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  Messages 1-50 from 51 matching the search criteria.
Andrographis Darrell Miller 7/30/19
Ten powerful anti-inflammatory herbs VitaNet, LLC Staff 8/30/18
Regular consumption of nuts may improve male fertility Darrell Miller 7/5/18
CBD Oil Benefits for Dogs Darrell Miller 2/17/18
6 Natural Remedies To Cleanse Your Congested Colon Darrell Miller 2/10/18
Olive Oil With Lemon In The Morning Can Do Wonders To Your Body Darrell Miller 9/21/17
Treat Your Arthritis Problems With Gelatin Amazing!! Darrell Miller 6/4/17
Tips for Keeping Your Joints in Top Shape Darrell Miller 5/14/17
These raised bed gardening tricks beat traditional gardening every time Darrell Miller 3/29/17
Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis Darrell Miller 3/22/17
How to strengthen your bones Darrell Miller 12/10/16
Maca Root And Your Health Darrell Miller 9/28/16
Boswellia - The Anti-Inflammatory Herb Darrell Miller 7/23/15
Can Celadrin Help Joint Pain? Darrell Miller 3/5/14
How Do You Reduce Arthritis Naturally? Darrell Miller 12/5/13
Boswellia Can Help you to Reduce all type of Inflammation Pain Darrell Miller 11/6/13
Can The Consumption of Collagen Help Hair, Skin, Nails, And Joints? Darrell Miller 5/30/13
The Amazing Health Benefits of Curcumin Darrell Miller 4/19/12
What Are the Health Benefits Of Collagen Tablets? Darrell Miller 4/10/12
How Does Methylsulfonylmethane (MSM) Improve Joint Health? Darrell Miller 10/6/11
Can Tea Tree Oil Reduce Scarring? Darrell Miller 9/16/11
Can Dietary Collagen Help the Skin and Joint Tissue? Darrell Miller 6/30/11
Fight Pain Improve Blood Sugar And Heart Health with OPC Pine Bark Extract Darrell Miller 6/7/11
How Does Holy Basil Extract Help with Pain Darrell Miller 5/19/11
Hyaluronic acid and your cells, eyes, and skin Darrell Miller 12/17/10
Are you experiencing Joint pain? Give Baxyl hyaluronic Acid liquid a try Darrell Miller 12/10/10
Ginger Root Darrell Miller 9/29/09
Boswellia Extract Darrell Miller 6/11/09
Cetyl Myristoleate Darrell Miller 5/8/08
Support Healthy Joint Function With Discount Vitamins Darrell Miller 11/22/07
Memory And Focus Darrell Miller 5/8/07
Learn about Bone Health! Darrell Miller 4/20/07
Glucosamine Sulfate and Chondroitin Sulfate Darrell Miller 3/28/07
Benefits - Supports joint function and tissue health* Darrell Miller 12/11/06
JOINT HEALTH Darrell Miller 12/22/05
Glucosamine & Chondroitin - JOINT HEALTH Darrell Miller 12/22/05
Nattokinase Fact Sheet Darrell Miller 12/8/05
- US Center for Disease Control, 2005 Darrell Miller 12/7/05
Celadrin and MSM Fact Sheet Darrell Miller 12/7/05
Utah's Inland Sea Minerals – Topical Application Darrell Miller 11/22/05
Research on SAMe.... Darrell Miller 10/26/05
Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of... Darrell Miller 7/27/05
Celadrin - Benefits Darrell Miller 7/27/05
SAMe - Supports Joint Comfort, Function and Mobility ... Darrell Miller 6/6/05
Joint Response and Ultra Joint Response Darrell Miller 6/2/05
Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort Darrell Miller 6/2/05
GlucosaMend™ Tissue/Joint Repair Complex Darrell Miller 6/2/05
Arcticpure EFA and EPA Fish Oil supplement ... Darrell Miller 5/31/05
Under-Reported (and Underappreciated) Cholesterol control. Darrell Miller 5/12/05
Celadrin® Complex with Glucosamine. Darrell Miller 5/12/05



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Andrographis
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Date: July 30, 2019 02:31 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Andrographis

Dear Friends,

I believe there’s an essential herb that everyone should be aware of, though not to many realize the powerful benefits of this near miracle botanical. This one nutrient has the ability to strengthen the immune system while also enhancing cardiovascular health, liver and kidney function, joint Mobility, and much more. Recent studies have shown this herb to be three times more effective than milk thistle for liver health. And while I know there’s no miracle supplement, that can prevent all disease, there are a growing number of studies to show that this herb can promote overall health and well-being in a tremendous way.

This herb, which I respect and hold in high regard, is andrographis. I believe it’s the next up-and-coming superstar in botanical medicine, and for good reason. I am not yet at liberty to give you the full details on a recent study, but I can tell you the results are impressive. The study involved treating three different groups of animals that had cancerous tumors. One group of animals was treated with curcumin, the second group was treated with french grape seed extract, and the third group was treated with andrographis. And while all three herbs were beneficial in this study, andrographis proved to be the most effective in reducing the cancerous tumors in the animals. I can’t wait to share the study details when it’s published.

It’s no wonder that andrographis has been used in natural medicine for years, due to its powerful antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, cancer-preventive, neuroprotective, and immune-stimulating properties. In fact, andrographis is the subject of over 800 studies in the National Institute of Health’s PubMed online database, with more to come!

You’ll learn how this amazing herb:

  • Strengthens immune defenses
  • Stops Viruses and resistant bacteria
  • Protects the liver
  • Prevents tumors and cell damage
  • Soothes digestive disorders
  • Prevents pain, inflammation, and arthritis symptoms
  • Supports energy and resilience
  • Protects heart and arteries

And the benefits don’t stop there. Please take the time to read more at TerryTalksNutrition.com

In Good health,

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6342)


Ten powerful anti-inflammatory herbs
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Date: August 30, 2018 03:38 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Ten powerful anti-inflammatory herbs





Ten powerful anti-inflammatory herbs

Inflammation in the body is a condition which makes itself known in various clear ways. These include swelling, pain and a mobility loss in the region affected. For an intervention to be effective against inflammation, it would need to address all three of these specific areas, generally by affecting the immune system. Fortunately, there are herbs which do indeed address these particular effects of inflammation. Research has shown that there are specific elements in each of the following herbs that are useful for ameliorating inflammation pain and swelling, and thereby improving motility. These herbs include ginger, spirulina, black pepper and curcumin.

Key Takeaways:

  • Inflammation makes itself known in the body by exhibiting the symptoms of swelling, pain and a loss of mobility to the region.
  • Specific ingredients in natural substances, like piperine, found in black pepper, and gingerol, found in ginger, are anti-inflammatory agents.
  • Other substances with anti-inflammatory action include the herb, curcumin, and the blue-green algae, spirulina.

"To be successful in the management of inflammation with herbs, every attempt has to be made to identify and use herbs that not only deal with inflammation per se, but also those herbs that can take care of individual symptoms."

Read more: https://guardian.ng/features/health/ten-powerful-anti-inflammatory-herbs/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5734)


Regular consumption of nuts may improve male fertility
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Date: July 05, 2018 05:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Regular consumption of nuts may improve male fertility





Regular consumption of nuts may improve male fertility

A new study has discovered that men that incorporate nuts into their diet can boost their male fertility. The study, which followed nearly 120 young men, found that those in the study group that regularly ate nuts that included walnuts, almonds, and hazelnuts experienced enhanced mobility and vitality as well as higher sperm counts. At the same time, the nut consumers were found to have lower levels of sperm DNA fragmentation, which can lead to infertility. More studies will be needed to make a solid connection between nuts and male fertility.

Key Takeaways:

  • Infertility is often due to sperm DNA fragmentation which is shown to be significantly helped by the consumption of nuts.
  • During this particular study, the participants consisted of 119 healthy men who followed a generally Americanized diet.
  • Human nutrition specialist Dr. Albert Salas-Huetos is who conducted this study regarding nuts and their association to fertility levels.

"The study participants who consistently consumed nuts showed notable improvements in the vitality, mobility, morphology, and the number of their sperm – factors that are all associated with male fertility."

Read more: https://www.earth.com/news/nuts-improve-male-fertility/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5656)


CBD Oil Benefits for Dogs
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Date: February 17, 2018 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD Oil Benefits for Dogs





The use of CBD oil as a supplement for humans has been growing in past years, as researchers discover new and promising benefits and regulatory restrictions are incrementally relaxed. But, did you know that this substance can have significant benefits for your dogs as well? Particularly, the use of CBD oil in dogs can help to improve cardiovascular health, as well as joint mobility. And, there are specific formulations which are aimed directly for use at our canine friends.

Key Takeaways:

  • Dogs have similar receptors for endocannabinoids like we do and can receive the same markers
  • CBD interacts similarly and doesn't have the psychoactive properties that can overwhelm a dog
  • The vet wing of the AMA has not officially said it is approved for dis 2 but studies are promising

"your canine family member can likely benefit from daily CBD oil supplements in much the same way you do."

Read more: https://www.medicalmarijuanainc.com/cbd-oil-benefits-dogs/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5531)


6 Natural Remedies To Cleanse Your Congested Colon
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Date: February 10, 2018 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 6 Natural Remedies To Cleanse Your Congested Colon





The colon is part of the digestive system whose function is to assimilate the nutrients of food, however, due to poor eating habits, this organ houses a large amount of toxic material that eventually wears it and generates health consequences; In this sense it is very important to consider healthy practices to improve the functioning and restore the health of this vital organ, such as drinking between 10 and 12 glasses of water and if it has a high level of alkalinity, excellent; the consumption of seeds of linanza provides a high content of fiber and omega3, the juice of lemon contributes with its detoxification and the consumption of plums helps its mobility. Finally these simple habits, can improve the health and life of your colon .

Key Takeaways:

  • The colon is one of the most important organs in the body, tasked with regulating digestion and absorbing nutrients.
  • However, many people do not take appropriate levels of take for their colon, allowing high level of toxins and waste to build up.
  • However, there are easy, natural steps that everyone can take to help improve colon health.

"It just so happens that one of the most effective ways to cleanse and detoxify your colon is also one of the easiest: drink more water!"

Read more: https://www.thealternativedaily.com/6-natural-remedies-cleanse-congested-colon/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5525)


Olive Oil With Lemon In The Morning Can Do Wonders To Your Body
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Date: September 21, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Olive Oil With Lemon In The Morning Can Do Wonders To Your Body





Olive oil along with a lemon in the morning can do a lot of good for your body. Mixing them together can work wonders for your health. It helps to combat constipation. It gets rid of the toxins in your body. It protects the heart as well. Olive oil contains fatty acids that is good for the blood. Vitamin C is in lemon and is great for you too. Using lemon and olive oil will also help with joint pain.

https://www.youtube.com/watch?v=NQzpUuUgXT0&rel=0

Key Takeaways:

  • Mixing olive oil and lemon can produce many health benefits for both adults and children.
  • Olive oil and lemon mixed together can reduce inflammation and improve joint health.
  • He mixture of olive oil and lemon is beneficial to GI health and can improve Mobility and digestion.

"It effectively helps us get rid of those things that our body naturally wants to get rid of."

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5268)


Treat Your Arthritis Problems With Gelatin Amazing!!
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Date: June 04, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Treat Your Arthritis Problems With Gelatin Amazing!!





People who suffer with arthritis should consider the alternative and natural remedy of Gelatin. Gelatin is mostly know as an ingredient in candies and milk, but if used a teaspoon twice a day can considerably lower your pain level associated with arthritis. Gelatin has proteins made from animal cartilage bones and tendons. Most of the time we have gelatin in foods we would have never known. just by having this small amount 2 times a day can change the pain associated with arthritis in 4 to 6 weeks!

https://www.youtube.com/watch?v=zum4zToUk4Q&rel=0

Key Takeaways:

  • With advancing age we lose collagen, which affects joint flexibility and Mobility.
  • Medicines that alleviate the general discomfort of arthritic conditions can also produce long-term side effects.
  • Gelatin is created by the hydrolysis of collagen, which comes to us from the bones, tendons and cartilage of animals.

"Although there are medicines that reduce pain, these do not disappear forever."

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4765)


Tips for Keeping Your Joints in Top Shape
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Date: May 14, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Tips for Keeping Your Joints in Top Shape





Many people suffer from joint pain due to lifestyle, nutrition, and lack of exercise among others. The discomfort can cause stress. Movement helps to increase mobility as well as exercise. Running, however, is not recommended as it can cause ligament damage.Weight loss can also help alleviate joint pain. Added more omega-3 to ones diet can help prevent bones from breaking down thus relieve joint pain.Maintaining a correct posture is good for all joints and can ease pain from the neck down. Stretching is also a great way to keep joints healthy.

Key Takeaways:

  • Get regular exercise so that you are able to continue with a lot of mobility
  • Make sure that you stay hydrated to continue with peak movement in all your joints
  • Do not lift things that are to heavy or over extend your movements

"If you have joint pain and you know that you’re overweight, it’s time to take steps to lose the extra weight."

Read more: http://drprem.com/health/tips-for-keeping-your-joints-in-top-shape

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4611)


These raised bed gardening tricks beat traditional gardening every time
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Date: March 29, 2017 11:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: These raised bed gardening tricks beat traditional gardening every time





Raised bed gardening methods involves preparing crops in a variety of ways using elevated garden beds. Benefits of raised garden beds include better drainage as well as better retention of moist soil. This makes raised beds particularly effective in rainy environments. In addition to better drainage, raised beds also provide better aeration. Raised beds allow effective use of the loose soil such as air circulation and nitrogen being converted to useful minerals. Other benefits include better weed control, pest control, and improved mobility.

Read more: These raised bed gardening tricks beat traditional gardening every time

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4316)


Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis
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Date: March 22, 2017 11:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eating anti-inflammatory foods may reduce symptoms of rheumatoid arthritis





As it happens your diet may have a significant impact upon the likelihood of Rheumatoid arthritis (RA) eating away at your joints as you age. 70% of white blood cells occupy the human intestinal tract - as RA is an auto-immune disease that turns the body's natural defenses against itself the link is worthy of further study. Several recent studies have made the connection between good diet (olive oil rather than butter) and RA incidence as well as severity and progression of the debilitating disease. The benefits of a good diet contrast with the current medical treatment prognosis for RA which actually weakens the immune system overall, opening the body up to any of a number of potential risk factors which eating right will strengthen the body's ability to resist.

RA is a life threatening disease which kills about 40,000 Americans annually and has a three to one preference to affect the female gender. A quarter of RA patients reported that a few specific dietary changes made noticeable impact, namely increasing blueberry and spinach consumption and reducing processed sugars.

Key Takeaways:

  • You are what you eat can also be phrased as you are as healthy as the food you eat.
  • Traditional rheumatoid arthritis treatment aims at treating the symptoms, especially maintaining and regaining mobility, but it does nothing to treat the actual illness.
  • A study showed following a Mediterranean diet rich in monounsaturated fats like olive oil improves RA symptoms.

"Recent medical research has suggested a strong link between the autoimmune illness rheumatoid arthritis and our food choices."

Read more: http://www.dailyherald.com/article/20170318/entlife/170318970/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4260)


How to strengthen your bones
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Date: December 10, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to strengthen your bones





The vast majority of those affected are over 50, and mostly women - one in two women, and one in five men over the age of 50 will break a bone as a result of osteoporosis, according to the National Osteoporosis Society, with the wrists, hips, and spine most commonly affected. Stress exerts its adverse effects on bone density, mainly via the action of cortisol, one of the major stress hormones, says Max Tuck, author of Love Your Bones: The Essential Guide To Ending Osteoporosis And Building A Healthy Skeleton.

Key Takeaways:

  • It's easy to dismiss osteoporosis as an inevitable part of growing old - but understanding the causes, and how to manage the condition, can make a big difference.
  • Severe osteoporosis can be very problematic due to the increased risk of fractures - which can have a knock-on effect, including pain and Mobility difficulties.
  • The key reason for this is menopause, when a woman's ovaries stop producing eggs, and eventually periods stop.

"It's believed that more than three million people in the UK are currently living with osteoporosis, associated with weakened, fragile bones."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.heraldscotland.com/life_style/14927262.How_to_strengthen_your_bones/&ct=ga&cd=CAIyGmU0N2NhMzY3ZTc4ODMzY2U6Y29tOmVuOlVT&usg=AFQjCNG3NBdkUanmESxcSVU75-3EfLEHXQ

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3611)


Maca Root And Your Health
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Date: September 28, 2016 07:50 AM
Author: Darrell Miller
Subject: Maca Root And Your Health

Maca, (Lepidium meyenii) also Peruvian herb is a biennial herb indigenous to Andes, Peru. It’s also grown in Brazil and Bolivia. It’s cultivated for its fleshy hypocotyl and tap root which is a root vegetable and a medicinal herb.

