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Search Term: " Supplemenal "
What is DMAE and Why is it Important?   
Date:
October 10, 2022 04:25 PM
DMAE (Dimethylaminoethanol) is an amino alcohol that is normally found in minute quantities in the brain. It is generally regarded as a precursor to the essential nutrient choline, which is needed for the brain to produce acetylcholine, a neurotransmitter involved in nerve signal transmission and healthy brain function.* So what does that mean for you and your health? Let's take a closer look. DMAE has been shown to have a positive effect on cognitive function and memory, which is why it's often referred to as "the memory vitamin." In one study, supplemented with DMAE showed significantly improved verbal skills and memory recall compared to those who did not take the supplement. Supplemental DMAE has also been shown to improve focus and reduce mental fatigue. In addition to its cognitive benefits, DMAE has also been shown to have anti-inflammatory and antioxidant effects. Inflammation is linked to a number of chronic diseases, so reducing inflammation can lead to better overall health. The antioxidant effects of DMAE may help protect cells from damage caused by free radicals. In Summary: DMAE is a nutrient that is normally found in minute quantities in the brain. It plays a crucial role in cognitive function and memory recall, and has also been shown to have anti-inflammatory and antioxidant effects. If you're looking for a way to improve your cognitive function, memory, focus, or overall health, consider adding DMAE to your diet. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6497) Trace minerals from deep in the ocean found to increase blood flowand reduce inflammation in the brain 
Date:
April 17, 2019 01:26 PM
Those who follow paleobiology have a deep belief that life started within the ocean itself. Right now, those who are highly active in physical activity typically rely on supplemental beverages that include a large amount of essential vitamins and minerals, but they often include a lot of preservatives as well. Fortunately, a recent study showed that athletes are able to thrive and preform just as well when ingesting discovery of deep ocean minerals (DOMs) through natural avenues. Key Takeaways:
"From this idea, scientists hypothesized that ingesting the minerals from deep ocean water may replenish incomplete molecular complexities and increase our physical capacity against energy-consuming and physically taxing challenges." Read more: https://www.naturalnews.com/2019-02-11-trace-minerals-from-ocean-increase-blood-flow-reduce-inflammation.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6136) Supplemental nutrition found to treat brain injury better than prescriptions, and may even provide some protection against injury
Date:
July 26, 2018 08:58 AM
Researchers from Texas Christian Univeristy recently led a research review into whether nutritional supplements can aid in recovery from Sports Related Concussions (SRC). SRCs, sometimes referred to as mild traumatic brain injuries (mTBI), are caused by biomechanical forces resulting from a direct blow to the head, face or neck. While mTBIs are harder to diagnose than other TBIs, they can become progressively more serious through repeated trauma and the brain’s inflammatory response. The research review decided that Curcumin, Creatine and Omega-3 supplements show potential for promoting recovery from SRCs, but noted that more research is needed. Key Takeaways:
"Mild traumatic brain injuries, however, are not as easily detected as that of a severe TBI. The authors noted that while sports-related concussive and sub-concussive impacts start out as mild, the brain’s inflammatory response to an injury may aggravate it, especially in repeated and prolonged exposures." Read more: https://www.naturalnews.com/2018-07-23-supplemental-nutrition-found-to-treat-brain-injury-better-than-prescriptions.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5677) 5 ways to relieve period cramps naturally
Date:
July 16, 2017 12:14 PM
For most women, there is a cyclical monthly occasion that consumes their bodies with pain and cramping. While some deal with this pharmacologically, there might be natural alternatives to menstrual symptoms. A recent article on foxnews.com provided several tips that may help relieve menstrual symptoms without turning to pills. The following recommendations were made: Fish oil and Vitamin B12 supplementation, increasing vegetable intake while reducing fats, Magnesium supplementation, exercise, and heat therapy. Of course, this article did recommend seeking a physicians advice before implementing any of these dietary or excercise recommendations. Key Takeaways:
"... what if you could relieve period cramps naturally? Some of these remedies might even help you conquer the cramps once and for all." Read more: http://www.foxnews.com/health/2017/07/10/5-ways-to-relieve-period-cramps-naturally.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4984) Vitamin C is a powerful heart healer, especially after surgery
Date:
February 13, 2017 01:19 PM
Vitamin C has long been known to have healing properties. It boosts the immune system. We are told to use it when we're having a cold or other illness. It is apparently also good for healing the heart. Surgery can be hard on the heart and vitamin C is helpful at this time. Key Takeaways:
"A new study, published in the journal BMC Cardiovascular Disorders, found that oral administration of supplemental vitamin C after heart surgery could slash the risk of AF by up to 73 percent in high-risk patients, without adding side effects." Reference: //www.naturalnews.com/2017-02-10-vitamin-c-is-a-powerful-heart-healer-especially-after-surgery.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3934) The Difference Between Type I and II diabetes.
Date:
January 19, 2017 10:26 PM
There are mainly two different types of diabetes - Type 1 diabetes and Type 2 diabetes.
Type 1 diabetes is known as insulin-dependent or juvenile diabetes. It is a condition in which there is an absolute lack of insulin. Due to the attacking of the body's immune system, the beta cells which are present in the pancreas and are responsible for making and secreting insulin die. Thus, there are no cells available to make insulin. So, in this case, the body will die without getting supplemental insulin immediately or in near- immediate future. The only treatment for this diabetes is insulin shots. Almost 10% of the people get this diabetes.
Whereas in type 2 diabetes, beta cells are present therefore insulin is also present. This diabetes is also known as non-insulin dependent diabetes. Insulin production produced is less than the amount of insulin the body requires. Almost 90% get affected by this type of diabetes. Treatment includes proper diet, exercise, and pills.
Usually, type 1 diabetes starts during childhood whereas type 2 diabetes is usually diagnosed during adulthood. As type 1 diabetes affects mostly young babies and children, it is known as juvenile-onset diabetes. People who have type 1 diabetes lack total insulin whereas type 2 diabetics have too little insulin.
Even the causes of type 1 and type 2 diabetes are entirely different. It is not possible to prevent type 1 diabetes whereas type 2 can be avoided. But type 2 diabetes may be genetic also. It may be the result of obesity or high blood pressure. The symptoms of type 1 diabetes are very severe. Suddenly the child becomes feeble and sick; urination is increased, experience increased thirst, nausea, vomiting, stomach and abdominal pain, excessive fatigue, weight loss and decreased appetite. Immediate medical attention or usually hospitalization is required for the person suffering from these symptoms. On the other hand, type 2 is often diagnosed before the presence of any symptoms.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3804) Arginine and Ornithine Supplementation for Enhanced Athletic Performance
Date:
January 19, 2014 07:41 AM
Arginine and ornithine Arginine and ornithine are two amino acids that are incorporated in protein that is found in many dietary sources, such as meat, egg whites, soy or fish. Although these two amino acids can be supplied to your muscles from food sources, several research studies have examined the benefits of arginine and ornithine supplements. Fitness researchers found positive and promising results in terms of muscular growth, endurance and fatigue prevention. These supplements are especially known and popular among bodybuilders and other types of strength athletes, as it has been clearly demonstrated that they improve athletic ability on a biochemical level.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2973) Can DMAE Help Memory And Mood?
Date:
December 19, 2013 07:23 AM
Do you ever feel like you are experiencing lapses in memory or you have a low general mood? There is evidence that DMAE might be able to help with both memory and mood. DMAE occurs naturally in the human brain. When we take supplemental amounts of the compound, brain function effects can be seen. DMAE as a Supplement It is thought that the supplement works by increasing the speed of the brain's turnover and synthesis of a neurotransmitter called acetylcholine. This neurotransmitter plays a strong role in maintaining general mental ability. It also works at supporting a stable, healthy memory in older adults. It is also believed that DMAE might work by stopping choline metabolism. This allows the free choline to gather in the blood, go into the brain, and stimulate the cholinergic receptors. A French double-blind study was performed to measure how much of an impact the supplement DMAE has on both mood and vigilance. Four of the subjects were categorized as having anxiety, and four other subjects were the controls. They were each given 1200mg of DMAE over the course of 5 days. These subjects were measured daily for their EEG and convergence of the inter hemispheres of the brain. In the case of the four subjects that were given the supplement, progressive sync of the two brain hemispheres was found. This is correlated with increased neuromotor control, increased verbal memory, improvement in behavioral tasks, as well as better control of anxiety. Another use for DMAE worth mentioning is its affects on learning deficiencies like ADD or hyperkinesia. Many doctors prescribe amphetamines for conditions like this, but DMAE has also proven useful. According to studies, hyperactivity and irritability decrease, and scholastic ability improves from supplementing with DMAE. In addition to improving these conditions there is evidence that DMAE can improve life span, IQ, and motor mechanisms. It is very important to take the correct dosage of DMAE. I would start with taking 200-400mg first, and work your way up from there. Sources:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2929) Can Colostrum Help Promote Healthy Immune Function?
Date:
October 12, 2011 01:33 PM
Colostrum OverviewColostrum, also known as first milk and yes that is not a typo error, I did mean first and not fresh, is a form of milk produced by the mammary glands of mammals in late pregnancy and as my wife put it is the first milk that comes out of your breasts and as advised by our doctor was the most nutrient rich of all the breast milk she will ever produce. A woman’s breast is the one responsible for producing colostrums and start during pregnancy and continues on through the first days of breastfeeding. This special milk is thick and sticky and is more like yellow in color instead of white of dirty white color as most milk. It also is low in fat but high in carbohydrates, protein and antibodies to help build a foundation of good health for the newborn. So in other words it is the first milk that the mother produces and the first milk that the baby should ingest and must ingest because of the benefits it can bring and this makes calling it the “First Milk” all the more appropriate. Most of the mammals in the planet will generate colostrum just before giving birth. We all have heard it before, “breast milk is still best for babies”, and this holds that statement to be even more true. The milk from the mom during pregnancy given that the mom is also in good health will be filled with nutrients that will be passed on to the offspring. It is nutrients in its purest form as untainted and unprocessed food will be given to build on the blank slate that the newborn can be considered to be since it still does not have a well built defense against viruses and bacteria which brings me back to the question above.
Promoting Healthy Immune Function With ColostrumColostrum contains a whole lot of antibodies and will most definitely help protect the newborn against diseases and will also even aid in building a strong foundation of good health all throughout his life. It also will not be a problem for the newborn’s tiny underdeveloped digestive system as it is designed to be easily digested. It has laxative effects which will help alleviate the movement of waste and any excess impurities in the newborn’s system which in turn can help prevent jaundice which is a very common health issue for newborns. In so many ways it is perfectly designed for your new born it is often referred to as the perfect first food for the baby as only nature can design. It has nutrients tailored fit for the newborn and has very high concentration of immune factors that it works almost like a vaccine and to add to that it is even 100% safe, tried and tested for thousands of years. The good news is that there are supplemental colostrums available in the market today to mimic those effects to the new born, many studies have shown that colostrums immune factors are four times richer and has shown to be capable of correcting a dysfunctional immune system in adults. Supplement forms of colostrums are from bovine sources. These sources still offer health benefits to the immune system and digestive tract. You too should take colostrums even as an adult to help boost your health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2504) Essential Enzymes Feel The Body To Good Health
Date:
March 19, 2010 07:08 PM
Most American diets are lacking in enzymes. The only way to get them is from live food or else through supplements. A mostly cooked-food diet needs a larger amount of enzymes from the digestive organs. This causes exhaustion and degeneration of the organs. The stress can be taken off of the pancreas and the entire system by supplementing with digestive enzymes. There are two types of enzymes: digestive and metabolic. The digestive enzymes work in the gastrointestinal tract to break down food into forms that can be assimilated and used by the body. Digestion takes up a lot of the body’s energy and needs the help of digestive enzymes in order to properly assimilate food. Overcooked food destroys enzymes. Additionally, foods may be lacking in enzymes due to pesticides, preservatives, pasteurization, and water containing chlorine. All of these are responsible for destroying enzymes. With age, our bodies manufacture fewer enzymes. It is necessary that the body has a proper balance of amino acids in order to manufacture enzymes. Metabolic enzymes work inside the cells in order to produce energy and detoxification. This type of enzyme is required for all bodily functions. Metabolic enzymes produce the energy that is required for the body to survive and thrive. A steady supply of enzymes is needed in order for complicated chemical reactions to occur in the body. Supplemental digestive enzymes should contain protease, which is responsible for breaking down protein into amino acids. Amylase is responsible for breaking down starch into sucrose, while lipase functions in the digestion of fats. Cellulase is needed to break down cellulose. Enzymes are responsible for improving the digestion and assimilation of food. They also help to improve assimilation of vitamins, minerals, amino acids, and essential fatty acids. They also help the body break down old encrusted material on the entire digestive system. Enzymes can be taken after meals in order to improve digestion. Additional enzymes are necessary in between meals so that they are able to penetrate into tissues and break down undigested protein that can cause disease. They may also help prevent conditions like cancer, arthritis, and autoimmune diseases. Supplemental enzymes are usually needed because of poor eating habits that deplete the body of its own enzyme reserve. Eating too much cooked food, processed food, wrong food combinations, pesticides, preservatives, and additives can lead to the destruction of essential enzymes. For more information on the many beneficial effects of enzymes, please contact a representative from your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2131) Royal Jelly
Date:
June 23, 2009 11:02 AM
Royal jelly is an incredibly rich, creamy, opalescent, white liquid that is synthesized by the worker bees exclusively for the nourishment and cultivation of the queen bee. It is considered the most precious gift of the hive, as it extends the longevity of a bee’s life from six weeks to five years. Royal jelly is incomparable in its ability to enhance both physical and mental performance. Put in a simple manner, royal jelly promotes longevity by helping to maintain health, beauty, and youth. It is extremely potent, highly nutritional, and very natural. Royal jelly is extremely difficult for scientists to completely breakdown its components or synthesize its compounds. No matter how Royal Jelly is studied, certain components of the substance still seem to mystify even the most brilliant scientists. Because of this, duplicating what is thought to be the exact chemistry of royal jelly does not duplicate its effects in the human body. This means that only honeybees can make royal jelly. Royal jelly is rich in proteins and B-complex vitamins, especially pantothenic acid, which is often associated with reversing some of the major effects of aging. Although the chemical makeup of royal jelly may vary slightly according to the location it is found in, the United States Department of Agriculture has analyzed one gram of royal jelly and found in to contain vitamin B1, vitamin B2, vitamin B6, niacin, pantothenic acid, biotin, inositol, folic acid, and vitamin C. Royal jelly also contains vital fatty acids, sugars, sterols, phosphorus compounds, and acetylcholine. Acetylcholine is responsible for the proper transmission of nerve impulses and the proper functioning of the endocrine system. A lack of acetylcholine in the body can make us susceptible to a number of nerve disorders such as Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis. Royal jelly can be purchased in a pure jelly-like material that must be kept frozen or refrigerated. It is also available in capsules, tablets, soft gels, and in honey chewable. Royal jelly is at its ideal best when it is combined with other natural beehive products and complementary botanicals. Because royal jelly spoils very easy, much research has been done on the ability to preserve this key nutrient. One good way to present and preserve royal jelly is within its natural medium of pure honey. By taking freeze-dried varieties of royal jelly, one can also obtain their supplemental dose. A capsulated, freeze-dried variety is an excellent and convenient way to ingest royal jelly. It is necessary to purchase quality bee products in order to obtain the potent and pure varieties of any type of bee food or by-product. It should be noted that a relatively small percentage of the population can experience a laxative effect from royal jelly or bee pollen. Additionally, allergic reactions can happen. However, they are quite rare. Some of these allergies are due to poor quality pollen, as it has been gathered from commercially sprayed flowers or improperly cleaned, dried, or stored. Anyway taking bee products should begin slowly, in small amounts to be sure that an allergic reaction will not occur. Natural bee pollen and royal jelly can be found at VitaNet ®, LLC health food store. Always purchase name brands to ensure that you receive a high quality and pure product.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2023) L-Cysteine
Date:
May 08, 2009 10:00 AM
L-Cysteine is what is known as a non-essential amino acid, meaning that it can be biosynthesized by the body and hence not an essential part of your diet. Due to its possessing a thiol side chain, it is termed a hydrophilic amino acid with an affinity for aqueous systems. Because of this it is relatively highly reactive, and is therefore an important component of a large number of enzymes and proteins. Although, after all, it is not an essential amino acid, deficiencies can occur in the young and in the old, and also in those suffering certain metabolic diseases. Dietary sources include high-protein foods such as chicken, turkey, pork, dairy products and vegetables such as cereals, broccoli, garlic and onions. The biochemistry of this amino acid begins with another amino acid known as serine, and also methionine. The latter is fist converted to homocysteine, which is then combined with serine to form cystathionine. This is then converted into cysteine and alpha- ketobutyrate. The thiol group is highly reactive and gives cysteine its biological properties. L-Cysteine possesses strong antioxidant properties due to the thiol group which easily undergoes redox reactions. However, it is for its detoxification effect on the body that the amino acid is mainly taken as a supplement. It is, therefore, these properties that we shall discuss first. Cysteine can reduce the toxic effects of alcohol, such as a hangover or the more serious liver damage. The by-product of alcohol metabolism that does most damage and is responsible for the majority of the negative after-effects of excessive alcohol consumption is acetaldehyde. L-Cysteine converts acetaldehyde into the more acceptable acetic acid, and so prevents the aldehyde from having too much of a negative effect on your health and well-being. However, the results obtained from such studies have been from animals only, and the therapeutic effects of cysteine have not yet been tested on humans. What has been tested and is known is that L-cysteine is effective in the detoxification of heavy metals in the body. A common source of heavy metal toxicity is mercury from amalgam fillings in the teeth. Although the Environmental Protection Agency (EPA) declared in 1989 that dental amalgams are a hazardous substance under the Superfund law, many people still have them in their mouths. The thiol group and L-cysteine has a high affinity for mercury and other heavy metals, as previously stated, and a supplement can be used to remove from the body any mercury leached from mercury-based tooth fillings. It can also be used to bind to copper, lead and cadmium. Lead and cadmium are particularly toxic to the human body, and even though lead is no longer used in plumbing or paints, and cadmium in toys or paints, there are still many sources of these two heavy metals available that can lead to human toxification. An L-cysteine supplement can be used to remove these heavy metals from the body. Any proteins containing cysteine will tightly bind heavy metals such as lead, cadmium, molybdenum, cobalt and mercury, and allow them to be excreted by the body in the usual fashion. This direct involvement in heavy metal detoxification is a very useful property of this amino acid. Another detoxification application of L-cysteine is in direct involvement in protecting cellular glutathione levels, and also the prevention of the death of liver cells by acetaminophen poisoning. The latter is of particular interest to many people since acetaminophen is better known as paracetamol, and since this is a freely available over-the-counter drug, overdoses are not unknown. The result of an overdose is the necrosis of liver cells, with eventual liver failure and death. The treatment of choice is N-acetylcysteine. If used within 10 hours of the overdose it is extremely effective, and even from 16 to 24 hours it is better than other controls. It is believed that the acetylcysteine liberates cysteine which, when available to the liver, enables the biosynthesis of glutathione. Glutathione can then maintain the production of the fifth metabolite required for the specific detoxification of the paracetamol/acetaminophen. L-Cysteine is also an essential component in the biosynthesis of coenzyme A, an enzyme essential for the production of energy from fats and carbohydrates. It is also a very important component of hair, from which it is commercially produced. Without an adequate intake of L-cysteine the growth of healthy hair would not be possible. There are several supplemental uses of L-cysteine including the treatment of bronchial conditions for which the amino acid can help to liquefy and clear mucus from the airways and lungs. It is also used to protect against side effects of chemotherapy treatment of cancers and for medical treatments for excessive exposure to radiation. However, there are certain situations in which L-cysteine should be avoided when at all possible. Diabetics should not use it, and neither should those suffering from cystinuria, whereby large quantities of amino acids, including cystine, are excreted in their urine. L-cystine, incidentally, is formed by oxidation of L-cysteine. Paradoxically the amino acid is one of the several hundred additives made to tobacco by the cigarette companies. Although, as with the majority of tobacco additives, its purpose is unknown there are two possible reasons for its inclusion. L-Cysteine is a known expectorant, so it could be added to promote the expectoration of mucus in the lungs which is promoted by smoking, and it also increases the production off the antioxidant glutathione that is depleted in smokers. There are several other non-medical uses for the amino acid, but it is for is its detoxification properties that it is most used as a supplement. However, because it is largely derived from human hair or duck feathers, it may not be classed as kosher or halal in spite of many claims made to that effect, though the more expensive source of microbial fermentation from corn sugar can be. The substance is recognized as safe by the FDA, and must be labeled as L-cysteine when it is present in a preparation intended for its therapeutic effects. Keep in mind however, that it should be avoided by diabetics.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2005) Detoxify With L-Citrulline
Date:
April 13, 2009 03:51 PM
L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood. It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea. The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea. The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-hydroxyarginine, and then into L-citrulline with the release of nitric oxide. So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells. Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred. In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure. Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery. During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow. It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels. It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid? Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise. Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted. Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.
