the herb acts a thermogenic agent, boosting the rate at which the body metabolizes fat and promoting weight loss. According to Mark Blumenthal, Executive Director of the American Botanical Council, "When used as part of a total package that includes diet modification and exercise, ma huang can be highly effective in the short run because it increases the speed of the body's metabolism and suppresses appetite." Because of their strong stimulant effect, ephedra and its derivatives have engendered some controversy. However, in its long history, billions of doses of ephedra have been consumed without problem. But ephedra supplements should only be used as directed on product labels. People with cardiovascular problems, diabetes, thyroid or prostate dysfunction, high blood pressure and those taking MAO inhibitors, pregnant or nursing should avoid this herb. Salicin Burns Fat Salicin, a substance derived from willow bark-which is also the original source for aspirin, a related compound-can boost the burning of fat when combined with ephedra. An animal study in the American Journal of Clinical Nutrition found that while ephedra boosted calorie burning by almost 10%, when ephedra was combined with aspirin, extra calorie burning just about doubled. Another study in the Internatioanl Journal of Obesity showed that when overweight women took aspirin and ephedrine during a meal, their bodies burned off more calories than normal. (Eating a meal produces a thermogenic effect as your body expends energy in digestion. That's why dieters are told not to skip meals. Skipping meals lowers your metabolic rate, decreasing your calorie expenditure.) Similar studies also show that caffeine, the stimulant that gives coffee its eye-opening kick, can also boost ephedra's thermogenic properties. But before using these combinations check with a health practitioner knowledgeable about nutrition. Aspirin or salicin may cause stomach upset in some people (although salicin is generally tolerated well.) Carnitine: Lipotropic Amino Acid To get carnitine into your system, you don't have to take it as a supplement. Your body already makes this vitamin-like substance. However, your body doesn't make that much. And it is said to be especially low in people with heart disease. This non-essential amino acid (said to be non-essential because human bodies produce it) is a key ingredient in the formation of mitochondria membranes. Mitochondria are tiny structures in your cells that burn fats for energy. Consequently, sufficient carnitine is necessary for the movement of fat into the mitochondria where it is consumed. When not enough carnitine is present, the breakdown of long chain fatty acids slows down. Said to improve the recovery rate for athletes (it may limit the production of lactic acid, a waste product in muscle tissue), carnitine can also lower cholesterol levels, boost levels of HDL (the good cholesterol) and decrease serum triglycerides (blood fats linked to heart disease). Not bad for a nutrient that coaxes fat into those teeny, ceullular, mitochondrial furnaces. Go for the Chrome Chromium-based supplements work as lipotropic agents by aiding insulin use in the body. This essential trace mineral is required for normal protein, fat, and carbohydrate metabolism. According to Dr. Michael Janson, author of The Vitamin Revolution in Healthcare and President of the American Preventive Medical Association (APMA), "Chromium is important for proper insulin activity. Insulin moves sugar into the muscle cells, where it is burned off as energy. Chromium improves the activity of insulin, and since insulin causes fat deposition, less of it means less fat deposition." Chromium has also been shown to build muscle tissue and to reduce LDL cholesterol, which has been linked to heart disease. Although the body's minimum requirement is low, the American diet tends to be deficient in chromium, in part because the mineral can be difficult for the body to absorb. The fact that, in nature, chromium is most powerfully concentrated in brewer's yeast, wheat germ and liver-items most Americans rarely eat-probably hasn't helped either. Other natural sources of chromium include whole grains, molasses and beef. But it is estimated that 50% of Americans are chromium deficient. An early study found that overweight adults taking a chromium supplement lost an average of 22% body fat, while maintaining or gaining lean body mass. In another study, athletes consuming 200 mcg. of chromium a day showed an average loss of 7.5 lbs. of body fat after six weeks, without a corresponding loss of muscle tisue. Overall, although some studies question chromium's precise effects, many experts are optimistic about this substance because of its relationship to insulin in the body's metabolism. Hydroxycitric Acid (HCA) Another possible addition to the dieter's arsenal is HCA. In nature, HCA appears chiefly in a fruit called garcinia cambogia (sometimes also called Malabar tamarind or brindall berry), a citrus plant found primarily in Asia, where the rind is often used as a flavoring agent. HCA works by inhibiting the enzyme in the body responsible for converting carbohydrates into fat. HCA causes calories to be burned in an energy cycle similar to thermogenesis and acts as somewhat of an appetite suppressant. HCA is also said to have a role in reducing triglycerides and LDL cholesterol levels. Several animal studies have shown that HCA caused significant weight loss without a reduction in lean body mass. In other words, the pounds that came off came out of fat stores, and not out of energy or muscle reserves. This means that HCA takes off not just weight but body fat, making it a potentially effective tool against weight regain. Dr. Elson Haas, director of the Preventive Medical Center of Marin in San Rafael, CA, and author of Staying Healthy With Nutrition: The Complete Guide to Diet and Nutritional Medicine, believes that HCA can be a helpful aid for dieters when used in combination with eating habit changes and exercise. He recommends an HCA and chromium blend for optimum appetite suppression. "This combination can keep the appetite down and reduce sugar cravings," he says. Although human research data on HCA is still in the preliminary stages, the animal study results are positive, and the supplement seems to have minimal side effects in most people. Some Overall Recommendations You are likely to lose weight faster if you eat sensibly. This means avoiding foods high in fat or sugar (which are the most likely to add to stored body fat), but it doesn't mean starving yourself. A sensible balanced diet, along with moderate exercise, is still the best prescription for weight loss. As Dr. Haas puts it, "I'm a firm believer in diet and exercise. Using supplements responsibly can help you to lose weight provided they're combined with dietary changes and exercise. They won't work if you don't change anything." No one is suggesting that dietary supplements are a miracle cure for being overweight-as always in self-health care, there are no magic wands. But, used as directed and combined with a good diet and exercise plan, you could find that these supplements might help you work your way to a slimmer you. Mimi Facher is a freelance writer who has contributed to Prevention, Cosmopolitan and Self.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=349) The Joints Are Jumping