Brief history

For over 2000 years, Maca root has been used by the ancient Incan culture for medicinal uses. They highly revered the plant for its legendary ability to offer mental clarity and energy as well as enhancing sex drive.

Today, Maca root is medicinal and health benefits such as:

  •  Hormonal balance to improve menopause and PMS symptoms in women as well as mood and fertility
  •  Improving sperm production, volume, and Mobility in men
  •  Reduces enlarged prostates
  •  It’s used as an aphrodisiac to improve sex drive
  •  Increasing bone density especially in women

Maca root and Energy improvement

Maca contains vitamins, fatty acids, proteins, and minerals. These are elements to naturally support energy supporting as well as aid in injury recovery. Those who have used maca root in powder form have testified that it makes them awake, driven and energized. They even prefer it over caffeine as it doesn’t give jitters.

Clinical studies have revealed that maca is useful in maintaining positive energy levels and reducing anxiety and depression. It’s also important in regulating the hypothalamus, which improves the functioning of pituitary glands and thus balancing focus and energy. Researchers believe this is enhanced by balancing blood sugar levels.

Maca root holds many health benefits, if you are over the age of 50, you should be taking maca root daily to help balance hormones and feel better.


Reference URLs

https://draxe.com/top-5-maca-root-benefits-and-nutrition/

//www.globalhealingcenter.com/natural-health/7-benefits-of-maca-root-for-women/

//www.webmd.com/sex-relationships/guide/the-truth-about-maca

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3316)


Boswellia - The Anti-Inflammatory Herb
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Date: July 23, 2015 03:07 AM
Author: Darrell Miller
Subject: Boswellia - The Anti-Inflammatory Herb

Boswellia is some times referred to as Indian frankincense or boswellin.  It comes from a tree known as boswellia serrata that is found to grow in the dry areas of India.  Boswellia is said to have 55% of Boswellic acid.  For centuries, many Indian healers have always taken the advantage of the anti-inflammation property of this tree.  The bark's gummy resin contains anti-inflammation content in higher percentages - its known as salai guggal.

Boswellia

In the modern world, preparations are done from a purified extract of the resin and normally packed in cream or pills which are then used mainly to reduce inflammation; rheumatoid or osteoarthritis arthritis.  Unlike nonsteroidal anti-inflammatory drugs, like ibuprofen, which is one of the accepted treatments for joint inflammation, - boswellia according to research does not show signs of stomach irritation.  It's also sometimes effective when it comes to back pains and other chronic related intestinal disorders.

Its health benefits, according to research by scientists, has been outlined that this herb has specific and very active anti-inflammation ingredients.  These ingredients are commonly known as boswellic acids.  In the field of animal studies, boswellic acids have been proven to reduce inflammation.  They improve rapidly the blood flow to the joints. They also do block those chemical reactions that always sets the stage for inflammation that cause chronic intestinal disorders.  Boswellia maybe taken internally or even applied topically to the affected joints to help relieve inflammation that is associated with joint disorders.  These always increase joint Mobility and lessen the morning stiffness.

In a study that was conducted involving 175 patients suffering rheumatic disorders such as rheumatoid arthritis, exactly 122 participants were found to experience reduced inflammation and stiffness after using boswellia for two to four weeks.  Boswellia's inflammatory component helps reduce stiffness and aching, especially when associated with the low back pains.  Though a lot of researches done shows that boswellia is effective when taken orally, creams also appear to be soothing all together.

Boswellia also seems to reduce the inflammation related with Crohn's and ulcerative colitis disease, of which both are painful intestinal disorders. It's said to be able to accomplish this without actually the risk of gut irritation which is mainly associated with lots of convectional pain relievers.

In the ?year 1997, a study was conducted involving ulcerative colitis victims, 82% those who took this boswellia extract like 3 times in a day, they experienced total and complete remission of this disease.


Read More

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Can Celadrin Help Joint Pain?
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Date: March 05, 2014 08:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Celadrin Help Joint Pain?

Celadrin

In clinical studies, Celadrin cream application has been demonstrated to lessen joint torment in less than 30 minutes. This quite viable, all-common mitigating medication holds a protected mix of specific greasy acids and some menthol's to help reduce torment in the joints, advertise joint flexibility and grease and to help smooth sore muscles.

How can it function?

A long time involving usage in addition to strenuous action can certainly reduce the Mobility of your joint parts in addition to deterioration your water that ones your joint parts via pain, ultimately producing osteoarthritis. Celadrin gives remedy in addition to rejuvenation of those joint parts. The item functions by lubricating your mobile walls, so improving your extra padding power involving joint parts in addition to bones. Fat have also been proven to avoid your routine involving redness, making an effort to relieve pain within the joint parts in addition to muscular tissues. When you suffer from muscle mass in addition to joint, Celadrin ointment affords the relief you have to make it through your worktime. Analyzed from prime educational facilities in addition to major medical stores, Celadrin ointment gives relief in order to aching muscular tissues in addition to joint parts.

It provides lubrication in addition to works just like a "cushion" among joint parts in addition to cartilage. Rigid joint parts in addition to pain are generally as a result of bad lubrication. Celadrin Product gives remedy in order to fatigued, aching muscular tissues in addition to joint parts. The majority of people think outcomes inside a half-hour.

Scientifically Efficient Joint pain Pain relief

The results involving human being specialized medical trial offers assist the effectiveness of Celadrin ointment. In a double-blind placebo-controlled trial run released within the Journal involving Rheumatology, forty five participants along with uncomfortable knee joint parts - ingested both Celadrin Mutual Proper care Pain relief or even a placebo ointment to put on topically double every day intended for 1 month. Members have been evaluated on several orthopedic procedures involving development. At the conclusion in the examine, your analysts known that the Celadrin had been a simple yet effective therapy intended for enhancing knee Mobility, chance to ascend/descend stairways, chance to surge via seated, go in addition to have a seat, in addition to unilateral sense of balance. No changes have been welcomed in your placebo class. Another examine involving 28 people who have arthritis in the knee additionally revealed major improvements throughout knee function, range of motion in addition to pain decrease in a matter of a single week involving utilizing Celadrin ointment.



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How Do You Reduce Arthritis Naturally?
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Date: December 05, 2013 02:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Do You Reduce Arthritis Naturally?

What is Arthritisginger

Arthritis is a complex family of disorders that affect the musculoskeletal system of humans. It manifests in 100 different diseases or conditions and it affect two-thirds of people who are under the age of 65. It affects both the old and the young. The common forms of arthritis are Osteoarthritis (OA), Rheumatoid Arthritis (RA) and Juvenile Arthritis (JA). Exercise remains a valuable tool in the fight against the disease, especially when it’s combined with the appropriate diet and diet supplements. Other than the preventive tactics of avoiding joint injury, arthritis victims can still find help naturally by using glucosamine and hyaluronic acid in foods and plant extracts.

Symptoms of Arthritis

The main symptoms of the disease include difficulty in moving joints as well as swollen joints that may lead to severe problems when movement is forced. The disease also causes eye, skin and other organ disorders but not on all patients.

Glucosamine

Glucosamine plays a key role in forming connective tissues. It helps people cope with discomfort and Mobility problems that arise out of stiff joints. It works by fortifying the protective cushioning between bones. It does not directly improve the bone function, but it leads to better coping with old age and thus delays the onset of joint diseases like arthritis.

Benefits of Glucosamine

Glucosamine works closely with hyaluronic acid to rebuild and support tissues in joints. The hyaluronic acid hydrates and lubricates the joint tissues because of its excellent water trapping and retaining properties. This helps to enhance the body’s ability to absorb shock.

Natural way to deal with Arthritis

A natural way to deal with this disease is to consume foods and extracts that are rich in anti-inflammatory and antioxidant activity. Some of these foods include methylsulfonylmethane, ginger, turmeric and boswellia. Unlike over the counter prescriptions, boswellia is able to impede inflammation and relieve discomfort by reducing the swelling of joints for those who have arthritis. The other foods like ginger and turmeric are also helpful because they have no serious side effects and they work just as well as boswellia.

Referencess:

  1. //www.medicalnewstoday.com/articles/7621.php//www.futurebiotics.com/health-topics/14//www.arthritis.org/conditions-treatments/understanding-arthritis/

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Boswellia Can Help you to Reduce all type of Inflammation Pain
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Date: November 06, 2013 09:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boswellia Can Help you to Reduce all type of Inflammation Pain

What is Boswellia

boswellia plant

There are so many natural medicines that can help you to fight against pain and boswellia is one of them. This is one of those herbs that are being used by various cultures as an effective pain killer since a long time. Other than this, this herb is also known to the world as Indian Frankincense and it can help you in inflammation as well as circulation of joints and stiffness of muscles.

Benefits of Boswellia

Talking about the effect of boswellia on pain, many modern researches also proved that it works great as an anti inflammatory medicine. These researches proved that boswellia contain a triterpenoids that is commonly known as boswellic acids and this is responsible for relief in pain. These researches also proved that t boswellic acids are highly beneficial in pain and it has very few toxic or harmful content compared to any other popular anti inflammatory product.

Effect of Boswellia

Other than this, researchers did some blind study in which they included 30 people that had problem of osteoarthritis of knee and researched compared the effect of boswellia against placebo that is another good anti inflammatory product. In this study participants either received boswellia as an anti inflammatory product or they got placebo for initial 8 weeks. After that researchers switched the medicines for next 8 weeks and patients found that they received much better result in pain with boswellia compared placebo. Additionally they also found great improvement in knee Mobility, walking and reduction of knee pain while consuming boswellia.

On the basis of these researches and its history we can easily say that boswellia can easily help you to fight against any kind of pain it gives great result in case of muscles stiffness or joint pain. Other than this, its anti inflammatory property can help you in variety of other pain including sprain, fatigue or hurting.

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Can The Consumption of Collagen Help Hair, Skin, Nails, And Joints?
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Date: May 30, 2013 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can The Consumption of Collagen Help Hair, Skin, Nails, And Joints?

Collagen is produced naturally by the body. It's a protein contained in connective tissues in the body. The benefits of collagen supplements are the most amazing fad on the market for health and beauty industry recently.

About 25% of proteins contained in our bodies are collagens. It is the second greatest substance in the body following water. Its production reduces as people get older. However, supplements are available in the market and help restore the quantity of collagen in the body. Collagen supplements are available in different forms such as gelatin and elastin. Gelatin has been used for a long time to strengthen nails and hair.

Collagen needs to be taken with water, 2 hours after taking a meal. It needs to pass through the stomach into the intestines and not get digested. In case it is broken down then it becomes ineffective so it is wise to take collagen on an empty stomach.

Below are some benefits of collagen;

Collagen for skin

It works to eliminate signs of old age by making skin firm, flexible and young because of the fibrous and steady structure of the substance. Several plastic surgeons use the substance to provide their customers a youthful look. Collagen is introduced directly to the skin on the parts with depressions formed by wrinkles. It makes the wrinkles less visible. The injection might last for about 6 months before you undergo another procedure to eliminate wrinkles. The time used to complete this procedure depends on the extent of wrinkles. Reduce occurrence of cellulite and works to restore the fibers that make cellulite to appear on skin. It is also used for artificial skin treatment for burn patients. Collagen applied in this process is usually acquired from bovine or equine to restore damaged skin as a result of burns.

Joints

Collagen supplements help reduce rheumatoid arthritis signs such as joint inflammation and lack of Mobility. This might be because of collagen anti-inflammatory components and impacts on the body's immune system. Osteoarthritis and rheumatoid patients use collagen supplements to treat joints. It offers a supportive structure for many body tissues, for instance, muscles or bones. It helps to rebuild cartilage material found in joints. Collagen reduces pain due to these conditions as well.

Nails

Collagen helps to strengthen nails and help to get rid of the white spots. Frequent use will help the nail-bed to maintain a healthy color.

Hair It's a key component in hair growth since it kills free radicals that can affect your hair texture, growth and thickness. Applying oils with collagen on the hair shaft could enhance hair growth. Taking collagen capsules reinforce hair and increase the thickness of a person's hair, providing your hair with an generally fuller look.

The suggested quantity for hair regrowth and thickness for aesthetic purposes is 4-6g. It also helps to decrease the appearance of grey hair by improving structure and health of hair follicle. Apply collagen creams directly on the scalp to make grey hair look darker and less dried out. Collagen is very efficient in treating dry brittle hair. It is useful in restoring and reversing split ends and also enhancing moisture levels in the hair.

If you are not currently taking collagen, whats stopping you?

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The Amazing Health Benefits of Curcumin
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Date: April 19, 2012 07:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Amazing Health Benefits of Curcumin

Curcumin

Have you heard of curcumin? Curcumin is a popular spice that originated in Eastern culture. This spice is popular because it offers a lot of health benefits to people. For those individuals who are interested to achieve optimal health and want to live a longer life, it would be best to ad curcumin in their daily diets. This spice can definitely affect the overall health of individuals.

What is curcumin?

Curcumin is not just an actual spice, but it is one of the ingredients of Tumeric, which is considered a famous Indian spice. Curcumin is commonly used in making curries with a strong taste that are being appreciated in the West. However, this ingredient is consumed by many people because of the health benefits it could bring. Curcumin is very in demand in India, Middle East and Asian countries because they use curcumin as a medicine.

There are various health benefits of curcumin. If you want to take advantage of these benefits, it is important that you be aware of these health benefits:

Benefits

• Helps treat certain illnesses- According to research and studies, it has been shown that curcumin can effectively treat and prevent particular ailments such as brain problems and cancer. Individuals suffering from Alzheimer's disease can definitely overcome their condition with regular consumption of curcumin.

An effective body pain reliever- A lot of individuals, most especially the senior citizens are always experiencing body pains because of weak bones. According to a recent study, curcumin has been believed to relive pain and improve Mobility for sufferers with osteoarthritis and other body pains. Curcumin contains anti-inflammatory properties that help alleviate body aches.

Positive effects on brain health- Another awesome benefit if curcumin is providing positive effects on brain health. According to reports, even just occasional ingestion of curcumin can improve brain power. It is necessary to have a healthy and powerful brain so that it is easier to think clearly all the time. It also effectively reduces the levels of toxic metals in the brain.

Helps avoid premature aging- Curcumin is packed with antioxidants, which are responsible in preventing the occurrence of premature aging. Premature aging is a very common condition, most especially to people with an unhealthy lifestyle. It would be best to stop all your filthy habits and add curcumin in your regular diet to achieve a healthy body and younger looking skin.

These are some of the amazing health benefits of curcumin. If you want to achieve a healthy body and mind, this healthy supplement is the excellent supplement to utilize. There is no recommended dose for curcumin. Studies have utilized doses between 100 mg to 8000 mg without experiencing any over dosage side effects. In fact, individuals can consume up to 12,000 mg per day.

Curamin can either be consumed as a supplement, or it can be added in certain food or meals. Basically, people in India would add this spice to their every dish so that they could attain superior health. You can also add curcumin when you are cooking, but if you have no time to cook, nutritional supplements can be the perfect alternative.

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What Are the Health Benefits Of Collagen Tablets?
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Date: April 10, 2012 06:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are the Health Benefits Of Collagen Tablets?

Collagen

Collagen is one of the most important components involved in the formation of your body's ligaments, tendons, cartilage and muscles. As you get older, your body's ability to manufacture the required amount of collagen becomes lesser. Collagen tablets covers up for it by helping maintain the repair process. These tablets also have different benefits that you should consider and these benefits re given below:

Improves blood circulation: this happens because collagen tablets improve the elasticity of blood vessels, making them stronger and this improved blood flow.

It enhances healing of injuries: when our bodies cannot provide sufficient nutrients required to repair the body tissues, these tablets compensate for the loss. The structure of the bones, cartilages and other parts are also strengthened by this. It encourages the regeneration of muscle mass making recovery after sport related injuries faster.

Keep Arthritis pains at bay: the disease associated with joint inflammation and painful Mobility around the areas is referred to as Arthritis. Collagen tablets work at reducing this pain making movement around the joints more comfortable.

Reduces the appearance of cellulite: when fatty tissues find way to the upper layers of the skin, dimples often occur. This is referred to as Cellulite. These tablets reduce this occurrence by rebuilding the destroyed fibres that allow cellulite to appear.

Helps in reducing wrinkles: when our bodies no longer produce collagen, certain lines form on the places that move most, like our foreheads and joints. This is referred to as wrinkles. The tablets work by increasing the suppleness of the skin.

Improves the hair structure: these tablets fight free radicals which often affect the texture and growth of our hair. Replacing this component in the shaft of your hair will give your hair better appearance.

It is advisable to start taking these tablets from as early as thirty years as this will prevent the onset of the above conditions. It also makes your skin look younger by preventing wrinkles. One should use these tablets because its absorption occurs naturally through the blood stream, making it possible for your body to decide its destination. If you are an athlete, this is just the thing for you as it facilitates the healing of wounds making it possible for you to be back on the field within a short time. The tablets can help soften your stiff joints if you find it hard to exercise because of that. If acne is your problem, then you won't have to worry, because this drug works with your skin's keratin to produce the best results ever. It is also said to have an effect in weight loss.

