Search Term: " Bioactive "
Daily consumption of tea may protect the elderly from cognitive decline, study suggests
March 23, 2017 06:44 AM
A recent study of almost a thousand Chinese seniors aged 55 and over strongly suggests that drinking tea daily can help reduce the risk of cognitive decline by at least fifty percent, and as much as eighty-six percent in some. Starting in 2003, the seniors' tea drinking habits were tracked for two full years. Then their cognitive function was assessed every two years, ending in 2010. Possible confounding factors were controlled carefully. At this point in time, scientists believe this finding is due the Bioactive compounds in tea.
Daily consumption of tea protects the elderly from cognitive decline
March 20, 2017 03:44 PM
The daily consumption of tea protects elderly people from cognitive decline. It reduces the decline by 50 percent and as much as 86 percent for people who have a genetic risk for Alzheimer's disease. New research has come to this conclusion. The saying is that a cup of tea a day can help keep dementia away.
""A cup of tea a day can keep dementia away...""
Remarkable health benefits of moringa
February 03, 2017 10:59 AM
Moringa is a relatively large tree that is native to North India. It goes by a variety of names, such as drumstick tree, horse radish tree, or ben oil tree. How amazing! Almost all parts of the tree are edible and can be used as ingredients in traditional/herbal medicines. The leaves and pods are commonly eaten in parts of India and Africa. Moringa which is botanically known as Moringa oleifera, is a popular plant known for its rich antioxidant property and its several Bioactive content of plant compounds.
"Ever heard about the mystical miracle plant or the plant referred to as ‘the tree of life’?"
Want to Eat Better? Just Eat More Color
January 21, 2017 12:59 PM
I've heard of eating the rainbow. This talks more about that. Eating a wide variety of color when it comes to fruits and veggies helps you get the proper balance of nutrients. The different colors mean different vitamins and minerals are present in the food. A varied diet is both healthful and more interesting so no one gets tired of the same thing.
"Produce companies rarely include information on which phytochemicals are in their foods, making it even more important you know nature's color coding system."
What Is Lactoferon And How Can It Boost Your Health?
August 06, 2014 09:01 AM
What is lactoferrin
Lactoferrin is a Bioactive milk protein, especially concentrated in both human and ox-like colostrum and has been sold for a long time as a wholesome supplement with, hostile to bacterial, against contagious, hostile to viral and safe fortifying exercises. However the work demonstrating its bone building properties shows significantly more prominent potential.
Bad tempered Bowel Syndrome (IBS) is the most well-known gastrointestinal issue in the United States, influencing 1 out of 5 individuals. Indeed, with a large number of individuals looking for help for this, the reasons are still not well caught on. Numerous look for regular course, when conventional techniques don't bring the help they require. Analysts accept a combo of physical and mental well being issues can prompt the entrails getting to be harmed, or delicate to specific stressors. This can prompt an issue with the data pathway between the cerebrum and the gut, bringing about modifying intestinal capacity.
Side effects of lactoferrin
Side effects could be a consequence of a contaminating or disturbance in the stomach and insides from microorganisms or other destructive creatures. One study demonstrated that individuals who had an episode of gastroenteritis were ten times more inclined to create touchy inside disorder. An alternate condition, called small digestive tract bacterial excess, is truly regular in individuals with IBS. An excess or change in the kind of microorganisms in the small digestive tract causes aggravation and indications of loose bowels, over abundance gas, weight reduction, and dietary lacks. Some gastrointestinal manifestations could be because of the abundance of yeast (candida). Intestinal candidiasis can result in indications of bloating, gas, the runs, blockage, and cramping, alongside exhaustion.
Lactoferrin helps the side effects by:
1. Tying to free iron drifting around. This is essential on the grounds that most microbes and candida need iron to develop. Free iron meddles with our resistant cell work, so this viably starves the destructive life forms while keeping our invulnerable frameworks solid.
2. Entering the microbes or candida and harming their phone layer. This will either murder them straightforwardly, or it meddle with their vitality and debilitate them.
3. Keeping candida from adhering to the coating of the digestive tract and uprooting it once it is appended.
4. Repressing the activity of cytokines in the gastrointestinal tract. Cytokines are proteins found in the body that cause aggravation.
5. Sustaining the digestive tract with probiotic properties, which additionally help with GI well being. Probiotics sustain the well disposed microbes that live in your digestive tract. An equalization of great to unsafe microscopic organisms is required to avert gastrointestinal manifestations
Manufactured prescription drugs applied for the treating Ostepenai or perhaps Osteoporosis can certainly simply just carry out 1 or perhaps one other these projects. Bisphosphonates Actonel, Boniva, Fosamax in addition to Calcitonin Calcimar, Cibacalcin, Calsynar, Miacalcin, Osteocalcin in addition to Salmonine modest the particular evacuation connected with old bone tissue by means of restraining the particular action connected with osteoclasts. These kinds of prescription drugs carry out nothing at all to help secure osteoclasts to produce brand new bone tissue progress. Raloxifene Evista in addition to Strontium ranlelate Protelos invigorates the particular progress connected with brand new bone tissue yet never restrain the job connected with osteoclasts of their operate connected with evacuating old bone tissue. So this overdue study displaying a new compound that could carry out both projects is actually quite energizing. To a new significant component of most of these prescription drugs get understandably real allergic reactions that will block their employment by means of a lot of folks.
Lactoferon has been indicated to be a characteristic solution for IBS. It ensures the coating of your gastrointestinal tract, help your safe framework, and support in destroying living beings that can result in manifestations. It has been named by the FDA as GRAS (for the most part perceived as sheltered) for the whole populace, even the individuals who are susceptible to grain and dairy
May 05, 2014 07:40 PM
Obese and overweight
With busy schedules day in and day out, refined foods and drinks have become the order of the day and this has led to a higher percentage of people who are obese and overweight. People have realized how this is hurting them and are very concerned about their health and are taking keen interest in how the body works and what it needs to remain healthy and in good shape. Most body processes are driven by hormones, which trigger the necessary reactions.
The body usually produces these hormones but at times, they need external boosting through intake of certain foods or medication. The T3 thyroid hormone is very important as it is responsible for stimulation of metabolism which if one is trying to lose weight is very important. Most people take thyroid drugs to increase this hormone level but a better and natural way is by using guggul extract, which does not have side effects like insomnia, jitters and heart palpitations.
What is a guggul extract and its benefits
Guggul extract is yellowish in color and it comes from guggul (gum guggul) which is a resin that comes from the mukul mirth tree. It possesses Bioactive compounds from its sterols. Guggul has been used to treat obesity, acne, inflammation and hypolidemia. Guggul works by converting T4 into T3 triiodothyronine, which is more active in speeding up metabolism. The conversion increases the amount of T3 in the blood stream. The sterols in the extract also boost thyroid stimulating hormone production, which is more direct.
This extract is best used by lose on fat loss diets as it helps maintain high levels of active thyroid which in turn helps in faster burning of the body fat. Remember dieters usually have low calorie intake and the body is designed to slow down metabolism when there is slow food intake so guggul helps crank it up.
Serrapeptidase: Natural NSAID
March 27, 2012 03:26 PM
Serrapeptase, also known as Serratia peptidase is a proteolytic (protein-splitting) Bioactive enzyme found in the intestines of the silk worm. This silk-worm enzyme is widely used in Europe and Japan in clinical therapy for relieving pain and inflammation. When the silk worm leaves the cocoon, it regurgitates the serrapeptase in to create a hole in the cocoon for its escape. It was soon discovered that serrapeptase enzyme has a unique property to dissolve dead material consisting protein without even harming the living tissue. This property of dissolving dead tissue can be used in treating many health conditions.
How Serrapeptase work?
Protein is the main component of most of the fibrous materials in the body. Once these fibrous materials out-live their purpose or are over-grown, they start causing serious disease conditions involving fibrosis. Fibrosis is an abnormal thickening and scarring of connective tissue caused by infection, injury, surgery or lack of oxygen. Serrapeptase works as an anti-fibrotic and helps in relieving the conditions in connective tissue scarring and thickening has occurred.
Health Benefits of Serrapeptase:
This proteolytic enzyme is considered an alternative to NSAIDS (Non Steroidal Anti-Inflammatory Drugs) that are used to treat osteoarthritis, rheumatoid arthritis and other inflammatory conditions. Serrapeptase has been used to treat fibromyalgia, colitis, Inflammatory Bowel Diseases, varicose veins, ovarian cysts, ear and throat infections, enlarged prostate and postoperative inflammation. Studies have shown its effective results in prevention and removal of arterial plaque.
Serrapeptase in relieving Pain:
Pain and Inflammation Reduction:
Serrapeptase is a great anti-inflammatory and analgesic agent. It reduces the inflammation and gives relief from the pain. It works by blocking the release of pain inducing amines from the inflamed tissues. Due to its pain relieving and anti-inflammatory properties, serrapeptase is used in treatment as an alternative to NSAIDS. This enzyme gives relief from mild to moderate pain like headache and backaches. Hence it is used all the inflammatory conditions such as colitis, sinusitis, arthritis and many more.
Serrapeptidase has an anti-fibrotic and fibrinolytic action that prevents and treats the accumulation of plaque in the arteries. Plaque is the accumulated deposits of cholesterol, fatty substances, cellular waste products, fibrin and calcium. Excessive plaque formation impairs the normal blood flow and cause partial or complete blockage, which also results in arteriosclerosis. Serrapeptidase helps to prevent build-up of plaque in the body. Due to its fibrinolytic action, it also helps in dissolving of proteins and breaking down atherosclerotic plaques. The dissolved deposits are eliminated from the body.
Hence, serrapeptidase prevents coronary artery diseases and improves cardiovascular health.
Due to its anti-inflammatory and mucus dissolving properties, Serrapeptidase is very beneficial for chronic sinusitis sufferers. Serrapeptidase helps in thinning and expelling the thickened mucus secretion present in nasal cavities of sinusitis sufferer.
Serrapeptidase helps in reducing the recovery time in any injuries, wounds or surgery. It promotes healing in post-operative wounds by reducing the inflammation and pain.
Serrapeptidase is available in the form of supplements. If you are taking NSAIDS for any healthy condition, substitute it with serrapeptidase supplement
Chaste Berry a Women Herb
February 08, 2012 11:51 AM
Other names of Chaste Berry- Monk's pepper, Chaste-tree Berry
Chaste Berry is the fruit found on Chaste tree which is botanically known as Vitex. Chaste tree is a decidous tree that grows in a well-drained, acidic soil in full sun. Vitus agnus castus or Chaste Berry is a native to the Mediterranean and Central Asia but now is grown throughout the world. The tree belongs to Verbanaceae family and can grow to a height of 22 feet. It was traditionally used by men in ancient Greece and Rome to reduce sexual desire, treat menstrual disorders and other hormonal problems and as an anti-microbial agent against infections. It is also known as 'Women's Herb' as it regulates hormonal imbalances and promotes women reproductive health. Aside from its medicinal use, it was used as a peppery condiment. Some of the constituents included in Chaste Berry fruit are flavonoids (casticin, orientin, isovitexin, kaemferol), glycosides (aucubin and agnuside) and essential oils (linalol, sabinene, pinene and limonene). These phytohormone compounds help in regulating the female hormones production and normalising testosterone and progesterone activity.
Effects of Chaste Berry:
ChasteBerry controls and regulates overall female reproductive system.
1. It helps to manage Pre-Menstrual Syndrome: Pre-Menstrual Syndrome is associated with several uncomfortable symptoms, ranging from mood swings to fatigue and hot flushes. Chaste Berry is known to be rich in progesterone that helps to ease out the disturbing symptoms of Pre-Menstrual Syndrome.
2. It helps to normalize menstrual irregulaties: Imbalance in prolactin levels in the body can lead to various complications in women such as amenorrhoea (absence of periods), breast tenderness and reduced milk production in lactating mothers. Chaste Berry balances natural production of prolactin hormone in the body and effectively treats menstrual irregularities and other symptoms such as tenderness of breast and reduced milk secretion.
3. It treats menopausal discomforts: Some women experience dicomfort and other menopausal symptoms that affect their daily routine life. The hormone regulating properties of Chaste Berry help in easing menopausal symptoms such as mood swings and hot flushes and several other physical symptoms associated with hormone deficiency during menopause.
4. It improves overall female reproductive health: Chasteberry has been found to be effective in treating fibroid cysts especially of smooth muscle. It also reduces heavy bleeding associated with perimenopause.
5. It helps in treating Hormonal acne: Hormonal acne are due to imbalance in androgen hormone levels. Increased androgen levels in the body leads to excessive sebum production that causes acne. This wonder herb regulates the androgen levels in the body and thereby helps in treating moderate and light acne. Another way in which this herb prevents acne formation is its anti-bacterial property. The Bioactive essential oils present in Chasteberry have anti-bacterial properties that prevent the survival of bacteria. Chaste Berry contains linoleic fatty acid which is responsible for regulating sebum production.
Chaste berry modulates the hormone prolactin with the neurotransmitter dopamine. The active ingredients such as polyphenols in the herb indirectly affects hormones and neurotransmitters and regulate the hormones.
Chaste berry herb is a safe and natural treatment for many women related problems.
Can Royal Jelly boost Metabolism?
September 21, 2011 12:08 PM
The metabolism is becoming more and more well known in any community all across America as something to look at when we are talking about health and wellness as this is the source of all calorie burning and at the end of the day will help you lose weight. This is, in so many ways the bottom line, losing weight will make you and keep you healthy. In these times of a fast paced life where anyone and everyone is so busy to even worry about how much calories they eat versus how much they need, a need for alternative solutions aside from just working out and making sure that more calories are burnt than eaten is needed and the scientific community acknowledges that need as proven by the tons of research done regarding weight loss and embraced by the manufacturers as they are more than willing to provide us with what we need. So through all these studies, the logic of looking at the metabolism and how to boost it all seems natural and this is why.
The word metabolism is taken from the greek language and basically means change or transformation. In simple terms metabolism is defined as the amount of energy or calories your body burns at a given period of time. Whatever we are doing, no matter if we are active or at rest we are burning energy and if compared to a car, it’s like burning fuel and the car can be turned off but us on the other hand could not. Even when sleeping we are still essentially burning up fuel, just the very fact our brain still works and we are breathing while we are asleep is already a sign that we are burning energy.
Now where it will interest us in terms of energy and overall strength is that metabolism is based on a person’s body composition and fat tends to need less energy to maintain itself as it is not an active tissue compared to having lean muscle because it continually needs more and more calories to maintain itself therefore more muscle means faster metabolic rate. Now this is where we go back to the fact that we need help when it comes boosting metabolism aside from just increasing muscle, because that is so much harder than supplementing with something all natural like Royal Jelly.
Royal Jelly and Energy Boost
Royal jelly is an animal product and derived solely from honey bees secretions. Its main function in terms of affecting the metabolism comes from its unique combination of compounds that will aid the enhancement of energy production in the cells. This combination is composed of amino acids, trace minerals, monosaccharides and enzymes that have Bioactive properties. Among the vitamins that it will provide naturally is the vitamin b-complex. This family of vitamins is well known for its muscle tissue building and energy boosting attributes. Another way that researches feel is a way it increases energy is through promoting overall well being since royal jelly has been related to increased production of several neurotransmitters in the body like serotonin and dopamine.
How Does Prickly Pear Leaf Help with Blood Sugar Control?
August 02, 2011 02:02 PM
Prickly pear leaf is obtained from a group of cacti known for their positive effect on blood sugar. It is an important source of food and medication for Native Americans since prehistory. It contains unique compounds that display potent antioxidant activity. Studies have shown that its phytochemical content displays potential in the management of blood sugar and the treatment of type 2 diabetes mellitus.
Also known as nopales in its place of origin, all plant species referred to as prickly pear belong to the genus Opuntia. This genus comprises more than 200 species, but only a few are noted for their culinary uses. In Mexico and most of Latin America, it is consumed as a vegetable in general. The juice extracted from the prickly pear leaf is utilized in different niches of many industries. In food and drug industries, it is highly valued for its alkaloids and polyphenols that exhibit Bioactive properties.
Many health problems recorded in the past few decades have been linked to uncontrolled blood sugar levels. Complex carbohydrates present in the human diet are broken down into simple sugars. In particular, glucose refers to the sugar that enters the systemic circulation. Glucose takes on a central role at the cellular level. It fuels the physiological functions of all cells and tissues, including the brain and the heart. That being said, diets high in simple sugars have been tied to elevated blood sugar.
