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Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592)

Date: December 06, 2023 04:55 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: six top-notch supplements that can help you achieve your goals.

If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.

For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before.

Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level.

For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence.

In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select.

Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery.

Oxidation and Free Radical Damage

A fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases.

Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level.

As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup).

Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease

Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being.

So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully.

Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging.

While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively.

Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery:

Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results.

BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - leucine, isoleucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair.

Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery.

Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline.

Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health

Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results.

Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein.

Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health.

In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6591)

Date: January 19, 2023 04:43 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 Reasons to Look Forward to Cooler Weather with Cocoa Lovers™ Organic Hot Cocoa

As the weather starts to cool down, there’s no better way to warm up than with a cup of hot cocoa. Cocoa Lovers™ Organic Hot Cocoa is the perfect treat for those crisp fall and winter days. Here are five reasons why you’ll look forward to the cooler months with Cocoa Lovers™ in your cupboard.

1. Crafted for Quality – Cocoa Lovers™, we believe that quality always comes first. That’s why our organic hot cocoa is made from only the best ingredients available, including premium organic Dutch-processed cocoa powder, organic sugar and natural flavors like vanilla, cinnamon and nutmeg. Everything is blended together until it forms a rich and creamy concoction that will have you coming back for more!

2. Natural Goodness – If you’re looking for something to indulge in without having to worry about putting your health at risk, then our organic hot cocoa is perfect for you. Not only is it free of artificial preservatives, colors and flavors but it also contains no added trans fats or hydrogenated oils so you can feel good about what you put into your body.

3. Versatility – Our hot cocoa mix isn't just good for making hot chocolate — it can also be used in baking recipes such as cakes, cookies and brownies! And if you're feeling adventurous, why not try adding some spices like chili powder or cardamom for a unique twist? The possibilities are endless!

4. Convenience – No need to spend hours slaving away over a stove because our organic hot cocoa mixes come ready-to-go that make preparing your drink quick and easy, you can mix it thick or thin, it tastes good both ways! Just add water (or milk!) and heat until desired temperature is reached — it's that simple!

5. Great Taste – But of course, all of this would be meaningless if our product didn't taste great — which thankfully it does! Our customers rave about the sweet yet complex flavor profile that's sure to please even the pickiest palates out there; plus, each packet makes two servings so you can share with friends or family members who may not like their drinks as sweet as yours.

So if you’re looking for an easy way to warm up during these cooler months while also indulging in something delicious without compromising on quality or nutrition value, then Cocoa Lovers'™ Organic Hot Cocoa should definitely be on your list! Whether enjoyed alone or with friends and family around the fireplace; whether stirred into cakes or cookies; whether served with marshmallows or topped with whipped cream—enjoying some hot cocoa during these chilly days has never been easier (or tastier)!

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Date: November 08, 2022 05:37 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Support Healthy Gastroinesteinal Tract, Blood Sugar, And Cholesterol With Berberine

Berberine is a substance that has been shown in clinical studies to support multiple body systems. It is found in the roots, stems, and bark of certain plants and has a long history of traditional use. Berberine supplements are a convenient way to get the benefits of this substance, and they can support gastrointestinal health, healthy blood glucose levels, and healthy blood cholesterol levels.* Let's take a closer look at the benefits of berberine.

Gastrointestinal Health

Berberine has been shown in human clinical trials to support gastrointestinal health. This is likely due to the fact that it can help regulate the growth of certain bacteria in the gut.* In addition, berberine has been shown to stimulate production of mucus, which can help protect the gut lining.*

Blood Glucose Levels

Several clinical trials have demonstrated that berberine can help support healthy blood glucose levels.* This is likely due to the fact that berberine can help improve insulin sensitivity and decrease insulin resistance.* In addition, berberine can help stimulate production of glucose-6-phosphate dehydrogenase (G6PD), an enzyme important for regulating blood sugar levels.*

Blood Cholesterol Levels

Clinical trials have also demonstrated that berberine supplementation can help support healthy blood cholesterol levels already within the normal range.* This is likely due to the fact that berberine can help decrease low-density lipoprotein (LDL) cholesterol and increase high-density lipoprotein (HDL) cholesterol.*

As you can see, there are many reasons to consider adding a berberine supplement to your daily routine. If you are looking for a convenient way to support gastrointestinal health, healthy blood glucose levels, and healthy blood cholesterol levels,* a berberine supplement may be right for you. As always, be sure to talk to your healthcare provider before starting any new supplement regimen.

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Date: October 11, 2022 03:29 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to Deal With Mild Ear Discomfort

Do you ever have that feeling like there's something in your ear but you can't seem to get it out? Or maybe your ear feels itchy and uncomfortable but you're not quite sure why. If you're experience any mild discomfort or irritation of the tissues of the ear, don't worry—you're not alone. In fact, this is a pretty common problem. But what can you do about it?

One option is to try using a natural blend of herbs like Now Foods soothing Ear Oil. This product is designed to cleanse and moisturize the delicate tissues of the ear canal, providing relief from itchiness and discomfort. Simply apply a few drops of the oil into your ear and massage gently for 30 seconds. Then, tilt your head to the side and let the oil drain out. Repeat as necessary until you're feeling better.

Another option is to make a simple home remedy using ingredients that you probably already have in your kitchen. First, mix together 1/4 teaspoon each of baking soda, salt, and hydrogen peroxide. Then, use a dropper to apply 3-4 drops of the mixture into your affected ear. Keep your head tilted for 5 minutes so that the mixture has a chance to work its magic, then rinse with warm water and dry with a clean towel.

If you're experiencing any mild discomfort or irritation in your ears, don't panic—there are a few things you can do to find relief. Try using an herbal oil like Now Foods soothing Ear Oil or mix up a simple home remedy using ingredients like baking soda, salt, and hydrogen peroxide. Whichever method you choose, hopefully you'll be feeling better in no time!

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Date: April 23, 2019 02:41 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 powerful reasons to start eating garlic TODAY

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Date: August 02, 2018 09:53 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Alkaline Water: Beneficial or All Hype?

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Date: January 22, 2018 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Say Goodbye To Gingivitis With These Home Remedies That Will Help You Eradicate It!

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Date: July 15, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How To Heal Cold Sore Naturally!!

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Date: June 29, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: hydrogen Peroxide For Teeth Whitening, Hair And More

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Date: March 14, 2017 01:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cooking With Canola Releases More Toxic Cancer-Causing Chemicals Than Any Other Type of Oil

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Date: February 28, 2017 06:19 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Anti-inflammatory diet can help many issues

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Date: February 28, 2017 05:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Anti-inflammatory diet can help many issues

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Date: January 22, 2017 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why high-dose vitamin C kills cancer cells

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Date: January 16, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: New class of hydrogen sulfide donor molecules

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Date: December 16, 2016 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Researchers develop tiny, shining crystals that detect and clean heavy metals in water

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Date: November 03, 2016 01:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why hydrogen peroxide should be in every home

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Date: September 27, 2015 08:37 AM
Author: Darrell Miller
Subject: Superoxide Dismutase (SOD) and its Protection of the Liver

SOD consists of enzymes that speed up the break-down or partition/dismutation of the superoxide (O2-) radical into its constituent molecular content Oxygen or hydrogen peroxide. Superoxide is harmful to cells and is produced as a by-product of oxygen metabolism; therefore it needs to be controlled or regulated. The resultant hydrogen peroxide is also harmful but to a less extent, and it is further broken down by other enzymes like catalase, This sums up the crucial role played by Superoxide Dismutases (SOD) as an important antioxidant in almost all living organism exposed to oxygen.

SOD extracted or laboratory manufactured can be used as a medicine orally or taken as an injection. When taken orally it is believed to remove wrinkles, rebuilding tissue, and prolonging life; even though it is not proven that orally administered SOD is absorbed by the body. When injected it functions as a painkiller, treatment of inflammation caused by sports injuries, osteoarthritis, kidney condition known as interstitial cystitis, gout, cancer, lung problems in infants among others.

A critical role played by SOD IS the protection of the Liver; which is one of the most crucial organ in the body for it is engaged in high-level metabolism in its function of detoxifying chemicals, breakdown of drugs and conversion of certain food into necessary nutrients for the body. These processes entail the high use of oxygen needed by the liver cells in the effort to function optimally and thus the production of the harmful Superoxide as a by-product. SOD as an enzyme helps to break down this harmful by-product that is potentially harmful to the liver cells and consequently prevent tissue damage.

SOD also prevents oxidative tissue damage of the liver as the result of strenuous exercise. Exhausting exercise or running causes a significant surge in the activities of glutathione peroxidase (GPX), and xanthine oxidase (XO), and in addition to increased levels of thiobarbituric acid-reactive substances (TBARS) in liver tissue immediately after the activity. Scientific studies have revealed that effective protection of the liver against such oxidative damages requires increased dosage of the antioxidant SOD.

Reference:

//www.ncbi.nlm.nih.gov/pubmed/8820884

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Date: August 16, 2015 07:14 PM
Author: Darrell Miller
Subject: What is the Krebs cycle and why is it important?

The Krebs cycle is a series of chemical response that helps in the production of Adenosine triphosphate (ATP) and carbon dioxide, a compound that is rich in energy.  This cycle happens with the combination of two carbon coenzymes and carbon complexes and goes through a series of changes to produce the required energy that is needed for the smooth functioning of living organism.  This cycle occurs in all the cells that use oxygen for their respiration process.  Carbon dioxide has an important role since it fuels breathing and the ATP also plays a vital role as it provides cells with a required energy for synthesis of proteins from amino acid and the reproduction of deoxyribonucleic acid.  These are considered essential for energy supply and for the continuation of any kind of life including human.

The Krebs cycle is known as the second phase of the aerobic respiration.  Aerobic respiration is composed of three phases, Glycosis is the first phase, followed by the Krebs Cycle, and last is the Electron phase.  These three stages are a series of a cycle that all living cells must experience to produce the required energy for the smooth functioning of the mechanism of life.

Why Krebs cycle is important?

Poor digestion, fatigue and lack of proper nutrition are the common complaints among the people of all ages all over the world.  This complaint comes when the body does not get proper nutrition or is unable to digest food even if it's available.  It leads to a chronic problem and makes most of the people suffer. But what makes them suffer? This is the listless metabolism that ultimately leads to slow Krebs cycle function. When Krebs cycle does not function properly, after a period of time it causes the accretion of undigested food remains in the blood vessels and also creates some other health complications such as constipation, fatigue and smoggy brain.  In the long run, it can create some other health complication that is severe and sometimes life-threatening. So to avoid this situation people usually prefer to take the Krebs cycle supplement.  This supplement resolves all these issues and also makes you feel energetic.

Why your body is reliant on Krebs cycles?

Krebs cycles are important since it helps to generate energy from the food, particularly from the carbohydrate. And you can get carbohydrate from grains, cereals, fats and also from vegetable and animal sources. You can also get carbohydrates from the proteins.

By definition, carbohydrates are the combination of three important things, carbon, hydrogen and oxygen and these things can be changed to glucose inside your body. Initially your body uses the carbohydrate as the foundation of glucose and then through a series of processing, the body gets the required amount of carbohydrates from the diet. And here Krebs cycle plays an important role to generate energy from the carbohydrate.

The Krebs cycle is considered important for producing energy, it does not help you to run fast and to be active only, and it also enables your metabolic process to work efficiently.

References:

//www.wisegeek.org/what-is-the-krebs-cycle.htm

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Date: August 15, 2015 01:52 AM
Author: Darrell Miller
Subject: Wheatgrass - A Superfood To Improve Your Energy Levels

The most nutritious of all cereal grasses is wheatgrass.  It is richest in nutrients when it is grown in clean soil and just before the development of its stem. The most interesting factor is that it does not contain gluten. This article aims to list some of the health benefits of wheatgrass and how it can boost energy levels.)

Wheatgrass contains over 90 minerals including Mg, Ca, Na, etc. It has a rich concentration of alkaline minerals.  It contains a number of enzymes such as Lipase (splits fat), Amylase (helps in digestion), Protease (helps to digest protein), and Transhydrogenase (strengthens the heart muscle,etc. , among others).