Date:
June 11, 2005 04:56 PM
The Joints Are Jumping by Rachel Alexander Energy Times, October 8, 2003 It usually starts with a twinge in your back or an ache in your knees: Knee stiffness, back pain and joint inflammation can signal the beginning of arthritis. According to the US Food and Drug Administration, arthritis affects over 42 million Americans-that's 1 in every 3 adults-and costs the economy nearly $65 billion annually. But as common as arthritis is, it doesn't have to extract a high cost from your joints. Who's At Risk? Arthritis literally means an "inflammation of the joints" and can affect anyone-from small children to 80-year-olds. Some groups are more prone to certain types of arthritis; for instance, those over 40 are at greater risk for developing osteoarthritis, a degenerative condition of the joints. According to Johns Hopkins Medical Institute, more than 50% of all individuals over the age of 40 have x-ray signs of osteoarthritis in weight-bearing joints (such as those in the knees and hips), and nearly half of those over 65 have measurable symptoms of arthritis. Osteoarthritis is often caused by overuse, age, excess weight or genetics, or by a combination of these factors. Rheumatoid arthritis, on the other hand, is a disease of the immune system that affects the joints, which can make it harder to diagnose because early symptoms-fatigue, weakness, loss of appetite and low-grade fever-can mimic other chronic conditions. Stiffness and pain may or may not accompany the initial symptoms of rheumatoid arthritis. However, joints eventually become inflamed and swollen. Although less common that osteoarthritis, rheumatoid arthritis affects more than 2 million Americans. Covering Up the Signs Treating arthritis can involve the use of both conventional and non-conventional therapies. "In osteoarthritis specifically, conventional medicine has just been focused on covering up the symptoms," says Jason Theodosakis, MD, author of The Arthritis Cure (St. Martin's Press). "In the history of medicine, this approach has been considered primitive." But Dr. Theodosakis points out that treatment often depends on the type of arthritis involved: "Rheumatoid arthritis patients should be taking prescription drugs that are known to prevent the disease from progressing. [Use] alternative medicine as an adjunct..." Conventional therapies often involve the use of non-steroidal anti-inflammatory (NSAID) medicines, such as ibuprofen and naproxen. The chief drawback of NSAIDs is the toll these treatments extort from the gastrointestinal system. In fact, a 2002 study conducted by researchers at the University of South Florida, Tampa, found that more than 15% of patients developed digestive problems after a five-week course of ibuprofen. In addition, ibuprofen may increase blood pressure. Newer prescription NSAIDs called COX-2 inhibitors, which work by suppressing the body's inflammatory response, also carry risks of side effects ranging from diarrhea and fluid retention to liver damage and kidney problems. In addition, people with asthma or chronic allergies (including to aspirin) should not take these medicines. Corticosteroids-another treatment option that has been used to lessen inflammation-can cause side effects such as increased appetite, mood changes and even immune system breakdown. Natural Answers A growing body of evidence shows that nutrients such as glucosamine and MSM, coupled with lifestyle changes, can help decrease or eliminate some of the aches and pains of arthritis. Glucosamine is a natural chemical that helps build joints. When the cartilage in joints deteriorates due to age or other factors, studies indicate that glucosamine provides the necessary building blocks for rebuilding and repairing this tissue. In one investigation (Archives of Internal Medicine 2002; 162:2113-23), scientists discovered that glucosamine slowed the progression of osteoarthritis and improved symptoms for over 200 patients. Another study, conducted by researchers in the Netherlands, demonstrated that a combination of glucosamine and chondroitin holds promise for conditions such as spinal disc degeneration. To date, several studies have confirmed glucosamine's ability to help the symptoms of arthritis, and the National Institutes of Health is currently supporting research to further study the benefits of glucosamine. Other Joint Aids MSM is often an adjunct therapy as it does not work directly on joints, but provides the raw materials, in this case sulfur, to help rebuild cartilage in the joint matrix. Studies indicate that sulfur has a protective effect and may interact with magnesium, an essential bone nutrient. Traditionally, the herb horsetail (Equisetum arvense) has been used to supply silica, a mineral component of nails, bones and joints. Its support of these structures can help in the fight against arthritis. As the body ages, it may lose much of its silica reserves. Resupplying much of this mineral may help support joints. In addition, experts believe, silica can help the body use calcium more effectively and support bone health. Since rheumatoid arthritis is a systemic affliction, you should work with a trained health professional in treating it. Complementary care practitioners often use antioxidant nutrients, such as vitamins C and E, to reduce free radical damage, along with pantothenic acid (vitamin B5) to lessen morning stiffness. A Joint Project According to Dr. Theodosakis, exercise is the key to dealing with arthritis: "[Start with] an individualized exercise program that strengthens the joints without causing more damage...and an eating program to control your weight if you are currently overweight." To limit the effects of arthritis, you should quit smoking, since smoking generates free radicals that can harm the tissues which make up joints. In addition, a strict vegan diet may help alleviate some of the pains of rheumatoid arthritis. Dr. Theodosakis also recommends looking for hidden causes of symptoms, such as food allergies, that may contribute to arthritis. Heat helps ease arthritis pain and encourages both blood flow and tissue repair. A plain, old-fashioned hot water bottle works quite well. Or you can use one of the newer heat-generating wraps, which are thin enough to be worn under clothing and don't have to be constantly reheated. You can't always avoid arthritis, especially as you get older. But you don't have to let it get the better of you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=292) Red Yeast Rice For Lipid Wellness
Date:
June 04, 2005 02:30 PM