Researchers and medical professionals have noted several factors that lead to metabolic disorders. Genetic abnormalities are something we don’t have control of. On the other hand, lifestyle factors are quite the opposite. It has been reported that sedentary lifestyle and food choices play a major part in the development of illnesses related to glucose metabolism. Experts are convinced that some foods are detrimental to health, but there are sources of nutrition that help maintain healthy glucose levels.
Prickly pear leaf belongs to the group of foods that are good for blood sugar. Glycemic index measures how carbohydrates present in our diet influence blood sugar concentration. Simple sugars are always considered unhealthy forms of carbohydrates in that all of them possess a high glycemic index, which means glucose is released into the bloodstream at a very rapid rate. Foods that are easily digested to simple sugars, such as white bread and sweetened beverages, affect blood sugar in the same manner. Organic compounds that occur naturally in prickly pear leaf have a twofold effect. First, it helps lower the glycemic index of carbohydrates in our diet, and thus promotes a gradual release of glucose into the bloodstream. Second, it improves the hormone activity of insulin and fights its functional decline that results in insulin resistance, a common medical condition that precedes type 2 diabetes mellitus.
Grab some prickly pear leaf and take control of your life.
Triphala - Boost digestion, Improve Liver Function, Blood Sugar, Cholesterol And More
May 27, 2011 11:42 AM
What is the Ayurvedic Herb Triphala and What Does it Do for the Body?
Triphala, or “three fruits”, is an herbal preparation that originated from India. As its name suggests, it is made up of fruits extracts from three different plant species, namely: amla, beliric, and haritaki. These plants are native to India, but enjoy a significant presence throughout the tropical and subtropical regions of Asia. Their historical uses are largely medicinal, with the exception of amla.
Allays Digestive Problems
The organic compounds that occur naturally in triphala have several properties that aid digestion and prevent gas. Triphala is often taken before meals as an appetizer because it increases digestive activities necessary for the perception of hunger. It is also widely used as a treatment for constipation for two reasons: it works as a mild laxative that induces the fast passage of foods and stimulates peristaltic movements in the colon.
Improves Liver Function
Triphala is especially good for the liver. For one, its addition to the diet speeds up the breakdown of Bioactive compounds in the gastrointestinal tract. Regular intake of triphala has been observed to improve several liver functions, most notably the conversion of cholesterol to bile salts, which is crucial for the processing of lipids in the diet. More importantly, it raises the capacity of the liver to deal with harmful metabolites of foreign materials, such as drugs.
Regulates Blood Sugar
Practitioners of Ayurvedic medicine recommend larger consumptions of triphala to individuals suffering from glucose intolerance, diabetes mellitus, and metabolic syndrome. The fruits that constitute triphala are known for their ability to interfere with the releases of simple sugars, such as glucose, into the systemic circulation. They work on the principle of sustaining a gradual but steady distribution of glucose to individual cells for several hours.
Lowers Bad Cholesterol
It is common belief in parts of Asia that triphala is good for the circulatory system. Apart from its putative role in the regulation of blood sugar, it also impacts overall lipid levels in the blood. The phytochemical content of triphala enables it to have an effect on the productions of very-low-density lipoproteins, precursors of low-density lipoproteins, or bad cholesterol. This results in fewer free fatty acids that often get trapped in arterial walls.
Promotes Healthy Metabolism
Athletes are likely to benefit from triphala, for it influences the conversion of Bioactive compounds to energy for use by cells. Triphala appears to increase metabolic rate and facilitate better utilization of glucose and fats, the reason why it is now commercially touted as an herbal supplement that aids weight loss. Also, triphala has been observed to regulate water retention, which has been linked to obesity.
Protects Eye Tissue
Triphala contains a host of antioxidants that protect eye tissues. The eyes are susceptible to oxidative stress brought on by free radicals and other reactive oxygen species. Oxidative stress interrupts functions of ocular cells and damages cellular organelles, leading to many known diseases of the eye. Triphala has been associated with the prevention and amelioration of conjunctivitis, cataracts, glaucoma, and myopia.
Triphala being a fiber has a wide range of health benefits, give triphala a try today and feel the difference!
What is the Transfer Factor in Colostrum?
May 26, 2011 12:12 PM
Colostrum, Transfer Factor, And Your Health.
Transfer factor refers to any immune molecule found in the milk produced by the mammary glands in the first days after childbirth. It comprises a group of amino acids that are smaller than cells. Since its discovery in the 20th century, it has been suggested as a treatment for a host of diseases, including cancer, diabetes, infertility, fibromyalgia, Alzheimer’s disease, asthma, hepatitis, herpes, and HIV. It has grown in popularity in the past few years due to a resurgence of interest in natural remedies.
The quality of milk that mammals make in the last weeks of pregnancy is called colostrum, which is believed to be superior to ordinary milk. For one, it is lower in lipids and fats, but higher in proteins. More importantly, it contains antibodies called immunoglobulins, which are central to the identification of bacteria and viruses during infections. These antibodies alert the rest of the immune system to effectively deal with pathogens encountered for the first time. Colostrum contains transfer factors.
Like any other form of milk, colostrum is subjected to the digestion process when taken orally. The human gastrointestinal tract treats the carbohydrates, proteins, and even antibodies present in colostrums just like any other Bioactive compounds, which are either absorbed or excreted. With the sole exception of transfer factors, everything else undergoes first pass metabolism in the liver. Transfer factors are so small that they pass through physiological screens and filters.
It is becoming common knowledge that transfer factors have antibiotic properties. Indeed they are one of the antibiotics that occur naturally in nature. They are produced by the mammary glands for the sole purpose of transferring the immunity of the mother to the newborn child. Newborns are completely sterile, making them especially susceptible several hours after birth. Transfer factors prepare the immune system of newborns against common pathogens the mother has encountered before.
One of the unique characteristics attributed to transfer factors in colostrum is its antiviral properties. Transfer factors were first observed to interfere with the rapid multiplication of rotavirus, which causes diarrhea in infants. More recent studies have looked into its medicinal potential against other viruses, such as human immunodeficiency virus and herpes. The scientific community has not come to a conclusion yet, with most of the antiviral researches on transfer factors being in their initial stages.
Transfer factors have been linked to faster muscle recover. Proponents believe that the group of proteins that constitutes transfer factors is capable of speeding up the healing rate of skeletal muscles after intense physical exertion. They raise the stress tolerance of individual cells amid harmful levels of aerobic metabolism. By so doing, they also make a viable treatment for muscle weakness and physical fatigue following continued exposure to stress without taking adequate time for recovery.
Boost Your Immune System with Colostrum Daily, you are never to young!
Vitamin B2 Is Good for Nutrient Metabolism, Cellular Energy, And More
May 10, 2011 11:11 AM
Vitamin B2 is an essential nutrient. As its name suggests, it belongs to the B complex group of vitamins. The monosaccharide ribose is part of its chemical composition together with the ring moiety called flavin that gives its yellow coloration. Hence, it is also known by the name riboflavin. Inside the human body, it plays a central role in the synthesis of flavoproteins, which are involved in many chemical reactions, especially in the metabolism of other micronutrients and Bioactive molecules.
Deficiency in riboflavin is quite common as it is routinely excreted through the urine. Common symptoms include sore throat, seborrheic dermatitis, lower blood count, all of which have been tied to higher incidence of esophageal cancer. Chronic ariboflavinosis, the medical condition caused by vitamin B2 deficiency, has been reported to contribute to carcinogenesis. The good news is that it can be easily reversed with regular intake of foods rich in riboflavin or supplementation.
Aids Nutrient Metabolism
It is not a coincidence that vitamin B2 deficiency is often accompanied by deficiencies in other vitamins and minerals. In some cases, deficiencies may be attributed to impaired liver function or intestinal absorption. That being said, low levels of riboflavin do impact the metabolism of other vitamins, such as vitamin A, vitamin B3, vitamin B6, and vitamin B9, among other water-soluble micronutrients.
Metabolites of riboflavin are required in the conversion of these vitamins to their active forms, for example, from vitamin A to retinoic acid, vitamin B6 to pyridoxic acid, vitamin B9 to folic acid. Furthermore, the metabolism of Bioactive compounds, including fats, proteins, and carbohydrates, also necessitates the presence of this vitamin, the reason why it greatly impacts growth and development in children.
Increases Cellular Energy
In addition to its physiological potential in intermediary metabolism, vitamin B2 is also present in the generation of adenosine triphosphate, the primary transport of energy that powers intracellular activities. Adenosine triphosphate is synthesized in three different metabolic pathways, and one process called oxidative phosphorylation necessitates the involvement of flavin adenine dinucleotide, one of the active forms of riboflavin.
Vitamin B2 is an important cofactor in all chemical reactions that result in an increase or decrease of oxidation state. These reactions are collectively called oxidation-reduction, or simply redox. Metabolites of riboflavin are reliable oxidizing agents capable of carrying high-energy electrons needed for oxidative phosphorylation. They also participate in beta oxidation, another metabolic pathway that yields cellular energy.
Scavenges Free Radicals
A nucleic acid derivative of riboflavin is an important constituent of a special class of organic compounds called flavoproteins. These proteins are found in almost all cells of the human body, and one of their functions is to protect the cells from oxidative stress brought on by free radicals. Vitamin B2 is present in the production of cellular energy and the removal of harmful by-products of energy metabolism.
Insufficient intake of vitamin B2 is deleterious to human health, inasmuch as its biological roles are quite pervasive at the molecular level. Do you get enough Vitamin B-2?
How Does Glutathione Work in the Body to Detox
May 06, 2011 10:11 AM
Glutathione a Body Detox
Glutathione belongs to the category of antioxidants that the human body can synthesize. It is an organic compound that is quite pervasive in nature as it is found in many multicellular organisms, microscopic or not. Almost all plants and animals are capable of producing glutathione, and, like human beings, they utilize this substance to neutralize free radicals and detoxify heavy metals.
Scavenges Free Radicals
It is common knowledge that free radicals are harmful to our body. It damages tissues, proteins, and even DNA. Free radicals are highly reactive by-products of cellular respiration. Cells utilize oxygen to power their activities, but in the process produce a group of compounds called reactive oxygen species, which change into radicals, harming cell organelles when not disposed of and raising cellular toxicity.
Glutathione is in the employ of every cell, for it is a fundamental part of the antioxidant defense of cells. Throughout the body, it is usually found in its reduced form, which donates reducing equivalents to reactive oxygen species. Glutathione becomes reactive in the process, but easily reacts with other reactive glutathione to form glutathione disulfide. Antioxidant enzymes manufacture glutathione in the presence of glutathione disulfide. This process constitutes the antioxidant mechanism of all cells.
Detoxifies Liver Metabolites
Metabolism is a complex process. Bioactive compounds in the foods we eat produce metabolites and by-products that are not necessarily good for our health. In fact, most of the drugs and medications we take directly harm us. Fortunately, the liver comes to our defense. For example, alcohol is converted into large amounts of acetaldehyde in its first stage of metabolism, creating effects we usually refer to as hangover.
The presence of glutathione enables the liver to easily recuperate from the damages brought on by harmful metabolites. That being said, glutathione in its reduced form does get depleted. One good example is drug overdose. The analgesic paracetamol, or acetaminophen, is known for its toxic by-product that induces liver failure in the absence of glutathione. Drugs are immediately detoxified in the liver with the help of glutathione. Low levels of glutathione may even result in death as is the case with paracetamol overdose.
Expels Foreign Materials
A number of substances in our diet are considered xenobiotics, or foreign materials, by our body. Most of them passes the alimentary canal undigested and enters the colon together with waste materials. However, there are substances that readily undergo absorption in the small intestines, such as trace elements and heavy metals. They pose considerable threats to health when they enter the systemic circulation in large quantities.
Glutathione is one of the compounds that keep xenobiotics in check. It facilitates the excretion of heavy metals and many known toxins. Glutathione conjugation plays a major role in detoxification and quite common at the cellular level. It makes sure that foreign compounds do not undergo reabsorption once it reaches the kidneys, effectively washing them away through the urine.
How Does Zinc Boost the Immune System and What Else Does this Mineral Do
May 02, 2011 01:58 PM
Zinc And Good Health!
Zinc is considered a transition metal in general, and as such one of the most abundant transition metals in living organisms, including human beings. It plays a central role in the molecular structure of proteins, which is indispensable in catalytic activities of over a hundred enzymes. These proteins belong to all enzyme classes and have far-reaching effects on the human body, notably in the immune system.
In the past few decades, the scientific community has unearthed countless chemical reactions that take place inside the human body. A number of these reactions necessitate the presence of zinc. While zinc is considered toxic in high amounts, it is classified as an essential trace mineral, which means it has a daily value. A deficiency in zinc has serious effects on growth and development as implicated in the life cycle of cells.
Stabilizes Cellular Structures
Zinc is a trace mineral that is quite pervasive at the cellular level as all cells have zinc demands. This dietary element keeps cells in prime condition and maintains the health of cell organelles. For one, zinc is required to stabilize ions that functions as interaction modules responsible for binding DNA, RNA, and other particles found within cells. The absence of zinc in cells will cripple these activities.
The complete absence of this trace mineral is improbable, but low levels of elemental zinc in the body have been observed to have serious effects on cellular health. The capacity of cells to contain radical damage depends on the availability of zinc. Depleting levels of zinc result in an impaired antioxidant defense and greater susceptibility to free radicals and other reactive oxygen species.
Induces Enzymatic Reactions
Enzymes are proteins that play functional roles in the metabolism of Bioactive compounds. They are categorized into many classes, depending on their catalytic functions. These functions are vital as they are one of the mechanisms in the employ of the body to sustain homeostasis. Some classes are involved in immune responses in the prevention of disease and the alleviation of chronic disorders.
All classes of enzymes are affected by the metabolism of zinc one way or another, with over a hundred requiring the direct involvement of zinc to induce catalysis. Zinc is of special note in a chemical reaction called hydroxylation, a process that helps cleanse the body of toxins. With hydroxylation, zinc participates in the conversion of lipid-soluble substrates into water-soluble products ready for excretion.
Modulates Immune Responses
The human body utilizes zinc in many different metabolic pathways that influence the processes needed for prompt immune responses. In the case of common infections such as colds and flu, zinc curtails severity of symptoms and raises immune responses to optimum levels. More importantly, healthy levels of zinc enable the body to take on preventative measures against diseases.
Remember even though zinc is an important mineral, to much can cause problems as well. Do not exceed 150mgs daily for extended periods of time to maintain safe levels of zinc. I suggest 15mg to 75mg daily.
Why is Maca Called the Peruvian Ginseng and What Does this Herb Do
April 28, 2011 03:17 PM
Maca: Stress, Energy, Libido, and More.
Maca is a root vegetable traditionally grown at high altitudes in Peru. It is related to radish and turnip, both of which it resembles in appearance, size, and proportion. Its historical uses denote its adaptogenic properties, the reason why it is often called the Peruvian ginseng today. It is the subject of numerous studies underway, and preliminary results point to its effects on the endocrine system.
Lepidium meyenii is a plant species that belongs to the Brassicaceae family, which comprises over three thousand species of edible plants called cruciferous vegetables. Hence, maca is related to many green leafy vegetables such as cabbage, broccoli and cauliflower, among others. Like these vegetables, maca contains an assortment of organic compounds that display Bioactive properties.
Lepidium peruvianum refers to the same species. Modern herbalists argue that it is a more accurate scientific name for maca, though Lepidium meyenii remains in use in the scientific community. Until only recently, maca was exclusively cultivated in the Andes of Peru. Due to an increased interest in alternative forms of medicine in North America and Europe, it has enjoyed a sudden surge in popularity in the past few years.
Enhances Stress Resistance
Maca is marketed as an adaptogen, a natural remedy for stress. It has been compared to ginseng a number of times, earning itself the moniker Peruvian ginseng. Maca and ginseng do not interact with hormones in the body but rather contain phytochemicals that directly act on endocrine glands, including the hypothalamus, adrenals, and thyroid glands. These organs are pivotal to better management of stress. Several herbalists argue that maca is even more potent than ginseng in that it is believed to affect almost all endocrine glands and create a homeostatic effect on the chemical compounds that they secrete.
Modulates Energy Metabolism
The nutritional profile of maca has been described to be a combination of the nutrients found in whole grains and green leafy vegetables. It contains significant amounts of amino acids and dietary fiber. Its carbohydrate content accounts for 60 per cent of its dry weight, with emphasis on its low glycemic index. Its active constituents enable its carbohydrates to break down at a slow pace and release glucose into the bloodstream without raising blood sugar levels. By so doing, it provides the energy needed to fuel physical activities and athletic performance for extended periods of time.
