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  Messages 1-73 from 73 matching the search criteria.
What Cellular Mitochondria Does in the Body Darrell Miller 4/28/22
Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ... Darrell Miller 4/22/19
High levels of CoQ10 can lower your chances of dementia by 77% Darrell Miller 2/8/19
Give your healthy diet a boost with supplements - USA TODAY Darrell Miller 8/27/17
CoQ10 — A Nutritional Powerhouse for Mitochondrial Health Darrell Miller 12/27/16
What Are The Benefits Of Ubiquinol Vs Regular CoQ10? Darrell Miller 5/31/14
How Coenzyme Q10 or CoQ10 cure Cardiovascular? Darrell Miller 5/30/14
Boost Energy With CoQ10 And L-Carnitine Darrell Miller 11/21/13
What Is Ubiquinol? Darrell Miller 8/23/13
CoQ10: What You Ought to Know about This Substance? Darrell Miller 3/26/13
What Causes High Blood Pressure And What Can Reduce And Prevent It? Darrell Miller 12/28/12
What Makes Ubiquinol The Best Form Of COQ10? Darrell Miller 3/8/12
Free Radicals And Cancer, How Do I Combat Free Radicals? Darrell Miller 10/12/11
How Does Coenzyme Q10 Improve Energy Levels and Our Health? Darrell Miller 10/4/11
stroke, what is it? Darrell Miller 9/28/10
Natural Vitamins for the Heart Darrell Miller 7/6/10
Natural Remedies To Control Blood Sugar Darrell Miller 6/17/10
Antioxidants and your health Darrell Miller 5/17/10
Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it Darrell Miller 2/25/10
Herbs, Serrapeptase, and your Sinus Darrell Miller 2/18/10
Thrombophlebitis Darrell Miller 4/15/09
Vitamins and Herbs Darrell Miller 4/3/09
Phytoestrogen Darrell Miller 3/27/09
Boost Memory Darrell Miller 3/23/09
Psyllium Husk Fiber Darrell Miller 3/18/09
Migraines Darrell Miller 2/21/09
Hay Fever Darrell Miller 2/19/09
What is Alpha Lipoic Acid? Darrell Miller 7/18/08
Supports Healthy Blood Pressure Darrell Miller 4/18/08
Health And Applications Of Coenzyme Q10 Darrell Miller 4/17/08
Ubiquinol Darrell Miller 4/16/08
Ubiquinol Reduced CoQ10 Darrell Miller 4/7/08
Alpha Lipoic Acid is a Powerful Antioxidant Darrell Miller 2/15/08
Seniors Need More Than a Multiple with Only 100 Percent of the RDA Darrell Miller 1/21/08
Give Your Health A Boost With Silica Hydride A Powerful Antioxidant Darrell Miller 1/18/08
Your Mouth Has A Lot To Say About Your Health Darrell Miller 1/10/08
Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver Darrell Miller 12/18/07
Support Healthy Joint Function With Discount Vitamins Darrell Miller 11/22/07
Ubiquinol Darrell Miller 10/24/07
Natural Coenzyme Q10 (Ubiquinone) Darrell Miller 7/27/07
Active Coenzyme Q10 Darrell Miller 7/7/07
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium Darrell Miller 5/18/07
CoQ10 for Heart Health Darrell Miller 3/28/07
Neurological Health and CoQ10 Darrell Miller 2/25/07
Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more. Darrell Miller 11/9/06
Lower Cholesterol Naturally! Darrell Miller 10/6/06
HDL Booster - Boost your good cholesterol Darrell Miller 3/16/06
High Absorption CoQ10 Darrell Miller 2/13/06
The Free Radical Theory Darrell Miller 12/14/05
Coenzyme Q10 and Cardiovascular Health. Darrell Miller 12/13/05
Put a spring in your step with these energizing tips Darrell Miller 8/2/05
Natural Health for a Healthy Heart Darrell Miller 7/13/05
New* Improved formula - Cholest-Response Lower Cholesterol Darrell Miller 7/8/05
NEW PRODUCT ANNOUNCEMENT Darrell Miller 7/5/05
Life Force - The Energy Activator Darrell Miller 6/29/05
SPECIFIC ACTIONS ASSOCIATED WITH GARLIC Darrell Miller 6/25/05
RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available Darrell Miller 6/24/05
REFERENCES Darrell Miller 6/22/05
CLA and Ather osclerosis Darrell Miller 6/22/05
Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement Darrell Miller 6/21/05
Pep Up and Go! Darrell Miller 6/14/05
Acupuncture nutrient Connection Darrell Miller 6/12/05
Maximum Absorption Darrell Miller 6/10/05
Cross Training Darrell Miller 6/10/05
Menopause Multiple - Eternal Woman Darrell Miller 6/3/05
NutraSpray in Melatonin, Proanthodyn, and St. John's wort Darrell Miller 6/3/05
Higher Mind - Smart Nutrients for the Performance of a Lifetime... Darrell Miller 6/2/05
Heart Science - A Five-Tiered Approach to Heart Health ... Darrell Miller 6/2/05
HEART RESPONSE - Comprehensive Support for a Healthy Heart! Darrell Miller 6/2/05
Fibro Response - Feel your Vitality ... Darrell Miller 6/2/05
Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement Darrell Miller 6/1/05
COENZYME Q10 - Transforming food into energy Darrell Miller 6/1/05
Re: Its in the Blood Darrell Miller 5/9/05



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What Cellular Mitochondria Does in the Body
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Date: April 28, 2022 04:19 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What Cellular Mitochondria Does in the Body

If you want to stay healthy, it's important that you know what cellular mitochondria does in the body. Mitochondria are organelles found in the cytoplasm of cells. They are responsible for producing energy for the cell. Without them, the cell would not be able to function properly. We will discuss the role of mitochondria in the body, and how they impact our health.

What are mitochondria and what do they do in the body

Mitochondria are organelles that play an important role in the energy metabolism of cells. Most of the oxygen we breathe is used by mitochondria to convert glucose from the food we eat into ATP, the energy molecule used by our cells. Therefore, mitochondria are often referred to as the "powerhouses" of the cell. In addition to producing ATP, mitochondria also have other important functions, such as regulating cell growth and death, as well as calcium homeostasis. Mitochondria are unique in that they have their own DNA separate from the DNA in the cell nucleus. This mitochondrial DNA is passed down from mother to child, which is why defects in mitochondrial function can lead to diseases that are inherited in a maternal lineage. Although most of our cells contain only a single nucleus, they may contain hundreds or even thousands of mitochondria. This allows them to produce enough ATP to meet the energy needs of the cell.

How mitochondrial dysfunction can lead to health problems

Mitochondria are integral to many essential physiological processes in the body. Not only do they produce energy for cells, but they also play a key role in maintaining cellular structures and initiating cell division. Therefore, any disruption of normal mitochondrial function can have far-reaching consequences for overall health and well-being. Maladaptive responses to environmental stressors, such as chemical exposure or radiation, are among the most common causes of mitochondrial dysfunction. These stressors result in damage to mitochondrial DNA and can cause problems with cell division and abnormal growth patterns, which can lead to a range of disorders and chronic diseases. For example, mitochondrial dysfunction has been linked to conditions like Alzheimer's disease and type 2 diabetes, as well as cardiovascular disease and cancer. Therefore, it is important to understand the role that mitochondria play in maintaining healthy functioning bodies and take proactive steps to prevent or reverse damage from maladaptive responses to environmental stressors.

Mitochondria and Longevity

Mitochondria are specialized organelles found within our cells that perform many critical functions, including generating energy to support cellular processes and maintaining healthy cell function. These organelles are the site of many important chemical reactions, often referred to as oxidative phosphorylation or metabolism. Studies have shown that Proper functioning of these organelles is essential for healthy aging, and may be a key factor in determining how long we live. By promoting mitochondria health and making lifestyle changes that help to promote healthy mitochondria, we can take an important step towards optimizing our longevity potential. This includes eating a nutrient-rich diet with a focus on foods high in antioxidants, managing stress levels through regular exercise and relaxation techniques, and avoiding environmental toxins that can damage mitochondria health. Through such strategies, we can give ourselves the best chance at living a long, full life.

Ways to protect your mitochondria and keep them healthy with PQQ

PQQ, or pyrroloquinoline quinone, is an important molecule for the functioning of mitochondria in the human body. This compound plays a crucial role in adenosine triphosphate (ATP) synthesis, the fundamental energy currency of biological systems. By driving cellular processes that release energy for metabolic use, PQQ plays a key role in maintaining mitochondrial health and efficiency. Additionally, PQQ has been shown to exhibit powerful antioxidant properties, which help to mitigate the effects of oxidative stress on mitochondria and other critical cells in the body. Overall, PQQ is an essential component of healthy mitochondrial function and a crucial nutrient for energy production and overall metabolic health.

D-ribose, the Mitochondria, and Energy

D-ribose is a naturally occurring sugar that plays an important role in cellular metabolism and energy production. This nutrient is especially important for cells that rely on a lot of energy, such as those found in the heart and muscles. D-ribose helps these cells to generate adenosine triphosphate, or ATP, which is the main energy currency used by cells to drive chemical reactions. Additionally, research has suggested that d-ribose can help to improve physical endurance and reduce the pain and stiffness associated with exercise, making it an important part of a healthy, active lifestyle.

Also, D-ribose is a simple sugar that plays an important role in the structure and function of mitochondria, the powerhouses of the cell. In addition to supplying energy to the cells, mitochondria also help to regulate cell growth and death. D-ribose is essential for the proper function of mitochondria, and it plays a key role in energy production. Studies have shown that D-ribose can help to improve mitochondrial function and reduce fatigue. In addition, D-ribose supplements have been shown to improve exercise performance and increase energy levels. These effects are likely due to the ability of D-ribose to help the body produce more ATP, the energy currency of the cell. For these reasons, D-ribose is an important nutrient for maintaining healthy mitochondria and supporting cellular energy production.

Another important nutrient for the mitochondria is CoQ10

The process of producing energy is called oxidative phosphorylation, and it involves the transfer of electrons from nutrients to oxygen. This reaction creates a proton gradient across the mitochondrial membrane, which is used to generate ATP, the energy currency of the cell. Coenzyme Q10 (CoQ10) is an important component of this process. It acts as an electron carrier, shuttling electrons between enzymes in the respiratory chain. It also helps to maintain the proton gradient, allowing the mitochondria to continue generating ATP. Without CoQ10, oxidative phosphorylation would grind to a halt, and cells would quickly run out of energy. Consequently, CoQ10 plays a vital role in energy production and cellular metabolism.

The bottom line is that both D-ribose and CoQ10 are important nutrients the body needs to maintain optimal energy levels. If you’re feeling run down, low on energy, or just generally not your best, consider taking a supplement containing these two nutrients. You may be surprised at how much better you feel once you start including them in your diet. What’s stopping you from giving them a try?

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Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ...
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Date: April 22, 2019 04:29 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ...





Many Coenzyme Q10 products have labels that indicate that their product is better absorbed due to longtime beliefs surrounding ubiquinol (reduced Coenzyme Q10) being hard for the body to absorb. Many brands instead market ubiquinone, which is redox Coenzyme Q10 instead, since studies have been more supportive about this form being easier for the body to absorb. New research, however, is concluding that both of these forms are equal when it comes to the ability to be absorbed through the body.

Key Takeaways:

  • According to Coenzyme Q10 expert Dr. William Judy, there is very little difference in the absorption rates of ubiquinol and ubiquinone.
  • Both forms of CoQ10 contain antioxidants and are critical for overall mitochondrial health.
  • CoQ10 can be beneficial for those suffering from Parkinson's disease and has been shown to provide headache relief in adolescent and pediatric populations.

"Marketing terms such as “better absorbed” should be questioned unless the absorption or bioavailability is actually stated. Only when the actual absorption has been verified can the better absorbed product be determined."

Read more: https://wholefoodsmagazine.com/columns/vitamin-connection/coenzyme-q10-research-confirms-ubiquinone-and-ubiquinol-are-nearly-equally-absorbed-compounds-the-physical-form-and-companion-ingredients-make-the-bioavailability-and-absorption-difference-in-coenz/

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High levels of CoQ10 can lower your chances of dementia by 77%
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Date: February 08, 2019 08:30 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: High levels of CoQ10 can lower your chances of dementia by 77%





There is now even more reason to ensure that you're taking a CoQ10 supplment. New evidence suggests that it can lower your risks of developing dementia by 77% or more! This is in addition to the many amazing health benefits this substance is already known to offer. If you want to live the best life being the healthiest you that you can live, it is worth adding CoQ10 supplement to your diet sooner instead of later!

Key Takeaways:

  • The fight against dementia is ongoing. Foods like berries are known to reduce risk to it but more exciting is the discovery that Coenzyme Q10 can reduce your risk.
  • The study involved measuring the serum CoQ10 levels of older persons aged between 40 and 69. They measured these levels for those who had dementia and those who didn’t.
  • Their discovery was that people with high levels of CoQ10 were safer from dementia. The top 25 percent has a 77 percent lower chance of having dementia.

"Dementia, despite its prevalence, remains largely a mystery to doctors and scientists, who have yet to find a foolproof way to prevent or treat the illness."

Read more: https://www.naturalnews.com/2018-12-22-high-levels-of-coq10-can-lower-your-chances-of-dementia.html

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Give your healthy diet a boost with supplements - USA TODAY
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Date: August 27, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Give your healthy diet a boost with supplements - USA TODAY





There are many supplements out there. You have to research them so you can get good ones because they aren't all created equal, but there are reasons why taking them is helpful. They help you get the nutrients you need in case your diet is lacking. They can also help you if you are low on something because of a health condition. A good balance of nutrients will help your body to perform at its very best.

Key Takeaways:

  • Older women's bodies do not absorb nutrients as efficiently as they age.
  • Some supplements including calcium vitamin D, Magnesium, Omega 3 Fatty acids, Vitamin B-12, Resveratrol, turmeric, grapeseed oil, coenzyme Q10, and general multivitamins may benefit older women.
  • It is advisable to check with one's doctor before beginning a new supplement.

"It seems as if there isn’t anything that Curcuma longa can’t do."

Read more: https://www.usatoday.com/story/news/nation/2017/08/18/give-your-healthy-diet-boost-supplements/579373001/

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CoQ10 — A Nutritional Powerhouse for Mitochondrial Health
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Date: December 27, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CoQ10 — A Nutritional Powerhouse for Mitochondrial Health





Coenzyme Q10, which is referred to as CoQ10 is gaining popularity in the supplement marketplace. The number of Americans who are using this supplement has risen to twenty-four million people. This is good news as research shows its benefits. New research shows it keeps the mitochondria healthy, allowing for oxygen to be converted to energy.

Key Takeaways:

  • At present, at least 1 in 4 American adults over the age of 40 are taking a statin — ostensibly to protect their heart health.
  • This is the enzyme inhibited by statin drugs. This means that, in addition to lowering your cholesterol, the drug also compromises your body's ability to benefit from a healthy and cleaner-burning fuel (fat).
  • Recent research found that taking CoQ10 in combination with selenium improves heart function and cuts cardiovascular mortality by nearly 50 percent in elderly people.

"Between 2000 and 2016, the number of Americans using CoQ10 increased from an estimated 2 million to 24 million, and the number of brands featuring CoQ10 has increased from 18 brands to 125."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.prohealth.com/library/showarticle.cfm%3Flibid%3D29771&ct=ga&cd=CAIyGjVkYjY3ZDViNDdiNGM3ZTc6Y29tOmVuOlVT&usg=AFQjCNFStHXdUv1oYIMpcXavYYI0sc130w

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What Are The Benefits Of Ubiquinol Vs Regular CoQ10?
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Date: May 31, 2014 06:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Benefits Of Ubiquinol Vs Regular CoQ10?

fruits and vegetables Nutritional Supplement

In modern society, nutritional supplements have become a common method to improve health. A wide range of specific needs determines the use of different supplements, but there are a few that will work in just about everyone and improve their health.

What is a CoQ10

Coenzyme Q10, commonly abbreviated to CoQ10, is one of those universally effective supplements. This vitamin-like substance offers far-reaching benefits for the human body. It has a crucial role in the body's energy maintenance and it's an extremely powerful antioxidant. This substance is naturally produced by the body, but as we get older, the organism's ability to synthesize CoQ10 weakens progressively. It is, therefore, recommended that people initiate a regular intake of CoQ10 somewhere at the adult or even young adult life stage. This is a commonly prescribed supplement for old people owing to its longevity and energy inducing benefits, but it's especially critical for those who are medicated with statin drugs because these are known to reduce CoQ10 levels in the organism. Elite athletes can also benefit from this substance to achieve higher peak power levels.

CoQ10 supplement is available in two forms: fully oxidized (Ubiquinone) and fully reduced (Ubiquinol).

What is an Ubiquinol

Ubiquinol is the most efficient way to take advantage of this supplement because it's the fully reduced form of CoQ10 that our body actually absorbs and uses. The consumption of Ubiquinone requires our body to firstly metabolize and convert it into Ubiquinol. This process limits the speed and efficiency of CoQ10 absorption, requiring larger quantities to be consumed for similar health effects, not to mention that the metabolism has a tendency to worsen with age. Ubiquinone is more widely available and is cheaper, though.

It is usually recommended for people around the age of 35 - 40, to start taking Ubiquinol instead of Ubiquinone. This is when the efficiency of Ubiquinol eventually compensates its higher price tag over Ubiquinone. Turning the ingestion of CoQ10 supplement into a habit is one of the best ways to potentiate a long and healthy life.

Sources:

  1. en.wikipedia.org/wiki/Ubiquinol
  2. en.wikipedia.org/wiki/Coenzyme_Q10#Biosynthesis
  3. articles.mercola.com/sites/articles/archive/2013/11/03/coq10-vs-ubiquinol.aspx
  4. www.bodybuilding.com/fun/coq10-ubiquinone-ubiquinol-whats-the-difference.htm
  5. www.ncbi.nlm.nih.gov/pmc/articles/PMC3661336/

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How Coenzyme Q10 or CoQ10 cure Cardiovascular?
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Date: May 30, 2014 08:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Coenzyme Q10 or CoQ10 cure Cardiovascular?

CoQ10What is a CoQ10

Coenzyme Q10 is shortly known as CoQ10. Coenzyme Q10 is a type of antioxidant, which is made in the human body. Actually, Coenzyme Q10 or CoQ10 is such an element like a vitamin. This component was first found in 1957. Undoubtedly, it performs a vital role to generate necessary energy in cells. It also helps the human body from damaging of cells.

Benefits of CoQ10

CoQ10 is great stuff as a dietary supplementary. It also helps a lot to treat the Cardiovascular Disease. Undoubtedly, it is a perfect remedy for the heart diseases. It is such a component, which enhances the athletic abilities. It also contributes to slow aging.

According to a survey, CoQ10 reduces the systolic pressure about 11 to 18 points and meanwhile 8 to 10 points for the diastolic pressure. The people whose have critical heart disease; they possess a lower amount of Coenzyme Q10. The cells of the heart are very sensitive, but Coenzyme Q10 can handle the heart diseases comfortably. Another survey showed us that, the death rates of those, whose are affected by heart disease and have a low amount of Coenzyme Q10 is increased. Actually, Coenzyme Q10 benefits the total cardiovascular system for the health. Its antioxidant helps a lot to benefit the cardiovascular system. Actually, these are not enough to recommend CoQ10 for cardiovascular. It has already performed a great performance on the cardiovascular system. A recent review has showed us that CoQ10 gradually reduces the death rates among the heart disease's patient. However, it has some negative impact on Diabetes, Hepatitis C but it is the top most dependable component of the heart disease or improving cardiovascular to be honest. Therefore, it proves that it is side effect free for your heart and no doubt you can count on it.

 

Sources

  1. //www.berkeleywellness. com/ supplements/ other-supplements/article/can-you-count-coenzyme-q10
  2. //en.wikipedia. org/wiki/ Cardiovascular_disease
  3. //www.mayoclinic. org/ drugs-supplements/coenzyme-q10/background/ hrb-20059019
  4. //www.webmd. com/ heart-disease/heart-failure/tc/ coenzyme-q10-topic-overview

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Boost Energy With CoQ10 And L-Carnitine
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Date: November 21, 2013 08:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Energy With CoQ10 And L-Carnitine

CoQ10 and L-Carnatine

 L-CarnatineCoQ10 and L-Carnitine offer double protection for the heart and the brain in just a single tablet. You obtain all benefits for your heart at 100% from CoQ10, while L-Carnitine supports your memory, learning ability, and focus. The exclusive combination of CoenzymeQ10 and L-Carnitine encloses an absorbable, water soluble capsule of CoQ10 and L-Carnitine, which is important for proper usage.

Why are CoQ10 and L-Carnitine Supportive in Energy Boost?

CoQ10 Energy Boost

CoQ10 is a vital nutritional element found in all body cells, in particular the mitochondria, in which most energy is generated. The major function of this coenzyme is to assist in the process of oxygen and food conversion into energy. As people grow older their ability to naturally, to produce this coenzyme decays.

At the same time as Coenzyme Q10 is taking part in the production of energy in each cell of your body, it is considered be remarkably imperative for the high energy requirements of the heart. The heart needs vast energy amounts, because it is the hardest worker in your entire body. Coenzyme Q10 seems to be indispensable for this process. It offers you sufficient antioxidant provision, protecting the body cells from damage of the free radicals, and proffering a dynamic function of the immune system.

L-Carnitine Energy Boost

L-Carnitine transports indispensable fat acids into the same organ where CoQ10 plays its major function - the mitochondria. There, with the help of L-Carnitine, all fatty acids are turned into energy. However, the beneficial function of L-Carnitine does not end here. In addition, it also supports the transportation of toxins outside the body. You can think of the problems that might occur if these vital body processes are not fully operational. At the same time however, the major impact of L-Carnitine over the body is directed towards the brain:
  • Cognitive function and concentration support
  • Cell membrane health support
  • Improves clarity and happiness
Encouraging the overall health of your brain, while offering your heart supreme support, the combination of CoQ10 and L-Carnitine is the best solution for you, in terms of:
  • Supporting your heart's energy needs
  • Providing essential nutrition for all cells of the body
  • Delivering powerful antioxidants, which protect your body
References:
  1. //www.webmd.com/heart-disease/heart-failure/tc/coenzyme-q10-topic-overview
  2. //www.webmd.com/vitamins-supplements/ingredientmono-1026-L-CARNITINE.aspx?activeIngredientId=1026&activeIngredientName=L-CARNITINE
  3. //www.poliquingroup.com/ArticlesMultimedia/Articles/Article/767/Top_12_Reasons_to_Use_Carnitine.aspx
  4. //nutritionalengineering.org/coq10-acetyl-l-carnitine-supplement.htm
  5. //www.livestrong.com/article/489829-why-should-i-take-l-carnitine-with-coq10/

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What Is Ubiquinol?
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Date: August 23, 2013 02:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Ubiquinol?

Coenzyme Q10 (Co10) is a naturally-occurring chemical compound in the body which fuels cell growth and enhances enzyme functions. It exists in three forms; ubiquinone (fully oxidized), semiquinone (partially reduced), and ubiquinol (fully reduced). So, ubiquinol is basically a reduced form of Co10, it is a strong antioxidant that can neutralize free radicals. Free radicals refer to a reactive and unstable atom that can trigger many medical conditions such as cardiovascular issues, weak immunity and even cancer.

Ubiquinol is found in almost every organ, tissue and cell in mammals. This lipid-soluble benzoquinol can be acquired through supplementation, biosynthesis and from diet (in small amounts). Ubiquinol plays an integral role in transferring electrons within the body, thereby leading to ATP synthesis. The antioxidant property of ubiquinol is very essential in the functioning of the cellular systems.

Ubiquinone is naturally converted into ubiquinol by the body to produce energy for the cells. The failure of this process can lead to insufficient energy levels in the body. The ability of the body to generate Coenzyme Q10 reduces with age and so does the ability to convert ubiquinone into ubiquinol. Therefore, older people should use ubiquinol supplements to boost their energy levels. Apart from older people, those who suffer from neurological, cardiovascular, diabetes and liver conditions may also have low ubiquinol levels.

There are many health benefits associated with ubiquinol. First, it offers a sufficient amount of energy which the heart needs to work well. It's also a strong antioxidant that protects the heart, and other vital body organs from free radicals. When it comes to energy, ubiquinol is an essential component in 95 percent of the energy produced in the body. Daily intake of ubiquinol supplement can help reduce fatigue and muscle pains; the common symptoms of insufficient Coenzyme Q10 in the body. Since ubiquinol is a strong fat soluble antioxidant, it can protect the body from oxidation, thereby providing an anti-aging benefit.

Do you feel fatigued, run down with no energy?  Consider Ubiquinol as a natural safe energy boosting supplement.

References

  1. //en.wikipedia.org/wiki/Ubiquinol
  2. //products.mercola.com/coq10-ubiquinol/
  3. //www.kanekaqh.com/benefits-of-ubiquinol.html

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CoQ10: What You Ought to Know about This Substance?
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Date: March 26, 2013 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10: What You Ought to Know about This Substance?

Coenzyme Q10 or simply CoQ10 is a substance naturally present not only in a human's body but as well as with the other mammals. It plays a vital role in the production of energy. Back in the year 1957, Dr. Frederick Crane successfully used the mitochondria from the cells of a beef heart in order to locate Coenzyme Q10. But the truth of the matter is that, the substance is also present in human mitochondria. Basically, this substance has antioxidant properties which are highly beneficial in protecting the body against the free radicals present in the environment. Below are some relevant details you ought to know about this substance.

Here they are:

CoQ10 in Kreb's Cycle

There are a number of chemicals that the body needs to induce metabolism and one of those chemicals is CoQ10. The Kerb's Cycle is the body's mechanism to convert certain enzymes into energy. In order to achieve that, the body needs CoQ10 to facilitate the conversion of the enzymes in energy production. CoQ10 is fundamental in the Kerb's Cycle as it supports the electron transport chain in which the oxidative phosphorylation of the ADP (adenosine diphosphate) into ATP (andenosine triphosphate) needs electrons that are exactly delivered where they must be. Without CoQ10, the entire Kerb's Cycle process would certainly fail. The mitochondria of every power cells synthesize CoQ10 so the substance is present in almost all the body parts. However, the heart consumes the most CoQ10 for the reason that it has the most number of mitochondria and it keeps on working even while the body is at rest.

CoQ10 Deficiency

If the Kerb's Cycle fails due to CoQ10 deficiency, the person will feel exhausted and weak. But aside from that, there are other conditions that are often associated with the deficiency such as cardiovascular related diseases, Parkinson's disease and gum disease. Conversely, it doesn't necessarily mean that those diseases are brought about by CoQ10 deficiency.

CoQ10 Dietary Sources

The main sources of CoQ10 include fish oil, whole grains and organ meats. With a balance diet, people can get sufficient amount of Coenzyme Q10.

CoQ10 Supplements

Aging is an inevitable process and it can affect the synthesis of CoQ10. As humans grow older, the production of the Coenzyme Q10 gradually decreases. It was mentioned earlier some of the foods that are incredibly beneficial in maintaining ample amount of CoQ10 in the body. But people who do not really include those foods in their diet should not worry for there are now food supplements that contain CoQ10.  Some medications like cholesterol meds can prevent the body from using CoQ10, this is when it is essential for one to take a supplement.

Fortunately, with the advent of medical researches and innovative technology in drug manufacturing, CoQ10 can now be ingested into one single tablet, soft gel capsule, hard shell capsule or an oral spray. CoQ10 is a fat-soluble substance so taking it along with foods is highly encouraged.

Who Takes CoQ10 Supplement?

Children under 18 years old are not allowed to take CoQ10 supplements unless prescribed by the doctor. For adults at the age of 19 or older, the recommended dosage in 30 - 600 mg daily. Higher dosage may be taken for special conditions.

Humans need energy in order to carry out all the tasks. Therefore, CoQ10 must be taken daily, whether from foods or supplements, so the body has the energy to move.

Have you had your CoQ10 Today?

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What Causes High Blood Pressure And What Can Reduce And Prevent It?
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Date: December 28, 2012 11:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Causes High Blood Pressure And What Can Reduce And Prevent It?

High blood pressure is one of the most common conditions people suffer from in first-world countries; throughout the last few decades civilized countries have becomes exponentially more reliant on technology, without forgetting the rise of the fast food industry. In conjunction with the sedentary lifestyles most people lead nowadays, this has led to an increase of people with cardiovascular health problems. According to the American Heart Association, around 33% of adults in the United States are suffering from hypertension.

The silent killer

The disease is not known as the silent killer for nothing, as a person can live with it for years and years without even experiencing any symptoms. However, as time goes by the disease starts to take its toll on the body, with symptoms including dizziness, headaches and nosebleeds. However, if gone unchecked for a long time the condition is going to worsen considerably, eventually leading to the development of serious cardiovascular problems, including coronary heart disease.

What precisely causes high blood pressure?

For starters, one's body fat percentage plays an important role; the more fat a person has, the more the walls of their arteries are clogged, the higher the blood pressure rises. A lack of physical activity has also been known to help the condition develop as it forces your heart to contract itself more often. Intake of products such as tobacco, alcohol, sodium and potassium can all lead to an increase in your blood pressure, as well as your risk of heart disease.

Stress is a factor which often gets overlooked, but the truth is that when you tense up, your heart starts pumping blood faster, which consequently increases the pressure in your arteries. Finally, there is the one factor which cannot be controlled: genetics. Indeed, if a person has a family history of hypertension, that person is likely to suffer from it as well.

While it is possible to treat high blood pressure with chemical over-the-counter pharmaceutical remedies, they often bring about a slew of side effects which can cause problems even worse than the ones experienced with the blood pressure.

Natural Remedies

Fortunately, there are a few natural remedies which can be used to fight the condition.

For starters, you can take magnesium supplements which are sold by numerous companies, generally in the form of capsules. Magnesium is the most common mineral needed by the body and it helps to regulate one's blood levels. If you don't feel like taking supplements, you could always eat foods rich in magnesium, which basically translates to consuming lots of green vegetables, nuts, seeds and unrefined grains. 

Hibiscus tea

Hibiscus tea is another apparent miracle of nature; drinking it on a regular basis will slowly decrease one's hypertension. A clinical study was actually conducted in order to determine the tea's effectiveness, and it was found that it can noticeably improve the condition of those suffering from mild or moderate hypertension.

Coenzyme Q10

Finally, you might want to look into the Coenzyme Q10, a natural supplement which has undergone clinical studies. More precisely, there was a twelve-week double-blind placebo-controlled study involving eighty-three subjects with hypertension. They were treated for the entire duration with 17.8 mm Hg of the Coenzyme Q10, and in the end their pressure was significantly reduced.

Needless to say, there are countless more natural remedies which can help deal with high blood pressure, with the best part being that most of them don't cost much and are readily available for purchase anywhere. In some cases, you can even do it at home by yourself. All in all, as long as there are natural methods to try it is highly recommended that you stay away from pharmaceutical treatments; not only will they burn a hole in your wallet, they may very well leave you worse for wear.

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What Makes Ubiquinol The Best Form Of COQ10?
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Date: March 08, 2012 11:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Ubiquinol The Best Form Of COQ10?

Benefits of Ubiquinol

Ubiquinol is an active antioxidant form of CoQ10. It is pre-converted and ready-to-use diet supplement. Hence, it is easily absorbed and utilized by the body. Research studies show that ubiquinol has proved to be much more effective than ubiquinone and has all vital health benefits as CoQ10.

Ubiquinol is the next generation supplement which provides support for a healthy body and mind. It helps you to live a healthy life by raising your CoQ10 plasma level. It also plays an important role in production of energy levels. Moreover, it protects the cells of the body from oxidative kind of stress which can eventually damage proteins, DNA, and lipids.