Maintaining cardiovascular health is a fundamental strategy in the holistic healing system. It may be the most important thing you can do for your body. One of the factors for optimal cardiovascular health is keeping your lipid levels within the normal range. But with today’s fast-paced lifestyle, it’s hard to maintain a healthy diet and exercise program. Red yeast rice is a natural product that supports maintenance of normal lipid levels. Source Naturals RED YEAST RICE is standardized to 1.5% mixed mevinolinic acid monacolins. These monacolins block the synthesis of lipids in the liver by binding to the lipids production enzyme HMG-CoA reductase. Support your lipid wellness with the quality and science of Source Naturals RED YEAST RICE. The Liver and Lipid The amount of lipid you consume in food is not the most important factor for regulating normal lipid levels. The liver manufactures approximately 80% of total body lipid while the other 20% comes from dietary sources. Our bodies require lipid but we can also get too much of it. Lipid is only harmful to us if it becomes oxidized. Oxidized lipid can cause damage to tissues and accumulate in blood vessels. Balancing the lipid produced by your liver is critical to your total lipid and your cardiovascular health. Red yeast rice has been used in China for centuries to make rice wine, to color and flavor foods such as Peking duck and as a health promoting food. It is prepared by fermenting a type of yeast (Monascus purpureus) over rice. Red yeast rice is a complex product that contains several active ingredients including monacolins. Monacolins act as HMG-CoA inhibitors. HMG-CoA reductase is an enzyme that helps make lipid. By blocking its lipid producing action, the natural compounds in red yeast rice can help you maintain lipid levels that are within the normal range. A double blind clinical trial using red yeast rice and placebo with 80 human subjects was conducted at UCLA. After eight weeks with no changes in diet composition the group taking red yeast rice maintained healthy lipid levels. Natural Support For Your Heart Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Taking personal responsibility for your health is at the heart of the wellness revolution. Changing your lifestyle is one of the most effective ways to take that responsibility and provide support and protection for your heart. A diet low in lipid, saturated fats and trans-fatty acids, and high in complex carbohydrates and fiber is important. Exercise regularly, quit smoking and supplement your diet with heart-healthy compounds such as red yeast rice, CoQ10, folic acid, garlic, omega-3 fatty acids, carnitine, hawthorn berry extract, arginine, vitamin E and tocotrienols. Source Naturals RED YEAST RICE is standardized to 1.5% mixed mevinolinic acid monacolins. This standardization process provides you with the assurance that you are getting a consistent concentration of these compounds in each dose. RED YEAST RICE is part of Source Natural’s extensive line of products scientifically formulated to provide support for your cardiovascular health.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=191) CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest
Date:
June 01, 2005 09:59 AM
Standard pharmaceutical drugs came into common use only around the turn of the century. Before that, herbal preparations were administered for health concerns. Today, in nearly every country in the world, herbs are used by health care practitioners as the focal point of health care. Only in the United States is the otherwise widespread use of herbs missing in mainstream culture. But now modern scientific investigation is confirming the benefits of herbal supplementation, which is paving the way for us to reclaim and implement herbs into our everyday lives.
The primary need for preserving the rainforestsRain Forest Herbs Scientists’ knowledge of the varied rain forest flora is far from complete. The plants which have been thus far identified are so elaborate in molecular structure that it’s difficult to understand how these molecules function, let alone how to reproduce them. What is known is that the biodiversity of the rain forest yields numerous biologically active plant constituents which can have a profound influence on supporting the body through times of imbalance. Preserving the rain forest means preserving these precious herbs and the unique constituents contained within them.
Cat’s Claw Defense Complex contains powerful rainforest herbsA Synergistic Blend Source Naturals CAT’S CLAW DEFENSE COMPLEX harnesses the power of some of the most complex botanicals on earth into a synergistic blend of defense-enhancing herbs, each with a unique set of compounds which complement the body’s natural physiology. Source Naturals CAT’S CLAW DEFENSE COMPLEX is the first step in the rediscovery of a long-standing herbal tradition. Source Naturals was the first full-line supplement company to introduce the herbal superstar, Cat’s Claw, and the first to offer it in a combination formula. CAT’S CLAW DEFENSE COMPLEX provides 2000 mg of Cat’s Claw per four tablets – more than many companies’ single ingredient Cat’s Claw products! It combines powerful rain forest herbs like Pau D’Arco and Western herbs such as Aloe Vera and St. John’s Wort with legendary Chinese herbs (Reishi Mushroom and Astragalus). Source Naturals Cat’s Claw Defense Complex also includes two categories of antioxidants for broad spectrum support.
How we ensure quality and potencyCat’s Claw & Pau D’Arco – Peruvian Jungle Discoveries Cat’s Claw was discovered in the depths of the Peruvian Amazon jungle. Researchers have discovered that components extracted from the herb can bolster the body’s innate defenses, address discomforts associated with stress, and support intestinal health. Source Naturals uses only the highest quality Cat’s Claw inner bark – which is at least twenty years old, the amount of time it takes the bark to reach its peak biological activity– and uses a careful process to insure that harvesting the bark doesn’t weaken or destroy the plant. Like all of our herbs, each shipment of Cat’s Claw is also routinely inspected and tested by a trained herbalist to ensure maximum quality and potency. Pau D’Arco is also native to the South American rain forest and, like Cat’s Claw, has a high concentration of active constituents – a combination of anthraquinones and naphthoquinones, primarily lapachol – in the bark of the plant. Each daily dosage of CAT’S CLAW DEFENSE COMPLEX contains 100 mg of Pau D’Arco bark and 100 mg of concentrated Pau D’Arco bark extract for broad spectrum support. Herbs — Adaptogens for Balance Of the Chinese herbs, Siberian Ginseng is one of the best known adaptogens. Adaptogens have a balancing effect, helping us adapt to increased stress levels and other changes, like different altitudes or time zones. Thus, supplementation with Siberian Ginseng can help prevent stress-related health concerns. Schizandra, a small creeping vine with red berries, is a Chinese adaptogen which helps regulate the body’s functions and cleanse it of toxins.