Improves Sexual Performance
Maca is a popular aphrodisiac. In the old days, Inca warriors consumed large quantities of maca roots for the sole purpose of achieving desired virility. In addition to its energy-boosting and stress-relieving effects, regular intake of maca impacts sexual health as it contains organic compounds that stimulate gonadal tissues, especially in men. Randomized clinical trials have observed that maca affects semen quality, increases sperm count, and improves sexual performance, making it an ideal choice of supplement for men.
Maca root is an excellent herb for men and women. You can gain energy as well as a boost in energy with Maca root. Try maca root and feel the difference it can make on your life!
What is Bioperine and How Does It Help with Absorption of Vitamins
April 21, 2011 03:14 PM
Get more from your food with Bioperine.
Bioperine is a patented form of an alkaloid found in black pepper. It is derived entirely from piperine, an organic compound responsible for the spicy taste of black pepper and long pepper. Piperine has been noted for its thermogenic properties believed to speed up the absorption metabolism of digested foods. Recent studies have discovered that it also interferes with the release of enzymes that govern the bioavailability of drugs and supplements. By so doing, it enhances the rate of absorption of vitamins.
The human body has a complex mechanism of controlling the substances that get in and out of systemic circulation. The first pass occurs in the alimentary canal, where gastrointestinal enzymes break down substances into smaller compounds. It is believed that a very small percentage manages to undergo intestinal absorption after digestion. In general, this is the part where constituents of supplements remain undigested and instead enter the colon together with waste materials.
The liver plays a central role to the metabolism of drugs and most Bioactive compounds. The compounds that pass the intestinal walls and enter the hepatic portal system, a group of veins that direct blood and other compounds from the gastrointestinal tract to the liver, is further metabolized inside the liver. Anything that the body considers foreign is sent to the kidneys and easily excreted through the urine. This is the reason why bioavailability is significantly reduced after ingestion.
Counteracts Effects of Enzymes
Bioperine is the only compound known to interact with enzymes that controls the metabolism of foreign materials within the intestinal epithelium. P-glycoprotein is released in the digestive tract to deal with drugs and xenobiotics found in our diet. Vitamins are no exception to the tightly regulated process of absorption in the intestines. These enzymes transport digested compounds to the liver.
It has been observed that piperine appears to reduce the expression of p-glycoprotein in the alimentary canal and other parts of the body. Proponents believe that bioperine, a purer form of piperine, is capable of counteracting the effects of the enzyme within the intestinal epithelium, making it easier for vitamins and supplements to enter the hepatic portal system.
Increases the Rate of Metabolism
Not all compounds that undergo the first-pass effect interact with the cells and tissues they are supposed to act on. If they should have an effect on any cell, they are still subjected to the actions of enzymes specialized for the expulsion of xenobiotics found in the systemic circulation and the rest of the body. For example, CYP3A4 removes foreign materials from the cells and facilitates their excretion.
Bioperine is touted to induce thermogenesis and stimulate cellular activities. By so doing, the effects of Bioactive compounds are achieved while they remain inside the cells and tissues. The thermogenic properties of bioperine influence the rate of metabolism of digested compounds, including vitamins, minerals, and components of herbal preparations. Note that it can increase the update or prescription medications as well, so caution should be observed when consuming bioperine with medications.
If you want to give your body a nutrient boost, add bioperine to your supplement regiment to boost absorption.
Can Royal Jelly Really Boost Energy?
April 18, 2011 02:25 PM
Royal Jelly as an Energy Boost
Royal jelly is an all-natural animal product entirely derived from the secretions of honey bees. It is commercially touted as an energy booster because of its unique combination of compounds that help produce energy in cells and promote mental clarity. It contains an abundance of monosaccharides, amino acids, fatty acids, trace minerals, and enzymes, all of which have Bioactive properties.
Inside a honeycomb, royal jelly is obtained from queen cells. These secretions are actually fed to all larvae, but only queen larvae are fed with royal jelly in amounts that can be harvested. This is the reason why royal jelly is considered rare. That being said, recent innovations in the manufacture of honey and the overall beekeeping process have contributed to increasing productions of royal jelly.
Contains Vitamins and Minerals
Royal jelly is available as a dietary supplement noted for its high vitamin and mineral content. It is a natural source of vitamin B complex, notably pantothenic acid (vitamin B5) and pyridoxine (vitamin B6). It has relatively high amounts of simple sugars and fatty acids, both groups are biological precursors of cellular energy. In general, it contains up to 15 per cent carbohydrates and 5 per cent healthy fats.
In addition to vitamins, it is also rich in enzymes that are believed to aid the fast absorption of its Bioactive compounds in the small intestine. In addition, it contains trace amounts of dietary minerals. Royal jelly is often marketed as a fast-acting energy booster because its components are believed to work synergistically in the prompt release of energy within cells right after absorption.
Improves Energy Metabolism
Coenzyme A is an organic compound produced in the human body to aid the metabolism of cellular energy. Its synthesis, however, requires the presence of pantothenic acid, a vitamin obtained largely from the diet. It is postulated that royal jelly helps increase the production of energy in that it contains pantothenic acid in amounts sufficient to affect the biosynthesis of coenzyme A.
Royal jelly is also noted for its pyridoxine content. Pyridoxal phosphate, or pyridoxine, is the active form of vitamin B5. It is necessary for the metabolism of protein, glucose, and lipids. It is of special significance in yielding energy from glycogen, which it converts to glucose. The combination of fatty acids, simple sugars, and B vitamin in royal jelly enables it to bring about a noticeable energy boost.
Creates Feelings of Well-being
Royal jelly has been linked to an increase in the release of major neurotransmitters, especially serotonin, dopamine, and glutamate. Serotonin is dubbed the happiness hormone. Dopamine is linked to rewards-seeking behavior and keeps interest in repetitive tasks. And glutamate is a major excitatory neurotransmitter in the central nervous system. Together they sustain mental focus.
The roles of its components and their metabolites in the production of energy and release of brain chemicals are the reason why royal jelly creates feelings of physical and mental well-being.
Royal Jelly Use It
As you can see, royal jelly is rich in many nutrients to support a health brain and metabolism. If you are seeking more energy, give royal jelly a try!
What Makes Organic Raw Almonds so Good for My Health?
April 16, 2011 10:10 AM
Eat Organic Raw Almonds for Good Health.
Almonds are widely cultivated for its nuts, which are rich in vitamins and minerals. Throughout history, almond nuts have enjoyed a significant presence in many cuisines from all over the world. In fact, they are one of the best known nuts, rivaled only by peanuts in popularity. In recent years, almond nuts have been tied to alkaline diet, which consists of healthy foods touted to be alkaline-forming.
Prunus dulcis, the scientific name of almonds, is believed to have been domesticated earlier than the ancient times, with earliest evidence dating back to more than 2000 years ago in what is now known as the Early Bronze Age. This species is one of the ancient fruit-bearing trees grown commercially that remains popular to this day largely owing to its capacity to easily grow and bear fruits without the aid of grafting.
Organic almonds are different from other almonds grown the conventional way in that, as the name suggests, they meet the standards for organic farming, a method of food production that does away with chemicals known for their potential threat to the human health. In addition to being the only nuts considered alkaline forming, it contains higher levels of Bioactive compounds noted for their nutritional significance.
Decreases Acidic By-Products
Almond, the only alkalizing nut, works on the principle of rebalancing the body’s pH. Proponents of alkaline diet believe that foods that are identified to be alkaline-forming aid the body in maintaining homeostasis and restore pH imbalances in the human body. It follows that foods that are acid-forming gradually contribute to the formation of diseases. Organic almonds, guaranteed to contain none of the chemical compounds known to produce acidic by-products, help rebalance the overall pH of the body.
Enhances Mental Performance
Nuts have always been touted as foods for the brain. Organic almonds are different from other nuts because it is not even a nut in the first place. It is a drupe that contains a large seed, which is sold and consumed exactly like other nuts. These seeds contain an abundance of nutrients, such as magnesium, phosphorus, iron, B vitamins, and many others, all of which work hand in hand in increasing neuronal activities in the brain and the central nervous system, thereby enhancing mental performance.
Prevents Many Known Diseases
One cup of organic almonds is enough to meet the recommended daily intake for vitamin E and magnesium, two nutrients that have been the subject of extensive study in the past few years for their purported role in medicine. Vitamin E is an antioxidant that is pervasive at the cellular level. Magnesium improves health by raising the production of energy needed for cellular functions.
Organic almonds have been linked to the treatment of many different diseases, such as diabetes, cardiovascular diseases, cancer, and digestive problems. More importantly, they are one of the sources of food consistently recommended by experts on the alkaline diet.
Most importantly, raw almonds are full of nutrients and phytonutrients. Have you had your raw almonds today?
Is There Any Benefit to Taking Grape Seed Extract?
April 15, 2011 02:12 PM
Grape Seed Extract And Your Health!Grape seed extract has been linked to many health benefits. It is entirely derived from grape products, but contains higher concentrations of organic compounds naturally occurring in grape seeds. It has long been known that grapes are excellent sources of Bioactive compounds while grape seeds have more phytochemicals. In addition to their long list of all-natural antioxidants, such as tocopherols, flavonoids, and oligomeric proanthocyanidins, grape seed extracts contain the essential fatty acid linoleic acid, the reason why they are exceptionally good for the skin.
Accelerates Wound Healing
The circulatory system is the best venue for nutrient distribution throughout the body. The tissues that have direct access to the blood vessels are more likely to receive nourishment and heal faster in the process. Grape seed extracts induce the productions of proteins called vascular endothelial growth factor, which stimulates the growth of healthy blood vessels, thereby accelerating wound healing in any part of the body.
Improves Bone Density
Grape seed extracts have been noted to increase bone mass and strength. The bones are the primary storage of inorganic minerals in the human body, like elemental calcium. As such, they undergo a lifetime cycle of resorption and reabsorption to respond to the mineral needs of other body parts. Any imbalance in the process may result in bone porosity. It is postulated that the phytochemical content of grape seed extracts inhibits bone resorption.
Promotes Integumentary Health
Oligomeric proanthocyanidins, or OPCs, are of special note for their unique antioxidant activities. They are capable of scavenging free radicals and preventing cellular damage. At the same time, they protect the skin, the scalp, and the rest of the integumentary system from the harmful oxidative effects of ultraviolet rays. Grape seed extracts are particularly rich in OPCs, which have been tied to impede skin tumor growth.
Shows Cardioprotective Effects
Grape seed extracts contain an abundance of organic compounds that promote cardiovascular health. First, it has shown to be effective in lowering low-density lipoproteins, also known as bad cholesterol. Second, its antioxidant properties prevent the oxidation of bad cholesterol, which results in the formation of arterial plaques if subjected to oxidative stress. Third, grape seed extracts reduce complications of preexisting cardiovascular disorders.
Eases Digestive Problems
Grapes have long been reputed as a digestive in many cultures. Grape seed extracts, having flavonoids with Bioactive properties, serve as a cleanser of the alimentary canal. They aid digestion and modulate the effects of enzymes on food. The same organic compounds limit the growth of microorganisms that populate the colon, which is the cause of many disorders of the gastrointestinal tract.
Prevents Tooth Decay
Grape seed extracts contain phenolics that interfere with the metabolism of sugars in the oral cavity. The bacteria that take up residence in the mouth rely on the availability of saccharine compounds, and they thrive well in the presence of simple sugars, such as sucrose, fructose, and glucose. Dental carries result from an abundance of these sugars and a growing bacterial population. Grape seed extracts impact both.
As you can see, grape seed extract has many health benefits. All who want to keep their body’s working in tip top shape should be taking grape seed extract daily!
What is Vinpocetine and How Does it Help with Memory?
March 24, 2011 02:18 PM
Vinpocetine And Brain Health
Vinpocetine is a derivative of an organic compound found in the plant species Vinca minor, or common periwinkle. It is best known for its neuroprotective effects and used in Europe and Japan in treatment of age-related cognitive decline. More often than not, its activities inside the human body are described as vasodilator, which means it increases blood flow. It has also seen a growing presence in the North American market as a dietary supplement.
Vinpocetine is available as a prescription drug in certain European countries and Japan and has shown to be speed up prognosis of patients who suffered cerebrovascular accident, or CVA, which is commonly referred to as stroke. Most cases of cerebrovascular accident are brought on by ischemia, or very poor circulation of blood to certain parts of the brain. This is exactly what vinpocetine is beneficial for, and recommended dosages have so far yielded very encouraging results.
Improves Blood Circulation in the Brain
It has long been postulated that one of the mechanisms of action of vinpocetine is limiting the effects of Na+ channels that are sensitive to voltage. This creates a neuroprotective effect believed to contribute to mental clarity and sustained attention. Striatal nerve endings produce extracellular Ca+ ions that induce neuronal damage through a phenomenon called excitotocity. High levels of Ca+ ions are now alleged to be correlated with voltage-sensitive Na+ channels. Striatal nerve endings see a decline in Ca+ ions when Na+ channels are influenced by vinpocetine, and in the process lessen excitotoxicity.
Attenuates Ischemic Neuronal Damage
In addition to limiting neuronal damage induced by excitotoxicity, which in turn results from cerebral ischemia, vinpocetine plays an active role in the upkeep of brain cells after being subjected to ischemic damage. As a vasodilator, it not only counters the effects of ischemia but also significantly increases the brain’s access to Bioactive molecules like oxygen and other nutrients exclusively distributed by the circulatory system.
It also inhibits the enzyme phosphodiesterase, which is specialized for the breakdown of cyclic adenosine monophosphate, or cAMP, and cyclic guanosine monophosphate, or cGMP. By so doing, vinpocetine contributes to glucose metabolism and energy production in the brain, and at the same time, improves the distribution of Bioactive compounds in the central nervous system.
Displays Neuroprotective Activities
Vinpocetine and its precursor belong to a group of indole alkaloids known as tryptomines, which are present in the human brain and the rest of the central nervous system in minute quantities. These organic compounds make up several psychoactive drugs and in the human body act as neuromodulators and neurotransmitters in the form of melatonin and serotonin.
Vinpocetine in particular displays activities that are primarily anti-inflammatory in nature. Several studies point to its effects on the enzyme complex called IkB kinase, which regulates cellular responses to inflammation, by preventing the translocation of a protein complex called responsible for the process of inflammation within cells.
In a Nutshell, vinpocetine can help you think clearer and protect the brain from inflammation and free radical damage. Give vinpocetine a try today!
What is Dandelion Tea Good for?
March 08, 2011 02:38 PM
Dandelion tea must be best known as a detoxifying beverage that has been associated with improving liver and kidney functions. In the old days the plant is often considered a pesky weed, but today health organizations, such as the European Scientific Cooperative on Phytotherapy, have endorsed its efficacy in relieving liver problems among others. The tea produces a pronounced bitter taste and is often sweetened, but it also packs large quantities of micronutrients.
Peoples from the Old World are no stranger to dandelion tea, but the plant species are native to both Europe and North America. What we refer to as dandelion comprises a large group of flowering plants. The two most notable species are Taraxacum officinale and Taraxacum erythrospermum, both of which are used to make dandelion tea. The fact that it can be found right in your yard is the reason why health magazines regard this herb as one of the readily available nutritional powerhouses.
Maintains Intake of Nutrients during Weight Loss
Dandelion tea has been noted to contain significant levels of vitamins and minerals, the reason why it is popular among individuals who are following a weight-loss program. Many people seem to overlook the fact that depriving themselves of important food sources, such as whole grains, compromises their daily intake of dietary nutrients. Chronic dieting is particularly dangerous in the long run even for those who used to be physically healthy. Dandelion tea offers a solution to people on a diet by meeting the RDA for vitamin A and K and providing up to 30 per cent of vitamin C and vitamin B7. It is also rich in minerals like calcium, potassium, and iron.
Promotes Excretion of Toxins through Diuresis
Not surprisingly, dandelions have been used to aid a long list of symptoms and diseases, and it has been reputed as a natural diuretic for centuries. Due to its worldwide distribution, it is one of the few herbs that have earned visible presence in traditional medicine of the East and the West, and its use has always had something to do with the proper functioning of the liver and the kidneys. The bioflavonoids found in dandelion remove toxins from the liver, like ethanol metabolites, and facilitate their excretion through the urine.