Wheatgrass contains high doses of vitamin C, almost twice the amount of Vitamin A as in carrots and a full complement of B vitamins.  A teaspoon of wheatgrass powder is nutritionally equivalent to 50 g of spinach salad and supplies an equivalent amount of energy.  Wheatgrass contains 19 amino acids.

Benefits of Taking Wheatgrass

Containing a high number of enzymes vitamins and minerals, it boosts vitality and energy levels. It enhances detoxification and aids in maintaining the correct acid-alkaline base in the body. The high vitamin content helps to increase endurance and stamina levels in the body. Chlorophyll contained in the wheatgrass works to increase production of hemoglobin in the body. With increased blood circulation, the body’s metabolism is improved with increased energy levels. Chlorophyll also serves to alkalize the blood. This slows down aging, increases energy levels, and slow down/prevent degenerative diseases such as arthritis and gout.

The B vitamins and iron in wheatgrass reduce tiredness and fatigue and give way for a more energy in their place. The quick and easy absorption of wheatgrass also contributes to effective assimilation of the nutrients that it contains in the body.

Wrapping up, wheatgrass is one of nature’s most nourishing superfoods that you can lay your hands on.

References

https://www.nutrifiz.co.uk/10-benefits-wheatgrass-drinks-revealed/
//www.bestorganicwheatgrass.com/faq/
//thechalkboardmag.com/50-reasons-to-drink-wheatgrass-everyday
//superfoodking.hubpages.com/hub/How-Wheatgrass-can-improve-your-energy-levels
//liveenergized.com/alkaline-diet-resources/wheatgrass-health-benefits/Read More

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Date: July 21, 2015 05:23 AM
Author: Darrell Miller
Subject: The Dangers of Vegetable Oil

More often than not, when we see the words vegetable oil, we assume that it is good for us since vegetables are essentially beneficial for the body. The truth of the matter is that this kind of oil is mostly derived from seeds such as sunflower, soybean and corn, not from any kind of vegetable at all. Aside from this, their extraction requires a process that uses up a lot of energy and is not good for the environment.

Trans Fats

Unsaturated fats, otherwise known as trans fats, are fats that are usually solid at room temperature but processed in such a way that they are not when they come in the form of oils derived from seeds. These contribute to diabetes, heart disease, cancer and obesity. The sad part is that although there are so many calls to action regarding minimizing the presence of trans fats in food; there is very little that has been done regarding their presence in vegetable oils. How trans fats were developed or discovered will show how scary it actually is. It was discovered while looking for an alternative to tallow which is an ingredient for candle wax. It was cheap and convenient to harness and use. The reason why it is widely used is because of its extended shelf life. It can also be reused several dozen times for frying without changing flavor or adding a rancid taste to the food fried in it.

Mutated Fats

The process of extracting the oils from their sources requires a lot of heating and, for some, even exposure to acids and metals which contribute to the "mutation" that these oils undergo. hydrogenated vegetable oil confuses our bodies into thinking that they are good for us. This is mainly due to the processes that changes their form. HVO alters the structure of our cells, making them weak and lowering the good cholesterol as well as raising the bad. Our bodies welcome these fats and do not treat them as a danger although their presence does, in fact, increase the risk of heart disease, diabetes and other diseases.

Imbalances

Vegetable oils can also cause imbalances in the composition of our fatty acids. Omega 3 and omega 6 fatty acids are not produced by our bodies. Therefore, we need to supplement these from our diets and daily consumption in pretty much the same amounts to balance their presence in the body. Polyunsaturated fats from HVO that causes the mutation in our cell membranes can lead to oxidative chain reactions which are harmful to our cells. In essence, our cells are made weak and the chances of alterations to our DNA are increased. Omega 6 is abundant in HVO because it helps to slow the deterioration of the vegetable oil. It can cause an imbalance to the cell membrane causing inflammation in various parts of the body. One component of Omega 6 that is highly dangerous is linoleic acid. It has been linked to obesity, high levels of bad cholesterol and even damage to the brain's hypothalamus.

These are just a few of the dangers that come with using so called vegetable oils. These dangers are kept under wraps because of the massive income that the food industry will lose if it changes the oils used for cooking and preparing food.

Read More

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Date: August 08, 2014 10:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Low Selenium Affect Thyroid Functions?

What is thyroid glands

Human thyroid glands are small glands with a very important function. The major function of thyroid glands is to regulate body metabolism.

There are two main hormones produced by thyroid glands; thyroxin (T4) and triiodothyronine (T3). The secretion of these 2 hormones is based on the feedback mechanism of hypothalamus and pituitary glands. These hormones influence every body cells- they control the rate at which your body accumulates and uses fat, help to regulate body temperature and also heart rate. In addition, thyroid glands produce calcitonin, a very important hormone that regulates the amount of calcium in the body. There are the major types of thyroid diseases, Thyroid cancer, Hyperthyroidism, Hypothyroidism and Benign disease. But what is the role of selenium in thyroid functions?

Selenium deficiency

Selenium deficiency is not common in healthy adults, but it is common in people with digestive disorders causing low absorption, or those with severe inflammation arising from chronic infection. Research shows that low selenium does not cause illness by itself, but due to its role in immune functions, it makes a body susceptible to biochemical, nutritional and infectious diseases.

But this does not mean that selenium has no direct influence on thyroid functions. Adequate selenium supports the production of thyroid hormones, protects thyroid glands from the adverse effects of excess iodine in the body, and will also improve body metabolism.

Importance of selenium

Selenium is very important and it is always healthy to ensure your normal selenium level. For example, selenium supplements are used to treat autoimmune thyroid condition. Studies have found that selenium supplementation lowers thyroid inflammation. These findings are backed by the fact that selenium increases thioredoxin reductase and glutathione peroxidase activity, and also lowers the toxic concentration of lipid hydro peroxides and hydrogen peroxides which results from the production of thyroid hormones.

Selenium prevents thyroid tissue damage. Selenium is very important because it lowers the level of thyroid peroxides in the blood. In addition, selenium is vital for conversion of T4 to T3. T3 is the active form of thyroid hormones. Low T3 causes hypothyroidism.

How to obtain selenium?

If you think your body is deficient of selenium, it is good to seek medical care immediately. Thyroid glands are very important for the body functions. Selenium supplement is a good solution to thyroid function. But long term use of selenium supplement would cause other complications such as white blotchy nails, hair loss, gastrointestinal upsets, fatigue, irritability, garlic breath odor, and mild nerve damage. In addition, very high selenium in the body may cause hyperthyroidism. In addition, clinical test for use of selenium supplements has found that it predisposes users to the risk of prostate cancer. Though this has not yet been proven. This makes selenium rich foods the best way to increase the level of selenium in the body. Some of the food rich in selenium includes; crimini mushrooms, shrimp, tuna, cod, scallops, chicken, halibut, salmon, shiitake mushrooms, brazil nuts, lamb eggs, and turkey. Brazil nut is particularly very rich in selenium, taking one or two in a day will significantly improve the selenium level and also boost your immune system.

Is selenium important for thyroid function?

Yes, selenium level is very important and low selenium.

References

1. //chriskresser.com/selenium-the-missing-link-for-treating-hypothyroidism
2. //www.wellnessresources.com/health/articles/seleniums_vital_role_in_thyroid_hormone_function/

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Date: June 02, 2014 08:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can L-Leucine Help Glucose Metabolism And Insulin Function?

What is a leucine

Leucine is one of 3 amino acids that increases muscle mass and will also help you to recover after exercise. Leucine supplies the body with energy and regulate blood sugar. Being an essential amino acids, it cannot be synthesized by the body and thus you need to get it from food or supplements. But Can L-Leucine help glucose metabolism and insulin function?

What does leucine do

L-leucine has direct bearing on the amount of insulin produced. L-leucine will stimulate the amount of insulin produced by the pancreas. One of the ways in which it influences the amount of insulin produced is by enhancing glutaminolysis by allosterically activating GDH (glutamate dehydrogenase).

Benefits of leucine

Increased insulin levels have a major implications on glucose metabolism. Increased insulin level will directly result into faster glucose absorption into the blood stream. Increased glucose metabolism prevents the body from using lean muscles to supply energy during workouts. Unlike isoleucine and valine, L-leucine are converted to glucose slowly and thus you can have sustained energy for long.

It is also very effective in muscle building. By stimulating insulin release and glucose metabolism, it enables key nutrients such as amino acids, Creatine and glucose to enter muscle cells. Since insulin will stimulate rapid muscle synthesis while inhibiting protein breakdown, L-leucine will build lean muscle mass with a short period.

L-leucine is alternative to steroids, it is safer and its effects are lasting. During workouts, it supports oxidative metabolism in muscles and decrease protein degradation.

If you are looking for the best way you can build muscle mass and strength without adverse effects, L-leucine is premier supplement. Apart from building muscle, l-leucine will also improve brain functions. You can take more workouts. L-leusine supplement has been used by many body builders and has been proved beyond doubt to be effective supplement. If you have been wondering if l-leucine help glucose metabolism and insulin function, no doubt it is can.

You can also red more by visiting

//www.livestrong.com/article/261185-what-are-the-functions-of-leucine/

//www.ncbi.nlm.nih.gov/pmc/articles/PMC2969169/

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Date: May 07, 2014 11:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes?

Glutamine

Glutamine is considered to be the most abundant natural amino acids which is a building block of proteins in the body. Although the body can already make enough glutamine on its own, extreme stress is the type you could experience after heavy exercise or from injuries can't naturally aid help those pains on its own. The body may need a bit more glutamine in order to truly eliminate those kinds of ailments. Most glutamine is naturally stored in the muscles and lungs.

Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes?

Glutamine is also very important when it comes to removing excess ammonia which is a common waste that grows in the body. It has also been shown to help your immune system to function more normally to create proper brain function and bowel movements. Glutamine is naturally utilized at high rates by the isolated incubated lymphocytes that produces glutamate, lactate, and aspartate. The pathways for glutamine metabolism can include reactions catalysed by aspartate aminotransferase, glutaminase, succinate dehydrogenase, oxoglutarate dehydrogenase, fumarase, and phosphoenolpyruvate carboxykinase. Having high levels of glutamine in the body has been claimed to help improve the body's lymphocites and intestinal cell enterocytes in the body.

This is why numerous product contains a high levels of glutamine to help with imbalanced areas in the body. Purchasing the purest of glutamine products is the best way to get the most benefits out of it. Glutamine can also help increase the metabolism promoting a much easier time maintaining your weight. Increasing your glutamine can definitely do wonders for your daily life, as it will improve numerous aspects in your body.

In conclusion, be sure to boost your glutamine while your young so that when you get older, you body has a great storage of it when it may need the most.

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Date: May 07, 2014 09:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Glutamine Improve Nitrogen Balance in the Body?

Can Glutamine Improve Nitrogen Balance in the Body?

Glutamine also abbreviated as Q is one of the 20 amino acids the genetic code encodes. Glutamine is not an essential amino acid and this means the body can produce it. It is the most abundant of all amino acids with a concentration of 500 to 900 molecules per liter.

Glutamine structure

It has an amide side chain that is formed by replacement of an hydroxy group of glutamic acid. It is coded by COG and CAA.

Glutmine and nitrogen balance

Glutamine does actually improve nitrogen balance in the body. The regulation mechanism occurs by feedback inhibition mechanism. The deamination of glutamate by glutamate dehydrogenase leads tp production of ammonia (NH3) and an alpha ketoglutarate. High concentrations of ammonia can be dangerous to the body, they are neurotoxic and cause disruption of the Urea Cycle and affect the liver. High concentrations of ketoglutarate helps activate glutamine synthetase which acts a a catalyst in the synthesis of glutamate.

This process is controlled by 9 feedback inhibitors. Of the 9 inhibitors, six are products found in glutamate pathway cycle. This helps in regulation of nitrogen at cellular level which is very sensitive. It helps control ammonia levels which can be dangerous at high levels.

Improving anabolic state of the body

Glutamine helps the body muscles recover after intense training. This occurs through energy repletion in the muscles. Boosting of the immune system has also being discovered to be associated by glutamine. It also buffers against the build up of lactic acid in muscles leading to muscle growth.