Herbs that energize the body and build resistance to impaired bodily functionThe trio of Chinese mushrooms – Reishi, Shiitake, and Maitake – has been used by Chinese herbalists for centuries, and provides the highest quality natural support for the body’s defenses. Modern science has revealed the true power behind Reishi, Shiitake, and Maitake: high levels of polysaccharides – long chain sugar macromolecules which are known for their protective and cleansing abilities. CAT’S CLAW DEFENSE COMPLEX utilizes only the mycelia biomass of Reishi (200 mg), Shiitake (200 mg), and Maitake (150 mg) to ensure the highest level of activity. Astragalus is the premier tonic – or internal strengthener – of Chinese herbalism. In addition to helping energize the body, Astragalus also builds resistance to weakness and to impaired bodily function. Isatis is a cooling herb which has been shown to have a broad spectrum inhibitory action in in-vitro studies, and helps support normal liver function. Used for thousands of years, the aloe plant has been treasured for its varied uses both externally and internally. Aloe Vera juice is high in mucopolysaccharides, which have been found to have powerful protective capabilities. CAT’S CLAW DEFENSE COMPLEX provides 200 mg of aloe (200:1 concentration) extracted from the whole leaf of the plant.
Why St. John’s Wort is powerful and usefulIt is generally agreed that hypericin and pseudohypericin, two bioflavonoids which are the active constituents in St. John’s Wort, probably act as monoamine oxidase (MAO) inhibitors, which current research has shown are powerful as internal cleansing agents. St. John’s Wort is particularly useful because of its ability to cross the Blood-Brain Barrier, through which many elements are unable to pass.
The liver’s health is essential because of its responsibility for over 500 different functionsAntioxidants and Plantioxidants – Supporting Complete Health Source Naturals CAT’S CLAW DEFENSE COMPLEX includes key liver-supporting antioxidants like Zinc, Beta Carotene, and Vitamin C – nutrients that help protect the liver from stress and pollution induced free radical damage. These three nutrients are also wellknown for their ability to help strengthen the body’s resistance and move through imbalances quickly. The liver is responsible for over 500 functions, including converting vitamins to their active forms, and processing and eliminating waste products from the body; therefore its health is vital. Plantioxidants™ is Source Naturals’ term for Plant-Derived Antioxidant Bioflavonoids. Though most people are only aware of the vitamin and mineral antioxidants, the latest scientific research has indicated that the plant kingdom may provide the most potent antioxidants in the world. Plants, trees, and citrus fruits all contain bioflavonoids (also called polyphenols) – a large group of restorative compounds with similar chemical structures which help protect the body from the ravages of oxidative damage due to free radicals. Some of the Plantioxidants included in CAT’S CLAW DEFENSE COMPLEX are: Quercetin, which helps inhibit the body’s sensitivity to dangerous particles in the air; Proanthodyn, which promotes tissue repair by helping to strengthen collagen and elastin, the two primary structural components in cartilage; Silymarin, which promotes liver-tissue regeneration and optimizes liver-cell function; Green Tea, a remarkably potent antioxidant; and Ginkgo, which is renowned for helping transport oxygen to the brain.
The way to naturally bolster the body’s defensesA Holistic Natural Answer The natural world provides us with a seemingly endless supply of complex herbal compounds with unreplicable and unique constituents so varied and numerous that most doctors aren’t even aware of their existence. Source Naturals would like to change that with CAT’S CLAW DEFENSE COMPLEX – the natural way to bolster the body’s innate defenses. All the ingredients included are at optimal potencies, and in the forms best absorbed by the body. The result? The most powerful, holistic product available to help maintain the structure and function of the natural defenses – Source Naturals CAT’S CLAW DEFENSE COMPLEX.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=130) Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
Date:
May 24, 2005 09:52 AM
Cognitive Improvement in Mild to Moderate Alzheimer's Dementia After Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Maria De Jesus Moreno Moreno, MD Instituto Nacional de la Senectud, Mexico City, Mexico
in both men and woman they consistently improved after 90 and 180 days versus baseline with adiministration of GPC three times a day, whereas in the placebo group they remained unchanged or worsened. Statistically significant differences were observed between treatments after 90 and 180 days. Keypoints: references: Bartus RT, Dean RL III, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction, Science. 1982;217:408-414. 2. Larson EB, Kukull WA, Katzman RL. Cognitive impairment: Dementia and Alzheimer's disease. Annu Rev Public Health. 1992;13:431-449. 3. Hofman A, Rocca WA, Brayne C, et al, for the European Prevalence Research Group. The prevalence of dementia in Europe: A collaborative study of 1980-1990 findings. Int d Epidemiol. 1991;20:736-748. 4. Blackwood W, Corsellis JAN, eds. Greenfield's Neuropathology. 3rd ed. London: Arnold; 1976. 5. Geldmacher DS. Cost-effective recognition and diagnosis of dementia. 5emin Neurol. 2002;22:63-70. 6. Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459. 7. Perry EK. The cholinergic hypothesis--ten years on. Br Med Bull. 1986;42:63-69. 8. Giacobini E. From molecular structure to Alzheimer therapy. Jpn d Pharmacol. 1997;74:225-241. 9. Giacobini E. Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: From tacrine to future applications. Neurochem Int. 1998;32:413-419. 10. Brinkman SD, Smith RC, Meyer JS, et al. Lecithin and memory training in suspected Alzheimer's disease. J Gerontol. 1982;37:4-9. 11. Davis E, Emmerling MR, Jaen JC, et al. Therapeutic intervention in dementia. Crit Rev Neurobiol. 1993;7:41-83. 12. Amenta E Parnetti L, Gallai V, Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropiate approaches? Mech Ageing Dev. 2001;122:2025-2040. 13. Sigala S, Imperato A, Rizzonelli P, et al. k-Alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eurd Pharmacol. 1992;211:351-358. 