Facilitates Absorption of Bioactive Compounds
Health professionals often point to the nutritional content of dandelion tea and other products from the herb. Most species of dandelions have been documented to be completely edible, and the quantities of Bioactive compounds present in them have been compared with vegetables like spinach and broccoli. Consumptions of dandelions have even been considered tantamount to intake of dietary supplements as they are rich in phytochemicals that display the activities of many known polyphenolic substances found in black and green teas and other foods rich in antioxidants. While the plant contains high quantities of protein, carbohydrates, and fiber, the tea has been tied to more effective absorption of these Bioactive compounds, making it an ideal beverage to match with any food source.
How does Acetyl-L-Carnitine Help With Heart Health?
February 21, 2011 02:37 PM
Acetyl L Carnitine And Heart Health
Acetyl-L-Carnitine is a form of the chemical compound carnitine, which is active in the human body as the amino acid L-carnitine. It is an organic substance that is naturally occurring in mammals and many other animals, and it is released from the liver and kidneys to every tissue in the body. While our body is capable of manufacturing this amino acid, there are factors involved in its depleting levels at certain times, and thus it is made available as a nutritional supplement. Today it is primarily used as a treatment for heart diseases and other cardiovascular problems.
Helps Break Down Fats
One of the many factors that influence heart tissues is high levels of free fatty acids in the blood. Popular health magazines and the mainstream press have labeled transports of fat-soluble Bioactive compounds in the water-based bloodstream as bad cholesterol, but free fatty acids are also to blame for the buildup of fatty debris in the blood vessel linings, resulting in the thickening of walls characteristic of many cases of heart diseases.
The body has a mechanism to utilize these fats more effectively in the presence of Acetyl-L-Carnitine, which is quite active as soon as it enters the cells of any tissue, notably muscle and skeletal tissues. Free fatty acids are formed as a by-product of triglycerides that remained in the blood, but once they pass the cell membranes, they can be a source of energy far more powerful than that produced from glucose. Acetyl-L-Carnitine makes it possible for these fatty molecules to be converted into energy.
Maintains Heart Wellness
Every cell has its own form of storage fuel, and glucose and its metabolites are probably the best known. However, tissues of the heart and the muscles prefer fatty acids. As you might have surmised, tissues found in the heart and those that build the form of our physique, classified as cardiac and skeletal respectively, needs more energy than other tissues of our body. The skeletal muscles are directly involved in daily physical exertion whereas the heart is, of course, in constant movement.
Fatty acids yield adenosine triphosphate, or ATP, the form of energy at the cellular level, which is in general more than two times the energy produced from either carbohydrates or proteins. This is one of the reasons why fatty acids can keep up with the hard work associated with cardiac and skeletal muscle tissues. The absence of energy required for the healthy functioning of the heart leads to cell death and affects the heart’s ability to pump blood as described in cases of heart failure.
Promotes High Bioavailability
Acetyl-L-Carnitine has been touted to be more absorbable and ultimately incorporated in body tissues more effectively than other forms of carnitine. It is a known fact that acetylating organic molecules increases the effectiveness of administered doses, and this remains true with Acetyl-L-Carnitine, the reason why it is widely applied in serious medical conditions concerning the heart.
If you have heart problems, give Acetyl-L-Carnitine a try risk free.
Can N-Acetyl Cysteine Boost Liver Health And Function?
February 10, 2011 12:31 PM
N-Acetyl Cysteine (NAC) And The Liver
N-Acetyl Cysteine or NAC is an antidote for poisonous effects of paracetamol overdose. It targets the cells in the liver, raising their capacity to deal with harmful metabolites. There are a number of researches well underway that scrutinizes a variety of medical conditions for which this compound could be of use. It is a known precursor of antioxidants and in itself a scavenger of peroxides and free radicals.
Hepatocytes are the cells that take on most of the functions of the liver and account for more than 70 per cent of the liver’s total mass. These cells are responsible for the presystematic metabolism of drugs, also known as the first-pass effect, rendering most drugs innocuous before they are released into the bloodstream. The total amounts of Bioactive substances that are distributed to the rest of the body are also largely regulated by hepatocytes, notably carbohydrates. In addition, they are involved in the biosynthesis of protein, cholesterol, phospholipids, and bile salts as well as the functional reserves for protein.
Hepatocytes and Toxins
Certain drugs produce toxins when broken down by hepatocytes. A classic example is the metabolism of ethanol into acetaldehyde, which is a toxic compound, a probable carcinogen, and an air pollutant emitted by combustion of cars and tobacco smoking. While hepatocytes are known for their detoxifying responses to toxic substances entering the body, the metabolism of toxins actually takes up a great deal of time, resulting in certain toxins getting released into the bloodstream prior to first-pass effect.
That being said, continued exposure to toxins wears down hepatocytes, and high concentrations of what we refer to as poisons is certain to bring damage to the liver. This is what happens during overdose of paracetamol, or acetaminophen. In an effort to metabolized excessive amounts of the drug, the liver cells produce by-products that are essentially poisons, which under normal circumstances can be contained well.
NAC and Glutathione Production
The major antioxidant synthesized by the human body called glutathione comes to the liver’s defense when toxic by-products are produced. Hepatocytes in particular are so dependent on glutathione in the quenching of toxins that it has been observed that any challenge to the manufacture of this endogenous antioxidant will ultimately result in liver failure.
Glutathione is released by hepatocytes in large amounts especially during the metabolism of alcohol and drugs, but during overdose the ravaging activities of ethanol or drug metabolites overwhelm the detoxifying effects of antioxidant reserves in the body. Simply put, the defense mechanisms in the employ of the body have limits. NAC resolves this problem.
The presence of NAC in the body augments the liver’s ability to produce the needed amounts of glutathione to effectively counter the harmful properties of invasive substances. In fact, the liver completely recuperates in a matter of weeks even after life-threatening conditions given that NAC is introduced in the human body in time to avoid subsequent damages to other vital organs. Indeed its application has proven to save lives in fatal cases of paracetamol poisoning.
N-Acetyl Cysteine is available at your local or internet vitamin store in capsule or tablet forms. Always choose name brands like Source Naturals to ensure quality and purity of the product you buy for better liver health.
Have you had your NAC today?
How does Malic Acid help with Fibromyalgia?
February 09, 2011 01:18 PM
Malic Acid And Fibromyalgia
If you feel sensitized to pain by otherwise harmless stimuli, then you may be experiencing symptoms of fibromyalgia, which has been recorded to affect up to 4 per cent of the population worldwide. It is characterized by a feeling of weakness in the muscles of the limbs, conscious awareness of abnormal heartbeat, problems concerning bowel movement, and disturbances to sleep patterns. All of these are complaints reported to have been addressed by supplementation of malic acid.
The medical community remains inconclusive as to what causes fibromyalgia, some claiming it’s not a disease at all. While symptoms may not be necessarily medical signs, there are innumerable cases that describe complaints we collectively refer to as fibromyalgia. Throughout the past few decades, medical professionals around the world have considered these symptoms as one musculoskeletal disease whereas most neurologists have contended that fibromyalgia is attributable to the abnormalities within the nervous system. Today the American College of Rheumatology has charted nine paired tender points in an effort to describe the symptoms for this condition better.
Known Causes in Scrutiny
The most common symptoms of fibromyalgia more often than not appear simultaneously with stress-induced medical conditions such as chronic fatigue, anxiety disorders, and depression, but they are known to develop independently. A tissue in the brain responsible for long-term memory and spatial navigation called hippocampus have shown abnormalities among patients of fibromyalgia, thereby affecting sleep patterns, perception of pain, and related cognitive functions.
In the latter half of the 20th century it is postulated that serotonin leads to fibromyalgia. Serotonin being a neurotransmitter that governs mood, attention, and pain were found to be significantly decreased in the blood plasma and cerebrospinal fluid among patients who reported to experience this condition. That being said, the introduction of serotonin inhibitors used in treatment of depression has also shown alleviations of pain-related symptoms across the tender point index.
Malic Acid and Prognosis
Malic acid was discovered as a constituent of apple juice as early as the 18th century. Reduced levels of malic acid contribute to the maturity of fruits. In human beings it plays a fundamental role as an intermediate in a metabolic pathway that influences the chemical conversion of Bioactive compounds like carbohydrates, fats, and proteins into carbon dioxide and water, which in turn convert the molecules contained in the cytoplasmic fluid of cells into energy generated in the mitochondria.
The availability of malic acid inside the human body modulates functional activities at the cellular level by speeding up the metabolism of Bioactive compounds and consequently the production of energy in use by the cells. That being said, malic acid provides vitality to muscle cells, raising their endurance against stress. In addition, there have been reports that intake of malic acid help elevate levels of serotonin, leading to improved response to pain and better management of fibromyalgia.
For now, the tender point index is the primary diagnostic tool for evaluating fibromyalgia, and the use of malic acid has been recorded to reduce pain in these points.
Have you had your Malic Acid today?
Can L-Arginine Really Help with Circulation Blood Flow?
February 05, 2011 01:43 PM
The incorporation of nutrients from our diet to the parts of the human body is taken care of by the network of blood vessels that make up the circulatory system, including the distribution of oxygen. Blood flow in effect largely contributes to the effective utilization of Bioactive substances from digested foods. The muscles that line the inner walls of blood vessels are responsible for healthy circulation with the aid of a substance that is catalyzed from L-arginine.
Arteries, capillaries, and veins are the three primary members of the vascular highway that forms the systematic circulation. The arteries from the heart branch out in smaller vascular tubes called capillaries, which are connected to the system of veins leading back to the heart. Blood continuously flows inside this complex loop of tubes and brings nutrition to the tissues at the end of capillaries.
Endothelium and Smooth Muscle Cells
Circulation is a vascular function regulated by the smooth muscle cells within the blood vessel walls that promote streamline flow to avoid turbulence. In a lifetime the flow may result in chaos, depending on the health of blood vessels. A special class of tissues exposed to the blood plasma known as endothelium stimulates the smooth muscle cells that make up most of the systematic circulation to perform its function. However, factors associated with aging interfere with the proper functioning of both the smooth muscle cells and the endothelium.
The human body possesses a gene responsible for the encoding of a group of enzymes that aid healthy blood flow in the circulatory system. This gene identified as Endothelial Nitric Oxide Synthase (NOS), as the name suggests, has something to do with the endothelium and the chemical compound nitric oxide. While chronic expression of nitric oxide in the body may lead to inflammatory diseases, this gas actually serves a focal role in preventing damage to all tissues in the human body resulting from the deprivation of blood supply.
Nitric Oxide and L-Arginine
How? Nitric oxide is produced at the right amounts by all mammals for use as a signaling agent at the cellular level. In the circulatory system, nitric oxide is known to display vasodilator properties, that is, it brings about the relaxation of smooth muscle cells that line the blood vessel walls. Vasodilation is central to circulation and blood flow inasmuch as the widening of vascular walls leads to the flow of blood. Since nitric oxide must be manufactured at healthy levels, it is regulated by Endothelial NOS.
However, its production depends on the availability of Arginine in the human body. The amino acid L-arginine is not synthesized at sufficient amounts at all times, and thus it must be derived from our diet. No one can really tell what conditions govern the biosynthesis of L-arginine, and for individuals who have poor nutrition, levels of L-arginine are significantly low. This is the reason why medical professionals advocate the use of L-arginine to counter vascular diseases. Supplementation of L-arginine has in fact been associated to healthy circulation.
Health Comes From The Honey bee
August 08, 2008 04:08 PM
The substances found in the beehive have held a treasured place in history among the ancient cultures of Egypt, Greece, Rome, China, Middle East, and the Slavic and Native American peoples. Experts have long theorized that bees came into being when flowering plants first began blossoming in abundance. The fossilized remains of pollen, leaves, and even flowers have been dated back to when dinosaurs roamed the land back when time began.
Bees collect pollen from flowers and mix it with their nectar, which transforms it into a nutrient-dense super food with Bioactive ingredients numbering in the thousands including enzymes, bioflavonoids, essential fatty acids, free amino acids, natural chelated minerals, and whole vitamin complexes. Ancient Egyptians, Orientals, Hebrews, and South American natives often applied a combination of honey mixed with bee pollen to wounds, burns, and boils, while Orientals used honey and bee pollen mixed with fruit or vegetable juice as a health drink. Norse mythology even states that honey and bee pollen were the secret to the eternal life of their gods.
Whether bee pollen is the secret to eternal life or not, there have been many studies done which show the connection between its consumption and healthy longevity. Bee pollen is seen as an immune system enhancer due to its ability to strengthen the body against viral infections. It is also effective in relieving fatigue, improving concentration, the treatment of asthma and of allergies, and in confronting skin problems and inhibiting wrinkles.
Bee pollen has also helped many women with painful menstrual cramps or hot flashes. It can also relieve headaches and heart palpitations as well as increase sexual potency, fertility, and benefit the prostate. Bee pollen can be used to regulate colon problems and as a diuretic for the kidney and bladder. Evidence has even been found for bee pollen’s effectiveness on children with ADD.
Bee pollen is packed with many different nutrients including amino acids, antibiotic factors, DNA/RNA, enzymes, glucosides, hormones, minerals, vitamins, and other ingredients that have not yet been determined. There are a total of 22 amino acids in bee pollen, including all of the essential ones, which makes it an extremely usable and complete source of protein. It is higher in protein than steak, eggs or cheese weight for weight, without large amounts of fat.
Bee pollen is rich in phytochemicals such as flavonoids, carotenes, and phytosterols, which allows it to provide important antioxidants including lycopene, selenium, quercetin, and beta carotene. Bee pollen also has the ability to regulate intestinal bacterial, which neutralizes toxic waste and improves blood health. Bee pollen contains 18 different enzymes including amylase, diastase, phosphatase, pepsin, and tryspin. Because bee pollen is such a rich source of enzymes, it greatly assists the body since they are required for all bodily functions.
Glucosides, which are natural sugars, are involved in the creation of energy within the body, can be found in bee pollen, as they promote better healing and coagulation and also control hypertension by regulating blood flow. Bee pollen contains plant hormones which activate and assist the body’s own endocrine glands, allowing them to function better, which can lead to an increased sperm count for men.
Twenty-seven different kinds of minerals can be found in bee pollen including calcium, magnesium, iron, potassium, boron, chlorine, copper, iodine, molybdenum, phosphorus, selenium, silicon, sodium, sulfur, titanium, and zinc. All known vitamins, from A through K, are found in concentrated amounts in bee pollen. With all of these nutrients present, bee pollen is an excellent addition to the diet which will ensure healthy functioning of all your body’s processes.
Detox your Body with Wasabi Rhizome
January 29, 2008 10:30 AM
The Wasabi rhizome, the underground fleshy stem of the wasabia japonica plant, is prized not only for its fiery flavour but also its effect in detoxifying the liver. However, make sure that you are getting the real McCoy since many restaurants in the USA do not use the genuine paste.
The wasabi is a plant of the cruciferous family, the same family as cabbage, broccoli, turnip, radish, horseradish and mustard, and is native to Japan and Korea and now grown on the Pacific coast of Canada. It grows best in temperate to cold climates, especially in mountainous areas where there are plenty of cold streams.
Anybody who regularly enjoys sashimi and sushi should be familiar with the wasabi rhizome, that green lump of paste lying on the side of the plate. It is hot and fiery, although not in the same way as the chilli pepper that is fiery on the tongue and in the mouth. This tends to affect the sinuses more, and leaves a sweetish taste once the initial heat has dissipated. However, it is not always what it should be.
The last comment there refers to the practise, especially in the USA, of using dyed common horseradish as wasabi paste, so be careful of that since the two are not equivalent in the health benefits they impart to your body. Although of the same family as the horseradish, and sometimes termed the Japanese horseradish, ordinary horseradish does not have the same health benefits as genuine wasabi, and does not contain the same active ingredients so do not confuse the two.
Real wasabi is normally used grated, and there are specific techniques that should be used to grate wasabi rhizomes to bring out the fullness of the flavour. True grated wasabi should be of a natural pale greenish color rather than the brighter green normally associated with sushi restaurant wasabi.
Traditionally, wasabi rhizome is used as a condiment with sushi, although their leaves can also be used in salad dressings and or as a delicacy pickled in soy sauce or sake brine. The genuine vegetable is difficult to cultivate which explains why ordinary horseradish is dyed and used in its stead, and the vast majority of non-Japanese do not know the difference because it is likely to be all they have consumed under the name of wasabi. The health benefits of the genuine article, however, are considerable greater.