Glutamine increases the size of the cells and promotes the integrity of the intestines leading to increased absorption by the cells. It also releases a growth hormone that helps in muscle growth.

Conclusion

Essentials of glutamine have been found to be many. Nowadays there are commercially produced glutamine which are taken as strong anti-catabolic supplement.

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Date: March 06, 2014 03:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Cocoa Butter Good For The Skin? Why?

Cocoa butter

Doubtlessly, there are few preferred healthy skin items over cocoa butter and some few that likewise makes you feel great deductively notwithstanding feeling extraordinary because of the way your skin looks so great, but Cocoa butter is good solid skin reinforcement, and for additional data on characteristic healthy skin items with a great experimental foundation. Therefore it is good for the skin.

Reasons to why cocoa butter is good for your skin:

Powdered cocoa butter contains a lot of diverse antioxidants which behave synergistically presenting a massive bothersome resistant to the cost-free radicals which eliminate your skin layer cells along with lead to quick getting older. Therefore, therefore, is it doesn't suitable natural skin care solution.

Let's have a look at which record again. Precisely why your 'ideal' natural skin care solution? In order to solution which question, we need to have a look at precisely what antioxidants tend to be, along with precisely what hot cocoa butter can perform them, along with after that the reason why it is advisable than additional natural skin care merchandise on the market.

Totally free radicals tend to be small substances kinds in the body's fat burning capacity while vitality is generated coming from blood sugar in the mitochondria of each and every cell phone within your body. Fortunately they are shaped simply by experience of toxins including pesticides, along with particularly the several poisonous pieces of cigarette light up. Cigars along with water lines tend to be believe it or not harmful than tobacco, along with filtration system guidelines make not any difference towards the production connected with cost-free radicals.

What exactly that they do is always to eliminate cells, when they're pores and skin cells you continue to grow older. Your skin layer wrinkles along with dries up, and you begin to take on the style connected with an individual many years over the age of you're. These people try this by way of a procedure often known as oxidation, along with antioxidants can certainly keep the idea. These people reduce the effects of your cost-free radicals, and forestall your skin layer cells coming from getting ruined.

Contents of cocoa

Powdered cocoa butter contains several different antioxidants that can eliminate away from numerous diverse cost-free radicals along with superoxides, as well as hydrogen peroxide. Vitamin e is really a powerful antioxidant -- your strongest of all the so-called antioxidant vitamin supplements in fact, and will quickly eliminate away from hydrogen peroxide along with any oxidizing agent. Others tend to be vitamin supplements A new along with G, however they can not strategy the potency of vitamin E.

Furthermore, it contains phytochemicals (posh title pertaining to place chemicals) including flavanoids which might be also powerful antioxidants. Polyphenols are very effective in neutralizing cost-free radicals, and the hot chocolate mass polyphenols tend to be in particular successful. In fact, hot chocolate butter boasts a greater antioxidant awareness and then possibly blueberries as well as other so-called superfoods.

In order that hot cocoa butter to work, it will email numerous of the pores and skin cells as is possible, that involves do away with the idea properly directly into your skin layer. The epidermis is incredibly absorbent all of which will eliminate cost-free radicals in the reduced absolute depths of the pores and skin as soon as they're created, along with ahead of they are able to do injury.

It is clinically demonstrated which hot chocolate butter will certainly keep pores and skin degradation a result of the harmful consequences from the UV light in the rays of the sun -- UV rays builds cost-free radicals which are very effective in doing damage to pores and skin. Merely go through the influence connected with sunburn! However, there is additional in order to hot chocolate butter than which.

It contains a substantial percentage connected with vitamins as well as lime scale, potassium, magnesium, zinc, manganese, copper along with metal, all of which come in a highly bioavailable style which make them far better which business vitamins. Not just that, though. Furthermore, it contains tryptophan, involved in the development connected with serotonin, your 'feel good' neurotransmitter, and also dopamine along with phenylethylamine, many beneficial materials. It is a mental faculties food as well as food to your pores and skin.

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Date: February 09, 2014 08:50 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Xylitol?

What is Xylitol?

Xylitol is a 5-carbon Sugar alcoholic recognized even more particularly like a polyalcohol (polyol) and it has already been getting used because the 60's. You can find this within nourishments with regard to unique nutritional reasons as well as a number of without having Sugar goodies, candy, mints as well as biting down hard gums.

Never such as additional designed sweeteners, for instance, sorbitol, mannitol xylitol assists an all natural flavor and it has absolutely no after-taste. This particular organic sweetener additionally statements in order to help fat loss since it offers forty % less calories from fat compared to Sugar. Due to the reduced glycemic report worth associated with simply 7, this particular Sugar alcoholic beverages has developed into well-liked choice along with diabetes or even people with hypoglycaemia. It's minimum effect on blood sugar levels as well as doesn't assist insulin in order to metabolize. Some of the greatest recognized wellsprings of the Sugar alternative tend to be fruits, mushrooms, as well as lettuce.

In spite of, actually these types of sustenances most abundant in raised levels include only a fragile quantity of the actual Sugar. For example, 1 cup associated with raspberries consists of simply not precisely 1 gram from it. Appropriately, this particular Sugar alternative is actually in a commercial sense ready with the hydrogenation associated with wooden Sugar (zylose) deduced in the xylan hemicellulose polymer bonded present in hardwoods, hammer toe husks, birch trees and shrubs, oats, nutshells, and so forth. The entire chemical substance process is actually vitality severe as well as big size, consequently causeing this to be Sugar alcoholic beverages 10 occasions more expensive compared to desk Sugar, sucrose.

Additionally, I have to stipulate which around it's producer statements which it's 100% organic Sugar, the way in which this particular sweetener may be handled as well as changed in order to draw out the actual Sugar deposits certainly merely does not seem because wholesome or even an amazing identical to something which normally occurs within meals developed in the floor, is not which correct? It is just difficult to think about this a proper Sugar whenever it's already been therefore extremely dealt with.

Is Xylitol Safe?

Indeed, the actual FDA offers mentioned which Xylitol is actually secure with regard to human being usage within never-ending amounts. The primary threat may be the concern associated with Xylitol as well as young puppies. Don't allow your dog consume Xylitol as it might result in a unexpected as well as possibly deadly decrease within dog sugar!

What exactly are Xylitol's Many benefits?

1. It is normally fairly sweet without any unusual aftertaste

2. Appears & preferences such as Sugar

3. 40% less calories from fat & 75% much less carbohydrates compared to Sugar

Xylitol's Dental & Dental care Advantages

Xylitol represses the power associated with germs to stick to tissue within the mouth area as well as can't be digested through germs, therefore it significantly shells from the procedure which produces dangerous, enamel-eating acids.

1. No cario-genic (doesn't trigger cavities)

2. Reduces cavities through 80%

3. Substantial long term reduction in cavities (88-93%)

4. Reduces dental care plaque development through producing plaque much less adhesive

An additional well-known wellness declare of the Sugar is actually it's capability to homicide germs and steer clear of teeth rot as well as dental illness. It's also believed to assist reduce plaque as well as impede current cavities through decreasing. Like the majority of Sugar alcohols, it may change the calm laxative effect from higher dimensions. Based on research brought within 1977, spending 1. four oz . from the Sugar alcoholic beverages for each day time may cause diarrhoea in several topics. It's producer announced which within doses associated with bigger than 15 gr, that is around 3 teaspoons, the actual sweetener isn't secure for everyone to make use of. Diagnostic tests exposed which 1. 65 gr from it might lead to passing away inside a 100gram rat. An average little bit of xylitol-gum consists of 0. 7 -- 1 gram associated with xylitol, and therefore about 50 % the quantity of the actual sweetener is needed to perform the rat.

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Date: January 24, 2014 10:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Facts about whey protein.

Whey Protein

Whey protein refers to one of the two significant parts of milk, whey is the fluid parcel of the milk that divides from the curds (the other real part), throughout the process of cheese processing. Whey proteins are made up of fats, sugars, vitamins, and minerals. Because of its tough amino acid acerbic profile and simplicity of withholding, it is ostensibly the most prominent games nourishment supplement.

Whey protein exists in three principle structures:

Isolate, concentrate, and hydrolysate. This article will concentrate on how different is concentrate from isolate. Both structures have whey protein, but whey isolate, which is created out of whey concentrate, goes through further processing which yields an end product with more protein per unit than whey concentrate.

Then again, the whey protein isolation procedure is significantly more exhaustive. It basically differentiates the protein, just about in its sum from the crude whey, bringing about 90-94% pure protein. So in a 50-gram serving of whey protein isolate, move toward getting 45-47 grams of unadulterated protein with the remaining 3-5 grams being maybe 1 gram of crabs and some calcium, potassium and sodium.

You may tend to think that whey protein is spring water because as it is separated, pure and also healthy, yet contains the greater part of the minerals and so forth of regular water. While whey protein disengage is like refined water, as it is water in its purest structure with essentially all different particles evacuated additionally a hydrogen and oxygen atom

The essential distinction between isolate and concentrate

Isolate is the most unmodified type of protein. Whey isolate typically have between 90-94% proteins while whey concentrate has a protein proportion of around 70-85%.

In the event that you are you are not fit for lactose and you have issues with gas then the whey protein isolate is the better decision. Whey protein concentrate is also an astounding source of protein and concentrate has higher BV qualities contrasted with lean red meats, chicken, fish and entire eggs. Isolate whey is more expensive than other forms as Isolate has been filtered more than concentrate some of the important immune-boosting protein components have been removed and some say the protein is degraded more making it less useful to the body.

The following sites have more on whey proteins that every consumer should know.

References:

1. www.allmaxnutrition.com
2. www.2buildmusclefast.com
3. www.bodybuilding.com

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Date: January 16, 2014 05:32 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Beta Alanine And How Does It Improve My Athletic Performance?

Beta alanine

Beta-alanine is classified under non-essential amino acid; which imply that the body is able to produce.

Amino Acid

Amino acids are the building components of proteins. Beta-alanine is a precursor to the compound carnosine; which, functions by regulating the acidic environment resulting from active muscles. In a case where the cellular environment inside the muscle becomes too acidic, then the muscle ceases to function. To prevent this carnosine slows down or attenuates the development of an acidic environment allowing an athlete to perform better or exercise with more work load.

What is Carnosine

Carnosine is very effective at controlling the hydrogen ions that cause then negative effects of lactic acid. Carnosine is understood to be one of the main muscle buffering substances contained in skeletal muscle. Therefore when carnosine prevents the arising of an acidic environment which characterizes a high-intensity exercise, the athlete is able to exercise at high intensities for a longer period.

When carnosine is ingested directly through the mouth it is rapidly converted into beta-alanine and histidine by the enzyme carnosinase as soon as it enters the blood stream. It is thus ineffective when carnosine is ingested directly. However,separate ingestion of beta-alanine and histidine results in these two compounds re-conversion to carnosine after absorption into the skeletal muscle.

Beta-alanine has great benefit in improving athletic performance and exercise intensity, and the building of lean muscle mass.

Research indicates that beta-alanine is the amino acid that highly affects intramuscular carnosine amount as it is the rate-regulating substrate in this chemical reaction (Dunnett and Harris 1999).

Recommended Use for Beta Alanine

It is highly recommended that beta-alanine be taken in daily dosages in order to be highly effective, with dosage amounts varying from different expert opinions as well as dependant on the athlete preference.

Studies have indicated that 28 days dosage of 4 to 6 g/day of beta-alanine supplementation resulted in an approximately 60% improvement of intramuscular rates (Harris et al. 2005; Zoeller et al. 2007)

References:

1. //www.humankinetics.com
2. //www.nutritionexpress.com

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Date: January 10, 2014 05:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What IS NADH And Why Would I Want To Take It Daily?

What IS NADH And Why Would I Want To Take It Daily?

NADH is a chemical that is naturally created in the body and plays the role of generating energy, NADH stands for Nicotinamide Adenine Dinucleotide with hydrogen.

But there are some individuals who have a lesser production of this chemical and because of that medicine providers have created NADH supplements.