14. Govoni S, Battaini E Lucchi L, et al. Effects of alpha-glycerylphosphorylcholine in counteracting drug-induced amnesia: Through cholinergic and non-cholinergic mechanisms [in Italian]. Basi Raz Ter. 1991;21:75-78. 15. Canonico PL, Nicoletti F, Scapagnini U. Neurochemical and behavioral effects of alpha-glycerylphosphorylcholine [in Italian]. Basi Raz Te~ 1990;20: 53-54. 191 CLINICAL THERAPEUTICS ® 16. Parnetti L, Amenta E Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: An analysis of published clinical data. Mech Ageing Dev. 2001;122:2041-2055. 17. Venn RD. The Sandoz Clinical Assessment-Geriatric (SCAG) scale. A general-purpose psychogeriatric rating scale. Gerontology. 1983;29:185-198. 18. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991;19:330-341. 19. Frattola L, Piolti R, Bassi S, et al. Multicenter clinical comparison of the effects of choline alphoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia. Curt Ther Res Clin Exp. 1991;49:683-693. 20. Muratorio A, Bonuccelli U, Nuti A, et al. A neurotropic approach to the treatment of multi-infarct dementia using L-c~-glycerylphosphorylcholine. Curt Ther Res Clin Exp. 1992;52:741-75l. 21. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: APA; 1994. 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. 23. Folstein ME Folstein SE. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198. 24. Loeb C, Gandolfo C. Diagnostic evaluation of degenerative and vascular dementia. Stroke. 1983;14:399-401. 25. Hamilton M. A rating scale for depression.J Neurol Neurosurg Psychiatry. 1960;23:56-62. 26. Hamilton M. Development of a rating scale for primary depressive illness. BrJ Soc Clin Psych& 1967;6:278-296. 27. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. AmJ Psychiatry. 1984;141:1356-1364. 28. Reisberg B, Ferris SH, De Leon MJ, et al. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry. 1982;139:1136-1139. 29. National Institute of Mental Health. Clinical global impressions. In: Guy W, ed. ECDEU Assessment for Psychopharmacology. Revised edition. Rockville, Md: National Institute of Mental Health; 1976:217-222. 30. Burns A, Russell E, Page S. New drugs for Alzheimer's disease. Br J Psychiatry. 1999;174:476-479. 31. Kumar V, Anand R, Messina J, et al. An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors. Eur J Neurol. 2000;7:159-169. 32. Knapp MJ, Knopman DS, Solomon PR, et al, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991. 192 M. Moreno 33. Lindstrom MJ, Bates DM. Newton-Rapshon algorithms for linear-mixed effects models for repeated measure data. J Am Stat Assoc. 1998;83:1014-1022. 34. Thai LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology 1996;47:705-711. 35. Rogers SL, Friedhoff LT, for the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303. 36. Rogers SL, Doody RS, Mohs RC, Friedhoff LT, for the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158:1021-1031. 37. Corey-Bloom J, Anand R, Veach J, for the ENA 713 B352 Study Group. A randomized trial evaluating the efficacy and the safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1:55-65. 38. Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. BMJ. 1999;318: 633-638. 39. Amenta E Bronzetti E, Del Valle M, Vega JA. Effects of alpha-glycerylphosphorylcholine in neuroanatomy of aging brain in experimental animals [in Italian]. Basi Raz Te~: 1990;20:31-38. Address correspondence to: Scientific Department, Italfarmaco SpA, via dei Lavoratori 54, 20092 Cinisello Balsamo, Milan, Italy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=98) Niacin and Cholesterol -- abstracts states blocks cholesterol absorption ...
Date:
May 21, 2005 11:20 AM
The Era of Statins - Is There Still a Place for Other Classes of Lipid-Lowering Drugs? Wascher, Thomas C. Department of Internal Medicine, Diabetes and Metabolism Unit, and Diabetic Angiopathy Research Group, Medical University of Graz, Graz, Austria. HeartDrug (2005), 5(1), 34-38. CODEN: HEARCO ISSN: 1422-9528. Journal; General Review written in English. CAN 142:384798 AN 2005:64730 CAPLUS Abstract A review. Plenty of evidence suggests statins as the first-line therapy for the treatment of lipid disorders. However, further therapeutic options available in the treatment of lipid disorders are fibrates, niacin and cholesterol absorption inhibitors. In the present study, current treatment modalities of lipid disorders are reviewed, and their use was scrutinized based on the available evidence.
Niacin and cholesterol: role in cardiovascular disease (review). Ganji, Shobha H.; Kamanna, Vaijinath S.; Kashyap, Moti L. Atherosclerosis Research Center, Department of Veterans Affairs Healthcare System, Long Beach, CA, USA. Journal of Nutritional Biochemistry (2003), 14(6), 298-305. CODEN: JNBIEL ISSN: 0955-2863. Journal; General Review written in English. CAN 139:291534 AN 2003:542279 CAPLUS Abstract A review. Niacin has been widely used as a pharmacol. agent to regulate abnormalities in blood plasma lipid and lipoprotein metab. and in the treatment of atherosclerotic cardiovascular disease. Although the use of niacin in the treatment of dyslipidemia has been reported as early as 1955, only recent studies have examd. the cellular and mol. mechanism of action of niacin on lipid and lipoprotein metab. The beneficial effects of niacin in decreasing triglyceride and apolipoprotein-B contg. lipoprotein (VLDL and LDL) levels are mainly due to decreased fatty acid mobilization from adipose tissue triglyceride stores and inhibition of hepatocyte diacylglycerol acyltransferase and triglyceride synthesis, leading to increased intracellular apolipoprotein-B degrdn. and subsequent decreased secretion of VLDL and LDL particles. The mechanism of action of niacin to raise HDL levels involves decreasing the fractional catabolic rate of HDL-apolipoprotein A-I without affecting its biosynthetic rates. Niacin selectively increases blood plasma levels of Lp-AI (HDL subfraction without apolipoprotein A-II), a cardioprotective subfraction of HDL in patients with low HDL levels. Using human hepatocytes (Hep G2 cells) as an in vitro model, recent studies indicate that niacin selectively inhibits the uptake/removal of HDL-apolipoprotein A-I (but not HDL-cholesterol ester) by hepatocytes, thereby increasing the capacity of retained HDL-apolipoprotein A-I to augment cholesterol efflux through reverse cholesterol transport pathway. The data provide evidence extending the role of niacin as a lipid-lowering drug beyond its dietary role as a vitamin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=89) Bee Propolis may limit production of DHT...