So that’s what it is, but what does it do? What are the health benefits of wasabi rhizomes and why are they considered to be so good for your liver? Wasabi rhizomes contain substances that are very effective in detoxifying you liver, and that are also very strong antioxidants that provide you with good overall health benefits in their capacity to destroy the free radicals created by the pollution of modern living.
The active antioxidants in the rhizome are precursors of isothiocyanates, which are known as phytochemicals. These are chemicals that can protect or prevent diseases through its antioxidant properties. The term ‘precursor’ means that the isothiocyanates are synthesized by your body from the nutrients contained in the wasabi rhizome. Other examples of phytochemicals that you may have heard of are carotenoids, flavonoids and polyphenols that also possess antioxidant properties.
Other antioxidants are vitamins A and E, which is why these are used in anti-wrinkle creams, since their anti-oxidant effect helps to prevent the free radicals destroying the skin cells in the dermis and epidermis that leads to the wrinkles associated with aging. Wasabi is equally effective as an antioxidant, although it has other properties that are important to your liver.
The liver is your body’s chemical plant. That is where most of the chemical reactions take place that are essential for life. If your liver is unhealthy you can develop diseases such as hepatitis and cirrhosis, and a healthy liver is essential for life let alone a healthy life. Wasabi helps to detoxify and clean out your liver.
Apart from creating the wide variety of enzymes needed to process your food, and controlling the vast majority of the biochemistry of your body, your liver is also your detoxification plant that coverts toxins into biodegradable molecules that your waste disposal system can evacuate without harm. This occurs in two phases.
Phase I coverts the toxin to a form that your body can further process (the Bioactive form), and Phase II breaks it down into a form that your kidneys can handle and eject it in your urine. Isothiocyanates are involved in the production of the enzymes that enable the chemical reactions of Phase II to proceed. They allow your body to cleanse itself of toxins, and without this process you would be less healthy and more prone to cancers and other undesirable conditions and diseases in your body.
It is becoming more important in this modern age with its increasing natural and synthetic pollution that your liver is working at peak efficiency. Your liver is equally as important to you as your heart and brain, and without it you cannot survive. Wasabi also contains glucosinolates that help the isothiocyanates to induce the production of Phase II enzymes, and it is general believed that eating this tuber cab help protect you against stomach, colon and breast cancers as well as help your cardiovascular system and blood clotting.
An interesting fact is how wasabi rhizome came to be traditionally served with raw fish. The isothiocyanates precursors, and the glucosinolates that wasabi also contains, apparently help to destroy the bacteria associated with raw fish, and help prevent disease and illness. It was likely found healthier to include a dollop of this green paste with your sushi than not, and so the use of common horseradish might be somewhat questionable if it has less of an effect.
Make sure, therefore, that your have the real thing, and apart from any specific health considerations associated with eating raw fish, you are best advised to take it as a supplement to help Detox your liver rather than visit sushi bars for your consumption. It will also help your wallet!
ActiFruit with Cran-Max – Cleanse, Purify, and Protect the Urinary Tract*
July 06, 2007 02:12 PM
One per day
1 Stothers L. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women. Can J Urol. 2002;9:1558-62.
2 wheeler R Cran-Max for the treatment of chronic urinary tract infections. Data unpublished. Abstract available at http://www.cranmax.com/studies_wheeler.shtml. 1998.
Complete Liver Cleanse
April 19, 2007 04:17 PM
Complete Liver Cleanse
Technical Data Sheet
The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day.
One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification.
Complete Liver Cleanse:
Includes ingredients for various aspects of liver and gallbladder support:
-Herbal ingredients that support liver and gallbladder health
-Detoxifying ingredients that keep bound toxins from being reabsorbed
-Phytosterols to block cholesterol absorption in the intestines
-Fiber that moves cholesterol and toxins out of the body
-Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan
-Simple, two week liver cleanse program
Each 3 capsules contain:
Calcium (as calcium D-glucarate) 13 mg
Proprietary PuraFiber Blend: 1 mg
Viscofiber Oat B-Gucan Concentrate, phytosterols
(beta sitosterol, campesterol, stigmasterol, brassicasterol,
and other plant sterols), and glucomannan
Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg
One part Milk Thistle Extract, standardized to contain 80%
Silymarin bound to two parts phosphatidylcholine (soy) using
a patented process
Burdock (Arctium lappa) Root Extract 4:1 100 mg
Calcium D-Glucarate 100 mg
Boldo (Peumus boldus) Leaf Extract 2:1 75 mg
Turmeric (Curcuma longa) Rhizome Extract 50 mg
Standardized to contain 90% curcuminoids
Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg
Artichoke (Cynara scolymus) Leaf Extract 30 mg
Standardized to contain 13-18% caffeylquinic
Acids calculated as chlorogenic acid
Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal.
Other ingredients: See label for most current information
Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the
This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by
HOW DOES IT WORK?
Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions.
Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon.
Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide.
The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American.
Herbal Liver Support
One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% silymarin, the plant’s most Bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract.
Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification.
Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes.
A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, phosphatidylcholine is an important building block of cell membranes.
When milk thistle (or other herbs) are bound with phosphatidylcholine, the phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comparison to the individual herb alone.
To test whether binding an herb with phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system.
Other Herbal Liver Supportive Ingredients
Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits.
For instance, dandelion root extract supports healthy bile flow from the gallbladder.
Burdock is originally native to Europe and Asia, but was introduced to
Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines.
Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern
In scientific studies, boldo appears to have strong free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time.
Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated.
Turmeric (Curcuma longa) is a perennial shrub native to southern
More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function.
In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits.
Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function.
The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile.
However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted.
Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges.
Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body.
Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder.
Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells.
High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health.
LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day).
One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils.
The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy.
Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines.
The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system.
Fiber and detoxification
Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts.
Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA.
SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health.
Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan.
Konjac, (Amorphophallus Konjac) is a tuber native to
As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid.
Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits.
In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial.
Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion.
Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber.
Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit.
Three capsules in the morning and three capsules at bedtime for 14 days.
Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.
Mangoni - Complete SuperFruit Food 1oz equals 3 servings of Vegetables
December 27, 2006 12:26 PM
Pycnogenol: Heart, Blood Sugar and Cellular Health
November 03, 2006 12:16 PM
Pycnogenol (pronounced pic-nojen-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France. Pycnogenol® consists of particularly Bioactive flavonoid species and its purity is in strict accordance with the United States Pharmacopoeia. Pycnogenol® was initially developed 35 years ago in Europe. During the past years it evolved as one of the most thoroughly researched nutritional supplements, with over 200 studies published in peer-reviewed journals. Seventy of these studies were clinical with in total more than 4,000 patients. Pycnogenol® taken in dosages from 25mg to 300mg is well tolerated and Pycnogenol® was attributed “generally recognized as safe” (GRAS) by the FDA.
Pycnogenol® supports healthy capillaries
The “Career” of Pycnogenol® began in Europe, where it was first used to maintain vein and capillary health. Pycnogenol® has been shown to strengthen blood vessel walls, with 15 clinical trials showing fast relief from ankle and foot discomfort. A recent study with 200 passengers on long-haul flights showed that Pycnogenol® taken before departure and again during the flight supports foot comfort and healthy circulation. Travelers typically comment that with Pycnogenol® it is much easier to put shoes on again upon arrival. Clinicians in Germany discovered that Pycnogenol® also supports healthy capillaries in the eyes. Retinal capillaries may be affected by imbalanced blood sugar levels. In a multi-center field study with 1169 subjects Pycnogenol® supported healthy capillaries in the retina and improved visual acuity to some extent.
Pycnogenol® benefits the cardiovascular system
More detailed investigation of the interaction of Pycnogenol® with blood vessel walls at the University of Florida, Tampa led to an amazing discovery. Pycnogenol® stimulates an enzyme in blood vessel walls that is responsible for generating the most important vascular mediator, known as “nitric oxide” (NO). NO triggers relaxation of the arteries and supports clear blood flow. Hence, NO is the body’s mediator for maintaining healthy blood pressure levels and circulation. NO plays such an important function for cardiovascular health that Dr. Louis Ignarro (UCLA) and his co-workers received the Nobel Prize for this discovery in 1987.
A number of factors, including aging, can interfere with the body’s efficient production of NO. Supplementation with Pycnogenol® for four weeks was shown to restore NO production and improve blood supply to the fingertips of elderly people in a Japanese study. Microscopic evaluation of blood vessel diameter at the root of fingernails showed an increased diameter of capillaries allowing better blood perfusion. Specific sensors applied to the legs showed increased oxygen and decreased carbon dioxide presence. Better blood, nutrient and oxygen supply with Pycnogenol® benefits everybody. Italian researchers were able to show that regular intake of Pycnogenol® helps defy muscle cramps and minor pain in athletes.
The relaxation of arteries has a favorable effect on blood pressure. In two clinical studies Pycnogenol® taken for at least eight weeks was found to significantly support normal blood pressure.
Pycnogenol® stimulated NO generation directly translates into clear blood flow. This was first demonstrated at the University of Arizona, Tucson in smokers. Pycnogenol® dose-dependently, starting at a single dose of 25mg, countered the typical effects of cigarette smoking on the blood. Also, Italian vascular specialists found that Pycnogenol® supported the circulation of individuals on flights between New York and London.
Pycnogenol® supports healthy blood sugar levels
Pycnogenol® can support normal glucose levels when taken as part of a healthy diet and lifestyle plan. A clinical investigation has confirmed the significant glucose-lowering effect of Pycnogenol®. It was noted that Pycnogenol® did not affect insulin levels. Pycnogenol® appears to facilitate previously insulin-resistant cells to uptake sugar from the blood stream by yet unknown mechanisms.
Pycnogenol® limits cellular irritation
Two clinical studies carried out in Germany this year with student volunteers demonstrated that Pycnogenol® has a potent effect in preventing cellular irritation. Pycnogenol® inhibits a molecular “main-switch” in immune cells that triggers the onset of cellular irritation in any part of the body. Moreover, Pycnogenol® was found to inhibit so-called COX enzymes, which are involved with minor pain-sensation related to cellular irritation.
Pycnogenol® sooths menstrual pain
Japanese gynecologists discovered in 1999 that regular supplementation with Pycnogenol® soothes the normal discomfort of menstrual pain, particularly during cramping. Another clinical investigation of 47 women in year 2004 confirmed the effect of Pycnogenol® in addressing menstrual pain. This year a double-blind, placebo-controlled, multi-center field study with 116 women again confirmed these results. Pycnogenol® is not suitable for on-demand relief during menstruation. The studies show that Pycnogenol® reached highest efficacy when taken regularly for months.
Pycnogenol® helps to support respiratory health
Challenges to normal respiratory function may result from incidents the immune system perceives as harmful. Pycnogenol® offers valuable help in supporting respiration due to its immune-modulating effect and its ability to limit cellular irritation. A study at the University of Arizona found that Pycnogenol® supports clear breathing and lowers mediators of cellular irritation in the blood stream. More recently, a placebo-controlled clinical study at the University of California, Loma Linda described how Pycnogenol® supported healthy respiration in 60 children aged 6-18 years. Pycnogenol® needs to be taken continuously for prolonged periods of time for maximum benefit to the respiratory system.
Pycnogenol® is investigated in clinical trials all over the world. New findings are posted on the website www.pycnogenol.com.
Frank Schonlau Ph.D. is a biochemist who has spent nine years in medical research at the University Clinic of Munster Germany. His area of expertise covers vascular disorders, inflammation and dermatology. He has published more than 20 studies and review articles in the medical literature. Since entering the dietary field in 1999 he was involved in numerous studies on Pycnogenol® and communication of new health discoveries.
Wasabi Rhizome Cleanse - Supports Phase II Liver Detoxification - Wasabi Health Benefits
August 01, 2006 10:41 AM
Most people know of it as a pale-green lump on the side of their plates in Japanese restaurants—a hot, spicy accompaniment to sushi or sashimi. The fiery yet sweet taste perfectly compliments the saltiness of soy sauce and the cool delicacy of raw fish. But wasabi is much more than a burst of culinary flavor, it has been used by traditional herbalists of Japan since the 10th century and is now being rediscovered by modern health practitioners for its stunning health benefits.
Wasabi has powerful detoxification properties, in particular, it supports the immune system and cleanses the liver. Wasabi contains precursors to phytochemicals called isothiocyanates that help remove toxic substances that are stored in the liver’s fatty tissues.
The rare wasabi plant is a natural, potent support to a healthy, cleansed liver that in turn affects the detoxification and cleansing of the entire body. Source Naturals is pleased to bring you this convenient, effective addition to your wellness program.
Wasabia Japonica - Rooted In Health
The wasabi plant (Wasabia japonica) grows naturally in the mountains of Japan in the gravel and sandbars of coldwater streams and rivers. Rare and difficult to grow, it takes three years for a wasabi root or rhizome to reach maturity. Because of its popularity, wasabi is now cultivated hydroponically and in cold, wet environments outside of Japan, such as in New Zealand and Oregon. Traditionally, the rhizome was freshly grated at the table with a sharkskin grater, popular with dishes such as seafood or udon noodles. Now wasabi is usually dried into powder form and made into the pale green paste familiar to most westerners. Often, however, restaurants do not serve real wasabi; since it is so rare and expensive, a dyed horseradish paste is served in most American restaurants.
What makes wasabi so special? It comes from a good family; the brassica vegetables in the cruciferae family include such health giants as broccoli, horseradish, Brussels sprouts, cabbage, cauliflower and kale. All of these are well-known detoxifying plants, and wasabi appears to be the most amazing of them all, with detox capacities far beyond the others in the family because it is loaded with isothiocyanate precursors. This chemical not only gives wasabi its famous “fire,” it is likewise a fireball of detoxification properties.
Phase II Detox
The liver detoxifies the by-products of digestion and other harmful substances through a complex series of chemical reactions often referred to as Phase I and Phase II Detoxification. Phase I enzymes begin the process by taking the toxic molecule and changing it into a Bioactive form. This process breaks down toxins. A second set of enzymes, Phase II, then neutralizes the toxin and makes it water soluble for elimination. Wasabi, with its long-chain isothiocyanate precursors, induces the Phase II enzymes. Simply stated, it is the sparkplug that starts Phase II enzymes on their work. This process, all done in the liver, supports the body’s ability to clean itself of impurities.
Part of a Complete Wellness Program
In the modern world, with so many pollutants, it is critical to your health and longevity that you cleanse these toxic compounds from your body. Wasabi, along with a whole food, high-fiber diet and reduction of alcohol consumption, supports the liver— the largest of the vital organs and the key to the digestion and elimination systems and most particularly, the body’s ability to cleanse itself. Source Naturals is pleased to bring you this exceptional product as part of your wellness program.
Depree, JA (1999) Flavour and pharmaceutical properties of the volatile sulphur compounds of Wasabia japonica. Food Research International: 31(5):329-337.
Morimitsu Y, et al. (2002) A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. J Biol Chem: 277:3456-3463.
Munday, R (2002) Selective induction of phase II enzymes in the urinary bladder of rats by allyl isothiocyanate, a compound derived from Brassica vegetables.
Nutrition and Cancer: 44(1):52-59.
Watanabe, M (2003) Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi. Phytochemistry: 62(5):733-739.
Rose, P (2000) 7-methylsulfinylheptyl and 8- methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis: 21(11):1983-1988.
A Testosterone Breakthrough to Restore Health and Youth
May 29, 2006 07:17 PM
There is a powerful new performance-enhancing ingredient clinically proven in humans. Its called LJ100 Tongkat Ali. Four years ago no one in the United States had heard of Tongkat Ali. Today the herb is becoming increasingly well-known as an athletic performance enhancer, overall youth-promoting agent, and libido builder.
Tongkat Ali is the popular folk name for Eurycoma Longifolia, a medium sized, slender rain forest tree. The name Tongkat Ali means Ali’s walking stick and the plant is native to Malaysia, lower burma, Thailand and Indonesia. Tongkat Ali enjoys a history of use that dates back to the 1700’s, and today there is a growing body of serious science that corroborates its traditional uses, specifically for the patented and proprietary brand LJ100 Tongkat Ali standardized extract containing 28% Bioactive glycopeptides.
LJ100 Tongkat Ali
LJ100 is a proprietary, patented ingredient, and has become recognized as the premier brand of Eurycoma Longifolia for supplements that build and tone muscles, boost energy levels, decrease body fat, slow the aging process, and increase libido for health-conscious consumers. LJ100 has undergone an exclusive, patented extraction process to capture the most potent, biologically active compounds. SourceOne Global Partners, headquarters in Chicago, holds the exclusive distribution rights to market and sell LJ100 Tongkat Ali in dietary supplements.