Benefits of Ubiquinol:

Cardiovascular health: Clinical studies show that ubiquinol improves the overall cardiovascular health. Cardiac patients who have been taking high dosages of statins like Lipitor, Zocor, etc for a long period of time have decreased levels of Coenzyme Q10 as these statins inhibit the body's production level of Coenzyme Q10. The low levels of CoQ10 in the body can result in cardiomyalgia, fibromyalgia, atherosclerosis, etc. Thus, if these patients take ubiquinol which is an antioxidant then it neutralizes the oxidation of LDL.

Cognitive Health: It helps to increase the stamina and energy and promotes general health and wellness.

Anti-aging support: Due to degeneration and advanced age, the aged people have less CoQ10 biosynthesis and body's conversion ability also diminishes in such subjects. A collaborated study carried out on middle aged people demonstrated that subjects who were given this supplement showed marked improvement in their physical and mental activities. Thus ubiquinol by and large promotes life extension and improves the overall mental health by compensating for the age-related conversion disability.

Power to other organs: Ubiquinol plays an important role in igniting energy levels within the cells of vital organs like heart, kidneys, liver, and lungs. Thus it naturally helps you to sustain your energy levels.

Protects Cells: Ubiquinol protect cells of vital organ like heart from further damage and from constant attack by free radicals.

Neuronal Health: Ubiquinol benefits the neurological system and promotes brain health. Studies carried out on patients who had Parkinson's disease have proved that it reduces the functional decline in these patients.

Oral Health: Ubiquinol impacts the oral health and significantly enhances the salivary Coenzyme Q10 levels. It affects all aspects of mouth, teeth, lips, tongue, and salivary glands.

Renal Health: Studies show that Ubiquinol gives significant renal protection to patients who have chronic kidney disease.

Your body constantly produces powerful antioxidants daily when you are young. But as you age, your body can not sustain this natural production level forever. Hence ubiquinol supplementation is important to promote overall good health. Ubiquinol can be used as a dietary supplement. Its ready-to-use formula is eight times more effective as it can be readily absorbed by your body. Thus it is an ideal diet supplementation for current CoQ10 users.

At present there are no known side effects of ubiquinol, but if you are on multi-drug therapy or are already taking other supplementations, then please consult your doctor prior taking this diet supplementation Ubiquinol.

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Free Radicals And Cancer, How Do I Combat Free Radicals?
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Date: October 12, 2011 01:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Free Radicals And Cancer, How Do I Combat Free Radicals?

Free Radicals Overview

Free radicals, just the very sound of those words are so dreaded in so many consultation clinics around the country today, this substance has mainly been linked to cancer and its proliferation but what else is there to know about free radicals and cancer. This is what we will be looking at as we go along this article. These free radicals are organic molecules which are primarily the cause for aging, damaged tissues, and a variety of diseases. The main property that causes them to bind with other molecules in the body there by causing damage is because it is unstable. This is the non-stop process that these molecules will do, destroy cells, takes away its vigor and initiate this pro aging process. In a way it is the natural order of things, our world is filled with so many unstable molecules and just like us, there survival instincts kick in and they have to keep stable. Outside the body, that’s all good, no harm for us, but when the same process occurs inside that’s where our own survival instincts come in and helps us think of ways to stop this process of degeneration. With this degeneration process of cells being damaged, it is not far fetch to see these free radicals as the cause of some disease most especially Cancer.

Cancer

Cancer has been a close second as the top killing disease in America for the past few years now, 2011 is not over yet so there is no ranking out but my guess is, the top 2 will most likely be the same with number one still being heart disease. Cancer is basically characterized by out of control cell growth. There are many classifications of cancer and one thing remains constant, it is characterized or named based on what type of cells it began to damage to cause the eventual cancer. For many of us out there what we do not want to here are malignant tumors in the body and this can occur based on 2 things, when cancerous cells spreads around the body through the bloodstream which is often referred to as an invasion process and the second is when the cancerous cells divide and grow leaving tissues metastasized in a process called mestastasis. Tumors grow and uncontrollably which are lumps of masses that interfere with our normal bodily functions and causes systems to crash like our digestive and nervous systems just to name a few.

The Answer:Antioxidant

Antioxidants has been well known to be one of the best ways to fight cancer, present in many foods, these molecules does its handy work against cancer by going to the source. More research needs to be done in its healing effects but as an effective treatment it has been proven to be an integral part in minimizing further proliferation of damaged cells. Antioxidants have been shown to have an amazing characteristic against free radicals and that it plays an integral role in killing these cell damaging molecules in the body.

List of antioxidants:

This by far a complete list, but it will get you get started with an antioxidant program to help prevent disease caused by free radical damage.

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How Does Coenzyme Q10 Improve Energy Levels and Our Health?
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Date: October 04, 2011 04:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Coenzyme Q10 Improve Energy Levels and Our Health?

One of the most amazing and essential chemical cofactors is Coenzyme Q10. This specific cofactor plays a crucial role for the body because it is required by cells to produce enough energy to sustain life. Studies revealed that Coenzyme Q10 can increase the level of energy of all the muscles in the body therefore, it is beneficial most especially for the cardiac muscles to achieve optimal rate.

Coenzyme Q10 also provides the immune system with enough power and energy so that the body will be protected from injurious pathogens. It can also help in releasing fat storage by enhancing oxygen utilization. Because of the fact that the production of Coenzyme Q10 decreases as we age, there is a great need to take supplements so that we will not be depriving our body with the health benefits that it offers. Below is the array of health benefits that Coenzyme Q10 is capable of offering:

Coenzyme Q10 toughens your protection against pathogens

It is an inevitable fact that our immune system requires enough energy to sustain it from performing its functions. Coenzyme Q10 has been proven essential in terms of strengthening the immune system especially in instances when an invader is detected. Coenzyme Q10 offers vital support to our natural killer cells (our first line of defense) in fighting bacterial and viral agents that could cause great harm to our body.

Another health benefit of Coenzyme Q10 is its capability in lowering the concentration and regulating the production of chemicals such as NF-kappaB, which could weaken our immune system. Based on the studies that were conducted, it has been unleashed that increasing blood levels of Coenzyme Q10 could enhance the antibody response to as much as 57% hence, it is highly essential in keeping our body well protected.

Coenzyme Q10 is good for you heart

We are aware that ATP is the primary unit of energy that is being utilized by the mitochondria of our cells; to sustain the process, the body only recognizes Coenzyme Q10 to act as chemical facilitator. A deficiency in the amount of Coenzyme Q10 in the body would also equate to poor muscle functioning.

As a matter of fact there was this study that revealed that when Coenzyme Q10 is combined with other forms of potent antioxidants like selenium, vitamin C and vitamin E, it can relevantly enhance the health of your heart and can lower down your risk of developing cardiovascular diseases.

Coenzyme Q10 can help you lose weight

This special coenzyme supplies your body with enough energy to ensure the efficacy of your exercise program by increasing fat metabolism and energy utilization. Because Coenzyme Q10 can help the conversion of energy components into a more useful form, it can help stimulate your metabolic rate thus helping you achieve the body that you have always wanted. Experts suggest that you should combine Coenzyme Q10 with regular aerobic exercise to make it more efficient for your body to get rid of fats.

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stroke, what is it?
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Date: September 28, 2010 03:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: stroke, what is it?

A stroke occurs when a clot forms inside an artery that blocks the flow of blood to the brain. This is also called a thrombus. Embolism, which is a wandering clot, is carried in the bloodstream until it wedges in one of the arteries that lead to the brain. Aneurysms are blood-filled pouches that balloon out from weak spots in the artery wall and burst. A hemorrhage results when a defective artery in the brain that bursts, flooding the surrounding tissue with blood.

A mild attack can lead to temporary confusion and light-headedness, along with difficulty in speaking clearly, weakness on one side of the body, visual dimness and confusion, severe speech difficulties, and/or sudden or gradual loss or blurring of consciousness. Additionally, amnesia can occur, but it is not typically permanent. A coma can even result for short or long periods.

It is important to watch for early warnings of stroke. Although they may only last a few moments, early warnings include fainting, stumbling, numbness or paralysis of the fingers of one hand, blurring of vision, seeing bright lights, and loss of speech or memory. It is much wiser and significantly less expensive to start improving health in order to prevent this disease. Some doctors who have treated thousands of people suffering from stroke believe that most strokes can typically be prevented.

The Chinese often view strokes as being caused by blood stasis and stagnation of the liver. Chinese medical practitioners attempt to prevent strokes and treat them by treating constipation. Constipation causes a poisoned bloodstream, setting the stage for a possible stroke. Poisoned blood flows through thousands of miles of arteries, veins, and capillaries. The walls of the arteries are made up for cells, which are subject to the same injury from toxins as the cells in the kidneys. The kidneys degenerate at the same time that the arteries do and even from the same causes. When the walls thicken and harden, degeneration results. As they harden they become more brittle, causing them to burst more easily under pressure. Pressure increases as the hole through the arteries grows smaller. AS the walls become more brittle, the extra pressure causes the blood pressure to rupture. This, in turn, causes a stroke. The brain cells rely primarily on oxygen-rich blood in order to get nourishment. If they don’t receive this nourishment, the brain cells will die. Other causes of this are poor diet, lack of exercise, obesity, and smoking.

Emotional health is an essential part to any healing. Strokes are often associated with resistance to change, giving up on life, and getting tired of doing all the same things over and over. It is important that we learn to accept changes and are able to go with the flow of life. Life can be exciting. Changes provide us with a new perspective on living.

Some herbs and supplements have been used to help as a preventative. These include vitamin E, vitamin C, Coenzyme Q10, garlic, evening primrose oil, lecithin, chlorophyll, flaxseed oil, and germanium. For additional information on any of these, please contact a representative from your local health food store.

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Natural Vitamins for the Heart
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Date: July 06, 2010 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins for the Heart

It has been consistently revealed by epidemiological research that individuals with a high dietary intake of antioxidant vitamins have a risk that is lower-than-average of cardiovascular disease. This evidence seems to be especially consistent for vitamin E. Additionally, many clinical studies show that magnesium supplementation is of significant benefit in the treatment of cardiac arrhythmias and in reversing the depletion of potassium that comes along with a magnesium deficit. Many cardiovascular events like angina pectoris, congestive heart failure, and cardiomyopathy are related directly to low magnesium status. Coenzyme Q10 is an essential component in cellular energy production. This nutrient is also prevalent in the heart muscle. When tissue levels of CoQ10 are low, there is an association with several cardiovascular complications. Among these are angina, congestive heart failure, cardiomyopathy, hypertension, and mitral valve prolapse. Research has found that the trio of Coenzyme Q10, vitamin E, and magnesium plays a crucial role in the maintenance of cardiac health and the prevention of disease states.

The cardio-protective effect of vitamin E seems to come from its ability to bind to LDL cholesterol, which protects it from free-radical induce oxidative damage along with the consequent buildup of atherogenic plaque. Low levels of vitamin E in the blood are a predictive factor of heart health almost 70% of the time.

Studies on the general population have suggested that there is a link between the intake of calcium and blood pressure. Although results of the studies have not been consistent, there are several studies showing that calcium supplementation can lower blood pressure in those individuals who experience hypertension. Overall, those intakes of calcium that are sub-optimal contribute directly to hypertension. It seems that dietary calcium reduces blood pressure by normalizing intracellular calcium levels.

Supplementation with magnesium is of benefit for the treatment of cardiac arrhythmias and the prevention of potassium depletion. Both magnesium and potassium play an important role in the functioning of the heart. Several studies have found that there is improvement in heart function in those patients that have cardiomyopathies when they supplement with magnesium. Since magnesium acts in so many ways to enhance cardiac function and optimize cellular metabolism, magnesium is widely recognized as a critical nutrient for general cardiac support.

Several double-blind studies have taken place in those patients that experience various cardiomyopathies in order to show the benefits of CoQ10 supplementation. One study reported an 89% improvement rate in 80 cardiomyopathy patients who were treated with CoQ10. The coenzyme also appears to moderate blood pressure through the usual mechanism, as it lowers cholesterol levels and also stabilizes the vascular system with its antioxidant properties. Because of this, it is able to reduce vascular resistance. Several studies on CoQ10 supplementation have confirmed that this nutrient posses the ability lower both systolic and diastolic pressures by up to ten percent.

There are other nutrients that play important roles in optimizing cardiovascular health and reducing hypertension. Among these nutrients are gamma tocopherol, calcium, magnesium, l-carnitine, acetyl-l-carnitine, procyanidolic oligomers, phenolic compounds, and lycopene. As you can see there are many natural supplements that can help the cardiovascular system. Remember to always consult your doctor before adding supplements to your diet while on prescription drugs. Look to your local or internet health food store for quality vitamins, herbs, and specialty formulas to boost your health and wellness.

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Natural Remedies To Control Blood Sugar
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Date: June 17, 2010 01:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Remedies To Control Blood Sugar

Diabetes has now been found to be the seventh leading cause of death in the United States and Canada. It is a chronic disorder of carbohydrate, fat, and protein metabolism. The disease starts off as a variety of metabolic changes that are associated with hyperinsulinemenia and hyperglycemia. When this happens, Insulin Resistance Syndrome results, which is a precursor to actual, full-blown, diabetes. If left untreated, insulin resistance will develop into full-blown diabetes, which includes greatly magnified risks of heart disease, stroke, eye and kidney disease, and loss of nerve function. It should be noted that diabetes is the principal cause of adult blindness and limb amputation.

Type 2 diabetes is the most common form of diabetes. In this type of diabetes, the body either does not produce enough insulin or the cells ignore the insulin. Insulin is crucial for the body to be able to use glucose for energy. The body breaks down all of the sugars and starches that you consume into glucose, while insulin takes the glucose from the blood into the cells. When glucose builds up in the blood instead of going into the cells, the cells may be starved for energy immediately, and high blood sugar glucose levels over time can cause damage to your eyes, kidneys, nerves, and heart. Diabetes occurs in people of all ages and races, with some groups having a higher risk for developing it than others. Diabetes is more common in African Americans, Latinos, Native Americans, and Asian Americans, as well as the older aged population.

Non-insulin-dependent diabetes, also known as type 2 diabetes, is a disease that is strongly associated with a sedentary lifestyle and the modern western diet. Inadequate physical activity, along with a diet that is high in refined sugars, saturated fats, and proteins, and simultaneously low in dietary fiber has resulted in an obesity epidemic throughout the United States and Canada. With this epidemic has risen the prevalence of type 2 diabetes. In fact, obesity is a main factor in type 2 diabetes, with almost 90% of those diagnosed with type 2 diabetes being obese at the time of diagnosis. Although there is still a disagreement as to whether obesity actually causes type 2 diabetes or whether diabetes causes obesity, there is one thing that is clear: the disease involves a huge disturbance to the metabolic balance of the body and weight is a major factor in blood sugar management. This disturbance leads to dramatic consequences for the individual.

In order to reduce the risk of type 2 diabetes, it is crucial that one prevents the onset of insulin resistance. Unfortunately, millions of North Americans unknowingly suffer from this syndrome. This places them at an increased risk for cardiovascular and neurological dysfunctions. Research has shown that complications that are associated with the development of insulin resistance may be mitigated effectively by conscientious dietary and lifestyle changes along with weight loss.

Vitamins B3, B6, B12, C, E, biotin, Coenzyme Q10, and the trace elements chromium, magnesium, manganese, and zinc are all crucial for proper blood sugar defense and metabolic support, as well as the regulation of glucose metabolism. Supplementation with these nutrients at levels that are determined to be suitable for optimal nutritional health by cited nutritional authorities is an important part of product-rating criteria. Nutritional experts ask themselves whether the product in question contains vitamin B3, vitamin B6, vitamin B12, vitamin C, vitamin E, biotin, Coenzyme Q10, chromium, magnesium, manganese, and zinc at potencies that are up to 100% of the potencies for these nutrients in the Blended Standard.

Excess weight seems to be a key factor in type 2 diabetes so it seems to reason that reducing body fat can help one improve insulin sensitivity. Losing weight is no easy task but is possible with consistent work. Fortunately, heath food stores have vitamin formulas that may help improve insulin sensitivity, but this is no substitute for good clean eating and exercise. For additional information on these supplements, please contact your local health food retailer.

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Antioxidants and your health
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Date: May 17, 2010 10:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants and your health

There is an impressive amount of scientific evidence supporting the health benefits of supplementing with a wide variety of antioxidants. Consequently, there are many health practitioners who have begun to recommend high dietary intakes of these crucial nutrients in order to prevent against oxidative stress. It was anticipated over two decades ago by leading researchers that high-dose supplementation with antioxidants is developing a significant role in the prevention and treatment of a lot of today’s common illnesses. It should be noted that antioxidants do not work in isolation. When an antioxidant neutralizes a free radical, it, itself, is oxidized and must be regenerated by another antioxidant before it can be used again. Because of this, it is crucial to supplement with a wide variety of antioxidants, in order to reflect what actually occurs in nature.

Vitamin C, an aqueous-phase antioxidant, is the main guard against oxidative attack in the extra-cellular matrix, as well as within the cytoplasm of the cell. Vitamin C happens to be a substrate for eight different enzyme systems that are involved in various cellular functions. Among these functions are collagen synthesis, ATP synthesis in the mitochondria, and hormone biosynthesis. Its main antioxidant partners are vitamin E and beta carotene, both of which help to regenerate vitamin C.

Of all the antioxidants, it seems as if vitamin E offers the greatest protection against heart disease because of its ability to protect the cardiovascular system from oxidative damage. It is lipid-soluble, making it an important component of the cell membrane, where it works to protect the cell against lipid peroxidation and control oxidation-induced inflammatory events. Recently, the gamma tocopherol form of vitamin E has shown a great deal of promise in its ability to reduce the risk of several oxidative stress related disease.

Beta-carotene is a member of a diverse group of photosynthetic pigments. It plays a huge role in human nutrition. As an antioxidant, it possesses a double-bond structure that allows it to react effectively with single oxygen radicals, absorbing and diffusing their energy. Beta-carotene also acts as a precursor for vitamin A by supplying a portion of the body’s requirement for the vitamin. This act alone plays a central role in the chemistry of vision. Beta-carotene and vitamin A both prevent the oxidation of cholesterol, reduce oxidative damage to DNA, and disable oxygen free radicals that are produced by exposure to sunlight and air pollution. These antioxidants are also involved in the activation of gene expression and the control of cell differentiation.

When combined together, vitamin C, vitamin E, and beta-carotene produce and important antioxidant trio that plays a huge role in fighting oxidative and inflammatory events. There are several other antioxidants that should be noted due to their ability to work synergistically with the vitamin C, vitamin E, and beta-carotene trio. These include vitamin A, alpha-lipoic acid, lycopene, Coenzyme Q10, and the antioxidant mineral, selenium. In order to determine whether a nutrient provides antioxidant support, scientists question whether the product contains vitamin C, vitamin E, vitamin A, beta-carotene, alpha-lipoic acid, lycopene, Coenzyme Q10, and selenium and to what strength these vitamins and minerals are per serving.

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it
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Date: February 25, 2010 09:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it

Aloe Vera Sunblock SPF30 LILY OF THE DESERTSunburn is the result of excessive exposure to the sun’s ultraviolet (UV) rays. The amount of exposure that is required to cause a burn is unique to each individual, the geographical location, the time, and the atmospheric conditions. There are two types of ultraviolet rays, which are designated as ultraviolet-A (UVA) and ultraviolet-B (UVB). Both types of ultraviolet rays are dangerous. UVB rays attack the skin’s outer layers, while UVA rays attack the underlying layers of the skin.

The majority of sunburns are first-degree burns that cause the skin to become red, warm, and tender to the touch. Depending on the severity of the burn and the individual’s skin type, the burn may subsequently “cool” into a suntan or thin layers of skin may peel off. More serious sunburn can be categorized as a second-degree burn. A second-degree burn consists of extreme reddening, swelling, pain, and even blisters. This is a sign that the burn has gone deeper than just the surface layer of the skin and has caused damage and the release of fluids from cells in the lower layers of the skin. The result of this is eruptions and breaks in the skin where bacteria and other infectious organisms can enter. In the most severe cases, a burn can be accompanied by chills, fever, nausea, and/or delirium. These types of sunburns are extremely painful and are extremely dangerous for children. Sunburn can often be accompanied by dehydration.

Those people who are fair-skinned are more prone to sunburn than those darker-skinned individuals. However, no matter what your skin color, you will burn if you get enough exposure. Symptoms do not always appear while you are in the sun, as they may begin from one hour to twenty-four hours after sun exposure and they usually reach their peak in two to three days. Natural Mineral Oil Free Sunblock SPF18 4 fl oz from ALBA BOTANICA

The effects of sun exposure are becoming an increasing concern today due to the decline in the earth’s ozone layer. The ozone layer is responsible for screening out the most harmful ultraviolet rays, but it is becoming increasingly thinner all over the world. Holes that fluctuate in size have even developed in various places. Additionally, the incidence of skin cancer is growing at an alarming rate. It has been found that having two or more bad episodes of sunburn as a child can make you much more likely to develop skin cancer as an adult.

The following nutrients are recommended for prevention and treatment of sunburn: Coenzyme Q10, colloidal silver, DMB, a free-form amino acid complex, L-cysteine, a multivitamin and mineral complex, potassium, Pycnogenol, vitamin A with mixed carotenoids, vitamin C with bioflavonoids, an all-purpose bactericide spray, calcium, magnesium, essential fatty acids, silica, a vitamin B complex, vitamin E oil, and zinc.

Additionally, the following herbs may be beneficial in treating sunburn. Aloe vera gel has been noted to be remarkably effective in treating any kind of burn. It is responsible for relieving discomfort, speeding healing, and also helping to moisturize the skin and relieve dryness. A salve of calendula flowers and St. John’s wort can act as painkiller for burns and promote healing of skin wounds because these herbs have antiseptic properties.

Also, Lavender oil or chamomile oil used in a herbal bath can help to minimize the stinging and pain of sunburn. Comfrey and gotu kola tea can be made it to a compress for the affected area. Horsetail is good for tissue repair, while tea tree oil can help to heal sunburn and other skin irritation. Apple cider vinegar diluted with water is a great wash for sunburned areas.

To prevent sunburns, apply sunblock on any exposed skin before going out side to prevent skin damage before it starts.

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Herbs, Serrapeptase, and your Sinus
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Date: February 18, 2010 04:26 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs, Serrapeptase, and your Sinus

sinus CavitiesSinusitis occurs when the nasal sinuses become inflamed. There are sinuses that are located above the eyes (frontal sinuses), inside the cheekbones (maxillary sinuses), behind the bridge of the nose (sphenoid sinuses), and in the upper nose (ethmoid sinuses). Sinuses are air-filled pockets in the skull that are connected to the nose and throat by passages designed to drain away mucous. The sinuses are the first line of defense to protect the lungs from infection. The majority of sinusitis cases affect the frontal and/or maxillary sinuses. However, any or all of the sinuses may be involved, with each individual tending to have problems with a particular set of sinuses. If the sinuses are too small or happen to be poorly position to handle the volume of mucous produced, they can become clogged. This causes pressure in the sinuses to increase, which causes pain. Those sinuses that are clogged for a long time are extremely prone to infection.

Sinusitis can be either acute or chronic. Acute sinusitis is usually caused by bacterial or viral infections of the nose, throat, and upper respiratory tract, like the common cold. Over 50 percent of all cases of sinusitis are caused by bacteria. Air travel can also lead to acute inflammation of the sinuses, due to the changes in air pressure. Chronic sinusitis problems, on the other hand, may be caused by small growths in the nose, injury of the nasal bones, air pollution, dental complications, emotional stress, smoking, and exposure to irritant fumes and smells. Allergic sinusitis may be the result of hay fever of food allergies, especially those allergies to milk and dairy products. People who have compromised immune systems are susceptible to fungal sinusitis, which is a potentially dangerous condition that requires aggressive treatment.

Sinusitis is characterized by symptoms such as fever which is usually low-grade but can be higher in some cases, cough, headache, earache, toothache, facial pain, cranial pressure, difficulty breathing through the nose, loss of the sense of smell, and tenderness over the forehead and cheekbones. If pain results from tapping the forehead just over the eyes, the cheekbones, or the area around the bridge of the nose, the sinuses may be infected. Sinusitis occasionally produces facial swelling which can be followed by a stuffy nose and a thick discharge of mucous. Those who suffer from sinusitis can have other unpleasant symptoms as a result of previous symptoms. Postnasal drip can cause a sore throat, nausea, and bad breath, while difficulty breathing can cause snoring and loss of sleep.Serrapeptase from Solaray

The following nutrients are considered to be helpful in dealing with and preventing sinusitis: acidophilus, bee pollen, flaxseed oil, a multivitamin and mineral complex, Quercetin, raw thymus glandular, vitamin A with mixed carotenoids, vitamin B complex, vitamin C with bioflavonoids, vitamin E, Coenzyme Q10, colloidal silver, DMSO, garlic, MSM, proteolytic enzymes, Pycnogenol, sea mussel, serrapeptase, and zinc lozenges.

Additionally, the following herbs may be helpful in preventing and treating sinusitis: anise, fenugreek, marshmallow, red clover, bayberry, bitter orange oil, cat’s claw, ginger root, goldenseal, horehound, mullein, nettle, olive leaf extract, and rose hips. Serrapeptase is an enzyme that is able to help keep sinus fluid thin and flowing properly. Serrapeptase also possesses anti-inflammatory properties and can help reduce sinus inflammation which will ease pain and speed healing of the sinus cavity.

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Thrombophlebitis
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Date: April 15, 2009 01:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Thrombophlebitis

Thrombophlebitis is when inflammation occurs in the veins due to the formation of a blood clot in that vein. This problem usually occurs in the extremities, especially the legs. Thrombophlebitis can be considered superficial if it affects the subsutaneous vein, which is one of the veins near the skin’s surface.

In superficial thrombophlebitis, the affected vein can be felt and may be seen as a reddish line under the skin. Additionally, swelling, pain, and tenderness to touch can occur. If widespread vein involvement is included, the lymphatic vessels may become inflamed. Superficial thrombophlebitis is a relatively common disorder that can be brought about by trauma infection, standing for long periods of time, lack of exercise, and intravenous drug use. The risk of superficial thrombophlebitis can be increased by pregnancy, varicose veins, obesity, and smoking. Thrombophlebitis can also be associated with environmental sensitivities to allergies. This condition is usually diagnosed according to physical findings and a medical history that indicates an increased risk.

Deep thrombophlebitis (DVT) affects the intramuscular veins farther below the skin’s surface. DVT is a much more serious condition than superficial thrombophlebitis because the veins affected are larger and located deep within the musculature of the leg. These veins are responsible for the transport of 90 percent of the blood that flows back to the heart from the legs. Symptoms of DVT may include pain, warmth, swelling, and bluish discoloration of the skin of the affected limb. These symptoms are often accompanied by fever and chills. The pain is typically felt as a deep soreness that is worse when standing or walking and gets better with rest, especially with elevation of the leg. The veins directly under the skin may become dilated and more visible. Inflammation situated in a vein in the pelvis is referred to as pelvic vein thrombophlebitis.

The reason or reasons for the formation of the clots in the veins are often unknown. However, in most cases, clots are probably the result of a minor injury to the inside lining of a blood vessel. If the vessel lining receives a microscopic tear, clotting is initiated. Platelets clump together to protect the injured area, and a series of biochemical events is initiated that results in the transformation of fibrinogen, a circulating blood protein, into strands of insoluble fibrin, which are deposited to form a net that traps blood cells, plasma, and yet more platelets. This results in a blood clot. Other possible causes of the formation of DVT include abnormal clotting tendencies; poor circulation; certain types of cancer; and Behcet’s syndrome, which is a condition that affects small blood vessels that predispose an individual to the formation of clots. The following factors increase the risk of DVT: recent childbirth, surgery, trauma, the use of birth control pills; and prolonged bed rest.

The following nutrients are recommended for the prevention and treatment of thrombophlebitis: acetyl-l-carnitine, Coenzyme Q10, flaxseed oil, garlic, l-cysteine, lecithin granules, l-histidine, magnesium, MSM, Pycnogenol, vitamin C with bioflavonoids, vitamin E, zinc, and vitamin B complex. Additionally, the following herbs may be beneficial: alfalfa, pau d’arco, red raspberry, rosemary, yarrow, butcher’s broom, cayenne, ginger, plantain, witch hazel, skullcap, valerian root, ginkgo biloba, goldenseal, hawthorn, and olive leaf extract.

Natural vitamins are a great way to help prevent conditions such as these. If you suspect that you have thrombophlebitis, consult your doctor before trying to take the problem into your own hands. Natural vitamins such as the ones listed above can be found at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Vitamins and Herbs
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Date: April 03, 2009 02:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamins and Herbs

The whole human body is made up of cells that contain their own genetic material. In a healthy body, these cells divide at a controlled rate, growing and repairing damaged tissues and replacing dying cells. This predetermined rate of cell division is what keeps our bodies healthy. If cells keep multiplying when new ones are not necessary, a mass of tissue, often known as a tumor, is formed. This tumor can be either benign or malignant.

Benign tumors are not cancerous and can occur anywhere in the body. Benign tumors do not cause a threat to health, do not metastasize, and do not grow back if removed. Malignant tumors are cancerous and are usually serious. Often times, they can be life-threatening. Malignant tumors grow uncontrollably, interfere with normal metabolic and organ functioning, and have the ability to metastasize and invade other tissues. If a portion of a cell’s DNA is damaged, the cell can become abnormal. When an abnormal cell divides, it forms new cells that are a photocopy of the damaged genetic material. This ongoing process occurs constantly within our bodies. The majority of the time our bodies have the ability to destroy these abnormal cells and maintain a sort of cellular equilibrium. If a crucial part of the DNA is destroyed and the abnormal cells cannot be controlled any longer, cancer forms. All cancer cells have two things in common: growing uncontrollably and having the ability to metastasize. The immune system does not recognize cancer cells as dangerous or foreign.

Although the exact cause for the cell damage that initiates the cancer process is unknown (theoretically free radical damage causes DNA damage), the chain of events that leads to cancer is very complex, and each individual body reacts differently. It is a combination of genetic, behavioral, environmental, and lifestyle factors that are thought to be involved in turning normal cells into abnormal cells, and abnormal cells into cancer.

There are also factors that are believed to slow the process, while other factors can speed up the process. Possible contributors to the development and growth of cancer can be divided into three categories: external, internal, and lifestyle. External factors include unhealthy workplace environments and exposure to air and water pollution, chemicals, pesticides, and herbicides. Included in the internal factors include both genetics and infections. Lifestyle factors are those we personally can most readily control, such as diet, smoking, drinking, and sun exposure. External and lifestyle factors account for 80 percent of cancer deaths in the United States.

Just as each of us looks different, each of our bodies has its own unique composition. Some of us may react adversely to what some of us react well to. This is why some treatments prove to be successful for some, but not for others. This is why dietary wellness and prevention is so important. If we can keep our bodies healthy and avoid known cancer-causing agents, we have a good defense against cancer in the first place.

The following nutrients and supplements are designed for persons who have been diagnosed with cancer, as well as for those who wish to enhance their chances of avoiding the disease: Coenzyme Q10, colostrum, DMG, garlic, IP6, melatonin, MSM, proteolytic enzymes, selenium, 7-keto DHEA, shark cartilage, SOD, vitamin A, shiitake extract, acidophilus, chromium picolinate, flaxseed oil, grape seed extract, kelp, l-carnitine, multienzyme complex, a multi-mineral complex, multivitamin complex, NAC, raw glandular complex, taurine, and vitamin B complex. Additionally, the following herbs may be beneficial: astragalus, birch, burdock root, cat’s claw, chaparral, chuchuhuasi, cranberry, dandelion, Echinacea, fennel, green tea, licorice root, macela, milk thistle, parsley, pau d’arco, red clover, suma, cardamom, cayenne, ginger, rosemary, sage, thyme, turmeric, ragwort, wood sage, curcumin, essiac, noni, olive leaf extract, rosemary, and boswellia.