Date:
May 17, 2005 05:00 PM
Chrysin controls aromatase activity, and thus the production of estradiol and estrone, and provides an alternative embodiment of this invention. This embodiment may further comprise a substance that controls 5-alpha-reductase and its production of DHT. Other aromatase inhibitors include substituted androstenediones. There is also evidence that aromatase is involved in the production of DHT, which is well known for its negative effects on the prostate and male pattern baldness. An in vitro rat testis cell suspension model was used to investigate the metabolism of tritiated testosterone, dihydrotestosterone, and androstenedione. In the presence of aromatase inhibitors and androstenedione, the metabolism was shifted towards 17-keto forms. This suggests that androstenedione and the derived aromatase inhibitors activate the 17 .beta.-hydroxysteroid-dehydrogenase in a product-activating manner. Thus, aromatase inhibitors may regulate the intratissular levels, not only of estrogens, but also of other hormonally active steroids like DHT and 5-androstenedione. Schroder et al., 31(4B) J. STEROID BIOCHEM. 685-90 (1988). Because of the usefulness of inhibiting aromatase in breast cancer patients, several synthetic aromatase inhibitors have been developed. See, e.g., U.S. Pat. No. 4,954,446. There are natural substances, however, such as chrysin, that have similar activity. Chrysin is a bioflavonoid found in propolis (bee pollen) and honey that has been demonstrated to be as potent and effective in inhibiting aromatase as the popular pharmaceutical, aminoglutethimide (AG). In aromatase enzyme assays, chrysin, 7,8 benzo-flavone (ANG), AG, flavone and genistein 4'-methyl ether (5,7-dihydroxy-4'-methoxyisoflavone, Biochanin A) were shown to inhibit aromatase. Chrysin and AG inhibited the enzyme by 50% at a concentration of 4.6 .mu.M and 7.4 .mu.M, respectfully, and only ANG had a high I.sub.50 of 0.5 .mu.M. Both Flavone and Biochanin A inhibited aromatase, but to a lesser degree. Campbell et al., 46(3) J. STEROID BIOCHEM. MOL. BIO. 381-88 (1993). In screening for potential chemopreventives against cancer, chrysin was one of the three of flavonoids with the greatest aromatase-inhibiting activity, with an inhibitory concentration (IC) of 1.1 .mu.g/mL. Jeong et al., 22(3) ARCHIVES PHARMA. RES. 309-12 (1999).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=66) Composition and Method of increasing Testonsterone...
Date:
May 17, 2005 04:01 PM
Composition and method for increasing testosterone levels Abstract This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites. May reduce DHT: By using velvet deer antler along with the testosterone and nor-testosterone precursors, the antler promotes youth film testosterone levels while balancing and ameliorating dangerous spikes in these levels. Another embodiment of the invention includes herbs that inhibits 5-alpha-reductase reducing undesirable levels of dihyrotestosterone. Another embodiment includes chrysin, which inhibits aromatase and the production of estrogenic steroids. Deer antler (called Rokujo in Ancient Chinese Medicine) is used for its sexual-reinforcing and anti-aging actions. Wang et al., 36(7) CHEM. PHARM. BULL. 2587-92 (1988). Velvet antler is living tissue that grows at a rate of up to 2 cm/day in some species. Cartilage, bone and support tissues such as nerves, blood vessels and hair follicles of the antler also evidence accelerated growth. Antler is the only mammalian organ that regenerates. These features, responsible for the accelerate growth of velvet antler are likely to be caused by either unique regulatory substances or substances found in other tissues but at lower levels. It is believed that factors actually responsible for the rapid regeneration of the velvet antler can explain the powerful health benefits of the product. Specifically, velvet deer antler regulates the adrenal cortex and energy metabolism, promotes sexual function and growth, and strengthens resistance. Its functions fall into the major categories of general body strengthening, healing, promoting blood cell growth and improving immune and cardiovascular function.
Some of velvet deer antler's key ingredients include lysophosphatidyl choline, with hypotensive activity, phosphatidyl ethanolamines, sphingomyelin, phosphatidyl choline hypothanthene and uridene, with monoamine oxidase (MAO)-inhibiting and anti-aging effects; polyamines spermine, spermidine and putrescine, with RNA polymerase stimulating effects; gangliosides that may promote memory and learning; and anti-inflammatory amino acids. A wide variety of growth factors are also found in velvet, and may be associated with its growth-promoting activity. Tsujibo et al., 35(2) CHEM. PHARM. BULL. 654-59 (1987). As taught by ancient Chinese medicine, deer antler tonifies the yang, primarily deficient yang of the kidneys, spleen and heart. Because kidneys are the seat of the basal yang, the most important use of this class of herbs is to tonify the kidney yang, whose principal manifestation of deficiency is systemic exhaustion. Yang deficiency causes impotence, spermatorrhea, watery vaginal discharge, infertility, enuresis, polyuria, wheezing and daybreak diarrhea. Patients with deficient kidney yang very often have decreased plasma thyroid hormone binding proteins, 24-hour urinary 17-ketosteroids, and decreased rate of glycolysis. When treated with tonifiers such as deer antler, these measurements return to normal ranges. BENSKY ET AL., CHINESE HERBAL MEDICINE, MATERIA MEDICA, REVISED EDITION Eastland Press, Seattle, Wash. (1993).
Deer Antler Velvet Full Spectrum Planetary Formulas 30CtDeer Antler Velvet Full Spectrum 60ct
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=62) Block the Absorption of Carbs in the intestinal track.
Date:
May 17, 2005 02:39 PM
Carb-X™ dietary supplement features 600 mg white kidney bean extract, along with 200 mg wheat inhibitor extract, per two capsules. Both extracts have been studied for their potential ability to support the inhibition of amylase, the enzyme created by the body to break down sugars and carbohydrates. Amylase inhibitors bind and inactivate this enzyme so carbohydrates and sugars pass through without breaknig down. Carb-X ™ dietary supplement formula is a new revolutoinary aid to dieting. When combined with the NaturalMax® Diet Plan, it can help decrease calories from carbohydrates.