L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1993) Lutein 20mg (FloraGlo)
Date:
September 26, 2008 03:49 PM
Maintains Healthy Visual Function* It has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the first four weeks of the study, plasma levels increased five-fold from pre-supplement measures, and then remained at this level for the duration of the study. It was also shown that, due to increased deposition of lutein in optical tissues, macular pigment density increased by an average of 5.3% at the 4-week mark, and continued to increase until the duration of the study.1 A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids might play a protective role in supporting the maintenance of healthy vision.2 The Age-Related Eye Disease Study (AREDS) was a landmark study of the effects of diet and antioxidant supplementation on eye health. The study enrolled over 3500 subjects aged 55 to 80 years who were followed for approximately 6 years. Among the data collected in this multi-faceted study was a self-administered Food Frequency Questionnaire (FFQ). The AREDS Report No. 22 examined the data from the FFQs and determined that, of the nutrients evaluated, only lutein and zeaxanthin were directly related to maintaining eye health with statistical significance3. These findings corroborated similar results of an earlier multi-center study published in the Journal of the American Medical Association that also found that those with a higher intake of lutein and zeaxanthin maintained healthier eye function.4 These promising results have spurred the design of a second major clinical trial (AREDS2), which is currently enrolling participants to study the impact of supplemental xanthophylls (FloraGLO® Lutein and zeaxanthin) and other nutrients on age-related eye health.5 In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were divided into three groups and received either 10 mg FloraGLO® lutein, 10 mg FloraGLO® lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the FloraGLO® lutein and FloraGLO® lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group.6 These results demonstrate FloraGLO® lutein’s beneficial effect on maintaining healthy visual function. Newly published research has demonstrated that lutein and zeaxanthin supplementation may enhance visual performance under glare conditions. Forty healthy subjects took daily doses of 10 mg FloraGLO® Lutein plus 2 mg zeaxanthin for six months. They were evaluated for changes in macular pigment, glare disability and photostress recovery at the onset of the study, and at 1, 2, 4 and six months. After six months, subjects experienced an average increase in macular pigment optical density (MPOD) of 39% compared to baseline, and all but two participants experienced some increase in MPOD. This increase in MPOD was also directly related to measured improvements in visual performance after exposure to bright light, as well as photostress recovery.7 This study suggests another way in which lutein and zeaxanthin can help support optimal visual function in healthy individuals. Potent Antioxidant Protection* Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species.8 More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol9 demonstrating its potential as a high-powered antioxidant. A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems.10 Supports Healthy Skin* A recent randomized, double blind, placebo-controlled study has demonstrated the positive effects of oral and topical administration of lutein on skin health parameters (surface lipids, hydration, photoprotective activity, skin elasticity and skin lipid peroxidation). Forty female subjects were divided into four treatment groups. Treatment options included oral administration of 5 mg of FloraGLO® Lutein twice daily or placebo and topical administration of 50 ppm FloraGLO® Lutein twice daily or placebo. Each treatment group received either an active oral treatment with a placebo topical treatment, a placebo oral treatment with an active topical treatment, both active treatments, or both placebo treatments. Statistically significant improvements were seen in all five parameters tested in all treatment groups compared to the group receiving only placebos. The greatest overall improvements were seen in the group receiving both active oral and topical treatments, while lesser but still significant improvement was seen in both the active oral only and the active topical only groups. Additionally, oral administration of lutein conferred superior photoprotective activity (as measured by skin surface redness after exposure to ultraviolet light) and prevention of lipid peroxidation (as indicated by levels of malondialdehyde in skin lipids after exposure to ultraviolet light) than either topical lutein or placebo.11 Diverse Cinical Benefits* Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.12 Suggested Adult Use: One softgel daily with food, or as directed by a health care professional. Does Not Contain: milk, egg, wheat, sugar, sweeteners, starch, salt, or preservatives. Scientific References 1. Berendschot TT, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Opthalmol Vis Sci. 2000 Oct; 41(11): 3322-6. 2. Berendschot TT, et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Opthalmol. 2002 Dec; 120(12): 1732-7. 3. Age-Related Eye Disease Study Research Group. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol. 2007 Sep; 125(9): 1225-32. 4. Seddon JM, et al. Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration. JAMA. 1994 Nov; 272(18):1413-1420. 5. www.nei.nih.gov/neitrials/viewStudyWeb.aspx?id=120. Clinical Studies Database. Age-Related Eye Disease Study 2 (AREDS2). Last Updated 2/28/2008. Viewed 5/15/2008. 6. Richer S, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr; 75(4): 216-230. 7. Stringham JM and Hammond BR. Macular pigment and visual performance under glare conditions. Optom Vis Sci. 2008 Feb; 85(2):82-8. 8. “Lutein and Zeaxanthin”. PDR Health. www.gettingwell.com/drug_info/nmdrugprofiles/nutsupdrugs/lut_0164.shtml 9. Chitchumroonchokchai C, et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr. 2004 Dec; 134(12): 3225-32. 10. Krinsky NI. Possible biologic mechanisms for a protective role of xanthophylls. J Nutr. 2002; 132: 540S-542S. 11. Palombo P, et al. Beneficial Long-Term Effects of Combined Oral/Topical Antioxidant Treatment with the Carotenoids Lutein and Zeaxanthin on Human Skin: A Double-Blind, Placebo-Controlled Study. Skin Pharmacol Physiol. 2007; 20: 199-210. 12. Mares-Perlman JA, et al. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002; 132: 518S-524S.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1901) Flax Seed Oil
Date:
August 07, 2008 01:53 PM
Flax seed naturally contains a variety of different categories of essential fatty acids, which includes alpha linoleic acid, linoleic acid, and omega-9 oleic acid. A lot of flax seed’s benefits are a function of its content of alpha linoleic acid, which is converted in the body to a longer chain of omega-3 EPA. Research has proven that supplementation with flax seed oil can help to increase the EPA concentrations in many tissues of the body. One of the main areas of research has been inflammation. Many factors contribute to inflammatory reactions, including omega-6 linoleic acid, which can be converted into pro-inflammatory substances. Flax alpha linoleic acid can convert into EPA, which has the ability to convert into a prostaglandin that has anti-inflammatory properties. In inflammatory states, alpha linoleic acid and EPA compete with linoleic acid for enzymatic metabolism, resulting in a decreased production of pro-inflammatory substances. Many studies have found that the use of flax seed oil in domestic food preparation can reduce the production of inflammatory cytokines. These studies have also shown the ability of omega-3 rich fish oils to inhibit inflammatory mechanisms in the autoimmune disease lupus nephritis, which lead to the investigation into flax having any abilities in this area. One trial found that 30g/d of flax seed was optimal for improving kidney function, decreasing inflammation, and reducing atherosclerotic development. Flax also contains antioxidants, which may be helpful to those who have SLE. Research has also been conducted to investigate the hormonal modulating effects of ingesting lignans, which are antioxidant and phyto-estrogenic compounds that are found in flax seed. Clinical evidence indicates that phytoestrogens have an anti-cancer effect on the breast. Experimental studies in animals and humans have also demonstrated flax’s anti-cancer effects, with a 1998 review indicating that the consumption of flax may be used as a secondary prevention method against breast cancer. Flax seed has also been shown to promote prostate health, as it plays a key role in the treatment of an enlarged prostate. The cardiovascular system is also another area of research focus for flax seed. One study showed that three months of flax seed supplementation resulted in LDL cholesterol levels dropping significantly, while HDL cholesterol did not change. Other research has shown serum lipid level reduction, but a large amount of flax seed was required to be consumed to get the same lipid-lowering effects as fish oils. Flax lignans also possess anti-platelet activating factor activity and antioxidant activity. Animal research has shown that flax seed reduced the development of aortic atherosclerosis’ by 46 percent and suppressed oxygen-free radicals. The research concluded that dietary flax seed supplementation could prevent hypercholesterolemia-related heart attack and strokes. Lastly, the elasticity of arteries is an important factor of circulatory function, which decreases as the cardiovascular risk increases. Research has proven that obese people consuming a diet high in ALA from flax seed oil experience a marked rise in arterial elasticity, which reflects a rapid improvement in the arterial circulation. Although flax seed offers many potential benefits, ingesting the right form of supplemental flax is crucial to gaining these benefits. Flax oil supplements are a good source of EFAs, but they do not provide great amounts of lignans. On the other hand, whole or ground flax seed is effective, but is not especially palatable. The best option of flax seed is the liquid in capsule form, as it delivers both EFAs and lignans. The nutritional value and certain beneficial results can be gained by consuming about 3,000 mg daily.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1857) Vitamin D Supplements
Date:
July 29, 2008 02:55 PM
Scientists at the Children’s Hospital and Research Center in Oakland, California have recently begun studying whether there is substantial convincing biological or behavioral evidence that links vitamin D deficiency to brain dysfunction. The study found that there is biological evidence which proves that there is an important role for vitamin D in the development of the brain and its function. Supplementation for groups that are chronically low in vitamin D has been found to be extremely beneficial. Vitamin D is involved in brain function through its wide distribution of vitamin D receptors throughout the brain. Vitamin D affects the proteins in the brain that are known to be involved directly with learning, memory, motor control, and possibly even maternal and social behavior. Research has shown that supplementation is beneficial to those groups whose vitamin D status is extremely low, especially nursing infants, the elderly, and African Americans, but the need for further study has been established. The authors of the study argue that vitamin D supplementation is necessary for those groups that are at risk. Increased vitamin D levels protect the body against osteoporosis, cancer, and multiple sclerosis. There is now evidence that suggests that vitamin D may help protect against a potentially dangerous rise in blood pressure which occurs in some people as they get older. A study that was published in the American Journal of Clinical Nutrition had researchers finding that as many as 60 percent of whites and more than 90 percent of blacks who participated in the third National Health and Nutrition Examination Survey had insufficient blood levels of vitamin D. Researchers also investigated the association between vitamin D, blood pressure, and age. This investigation found that people with lower blood levels of vitamin D had significantly higher increases in systolic blood pressure as they aged than did those people who had healthy levels. Actually, the age-related rise in blood pressure turned out to be 20 percent lower in those people who had healthy vitamin D levels, as oppose to those people who did not. This suggests that vitamin D deficiency may play a critical role in high blood pressure development. Many other studies have suggested that there is a role for vitamin D in reducing blood pressure. According to Vin Tangpricha MD, PhD., an assistant professor of Medicine in the Division of Endocrinology, Diabetes, and Lipids at Emory University School of Medicine, there is not enough evidence that vitamin D prevents hypertension available, however, because vitamin D insufficiency is highly prevalent throughout the United States, it may be a good idea to take a vitamin D supplement solely because of the strong evidence on vitamin D’s ability to prevent osteoporotic fractures. It has been noted that further studies are needed in order to determine vitamin D’s effect on blood pressure.
Additionally, it needs to be determined if giving all patients vitamin D will help lower blood pressure. Those people who have a family history of other risk factors that are associated with high blood pressure, such as being older than sixty-five, should have their blood pressure checked regularly. Be sure to look for more studies and information on the effects of supplemental vitamin D on both white and black habitants of the United States to help battle vitamin D deficiency. To learn more about supplemental vitamin D, contact your local health food provider.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1846) Magnesium Can Reduce Stress
Date:
April 25, 2008 01:36 PM
We here a lot about the need to take supplemental calcium, but what we don’t hear is that adequate levels of magnesium are essential in order to absorb and metabolize calcium. Today we have diets dangerously low in magnesium and many of us are not getting recommended amounts of this mineral. This is especially important when taking supplemental calcium both to maintain calcium-magnesium balance and to prevent buildup of excess calcium in the body. To ward off the negative effects of a prolonged period of stress or an overreaction to stress, calcium needs to be balanced with adequate amounts of magnesium. Going through a stressful period without sufficient magnesium can set up a deficit which, if not corrected, can linger, causing more stress and further health problems. Natural stress relief comes from magnesium. The solution to restoring healthy magnesium levels and balancing calcium intake is either done by change ones diet or adding magnesium supplement to their diet. By adding magnesium to ones diet one experiences natural stress relief. There is a product on the market called natural calm; it has been the best selling magnesium supplement for the past two years straight. This supplement mixes into water or juice where it can easily be drank and absorbed into the system. Just one serving can help one feel relieve from excess stress.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1771) The Prevention and Treatment or Prostate Cancer
Date:
April 10, 2008 01:36 PM
Last week I shared with you the controversy surrounding the use of PSA screening to determine the status of the prostate. There are many doctors who do not believe that using PSA is accurate enough to rely on for determining whether or not a high PSA indicates prostate cancer. Many men, who have a high PSA, after more detailed examination, did not have cancer and men with a low PSA did have cancer. Some physicians do not believe that the current methods of diagnosing prostate disorders are saving lives. Also, there is a group of physicians nationwide that strongly believe the best treatment is no treatment but rather a “watch and wait” approach. Prostate cancer usually is slow growing and more than 70% of men who develop it are over 65. The older a man is, the more likely he is to die of some other condition before his prostate cancer becomes a real threat. To reiterate, the American Cancer Society states, “at this time watchful waiting is a reasonable option for some men with slow growing cancers because it is not known whether active treatment such as surgery, radiation therapy or hormone therapy prolongs survival”. So what action can be taken? While prostate enlargement (BPH) is not related to prostate cancer, it can elevate PSA scores and can cause symptoms in 50% of men by age 80 and nearly all will show signs of BPH by age 85. If you have early symptoms of BPH such as frequency of urination, a burning feeling after urination and the caliber of stream that isn’t what it used to be, getting up several times through the night and low back pain, taking a good prostate support formula will be your best treatment and prevention. Most men will notice a remarkable improvement within a few weeks. A good prostate support formula will provide relief for 80-90% of all men from these annoying symptoms. But what about prostate cancer? The best cure for prostate cancer is prevention. I’ll give you a complete supplement program for prevention but first what about PSA testing? “I don’t believe in screening for something when it’s too late. By the time cancer develops a positive mammography or a true high PSA are likely too late, or if fortunate, that particular cancer will not be a problem. It makes far more sense to prevent the problem in the first place. And there is clear data, prevention is possible”. Dr. Robert J. Rowen, MD, Second Opinion, Soundview Communications. My recommendation, based on research of several scientific studies, includes various nutritional supplements and herbal extracts. Following are several very important studies that all men should be aware of. In 1966 Dr. Larry Clark of the University of Arizona published startling data suggesting that prostate cancer could be reduced by as much as an amazing 60% by supplemental yeast derived selenium, 200 mcg per day. Selenium is a powerful antioxidant and participates in key and crucial detoxification and free radical scavenging enzymes (80-90% of all disease is caused by free radical damage and inflammation). Selenium is one of a number of antioxidants to prevent this free radical damage; In 1999 a New Zealand study published in the British Journal of Cancer documented a 40% lower incident of prostate cancer in men with the highest levels of omega-3 fatty acids EPA and DHA in their blood. These findings have been confirmed in other omega-3 fatty acid studies. Conversely, another published report documents a high level of omega-6 to omega-3 fatty acids in invasive prostate tissue samples. Taken together with recent reports on high levels of omega-6 fatty acids (soy, sunflower, safflower, peanut, corn and most vegetable oils) linked to breast cancer, a common thread emerges. The American diet is overwhelmed with omega-6 oils. Excessive use of omega-6 fatty acids are cancer causing and also cause inflammation. Trans fatty acids from hydrogenated oils seriously add to the problem. There are other nutrients that have shown to reduce prostate-cancer risk. Vitamin E and lycopene have also shown to prevent prostate cancer. Lycopene is commonly found in tomatoes, especially cooked tomatoes. If you like spaghetti sauce or salsa, this is a great way to fight prostate cancer. While vitamin E, selenium, lycopene and omega-3 fatty acids are all great prostate supporting nutrients, through research I found a much more powerful combination of food grade molecules that can prevent and treat cancer. Extensive research in the last few years has revealed that regular consumption of certain fruits and vegetables can reduce the risk of prostate cancer. Fruits and vegetables having the highest degree of prostate cancer protection are the following: grapes (resveratrol), garlic, tomatoes, hot peppers, turmeric (curcumin), ginger, berries, milk thistle, cloves and fennel. These foods are protective because they are extremely active and excellent antioxidants. My favorite is turmeric (curcumin) because not only is it an antioxidant, it is also an anti-inflammatory agent. When it has this dual effect it is many times more potent than other types of food. In the United States there is 30 times more prostate cancers diagnosed than there are in India where turmeric is consumed liberally in most of the Indian dishes. Cancer does not begin shortly before it’s diagnosed. The origin of cancer may be years or decades in the process before it is even diagnosed as such. It is a multi-step process that goes through various phases such as cellular damage and transformation and culminates in the acquisition of invasive potential angiogenic properties and establishment of metastatic lesions. This process, and probably rightly so for all cancers, can be activated by any one of the various environmental carcinogens (cancer causing); all forms of tobacco products, industrial emissions, gasoline vapors, inflammatory agents, food coloring and preservatives, excessive UV rays, alcohol, hair dyes, cleaning products and drugs. The multi-step process of these cancer causing compounds progress in three stages; tumor initiation, promotion and progression phases. A powerful antioxidant/anti-inflammatory can prevent most if not all of the damaging effects when taken on a daily basis. Several population based studies indicate that people in Southeast Asian countries have a much lower risk of acquiring colon, gastrointestinal, prostate, breast and other cancers when compared to their western counterparts. It is very likely that constituents of their diet such as garlic, ginger, turmeric, onion, tomatoes, cruciferous vegetables, chili’s and green tea play an important role in their ability to avoid these cancers. These foods, or key active extracts from these foods, are known to block the NF-kB activation process. Also, several phytochemicals such as curcumin, resveratrol and green tea catechins have been shown to suppress AP-1. Several chemopreventative phytochemicals including curcumin, resveratrol and green tea have been recently shown to be powerful inhibitors of several growth factor receptors including EGFR. Curcumin also possesses the capacity to inhibit the activation of the EGF-Receptor indicating that it has the potential to break the autocrine loops that are established in several advanced cancers. Studies also suggest that curcumin, resveratrol and green tea can actually be used as safe, non-toxic treatments in drug resistant cancers. These natural phytochemicals (food grade) can help fight certain cancers thereby requiring a smaller dose of drug chemotherapy. They also can protect the body from the damages of drug chemotherapy and radiation. “This mini review presents evidence that chemopreventative agents, curcumin, green tea and resveratrol, can be used not just to prevent cancer but also to treat cancer. Because of their pharmacological safety, most chemopreventative agents can be used in combination with drug chemotherapeutic agents to enhance the affect at lower doses and thus minimize chemotherapy- induced toxicity. Because cancer is primarily a disease of old age, less toxic therapy is a major priority. This review reveals that molecular targets of chemopreventative agents are similar to those currently being used for the treatment of cancer. Tumor cells use multiple cell survival pathways to prevail and thus agents that can suppress multiple pathways have great potential for the treatment of cancer”1,2. Curcumin, resveratrol and green tea were as effective in preventing and treating certain cancers based on lab and animal studies. There have been approximately 20 human positive studies but much more needs to be done. From the research that I have done, I am convinced sufficiently enough to take many of these compounds as a preventative of cancer. These compounds are completely safe and non-toxic even in high doses. What does one have to lose? Why not take the positive preventative measure? –Compliments of Terry Naturally Ref: 1. Role of chemopreventaive agents in cancer therapy. Comprehensive Cancer Center Our Lady of Mercy Medical Center, New York Medical College, Bronx New York 2. Cytokine Research Section, Department of Bioimmuno Therapy, University of Texas, M.D Anderson Cancer Center, Houston Texas
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1748) Ubiquinol Reduced CoQ10
Date:
April 07, 2008 01:05 PM
Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol. Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements. In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur. CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations. While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy. In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation. A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer. As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed. The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation. Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1743) Passing on the Peptides: The Rise of Gluten-Free Diet And Fiber
Date:
January 02, 2008 03:22 PM
When going down the isles of any health food store, you'll find more and more cereals, breads, crackers, desserts, and supplements that claim to be gluten-free. Gluten refers to the peptides in wheat, rye, and barley that are problematic for gluten-sensitive individuals and cause great amounts of damage to the small intestine of those with celiac disease. About two million people in the US have celiac disease, and possibly more that have yet to be diagnosed. Gluten-free foods can help people with celiac disease, as well as many other conditions, feel better. There is currently no FDA regulation that defines the term "gluten-free" in labeling of foods, as long as the claim is not misleading. Many companies currently provide an extensive selection of gluten-free supplements so that they can meet the needs of gluten-free living. For those consumers desiring a daily multivitamin/mineral supplement, there are large varieties available from many different manufacturers. Many manufacturers are trying to create a product that is able to support the digestion of gluten. They want the peptide to be broken down so that its individual amino acid will no longer damage the gut or create food sensitivities. Supplemental digestive enzymes have been shown to give an increased advantaged to those who use a gluten-free diet along with enzymes. The Salba seed was recently introduced to those suffering from any level of gluten intolerance as a good source of fiber. It is the perfect solution because it is extremely high in fiber content for every serving and is a whole food source of fiber, which makes it better for you than a supplement that is manufactured solely to deliver fiber. Salba can be purchased as a seed and ground and pure cold-pressed oil. Because the vast majority of gluten-free foods that are available today are manufactured for great taste instead of nutrition, Salba is a great solution because it can be incorporated into gluten-free foods. Therefore, adding all the nutrition that is lacking in the products themselves, without adding any taste. Salba is also assimilated into the body easily because it is a whole food. By not labeling the absence or presence of gluten on products, retailers and consumers are greatly challenged. Although wheat is one of the major gluten-containing grains, it’s important to remember that rye, barley, and other grains are also a source of gluten. Retailers are able to help consumers determine which supplements are gluten-free by being more knowledgeable about ingredients containing gluten that are included in dietary supplements. For example, grains are used in the processing of many ingredients, so it is often necessary to seek out the hidden gluten. Among those ingredients that should be avoided by consumers seeking gluten-free products are modified starch, vegetable gum, and caramel. Gluten-intolerant consumers often deal with the issue of managing their own health while being around those who do not have to handle gluten-intolerant issues. Due to Salba’s neutral taste and ease of use, it is the perfect solution of gluten-free and non gluten-free members who are found in the same household and eating the same foods. Salba can help the whole family to improve their health dramatically.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1685) Set Your Snooze Control With Herbal Supplements
Date:
December 27, 2007 02:03 PM
Over one-third of adults say that they have symptoms of insomnia over the course of any one year. Unfortunately, about 10-15 percent of adults struggle with chronic insomnia. Lack of sleep can be traced back to too much stress, anxiety, caffeine, and discomfort from a medical problem, depression, work shift issues, or travel. For some people, insomnia presents itself as trouble falling asleep, while others have trouble staying asleep, and still others wake up too early. It all comes down to the same thing, people aren't getting enough restorative sleep, which leaves insomniacs feeling tired, irritable, and unfocused all day. Before pharmaceutical sleeping pills were on the market, herbs were the treatment of choice to cure a restless night. As the list of adverse effects to sleeping pills grows longer and longer, herbal sleep aids are again becoming the option of choice. Valerian has been known to give insomniacs better sleep for more than 1,000 years as it eases stress and has been scientifically documented for its sedative effect. Even better, valerian is non-addictive and includes no morning hangover from using it. A study on valerian extract found that the time to fall asleep can be reduced to that of what prescription sedatives promise. Earlier in the year, a similar study found that the combination of valerian and hops shortened the time it takes to fall asleep in a group of twenty-seven insomniacs from what was almost an hour to just about twelve minutes. Chamomile tea has a soothing, sedative effect and is still a pleasant drink. Additionally, chamomile can be used for anxiety and to soothe intestinal upset such as indigestion and heartburn. Other mildly sedating herbs include lemon balm, catnip, passion flower, and skullcap. Still other herbs to consider include corydalis, which encourages feelings of relaxation, in turn helping people to fall asleep, and lavender oil, which acts as a great calming agent. Green tea, which contains L-theanine, has a calming effect in the body and also strengthens immunity. When feelings of anxiety interfere with sleep, help can be found by taking L-theanine about an hour before one’s desired bedtime, as L-theanine interacts with the brain receptors that are associated with relaxation, therefore inducing a relaxed state of mind. Serotonin also plays a huge role in sleep, while 5-HTP helps to make this chemical. Studies have proven that by taking 5-HTP, insomnia can be helped a great deal in terms of sleep quality and longer REM sleep periods. About 100-300 mg of 5-HTP should be taken before bedtime for most people. Since some people can feel a little nauseous when first taking 5-HTP, starting with 50 mg for the first few nights and building up to higher doses is advised. Some reports of vivid dreams and even nightmares have been reported fro taking large amounts of 5-HTP and those people who are taking anti-depressants should not take 5-HTP. L-Tryptophan is an amino acid that is converted into serotonin and has been proven to be a successful remedy for insomnia. Although this supplement was unavailable for several years, it is now back on the market. Melatonin also plays an important role in regulating the body's clock as it is secreted for several hours each night. People with insomnia tend to have lower levels. Therefore, taking supplemental melatonin, especially in a time-release form, an hour or so before one’s desired bedtime can help to get back into a better sleep schedule. Lastly, magnesium can help resolve sleep issues, especially in those people who have sleep problems because of restless leg syndrome (RLS). No matter what herbal supplement or mineral you decide to use, always consult your health care practitioner before adding vitamin supplements and herbs to ones diet while taking prescription medication. The above mentioned herbal supplements can be found at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1683) Natural Hormone Balance for Women
Date:
December 25, 2007 11:18 AM
The majority of women are affected by moderate-to-severe menopausal symptoms and premenstrual syndrome (PMS) at some point in their life. PMS that is clinically diagnosed consists of symptoms that are so severe and pervasive that careers, social interactions, and family lives are negatively affected. This occurs in eight to twenty percent of women in the Western world. Menopause and PMS are both characterized by a severe fluctuation or major falling of the female hormones estrogen, progesterone, and prolactin. Since many examples of women who are barely affected by natural changes exist, it can be logically inferred that female hormones are capable of remaining close to balanced, while others experience hormones that swing abruptly from one extreme to the next, causing severe mood swings. Although changes in hormone levels are the reason menopause and PMS occur, women do have some control over the severity of their symptoms. There are many natural approaches to hormone balance along with other medical interventions that can be used either separate or together. However, one must remember that women are biologically programmed to have multiple children, which therefore, would limit the number of menstrual cycles in a lifetime. Additionally, women are now living thirty years past menopause, an experience that is relatively new. Also, a lot of the pain and anguish that is associated with menopause and PMS is actually related to obesity, high-calorie eating habits, and inactivity. Normal body weight and regular exercise often leads to mild or inconsequential PMS. In 2002, estrogen and progesterone hormone replacement therapy, which is the standard treatment for menopausal symptoms, came under scrutiny after the publication of research that found that supplementation of estrogen significantly increases the risk for breast and ovarian cancer. Supplementing estrogen also does not protect against cardiovascular disease. As a result, US-dispensed prescriptions for estrogen declined from ninety-one million in 2001 to fifty-seven million in 2003. It has been found that a lot of the excess risk for breast and ovarian cancer was due to prescriptions being refilled indefinitely instead of hormone replacement therapy only being used at the onset of menopause. Additionally, supplemental estrogen was not paired and balanced with progesterone, causing a greater risk. Either way, the door to natural alternatives was opened wide, especially for those patients who have a family history of reproductive cancer. Natural therapy for menopause and PMS is based upon phytoestrogens.