One thing that you should note is that collagen tablet works best on an empty stomach, so for the best results, take it early in the morning or before meals. These tablets are cheap and easy to find. They contribute greatly to your health and overall appearance. Now that you know, take that short trip to the nearest chemist and take control of your future life! Collagen tablets are a good way to start.

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How Does Methylsulfonylmethane (MSM) Improve Joint Health?
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Date: October 06, 2011 01:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Methylsulfonylmethane (MSM) Improve Joint Health?

As we all know, our health is truly fragile thus, there is a very big need for all of us to take good care of our health by engaging in different ways and means to strengthen it. However, because of the kind of world that we live in right know, there are times when it is very difficult to live healthy because of all the temptations that are detrimental to our health. Fortunately, due to the constant innovations and advancement in the field of medicine, various supplements are already identified that are proven to be effectual in helping you maintain optimum health. One of these great supplements that are available today is methylsulfonylmethane.

Methylsulfonylmethane or more commonly known for its abbreviation MSM is a very vital and effectual supplement. Several studies have been conducted and would prove that MSM cures wide array of medical conditions such as gastrointestinal disorders, joint problems, and allergic reactions. The supplement is also used to improve circulation, cell vitality, as well as enhance skin elasticity and smoothness. MSM also have active components that could lessen post athletic activity fatigue.

MSM performs two very significant processes in the human body. A portion of the excess MSM that you consumed will be flushed out from your body in about 12 hours. And along with the excretion of MSM are the detrimental toxins that are injurious to your health. It is also part in the cellular makeup of the cell walls of all the new cells that is manufactured by your body because as we all know, our body is constantly producing new cells to replace cells that are already old. During the process of cell creation MSM plays a vital role to make the production successful. MSM is incorporated in the polypeptide bonds that make up the cell walls. As a result, cell walls become more permeable therefore, nutrients and vitamins can easily pass through. Without the presence of MSM, cells would become impermeable thus the person would experience nutrient deficiency.

Aside from improving overall health, MSM is also proven to be effectual in maintaining joint Mobility. Various clinical studies would also validate and prove that pain and inflammation brought about by arthritis, gout, and other medical conditions that involve the joints showed significant improvement after taking MSM supplement. The reason behind its efficacy is because of the sulfur enhancement of the sodium-potassium pump which in turn enhances fluid flow and removal of cell toxins therefore could cure inflammation and pain.

Because of all these good things for your health that you could get from MSM, it is really a supplement that you need to take. And if you are one of the many who are suffering with joint pains and inflammation for quite some time now, then it would be suitable enough to give MSM a try and allow yourself to embrace the wonderful changes in your body and health.

Grab some MSM for yourself and feel the difference it can make in your life!

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Can Tea Tree Oil Reduce Scarring?
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Date: September 16, 2011 03:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Tea Tree Oil Reduce Scarring?

Overview

Scarring can be traumatic for any person and yet it may be a source of pride for others, in fact many native cultures in the world that is still left untouched by the modern world still has scarring as part of decorating their bodies. However we also need to look at it in a different view, it is a fact of life that we do not live in a native world, we need to adhere to common beliefs in terms of what beauty is and let’s face it, being full of scars is not something that many people look for and deem as beautiful.

How does it happen?

The formation of scars is a natural process. It simply is our body healing itself after injury. The main difference though is that when the skin is the part of the body that is injured it leaves a mark that we can see and I say that because like all healing processes in the body their always is a small mark left and the problem never really gets completely repaired unless the injury happens while you are very young or if you have amazing regenerative gifts. There are a lot of factors that could influence scars and of course depth and size of the injury are the ones that play a major role in shaping the scars characteristics.

Types of Scars

First and most common are Keloid scars. This is a result of a very aggressive healing process by the body and in some cases it even can affect Mobility as it extends beyond the normal wound or injury. Second would be Hypertrophic scars. These types of scars are a little similar to keloid but the main difference is that it does not extend out of the injury zone but in terms of look and texture it is very similar to keloid. The third are contracture scars. This is commonly caused by the burning of the skin. It also has the ability to impair your Mobility as this has a characteristic of going deeper into your muscles and nerves to impede its functionality. Lastly you have the scars that result from acne and which is appropriately named as acne scars.

Tea Tree Oil and Scars

This oil has been known to have wondrous effects to the health with even just one drop. Studies have shown that the use of Tea Tree Oil or also known as meleleuca alternifolia on scars is one of the most effective ways to aid in the treatment of scars. Its strong cell regenerative properties are what makes tea tree oil important and potent in healing scars. It also could help in preventing other skin problems and acne.

Another reason why it is so effective is it has a natural antiseptic effect for skin infections and problems and it is able to penetrate the epidermis to do its healing from within which adds to its potency. Plus, the best thing about it is that, it is mild on the skin, it does all this without any side effects that other skin treatments has like drying the skin or causing minor irritations.

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Can Dietary Collagen Help the Skin and Joint Tissue?
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Date: June 30, 2011 10:45 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Dietary Collagen Help the Skin and Joint Tissue?

Collagen and Your Health

Collagen is the most common form of protein in humans and other mammals. It is a major constituent of the extracellular matrix that provides structural support to animal cells from the outside. It displays great tensile properties, which is responsible for the strength and elasticity of the skin. Since it is a component of fibrous tissue, it is also found in ligaments and cartilages that make up joint tissue.

Dietary collagen has long been postulated to contribute to the biochemical composition of cells present in the skin and joints. Proponents of collagen supplements believe that dietary collagen is assimilated into the extracellular matrix and fibrous tissue. The scientific community has been doubtful about the efficacy of topical applications of collagen, but oral supplements have been promising in clinical trials.

Molecular collagen is composed of polymers of amino acids linked by peptide bands, which are too big at the cellular level to get absorbed through skin. On the other hand, intestinal absorption of dietary collagen remains a matter of controversy. That being said, nutraceutical companies have developed formulations of supplements that facilitate the best possible absorption rates and better bioavailability.

Tough bundles of collagen fibers comprise several polypeptide chains of fibrous structural proteins. All fibrous tissues have cells and extracellular matrix in between. High concentrations of collagen found in cartilages, ligaments, tendons, fascia, and even bones give these fibrous tissues tensile strength, the reason why the joints are capable of bearing a certain level of longitudinal stress without tearing apart.

Structural proteins make up the outer layer of the human skin and its appendages, such as the scalp, hair, and nails. The most important of these proteins are collagen, keratin, and elastin. Collagen fibers are responsible for the tensile properties of the skin. Keratin provides strength whereas elastin exerts an elastic effect. Collagen fibers affect the process of healing and its degradation leads to wrinkles.

Oral route of administration is believed to produce the health benefits linked to dietary collagen. While researchers have ruled out the health claims tied to collagen creams and lotions, they have reported encouraging results about dietary collagen. In fact, collagen supplements utilized in the management of rheumatoid arthritis and treatment of skin disorders have produced significantly positive outcomes.

One clinical trial that involved more than 200 participants diagnosed with rheumatoid arthritis point to the medicinal potential of collagen as an adjunct treatment for rheumatism and osteoarthritis. There was a noticeable decrease in joint pain, morning stiffness, and restrained Mobility, which were noted as statistically significant. For this reason, supplementation of collagen has attracted more research.

Dietary collagen is now becoming increasingly visible in the nutraceutical industry in that sales have increased in the past few years. It has become the subject of numerous studies well underway, and as such developments in collagen supplementation are expected to produce formulations specialized for higher bioavailability. The good news is dietary collagen has not been linked to any adverse effects.

Get some collagen today and feel the difference it can make in your diet!

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Fight Pain Improve Blood Sugar And Heart Health with OPC Pine Bark Extract
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Date: June 07, 2011 11:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Pain Improve Blood Sugar And Heart Health with OPC Pine Bark Extract

How Does OPC Pine Bark Boost Your Health?

OPC pine bark has become increasingly popular in the supplement industry due to obvious reasons. It is one of the best antioxidant formulas available today. There has been so much research involved in its development, and the studies that followed have published largely positive results. In the past few years it has received a lot of good press, which has significantly contributed to its commercial success.

OPC stands for oligomeric proanthocyanidin, a class of flavonoids. OPC has been in use as a nutritional supplement since the 1980s. To this day, it remains an important source of polyphenolic antioxidants. Moreover, it has been linked to a diverse variety of health benefits, and laboratory studies concerning its effects on human health are well publicized. Pine bark extracts are one of its best known sources.

Promotes Heart Health

OPC pine bark has long been associated with heart health. For one, it has shown to help lower lipid levels in the blood, including cholesterol, triglycerides, and lipoproteins. It interferes with the productions of bad cholesterol into the blood and protects the blood vessels from lipid peroxidation.

In addition, it facilitates normal flow of blood and combats chronic venous insufficiency. It contributes to the upkeep of blood vessel walls and keeps the veins and arteries in prime working condition. By so doing, it promotes proper circulation to the deepest reaches of the body and back to the heart.

Improves Kidney Function

OPC pine bark is particularly good for the kidney as it appears to improve renal function, especially in the context of metabolic syndrome. Central obesity, insulin resistance, diabetes mellitus, and high blood pressure are all symptoms of metabolic syndrome, which takes its toll on the kidneys.

Kidney problems have been observed in people with elevated levels of albumin in the urine. When filters of the kidney are damaged, proteins from the blood such as albumin leak into the urine. OPC pine bark restores health to the capillaries in the kidneys that filters waste materials from the blood.

Counteracts Pain Chemicals

Sufferers of joint pain are likely to benefit from OPC pine bark. Joint pain is often tied to osteoarthritis, the most common form arthritis. It is often accompanied by stiffness and reduced Mobility. OPC pine bark has been used as a therapeutic treatment for osteoarthritis and other causes of joint pain.

There is good evidence that OPC pine bark is effective in counteracting pain chemicals and relieving inflammatory pain. In several randomized, double blind, placebo controlled studies, regular intake of OPC improved joint pain and stiffness, reduced reliance on analgesics, enhanced physical function.

Prevents Oxidative Stress

OPC pine bark is free radical scavenger, first and foremost. It is arguably the most researched plant polyphenol largely owing to its potent antioxidant capacity. As an antioxidant, it prevents radical damage from progressing to oxidative stress and promotes cellular longevity.

OPC Pine bark may also help manage blood sugar. What is stopping you from taking OPC pine back daily?

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How Does Holy Basil Extract Help with Pain
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Date: May 19, 2011 01:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Holy Basil Extract Help with Pain

Holy Basil And Pain Management.

Holy basil extract is an herbal remedy that originated from India. It is best known as an adaptogen, and as such has become an increasingly popular herbal supplement in the past few years. It is effective in the management of stress, and anecdotal evidence is very positive. More importantly, recent studies have compared its analgesic properties to commonly used pain relievers in the market.

Pain Perception

Many different factors are involved in the perception of pain, but most painful conditions are tied to the process of inflammation. Pain is in fact a mechanism of the human body in response to situations that are potentially harmful or even life-threatening. For example, signals are sent to the brain from the body part exposed to extreme temperatures, allowing us to move away from the harmful stimulus.

Pain is of course an undesirable condition, though it is helpful in certain situations. The thought of pain alone brings about disagreeable feelings, such as fear. No wonder people are always seeking for remedies for physical pain, which can be caused by open wounds or physical trauma. More often than not, it is linked to routine activities, such as bad sleeping positions and sitting for long periods of time.

Common Factors

Modern lifestyle renders the human body more susceptible to pain, brought on by injuries and wounds as well as physical inactivity. There are countless working conditions that doctors and medical professionals have pointed out to be real occupational hazards. We often do not care so much about the way we work because the repercussions are not immediately felt, not while we are young. Two major factors lead to chronic pain later in life: wear and tear of tissues and limited physical exertion.

We become increasingly sensitive to pain as we age. We keep a wrong position during sleep sometimes, and the next morning we feel all sorts of muscle pain, such as neck pain. Similar pains take place every time we lean into our computer at work. In general, these kinds of pain are due to poor posture, which can easily be remedied. However, this can take a turn for the worse in the next couple of years as we continually subject our body to muscle strain and physical imMobility.

Inflammatory Mediators

This is when natural remedies can help us. Holy basil has an age-old association with the relief of pain due to muscle strain. The chemical compounds that occur naturally in the plant species Ocimum tenuiflorum have been discovered to interact with mediators of inflammation. Researchers have learned that holy basil extracts are not only relieves pain but also contributes to holistic health.

More importantly, holy basil extracts appear to inhibit an enzyme called COX-2, which facilitates the biosynthesis of pain chemicals. Its role is to get our attention and tell us that there is something wrong with our body. This enzyme is responsible for the sensitizing arthritic joints to pain. It is also implicated in severe headaches, migraine attacks, muscle cramps, and related symptoms.

If you experience chronic pain, give holy basil a try!

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Hyaluronic acid and your cells, eyes, and skin
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Date: December 17, 2010 10:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hyaluronic acid and your cells, eyes, and skin

Hyaluronic Acid

Discovered in 1934, hyaluronic acid can be found anywhere there is the need for connective tissue in your body. Your joints, your eyes and your heart all contain hyaluronic acid, and a shortage can lead to a wide range of bodily defects, including the appearance of accelerated aging. It is a glycosaminoglycan, a form of polysaccharide that is not only found in connective tissue and epithelial and neural cells, but is also important in the growth and renewal of body cells.

baxylWe shall discuss here how hyaluronic acid affects specific areas of your body, and what the effect of a deficiency would mean, but also keeping in mind that an excess of this polysaccharide can also have a serious impact on your health although it offers few side effects worth noting.

Hyaluronic Acid and Your Joints

The highest concentrations of hyaluronic acid (HA) in your body is found in the synovial fluid, the fluid lubricating contained in your joints, and it is also plays an important role in maintaining the function of cartilage in keeping your joints flexible and well cushioned. It is chemically a glycosaminoglycan that is formed from glucosamine and glucuronic acid. Its production is boosted by chondroitin, which is why glucosamine and chondroitin are commonly used supplements for the treatment of arthritis.

Specifically, HA joins with collagen and elastin to produce cartilage, and also increases the supply of synovial fluid that maintains lubricity within the joints. Without the synovial fluid your cartilage would soon become worn away and your bones would grind together, eventually seizing up. By taking hyaluronic acid orally as a supplement, you can help to maintain healthy joints by maintaining the integrity of the cartilage and the quality of the synovial fluid.

Because the cartilage contains no blood vessels, it is reliant on the synovial fluid to keep it supplied with nutrients, and specifically with HA which is a large part of its structure. Without this important polysaccharide your body would not be able to function: no Mobility, dry flaky skin and poor or no eyesight.

Hyaluronic Acid and Your Skin

Hyaluronic acid occurs in the lower layers of your skin where it helps to maintain a smooth and full appearance to your skin due to its hygroscopic nature in absorbing up to a thousand times its weight of water. For this reason HA is frequently used in skin moisturizing treatments and lotions.

HA is not found inside body cells, but appears to be restricted to the extracellular regions between cells where its moisturizing properties are critical in maintaining suppleness. Elastin requires copious quantities of water to remain elastic or it would otherwise become brittle: that is why our skin looks dry and wrinkled when we age. It is due to a lack of moisture: the moisture that hyaluronic acid can bring to the table. The problem is that HA reduces with age and in order to maintain our youthful looks we have to take a supplement.

Hyaluronic acid doesn't last long in your skin: it has to be renewed constantly and each day about 50% of the HA content of your skin is lost. It takes about two weeks for the same degree of loss to occur in the synovial fluid of your joints. The look of your skin depends to a very large extent on the extracellular matrix, or what is contained between your skin cells. The more moisture there then the smoother and plumper your skin will appear.

As you age, your hyaluronic acid production drops and so your skin becomes increasingly more depleted of moisture. This causes it to dry up and wrinkle. Were there one substance that I would choose as the elixir of life it would be HA, because by taking a regular supplement your natural daily loss is replenished and your skin is given a hand to maintain its soft, moist plumpish look that helps you to keep you looking young.

Hyaluronic Acid and Your Eyes

The vitreous humor is the liquid inside your eyeball, and it contains a large amount of hyaluronic acid. It helps absorb shock and to maintain the shape of the eyeball. The HA is so important that your body has developed a special set of cells known as the hyalocytes of Balazs that are believed to promote the renewal of hyaluronic acid, and also possibly its breakdown.

There is still a lot of research going on into this but the importance of HA in the vitreous humor and other aqueous area of your body is not in question. It helps to retain water and give structure to the liquid media within your body, whether that is between the bones of your joints, in the dermal and epidermal regions of your skin to keep it supple, or in your eyeball. In fact, it is believed to take up 70% - 80% of your eye, and helps to keep the retina in place exactly where it has to be for your eyesight to work.