What are the uses of NADH?

NADH supplements are effective for providing focus, improved concentration, and mental clarity as well as upgraded memory skills.

For this reason some people are taking it daily, people who have Alzheimer’s, for example are given this drug.

Not only that people also use NADH to improve their energy production, athletes use it to increase their endurance, while others are using this supplement to cure their chronic fatigue.

Other uses of NADH

Will include treatment for blood pressure, it can also reduce cholesterol.

Some clinical studies have revealed that is also effective for curing signs of depression as well as Parkinson disease. It is also recommended for people suffering from liver and hormone problems, it works by strengthening the immune system.

Individuals who have AIDS and are currently taking a drug called zidovudine or AZT also use NADH to combat the side effects of the drug.

While it is used for complex problems, other people just simply use it to relieve symptoms of jet lag.

Why do some people prefer to use NADH supplements?

NADH is said to be safer than other supplements in the market, it is also safer to use compared with carbonated drinks and energy drinks. It provides extra energy for people to use it, it helps people become alert.

This is perfect for individuals who want to maintain increase their day-to-day energy level. Single mothers have reported satisfaction over this drug, with only 10 mg of this supplement they are already given extra energy to take care of their kids.

NADH also works as a way for people to regain youth and vitality, the extra energy produced in the body inspires people to do more.

References:

1. //enadh.com/blog/all-day-energy-with-every-day-use-of-nadh/
2. //www.webmd.com/vitamins-supplements/ingredientmono-1016-NADH.aspx?activeIngredientId=1016&activeIngredientName=NADH

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Date: December 29, 2012 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Super Oxide Dismutase (SOD)?

Super Oxide Dismutase is an important enzyme that plays an important role in protecting the cells from free radical damage. Enzymes are compounds that work by speeding up certain chemical processes in the body. Super oxide dismutase speed up the process of transforming superoxide into oxygen and hydrogen peroxide, making SOD an important component in the processes of providing oxygen to the cells. Without oxygen, cells eventually stop functioning and die.

Benefits of Super Oxide Dismutase (S.O.D)

This enzyme is present in various living organisms even in some bacteria species that do not utilize oxygen. Because of its function in providing oxygen to the cells, super oxide dismutase is important in keeping cells healthy and ensuring the function of all organs in the body. Without it, cells rapidly age and die, and the body becomes exposed to various kinds of diseases and infections. This becomes more pronounced in individuals who are constantly exposed to pollution and other sources of free radicals. Fortunately, the enzyme is available as a supplement for those who want to ensure that they have the right amounts of super oxide dismutase in their systems. It is important to seek professional consultation before taking the enzyme, but it is often allowed for most people in varying degrees of health.

Top Uses of Super Oxide Dismutase

Super oxide dismutase is often used to treat various types of organ malfunctions like bladder infections as well as to prevent lung infections in newborns suffering from compromised respiratory systems. This is very important in premature newborns since giving oxygen to a newborn can damage his lungs. The enzyme is also used by bodybuilders and those who want to stay fit and healthy since it enhances oxygen delivery and promotes longer endurance when working out. The antioxidant property of SOD also helps in keeping cells healthy and supports cell tissue repair after strenuous workouts.

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Date: March 08, 2012 06:50 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Health benefits of Omega 3-6-9 fatty acids

What AreThe Benefits Of Omega-3-6-9?

In order to maintain the normal function of the body, it is important that our diet consists of the right amounts of various fatty acids. These are organic compounds made up of carbon chains of various lengths, with one end having an acid group and a hydrogen on the end all attached to the carbons in the chain. Omega-3-6-9 fatty acids are vital ingredients that play important roles in the body.

Omega-3 fatty acids are referred to as essential fatty acids because they cannot be synthesized in the body and must be obtained from foods such as nuts, fish or plant oils such as canola and sunflower. These essential fatty acids exists in three types, alpha-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid each with an important role to play in the body.

The alpha-linolenic acid help to reduce the high risks of stroke and heart disease by lowering cholesterol level and slowing down the production of harmful triglyceride in the liver while at the same time raising the level of high-density lipoproteins, HDL or good cholesterol in the body. They also prevent the accumulation of harmful fat in the arteries and promote the elastic nature of the blood vessels.

Both eicosapentaenoic and docosahexaenoic acids promote the development of the eye and brain, reduces risks of cardiovascular diseases, and may aid in preventing Alzheimer's disease. A study based on eicosapentaenoic and docosahexaenoic acids conducted on a ten year period on individuals who had high risk of death from heart disease revealed a 40% decrease in cardiovascular disease and a dramatic reduction in mortality rate.

Omega-6 fatty acids are also essential fatty acids that cannot be produced by the body and must be obtained from chicken, eggs, dairy products and various plant oils such as corn oil, rice bran oil among others. In association with its derivative, the alpha-linoleic acid they aid in production of prostaglandin which plays a vital role in promoting the normal function of the brain, nerve and immune system.

They also help in reducing incidences of coronary artery disease by lowering the level of cholesterol in the arteries. By consuming the right amounts of essential fatty acids, a balance is achieved and both essential oils work synergistically to promote the overall health of the body by preventing various inflammatory disorders.

Omega-9 fatty acids are a class of unsaturated fats commonly found in animals fats and vegetables and are also called monosaturated fats or oleic acids. They are usually produced by the body unlike the essential fatty acids but can also be obtained from various plant oils such as sunflower, olive, canola as well as other mono-saturated fats. Research studies have revealed that the mono-saturated fatty acids may help in reducing the risk of stroke and cardiovascular diseases.

This is because, they have been found to play an important role in increasing the level of high-density lipoproteins or good cholesterol and decreasing the level of high-density lipoproteins or bad cholesterol in the body. They also prevent the unwanted plaque deposits in the arteries and this reduces the risk of developing coronary artery disease. Despite the fact that Omega-3-6-9 individually play different roles in the body, it is clear that striking a balance of the essential fatty acids plus non-essential fatty acids is important for promoting the overall health of the body.

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Date: February 07, 2012 07:50 AM
Author: Darrell Miller (support@vitanet.net)
Subject: History And Uses Of Xylitol

Xylitol is the 5-carbon sugar which is found within the birch tree sap and it's naturally found in the fibers of various vegetables and fruits. This is a sugar-alcohol sweetener commonly used as the sugar substitute.

History of xylitol

Although discovered in the 19th century during the Second World War, Xylitol has been recognized ever since the tardy 1800s. The researchers from Germany and France were the first individuals to try to produce this product approximately 100 years ago, but ended up creating syrup-like consistency mixture. This product became commercially available in the 1960s and the commercial process is still the same as it was during the 1960s.

Before 1943, the scientists' categorized this sugar with various sugary carbohydrates (polyols) and it lingered so till the beginning of the war-associated deficiency of sugar which initiated the call for an alternate sugar. This initiated further research in to the xylitols insulin-independent properties, this resulted in discovery of its other biological benefits. In 1962 this chemical was introduced in the infusion therapy demonstrating that it can be introduced to ill individuals.

The commercial production process involves extraction of Polysaccharides rich in Xylose from various agricultural by-products and hardwoods. These are hydrolyzed with various intense acidic treatments and then it is purified before hydrogenation is done. This process needs a lot of harsh chemicals and is quite expensive and inefficient.

It was until 1970 that the odontological benefit of xylitol was ascertained in Finland, Turku. The initial study of the effects of this sugar on the dental plaque began during the same year. This resulted in large scale production of xylitol, in 1974 by the Finnish sugar company. Sugar-free dental product was first launched in Finland which was a xylitol chewing-gum.

How xylitol works

This sugar can prevent cavity in various ways by actually blocking the tooth decaying process. The bacteria causing decay cannot ferment this sugar into acids as it does with other sugars including dextrose, fructose, glucose and sucrose. This results in production of less acidic by-product thus interfering with the dental plaque environment which favors decaying. This results in prevention of tooth demineralization.

The high pH condition caused by xylitol sugar is not favorable for the cariogenic bacteria which are responsible for decaying. This results in fewer bacteria in the plaques and long-term exposure has an effect on which type of bacteria will prevail within the plaque. This also inhibits the growth of specific xylitol-sensitive bacteria strain. Since they cannot breakdown this sugar, they end up not reproducing and growing in population. The lack of fermentable sugars results in creation of anti-cavity effect.

The starvation effect created by this sugar prevents accumulation of cariogenic bacteria in the plaques. Long term xylitol exposure results in change of predominant cariogenic bacteria to xylitol-resistant strains from xylitol-sensitive. This xylitol-sensitive strain of bacteria cannot colonize the plaque since they have less adhering capabilities.

The less acidic condition in the dental plaque interface created by this sugar can initiate demineralization. Demineralization occurs when the plaque interface is at a pH of 5.5 or below since fewer bacteria live in the plaques. Studies have showed that demineralized tooth samples immersed in a solution containing 20% xylitol experienced a great remineralization degree. This is noted in the deep and middle tooth layers.

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Date: October 13, 2011 03:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Fast Does Acidophilus Capsules Work?

Acidophilus And Colon Health

The body contains a normal flora of good microorganisms which is helpful not only in protecting the body from harmful microorganisms but also in the production of several body fluids and enzymes required for its many biological processes. One of the areas of the body which has an abundant number of good bacteria is the digestive tract. As many health experts claim, “Good digestion largely depends on a healthy digestive tract”.

However, these floras of good bacteria in the stomach and intestine can be easily depleted under certain circumstances which include excessive stress and antibiotic therapy. In antibiotic therapy, it is not only the bad bacteria that are destroyed but also the good ones. Antibiotics will greatly lower the population of good bacteria in the stomach and intestine. Under stressful conditions, the good bacteria may be gradually destroyed by the bad bacteria inside the digestive system and since the body is under stress, it cannot produce enough number of good bacteria which can outnumber the bad bacteria. Good thing, there are supplements which can increase the number of good bacteria in the gastrointestinal tract. These are called probiotics. One of the most common probiotics is Lactobacillus acidophilus. This is effective in adding more good microorganisms in the digestive tract thus helping in the maintenance of a healthy and reliable intestinal flora.

Lactobacillus acidophilus

Lactobacillus acidophilus consists of billions of live good bacteria which can greatly help in promoting healthy digestive system and good digestion. Most studies revealed that the improvement of digestion would be apparent about a week or two. Probiotics supplements can be used everyday and can be taken together with prebiotic supplements. Prebiotics, on the other hand, are not live cultures of good bacteria but are supplements to help the existing good bacteria inside the digestive tract to produce more good bacteria. The two can effectively work hand in hand to improve digestion.

Lactobacillus acidophilus can help defend the body against harmful microorganisms. When it is used by the body, its by–product called hydrogen peroxide can make an unfriendly environment for bad bacteria. This toxic environment helps kill and eliminate bad bacteria thus maintaining the health of the digestive system. Lactobacillus acidophilus can also produce certain enzymes which can be helpful in the breakdown and absorption of food nutrients which are essential to the human body. The best widely – known source of Lactobacillus acidophilus is yogurt. It is easily discernible because of its sour taste due to its lactic acid content produced by the billions of Lactobacillus acidophilus. Other food products which are considered as good source of Lactobacillus acidophilus are sauerkraut, kefir, aged cheese and many other fermented products. Lactobacillus acidophilus is also available in the form of pill supplements. One pill approximately has an amount of three billion live cultures of Lactobacillus acidophilus depending on the brand you purchase for internal use.

If you have ever been on antibiotics, you should be taking acidophilus daily!

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Date: October 04, 2011 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Supplements Are Useful In Combating Blood Clots?

Vitamins And Your Health

As we know for a fact, one of the properties of blood is its ability to coagulate in order to stop bleeding. This coagulated blood is commonly known as a clot. Blood clot is important to the body to prevent excessive bleeding and serves as a vital part in the process of inflammation and wound healing. However, if a clot occurs abnormally it can cause significant danger to the body. A blood clot can cause obstruction in the circulation and may result to life - threatening health conditions such as heart attacks, cerebrovascular accident or strokes and pulmonary embolism. It can also cause poor tissue oxygenation and perfusion which can damage the affected cells and might cause disability or inability to function of certain organs or body part.