All of the above listed herbs and vitamins can help restore the body to good nutrition and help boost the immune system so the body can find and fight back against cancer. Natural vitamins and herbs are available at your local or internet health food store. When purchasing supplements, look for name brand vitamins like Solaray and Source Naturals to ensure you receive quality and you get what you pay for.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.



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Phytoestrogen
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Date: March 27, 2009 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Phytoestrogen

Menopause is the time at which a woman stops ovulating and menstruation ceases, which indicates the end of fertility. Menopause is not a disease, but rather a natural progression in life, similar to puberty. Many years before a woman stops ovulating, her ovaries will begin to slow their production of the hormones estrogen, progesterone, and testosterone. Estrogen and progesterone are often thought of as the reproductive hormones.

Although estrogen is essential in reproduction, it is also extremely important in other non-reproductive organs and systems in the body. Cells in the uterus, bladder, breasts, skin, bones, arteries, heart, liver, and brain all contain estrogen receptors. These organs need this hormone in order to stimulate these receptors for normal cell function. Estrogen is needed to keep the skin smooth and moist and the body’s internal thermostat working properly. Estrogen is also essential for proper bone formation. Even though estrogen levels drop sharply after menopause, they do not disappear entirely. Other organs take over for the ovaries, continuing to produce a less potent form of estrogen. These organs, known as endocrine glands, secrete some hormones from fatty tissue in order to maintain bodily functions.

Progesterone works along with estrogen, stimulating changes in the lining of the uterus to complete the preparation for a fertilized egg during the second half of the menstrual cycle. If no egg is fertilized, the uterine lining is broken down and expelled, allowing the cycle to being again. Progesterone also has effects beyond the reproductive system, as it calms the brain and also affects other aspects of nervous system function. Testosterone is most important for both men and women, with women producing about 80 percent less than men do. However, it is the driving force for maintaining a healthy life and proper functioning organs.

The period when a woman’s body is preparing for menopause is known as perimenopause. For the majority of women, hormone production beings to slow down then they reach their thirties, continuing to diminish with age. Many women will experience few if any symptoms at this time, but others may suffer from anxiety, dry skin, fatigue, feelings of bloating, headaches, heart palpitations, hot flashes, insomnia, irritability, decreased interest in their significant other, loss of concentration, mood swings, night sweats, reduced stamina, urinary incontinence, uterine dryness and itching, weight gain, cold hands and feet, joint pain, hair loss, and/or skin changes.

Menopause occurs when a woman stops menstruating altogether. At this point, most of the acute problems a woman may have experienced are actually over and a new balance between all hormones should be established. However, women become increasingly vulnerable to other, potentially serious health problems at this time. Over the long term, the diminished supply of estrogen increased the likelihood of cardiovascular disease, osteoporosis, and uterine atrophy. Osteoporosis especially is a major problem for women after menopause, with an estimated 80 percent of the hip fractures that occur in the United States every year being due to osteoporosis.

A proper diet, nutritional supplements, and exercise can help to minimize or eliminate most of the unpleasant side effects of menopause. The following nutrients are recommended for dealing with this stage of life: beta-1, cerasomal, Coenzyme Q10, DHEA, essential fatty acids, lecithin granules, a multi-enzyme complex, soy protein, vitamin B complex, vitamin D3, vitamin E, boron, calcium, magnesium, quercetin, silica, zinc, l-arginine, multiglandular complex, a multivitamin and mineral complex, vitamin C, aloe vera gel, slippery elm, damiana, amaranth, chickweed, dandelion greens, nettle, seaweed, watercress, anise, black cohosh, fennel, licorice, raspberry, sage, unicorn root, wild yam root, hops, valerian root, gotu kola, red clover, dong quai, St. John’s wort, and Siberian ginseng.

All these above listed vitamins and herbs are available in capsule, tablet, or powder forms. When looking for natural alternatives to help replace estrogen naturally, look to your local or internet health food store for name brand products that can help restore an imbalance over time.

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Boost Memory
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Date: March 23, 2009 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Memory

Our memory is as natural to us as breathing. An ability we all have, but don’t often think of, it doesn’t seem to cross our mind until we perceive that we are losing the ability. Memory lapses are an annoyance in themselves, but the anxiety that often comes along with them seems to be even worse. We often wonder if our memory problems are a symptom of some other problem like midlife depression, arteriosclerosis, or even Alzheimer’s disease. Although Alzheimer’s disease is a fairly common disorder among older people, one must realize that most memory lapses have nothing to do with Alzheimer’s disease.

Generally, it is believed that increasing age brings about an increased likelihood of developing memory loss. The mildest form of this illness is called age-associated memory impairment. This is characterized by one’s perception of his or her own memory loss and it is estimated that it is experienced by 40 percent of Americans over the age of sixty-five. Not all memory loss is attributable to aging, as occasional memory lapses are a natural normal part of life at almost any age, and are not likely to precede serious memory loss. With a proper diet, nutrition, and memory use, the memory should remain sharp and active well into one’s nineties or beyond.

One big reason why people suffer from memory loss is an insufficient supply of necessary nutrients to the brain. The life of the body is in the blood, as it literally feeds and nourishes every cell within our bodies. Only certain substances are allowed to pass from the bloodstream into the brain, thanks to the protective envelope that is known as the blood-brain barrier. If the blood is thick with cholesterol and triglycerides, the amount of nutrient-rich blood that can pass through the blood-brain barrier decreases. This can result in the brain becoming malnourished over time.

The functioning of the brain also depends upon substances that are referred to as neurotransmitters, which are brain chemicals that act as electrical switches in the brain and are responsible for all the functions of the body. If the brain does not have an adequate supply of neurotransmitters, or the nutrients to make them, it starts to develop something similar to a power failure or a short circuit. If you are trying to recall as specific fact or piece of information and your mind goes blank, it is likely that the above “short circuit” has occurred.

There are many other factors that are involved in the deterioration of the memory. One of the most important is exposure to free radicals, which can cause huge amounts of damage if the memory is unchecked. Alcoholics and drug addicts often suffer a great deal of memory loss, with alcoholics being notorious for huge memory gaps that occur even though they are conscious. Allergies, candidiasis, stress, thyroid disorders, and poor circulation to the brain can also contribute to memory loss, while hypoglycemia can play a role in memory loss as well, as the brain requires that the level of glucose in the blood fall within a specific narrow range. Wide swings in blood sugar levels affect brain function and memory.

The following nutrients are beneficial in dealing with and preventing memory loss: acetylcholine, boron, DMAE, garlic, huperzine A, lecithin granules, manganese, multivitamin and mineral complex, omega-3 fatty acid complex, phosphatidyl choline, phosphatidyl serine, SOD, vitamin A, vitamin B complex, vitamin B3, vitamin C, vitamin E, zinc, acetyl-l-carnitine, l-glutamine, l-tyrosine, Coenzyme Q10, DHEA, DMG, melatonin, NADH, pregnenolone, RNA and DNA, Brahmi, ginkgo biloba, anise, blue cohosh, ginseng, gotu kola, and rosemary.

All of the above mentioned as well as formulas tailored to help improve memory can be found in capsule, table, or power forms. Remember, only look to name brands such as Solaray, Source Naturals and Natures Plus for quality products. Memory vitamins and herbs can be found at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.



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Psyllium Husk Fiber
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Date: March 18, 2009 12:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Psyllium Husk Fiber

Hemorrhoids occur when veins in the anus and in the rectum swell and may protrude from the anus. The word hemorrhoid comes from the word hemo which means blood and rrhoids which means discharging. Hemorrhoids are also known as piles, which comes from the Latin word pila, meaning ball. Hemorrhoids are a lot like varicose veins, as they enlarge and lose their elasticity. This results in a saclike protrusion into the anal canal. Hemorrhoids are not tumors growths. Instead, they can be caused and aggravated by sitting or standing for prolonged periods, violent coughing, lifting heavy objects, and straining at bowel movements. This occurs especially when constipated.

However, bouts of diarrhea accompanied by involuntary spasms can further the problem. Other factors that contribute to the formation of hemorrhoids include obesity, lack of exercise, liver damage, food allergies, and insufficient consumption of dietary fiber. Hemorrhoids are extremely common during pregnancy and after childbirth, with hormonal changes and pressure exerted by the growing fetus are a huge being the main reason. About half of all Americans have had hemorrhoids by the age of fifty, with the incidence increasing with age until age seventy, and then decreasing again.

The most common symptoms of hemorrhoids include itching, burning, pain, inflammation, swelling, irritation, seepage, and bleeding. The bleeding can be startling or even frightening, as it is usually bright red during bowel movements. Although it does signal that something is slightly off in the digestive system, rectal bleeding is not necessarily an indication of a serious disease.

There are three different kinds of hemorrhoids, which are categorized depending on their location, severity, and the amount of pain, discomfort, or aggravation that they cause. These three types include external, internal, and prolapsed.

External hemorrhoids develop under the skin at the opening of the anal cavity. They may form a hard lump and cause painful swelling if a blood clot forms. When an external hemorrhoid swells, the tissue in the area becomes firm but sensitive and often turns blue or purple in color. Most often, this type of hemorrhoid affects younger people and can be extremely painful.

Internal hemorrhoids, which are located inside the rectum, are usually painless, especially if they are located above the anorectal line. This is because rectal tissues lack nerve fibers. However, internal hemorrhoids tend to bleed, with blood appearing to be bright red.

Prolapsed hemorrhoids are internal hemorrhoids that collapse and protrude outside the anus. These are often accompanied by a mucous discharge and heavy bleeding. Prolapsed hemorrhoids often become thrombosed, forming clots within that prevent their receding. Thrombosed hemorrhoids can also be extremely painful.

To our knowledge, hemorrhoids are unique to human beings, with no other creature developing this problem. This can be taken as an indication that our dietary and nutritional habits play a greater role in this disorder than anything else. About 50 to 75 percent of this country’s population develops hemorrhoids at one time or another, with many people being unaware of them. Hemorrhoids can occur at any age, but they tend to become more common as people grow older. Those younger people, pregnant women, and women who have had children seem to be most susceptible, with heredity also playing a part in the tendency to develop hemorrhoids. Although hemorrhoids can be quite painful, they usually are not a serious threat to our health.

The following nutrients can help prevent and treat hemorrhoids: calcium, vitamin C with bioflavonoids, vitamin E, vitamin B complex, Coenzyme Q10, DMG, garlic, potassium, shark cartilage, vitamin A, and vitamin D3. Additionally, the following herbs are also beneficial: aloe vera gel, bayberry, goldenseal root, myrrh, white oak, comfrey root, elderberry, yarrow, witch hazel, buckthorn bark, collinsonia root, parsley, red grape vine leaves, and stone root.

Looking at that list one might think wow that could be expensive. Fortunately, the single most important factor to prevent hemorrhoids is fiber. Adding dietary fiber to ones diet can eliminate constipation and all the complications that follow with bowel problems. Fiber supplements can be an easy solution to the lack of fiber on ones diet. Psyllium husk is a natural fiber that can be taken daily to help alleviate constipation and is relatively inexpensive. Fiber supplements are available at your local or internet health food store.

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Migraines
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Date: February 21, 2009 12:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Migraines

Migraines are severe, throbbing headaches that may or may not be accompanied by nausea, possibly with visual disturbances and other symptoms. Migraine incidences have increased by 50 percent within the last twenty years, with an estimated 25 to 30 million people suffering from them in the United States. Three out of four of these 25 to 30 million are women, with up to 24 percent of women experiencing at least one migraine in their lives and only 12 percent of men getting migraines. Migraine headaches are one of the most severe types of headache.

Research has described migraines as vascular headaches, as they involved excessive dilation or contraction of the brain’s blood vessels. Current research, however, gives other clues. The inflammation involved in migraines is most noticeable in the meninges, which surround the brain and the spinal cord. However, the inflammation of the meninges is not what leads to the pain of migraine, but instead abnormal nerve activity. Stimulation of the trigeminal nerve, which goes from the brain to the head and face, triggers the release of substances that are known as calcitonin gene-related peptides. These induce inflammation and send messages to pain receptors in the meninges. Some researches even liken migraines to meningitis in some ways, as the symptoms are very similar. However, meningitis is caused by viral or bacterial infection.

Migraines can occur anywhere from once a week to once or twice a year, often running in families. One factor that may contribute to the higher incidence of migraine in women may be fluctuations in the level of the hormone estrogen, as women typically get migraines around the time of menstruation, when estrogen levels are low. Most often, migraines occur in people between the ages of twenty and thirty-five, seeming to decline with age. Children can also suffer from migraines, with pain tending to be more diffuse, rather than localized. Migraines can first show up in childhood as colic, periodic abdominal pain, vomiting, dizziness, and severe motion sickness, rather than as headaches.

There are typically five phases in a migraine. The first phase beings a day or so before the onset of a headache, as changes in mood, problems with memory, an alteration in one or all of the five senses, and speech problems occur. Secondly, some people will see flashes or patterns of light and experience numbness of the hands and mouth just before the headache. This is called an aura, and is a common sign of a classic migraine.

Those migraines that occur without auras are called common migraines. The third phase occurs when the headache starts with a severe, throbbing pain occurring on one or both sides of the head and can also move from side to side. Nausea can also set in this phase, along with tenderness in the neck and scalp, sensitivity to light, and possibly immobilization due to pain. The fourth phase occurs when the headache dissipates, although nausea may linger. During the fifth phase, the person may feel tired and lethargic, simply wanting to sleep.

A variety of things can trigger a migraine in an individual who is susceptible, including allergies, constipation, stress, liver malfunction, too much or too little sleep, emotional changes, hormonal changes, sun glare, flashing lights, lack of exercise, and changes in barometric pressure. Dental problems and low blood sugar can also be factors, while other underlying causes such as genetic factors, chemical imbalances in the brain, poor nutrition, and the overuse of painkillers can cause an individual to be susceptible to migraines. Block Migraines with vitamins and herbs.

The following nutrients are recommended for preventing and dealing with migraines: calcium, magnesium, Coenzyme Q10, DMG, DLPA, essential fatty acid complex, 5-HTP, a multivitamin and mineral complex, rutin, vitamin B complex, garlic, quercetin, taurine, vitamin C with bioflavonoids, cordyceps, feverfew, ginkgo biloba, cayeene, chamomile, fumitory, ginger, peppermint, rosemary, valerian, willow bark, and wormwood.

If you are experiencing migraines, consult your doctor before starting vitamin supplements. Vitamin supplements are natural and feed the body to make it stronger and capable of fighting the diseases it may come up against, but medications prescribed by your doctor can conflict with certain vitamins and herbs and a doctors consultation is needed when taken with medications. A source of natural vitamins are available at your local or internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Hay Fever
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Date: February 19, 2009 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hay Fever

Hay fever, which is an allergy to proteins in the pollen of trees, grasses, some plants, or mold, affects the mucous membranes of the nose, eyes, and air passages. Symptoms of hay fever include itchy, red eyes; watery discharge from the nose and eyes; sneezing; fatigue; and nervous irritability. Many of the symptoms of hay fever can be confused with those symptoms of the common cold. However, allergies cause a distinctive clear, thin nasal discharge, whereas secretions that come from colds are usually thick and yellow-greenish as the illness progresses. Colds are also associated with mild fever and are usually gone within a week. On the other hand, allergy sufferers often feel wiped out for many weeks.

At least 50 million Americans suffer from seasonal sneezes, runny nose, and itchy eyes that come with hay fever. There happen to be three seasons of hay fever which are distinguished by the different pollen present at these different times of the year. Tree pollen appears first, usually between February and May, depending on the climate. When trees, weeds, grass pollens, and people are out at the same time, the biggest problems arise. This usually occurs later in spring and in summer. The fall is the season for ragweed pollen. Depending on which pollen or pollens an individual is allergic to, hay fever may be present at any or all of these times.

In more detail, the following is a summary of the types of plants according to the times of year they are most likely to cause problems. Alder, hazelnut, and elm trees cause the most problems in February through May, while birch, maple, and oak trees are problematic in March through June. Beech and spruce trees bring about issues in April through June, while horse chestnut trees are responsible for causing problems in April through August. In April through September, Asters, pine trees, plantain, sorrel, stinging nettle, and various grasses are responsible for bringing about allergies. Buttercups are problematic in May through July and Goosefoot is an issue in June through September. In July through September, mugwort seems to pose a problem.

Those people who suffer from hay fever also often suffer from other atopic disorders like asthma and dermatitis. Those people who suffer from hay fever symptoms throughout the year are said to have perennial rhinitis, which can be caused by animal hair, dust, feathers, fungus spores, molds, and/or some other environmental agent. It should be noted that a susceptibility to hay fever tends to be an inherited condition. Those people who are most prone to allergies are often aware of the time of year and conditions under which they are most sensitive. A RAST test can easily be done and provide reliable results for a definitive diagnosis.

The following nutrients are beneficial for hay fever: bromelain, Coenzyme Q10, Quercetin, raw thymus, vitamin A, vitamin B complex, vitamin C with bioflavonoids, proteolytic enzymes, zinc, calcium, magnesium, garlic, kelp, manganese, Pycnogenol, SOD, and vitamin E. Additionally, the following herbs have been noted to be helpful: alfalfa, chlorophyll, vitamin K, eucalyptus oil, eyebright, lady’s mantle, goldenseal extract, horehound, mullein leaf, stinging nettle, wild cherry bark, turmeric, nettle leaf, and noni juice.

In conclusion, discovering your allergic substance is the first step to recovery. When you can narrow down what is the cause then you can combat the problem with vitamins, herbs, and dietary changes. Your local or internet health food store has a large selection of herbal and homeopathic remedies for hay fever symptoms.



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What is Alpha Lipoic Acid?
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Date: July 18, 2008 12:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Alpha Lipoic Acid?

You can be sure that a supplement has some remarkable therapeutic possibilities when it makes headlines on the five o’clock news. A recent experiment which showed the conditions of rats that had been fed a diet that was totally deficient in vitamin E tested alpha lipoic acid, which caused the rats to return to full health even though no vitamin E was replenished. The results of this test are profound, as giving these rats an alpha lipoic acid caused existing stores of vitamin E that the body was previously unable to use to be regenerated.

Alpha lipoic acid is a vitamin-like antioxidant that has been used in Europe for a long period of time. It has recently emerged as an extremely impressive therapeutic agent that scavenges free-radicals. Recent studies have suggested that it has the ability to stop some degenerative diseases, the oxidative process of aging, and restores the health of diseased organs. Additionally, it has the ability to make up deficits of vitamin E or C and could potentially be one of the best treatments that have emerged for diabetes. Alpha lipoic acid (ALA) is considered to be more potent than vitamins E and C, as well as Coenzyme Q10. Unlike other antioxidants, ALA has properties that make it superior because it is able to replace certain nutritional supplements, while potentiating others, and inhibiting tissues from deterioration that is associated with diseases. This supplement is also both fat and water soluble, which allows it to protect lipid and aqueous cell structures.

Alpha lipoic acid is a compound that is synthesized in small amounts in the body, but can also be supplied from food or supplement sources. A vitamin-like substance, it contains sulfur and also plays a crucial role in energy reactions. It can be found in liver, yeast, spinach, organ meats, broccoli, red potatoes, and red meat. When it is orally ingested, alpha lipoic acid is not compromised in the GI tract or the liver.

Numerous studies have been conducted on ALA, all of which confirm its positive effect on metabolic processes, with recent clinical tests supporting its ability to enhance free-radical protection, slow the aging process, and guard against a variety of degenerative diseases. ALA was discovered in the 1930s, where it was originally classified as a vitamin, and later categorized as an essential coenzyme when scientists discovered that it was involved in the energy processes of cell mitochondria. It wasn’t until 1988 that scientists found that it also has powerful antioxidant effects.

Alpha lipoic acid is important because it protects us from free-radicals which are present in a body as a result of the number of toxic substances such as auto exhaust, tobacco smoke, pollution, preservatives, and additives that we are exposed to on a daily basis. These free radicals can actually accelerate the aging process, causing premature tissue breakdown to occur. Additionally, our environment will continue to surround us with these pollutants that create free radicals.

There are things we can do to minimize our health risks, which include exercising, eating nutritiously, and not smoking. However, these measures are rarely enough to decrease our risk for certain degenerative disease a substantial amount. ALA is beneficial because it scavenges oxidants that are left behind and helps to convert carbohydrates, fatty acids and protein to energy that is needed to drive muscle movements.

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Supports Healthy Blood Pressure
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Date: April 18, 2008 03:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supports Healthy Blood Pressure

  • A comprehensive Bio-Aligned Formula™ that can help maintain blood pressure already within the normal range, when used as part of a healthy diet and exercise plan.
  • A complex array of 35 nutrients, botanicals and special ingredients provides balanced support for blood pressure.
  • Supports two of the most important SystemiCare™ metabolic systems identified by Source Naturals as critical for your optimal health: Heart/Circulation (including healthy blood vessels, blood flow, homocysteine levels, and blood lipid regulation) and Antioxidant Defense.

3 tablets contain:
(Vitamin C (as ascorbic acid) 45 mg
Vitamin D-3 (as cholecalciferol) 240 mg
Vitamin B-6 (as pyridoxine HCl) 24 mg
Folate (folic acid & calcium folinate) 480 mcg
Vitamin B-12 (as methylcobalamin) 600 mcg
Magnesium (magnesium oxide, chelate & succinate) 240 mg
Selenium (as L-selenomethionine) 120 mcg
Potassium (as potassium citrate) 59 mg
L-Arginine (as L-arginine HCl) 1.44 g
L-Citrulline 360 mg
Hibiscus Flower Ext (20% total acids) 120 mg
gamma-vitamin E Complex 90 mg
L-Taurine 60 mg
Masson Pine Bark Extract(95% procyanidolic value) 60 mg
Garlic Clove 60 mg
Freeze Dried White Onion Bulb 60 mg
Arjuna Bark Ext (0.5% arjunolic acid) 60 mg Ashwagandha Root Extract(5% withanolides) 60 mg
Forskohlii Root Extract(ForsLean®) (20% forskohlin) 60 mg
Guggul Extract (10% guggulsterones) 60 mg
Grape Seed Extract (Proanthodyn™) 48 mg
Chinese Salvia Root Extract (MSV-60®)
(60% magnesium salvianolate B) 45 mg
Ginkgo Leaf Extract (50:1)
24% Flavoneglycosides 36 mg
Hawthorn Berry Extract (4:1) 30 mg
Hawthorn Leaf and Flower Extract (4:1) 30 mg
Olive Leaf Ext. (15% Oleuropein) 30 mg
Trimethylglycine (TMG) 30 mg
Total Resveratrols (from Polygonum cuspidatum) 24 mg
Nattokinase (NSK-SD™) 21 mg
Coenzyme Q10 18 mg
Tocotrienol Complex (Tocomax®) 12 mg
Lycopene 3 mg

Suggested Use: 3 tablets mid-morning and 2 tabs mid-afternoon between meals on an empty stomach.

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Health And Applications Of Coenzyme Q10
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Date: April 17, 2008 02:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Health And Applications Of Coenzyme Q10

Coenzyme Q10 is a critical cofactor in the biological energy process. It is a powerful antioxidant and plays a vital role in our health and wellness. Coenzyme Q10 is involved in many disease states, consuming adequate Coenzyme Q10 can ensure that one maintains good health which can reduce the risk of chronic disease such as the ones listed below:

Cardiovascular disease

  • Cardiomyopathy
  • Angina pectoris
  • Arrhythmias
  • Mitral valve prolapse
  • Hypertension
  • Atherosclerosis
  • Cardiotoxicity (drug induced)

Neurodegenerative disease

  • Huntington’s disease
  • Parkinson’s disease
  • Amyotrophic lateral sclerosis (ALS)

Neuromuscular disease

  • Mitochondrial cytopathies (melas, merrf, ect.)
  • Muscular dystrophy
  • Ataxias
  • Chronic obstructive pulmonary disease
  • Asthma
  • Immune disorders
  • Periodontal disease
  • Chronic fatigue syndrome

Many prescription drugs can cause Coenzyme Q10 to deplete especially statin drugs (cholesterol meds). Beta blocking drugs and anti-diabetic drugs can also leach the body of vital Coenzyme Q10 which could lead to the above diseases if left un-checked over time.

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Ubiquinol
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Date: April 16, 2008 01:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Coenzyme Q10 is an important cofactor that is found in nearly every cell of the body. Coenzyme Q10 is naturally produced by the body as well as attained through the foods we eat or in supplement form. With out it, every cell in our body could not produce energy to function and we would die. Coenzyme Q10 has the capability to regenerate antioxidants, protecting cells and DNA from oxidative stress which naturally occurs in the body every day.

Some may say that Coenzyme Q10 exists in only one form, but in fact this substance exists in at least three forms in the body naturally. These three forms are CoQ ubiquinone, CoQH ubisemiquinone and COQH2 ubiquinol all of which are metabolically active forms of Coenzyme Q10.

Ubiquinone has been commercially available for more than 30 years normally consumed orally, but recently stable forms of Ubiquinol have been made available for consumption which is of great interest by many researchers. The former ubiquinone when ingested had to be reduced by an enzymatically driven conversion from ubiquinone to Ubiquinol in the digestive tract. This conversion is done by the transfer of electrons effectively reducing the Coenzyme Q10 to a more usable form Ubiquinol.

Once Ubiquinol is produced the body can more easily manufacture ATP which is directly used by cells for cellular energy. In young individuals, 90 percent of Coenzyme Q10 found in the blood is in the Ubiquinol form. This being the case, the old form (ubiquinone) was less absorbable then the newer Ubiquinol that can go right to work in the body. Ubiquinol is considered the strongest lipid soluble antioxidant that is biosynthesized, providing an active defense against oxidative stress that damages, cells, proteins, lipids, and DNA.

Some scientists believe that cellular damage from free radicals cause our bodies to age. The older we get the less our bodies produce Coenzyme Q10 which in its self is an antioxidant and restores other antioxidants in the body to fight the war against free radicals. Eating foods rich in antioxidants and or supplementing with antioxidants may slow the aging process.

With age, disease, and some prescription medications, the old form of Coenzyme Q10 can not easily follow the process of absorption in the intestinal tract where it is reduced and shuttled through the lymphatic system into the circulatory system (blood). This is why Ubiquinol was so highly sot after. Ubiquinol is already reduced, the preferred form Coenzyme Q10 the body wants to circulate and retain.

When one ages, energy levels always drop and one tends to slow down and feel tired sooner in the day, this may be because of a drop in Coenzyme Q10 in the blood. Many recent studies suggest that the plasma Ubiquinol ratio is reduced in response to cardiovascular disease, neurodegenerative disease, cancer, fatigue and especially in type-2 diabetes. Supplementing with Ubiquinol can help restore plasma levels and boost ones energy levels and possibly slow diseases.

To sum it up, if you are over 45, suffering from a degenerative disease or cancer, feel tired and run down, or taking prescription medications, conventional Coenzyme Q10 is not what you want to take to elevate plasma levels. Ubiquinol is needed because the body can not adequately produce the most abundant form of Coenzyme Q10 in he blood (Ubiquinol). So for those who want to maintain health and wellness, look for Ubiquinol in their local health food store.

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Ubiquinol Reduced CoQ10
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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Alpha Lipoic Acid is a Powerful Antioxidant
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Date: February 15, 2008 02:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Alpha Lipoic Acid is a Powerful Antioxidant

The discovery of alpha lipoic acid at the University Of Texas Chemistry Department in 1951 was not heralded with trumpets of joy at the revelation of such a powerful antioxidant, but was instead largely ignored. This is largely due to the biochemistry involved not being fully understood at that time, but by the 1980s it was a commonly used supplement, recommended for several medical conditions.

Chemically, the substance is a 5-membered cyclic disulphide with a carboxylic acid grouping. Biochemically, it’s extremely powerful antioxidant properties are largely due to the fact that it one of those rare active molecules that are soluble in both water and fats, and in fact is the only such antioxidant currently know. One of the properties that this ability enables it to possess is to cross the blood-brain barrier, and apply antioxidant propertied to the brain.

Antioxidants are essential to human life in that they destroy free radicals. These are compounds with free unpaired electrons that destroy human body cells in their hunt for electrons to pair with. Electrons come in pairs in organic animal tissue, just as they do in organic compounds. However, under certain circumstances this pairing can become destroyed, leaving a molecule with one of its electrons without a partner.

The factors that lead to this situation are many and varied, and our own biochemistry can produce free radicals during the normal chemical processes of life. However, pollution can also lead to the oxidation processes that create free radicals, common such pollutants being cigarette smoke, vehicle exhaust fumes, pesticides and the like. Excessive exposure to the UV content of sunlight can also create free radicals as can eating barbecued and smoked foods, and exposure to carbon monoxide and peroxides. Even the biochemical conversion of glucose to energy in our bodies creates free radicals.

These free radicals can destroy body cells, including DNA, and can create conditions such as premature aging due to destruction of skin cells, destruction of brain cells, strokes, cancers, diabetes, atherosclerosis due to oxidation of LDL cholesterol that deposits in the main arteries of the body, stiffening of the joints and many other undesirable conditions.

Free radicals are destroyed rapidly by antioxidants: the reaction is very rapid and most are destroyed immediately they are formed before they can do harm. Fortunately, if your diet is well maintained, the body possesses many antioxidants such as vitamins A, C and E, and other substances such as Coenzyme Q10, flavanoids, xanthenes, polyphenols and carotenoids. Many of these are found in highly colored foods, and if your food is brightly colored, it should contain a good supply of antioxidants.

However, the problem with all of these is that they are either fat and oil soluble or water soluble, which means that they can either be freely carried round the body by the blood or have to be emulsified by the bile and transported via the lymphatic system that places restrictions on their effectiveness in certain organs of the body. The fact that alpha lipoic acid is soluble in both water and fats enables it to be carried to all parts of the body and to every organ, and can cross water/fat barriers that other antioxidants cannot do.

It can therefore be carried via the blood to the brain and carry out an essential antioxidant function within our brains. It took a long time for this property of ALA to be recognized and its consequent health benefits understood. It is, in fact, the ideal antioxidant. The substance provides many known benefits to the body due to its antioxidant properties and also helps the body to generate the maximum possible amount of energy from the blood glucose and thus improve the energy balance of your body.

However, it is with its antioxidant properties that we are most concerned here. One of the benefits of these properties is its effect in holding back the visible effects of aging on your body. Because it is both water and fat soluble, alpha lipoic acid can help destroy free radicals in every part of your skin; the areas served by the blood and the fatty and oily secretions are protected simultaneously by the same strong antioxidant. The end result is a reduction in the destruction of the cells through the dermis and epidermis and a reduction in the degree of wrinkling with age.

Its antioxidant effect in the brain renders ALA in great demand for reducing cognitive impairment with age. In fact studies have indicated that alpha lipoic acid can improve memory and brain function in the aging and the elderly. This effect appears to be increased by the synergistic combination of alpha lipoic acid and acetyl-L-carnitine that work together to prevent cognitive decline in the brain through the effect of free radicals.

There is evidence that during a stroke, ALA works synergistically with vitamin E to reduce the effect of free radical damage on the vulnerable brain cells, and so reduce the longer term effects of the stroke. Together with ALC, it also reduces oxidative stress on the mitochondria of cells and in so doing helps once again to reduce the effects of aging, and maintain the body’s capacity to generate energy from blood glucose.