Phytoestrogens are plant compounds that contain chemical structures which resemble estrogen. These plant compounds can exert weak estrogenic or antiestrogenic effects. Isoflavones from legumes such as soybean, red clover, licorice, as well as lignans like flaxseed and milk thistle are the most common and familiar phytoestrogens. Black cohosh has been shown to have antiestrogenic effects only. Phytoestrogens have been proven to reduce the risk for estrogen-dependent breast, uterine, and ovarian cancers as well as hot flashes, night sweats, and sleep disturbances. Although phytoestrogens do a good job at protecting women from symptoms of excess estrogen, phytoestrogens cannot replace estrogen when there isn’t enough. They don’t help with vaginal wall atrophy and dryness, thinning hair, lack of sexual desire, menopause-related urogenital itching, or infertility. For the best results, supplements of soy and red clover isoflavone should be taken 2-3 times daily. Although there are no herbal alternatives that actually raise levels of estrogen, natural medicine such as dong quai, licorice, milk thistle, ginseng, pycnogenol, and pollen for menopause and calcium, magnesium, B6, chastre tree, dong quai, and ginseng for PMS can balance existing female hormones and provide relief from symptoms.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1682) Support Healthy Joint Function With Discount Vitamins
Date:
November 22, 2007 11:05 AM
The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime. Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones. Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain. Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue. A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders. A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints. The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover. Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids. Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks. Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage. Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement. It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that. That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results. Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density. There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium. You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1638) The Healing Power Of Borage Oil’s GLA
Date:
November 13, 2007 10:22 AM
Borage is otherwise called the starflower, and the borage oil extracted from its seeds is very rich in GLA, gamma linolenic acid, a polyunsaturated fatty acid also obtainable from evening primrose oil. Borage, however, is richer in GLA, and is therefore a more economical source that the evening primrose. A shrub, frequently seen in gardens, borage has historically been used as a salad food, and also in soups, and borage honey is prized in many quarters. Now, however, its main use is for the GLA extracted from the seed, which provides a higher yield of GLA than any other source. Borage seed oil contains up to 25% GLA, compared to the 17% from blackcurrant oil and 9% from evening primrose oil. The importance of GLA to the body’s biochemistry is inestimable, and cannot be overstated. It is not so much the GLA that is so important, but the prostaglandin to which it is converted in the body. Prostaglandin E1 is a hormone-like substance that plays a part in many of the biochemical and metabolic processes of the body. Examples include the control of the immune system and inflammatory response, some kidney functions, and the tone of the arterial muscles, so important in the health of the cardiovascular system. A good fatty acid metabolism benefits some very important aspects of our health such as maintaining a good blood pressure, low cholesterol levels, preventing inflammatory and immune system conditions such as arthritis, allergies and some skin diseases such as eczema and psoriasis, and also improving the strength of the keratin-dependent tissues such as our nails and hair. A deficiency in essential fatty acids also seems to stimulate the overproduction of a hormone in women called prolactin that can lead to the severe mood changes commonly referred to as pre-menstrual syndrome, or PMS. GLA appears to have a beneficial effect in the treatment of PMS, and some other conditions such as breast discomfort. Gamma linolenic acid is created in the body from linoleic acid, of which there is a plentiful supply in margarine, vegetable oils and many processed foods, but there is a problem. Fatty acid molecules come in different isomeric forms, in which although the chemical is the same, the geometry or ‘stereochemistry’ is different. The healthy form is the ‘cis’ formation, and the other is the ‘trans’ stereoisomer. The trans fatty acids are formed by hydrogenation of oils to make them semi-solid, and more suitable for spreading. This hydrogenation process causes an irreversible change in the geometry of the fatty acid that can block the conversion of linoleic acid to GLA in the body. Hence, although most of the western population has more than sufficient linoleic acid in their diets, many who eat an excess of trans fats have a deficiency of GLA. Some B vitamin deficiencies and a deficiency in certain minerals exacerbate this situation, and a gamma linolenic acid supplement is needed. Additional to this, the enzyme responsible for the conversion, delta-6-desaturase (D6D) can be affected by many modern environmental factors such as smoking, stress, alcohol, excessive animal fat consumption and even excessive linoleic acid consumption. The solution to all of this is GLA which does not require any enzymes for its creation, and supplemental GLA from any source can immediately take part in the biochemical pathway to the creation of the prostaglandin eicosanoids. GLA provides the means and the resultant prostaglandins carry out the job of regulating the hormonal activity within human biochemistry. Prostaglandins help to regulate the function of many of the cells in the body, such as the smooth muscle cells of the arteries and veins that cause constriction or dilation, and on the stickiness of blood platelets causing their aggregation. They are important in the regulation of such functions as blood clotting, fluid balance and the production and balance of hormones. The anti-inflammatory properties of prostaglandin E1 are very important to the way that the body reacts to breaches by foreign invaders, and it is also thought to act to thin the blood and cause dilation of blood vessels, hence its effect in lowering the blood pressure. So what does this mean to you, apart from the effects of the fatty acid on PMS? Borage oil can be used to treat a large number of different symptoms associated with a shortage of GLA and prostaglandin E1, and here are a few of the conditions for which a GLA supplement has been found beneficial. A deficiency in GLA and other essential fatty acids can lead to loss of bone mass and subsequent osteoporosis and it is thought that fatty acids help the absorption of calcium by the digestive system, and to increase its deposit in bones. It can be used to increase bone mass and density and therefore strengthen the bones of those affected by osteoporosis. This is partially due to the hormone regulatory effect GLA has on the body. Allergies appear to be very personal responses by the immune system to specific substances, and while borage oil has proved beneficial in a few allergies, and prostaglandins are known to regulate the activity of the immune response, the effectiveness of GLA treatment for allergies has been mixed. There is evidence that it can affect some cases, but not most. GLA from borage oil can reduce the swelling and pain of rheumatoid arthritis, and helps to ease morning stiffness. Its effectiveness seems mixed, and you should try it for two or three months to determine if it helps you personally. Be careful, however, since some believe that it might react with some of the non-steroidal anti-inflammatory drugs (NSAID) used to treat this condition. Ibuprofen is one, so check with your physician before trying it. If you suffer from high blood pressure, borage oil used in conjunction with Omega-3 fish oils might lower it, though more research is needed. There is a belief that the GLA is not the active agent here since Omega-3 oils are known to help to reduce hypertension, though the effect of prostaglandins on the factors that can reduce blood pressure is inarguable. The healing power of borage oil should not be underestimated, and it has been used for centuries in folk medicine to treat many conditions, especially those that science has found to be caused by the immune system and the inflammatory response. Borage oil can be found at any Health Food Store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1629) Lutein - A plant pigment provides sun protection from the inside out.
Date:
July 09, 2007 01:21 PM
A plant pigment provides sun protection from the inside out. Energy on earth begins with the sun’s rays, which spark the photosynthesis in plants that ultimately powers all life. (Petroleum is the residue of prehistoric plants crushed over eons into liquid form.) But the sun’s energy is not totally benign for us humans; excess exposure can cause skin to wrinkle and eyesight to dim. Enter lutein. This plant chemical, reddish-orange like the setting sun, has become a hot commodity over the past several years because of its ability to protect both eyes and skin against sun damage. A member of the carotenoid family of nutrients, lutein is generally paired with its partner, Zeaxanthin, in a wide variety of foods, including egg yolks, fruits, corn and leafy greens such as spinach (where its bright color is masked by the green of chlorophyll). That’s a good thing, since your body can’t make lutein and so needs to obtain it from your diet. Skin Shield The sun produces a whole spectrum of light rays, from the visible (red through violet) to the invisible or ultraviolet (UV). UV rays—both ultraviolet-A (UVA) and ultraviolet-B (UVB)—are troublemakers. They attack collagen, the protein that gives skin its shape, which leads to wrinkles and other signs of aging. What’s worse, UV is also capable of damaging skin cell DNA, a process that can promote cancer development. And UV isn’t the only culprit: The sun’s visible blue rays are believed to help create harmful molecules called free radicals within the skin. The clue to lutein’s importance in fending off skin damage lies in the fact that it is found throughout both the outer (epidermis) and inner (dermis) skin layers, where as an antioxidant it fights free radicals and as an orange pigment it soaks up blue light. In one study, using lutein both orally and topically produced improvements in skin hydration and suppleness (Skin Pharmacology and Physiology 4/19/07). Lutein has also shown an ability to counter the inflammation and immune system suppression associated with excess UV exposure (Journal of Investigative Dermatology 2/04). Lutein Gleanings What is it? A red orange carotenoid found in a number of fruits and vegetables, generally with a similar compound called Zeaxanthin. What does it do? This powerful antioxidant helps protect the eyes against both cataracts and age-related macular degeneration (AMD); it also appears to defend the skin against sun damage and has been associated with reduced arterial wall thickness, a measure of cardiovascular health. The Eyes Have It Your eyes, like your skin, are directly exposed to the sun’s UV rays. Such exposure can cloud the eye’s lens to create cataracts. It can also disrupt the retina at the back of the eye particularly the macula, the part of the retina responsible for clear central vision—which can result in age-related macular degeneration. Not surprisingly, the eye is yet another one of the body’s lutein hot spots. This pigment is especially concentrated in the macula; in fact, of the 600 or so carotenoids that exist in nature, only lutein and Zeaxanthin are found within this all important structure. So it also isn’t surprising to learn that they Eye Disease Case Control Study, one of the first large-scale investigations into carotenoids and eye health, found a link between reduced AMD risk and high levels of lutein and Zeaxanthin. Current research has focused on the use of supplemental lutein in AMD patients, with promising results. It isn’t only the outside of your body that may benefit from lutein. When oxidized by free radicals, LDL cholesterol settles into arterial walls. Lutein may help slow this process; in one study, people with the most lutein in their blood had 80% less vessel-wall thickening than those with the least (circulation 6/19/01). So enjoy some fun in the sun. But respect the power of those golden rays, and let lutein help make playtime a safe time. –Lisa James.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1584) Active Coenzyme Q10
Date:
July 07, 2007 01:30 PM
Active CoQ10
The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.
In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. What is ubiquinol? Is it the same or different from CoQ10?
A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.
Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?
A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.
So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.
Q. What are the health benefits of CoQ10 and Ubiquinol?
A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.
In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.
Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?
A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.
Q. How might ubiquinol be important for the heart?
A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.
The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.
Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.
The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.
Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.
Q. What have been the results of research studies with Ubiquinol?
A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.
Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Should I take CoQ10 or ubiquinol? How much should I take?
A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.
Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.
Conclusion
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1583) Supplements for Children
Date:
June 26, 2007 09:51 PM
Supplements for Children
While most parents try hard to make nutritious meals for their family, most children find the appeal of refined, fast, and junk food simply overwhelming. And, sadly, increasingly easy to buy and consume, as well. From kindergarten through 12th grade, in both grade schools and high schools, vending machines offer calorie laden candy bars, sugar-filled soft drinks, and snack foods loaded with fat and salt. Many school cafeterias actually sell fast-food to children for lunch every day. In fact, it seems almost everywhere children go and gather, visually enticing but nutritionally lacking snacks and soft drinks are sure to be available.
Determined to counteract this disturbing trend, parents everywhere are urgently seeking solutions to help their children get the nutrition they need. One answer is supplemental multivitamins. There are certainly plenty of multivitamins formulated for children currently on the market. However, these products vary considerably in quality and content. Some lack certain vital nutrients. Some taste terrible. Still others are loaded with sugar and artificial flavorings. The good news is that there are superior multivitamins and exceptional immune boosting products formulated specifically for children that actually taste great. In this issue of Ask the Doctor, we will discuss childhood nutrition and how to help ensure your children’s health with high quality, 100% natural flavored nutritional supplements.
Q. Do children really benefit from vitamin supplements? Can’t I make sure they get the vitamins and minerals they need from meals?
A. Even the most nutritionally vigilant parent cannot be 100% certain what nutrients are in the food they serve their children. That’s because there’s so much variability in the food we prepare. For instance, fat-soluble vitamins can withstand normal cooking, but vitamins A and E are gradually destroyed by exposure to air. Water-soluble vitamins such as B1, B6, folic acid, and pantothenic acid are destroyed by heat. Vitamin B2 is destroyed by light and heat, while light and air destroy vitamin C. Certain food preservatives and preparation methods also destroy the vitamins in food. To further complicate matters, some fruit and vegetables are grown and harvested in such a way that does not promote nutrient content – so even raw foods may be lacking.
Then there are those crazy food phases all children seemingly go through. While these phases are generally harmless in the long run, a recent alarming exception was in the news. A five-year old boy ate nothing but cheese pizza, Pop-tarts, biscuits, and water, refusing fruits, vegetables, juices and vitamins. He slowly developed limp, swollen gums, and small purple spots appeared on his skin. After five months of this extremely deficient diet, he was unable to walk or get out of bed because the pain was so severe. Doctors diagnosed the boy as having a severe vitamin C deficiency after ruling out other ailments such as leukemia. Within a week of getting vitamin C supplements, the boy’s pain and other symptoms were completely resolved. Obviously, this little boy’s story is unusual. However, even mild food phases (such as “If It’s Green It Must Be Yucky” or “The Only Good Crust Is A Cut-Off Crust”) can result in awfully lop-sided nutrition.
Q. Can multivitamins help my child’s performance in school?
A. Most teachers firmly believe that nutrition and learning go hand in hand. They are convinced that children who are well nourished possess the mental stamina that’s needed to learn and retain even difficult concepts. But can multivitamins help children become better students?
Two independent research teams recently conducted randomized trials to find the answer. The researchers followed 245 school-children aged 6 to 12 years for three months. They gave half of the children multivitamin tablets every day, and half of the children placebos. When the children were tested, the children in the multivitamins group showed an increase in their nonverbal intelligence scores. Nonverbal intelligence is closely associated with academic performance.
Q. I can’t get my children to take 100% natural flavored multivitamins because they don’t taste very appealing. Isn’t there some way to make a 100% natural multivitamin taste good enough for my children to willingly take?
A. Yes, there is! Because most children need chewable multivitamins, manufacturers need to contend with the truly terrible taste of certain minerals. Magnesium, iodine, copper, and iron are probably the worst tasting. Some solve this dilemma by skimping on the amounts of these minerals in their children’s formulas. Others cover up the bad taste with either massive amounts of sugar or artificial flavors, or both.
However, a select few multivitamin makers have discovered how to offer a natural flavored, great tasting children’s multivitamin that contains these vital minerals. The best children’s vitamins are prepared in a base of natural fruit that provides both antioxidants and other healthy phytonutrients. Children’s multivitamins made in such a fruit base have very low sugar content, as well, providing as little as four calories a day. Fructose – fruit sugar – is the preferred sweetening agent, in addition to the fruit content.
Q. What vitamins should be in a multivitamin for children?
A. There are several vitamins and minerals that children need to take each and every day. They include biotin, folate, niacin, pantothenic acid, vitamins B12, B1, A, B6, C, D, E, and K. Let’s review a few. We’ll start with folate, one of the B vitamins. This vital vitamin helps the body use protein, helps make DNA, helps cells grow and divide, and keeps the nervous system healthy. In fact, folate is so important to children that the Food and Drug Administration (FDA) mandated that folate must be added to many foods most children eat daily. Since 1998, cereal, enriched bread, flour corn meal, rice, and pasta have been folate-fortified with this B vitamin.
One of folate’s vital actions is the reduction of homocysteine levels in the blood. Homocysteine is an amino acid (the building block of protein) that is normally produced in the human body. Research has shown that high levels of homocysteine can irritate blood vessels, make blood clot more easily than it should, and cause blockages in arteries increasing the risk of heart attacks and strokes .
However, study after study has proven that taking folate reduces harmful homocysteine levels. While most of this research has been in adults, a recent study looked at children’s homocysteine levels. Researchers examined over 3500 children and discovered that high homocysteine levels increased the risk for heart disease in these children, especially as they grow. The researchers leading this study reinforced how critical folate is for all children.
Other critical vitamins for children are the vitamins C and E. The rates of childhood asthma have increased significantly here in the
Q. Which minerals do children need?
A. It is absolutely crucial that children get calcium, chromium, iron, magnesium, manganese, selenium, zinc, and phosphorus every day. Sadly, however, the majority of our children are not getting the recommended amounts of many of these vital minerals. Children in
According to statistics from the National Institutes of Health, only 13.5 percent of girls and 36.3 percent of boys age 12 to 19 in the
Lack of adequate calcium has immediate consequences for children, as well. The number of fractures among children and young adults has increased as a direct result of poor calcium intake. Pediatricians are also seeing children with rickets, a bone disease caused by low levels of vitamin D. Rickets became almost nonexistent after vitamin D was added to milk in the 1950s, but, due to lower milk consumption, is now appearing at greater rates around the country. And milk itself can be problematic for some children. Aside from alarming reports of hormones and herbicides in commercial dairy factory milk, even organic milk is not tolerated by all because of lactose intolerance and allergies.
Zinc is another mineral that’s vital for children. Because zinc is critical for normal growth and development, children need to take it every day. A study published in the Journal of the American Dietetic Association, however, found more than half of US children ages two to 10 years fail to get the recommended daily allowance (RDA) for zinc. What’s even more troubling is that zinc is vitally connected to children’s ability to process information, pay attention, as well as remember and retain new information
Zinc does a lot to keep children healthy. More than 200 enzymes in our bodies rely on zinc. However, it’s zinc’s ability to connect with our immune systems to help fight infections that is crucial for children. While researchers are not certain how zinc precisely boosts a child’s immunity, they think that zinc might fight pneumonia and other infections by either enhancing the body’s immune status, preventing the infection from establishing itself, or improving the immune system’s ability to rid itself of the infecting organism. It’s possible that zinc does all three.
Q. No matter what I do, my children seem to come down with bad colds each year. Besides giving them a multivitamin, are there other nutritional supplements that can keep my children healthy?
A. Absolutely! In fact, there are 100% natural flavored children’s immune formula nutritional supplements that contain their good buddy zinc, vitamins B6, C, and A (as beta carotene), plus elderberry extract. Elderberry extract has been used as a traditional medicine for hundreds of years to treat colds and flu. And as it so often happens, scientific research has validated this use. In fact, scientists have discovered that elderberry keeps viruses from invading other cells and replicating. It also spurs important immune cells into action to fight invading germs.
While we previously discussed vitamin C’s ability to help children with asthma breathe easier, it also provides powerful immune protection. It speeds up the healing of wounds, such as those knee and elbow scrapes so common in childhood. However, vitamin C is a water-soluble vitamin and can’t be stored in the body. It must be replenished every day. When children are under increased stress (like when they get sick with a cold or flu), their vitamin C levels are more rapidly depleted.
Vitamin B6 is also water-soluble and can only work in children’s bodies for eight hours. Then more B6 must be obtained. Vitamin B6 strengthens the immune system by helping white blood cells make antibodies. Vitamin A helps make lysozymes, important anti-infectious agents found in tears, saliva, and sweat. It also stimulates the thymus gland, an important immune organ, especially in children, to work better.
Q. Should children take an immune formula every day or only when they are sick?
A. It can be taken several ways. Some parents may want to give the formula when school first starts or other times that their children are exposed to lots of germs. For a child who suffers from asthma or seasonal allergies or just seems to get sick frequently, parents could provide the immune formula every day, increasing the dose when needed. And still others might feel it’s best to give their children the immune formula only whey they do catch a cold or have the flu.
No matter how it is given, the 100% all natural flavored, immune boosting nutritional supplement can provide powerful protection against all those disease-causing germs your children are exposed to every day.
Conclusion
The nutritional choices we make for our children today will have a profound effect on their health tomorrow. Recent research has revealed that diabetes, heart disease, obesity, osteoporosis, and cancer in adults often result form nutritional deficiencies that occurred in childhood.
Thankfully, the reverse is just as true. This means that children who are well nourished with an optimal intake of minerals, vitamins, and helpful herbs can grow into healthy and happy adults. Providing high quality multivitamins and immune boosting nutritional supplements for our children can be an important part of that process.
-- Vitanet, LLC
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1578) Vitamin D Shows Promise For Cancer Prevention…
Date:
June 19, 2007 02:17 PM
Vitamin D Shows Promise For Cancer Prevention…Researchers from the Creighton University School of Medicine, Nebraska, studied 1,179 healthy, postmenopausal women over four years to determine the benefits of vitamin D3 for cancer prevention. The women, from rural Nebraska, supplemented their diet with randomly assigned daily dosages of 1,400 mg – 1,500 mg supplemental calcium; 1,400 – 1,500 milligrams supplement calcium plus 1,100 IU of vitamin D3, or placebo. The women were 55 years or older and free from known cancers for at least 10 years prior to entering the study. Over the four-year trial, women in the calcium with vitamin D3 group experienced a 60 percent decrease in cancer risk compared to the placebo group. Researchers also found a 77 percent cancer risk reduction with the calcium with vitamin D3 group in the last three years of the study. Further studies are needed to see if the results apply to other populations. (American Journal of Clinical Nutrition, June 8, 2007, volume 85, issue 6, pages 1586-1591)
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1566) The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
Date:
May 18, 2007 01:06 PM
The Awesome Foursome: Coenzyme Q10, L-Carnitine,
D-Ribose, Magnesium
The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.
Coenzyme Q10:
Energy Recycling through the Electron Transport Chain
Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.
Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.
In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.
What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.
Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.
L-Carnitine:
Transporting the Cellular Energy Fuel
Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.
D-Ribose:
Rebuilding the Cellular Energy Pool
As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.
When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.
Ribose is the only compound used by the body to refill this energy pool. Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency. Ribose is made naturally in the cells from glucose. In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis. So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.
Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy. Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days. But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose. Conditions like ischemic heart disease or congestive heart failure fall into this category. In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.
Magnesium:
Switching on the Energy Enzymes
Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism. Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work. Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.
Magnesium deficiency reduces the activity of important enzymes used in energy metabolism. Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function. Small changes in magnesium levels can have a substantial effect on heart and blood vessel function. While magnesium is found in most foods - particularly vegetables - deficiencies are increasing. Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.