There are many traditional modalities in preventing and treating abnormal blood clot formation. One of the most commonly used is the medication called Aspirin in low – dosage. This conventional drug is popularly prescribed by doctors to decrease the clotting property of the blood. However, in emergency cases, a surgical procedure may be deemed important to remove the blood clot which significantly interrupts proper blood circulation.

Aside from medications, there are many supplements that have the capacity to decrease the risk of abnormal blood clotting. These include supplements high in:

1. FISH OILS. Fish oils are rich in omega-3 fatty acid which has the capacity to thin the blood. Therefore, if the blood is not viscous, the pressure inside the blood vessel is lesser as well. A high blood pressure can cause damage to the walls of the blood vessels, thus activating blood clot formation. Also, a non – viscous blood can also better circulate into smaller blood vessels than that of a viscous blood, therefore, enhancing tissue oxygenation. Clinical studies also revealed that omega – 3 fatty acids can effectively decrease Thromboxane A which is one of the clotting factors found among platelets.

2. CHAMOMILE. This herb has an anti – platelet property. It has a mild to moderate effect in regulating clot formation.

3. GINGER. Ginger has many health benefits. One of its promising benefits is its mild anti – platelet property and its ability to dissolve fibrin. This herb is widely used as a supplement to enhance blood circulation all over the body.

4. CATECHIN AND QUERCETIN. These chemical compounds are classified as antioxidants. They can effectively reduce the adhesion property of platelets.

5. CURCUMIN. This chemical comes from the spice called turmeric. This is considered to be an anti – thrombotic, as well as a potent anti – inflammatory agent.

6. DEHYDROEPIANDROSTERONE (DHEA). This substance is primarily an anti – aging agent. However, studies reveal that it can significantly reduce the process of inflammation by preventing the substance that can generate inflammation within the veins, arteries and capillaries called Cytokines. With decreased production of cytokines, it will result to lesser coagulation and clumping of platelets and reduced movement of bad cholesterol or Low Density Lipoprotein (LDL) into the walls of the blood vessels, thus decreasing the chance of clot formation and atherosclerosis.

7. VITAMINS C AND E. These vitamins are important for preventing abnormal collagen – induced platelet activation by inhibiting the production of hydrogen peroxide. Vitamins C and E are also important in many enzymatic actions that regulate blood cholesterol levels.

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Date: August 29, 2011 10:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Vitamins And Minerals Are For Mental Alertness?

There are many vitamins and minerals which can help improve the health and functioning of the nervous system. Vitamins and minerals are significantly involved in many biological processes of the body. It influences the activities of the organs of the body including the brain. In fact, deficiencies on vitamins and minerals may result to psychological or even psychiatric symptoms in certain individuals. People with psychiatric problems are also prescribed with vitamin and mineral supplements which serve as one of its conventional treatment.

The vitamins and minerals which are good for the improvement of brain function and improvement of mental alertness are the following:

1. THIAMINE OR VITAMIN B1. Generally, insufficient amount of this enzyme may result to mild psychiatric symptoms. Studies revealed that people with inadequate amount of this vitamin has the symptoms of fearfulness, anxiety, depression, agitation and behavioral instability. This vitamin is necessary for the activity the body’s enzyme called pyruvate dehydrogenase. This enzyme is required for the conversion of pyruvate to acetyl – coenzyme A. If pyruvate is not catalyzed into acetyl – coenzyme A, the excess pyruvate in the body might be converted into lactate which can cause muscle pains and also psychiatric symptoms such as anxiety. Deficiency of this vitamin must be suspected when the person is alcoholic or malnourished.

2. RIBOFLAVIN OR VITAMIN B2. This vitamin is closely associated with major depression in relation to oxidative stress. Riboflavin is required for the metabolism of protein, fats and carbohydrates. The building blocks of these macronutrients are important for the maintenance of brain health and proper functioning of the nervous system. It can improve the energy levels and functioning of the brain, thus improving an individual’s mental alertness.

3. PYRIDOXINE OR VITAMIN B6. Studies show that low level of vitamin B6 is directly related to depression. Inside the body, pyridoxine is converted into its biochemical active form called pyridoxal phosphate which is important for mental alertness and brain functioning. Pyridoxine acts as a coenzyme involved in the synthesis of brain chemicals such as serotonin, dopamine and gamma aminobutyric acid (GABA). This vitamin is also involved in the metabolism of carbohydrates and amino acids which are essential for boosting energy levels.

4. COBALAMIN OR VITAMIN B12. Deficiency of this vitamin is closely related to decrease mental functioning. Vitamin B12 is a cofactor of the enzyme methionine synthase which is important in the conversion of homocysteine to methionine. This is required for the production of energy in fatty acids and proteins which is important for the methylation reactions of brain chemicals.

5. VITAMIN C. This vitamin is considered to be a cofactor of the neurotransmitter dopamine and is involved in the conversion of dopamine to norepinephrine. These brain chemicals are important for the maintenance of proper mental alertness.

6. FOLATE. Decreased mental alertness and depression is a common symptom of low levels of folate in the body. This mineral is involved in the methylation and synthesis of DNA. It is important for the development of brain function and improvement of mental alertness.

7. MAGNESIUM. This mineral is involved in many reactions of the body. Individuals with decreased mental alertness are found to have low levels of magnesium in their cerebrospinal fluids.

8. ZINC. This is a mineral which is important in the catalyses of many enzyme sin the body. It is found in high amount in the brain which is important for nervous activities.

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Date: May 23, 2011 01:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why is Xylitol So Good for You

Xylitol and Its Health Benefits.

Xylitol is fruit sugar that occurs naturally in fiber-rich plan-based foods, such as berries, oats, and mushrooms. Its sweetness has been compared to table sugar, the disaccharide sucrose to be specific. Unlike simple sugars and most other carbohydrates, it contains much less calories, making it one of the best natural sweeteners. More importantly, it has been associated with numerous health benefits.

The medicinal properties of xylitol were first noted in the second half of the 19th century, when it was introduced as a sugar substitute primarily for individuals afflicted with insulin resistance and diabetes mellitus. It is in fact a hydrogenated form of carbohydrate, which is also referred to as sugar alcohol. That being said, it does not impact insulin levels but rather contributes to healthy blood sugar.

Prevents Dental Carries

One of the earliest documented health benefits of xylitol is its role in preventing the formation of dental carries. Also known as tooth decay, dental carries result from the breakdown of hard tooth structure in the presence of bacteria. It is believed that over 90 per\cent of the global population experience caries at least once in a lifetime, with children being more susceptible.

It should be noted that bacteria taking up residence in the mouth cavity rely on fermentable carbohydrates for nutrition. The products of fermentation are acids that are capable of denaturing the mineral content of teeth, leading to rampant dental carries over time. The use of xylitol has been advocated for over a century since it is not fermentable, unlike glucose, sucrose, and fructose, which are almost always found in the human diet.

Fights off Infections

Xylitol has been observed to display disease-fighting properties. In fact, it has been utilized in the treatment of several bacterial and fungal infections. This sugar alcohol has long been reported to produce metabolites upon exposure to saliva. These metabolites are organic compounds that interfere with the ability of bacteria to adhere to the tissues of the oral and nasal cavities.

More importantly, xylitol appears to enhance the effectiveness of mucus, antibacterial compounds, neutrophil granulocytes, and various enzymes that often get in contact with pathogens first. Regular intake of xylitol has been effective against oral infections of Candida yeast. It has also been cited in the treatment of ear infections, such as acute otitis media. Not surprisingly, it relieves sore throat.

Regulates Blood Sugar

Xylitol is one of the oldest recommended substitutes to sugar. It has a very low glycemic index, which makes that sugar levels in the blood rise gradually and steadily throughout the day. By so doing, it does not cause an insulin spike or impact blood sugar levels. Xylitol is an ideal source of energy for those who are suffering from metabolic syndrome and those who are following a low-carbohydrate diet.

If you haven’t started xylitol, isn’t it time too?

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Date: January 21, 2011 02:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: You Can Combat Adrenal Fatigue!

Have you experienced having difficulty to get up or stay awake in the morning, requiring caffeinated products to keep you going during the day or just being unusually tired for no reason? If your answer is “Yes!” to any or all of these questions, you may be experiencing Adrenal Fatigue.

Physiologically, the adrenal glands, which perch atop the kidneys, produce a manifold of hormones that are vital to life. In instances where there is inadequate production of these hormones, an individual generally undergoes a group of signs and symptoms including fatigue, low blood pressure, lightheadedness, unexplained body aches, sleep disturbances and digestive problems, unusual weight loss and loss of body hair. This group of signs and symptoms is termed as Adrenal Fatigue.

Adrenal Fatigue is a term coined in 1998 by Dr. James Wilson that refers to a cluster of both subjective and objective manifestations which an individual may experience due to insufficient adrenal function. People who are at higher risk of acquiring this condition are those who are experiencing frequent, extreme and persistent psychological, emotional or physical stress. This condition can be diagnosed by blood tests and stimulation tests that can reveal inadequate levels of adrenal hormones. Many tests are highly suggestive but an elevated plasma ACTH level associated with a decreased plasma cortisol level is diagnostic test for adrenal fatigue.

Adrenal Fatigue can be prevented naturally through lifestyle modification. Lifestyle changes such as more laughter in a day, short breaks during extreme psychological or physical stress, regular exercise, adequate sleep and relaxation and regular meals. It is important not to skip meals and food must be chewed well. Another tip for healthy adrenal glands is taking a daily supplement of vitamin C, pantothenic acid, magnesium and vitamin E.

Adrenal Fatigue is not a life-threatening condition. However, it can significantly affect an individual’s optimum functioning on his or her everyday life. This condition is mild, lasting about a few days or weeks, with good prognosis and with full recovery. Though, there are a small number of individuals who will undergo recovery difficult. The diet suitable for individuals having adrenal fatigue includes one that is composed of unrefined carbohydrates such as whole grains, high protein, high fat and high fiber at most meals. In addition, caffeinated products, hydrogenated fats and junk foods must also be minimized. Avoiding carbohydrates from root crops such as potatoes, limiting sugary fruits such as melons and lessening instances of becoming over-tired are also promising in the full recovery from adrenal fatigue.

Like any deficiency, supplements are also available to help combat Adrenal Fatigue. There are many glandular extracts that includes adrenal and other glands of the human body. Hydrocortisone (Cortef), for instance, is sometimes initiated as a hormonal replacement when the hormone cortisol is not or inadequately produced by the adrenal glands. However, this kind of treatment is typically the last resort because hydrocortisone may treat adrenal fatigue but it can make the adrenal glands weaker rather than stronger. Treatment using this hormonal supplement usually takes 6 months to 2 years.

A good diet goes a long way in supporting the adrenal glands. If you are under a lot of stress and cannot change the amount of stress you experience due to work or marriage adding a b-complex can help restore adrenal function and combat stress.

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Date: January 13, 2011 05:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Krebs Cycle - Our Lifes Blood!

The Krebs Cycle, also known as the Citric Acid Cycle, is an important series of biochemical reactions that are intrinsic to cellular respiration and the generation of energy from oxygen and glucose in aerobic organisms. Although humans can generate energy anaerobically, they cannot do so for long periods and oxygen is essential for life because it fuels the Krebs Cycle. Without this cycle, there would be no available energy to maintain our vital processes.

What is The Krebs Cycle

We shall first discuss exactly what the Krebs Cycle is and then its importance in the body. The process takes place within the mitochondria of the body cells.

A. The cycle begins with the ten-step pathway of glycolysis, during which glucose is converted to two molecules of pyruvate: no oxygen is required for this step. Basically:

Glucose + 2NAD+ + 2P + 2ADP = 2Pyruvate + 2NADH + 2H+ + 2ATP

The pyruvate can then undergo aerobic or anaerobic respiration to generate energy. The Krebs Cycle is the aerobic route, and significantly more efficient that the alternative fermentation.

B. The two pyruvate molecules are then oxidized to two of Acetyl CoA with the release of carbon dioxide. The two acetyl groups of the Acetyl CoA are donated to Oxaloacetate in the presence of water to form Citrate.