Cogent Solutions Group LLC - Baxyl 6 fl oz Syrup Because Hyaluronic acid is:

a) present between the cells in every tissues in your body, and

b) a consumable, in that it gets used up rapidly, and

c) your biochemistry's ability to regenerate it reduces with age,

a supplement is the ideal way in which to maintain its levels in your extracellular system. In some instances injections are given, particularly in expensive anti-wrinkling treatment, but studies have shown that hyaluronic acid baxyl taken as an oral supplement shows an improvement after an average of 3 months treatment.

It should be understood that the average person has around 15 grams hyaluronic acid in their body, of which 5 grams is continually degraded and synthesized daily. When you reach an age that your ability to generate HA is impaired, then an oral supplement will be less expensive than injections, the hyaluronic acid of which will also be degraded with time. It won't be long before you need more treatment, and oral supplements are less expensive than private hypodermic injections.

A Hyaluronic acid supplement baxyl can be taken to improve the suppleness and appearance of youthful skin, help maintain the integrity of your eyesight and help to reduce the symptoms of arthritis and many other conditions brought on by a reduction in the synovial fluid and hydration of the skeletal and connective tissues of your body. In other words, it helps to keep you looking younger for longer and to keep your joints and your eyesight in good health.

Have you had your daily dose of hyaluronic acid today?

Baxyl is a liquid form of hyaluronic acid that is easy to take and easily assimilated into the body because its a liquid.

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Are you experiencing Joint pain? Give Baxyl hyaluronic Acid liquid a try
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Date: December 10, 2010 02:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Are you experiencing Joint pain? Give Baxyl hyaluronic Acid liquid a try

Baxyl - Liquid Hyaluronic acid

Baxyl is an effective and convenient way to:

* Promote healthy joint Mobility and lubrication*

* Enhance the maintenance of cartilage and joint tissues*

* Stimulate bone health by increasing bone mineral density*

* Promote healthy skin aging and support the maintenance of smooth skin*

* Support tissue health and function in the lining of the stomach, intestines, and bladder.*

Baxyl - Hyaluronic Acid Works

Hayluronic acid works, get this powerful substance into the body faster by taking it in liquid form.

If you are experiencing joint pain, give baxyl a try!

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Ginger Root
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Date: September 29, 2009 01:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ginger Root

Medicinally, ginger has been used for thousands of years. The herb was first used in tropical Asian climates. The Greek historian Dioscorides recommended ginger for the stimulation of the production of digestive juices and also to fight chills and colds. This herb has been used by the Chinese for many ailments including colds, nausea, and indigestion. The introduction of ginger to America is credited to the Spaniards during the sixteenth century. From 1820 to 1873, ginger was listed in the U.S. Pharmacopoeia.

Ginger is believed to have blood-thinning properties, along with the ability to lower blood cholesterol levels. The herb is both a blood stimulant and a cleansing herb. Ginger is also used for respiratory problems like colds, sore throats, bronchitis, congestion, headaches, and pain. This herb is also known to help with nausea, kidney problems, heart problems, fever, vomiting, cramps, and in herbal combinations to aid in the effectiveness of other herbs. Ginger is well known for its medicinal properties, as it is used for a variety of ailments including menstrual symptoms, inflammation, arthritis, high cholesterol, liver problems, gastrointestinal problems, and motion sickness.

Recent studies have been very convincing as to the value of ginger. This herb contains terpenses, which are chemically similar to those found in camphor and turpentine. Additionally, researchers believe that there are two natural antibiotics that have been found in ginger. Ginger has been found to stop the growth of bacteria and also has the ability to relieve dizziness and motion sickness. This herb may help in preventing heart attacks and also contains anti-inflammatory agents. Studies involving seven patients with rheumatoid arthritis who have tried numerous conventional drugs, which provided only temporary or partial relief, were given ginger. All of the patients reported significant improvement, pain relief, reduction in swelling, and improved Mobility from the ginger therapy. Additional studies found similar results, with 75 to 100 percent of the patients having relief and improvement as a result of ginger supplementation. Of all its effects, ginger is probably best known for its positive effect on the gastrointestinal system. One study found that powdered ginger was more effective in treating motion sickness than some common over-the-counter treatments, without causing drowsiness. Out of thirty-six volunteers for the trial, the twelve who were given ginger did better than the twelve who received an over-the-counter preparation and the twelve who received a placebo. Ginger contains zingibain, which is a digestive enzyme that is beneficial for digestion. Ginger root may have potential for easing the morning sickness that is often associated with the early months of pregnancy.

The root of the ginger plant is used to provide alterative, antacid, anti-inflammatory, carminative, diaphoretic, diuretic, emmenagogue, febrifuge, rubefacient, sialagogue, and stimulant properties. The primary nutrients found in this herb are calcium, iron, magnesium, phosphorus, potassium, protein, sodium, and vitamins A, B-complex, and C. Primarily, ginger is extremely beneficial in treating bronchitis, childhood diseases, poor circulation, cods, colic, colitis, stomach cramps, diarrhea, dizziness, fatigue, fevers, flu, gas, gastric disorders, headache, heart problems, indigestion, morning sickness, motion sickness, nausea, sore throat, and vomiting. Additionally, this herb is very helpful in dealing with colon problems, coughs, uterine cramps, hemorrhage, intestinal problems, kidney problems, paralysis, sinus problems, and toothaches.

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Boswellia Extract
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Date: June 11, 2009 06:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boswellia Extract

The boswellia family of trees are specifically known for their fragrant, gummy sap, which possesses many medicinal uses. Among these, especially, if the use as an anti-inflammatory. It is believed that the frankincense of the bible was actually an extract from the resin of the tree. Boswellia, which is also known as boswellin, has a long history of use in Ayurvedic healing. The resin is called salai guggal and has been used to treat asthma, arthritis, various inflammatory conditions, and to relieve joint pain and pain that results from sports injuries. The resin of the boswellia tree is also though to be helpful for treating back pain as well as some other chronic intestinal disorders.

The boswellia plant is a genus of trees that are known mainly for their fragrant resin. This resin has many pharmacological uses, particularly as anti-inflammatories. There are four main species of boswellia, producing true frankincense. Each type of resin is available in various grades. These grades depend upon the time of harvesting. The resin of the boswellia plant is hand sorted for quality. Anyone who is interested in frankincense is advised to obtain a small sample from each reputable dealer to determine the difference between each resin.

Boswellic acids are the main compounds that are believed to be at the source of boswellia’s anti-inflammatory properties. These acids have the ability to inhibit the enzymes that induce pain and inflammation in the body.

A few studies have been conducted on boswellia’s effect on sports injuries and arthritis. Among these, some have shown that boswellic acids may contain anti-inflammatory benefits that are extremely powerful. These benefits are similar to those found in ibuprofen and aspirin. One study done on rheumatoid arthritis patients found that pain and swelling were reduced after three months of treatment with boswellia. Those who used boswellia occasionally reported mild gastrointestinal distress, like heartburn and nausea, but there were no other reports of serious side-effects.

Boswellia has a long tradition of safe and effective use as a mild anti-inflammatory to alleviate pain and stiffness. It is also used to enhance Mobility without serious side effects. However, further research is needed to confirm the long-term safety and effectiveness of this extract. Boswellia seems to be best taken as needed in order to reduce pain and stiffness, as opposed to being taken regularly as a maintenance herb.

The resin of boswellia is used in many herbal formulas because of its analgesic and anti-inflammatory properties. Primarily, this extract is most useful in dealing with arthritis, asthma, inflammatory conditions, joint pain, and sports injuries.

A boswellia standardized extract is recommended by many doctors. When dealing with rheumatoid arthritis or osteoarthritis, 150 mg of boswellic acids are taken three times per day. For example, if an extract contains 37.5% boswellic acids, 400 mg of the extract would be taken three times daily. Treatment with boswellia should generally last between eight and twelve weeks. Generally, boswellia is safe when used as directed. Rare side effects include diarrhea, skin rash, and nausea. Any inflammatory joint condition should be closely monitored by a health care professional. To date, there are no well-known drug interactions with boswellia.

Boswellia comes in capsule form at your local or internet health food store. When making a purchase always read the label to ensure that the product is standardized to its active acids to ensure quality and purity and to ensure that the herb when taken regularly will function as intended.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Boswellia is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Cetyl Myristoleate
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Date: May 08, 2008 03:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cetyl Myristoleate

Cetyl myristoleate is a fatty acid ester used largely as a dietary supplement to support joint Mobility and the immune system. Chemically it is a natural hexadecyl ester of cis-9-tetradecanoic acid, an unsaturated fatty acid commonly known as myristoleic acid.

The acid is found naturally in fish and whale oils, and also in butter and kombo butter from the kombo nut. The ester is of a buttery consistency at normal room temperatures, and turns waxy when cooled, and it has no known uses other than as a health supplement, particularly for the treatment of arthritis and other inflammatory and immune system problems.

The substances appear to have similar therapeutic characteristics to unsaturated essential fatty acids, but with a stronger and more long lasting effect. It also appears to work in three distinctly different ways in that it acts as a joint lubricant, supports the immune system and functions in the same way as essential fatty acids.

Arthritis is a disease that has reached epidemic proportions worldwide, and it is estimated that more than 50 million Americans are affected by it. Until recently it was believed to be a disease of the aged, or associated with physical injury, but is now known to be more complex than that, with many manifestations and causes. Because of this, no single treatment is effective with all forms of arthritis, but cetyl myristoleate is the new kid on the block that is believe to make a significant contribution to the treatment of non-infective forms of the disease.

However, it was not always known, and a search in the textbooks for cetyl myristoleate prior to 1977 would have yielded nothing. Why 1977? It started with Harry W Diehl, a sugar chemist with an interest in the treatment of arthritis. While carrying out research on arthritis in mice, he was working on thin layer chromatographic analysis of a methylene chloride extract of macerated mice. He noticed a separation that was unknown to him, which was subsequently identified as cetyl myristoleate.

He had been unable to induce arthritis in mice, and believed that if he found out how to do that, then he should also be able to establish what made the mice immune to the disease, and so establish a cure. He soon established that it was this cetyl myristoleate circulating in the blood that protected the mice, and then found a way of synthesizing it in the lab by esterifying myristoleic acid.

Since the compound was unknown at that time Diehl patented it in 1977, hence the date. Apart from in mice, it has subsequently been found only in whale oil and in one of the glands of the male beaver, with no other known sources at the time of writing. There have been several studies that have supported the effect of cetyl myristoleate on arthritis, the first human study being in 1995 when 46 out of 48 arthritis patients showed significant improvement in articular Mobility and reduction in pain. Others since have demonstrated similar results.

So how does it work? What is the mechanism by which this hitherto unknown substance helps to relieve the symptoms of osteo and rheumatoid arthritis? Being a fatty acid ester, cetyl myristoleate possesses lubricant properties, and one of its properties is to supplement the synovial fluid that lubricates the joints and tendons. This helps to keep the joints moving freely, and reduces their tendency to grind when the connective tissue wears. It also lubricates entire muscle groups, allowing them to slide over each other more freely, and also over bones allowing a smoother movement of the joints.

The second way, in which it operates, by supporting the immune system, is particularly appropriate to the treatment of rheumatoid arthritis which is caused by the immune system attacking the body’s own joint and connective tissue. In this respect, cetyl myristoleate has also been found effective in treating other immune system conditions such as multiple sclerosis and lupus erythematosus.

Finally, it also possesses the mediation effect on the inflammatory reaction possessed by other essential fatty acids. This helps to reduce the effect of inflammation that causes much of the swelling and pain of arthritic conditions, although it occurs much faster than with other fatty acids. When taken together, all of these effects have a powerful effect in reducing the unpleasant symptoms of both osteoarthritis and rheumatoid arthritis. Swelling is reduced, Mobility is improved and pain is alleviated. Improvements have been reported by sufferers of both types of arthritis, and in fact it is reported that Harry Diehl successfully treated his own arthritis with the substance before any other human tests had been carried out.

Cetyl Myristoleate is now used word-wide in significant quantities, and there have as yet been no confirmed reports of adverse side effects. However, as with many otherwise safe supplements, it is recommended not to be taken by pregnant or lactating women until it has been proved to definitely have no side effects on the fetus or young babies.

Although there is no definitive scientific evidence of the effectiveness of the substance in relieving the symptoms of arthritis, there is an overwhelming body of evidence from those that have used it world wide. The accepted treatment is by non-steroidal anti-inflammatory drugs (NSAIDs), and with over 16,0000 NSAID-related deaths in the USA alone each year, cetyl myristoleate is certainly worth considering as an alternative for arthritis sufferers. Not only that but there is a very significant price differential, with NSAIDs costing 5 – 10 times that of cetyl myristoleate.

Among the other benefits that people using the substance have reported are beneficial effects on psoriasis, hepatitis, high blood pressure, eczema, allergies, headaches and many more. Although many of these might be coincidence or psychosomatic, it cannot just be coincidence that many of them, such as psoriasis and allergies, are related to the immune system.

However, anybody with asthma or a history of severe allergic reactions should consult their physician before using the substance. That aside, there is more than enough popular evidence to indicate that cetyl myristoleate is effective in the treatment of arthritis in all its forms, and also good for your general state of health and wellness.



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Support Healthy Joint Function With Discount Vitamins
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Date: November 22, 2007 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Support Healthy Joint Function With Discount Vitamins

The joints are very important to your Mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime.

Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones.

Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain.

Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue.

A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders.

A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints.

The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover.

Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids.

Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks.

Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage.

Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement.

It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that.

That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results.

Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density.

There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium.

You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.



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Memory And Focus
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Date: May 08, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Memory And Focus

Memory & Focus

 

Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and Mobility as we age.

This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.

The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.

In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.

 

Q. What is the difference between age related memory decline and dementia?

A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.

While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.

After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.

Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.

While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.

 

Q. Are any types of memory and focus loss reversible?

A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.

Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.

A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.

 

Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?

A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..

Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.

 

Q. How can nutritional supplements improve memory and focus?

A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.

One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.

Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.

In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.

 

Q. Hoe does Bacopa monnieri help memory and focus?

A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in India and has a long history as a natural medicine. In a recent study, bacopa was compared to a placebo in its effect on memory. Adults between the ages of 40 and 65 were divided into 2 groups. Half got the bacopa and half got a placebo. Researchers, who didn’t k now which patients got the bacopa, tested both groups’ memory before the study, at three months, and when the study ended six weeks later. The results showed the group taking the bacopa extract was able to remember new information much better than the group taking the placebo.

 

Q. How does alpha lipoic acid help memory and focus?

A. Alpha lipoic acid (ALA) is a vitamin-like coenzyme that prevents memory and focus problems we might have later on. ALA is an incredibly powerful antioxidant that works especially well with other antioxidants. An antioxidant’s job is to disarm damaging free radicals, those naturally occurring molecules that damage cells and cause disease. ALA has potent antioxidant action in almost all the tissues of the body, helps generate energy from food an oxygen, can get directly to the nerves, and plays an important role in the “antioxidant network”.

Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly, ALA’s effect in the illness has been studied extensively. Researchers have learned that ALA not only prevents free radical damage in Alzheimer’s disease, but also regulates protective chemicals in the brain that help improve symptoms.

In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given ALA supplements for an average of 11 months. At the end of the study, the participants were tested again. The results showed that every person had higher scores on the thought and memory tests than they had at the beginning.

ALA is unique among antioxidants, as it can neutralize free radicals in both the fat and the water of cells. In contrast, the well known vitamin C is only water-soluble, while the popular antioxidant vitamin E is only soluble in fat. Because ALA is easily absorbed, enters cells and tissues in a highly usable form, performs a variety of antioxidant actions (including rejuvenation of other antioxidants), and is both fat and water soluble, many researchers label ALA an “ideal antioxidant”.

 

Q. How do vitamins B12 and B6 help memory and focus?

A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.

Like ALA, vitamins B6 and B12 help prevent memory and focus problems further on down the road. One important recent discovery is the role of homocysteine in brain diseases. These important B vitamins can reduce homocysteine, an amino acid (the building blocks of protein) that is produced in the human body. Homocysteine irritate s blood vessels, makes it easier for blood to clot, and can cause cholesterol to become more harmful.

Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.

Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.

 

Q. What about folic acid?

A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.

An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.

Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.

 

Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?

A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.

Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.

It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.

 

Conclusion

Dealing with age-related memory loss may be both frustrating and frightening. As the population of America gets older, dementia is continuing to affect a larger proportion of society. Prevention of these devastating diseases has become increasingly important.

In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and ALA can improve age-related memory loss and potentially prevent the development of Alzheimer’s disease and other dementias as we age.



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Learn about Bone Health!
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Date: April 20, 2007 12:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Learn about Bone Health!