Supporting the Links in The Energy Cycle Chain – the Synergy
Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.
The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.
The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.
Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.
These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.
The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.
L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1539) Do you experience muscle pain and inflammation?
Date:
April 25, 2007 03:30 PM
FlexAgility MAX Everyone experiences muscle pain and inflammation due to overuse and exertion. We’ve all had those softball games, weekend camping trips or chore-intensive days when our body lets us know we’ve overdone it. So, what can you do about it? Well, fortunately, there is a proprietary formula with clinically studied ingredients that provides a natural solution: FlexAgility MAX. FlexAgility MAX is designed to reduce pain and inflammation due to overuse. Its clinically studied ingredients have been shown to help balance the body’s own inflammatory response. Let’s take a look at FlexAgility MAX and answer a few questions you may have about it. Q. What is inflammation? Why does it happen? A. Inflammation is actually an essential part of your body’s natural healing process. When some form of physical stress affects the body, the immune system responds by supplying defensive compounds to the stressed site. This is what causes the fluid build-up, pain and redness we typically associate with inflammation. And until the situation is resolved those symptoms will stick around. So, why is that good? Because without these signals – pain and inflammation – we’d probably do even more damage. In a sense, pain and inflammation are very effective stop signs. The problem is, if our bodies are continuously bombarded by factors that trigger inflammation, these defenders (and their symptoms) are always around. This can mean unnecessary pain and inflammation following overuse and exertion. Q. What does FlexAgility MAX have to do with inflammation? A. FlexAgility MAX provides triple-action activity against occasional pain and inflammation, with powerful antioxidant free-radical scavengers, the enzyme bromelain, and a natural COX-2 inhibitor. Q. So what is COX-2 and why should I inhibit it? A. We’ve all been hearing a lot in the news about COX-2 inhibition and may have wondered about its connection to pain and inflammation. Let’s take a look: Cyclooxygenase is an enzyme that comes in two main types, abbreviated for convenience: COX-1 and COX-2. The COX enzymes regulate compounds involved with inflammation, including prostaglandins. COX-1 is found throughout the body, and maintains the integrity of the stomach lining, circulation and kidneys. COX-2 on the other hand, cruises along the central nervous system – it’s much more attuned to our brain’s sense of “what hurts.” Primarily activated by inflammatory stress, COX-2 generates prostaglandins – the hormone-like defensive compounds that cause the responses we associate with pain and inflammation due to overuse. You can understand why so much research has focused on COX-2 inhibition. Decreasing its activity means short-circuiting the “inflammation cascade” that follows occasional overuse. Because COX-1 is associated with a healthy stomach lining, it is not an enzyme you want to inhibit. Unfortunately, many products don’t know the difference between COX-1 and COX-2 – filing both with one blast. Fortunately, there are ingredients in FlexAgility MAX that can tell them apart. One of them is IsoOxygene. IsoOxygene is a patented hops extract shown in scientific studies to significantly inhibit COX-2, while leaving COX-1 alone. And, it is a 20 times more potent COX-2 inhibitor than other tested popular botanic products, including curcumin and grape seed. Q. How do antioxidants support the body during times of inflammation due to overuse? A. Overall, the body ahs a pretty darn good repair system. However, oxidative stress due to free radical damage can take its toll, especially during times of occasional physical stress. Free radicals and reactive oxygen species can damage cells, because they are hungry, unstable molecules in search of electrons. To find them, they attack other cells. These pillaged cells then become free radicals themselves, setting off a chain reaction of oxidative stress. Free radicals are formed during the body’s normal functions, and can have benefits, such as neutralizing viruses and bacteria. However, in doing do, they erode the body’s own antioxidant defenses, too. And, free radicals typically become very active during times of inflammation due to overuse or other stressors. The good news is that the herbal and antioxidant elements in FlexAgility MAX help support the body’s own natural anti-inflammatory defenses. Take vitamin C, for instance. This extremely well-known antioxidant has been scientifically studied for its beneficial effects on muscle, collagen and connective tissue health. Collagen and connective tissue is what helps hold us together – literally. And famous antioxidant, green tea, has been well-studied for the benefits of a polyphenol called epigallocatechin-3-gallate, or simply EGCG. In scientific and clinical studies, EGCG from green tea works as an overall antioxidant, scavenging free radicals, and supporting healthy collagen. In fact, one study showed that green tea polyphenols supported collagen health by 50% versus only 16% in controls. The green tea extract in FlexAgility MAX is especially focused on these beneficial polyphenols. It’s standardized to contain 70% polyphenols – half from EGCG. The green tea acts in concert with elderberry and ginger in the formula to help prevent oxidative stress to the body due to occasional overuse. Anthocyanins are natural antioxidants found in berries and vegetables. Black elderberry extract, one of the herbal ingredients in FlexAgility MAX, was shown in scientific studies to be more bioavailable – that is, more readily used by the body – than the natural bioflavonoids of other plants. Again, antioxidants help keep the body in optimum health- especially during times of physical stress. Ginger, used for centuries in Ayurvedic medicine, provides strong, natural antioxidant activity. In fact, a recent scientific study found more than 50 separate antioxidants in ginger root. Of course, there are many components of plants that show strong antioxidant properties. A scientific study comparing flavonoid antioxidant activity and inflammation have shown that rutin was the most effective in reducing the inflammation cascade. Boswellia serrata is a tree found growing in the dry, hilly regions of Another antioxidant ingredient in FlexAgility MAX, N-acetylcysteine (NAC), even helps the body produce more of its own antioxidants, cysteine and glutathione. In a double-blind, placebo-controlled clinical study, N-acetylcysteine inhibited occasional pain and inflammation due to overuse and attenuated fatigue by 26% compared to controls! N-acetylcysteine has also been shown in scientific tests to act as an antioxidant, supporting healthy collagen and synovial fluid. The last ingredient, bromelain, provides the enzymatic pathway used by FlexAgility MAX. Bromelain is a proteolytic enzyme derived from pineapple. Clinical and scientific studies showed benefits from bromelain in reducing pain and inflammation from occasional overuse. So, there you have it- the triple action of FlexAgility MAX: COX-2 inhibition (and COX-1 sparing), antioxidant benefits, and enzyme support. Q. Is there another product you’d recommend that I use with FlexAgility MAX? A. One other product I recommend without hesitation is GS-500, a glucosamine sulfate supplement that has been shown to help build and support cartilage. The body’s connective tissue and cartilage include a natural compound called glucosamine. Supplemental glucosamine sulfate is up to 98% absorbable, so more glucosamine reaches the target structures. It has been clinically studied on its effect in building cartilage. About Enzymatic Therapy: Like Chris, Enzymatic Therapy is a trailblazer. Since our founding in 1981, we’ve been leading the industry with innovative natural products. After all, in 1993, Enzymatic Therapy introduced glucosamine sulfate, shown to help build and support cartilage, to the In the intervening years, Enzymatic Therapy has been at the frontline of innovation and invention. Many revolutionary precuts, including Saventaro, Cell Forte, Heartburn Free, Petadolex Patented Brain Support, Whole Body Cleanse, Earth’s Promise, Hot Plants for Him and Hot Plants for Her have been introduced by Enzymatic Therapy. One of the newest products, (and the reason you’re reading this) is FlexAgility MAX. FlexAgility MAX works with the body’s own natural anti-inflammatory pathways to relieve pain and reduce inflammation due to occasional overuse. Our proprietary FlexBend of ingredients, combined with antioxidants and the proteolytic enzyme, bromelain, is unique among natural products.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1529) Learn about Bone Health!
Date:
April 20, 2007 12:43 PM
Bone Health Approximately 44 million American women and men aged 50 and older have osteoporosis (severe bone loss) or osteopenia (mild bone loss), with women being affected about twice as often as men. At least 1.5 million fractures of the hip, vertebra (back or neck), or wrist occur each year in the United States as a result of osteoporosis, and the annual cost of treating this disorder is nearly $14 billion and rising. Unfortunately, the toll in human suffering and loss of independence is even greater. In this issue of Ask the Doctor, we will discuss the risk factors for osteoporosis and some key nutrients you can add to your diet that can minimize bone loss and reduce your chances of developing this disease. Q. What are the risk factors for osteoporosis? A. Small body frame, underweight, Caucasian or Asian race, a sedentary lifestyle, cigarette smoking, excessive alcohol or caffeine intake, high intake of carbonated beverages (especially colas), and having other family members with osteoporosis all increase personal risk of developing the disease. Certain medical conditions, including diabetes, celiac disease, hyperthyroidism, rheumatoid arthritis, chronic obstructive lung disease, hyperadrenalism, and hyperparathyroidism, are all associated with an increased risk of osteoporosis. Some medications increase the rate at which bone is lost; these include drugs prescribed for the treatment of seizures, drugs used for blood thinning, steroids such as prednisone, aluminum-containing antacids, and loop diuretics (furosemide {Lasix}). Q. Isn’t bone loss just a normal consequence of aging? A. Although bone mass normally declines after the age of 35, bone loss severe enough to cause fractures after just minor trauma (such as bump or fall) seems to be a relatively new phenomenon. Osteoporosis was rare in the late 19th century, and it was not until around 1920 that the condition began to attract attention among doctors. Since that time, the percentage of people who develop osteoporosis has continued to increase. For example, the age-adjusted prevalence of osteoporosis in Q. Can osteoporosis be prevented? A. Engaging in regular weight bearing exercise, avoiding excessive consumption of alcohol and caffeine, and quitting smoking will slow the rate of bone loss. Eating adequate, but not excessive, amounts of protein also enhances bone health. In addition, a growing body of research has shown that supplementing with various vitamins and minerals may not only help prevent, but in some cases actually reverse, bone loss. At least 15 different nutrients have been found to play a role in bone health. Q. What type of calcium is best? A. For most people, calcium salts are absorbed about the same, between 30% and 40% of the administered dose. People who low stomach acid (hypochlorhydria) should not use calcium carbonate, because that form of calcium is absorbed poorly in the absence of stomach acid. Calcium phosphate may be preferable for many older people, because phosphorus is necessary for normal bone formation, the phosphorus intake of older people is often low, and calcium supplements inhibit the absorption of phosphorus. Also, calcium bound to phosphorus is the form in which calcium in the bone is stored, and it has a much greater bone activity than other forms. Q. How much vitamin D is needed to promote strong bones? A. Because vitamin D is produced when the ultraviolet rays from the sun hit skin, people who stay out of the sun, wear sunscreen, or live in a northern latitude (such as Boston or Seattle) where less ultraviolet light reaches the skin, are at increased risk of vitamin D deficiency. In addition, aging decreases a person’s ability to synthesize vitamin D in the skin. Results from five research trials on vitamin D found that supplementation with 700-800 IU of vitamin D per day decreased the number of hip fractures by 26%, but 400 IU per day was ineffective. In addition to enhancing bone health, vitamin D improves nerve and muscle function in older people, thereby reducing their chances of falling down. Supplementation of elderly women with 800 IU of vitamin D per day has been shown to decrease the number of falls by about 50%. Q. Is that much vitamin D safe? A. The Food and Nutrition Board of the Q. Why would nutrients besides calcium and vitamin D is important? A. Bone is living tissue, constantly remodeling itself and engaging in numerous biological functions. Like other tissues in the body, bone has a wide range of nutritional needs. The typical refined and processed American diet has been depleted of many different vitamins and minerals, some of which play a key role in promoting bone health. Not getting enough of one or more of these micronutrients may be and important contributing factor to the modern epidemic of osteoporosis. In addition, supplementing with calcium may cause a loss of magnesium, zinc, silicon, manganese, and phosphorus, unless these nutrients are also provided. Q. What nutrients besides calcium and vitamin D promote healthy bones? A. Magnesium, zinc, copper, manganese, vitamin K, boron, strontium, silicon, folic acid, vitamin B6, vitamin B12, phosphorus, and vitamin C have all been shown to play a role in bone health. Following is a brief description of the role that each of these 15 nutrients play in building healthy bones. Calcium: A component of the mineral crystals that make up bone. Vitamin D: Enhances calcium absorption, prevents falls by improving nerve and muscle function. Magnesium: Important for bone mineralization (accumulation of minerals which form bones). Magnesium deficiency is associated with abnormal bone mineral crystals in humans. In an open clinical trial, magnesium supplementation increased bone mineral density by an average 5% after 1-2 years in postmenopausal women. Copper: Laboratory research has found that copper promotes bone mineralization and decreases bone loss, and that osteoporosis can develop if the diet is deficient in copper. Western diets often contain less copper than the amount recommended by the National Academy of Sciences. In a 2-year double-blind trail, copper supplementation reduced bone loss by 90% in middle-aged women, compared with a placebo. Zinc: Like magnesium, zinc is important for bone mineralization, and also has been shown to decrease bone loss. Low dietary zinc intake was associated with increased fracture risk in a study of middle-aged and elderly men. The zinc content of the diet is frequently low; a study of elderly low-income people found they were consuming only half the Recommended Dietary Allowance for this mineral. Manganese: Plays a role in the creation of the connective-tissue components of bone. Manganese deficiency in laboratory tests resulted in low bone mineral density and weak bones. Manganese deficiency may be associated with the development of osteoporosis. Boron: Supports creation of bone-protecting hormones such as estrogen, testosterone, and DHEA. Boron supplementation prevented bone loss in experimental studies. In human volunteers consuming a low-boron diet, boron supplementation decreased urinary calcium excretion by 25-33%, a change that may indicate reduced bone loss. Silicon: Plays a role in the synthesis of the connective-tissue components of bone. Silicon deficiency has been associated with bone abnormalities. In an observational study, higher dietary silicon intake correlated with higher bone mineral density. In a clinical trial, administration of an organic silicon compound increased bone mineral density of the femur (or thigh bone) in postmenopausal women. B vitamins (folic acid, vitamin B6, and vitamin B12): These three B vitamins have been shown to lower blood levels of homocysteine, a breakdown product of the amino acid methionine. An elevated homocysteine concentration is a strong and independent risk factor for fractures in older men and women. Homocysteine levels increase around the time of menopause, which may explain in part why bone loss accelerates at that time. In a 2-year double-blind trial, supplementation of elderly stroke patients with folic acid and vitamin B12 reduced the number of hip fractures by 78%, compared with a placebo. Strontium: This trace mineral is incorporated into bone and appears to increase bone strength. It also stimulates bone formation and inhibits bone breakdown. Controlled trials have demonstrated that strontium supplementation of postmenopausal women increases bone mineral density and decreases fracture risk. Vitamin K: Best known for its effect on blood clotting, vitamin K is also required for the creation of osteocalcin, a unique protein found in bone that participates in the mineralization process. The amount of vitamin K needed for optimal bone health appears to be greater than the amount needed to prevent bleeding. Vitamin K levels tend to be low in people with osteoporosis. In randomized clinical trials, supplementation of postmenopausal women with vitamin K prevented bone loss and reduced the incidence of fractures. Q. Which form of vitamin K is best? A. Two forms of vitamin K compounds are present in food: vitamin K1 and vitamin K2. Vitamin K1 (also called phylloquinone) is present in leafy green vegetables and some vegetable oils, and vitamin K2 is found in much smaller amounts in meat, cheese, eggs, and natto (fermented soybeans). To make things a little more complicated, Vitamin K2 itself can occur in more than one form. The two most important to this discussion are menaquinine-4 (MK-4, also called menatetrenone), which is licensed as a prescription drug in Research suggests that MK-7 from natto may be an ideal form of vitamin K. The biological activity of MK-7 in laboratory studies was 17 times higher than that of vitamin K1 and 130 times higher than that of MK-4. After oral administration, MK-7 was better absorbed and persisted in the body longer, compared with MK-4 and vitamin K1. Although both have shown ability to prevent osteoporosis in laboratory research, a much lower dosage (600 times lower) of MK-7 is required, compared to MK-4, to obtain beneficial effects. Thus, MK-7 has greater biological activity, greater bioavailability, and possibly more potent effects on bone, compared with other forms of vitamin K. The potential value of MK-7 for bone health is supported by an observational study from Q. Why is strontium so important in building strong bones? A. Strontium is of great interest to bone health researchers and has been studied in very high doses. Surprisingly, lower doses are not only safer for long-term supplementation, but may in fact have a greater impact on bone health than very high doses. Too little, and bone density is impaired; too much and health may be impaired. This is a case where dosing needs to be just right for optimal impact. Therefore, until more is known, it is wise to keep supplemental strontium at less than 6 mg per day. Q. Can people taking osteoporosis medications also take bone-building nutrients? A. Because nutrients work by a different mechanism than osteoporosis drugs, nutritional supplements are likely to enhance the beneficial effect of these medications. Calcium or other minerals may interfere with the absorption of biphophonates such as alendronate (Fosamax) or etidronate (Didronel). For that reason, calcium and other minerals should be taken at least two hours before or two hours after these medications. Also, it is always best to discuss the supplements you are using with your healthcare practitioner to create an integrated health plan. Final thoughts… Bone health ramifications extend beyond osteoporosis and fractures. Bone health is essential for freedom of movement, safety, comfort, independence and longevity. Weak bones do not heal well – sometimes they never heal at all. Osteoporosis-related fractures rob us of our mobility and consign thousands of Americans to walkers and wheelchairs every year. In fact, 40% of people are unable to walk independently after a hip fracture, and 60% still require assistance a year later. The most terrible consequence of fractures related to osteoporosis is mortality. The impairment of the ability to move around freely can cause pneumonia and skin damage leading to serious infections. It is estimated that suffering a hip fracture increases the risk of dying almost 25%. Making bone health a priority now will allow you to reap health dividends for many years to come.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1523) Osteoporosis, Calcium and Magnesium
Date:
April 20, 2007 12:06 PM
Consider the following: what country has the highest rate of pasteurized milk consumption? USA Today reports that more than 45 percent of Americans, aged four years and older, drink milk. Now, what country has the highest calcium supplement consumption? America. So, America must have the lowest occurrence of osteoporosis, calcium loss and bone fragility. Right? Wrong! We have the highest rate! Why? Excess calcium combined with low magnesium. One research study concludes that neither milk nor a high calcium diet appears to reduce the risk of osteoporotic hip fractures in postmenopausal women. Another study concluded that findings “do not support the hypothesis that higher consumption of milk or other food sources of calcium by adult women protect against hip or forearm fractures.” On the other hand, a recent double-blind trial conducted by Yale University School of Medicine found that magnesium significantly increased bone mineral content of the hip bones of girl’s ages 8 to 14 years. It is magnesium that will handle a calcium deficiency as well as the lack of adequate magnesium, and it will dissolve excess calcium from the body while helping any needed calcium to assimilate. Today we have diets dangerously low in magnesium. Factor in the recent addition of nutritional calcium via supplements and food fortifications that are meant to stave osteoporosis, and many of us are getting inadequate magnesium plus too much calcium. Magnesium is crucial to increasing bone mass, since it is magnesium that allows calcium to assimilate. People taking supplemental calcium should accompany their calcium with the magnesium necessary for absorption. Women taking calcium supplements to ward off osteoporosis, with out adequate magnesium nutrition, can further exacerbate the effects of a magnesium deficit. (Calcium supplements taken without sufficient magnesium can actually LOWER the bone mineralization process.) Magnesium is as important as calcium in the prevention of osteoporosis and is vital to increase bone mass.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1522) Growing Older, Feeling Better
Date:
March 28, 2007 02:15 PM
Growing Older, Feeling Better Not long ago, when a man turned sixty-five, he became officially old – the best years of his life far behind him. The milestone meant his working days were done and if he was lucky, he might get four or five years to spend as he wished before illness and infirmity set in. It was simply expected and accepted that the older a man got, the sicker he got. Well, not anymore. Today, a man age 65 is just as likely to be found hiking in the hills, running in a marathon, or even dancing in the streets than rocking in that proverbial front porch rocker. Because it’s becoming more and more evident that the older a man gets, the healthier that man has been. Eating healthy, exercising, and kicking harmful habits (like smoking) can add years to a man’s life. Aging research is proving over and over again, that we can prevent and delay heart disease, cancer, diabetes, and Alzheimer’s disease – the major causes of disability and death in men over 50. Now, it’s very true that good clean living from early on is preferable to sixty five years of bad habits and five years of good. But it’s also true that it’s never too late for men to make changes and vow to take better care of themselves. And one of the easiest and most effective ways men can improve their health is the addition of high quality nutritional supplements. In this issue of Ask the Doctor, we’ll talk about specific dietary supplements that have been scientifically shown to improve the health of men over fifty, prevent the diseases that often strike at this crucial time in men’s lives, and actually slow the aging process. Q. I just turned 50 and I’d like to begin taking nutritional supplements, but they seem so confusing. Where should I begin? A. Many men feel the same way. There are literally hundreds and hundreds of nutritional supplements on health food store shelves. Figuring out which supplements provide the best health benefits for a 50+ man can be overwhelming.