C. Citrate then undergoes a number of chemical reactions to arrive back at Oxaloacetate again and the cycle starts all over again by reacting with more Acetyl CoA from Pyruvate and oxygen to form Citrate again. During the cycle more ATP is produced and electrons and other species are sent into the Electron Transfer Chain where most energy is generated.

During this cycle three major events occur:

1. During the various transformations of Citrate, specifically when Succinyl-CoA is converted to Succinate, one Guanosine Triphosphate group (GTP) is generated, which then donates a phosphate to Adenosine Diphosphate (ADP) to create the energy molecule Adenosine Triphosphate (ATP).

2. Over the whole cycle, three molecules of Nicotinamide Adenine Dinucleotide (NAD) are reduced to NADH that donates its electrons to the electron transport chain that is responsible for the generation of large quantities of ATP.

3. A molecule of Flavine Adenosine Dinucleotide (FAD) is reduced to FADH2, again donating its electrons to the electron transport system and the generation of energy.

Factor 2 and 3 are of more significance to energy generation than factor 1, and are the major means by which the Krebs Cycle generates energy.

Electron Transport Chain

The Krebs Cycle takes place within the mitochondria, structures that are contained in each of your body cells. Also within these mitochondria are a series of membranes that are very important in the generation of energy.

The major energy produced in your body cells comes from the Electron Transport Chain, a series of chemical reactions between an electron donor and an electron acceptor. Such reactions drive the transport of hydrogen ions (H+) across the membranes in the mitochondria.

The electron donors are species such as NADH, FADH2 and succinate and the electron acceptors are oxygen molecules. Hence the importance of oxygen in the process of aerobic respiration. The H+ ions are driven across the membranes and result in the conversion of ADP to ATP energy. In essence, the hydrogen atoms and electrons take part in a progressive chain of redox reactions, and at the end react with oxygen molecules and change it to water.

The Ultimate Products

Ultimately, through the whole chain and cycles of:

Glucose to pyruvate (glycolysis) Pyruvate to Acetyl CoA + CO2 (oxidation) Acetyl CoA to Citrate and the entire Krebs Cycle (reduction and oxidation) Krebs Cycle products to the Electron Transfer Chain Electron Transfer Chain to Water and ATP (redox) Final oxidation of hydrogen atoms to water

Basically: Glucose + Oxygen + 30ADP = Carbon Dioxide + Water + 30ATP

This is not balanced of course, and the ATP could be anything from 29 to 38, though 29.85 is the most accurate calculation to date. The entire process of glycolysis, oxidation, Krebs Cycle and Electron Transport Chain is powered by a series of enzymes and a small amount of ATP energy.

Glucose and oxygen are used up as the raw materials and ATP energy molecules are the product. It has been calculated that the total ATP yield obtained from one molecule of glucose lies between 29.5 and 30 molecules of ATP.

The Importance of the Krebs Cycle to Your Body

Were it not for the Krebs Cycle you would not be able to generate energy efficiently from your food. In particular, the carbohydrate content of your food. Carbohydrates are available in your diet from two sources: simple and complex carbohydrate foodstuffs such as cereals and grains, and fats and oils from animal and vegetable sources. They are also available from proteins, which are composed of amino acids at the head of the molecule with a carbohydrate tail.

Carbohydrates by definition contain only carbon, hydrogen and oxygen molecules, and can be converted to glucose within your body. Proteins can be deaminated and then the carbohydrate portion again converted to glucose. In fact, your body will initially use the carbohydrates in your diet as a source of glucose for its glycolysis to pyruvate, then the fatty tissue in your body, then the proteins will be deaminated so your body can get to the carbohydrate they contain.

Were it not for the Krebs Cycle, your body could not use the glucose as described above to generate energy. The only option open to it would be anaerobic respiration, or energy production in the absence of oxygen. ATP is still generated, but much less efficiently.

Anaerobic Respiration

Anaerobic respiration is basically respiration without oxygen. If there was no Krebs Cycle, then this is the only way your body would have to create energy.

Because no oxygen is actually needed for glycolysis or the Krebs Cycle, anaerobic respiration can proceed right to the end of the Electron Transport Chain. Then instead of oxygen being used as the terminal electron donor, it has to be another species such as nitrate or sulfate. Because the Reduction Potential of these species is much lower than that of oxygen, the amount of ATP energy produced is also much lower.

Your body tries to compensate by producing even more pyruvate and the excess is removed through lactic acid fermentation. Although this also generates ATP energy enough for short-term use, it leads ultimately to lactic acidosis and a reduction in pH, causing pain and vomiting.

Ultimately, if oxygen is not forthcoming, the brain runs short of the energy needed for it to work and you die. There is insufficient ATP generated from anaerobic respiration to maintain human life.

Conclusion

The Krebs Cycle is of critical importance for the production of energy: not just the energy to enable you to run fast, but to enable your metabolic processes to continue. It is needed for both aerobic and anaerobic respiration, and while lactic acid fermentation can be used by your muscle cells as a brief but effective means of generating short-term energy, it is insufficient to maintain the needs of your metabolism.

Without the Krebs Cycle, mammalian and most other animal life would not be viable and the world would be populated by anaerobic bacteria.

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Date: July 14, 2010 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glutathion, Antioxidants, And The Body

Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges.

Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis.

A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids.

The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell.

Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion.

Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well.

Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.

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Date: April 30, 2009 10:16 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Sweeteners Vs. Artificial Sweeteners

Artificial sweeteners are food additives intended to replace the sweetness of sugar without the calorie intake. There are also natural sweeteners that can replace sugar, so which should you choose? Natural sweeteners such as sugar, honey and grape juice are well known, although there are also the less well known, but much more effective, sucanat and stevia.

Sucanat is dried unrefined cane sugar, and unlike refined sugar retains the molasses. Stevia, on the other hand, is a shrub, native to Paraguay, the leaf of which contains a non-sucrose sweetener, 300 times the sweetness of sugar, and which is not absorbed by the body. It is a sweetener pure and simple, with no proven health issues. It is also Japan's most popular sugar substitute.

Artificial sweeteners have been known for many years, the first and best known being benzoic sulfanide, known to you as saccharin. The health risks of saccharin have been the subject of debate for over 100 years and have yet to be resolved. Studies had shown it to cause cancer in rats, and it was placed on a list of known or suspected carcinogens.

It has been banned for use in the USA, but that was lifted by the FDA in 1991, and in 2000 saccharin has no longer required a health warning label. The issue appears to have been resolved by rats metabolizing saccharin in a way not possible in humans. However, many are still suspicious of it, and if you don't trust a food additive then do not voluntarily consume it.

The top two artificial sweeteners in the USA are sucralose and aspartame. Sucralose, discovered in the UK in 1976, is the less emotive of the two, and is chemically the chlorocarbon trichlorogalactosucrose, produced by chlorination of sucrose and 600 times as sweet. It should be stressed that a chlorocarbon is totally different to a chlorinated hydrocarbon. It is generally considered safe to use, although it is very slow rate of degradation in waste water has raised concerns that concentrations could increase with increasing popularity of the sweetener.

According to' Sweet Deception', the book states sucralose to be discovered during the search for an insecticide, and is produced when sugar is treated with acetic anhydride, hydrogen chloride and trityl chloride among others in the presence of toluene, MIBK and dimethyl formamide among other solvents. Although marketed as coming from a natural source, it is anything but natural.

Aspartame was developed by G.D. Searle, and its approval by the FDA has been a matter of concern for many years. Promoted by Donald Rumsfeld, then CEO of Searle, he "called in his markers" to have the substance approved, which was not one of the more glorious moments in America's history.

It is used in over 6,000 products, most household names, yet was based on "inconclusive and incompetent science" according to detractors. In 1981, on the day of his inauguration, Ronald Regan suspended the powers of the FDA on aspartame, and then a month later appointed a new FDA head, Arthur Hayes, who immediately licensed the substance. Donald Rumsfeld was on President Regan's team.

There is a strong body of evidence that aspartame is toxic to humans, although the official evidence has discredit such studies. Recent evidence that linked aspartame to cancer has been stated as irrelevant to humans. In spite of the concerns, the substance has been approved, not only in the USA but also by the European Union. This might call into question the relevance of studies to humans, but many still believe that commercial considerations are behind these decisions.

In fact, an extensive study carried out by the Italian European Ramazzini Foundation, showed that aspartame can cause a significant increase in cancers and leukemias in rats at well below the doses allowed by the EU or the US. This substance required further study by bodies with no vested interest in the outcome.

Those that believe so point to the stevia situation. This natural sweetener is banned for use as a food additive in the EU, and cannot be sold as sweetener due to the FDA not recognizing it as such. It has also been banned in Hong Kong, even though it is the sweetener of choice in Japan, with no apparent side-effects becoming endemic in that country. The USA might not approve stevia as a sweetener, but it is considering lifting its ban on cyclamate.

Cyclamate was banned by the FDA due to tests on rats indicating a possibly carcinogenic effect, but no more positive than those on aspartame. Cyclamate is permitted in Canada, where saccharin is not, and also in the UK, but not throughout the EU.

It is obvious, then, looking at the various claims and counter-claims, and the conflicting legislation between civilized countries, that the artificial sweetener industry is wrought with uncertainty. In the past, it is almost certain that commercial considerations have come before the health of the nation, and that does not engender confidence.

In fact, the only sane approach to take at this time would be to avoid artificial sweeteners altogether, and stay natural. That is not to claim that natural products are safe to eat - far from it! Many of the most virulent poisons are natural, but the well-used natural sweeteners appear to be safer at this time than any of those artificially manufactured.

There might be objections to this where diabetes is concerned, and Canada, while banning saccharin for normal use, still allows it for use by diabetics. This is the one of the two major bodies that promotes the use of artificial sweeteners: the diabetic lobby and the weight loss lobby.

It is difficult to question the obesity and weight problem that America has while at the same time arguing against the use of artificial sweeteners. However, don't forget that stevia is widely used in Japan with no reported health problems, and stevia is a natural sweetener that is permitted for use as a food additive, and that is not absorbed by the body.

However, there is also a recent 2005 study that has indicated that diet drinks containing artificial sweeteners might fool your body into believing that the sweet taste is promising energy, and when it doesn't materialize, you feel hungry and eat more. This has been supported by animal studies.

These have shown convincingly that the sensation of sweetness induces the production of insulin with resulting hypoglycemia because there is no actual increase in blood sugar. This induces increased food intake. This has been proved with rats, and also proved was the fact that the natural response of eating less at the next meal, after sugary food, was gradually diminished in animals fed non-calorific sweeteners.

The choice is yours, but it would seem advisable to stick to natural sweeteners for the time being, at least until the studies carried out are in concurrence as opposed to offering conflicting results depending upon who is doing the testing.

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Buy Natural Sweeteners at Vitanet ®, LLC

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Date: April 23, 2009 01:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Protect The Liver with Glutathione And Cysteine

The tripeptide L-glutathione is synthesized in the body from L. glutamic acid, L-cysteine and glycine, a reaction that can occur in any cell of the body although it is essential that it also occurs in the liver. Should glutathione concentrations drop, they can be increased by supplementing with cysteine or any other of the three amino acids that are used in the biosynthesis of this important if substance

The tripeptide exists in two forms: the reduced form (GSH) which contains a sulfhydryl (SH) functional group attached to the cysteinyl part of the molecule, and the oxidized form glutathione disulfide (GSSG). As electrons are lost from the reduced form, two molecules combine to create a dimer formed by a disulfide bridge, the process which can be reversed through reduction of the GSSG. Such electrons are lost during its reaction with free radicals, in which the free radicals are neutralized by the donation of an electron from the oxidized version of glutathione.

The definition of a free radical is a molecule that is lacking one electron from an electronic pair. Its prime purpose is then to steal an electron from the nearest molecule to it. In doing so, it can not only destroy that molecule, but also destroy body cells and lead, not only to premature aging, but also to some potentially fatal conditions.