Cardiovascular disease is the main killer of the western world, largely due to our diets, and this is especially true of the USA. Although Americans appear unable to change their unhealthy diet, alpha lipoic acid and acetyl-L-carnitine can be used to offset much of the damage done. ALA reduces the development of atherosclerosis through its antioxidant properties and the reduction of the adhesion of monocytes to the artery walls.

LDL trapped in the wall of the artery can be oxidized and enable monocytes to also enter under the surface of the arterial wall, where it changes into macrophages and ingests the oxidised LDL, causing the plaque that forms atherosclerosis. As the plaque thickens, the artery becomes increasingly restricted until the blood flow is significantly reduced or even stopped, causing cardiac failure or a stroke.

Alpha lipoic acid can prevent this free radical oxidation from occurring by destroying them before they act on the low density lipoprotein (LDL). Acetyl-L-carnitine works with the ALA to achieve this, as does another substance known as carnosine. Between them, these three musketeers work to keep your arteries clear and your brain functioning as it should, though it is the ALA that is most powerful due to its oil and water solubility properties.

Although alpha lipoic acid is available as a supplement, either alone or in combination with acetyl-l-carnitine, it is also available from natural food sources. It is particularly rich in offal such as heart and kidney, and also in broccoli, spinach and brewer’s yeast. It is also available in beef, and it is here that burgers can perhaps repay some of the damage that it causes. However, it is not a recommended source since burgers still cause more damage to your health than any of their constituent nutrients can allay.

Like any other supplement, you should seek medical advice before taking any substance if you have a health condition. Nevertheless, the benefits of alpha lipoic acid are such that it is difficult to see it doing anything but good. However, please consult your physician if are taking other drugs.

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Seniors Need More Than a Multiple with Only 100 Percent of the RDA
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Date: January 21, 2008 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Seniors Need More Than a Multiple with Only 100 Percent of the RDA

The aging process is a gradual one. That might seem obvious, and it is, but it is the fact that it is gradual that causes people not to notice the small but significant changes in their body that are taking place. Aging is more than just the oxidation of skin cells that cause them to wrinkle, but involves specific functional cell changes, such as their ability to multiply.

As this slows down the immune system is affected, and we find it more difficult to recover from injury and disease. Oxidation becomes more prevalent and free radicals become more common as the natural antioxidants of our bodies become overwhelmed. We are less able to recover from the effects of environmental stress, such as UV radiation from the sun, pollution and the effects of heat. We find it increasingly difficult to deal with a lack of nutrition or toxins in our food from pesticides. In short, we become less capable of dealing with attack by invaders, but do not notice this gradual lack of immune response.

Age also affects our joints from the vertebrae in the neck to the joints of our toes. The net result is a compression of the bones that causes a reduction in height. We also develop more body fat and less muscle tissue, which is a significant consideration in planning the nutritional needs of the elderly. However, of more critical importance when discussion the nutritional needs of our aging population is the possibility of malabsorption.

Malabsorption is an inability of the digestive system to absorb nutrients from food, and occurs in people of any age although it tends to be more prevalent in seniors. It is predominantly due to a dysfunction of the liver, the pancreas or the small intestine that are the three major physical components of the human digestive system.

The liver produces bile that is needed to process the fats in your food, and if the bile is not delivered to the small intestine, then malabsorption is possible. The same is true of the enzymes that are produced by the pancreas These enzymes are important components in the biochemistry that allow us to absorb nutrition from our food, and since most of this absorption occurs in the small intestine, this too is essential for proper absorption. When any of these three are reduced in efficiency, as they are with advancing years, then malabsorption will occur.

When this occurs in seniors, however, it is essential that a multiple supplement with more than 100% of the RDA (Rcommended Daily Allowance) is used. This type of nutritional deficiency can be very serious at an age when so many normal biochemical processes are slowing down, and it is important that steps are taken to avoid the serious problems that can arise.

The immediate symptoms of malabsorption are diarrhea and weight loss, although the more serious longer term effects are anemia due to a deficiency in folic acid and iron and a reduction in the blood’s ability to form clots due to a deficiency in vitamin K absorption. There are others, but not all problems associated with aging are actually due to malabsorption, or even with aging.

Many of the problems associated with aging are now believed to be connected with the patient’s lifestyle and diet. Heart disease such as atherosclerosis is now known to begin earlier in life, as are many other conditions once believed to be associated with age. A loss of cognitive ability can be age related, but also due to cigarette smoking and excessive alcohol consumption. However, irrespective of all this, it is essential that the aged are provided with vitamin and mineral supplements offering more than 100% RDA.

Calcium is of particular importance for older women who are particularly prone to osteoporosis due to malabsorption of calcium from their food. At least 1000mg daily should be taken, and extra magnesium and vitamins A and E will also be necessary since they are needed for the proper absorption of calcium. The extra does not infer that all of the supplement will be absorbed, but that enough should be to help reduce the possibility of bone density problems.

The elderly are particularly prone to vitamin B deficiencies, particularly of vitamin B12, due to absorption problems and a good vitamin B complex supplement is needed. Chromium too can be seriously depleted in the aged, and this mineral is necessary to enhance the activity of insulin. It is also believed to play a part in the metabolism of carbohydrates, proteins and fats. There are no known consequences of an excess of chromium so a good supplement can be provided. It is believed that vitamin B and chromium together are required for cardiovascular and neurological health that are so important as we age.

One important supplement for the elderly is Coenzyme Q10. Many older people are prescribed drugs such as statins for the treatment of high cholesterol levels. Statins work by depressing the biochemical synthesis of cholesterol by blocking the action of mevalonate, and this is known to interfere with the metabolism of Coenzyme Q10, otherwise known as ubiquinone.

CoQ10 is essential in allowing the production of energy within the cell mitochondria by allowing electron transfer back and forth between NAD and NADH to allow the production of adenosine triphosphate (ATP). A supplement of this important enzyme is therefore essential in maintaining the energy levels of the aged who are being prescribed statins.

Almost 20% of the elderly on prescription drugs are also taking herbal remedies and supplements, and there could be an interaction between them. Anybody taking prescription drugs should consult their physicians before taking natural remedies or any form of supplement, and this is particularly true of the elderly.

However, where the elderly are safely taking a vitamin and mineral supplement, it is extremely important that this contains more than just the RDA. Absorption problems are very common in the elderly, and this excess can make sure that they receive more than they would otherwise, if not the whole recommended dosage of the particular substance involved. Better safe than sorry, especially where an excess is not known to cause harm.

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Give Your Health A Boost With Silica Hydride A Powerful Antioxidant
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Date: January 18, 2008 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Give Your Health A Boost With Silica Hydride A Powerful Antioxidant

Hydride ions are strong proton acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.

A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.

Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.

This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.

The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.

This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.

An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.

Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.

In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.

Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.

Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.

Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.

If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.



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Your Mouth Has A Lot To Say About Your Health
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Date: January 10, 2008 08:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Your Mouth Has A Lot To Say About Your Health

For those of you have read every magazine article on improving your health and sex life, tried every trick suggested to you, and still have not found the solution, you may be missing one fact that most people don’t even consider towards improving their love life with better health. A woman’s sexuality has to do with a great variety of factors including both physical and emotional issues. Physical influences include hormonal imbalances, which play a major role. Most women experience the rage of this imbalance during pre and post menopause, as well as our menstruation cycle, commonly known as PMS. But most people have not considered one other important physical factor that is affecting their sexual mood, which is gum disease. Although this connection is rarely talked about and may seem odd at first, it becomes obvious how it all works when you learn the science behind it.

Throughout the different stages of our lives, our hormones fluctuate greatly. From puberty to pregnancy and menopause, many of our tissues are affected, which includes our gums. The gums can swell up, bleed easily, and even change color during times of related hormone events. Gum disease may be prevented with Coenzyme Q10 supplementation. Once the hormone balances, the hormones often do not go back to their healthy state automatically. If you practice good oral hygiene, your gums will go back to normal, but if not, it will stay the same or get worse with out proper nutrition and Coenzyme Q10.

Most people never realize that the slight bleeding of their gums during pregnancy or pre-menopause has anything to do with their hormones and nutritional deficiencies. Slight bleeding, red gums, and swelling are all signs of the inflammation that is associated with gum disease. Most people do not pay attention to the signs of inflammation when it occurs in the mouth, as gum disease affects 23 percent of women ages 30-54 and 44 percent of women ages 55-90. Proper nutrition may help reduce the number of individuals affected by gum disease.

Even the beginning stages of gum disease, which are known as gingivitis, can greatly impact your mood and health. If it is not treated, gingivitis will advance into chronic inflammation, leaving devastating results on your health. When your gums are not healthy, a great amount of events involving chemicals takes place both locally and systematically. These chemical changes trigger your immune system to respond, leaving inflammation on the gum tissue. During inflammation, immune cells release substances called inflammatory cytokines, which boost immunity but also induce dark moods in some people. If these cytokines stay too high for too long, they can even potentially trigger depression. Chronic inflammation leaves your body feeling tired and burned out. Unfortunately, a lot of people who have gum disease do not even know they have it. Except for the sign of slight bleeding when flossing or brushing, an unsuspecting person may not be aware there is tissue breakdown until it’s too late.

The solution to the situation is really simple. Taking 100 to 400 milligrams of Coenzyme Q10 to boost the immune system and help the body reduce its production of cytokines as well as boost energy. Coenzyme Q10 can improve periodontal health so be sure to consider the health of your mouth as an important part of your overall health. When you feel healthy, your sex drive is also healthy. If you’re feeling run down and have no interest in sex, make a visit to your dentist and have your gums checked. There is no excuse to not get regular dental check-ups and visit your local health food store to practice good oral hygiene and boost over all health.



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Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver
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Date: December 18, 2007 05:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver

Coenzyme Q10 Ultra Potent 400 mg!

Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver

  • A crucial component in the cellular energy production cycle.
  • Research indicates that supplementation with this nutrient may support normal heart function, provide antioxidant protection and support gum health.
  • One of the highest potency CoQ10 products available, for serious nutrition and powerful protection.

1 softgel contains: Coenzyme Q10 (ubiquinone) 400mg

Ubiquinone Coenzyme Q10 is a highly absorbably form of CoQ10. CoQ10 is a powerful antioxidant to help fight oxidative stress which can cause premature aging. CoQ10 is a critical enzyme for cellular energy for all muscles in the body, especially the heart muscle that beats millions of times with out stopping in a lifetime. CoQ10 can help boost brain function, boost immunity, and boost liver function.

For those with gum disease, Coenzyme Q10 can support healthy gums and teeth. Have you had your Coenzyme Q10 today?



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Support Healthy Joint Function With Discount Vitamins
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Date: November 22, 2007 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Support Healthy Joint Function With Discount Vitamins

The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime.

Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones.

Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain.

Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue.

A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders.

A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints.

The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover.

Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids.

Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks.

Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage.

Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement.

It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that.

That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results.

Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density.

There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium.

You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.



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Ubiquinol
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Date: October 24, 2007 11:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Benefits

Ubiquinol has powerful antioxidant actions in target cells *

 

Although ubiquinone (oxidized Coenzyme Q10) and ubiquinol (reduced Coenzyme Q10) are kept at a constant ratio within the body, the majority of the total Coenzyme Q10 pool is made up of ubiquinol.  In fact, when ubiquinone is taken orally, much of it appears to be rapidly converted into ubiquinol. 1,4 Ubiquinol functions as a potent antioxidant in humans, including in low-density lipoproteins (LDLs) where it protects them from oxidative damage.1,4,5 The Coenzyme Q10 molecule can be found in all membranes throughout cells.6 It appears to works in conjunction with both vitamin E and vitamin C to provide antioxidant actions throughout the body.7

 

Coenzyme Q10 supports mitochondria to enhance cellular energy production*

 

Coenzyme Q10, with its widespread distribution throughout the body, plays a crucial role in mitochondrial physiology as a critical member of the electron transport chain. This transport chain, which is part of cellular respiration, leads to the formation of adenosine triphosphate (ATP), our body’s primary energy source.  Levels of this key nutrient may decline as a healthy person ages.7,8  Animal studies have found that supplementation can restore normal levels in certain tissues 6, and human studies suggest that supplementing with this enzyme may have increased benefits when a person has depleted levels. 7

 

Coenzyme Q10 supports healthy heart functioning*

 

Concentrations of Coenzyme Q10 are understandably high in the heart as these muscle cells require high levels of energy to constantly function optimally. A number of studies (both animal and human) strongly suggest that Coenzyme Q10 supplementation is supportive for healthy heart functioning and for maintaining cardiovascular system health.7,9

 

Ubiquinol has been studied for safety and bioavailability in humans*

 

A recently published single-blind placebo-controlled study in healthy subjects found no safety concerns in people who took Kaneka’s QH ubiquinol supplement orally at doses of up to 300 milligrams daily for up to four weeks.4 Single oral doses of either 150 milligrams or 300 milligrams were given to fifteen healthy men and women, and standard laboratory testing (including hematology, blood chemistry, and urinalysis) as well as physical examination and electrocariography (EKG) results showed no clinically significant changes when tested two days after supplementation as compared to before the taking the supplement. In addition to the single dose study, 80 healthy volunteers were given either placebo, 90, 150 or 300 milligrams of ubiquinol each day for four weeks, and again no clinically significant differences were seen in any of the testing parameters after two and four weeks of supplementation, nor were there differences two weeks after discontinuation of the supplement.  By monitoring levels in the blood, the authors found that ubiquinol was well absorbed.4

 

Studies in several animals also reveal no concern of toxicity in doses of ubiquinol up to 200 milligrams per kilogram of body weight for up to thirteen weeks.4 When compared to humans, this dose level is enormously higher than the recommended doses.  Supplementation with ubiquinol appeared to be safe at even higher levels (up to 600 milligrams per kilogram body weight) in a study using a different animal. In vitro assays additionally found no safety concerns for the use of ubiquinol, as it was found to be non-mutagenic and did not cause damage to chromosomes in cells.

 

Safety

Suggested Adult Use: Take one softgel daily with food, or as directed by a nutritionally informed physician.

 

Scientific References

1.    Mohr, D., V.W. Bowry, and R. Stocker, Dietary supplementation with Coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta, 1992. 1126(3): p. 247-54.

 

2.    Weber, C., et al., Effect of dietary Coenzyme Q10 as an antioxidant in human plasma. Mol Aspects Med, 1994. 15 Suppl: p. s97-102.

 

3.    Okamoto, T., et al., Human serum ubiquinol-10 levels and relationship to serum lipids. Int J Vitam Nutr Res, 1989. 59(3): p. 288-92.

 

4.    Hosoe, K., et al., Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol, 2007. 47(1): p. 19-28.

 

5.    Stocker, R., V.W. Bowry, and B. Frei, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci U S A, 1991. 88(5): p. 1646-50.

 

6.    Crane, F.L., Biochemical functions of Coenzyme Q10. Journal of the American College of Nutrition, 2001. 20(6): p. 591-598.

 

7.    Jones, K., et al., Coenzyme Q-10 and cardiovascular health. Alternative therapies, 2004. 10(1): p. 22-31.

 

8.    Schulz, C., et al., Comparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). Int J Food Sci Nutr, 2006. 57(7-8): p. 546-55.

 

9.    Coenzyme Q10. Monograph. Altern Med Rev, 2007. 12(2): p. 159-68.

 



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Natural Coenzyme Q10 (Ubiquinone)
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Date: July 27, 2007 02:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Coenzyme Q10 (Ubiquinone)

CoQ-Quick™

Natural Coenzyme Q10 100 mg

• Supports cardiovascular function.

• Vital for the production of ATP, the energy molecule.

• Potent antioxidant.

Addresses six of the twelve SystemiCareTM deep metabolic systems identified by Source

Naturals as critical for optimum health: Energy Production, Circulation/Heart Health, Liver/

Detox, Immunity, Cognition/Nerves, and Antioxidant Defense.

Delicious, natural orange flavor.

One tablet contains:

 

Coenzyme Q10 (ubiquinone) 100 mg

 

Suggested Use: 1 tablet daily with a meal. Not a sublingual tablet. Place tablet on top of tongue and allow tablet to dissolve while lightly pressing tongue against the roof of the mouth. Tablet will disintegrate rapidly. Swallow CoQ-Quick contents after the tablet has disintegrated.



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Active Coenzyme Q10
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Date: July 07, 2007 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Active Coenzyme Q10

Active CoQ10

 

The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.

In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. What is ubiquinol? Is it the same or different from CoQ10?

A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.

 

Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?

A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.

So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.

 

Q. What are the health benefits of CoQ10 and Ubiquinol?

A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.

In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.

 

Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?

A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.

 

Q. How might ubiquinol be important for the heart?

A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.S. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment. Since ubiquinol is the active form of CoQ10, it may be able to overcome the hurdles to providing maximum impact, most importantly, age and genetic related inefficiencies in converting CoQ10 to active CoQ10 (Ubiquinol).

 

And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.

The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.

Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.

The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.

Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.

 

Q. What have been the results of research studies with Ubiquinol?

A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.

Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Should I take CoQ10 or ubiquinol? How much should I take?

A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.

Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.

 

Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological diseases, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagines. The more we study this naturally occurring compound, the more benefits we find. And with this new ability to provide CoQ10 in its active form, ubiquinol, for the first time, even greater benefits may be derived.

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The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
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Date: May 18, 2007 01:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium

The Awesome Foursome: Coenzyme Q10, L-Carnitine,

D-Ribose, Magnesium

 

The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.

 

Coenzyme Q10:

Energy Recycling through the Electron Transport Chain

Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.

Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.

In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.

What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.

Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.

 

L-Carnitine:

Transporting the Cellular Energy Fuel

Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.

 

D-Ribose:

Rebuilding the Cellular Energy Pool

As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.

When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.

Ribose is the only compound used by the body to refill this energy pool.  Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency.  Ribose is made naturally in the cells from glucose.  In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis.  So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.

    Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy.  Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days.  But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose.  Conditions like ischemic heart disease or congestive heart failure fall into this category.  In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.

 

Magnesium:

Switching on the Energy Enzymes

Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism.  Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work.  Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.

    Magnesium deficiency reduces the activity of important enzymes used in energy metabolism.  Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function.  Small changes in magnesium levels can have a substantial effect on heart and blood vessel function.  While magnesium is found in most foods - particularly vegetables - deficiencies are increasing.  Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.

 

Supporting the Links in The Energy Cycle Chain – the Synergy

Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.

The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.

The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.

Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.

These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.

The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.

L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.



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CoQ10 for Heart Health
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Date: March 28, 2007 12:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10 for Heart Health

CoQ10 for Heart Health

 

More than 40% of all deaths in the U.S. are from cardiovascular disease (CVD). You have a greater chance of dying from heart disease than from cancer, AIDS, diabetes, and accidents combined. More than 2,600 Americans die each day of CVD – an average of 1 death every 33 seconds. One in 5 men and women have some form of CVD. If all forms of major CVD were eliminated, life expectancy would rise by almost 7 years.

One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is Coenzyme Q10 (CoQ10).

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. For what health conditions is CoQ10 used?

A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.

 

Q. Why is CoQ10 especially important to heart health?

A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.

 

Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.

 

Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.

In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.

 

Q. What studies support this fact?

A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

 

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

 

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.s. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment.

 

Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?

A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.

 

The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

 

Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.

 

Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?

A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.

 

While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?

A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:

 

1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.

 

2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.

 

3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at Massachusetts General Hospital and Harvard Medical School.

 

4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.

 

Q. How much CoQ10 should I take?

A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.

 

CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

 

Q. What are some other heart-friendly supplements?

A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.

 

Q. What supplements support healthy blood pressure and cholesterol?

A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.

 

Conclusion

CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.

The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.

Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.

 

 



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Neurological Health and CoQ10
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Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.



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Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.
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Date: November 09, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.

For some people the constant tingling in their feet is the worst part. Others feel like their feet are being stabbed or burned, or that their extremities are simply lifeless. All these folks suffer from peripheral neuropathy, nerve damage that afflicts nearly 30% of people with diabetes aged 40 and older. And if the discomforting sensations are not enough, neuropathy can lead to falls, wounds that won’t heal, even amputation.

Untold numbers of individuals have been helped by alpha lipoic acid (ALA), a supplement that European practitioners have used as a standard neuropathy treatment for 30 years. ALA (also known as thioctic acid) assists in the chemical reaction that generates energy within cells. It serves as a universal antioxidant—a substance that can fight tissue-damaging free radicals in both the fatty watery parts of a cell-and helps the body create additional free radical fighters, such as glutathione. ALA can even help regenerate several other antioxidants, including Coenzyme Q10 (CoQ10) and vitamins C and E.

Defying diabetes

People with diabetes need antioxidant protection as much as anyone. Fortunately for them, though, ALA fights this insidious disorder in many other ways.

Diabetes occurs when the body can no longer effectively use glucose (blood sugar), its main energy sources; ALA helps shepherd glucose out of the blood and into cells. It also interferes with glycosylation, a process in which glucose sticks to proteins such as the low-density lipoprotein (LDL) that carries cholesterol through the bloodstream. That’s important because this “sticky” LDL can adhere to arterial walls, creating a major risk factor for heart disease. ALA combined with exercise appears to make insulin, the hormone that controls glucose usage, more effective. What’s more, early research indicates that ALA can deflect another cardio hazard by interfering with the ability of salt to push blood pressure upward (molecular and Cellular Biology 12/03).

ALA Annotations – what is it? Alpha Lipoic acid, a substance the body creates naturally.

What it Does: ALA, a powerful antioxidant in its own right, plays a vital role in the creation and renewal of other antioxidants. It is used to treat peripheral neuropathy; nerve damage caused by diabetes, and is also under investigation for possible therapeutic effects in other disorders, including multiple sclerosis and age-related cognitive decline.

Diabetes doesn’t just attack the nerves and the heart—its effects are felt throughout the body. That’s why scientists are examining whether ALA can tackle other diabetic complications: in lab studies it has forestalled diabetes-related kidney and eye damage. (Check blood-sugar levels regularly when using ALA, especially if you’re taking other glucose regulators.)

Protecting Nerves

While diabetes is one of the most common causes of nervous system damage, it isn’t the only one. In test tube studies ALA has promoted chemical reactions that encourage neurons (nerve cells) to survive and grow; as a result some scientists believe this natural antioxidant may eventually play a role in treating degenerative nerve disorders. Such research is in its beginning stages, but the results are still intriguing. For example, in mice ALA has slowed progression of a disorder that mimics multiple sclerosis in human beings (Journal of Neuroimmunology 3/04) and improved age-related memory loss when used with N-acetyl-cysteine (NAC), another antioxidant supplement (Journal of Neurochemistry 3/03). A number of other conditions that become more common with age may also benefit from ALA, including arthritis and thinning skin.

If you suffer from both diabetes and the nerve damage it causes, ask your practitioner about ALA. It just may help your feet and the rest of you feel happy. –Lisa James



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Lower Cholesterol Naturally!
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Date: October 06, 2006 09:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lower Cholesterol Naturally!

Because of organizations like the American Heart Association (AHA), we’ve learned a lot about cholesterol and how it affects our health. Thanks to these educational organizations, we know that high cholesterol levels can increase our risk for heart attacks and strokes and, by lowering these levels, we reduce these risks as well as keep our hearts and blood vessels healthy. We also know that our cholesterol levels can be improved through exercise, diet, and weight loss.

Although we’ve learned a lot through these educational organizations, there are still a few misconceptions about cholesterol. One of these being that not all cholesterol is harmful. There are both “good” and “bad” forms of cholesterol and a good balance between the two is what is needed for a healthy heart. Because so much emphasis is placed on lowering “bad” cholesterol levels, not enough attention is paid to the benefit of raising “good” cholesterol levels (HDL). Research states that raising HDL levels can provide even greater protection against cardiovascular disease than just simply lowering “bad” cholesterol levels. By raising HDL levels by simply 1%, the risk of heart disease can be lowered by 2% in men and 3% in women. Many studies have shown that low HDL cholesterol levels are an independent risk factor in heart disease. This is extremely important because we’ve learned that despite efforts to change a person’s diet and exercise habits, some people’s cholesterol levels are still unhealthy.

Prescription drugs to lower cholesterol are now available and have been proven by multiple studies to be very successful. The statins’ effectiveness in reducing LDL (“bad”) cholesterol has produced highly significant reductions in heart attacks and strokes. Although these medications do lower cholesterol levels, their side effects must be considered. Statin drugs can cause liver irritation, reduce CoQ10 levels in the body, are associated with myopathy, and are even linked to a rare and sometimes fatal condition called rhabdomyolysis. These drugs also have a relatively small effect on good (HDL) cholesterol levels. Thankfully, there are safe and effective solutions available that can help you manage your cholesterol levels naturally. However, first we must review what we know about cholesterol and heart disease.

Cholesterol is a fat-like substance needed to help digest fats, strengthen cell membranes, make hormones and insulate nerves. Although it is found in every cell of the body, cholesterol is mainly made in the liver, as well as cells lining the small intestine. Even though our bodies make all the cholesterol we need, we also get cholesterol from the foods we eat, such as egg yolks and organ meats. All foods from animal sources contain cholesterol, while plant derived food, including peanut butter and avocado, contains no cholesterol at all.

Cholesterol is important to many functions of the body. However, too much cholesterol in the bloodstream is extremely dangerous. After blood cholesterol reaches high levels, it builds up on the artery walls, and thus increasing the risk for blood clots, heart attack, and stroke. If the cholesterol clogs any of the coronary arteries, the heart’s supply of oxygen and nutrients will diminish, resulting in coronary heart disease, angina, or even heart attack.

Because cholesterol and other fats can’t dissolve in the blood and thereby can’t travel on their own, they have to be transported to and from the cells by lipoproteins. The two major lipoproteins are low density lipoproteins (LDL or “bad cholesterol) and high density lipoproteins (HDL or “good cholesterol”) LDLs carry cholesterol throughout the body to the cells and cause artherosclerosis by clogging up our arteries with fat. On the other hand, HDL prevents the fat buildup by carrying it away from the arteries and to the liver where it can be eliminated. Although high levels of LDL are associated with cardiovascular disease, high HDL can drastically reduce your risk of heart disease. As a result, the AHA has established three guidelines to keep your heart healthy: HDL levels about 40 for men and above 50 for women, LDL levels between 100 and 159, and a total cholesterol (HDL and LDL) of under 200.

Triglycerides are fats used as fuel by the body and a source for metabolism. These levels can fluctuate easily but increased levels are almost always a sign of too much carbohydrate and sugar intake. High amounts of triglycerides make the blood less capable of transporting oxygen and are another factor for cardiovascular disease. Thankfully, the HDL and LDL blend mentioned earlier can safely and effectively lower triglyceride levels.

It has been shown that high levels of HDL cholesterol are inversely related to coronary artery disease risk. However, what people do not know is that there are different subtypes of HDl, including HDL-2 and HDL-3. HDL-3 is produced by the liver and intestines and is responsible for scooping up free cholesterol from the blood vessel walls. The cholesterol carried by HDL-3 is chemically modified, forming a larger-sized subtype, known as HDL-2, or “mature HDL.” HDL-2 transports cholesterol to the liver for processing and elimination, and its molecules are then recirculated in the blood stream. Research has shown that HDL-2 provides more heart-protection because it moves the cholesterol away from arterial walls, and holds a greater number of receptor sites which allows it to carry a larger amount of cholesterol to the liver.

Although many prescription medications have been developed to lower bad cholesterol, there are very few medications that target good cholesterol. Therefore, patients with naturally low HDL cholesterol, who can not alter these levels through diet and exercise, have limited medical options to reduce their risk of heart disease. Multiple nutrients have been clinically shown to favorably alter good cholesterol levels including: vitamins C, E, B6, B12, niacin, folic acid, magnesium and selenium, with protein-building amino acids, powerful antioxidants such as Coenzyme Q10, alpha lipoic acid, N-acetyle cysteine, and policosanol, and extracts of hawthorn, garlic, grape seed, and soy isoflavones. Although this HDL-boosting combination does not result in a significant reduction in LDL, antioxidants found in this formulation can help stabilize LDL and prevent build up in the arterial wall.

This formula combines essential vitamins and minerals, at levels recommended by the American Heart Association. It contains amino acids, antioxidants, and botanicals that have all been used safely for years. No serious adverse effects have been found following supplementation and the combination is safe to use with statin drugs.

Plant sterols, found in nuts, vegetable oils, corn, and rice are structurally similar to cholesterol and are able to block its absorption. Each day the liver receives about 800 mg of cholesterol from intestinal absorption through receptor sites. After entering these channels, the cholesterol is absorbed into the bloodstream. Since plant sterols look similar to cholesterol, they fit perfectly into these receptor sites and block the absorption, which allows the cholesterol to remain in our intestines where it can eventually be excreted. A large amount of plant sterols reduces the amount of cholesterol transported from the intestinal tract to the liver. This cholesterol reduction causes a decrease in LDL levels.

Even if a person does not have high cholesterol levels, reducing bad and raising good cholesterol greatly reduces their risk for ever developing chronic heart disease. Due to side effects, physicians do not normally prescribe statin drugs to people without actual heart disease of high LDL cholesterol levels. Instead, they recommend dietary changes. The HDL-boosting combination and LDL-lowering pantethine and plant sterols blend can effectively help people with heart disease, uncontrolled cholesterol levels, high triglyceride levels, or people who just want to improve their heart health.



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HDL Booster - Boost your good cholesterol
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Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

 

                                      

 

 

HDL BOOSTER

(Product No. 02922)

 

 

 

DESCRIPTION:

 

HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*  

 

HDL Booster:

 

·         Formulated by Dr. Dennis Goodman, Chief of Cardiology at Scripps Memorial Hospital

·         Clinically studied to increase good cholesterol levels up to 23%*1

·         All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association

·         Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2

 

STRUCTURE/FUNCTION:

 

HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*  

 

FORMULA:

 

Two tablets (one serving) contain:

 

Vitamin C (ascorbic acid)                                                          148 mg

Vitamin E (as natural mixed tocopherols)                                    35 IU

Niacin (as niacinamide)                                                              21 mg

Vitamin B6 (as pyridoxine HCl)                                                  3 mg

Folic Acid                                                                                 301 mcg

Vitamin B12 (as cyanocobalamin)                                              20 mcg

Magnesium (from magnesium amino acid chelate)                       10 mg

Selenium (as L-selenomethionine)                                               49 mcg

Proprietary Blend                                                                      388 mg

   hawthorn (Crategus oxyacantha) berry extract,         

   taurine, garlic (Allium sativum) bulb, grape seed (Vitis

   vinifera) extract, grape skin (Vitis vinifera) extract,

   N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine

   max) isoflavones, tocotrienols

L-Arginine (as L-arginine HCl)                                                  153 mg

L-Carnitine (as L-carnitine L-tartrate)                                        51 mg

Coenzyme Q10 (CoQ10)(ubiquinone 10)                         25 mg

Policosanol                                                                                7 mg

 

Other ingredients: See label for most current information.

 

Contains no: sugar, salt, yeast, wheat, gluten,  corn, dairy products, artificial coloring, artificial flavoring, or preservatives.  This product contains natural ingredients; color variations are normal. 