Carb X from Natural max 90ctCarb X from Naturalmax 60ctCarb X Shake mix ChocolateCarb X Shake Mix VannillaCarb X with MCT Oil 60ctCarb X Chewables 30ct
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=61) Important Information for Allergy Sufferers
Date:
May 13, 2005 09:52 AM
Important Information for Allergy SufferersRichard Conant, L.Ac. C.N.Imagine you are one among millions who greet each spring with worry about the flood of pollen that fills the air this time of year. When the pollen season arrives, as it inevitably does, you find yourself with two choices. You can either take over-the-counter antihistamines and put up with unpleasant side-effects, or endure the sneezing, runny nose, itchy, watery eyes and other discomforts of hay fever. If there was a natural ingredient, a nutritional substance found throughout nature in many foods and plants, that could offer an alternative, would you not be interested? Quercetin, one among hundreds of flavonoids found throughout the plant kingdom, is this ingredient. Quercetin has been researched in numerous pharmacological studies. The results of this work strongly suggest that quercetin helps to stabilize the fundamental process in the body which causes an allergic reaction. Quercetin, as shown in test-tube ("in vitro") studies, prevents the release of histamine from "mast cells," immune cells that stand guard in the tissues which meet the outside environment—the nasal passages, the lungs, the digestive tract and skin. While this has yet to be confirmed by human clinical trials, in the picture that emerges from the research so far, quercetin looks like a rescue nutrient for allergy sufferers. Reports from Quercetin Users I have seen numerous reports from individuals who have indeed achieved significant reductions in allergic sensitivity by using quercetin. And this includes food allergies as well as environmental allergies. Anecdotal stories like these carry little weight among scientists, because they do not provide evidence that the observed result will be repeated in other cases. Only placebo-controlled, double-blind studies can produce this kind of scientific proof. Yet, when anectodal evidence (this includes physician "case reports") correlates with the results of pharmacological research such as we have on quercetin, I believe it should be taken seriously. And quercetin is a nutrient that works effectively when taken as a dietary supplement. For example, one gentleman writes that his wife, who is allergic to pollen and dust, is now "sneeze-free" after using quercetin for three years. A Pennsylvania woman writes that her husband, also a long time allergy sufferer, "seems to be nearly allergy free" after one month of use. Another man says that "quercetin has literally changed my life." These are not isolated cases; a respected nutritionist who specializes in allergies and environmental problems has seen many similar outcomes with a quercetin. Clearly something significant is going on with respect to quercetin as a nutritional approach for overcoming allergies. Bear in mind, though, that quercetin does not function like an antihistamine medication; it is not a quick fix. As a nutrient that helps to normalize body functions naturally, quercetin needs time to work, and should be taken for at least two or three weeks to achieve these results. Quercetin Quiets the Allergic Response Exerting a broad range of biological effects, quercetin is perhaps the most active and versatile flavonoid. In test-tube studies, quercetin acts directly on the mast cell in a way that quiets the allergic response. An allergic reaction occurs when IgE antibodies, positioned on the mast cell surface, come in contact with a potential allergy-causing substance like pollen. The mast cell is then signaled to release histamine from storage granules located inside the cell, through a process called "degranulation." The histamine circulates throughout the body, causing the runny nose, itching and other discomforts associated with allergies. Quercetin stabilizes mast cell membranes, in effect turning down the allergic response signal. Quercetin also slows other mechanisms which are involved with inflammation, such as the production of inflammatory prostaglandins and leukotrienes. This adds to its membrane-stabilizing effect, and its value in allergy control. Quercetin appears to substantially raise the threshold for initiation of an allergic reaction. In allergy sufferers this threshold is low, for reasons which are not well understood. They may have more IgE antibodies than normal, making the mast cells overly "trigger happy." Histamine has its proper place in the immune response that defends us against truly harmful foreign substances in the body. But like many chemicals produced by the body, histamine is a two-edged sword. In allergy-prone individuals, the mast cells have become overreactive, releasing too much histamine, unnecessarily. With quercetin in the bloodstream, histamine release from mast cells is kept under control. Quercetin's ability to down-regulate both the inflammatory and allergic responses makes it, I believe, a highly important nutrient for humans to consume on a regular basis. Quercetin-the Scientific Evidence Several studies, published in respected journals such as the Journal of Allergy and Clinical Immunology and others, have demonstrated quercetin's ability to control the release of histamine from mast cells. (Quercetin has the same effect on basophils, a type of white blood cell that also contains histamine.) In these experiments, mast cells taken from both animals and humans are exposed in the test tube to various substances—called "antigens"— that stimulate histamine release. The researchers then add an inhibiting agent such as quercetin to the mixture and measure the differences in histamine output. Quercetin has shown itself to be one of the more powerful histamine inhibitors, more powerful, in fact, than disodium cromoglycate, an anti-asthma drug. Quercetin has other beneficial properties. A strong antioxidant, Quercetin has a higher level of antioxidant activity than both vitamin C and vitamin E. (Quercetin enhances the antioxidant activity of vitamin C; quercetin and vitamin C are true synergists.) Quercetin has been shown to block the oxidation of LDL cholesterol by free radicals. Quercetin also protects cell membranes from being injured by oxidized LDL. The damage that oxidized LDL causes to the delicate membranes of blood vessel linings allows plaque deposits to form, setting the stage for atheroslcerosis. These observations point to quercetin as a key nutrient for maintaining cardiovascular health.