It is an unusual peptide in that it involves a link between the cysteine amino grouping and the carboxyl functional group of the glutamic acid. It is a powerful antioxidant, acting as an effective free radical scavenger and protecting the body cells from the effects of free radical oxidation. However, it is on its detoxification effect in the liver that we shall focus here prior to discussing some other uses to which the body puts glutathione in its two manifestations.

Much of the detoxification is connected with the thiol group in the molecule. Take mercury for example. The thiol grouping forms a strong Hg-sulfydryl chemical bond within the liver, in the form of a glutathione-mercury chelate. In this form mercury is unable to exert any toxic effect on the body and can be excreted in the normal manner. The same reactive pathway is followed by other heavy metals that can bond to thiol groupings. In this way L-glutathione can protect the liver from the effects of a number of toxic heavy metals such as cadmium and chromium.

This is an important property of the amino acid, particularly in industrial and urban environments where the population is more prone to exposure to heavy metals than their rural counterparts. However, the end result on the glutathione is that it is removed from the body, and, particularly with city dwellers, a supplement may be required to maintain a healthy concentration of this amino acid in the body and in particular in the liver. Therefore, although L-glutathione is not considered an essential amino acid, in that it is biosynthesized within the body, a supplement is sometimes required, particularly by those who live in large cities.

It is important to consider the form in which the glutathione supplement is administered. This is because of the presence of gamma-glutamyltranspeptidase within the digestive system. This enzyme appears to destroy L-glutathione before it can be absorbed in the intestine so normal oral forms of supplementation are likely to be ineffective. Possible forms of effective administration include buccal (between the cheek and teeth) and hypodermically.

An alternative means of supplementation is to take substances such as selenium, methionine, alpha-lipoic acid, vitamin C and glutamine that stimulate the biosynthesis of glutathione. Also, since the substance utilizes the raw materials of L-cysteine, glutamic acid and glycine in its intracellular production, supplementation with these amino acids should also help to produce L-glutathione.

That said, let's return to its antioxidant properties and its effect on the liver that contains the largest stocks of glutathione in the body. It is generally regarded as the most important antioxidant in the body. It protects cellular cytoplasm from oxidation by reducing disulfide groups and maintaining a highly reducing environment within the cytoplasm. It reacts with hydrogen peroxide and other oxidative agents, and is converted to the oxidized form GSSG. It is then reduced back to GSH through the combination of the reducing agent and an enzyme. The reducing agent is nicotinamide adenine dinucleotide phosphate (NADPH), the enzyme being glutathione reductase.

The implications that this strong reducing effect has on the liver are significant. Reduced GSH L-glutathione levels have been found in patients suffering from HIV, hepatitis C and other liver diseases. Supplementation with GSH has been found to restore normal levels of glutathione to the liver, and it has been demonstrated that the treatment has improved such conditions significantly.

Atherosclerosis is a condition of the arteries caused by the deposition of plaques formed from oxidized low-density lipoproteins, otherwise known as bad cholesterol. The strong antioxidant effect of GSH prevents this from LDLs from being oxidized and deposited on the arterial wall. There are other results of glutathione supplementation that indicate the effectiveness of antioxidants in the treatment of serious liver conditions, and there are no doubts that combating the effects of free radicals and oxidizing agents within the liver has a positive effect on many potentially serious liver diseases.

Many of these are exacerbated by the generation of free radicals by relatively modern pollution sources such as pesticides, petrol and diesel emissions, tobacco fumes and various other chemical emissions. A strong antioxidant such as L-glutathione cannot be anything other than an effective means of reducing the biological effect of these oxidants. It protects not only the liver but also the lungs and cardiovascular system.

For all these reasons a supplement consisting of L-glutathione or its constituent parts, glutamic acid, cysteine and glycine, provide significant protection against the stresses and strains of modern living. Increased pollution levels and heightened oxidative stress levels within the body are playing havoc with our body defenses, and GSH is an important one of them that can easily be enhanced by supplementation. There are no known reactions to L-glutathione supplementation, but pregnant women and babies should receive expert medical advice prior to taking it.

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Date: October 23, 2008 01:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Green Tea Extract

To understand the truth behind the medical claims for green tea and the antioxidant properties of EGCG, it is first necessary to have a close look at what green tea is, and why these claims are being made.

Green tea is a form of tea made from the leaves of the Carmellia Sinensis, a shrub that is native to China and has spread to other areas of Asia including Japan and the Middle East. Drinking it is believed to impart many health benefits, including the prevention of obesity, heart disease and some forms of cancer and it has been used in traditional Chinese medicine for over 400 years.

Tea is known to have been consumed in China for around 5,000 years, and used, not only in Chinese medicine, but also in that of Japan, Thailand and India for a number of ailments including regulating blood sugar, treating wounds and digestive problems. The drinking of green tea to benefit the heart and other vital organs is described in the Kissa Yojoki (Book of Tea), written in 1191 by Eisai, a Japanese Zen priest.

This two-part book talks about the various medicinal benefits of green tea, such as preventing fatigue, curing beriberi, quenching thirst, clearing the thoughts, maintaining health of the urinary tract and improving digestive problems. It also explains how to grow tea and how to prepare and use the leaves. The methods of treatment of various ailments and medical conditions are described in the second part of the book.

The active ingredients in green tea are catechins, polyphenols with strong anti-oxidant properties. Antioxidants are important components of your diet due to their effect on free radicals. These are small molecules, generally oxygenated, such the superoxide cation and hydrogen peroxide that are generated during normal metabolic processes and also ingested in pollutants such as traffic and factory fumes and insecticides. Free radicals are also formed by the effect of the ultra-violet component of sunlight on your skin and other tissues.

The effect of free radicals on your body can be devastating, and they not only destroy cell membranes but also oxidize such molecules as the low density lipids (LDL) that carry cholesterol around your bloodstream. This allows the LDLs to be absorbed by the white blood cells and then deposited as fatty plaques in the walls of your arteries. The end result is a thickening and hardening of the arteries that leads to a condition known as atherosclerosis, where the blood supply to the brain and heart muscle is restricted, which can in turn lead to strokes and heart disease.

Their effect on your cells is to cause cancer and premature aging, among others, and free radicals are also believed to play a part in conditions such as Alzheimer’s and Parkinson’s disease and also inflammatory diseases such as arthritis and diabetes. They can also cause damage to your DNA.

It is essential, therefore, that these free radicals are destroyed as quickly as they are generated, and that is what antioxidants do. You might be more familiar with the antioxidants Vitamins A, C and E, and phytochemicals such as flavonoids and carotenoids, but there are many substances available to you that are even more powerful such as the polyphenols found in green tea.

Epigallocatechin gallate (EGCG) is the most powerful of these with antioxidant properties at least twenty five times that of Vitamin E, and 100 times that of Vitamin C. EGCG comprises around 10-50% of the total catechin content of the tea and studies indicate that it likely helps to protect against DNA damage by free radicals, to protect against oxidation of LDL, provide protection against the damage of ultra-violet radiation and to protect you from the free radicals that are generated by smoking tobacco and general airborne pollution.

There are suggestions that the bioavailability of EGCG can be increased by consuming black pepper when drinking green tea, possibly due to the presence of piperine in the pepper. The piperine appears to retard the intestinal glucuronidation of EGCG and so allow more of it to be absorbed as opposed to excreted. So if you are using green tea for health reasons, spice up your food with a small amount of black pepper - that's all it needs. You don't have to smother your food in it! It should be stressed that these tests were carried out on animals, although the biochemistry involved is much the same.

The oxidation of fat by your metabolism to provide energy is a very important factor in weight control. If the contribution of the fats you ingest to the energy generated by your metabolism is low, then the fats can go on to be deposited in your body. This is not only unsightly, in that it can basically make you look 'fat', but is also dangerous to your health. Fat deposits around your midriff and round the major organs of your body can be extremely damaging and a severe risk to your health.

It has been shown by a recent study in the UK (Birmingham University) that those taking green tree extract displayed a 17% increase in fat oxidation over those given a placebo. Not only that, but the ratio of fat oxidation to the overall energy expenditure showed a similar differential between the study and the control group. This provides evidence of green tea extract being able to control your weight by burning fat, and also to improve the tolerance to glucose and sensitivity to insulin of healthy people.

Many other health claims have been made for green tea extract, although many of these have little, if any, scientific basis. Among these are the claims that it can treat multiple sclerosis and be used to treat cancer, although claims that it can prevent the destruction of cell membranes due to its oxidative effect are supported by the biochemistry, if not the medical proof. There are cases where theoretical biochemistry can explain many of the applications of ancient remedies without needing modern day studies to support it.

Some of the research supporting the green tea theories include:

1. In 2006, a study was announced that had followed over 40,500 Japanese men and women, aged between 40 and 79, that had no history of coronary heart disease, stroke or cancer starting in 1994. It was found that those who drank at least 5 cups of tea per day had a 16% lower risk of dying from any cause and a 26% less risk of dying from cardiovascular disease than those that drank less than one cup of tea each day. Since cardiovascular disease and cancer are the major causes of death world-wide, these are significant results.

2. Again in 2006, it was reported in the American Journal of Clinical Nutrition that studies indicated that a higher consumption of green tea was associated with a reduction in human mental impairment when compared to the average.

3. Yale University School of Medicine reported later that year that, in spite of smoking more than their western counterparts, Asians suffered lower rates of cancer and heart disease, and put that down to them drinking over 4 pints of green tea daily. It was the polyphenol content of green tea and its antioxidant effect that was proposed for this result, known commonly as the 'Asian paradox'. A specific reason given for this was the antioxidant effect preventing the oxidation of LDL cholesterol, and its subsequent deposition in the artery walls.

4. Another component of green tea is the amino acid L-Theanine that promotes relaxation, and it is believed that this could help to fight stress by inhibiting the excitation of cortical neurons.

There is a lot more evidence for the health benefits of green tea, and once again it appears that the ancients have been proved correct. Perhaps we should pay more attention to ancient remedies, although without the proper evidence much of it is ignored - for the time being at least. Green tea, however, has generally been accepted due to the research and studies carried out on ECGC (Epigallocatechin gallate) and in additional to the traditional form, is also available as a dietary supplement.

--
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Date: October 22, 2008 04:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Green Coffee Bean Extract

It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs.

The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition.

However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here.

The Free Radical Theory of Aging

Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them.

Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging.

Free radicals are generated in the body in four different ways:

1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher.

2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes.

3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting.

4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products.

In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body.

So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell.

Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron.

Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals.

It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol.

The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level.

Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging.

A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life.

There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.

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Date: October 16, 2008 01:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lower Blood Sugar

Many people struggle to control their weight. However, while they are going on and off various diets, they fail to realize that they are also struggling to control blood sugar. Actually, the cause of blood-sugar problems may be weight problems, as being overweight and having blood sugar problems tend to go hand in hand. Too many blood sugar swings during the day tend to increase hunger jags, snacking, and overeating. When you overeat, you’re much more likely to add on the pounds, setting the stage for obesity, pre-diabetes, and full blown diabetes.

Sadly, both pre-diabetes and overweight have become modern epidemics that are out of control, with two of every three Americans being overweight and over 100 million people having some signs of pre-diabetes. Both of these illnesses are nutritional disorders that result from eating too many unhealthful foods. However, there is good news: you can reverse pre-diabetes and control your weight.

One can self-diagnose pre-diabetes by looking for the most visible symptom: being chubby or fat around the waist. Other clues are cravings sweets and starchy foods, not being hungry at breakfast, and feeling tired or mentally fuzzy after lunch. Many physicians diagnose pre-diabetes when a patient’s fasting blood sugar falls between 100 and 124 mg/dl. There are several dietary factors that significantly increase the risk of overweight. Some of these being: too many calories, too many refined carbs, especially sugars, and too many unhealthful oils.

The average woman needs about 1,600 calories and the typical man needs about 2,000 calories daily, but the average American now consumes 3,900 calories each day, making it difficult to burn off all these calories and causing the accumulation of body fat. Because most excess calories take form of refined carbs and sugars, which are digested rapidly, rapid or extreme spikes in blood sugar levels, elevated insulin levels, and bouts of hunger result, which stimulate low blood sugar. Trans fats, which are found in partially hydrogenated vegetable oils, interfere with the body’s processing of fats and often lead to weight gain. Most of these problematic calories are found in fast foods, microwave foods, and other types of convenience foods, which are all best if they are avoided.