The best foundation supplement is a high quality multivitamin. Research is repeatedly finding that even very healthy men who take daily multivitamins can significantly improve their health. In fact, an article published in the Journal of the American Medical Association (JAMA) recommends that all adult Americans take a vitamin supplement. Look for solid doses of vitamin supplement. Look for sol doses of vitamins and especially minerals. Multivitamins designed to be taken once a day are often woefully deficient in calcium, magnesium, and potassium. The only mineral a man should avoid is supplemental iron. Iron should only be in formulas for women prior to menopause. Men over 50 get all the iron they need from food and too much iron can cause health problems. Look for men’s multivitamins that contain lycopene in the formula. Lycopene is the pigment that makes tomatoes red. The redder the tomato, the more lycopene is present. Numerous studies have shown that when men have high lycopene levels in their blood, they have a much lower risk of heart disease, age-related macular degeneration (a leading cause of vision loss) and prostate cancer. Other important considerations are antioxidant blends, especially fruit- and tea-derived extracts; ginseng for energy and stamina; and digestive enzymes to aid in absorption and compensate for age-related decreased enzyme levels. In fact, years of research has shown the foods a man chooses to eat (or not to eat) can have a profound impact on the health of his prostate gland. Because of this close nutritional link, prostate cancer may be the most preventable type of non-smoking related cancers. Q. Aside from taking a quality multivitamin for general health, what nutritional supplements prevent and treat prostate cancer? A. Six vital and all-natural nutrients can prevent prostate cancer from developing and even help fight the disease. Calcium D-Glucarate When men are exposed to excess levels of hormones, their risk of prostate cancer increases. A natural substance found in fruits and vegetables called calcium D-glucarate (or CDG), helps men’s built-in detoxification systems get rid of these harmful excess hormones. Selenium This antioxidant has powerful effects on the prostate gland. In a recent study, researchers recruited 974 men to take part in a large clinical trial to determine if selenium could prevent cancer. The researchers found that selenium cut the rate of prostate cancer by 63%! Green Tea Green tea is the most widely consumed liquid in the world, after water. Men in Maitake Mushroom For many years, maitake mushrooms, or dancing mushrooms, have been linked to good health in those who eat them. That’s because maitakes contain an important compound called D-fraction. A recent study showed that maitake D-fraction destroyed 95% of human prostate cancer cells in lab experiments. Lycopene Promising preliminary reports demonstrate that lycopene can actually kill prostate cancer cells, so there has been an explosion of lycopene and prostate cancer research. Q. What exactly happens to men’s hormones as they get older? A. Just as women experience significant hormonal changes as they age, so do men. In fact, the term andropause has been used to describe men’s mid-life changes. Similar to menopause in women (where the decline of estrogen causes a myriad of symptoms), andropause in men signals the slow decline of testosterone, the chief sex hormone in men. While estrogen levels decline faster and more abruptly in women than testosterone levels do in men, testosterone decline can cause a number of unpleasant symptoms. These include abdominal weight gain, hair loss, reduced energy and sex drive, heart disease, and prostate enlargement. Whether a man labels these age-related changes as andropause or just the consequences of aging, most men will unfortunately experience some or all of them as their birthdays mount. Q. So, is there a supplement that can give me the hormone level of a 20 year old? A. Sadly, no, at least not yet! But there is a nutrient that can help the testosterone in a man over fifty “behave” more like a younger man’s testosterone. A study that took place at the The secret of DIM’s prostate cancer prevention is its ability to metabolize estrogen. While estrogen is generally thought of as a “female” hormone, a precise ratio of testosterone-to-estrogen is needed to maintain a man’s healthy sexual response, effective sexual function (erection of the penis and intercourse), strong bones and muscles, viable sperm, and a well-functioning prostate gland. As men enter their fifties, this ratio begins to change. When men take DIM, however, their estrogen metabolism improves, testosterone metabolism accelerates, and the unwanted conversion of testosterone into estrogen is eliminated. This results in higher testosterone levels, similar to those seen in young men. As a result, DIM may speed weight loss, reduce prostate gland enlargement (benign prostatic hyperplasia or BPH), and help men over 50 feel stronger and leaner. Some supplements on the market today contain indole-3-carbinol (I3C), a precursor to DIM. However, I3C is unstable and requires activation in the stomach to be converted into DIM. This means I3C must be taken at a much higher amount and can undergo unpredictable and undesirable chemical reactions in your stomach and colon. DIM is by far the preferred supplement. Q. What is saw palmetto? Does it reduce symptoms of Benign Prostate Hyperplasia (BPH)? A. Yes it does and very effectively too. Saw palmetto is a small palm tree native to
The prostate gland is about the size of a walnut and is located below the bladder and in front of the rectum. It wraps around the upper part of the urethra and its primary job is the production and storage of semen, the milky fluid that nourishes sperm. BPH is one of the most common health conditions in older men. Half of all men aged 40-60 and more than 90 percent in men over 80 have BPH. BPH causes the prostate gland to enlarge, putting pressure on the urethra. Men have trouble starting or maintaining a stream of urine, find they can’t completely empty their bladders, and have to urinate frequently, even during the night. They may also have episodes of uncontrollable dribbling or complete loss of urine. BPH is caused by the conversion of estrogen to a very potent form of testosterone called, dihydrotestosterone (or DHT). When prostate cells are exposed to DHT, they multiply in number and get much larger. BPH rarely improves. It most often remains the same for years or gets gradually worse. The need to continually urinate, interrupted sleep, dribbling, and loss of urine can significantly interfere with a man’s quality of life. Prescription medications that have been developed to treat BPH are only partially effective. And surgical removal of the prostate gland may result in even more persistent urinary incontinence and the inability to achieve an erection (ED). However, saw palmetto berry extract relieves the symptoms of BPH by inhibiting the production of DHT. And, in study after study after study, saw palmetto caused none of the side effects that happen with prostate surgery or medications. Q. There seem to be plenty of ads for supplements that claim they make men into Sexual Superheroes. Is there an “honest” nutritional supplement to help me sexually? A. That’s a very good observation. And yes, there are honest nutritional supplements for men’s sexual health. Sexual intimacy is an important, complex, and lifelong need. It makes us feel better physically and mentally and adds to our sense of security, belonging, and self-esteem. But just like other changes that happen to men as they get older, men’s sexual response most often changes, too. Declining testosterone levels, changes in blood flow to the penis, certain medications that older men are prescribed, and the presence of diabetes or heart disease can all affect men’s ability to engage in sexual activity. When men have a chronic inability in obtaining and/or maintaining an erection, it’s called erectile dysfunction (ED). While ED is not an inevitable part of getting older, it does occur more frequently as men age. About 5% of 40-year-old men have ED, but more than 23% of 65-year-old men have difficulty maintaining erections. The development of prescription medication Viagra (sildenafil citrate) has revolutionized ED treatment. When a man is sexually stimulated, Viagra helps the penis fill with enough blood to cause an erection. Like all medicines, Viagra can cause some side effects, including headache, flushing of the face, and upset stomach. But because Viagra is a prescription medication, it requires a visit to a licensed healthcare practitioner. For many men, telling anyone (even a professional) that they are having trouble getting or keeping an erection is simply too embarrassing. Viagra is also fairly expensive and many older men do not have prescription drug health insurance. These reasons may explain that while an estimated 30 million men in the United States – 10% of the male population – experience chronic ED, as few as 5% of men with chronic ED seek treatment. Not every man can take Viagra, either. Men who use nitrate drugs, often used to control chest pain (also known as angina), must not take Viagra. This combination can cause their blood pressure to drop to an unsafe or life-threatening level. Men with serious liver and kidney problems who take Viagra must be monitored closely for possible serious side effects. The good news is there is a nutritional supplement that’s formulated with vitamins, herbs, and glandular products that targets male sexual organs. The formula contains vitamin E, liver fractions, wheat germ, beta-sitosterol, and herbal extracts of muira puama, Mexican damiana, saw palmetto, cola nut, ginseng, and ginkgo biloba. Vitamin E is a powerful antioxidant and men’s testicles, adrenal glands, and pituitary glands need high levels of this fat-soluble vitamin for proper functioning. Extracts of Muira puama, Mexican damiana, and cola nut have been studied for their beneficial effects on male hormones. Study of ginkgo in sexual response came about when a patient in a nursing home who was taking the herb for memory enhancement noted that his erections were improved. Since then, study of ginkgo has shown it helps blood flow to the penis. Sexual response research in one ginkgo study showed that 76% of men taking ginkgo experienced improved sexual desire, erections, and orgasms. While other nutritional supplements sold to improve sexual stamina often make outrageous claims, reputable manufacturers rely on science and results to sell their products. An important note Most often sexual problems are simply part of the aging process. They can also be signs of serious health problems. If the use of nutritional supplements for two months does not improve your erections, you do need to see your healthcare practitioner. Almost all practitioners understand how difficult this problem is for men to discuss and are experienced in getting the information as quickly and as painlessly as possible. Conclusion No man has the power to stop the passage of time. But every man has the power to make aging more healthy and less harmful. Research conducted on men who live to be 100 and beyond, has determined that those who reach extreme old age do so by avoiding ill health, rather than by enduring it. As I like to remind my patients, “Age is not determined by years, but by function.” And it’s never too late for men to detour around the major illnesses of getting older. With good nutrition, healthy habits, and high quality nutritional supplements, the best years of a man’s life can absolutely and positively be those he spends in his 70s, 80s and even his 90s.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1502) CoQ10 for Heart Health
Date:
March 28, 2007 12:39 PM
CoQ10 for Heart Health
More than 40% of all deaths in the
One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. For what health conditions is CoQ10 used?
A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.
Q. Why is CoQ10 especially important to heart health?
A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.
Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.
Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.
In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.
Q. What studies support this fact?
A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?
A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.
The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.
Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?
A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.
While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?
A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:
1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.
2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.
3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at
4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.
Q. How much CoQ10 should I take?
A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.
CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What are some other heart-friendly supplements?
A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.
Q. What supplements support healthy blood pressure and cholesterol?
A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.
Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.
The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.
Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1501) Peppermint Oil for IBS
Date:
March 24, 2007 11:01 AM
Irritable bowel syndrome (IBS) is a painful and frequently frustrating disorder of the intestines that’s often difficult to treat. Fortunately, there are scientifically studied natural products that effectively reduce the distressing symptoms of IBS. Q. What is IBS? A. IBS causes crampy pain, gassiness, bloating, and alterations in bowel habits. IBS is termed a functional disorder, because when the colon is examined, there is no visible sign of disease. While IBS causes significant pain and distress, no actual damage is occurring in the intestines. There is a wide variability in IBS. Symptoms may be mild and fairly well tolerated. Or, the pain, discomfort, and bowel dysfunction may be disabling, limiting social interactions, employment, or travel.
While some individuals with IBS have diarrhea (frequent, loose stools with an urgent need to move the bowels), others have constipation (hard, infrequent stools that are difficult to pass). And, still others may experience both. Individuals with IBS also may have painful abdominal cramps and feel an urgent need to move the bowels, but are unable to do so. A. The small intestine receives digestive material from the stomach and delivers it to the large intestine (colon). About two quarts (2,000 ml) of digestive material enter the colon from the small intestine every day. The colon absorbs water and salts from the material, which is progressively moved through the colon. This progressive movement continues until most of the fluid and salts are absorbed into the body and stool is formed. The stool passes to the left side of the colon, where it is stored until a bowel movement occurs. Because researchers haven’t been able to find actual damage in the colon, it once was suggested that individuals with IBS have emotional problems or are overly susceptible to stress. While stress may cause symptoms of IBS to intensify, it doesn’t cause the condition. Recent study has determined the colon muscle of an individual with IBS spasms after only mild stimulation. It’s thought the symptoms of IBS are produced by hyperactivity of the intestines. In other words, the intestines of individuals with IBS are more reactive to stressors and diet than usual. Almost everyone has experienced abdominal queasiness in response to everyday stress or certain foods. This may result in a brief bout of diarrhea or an upset stomach. However, this response is exaggerated in individuals with IBS. Q. How prevalent is IBS?
A. IBS is very common. In fact, it’s one of the most frequent problems seen by family physicians. It’s the most common disorder diagnosed by gastroenterologists (physicians specializing in the treatment of digestive disorders). The overall prevalence rates range from 10% to 20% of the general population in most industrialized countries. As a result, the pain and disabling symptoms associated with IBS result in significant socioeconomic costs, as wall as reduction in quality of life for many individuals. A. Normal bowel function varies from person to person. Some people move their bowels daily, while others may only have two to three stools a week. A normal bowel movement is soft, formed, and is easily passed without cramping or pain. IBS, however, causes abdominal cramps and pain, which are often severe and disabling. Bowel movements may be irregular and alternate between diarrhea and constipation. The diarrhea may be quite loose and watery. Mucous may be passed. There is often much straining, urgency, and feeling of incomplete evacuation (emptying). Abdominal bloating and passing of gas is common. Nausea, lack of appetite, heartburn, and belching may also be present. Sleep may be disrupted resulting in fatigue and lack of energy. Understandably, persons with IBS often feel anxious and depressed. Diagnosis of IBS is usually based on the continuous presence or recurrence of these symptoms for at least three months. Other intestinal conditions must be ruled out. These include Chron’s disease, ulcerative colitis, inflammatory bowel disease, colon cancer, inflammatory conditions of the stomach or pancreas, ulcers, infectious disease, or gastroesphageal reflux disease. Q. Are there clinically demonstrated natural alternatives to the over-the-counter drugs prescribed by my doctor? A. Yes, both enteric-coated peppermint oil and clown’s mustard (in combination with other herbs) have significant scientific research behind them. Both have been demonstrated to benefit individuals with IBS. Q. What is clown’s mustard and what does it do? A. The scientific name for clown’s mustard is Iberis amara. Other names for this herb are wild candytuft and bitter candytuft. Clown’s mustard is a white-flowering plant from Spain, where it grows in dry soil on hillsides and in cornfields. It is also grown in Britain, France, and the United States. Iberis amara is a member of the Brassicaceae family. Iberis refers to its place of origin, the Iberian Peninsula. Amara means bitter. The key components of clown’s mustard are glycosides and flavonoids that have specific actions on gastrointestinal tract tone. Q. Is there scientific evidence that clown’s mustard benefits people with IBS? A. There has been very impressive research on clown’s mustard (in combination with other herbs). And, it has been used with great success in Germany for many years to treat IBS and other gastrointestinal diseases. In a study of an herbal combination containing clown’s mustard, 20 patients were given the herbal combination for three to 32 days. They all had been diagnosed with chronic functional disorders for at least one to 20 years. The symptoms the patients experienced included pressure and pain in the abdomen, belching, heartburn, vomiting, nausea, fullness, lack of appetite, constipation, and diarrhea. The patients have been treated for their problems with a variety of antacids, anti-spasmodic agents, and motility-inducing substances. For the purposes of the study, the patients stopped taking these medications and received treatment only with the herbal combination. Abdominal pressure and pain in the abdomen was the most common of all the experienced symptoms, with 11 of the patients rating it as severe. After six days of treatment, only sic of the patients continued to rate their abdominal pain and pressure as severe. After two weeks, this symptom had completely resolved for 16 of the patients. Diarrhea had been rated as severe in five of the patients. By day 14, only one patient continued to have moderate diarrhea. Medications prescribed and taken for cardiovascular diseases, arthritis, and autoimmune diseases often cause gastrointestinal problems. Because these conditions are chronic, these medications must be taken for a long time, often for life. With long-term use, these medications can cause erosion of the stomach lining and actual ulcers. Many of these medication-caused symptoms are similar to IBS symptoms: pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Most, if not all, of the individuals who have gastrointestinal problems caused from medications experience two or more of these IBS symptoms. Forty patients who were taking medications for various types of cardiovascular disease and arthritis, and who are experiencing gastrointestinal problems related to their medications, were enrolled in a study. These symptoms included pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Twenty patients received clown’s mustard combined with other herbs that support gastrointestinal motility. Three days after the trial started, a significant improvement of all s symptoms was noted in those taking this combination. By day 14, abdominal pressure and pain, nausea, and heartburn were completely eliminated in the herbal combination group. Several other clinical trials that were conducted in Germany report similar results. Q. How does this herb compare to prescription drugs? A. A study compared clown’s mustard (combined with other herbs) to Reglan (metoclopramide), which is frequently prescribed to reduce the symptoms of IBS. While metoclopramide is a very effective medication, it also has numerous side effects. Metoclopramide can cause fatigue, anxiety, agitation, jitteriness, insomnia, yellowing of the skin or eyes, changes in vision, hallucinations, and seizures. Because of these serious side effects, metoclopramide must not be taken longer than 12 weeks. In comparison study, 77 subjects were randomized to receive treatment of either clown’s mustard in a combination with other herbs, or metoclopramide. All subjects had pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. The subjects took 20 drops of their assigned treatment after meals three times daily. The duration of treatment was one to two weeks. In both groups, a parallel improvement of all symptoms was observed. At no point in the study was a statistically significant difference in symptoms found. Both treatments significantly reduced pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. In short, both metoclopramide and the clown’s mustard herbal combination worked well at reducing the symptoms of IBS.
However, side effects occurred more frequently and severely in the metoclopramide group. Given the lack of differences noted between the products at reducing symptoms of IBS, it would seem sensible to choose the treatment with the fewest reported side effects and no limits on duration of use. A. Peppermint oil has been shown to relax intestinal smooth muscle. In Great Britain, peppermint oil is currently being prescribed for IBS by physicians and it has been used as a digestive aid and to soothe upset stomachs for generations. Peppermint oil has also been studied for use in an important examination of the colon. A colonoscopy is a procedure of viewing the interior lining of the large intestine (colon) using a colonoscope, a slender, flexible, hollow, lighted tube about the thickness of a finger. A study published in the New England Journal of Medicine supports the idea that even people who are not at risk for colon cancer should have this test. The American Cancer Society recommends that men and women at average risk of colon cancer should have a colonoscopy every 10 years, beginning at age 50. During a colonoscopy, individuals are sedated and almost no discomfort is experienced. The insertion of the colonoscope into the rectum and up through the colon causes some spasming. This is a natural and expected event and the physician performing the exam administers medications that effectively reduce the spasms. A recent study compared the use of peppermint oil and commonly used medications to reduce the colonic spasming in colonoscopy. The peppermint oil was introduced directly into the colon. Effective reduction of colon spasming was observed in 88% of the patients. In a critical review and meta-analysis of peppermint oil for irritable bowel syndrome published in The American Journal of Gastroenterology, eight randomized controlled trials were identified. The studies collectively showed peppermint oil is superior to placebo in improvement of the symptoms of IBS. Because of the good results of these trials, the authors of the review urged additional study of peppermint oil in IBS. However, straight peppermint oil is rapidly absorbed into the blood stream from the stomach. In recent studies comparing enteric-coated peppermint oil capsules and non-enteric coated oil, both preparations provided effective symptom relief. However, the studies concluded the enteric-coated capsules delivered the benefit of the peppermint oil directly to the intestines. In the treatment of IBS, enteric-coated supplemental peppermint is most definitely preferred. In fact, an enteric-coated peppermint oil capsule containing rosemary and thyme is extremely effective in the treatment of IBS. All three of these oils are classified as volatile oils, derivatives found in plants that impart taste and aroma. The combination of peppermint, thyme, and rosemary oils in enteric-coated capsules provides significant relief in IBS-related pain. Q. Can clown’s mustard and other herbs be taken with enteric-coated peppermint oil? A. Yes, peppermint oil capsules and clown’s mustard can be used together. However, depending on the symptoms, individuals with IBS may want to start with one supplement and then add the other if needed. Q. How do consumers find these formulas? A. Fortunately, herbal combinations containing clown’s mustard and enteric-coated peppermint oil capsules are both available at health food stores, natural product supermarkets, pharmacies, and from health professionals. Most knowledgeable sales personnel and health professionals can direct consumers to the most effective products. Q. What should customers look for when purchasing peppermint oil? A. As mentioned before, enteric coating of the peppermint oil is extremely important. The coating prevents the oil from being absorbed in the stomach. The enteric coated-capsule moves through the stomach to the small intestine and eventually to the colon, where it is released for maximum benefit. Q. What is the dosage for peppermint oil? A. The German Commission E approved peppermint oil for the treatment of irritable colon. In enteric-coated form, the Commission E recommends 0.6 ml per day. Enteric-coated peppermint capsules are available. Q. Are there side effects or other contraindications? A. Sometimes, the enteric-coated peppermint oil capsules may cause a transient burning sensation in the rectum when moving bowls. Reducing the dose will correct this. Individuals who must refrain from alcohol should not take clown’s mustard in an herbal tincture, which may contain alcohol. Q. What else can IBS patients do to feel better? A. Food allergies or food intolerance may be associated with IBS. Dairy products and certain grains may trigger a painful episode of IBS. Determining those foods that initiate the problems and eliminating them from your diet can be very helpful. Many people report their symptoms occur after a meal. Hyperactivity of the intestine of IBS is the response. Often, the strength of this response after a meal is in direct relation to the number of calories and he amount of fat in the meal. Reducing saturated fat, limiting calories, and increasing fiber intake may be helpful. Stress also stimulates the intestinal hyperactivity. Relaxation training may reduce some IBS symptoms. Listening to therapeutic audiotapes, hypnosis, counseling, and biofeedback all have been shown to improve the healing response in persons with IBS. Conclusion IBS can be painful and frustrating, capable of causing much distress. While currently there is no cure for IBS, the symptoms can be managed. The pain, abdominal discomfort, and bowel problems of IBS all respond well to treatment with the use of key herbs, including clown’s mustard, and enteric-coated peppermint oil. These herbal combinations can be both effective and safe in treating IBS. Clown’s mustard and enteric-coated peppermint oil are both effective front-line natural alternatives for IBS treatment.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1494) Neurological Health and CoQ10
Date:
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases. Q. What is CoQ10? A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body. Q. Isn’t CoQ10 a supplement for heart health? A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage. Q. How does CoQ10 affect brain health? A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production. The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced. The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced. Q. What is the blood-brain barrier and why is it important? A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree. Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle. Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier. Q. If CoQ10 is made in the body, why take supplements? A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body. Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10. Q. How does CoQ10 help people with Parkinson’s disease? A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration. A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment. Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months. The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10. The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease. Q. What were the results of clinical research on Huntington’s Disease? A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease. Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness. Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10. Q. What other diseases could benefit from CoQ10 supplementation? A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s. In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health. ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation. Q. Can taking CoQ10 prevent neurodegenerative disease? A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases. Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection. Q. How much CoQ10 should I take? A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day. CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect. Q. What should I look for in a CoQ10 supplement? A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor. Conclusion CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body. All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459) Fruit and Vegetable Lightning drink mixes from Natures Plus
Date:
February 06, 2007 02:41 PM
Enjoy the Rainbow – the Color Wheel of Fruits and Vegetables
We’ve all heard the statistics, and have probably seen the signs in the produce section of our favorite grocery store: eating 5 servings of fruits and veggies a day is important,
Chances are also pretty good that we’ve also seen the newest food pyramid, encouraging Americans to “eat a rainbow of frits and vegetables.” That is, choose from the rich variety of colors for the best all-around health benefits.
In this Ask the Doctor, we’re going to look at the unique health components of different colored fruits and vegetables, and why they’re so important. Plus, we’ll learn about supplemental options, like fruit and vegetable drink mixes, for those days when our diets just aren’t that great.
Q. What’s the big deal about fruits and vegetables?
A. Well, for the main reason that they are whole foods – created by nature (or at least generations of farming) and are rich in a variety of nutrients. Processed foods can’t match the health benefits of strawberries or broccoli – items that have fiber, vitamins, and enzymes built right in.
Q. What does “eating a rainbow” of fruits and vegetables really mean?
A. This is simply an easy way of remembering to get as much color variety in your diet as possible to maximize your intake of a broad range of nutrients. The colors of fruits and vegetables are often a tangible clue to the unique vitamins and other healthy substances they contain. Getting a variety of colors, therefore, means getting a variety of the essential nutrients your body needs to stay healthy and strong.
Enjoying the Rainbow: Fruit and Vegetable Benefits:
Q. Can you tell me a little more about the healthy components of fruits and vegetables?
Let’s take a look at some of the most well-studied and important nutrients:
Quercetin is found in apples, onions and citrus fruits (also is hawthorn and other berries and apple-related fruits usually used in traditional herbal remedies and modern supplements). It prevents LSL cholesterol oxidation and helps the body cope with allergens and other lung and breathing problems.
Clinical studies show that quercetin’s main points of absorption in the body appear to be in the small intestine – about 50%. The rest – at least 47% is metabolized by the colonic micro flora – the beneficial bacteria such as Lactobacillus acidophilus and Bifidobacterium longum. You may consider adding these beneficial bacteria (found in yogurt) either through the diet or a supplemental form.
Ellagic Acid is a component of ellagitannins – dietary polyphenols with antioxidant (and possibly anticancer) properties. Polyphenols are the basic building blocks of many plant-based antioxidants. More complex phenolic compounds, such as flavonoids are created from these molecules.
Ellagic acid is found in many fruits and foods, namely raspberries, strawberries, pomegranates, and walnuts. Clinical studies suggest that ellagitannins and ellagic acid act as antioxidants and anticarcinogens in the gastrointestinal tract.
Ellagitannins are durable antioxidants, and happily, they do not appear to be diminished by processing, like freezing. This means the benefits are still strong, even in frozen packs of raspberries or strawberries, or some of the better multi-ingredient supplement drink mixes.
In scientific studies, ellagic acid also showed an anti-proliferative effect on cancer cells, decreasing their ATP (adenosine triphosphate) production. ATP is the molecule that provides the primary energy source for the cells in our bodies. In a sense, ellagic acid seems to deprive cancer cells of their fuel.
Beta-Carotene: Probably the best-known of the carotenoids, beta-carotene is converted by the body into vitamin A. Many vegetables, especially orange and yellow varieties, are rich in this nutrient. Think summer squash, yams and of course, carrots.