Bone Health

Approximately 44 million American women and men aged 50 and older have osteoporosis (severe bone loss) or osteopenia (mild bone loss), with women being affected about twice as often as men. At least 1.5 million fractures of the hip, vertebra (back or neck), or wrist occur each year in the United States as a result of osteoporosis, and the annual cost of treating this disorder is nearly $14 billion and rising. Unfortunately, the toll in human suffering and loss of independence is even greater.

In this issue of Ask the Doctor, we will discuss the risk factors for osteoporosis and some key nutrients you can add to your diet that can minimize bone loss and reduce your chances of developing this disease.

Q. What are the risk factors for osteoporosis?

A. Small body frame, underweight, Caucasian or Asian race, a sedentary lifestyle, cigarette smoking, excessive alcohol or caffeine intake, high intake of carbonated beverages (especially colas), and having other family members with osteoporosis all increase personal risk of developing the disease. Certain medical conditions, including diabetes, celiac disease, hyperthyroidism, rheumatoid arthritis, chronic obstructive lung disease, hyperadrenalism, and hyperparathyroidism, are all associated with an increased risk of osteoporosis. Some medications increase the rate at which bone is lost; these include drugs prescribed for the treatment of seizures, drugs used for blood thinning, steroids such as prednisone, aluminum-containing antacids, and loop diuretics (furosemide {Lasix}).

Q. Isn’t bone loss just a normal consequence of aging?

A. Although bone mass normally declines after the age of 35, bone loss severe enough to cause fractures after just minor trauma (such as bump or fall) seems to be a relatively new phenomenon. Osteoporosis was rare in the late 19th century, and it was not until around 1920 that the condition began to attract attention among doctors. Since that time, the percentage of people who develop osteoporosis has continued to increase. For example, the age-adjusted prevalence of osteoporosis in England and Sweden double between 1950 and 1980. In addition, the percentage of elderly people with osteoporosis in some developing countries is lower than that of elderly Americans, despite lower calcium intakes in the developing countries, further suggesting that osteoporosis is a disease of modern civilization.

Q. Can osteoporosis be prevented?

A. Engaging in regular weight bearing exercise, avoiding excessive consumption of alcohol and caffeine, and quitting smoking will slow the rate of bone loss. Eating adequate, but not excessive, amounts of protein also enhances bone health. In addition, a growing body of research has shown that supplementing with various vitamins and minerals may not only help prevent, but in some cases actually reverse, bone loss. At least 15 different nutrients have been found to play a role in bone health.

Q. What type of calcium is best?

A. For most people, calcium salts are absorbed about the same, between 30% and 40% of the administered dose. People who low stomach acid (hypochlorhydria) should not use calcium carbonate, because that form of calcium is absorbed poorly in the absence of stomach acid. Calcium phosphate may be preferable for many older people, because phosphorus is necessary for normal bone formation, the phosphorus intake of older people is often low, and calcium supplements inhibit the absorption of phosphorus.

Also, calcium bound to phosphorus is the form in which calcium in the bone is stored, and it has a much greater bone activity than other forms.

Q. How much vitamin D is needed to promote strong bones?

A. Because vitamin D is produced when the ultraviolet rays from the sun hit skin, people who stay out of the sun, wear sunscreen, or live in a northern latitude (such as Boston or Seattle) where less ultraviolet light reaches the skin, are at increased risk of vitamin D deficiency. In addition, aging decreases a person’s ability to synthesize vitamin D in the skin. Results from five research trials on vitamin D found that supplementation with 700-800 IU of vitamin D per day decreased the number of hip fractures by 26%, but 400 IU per day was ineffective. In addition to enhancing bone health, vitamin D improves nerve and muscle function in older people, thereby reducing their chances of falling down. Supplementation of elderly women with 800 IU of vitamin D per day has been shown to decrease the number of falls by about 50%.

Q. Is that much vitamin D safe?

A. The Food and Nutrition Board of the Institute of Medicine established a “safe upper limit” of 2,000 IU per day in 1997. More recent research suggests that up to 4,000 IU of vitamin D per day is safe for the average person. However, you likely don’t need nearly this much to address most bone issues.

Q. Why would nutrients besides calcium and vitamin D is important?

A. Bone is living tissue, constantly remodeling itself and engaging in numerous biological functions. Like other tissues in the body, bone has a wide range of nutritional needs. The typical refined and processed American diet has been depleted of many different vitamins and minerals, some of which play a key role in promoting bone health. Not getting enough of one or more of these micronutrients may be and important contributing factor to the modern epidemic of osteoporosis. In addition, supplementing with calcium may cause a loss of magnesium, zinc, silicon, manganese, and phosphorus, unless these nutrients are also provided.

Q. What nutrients besides calcium and vitamin D promote healthy bones?

A. Magnesium, zinc, copper, manganese, vitamin K, boron, strontium, silicon, folic acid, vitamin B6, vitamin B12, phosphorus, and vitamin C have all been shown to play a role in bone health. Following is a brief description of the role that each of these 15 nutrients play in building healthy bones.

Calcium: A component of the mineral crystals that make up bone.

Vitamin D: Enhances calcium absorption, prevents falls by improving nerve and muscle function.

Magnesium: Important for bone mineralization (accumulation of minerals which form bones). Magnesium deficiency is associated with abnormal bone mineral crystals in humans. In an open clinical trial, magnesium supplementation increased bone mineral density by an average 5% after 1-2 years in postmenopausal women.

Copper: Laboratory research has found that copper promotes bone mineralization and decreases bone loss, and that osteoporosis can develop if the diet is deficient in copper. Western diets often contain less copper than the amount recommended by the National Academy of Sciences. In a 2-year double-blind trail, copper supplementation reduced bone loss by 90% in middle-aged women, compared with a placebo.

Zinc: Like magnesium, zinc is important for bone mineralization, and also has been shown to decrease bone loss. Low dietary zinc intake was associated with increased fracture risk in a study of middle-aged and elderly men. The zinc content of the diet is frequently low; a study of elderly low-income people found they were consuming only half the Recommended Dietary Allowance for this mineral.

Manganese: Plays a role in the creation of the connective-tissue components of bone. Manganese deficiency in laboratory tests resulted in low bone mineral density and weak bones. Manganese deficiency may be associated with the development of osteoporosis.

Boron: Supports creation of bone-protecting hormones such as estrogen, testosterone, and DHEA. Boron supplementation prevented bone loss in experimental studies. In human volunteers consuming a low-boron diet, boron supplementation decreased urinary calcium excretion by 25-33%, a change that may indicate reduced bone loss.

Silicon: Plays a role in the synthesis of the connective-tissue components of bone. Silicon deficiency has been associated with bone abnormalities. In an observational study, higher dietary silicon intake correlated with higher bone mineral density. In a clinical trial, administration of an organic silicon compound increased bone mineral density of the femur (or thigh bone) in postmenopausal women.

B vitamins (folic acid, vitamin B6, and vitamin B12): These three B vitamins have been shown to lower blood levels of homocysteine, a breakdown product of the amino acid methionine. An elevated homocysteine concentration is a strong and independent risk factor for fractures in older men and women. Homocysteine levels increase around the time of menopause, which may explain in part why bone loss accelerates at that time. In a 2-year double-blind trial, supplementation of elderly stroke patients with folic acid and vitamin B12 reduced the number of hip fractures by 78%, compared with a placebo.

Strontium: This trace mineral is incorporated into bone and appears to increase bone strength. It also stimulates bone formation and inhibits bone breakdown. Controlled trials have demonstrated that strontium supplementation of postmenopausal women increases bone mineral density and decreases fracture risk.

Vitamin K: Best known for its effect on blood clotting, vitamin K is also required for the creation of osteocalcin, a unique protein found in bone that participates in the mineralization process. The amount of vitamin K needed for optimal bone health appears to be greater than the amount needed to prevent bleeding. Vitamin K levels tend to be low in people with osteoporosis. In randomized clinical trials, supplementation of postmenopausal women with vitamin K prevented bone loss and reduced the incidence of fractures.

Q. Which form of vitamin K is best?

A. Two forms of vitamin K compounds are present in food: vitamin K1 and vitamin K2. Vitamin K1 (also called phylloquinone) is present in leafy green vegetables and some vegetable oils, and vitamin K2 is found in much smaller amounts in meat, cheese, eggs, and natto (fermented soybeans).

To make things a little more complicated, Vitamin K2 itself can occur in more than one form. The two most important to this discussion are menaquinine-4 (MK-4, also called menatetrenone), which is licensed as a prescription drug in Japan, and menaquinone-7 (MK-7), which is extracted from natto.

Research suggests that MK-7 from natto may be an ideal form of vitamin K. The biological activity of MK-7 in laboratory studies was 17 times higher than that of vitamin K1 and 130 times higher than that of MK-4. After oral administration, MK-7 was better absorbed and persisted in the body longer, compared with MK-4 and vitamin K1. Although both have shown ability to prevent osteoporosis in laboratory research, a much lower dosage (600 times lower) of MK-7 is required, compared to MK-4, to obtain beneficial effects.

Thus, MK-7 has greater biological activity, greater bioavailability, and possibly more potent effects on bone, compared with other forms of vitamin K. The potential value of MK-7 for bone health is supported by an observational study from Japan, in which increasing natto consumption was associated with a lower risk of hip fracture. While additional research needs to be done, the available evidence suggests that the best forms of vitamin K for long-term use at physiological doses are MK-7 and vitamin K1.

Q. Why is strontium so important in building strong bones?

A. Strontium is of great interest to bone health researchers and has been studied in very high doses. Surprisingly, lower doses are not only safer for long-term supplementation, but may in fact have a greater impact on bone health than very high doses. Too little, and bone density is impaired; too much and health may be impaired. This is a case where dosing needs to be just right for optimal impact. Therefore, until more is known, it is wise to keep supplemental strontium at less than 6 mg per day.

Q. Can people taking osteoporosis medications also take bone-building nutrients?

A. Because nutrients work by a different mechanism than osteoporosis drugs, nutritional supplements are likely to enhance the beneficial effect of these medications. Calcium or other minerals may interfere with the absorption of biphophonates such as alendronate (Fosamax) or etidronate (Didronel). For that reason, calcium and other minerals should be taken at least two hours before or two hours after these medications. Also, it is always best to discuss the supplements you are using with your healthcare practitioner to create an integrated health plan.

Final thoughts…

Bone health ramifications extend beyond osteoporosis and fractures. Bone health is essential for freedom of movement, safety, comfort, independence and longevity. Weak bones do not heal well – sometimes they never heal at all. Osteoporosis-related fractures rob us of our Mobility and consign thousands of Americans to walkers and wheelchairs every year. In fact, 40% of people are unable to walk independently after a hip fracture, and 60% still require assistance a year later. The most terrible consequence of fractures related to osteoporosis is mortality. The impairment of the ability to move around freely can cause pneumonia and skin damage leading to serious infections. It is estimated that suffering a hip fracture increases the risk of dying almost 25%. Making bone health a priority now will allow you to reap health dividends for many years to come.



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Glucosamine Sulfate and Chondroitin Sulfate
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Date: March 28, 2007 11:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine Sulfate and Chondroitin Sulfate

Glucosamine Sulfate and Chondroitin Sulfate

Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years.

While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of glucosamine sulfate (GS), which actually addresses the underlying joint destruction.

Q. What is osteoarthritis?

A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work.

A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed synovial joints, and have the greatest range of movement and Mobility of human joints. To allow such Mobility, synovial joints have a unique structure.

The bones that form synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called synovial membrane. The membrane secretes synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement.

The cartilage of synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; synovial joints move easily. Secondly, synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement.

Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones.

Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain.

People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days.

Q. What causes osteoarthritis?

A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse.

Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees.

Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage.

Q. Can osteoarthritis be prevented?

A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures.

Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis.

Q. What treatments are available for osteoarthritis?

A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis.

These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur.

Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur.

Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself.

That is why many believe glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve synovial joint health. And they do this without potentially life-threatening side effects.

Q. How do GS and CS work?

A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints.

There is even more good news. When glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness.

Glucosamine occurs naturally in the body and is found in synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints.

In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study glucosamine, they discovered GS can reduce synovial joint inflammation. This explains why people felt better after taking it.

Q. What has additional study of GS and CS revealed?

A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better.

GS is the form of glucosamine used in research. It’s the sulfate salt of glucosamine and breaks down into glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis.

CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS.

Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together?

A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies.

Q. Why is it important to take low-molecular weight CS?

A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment.

However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS.

This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the synovial fluid of joints where it’s needed.

Q. Are there other supplements that can help osteoarthritis?

A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis.

Folic acid and vitamin B can reduce the number of tender joints and increase joint Mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis.

Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals.

Q. Is there anything else I can do for joint pain and stiffness?

A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home.

Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints.

The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis.

One important last thought

When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis.

Conclusion

Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health.

Buy Glucosamine and Chondroitin Sulfate at Vitanet ®, LLC

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Benefits - Supports joint function and tissue health*
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Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased Mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint Mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and Mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.



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JOINT HEALTH
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Date: December 22, 2005 09:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: JOINT HEALTH

Glucosamine & Chondroitin - JOINT HEALTH

Everyone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints.

Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of Mobility. These nutrients are referred to as “chondroprotective agents,” and include glucosamine and chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with glucosamine and chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function.

Glucosamine and chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.

GLUCOSAMINE

Glucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on glucosamine sulfate and glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion.

The 106 patients on placebo had a progressive jointspace narrowing, while participants taking glucosamine experienced no significant joint-space loss, indicating glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of glucosamine sulfate or placebo daily for 30 days. The patients treated with glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5

CHONDROITIN

Chondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While glucosamine helps manufacture and maintain cartilage, chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6

NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both glucosamine and chondroitin as separate products, as well as in powder and lotion forms.

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Glucosamine & Chondroitin - JOINT HEALTH
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Date: December 22, 2005 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine & Chondroitin - JOINT HEALTH

  • Supports Healthy Joint Structure and Function
  • Supports Mobility and Ease of Movement

References:
1) Balch, James F. et. al. ; Prescription For Nutritional Healing 3 rd rd rdPrescription Edition Edition ; Avery; Penguin Putnam; 2000
2) Benedikt, H.; Glycosaminoglycans And Derivatives For Treatment Of Arthritis; Chiropractic Products, May 1997, pp. 92-95
3) Reginster, Jean Yves et. al.; Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial; The Lancet, 2001, Vol. 357, No. 9252 4) Bassleer, C. et. al.; Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro; Osteoarthritis and Cartilage, 1998, 6, 427-434
5) Drovanti, A. et. al.; Therapeutic Activity of Oral Glucosamine Sulfate in Osteoarthritis: A Placebo-Controlled, Double-Blind Investigation; Clinical Therapeutics, Vol. 3, No. 4, 1980, pp. 260-272
6) Morreale, P. et. al.; Comparison of the Antiinfl ammatory Effi cacy of Chondroitin Sulfate and Diclofenac Sodium in Patients with Knee Osteoarthritis; Journal of Rheumatology, 1996, 23:8, pp. 1385- 1391



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Nattokinase Fact Sheet
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Date: December 08, 2005 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nattokinase Fact Sheet

Nattokinase Fact Sheet

Neil E. Levin, CCN, DANLA 8/8/05

LIKELY USERS: People seeking to support heart health and healthy circulation.1-6

KEY INGREDIENTS: Nattokinase, an enzyme

STRUCTURE/FUNCTION USE: Nattokinase is an enzyme isolated from Natto, a traditional Japanese fermented soy food. Natto has been consumed safely for thousands of years for its numerous health benefits. More recently, both clinical and non-clinical studies have demonstrated that Nattokinase supports heart health and promotes healthy circulation. Each serving of NOWR Nattokinase provides 2,000 FU (Fibrinolytic Units) to help keep already healthy levels of blood clotting factors within a normal range. 1-6

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: An assay of 2,000 FU (Fibrinolytic Units) is equivalent to 160 IU on the Urokinase assay. The FU assay measures Nattokinase activity by using the fibrin plate method and measuring the absorption of released low-molecular weight substances.7 NOW Nattokinase is made from non-GE (non-genetically engineered) bacteria (Bacillus subtilis var. Natto) grown on non-GE soybeans and standardized on a base of non-GE, corn-derived maltodextrin.

SERVING SIZE & HOW TO TAKE IT: Take one vegetarian Vcap once or twice a day between meals (without protein).

COMPLEMENTARY PRODUCTS: Vein SupremeTM, Tru-E Bio ComplexTM, Pycnogenol®, garlic, and cayenne

CAUTIONS: None.