 

INTRODUCTION:

 

Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5

 

Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4

 

Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4

 

Types of Cholesterol

 

Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5

 

LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6

 

Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7

 

The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7  

 

HOW IT WORKS:

 

HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9

 

Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at Scripps Memorial Hospital to evaluate the effects of a proprietary supplement on lipid profiles. The dietary supplement, which mirrors HDL Booster and contains a combination of antioxidants, B-vitamins, amino acids, and botanical extracts, was developed by Dr. Goodman, the leading cardiologist at Scripps. The trial involved 50 people, who were evaluated prior to the study, then again at three and six months. After three months of supplementation, good cholesterol levels increased in all groups.* The changes were more pronounced at the six-month time point, where good cholesterol rose up to 23 percent and levels of HDL-2 (the best cholesterol) increased 50 percent in one subset of participants (HDL <40 mg/dL).*1 Additionally, the supplement also helped maintain healthy triglycerides levels that were already within the normal ranges.* Decreases in homocysteine, an amino acid found in the blood that plays a role in cardiovascular health, were observed as well.*1,10

 

The following chart summarizes the benefits of each of the ingredients in HDL Booster:

 

Ingredient

Benefit

Vitamin C

An antioxidant clinically shown to support the health of the cardiovascular system and increase HDL-2 cholesterol levels.*11,12 An important factor in many metabolic reactions, including the conversion of cholesterol to bile salts and the formation of healthy connective tissue. Vitamin C provides protection for the inner lining of the arteries.*13,14

Vitamin E

Another powerful antioxidant, which inhibits the oxidation of low density lipids by inactivating free radicals.* Thought to inhibit the breakdown of certain fatty acids that help form cell structures, especially membranes13

Also supports healthy cholesterol levels already within the normal range.*15,16

Niacin

In lipid metabolism, supports normal cholesterol production and metabolism to help retain healthy cholesterol levels that are already within normal limits.*13 Increases good cholesterol levels, particularly HDL-2 (the best cholesterol).*17 Through peripheral vasodilatation, niacin also supports the retention of healthy blood pressure that is already within the normal range.*13

Vitamin B6

An essential coenzyme for normal amino acid metabolism. In particular, vitamin B6 is necessary for the breakdown of homocysteine, an amino acid that plays a supporting role in cardiovascular health.* Also involved in the production of circulating antibodies.13 High levels of circulating vitamin B6 have been associated with reduced levels of C-reactive protein, another important indicator of heart health.*18

Folic Acid        

Another homocysteine lowering agent, folic acid is essential for the formation of red and white blood cells and involved in the synthesis of certain amino acids.*13

Vitamin B12

A ubiquitous coenzyme necessary for DNA synthesis. Also lowers homocysteine levels.*13

Magnesium

Increases HDL levels, supporting a healthy lipid profile, and helps maintain healthy blood pressure already within the normal limits.*19 Magnesium is a constituent of many coenzymes and is required for normal functioning of muscle and nervous tissue.20

Selenium

An essential trace mineral with powerful antioxidant capabilities.*20 Research has revealed that selenium supports cardiovascular function.*21

L-Arginine

An important amino acid and precursor to nitric oxide (NO), which is important for the health of the cardiovascular, immune, and nervous systems.*22 In clinical study, an L-arginine-enriched diet increased good cholesterol levels.*23

L-Carnitine      

A naturally occurring hydrophilic amino acid derivative, both produced in the kidneys and liver and derived from dietary sources. Along with Coenzyme Q10, L-carnitine is a key factor in metabolism, supporting the production of cellular energy.*24 Also shown to increase good cholesterol (HDL) levels.*25 L-carnitine supports healthy blood flow.*26

Coenzyme Q10 (CoQ10)

A fat-soluble nutrient present in the mitochondria of virtually all cells, CoQ10 is an essential factor for cellular energy production.27 Also a powerful free radical scavenger, clinically shown support arterial health.*27,28

Supplementation significantly improves good cholesterol levels.*29 Additionally, CoQ10 supports healthy heart contractility and circulation.*

Policosanol

A unique mixture of essential alcohols, including octacosanol, tetracosanol, hexacosanol and triacontanol, derived from sugar cane.30 In a clinical study, supplementation resulted in a 14 percent increase in HDL cholesterol over an 8-week period.*31

Hawthorn Berry Extract

Helps retain healthy cholesterol levels already within the normal range.* Supports the muscle strength of the heart, helping to maintain healthy heart rhythm, contractility, and vascular circulation.*32 A source of antioxidant constituents that protect against oxidative damage.* Supports the health of veins and arteries.*33,34 Also helps maintain healthy blood pressure levels already within the normal ranges.*

Taurine

An essential amino acid, present in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. Possesses both antioxidant and membrane-supportive properties.*35 Helps maintain a healthy lipid profile by increasing good (HDL) cholesterol levels.*36,37

Garlic Bulb

A powerful antioxidant that possesses wide-ranging cardiovascular health benefits.*38 Clinically shown to increase good cholesterol levels, particularly HDL-2 cholesterol.* 39

Grape Seed Extract

A source of free-radical scavenging phytonutrients, known as polyphenols.* Promotes healthy circulation.* Also supports cardiovascular health by increasing HDL cholesterol levels*40,41

N-Acetyl-L-Cysteine (NAC)

A derivative of the amino acid, cysteine, NAC is a key intermediary in the conversion of cysteine into glutathione, one of the body’s primary cellular antioxidants.* Supports the health of the cardiovascular and immune systems.* Also shown to significantly increase in HDL cholesterol.*42

Alpha Lipoic Acid (ALA)

An antioxidant and vital cofactor necessary for the production of cellular energy, ALA helps recycle other important antioxidants, including vitamins C and E, CoQ10, and glutathione. Also helps maintain healthy blood flow and healthy heart contraction.*43

Soy Isoflavones

Provide antioxidant protection, supporting cardiovascular and immune system health.* Soy protein-enriched diet has been shown

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High Absorption CoQ10
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Date: February 13, 2006 05:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: High Absorption CoQ10

The human heart beats more than two and a half billion times in an average lifetime. The energy required for this miracle of nature is enormous, and maintaining heart tissue energy levels is essential. A vitamin-like nutrient found in the human body, Coenzyme Q10 or CoQ10 supports heart function. Without adequate CoQ10, cells become energy-deficient. When nourished with optimal levels of CoQ10, your body tissues, including the liver, nerves and muscles function optimally. With its high energy requirements, the heart needs to be supplied with CoQ10 at all times. Numerous clinical studies have shown significant improvements in heart function with oral administration of CoQ10. Immune cells need large amounts of energy, and CoQ10 helps make it available. A versatile antioxidant, it stabilizes membranes and protects them from free-radical damage. A fat-soluble nutrient, CoQ10 is difficult to absorb, so we’ve added Bioperine. Preliminary Trails on humans have shown significant increases in absorption of Bioperine-enhanced nutrients. High absorption CoQ10, a pharmaceutical grade supplement, is now available in three different forms: 30mg/60 caps; 100mg/30 caps; and 100mg/60 caps. High Absorption CoQ10 with bioperine


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The Free Radical Theory
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Date: December 14, 2005 12:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Free Radical Theory

The popular theory has been the subject of a great deal of research. Developed by Denham Harman, M.D., Ph.D., at the University of Nebraska in 1956, the free radical theory proposes that unstable molecules known as free radicals are responsible for inflicting extensive cellular damage, which causes cell death and dysfunction and eventually, disease. The most common type of free radicals are oxygen derived, and free radical damage is often referred to as oxidation.

Environmental sources of free radicals include radiation (I.E., sun exposure, X-rays), ozone and nitrous oxide, heavy metals (i.e., mercury, cadmium, lead), smoke, alcohol, saturated fat, and other chemicals and pollutants. The body itself generates free radicals in performing essential bodily functions including energy production and immune activities. Fortunately, the body also has the ability to create antioxidants to neutralize the free radicals and prevent extensive cellular damage. When free radicals are not neutralized by antioxidants, they inflict large-scale cellular damage which can cascade and lead to age-related degenerative diseases such as osteoarthritis, osteoporosis and age –relaged macular degeneration. For example, free radical damage to joint cells may cause the cartilage to become rough or break down, and can lead to the development of osteoarthritis. Antioxidants are needed to comb at free radicals and prevent this cellular damage. “Oxidative stress can lead to DNA mutations, cell death, and disease, all of which contribute to aging,” said Gerald R. Cysewski, president and chief executive officer (CEO) at Cyanotech corp. “Antioxidants are produced naturally by the body to combat oxidative stress by neutralizing free radicals. Increasing the amount of antioxidants in one’s system by consumption of supplements can provide further protection from the damaging effects of free radicals.”

Because the body is continually assaulted by free radicals, antioxidant supplementation is often necessary. “by taking certain nutrients that our bodies stop producing over time, supplements help us to maintain a youthful look and health, which in turn enhances the quality of life,” Alkayali said. “Furthermore, supplements can help decrease oxidative stress that may otherwise accompany age-related illness and disease.”

Many Substances are known antioxidants including certain enzymes, vitamins, phytochemicals and minerals, and include Vitamin C, Vitamin E, alpha-lipoic acid, Coenzyme Q10 (CoQ10), Carotenoids, Selenium, superoxide dismutase, melatonin, quercetin, catechins, and zinc.

Consuming a diet high in plant sources of powerful antioxidants is an important step to deter ageing, because nutrients from foods are often highly bioavailable and can act synergistically to increase their health benefits. Garlic contains several antioxidant phytochemicals and minerals including allicin, beta-carotene, quercetin, selenium and zinc, and may have a protective effect against stomach and colorectal cancers.

Catechins are potent antioxidants flavonoids, with the best known source being green tea; they include gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC) and epigallocatechin gallate (EGCG). These antioxidants are being studied for their powerful abilities to combat free radical damage. In particular, EGCG has been researched for its reported protection against certain cancers and Alzheimer’s disease.

Green Foods such as seaweed, sea vegetables, young grain grasses and shoots, broccoli, cabbage and other green leafy vegetables pack a nutritional punch due to their concentratged amounts of antioxidant carotenoids, vitamins and the enzyme superoxide dismutase (SOD). SOD is produced by the body and neutralizes free radicals known as superoxide radicals, which cause damaging fat oxidation. GliSODin is a patented form of SOD derived from cantaloupe and bound to a wheat protein for superior bioavailability. “GliSODin promotes the body’s production of its own endogenous antioxidants, including SOD, catalase and glutathione peroxidase, in virtually every cell,” said Eric Anderson, brand manager at P.L. Thomas. “This activation of the cellular antioxidant defenses across the whole body creates a state of alertness against any shock of oxidative stress, including sun rays, to which our body may be exposed.”

Pomegranates contain two powerful antioxidants—ellagic acid, derived from fruit’s seeds, and punicaligans, found in the juice. “Research has shown that the juice from the pomegranate, rich in polyphenols, reduces oxidative stress by helping to produce enzymes to fight free radicals,” Alkayali said. NeoCell Corp. manufactures of ellagic-acid based Pomegranate Power, while P.L. Thomas supplies POM40p, a kosher-free pomegranate juice extract standardized to 40-precent punicocides, polyphenols belong to the punicalagin family.

Consumer demand is on the rise for products that address degenerative health conditions, including supplements that support function of the bones, joints, eyes. According to a June 2005 report by the freedonia group, “Bone and joint care products will continue to dominate the health maintenance segment, spurred by a growing customer base and a plethora of new and improved products expected to soon enter the marketplace.” The report also projected rapid gains for vision care. “Demand for vision care products will be propelled by aging baby boomers who are becoming aware of debilitating eye conditions and seeking both preventive measures and ameliorative treatments.” Dietary Supplements can help prevent and ease symptoms of age-related diseases affecting the joints, bones and eyes, including osteoarthritis, osteoporosis and age-related macular degeneration (AMD).



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Coenzyme Q10 and Cardiovascular Health.
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Date: December 13, 2005 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coenzyme Q10 and Cardiovascular Health.

CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!

CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.

CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.

As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”

“The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.

Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.



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Put a spring in your step with these energizing tips
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Date: August 02, 2005 10:03 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Put a spring in your step with these energizing tips

Put a spring in your step with these energizing tips

Stress, illness and even our everyday routines can all affect our energy levels and our ability to do daily tasks. Perpetual fatigue not only keeps us from doing what we would like to do but also what we have to do. Below are some tips for easy ways to boost your energy and increase your enjoyment of life: FIGHT AND WIN THE Allergy WAR

DECREASE YOUR INTAKE of white flour and sugar, processed foods, red meat and fatty foods. Increase your intake of fresh fruits and vegetables, whole grains and soy products.

ENERGY LEVELS CAN be affected by digestive problems, such as sluggish bowel. Try a juice fast followed by a diet of whole, raw foods to help cleanse your body and recharge your immunity.

INSTEAD OF RELYING ON caffeinated soft drinks to get you through the day, try an iced ginseng or peppermint herbal tea. Ginseng is a particularly energizing herb that is good with honey.

FATIGUE CAN ALSO BE a result of a vitamin deficiency. B vitamins in particular are important for our energy levels and our ability to handle stress. Consider getting a B12 shot.

IF YOU ALWAYS feel tired and rarely sleep well, consider taking L-tryptophan supplements. With the right dosage, you should feel a big difference in your anxiety levels and how rested you feel.

IF YOU ARE SUFFERING from hidden food allergies, you are overworking your immune system. This situation can cause fatigue. Keep a food diary to help you eliminate the guilty foods.

CONSIDER A FISH, flaxseed or evening primrose oil supplement for omega-3 and omega-6 fatty acids. The typical American diet is deficient in essential fatty acids, which affect every body system.

Get energized—try these natural energy-enhancing tips

PHYSICAL INACTIVITY or sleeping too much can also lead to a general lack of energy. Even if a gym is not for you, walking or stretching for 45 minutes, three times a week is suggested.

SOMETIMES FATIGUE IS DUE to a problem with the thyroid gland, especially if you are pregnant. Consider talking to your health-care professional about thyroid testing. Adding kelp to your diet is also helpful because of its iodine content—an iodine deficiency is sometimes responsible for thyroid disorders.

DEPRESSION, NERVOUS TENSION AND emotional or physical stress can tax the body, and if experienced daily, they can lead to a chronic lack of energy. Research suggests that daily journal writing is effective for dealing with depression and stress. Daily meditation is also helpful.

MAKE AN HERBAL JUICE by mixing sage, rosemary and oat juice (from the green plant), and take 1 tablespoon each day. This juice will help counteract nervous tension and irritability, as well as exhaustion. It is also good for insomnia if taken before bed.

Coenzyme Q10 IS A useful supplement that increases the supply of oxygen to your body tissues, thereby boosting your energy and performance levels. This supplement should be easy to find at any pharmacy or health store.

LONG-TERM FATIGUE can be a symptom of low blood pressure, arthritis, diabetes, cancer or liver problems. If you are concerned, see your health care professional.

CONSIDER GETTING TESTED FOR weak adrenals or low iron in the blood. If you are suffering from either of these problems, you are likely to feel a general lack of energy. DHEA, a precursor hormone, can help with adrenal problems, and low iron can be remedied with a simple mineral supplement fortified with iron.

MAKE AN EFFORT to unwind before bedtime. By reading, going for a short walk or taking a bath before you go to sleep, you have a chance to release tension and stress that will affect how well you sleep each night. Also, try not to eat right before retiring to bed.

CONSIDER ADDING TWO OR MORE yoga positions to your daily routine. There are a number of books on how yoga increases well-being and fights fatigue.

THE PRESENCE OF A yeast infection in the body can also decrease energy levels by overtaxing the immune system. These infections can be brought on by antibiotics, birth control and environmental stress. Acidophilus and a cleansing diet are helpful for dealing with yeast infections. Serious infections may require medication.

THE PRESENCE OF PARASITES in the body can also compromise your immune system and lead to chronic fatigue or lack of energy. Goldenseal, echinacea, grapefruit seed extract, zinc and vitamin C can all help fight microbes and support healthy immune function.

ESPECIALLY DURING THE spring and summer months, when the weather is getting warmer, you should be drinking plenty of water. Also, consider trying this energy booster: 3 cups pineapple juice, 1 cup water, 1 cup alfalfa sprouts and 10 almonds, all blended until smooth.

ONE OF THE MOST substantial problems of the typical American diet is a lack of fiber. Aim for 25–35 grams of dietary fiber each day by including beans, fruits (like apples, skin included) and whole grains to the diet. Fiber is essential for proper digestion and elimination, both of which affect all other body systems.

BOOSTING THE IMMUNE SYSTEM is especially important for enhancing your energy levels, especially if you have been ill. Consider adding vitamin C, bee products and green foods to your daily diet to fight infection and fatigue.



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Natural Health for a Healthy Heart
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Date: July 13, 2005 09:17 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Health for a Healthy Heart

Natural Health for a Healthy Heart

Cardiovascular disease is on the rise. Heart disease, stroke, and related disorders kill more Americans than any other ailments combined. In 1990 approximately one million Americans died form cardiovascular disease. Arteriosclerosis (hardening of the arteries) is the leading cause of heart attacks and strokes. Fat and cholesterol accumulate around the heart and inner walls of the arteries. This causes blood flow to slow and blood pressure to rise. Blood clotting is also a problem when the arteries are clogged which, if a clot breaks loose, can cause strokes or heart attacks according to where they end up. Heart disease is usually advanced before a problem arises. Prevention should be the first goal.

Heart disease is much less common in “primitive” societies. This is due in part to the lifestyle and diet choices of Americans. Diet is viewed as the most important factor in heart related disorders. An increased intake of sugar, refined flour and simple carbohydrates may also be contributing factors. Other risk factors include a family history of heart disease, cigarette smoking, high blood pressure, type A personality, stress, diabetes, obesity, high blood cholesterol levels, physical inactivity and coronary artery disease. Changes must be made in diet and life-style in order to prevent heart disease.

DIET

Following a diet low in animal fat and refined sugars but high in fiber is highly recommended. Whole grains, almonds, fresh fruits and vegetables, a variety of legumes, skinless turkey, chicken and fish should be the main dietary elements. Brown rice, garlic, onions, olive oil, raw fruits and vegetables, sprouts, asparagus, apples, bananas, beans, buckwheat, seeds, whey powder, and yogurt are especially good for the heart. Avoid caffeine, alcohol, red meat, refined carbohydrates, and white flour. Limit intake of dairy products which contain high amounts of fat. Homogenized dairy products contain an enzyme called xanthine oxidase which is believed to cause artery damage and could lead to arteriosclerosis. Use olive oil and canola oil when using fat. Avoid palm oil, coconut oil, peanut oil and cottonseed oil.

SUPPLEMENTS

Choline, inositol and lecithin: These act as fat emulsifiers in the bloodstream and can help prevent plaque buildup.

Chromium: Chromium is known for recent studies linking it to a reduced risk of heart disease. It may help prevent plaque buildup in the arteries. Low levels of chromium are thought to be a risk factor for developing heart disease. It also may help increase the beneficial HDL cholesterol and aid in lowering the LDL cholesterol.

Coenzyme Q10: This can help oxygenate the heart muscle helping to prevent additional heart damage. Coenzyme Q10 can help the body break down fatty acids converting them to energy. This is often lacking in individuals with heart problems. Essential Fatty Acids: These can help prevent hardening of the arteries by preventing the blood cells from clumping together and forming clots. They also help with the assimilation of fat soluble vitamins.

Germanium: Germanium has been found to lower high blood pressure and improve circulation in the body. Calcium and Magnesium: Both of these minerals contribute to the muscular contraction and relaxation of the heart. They are essential for the proper function of the heart muscle and maintaining normal heart rhythm and blood pressure. Low levels of calcium have been linked to high blood pressure.

L-Carnitine: This is an amino acid that can help the heart by reducing fat levels in the blood. Vitamin C with bioflavonoids: Vitamin C helps prevent blood clots and strengthens the capillary and blood vessel walls. It may help prevent high blood pressure, arteriosclerosis, lower cholesterol, repair arterial walls, and contribute to reversing heart disease.

Vitamin E: Vitamin E is well known for its beneficial effect on the heart. Selenium: Low levels of selenium have been associated with heart disease.

HERBS

Hawthorn: This herb is great for cardiovascular health. Garlic: Garlic is one of the most studied herbs for cardiovascular health. Several recent studies link garlic to lower incidence of cardiovascular disease.

Cayenne: This is also known as capsicum and is beneficial on circulation and cleaning and nourishing the blood vessels.

Ginkgo: Ginkgo relaxes the blood vessels and improves the flow of blood even in constricted arteries. Rosemary Tea: This is a traditional heart tonic that helps to promote circulation and lower blood pressure. Chinese Mushroom (auricularia polytricha): This is a natural blood thinner.

EXERCISE:

It is important to include exercise in the daily routine. Aerobic exercise is known to help improve the heart1s pumping ability, reduce serum cholesterol levels, decrease the risk of heart disease, and reduce the risk of high blood pressure as well as many other ailments. Exercising an average of three to five days a week for thirty minutes will benefit the body. Actually any amount of exercise is beneficial for the body, so try and do something each day.

REDUCE STRESS:

Include relaxation techniques to reduce stress. Stress can increase the risk of heart disease. Stress releases adrenaline which causes the heart to work harder. If you feel resentment, fear or anger, find ways to deal with these in a positive way. Pursuit serenity and peace in life. Exercise, self hypnosis, biofeedback, meditation, yoga and prayer can all help develop inner peace.

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New* Improved formula - Cholest-Response Lower Cholesterol
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Date: July 08, 2005 09:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: New* Improved formula - Cholest-Response Lower Cholesterol

New & Improved Formula!

Cholest-Response™

  • ? Now with Sytrinol™, gamma E, policosanol, L-arginine, and selenium.
  • ? A Cholesterol Rescue™ product: helps maintain cholesterol levels already in the normal range.
  • ? Bio-Aligned Formula™: supports multiple body systems including the heart, blood vessels, nervous system, thyroid, liver and gastrointestinal tract.

    Serving Size:

    4 tablets contain:
    Vitamin C (as ascorbic acid) 600 mg
    Vitamin E 16 IU
    (from gamma-vitamin E complex)
    Niacin (as inositol hexanicotinate) 500 mg
    Iodine (from kelp) 150 mcg
    Selenium (as L-selenomethionine [SelenoPure™] & sodium selenite) 100 mcg
    Chromium (as chromium polynicotinate [ChromeMate®] & chromium picolinate) 100 mcg
    Phytosterol Complex 40% 750 mg
    Yielding 300 mg beta-sitosterol
    Garlic Powder Extract 600 mg
    (standardized to 8,000 ppm allicin)
    Turmeric Extract 526 mg
    Yielding 500 mg curcumin
    gamma-Vitamin E Complex 500 mg
    Inositol 350 mg
    (as inositol and inositol hexanicotinate)
    Red Yeast Rice 350 mg
    Yielding 1.5% mevinolinic acid monacolins
    Artichoke Extract 250 mg
    (standardized to 2.5% cynarins)
    L-Arginine (as L-arginine HCl) 240 mg
    Methylmethioninesulfonium Chloride 200 mg
    (vitamin U)
    Green Tea Extract 105 mg
    Yielding 100 mg polyphenols, 36 mg EGCG
    Sytrinol™ 100 mg
    (proprietary blend of citrus polymethoxylated
    flavones and palm tocotrienols)
    Soy Bean Concentrate 100 mg
    Yielding 40 mg total isoflavones
    Ginkgo Leaf 24% (50:1 Extract) 60 mg
    Guggul Extract (10% guggulsterones) 50 mg
    Dandelion Root Extract (4:1) 50 mg
    Hawthorne Berry Extract (4:1) 50 mg
    Myricetin 30 mg
    Policosanol 10 mg
    Coenzyme Q10 5 mg

    Suggested Use: Take 4 tablets each night or as recommended by your health care professional.

    CodeSize Retail UPC Code
    SN127130 tabs $12.50021078012719
    SN127260 tabs $23.50021078012726
    SN1880120 tabs $44.98021078018803

    We offer Source Naturals at 46% OFF Man. Suggested Retail



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    NEW PRODUCT ANNOUNCEMENT
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    Date: July 05, 2005 06:29 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: NEW PRODUCT ANNOUNCEMENT

    RENEWAL ANTIOXIDANTS

    The Most Comprehensive Antioxidant Formula Available!

  • Bio-Aligned FormulaTM that provides both water and fat-soluble antioxidants to support the heart and blood vessels, liver, skin, vision, the immune system, energy production and
  • Helps protect the body against free radicals including peroxyl, hydroxyl, and superoxide radicals as well as singlet oxygen.
  • Some scientific evidence suggests consumption of antioxidant vitamins may reduce the risk of certain forms of cancer. However, the FDA has determined that this evidence is limited and not conclusive.

    Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
    Vitamin C (as ascorbic acid & ascorbyl palmitate) 1,000 mg
    Vitamin E (as d-alpha tocopheryl) 400 IU
    Riboflavin (vitamin B-2) 25 mg
    Zinc (as monomethionine [OptiZinc®]) 15 mg
    Selenium (as L-selenomethionine [SelenoPure™] 200 mcg
    & sodium selenite)
    Manganese (as manganese succinate) 10 mg

    gamma-Vitamin E Complex 500 mg
    Turmeric Rhizome Extract 95% 300 mg
    alpha-Lipoic Acid & 210 mg
    R-Lipoic Acid
    N-Acetyl Cysteine 200 mg
    Wheat Sprouts 150 mg

    Quercetin 100 mg
    Amla Fruit (Phyllanthus emblica) 100 mg
    Grape Seed Extract 100 mg
    (Proanthodyn™)
    Green Tea Extract 100 mg
    (95% polyphenols, 35% EGCG) Hawthorn Berry Extract (4:1) 100 mg
    Mega H- Microcluster™ 100 mg
    Silica Hydride Powder
    Rosemary Leaf Extract 100 mg
    (20% diterpenes)
    Ginger Root 100 mg
    Ginger Root Ext. (5% gingerols) 80 mg
    SOD 80 mg (superoxide dismutase [GliSODin®])
    Milk Thistle Seed Extract 80 mg
    Yielding 66 mg Silymarin
    Pomegranate Seed Extract 60 mg
    (40% elagitannins)
    Pomegranate Seed Extract 60 mg
    (40% elagitannins) Red Raspberry Leaf Extract 50 mg
    (40% elagitannins)
    Blueberry Leaf Extract 50 mg
    (20% chlorogenic acid)
    L-Carnosine 50 mg
    Ginkgo Biloba Leaf 24% 40 mg
    (50:1 Extract)
    Coenzyme Q10 30 mg
    L-Glutathione 25 mg
    Total Resveratrols (from 20 mg
    Polygonum cuspidatum Extract)
    Bilberry Fruit 20 mg
    Std. Ext. (37% anthocyanosides)
    Tocotrienol Complex 20 mg
    (Tocomax®)
    Myricetin 20 mg
    DMAE (as bitartrate) 20 mg
    Lycopene 3 mg
    Lutein (FloraGLO®) 3 mg
    Astaxanthin 1 mg



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    Life Force - The Energy Activator
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    Date: June 29, 2005 10:35 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Life Force - The Energy Activator

    Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%

    We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.

    Bio-Align™ Yourself with Life Force

    LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.

    Get Ahead with Activated Energy and a Healthy Metabolism

    Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains Coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.

    LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.

    Protect Your Heart and Circulatory System

    The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.

    Skin and Musculoskeletal Support

    LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.

    Brain and Nerves Nutrition

    The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.

    Immune Defense

    LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.

    Powerful Liver Support

    Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as Coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.

    Complete Antioxidant Defense

    Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.

    Cutting-Edge Vision Nutrition

    The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.

    Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle

    LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.

    Support Healthy Fat and Protein Consumption with Life Force

    Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.

    Complete Energizing Nutrition

    LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!

    References
    Guyton, A. 1991. Textbook of Medical Physiology, Eighth Ed. W.B. Saunders Co., Philadelphia, PA. Halliwell, B. and Gutteridge, J. 1995. Free Radicals in Biology and Medicine. Clarendon Press, Oxford. Linder, M. 1991. Nutritional Biochemistry and Metabolism, Second Ed. Appleton and Lange, Norwalk, CT. Mathews, C. and van Holde, K.E. 1990. Biochemistry. The Benjamin Cummings Publishing Co., Inc. Shils, M. and Young, V. 1980. Modern Nutrition in Health and Disease, Sixth Ed. Lea & Febiger, Philadelphia, PA.



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    SPECIFIC ACTIONS ASSOCIATED WITH GARLIC
    TopPreviousNext

    Date: June 25, 2005 10:34 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: SPECIFIC ACTIONS ASSOCIATED WITH GARLIC

    SPECIFIC ACTIONS ASSOCIATED WITH GARLIC

  • • Antioxidant: Protects cells against damage by free radicals found in environmental pollutants including heavy metals. Garlic contains the highest level of the antioxidant selenium, which affords excellent cellular protection.
  • • Anti-toxic: Can be considered a radiation antidote in that it stimulates cellular detoxification.
  • • Anti-cancer: Blocks the ability of carcinogens to mutate healthy cells into malignant ones. In some cases, Garlic can even inhibit the early proliferation of cancerous cells.
  • • Decongestant: Helps to rid the respiratory tract of mucus.
  • • Artery Cleanser: Significantly lowers blood levels of triglycerides which have been associated with an increased risk of heart attack.
  • • Anti-artherosclerotic: Promotes the regression of fatty deposits in blood vessels, a major cause of atherosclerosis, and can even help reverse arterial blockages caused by the collection of plaque.
  • • Antibiotic: Works as an immune system stimulant which helps the body fight bacterial, viral and fungal infections. Enhancing immune defenses may also help the body rid itself of cancerous invaders.
  • • Anticoagulant: Reduces the tendency of the blood to clot and helps to dissolve existing clots. Both of these actions are very significant in reducing the risk of heart attack and stroke.
  • • Tonic: Garlic has a positive effect on the heart, stomach, lungs and spleen.
  • • Anti-infection: Externally, garlic can be used as a drawing poultice.
  • • Antiparasitic: Garlic has traditionally been used in enemas to rid the colon of intestinal parasites.
  • • Blood Purifier: Helps to stimulate the lymphatic system to more efficiently get rid of waste material.
  • • Glucose Control: Garlic has been found to be useful in controlling glucose tolerance and is beneficial for both hypo and hyperglycemia. Anyone with diabetes can benefit from garlic as well.
  • • Swelling: Garlic suppositories have been used to shrink hemorrhoids.
  • • Anti-inflammatory: The anti-inflammatory action of garlic makes it a valuable treatment for arthritis. Garlic reduces joint swelling and inflammation
  • • Antihypertensive: Garlic has been recognized by the Japanese Food and Drug Administration as an official treatment for high blood pressure.
  • • Garlic is a “wonder” food that is considered to be one of the most effective natural healing substances in the world.

    COMBINATIONS THAT ENHANCE GARLIC

  • • garlic, capsicum and vitamin C
  • • garlic, Coenzyme Q10, carnitine, selenium and hawthorne berries
  • • garlic, ginseng, echinacea, and white willow
  • • garlic, horehound, echinacea, chickweed, mullein and licorice
  • • garlic, onion, raspberry leaves and licorice

    Garlic: Primary Applications

  • • asthma
  • • artherosclerosis
  • • arthritis
  • • blood clots
  • • blood pressure
  • • bronchitis
  • • Candida Albicans
  • • cardiovascular disease
  • • cancer prevention
  • • circulation
  • • colds
  • • colitis
  • • contagious diseases
  • • coughs
  • • ear infections
  • • digestion
  • • fever
  • • flu
  • • fungus
  • • gas
  • • heart disease
  • • hypertension
  • • infections (viral, bacterial and fungal)
  • • liver disorders
  • • parasites
  • • prostate gland
  • • respiratory diseases
  • • staph and strep infections
  • • yeast infections

    Garlic: Secondary Applications

  • • acne
  • • allergies
  • • arthritis
  • • diabetes
  • • diarrhea
  • • emphysema
  • • gallbladder
  • • hypoglycemia
  • • insomnia
  • • kidneys
  • • pneumonia
  • • rheumatism
  • • sinus
  • • ulcers
  • • warts
  • • worms

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    RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
    TopPreviousNext

    Date: June 24, 2005 05:34 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available

    The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.