Like all flavonoids, quercetin is not classified as an essential nutrient, although flavonoids were once called "Vitamin P." In view of its many beneficial actions, quercetin is a nutrient that clearly has important roles to play in human nutrition, for allergy sufferers, and for everyone.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=47) Nattokinase: Food For Cardiovascular Health
Date:
May 10, 2005 10:13 AM
Say it Ain't Soy! Yes, but this soybean is different! What makes it different is simple. after hours of fermentation, the boiled soybean metamorphose to an ancient medicinal food called "Natto" pronounced "Nah'-Toe." Natto may just be the "perfect food," producing 18 valuable amino acids and an enxyme natokinase that may challenge the pharmaceutical industry's best "blood-clot busters." Natto, which has recently attracted attention throughout the world, is the third most popular type of fermented soybean in the japanese diet. Japan has the highest average longevity in the world, which may partly be attributed to a high consumption of natto. When compared with ordinary soybeans, the natto produces more calories, protein, fiber, calium, potassium and vitamin B2. Its high protein and economical price in terms of protein per gram has earned it the sobriquet. "Hata-ke no niko," a meat of the field. This nickname appears well deserved, as in comparison with an equivalent amount of beef, natto has slighly less protein (16.5 grams to 21.2 grams),but contains more carbohydrates and fiber, and is also higher in calcium, phosphorous, iron and vitamin B2. Plus, it has nearly double the calcium and far more vitamin E to boot. According to legend, the first person to originate traditional Japanese natto was the famous warrior Yoshiie Minamoto during the Heian era of Japanese history (794 - 1192 A.D.). The horse was extremely important to the Japanese samurai warrior of the period, and great care was given to provide suitable provisions for the horses when armies were on the move. Typically, boiled soybeans were cooled down, dried in teh sun and packed immediately in rice straw bags for transport with the army. If the army was on a rapid deployment, the boiled soybeans were packed hastely into the rice straw bags with out cooling or drying. The rice straw just happened to contain a harmless and naturally occuring microorganism, Bacillus Subtilis that fermented the soybeans and producted natto with its characteristic sticky texture. Initially, the soybeans were presumed to have spoiled until yashiie minamoto observed that his horses were "picky eaters" and demonstrated a preference for the "spoiled" Soybeans or natto. One day, Minamoto demonstrated tremendous courage and dipped his fingers into the seemingly rotten goo. To his astonishment, the fermented soybeans were not only edible but had a distinct umami flavor. Minamoto was responsible for introducing natto to northwestern Japan, where he ruled. To this day natto is especially popular in that region of Japan as a folk remedy for fatigue, beriberi, dysentery, heart and vascular deseases. The most distinctive features of natto are the adheasive surrounding the soybeans and the strong flavor. The sticky material has been shown to consist of poly-g-glutamic Acid (D and L) and polysaccharides (Levan-form fructan), and the strong "cheese like" flavor is due to the presence of pyrazine. These features sometimes make it hard for some people, especially people from other countries, to accept natto; however, these are the main factors which give natto the outstanding properties. Natto, which has recently attracted attention throughout the world, is a familiar part of the Japanese diet. Technical Aspects of Nattokinase: Nattokinase produces a prolonged action in two ways: it prevents the formation of thrombi and it dissolves existing thrombus. Nattokinase orally administrated to twelve healthy adults indicated elevations in the breakdown products of the fibrin and the ability of the blood to break down fibrin called eugobulin fibrionlytic activity (EFA). These results suggest the ability of nattokinase to accelerate fibrinolysis in the blood for a prolonged period of time. FDP levels in the adults drastically increased 4 hours after the administration of the nattokinase, indicating that fibrin within the blood vessels is gradually being disolved with repeated intake of nattokinase. By measuring the EFA & FDP levels, the activity of nattokinase has been determined to last for 8 to 12 hours. An additional parameter for confirming the action of NATTOKINASE following oral administration is a rise in blood levels of tissue plasminogen activator (TPA) antigen, which indicates a release of TPA from the endothelial cells and/or the liver and the endogenous production of plasmin (The body's blood clotting buster).6,7 In 1995, researchers from Miyazki Medical College and Kurashiki Unerversity of science and arts in Japan studied the effects of nattokinase on the blood preasure in both animals and human subjects. In addition, the researchers confirmed the presence of inhibitors of angiotensin converting enzyme (ACE) within the test extract, which consisted of 80% ethanol extract of lyophilized viscous materials of natto. ACE causes blood vessels to narrow and blood pressure to rise - by inhibiting ACE; nattokinase has a lowering effect on blood pressure.1,2 The same natto extract was then tested on human volunteers with high blood pressure. Blood pressure levels were measured after 30 grams of lyophilized extract (Equivalent to 200 grams of natto food) was administered orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure (SBP) decreased on average from 173.8+- 20.5 mmHg to 154.8+-12.6 mmHg. Diastolic blood pressure (DBP) decreased on average from 101.0+- 11.3 mmHg to 91.2+- 6.6 mmHg. On average, this data representes a 10.9 percent drop in SBP and a 9.7 precent drop in DBP. 1,2,6 Disclaimer: The above artical is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competen t licensed professional health care provider. The information in this artical has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any desease.
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Date:
May 09, 2005 06:10 PM
It's in the BloodNatural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul BubnyThe National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen. “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks. “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).” At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke. While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!” Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.” And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.” Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.” King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.” Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.
"Blur of Products"With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.” To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following: Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent. Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels. Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.” “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.” On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone. Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients. Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs. Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic. Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action. Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.” Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take. “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels. Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids. Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period. “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake. For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.” Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients. Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO. Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols. Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol. Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky. “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.” Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.” Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said. However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.” Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.” Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols. Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”
New WeaponsThere are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise. With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.” Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM. “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/
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What is a broccoli?
Kava kava can be used to treat depression and anxiety, largely due its content of kavalactones that are believed to increase the amount of a number of neurotransmitters in the blood, including the feel-good neurotransmitter serotonin. 
Passion flower has been used for centuries to treat anxiety, stress and depression, its active ingredients believed to be maltol and ethylmaltol that help to increase the level of gamma-aminobutyric acid (GABA) in the brain. GABA is one of the brain's key neurotransmitters and has been described by some as the brain's own 'Valium' supply. 
Bromelain enzyme may not be as familiar as other digestive supplements to most people but this helpful catalyst offers a wide range of benefits not only to the digestive system but also to other systems of the body. 