SPECIFIC: People with blood coagulation disorders or who take anticoagulant (“blood thinning”) medications (including aspirin) should consult a physician before use. Do not take if prone to bleeding. Unlike some other brands, NOWR Nattokinase contains no Vitamin K (K1 or K2), which would enhance clotting.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S (1995) Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull 18(10):1387-1391
2. Sumi H, Hamada H, Nakanishi K, Hiratani H (1990) Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol 84(3):139-143.
3. Suzuki Y, Kondo K, Ichise H, Tsukamoto Y, Urano T, Umemura K (2003) Dietary Supplementation With Fermented Soybeans Suppresses Intimal Thickening. Nutrition 19:261-264.
4. Suzuki Y, Kondo K, Matsumoto Y, Zhao B-Q, Otsuguro K, Maeda T, Tsukamoto Y, Urano T, Umemura K (2003) Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci 73:1289-1298.
5. Ito H, Suzuki T (2002) Effect of oral administration of nattokinase extract on blood Mobility. Society of Analytical Bio-Sciences 25(4):1-5.
6. An Open Clinical Pilot Study to Evaluate the Safety and Efficacy of Natural Super Kinase as an Add-On Oral Fibrinolytic Agent to Low Molecular Weight Heparin and Anti-Platelets in Acute Ischaemic Stroke. (no authors listed) (2004)
7. Method: J of Agri Food Chem, Vol 48 (2000) P3, 210-213, 216



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- US Center for Disease Control, 2005
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Date: December 07, 2005 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: - US Center for Disease Control, 2005

“Forty-three million Americans report that a doctor told them they have arthritis or other rheumatic conditions. Another 23 million people have chronic joint symptoms but have not been diagnosed with arthritis. Arthritis is the leading cause of disability in the United States, limiting the activities of more than 16 million adults.” - US Center for Disease Control, 2005

This is of alarming concern, especially if you’re one of the nearly 60 million US adults who live with a joint disorder. Clearly, you don’t need to be reminded of what a struggle it can be. Mundane tasks become major, and major tasks become painful reminders of what life was like when your joints were strong and seemingly indestructible. Many sufferers lose hope, while others hopelessly lose out on so many of life’s activities.

Over the past ten years, notable advances in the nutritional sciences have paved the path for landmark products such as Glucosamine, SAMe, Chondroitin, MSM, and others. As a result, millions have found relief in these products and continue to use them in their quest towards healthy Mobility. Fortunately, the science behind these popular joint support supplements has done nothing but steadily improve. Celadrin® is perhaps the most convincing proof to date. Let’s examine.

In short, Celadrin® is novel blend of acetylated fatty acids, esters and other synergistic agents that enhance cell membranes throughout the body, resulting in greater Mobility and more normalized joint function. The extremely high user success rate and virtually complete absence of side effects has helped Celadrin® rise to the rank of joint support extraordinaire. Yes, this is a bold statement. However, just one look at the supporting research is enough to convince even the most skeptical critics of what a true breakthrough it is. Celadrin®’s ability to provide fast, cumulative relief continues to be evidenced by extensive clinical research, as well as a steady flow of eye-opening human trials.

Unlike popular non-steroidal anti-inflammatory drugs (NSAIDS) that simply mask joint discomfort, Celadrin® targets the source by enhancing cell membranes and restoring the vital fluids that cushion bones and joints. Ultimately, this is what makes it possible to enjoy a free range of motion without the bone-on-bone grinding that limits so many from their daily activities. Working in much the same manner that other fatty acids do, Celadrin®’s patented blend of esterified fatty acids spark positive changes at the cellular level. As this occurs, cell membranes become more responsive and less prone to articular cartilage deterioration.

“How long do I need to take it?”

Not only does it work well, studies continue to illustrate Celadrin®’s ability to work fast. This can be attributed to how easily absorbed the active ingredients are. In 2005, a University-led, placebo-controlled study examined 42 patients who struggled with knees that were…let’s just say less than fully functional. After just 30 minutes, 100% of the subjects treated with a topical form of Celadrin® reported significant improvement in joint Mobility and support. Even more impressive, each participant demonstrated continuous and restorative benefits over the course of the entire 30 day study.

“How do I use Celadrin®?”

One of the most appealing elements of Celadrin® is the flexibility that users have when it comes to taking charge of their joint health. It is available in both oral and topical forms, and each is equally effective. Some users have reported greater results by supplementing the oral form while applying the topical lotion directly to the target areas in question. Still, no two people are alike. Accordingly, the severity and nature of each individual concern will vary from person to person. Therefore, it can be wise to determine which application works best for your particular situation.

“What if I don’t have joint problems?” For openers, you’re very fortunate. If your joints are strong and fluid, Celadrin® is one of the most effortless ways to keep them that way! Cartilage breakdown is gradual, and occurs over a long, delayed, unsuspecting period of time. In many cases, there is very little warning that your knee or shoulder is about to become part of a frightening and growing statistic. Your joints may feel fine today, but you’d be amazed at how fast that can change. Think of Celadrin® as Cartilage Insurance. You may not see an immediate need to support them right now, but if they do give out, you’ll sincerely wish you had.

“What should I look for in a Celadrin® product?”

As with every dietary supplement and joint-support product, you should always look for a quality formula from a trusted, well-established manufacturer with a history of producing quality products. NOW® Celadrin® products are scientifically formulated, tested for safety and potency and guaranteed to be of superior quality. Each full serving contains 1.5 g (1500 mg) of Celadrin® along with 300 mg of MSM for additional support. NOW® Celadrin® Liposome Lotion contains 7.5 % Celadrin® along with 1.25% USP Pharmaceutical grade natural Menthol. Both are now available at fine independent health food retailers nationwide.* credits: Jayson Kroner [mailto:jayson.kroner@nowfoods.com]

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Celadrin and MSM Fact Sheet
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Date: December 07, 2005 01:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celadrin and MSM Fact Sheet

Celadrin and MSM Fact Sheet

Neil E. Levin, CCN, DANLA Certified Clinical Nutritionist, Diplomate in Advanced Nutritional Laboratory Assessment Revised 11/10/05

LIKELY USERS: People lacking flexibility or Mobility; People wanting temporary control of aches and pains; People wanting to reduce pro-inflammatory body chemicals. KEY INGREDIENT(S): Celadrin® powder 500 mg. Provides 350 mg. of actual EFAC (esterified fatty acid carbons). This is a proprietary blend of Esterified Fatty Acid Carbons of Myristate, Myristoleate, Laurate, Oleate, Palmitate and Palmitoleate in a base of tapioca and silica.

MSM 100 mg.

MAIN PRODUCT FEATURES: CELADRIN® is an all-natural proprietary matrix of esterified (cetylated) fatty acid carbons (EFAC) derived from tallow of USA-raised cattle. This product is developed through a proprietary process of esterifying oil & has been clinically tested. Celadrin promotes joint health by improving flexibility, pain management and Mobility. The myristoleic acids and the cetylated forms may alter the 5-LOX enzyme and change the leukotriene production, inhibiting inflammatory compounds.

Celadrin® may offer some noticeable benefits faster than other substances, like glucosamine and chondroitin. Though it is not a substitute for these important tissue-building nutrients. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: MSM has synergistic abilities to reduce certain substances in the body which may affect the inflammatory process.

Contains Cetyl Myristoleate (CM, CMO), but in a patented blend of other fatty acid carbons. This product (Celadrin ®) has its own clinical studies showing safety and efficacy.

Also will be available in a softgel of the same potency (350 mg. of EFAC) as of December 2005 (product 3017, 90 softgels)

SERVING SIZE & HOW TO TAKE IT: Three capsules a day, preferably with meals.

POSSIBLE SYNERGISTS: Glucosamine, Chondroitin, MSM, Joint Support Products, Manganese, Vitamin C, other Antioxidants

CAUTIONS: None.

SPECIFIC: None

GENERAL: Pregnant and lactating women, and people using prescription drugs, should consult their physician before taking any dietary supplement.

This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients.

When taking any new dietary supplement, use common sense and cautiously increase to the full-recommended dose over time, looking for possible side effects. Repeat this process for each new supplement that you start to use.

REFERENCES: 1. J Rheumatol. 2002 Aug;29(8):1708-12. Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis. Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R.
2. Anticancer Res. 2003 Jan-Feb;23(1A):453-8. Aspirin and methylsulfonylmethane (MSM): A Search for Common Mechanisms, with Implications for Cancer Prevention. Ebisuzaki K.
3. J Altern Complement Med. 2002 Apr;8(2):167-73. A Multicentered, Open-Label Trial on the Safety and Efficacy of Methylsulfonylmethane in the Treatment of Seasonal Allergic Rhinitis. Barrager E, Veltmann JR Jr, Schauss AG, Schiller RN. (allergy related inflammation)



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Utah's Inland Sea Minerals – Topical Application
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Date: November 22, 2005 09:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Utah's Inland Sea Minerals – Topical Application

Minerals provide a bounty of healing properties that have scientifically validated their use for topical applications. These applications have been shown to have powerful local and systemic effects. The health of ones skin and hair reflects inner health. Indeed, we judge the health of animals and humans alike by their outward appearance of fur or skin, respectively. The human skin is the largest organ of the body and is highly involved in the detoxification and maintenance processes of health. Skin not only excretes and eliminates toxins; it also has a tremendous capacity to absorb health supportive substances. The pharmaceutical industry frequently takes advantage of the skin’s absorptive capacity with drug therapies. Such therapies include the transdermal delivery of drugs like nicotine, hormone patches, progesterone creams and so forth. Thus, it is apparent that natural therapies can have pronounced and powerful health effects.

Clinical researchers have continued to document the clinical findings that have been observed for decades when it comes to the healing properties of topical minerals. Many of the studies on therapeutic baths have used minerals from the Dead Sea, an ancient inland sea. However, a similar and impressive array of minerals occurs in the other inland sea, the Great Salt Lake. Indeed, the high presence of magnesium from both inland seas appears to be the foremost active mineral. A comparison chart below clearly reflects the mineral analysis and similarity (see chart below). The following survey of medical research reflects a few of the many therapeutic roles for mineral salt baths. Of particular interest are the powerful effects of magnesium salts that are prevalent to both Utah’s Inland Sea and the Dead Sea that exhibit favorable effects in inflammatory disease. Arthritis:

103 patients with arthritic symptoms were treated for 1-2 weeks. They received various bath treatments with the ionic trace minerals. The study showed that the higher concentration baths offered the most impressive results. Those with the greatest physical limitation had the most pronounced improvement. Over 80 percent of the patients reported having less pain, 70 percent reported improved Mobility and 60 percent were able to decrease analgesic use (i). In a different double-blind study, the use of warm mineral baths with Dead Sea salt demonstrated a lasting effect for patients suffering from degenerative arthritis. (ii)

Skin:

In a clinical trial conducted by a leading research university in Germany, patients with atopic (eczema) skin disorders immersed their arms in a magnesium chloride rich bath. The participants immersed one arm in tap water the other in the therapeutic magnesium rich bath. The findings showed that skin hydration was improved and skin roughness and inflammation was reduced. The researchers stated “magnesium salts are known to bind water, influence epidermal proliferation and differentiation and enhance barrier repair.” (iii) Another study showed that magnesium salts when exposed to both psoriatic and healthy skin cells provided an important anti-proliferative effect (iv). Yet another study showed that the effects of mineral baths from the Dead Sea had lasting effects for upwards of a month after treatment. (v) Head to Head Comparison (vi) (vii)

Utah’s Inland Sea Composition Dead Sea Composition
Magnesium Chloride 1.04% 4.03%
Potassium Chloride 0.64% 0.72%
Sodium Chloride 9% 3.87%
Calcium Chloride 0.08% 1.64%
Chloride 15.12% 21.11%
Sulfates (SO4) 2.13% 0.03%

By: Dr. Chris Meletis N. D.

References:
• (i) Dead Sea Balneoptherapy is Osteoarthritis, Dr. Machety (Hasharon Hospital, Petach-Tikva, Israel). Published in Proceedings of International Seminar on Treatment of Rheumatic Diseases. John Wright-PSG ,1932.
• (ii) Sukenik S, Mayo A, Neumann L et al., Dead Sea bath salts for osteoarthritis of the knee, Harefuah 1995; 129(3-4):100-3, 159, 158.
• (iii) Proksch E, Nissen HP et al., Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. Int J Dermatol 2005; 44(2):151-7.
• (iv) Levi-Schaffer F, Shani J, Politi Y et al., Inhibition of proliferation of psoriatic and healthy fibroblasts in cell culture by selected Dead –sea salts. Pharmacology 1996; 52(5):321-8.
• (v) Sukenik S, Neumann L, Buskila D et al., Dead Sea bath salts for the treatment of rheumatoid arthritis. Clin Exp Rheumatol 1990; 8(4):353-7.
• (vi) The Utah Department of Natural Resources, Utah Geological and Mineral Survey Public Information Series #8, 1990.
• (vii) Gwynn, J. Wallace, The Utah Department of Natural Resources, Utah Geological Public Information Series 51, 1997.

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Research on SAMe....
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Date: October 26, 2005 12:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Research on SAMe....

Two groups of researchers have conducted analyses of trials that utilized SAM-e for mood enhancement. One meta-analysis was published in 1994. The researchers analyzed the efficacy of SAM-e in oral or injection forms based on published trials dated between 1973 and 1992. The authors concluded that there was a significant improvement of 17 to 38% seen in trials of SAM-e compared to placebo response. They state that the efficacy of SAM-e was superior to placebo and its administration caused few side effects.5 A second review was published in 2002. The authors analyzed studies in which SAM-e doses ranged from 200 to 1600 mg daily. They also found a significant effect of SAM-e in comparison to placebo, with an evident rapid onset of effect at enhancing mood.6

Promotes Joint Comfort and Mobility*

As a sulfur donor to connective tissue, SAM-e plays a major role in protecting the integrity of cartilage tissue. An in vitro trial assessed the actions of SAM-e in cultured human articular chondrocytes. At a concentration of 10 micrograms/ml, proteoglycan synthesis and sulfate residue incorporation in chondrocytes was shown to be 60% higher than control levels. Based on these results, it was shown that SAM-e has a positive influence on the growth and health of cartilaginous connective tissue.7

In a double-blind trial with 734 individuals with compromised joint health. SAM-e given orally at a dose of 1200 mg daily for 30 days was shown to significantly promote joint comfort compared to placebo, with a high level of tolerability and low incidence of side effects. The researchers concluded that SAM-e is a highly effective supplement for enhancing joint comfort.8

Another trial evaluated the response of individuals experiencing discomfort in the joints to a regimen of 1200 mg SAM-e for 1 week followed by 800 mg for the second week, and then 400 mg for weeks 3 through 8. This open trial of 20, 641 people showed a strong ability of SAM-e to enhance feelings of comfort within the joints. The treatment was rated as “very good” or “good” in 71% of the participants, with an additional 21% rating the treatment effect as “moderate”.9

In a long-term trial lasting 24 months, SAM-e was given to 108 participants with compromised joint function. Individuals were given 600 mg orally per day for the first two weeks followed by 400 mg daily for the remainder of the trial. Individuals experienced significant enhancements in joint comfort, with dramatic improvements noted after 2-4 weeks of treatment. Improvements continued to 6 months and beyond.10

In addition to the above studies, a review was conducted in 1987 to assess the results of SAM-e supplementation in clinical trials for enhancing joint Mobility and function. Over 22,000 individuals had participated in the clinical trials that were the subject of this review. The author concluded from his analysis that SAM-e was shown to be highly efficacious, rivaling or surpassing the effectiveness of other treatments, and also possessing a high level of safety.11 Because of this, SAM-e may be the treatment of choice for enhancing joint function.

Supports Liver Health and Detoxification*

SAM-e supplementation can have profound benefits on liver function. These benefits center around its function as the major methyl donor in the liver, as well as its lipotropic activity. SAM-e also enhances the production of the antioxidant glutathione.

A number of trials have been conducted showing the ability of SAM-e to support liver detoxification functions and enhance liver health in individuals susceptible to toxin-induced liver compromise. SAM-e has the ability to normalize liver function by increasing the activity of enzymes needed to upregulate liver detoxification. These effects are comprehensive and rapid. Dosages used in these studies range from 600 mg to 1600 mg daily for 2 months to two years.12,13,14 In these trials, significant benefits of SAM-e supplementation were seen over placebo.

Safety

SAM-e has an excellent safety profile and is considered well-suited for long term use based on multiple clinical trials. Individuals diagnosed with manic depression should avoid SAM-e supplementation, as it may aggravate the manic phase *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1. Agnoli A, Andreoli V, Casacchia M, Cerbo R. Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms. J Psychiatr Res. 1976;13(1):43-54.

2. De Leo D. S-adenosylmethionine as an antidepressant. Curr Ther Research. 1987;41(6):865-70.

3. Kagan BL, Sultzer DL, Rosenlicht N,Gerner RH. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990 May;147(5):591-5.

4.Salmaggi P,Bressa GM,Nicchia G,Coniglio M,La Greca P,Le Grazie C.Doubleblind, placebo-controlled study of S-adenosyl-L-methionine in depressed postmenopausal women. Psychother Psychosom. 1993;59(1):34-40.

5. Bressa GM. S-adenosyl-l-methionine (SAMe) as antidepressant: metaanalysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. 6.Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr. 2002 Nov;76(5):1158S-61S.