ATP and Lean Muscle
In studies, LJ100 Tongkat Ali extract greatly increases ATP production. ATP, or adenosine triphosphate, is the basic unit of energy in the body, responsible for keeping us alive and going. By increasing ATP, overall energy and vitality are increased. Most people seek more energy and LJ100 Tongkat Ali provides it, without hyper stimulation, jittery nerves or insomnia. Promoting human energy production is a valuable health benefit by itself to make LJ100 Tongkat Ali an enduring botanical superstar. People want energy more than just about any other functional attribute.
Endocrinologists have known for a long time that testosterone increases the body’s ratio of lean muscle mass to fat. In both animals and humans, LJ100 Tongkat Ali increases muscle mass. In a study of men, half the subjects ingested LJ100 and half did not. In an eight-week physical training program the men who consumed LJ100 experienced greater gains in muscle mass and strength than those that did not. This demonstrates the powerful anabolic properties of Tongkat Ali. Instead of turning to the use of dangerous and potentially lethal steroids, it is recommended that more athletes opt for Tongkat Ali. In Malaysia, many professional field hockey players use LJ100 Tongkat Ali as an androgen and swear to its performance-enhancing effects. According to Chris Kilham, ethno botanist, author and lecturer, in a recent article in Physical Magazine,. “LJ100 Tongkat Ali has potential to revolutionize the sport nutrition category.”
Maintaining Normal cortisol / Testosterone Ratios
LJ100 is clinically proven to enhance weight loss and maintain high energy levels by maintaining normal levels of cortisol and testosterone during weight loss. More particularly, LJ100 studies have shown it to help maintain normal (low) cortisol and normal (high) testosterone levels during the stress of weight loss. This hormonal control provides energy to a person in a weight loss phase while simultaneously helping them lose weight. As a result, effective doses of LJ100 help prevent the body from seeking to gain weight by storing fat and increasing appetite. LJ100 can help stop the “yo-yo” diet effect where a dieter’s initial weight loss of a few pounds sends the body into catabolic state, leading to binge eating and fat storage.
LJ100’s Testosterone Breakthrough
LJ100 Tongkat Ali root contains numerous beneficial compounds, including potent protective antioxidants which inhibit cellular aging. What excites many people about LJ100 Tongkat Ali is that the root significantly boosts libido in men and women by increasing testosterone. Agents identified as glycoproteins are now proven to be the libido boosting ingredients in the plant.
Increasing testosterone is the key factor is the key factor in increasing libido. Testosterone is the most important of the male sex hormones, known as androgens, produced in the gonads. Testosterone plays a key role in the development and maturity of male sex organs. The hormone promotes secondary sex characteristics, including appearance of facial hair, enlargement of the larynx (producing a deeper voice), sexual desire and sexual behavior. Testosterone also stimulates metabolism, promotes lipolysis (Burning of fat), increases the formation of red blood cells and accelerates muscle growth.
Testosterone doesn’t stay with us from age 30 or so, blood levels of this hormone decline at a rate of about 2 percent per year. By age 50, the level is around 55 percent. As testosterone decreases, muscle tone, energy and sex drive all begin to decline. But testosterone is not just for men. The same decline in testosterone occurs in women, though the amounts involved are lower. In both sexes, sex drive, function, fat metabolism and energy decline into middle age.
One of the questions that many health researchers have pondered is what if you could boost your testosterone levels to more youthful levels? With LJ100 Tongkat Ali extract you can. And that makes LJ100 are true fountain of youth.
LJ100 Tongkat Ali “is the Greatest”
Don’t be fooled by wannabes. Only LJ100 delivers efficacy, standardization and supporting scientific research. When compared against lesser quality products, research showed LJ100 to increase serum testosterone levels 100% after two weeks, while some other products showed only an 8% improvement in serum testosterone level. Ali is the greatest only if it is LJ100 TongKat Ali.
Dr. Zheng-Xian Liu, PhD, has more than 18 years of experience in the Nutraceutical business and more than 34 years of experience in R & D. he received a doctorate of biochemistry and nutrition at Virginia Polytechnic Institute and State University. He was an NIH post-doctorate research fellow at Duke University Medical Center, specializing in free radical biochemistry, and a Pratt research fellow in nutrition. He also served as a member of the editorial board of journal of Advancement in Medicine and has published more than 60 papers in peer-reviewed scientific journals.
HAWAIIAN NONI (Morinda citrifolia)
July 11, 2005 08:50 PM
In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:
Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.
The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.
Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.
Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.
discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.
ROOT AND ROOT BARK
Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.
Body Systems Targeted
The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.
Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.
Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .
NONI: ITS USE AND HISTORY
Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .
Wonder Herb of Island Folk Healers
Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.
Noni’s Medical Reputation
Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.
A Timely Reemer gence
Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.
TRADITIONAL USES OF NONI
Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15
decoctions to stimulate delayed menst ruation.
XERONINE: THE SECRET OF NONI?
One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .
Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18
How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.
MODERN APPLICATIONS OF NONI
Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.
Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.
xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.
A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21
In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.
with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.
The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.
The Bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.
The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.
While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.
A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29
Skin Healing Agent
One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.
burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30
The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.
Complementary Agents of Noni
PrimaryApplications of Noni
Cinnamon may control sugar levels...
July 08, 2005 10:48 AM
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11. Duke, JA. Handbook of Phytochemical
12. Botanical Safety Handbook. American
Acting as a biochemical
Supports Healthy Blood Sugar Levels-Herbally
July 05, 2005 10:18 AM
The introduction of refined sugars into the modern diet has had tremendous negative health consequences on world health. For example, diabetes, especially insulin-independent diabetes (Type 2), is growing rapidly in the United States particularly among children. This type is partly due to the inability of insulin to effectively transport sugar to receptor sites and into cells, where the sugar can be metabolized. Instead of being "burned up," sugar builds in the blood, creating a potentially serious health problem. This inefficiency can occur for a number of reasons, including: insufficient insulin production due to pancreas dysfunction (though many Type 2 diabetics produce excess insulin); the inability of insulin to carry sugar to receptor sites; a defect in the insulin; or a defect in the receptor that does not allow for the sugar to be transported through the cell membrane. Even if one does not have diabetes, it is important to maintain healthy blood sugar levels through proper diet, exercise, and weight management. This is especially important in children who were recently found to obtain 14% of their daily calories from sweet drinks (sodas), overtaking white bread as the primary source of total daily caloric intake. Regardless of the reason, a number of botanicals, in addition to key lifestyle recommendations, have been shown in modern research to support healthy blood sugar levels by enhance sugar metabolization. (Cinnamomum aromaticum syn. C. cassia*) is one botanical that has been shown to have a positive effect on potentiating the effects of insulin.
*The study referrd to the material used as Cinnamomum cassia. The officially accepted botanical nomenclature has changed and is now Cinnamomum aromaticum.
Spices have been used historically to increase metabolism, raise body heat (thermogenesis), improve digestion and assimilation, and potentiate the effects of other substances. For this reason, in many herbal traditions, small amounts of hot pungent spices were added to many traditional compounds. Regarding sugar metabolization, a study by the United States Department of Agriculture (USDA) looked at the potential effects of 49 spices on insulin function (Broadhurst et al. 2000). These researchers found that cinnamon was the most Bioactive in directly stimulating cellular glucose metablosim, i.e. the ability of cells to utilize sugar. The same researchers followed up with constituent studies and determined that it was water-soluble compunds in the extract that had this insulin-potentiating effect. This was followed by a clinical trial (60 subjects), also with involvement of the USDA, on the effects of cinnamon for potentiating insulin. The equivalent of 1, 3, and 6 grams (g) of cinnamon powder (approximately 1/4 to 1.5 teaspoons) reduced blood glucose levels 18-29% in 40 days (Khan et al. 2003).
There was a significant increase in efficency between the 1 and 3 g doses, but an insignificant increase between the 3 and 6 g doses. One mechanism of action that has been postulated is that cinnamon increases the activity of PI-3 kinase, an enzyme that is critical in regulating the ability of glucose to be transported into the cell, where it can be utilized as energy. In addition to its ability to potentiate insulin, the cinnamon also supported healthy triglyceride and cholesterol levels, both important health benefits in general.
There is an additional benefit of using cinnamon for many Americans; like many spices it is a potent thermogenic agent. This means it can be used as a healthy adjunct to a weight loss program that includes dietary modification and proper exercise. The excessive consumption of simple sugars in conjunction with poor diet and sedentary lifestyles can cause unhealthy blood sugar levels while providing themogenic support can have long-lasting health benefits.
There have been a number of popular articles on the recent studies. This had led some to ask if crude cinnamon powder can be used with the same effect and safety. This has not been tested. As with all spices, cinnamon is rich in essential oils. Essential oils have beneficial effects, but the insulin-potentiating effect was found to occur in the water extract. This would suggest that many of the oil soluble compunds were lost in the processing. Also, essential oils can be stimulating and irritating, one of the reasons they are generally used in small amounts as flavoring agents. Therefore, it would be best to look for products that contain the water extract to ensure you are delivering the preparation that most closely reflects the preparation used in the studies.
Maintaining healthy weight and increasing lean body mass are key components in the supporting healthy blood sugar levels. Recently it was reported that only two days of inactivity resulted in a decreased level of insulin sensitivity. Therefore, supporting healthy blood sugar levels is extremely important for those wanting to maintain a healthy lifestyle. In obesity, or in those with a significantly higher percentage of body fat over lean muscle (body mass index greater that 25), it is very difficult for insulin to do its job effectively. The reason is quite simple: fat cells can prevent insulin from actually reaching insulin receptor sites; the fat physically blocks the receptor, and the sugar that should have been burned off through cellular function remains in the blood. It is important to know that, in such cases, there is often nothing at all wrong with the pancreas (the insulin-producing organ), the insulin, or the receptor sites. The fat simply prevents insulin and sugar from reaching their target. In many cases, people are over-producing insulin in an attempt to get more sugar to the receptor sites. After awhile, the pancreas can become exhausted and no longer produce adequate amounts of insulin. Therefore, a primary therapy for supporting healthy blood sugar levels is proper weight management through diet and exercise.
Broadhurst CL, Polansky MM, Anderson RA. 2000. Insulin-like biological activity of culinary and medicinal plant extracts in vitro. J agric Good Chem. 48(3):849-852. Khan A, Safdar M, Khan M, Khan K, Anderson R. 2003. Cinnamon improves glucose and lipids of people with Type 2 diabetes. Diabetes Care 26912):3215-3218.
Roy Upton is trained in Western and traditional Chinese herbalism, and has been a professional herbalist for 18 years. He is past president and current vice-president of the American Herbalists Guild (AHG) and is also executive director and editor of the American Herbal Pharnacopoeia. an organization dedicated to the development of authoritative monographs on botanicals used in supplements and medicines. Roy is general manager of Planetary Formulas and a memeber of the Standards Committee of the American Herbal Products Association. He is the author of several books, including St. John's Wort and Echinacea in the Keats Publishing Good Herb Series and co-author of the Botancial Safety Handbook, published by CRC Press. Roy lectures and writes extensively.
Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Life Force - The Energy Activator
June 29, 2005 10:35 AM
Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%
We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.
Bio-Align™ Yourself with Life Force
LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.
Get Ahead with Activated Energy and a Healthy Metabolism
Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.
LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.
Protect Your Heart and Circulatory System
The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.
Skin and Musculoskeletal Support
LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.
Brain and Nerves Nutrition
The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and Bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.
LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.
Powerful Liver Support
Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.
Complete Antioxidant Defense
Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.
Cutting-Edge Vision Nutrition
The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.
Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle
LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.
Support Healthy Fat and Protein Consumption with Life Force
Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.
Complete Energizing Nutrition
LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!
Promilin Fenugreek Extract - Supports Healthy Blood Sugar Levels
June 28, 2005 10:44 AM
.. Your body’s ability to manage blood sugar may well be the single most crucial factor affecting your health and longevity, and the one most affected by diet and lifestyle. But today’s high-glycemic carbs and sugar-laden foods — combined with lack of exercise — are creating a serious challenge to your body’s intricate glucose/insulin regulatory system. The resulting cellular stress and deterioration have serious repercussions for both your mind and body. To promote optimal wellness through healthy sugar metabolism, Source Naturals formulated PROMILIN™ FENUGREEK EXTRACT, a potent extract from the highly valued herb fenugreek, into an advanced nutritional supplement designed to assist insulin production and support healthy glucose levels. As a complement to your diet, Source Naturals PROMILIN™ FENUGREEK EXTRACT is an excellent strategy to improve blood sugar levels, and consequently, quality of life.
The basis of Source Naturals PROMILIN™ FENUGREEK EXTRACT is fenugreek (Trigonella foenum-graecum), a respected culinary and medicinal herb used throughout history. One of the formula’s fenugreek extracts is rich in galactomannan, a mucilaginous fiber that may benefit the bowel. The other extract is Promilin, a patent-pending complex of Bioactive amino acids standardized to contain 20% 4-hydroxyisoleucine. This extraordinary amino acid derivative assists the pancreas in production of insulin. Several studies with animals and with human cell cultures demonstrate this extract’s positive effect on reducing post-meal glucose levels — with little or no increase in blood insulin concentrations — a clear indicator of improved insulin sensitivity.
Athletic energy and endurance depend on the ability of muscles to recover from exercise. Because PROMILIN promotes utilization of glucose and insulin by the the body’s muscle cells, “weekend warriors” will feel less fatigue on Monday morning. In a clinical study, PROMILIN increased glycogen re-synthesis by 63% over carbohydrate alone. This is the rate at which post-exercise muscle glycogen (energy) is restored. PROMILIN may also play a role in weight management because it helps your body metabolize carbohydrates more efficiently. And the less time glucose spends in your bloodstream, the less chance it will be converted into fat. By supporting glucose metabolism, Source Naturals PROMILIN™ FENUGREEK EXTRACT may help protect against a harmful process called glycation, where excess glucose reacts with amino acids to form crosslinked sugardamaged proteins that damage the linings of blood vessels, the lens of the eye, and the myelin sheath that insulates brain cells.
Probiotics - Our Friendly Bacteria
June 16, 2005 10:51 AM
An estimated 10 quadrillion bacteria make their home in the average digestive system. Fortunately, less than one percent of the 400 different species found in the intestine are potentially harmful. The majority of intestinal flora are friendly bacteria, otherwise known as probiotics. These probiotic bacteria support good health by limiting the growth of harmful bacteria, promoting good digestion and increasing resistance to infection.*1
Probiotic bacteria are completely non-toxic. In fact, friendly bacteria have been used safely and effectively for more than 8,000 years, proving their value to human health.*2 Most often, probiotics have been consumed as part of cultured foods, such as acidophilus milk, yogurt, soy tempeh, and idli (cultured wheat). The friendly bacteria in these foods, specifically Lactobacillus acidophilus, L. bulgaricus, and Bifidobacterium bifidum, multiply in the warm, moist environment of the human body by feeding on the carbohydrates and protein in the digestive tract, then establish colonies along the intestinal wall.