    Bio-Aligned Antioxidant Support

    RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.

    Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.

    Healthy Heart

    Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.

    Nourishing the Brain

    Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.

    Liver Support

    Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.

    Immune Defense

    The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.

    Skin & Connective Tissue

    Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.

    Clear Vision

    Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.

    Energy Generation

    Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.

    DNA Protection

    DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.

    Living Longer, Living Better Strategies for Wellness

  • • Eat Well: Include plenty of fresh fruits and vegetables. Antioxidants in foods exist as vitamins C and E, beta-carotene, selenium and as flavonoids (tea), lycopene (tomatoes) and anthocyanins (berries). The highest concentrations of antioxidants are found in deeply colored fruits and vegetables such as dark leafy greens, artichokes, blueberries, cranberries, plums, blackberries and cherries. Spicing up food with cinnamon, turmeric, cloves and oregano can also boost antioxidant power.
  • • Stay Active: Exercise benefits the heart, helps regulate weight and slows the aging process by increasing the amount of oxygen available to body tissues.
  • • Reduce Stress: Deep breathing improves your blood’s oxygenation and circulation.
  • • Stop Smoking: Smoking depletes the body of vitamins C and E along with other antioxidants.

    Wellness Revolution

    Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.

    References

    Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.

    Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf

    Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein

    Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts

    Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric

    Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE

    Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc

    Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf



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    REFERENCES
    TopPreviousNext

    Date: June 22, 2005 09:57 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: REFERENCES

    REFERENCES


    1. Interview with Dr. Michael Pariza, July 3, 1997.
    2. “Effects of Temperature and Time on Mutagen Formation in Pan-Fried Hamburger,” by M. Pariza, Samy Ashoor, Fun Chu and Daryl Lund, March 10, 1979, Cancer Letters, 7 (1979) 63-69.
    3. “Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid,” Y.L Ha, N.K. Grimm and M.W. Pariza, August 25, 1987. IRL Press limited, Oxford, England.
    4. Interview with Dr. Mark Cook, July 3, 1997.
    5. “Conjugated Linoleic Acid in Cancer Prevention Research: A Report of Current Status and Issues,” A special report prepared for the National Live Stock and Meat Board, Ip, Clement, Ph.D., May 1994. See also “Conjugated linoleic acid, a newly recognised nutrient” in the June 17, 1997, issue of Chemistry and Industry by M. Pariza, pp. 464-466.
    6. Op.Cit. Pariza, Chemistry and Industry.
    7. Op. Cit. Ip, National Live Stock and Meat Board. See also, “Conjugated Linoleic Acid (9,11 and 10,12-Octadecadienoic Acid) is Produced in Conventional by Not Germ-Free Rats Fed Linleic Acid,” Sou F. Chin, Et. Al, Dec. 16, 1993, Journal of Nutrition 124: 694-701 1994.
    8. Ibid.
    9. Interview with Cook. 10. Op. Cit. Ip, National Live Stock and Meat Board.
    11. Ibid.
    12. Op. Cit., interview with Pariza., and “Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid,” Y.L. Ha, N.K. Grimm and M.W. Pariza, Aug. 25, 1987, IRL Press Limited, Oxford England.
    13. “Conjugated linoleic acid: An anticarcinogenic fatty acid present in mile fat,” by Peter Parodi, Australian Journal of DairyTechnology. Nov. 1994, 49 p. 93-94.
    14. The Washington Post “Now We’re a Nation of Lite Heavyweights,” Sept. 1, 1994, Sec. B. P. 10.
    15. “A beef-derived mutagenesis modulator inhibits initiation of mouse epidermal tumors by 7, 12 dimethylbens[a]anthracene,” by M. Pariza and W. Hargraves, Jan. 2, 1985, Carcinogenesis, vol 6., no. 4 pp. 591-593, 1985, IRL Press, Limited, Oxford, England.
    16. Op. Cit. Pariza, Chemistry and Industry.
    17. “Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid,” Y.L. Ha, N.K. Grimm and M.W. Pariza, Aug. 25, 1987, IRL Press Limited, Oxford England.
    18. “Mammary Cancer Prevention by Conjugated Dienoic Derivative of Linoleic Acid,” Clement Ip, Sou Fe Chin, Joseph Scimeca and Michael Pariza, Cancer Research, 51, 6118-6124, Nov. 15, 1991.
    19. “Refiguring the Odds: What’s a woman’s real chance of suffering breast cancer?” Facklemann, K.A., Science News 144 (1993) 76-77.
    20. “Inhibition of benzo(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid.” Ha, Y.L, Storkson, J., Pariza, M.W. Cancer Research 50: 1097-1101; 1990.
    21. “Protection of Conjugated linoleic acid against 2-amino-3-methylimidazo [4,5-f]quinoline-induced colon carcinogenesis in the f344 rat: a study of inhibitory mechanisims,” Liew, C.; Schut, H.A.J., chin, S.F., Pariza, M.W., and Dashwood, R.H. (1995), Carcinogenesis 16, 3037-3044.
    22. Op. Cit., Ip, Cancer Research, 1991.
    23. “Potential of Food Modification in Cancer Prevention,” Ip, C.; Lisk, Donald J. and J. Scimeca, Cancer Research, 54, 1957-1959, April 1, 1994.
    24. “Conjugated Linoleic Acid (CLA), A Newly Re c o g n i ze d Anitcarcinogenic Nutrient,” unpublished paper by Michael Pariza.
    25. “Effects of conjugated dienoic linoleic acid on lipid metabolism in mouse liver,” Belury, M.A. and Vanden Heuvel, J.P. (1996), Proc. Am. Assoc. Cancer Res. 37: 1918.
    26. “Protection Against Cancer and Heart Disease by Dietary Fatty Acid, Conjugated Linoleic Acid: Potential Mechanisms of Action,” Belury, M.A.; Vanden Heuvel, J.P; Submitted to Nutrition and Disease Update Journal, Sept. 28, 1996.
    27. Interveiw with Pariza.
    28. Op. Cit., Pariza, Cancer Research, 1990.
    29. “Fatty Acids that Inhibit Cancer,” unpublished paper by M. Pariza.
    30. Op. Cit. Liew.
    31. “Reinvestigation of the antioxidant properties of conjugated linoleic acid,” van den Berg J.J.; Cook, N.E.; Tribble D.L.; Lipids, 73, 1995, Jul 30 (7), 595-598.
    32. “Furan Fatty acids detrmined as oxidation products of conjugated octadecadienoic acid,” Yurawecz, M.P., Hood, J.K., Mossoba, MM., Roach, J.A.G., and Ku, Y. Lipids 30, 595-598.
    33. Interview with Pariza.
    34. “Vital Statistics of the United States” from the Centers for Disease Control for 1989.
    35. “Conjugated linoleic acid and atherosclerosis in rabbits.” Lee, K.N., Kritchevsky, D. And Pariza, M.W.; Atherosclerosis 108, 19-25.
    36. Interview with Pariza.
    37. “Dietary conjugated linoleic acid reduces aortic fatty streak formation greater than linoleic acid in hypercholesterolemic hamsters,” Nicolosi, R.J., and Laitinen, L. (1996), FASEB J. 10 A477.
    38. “Ionic Basis of Hypertension, Insulin in Resistance, Vascular Disease and Related Disorders. The Mechanism of ‘Syndrome X”, Resnick, LM, American Journal of Hypertension. 1993 (4Suppl) 123S-134S.
    39. “Protection by Coenzyme Q10 from myocardial reperfusion injury during coronary artery bypass grafting,” Chello-M, et. Al, Ann-Thorac. Surg., 1994, Nov; 58(5): 1427-32.
    40. “Immune Modulation by Altered Nutrient Metabolism: Nutritional Control of Immune-Induced Growth Depression,” M.E. Cook, C.C. Miller, Y. Park and Ma Pariza, Poultry Science 72: 1301-1305 (1993).
    41. “Feeding Conjugated Linoleic Acid to Animals Partially Overcomes Catabolic Responses Due to Endotoxin Injection,” Miller, C.C., Park, Y., Pariza, M, and Cook, M. Feb. 15, 1994, Biochemical and Biophysical Research Communications, pages 1107-1112.
    42. Op. Cit. Cook, Poultry Science, 1993.
    43. Interview with Cook.
    44. Ibid.
    45. Op. Cit. Washington Post.
    46. “Obesity, Pathogenesis & Treatment, a series of reports on obesisy issues edited by G. Enzi, et. Al, 1981, Academic Press.
    47. William Howard Taft: The President who became Chief Justice, by Severn, Bill 1970, David McKay company.
    48. “Conjugated Linoleic Acid Reduces Body Fat,” abstract only of a speech g i ven at En v i ronmental Bi o l o g y, 96. See also U.S. Patent Nu m b e r 5,554,646, dated Sep. 10, 1996.
    49. Interveiw with Cook.
    50. Information of Dr. Parizi provided to PharmaNutrients, Inc.
    51. Interview with Cook.
    52. Op. Cit. Parodi.
    53. Obesity & Weight Control: The Health Pro f e s s i o n a l’s Guide to Understanding & Treatment. Edited by Frankle, R. T. 1988.
    54. Ibid.
    55. Op. Cit. The Washington Post.
    56. Interview with Pariza.
    57. Pariza in information to Pharmnutrients, Inc., indicates a Dr. Reid studied content in 1963 of milk fat.
    58. Op Cit. Parodi.
    59. Bill Phillips, Supplement Review, 3rd Edition.
    60. Interview with Pariza.
    61. Interview with Cook.
    62. Interviews with Cook, Pariza.
    63. Research conducted by Medstat Research Ltd., Lillestrom, Norway for the Herbal Marketing Group, HMG, Ltd., Oslo, Norway. “A pilot study with the aim of stydying the efficacy and tolerability of CLA (Tonalin) on the body composition in humans.) by Erling Thom Ph.D., Medstate Research Ltd., Liilestrom, Norway, July 1997.



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    CLA and Ather osclerosis
    TopPreviousNext

    Date: June 22, 2005 09:47 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CLA and Ather osclerosis

    CLA and Ather osclerosis

    CLA may well have benefits in the battle against heart disease as well. The leading cause of death in the United States is heart disease or related diseases of the circulatory system. Indeed, U.S. statistics show that about half the people in the United States die that way.

    In 1989, for example, some 2 million Americans died, and about 950,000 of those died as a direct or indirect result of heart disease. T h a t’s far more than the total number of deaths fro m AIDS, shootings, bombings and accidents combined.3 4 For pers p e c t i ve, let’s discuss what happens when a new s w o rthy accident o c c u r s — l e t’s say an airline crash that kills 200 people.

    Statistically speaking, five times that many people will die the same day of heart disease, as many as two each minute. Thankfully, doctors have made great progress in battling these conditions, and researchers have discovered that a healthy lifestyle can help the heart. Indeed, as almost everyone knows, balanced nutrition, lower stress and plenty of exercise can lead a person to be more healthy and to run a lower risk of heart attack and other heart conditions. Evidently, at least in animals, CLA seems to possess the ability to cut risks as well. Dr. Pariza and two colleagues, Kisun Lee and David Kritchevsky, studied a group of 12 rabbits that were fed a diet high in fat and cholesterol. They gave six of them CLA. In the academic journal Atherosclerosis, they reported that two dangerous compounds, LDL cholesterol and triglycerides, were “markedly lower” in the six that had diets supplemented with CLA.

    When the scientists looked at the aortas—the largest artery leading from the heart—of these animals, they also found a lot less blockage than in those that didn’t have CLA. This is how they summarized their results: “CLA appears to be hypocholesterolemic and anti-atherogenic.”35 This is pretty bold stuff for cautious scientists. Though the words are complex, the statement is clear: CLA seems to cut cholesterol and makes it so veins won’t clog as easily. This finding was surprising to Dr. Pariza. Science shows that straightened fatty acids (trans-fatty acids) of which CLA is one, usually tend to increase the risk of heart disease. Pariza said it only made sense to test CLA with this kind of science. Indeed, the best he would hope for would be no effect.36 In 1996, another group studied atherosclerosis and hamsters supplementing diets with CLA. CLA didn’t cut the amount of cholesterol in the blood within three months, but it did cut the amount of fatty build-up in the aorta of the hamsters.37 The bottom line on heart disease and CLA? Because two different types of animals show less clogging of the arteries, it seems clear that a good chance exists for the same thing to happen in humans. Of course, as with the cancer research, solid studies in humans need to be conducted for researchers to say definitely that this can cut your risk of heart disease. But until that day, the news is good: A nutritional regimen that includes solid antioxidants like vitamin C and vitamin A, that includes magnesium,38 Coenzyme Q10,39 and that includes other important circulatory system-fortifiers would likely benefit from CLA. Couple that nutrition with a healthful lifestyle, and your chances of living longer and living better will likely increase.

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    Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement
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    Date: June 21, 2005 05:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement

    Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplements

    By Adina Licht, MS

    Adina Licht, M.S. is a Nutritional Scientist and Science Writer who works as a Marketing Specialist for Source Naturals. She has a B.A. in Environmental Science from UC Berkeley, an M.S. in Nutrition and Food Science from San Jose State University, and training in Technical Communication from Cal State Hayward. Her work has appeared in publications such as Advances in Packaging and Development, Health Supplement Retailer and Delicious Living.

    Americans Need More Nutrients

    The U. S. population is drastically malnourished. According to the latest A. C. Nielsen survey, only 12% of Americans claim to eat the 5 recommended servings of fruits and vegetables each day (Warner, 2004). And approximately 1/3 of the calories that people do consume are from nutrient-poor foods such as alcohol and soda (Yang, 2004). This combination has led to a population that consumes too few nutrients, which according to an article in the Journal of the American Medical Association (Fletcher, 2002) puts people at risk for long-term health concerns. With Americans eating fewer healthy foods, taking a daily multiple is one way for people to increase their intake of nutrients. But the search for what defines a good multiple can be confusing, even to health care professionals.

    The Confusing U.S. Government Standards

    Scientists first recognized the need for vitamins in the early 1900s (Levenstein, 1993). But setting U. S. government standards for vitamins and minerals didn't start until healthy soldiers were needed to fight World War II. And when a committee of scientists was asked to determine the levels of nutrients needed to maintain good health they could only agree on "recommended allowances" to prevent deficiency with a wide margin of safety. In 1941, these allowances became the first Recommended Dietary Allowances (RDAs) for the nation (Levenstein, 1993). In 1997, the Food and Drug Administration (FDA) used latest RDAs to set the new Dietary Reference Intake (DRI) standards, which included Adequate Intakes (AIs) for when there was insufficient evidence to determine an RDA, and Upper Intake Levels (ULs) as the safe daily upper limit. To simplify the information, food labels express nutrient information as a percentage of the Daily Value (DV), which includes RDA values for a healthy adult who consumes 2000 calories per day (Whitney, 2002). However, these values do not include AIs or ULs and many individuals need different levels of nutrients than these.

    Confusing Standards equals Confusing Recommendations

    The RDAs and subsequent DRIs are the basis of the nutrient standards for at least 40 different nations and many professional health organizations. Currently, the American Dietetic Association (ADA) recommends that people who cannot reach the DRIs through diet take a multiple with nutrient levels that do not exceed the RDAs (JADA, 2001). And in 2002, the American Medical Association (AMA) published a paper that included a recommendation for all adults to take RDA levels of vitamin supplements in their Journal of the American Medical Association (Fletcher, 2002). Despite the benefits of having guidelines, most people only hear about the RDAs and DVs, which may be too low for preventing deficiencies while the ULs and AIs, which can be much more beneficial are rarely discussed. For example, the Daily Value of Vitamin E to prevent deficiency is 30 IU while the daily Upper Intake Limit is 1,467 IU. But, according to the ADA, as many as 75% of cardiologists recommend vitamin E to their patients to promote heart health, usually at a dosage of 400 IU (ADA, 2001; Meydani, 2004; & Whitney, 1998). And the Daily Value for Vitamin C is 60 mg while the daily Upper Intake Limit is 2000 mg, but in clinical studies it took 500 mg per day to help maintain healthy blood pressure (Whitney, 1998, & Hendler, 2001).

    Alternative Recommendations

    Lyle MacWilliam is a biochemist and former health advisor to the Canadian Ministry of Health, who decided to research, analyze and publish the Comparative Guide to Nutritional Supplements. In this book, the individually published recommendations from seven nutrition experts (Phyllis Balch, CNC, Dr. Michael Colgan, Ph.D., Dr. Earl Mindell, Ph.D., Dr. Michael Murray, N.D., Dr. Richard Passwater, Ph.D., Dr. Ray Strand, M.D., and Dr. Julian Whitaker, M.D.) were combined to create an ultimate blended standard of recommended median intakes for 39 nutrients to promote health. Those nutrients include vitamins, minerals, phytonutrients, and other supplements, that span 14 different health categories and are much closer to the Upper Intake Limit government standards. The guide also includes information about recommended forms, safety, purity and quality (MacWilliam, 2003). One of the most profound differences between MacWilliam?s compiled recommendations and the DRIs is the difference in the number of supplements: 39 vs. 26 respectively. The Comparative Guide standard includes additional nutrients, including many more antioxidants, based on decades of clinical research about their benefits. For example, the fat-soluble antioxidant Coenzyme Q10 that your body manufactures less of as you age is included. So is the fat and water-soluble antioxidant alpha lipoic acid that helps recycle other antioxidants such as vitamins C and E (Hendler, 2001).

    Top Ranked Multiples for Optimal Health

    In the latter half of MacWilliam's book he uses this ultimate blended standard to rank and compare 500 manufactured multiples. Of the five top-ranked multiples, only the Source Naturals multiples, Life Force and Élan Vitàl, are widely available at natural product stores and health outlets. And the new and improved Life Force formulation now rates higher than any of the products evaluated in the current edition of this guide (MacWilliam, 2004; & Mac-William, 2003). The ingredients that can be found in today's multiple supplements can vary greatly. But multiple choices don't have to lead to confusion. Health professionals, such as Lyle MacWilliam, understand the importance of remaining curious, evaluating the available research, and conferring with other scientists to determine the nutrients that support optimal health.

    References

    American Dietetic Association. 2001. Vitamin E: Disease Prevention for your Good Health. American Dietetic Association Website. Available at: Public/Other/index_nfs1001.cfm Fletcher, R. H., & Fairfield, K. M. 2002. Vitamins for Chronic Disease Prevention in Adults. JAMA. (23)287:3116-3129. Hendler, S. S., et al. 2001. PDR for Nutritional Supplements. Thomson Healthcare: Montvale. Pages 11-12, 17-21, 60-62, 103, 416-421, 486-498. JADA (Journal of the American Dietetic Association) 2001. Vitamin and mineral supplementation. J AM Diet Assoc.101: 115 Available at: Public/NutritionInformation/92_8343.cfm Levenstein, H. 1993. Paradox of Plenty: A Social History of Eating in Modern America. Oxford University Press: New York. Pages 13-15, 64-67. MacWilliam, L, et al. 2003. Comparative Guide to Nutritional Supplements. Northern Dimensions Publishing: Vernon. Pages 62-70. MacWilliam, L. 2004. Comparative Guide Individual Assessment of New Life Force Formulation. Warner, J. 2004. Few Follow '5 a Day' Fruit and Vegetable Rule. WebMD website. Available at: ent/Article/93/102158.htm Whitney, N. W., & Rolfes, S. R. (1998). Understanding Normal and Clinical Nutrition, 5th ed. Page 358. Whitney, E. N., & Rolfes, S. R. 2002. Understanding Nutrition. 9th ed. Wadsworth Thomson Learning: Belmont. Pages A, B, Y, 13-20, 55-56, 307, 331, 335-341, 401. Yang, S. 2004. Nearly one-third of the calories in the US diet come from junk food, researcher finds.



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    Pep Up and Go!
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    Date: June 14, 2005 05:45 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Pep Up and Go!

    Pep Up and Go!

    by Harris Parker Energy Times, February 2, 2000

    Feel your energy flagging?

    You've lost count of the number of phone calls you fielded all afternoon-the last was from your son, who missed the late bus home from school-and colleagues needing your decision are lined up outside your office. Your husband has invited clients home for dinner. You wilt like a new hairdo on a damp August day and pray for a miracle to jump-start your engine.

    Your pep quotient depends on three essential ingredients: nutrients you consume through your diet and supplements, how much you exercise and your sleep schedule.(Of course, if you're troubled by any kind of disabling, ceaseless fatigue accompanied by mental fuzziness, joint pain, sore throat, swollen glands, headaches and other chronic distress, consult your health practitioner.)

    Vitamins and Energy

    Certain nutrients are called vitamins because scientists consider them to be crucial for vitality. They generally function as coenzymes, partnering with the enzymes that are catalysts for the chemical reactions constantly taking place in our bodies. Our need to replenish our store of vitamins, which may merge with cell, muscle, enzyme, hormone, blood and bone structure once they have been absorbed, depends on their rate of utilization, according to The Real Vitamin & Mineral Book (Avery) by Shari Lieberman, PhD, and Nancy Bruning.

    While a low-fat diet rich in raw fruits and vegetables helps supply important nutrients, a B complex supplement and a balanced multivitamin can guarantee daily vitamin levels.

    Be Energetic with B Vitamins

    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. The chart on page 39 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their benefit is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances that are called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH), which are critical elements of energy production in the Krebs cycle as well as a process called oxidative phosphorylation.

    Hundreds of Reactions

    Even though you may never have heard of NAD and NADH, these molecules are found in very many places throughout your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend

    The main energy currency of every cell single cell is ATP: a chemical called adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy. (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy

    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP.

    This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    And Don't Overlook. . . . . .other supplements that may aid energy production: • Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors • Coenzyme Q10, also known as ubiquinone as it exists everywhere in the body, acts like a vitamin because it stimulates some reactions. CoQ10 protects cell membranes, especially of the heart, against oxidation and toxins.

    Ginsengs: Energy Generators

    With their legendary and slightly mysterious characteristics, the ginsengs are greatly respected natural energy boosters. " Perhaps no herb has excited so much interest in medical circles as ginseng, and yet, strangely, it does not actually 'cure' any one particular ailment," reports Michael Hallowell, the author of Herbal Healing (Avery) and a frequent lecturer on botanic medicine. "Rather, its virtue lies in its tremendous power as a tonic and invigorator. Russian athletes are prescribed large amounts of ginseng because researchers in Moscow have shown that it not only improves stamina, but also increases the efficiency with which blood is pumped to the muscles."

    What are the physiological mechanisms that allow ginseng to bolster your get up and go? In order to unravel the legend and lore of ginseng, the first step is understanding the intricacies of the three types: • Asian (Panax ginseng), which produces the strongest and most profound stimulation; • American (Panax quinquefolium), which soothes at a more subtle level; • Siberian (Eleutherococcus senticosus), a stamina booster embraced by a wide range of athletes. All three varieties are treasured for their ability to help people adjust to stress.

    Biologically Active

    The ginsengs are adaptogens, "biologically active substances found in certain herbs and plants that help the body and mind adapt to the changes and stress of life," says Stephen Fulder, MD, author of The Book of Ginseng and Other Chinese Herbs for Vitality (Inner Traditions). "Stress is not an illness in itself. Stress is change, our ability to adapt to all the changes that occur in life, emotional or physical, from exercise, work, chemicals, drugs, food, radiation, bacteria, disease, temperature, or simply too many late nights or too much fun."

    The body reacts to stress by producing the hormone adrenaline, which throws the whole body into a state of alert. Metabolism, blood pressure and circulation accelerate; immunity and resistance drastically decline; performance suffers.

    Top-Notch Tonics

    Enter the ginsengs, with their varied, subtle tonic qualities. The Greek name for this herb, "panax," means "panacea" or cure-all. But the Chinese, who first referred to it 2,000 years ago, more literally called it "ren shen" or "person root," in reference to its physical resemblance to a miniature human form.

    " Most exhibit medicinal properties, but each species has a different chemical makeup and has a unique application in Traditional Chinese Medicine (TCM)," says Kim Derek Pritts, author of Ginseng: How to Find, Grow and Use America's Forest Gold (Stackpole). "In general, all true ginseng contains biologically active saponins (chemicals similar to human hormones), essential oils, carbohydrates, sugars, organic acids, nitrogenous substances, amino acids, peptides, vitamins and minerals."

    Building Vital Energy

    All the ginsengs strengthen, nourish and build Qi, the TCM concept describing basic vital energy circulating through our bodies. Every physical and mental function, from breathing, thinking, nutrition and circulation, is regulated by Qi. Although many of the Native American tribes used the abundant, indigenous Panax quinquefolium ginseng extensively, particularly to increase mental acuity and boost fertility, the herb never has been as popular in North America as it is in Asia. American ginseng traditionally has been a lucrative export crop to China, where the wild native variety suffers from overharvesting. Even today, according to Paul Bergner in The Healing Power of Ginseng & the Tonic Herbs (Prima), 95% of the American ginseng crop is exported to China, where XiYang Shen, or "western sea root," as it is called, is immensely valued and costs double what it does here.

    Energy Boost

    Jacques MoraMarco, author of The Complete Ginseng Handbook: A Practical Guide for Energy, Health and Longevity (Contemporary), as well as a licensed acupuncturist and doctor of Eastern medicine, suggests American ginseng for a slight energy boost. The moderate effect of American ginseng is considered a more appropriate tonic to the intensity of our pace and diet.

    Variations on a Theme

    In TCM terms, American ginseng cools and moistens, as well as lubricates and strengthens the body. It is reputed to reduce fevers and night sweats and alleviate hot, dry lung problems like smoker's cough. With its emollient qualities, American ginseng is considered to treat dry, wrinkled skin effectively.

    The Bolder Energizer

    Asian ginseng, which includes red Korean panax, is a bolder energizer taken by those who feel depleted from anemia, blood loss, cardiovascular weakness, injury, shock or trauma, as well as the disabling effects of age. In general, Asian ginseng is warming and stimulating, urging the body to run faster.

    Siberian ginseng, though botanically not a true ginseng, still acts similarly to Asian ginseng in its reputed power to control stress, boost energy, support the immune system, enhance performance and increase longevity. Called Wu Cha Seng in Chinese, Siberian ginseng is perceived by natural practitioners as an ideal herb for the healthy who want to lift both stamina and endurance. Experts believe it counteracts the effects of cortisol, the stress hormone produced by the adrenal glands in response to injury, pain or emotional turmoil.

    Natural Energy Boosters

    The herbal pharmacopeia includes several other natural energy boosters available in various forms-shakes and bars for those on the run-loaded with nutrition absent from commercial snacks. Some choices: • Ginkgo biloba-used in Chinese medicine to heat the body and increase sexual energy. Ginkgo enthusiasts take this herb to increase the supply of oxygen to the brain and generally increase circulation. • Gotu kola-may stimulate the central nervous system and help eliminate excess fluid, thereby reducing fatigue. • Astragalus-a Chinese herb that enhances energy and builds the immune system. It is credited with strengthening digestion, improving metabolism, increasing appetite, combating diarrhea and healing sores. • Schisandra-also a Chinese herb, treats respiratory illness, insomnia and irritability and rejuvenates sexual energy. Its mild adaptogens help the body to handle stress. • Licorice-is a favored endocrine toner in Chinese medicine. It is reputed to support the adrenals, the pair of small glands directly above the kidneys that secrete steroidal hormones, norepinephrine and epinephrine, the "fight or flight" hormones. People with high blood pressure or edema, or pregnant women, should avoid it. • Ashwagandha-an Ayurvedic herb used for thousands of years in the traditional healing of India as a potent strength builder for men and women.

    Experienced herbal practitioners acquire an impressive and fascinating store of knowledge and experience-you'll find it helpful to visit one as you begin your course of ginseng or other energy-boosting herbs.

    TCM Visitation

    When you visit a TCM practitioner, you'll notice that she evaluates your body's condition through an extremely careful examination of all the different systems: Several pulse points are felt in order to ferret out and detect troubling abnormalities. The condition and color of the tongue is observed to decipher digestive disorders. In addition, your urine may be examined to determine other imbalances and specific health problems.

    In many cases, your TCM practitioner will recommend ginseng as an adaptogen that can give you an overall boost. When taking ginseng, follow the directions on the package. Note: in some cases, you may want to consume a little bit less if you suffer headaches, insomnia or high blood pressure. Consult your health practitioner if you are afflicted with either acute inflammatory disease or bronchitis.

    Then take comfort in the eternal soothing wisdom of Chinese Traditional Medicine. In the first century A.D., the Shen Nong Ben Cao Jing (The Divine Husbandman's Classic of the Materia Medica) effusively described ginseng and the tonic herbs in this beguiling and intriguing manner: "The first class of drugs...are considered to perform the work of sovereigns. They support human life and they resemble heaven. They are not poisonous regardless of the quality and duration of administration."



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    Acupuncture nutrient Connection
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    Date: June 12, 2005 05:53 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Acupuncture nutrient Connection

    Acupuncture nutrient Connection by Robert Gluck Energy Times, November 1, 1998

    The theory behind the practice of acupuncture confounds western science. This therapy, originating in Asia, is based on the concept that currents of energy called meridians flow through your body. However, no one has ever been able to conclusively demonstrate the existence of these meridians.

    Despite the evasiveness of these energy streams, Traditional Chinese Medicine (TCM) holds that alterations in these energy flows can disrupt health and cause pain. Consequently, an acupuncturist punctures your skin with specialized needles to redirect the body's vital energy.

    Alleviating Illness

    Despite the fact that western scientists have not been able to find satisfactory evidence of the existence of these energetic meridians, studies show that acupuncture works and is especially effective at relieving pain. This therapy has been used to alleviate a variety of conditions including chronic pain, nausea and even mental illness. In addition, some practitioners apply it to those trying to shake off the chains of drug addiction. (More recently, many practitioners now also successfully use acupuncture to relieve physical problems in animals.)

    Of course, no matter what your perspective on this therapy, acupuncture's no panacea. While you might use acupuncture to relieve the discomforts of chemotherapy, you wouldn't use this technique as your primary weapon against a dangerous disease like cancer. Still, this reliable therapy occupies a welcome spot as an adjunct to many mainstream therapies. Consequently, many mainstream practitioners accept the validity of using acupuncture and many managed care companies reimburse this therapy. Some HMOs even keep a list of approved acupuncturists that they make available to enrollees.

    Acupuncture East and West

    The practice of acupuncture dates back at least 2200 years ago in Asia. Only during the last forty years has it become well-known and widely available in the United States. Today, 29 accredited acupuncture schools train practitioners in North America. In addition, traditional healers in Belize (south of Mexico) have been found to use a form of acupuncture derived from traditional Mayan medicine.

    Is the use of acupuncture by Mayan shamans coincidence? Or further evidence that acupuncture meridians really exist? No one knows for sure, although some experts believe the Mayan use of this therapy supports the notion that the original ancestors of the Mayans migrated from Asia.

    Needle Relief

    Acupuncturists insert needles into the body to relieve pain or enhance bodily functions. TCM holds that acupuncture, and the manipulation of these tiny needles, moves and manipulates qi (pronounced chee), the body's energy force.

    "Acupuncture is a method of balancing the body's energy," says Carol Alexander, an acupuncturist at the North Jersey Health and Pain Relief Center in Hackettstown, New Jersey. "Disease occurs because of an imbalance...Insertion of the acupuncture needles into meridians will bring about the balance of qi." Alexander has practiced acupuncture for 10 years and studied at the Tri-State School of Traditional Acupuncture in Stanford Connecticut.

    Alexander says patients sometimes suffer a blockage of qi or display too much or too little qi. The manipulation and placement of the acupuncture needles vary according to the need for adjusting meridian energy flow.