Beta-carotene has long been associated with better eyesight, but it has other benefits, too. In a scientific study, beta-carotene decreased cholesterol levels in the liver by 44% and reduces liver triglycerides by 40%.
Lycopene is a carotenoid mostly found in tomatoes, but also in smaller amounts in watermelon and other fruits. Clinical studies have shown that lycopene consumption may decrease the risk of prostate cancer. In fact, high intakes of lycopene are associated with a 30% to 40% reduced risk. And, as good as beta-carotene is, its cousin, lycopene, seems to be an even stronger nutrient, protecting not just against prostate cancer, but heart disease as well.
Lutein is found in many fruits and vegetables, including blueberries and members of the squash family. Lutein is important for healthy eyes, and in fact it is found in high concentrations naturally in the macular region of the retina – where we see fine detail. It is one of the only carotenoids, along with its close sibling zeaxanthin, that is found in the macula and lens of the eye.
Lutein also supports your heart, too. In a scientific study, lutein reduced atherosclerotic lesion size by 43%. In other words, high intakes of lutein may actually help prevent coronary artery disease!
Interestingly, as is the case with lycopene, cooking or processing foods with lutein may actually make it more easily absorbed.
In clinical studies, men with high intakes of lutein (and its close cousin, zeaxanthin, found in broccoli and spinach) had a 19% lower risk of cataract, and women had a 22% decreased risk, compared to those whose lutein intakes were much lower.
Vitamin C: One of the best-known nutrients out there, vitamin C keeps our immune system strong; speeds wound healing, and promote strong muscles and joints. A free-radical fighter, vitamin C prevents oxidative damage to tissues, builds strength in collagen and connective tissue, and even reduces joint pain.
Sources of vitamin C are scattered throughout the spectrum of fruits and vegetables.
Potassium: Most Americans are deficient in potassium. For the most part, it’s hard to get too much of this valuable mineral. Potassium does great things for our hearts. Higher intakes of dietary potassium from fruits and vegetables have been found in clinical research to lower blood pressure in only 4 weeks.
Many researchers believe that the typical American diet has led to a state of chronic, low-grade acidosis – too much acid in the body. Potassium helps change pH balance to a more alkaline environment in the body and increases bone density.
This was proven in the long-running Framingham Heart Study which showed that dietary potassium, (along with magnesium and fruit and vegetable intake) provided greater bone density in older individuals.
Fiber is another food component many just don’t get enough of – especially if they’re eating a “typical American diet.” Fruits, vegetables and whole grains are excellent sources of fiber. However, fiber from a good fruits and vegetable drink mix should be derived from inulin and chicory root. This soluble fiber source not only adds to the overall amount of fiber you need (25 to 38 grams a day), but also provides a nice “nesting ground” for the beneficial bacteria that populate the intestines. And, even though some fiber has a bad rap for inhibiting mineral absorption, inulin and chicory root are “bone building” fibers – they actually help the body absorb calcium.
Flavonoids are an overarching term that encompasses flavonols, anthocyanidins, and flavones, isoflavones, proanthocyanidins, Quercetin and more. They are almost everywhere: in fruits, vegetables, grains, herbs, nuts and seeds – even in the coffee, wine and tea we drink. Flavonoids are responsible for the colors in the skins of fruits and the leaves of trees and other plants.
Flavonoids have many health benefits. They can help stop the growth of tumor cells and are potent antioxidants. Additionally, flavonoids have also been studied for their ability to reduce inflammation.
Anthocyanins: High on the list of important “visible” nutrients are anthocyanins. They color fruits and vegetables blue and red.
Anthocyanins are members of this extended family of nutmeats, the flavonoids. Typically found in high amounts in berries, anthocyanins are readily absorbed in the stomach and small intestine.
As antioxidants, anthocyanins dive deep into cell membranes, protecting them from damage. IT may be one reason why the anthocyanins from blueberries are considered such an important component in battling neuronal decline, like Alzheimer’s. Blackberries, raspberries, and strawberries are also excellent sources of this flavonoids group.
SDG lignans, (short for secoisolariciresinol diglucoside) are polyphenolic components of flaxseed, pumpkin and other herbal sources. Much of the recent research surrounding lignans has focused on flaxseed. In scientific and clinical studies, lignans from flaxseed support hormonal balance and may have cancer-preventing abilities. In fact, in one study, flaxseed lignans reduced metastatic lung tumor by 82% compared to controls.
The lignans in pumpkin seed, also considered a major source, target 5-alpha reductase activity.
This enzyme catalyzes the conversion of testosterone into the more potent dihydrotestosterone (DHT). DHT, like testosterone, is a steroid hormone or androgen. Androgens are responsible for the development and maintenance of masculine sex characteristics in both men and women. Excess levels of DHT can cause serious problems with prostate or bladder health. That’s why modulation of the 5-alpha reductase enzyme is so important – it helps maintain healthy testosterone and DHT levels. By balancing the levels of these key hormones, pumpkin seed lignans provide protection for prostate and bladder cells.
In addition, pumpkin seed has been shown to modulate the enzyme aromatase. Aromatase is present in the estrogen-producing cells of the adrenal glands, ovaries, testicles, adipose tissue, and brain. Aromatase converts testosterone, an androgen, into estradiol, and estrogen.
Inhibition of the aromatase conversion can help maintain a balance of healthy testosterone levels in women, which has been shown to strengthen pelvic muscles and reduce incidence of incontinence.
In fact, a clinical study, involving a pumpkin extract in conjunction with soy, resulted in significant support for bladder health. After two weeks of supplementation, 23 of the 39 postmenopausal women enrolled in the study showed great improvement in urinary frequency and sleep. By the end of the six week study, 74.4 percent of participants found pumpkin extract safely and significantly improved “nocturnia,” that is, the need to urinate frequently at night. For individuals with 2 to 4 episodes of nocturnia prior to the stud, and 81.8% improvement was seen – also showing great improvement in sleep quality. After all, if you don’t have to wake up every couple of hours to go to the bathroom you’re bound to get better sleep.
Beta glucan: Mushrooms are intense immune-boosting powerhouses due to their beta-glucan content. Three well-studied power-house mushrooms that contribute beta glucan to the diet include maitake, reishi and shiitake.
The most significant constituents of mushrooms are long chain polysaccharides (molecules formed from many sugar units) known as beta-glucan. These huge molecules act as immunoregualtors in the human body, helping to stabilize and balance the immune system.
This includes specific support of white blood cells, or lymphocytes, the primary cells of the immune system. Lymphocytes fall broadly into three categories: T cells, B cells, and natural killer (NK) cells.
In one clinical study, 165 patients with various types of advanced cancer were given maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, and 62% of lung cancer patients. Plus, when maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.
In another clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.
And, in a scientific study of human breast cancer and myeloma cancer and myeloma cancer cell lines, shiitake compounds provided a 51% antiproliferative effect on the cells – inducing “apoptosis’ – the programmed cell death that should occur naturally.
While beta-glucan are distributed throughout the mushroom body, the beta-glucan concentrations are significantly higher in the mycelium – the interwoven fibers or filaments that make up the “feeding structure” of the mushroom.
Bioflavonoids are commonly found in bright yellow citrus fruits, including lemons, limes and oranges. They are responsible for the bright pigment found in the skin of the fruit, and are considered a “companion” to vitamin C, seeming to extend the value of the nutrient within the body.
Hesperidin is just one of the valuable bioflavonoids found in citrus. Hesperidin appears to lower cholesterol levels, as well as support joint collagen in examples of rheumatoid arthritis.
Epigallocatechin gallate (EGCG):
Polyphenols, most notably EGCG, or epigallocatechin gallate, are well-studied and powerful components of tea. EGCG has been shown to reduce colon and breast cancer risk. Green tea also boosts the immune system and encourages T-cell formation – part of the front-line defense of our bodies against sickness and disease.
Q. I’ve been seeing articles about fruits, vegetables and supplements touting “high ORAC value.” What does this mean?
ORAC is an acronym for Oxygen Radical Absorption Capacity, and is simply a measurement of antioxidant activity of nutrients. Oxygen radicals, or free radicals, are unstable molecules. They grab electrons from other cells to use for themselves, and in the process can damage them. It is believed that free radical activity plays a role in the development of many diseases such as heart disease and cancer, and also plays a role in aging.
Antioxidants help prevent this damage by “loaning out” extra electrons to stabilize free radicals/ Consider any fruit or vegetable with a high ORAC rating as having a lot of “antioxidant power.”
I know I should eat more fruits and vegetables, but it just seems so hard to get five servings a day.
The number one excuse I hear for not buying frits and veggies is that “fruits and vegetables are too expensive.” But are they really? Certainly, fresh foods that aren’t in season and have to be shipped a distance can be a bit pricey. If anyone added up how much spend on fast food, or prepackaged or processed snacks, it would probably be shocking.
Luckily, there are many ways to get your “Daily 5”. For instance, frozen fruits and veggies retain much of their nutrient profile. They can be an excellent alternative when certain foods are out of season. So too, are fruit and vegetable drink mixes – excellent supplemental sources of some of the nutrients our bodies need most.
More recently, the American
Of course, for people not accustomed to the fiber in fruits and veggies, there is some reason to think it’ll increase gas. When cell walls break down, and fiber passes through the system, it can create flatulence. Folks who eat fruits and vegetables every day generally don’t have this problem. Their systems are already accustomed to it.
For those just starting out on a better diet, however, start slowly – it helps your body adapt. Cooking vegetables can help, too, because it begins breaking down the cell walls early on.
One thing is certain, however. The “Typical American Diet” and good health are mutually exclusive. The increase in type 2 diabetes, heart disease, high cholesterol, and hypertension all point to the abuse our bodies suffer by eating diets high in fatty meats, processed sugars, and refined grains.
Q. Can I just drink fruit and vegetables drinks in place of 5 servings of fruits and vegetables?
Green drinks and fruit and vegetable drink mixes aren’t meant to replace whole foods, but they can be an excellent substitute when you’re rushed or traveling or just trying to fill everyday nutritional gaps. Their whole food ingredients absorb very easily and gently in the gut, and many of these drink mixes contain healthy doses of fiber, too.
Green drink mixes and food-based drink mixes combine many colorful fruits and vegetables and sometimes grasses in a healthy, mixable supplement assortment. While there have been many advancements in the field of green drinks, there are only a few that take the primary reason we eat into consideration: taste!
Happily, there are some companies out there with great-tasting drink mixes that also formulate based on the color concept, ensuring you get the broadest assortment of nutrients from a full range of fruit and vegetable colors to promote optimal health.
High-quality fruit and vegetable drink mixes offer the best from nature’s color wheel in a convenient and great-tasting supplement. So, the next tie you feel like taking a coffee break – try a fruit and veggie break instead. Your body and spirit will thank you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1451) For Better Heart Health ...
Date:
February 06, 2007 12:57 PM
Nutrients Every Heart Needs
High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the
Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.
In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.
Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?
A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.
A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.
Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.
Low Risk
Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.
Moderate Risk
Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.
High Risk
Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.
Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?
A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.
Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?
A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.
That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,
Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.
Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.
Q. Don’t all multivitamins work with medications prescribed to treat heart disease?
A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.
The more risk factors you have, the greater your chance of developing heart disease.
Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?
A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.
The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.
The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.
Whole Heart Nutrition
Each additional risk factor requires additional supplements or increased doses for protection from heart disease.
Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.
A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.
In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and
Research has shown that the Omega-3 fatty acids in fish oil supplements can:
-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.
-Lower the levels of triglycerides, fats in the blood that can increase a person’s
risk of dying from a heart attack, even if a person’s cholesterol levels are normal.
-Slow atherosclerosis – the growth of harmful plaque on artery walls.
Atherosclerosis develops over many years. If the plaque growth is slow and
stable, chances are low that a heart attack will result. However, rapidly growing
or unstable plaques can rupture. The body responds with inflammation, which
causes blood clots to form. These blood clots block the artery and cause a heart
attack.
-Keep blood pressure levels low. Many people have high blood pressure for years
without knowing it. That’s because it has no symptoms. Uncontrolled high
blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.
While 25% of Americans have high blood pressure, nearly one-third of these
people don’t know they have it. This is why high blood pressure is often called
the “silent killer.”
You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.
However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.
Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. Rancid fish oil is not going to help your heart at all and may actually hurt it.
Q. That leaves CoQ10. Why is it important for Jane and Earl?
A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.
CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.
Q. How does CoQ10 actually work? Has it been studied in heart disease?
A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.
In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.
The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.
Q. What if I have already been diagnosed with Congestive Heart Failure? Will CoQ10 still help me?
A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.
In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.
Q. Are some types of CoQ10 better than others?
A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.
The best CoQ10 has to meet the following criteria:
1. Must be easily absorbed during the digestion process so that it can get into the
bloodstream.
2. Must reach the mitochondria in the cell.
3. Must be proven effective in studies.
4. Must be safe and free of impurities.
Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?
A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.
Conclusion
Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.
Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”
Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1449) Betaine HCI and Pepsin
Date:
January 28, 2007 08:41 PM
Betaine HCI and Pepsin Betaine HCl is a form of HCl used as a nutrient to supplement the stomach’s own production of HCl, or stomach acid. While occasional indigestion may be a result of acid irritating tissue in the structure above the stomach known as the esophagus, a line of research suggests that the cause of this irritation may actually be less than optimal stomach acid production. Stomach acid is normally produced by the parietal cells of the stomach and the function of stomach acid is to break down food that enters the stomach into smaller fragments and nutrient components. These components move through the stomach into the small intestine where they are further broken down by digestive enzymes in the upper part of the small intestine. The individual nutrients that result from the digestion of proteins, fats and carbohydrates can then be absorbed and assimilated by the body and used for metabolism and growth. However, optimal stomach acid production is certainly a major step for the efficiency of the digestive process. Less than ideal stomach acid production prevents foods from being broken down properly and places an added burden on the remainder of the digestive process, including enzyme production from the pancreas. As mentioned earlier, the presence of optimal stomach acid is necessary for the digestion and absorption of critical nutrients. Amino acids and other peptides from proteins, minerals, vitamin B12 and folic acid are examples of nutrients that require proper levels of stomach acid for their absorption and usage. The presence of adequate acid in the stomach is also required for the conversion of the digestive enzyme pepsin. Pepsin is produced in the stomach from its precursor pepsinogen, which is secreted by cells known as chief cells, and functions to help with the digestion of proteins. Pepsin breaks proteins down into their amino acid components. Since stomach acid is essential to the process of absorbing our nutrients from food, lack of sufficient acid production may lead to decreased health and general well-being. Ideal stomach acid production is also essential for maintaining a healthy bacterial balance in the intestines. Firstly, acid production in the stomach itself provides a protective barrier that keeps the stomach environment safe. Secondarily, low levels of stomach acid can lead to improperly, incompletely, or poorly-digested food fragments that may cause an imbalance in the growth of normal bacterial flora in the intestines. Achieving the correct balance of flora is a key to maintaining proper digestive function and overall health. Research also suggests that the body’s capacity to produce stomach acid normally declines as we age. Moreover, stress and other factors may impact proper stomach acid production. Occasional heartburn, bloating, belching, discomfort, and a "sour stomach" may often result from this. Food that we eat enters the stomach through the esophagus, or food pipe. At the junction of the esophagus with the stomach is a muscular structure known as the lower esophageal sphincter (LES). When food enters the stomach for digestion, the LES normally contracts, narrowing the passageway between the esophagus and the stomach and preventing the backflow of stomach contents into the esophagus. A major trigger for the process of tightening the sphincter is the presence of sufficient stomach acid. When sufficient stomach acid is sensed, the LES will close. However, in conditions where there is a lack of stomach acid, the sphincter remains open, allowing stomach contents, including acid, to flow back through the opening, potentially creating a sense of irritation and discomfort. Adequate stomach acid production is an essential criterion for the sphincter to function properly and prevent the backflow of stomach contents.1 A recent study assessed the incidence and causes of low vitamin B12 levels in elderly patients. The researchers suggest that the incidence of decreased vitamin B12 in the elderly, based on results of some epidemiological studies, is as high as 30-40%. When they looked at the possible causes of low B12 levels in 200 individuals that they followed, they found that food-B12 malabsorption accounted for 60-70% of the cases.2 In other words dietary B12 is bound to foods, generally animal proteins. The protein is normally broken down in conjunction with acid and pepsin in the stomach. However, low production of stomach acid may decrease the efficiency of this process and vitamin B12 remains bound to the protein source, leaving it unavailable to be absorbed. The absorption of countless other nutrients may also be impacted by low stomach acid and pepsin levels. Gentian Root Gentian is an herb that is native to parts of Europe and Asia. The root has been used extensively by traditional herbalists to support digestive function due in large part to its bitter constituents. Its present day use as a therapeutic herb dates back to the Romans and Greeks, and related species have even been used in the Indian Ayurvedic system. Various traditional texts classify gentian as a bitter tonic and digestive stimulant, due to its ability to promote the secretion of digestive enzymes. The German Commission E has approved the use of gentian for digestive support, which leads to an increased secretion of saliva and digestive juices.3 Supplementation with the combination of nutrients and cofactors present in Betaine HCl Pepsin & Gentian supports the normal digestive function of the stomach and helps to ensure that the body maintains the efficiency of nutrient absorption from the foods that we eat. Gentian serves to stimulate digestive secretions in the stomach, priming it to digest the food that we eat, while supplemental Betaine HCl and pepsin provide support to the body’s innate production of these digestive factors. Safety Take 1 capsule with each meal, or as recommended by a healthcare professional. Scientific References 1. Wright, Jonathan V., MD and Lane Lenard, PhD. Why Stomach Acid is Good For You. New York: Evans, 2001. 2. Andres E, et al. Vitamin B12 (cobalamin) deficiency in elderly patients. CMAJ 2004; 171(3): 251-259. 3. Blumenthal M, Goldberg A and J Brinckmann, eds. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications, 2000.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1447) Scratching the Surface
Date:
September 19, 2006 09:12 AM
Persistent yeast infections may indicate a body out of balance. Say the words “yeast infection” to the average woman and she’ll probably start to squirm. The burning, the itching we’ve all been there. Yeast’s miseries drive millions of desperate woman to seek relief each year. Yeast infections (also known as yeast vaginitis) start when candida albicans, a naturally occurring fungus, starts growing excessively, producing itchy discomfort and a whitish discharge. Most every woman will endure a vaginal infection at least once during her lifetime, and many of these episodes will be caused by candida. (Bacteria or Trichomonas vaginalis may also be to blame; to be sure have the necessary testing done.) When yeast strikes repeatedly you should look for an underlying cause. One of the biggest is the extended use of certain prescription drugs, particularly antibiotics, birth control pills or steroids. Another is the presence of undiagnosed diabetes. If you’ve been on meds, or have other diabetes symptoms such as excessive thirst or fatigue, see your practitioner. A number of alternative health authorities—though by no means all-see recurring yeast vaginitis as part of a systemic candida infection, also called candidiasis. They believe it occurs when intestinal yeast over-growth causes the bowel wall to “leak” partially digested food and toxins into the blood, causing such symptoms as depression, digestive woes, fatigue, irritability and rashes even weight gain. The solution lies in a diet that tightly restricts sugar and other carbohydrates. To learn more www.yeastconnection.com. Ditching the itch In addition to addressing the underlying causes of persistent yeast infection you should also tame the beast where it lives. Fortunately, there are safe, natural therapies that can make life a lot more comfortable. Tea tree oil, a natural antiseptic available in both liquid and suppository form, may help, and aloe Vera gel can provide welcome itch relief. To bolster the effects of these topical treatments, some herbalists suggest taking cinnamon or the rainforest herb pau d’arco in supplemental form. Garlic, known for its antifungal properties, is another time-tested option. After disposing of the harmful critters, replace them with helpful organisms. Organic plain yogurt, both eaten and applied directly, is a good source of these beneficial bacteria, especially when you add acidophilus or other probiotic supplements. Cutting down on your sugar consumption is always a good idea no matter what, as is upping your fiber intake (Oat bran is a good source). To help keep things cool and airy, a little wardrobe management may be in order. Avoid tight, synthetic fabrics (sorry, but those cute spandex pants have just got to go) in favor of looser garments made with natural fibers, especially white cotton underwear. If swimming’s your thing, don’t spend to much time sitting around in a damp suit—change into something dry as soon as possible. If you have got an itch that won’t go away, don’t just scratch. Learning what’s really going on is the better way to experience sustained relief. –Lisa James.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1381) L-Citrulline 500mg capsules of powder
Date:
September 01, 2006 01:03 PM
L-Citrulline 500mg capsules of powder
Now Available!
L-Citrulline is produced in the urea cycle when carbamoyl phosphate is converted to Citrulline in the ornithine carbamoyl transferase reaction. When endogenous supplies of ornithine carbamoyl transferase are insufficient, supplemental L-Citrulline has been shown to support ammonia incorporation and liver detoxification of ammonia. -- Buy Citrulline at Vitanet
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1367) Digestive enzymes and Herbs
Date:
August 25, 2006 02:26 PM
Digestive enzymes and Herbs
Raw food naturally contains the proper types and proportion of enzymes to assist in its own digestion. Food enzymes are released by the action of chewing, which ruptures the foods cell membranes. Like salivary enzymes, raw food enzymes play an important role in human digestion by predigesting food in the upper stomach, where contents may site for as long as an hour before gastric secretions deign their action.
Since enzymes are essentially destroyed at 118 degrees F, most forms of cooking and industrial food preparation render food devoid of enzyme activity. This places the full burden of digestion on the body processes and reserves. In time, this burden can weaken or overwhelm an individual’s ability to process and absorb vital food nutrients. Many health professionals believe that the prevalence of cooked and processed foods in modern society makes supplementation with digestive enzymes essential. Digestive enzymes also may be a benefit to those who suffer from clinical disorders of digestion and absorption.
Consider these advantages
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1357) Magnesium May Help Reduce Inflammation…
Date:
August 03, 2006 03:39 PM
Magnesium May Help Reduce Inflammation… Taking a daily supplement of magnesium may help reduce the levels of a type of inflammation that could lead to heart disease in people with low dietary intake of minerals. According to research published in Nutrition Research (2006, Vol.26: 193-196), Magnesium intake from supplements has an impact on the likelihood of having elevated C-reactive protein (CRP), “Separate from and in addition to dietary intake.” CRP is a pro-inflammatory cytokine—a signaling molecule associated with increased inflammation. The researchers used data from the National Health and Nutrition Examination Survey 1999-2000 and focused on 10,024 people with valid measurements of both CRP levels and dietary and supplemental intake of magnesium. Among other findings, the study showed that people with a total (Dietary plus supplement) magnesium intake below the U.S. recommended daily allowance (420 milligrams for men over 20 and 320 milligrams for women over 30) were found to be 40 percent more probably to have elevated CRP levels. along with the mineral Magnesium, trace minerals are the catalysts for all the vitamins and other nutrients your body uses for developing and maintaining good health. try out one of these trace mineral supplements which supplies 250mg of Magnesium as well as 72 trace minerals.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1339) 7-Syndrom Healing and 5-HTP
Date:
June 07, 2006 03:49 PM
Boomer Breakthrough – Keeping in the Game If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves. Mood, Anxiety and Depression Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use. How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels. Serotonin the Antiaging Neurotransmitter Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients. Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period. 5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin. It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia. Pain, Per-menopause and PMS 5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants. Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability. Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller. Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety. Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain. Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1306) This Amino Acid may help your heart… and your heart’s desire.