Beneficial Roles of Probiotics
Lactobacillus acidophilus and other friendly bacteria play many important roles in maintaining good health.* According to experts, regular consumption of probiotics is the best way to maintain healthy intestinal flora.*3, 4 Lactobacilli species do not survive very long in the colon, so bacteria colonies need to be routinely replenished.*
In addition to producing numerous vitamins, probiotics support healthy digestion.* Part of the reason fermented foods are healthful is that some of the proteins, fats and carbohydrates are partially digested by the bacteria, which increases overall digestibility and nutritional value of the food.*5, 6
Lactose intolerant individuals may gain even more benefits from probiotics. Lactobacilli bacteria ferment as much as half of the lactose in milk—the part of milk that results in the symptoms of bloating, cramps and gas in lactose intolerant individuals—by converting it to lactic acid. Consequently, people with lactose intolerance report fewer digestive problems with cultured dairy foods compared to fresh milk.*5, 7
The nutritional profile of foods is improved after being cultured with probiotics. Levels of several B vitamins, including vitamins B1, B2, B6 and B12, niacin, folic acid and pantothenic acid are higher in fermented foods, such as yogurt, cheese, kefir and buttermilk.*5 Fermentation also boosts the digestibility of soy foods.*8
Inhibiting bacterial growth:
Probiotics act as natural antibiotics, slowing the growth of harmful bacteria.*5, 6 These friendly bacteria produce substances, including lactic acid, acetic acid, benzoic acid, hydrogen peroxide and natural antibiotics, which limit the reproduction of certain disease-causing bacteria.*9
Another way that probiotic bacteria maintain a healthy digestive tract is by competing with harmful bacteria in the intestine. When the intestine is full of large colonies of beneficial bacteria, disease-causing bacteria are simply not able to multiply into harmful numbers because there are no available attachment sites on the intestinal wall.* This is one of the ways L. acidophilus inhibits the growth of Candida albicans, coliform (e. coli) bacteria and salmonella.*3, 4, 10, 11
Diarrhea can have many causes, but it always has the same result for the bacteria living in the intestine—it flushes them out, leaving the body vulnerable to the growth of opportunistic bacteria. It is important to replenish the body with probiotics during and after a bout of diarrhea.* Probiotic bacteria can also help keep the colon healthy when traveling.*4
Lactobacilli are one of the primary bacteria found in normal vaginal flora, and their presence is believed to inhibit the overgrowth of harmful bacteria, such as Candida. Lactobacillus acidophilus cultures are a popular folk remedy for vaginal health.*4, 10
Recolonization After Antibiotic Use:
Antibiotics, given to treat bacterial infections, ironically can contribute to unhealthy bacteria growth. Antibiotics destroy bacteria, the good along with the bad, leaving the intestine without its normal, healthful flora. In this compromised state, disease-causing bacteria can multiply unchecked by friendly bacteria.*12 When ingested during and following antibiotic usage, L. acidophilus rapidly restores normal flora, shortening the time that undesirable organisms remain in the gut.*3, 12 Bifidobacterium bifidum can also help normalize the intestinal flora after using antibiotics.*10
Producing the Best Probiotics
Fermenting foods with lactobacilli has been a time-honored method for both preserving and enhancing foods. Before refrigeration, fermentation was a valuable way to preserve food safety, and it remains in common usage today.
Nature’s Life uses the same basic principles developed and perfected by prehistoric nomadic peoples to produce Lactobacillus acidophilus products; with the exception that we use modern, high-volume equipment. These improvements, along with trained personnel, scientific methods and quality assurance practices, ensures that every batch meets our high standards of quality.
Our lactobacilli are cultured on nutrient-dense food concentrates, such as soy protein, green peas or non-fat milk. We add natural apple juice, pasteurized clover honey, strawberries, carrot juice or maltodextrin for flavor and to provide carbohydrates for the micro-organisms, plus we use only pasteurized water.
Our growth medium has a broad range of vitamins, minerals, enzymes, amino acids, essential fatty acids, organic acids and naturally occurring plant phytonutrients such as flavonoids and carotenoids with beneficial antioxidant properties. The temperature and moisture are carefully controlled during the several days needed for the bacteria to multiply to peak potency.
At the peak of potency, Nature’s Life Liquid Acidophilus culture is poured directly into sanitized 16 oz. glass bottles and immediately refrigerated at 36°F to maintain peak potency. These liquid products are the most Bioactive of all forms of acidophilus because they are dormant, rather than frozen.
For our freeze-dried powders and capsules, the warm liquid culture is immediately poured into containers, sealed and refrigerated. After cooling, the liquid is poured into trays and instantly freeze-dried. The frozen lactobacillus is then processed through a vacuum freezer to lower the moisture level to an absolute minimum. This freeze-dried product is packaged as either powder or capsules. When swallowed, the microorganisms will rehydrate and begin colonizing the gastrointestinal tract with friendly bacteria.
Nature’s Life acidophilus is not filtered, centrifuged or otherwise concentrated or separated from its growth medium to artificially obtain higher concentrations of bacteria per gram or capsule. Centrifuging may damage the lactobacillus by altering the natural clumping, chaining and branching of bacteria cells.*
Nature’s Life probiotic products retain all the benefits of the nutrient-rich growth medium. All the valuable by-products of the bacteria’s metabolism remain in the final product, including B-vitamins, enzymes, organic acids, antibodies and even naturally occurring antibiotics. The conclusion of experts is that products which are centrifuged or filtered are incomplete.13 14
Quality You Can Trust
Nature’s Life invests significant resources in perfecting the production of high quality Lactobacillus acidophilus cultures. You benefit from our knowledge and experience every time you choose our supplements.
Nature’s Life lactobacillus cultures are manufactured with rigorous specifications using state-of-the-art equipment. All equipment and containers are sanitized to ensure that no contaminants or unfriendly pathogenic bacteria corrupt the quality of the L. acidophilus. The large capacity fermentation tanks and freeze dryers maintain consistency in each batch.
Nature’s Life Lactobacillus acidophilus meets or exceeds all standards developed by industry associations and government regulations. These standards, established to determine the quality of the finished product, are:
All of Nature’s Life Lactobacillus acidophilus products meet the acid test for effectiveness:
Using Nature’s Life Probiotics
Nature’s Life probiotics, such as Lactobacillus acidophilus, L. bulgaricus and Bifidobacterium bifidum, can survive in the stomach for at least an hour.*15 Nature’s Life recommends taking probiotics either on an empty stomach or with food, however the presence of food can help the organisms stay alive longer.16
Liquid acidophilus should be treated as a perishable product, since it contains live, active organisms. Like yogurt or milk, acidophilus should be refrigerated and used within a short period of time. Contact Nature’s Life for a recipe on how to make your own soy-based, milk-free yogurt.
VITAMIN A and CAROTENOIDS - What are they good for?
June 09, 2005 09:27 AM
In 1912, Casimir Funk coined the term 'vitamine' to refer to a 'vital factor' he proposed was an essential component present in foods. His conjecture dovetailed with other research, leading to the isolation in the 1930's and 40's of the compounds we now call vitamins.
Vitamins are chemical substances which play a variety of roles in the human body. They are core components of any nutritional supplementation program.
While many people are aware of vitamins as necessary substances for good nutrition, few have a grasp of the extraordinary complexity of the roles they play in our bodies. As you'll see below, vitamins are involved in trillions of biochemical interactions every minute to keep us alive and functioning. For example, B-vitamins are converted into coenzymes which are directly necessary for the production of ATP energy from food, a process that goes on continuously in every cell in the body and which in turn fuels myriad physiological events such as muscle contraction, brain activity or tissue repair.
Source Naturals offers a full line of vitamins in Bioactive forms, allowing you to tailor a nutritional supplementation plan to your individual needs.
VITAMIN A and CAROTENOIDS
Vitamin A is a generic term for a class of fat-soluble substances called retinoids, which can either be consumed preformed or synthesized by the liver from plant pigments called carotenoids (see 'Carotenoids', below). An essential nutrient, vitamin A is perhaps best known for its role in vision.
The outer segments of the rods, a type of light-sensitive cell in the retina of the eye, contain a pigment called rhodopsin (or 'visual purple') that mediates vision in dim light. Cone cells mediate color vision via three additional pigments. Both rods and cones are surrounded by pigmented epithelial cells that store vitamin A. Rhodopsin is formed from a protein called opsin and a vitamin A-dependent compound called 11-cis retinal. As light strikes the rods and cones it is absorbed by the pigment molecules, and retinal is split off from opsin. This chemical change allows an electrical impulse to be sent to the optic nerve and thus to the brain. The pigment must then be regenerated from opsin and retinal. Repeated small losses of retinal during this process require a constant replenishment of vitamin A to the eyes.
Vitamin A also plays an extremely important role in epithelial cell differentiation. Cell differentiation is the process by which a cell undergoes a change to a specialized cell type, allowing it to perform particular functions in the body. It is not yet understood precisely how vitamin A is involved in this process. One hypothesis is that it directly affects gene expression through its interaction with chromatin, a complex of DNA, RNA and protein in the cell nucleus. These interactions affect the process of transcription of DNA to messenger RNA, leading to synthesis of a specific group of cellular proteins.
Each one of us carries in our DNA a unique genetic blueprint. This genetic material is the same in every cell of our bodies. It is only because of this mysterious and magical process of differentiation that we have specialized cell types - and therefore eyes, ears, lungs and hearts.
Vitamin A is necessary, either directly or indirectly, for the healthy growth and functioning of many of our tissues and organ systems, including the eyes, the skin, the bones, the reproductive system, and the natural defenses. It is not yet known whether this requirement is due to the role of vitamin A in cell differentiation or whether there are other physiological processes for which vitamin A is essential.
Vitamin A is related to a class of nutrients called carotenoids, including alpha and beta carotene, lycopene and lutein. Carotenoids are botanical pigments whose colors range from red to orange to yellow. Some carotenoids, particularly beta carotene, can be converted into vitamin A predominantly in the intestinal mucosa and to some extent in the liver. Carotenoids are completely non-toxic; their conversion into vitamin A is well-regulated by the body, making them extremely safe sources of this essential nutrient.
In addition to their role as safe sources of vitamin A, carotenoids are powerful nutrients in their own right. Their primary claim to fame is their powerful antioxidant action, particularly against singlet oxygen. Singlet oxygen is an 'excited' ion of oxygen which, while not technically a free radical, is nonetheless highly reactive. It causes 'oxidative' reactions which can impair or destroy membranes, enzymes and DNA. It can also lead to the formation of free radicals which can cause additional damage.
Certain carotenoids such as beta carotene, because of their chemical structure, can neutralize singlet oxygen by absorbing its extra energy and dissipating it throughout the carotenoid molecule, releasing the energy as heat and converting the singlet oxygen back to 'normal' oxygen. One molecule of beta carotene can quench up to 1000 molecules of singlet oxygen.
In addition to their role as singlet oxygen quenchers, carotenes provide antioxidant protection against free radicals as well. In nature, they protect plants from photo-oxidative reactions; in humans, certain carotenoids, notably beta carotene, may help protect the skin from such reactions. Other carotenoids may provide more localized protection to particular organs. Lutein and zeaxanthin, for example, are selectively concentrated in the retina of the eye. Along with vitamins C and E, carotenes are among the most important nutrient antioxidants in the human body.
OptiZinc - The king of Zinc ...
June 04, 2005 10:43 AM
Source Naturals brings you yet another breakthrough in mineral nutrition: OptiZinc! Opti Zinc is Zinc Monomethionine — Zinc combined with the essential amino acid Methionine. It is FDA approved as safe for human nutrition, and is so unique, it’s patented.
Opti Zinc — THE MOST POTENT FORM OF ZINC AVAILABLE Extensive scientific research shows that Opti Zinc is the most bioavailable and Bioactive form of Zinc tested.1 Aside from demonstrating superior absorption and utilization by the body for Zinc’s many functions, Opti zinc is also more efficient than other forms of Zinc in getting needed Vitamin A out of storage in the liver, thus making it available for use.2 Perhaps most outstanding is the synergy offered by this combination of Zinc and Methionine: while both of these nutrients are well-known for their freeradical- neutralizing properties, the antioxidant activity of Opti Zinc far surpasses that of either Zinc or Methionine alone. ZINC — ESSENTIAL
FOR YOUR HEALTH
Zinc is one of the most important minerals your body uses. Among its many functions, Zinc is: ? critical for the health of the thymus gland, which is necessary for the natural defenses, as demonstrated in recent research by Nicola Fabris, Ph.D., director of the Gerontology Research Department of the Italian National Research Center on Aging in Ancona, Italy;3
DO YOU GET ENOUGH ZINC IN YOUR DIET?
As vital as Zinc is, it can be hard to get enough of, even when following a healthy diet. Surveys show that the daily intake of Zinc in the average American diet ranges from 8 to 11 mg, yet the U.S. RDA is 15 mg. The few excellent sources include seafoods (such as oysters, herring, and clams), whole oatmeal, wheat germ, wheat bran, and milk.4 If some of these are not a regular part of your diet, you may be one of many people who are Zinc deficient, and you may want to use a dietary supplement.
SOURCE NATURALS™ — Opti Zinc THE SUPPLEMENT OF CHOICE One Source Naturals’ Opti Zinc tablet provides 30 mg of Zinc (from 150 mg Opti Zinc Zinc Monomethionine), which is 200% of the U.S. RDA for Zinc. 300 mcg of the essential mineral Copper is also included, to offset the displacement of Copper that can occur when high levels of Zinc are consumed. The form of Copper used is also state-of-the-art: it is Copper Sebacate, a natural compound that is Copper:SOD-mimetic, meaning that even on its own, it can act as an antioxidant. Its inclusion with Zinc Monomethionine makes Source Naturals’ OptiZinc a powerful antioxidant combination that is truly on the cutting edge of nutrition science.
OPTI ZINC® brand of Zinc Monomethionine complex is a trademark of InterHealth Company; U.S. Patents Nos. 3,941,818, 4,021,569, & 4,764,633. Source Naturals’ OPTI ZINC® is all-Vegetarian and hypoallergenic: contains no yeast, dairy, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.
Mushroom Immune Defense - Scientific Immunity Formula
June 04, 2005 10:08 AM
The immune system is a fascinating and complex group of cells and biochemical processes. Its many components work to protect you from environmental threats—but your immune system requires nutritional support to function optimally. Scientific research is proving that some of the most powerful immune-supportive nutrients are found in mushrooms. People who realize the critical importance of optimizing immune function should seriously consider adding an advanced mushroom complex to their daily regimen. No other mushroom formula offers the high-potency, broad-spectrum benefits of Source Naturals MUSHROOM IMMUNE DEFENSE. MUSHROOM IMMUNE DEFENSE features 16 of the best-studied species of health-supportive mushrooms, including shiitake, reishi, and maitake. These mushrooms contain compounds, including beta-glucans, glycoproteins and polysaccharides, that support a wide range of immune defenses: natural killer cell, T-cell and macrophage activity, and cytokine production. By combining a wide variety of mushrooms and fortifying them with extracts to ensure high potency, MUSHROOM IMMUNE DEFENSE offers a biochemically diverse formula that provides optimum immune assistance.
How Do Mushrooms Work?
Mushrooms are a treasure trove of Bioactive compounds, but most of their immunomodulating activities have been attributed to polysaccharides (long-chain, simple sugars) and glycoproteins (polysaccharides naturally associated with proteins). These compounds activate a variety of immune responses.
MUSHROOM IMMUNE DEFENSE contains mycelia (networks of fibrous filaments) and extracts from the widest variety of mushroom species available. Included are the following mushrooms, which have demonstrated the most evidence for immune defense. Shiitake (Lentinula edodes): Lentinan, the beta glucan from shiitake, has been studied more extensively than similar substances and may be one of the most effective immunomodulators. Numerous studies have shown its ability to stimulate natural killer cell, T-cell, and macrophage-dependent responses.
Reishi (Ganoderma lucidum): Reishi’s polysaccharides may stimulate macrophages and enhance T-cell proliferation, according to in vitro studies.
Maitake (Grifola frondosa): Maitake enhances the activities of natural killer cells, T-cells and macrophages, according to animal studies. MUSHROOM IMMUNE DEFENSE contains MaitakeGold 404™, a highly specialized maitake product, rich in beta-glucans, which is the only maitake betaglucan fraction endorsed by the world’s premier maitake researcher, Dr. Hiroaki Nanba, Ph.D. Turkey Tails (Trametes versicolor): These mushrooms have a long history of traditional use in Asia. One in vitro study suggests that its polysaccharides stimulate macrophages.
Almond portabella (Agaricus blazei): This mushroom may stimulate the immune system by increasing T-cell activity, according to animal studies.
Cordyceps (Cordyceps sinensis): Cordyceps came to international attention during National Games in China when, in one week, three women’s track and field world records were broken. The coach partially credited a cordyceps elixir. Cordyceps was found to augment antibody and other immune responses in one animal study, and a cordyceps polysaccharide was found to elevate cytokines in vitro.
MUSHROOM IMMUNE DEFENSE contains 10 additional mushrooms, including enoke, oyster, Polyporus umbellatus, and Poria cocos. Vitamin C is added to enhance absorption and activity.
Unparalleled Immune Support
A focus on immune support can pay tremendous dividends for your entire life. If you are dedicated to good health, you want a powerful formula on your side. Source Naturals is proud to join forces with your natural foods retailer to bring you an unparalleled immune formula: MUSHROOM IMMUNE DEFENSE.
Heart Science - A Five-Tiered Approach to Heart Health ...
June 02, 2005 12:07 PM
Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.
Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health
Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
Energy Generators for An Energetic Organ
Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.
There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.
CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10
Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.
Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21
HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.