7. Harmand MF, Vilamitjana J,Maloche E, Duphil R, Ducassou D. Effects of Sadenosylmethionine on human articular chondrocyte differentiation. An in vitro study. Am J Med. 1987 Nov 20;83(5A):48-54.

8. Caruso I, . Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease. Am J Med. 1987 Nov 20;83(5A):66-71.

9. Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. Report of an open phase IV study with ademetionine (Gumbaral). Am J Med. 1987 Nov 20;83(5A):84-8.

10. Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med. 1987 Nov 20;83(5A):89-94.

11. di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med. 1987 Nov 20;83(5A):60-5.

12. Frezza M, et al. S-adenosylmethionine counteracts oral contraceptive hepatotoxicity in women. Am J Med Sci. 1987; 293(4):234-238.

13. Frezza M, Surrenti C, Manzillo G, Fiaccadori F, Bortolini M, Di Padova C. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology. 1990 Jul;99(1):211-5.

14. Mato JM, et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol. 1999 Jun;30(6):1081-9.



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Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...
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Date: July 27, 2005 12:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Hyaluronic Acid w/Chondroitin Sulfate - Benefits of...

Benefits

• Supports Healthy Joint Structure and Function*

Components of BioCell Collagen II including collagen type II, chondroitin sulfate and hyaluronic acid (HA) can enhance proteoglycans in the joint matrix, thereby providing support for healthy joint function and maintaining joint shock absorption and cushioning.

CHONDROITIN SULFATE

Chondroitin has been well studied for its effects on joint health. In a 1996 controlled, double-blind trial published in the Journal of Rheumatology, 146 volunteers consumed chondroitin sulfate daily for 6 months. Changes in joint function were measured according to several clinical parameters and carefully analyzed. After the first month, significant improvements were noted and maintained for three months after the subjects stopped taking the chondroitin sulfate.1 In an earlier double-blind study subjects taking chondroitin sulfate had improvements in joint function after three months of use, as determined by both objective and subjective measurements.2 In both studies, the benefits lasted for weeks after subjects stopped taking chondroitin sulfate.

In another controlled study, 192 subjects took chondroitin sulfate or a placebo daily for one year. At the end of the trial, chondroitin sulfate maintained healthy joint cartilage thickness, while those on placebo had decreased cartilage. Improvements in joint function also occurred. The researchers reported that chondroitin exerted a clear chondroprotective effect.3

COLLAGEN TYPE II

A number of studies have also been conducted on the administration of collagen type II to individuals that have various joint issues. Much of this research has been conducted on animal models of joint conditions while there are also studies showing the effectiveness of oral collagen type II preparations in humans for maintenance of healthy joints.

A randomized controlled trial conducted on 60 patients with joint health issues in 1993 found that oral administration of chicken collagen type II for 3 months led to a significant decrease in swollen and tender joints in this group, as compared to no measurable improvement in the placebo group. There were also no side effects seen with the treatment.4 A second multicenter, double-blind, placebo-controlled trial in 274 individuals with joint issues was published in 1998. The participants were given collagen type II orally for 24 weeks. Positive effects of the treatment were noted while no adverse effects were seen.5

A paper published in 2000 reviewed the literature to assess the role of hydrolyzed collagen in joint and bone health. It was found that hydrolyzed collagen when administered orally was able to support joint health in most of the trials reviewed while the author concluded that, “Its high level of safety makes it attractive as an agent for long-term use.”6

HYALURONIC ACID (HA)

Most of the literature on hyaluronic acid and joint health deals with its intra-articular use, or injections of HA directly into the joints. In this realm, there is good evidence for the effects of HA on joint function.

A study was conducted with injectable HA in individuals with TMJ (temporomandibular joint) conditions. Participants received two injections, each one week apart, or placebo injections with saline. In the HA group, the researchers found decreased clicking sounds and increased function of the joint at 1 month (90% of patients showed improvement) and 6 months (63%) of follow-up, compared to about 26% of the placebo group showing improvement at 6 months.7

A pair of researchers also conducted a literature review of the trials using HA for improving joint health that was published in 2005. Their findings indicate a positive role for HA in modifying the structure of the joint and slowing progressive deterioration of joint function and Mobility.8 Hyaluronic acid seems to have a natural affinity for joint tissue, and is therefore able to help support healthy joint structure and function.

• SuSupports Healthy Joint Structure and Function*

Hyaluronic Acid and Collagen are both vital components of skin tissue. Both compounds are known to decline with aging. Collagen is a vital structural component of the skin. It is also one of the most important substances required for proper skin barrier function and health. Collagen, as a major component of the connective tissue, provides structural support, increasing elasticity and tone of the skin.

In 1994, researchers performed comparative measurements of hyaluronic acid levels in the skin of young and elderly individuals. The researchers had hypothesized that a major reason for the aged appearance of skin in the elderly is a reduction of hyaluronic acid levels. What they found using their methods is that there is a progressive reduction in the number of hyaluronic acid granules in human skin with age, until a complete absence of these granules was seen in individuals 60 years or older. These variations in HA levels with age could, according to the researchers, account for the decreased turgidity, wrinkled appearance and altered elasticity of skin tissue.9 Further research was needed to determine the effect of exogenously administered HA on the suppleness of human skin.

In a laboratory study conducted in 1998, researchers analyzed the effects of HA given to live human skin cells. Whereas the cells on their own had a low rate of renewal, hyaluronic acid added to the cells resulted in increased proliferation of skin cells in the collagen matrix. This showed that supplementing skin cells with HA caused a significant increase in the ability of cells to go through the cell cycle.10 One of the major benefits of this may be hyaluronic acid’s ability to continually renew skin tissue to help maintain a youthful appearance of the skin.

Safety

Suggested Adult Use: Take 2 capsules daily, or as directed by a health care practitioner. Take with 8-10 ounces of water, with or without food.

Scientific References

1. Morreale P, et al. Comparison of the antiinflammatory efficacy of chondroitin sulfate and diclofenac sodium in patients with knee osteoarthritis. J Rheumatol (1996) 23:1385-91.

2. Mazières B, et al. Chondroitin sulfate for the treatment of coxarthrosis and gonarthrosis. A prospective, multicenter, placebo-controlled, double blind trial with five months follow up. Rev. Rhum. Mal. Ostèoartic. 1992;59(7-8):466-472.

3. Pipitone V, et al. A multicenter, triple-blind study to evaluate galactosaminoglucuronoglycan sulfate versus placebo in patients with femorotibial gonarthritis. Current Therapeutic Research 1992 52(4):608-38.

4. Trentham DE, et al. Effects of oral administration of type II collagen on rheumatoid arthritis. Science. 1993 Sep 24; 261(5129) 1727-30.

5. Barnett ML, et al. Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum. 1998 Feb; 41(2): 290-7.

6. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease. Semin Arthritis Rheum. 2000 Oct;30(2):87-99.

7. Hepguler S, et al. The efficacy of intra-articular sodium hyaluronate in patients with reducing displaced disc of the temporomandibular joint. J Oral Rehab. 2002; 29: 80-86.

8. Goldberg VM, Buckwalter JA. Hyaluronans in the treatment of osteoarthritis of the knee: evidence for disease-modifying activity. Osteoarthritis Cartilage. 2005 Mar;13(3):216-24.

9. Ghersetich I, et al. Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol. 1994 Feb; 33(2): 119-22.

10. Greco RM, et al. Hyaluronic acid stimulates human fibroblast proliferation within a collagen matrix. J Cell Physiol. 1998 Dec; 177(3): 465-73.

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Celadrin - Benefits
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Date: July 27, 2005 11:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celadrin - Benefits

Benefits

Increased Range of Motion in Joints*

Research has shown that Celadrin can have an impact on improving the range of motion in joints. A placebo-controlled trial conducted in 2002 showed that those individuals taking a complex containing Celadrin for 2 months had a significant improvement in knee flexion (ability to bend the knee) over those taking a placebo.1 Another study conducted on Celadrin published in 2004 concluded that treatment “significantly increased physical performance (as measured by a variety of orthopedic tests)” in patients with compromised knee Mobility. The study found that the subjects given Celadrin showed improvement in their ability to climb stairs, rise from a chair and walk, along with an improved sense of balance, strength and endurance.3

Maintains Joint Comfort*

The anti-inflammatory actions of Celadrin have been demonstrated by one double-blind, placebo controlled trial that showed Celadrin, when taken orally at recommended intake levels, decreased pain scores and increased walking distance compared to the group receiving placebo. The authors theorize that Celadrin may work by down-regulating the effect of certain precursors of the body’s inflammatory response.1

Safety

Suggested Adult Use: One capsule three times daily, with or without food.

Scientific References
1. Hesslink R Jr., et al. Cetylated fatty acids improve knee function in patients with osteoarthritis. J Rheumatology 2002;8:1708-1712.

2. Anonymous. Monograph: Glucosamine sulfate. Alt Med Review 1999;4:3;193-195.

3. Kraemer WJ, et al. Effect of a cetylated fatty acid topical cream on functional Mobility and quality of life of patients with osteoarthritis. J Rheumatology 2004;4:767-74.

4. Crolle G, D'Este E. Glucosamine sulphate for the management of arthrosis: a controlled clinical evaluation. Curr Med Res Opin 1980;7:104-109.

5. Rovati LC. Clinical research in osteoarthritis: design and results of short-term and long-term trials with disease modifying drugs. Int J Tissue React 1992;14:243-51. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.

6. Bassleer C, et al. Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro. Osteoarthritis and Cartilage 1998;6:427-434. Med. 2002 Oct 14;162(18):2113-23.

7. Reginster JY, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet 2001;357:251-56.

8. Macario, J. T., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 9. Kraemer WJ, et al. Effect of acetylated fatty acid topical cream on functional Mobility and quality of life of patients with osteoarthritis. J Rheumatol.2004 Apr;31(4):767-74. 10. Kraemer WJ,et al. Acetylated fatty acid topical cream with menthol reduces pain and improves functional performance in individuals with arthritis. J Strength Cond Res.2005 May;19(2):475-80.



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SAMe - Supports Joint Comfort, Function and Mobility ...
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Date: June 06, 2005 08:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SAMe - Supports Joint Comfort, Function and Mobility ...

SAMe (S-adenosyl-L-methionine)

You’ve read about it in the media. Europeans have experienced its health benefits for two decades. Now consumers in the United States have access to a nutrient with groundbreaking potential. SAMe, a natural compound formed in our bodies from the amino acid methionine, is stirring excitement due to its wide-ranging health effects. SAMe plays a critical role in cartilage formation. Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and Mobility in the spine, hips and knees. SAMe has also been found to support a positive outlook. It affects the synthesis and activation of proteins such as mood-boosting neurotransmitters.

Cutting-Edge Nutrition

Technological advances have made possible the production of stable, bioavailable forms of a natural nutrient with broad-range potential. Source Naturals now offers you the fruits of that technology.

A Multipurpose Nutrient

SAMe, or S-adenosyl L-methionine, is formed when our bodies combine the amino acid L-methionine with ATP, the primary energy-carrying molecule in our cells. SAMe is a multipurpose nutrient, which is present in every living cell. Because SAMe is involved in so many vital processes, it is important that our bodies produce sufficient SAMe. However, SAMe levels tend to decline with age, and also can be affected by dietary imbalances. To produce adequate amounts, we need to consume not only methionine-containing protein foods, but also foods rich in vitamins B-6, B-12 and folic acid, which are needed to ensure the synthesis of SAMe. SAMe also is a highly unstable molecule. A lot of scientific research was needed to make it available as a supplement. Source Naturals has studied the research and offers this vital nutrient in a form your body can use.

Methylation is the Key

SAMe is known as a “methyl donor.” This means that it works by giving up a piece of itself (a methyl group consisting of one carbon and three hydrogen atoms) to other molecules. This methylation process affects the synthesis, activation and metabolism of various hormones, neurotransmitters, phospholipids, nucleic acids, proteins and other biological molecules. Methylation plays a part in many critical functions, including the maintenance of cell membranes, the removal of toxic substances from the body and the production of mood-boosting neurotransmitters such as dopamine and serotonin.

Effective Joint Support

SAMe has been used in Europe for two decades for joint support. Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and Mobility in the spine, hips and knees. SAMe is important in a process called transsulfuration. The breakdown of SAMe generates sulfate groups that help maintain joint cartilage. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage.

Promotes Mental Well-Being

Studies also show that SAMe helps support a positive outlook. Although the mechanism by which SAMe promotes mental well-being is not known, we do know it is able to cross the blood-brain barrier, where it affects the production of mood-boosting neurotransmitters.

Clinically Researched Potency

Source Naturals SAME is offered in the clinically researched potency of 400 mg per suggested daily use (two tablets). The tablets are enteric coated and blister packed to prevent breakdown and inactivation of ingredients. Source Naturals SAME is available in 20-tablet boxes.

References:
Berger, R. et al. 1987. “A New Medical Approach....” The American Journal of Medicine; 83(5A): 84-88. Carney, MWP et al. 1987. “S-adenosylmethionine....” The American Journal of Medicine; 83(5A): 104-106. Konig, B. 1987. “A long-term (two years) clinical trial of oral S-adenosylmethionine....” The American Journal of Medicine; 83(5A): 89-94. Stramentinoli, G. 1987. “Pharmacological aspects of S-adenosylmethionine.” The American Journal of Medicine; 83(5A):35-42



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Joint Response and Ultra Joint Response
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Date: June 02, 2005 01:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Joint Response and Ultra Joint Response

Many people are unaware of the multiple body systems involved with joint health. Source Naturals ULTRA JOINT RESPONSE™ is a Bio-Aligned Formula™ that goes deep to bring alignment to these multiple systems. It features structural building blocks, tissue production cofactors, and ingredients that aid the body’s mechanisms for soothing relief and antioxidant defense.

Joint Support Formulations

You can use ULTRA JOINT RESPONSE alone or as the core of your healthy joints program, complementing it with additional potencies and ingredients. These include: GLUCOSAMINE CHONDROITIN WITH MSM™, MSM Cream, SAME, CM COMPLEX™ Cetyl Myristoleate, and BROMELAIN. For muscle discomfort and fatigue, Source Naturals also offers you FIBRO-RESPONSE™ Bio-Aligned Formula.

ULTRA JOINT RESPONSE™: BIO-ALIGNED FORMULA

ULTRA JOINT RESPONSE uses scientifically researched ingredients and nutritive co-factors for a comprehensive approach to soothing, lubricating, rebuilding and aligning connective tissue, joints, tendons and ligaments. MSM dietary sulfur, glucosamine and sea cucumber provide structural building blocks that are necessary to help maintain the integrity of joints and connective tissue. Vitamins A, B-6 and C, zinc, manganese, and copper act as co-factors or parts of enzymes that play a role in connective tissue formation and maintenance. Various soothing herbs, rich in polysaccharides and other constituents, assist the body’s natural mechanisms for soothing relief. Finally, N-acetyl cysteine, grape seed, beta carotene, vitamin C, zinc, selenium, horse chestnut, turmeric, and quercetin support the body’s natural antioxidant response, thereby helping maintain the health and integrity of joints and tissues (specifically cell membranes).

GLUCOSAMINE CHONDROITIN WITH MSM: HOT RESEARCHED INGREDIENTS

For added support, Source Naturals offers you a formula that combines higher potencies of the most popular joint nutrients: glucosamine sulfate, chondroitin sulfate and MSM. GLUCOSAMINE CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and glucosamine shown in recent research to support healthy joints—along with MSM, vitamin C, and molybdenum, for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement.

FIBRO-RESPONSE: BIO-ALIGNED FORMULA Dealing with the muscle discomfort that affects millions in our society requires more than alleviating fatigue. FIBRO-RESPONSE influences specific body systems and tissues involved in joint health and muscular metabolism. Malic acid and magnesium, supplied in the same amounts used in recent research, help support muscular energy production, along with coenzyme Q10, lipoic acid and B-complex vitamins. MSM, copper, manganese, molybdenum, zinc, vitamin C, and beta carotene support healthy connective tissue, which is essential for proper joint and muscle function. Key ingredients, including N-acetyl cysteine and silymarin aid the liver in eliminating toxic waste from blood and tissues. Ingredients including lipoic acid, selenium, N-acetyl cysteine, and coenzyme Q10 support antioxidant defense, thereby helping to maintain tissue integrity. And ginkgo and GABA are among the ingredients that support clear focus and stress reduction.

LIFESTYLE TIPS FOR HEALTHY JOINTS: A STRATEGY FOR WELLNESSSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, and eliminate polyunsaturated and hydrogenated oils. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: In addition to the formulas described above, Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAMe, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and Mobility; and CM COMPLEX™ Cetyl Myristoleate, a fatty acid ester shown in recent research to reduce joint discomfort.