Date:
May 24, 2006 05:45 PM
Give all to love, obey thy heart,” cries the poet, and most of us have felt the link between our hearts and our passionate feelings. In the more reasoned language of science, what connects the heart with the heat of amore is blood flowing freely through relaxed, wide-open arteries. That’s where Arginine comes in. This amino acid (protein building block) has stirred excitement because of its ability to improve blood flow. Scientists now think that one reason nuts promote heart health, in addition to their high omega-3 content, is because they provide plenty of Arginine (as do other high-protein foods such as meat, cheese and eggs), and supplemental Arginine has been linked to improvements in cardiovascular function. This nutrient is also under the microscope as a way to promote healthy sexual functioning in both men and women. Arteries Unclenched As often as we’ve heart the heart described as a pump and the blood vessels as pipes, the plumbing analogy doesn’t entirely hold. For one thing, arteries—those vessels that carry oxygen and nutrient rich blood from the heart to the body are dynamic creations, with muscular walls that can narrow or widen as needed. One of the chemicals that control this process is called nitric oxide, and Arginine plays a crucial role in nitric oxide production. Because the body can create its own stores, Arginine is classified as a non-essential amino-acid. However, scientists now think that getting a supplemental supply (in the form of L-Arginine) may be best for optimal well-being. In a well-designed multinational study, for example, men with high cholesterol who took l-Arginine experienced drops in both blood pressure and homocysteine, a substance associated with heart attack and stroke (Journal of nutrition 2/05). And a research team at UCLA believes that combining l-Arginine with such antioxidants as vitamin C and E may reduce inflammation that can lead to blocked coronary blood vessels. Ardor Enabled Arginine’s ability to stimulate bountiful blood flow supports enhanced intimacy, which is both genders depends on a fully activated circulatory system. In fact, Arginine’s effects on nitric oxide are similar to those of Viagra and comparable drugs except that Arginine “is much less dangerous,” according to nationally noted herbalist Ellen Kamhi. Men and women experiencing sexual dysfunction enjoyed greater levels of satisfaction after taking an Arginine based supplement, and the ladies reported having better relationships with their partners. What’s more, Arginine has helped infertile men by making sperm stronger and healthier. Arginine may also help keep things pumping smoothly as the gym. It promotes the release of human growth hormone, which helps muscles grow bigger, and boosts the production of creatine, which serves as a power pack for high-intensity sports. What’s more, Arginine helps the body rid itself of ammonia, a toxic byproduct of physical activity. The amino acid’s ability to enable protein creation aids not only athletes but also people recovering from wounds, including those associated with surgery and burns. (note: the herpes virus that causes cold sores thrives on Arginine; avoid supplements if your having an outbreak.) When the mind is willing but the body falls short, let Arginine unleash your potential. –Lisa James, Energy Times.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1283) Calcium Protects against pregnancy complications…
Date:
April 15, 2006 01:34 PM
Calcium Protects against pregnancy complications… Pregnant women may want to take a calcium supplement to help reduce the risk of developing symptoms related to Preeclampsia, report researchers. Preeclampsia is defined as a combination of elevated blood pressure and excess protein in the urine. Untreated, it can yield serious complications, including eclampsia, a combination of Preeclampsia and seizures, which can cause permanent brain, kidney, and liver damage in the mother, and is potentially fatal for the mother and baby. In the study, published in the American Journal of Obstetrics and Gynecology (2006, vol.194: 639-49), more than 8,300 women pregnant with their first child received 1.5 grams of supplemental calcium per day, starting prior to 20 weeks of gestation, for the duration of the pregnancy. While taking calcium did not substantially lower Preeclampsia risk, it did significantly lower risks of complications related to Preeclampsia, including eclampsia and fatalities, among others.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1250) Vitamin B-1, C prove Worthy Complementary Therapies
Date:
March 31, 2006 06:30 PM
An increasing number of healthcare experts are calling for conventional and alternative treatments to be used together, an idea supported by a growing body of research. For example, British scientists found that taking one gram of supplemental vitamin C a day for 10 weeks helped 92 adults with asthma reduce the medication they needed for symptom control (respiratory Medicine 2006; 100:174-9). Inhaled asthma drugs have been associated with severe side effects, such as bone loss, cataracts and suppressed immunity. Increasing Vitamin Intake (in this case B-1) may also prove vital to people undergoing gastric bypass surgery, an increasingly common option for obesity. The December 27, 2005 issue of Neurology reported on a 35-year-old woman who suffered numerous difficulties after gastric bypass, including fatigue, confusion and an inability to coordinate eye movement. Her condition improved after she received 100mg of intravenous B-1 every eight hours. Other supplement news: Substance abuse –and the problems it causes-may be amenable to supplementation. At a meeting of American College of Neuropsychopharmacology (12/5), researchers claimed that hospitalized cocaine addicts experienced reduced desire for the drug after taking the supplement NAC (N-acetylcysteine); they said more study is needed. In another investigation presented at the same meeting, fish oil helped reduce anger among male substance abusers, possibly reducing the risk of aggressive behavior.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1243) Acai is an exotic palm fruit from the Amazonian rain forest!
Date:
February 12, 2006 01:38 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1215) 7-Keto - Anti-Aging and Antioxidant Protection
Date:
December 18, 2005 09:44 PM
7-Keto“Anti-Aging and Antioxidant Protection” The Fountain of Youth Discovered in Wisconsin It turns out that Ponce de Leon was looking in the wrong place for the fabled Fountain of Youth. It was recently discovered – in Wisconsin! And it turns out that the Fountain of Youth isn’t really a fountain – it’s a biological compound produced in our own bodies. This compound is extremely important for the growth and development of the human body, and, as the body’s production of this substance decreases with age, the signs of aging begin to appear – weight gain, wrinkled skin, loss of muscle, loss of cognitive function, and loss of libido. This biological Fountain of Youth was discovered by Dr. Henry Lardy and associates at the Institute for Enzyme Research at the University of Wisconsin. It’s called 7-Keto™, a metabolite of a hormone produced by the adrenal glands called DHEA (dehydroepiandrosterone). Research on 7-Keto™ indicates that it may work through a number of pathways to combat the signs of aging. Helping the body maintain a healthy weight as we age greatly improves overall health and longevity and is one of the strongest benefits discovered for 7-Keto™ to date. Unfortunately, because 7-Keto™ is a metabolite of DHEA, whose levels decline as we age, so to does this wonderful, natural bio-nutrient. Scientists originally looked to DHEA for improved cardiovascular vitality, and strengthened immune and brain function3. Researchers believed that declining DHEA so profoundly impacted our bodies that it could be partly responsible for the effects of aging. They hypothesized that supplementation with DHEA could sustain hormone levels and stave off many of the degenerative changes we collectively call aging. But there was a catch. Because DHEA is converted into sex hormones, people taking supplemental DHEA would sometimes experience the frightening, unwanted side effects associated with hormone supplementation. In 1989, Dr. Lardy and his colleagues set out to solve the mystery of eliminating DHEA’s side effects by examining all of the constituents that make up DHEA. Ten long years of research unearthed hundreds of DHEA derivatives, which were developed and tested continuously, until one derivative rose above all the others – a metabolite that was incredibly bio-active and far more promising than any other substance they’d tested. That metabolite is 7-Keto™. 7-Keto™ outperformed DHEA and other metabolites in immune modulation, memory enhancement and thermogenesis and, more importantly, without any adverse side effects3. The most significant benefit of 7-Keto™ supplementation is its ability to support healthy body weight. Obesity is a major contributing factor in a number of serious medical conditions. A recent study assessed the effectiveness of 7-Keto™ on weight loss and body fat loss. Participants were divided into two groups; one group received 100mg of 7-Keto™ twice daily and the other a placebo. Both groups exercised three times per week. At the end of the study, researchers noted a statistically significant reduction in body weight and body fat only in the 7-Keto™ group. Researchers concluded that 7-Keto™ was three times more effective than diet and exercise alone in promoting weight and fat loss1,2,7. Preliminary research also indicates that 7-Keto™ may support healthy immune and nervous systems. One study measured the effects of 7-Keto™ on memory function. Subjects were given a single dose of a substance that inhibits nerve cell communication and causes shortterm memory loss. Afterwards subjects were given a single dose of 7-Keto™. Results showed that 7-Keto completely reversed the memory impairment, suggesting that 7-Keto™ supports memory retention6. Another study gauged 7-Keto™’s ability to support immune system function. Interleukin 2 (IL2) is a substance produced by T lymphocytes that causes an increase of disease fighting white blood cells. White blood cells were taken from healthy volunteers and introduced into a solution that contained 7-Keto™ for 24 hours. When the cultures were tested for heightened IL2 production. 7-Keto™ was shown to augment IL2 production by a statistically significant 68%4. NOW® 7-Keto™ is a well-researched and patented form of this amazing product that’s supplied by the Humanetics Corporation. Humanetics 7-Keto™ has been proven safe and well-tolerated in doses up to 200mg5. Research is clear, the rate at which we age can be influenced by the diet and lifestyle choices we make. One very smart choice would clearly be adding NOW 7-Keto™ to your diet. References
1) 7-Keto™: The Key to Healthy Aging – Scientific Support; Humanetics Corporation, 1999
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1036) SAMe (S-Adenosylmethionine)
Date:
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body. There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable. Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel. SAMe (S-Adenosylmethionine) SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.* SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance. As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants. Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health. SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification. SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a stabilized form. SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability. This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1019) Pregnant and eating for two...
Date:
October 21, 2005 01:36 PM
Not - Quite - Dual - Nutrition It’s time to ditch a dietary cliché often foisted on expectant moms. “try to keep in mind that you are not eating for two, you are carefully eating for one,” write Catherine Jones and prenatal nutrition expert Rose Ann Hudson in Eating for Pregnancy (Marlowe & Company), who add that pregnancy “is not a time to skip meal, eat junk food or lad up on empty calories for quick energy.” The idea is to eat a nutritious diet that allows you to gain weight gradually as your baby grows. It helps to be at a healthy weight when starting a family. Being overweight makes conception more difficult, and at least one study ahs found a link between excess maternal weight and the risk of a birth defect called cleft palate (in which the roof of the mouth is split from behind the teeth to the nasal cavity). However, dieting during pregnancy may actually program a child for obesity by rewiring the developing brain, so try to lose weight before you try to conceive. How much should you expect to gain over the course of nine months? “A lot depends on your unique circumstances and the advice of your health care provider, but in general you can anticipate adding from two to five pounds a month for the first 14 weeks and roughly a pound a week thereafter until your due date-between 25 and 35 pounds in total. That translates into roughly and extra 300 calories a day; Jones and Hudson say that more nourishment may be necessary if you are breastfeeding, extremely active or carrying more than one child. Since stress and anxiety often lead to out-of-control eating (and gaining), be sure to tend to your own emotional needs during what can be a very exhilarating, yet sometimes overwhelming, time of life. For maximum nutrition try to eat a variety of foods while avoiding anything that provokes morning sickness. Whole grains provide both steady energy (unlike sugar-fueled spikes and crashes) and B vitamins to boot. Do not scrimp on fat-your baby’s developing nervous system depends on it-but “don’t use your pregnancy as an excuse to pig out, either,” warn Jones and Hudson. Stick with such unsaturated fats as olive oil along with rich sources of omega-3 fatty acids like flax seed oil. You definitely want to indulge in those omega-3s, which appear to boost infant intellectual development. Fish is a fine source of both omega-3 and the high-quality protein needed to build your baby’s tissues, but beware: Some species such as fresh tuna, swordfish, tilefish and king mackerel, can be contaminated with mercury. Your best low-mercury bets are catfish, pollock, salmon, and shrimp. (Other good protein sources include chicken, cottage cheese, lean red meat, yogurt and milk, all organically sourced whenever possible.) Supplemental fish oil is another omega-3 possibility because “mercury is found in the muscle of fish and not in the oil,” according to OSU’s Jane Higdon, who suggests consulting your health care practitioner for advice. “If I was going to take a fish oil supplement, I’d look for one that the manufacturer is testing for PCBs (an industrial pollutant),” such as products that meet California’s Proposition 65 standards. Don’t forget to stock the fridge with fresh produce. Fruits and veggies are richly endowed with vitamins and minerals; for example, making like Popeye and downing your spinach helps ensure you get plenty of folic acid and iron. These superfoods also supply phytonutrients, substances that may actually help protect your baby against cancer even as they enhance your own well-being. Studies on the link between maternal diet and childhood cancer protection are in the early stages according to Dr. David Williams, a researcher at the Linus Pauling Institute, but he says that shouldn’t stop you from loading up on cancer-fighting green stuff. “Certainly among the vegetables the cruciferous ones (the broccoli family) are particularly valuable in protecting against cancer,” he says. “These vegetables are also a good source of fiber and vitamin C.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=862) Mother’s Little Breakfast Cup board Helpers
Date:
October 21, 2005 10:36 AM
Mother’s Breakfast Helpers It’s oft-said but still true-breakfast really is the most important meal of the day, especially when you’re expecting. To make morning eating easier while trying to do eight things at once, Jones and Hudson recommend keeping your kitchen well supplied with whole-grain versions of cereal, bread, English muffins and cereal bars (along with that old healthy-breakfast standby, oatmeal). And stocking up on yogurt, fresh fruit and soy-or whey based protein powder lets you whip up breakfast smoothies in a jif. While you’re at it, have plenty of good-stuff snacks on hand, including raisins and other dried fruits, nuts and nut butters, fruit sauces, oatmeal cookies, whole-grain pita bread with hummus, low-fat cottage cheese and hard-boiled eggs. Minor miseries like heartburn and constipation can set in as your uterus starts elbowing other internal organs out of the way. You can head off heartburn by eating several small meals throughout the day and by taking the time to eat more slowly. Don’t lie down right after eating and when you do go to bed, keep your head elevated. The fiber in all those whole grains and produce should help keep things moving along smartly in your intestines, especially if you remember to stay well hydrated; if it isn’t enough, try adding some supplemental fiber to your daily routine. Another way to ease constipation is to get adequate exercise. At one time, “it was believe that an active pregnant woman would divert blood away from her growing fetus and toward her exercising muscles, resulting in a smaller baby,” say Karen Nordahl, Carl Petersen and Renee Jeffrey’s, authors of Fit to Deliver (Hartley & Marks). Ain’t so; exercise actually helps reduce the risk of pregnancy-induced diabetes and high blood pressure while giving you more energy and helping you rebound to your pre-pregnancy weigh after delivery (just check with your health practitioner first). They recommend a program that emphasizes aerobics and exercises designed to improve your balance and strengthen your body’s core muscles’, the ones that stabilize and support your back and abdomen. Exercise is just one component of an overall healthy lifestyle. That includes the negative stuff-you know, not smoking or drinking- and the positive stuff, like yoga and breathwork to help you feel integrated and whole. If you’re new to yoga, try taking a class with a qualified instructor, preferably someone with experience in teaching pregnant women. One last thing: Enjoy this special time in your life as you await the great adventure known as motherhood.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=861) Nutrition Insurance ....
Date:
October 21, 2005 10:25 AM
All authorities agree that taking prenatal vitamins is a smart idea. Especially important nutrients include: -Folic Acid. This B vitamin helps prevent neural tube birth defects such as spina bifida, in which a malformed spinal cord can cause everything from fluid on the brain to paralysis. “The great news is that supplemental folic acid decreases the risk of neural tube defects pretty significantly,” says Higdon. “It’s recommended that women who are planning to become pregnant take a supplement that supplies 400 mcg.” Low folate is also associated with high levels of metabolic byproduct called homocysteine; it’s not clear whether high homocysteine is a symptom of folate deficiency or a cause of birth defects. To help folate control homocysteine, add vitamins B-6 and B-12 to your regimen, especially if you are a vegan.
-Iron. Iron deficiency is the most common micronutrient deficiency in the US, especially among women of childbearing age, and “has been associated with poor child development after birth along with increased risk of miscarriage and premature delivery,” according to Higdon. “Also, if you’re deficient you’ll get really tired-you get less oxygen delivered to your tissues an the baby’s” A supplement should supply 30mg; vegetarians have to pay particular attention to their iron levels. Eating foods rich in vitamin C can make it easier to absorb iron, as can eating such fermented soy goodies as tempeh and miso.
-Calcium. Building baby’s bones requires plenty of calcium; Jones and Hudson recommend getting 1200mg a day. If you are lactose intolerant-that is, you can’t properly digest milk products-they suggest you “try yogurt made with live active cultures, whose bacteria releases lactose-digesting enzymes.” Supplemental calcium is another option, preferably in gluconate or chelate form for better absorption. (Calcium can also help cut the leg cramps caused by the pressure of a growing baby.)
-Vitamin D. It doesn’t matter how much calcium you take if you’re not getting enough of the vitamin D that lets your body utilize calcium properly. “Vitamin D deficiency is increasingly common,” says Higdon, “and the RDIs (Reference Daily Intakes) might not be high enough for people who don’t get sun exposure.” Spending 15 minutes a day in the sun can restore your body’s supplies, but “the farther north you live, the longer that period in the winter you can’t make vitamin D, and it’s actually not in too many foods.” Taking 400 IU daily can make up the shortfall.
Believe it or not, iodine deficiency is a growing concern in the US as people cut back on salt, which is commonly fortified with iodine. Higdon says that most prenatal vitamins contain 150mcg.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=860)
Date:
October 18, 2005 09:35 AM
Selenium - There have been many studies showing a direct connection between selenium and prostate cancer, and most nutritionist agree, it’s hard to get enough of it on a daily basis without taking a nutritional supplement. In the now famous Clark Study, a 63% reduction in prostate cancer was found in men who received 200 micrograms of selenium from a selenium-enriched yeast containing mostly seleniumethionine. The conclusion? Eat more tuna, Brazil nuts, and sunflower seeds, and to guard against gaps in your diet, take a daily supplement containing 200 micrograms (MCG) of selenium from selenium-enriched yeast or seleniumethionine!
Another Study conducted at Stanford University found that low plasma selenium is associated with a four to five-fold increase of prostate cancer. These results support the hypothesis that supplemental selenium may reduce the risk of prostate cancer. And because plasma selenium decreases with patient age, supplementation is particularly beneficial to older men.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=844)
Date:
October 13, 2005 04:45 PM
Benefits of Total Daily Formula
All fruits and vegetables contain carotenes, the plant pigments responsible for the rich variety of colors we enjoy in the natural world. Beta carotene is the most familiar member of the carotene family. But beta carotene never exists by itself; it is always found with other carotenes in foods. We need more than just beta carotene alone. Carotenes are powerful antioxidants, which means they help reduce the body's free radical burden. Research suggests that carotenes work as a team to keep us healthy.5 Total Daily Formula provides beta carotene, alpha carotene, lutein, lycopene, zeaxanthin and cryptoxanthin from natural sources such as algal extracts, carrot oil, marigold and tomatoes (Caromix®).
Total Daily Formula uses only corn-free vitamin C (ascorbic acid). The full daily intake of 6 tablets provides an exceptionally generous 800 mg of vitamin C.
Total Daily Formula supplies ample amounts of all essential B vitamins. Vitamin B3 is given as niacin plus an extra helping of niacinamide, the non-flush form of this important vitamin. The body uses pantothenic acid (vitamin B5) to deal with stress, so the formula provides 150 mg, which is 15 times the RDA. Vitamin B6 is another B vitamin people may run short of, so 60 mg -- 30 times the RDA -- is supplied. The formula contains 800 mcg of folic acid, the vitamin now recognized by the FDA as essential for prevention of neural tube defects in unborn babies. Folic acid also helps prevent accumulation in the body of homocysteine, a metabolite of the amino acid methionine.6 A high blood homocysteine level is now considered to be a risk factor for heart disease.7
Flavonoids, also known as "bioflavonoids." are plant pigments widely distributed throughout the plant kingdom.8 Previously known as "Vitamin P," because they help reduce capillary permeability (leakiness) flavonoids are now regarded as "semi-essential" non-vitamin nutrients that benefit health in a variety of ways.9 In addition to maintaining the structure of blood vessels, flavonoids function as versatile antioxidants. Flavonoids protect vitamin C from destruction by free-radicals, helping to preserve the body's vitamin C supply.10 Total Daily Formula provides 100 mg of pure flavonoids from 112 mg of citrus extract.
Three superior sources of Calcium
Total Daily Formula contains three of the best absorbed and most effective forms of calcium available. MCHC (microcrystalline hydroxyapatite concentrate) is a naturally-derived compound composed of calcium, plus all the minerals and organic factors in living bone tissue. MCHC has been clinically shown to benefit bone health.11 Calcium citrate malate is a very well-absorbed form of supplemental calcium shown in recent research to be helpful for postmenopausal women.12,13 Calcium glycinate is chelated with the amino acid glycine, one of the most efficient mineral carriers for effective absorption.14,15
Magnesium is essential for strong bones and healthy hearts. This versatile mineral also regulates nerve function, keeps muscles relaxed and coordinates activity of over 300 enzymes in the body.16 Total Daily Formula contains 100 percent magnesium glycinate for exceptional absorption and gentleness on the intestinal tract.17 Magnesium glycinate has been clinically tested on people with severe malabsorption with excellent results.18
Total Daily Formula provides - in addition to zinc, chromium, selenium and iodine - vanadium and molybdenum. Vanadium helps maintain normal blood sugar.19 Molybdenum works as a co-factor for enzymes that help detoxify and eliminate foreign substances from the body.20
Bioperine® for Enhanced Absorption
Bioperine® is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine®. 21 Betaine HCL - supplies HCL (hydrochloric acid) to assist digestion. All natural tablet coating made of vegetable concentrate and beta carotene.
Scientific References
2. Morgan, K.J. et. al. Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition. 1985;4:195-206.
3. Lakschmanan, F.L., Rao, R.B., Kim, W.W., Kelsay, J.L. Magnesium intakes, balances and blood levels of adults consuming self-selected diets. American Journal of Clinical Nutrition 1984;40:1380-89.
4. Mertz, W. The Essential Trace Elements. Fed. Proc. 1970;29:1482.
5. Perry, G. Byers, T. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Annu. Rev. Nutr. 1992;12:139-59.
6. Landgren, F., et. al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Int Med 1995;237:381-88.
7. Clarke, R., et. al. Hyperhomocysteinemia: an independent risk factor for vascular disease. New Eng J Med 1991;324:1149-55. 8. Havsteen, B. Flavonoids, a class of natural compounds of high pharmacological potency. Biochemical Pharmacology 32(7):1141-48.
9. Middleton, E. The flavonoids. TIPS 1984; 5:335-38.
10. Roger, C.R. The nutritional incidence of flavonoids: some physiological and metabolic considerations. Experientia 44(9):725-804.
11. Dixon, A. St. J. Non-hormonal treatment of osteoporosis. British Medical Journal 1983;286(6370):999-1000.
12. Smith, K.T. et. al. Calcium Absorption from a new calcium delivery system (CCM). Calcif Tissue Int 1987;41:351-352.
13. Dawson-Hughes, B. et. al. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. New England Journal of Medicine 1990 Sep 27;323(13):878-883.
14. Albion Research Notes Vol. 4, No. 1, ©Albion Laboratories Jan,1995.
15. Ashmead, H.D. Intestinal Absorption of Metal Ions and Chelate, Springfield: Charles C Thomas, ©1985.
16. Wester, P.O., Dyckner, T. The importance of the magnesium ion. Magnesium deficiency-symptomatology and occurrence. Acta Med Scand 1992; (Suppl) 661:3-4.
17. Albion Research Notes Vol. 3, No. 1, ©Albion Laboratories, Feb 1994.
18. Schutte, S., et. al. Bioavailability of Mg diglycinate vs MgO in patients with ileal resections. Abstract 115, AJCN 1992;56(4).