    Acupuncture can be used to prevent disease and, if disease is already rampant, it can be used to help the body correct the problem.

    In conjunction with her use of acupuncture needles, Alexander rarely prescribes single herbs but uses combinations of whole herbs that are very specific for different diseases and disease patterns. "Certain herbs, such as ginseng, are very prized in Chinese medicine," Alexander notes.

    "Astragalus is an herb used in China and around the world to tonify the qi and increase qi energy as well as stimulate the immune system."

    Licorice Root

    Alexander uses licorice root for assisting digestion and for helping women with menopausal discomforts. On the other hand, she recommends whole food concentrates like bee pollen granules for enhancing the immune system, peppermint for treating gastro-intestinal problems plus fiber supplements as well as the antioxidant/antihistamine quercetin, Coenzyme Q10 and melatonin.

    "In terms of classes of nutrients, I use a lot of whole food concentrates: the green concentrates like barley greens, wheat grass powder, spirulina and blue-green algae," Alexander says. "These are high in minerals, antioxidants, nutrients and fatty acids. I also use some soy products because the isoflavone concentrates are very much anti-cancer."

    The Fine Points of Acupuncture

    Acupuncture needles are very fine, as thin as hairs. They are available in a variety of diameters and lengths. When an acupuncturist inserts these needles, the sensation is that of mild pinpricks. (The needles enter the body at depths of only 1/8th inch to two inches.) In many cases people experience mild pleasure during needle manipulation.

    "From a Western point of view it's important to explain that there is a distinct function of acupuncture treatment and that is to increase circulation," Alexander says. "We do stimulate nerves and we know that with the stimulation of nerves many neurochemicals and neurotransmitters are released. They move through the nerves and find receptor sights, some in the brain, some in other parts of the body."

    By stimulating nerves, acupuncturists can calm inflammation and deaden pain. These effects are believed to be linked to the release of endorphins and dinorphins, powerful painkillers and anti-inflammatories that the body produces for itself. Most acupuncturists use this therapy as part of an overall, multi-faceted treatment plan.

    Unique Energy

    "Qi is what makes you different from a sack of chemicals," points out David Molony, an acupuncturist at the Lehigh Valley Acupuncture Center in Catasaqua, Pennsylvania who studied at the Nanjing Traditional Medicine Hospital in China and has lectured at Cornell University.

    What You Need

    "You can manipulate qi with acupuncture, herbs and diet. Because people's bodies work differently, there are different approaches. When you ask the question what nutrients and herbs are effective at enhancing acupuncture, it depends on what the person needs, according to an Oriental Medicine diagnosis."

    An Oriental Medical examination, Molony says, begins with a long list of health questions designed to reveal factors that contribute to disease. A practitioner measures your pulse in several different places along your arm, inspects your tongue, may press on your stomach, sniff your general odor and closely examine your nails and skin for signs of problems.

    "You take in everything you can," adds Molony, a board member of the Acupuncture Society of Pennsylvania and former board member of the American Association of Acupuncture and Oriental Medicine. "This gives you clues that you need in order to make your diagnosis."

    Acupuncturists use nutrients and herbs that complement the treatment, as well as dietary and lifestyle counseling. Some acupuncturists don't specialize in herbal remedies, so these practitioners might go to a specialist like David Winston for advice. Winston, an herb expert skilled in Cherokee, Chinese and Western eclectic herbal medicine, works as an instructor, lecturer and consultant.

    "In China, acupuncture is considered a complementary therapy; you generally don't go for treatment and get purely acupuncture," says Winston who is working on a book about saw palmetto. "Herbal medicine, diet and qi gong are important therapies in their own right and acupuncture is one of those therapies. Qi gong is a form of martial arts that focuses on unique breathing and visualization methods. Qi is not exactly energy, it's energy in movement; it's what makes the blood move."

    Open Blockages

    Acupuncture is used to open blockages that sometimes build up in what TCM practitioners characterize as excessive heat or cold. These hot and cold spots do not always literally refer to the temperature of the body but are meant to depict changes in the character of the body's vital energy.

    Chinese acupuncturists don't necessarily treat diseases, but target clusters of physical discomforts. Winston says, "Herbal formulas change depending on the 'symptom pictures.' Somebody could have acute appendicitis but the symptom picture could vary. Usually Chinese acupuncturists use herbs like isatis (a very cold, drying herb that's a powerful anti-bacterial agent) and coptis (a powerful anti-bacterial herb)."

    Americans often visit acupuncturists complaining of back pain or some type of musculoskeletal problem-a wrenched knee, a ligament that hasn't healed properly or perhaps a torn rotator cuff. "If the injury is hot to the touch, it's red, it's inflammatory-that's a condition where there's excessive heat and in that condition the acupuncturist would give herbs that are cooling and anti-inflammatory such as the root of large leaf gentian."

    Pain that Moves

    If someone suffers pain that moves, pain that is sometimes exacerbated by damp or humid conditions, acupuncturists often prescribe clematis root, a wild variety of the garden plant that is an anti-spasmodic, or acanthopanax, a relative of Siberian ginseng used for damp pain.

    "If there's pain with excessive dampness," Winston says, "acupuncturists might use duhuo, a drying herb that opens the meridians."

    Molony agrees with Winston that when it comes to choosing herbs to enhance acupuncture, accurate analysis of the root cause of the health problem is paramount to making the right decisions. For example, if a person is qi deficient and her tongue is thickly coated, she may not be processing her energy properly. Phlegm builds up, decreasing energy. "What you want to do is give them herbs that move phlegm, like citrus peel, and combine that with acupuncture points that move phlegm also," Molony says.

    For stimulating metabolism, Molony uses lactoferin-processed colostrum from cows. He uses ginseng and atractylodes as qi tonics and he adds herbs like magnolia bark or atractylodes alba.

    Helpful Antioxidants

    He believes antioxidants are helpful too, as preventive medicines, including vitamins C and E. These valuable nutrients disarm the harm that reactive molecules can wreak within the body.

    So how important are herbs and nutrition to enhance acupuncture's effectiveness? Acupuncturists seem to agree that healthy doses of antioxidants (such as vitamins C and E plus antioxidants from grapeseed extract) as well as specialized herbs, turn this therapy into a highly effective healing tool. Those wanting to benefit from this penetrating technique should stock up on nutrients. Then sit back, relax, kick off your shoes and let the acupuncturist do her stuff.



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    Maximum Absorption
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    Date: June 10, 2005 03:24 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Maximum Absorption

    Maximum Absorption

    by Henry Wolfe Energy Times, July 11, 2003

    Nutrients do you no good if you don't absorb them. Eating the right stuff and taking the right nutrients can still be wrong if they never make it out of your digestive tract and into your bloodstream.

    For instance, dietary supplements usually should be taken along with food. The presence of food in the digestive tract aids the absorption of nutrients. As a general rule, if you take dietary supplements on an empty stomach, most of their contents will probably pass through you and never escape your intestinal tract before they are eventually eliminated. This is particularly true for the fat-soluble nutrients such as vitamins A, D and E. By consuming fatty foods when you take these supplements, you enable your body to absorb a large amount of these valuable substances.

    But there is at least one exception to this rule: Amino acid supplements (protein building blocks) should usually be taken on an empty stomach. Otherwise the other amino acids present in your meal may interfere with your use of these nutrients and counteract the benefits of the supplements.

    The Standardization of Herbs

    Taking herbs presents different challenges than consuming dietary supplements. While the chemical structures of nutrients in supplements are usually precisely identified, the active ingredients in herbs is usually a mixture of chemicals. Often, too, researchers disagree on exactly which active ingredients in herbs produce the health benefits linked to these botanicals.

    But in an effort to derive the most from these substances, many experts recommend what are called standardized forms.

    Standardized herbal supplements are formulas that have been created to insure they contain consistent and reliable amounts of certain beneficial chemicals that scientists have identified in these plants.

    In the creation of these supplements, experts determine the standardized chemicals that are most likely the basis of the herbs' effectiveness.

    By standardizing certain of the supplements' ingredients, therefore, standardized herbs limit the variation among batches of the product. You can rely on the fact that every purchase will contain the same amount of ingredients taken from the original plant. According to Michael Janson, MD, author of Dr. Janson's New Vitamin Revolution (Penguin/Avery), "Although herbs have a long history of use for medicinal purposes, it is only recently that they have been analyzed to reveal their most active components. These active chemicals are commonly present in very variable amounts in herbs, depending on where and how they are grown, soil quality, when they are harvested, the amount of rain and sun, and other factors.

    "Standardized herbs have guaranteed specific amounts of the known, active herbal components, as well as the other factors that might be of help but are not as well studied" (www.drjanson.com).

    Herbalists who specialize in using entire plants in their practices can recommend non-standardized preparations that you can often use.

    In general, that kind of herbal use is more effective when you secure expert advice. If you lack access to an experienced herbalist and you're choosing botanicals on your own, standardized preparations are easier to take.

    Absorption From the Gut

    Most of the nutrients you take in are absorbed through the walls of your digestive tract. This most often takes place in the small intestine.

    What to watch out for: Fast food, fast living and long work hours afflicts our digestion and can disrupt proper absorption. You have to be relaxed to properly absorb the nutrients in your food and supplements.

    Consequently, the occasions for meals should be relaxed and enjoyable moments. Set aside enough time to appreciate, taste and thoroughly chew your food. Adequate digestion and absorption begin in your mouth.

    Another way to increase nutrient absorption is with the use of digestive enzymes. Since the digestive tract depends on the enzymatic breakdown of food that reduces nutrients to absorbable form, taking enzymes can help your intestines make better use of nutrients as they pass through the digestive tract. Normally, enzymes are present in raw food, like uncooked fruits and vegetables. Since most of our food is eaten after it is heated, a process that breaks down enzymes, not many enzymes are present in today's diet. Therefore, taking supplemental enzymes may increase absorption.

    Beyond Stress

    Beyond everyday stress, a variety of problems can make absorption go astray, allowing important nutrients to escape and permitting unwanted substances to enter the body. For instance, a significant digestive malfunction that many experts have focused on in recent years is a condition that has come to be called "leaky gut."

    As Anil Minocha, MD, director of digestive diseases at the Mississippi Medical Center and author of Natural Stomach Care (Avery), points out, "In a healthy individual, the wall of the intestinal tract is designed to absorb food molecules and prevent harmful microorganisms and toxic materials from passing out through the bowel wall and into the bloodstream. "In today's heavily polluted environment, the gastrointestinal tract of even the healthiest individual is called on to process an overwhelmingly large flow of septic and infectious materials."

    Because of these digestion destroyers, as we take in a startlingly large amount of viruses, bacteria, toxic chemicals, fungi and processed foods, our digestive systems are often overwhelmed and are rendered unable to perform their tasks correctly. This constant assault on the stomach and intestines takes a serious toll. A frequent product of this process is the digestive walls' loss of their crucial ability to keep out unwanted toxins and organisms as they become, in Dr. Minocha's words, "loosened and inflamed." As a result, instead of keeping out harmful substances and absorbing helpful nutrients, spaces open up that begin to allow in "bulky, partially digested food particles, toxic substances and infectious microbes."

    According to Dr. Minocha, the first signs of this absorption problem can include complaints such as allergic reactions, skin problems, joint pain, digestive difficulties, nausea, fatigue and lack of energy.

    To improve your digestive absorption, Dr. Minocha recommends a six-part program that includes these steps:

    * Detoxification by means of fasting and avoiding harmful items like sugar, over-processed foods, coffee and alcohol

    * Taking herbs that can help the digestive tract heal, recover and repair itself; these include garlic, ginger and milk thistle

    * Replenishing the beneficial bacteria of the digestive tract by eating yogurt

    * Keeping track of your daily diet and eliminating foods that cause allergies and other reactions

    * Consuming more fruits and vegetables while eating a high-fiber, mostly vegetarian diet

    * Developing consistent, healthy lifestyle habits; these include not smoking, cutting the size of your meals and eating in moderation, exercising several times a week and controlling stress

    Young and Old Digestion

    The nutrients in your diet can also beneficially influence the state of your digestive system and its ability to distinguish among substances that are supposed to gain entrance to your body and those that should be kept out. Since aging can further compromise the discriminatory ability of your gut, Dr. Minocha also recommends a steady diet of antioxidant-rich fruits and vegetables plus supplements to keep your digestive tract functioning at full capacity as you grow older.

    Among the nutrients he recommends:

    * Coenzyme Q10: By middle age, your body makes less of this powerful antioxidant that helps cells generate energy in the mitochondria (structures within cells that may decrease with age).

    Dr. Minocha notes that research demonstrates CoQ10 may be able to help people with diabetes control harmful metabolic byproducts that appear in their bloodstreams.

    * Natural Lycopene: This antioxidant, responsible for the red of both tomatoes and watermelon, has been shown to lower the risk of both heart disease and prostate cancer. As an antioxidant, natural lycopene also helps protect the digestive tract.

    Absorption of the proper nutrients may be the key to health for many people. By paying closer attention to the well-being of your digestive tract and practicing lifestyle habits that promote maximum absorption, you may be able to substantially improve your nutrition and your health.



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    Cross Training
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    Date: June 10, 2005 02:48 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cross Training

    Cross Training

    by column Energy Times, April 1, 1999

    If you've ever felt burned out, bored and/or just plain tired of your exercise program, you may be in need of a taste of cross training. When your exercise routine becomes too routine, you run not only the risk of losing your motivation for physical activity, but you may also run an added chance of injury. The possible cause: overusing particular muscles that receive an excessive amount of stress as other muscles practically atrophy while waiting for a chance to show off their stuff.

    For instance, if you are a devoted runner who spends hours jogging, your upper body may wither unless you give it a reason not to. At the same time, your achilles, hamstrings, knees and lower back muscles may protest those miles after miles. As Frank Jobe, MD, Neal EllAttrache, MD, and Karen Mohr, PT, point out in Athletic Forever (Contemporary), "Dedicated runners are among the most injury-prone of all athletes. If running is your main form of exercise, you have a 37 to 56 percent chance of sustaining an injury each year and your chances for a recurrence of that injury are as high as 70 percent."

    Simple Principle

    The basic principle of cross training is simple: take part in various activities that supplement each other. Runners should lift some weights or at least shoot a few hoops to keep those arms and shoulders toned. Bikers should walk or run now and then to keep their bones healthy. (Bicycling, since it is not a weight bearing exercise, does little to promote bone strength.) Swimmers should find something to do on dry land so that their bones react to gravity and grow stronger. And, no matter what your sport, you should stay well-nourished and supplied with plenty of antioxidants.

    As Stephen T. Sinatra, MD, points out in Optimum Health (Bantam), while athletes may enjoy health benefits from exercise, "The vigorous training pursued by competitive athletes renders them more prone to catabolic stress-a situation in which tissues are constantly broken down."

    He goes on to point out that the low fat diet many athletes follow may be short of antioxidant nutrients. Unfortunately, that shortage can lead to injury. The metabolic acceleration caused by athletic activity may increase potentially harmful oxidative stress at the cellular level. Without antioxidant nutrients to help quell that stress... Well, the results may not be pretty. Potentially, that kind of oxidative damage may, theoretically, lead to cancer or heart disease. As Dr. Sinatra says, in those circumstances, "the supplemental use of glutathione, vitamins C and E, Coenzyme Q10 and magnesium seems reasonable. Some athletes, such as menstruating women, may also need iron supplementation."

    In addition, water is crucial for athletes to stay adequately hydrated during activity. According to Daniel Gastelu and Fred Hatfield, PhD, in Dynamic Nutrition for Maximum Performance (Avery), when you run short of water "this can adversely affect performance and, in the long run, can cause peaks and valleys in the athlete's performance." In addition, they advise using sports drinks to stay adequately supplied with electrolytes. "The major electrolytes found in bodily fluids are chloride, magnesium, potassium and sodium."

    Electrolytes serve a host of duties, including keeping the heart muscle functioning properly. Gastelu and Hatfield explain, "An electrolyte is an ion that is required by the body to regulate the electric charge and flow of water between the cells and the bloodstream."

    Getting Better All the Time

    Even if you cross train religiously and try to avoid overdoing one particular sport, sooner or later you may incur injury. If you do (or even before you hurt yourself), the trio of Stanley W. Jacob, MD, Ronald M. Lawrence, MD, PhD, and Martin Zucker, authors of The Miracle of MSM (Putnam), believe that methylsulfonylmethane (MSM) can provide reliable relief for pain and suffering.

    "Many people experience rapid relief after starting MSM," say this trio. They go on to claim that "this nutritional supplement has real potential to make a significant impact on the quality of life."

    "Your main enemy in the hours following an injury is inflammation," warns Athletic Forever. For injury, they recommend RICE: rest, ice, compression and elevation. In other words, put the injured body part in a firmly wrapped bandage (don't cut off the circulation!) Keep the injury cold but don't put ice directly on it (watch out for frost bite). Rest a while and keep the injury elevated. Then, don't exercise again until you've fully recovered.



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    Menopause Multiple - Eternal Woman
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    Date: June 03, 2005 05:54 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Menopause Multiple - Eternal Woman

    Menopause

    Menopause happens to all women, but affects each woman uniquely. For some, the end of fertility (and the end of concerns about contraception) brings a sense of freedom. For others, it is a time of troublesome symptoms or perhaps the need for certain lifestyle adjustments. Menopause is a bridge to a point in life when many women report feeling more confident, empowered and energized than in their younger years. MENOPAUSE MULTIPLE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems: hormonal regulation, bone metabolism, cardiovascular health, energy generation and circulation.

    After menopause, the ovaries no longer secrete two critical steroid hormones in the amount or pattern characteristic of a regular menstrual cycle. These two hormones are estrogen and progesterone. The transition from regular ovarian function to its absence is often called the perimenopause or perimenopausal transition. The time involved can range from one to 10 years. More than one third of the women in the United States, about 36 million, have been through menopause. With a life expectancy of 81 years, a 50-year-old woman can expect to live more than one third of her life after menopause. Low estrogen levels are linked to some uncomfortable symptoms in many women. The most common and easy to recognize symptom is hot flashes -- sudden intense waves of heat and sweating. Some women find that these hot flashes disrupt their sleep, and others report mood changes. Other symptoms may include irregular periods, vaginal or urinary tract infections, urinary incontinence (leakage of urine or inability to control urine flow), and inflammation of the vagina. Because of the changes in the urinary tract and vagina, some women may have discomfort or pain during sexual intercourse. Many women also notice changes in their skin, digestive tract, and hair during menopause. Because the menopausal years place unique nutritional demands on a woman’s body, Source Naturals created MENOPAUSEMULTIPLE. This comprehensive formula brings together optimal amounts of the finest phytonutrients and herbs--including genistein, black cohosh, and chaste berry--plus vitamins and minerals known to support the biochemistry of mature women.

    Bio-Aligned Formula™

    MENOPAUSE MULTIPLE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with female hormone function.

    Hormonal Regulation

    Hot flashes are related to hormone levels. As estrogen declines, FSH and LH (folliclestimulating and luteinizing hormones) increase, causing blood capillaries to dilate. This brings more blood and higher temperatures to the skin. Soy isoflavones and other herbs can mimic the effects of estrogen. Support for the adrenal glands is important since they account for most estrogen production after menopause.

    Musculoskeletal System

    During and after menopause, a woman’s hormonal balance and biochemistry change. Lower estrogen levels may affect bone density. Phytonutrients and calcium are important to maintain healthy bones in postmenopausal women. Calcium and magnesium work together in the metabolism of bone.

    Heart & Circulation

    Menopause increases concern for the health of the heart and circulatory system. Soy isoflavones and other ingredients may help maintain healthy cholesterol levels. To regulate homocysteine levels for cardiovascular health, vitamins B-6, B-12, and folic acid are critical.

    Liver Support

    Among its many functions, the liver has the important job of promoting hormonal balance by processing excess levels of hormones. The powerful antioxidant, N-acetyl cysteine, helps the liver detoxify chemicals and milk thistle is a liver protectant.

    Energy Generation

    The fatigue that is common during menopause makes nutritional support for energy and metabolism especially important. Metabolism can influence weight, energy levels, and mood. MENOPAUSE MULTIPLE contains ingredients that support energy generation, including the advanced nutrients CoQ10 and lipoic acid and ginkgo biloba.

    Antioxidants: Anti-Aging

    Antioxidants help protect the circulatory system, which is important as estrogen declines. Antioxidants also defend tissues and cell membranes in all your body systems from free radicals, which are formed during normal cellular metabolism. Some important antioxidants: vitamin E, vitamin C, selenium, zinc, and manganese all have strong antioxidant powers.

    Lifestyle Tips for a Healthy Transition

    Get Moving. Exercise is a powerful remedy for many menopause complaints and may help prevent future menopause-related diseases. It promotes better, more restorative sleep, and it stimulates production of endorphins, or “feel good” brain chemistry. Some women report having fewer hot flashes when they exercise regularly. Eat Well. A balanced diet low in saturated fat and high in whole grains, fruits and vegetables, with adequate water, vitamins and minerals contributes to good health. Women at perimenopause and beyond have special dietary concerns, because both heart disease and osteoporosis are greatly affected by diet. A balanced diet is also important for bone development and maintaining bone strength. Some women – especially those who are elderly and have reduced appetites, who diet frequently, who don’t consume diary products, or who have eating disorders – may not consume adequate vitamins and minerals to maintain optimal bone mass. There is evidence that the natural, estrogenlike compounds in soybeans and many other plant foods used in MENOPAUSE MULTIPLE may reduce hot flashes and vaginal dryness and increase bone density in women after menopause. Studies suggest that body cells respond to plant estrogens as if they were weaker versions of the human hormone. So consuming more of these estrogen-mimicking compounds may help compensate for the loss of estrogen naturally as women age. Prevent Bone Loss. Osteoporosis is one of the most preventable of bone diseases. Exercise maintains the strength of bones through aerobics, stair climbing, hiking, or walking. Prevention focuses on nutrition for bones, including a sufficient calcium intake of 1000 to 1500 mg/day.

    Musculoskeletal System: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Boron, Calcium, Magnesium, Manganese, Vitamins A, B-6, B-12, C, D & E, Folic Acid

    Heart and Circulation: Black Cohosh, Coenzyme Q10, Dong Quai, Licorice, Soy Isoflavones, Magnesium, Vitamins B-6, B-12, & E, Folic Acid

    Hormonal Regulation: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Vitex, Vitamins B-5 & C

    Liver Support: Coenzyme Q10, N-Acetyl Cysteine, Dandelion, alpha-Lipoic Acid, Silymarin, Selenium, Vitamin C, Biotin

    Antioxidant Defense: Coenzyme Q10, N-Acetyl Cysteine, alpha-Lipoic Acid, Silymarin, Selenium, Zinc, Vitamins A, C & E

    Energy Generation: alpha-Lipoic Acid, Coenzyme Q10, Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-5, & B-6, Niacinamide

    References
    Abraham, G.E. & Grewal, H.G. 1990. JRM, 35:503. Anderson, J.W., et al. 1995. The New England Journal of Medicine, 335(5): 276-82. Avioli, L. V. (1993). Calcium and Bone: Myths, Facts and Controversies in the Osteoporotic Syndrome: Detection, Prevention and Treatment, 3rd ed. (Avioli ed.) New York: Wiley-Liss. Christy, C.J. 1945. American Journal of Obstetrics & Gynecology, 50:45. Colborn, Theo. 1996. Our Stolen Future. New York: Dutton. Murkies, A.L., et al. 1995. Maturitas, 21:189-95. Nielsen, F.H., et al. 1987. FASEB J, 1:394-97. Raines, E.W., & Ross, R. 1995. Journal of Nutrition, 125:624S-30S. Tranquilli, A., et al. 1994. Gynecological Endocrinology, 8(1):55-8.



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    NutraSpray in Melatonin, Proanthodyn, and St. John's wort
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    Date: June 03, 2005 05:35 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: NutraSpray in Melatonin, Proanthodyn, and St. John's wort

    NutraSpray

    NUTRASPRAY represents a quantum leap in the evolution of supplementation, an elegant combination of convenience, fast action, bioavailability, and sustained release delivery. Source Naturals has long championed the sublingual delivery system, and our Super Sublingual™ is the latest step in the science of nutrition. A quick spritz of NUTRASPRAY under the tongue delivers thousands of microscopic lipid spheres, each full of nutrients. These lipospheres are readily absorbed and retained by the mucosal tissue of the mouth. Here they release their nutrients quickly, but steadily, into the bloodstream – creating a Super Sublingual, the most bioavailable supplement today.

    Nutrient delivery systems include tablets, capsules, softgels, and liquid extracts. Their purpose is to ensure the cells in your body get the nutrients they need from the supplements you take. Sublinguals bypass the digestive system – and its potentially destructive juices – by dissolving under the tongue to be directly absorbed into the bloodstream. Tests show that the NUTRASPRAY liposome sublingual delivery system is more efficient than traditional sublinguals.

    The First Timed Release Sublingual

    Due to the multi-layered structure of the tiny lipospheres, nutrients are gradually released for extended periods of time, maintaining optimal dosage throughout the day or night. This combined with a faster onset of the active ingredients – usually within 15 minutes – makes NUTRASPRAY the most bioavailable delivery system for nutritional supplements today, and the first truly timed release sublingual.

    Unparalleled Convenience

    NUTRASPRAY incorporates a simple, non-aerosol spray pump that’s easily carried in purse or pocket. Its modern functional design is a perfect complement to today’s active lifestyle. It’s easy to regulate nutrient amount, because the convenient pump delivers a specific amount of nutrient-rich liposomes with every spray, and each 2 fl. oz. recyclable plastic bottle can deliver 80 full sprays. Stevia is added as an ingredient in each NUTRASPRAY product.

    Advanced Research

    The lipid micro-encapsulation process is based on years of research in liposomal technology. The result is NUTRASPRAY, a proprietary system to deliver nutrients in the most efficient manner. This sublingual oral spray is a liquid suspension of liposomes, which are nutrients encased in very complex microscopic lipid spheres, 1/50th the diameter of a human hair. A highly purified natural lecithin forms the membrane of these lipid spheres, which are able to move easily through the lipid environment surrounding the capillaries in the mouth. Lipospheres then gradually release their nutrients into bloodstream.

    Nutrients That Go To Your Head

    The Source Naturals NUTRASPRAY line includes natural supplements that are particularly well-suited to this Super Sublingual delivery system, such as Melatonin, Ginkgo Biloba, Coenzyme Q10, Grape Seed extract, and Kava. That’s because these nutrients need to reach the brain for maximum benefit. Also, they’re usually taken for reasons that the fast-acting quality of NUTRASPRAY satisfies. Another unique reason NUTRASPRAY is so bioavailable is that its nutrients bypass the liver on their first pass through the circulatory system. This ensures the nutrient is available to the brain for maximum potency. Source Naturals NUTRASPRAY MELATONIN delivers 1.5 mg of the finest quality Melatonin with each full spray, easily allowing customers to control their intake. Melatonin is ideally suited to the fast-acting nature of NUTRASPRAY, which maintains a more balanced release of Melatonin throughout the night. Source Naturals NutraSpray GINKGO-24™ provides 60 mg of Ginkgo Biloba per full spray. This makes Ginkgo’s beneficial constituents readily available to the capillaries in the blood-brain barrier, facilitating oxygen flow to the brain. CoQ10 is fat soluble; therefore encapsulating it in a lipid is the perfect way to ensure its bioavailability. Each full spray of Source Naturals NUTRASPRAY™ COQ10 yields 30 mg of CoQ10. Furthermore, this popular metabolic enhancer is very experiential with the NUTRASPRAY delivery system. NUTRASPRAY GRAPE SEED extract delivers 50 mg per spray of proanthocyanidins standardized to 95%. These highly bioavailable flavonoids are able to cross the blood-brain barrier, offering potent antioxidant protection to precious neurons. NUTRASPRAY KAVA KAVA is a potent extract standardized to a potent 40% kavalactones, the active constituents of this traditional root from the Polynesian cultures of the South Pacific. The relaxing action of Kava works through the brain’s limbic system, which regulates emotions related to survival issues, including the “fight or flight” response. Each spray yields 60 mg of Kava. Look for other fine products soon to come out in the Source Naturals line of NUTRASPRAYS. Source Naturals built its reputation on bringing the latest nutritional research to market, using the finest ingredients in substantial quantities – for an experience of wellness and vitality you can feel. Source Naturals NUTRASPRAY is a major step toward empowering people to achieve optimal health in a challenging world.



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    Higher Mind - Smart Nutrients for the Performance of a Lifetime...
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    Date: June 02, 2005 12:18 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Higher Mind - Smart Nutrients for the Performance of a Lifetime...

    Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.

    To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.

    Brain Cells – Issued at Birth

    Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.

    Brain Cell Membranes

    The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain.

    Phosphatidyl Serine – Key to Cognition

    For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4

    The Chemistry of Thought

    Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.

    Total Nutrition for the Brain

    The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.

    The Importance of Magnesium

    Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.

    B is for Brain Vitamins

    HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.

    Brain Power

    Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and Coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.

    For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.

    References
    1. Palmieri, G., et al. (1987). Clin. Trials J. 24: 73- 83.
    2. Crook, T.H., et al. (1991). Neurol. 41: 644-49.
    3. Nunzi, M.G., et al. In Phospholipids: Biochemical, Pharmaceutical and Analytical Considerations (ed. I. Hanin and G. Pepeu).
    New York: Plenum Press, 1990.
    4. Heiss, W.D., et al. (1993). Annals N.Y. Acad. Sci. 695: 327-31.
    5. Passeri, M., et al. (1990). Int. J. Clin. Pharm. Res. X(1/2): 75-79.
    6. Kohjimoto, Y., et al. (1988). Japanese Journal of Pharmacology 48(3): 365-71.
    7. Philpott, William H. Brain Allergies: the Psychonutrient Connection. New Canaan: Keats, 1987.
    8. Passariello, N., et al. (1983). Int. J. Clin. Pharmacol. Ther. Toxicol. 21: 252-56.



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    Heart Science - A Five-Tiered Approach to Heart Health ...
    TopPreviousNext

    Date: June 02, 2005 12:07 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

    Heart Science 30 tabs

    Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

    Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

    Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
    1) generating energy,
    2) decreasing harmful homocysteine levels,
    3) fighting oxidized cholesterol,
    4) maintaining the heart’s electrical rhythm, and
    5) protecting artery and capillary linings.