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Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort
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Date: June 02, 2005 12:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort

It happens. You reach for something and feel a sudden discomfort. Your joints and muscles may feel tender from overuse. Inside, your cellular systems are out of alignment, resulting in lessened Mobility. Source Naturals understands how difficult joint discomfort can be to live with. We are deeply committed to developing well-researched formulas that address the root cause of joint distress. Our Bio-Aligned Formulas™ bring alignment to multiple interdependent body systems. Only this type of indepth formulation can provide the long-term relief you are looking for. Regain your comfort with Source Naturals INFLAMA-REST. Unlike many products that contain just a few ingredients to offer temporary relief, INFLAMA-REST is a Bio-Aligned Formula™, scientifically designed to address aches. INFLAMA-REST goes deep to the underlying cause of joint discomfort. These systems include: inhibition of pathways involved in joint discomfort, joint and muscle function, DNA protection and antioxidant defense.

Addressing Joint Comfort on a Deep Cellular Level

Discomfort can come from many places. From your head to your toes there are many tissues that can become uncomfortable from everyday use. Joint discomfort starts when stress, such as tissue damage, causes an imbalance of the biochemical pathways on a deep cellular level. The body has its own “innate intelligence” encompassing more than just the thoughts in the brain. It consists of ongoing and complex chemical reactions regulated by a wide variety of enzymes and chemical messengers. These reactions can sometimes get out of balance – but you can control and inhibit key body chemicals that would otherwise lead to cellular irritation. For example, certain types of prostaglandins that regulate normal physiological functions such as blood flow, are maintained at low levels in all our cells under everyday conditions. In response to stress, a message is sent to the outer membranes of certain cells to convert their fatty acids into arachidonic acid, the raw material for prostaglandins. This stress also directs cells to produce Cyclooxygenase enzyme- 2 or COX-2. This enzyme converts arachidonic acid into Prostaglandin E2, a particular type of prostaglandin specifically responsible for irritation on a cellular level. The result: joint discomfort. But that doesn’t have to happen. By supporting inhibition of the culprit COX-2, you can decrease Prostaglandin E2 production to bring your joint tissues back into a healthy and comfortable balance.

Support COX-2 Inhibition

INFLAMA-REST includes herbs that support inhibition of COX-2 in a variety of pathways. Ginger, turmeric and green tea all support direct COX-2 inhibition. But there are other places in our biochemical communication system where COX-2 production can be inhibited. Two additional factors that lead to COX-2 production are nitric oxide and the enzyme that produces it, nitric oxide synthase (iNOS). Nitric oxide is a free radical associated with cell growth and regeneration, blood vessel elasticity and COX-2 enzyme production. Resveratrol, rosemary and turmeric support iNOS inhibition, thus inhibiting your body’s over-production of nitric oxide and the COX-2 enzyme. A related irritation factor is also one of the latest scientific discoveries in cellular health - Nuclear Factor kappa-B (NF-kappa-B). NF-kappa-B works at the DNA level – at the blueprints of cells. When activated, this factor controls the genes that regulate cell growth, differentiation and regeneration. And blocking this factor is also associated with inhibition of both COX-2 and iNOS enzymes. Stinging nettle, milk thistle and Chinese Skullcap all block unhealthy NF-kappa-B activation in your body and thereby help support COX-2 inhibition.

Cytokine Inhibition

Compounds called cytokines, or interleukins, can also stimulate biochemical pathways leading to joint discomfort. Cytokines are chemical messengers produced by the immune system to regulate defensive activity when they are stimulated. For example, cytokines are released by macrophages in response to stimuli such as tissue damage. This results in rapid escalation and amplification of cell number and response. Constant stress can shift this system out of balance, resulting in tissue discomfort. Bringing these compounds back into balance can preserve your short-term comfort and longterm health. INFLAMA-REST contains curcumin from the spice turmeric. Curcumin assists the body’s inhibition of cytokine activity to support reduced cellular irritation. And Bioperine®, which is derived from black peppercorns, is added to assist curcumin assimilation.

Stress Response: Joints and Muscle Support

Inhibition of chemical messengers involved in joint discomfort is just part of a Bio-Aligned strategy for relieving discomfort. Research has shown that emotional stress, particularly long-term, can directly affect the body and set in motion mechanisms that cause physical discomfort. Ashwaganda and Chinese Skullcap (S. baicalensis) are herbs that help modulate the body’s response to stress and may help ease aches and discomfort. Boswellia, ginger, quercetin, milk thistle, feverfew, Oregon grape root and bromelain (an enzyme found in pineapples) provide additional soothing relief to your cells and tissues. Essential nutrients are also vital to maintaining your joint comfort. The tocotrienol forms of vitamin E, along with selenium, protect cell membranes from lipid-based free radicals. Magnesium aids energy metabolism in muscles and can reduce tenderness as well as muscle spasms. Zinc is essential for normal cellular repair mechanisms such as wound healing and is important for the growth and maintenance of connective tissue. And manganese works to protect cells from oxidation and to build healthy connective tissue as well, an essential component of healthy joints and muscles.

Protecting Your DNA

To reduce cellular irritation, you need to protect the DNA in your cells. DNA is the blueprint for all of the molecules in the body. If your DNA is altered or damaged, then needed molecules may not be produced, leading to short-term and eventually long-term damage. Curcumin, from turmeric, has been shown in in-vitro studies to protect DNA against strand breakage. Quercetin has also been shown to directly protect DNA against strand breakage and base oxidation from free radicals and damaging chemicals, according to recent in-vitro research.

Providing Powerful Antioxidant Cellular Protection

Antioxidants are selfless bodyguards of your cells. They donate their own electrons to stabilize free radicals in your body. Thus, antioxidants absorb the damage that would have been done to your tissues. Some regulatory chemicals, such as Nitric oxide, are powerful free radicals and oxidants. Oxidants also activate NF-kappa-B. Tissues, lipids, proteins and DNA are extremely sensitive to oxidation. Quercetin, milk thistle, turmeric, ginger, rosemary, vitamin E and resveratrol are all antioxidants that help modulate the activity of these compounds as well as protect cells and tissues from damage. Plus, Superoxide Dismutase (SOD), one of the most important enzyme antioxidants found in your body, has been added in a new cutting-edge form. The vegetarian SOD used in INFLAMA-REST is attached to Gliadin, a wheat protein, that has demonstrated significantly better absorption than SOD alone.

Six Lifestyle Strategies for Fewer Aches


1. Try Yoga or Tai Chi. Low-impact exercise based on slow fluid movements can improve Mobility and flexibility as well as greatly reduce stress.
2. Get in the pool. Exercising while in the pool reduces strain on the joints in addition to strengthening muscles.
3. Maintain a healthy weight. Excess weight adds pressure to joints and connective tissues.
4. Eat omega-3s. Omega-3 fatty acids found in salmon, flax seeds, or in supplement form support healthy joints and tissues.
5. Stay hydrated. Water is the basis of lubrication in connective tissues such as joints and skin and also supports detoxification.
6. Supplement with glucosamine, chondroitin, MSM and hyaluronic acid. These supplements can help maintain healthy connective tissues. Source Naturals is pleased to partner with your local health food store to provide INFLAMA-REST as a comprehensive Bio- Aligned Formula for relieving joint discomfort by protecting, nourishing and soothing irritated cells. Make INFLAMA-REST part of your health plan to live without joint discomfort.

  • INFLAMA-REST is a Bio-Aligned Formula™ Multi-System Support for Joint Comfort

    Inhibition of COX-2: Turmeric, Ginger, Chinese Skullcap, Green Tea, Resveratrol, Boswellia, Silymarin, White Willow Inhibition of Cytokine Turmeric, Stinging Nettle, Feverfew Inhibition of Rosemary, Green Tea, Resveratrol, Turmeric, Quercetin, Chinese Skullcap NF-kappa-B Activation Silymarin, Chinese Skullcap, Stinging Nettle, Rosemary, Resveratrol Stress Response: Ashwaganda, Magnesium, Chinese Skullcap, Oregon Grape, Feverfew, White Willow DNA Protection Turmeric, Quercetin, Rosemary Antioxidant Defense Silymarin, SOD Gliadin, Turmeric, Rosemary, Tocotrienols, Resveratrol, Ginger, Selenium, Manganese, Zinc Prostaglandin & Leukotrine Synthesis Joint & Muscle Support Inhibition of Nitric Oxide Synthesis Production



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    GlucosaMend™ Tissue/Joint Repair Complex
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    Date: June 02, 2005 11:19 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GlucosaMend™ Tissue/Joint Repair Complex

    GlucosaMend

    More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense.

    Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance.

    Musculoskeletal System—Structural Building Blocks

    Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains glucosamine sulfate, N-acetyl glucosamine, proline and lysine.

    Musculoskeletal System—Tissue Production Cofactors

    Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors.

    Soothing Relief Mechanisms

    Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6.

    Antioxidant Defense

    The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides grape seed extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals.

    Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM

    Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and Mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage.

    Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E

    References
    Bhavan’s, B. H. Selected Medicinal Plants of India (A Monograph of Identity, Safety, and Clinical Usage) Bombay: Chemexcil, 1992. Dore-Duffy, P., et al. (1990, Nov-Dec.). “Zinc profiles...” Clinical and Experimental Rheumatology 8.6: 541-46. Ellis, J. M. (1985, Winter). “Vitamin B6 deficiency and rheumatism.” Anabolism. Lakshmi, R., et al. (1991, Oct-Dec.). “Effect of riboflavin or pyridoxine deficiency on inflammatory response.” Indian Journal of Biochemistry and Biophysics 28.5-6: 481-84. Leibovitz, B., (1991). Nutrition Update 5.3: 5. Levine, M. (1986). “New concepts in the biology and biochemistry of ascorbic acid.” New England Journal of Medicine 314: 892-902. Pavelka, K, Gatterova, J., Olejarova, M, Machacek, S., Giacovelli, G., Rovati, L.C., (2002). “Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis: A 3-Year, Randomized, Placebo-Controlled, Double-Blind Study. Arch Intern Med, 2002 October 14; 162(18):2113-23. Roubenoff, R., et al. (1995, Jan.). “Abnormal vitamin B6 status...” Arthritis and Rheumatism 38.1: 105-9. Shampe, P., and R. Harvey. Lippincotts Illustrated Reviews: Biochemistry. Philadelphia: J. B. Lippincott Company, 1987. Tarp, U., et al. (1985). Scandanavian Journal of Rheumatology 14.2: 97-101. Volpi, N., (2002). “Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers,” 2002 Oct; 10(10):768.



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    Arcticpure EFA and EPA Fish Oil supplement ...
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    Date: May 31, 2005 05:05 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Arcticpure EFA and EPA Fish Oil supplement ...

    Essential fatty acids are crucial for health—as much so as daily vitamins and minerals. And fish oil is one of the best sources of these nutrients. Now Source Naturals offers you three premium fish oil concentrates. ARCTICPURE DHA supplies the essential brain nutrient DHA. ARCTICPURE EPA is ideal for cardiovascular support and joint Mobility. ARCTICPURE EFA contains a blend of healthful fatty acids. All ARCTICPURE products contain fish oils from the cleanest and coldest body of water, the Arctic Sea. A series of distillation processes concentrates and extracts beneficial fatty acids, while guaranteeing the absence of heavy metals and PCB’s.

    EFA’s: Healthy Fats

    Essential fatty acids (EFA’s) support an amazing variety of cellular processes. They maintain cell wall and membrane integrity, generate energy, produce hormones and support brain, nerve, and eye function. Yet too many people today eat diets that are high in saturated or hydrogenated fats, but low in healthy fats—essential fatty acids. ARCTICPURE softgels are an excellent source of EFA’s, including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), gamma linolenic acid (GLA), and alpha linolenic acid (ALA). ArcticPure DHA™ DHA is an omega-3 long chain fatty acid that is the primary building block of the brain and retina of the eye. The brain is 60% fat, and DHA is the most abundant fatty acid in the brain, comprising 25-35%. DHA is found in even greater concentrations—50-60%—in the retina. DHA is critical for infant development, especially the rapid cerebral and eye development that occurs during pregnancy and in the first few months after birth. It is therefore an important nutrient for pregnant women and nursing mothers. DHA also has been associated with optimal memory function, visual acuity, and maintaining a positive mental state. It is an integral component of all membranes with electrical activity, including the cells in our brain and nervous system. ARCTICPURE DHA contains 50% DHA, or 250 mg, in each softgel.

    ARCTICPURE EPA™

    EPA is another omega-3 fatty acid, which has been associated with many potential health benefits. Epidemiological and animal studies have shown that EPA can support a healthy cardiovascular system. It is important for healthy skin and is a precursor of prostaglandins, thromboxanes and leukotrienes. These chemical mediators help regulate a variety of physiological processes, including blood pressure and blood clotting. ARCTICPURE EPA supplies 45% (450 mg) of EPA—one of the highest concentrations available.

    ARCTICPURE EFA™

    ARCTICPURE EFA is a source of EPA, DHA, and also GLA (gamma-linolenic acid) from borage oil, and additional omega-3 fatty acids including ALA. GLA is an essential polyunsaturated fatty acid. It is used by most cells to produce the soothing, intracellular, hormonelike messengers known as series 1 prostaglandins (PGE1), which help maintain the balance of many functions in the body. GLA supports the immune system and helps maintain healthy skin and circulation. This essential nutrient is incorporated into our cell membranes, where it helps to maintain fluidity and permeability.

    Stabilized for Freshness

    ARCTICPURE oils are enhanced with antioxidants such as lecithin, ascorbyl palmitate, vitamin E and rosemary oil, for extended shelf life. They also contain natural fruit flavors, so there is no fishy taste! ARCTICPURE softgels are pleasing to both children and adults.



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    Under-Reported (and Underappreciated) Cholesterol control.
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    Date: May 12, 2005 10:00 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Under-Reported (and Underappreciated) Cholesterol control.

    Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Control

    by Richard Conant, L.Ac., C.N.

    Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.

    The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.

    Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.

    The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)

    Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.

    Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.

    How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look.

    Gugulipid

    In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.

    Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."

    Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.

    Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.

    Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.

    Pantethine

    Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6

    Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.

    Niacin

    When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.

    There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12

    Tocotrienols

    We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.

    Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.

    The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."

    It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.

    References

    1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.

    2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.

    3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.

    4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.

    5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.

    6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.

    7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.

    8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.

    9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.

    10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.

    11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15.

    12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3.

    13. Serbinova, E., et. al. Free radical recycling and intramembrane Mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275.

    14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.

    Control Cholesterol with the following Supplements

  • Policosanol -- Reduces Production of Cholesterol by the Liver
  • Red Yeast Rice -- Reduces production of cholesterol like pharmaceutical Statins on the market today
  • Sytrinol -- Lowers Cholesterol by reducing production of cholesterol in the body like Statins on the market today
  • Fiber -- Helps elimate waste and reduce cholesterol


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    Celadrin® Complex with Glucosamine.
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    Date: May 12, 2005 09:31 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Celadrin® Complex with Glucosamine.

    DOCTOR’S BEST INTRODUCES Celadrin® Complex with Glucosamine. A potent new joint soothing formula now available from Doctor’s Best!

    SAN CLEMENTE, Calif., January 2005 –– Doctor’s Best has introduced Celadrin ® Complex with Glucosamine into its dietary supplement line. Ken Halvorsrude, president of Doctor’s Best, made the announcement.

    Celadrin ® is a special blend of fatty acids that have been shown in double-blind, placebo-controlled trials to support joints and improve Mobility. Fatty acids have been shown to induce changes in cell membranes and their responsiveness to immune factors, which often result in painful side effects. The special fatty acids found in Celadrin ® have also been shown to control and reduce the production of immune factors which can have a negative impact on the body.

    Current studies show that Celadrin ® works much more effectively than the essential fatty acids, such as EPA and DHA from fish oils,” Halvorsrude says, “plus it provides continuous lubrication to joints, and helps prevent tissue stiffening.”

    The results of a double-blind, placebo-controlled trial found that Celadrin ®, when taken orally, helped improve joint and Mobility problems. Sixty-four participants between the ages of 37 to 77 were given Celadrin ® capsules. They were evaluated at the beginning, at 30 days and at the end of the 68 day study. When compared to the placebo group, Celadrin ® participants had more flexibility, and were able to walk longer distances than the placebo group.

    Glucosamine, which has been shown in clinical studies to increase range of motion, also assists in rebuilding cartilage. When used in combination with Celadrin ®, glucosamine works even more efficiently at building cartilage and providing rapid joint cushioning.

    “For these reasons, “ Halvorsrude says, “we feel that Celadrin® Complex with Glucosamine will be able to bring relief to many people suffering with joint problems.”

    Founded in 1990 by supplement industry veteran Halvorsrude and a wholistic physician, San Clemente-based Doctor’s Best, Inc. manufactures and distributes dietary supplements throughout the U.S. and overseas. Doctor’s Best is known for high-quality products that are based on sound research in the field of nutritional science. For more information:

    Celadrin Complex with Glucosamine


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