19. Cohen, N. et. al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin Invest 1995; 95:2501-09.
20. Sardesi, V.M. Molybdenum: An essential trace mineral element. Nutr Clin Pract 1993; 8:277-81.
21. Bioperine® - Nature's Bioavailability Enhancing Thermo-nutrient. Executive Summary' 1996; Sabinsa Corporation, Piscataway, N.J.
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Date:
August 12, 2005 11:10 AM
Omega Man
For Men Interested in Optimal Health, Vitality and Staying Young
Scientists have discovered the key that unlocks the door to a longer life, healthy weight, optimal athletic performance, and overall well-being. That key is composed of essential fats, called omega-3 fatty acids. You need these fats to balance the effects of the male hormone testosterone. Found in flax, pumpkin seeds, and other plants, omega-3 fats are essential to well-being, vitality, and optimal fitness; yet most men are deficient in the omega-3s.
The low-fat and nonfat fads of the 1980s and 1990s taught nutrition experts a lot about the importance of omega-3 fats. As food manufacturers created one nonfat product after another, a strange thing happened- men got fatter and heart disease rates jumped.
Since then, experts at research institutions including Harvard and the National Institutes of Health (NIH) have linked nonfat diets with depression, heart disease, weight gain, and poor physical performance.
We now know that all fats are not created equal. Although some fats are indeed bad for our health, other fats are essential to overall health, vitality, and well-being. Most men, however, over consume the wrong fats- those found in processed foods and animal products- and do not consume enough of the right fats. To make matters worse, the good omega-3s are dwindling from the food supply. Food processing has stripped this important fat from our foods, making supplementation necessary.
Thankfully, Omega Man from Barlean’s Organic Oils, a new whole food concentrate for men, will help reduce the risk of some of the most deadly and common men’s health problems. All men will benefit from Omega Man. Its blend of essential fats from flax, Styrian pumpkin seeds, and other sources complement one another, providing the optimal mix of the right types of fats, which promises to promote health and vitality no matter what your age.
From the athletic pursuits of your early twenties to the health concerns of your fifties and beyond, Omega Man is an important part of a man’s healthy diet and will unlock the door to a new, more vibrant, healthier you.
Recently, we’ve begun to report on the importance of certain men’s power foods and nutrients. By putting optimal amounts of these into men’s diets, men can ensure greater health and longevity.
Super Health Blend
Omega Man’s unique blend of flax, pumpkin and other fatty acid sources is an optimal formula for men’s health and vitality.
Organic Flaxseed Oil
Barlean’s award-winning organic omega-3 and lignan-rich flaxseed oil makes up the base of this formula and provides the richest and best-absorbed source of omega-3 fatty acids available. Other popular sources of omega-3 fatty acids, such as fish oil, may contain contaminants such as mercury and industrial chemicals. Barlean’s flaxseed oil, on the other hand, comes from organic seeds grown in optimal conditions with no chemicals, pesticides, or other contaminants. You can feel safe knowing that all of Barlean’s flaxseed oil products, including Omega Man, are pure and fresh. They help you promote optimal health without polluting your body.
Lignans
In addition to omega-3 fatty acids, Barlean’s lignan-rich flax oil is one of the world’s richest sources of lignans, important plant chemicals that act like hormones in the body. Lignans have been shown to bind to existing hormones in the body, bringing your hormones into the optimal balance needed for good health. Few men consume the amount of lignans needed to promote hormonal balance, making supplementation so important.
Lignans serve in the body to block two critical enzyme systems that serve to initiate prostate cancer and benign prostatic hyperplasia. The first is aromatase, an enzyme that converts testosterone to a powerful testosterone derivative that is five times more powerful than its precursor in promoting prostatic disease. The second is 5-alpha reductase, and enzyme that converts testosterone to estrogen. Despite popular belief, estrogen is much more powerful in provoking prostate disease than testosterone. In fact, the ratio of testosterone to estrogen begins to weigh in favor of estrogen in the aging male. As testosterone levels decline with age, estrogen levels appear to remain relatively stable. Compared to younger men, the ratio of estrogen to testosterone is up to 40 percent higher in older men.
Breakthrough research is implicating the imbalance between testosterone to estrogen as a primary cause of prostate disease. Flying in the face of past misconceptions, it would actually serve the aging male to increase testosterone at the expense of estrogen. It appears that this is exactly what lignans do in blocking the enzyme necessary for converting testosterone to estrogen. When the enzyme is blocked, testosterone is spared because it is not being converted to estrogen. In what you could visualize as a seesaw-like action, the ratio of testosterone to estrogen begins to move back in favor of testosterone.
The action of lignans in sparing testosterone may hold greater implications than the obvious. Lack or loss of sexual desire in men and women is oftentimes associated with low testosterone levels. By preserving testosterone, many men and women may be able to retain or regain their sexual vigor. In fact, agents that block the conversion of testosterone to estrogen have been showing to increase testosterone levels by as much as 10 percent. (Speaking of sexuality, the surgical treatment of choice for prostatic disease (prostectomy) is the leading cause of impotency in men over 50. This fact alone should be powerful motivation for men of all ages to consider a supplemental regime to include lignans to lower the incidence of prostate cancer and benign prostatic hypertrophy.)
The full significance of a “high-in-lignan” diet may be realized by the fact that lignans have been found isolated within prostatic fluids. Analytical work performed at a prominent cancer research center has indicated that the level of lignan in expressed prostatic fluid can be remarkable high, suggesting that it could well exercise a physiologic role within the gland. The glandular cells are certainly bathed in prostatic secretion for some considerable period, during which they could well influence cell biology. It has been established that the higher the intake of dietary lignans, the higher the physiologic lignan concentration in urine, blood plasma and prostatic secretions. The inference here is that the more dietary lignans that are ingested the more protection is offered in bathing the prostate gland in fluids high in protective lignans.
Styrian Pumpkin Seed Oil
Barlean’s went to the edge of the earth to procure the seeds of a rare and unique pumpkin found only in the region of southeast Austria. It is reputed for its extraordinary wealth of vitamins A, C, E, and K and high levels of phytosterols, all important for reducing risk of enlarged prostate and in the fight again cancer and heart disease.
Phospholipid Concentrate
Nearly every part of your body, from your internal organs to your cell membranes to your brain, contains phospholipids. Phospholipid supplementation has been shown to promote heart, digestive, liver, and brain health. Omega Man contains the optimal amounts of phospholipids for your health.
Plant Phytosterol Complex
Omega man is a rich source of the plant phytosterols betasitosterol, campesterol, and stigmasterol. If men have not begun to put phytosterols into their diet, then they’re missing out on an important natural food constituent that offers protection against toe most common cancers, that is an excellent remedy for enlarges prostate, and lowers cholesterol. Phytosterols are used widely in Europe to treat enlarge prostate (benign prostatic hyperplasia) and are known to lower the risk of cardiovascular disease by interfering with cholesterol absorption. Omega Man contains an optimal blend.
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Date:
June 29, 2005 09:59 AM
Hoodia Extract - Discover the Contemporary Use for a Traditional Food Source
The San Tribesmen of the Kalahari Desert in southern Africa have known for millennia what we’ve only recently discovered; that the cactus-like Hoodia gordonii plant can be used as a healthy alternative food source. Because Source Naturals is dedicated to your good health, we’ve fused ancient San tradition with modern science to develop HOODIA EXTRACT.
The sustenance the San derived from the hoodia plant as a main food source allowed them to travel lightly without the burden of extra food to hinder their journey on long hunting trips. With the introduction of our high quality HOODIA EXTRACT, Source Naturals offers you a safe, natural solution to achieving and maintaining a healthy lifestyle, and the chance to discover the contemporary use for the powerful nutritional supplement everyone’s looking for. HOODIA EXTRACT underlines Source Naturals commitment to bringing you the highest quality dietary supplements in your steps toward good health.
An Age Old Tradition
Life in southern Africa’s Kalahari Desert could be cruel. But even without modern research, the San Tribesmen knew their nutritional needs could be met with a remarkable botanical. For more than a hundred thousand years the San thrived as hunter-gatherers; their success dependant on their ability to locate food. Their treks across the Kalahari would last for months, even years, with the men hunting for antelope, and the women foraging for what became the main staple in their diet: fruit, nuts, and plants. None of their traditional food sources were more important than the phenomenal Hoodia gordonii plant. The hoodia plant became their chief source of sustenance while roaming the desert. Fruit and meat spoiled, nuts never lasted, but the stems and roots of that plant were special.
A Special Plant
Despite its similar appearance, the cactus- like hoodia is characterized as a succulent plant, which is a member of the milkweed family. Though there are about 20 species within the family, the active ingredient of hoodia is found only in the gordonii variety. Experts in succulent horticulture have helped ensure that the material Source Naturals uses to make HOODIA EXTRACT is gathered from authentic Hoodia gordonii sources.
A Potent Extract
The secret of HOODIA EXTRACT lies in the plant’s active ingredient; a substance containing previously unknown molecules discovered by South African scientists, and found to interact with the hypothalamus. Through painstaking chemical testing to assure quality and potency, Source Naturals has gone to great lengths to develop an extract that is best for the supplemental needs of its consumers. Every bit of the certified material Source Naturals receives is put through high tech chromatographic analysis to verify the purity of the active constituents needed to make HOODIA EXTRACT.
A Responsible Company HOODIA EXTRACT has been produced with environmental sustainability in mind. Using only materials safely cultivated from the stems of seedlings grown on approved farms in South Africa, Source Naturals has made certain those materials were gathered with the knowledge and help of the San people to better preserve the Kalahari’s natural resources.
A Wellness Revolution in Nutritional Health
With today’s people faced with a multitude of nutritional problems, it is increasingly critical for us to take charge of our own well-being. Source Naturals is devoted to providing the highest quality products designed to supplement your diet and aid in your pursuit of a healthy lifestyle. HOODIA EXTRACT is available at your local health food store in 250mg capsules or tablets. Source Naturals - providing nutritional benefits offered only in the natural products marketplace.
References
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Date:
June 25, 2005 10:05 AM
GARLIC: A NATURAL IMMUNITY BOOSTER
With the arrival of new and frightening viral diseases like AIDS and flesh eating bacteria, boosting immunity is receiving new attention. Because these types of diseases have no effective cures or treatments, strengthening the body’s ability to fight off infection has become even more important.
Garlic has an abundance of sulphur containing amino acids and other compounds that seem to initiate increased activity in the immune system. For example, macrophages, which kill invading pathogens are stimulated by the presence of garlic.20 The Journal of the American Medical Association states, “it [Garlic] may become known as one of the grand conductors of the body’s immune symphony,”21 Several studies have shown that garlic stimulates immune function by making macrophage or killer cells more active. In so doing, garlic can prevent the onset of colds and fevers by increasing resistance to infection and to stress. It is common knowledge now that stress can compromise immune function. We are constantly assaulted by inadequate nutrition, cigarette smoke, physical injury, mental tension, and chemical pollution. Recently, the notion that vaccinations may also tax the immune system has emerged. In light of the enormous pressure which our immune systems sustain, supplemental nutrients like garlic are clearly needed.
Unfortunately stress, is here to stay and affects us daily through poor diets, environmental pollution and nervous tension. One study from Japan revealed that when mice were exposed to stress, their immunoglobulin production decreased making then more susceptible to infection. When Garlic extract was added to their diets before experiencing stress, their immune systems were protected to some degree.22
Another reason why garlic is such a powerful immune system booster is offered by a medical doctor. Concerning garlic, Dr. Robert Atkins, M.D. of New York City has said: “Garlic is an important nutritional food, The most reasonable explanation for its effectiveness [as a contributor of power to the immune system] is that it picks up toxic materials and transports them out of the body.”23 The food factors contained in garlic also play a role in beefing up the body’s defenses against disease. Garlic is full of nutrients including 17 amino acids. Recent studies have found that the changes which occur in the immune system when autoimmune disease is present are the same as those found in malnutrition.24 Garlic is one of the best immune system fortifiers available.
remarkable content of germanium alone offers excellent immunostimulation. In addition to germanium, Garlic contains thiamine, sulfur, niacin, phosphorous, and selenium. Mother Nature knew what she was doing when designing garlic for human consumption.
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Date:
June 24, 2005 05:15 PM
Today’s sedentary lifestyles and sugar-rich, nutrient-poor foods are contributing to the rise of obesity in our society. The result: challenges to your body’s system of balancing blood sugar levels and insulin activity. Maintaining a healthy diet and lifestyle helps keep blood sugar levels in the normal range, but sometimes you need nutritional support when you don’t have time to make those healthy food choices. Source Naturals, the science company, introduces VANADIUMW/CHROMIUM for blood sugar support. Research shows that these two important minerals help maintain normal blood sugar levels when used as part of your diet.
Vanadium works together with chromium to support healthy blood sugar levels. Research has shown that both of these important minerals play a key role in normal insulin function.
Vanadium: Balances Insulin Activity Vanadium, named after Vanadis the Norse goddess of beauty, belongs to a group of biologically important metals known as transition elements. These metals have a natural tendency to form complexes with organic compounds called coordination compounds that serve important biological functions.
Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. The sugar that remains in the blood can create problems by binding with protein molecules, resulting in damaged, non-functioning structures, in a process called glycation. Some evidence suggests that vanadium supports these vital metabolic processes because of its ability to mimic the actions of insulin.
More Absorbable Form of Vanadium
Absorption of dietary vanadium and supplemental vanadium is poor. It is estimated that less than 5% of dietary vanadium is absorbed. Organic forms of vanadium, such as bis-glycinato oxovanadium or BGOV, are recognized as being more absorbable. BGOV is an organically bound, bioavailable form of vanadium complexed with the amino acid glycine. Glycine, an amino acid found in the protein of all life forms, generates superior vanadium absorption.
Chromium: Supports Glucose Metabolism Chromium is a trace element the body needs in very small amounts, but it plays a significant role in human nutrition. Its most important function is to help regulate the amount of glucose in the blood. Insulin plays a role in this process, by regulating the movement of glucose out of the blood and into the cells. Chromium is a key constituent of the compound known as glucose tolerance factor (GTF). This mineral enhances the effectiveness of insulin, encouraging glucose to enter cells, where it can be burned for fuel.
Chromium participates in glucose metabolism by enhancing the effects of insulin. Insulin binds to insulin receptors on the surface of cells, activating those receptors and stimulating glucose uptake by cells. Through its interaction with insulin receptors, insulin provides cells with glucose for energy and prevents blood glucose levels from becoming elevated. Glucose buildup in the bloodstream is associated with adverse changes in lipid profiles and increased challenges for cardiovascular health. Some studies examining the effects of chromium supplementation on lipid profiles have observed reduction in serum total cholesterol, LDL cholesterol, and triglyceride levels. Source Naturals VANADIUM W/CHROMIUM includes ChromeMate®, a patented compound of chromium and niacin with proven GTF activity.
Wellness Nutrition
Taking responsibility for your health is at the heart of the wellness revolution. Sometimes life may seem like it’s passing you by and you may not have time to focus on staying healthy. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you products like VANADIUM W/CHROMIUM to help you maintain a healthy balance.
References:
Anderson, R.1998. Chromium, glucose intolerance and diabetes. Journal of the American College of Nutrition 17(6):548-555. Jellin, J., et al. 2004. Vanadium Monograph. Pharmacists Letter/Prescribers Letter Natural Medicines Comprehensive Database. Therapeutic Research Facility. Nandhini, S., et al. 1993. Insulin-like effects of bis-glycinato oxovanadium complex on experimental diabetic rats. Indian Journal of Biochemistry and Biophysics 30:73-76.
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Date:
June 16, 2005 10:57 AM
Bromelain Sinus Ease™
Nature's Life Sinus Products: Sinus cavities are lined with delicate mucous membranes, which act as filters for your respiratory system. Normal sinuse tissues are pink and healthy. For many people, when their sinuses come in contact with allergens, pollutants or harmful micro-organisms, histamines are released as a protective measure by the immune system. Sinuses naturally respond by becoming irritated, red, and inflamed with these healing histamines. This process, called the natural inflammatory response, helps to neutralize and remove the irritants in sinuses cavities. Sometimes, however, the immune system continues to flood the sinuses even after the irritants are removed. Bromelain Sinus Ease™ contains three ingredients that have been shown to enhance the body’s ability to reduce this natural inflammatory response and help clear up sinuses.* Bromelain Bromelain is a group of protein-digesting enzymes extracted from pineapples (Ananassa sativa). Bromelain breaks down fibrin—a key component of the body’s natural inflammatory response to allergens and other foreign stimuli.* Bromelain also appears to inhibit the natural formation of prostaglandins (hormone-like substances) that trigger the natural inflammatory response.*1 It makes mucus less thick,2 allowing the mucus to drain more easily.* Human trials have shown that by breaking down and helping to remove fibrin, bromelain reduces the discomfort of irritated tissues.*3 Double-blinded trials in patients with irritated sinuses show that the natural inflammatory response is reduced more effectively by concentrated bromelain than by placebo.*4 ,5 ,6 ,7 In all cases, a majority of people responded well to bromelain supplements.* Bromelain has also helped reduce the duration of the natural inflammatory response after nasal procedures by over 70% in a controlled trial.*8 The recommended daily amount of Nature’s Life Sinus Ease™ utilizes 1,200 mg a very high potency bromelain enzyme which has an activity of 2,880 GDU (Gelatin Digestive Units), or 4,320 MCU (Milk Clotting Units) per serving. Vitamin C also helps reduce histamine release.*9 Some studies have reported that vitamin C is useful in reducing the natural inflammatory response in nasal passages.*10, 11, 12 The effectiveness of vitamin C in reducing histamine release is still debated, however, because a controlled trial was unable to show consistent effects.*13 Doses up to 2 grams per day have been used by researchers. It may be difficult to show these effects in research trials because vitamin C appears to help only some people without affecting others.*14 Studies, however, clearly show that vitamin C supplementation can lower elevated blood levels of histamines.*15, 16 Nature’s Life adds naturally-buffered vitamin C to Sinus Ease due to its safety, immune-supporting effects and potential efficacy to reduce histamine release.* Quercetin is a bioflavonoid found in many natural foods including citrus fruits, onions, apples, tea and lettuce. As with bromelain, quercetin helps reduce the natural inflammatory response by inhibiting the natural formation of the pro-inflammatory agents, prostaglandins and leukotrienes (white blood cells).*17,18 Quercetin also helps lessen the natural inflammatory response for children with sensitivities to inhalants.*19 Additionally, quercetin may help reduce the effects of harmful micro-organisms *20 Bioflavonoids at doses of 1,200 mg per day have reduced the natural inflammatory response in human studies in combination with 1,200 mg vitamin C,21 an outcome confirmed in double-blinded research using 600 mg/day of bioflavonoids and 450 mg/day of vitamin C.*22 Substances which inhibit the natural inflammatory response rarely target just one part of the body.* While quercetin has yet to be tested in reducing the natural inflammatory response in sinuses specifically, doctors of natural medicine frequently use it for that purpose because of its proven ability to lessen the natural inflammatory response elsewhere in the body.* Nature’s Life has combined these powerful phytonutrients to make Sinus Ease™. High potency Bromelain, Quercetin and vitamin C work to inhibit the natural pro-inflammatory response and encourage adequate sinus drainage.* No safety concerns have been identified with any of these ingredients.23, 24 It is recommended to take the three capsules per day between meals. Since bromelain is a proteolytic enzyme, if taken with a meal it will act on the protein in the food rather than the natural pro-inflammatory fibrin, so remember to take it between meals.* Enjoy the winter season and find relief from allergens throughout the year! Nature’s Life Sinus Ease™ can help. References: Martin GJ. Bromelain pineapple proteases with anti-edema activity. Exper Med Surg 1962;20:228-48. Blonstein JL. Control of swelling in boxing injuries. Practitioner 1969;203:206. Seltzer AP. Adjunctive use of bromelains in sinusitis: a controlled study. EENT Monthly 1967;46:1281-8. Taub SJ. The use of Ananase in sinusitis—a study of 60 patients. EENT Monthly 1966;45:96-8. Ryan RE. A double-blind clinical evaluation of bromelains in the treatment of acute sinusitis. Headache 1967;7:13-7. Taub SJ. The use of bromelains in sinusitis: a double-blind clinical evaluation. EENT Monthly 1967;46:361-5. Seltzer AP. Minimizing post-operative edema and ecchymoses by the use of an oral enzyme preparation (bromelain). EENT Monthly 1962;41:813-7. Johnson CS, Martin LJ, Cai X. Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis. J Am Coll Nutr 1992;11:172-6. Zuskin E, Lewis AJ, Bouhuys A. Inhibition of histamine-induced airways constriction by ascorbic acid. J Allergy Clin Immunol 1973;51:218. Ruskin SL. High dose vitamin C in allergy. Am J Dig Dis 1945;12:281. Holmes HN. Hay fever and vitamin C. Science 1942;96;497. Fortner BR, Danziger RE, Rabinowitz PS, Nelson HS. The effect of ascorbic acid on cutaneous and nasal response to histamine and allergen. J Allergy Clin Immunol 1982;69:484-8. Bai TR, Martin JG. Effects of indomethacin and ascorbic acid on histamine induced bronchoconstriction in normal subjects. NZ Med J 1986;99:163 [abstr]. Holmes H, Alexander W. Hay Fever and Vitamin C. Science 1942;96:497-99. Johnston CS, Martin LJ, Xi C. Antihistamine Effect of Supplemental Ascorbic Acid and Neutrophil Chemotaxis. J Am Coll Nutr 1992;11:172-6. Middleton E, Drzewieki G. Naturally occurring flavonoids and human basophil histamine release. Arch Allergy Applied Immunol 1985;77:155-7. Welton AF, Tobias LD, Fiedler-Nagy C, et al. Effect of flavonoids on arachidonic acid metabolism. Prog Clin BiolRes 1986;213:231-42 Balabokin II, Gordeeva GF, Fuseva ED, et al. Use of vitamins in allergic illnesses in children. Vopr Med Khim (Russia) 1992;38:36-40. Ohnishi E, Bannai H. Quercetin potentiates TNF-induced antiviral activity. Antiviral Res 1993;22:327-31. Miller MJ. Injuries to athletes. Med Times 1960;88:313-6. Cragin RB. The use of bioflavonoids in the prevention and treatment of athletic injuries. Med Times 1962;529-32. Taussig SJ, Yokoyama MM, Chinen N, et al. Bromelain: A proteolytic enzyme and its clinical application. Hiroshima J Med Sci 1975;24:185-193. Hertog MGL, Feskens EJM, Holman PCH, et al. Dietary flavonoids and cancer risk in the Zutphen elderly study. Nutr Cancer 1994;22:175-84. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
DMAE
Enzymes are absolutely essential for life. These naturally occurring substances are found in the human body, animals, and plants. More than 2,700 enzymes have been identified in the body, each of which is constantly in motion. Life is made up of a series of reactions known as metabolism. Enzymes are responsible for making this process work. Enzymes are involved in every individual biochemical function that takes place in the human body. Some even refer to these substances as the spark plugs of the body. Enzymes are responsible for digesting food and destroying toxins, viruses, antigens that invade the liver and bloodstream, parasites, and worms. They also help in the destruction of free radicals before cell damage can occur. The body would deteriorate without enzymes. These substances are necessary for the production of vitamins, minerals, and amino acids being converted into vital neurotransmitters, which allows the body to function properly. 