    Energy Generators for An Energetic Organ

    Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

    There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

    CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

    Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

    Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

    HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

    Homocysteine Regulators

    B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

    The Dangers of Oxidized LDL Cholesterol

    While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

    When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

    The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

    Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

    Cholesterol Fighters

    Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

  • • Beta Carotene, a plant pigment, is the naturally occurring precursor to Vitamin A. When the body takes in high enough amounts of Beta Carotene, this lipid-soluble free radical scavenger concentrates in circulating lipoproteins and atherosclerotic plaques, where it performs its antioxidant functions. Beta Carotene is particularly unique and powerful as an antioxidant because it is capable of trapping a very toxic form of di-oxygen, called singlet oxygen, which can result in severe tissue damage. Beta Carotene is one of the most efficient quenchers of singlet oxygen thus far discovered. Six tablets of HEART SCIENCE provide an unprecedented 45,000 IU of Beta Carotene!
  • • Vitamin C is found in plasma, the watery component of blood, where it functions as a potent antioxidant. In addition to strengthening artery linings through collagen manufacture, Vitamin C is involved in the regeneration of Vitamin E within LDL particles. Vitamin C also plays an important role in the conversion of cholesterol into bile acids by the liver, a crucial step in reducing blood cholesterol levels. Once converted into bile acids, and then into bile salts, cholesterol can be excreted from the body, preventing build-up. Supplementation with Vitamin C may lower levels of LDL cholesterol and increase those of HDL cholesterol.25 It may also have a part in actually removing cholesterol deposits from artery walls — good news for people who are already experiencing plaque buildup.25 Each daily dose of HEART SCIENCE provides 1,500 mg of Vitamin C in its bioactive mineral ascorbate form.
  • • Vitamin E, together with Beta Carotene, protects lipids from free radical attack. It is the major antioxidant vitamin that is carried in the lipid fraction of the LDL particle, where it protects the LDL particle from damaging oxidation. Within an LDL particle, one molecule of Vitamin E has the ability to protect about 200 molecules of polyunsaturated fatty acids from free radical damage! Vitamin E also aids in protecting the heart by interfering with the abnormal clumping of blood cell fragments, called platelets, within blood vessels.4 It has been shown to inhibit the formation of thromboxanes and increase the production of prostacyclins, which together decrease abnormal platelet aggregation.11 A high potency of Vitamin E — 400 IU’s — is included in six tablets of HEART SCIENCE in the natural d-alpha succinate form, recognized by scientific researchers to be the most absorbable form!
  • • Selenium is an important mineral which has only recently gained attention. When incorporated into the enzyme Glutathione Peroxidase, it has highly powerful free radical-scavenging abilities, and has been shown to work synergistically with Vitamins A, C, and E. An essential mineral, Selenium used to be derived from eating foods grown in Selenium-rich soil. However, modern agricultural practices have depleted soil of its natural Selenium content, leaving many Americans deficient in this vital nutrient. Several epidemiological studies show that the incidence of advanced fatty deposits in blood vessels is much greater in individuals living in geographic areas of the United States and other parts of the world where the Selenium content of the soil is very low.27
  • Proanthodyn,™ an extract of grape seeds, is being called the most powerful antioxidant yet discovered. This highly potent, water-soluble bioflavonoid contains between 93-95% proanthocyanidins, the highest concentration of any nutrient available today. The protective actions of proanthocyanidins may help to prevent the development of plaque in artery walls by inhibiting the free radicals which are produced during the oxidation of cholesterol. The optimal daily amount (100 mg) of Proanthodyn is included in six tablets of HEART SCIENCE. In addition to the protective actions of antioxidants, several other nutrients can contribute to healthier cholesterol ratios.
  • • Chromium is a trace mineral which functions to aid the entrance of glucose into cells. Six tablets of HEART SCIENCE provide 300 mcg of Chromium in the form of Chromate® Chromium Polynicotinate and Chromium Picolinate — the most bioactive forms of Chromium. Not many people are familiar with the vital role Copper plays in the body. This trace mineral is found in all tissues of the body, and is particularly concentrated in the heart. Copper is part of several enzymes, and, in this capacity, is necessary for the development and maintenance of the cardiovascular system, including the heart, arteries, and other blood vessels. Because of its role in elastin production, Copper deficiency can severely damage blood vessels and heart tissue. In fact, researchers have found an inverse relationship between Copper status and increased risk for heart damage.10
  • • L-Proline and L-Lysine are two natural amino acids which show exciting promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL called apoprotein (a) which is believed to be a main culprit in plaque development. 17 Scientific investigation has revealed that the lipoprotein (a) particle has an adhesive quality that makes the lipoprotein fat globule stick inside blood vessels. The sticky fat globules accumulate, leading to fatty deposits in blood vessels and the subsequent clogging of the arteries. L-Proline and L-Lysine tend to form a barrierlike layer around the apoprotein (a) particle, helping to push it away from the blood vessel wall, and impeding deposit.21

    The Regulating Trio

    Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

  • • Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

    Artery Lining Protectors

    Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

    Capillary Strengtheners

    Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

    Heart Smarts

    The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

    Source Naturals HEART SCIENCE™


    The Five Tiered Approach to Heart Health
    Six tablets contain:
    Vitamins and Minerals %USRDA
    Pro-Vit A (Beta Carotene) 45,000 IU 900%
    Vit B1 (Thiamine) 50 mg 3333%
    Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
    Vit B6 (Pyridoxine HCl) 25 mg 1250%
    Coenzyme B6 (Pyridoxal-5-Phosphate)
    25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
    Vit B12 (Cyanocobalamin) 500 mcg 8333%
    Folic Acid 800 mcg 200%
    Vit C (Magnesium Ascorbate) 1500 mg 2500%
    Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
    Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
    Copper (Sebacate) 750 mcg 37.5%
    Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
    Potassium (Citrate) 99 mg *
    Selenium (L-Selenomethionine) 200 mcg *
    Silicon (From 400 mg of Horsetail Extract) 13mg *
    * U.S. RDA not established.
    Other Ingredients and Herbs
    Coenzyme Q10 (Ubiquinone) 60 mg
    L-Carnitine (L-Tartrate) 500 mg
    Hawthorn Berry Extract 400 mg
    Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
    L-Proline 500 mg
    L-Lysine (HCl) 500 mg
    NAG™ (N-Acetyl Glucosamine) 500 mg
    Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
    Taurine (Magnesium Taurinate) 500 mg
    Horsetail Extract (Yielding 31 mg of Silica) 400 mg
    Inositol (Hexanicotinate) 50 mg

    Reference:
    1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
    2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
    3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
    4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
    5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
    6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
    7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
    8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
    9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
    10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
    11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
    12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
    13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
    14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
    15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
    16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
    17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
    18. Mortensen, S.A.et al. (1985). “Long-term Coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
    19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
    20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
    21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
    22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
    23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
    24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
    25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
    26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
    27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
    28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
    29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
    30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
    31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
    32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
    33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
    34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
    35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.



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    HEART RESPONSE - Comprehensive Support for a Healthy Heart!
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    Date: June 02, 2005 11:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HEART RESPONSE - Comprehensive Support for a Healthy Heart!

    Heart Response 60ct

    Today’s modern lifestyle, filled with stress, pollution, overprocessed and fatty foods, and lack of exercise, places great strains on the cardiovascular system. Source Naturals HEART RESPONSE is a broad-range formula that supports cardiovascular health, especially heart muscle contraction, healthy circulation and the generation of cellular energy.

    HEART RESPONSE features clinical potencies of the renowned heart botanical, hawthorn, and significant amounts of the energy nutrients, Coenzyme Q10 and carnitine, along with additional nutrients and herbs. Each daily use supplies 600 mg of hawthorn, the same amount used in recent research.

    Supports Heart Health

    HEART RESPONSE was formulated to include key nutrients and herbs known to support the cardiovascular system.

    Hawthorn: Hawthorn, a rich source of flavonoids and procyanidins, has been used traditionally all over the world as a strengthening circulatory and heart tonic.

    Modern research has documented that hawthorn increases coronary blood flow and strengthens the contraction of heart muscle. Hawthorn is also an antioxidant, which scavenges and neutralizes destructive free radicals. It is only when cholesterol is oxidized that it impacts the integrity of arteries.

    Coenzyme Q10: HEART RESPONSE supplies 60 mg daily of CoQ10, a key enzyme in the Electron Transport Chain, the pathway that generates 90% of the ATP “energy currency” needed by the body. Heart muscle requires huge amounts of energy to perform efficiently—it beats more than 100,000 times each day, pumping more than 1,000 gallons of blood through the body. The heart utilizes ATP as an energy source for muscular contraction. CoQ10 also is a fat-soluble antioxidant.

    L-Carnitine: Carnitine is an amino acid-derived substance that supports heart muscle metabolism. Carnitine is needed to carry long chain fatty acids into the cell mitochondria, where they undergo oxidation to generate energy. The heart utilizes fatty acids as a preferred energy source for its metabolism.

    HEART RESPONSE delivers 300 mg per day of carntine. Taurine and Magnesium: Magnesium and taurine work closely together in the body to help maintain the normal electrical rhythm of the heart. Taurine comprises more than 50% of the free amino acid pool in our hearts, and has many electrophysiological effects on cardiac muscle cells. Alterations in magnesium levels can have profound effects on the heart. Magnesium is involved in autonomic control of the heart through several mechanisms. Bromelain: Bromelain is an enzyme mixture prepared from pineapple stems. Pineapple has been used for its health benefits for more than 500 years.

    Grape Seed Extract: Grape seed is a source of procyanidins. These plant constituents are strong antioxidants that inhibit lipid peroxidation and scavenge free radicals. In vitro studies have demonstrated that procyanidins support the integrity of connective tissue. Garlic: The use of garlic for its health benefits predates written history. Garlic’s volatile oil includes sulfur-containing compounds such as allicin, which are considered to be important biological constituents.

    Selenium: Selenium is an essential trace mineral that is necessary for the activity of the important antioxidant glutathione. Antioxidants are crucial for protecting cholesterol from oxidation, which in turn helps to maintain healthy blood vessels. B-Vitamins: Preventing an undesirable buildup of homocysteine levels may help support the integrity of arteries. Vitamins B-6, B-12 and folic acid are critical to the regulation of homocysteine levels.

    You can count on Source Naturals’ expert formulators to bring you a product based on the most up-to-date nutritional research. HEART RESPONSE combines traditional botanicals and cutting-edge nutrients, scientifically formulated to deal with many aspects of cardiovascular health. It is available in bottles of 30, 60 and 90 tablets.

    References
    Heinicke, R.M. et al. 1972. Effect of bromelain (ananase) … Experientia. 28(7):844-5. Karpati, G. et al. 1975. The syndrome of carnitine deficiency. Neurology. 25:16-24. Schmidt, U. et al. 1994. Efficacy of the Hawthorn (Cratageus) preparation L1 132 … Phytomedicine. 1:17-24. Upton, R. ed. Hawthorn Leaf with Flower – Cratageus spp. Santa Cruz: American Herbal Pharmacopoeia, 1999.



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    Fibro Response - Feel your Vitality ...
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    Date: June 02, 2005 09:56 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Fibro Response - Feel your Vitality ...

    Fibro Response

    Millions of Americans, the majority of them women, are looking for a product to soothe muscles, relieve joints, support energy, and assist the liver’s natural detoxification process. Source Naturals FIBRO-RESPONSE is based on recent research into the physiological mechanisms involved in muscular metabolism. This research has given new hope to millions of people.

    Fibro-Response: A Bio-Aligned Formulation™ FIBRO-RESPONSE is the latest in a series of formulas we refer to as Bio- Aligned Formulations. We evaluate the underlying causes of system imbalances, then design products that support alignment and harmony in your body’s interdependent systems and functions. These formulas provide targeted nutrition to help create Body Systems in Harmony™.

    FIBRO-RESPONSE was designed to help bring harmony to the interdependent systems and functions that influence joint and muscle health. Our muscles need energy and oxygen to prevent them from becoming fatigued. FIBRO-RESPONSE soothes muscles and joints by supporting oxygen supply and energy production, provides powerful antioxidants for healthy joints and connective tissue, assists healthy liver function, and supports the nervous system and circulation. The ingredients were carefully selected to influence a range of body systems. Some were included for their combined effects with other ingredients; some play important roles in more than one body system.

    Muscles and Energy Production: Our muscle cells are powered by adenosine triphosphate (ATP), a compound popularly referred to as “the energy molecule.” ATP supplies energy for all the body’s myriad physiological processes. To provide this chemical energy, the body generates and uses an amazing two to three pounds of ATP every day! ATP production occurs through a series of complex chemical reactions, including the Krebs cycle and the electron transport chain—and these energy production systems in turn require sufficient nutrients. Malic acid, a natural fruit acid that is also produced in our cells, and the essential mineral magnesium, are critical components of the energy production cycle in muscle cells. FIBRO-RESPONSE supplies both in the amounts used in recent scientific research. Additional ingredients that support energy production include coenzyme Q10, a coenzyme in the energy- producing pathways; manganese, which activates many metabolic enzymes; and copper, an important component of energy-producing enzymes. Pantothenic acid, and alpha-lipoic acid help form coenzyme A, a primary starting material for ATP production (pantothenic acid also supports the adrenal glands). Vitamins B-1, B-2, niacin and B-6 are all required for energy production.

    Connective Tissue: Healthy connective tissue is essential for proper muscle function. MSM dietary sulfur supports the integrity of connective tissue and joints. MSM is included in FIBRO-RESPONSE in the amount used in recent joint health studies. Vitamins A and C, zinc, manganese, and copper all have important roles in supporting connective tissue. Liver Support: The liver is the largest and one of the most important body organs. Its vital functions include clearing the blood of toxins, and producing bile, which aids in fat digestion and carries waste products away from the liver. Liver detoxification is essential for muscle and joint comfort. Silymarin from milk thistle seeds is an important contributor to the support of healthy liver function. N-acetyl cysteine serves as a precursor to glutathione, a critical selenium-containing antioxidant produced in the liver, which binds to toxins to help remove them from the body. Alpha-lipoic acid and Coenzyme Q10 play important roles in supporting liver health. This is partly because they are components of the body’s energy production process, and the liver demands a great deal of energy. FIBRORESPONSE also contains a classic Chinese herbal combination traditionally used to harmonize liver “chi” or “energy”: bupleurum, ginseng, pinellia, skullcap, ginger, cinnamon, and licorice. Their actions are complemented by the traditional Western herb dandelion.

    Antioxidant Support: Antioxidants protect tissues and joints from highly destructive molecules called free radicals. Alpha-lipoic acid, termed the “ideal antioxidant,” complements the antioxidant activity of beta carotene and Coenzyme Q10. Nacetyl cysteine, best known for supporting the liver, is also highly valued as an antoxidant. Zinc, selenium and copper support our natural defenses. Together, they provide a full armory of powerful antioxidants for joints and connective tissue.

    Nervous System Support: Ginkgo biloba is renowned for promoting blood flow to the brain. This is crucial, since brain tissue is very metabolically active, accounting for 2% of our body weight, yet using 15% of our total energy supply. GABA is an inhibitory neurotransmitter that may regulate the nervous system and support clear focus. The herb skullcap, and vitamin B-6, add further support.

    Taking Back Your Life: A Strategy for WellnessSM

    Source Naturals’ expert formulators have created an experiential product that can make a difference in the way you feel. But supplementation is only part of the picture. Healthy lifestyle habits can redefine and empower your own strategy for wellness.

    Rest and Relaxation. Deep, uninterrupted sleep is essential for energy and a healthy nervous system. Sleep 8 to 10 hours nightly and aim to finish meals two hours before retiring.

    Exercise. Even if you feel exhausted and it hurts to move your muscles, you must keep moving. Start easy with nonimpact movement—yoga is an excellent beginning. Do some gentle stretches, followed by 5 to 10 minutes of blood-pumping activity (i.e. biking, stair-stepping, or dancing). Listen to your body: increase activity time only when it feels comfortable. Food and Nutrition. You’ve heard it before but now it’s time to pay attention: eat healthy. Avoid spicy, oily foods and choose light, mild alternatives. Go easy on sugar and incorporate whole grains into your diet. Enjoy steamed vegetables, alternate brown and white rice, and eat less red meat and more fish or soy. Reduce or eliminate milk products. Relax and take time to chew. And drink LOTS of water—it is essential for hydrating the body, flushing out wastes, and absorbing nutrients.

    Breathing. Many people hold their breath unintentionally, often as a result of stress or anxiety. This can become a habit, reducing blood oxygen, interrupting the pumping mechanism of the diaphragm that helps circulation, and causing muscles to become tense. Breathe deeply and feel your lungs expand and fill. Notice how different you feel.

    You have in your hand a powerful, comprehensive formula. Combined with a healthy lifestyle FIBRO-RESPONSE can help you make lasting changes that will empower you throughout life.

    FIBRO-RESPONSE is available in bottles of 45, 90 and 180 tablets.

    References Abraham, G. and J. Flechas. 1992. J. Nutritional Medicine (3): 49-59. American Medical Association, Encyclopedia of Medicine. New York: Random House, 1989. Garfinkel, L. and D. 1985. Magnesium (4): 60-72. Russell, I.J. et al. 1995. J. Rheumatology 22(5): 953-8.

    Targeted Nutrition Muscle Cell Metabolism Malic Acid, Magnesium, CoQ10, Vitamin B-1, (ATP Production) Vitamin B-2, Vitamin B-3, Vitamin B-6, Manganese, Pantothenic Acid, Copper, alpha-Lipoic Acid. Connective Tissue MSM, Vitamin A, Vitamin C, Zinc, Manganese, Copper Liver Silymarin from Milk Thistle, N-Acetyl Cysteine, Ginkgo Biloba, Dandelion Root, Chinese Liver Blend (Bupleurum, Skullcap, Panax Ginseng, Pinellia Root, Ginger, Cinnamon, Licorice Root) Antioxidant Support N-Acetyl Cysteine, alpha-Lipoic Acid, Beta Carotene, CoQ10, Zinc, Selenium, Copper, Nervous System GABA, Skullcap, Ginkgo Biloba, Vitamin B-6.



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    Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement
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    Date: June 01, 2005 01:13 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement

    Elan Vital Multiple

    What makes ÉLAN VITÀL unique is its unprecedented range of nutriments in high potencies and superior forms. Quite simply, it stands alone among multiples: a quantum leap beyond maintenance...into excellence. Not only does it offer unparalleled antioxidant nutrition and a full-spectrum of essential vitamins and minerals, ÉLAN VITÀL is also formulated with specific nutrients that support:

  • • structural integrity
  • • energy generation
  • • neurotransmitter production
  • • liver health ÉLAN VITÀL brings you the very best from all areas of advanced nutrition for a difference you can feel.

    Today’s inflated levels of stress and pollution give rise to harmful free radicals – unpaired electrons that can damage living cells and compromise the proper function of tissues and organs. Antioxidants serve to protect the body by neutralizing free radicals; in fact, many scientists believe that high levels of antioxidants may prolong the effective working life span of the body’s cells. The primary strategy of ÉLAN VITÀL is to provide a wide range of antioxidants at exceptional levels, from both botanical and biochemical sources.

    Plantioxidant Protection

    ÉLAN VITÀL has the powerful advantage of Plantioxidants™, standardized botanical extracts with unparalleled free radical-scavenging properties. Plantioxidants have the unique quality of providing targeted protection because they tend to be attracted to different organs in the body. Grape Seed extract is rich in potent proanthocyanidins, a special class of highly bioavailable, water-soluble bioflavonoids that have the unique ability to cross the blood-brain barrier where they support the health of brain cells. Proanthocyanidins have been shown to efficiently scavenge oxygen radicals, as well as optimize the transport of vitamin C. They also have an affinity for collagen and elastin, the structural proteins that are abundant in vessel linings and other connective tissue. ÉLAN VITÀL contains the most concentrated extract of Bilberry available, with at least 25% anthocyanosides – compounds which are similar to proanthocyanidins but with an unusually strong attraction to optical tissue. They have been shown to protect cellular integrity in the delicate structures of the eyes. Ginkgo biloba extract is a standardized concentration of prime quality ginkgo leaves, yielding 24% ginkgoflavoneglycosides. These active compounds are potent antioxidants that have been associated with superior oxygen transport throughout the body with a special affinity for brain capillaries. Silymarin is the name given to a complex of three bioflavonoid-like compounds — silybum, silycristin, and silymarin — extracted and concentrated from milk thistle seeds. Silymarin functions in the body as an antioxidant with a special attraction for the liver. It has been researched and used extensively in Europe, where it is prized for its unique ability to nourish the liver and support its natural regeneration process by speeding up DNA synthesis in liver cells. Quercetin is a bioflavonoid present in some foods, such as onions and blue-green algae. A cousin of rutin, quercetin has been shown to stabilize cell membranes and help prevent free radical damage to this vital but vulnerable part of cells. Bioflavonoids and related compounds do their best antioxidant work when in the presence of Vitamin C, the nutrient they are most often paired with in nature. The vitamin C provided in ÉLAN VITÀL is both water- and fat-soluble. This combination is crucial because the tissues and membranes richest in fatty acids are most at risk to free radical attack. Fat-soluble vitamin C in the form of ascorbyl palmitate has an affinity for these highly vulnerable structures.

    Antioxidant Nutrients

    ÉLAN VITÀL not only provides botanical defense plants to combat free radicals, but also contains tried-and-true antioxidant nutrients: Biochemicals known as vitamins, minerals, and amino acids work together for maximum protection to all the body’s cells. The amino acid, N-Acetyl Cysteine, is a powerful and highly versatile antioxidant that doubles as a precursor to glutathione and glutathione peroxidase, two of the most formidable cell-protective compounds manufactured by the body. Studies have shown that supplemental N-acetyl cysteine enhances internal levels of glutathione far better than supplements of glutathione itself. Methionine also contributes to the synthesis of glutathione, and is an efficient transporter of certain antioxidant minerals, magnifying their activity. Vitamin A is included in both its fat-soluble palmitate form and in its provitamin form, Beta Carotene. While preformed A has long been known to play a role in the body’s defenses, beta carotene itself has recently been shown to possess a powerful ability to scavenge free radicals and contribute to the youthful function of some tissues. Vitamin E is one of the most important antioxidant compounds in nature. It works to prevent harmful oxidation within each cell and is vital in the protection of red blood cells from free radical-induced rupture. Selenium is an extremely powerful antioxidant shown in studies to work synergistically with Vitamins A, C, and E. In combination with cysteine, selenium helps build the glutathione peroxidase molecule. ÉLAN VITÀL offers a 50/50 blend of the two most scientifically supported forms of selenium: L-selenomethionine and sodium selenite. In addition to being an antioxidant itself, Zinc works closely with fat-soluble vitamin A by facilitating its release from the liver to the rest of the body. In ÉLAN VITÀL, Zinc is synergistically bound to methionine for optimal bioavailability. Copper sebacate is a natural compound that can function as the copper-SOD antioxidant system in the body, one of the first lines of defense against free radical attack. Copper sebacate is a highly absorbable form that possesses significant free radical scavenging activity.

    Supporting Structural Integrity

    An important adjunct to antioxidant nutrition is the amino sugar N-Acetyl Glucosamine, or N-A-G™. Amino sugars are essential components of cell membranes and their surface structures, as well as of the “ground substance” that holds body tissues together. They are also a key constituent of the synovial fluid in the joints. Recent research has revealed that amino sugars play an important role in maintaining the integrity of the connective and structural tissues of the body, a property that complements perfectly the actions of antioxidants: where antioxidants may prevent damage from occurring, amino sugars may help the body repair and regenerate damaged tissue. N-A-G’s activity is supported in ÉLAN VITÀL by other nutrients helpful to structural tissue. The mineral Manganese is required for building amino sugars into mucopolysaccharides, the large molecules that make up the ground substance that holds cells together. Choline and Inositol are both components of phospholipids, principal constituents in cell membranes. Two B vitamins, Folic Acid and Vitamin B12, are important to cell regeneration and to the development of healthy red blood cells.

    Enhanced Energy to Maximize Metabolism

    ÉLAN VITÀL is a potent source of coenzymes, metalloenzymes, and metabolites involved in energy production in the body. There are two main energy production cycles in the cells: the glycolytic cycle and the Krebs’ cycle. Together, they generate about 90-95% of the body’s entire energy supply – using fats, sugars, and amino acids as fuel, with enzymes as facilitators. The enzymes which catalyze energy production function in combination with coenzymes made from vitamins such as B1, B2, B3, B5 and Biotin, plus metalloenzymes made from minerals, including Magnesium, Manganese, and Copper. Biotin, an often overlooked nutrient, may function to help the body maintain a youthful metabolism. The mineral Magnesium aids in energy production, not only by acting as a cofactor to some enzymes, but also as a stabilizer of ATP, the body’s primary energy molecule. Some of the key connecting enzymes in the energy production process require two additional non-vitamin coenzyme nutrients to maximally convert food into energy: Lipoic Acid and Coenzyme Q10. Lipoic acid helps convert the end-product of the glycolytic cycle, pyruvate, into acetyl-CoA, a principal fuel for the higher energy Krebs’ cycle. Coenzyme Q10. is the connecting link for three of the four main enzyme complexes in the Electron Transport System, an off-shoot of the Krebs’ cycle, where ATP molecules are “cashed in” for energy. The muscle-supporting electrolyte mineral Potassium is in the form of Alpha- Ketoglutarate, a critical Krebs’ cycle metabolite that has additional benefits. It has long been used to improve the efficiency of ammonia-clearance from the body, an indispensable function, as ammonia is both exceedingly harmful and constantly produced through the natural metabolism of proteins. Because alpha-ketoglutarate is an organic compound well-recognized by the cells, it is an excellent transporter of potassium into the cells. Succinic Acid, or succinate, is also a metabolite in the Krebs’ cycle. It not only boosts production of ATP energy potential, but also increases the muscle cells’ production of creatine phosphate, another high energy biochemical. Chromium is the essential mineral component of glucose tolerance factor, or GTF, which functions to help insulin (one of the two main blood sugar-controlling hormones in the body) draw sugar molecules from the bloodstream into the cells.

    Smart Nutrients

    ÉLAN VITÀL contains natural substances that sharpen performance beyond just the physical. N-Acetyl L-Tyrosine is a highly stable and absorbable form of the conditionally essential amino acid L-tyrosine, a precursor to the major excitatory neurotransmitters dopamine, norepinephrine, and epinephrine. DMAE is a precursor to one of the body’s main neurotransmitters, acetylcholine. From the Plantioxidants comes standardized Ginkgo biloba extract, whose compounds readily cross the blood-brain barrier where they support the integrity of the capillaries in the brain.

    Guarding the Liver

    ÉLAN VITÀL provides several nutrients which collectively support optimal liver function. This is an essential aspect of a multiple, because the liver is responsible for converting nutrients – from food as well as from supplements – into their usable forms. If liver function is compromised in any way, nutrient supplements may be rendered inert in the body. The liver is especially at risk because it must filter out ingested toxins and is continually exposed to chemicals that generate free radicals. N-Acetyl Cysteine and Silymarin have both demonstrated a strong affinity for the liver. Nacetyl cysteine contributes to increased levels of glutathione and glutathione peroxidase, both of which the liver uses in its natural cleansing function. Silymarin provides unparalleled support to the liver’s natural regeneration process. Because of its many vital functions, the liver uses as much as 12% of the body’s energy supply, even though it represents only 3% of body weight. The liver therefore uses a greater proportion of energy nutrients, especially Coenzyme Q10 and Lipoic Acid. Both are highly concentrated in the liver; and lipoic acid in particular has been researched and used heavily in Europe where it is prized for its special protective actions in the liver. Ascorbyl Palmitate is a fat-soluble form of Vitamin C, meaning it can provide antioxidant protection for fatty tissue. This is especially valuable to the liver, which tends to develop fatty streaks that are most vulnerable to damage. Vitamin E has been researched extensively for its antioxidant properties with regard to the liver.

    The Multiple for the 21st Century

    ÉLAN VITÀL is truly a one-of-a-kind multinutrient supplement: one that leaves no nutritional stone unturned. Based on the biochemical principles of nutrition and metabolism – in context of today’s challenges to our health – ÉLAN VITÀL approaches optimal nutrition from several directions...all leading to a lifetime of health and vitality.



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    COENZYME Q10 - Transforming food into energy
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    Date: June 01, 2005 11:06 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Coenzyme Q10 - Transforming food into energy

    Coenzyme Q10

    It’s 3:30 p.m. and you feel irritable; you can’t seem to concentrate. You were so busy you skipped lunch. At last you bite into the sandwich that you were ready for 3 hours ago. By the time you have eaten half of it, energy is starting to flow through you. What happened? The answer to that question is both extremely complex and very simple. In essence, your body transformed the food into useable energy. CoQ10 is a crucial component of the primary energy generating cycle that takes place in each of the trillions of cells in our bodies. CoQ10 is essential for human life.

    To transform that lunchtime sandwich into useable energy your body essentially has to burn it - just the way a car burns gasoline to drive its engine. This energy generating process takes place in structures called mitochondria - tiny power plants which are within every cell. Inside these energy generating stations, fats, sugars, and amino acids are transformed into ATP, an energy-rich molecule sometimes called the “energy currency” of the body.

    Energy Generation Requires Nutrients

    The body requires many nutrients in order to perform the complex biochemical processes that convert food into ATP “energy currency.” Some of these nutrients such as the B-vitamins are familiar to us. However, there are many other substances which are essential to this process. Coenzyme Q10 is one of these.

    Functions of CoQ10

    Several complex metabolic pathways are required in order for the body to transform that lunchtime sandwich into energy that you can feel and use. First glycolysis and the Krebs’ cycle break down large molecules of protein, carbohydrate and fat into smaller components. CoQ10 is a key enzyme in the Electron Transport Chain - the final stage in this extraordinary design. This pathway generates 90% of the ATP needed by the body from the food we eat. ATP provides the “energy currency” for the following crucial metabolic functions: 1) synthesis of cellular components including cholesterol and proteins (formed primarily by the liver), 2) nerve conduction (in the brain and peripheral nerves), and 3) energy for muscular contraction (of the heart and skeletal muscles). The Heart: The heart muscle (myocardium) consumes a tremendous amount of energy. Your heart beats over 100,000 times and pumps 1,000 gallons of blood each day! CoQ10 is necessary for the generation of the energy required by the heart. Numerous scientific studies have demonstrated that supplementation with this nutrient may support normal heart function. Its presence is necessary for cardiac performance during exercise as exemplified by criteria including: blood flow, oxygen utilization, contractility and exercise tolerance. In addition, CoQ10 may play a role in the regulation of blood pressure. The Gums: Since the 1970’s scientists have been researching the effects of CoQ10 on the health of the oral tissues. Although the mechanism of action is not known, research has established that CoQ10 has a profound ability to preserve and maintain the health of the gums. Antioxidant Properties: CoQ10 plays an additional vital role in our metabolism as a protector of lipids in cell membranes. Laboratory studies have also shown that CoQ10 is more efficient than vitamin E, beta carotene or lycopene in safeguarding LDL cholesterol from oxidation by peroxides. This process is important for maintaining the health of our blood vessels.

    Energy Insurance

    CoQ10 is needed in body tissues where energy production is critical, such as the liver, brain and muscles. Therefore we include CoQ10 in significant potencies in many of our premium formulas, such as Life Force Multiple™, Élan Vitàl™, Heart Science™, Liver Guard™, MenoBalance™, Higher Mind™, MegaMind™ and Wellness Multiple™. We also offer a combination of CoQ10 and Lipoic Acid (30 mg each), CoQ10 Sublingual (30 mg and 60 mg), 30 mg CoQ10 Softgels with Bioperine® and 30 mg CoQ10 NutraSpray™. Our single CoQ10 products are CoQ10 in 15 mg, 30 mg, 75 mg, 100 mg, and Ultra Potency 125 mg caps.

    References
    1) Folkers et al., BCACQ, Elsevier, 1977
    2) Judy et al., BCACQ, Elsevier, 1984.
    3) Kamikawa, T. et al., American Journal of Cardiology, Vol. 56, August 1, 1985, p. 247-250.
    4) Nohara et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1984.
    5) Packer, L., Oxidative Stress and Aging, Birkhauser Verlad, 1995.
    6) Stocker, et al., Proceedings of the National Academy of Sciences, Vol. 88, pp 1646-1650, March 1991.
    7) Tortora, G. Principles of Human Anatomy, 4th Ed., Harper & Row, New York, 1986, p. 301.
    8) Wilkinson and Arnold, Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.
    9) Yamagami et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.



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    Date: May 09, 2005 06:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    It's in the Blood

    Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

    The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

    “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

    “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

    At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

    While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of Coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

    Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

    And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

    Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

    King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

    Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

    "Blur of Products"

    With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

    To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

    Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

    Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

    Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

    “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

    On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

    Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

    Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

    Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

    Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

    Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

    Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

    “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

    Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

    Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

    “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

    For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

    Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

    Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

    Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

    Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

    Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

    “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

    Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

    Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

    However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

    Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

    Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

    Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

    New Weapons

    There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

    With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

    Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

    “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

    Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/

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