B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.
The Dangers of Oxidized LDL Cholesterol
While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.
When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.
The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.
Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.
Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:
The Regulating Trio
Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.
Artery Lining Protectors
Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6
Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.
The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.
Source Naturals HEART SCIENCE™
Diet Phen - Dietary Supplement and weight Loss ...
June 01, 2005 12:36 PM
Getting slim, trim and fit is no easy task. To do it you need adequate Energy, Nutritional and Emotional Support, and a Positive Attitude. Source Naturals puts them all together in the DIET-PHEN Weight Loss Plan. The plan includes an herbal-safe nutrient formula that combines optimal amounts of St. John’s wort with synephrine and green tea extract, plus L-phenylalanine and chromium. Meet your weight loss goals the natural way. Try Source Naturals DIET-PHEN dietary supplement in conjunction with the Diet-Phen Weight Loss Plan.
THE PLAN HELPS TO:
DIETING – It Starts in Your Head.
Successful dieting depends on the right mind-set: you need a positive outlook and determination. When your head is in the right place, your body may follow. That’s why the DIET-PHEN Weight Loss Plan includes natural herbs and amino acids to help support a sense of active calm.
ST. JOHN’S WORT – The CenterPeace of DIET-PHEN. In use since ancient times, Hypericum perforatum is a flowering herb highly valued for its positive influence on mental well-being. Known for its soothing effect, it seems to promote relaxation without drowsiness. Recent research has focused on the connection between hypericin (the principal phytochemical in St. John’s wort) and serotonin, a key neurotransmitter associated with mood. About 90% of your serotonin receptors are found in your brain’s emotional center, the limbic system.
SYNEPHRINE, GREEN TEA AND L-PHENYLALANINE – Energize with an Attitude! Synephrine and green tea extract are added for that extra energy needed during dieting. The brain uses phenylalanine to manufacture dopamine and norepinephrine, two neurotransmitters that play an important role in drive and determination.
ACETYL L-CARNITINE – Transporting Fat to the Furnace. Within each of your trillions of cells are thousands of tiny energy factories called mitochondria. They convert fats and sugars into metabolic energy. Acetyl L-carnitine supports this process by transporting fat molecules to the mitochondria.
THE PLAN INCLUDES A DAILY SERVING OF 3 DIET-PHEN TABLETS TO PROVIDE:
GET STARTED WITH THE PLAN ! Get DIET-PHEN dietary supplements and the Weight Loss Plan at VitaNet health food store.
Cholestrex - Lower Cholesterol with Source Naturals Supplements
June 01, 2005 10:41 AM
Our lives depend on an uninterrupted flow of blood throughout the 60,000 miles of arteries, veins, and capillaries that bring vital nourishment to our cells. Our bodies have complex chemical strategies to maintain and repair blood vessel walls. Cholesterol is an important part of the process. However, too much cholesterol in the bloodstream can have serious consequences for our well-being. By understanding how nutrition affects blood cholesterol, we can gain valuable control of our health. Source Naturals CHOLESTREX has been formulated to provide the nutritional support that we need to maintain healthy cholesterol levels.
SINCE DOCTORS FIRST DISCOVERED that cholesterol was the primary ingredient in the sticky deposits that clogged their patients’ arteries, scientists have gained a thorough understanding of cholesterol’s role in our health. Essential to human and animal life, cholesterol is part of every cell in the body. Because cholesterol is so important, the liver synthesizes from 1 to 2 grams of it each day. In addition, we get about another 500 mg from the foods we eat. Problems occur when too much cholesterol gets into the bloodstream. Today, it’s estimated that over 50 million adults in the United States have cholesterol levels that are too high. The body’s processes to manage excess cholesterol depend upon a lifestyle that includes exercise, stress reduction and proper nutrition. Source Naturals Cholestrex is designed to deliver a comprehensive combination of nutrients known to support a healthy blood vessel system – and keep the life stream flowing.
The nutrients in CHOLESTREX are known to support a healthy blood vessel system
Cholesterol: What It Is Cholesterol is a solid waxy substance, technically classed as a “sterol.” Cholesterol enables our cell membranes to maintain their integrity. It is the basic raw material from which the body makes steroid hormones, which include the sex hormones. Cholesterol is the primary component of bile salts that the liver creates to help us assimilate fats, fat-soluble vitamins and essential fatty acids. The liver also uses bile to rid itself of stored toxins. Our skin contains large amounts of cholesterol, making it resistant to the absorption of water-soluble toxins. Even the brain is 7% cholesterol (dry weight).
Blood vessel walls cover a surface area of half an acre and are under constant pressure
Cholesterol in the Blood
Because it’s not water-soluble, cholesterol must be attached to a carrier molecule in order to be transported in the bloodstream. The liver manufactures two types of carrier molecules for cholesterol, LDL and HDL. LDL (low density lipoprotein) molecules carry cholesterol from the liver out to cells of the body. One of its functions is to repair damaged cells, including those of the artery walls. LDL is primarily made up of saturated fats, (meat fats, butter, etc.). HDL (high density lipoprotein) molecules transport cholesterol and fatty acids from body tissues back to the liver for disposal. HDL helps remove excess fat and cholesterol from the bloodstream. HDL is composed of liquid fats (most vegetable oils). It’s crucial to have a proper balance between LDL and HDL cholesterol. High LDL – a sign that the body has too much fat – is a threat to the health of blood vessels, because excess LDL cholesterol may accumulate in damaged areas of vessel walls. These “fatty streaks” are the beginning stage of artery blockage.
The oxidation of LDL cholestrol is at the heart of the problem
Cholesterol and Artery Damage
The walls of the blood vessels cover a surface area of half an acre and are under constant pressure. Of all the blood vessels in the body, the coronary arteries are under the greatest stress. Named for the Latin word for crown (corona), they sit directly on the heart muscle and must continually expand and contract with every heartbeat. That’s 100,000 times each day. This constant squeezing can cause small lesions in the artery wall. This triggers a repair process where LDL cholesterol comes in to patch up the damage. Recent research has found that the crux of the problem is the oxidation of LDL cholesterol. Rich in fatty acids, the LDL molecule becomes permanently altered when oxidized by free radicals (overreactive molecules that steal electrons from other molecules). These rancid, oxidized LDL molecules are no longer recognized by the body, so they’re attacked by immune system cells. These immune cells become bloated with the oxidized lipids, accumulate in artery lesions and create plaque in blood vessels. Why is LDL cholesterol being oxidized? First of all, there’s too much of it in the blood, while not enough HDL. Secondly, the blood doesn’t have enough antioxidants to neutralize free radicals. The ingredients in Source Naturals Cholestrex address these specific problems in several ways. Cholestrex also provides nutrients that protect and strengthen blood vessel walls.
In the typical American diet, 95% of the cholesterol meant for removal is reabsorbed
Cholestrex Has It All
Vitamin C helps maintain the health of artery walls because it’s the key building block for collagen and elastin, the primary constituents of blood vessels. Copper is required by the enzyme that weaves together the fibers of collagen and elastin into the matrix that makes vessel walls both tough and flexible. As an antioxidant, vitamin C scavenges free radicals in the blood plasma and also regenerates vitamin E within the LDL molecule. Vitamin E has a critical role as the primary protector of LDL, preventing its oxidation. One molecule of vitamin E can protect 200 molecules of polyunsaturated fatty acids from free radical damage. GTF Chromium is involved in insulin activity and the normalization of blood sugar. Excess simple sugars are converted to triglycerides, the blood fats which can accumulate in artery walls. Lecithin is a component of HDL that emulsifies excess blood fat so it can be more readily transported in the bloodstream to the liver, where it’s metabolized. Vitamin B3 (niacin) assists in the metabolism of fats, and puts an electric charge on red blood cells so they repel each other, which prevents blood clumping. The amino acid, L-Arginine, works to lower serum cholesterol and triglycerides by inhibiting fat absorption.
Beta sitosterol neutralizes incoming dietary cholesterol
The Body’s Cholesterol Removal System
HDL molecules carry cholesterol from tissues throughout the body back to the liver, where it is incorporated into bile salts. These bile salts are sent to the intestines, where they combine with fiber for excretion. One problem with the typical American low fiber diet is that 95% of the bile-bound cholesterol is reabsorbed. Since this is the body’s primary pathway for ridding itself of excess cholesterol, another strategy incorporated into Cholestrex is to maximize the production of bile salts and minimize their reabsorption by increasing levels of fiber. Fiber is a key element of Cholestrex. Its four types of soluble fiber bind with bile salts that are laden with cholesterol to ensure their excretion from the body. Oat Bran & Fiber, Grapefruit Pectin, Psyllium Seed Husks and Alfalfa Seeds also absorb cholesterol from our food, thereby lowering total blood cholesterol. Alfalfa seeds are considered a blood purifier. Beta sitosterol, a plant equivalent of cholesterol, binds to sites in the intestines that would otherwise absorb cholesterol. Cholestrex provides a daily total of 300 mg of beta sitosterol which may, by itself, neutralize 200 to 300 mg of incoming dietary cholesterol by preventing its absorption. Vitamin C, among its many other vital roles, is the key factor in activating an enzyme that will increase the liver’s conversion of cholesterol into bile salts. CHOLESTREX uses Bioactive mineral ascorbate forms of vitamin C that will not irritate the digestive system. Working in conjunction with the fiber in CHOLESTREX, Calcium increases HDL, while lowering total serum cholesterol.
Cholestrex–Intelligent Nutritional Support
Our generation is fortunate to witness the remarkable progress made by modern science in understanding the body’s complex biochemical processes. As we realize the vital connection between nutrition and cholesterol levels, we are empowered to improve our health and vitality beyond previous standards of wellness. Source Naturals CHOLESTREX. For you and the ones you love.
Chem-Defense - Fight Chemical sensitivity ...
June 01, 2005 10:21 AM
CHEMICAL SENSITIVITY IS REAL.
COURTESY OF THE INDUSTRIAL REVOLUTION, OUR ENVIRONMENT HAS BECOME A STEW OF FOREIGN CHEMICALS. For some people suffering the malaise, lack of focus, and drained feeling associated with chemical sensitivities, home is the only sanctuary from this onslaught. For others, not even home is safe. We at Source Naturals take this threat very seriously. That’s why we created CHEM-DEFENSE.
Source Naturals’ CHEM-DEFENSE is a potent combination of Molybdenum, Glutathione, and Coenzymated B-2, nutrients which research has shown may help break down and dispel harmful chemicals from the body. And CHEM-DEFENSE is sublingual — it dissolves under the tongue so it goes directly into your bloodstream, where it can be delivered to your system, fast.
major problem has hit America in the late 20th century that is more far reaching than most people are aware — chemical sensitivity. In fact, some studies indicate that 1 out of 3 Americans may be afflicted with chemical sensitivities. In the past century, modern organic chemistry has synthesized and released into the world an estimated 300,000 xenobiotic (foreign to our normal biology) chemicals. The food processing and food growing industries put an approximate 10,000 xenobiotic chemicals into our food supply alone. These chemicals can be found in common items such as cleaning fluids, drycleaning compounds, glues, cigarette smoke, perfume, building materials and processed foods. Chemical sensitivity is the result of impairment or inadequacy of the body’s natural detoxification systems, allowing excessive levels of harmful, xenobiotic chemicals to accumulate in the body, and the results are often devastating. In sensitive people, artificial chemicals can cause an incredible range of problems: “fogginess” and lack of focus, emotional distress, fatigue, and more. The parts of the body that are most affected can vary from person to person. Some of the worst offenders are the aldehydes. The most infamous of these is formaldehyde (found in such widely used items as permanent press clothing, particle board, paints and upholsteries). The other common culprit is acetaldehyde (produced by Candida overgrowth or from alcohol consumption).
The Secret to CHEM-DEFENSE’S Power is Molybdenum
Fortunately, nature has provided the body with a special aldehyde detoxification pathway: an enzyme called aldehyde oxidase (ADO). ADO is activated by one of the coenzyme forms of Vitamin B2, Flavin Adenine Dinucleotide (FAD), and the trace mineral Molybdenum. Unfortunately, this enzymatic pathway can become impaired due to overexposure to foreign chemicals. In addition, aging, nutritional deficiencies, genetics and general poor health can greatly diminish the body’s production of these enzymes, causing a toxic buildup of aldehydes, leaving many individuals vulnerable. Current nutritional research has revealed that supplementing the diet with Molybdenum and Coenzyme B-2, both found in CHEM-DEFENSE, can increase levels of the important enzyme ADO, helping to dispel toxins from the body. A study published in the Townsend Letter for Doctors confirms the benefits of a sublingually administered 300 mcg dose (100 mcg three times a day) of Molybdenum. It was found that on the average, about 50-65% of the various symptoms of chemical sensitivity — including fogginess and other discomforts — were alleviated at least to some degree. Molybdenum is also important for several other enzymes, including xanthine oxidase, and most importantly, sulfite oxidase. Sulfite oxidase is responsible for breaking down sulfites, chemicals widely used as preservatives in wines, salad bars, produce, and other foods. Sulfites are a common culprit in chemical sensitivity reactions. In fact, by the 1980’s, it was conservatively estimated that 5,000,000 (five million) Americans were sensitive to sulfites and experienced discomfort upon ingestion. Sulfite oxidase is also important in the sulfation of various compounds, especially in the brain. This is particularly important, as the brain is often dramatically affected during bouts of chemical sensitivity. According to the Nutrition Desk Reference, the amount of Molybdenum required daily for people is 100 mcg to 500 mcg. It also states that the amount of Molybdenum in food can vary tremendously, depending on crop soil levels. Low levels are not at all uncommon, and they are lessened even further by commercial farming practices that utilize synthetic fertilizers which do not put Molybdenum back into the soil. The result? The typical American diet does not provide adequate Molybdenum. The form of Molybdenum included in CHEM-DEFENSE is Molybdenum Aspartate-Citrate, Molybdenum bound to the cellular metabolites Aspartic Acid and Citric Acid. This has been shown to be the most Bioactive form available by experts in mineral metabolism.
Glutathione in its Most Bioavailable Form
Ultimately, the one organ that must cope with and attempt to relieve the body of toxic chemicals is the liver, often referred to by nutritionists as “the body’s most overburdened organ.” To accomplish this, the liver must rely heavily on Glutathione, a tripeptide (three amino acids bound together). The Glutathione in CHEM-DEFENSE will help the liver to produce adequate levels of the important enzymes glutathione peroxidase (GSHpx) and glutathione S-transferase (GSH-S), enzymes that are essential for breaking down and disposing of foreign chemicals in the body. Glutathione peroxidase (GSHpx) helps to break down hydrogen peroxide, a medium-level toxin which is found in many xenobiotic chemicals. GSHpx also prevents cell damage caused by fatty acid oxidation, which threatens the integrity of cell membranes. Glutathione is very fragile. In fact, when taken orally, it is often destroyed by protein-digesting enzymes in the stomach. As CHEM-DEFENSE is in sublingual form, it bypasses the digestive process and goes straight into the bloodstream, allowing for maximum activity.
Coenzyme B2 — The “Recycling” Nutrient
Once Glutathione is used in the body for its detoxification functions, it becomes oxidized Glutathione, meaning it has been “used up.” Fortunately, the human body can “recycle” oxidized Glutathione and return it to its beneficial reduced (active) state. This process is made possible by a coenzyme form of Vitamin B2 (FAD), which is present in CHEM-DEFENSE.
Sublingual Delivery for Maximum Benefit
Many nutrients, when taken orally, are never completely absorbed into the bloodstream, or not absorbed at all! Because this formula is in sublingual form, the nutrients in CHEM-DEFENSE are absorbed directly into the bloodstream through the blood vessels under the tongue and in the cheeks, assuring maximum bioavailability and benefit. In America today, as foreign chemicals continue to be released into the environment on an uncontrolled basis, people continue to experience chemical sensitivities for which there appears to be no solution. Now there is. Source Naturals CHEM-DEFENSE combines the most bioavailable forms of key antioxidant nutrients that are not only powerful in and of themselves, but work together synergistically to address the problems associated with chemical sensitivities. As with all of their other products, Source Naturals has taken special care to create a product that is all natural, hypo-allergenic, and sugarfree. CHEM-DEFENSE sublingual is available in two delicious flavors — natural peppermint, and for people on homeopathic regimens who prefer an alternative to peppermint, natural orange flavor. Let’s face it — life in the modern world is a battle for your health. Arm yourself with a powerful weapon: Source Naturals CHEM-DEFENSE.