Even though pre-diabetes can be scary, it’s actually an opportunity to improve your eating habits and regain your health. To improve your health you can emphasize quality protein, emphasize high-fiber vegetables and fruits, include grapefruit in your diet, use more vinegar, and add some cinnamon. Since protein stabilizes and safely lowers blood sugar levels, be sure to start each day with some protein with breakfast and eat a little protein with each meal.

Most veggies and fruits are rich in fiber, which helps to lower blood sugar, so opt for salads and steamed broccoli while avoiding crutons, potatoes, bananas, and pears. Despite the calories, eating fresh grapefruit can help in weight reduction. The acetic acid in vinegar can also help to improve blood sugar and insulin levels, reduce appetite, and help with weight loss. Adding cinnamon has also been shown to reduce blood sugar levels. There are also several supplements that have exceptional value in improving insulin function or lowering blood sugar levels. These include lipoic acid, chromium, silymarin, omega-3 fish oils, vitamin D, and Pycnogenol.

You can also enhance the benefits of diet and supplements by increasing your physical activity as it helps build muscle and burn blood sugar and fat. Tackling pre-diabetes can not only reduce your long-term risk for health problems, such as heart disease and Alzheimer’s disease, but also can allow you to quickly gain more energy and feel less post-meal fatigue.

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Date: September 16, 2008 08:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Essential Fatty Acids

A lot of people tend to shy away from anything that has the word fatty involved with it, thinking that it will cause them to gain unnecessary weight. What a lot of people don’t know is that there are good fats and bad fats. The beneficial ones actually can help decrease the desire for food and for harmful fats. Fats are essential to health, as they help to balance the body’s chemistry and provide padding for the vital organs in the body. Fats give a source of energy for body processes and also help with the transportation and absorption of vitamins A, D, E, and K, which are all fat soluble.

There are three main categories of fats: saturated fats, unsaturated fats, and essential fats. Saturated fats are made of carbon, hydrogen, and oxygen molecules. The carbon atoms from fatty acids hold together in a chain-like fashion and they can attach a hydrogen atom to them. When each potential place for a hydrogen atom has been filled and there is no more room for any more hydrogen atoms, these fats are considered saturated. The fat will be harder or thicker in consistancy the longer the chain.

These types of fatty acids are found in red meat, butter, cheese, sour cream, palm kernel, and coconut oils. When someone has a diet that is high in saturated fats, these fats clump together in the body and form deposits that lodge in cells, organs, and blood vessels and can lead to many health problems like obesity, heart disease, and breast and colon cancer.

Unsaturated fats are called this because at least two adjacent carbon atoms on a chain are not attached to hydrogen atoms. When at least two pairs of carbon atoms are empty, it is known as a polyunsaturated fatty acid. The more saturated the fat, the more easily it will stay hard at room temperature.

Essential fatty acids are crucial nutritional compounds that our bodies need in order to perform many functions. They can be found in the seeds of plants and in the oils of cold-water fish. Essential fatty acids can not be made in the body, so they must be found in a supplement or in the diet. Many factors, which include stress, allergies, disease, and diet high in fried foods, can increase the body’s need for essential fatty acids.

Fatty acids are the basic building blocks of all fats. A fatty acid is considered essential if the body is unable to synthesize it and the only way it can be obtained is through diet. Additionally, it is considered essential if a deficiency will cause disease. A deficiency of fatty acids can cause poor reproduction, lowered immunity, rough and dry skin, and slow growth.

Essential fatty acids are vital for many functions including: lowering triglyceride levels; helping to eradicate plaque from the walls of arteries; lowering blood pressure; altering the production of leukotrienes; constructing body membranes; helping strengthen cell and capillary structures; prolonging blood-clotting time, which helps wounds to heal; helping the body manufacture hemoglobin; assisting in the manufacture of cholesterol; preventing the growth of bacteria and viruses assisting in the functions of glands and hormones.

Essential fats nourish the skin, hair, and nails; increasing the rate at which the body burns fat; helping the body maintain proper temperature; assisting in the body’s production of electrical currents that are vital for a regular heartbeat; and acting as a precursor to the production of prostaglandins. It is essential that everybody obtain good fat in their diet to maintain health, if one can not eat the proper foods, supplement forms of essential fatty acids are available.



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Date: August 23, 2008 11:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acidophilus

Acidophilus is correctly named Lactobacillus acidophilus, and is one species of Lacobacillus used commercially in the preparation of certain types of yoghurt. The name refers to the fact it is found in milk (lacto), is rod-like in shape like many bacteria (bacillus) and it likes acidic conditions (acidophilus). It not only likes them, but creates them.

In fact, acidophilus thrives at a pH of 4-5 or less, and occurs naturally in the gastrointestinal tract of humans and animals, and also the mouth and vagina. It ferments milk to lactic acid, and dies in the presence of sunlight, excessive moisture and at high temperatures. Some, but not all, strains are probiotic, or ‘friendly’ bacteria that aid digestion and help to protect against harmful bacteria and their toxic emissions.

The fermentation of nutrients by friendly bacteria produce acids, such as the lactic acid previously referred to, hydrogen peroxide and other substances hostile to harmful organisms, and also reduces the population of harmful bacteria by competing for their food. There are additional health benefits that shall be discussed later, but first some comments about the stability of acidophilus to heat.

The growth rate of acidophilus reaches an optimum at around 36-37F (2.2C), and it tends to die off at temperatures much above this over a period of time. It also tends to be sensitive to oxygen and moisture, and if exposed to heat, moisture and oxygen, a supplement will lose its potency over time. This is true of all such supplements, and after purchase must be quickly refrigerated. It is possible, however, to purchase stabilized forms of acidophilus that die off slower than normal. This extra resistance is built in during the manufacturing process, and many forms of acidophilus claim to be stable. Although there will never be a truly stable form of the probiotic, these stabilized versions do last longer than those not claimed to be so.

During manufacture, the bacteria are first concentrated by removing the excess liquid by means of sedimentation, ultra-filtration, reverse osmosis and centrifuging. A substance is then added to protect the bacteria from the shock of freezing and the acidophilus freeze dried. A stabilizer is then added to maintain its properties between freezing and consumption.

It has also been found that bacteria grown at higher pH levels last longer than those at lower pH. The packaging is also important, and since the bacteria are sensitive to oxygen, nitrogen flushing the bottles will improve the stability of the product. Glass bottles are less porous than plastic, and so is the preferred packaging material for maximum stability and life. Another factor is refrigeration. If you keep the bottle in the fridge it was last a lot longer than at room temperature, but take care not to freeze it since acidophilus does not freeze well. If it is not refrigerated then it will quickly lose its potency.

The form in which you take the supplement is immaterial regarding the potency: at least initially. However, through time the powder will become less potent quicker, because it will adsorb oxygen and moisture. Otherwise the form in which it used is immaterial. So, yes, acidophilus can be stabilized, but only for a while, and if allowed to warm up to room temperature in the presence of oxygen will quickly degrade, although this takes more than just a day or two.

Many health benefits are claimed for Lactobacillus acidophilus, although your daily consumption to achieve these should be at least 2 billion CFU, and preferably 5 billion. You can also fortify the bacteria with a prebiotic of fructooligosaccharides (FOS). These provide nutrition for the acidophilus and accelerate its growth.

One thing to be careful of is assuming that yoghurt contains acidophilus. It does not contain sufficient to be of benefit to you. Commercial yoghurt acidifies over time and kills off the bacteria, so commercial yoghurt sitting on a supermarket shelf has very little beneficial bacterial content. Natural yoghurt is better, and certainly contains beneficial bacteria, but not enough to make a significant difference. A supplement is therefore needed if you are to keep your intestinal tract sufficiently healthy. If you cannot take dairy products, acidophilus is available in non-dairy form. The major health benefits they impart are:

1. Digestive Problems.

Acidophilus can control many types of digestive disorder, particularly traveler’s diarrhea. In fact if you are traveling to countries where drinking water might be a problem, also take some acidophilus and this will tend to prevent you from becoming ill. Even if you drink bottled water, there are still washed salads, beverages made with local water and showers and the like whereby you could ingest some dodgy water.

2. Constipation

Acidophilus, especially when supported by FOS, helps both to hydrate the feces, and improve their transport through the colon, an also to improve the general health and well-being of your entire intestinal system.

3. Yeast Infections (Candidiasis)

Acidophilus possess antifungal properties that kill off yeasts, particularly Candida albicans found in the vagina. This is due to the lactic acid produced by the bacteria, and there is evidence that gastrointestinal yeasts are affected in the same way by the oral probiotic. Furthermore, when bacteria and yeasts are killed off by medication, including friendly bacteria, the sites they occupied on the intestinal walls become free and acidophilus should be present to take these up and prevent any more yeast or bacterial infections. That is one reason why probiotics should be taken immediately after a course of antibiotic treatment.

4. Immune System Support

Lactobacillus acidophilus is believed to modify the balance of microbes in the intestine so as to lead to an enhanced production of antibodies, and white blood cells with increased phagocytic activity. The bacteria also appear to have some reducing properties, which can also give support to the immune system through the resultant antioxidant properties.

However, by far the most important property of probiotics are their properties in acidifying the intestinal tract, and so rendering them less attractive to harmful pathogens, and in producing hydrogen peroxide which has a similar effect. They also produce natural antibiotics, and there is now doubt that a supplement of acidophilus will provide you with several health benefits and also make you feel fitter and more alert.

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Date: August 18, 2008 12:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coconut Oil

Whether coconut oil is good for weight loss or not, it is becoming an increasingly popular component of a weight loss diet. So how justified is this in view the fact that fats and oils are not normally regarded as being the best form of food to take if you want to lose weight?

Apart from any other considerations, fats are actually very important components of any diet. Consider, for example, how many vitamins are fat soluble: vitamins A, D, E and K are all fat soluble, and without fats in your diet vitamins would not be able to circulate and be taken to where they do most good. Fats are also essential building blocks for hormones and cell membranes. In short, you cannot survive without fats. Coconut oil is a fat.

In referring to coconut oil here, we are discussing virgin oil, not the refined form that is high in cholesterol. Refined, or processed coconut oils, is hydrogenated, which renders it more in nature to the longer chain fatty acids. Virgin coconut oil contains what are known as medium chain fatty acids (MCFA), which are easily metabolized by your liver into energy.

The longer chain fatty acids, also called triglycerides, are not easily broken down into smaller components, and tend to be stored in the body as fat. This fat can be particularly dangerous if stored round the midriff, and so long chain fatty acids are dangerous to your health. This does not apply to MCFAs, and a possible mechanism for this is discussed later.

An inability to distinguish between the different types of fats and oils in your diet is largely due to a lack of education in the chemistry of fats, and the lumping together of all fats and oils under the 'fatty' flag. Perhaps it is the use of the word 'fat' for the overweight condition and the fact that the triglycerides and other chemicals are known generically as 'fats' that triggers a connection between the two, but although this is logical, and in some cases justified, it is not always the case. There are fats and fats, just as there are lubricating oils and greases, and edible cooking oils and greases.

The fatty acids in coconut oil are composed of relative small carbon chain lengths. Caprylic acid and capric acid contain 8 and 10 carbon atoms in the backbone compared to the 18 of the stearic acid that is commonly contained in animal fats. The longer the carbon chain in the molecule, the more difficult it is to break down, and the more likely it is to be stored in the body as a dense fatty deposit that places a strain on the heart.

Due to the shorter chain length the medium chain fatty acids hold less energy per unit weight. Apart from any other reasons then, coconut oil contains fewer calories than other fats and so if used as the bulk of your fat requirement, will be less liable to generate body fat. Not only that, but as inferred earlier, due to the smaller molecule these calories are more readily released as energy for use by your body rather than stored unused.

However, that is not the whole story on either count: coconut contains saturated fats, and also monounsaturated and polyunsaturated fats, although in small quantities. These, however, are present in only small amounts, although would still be expected to undergo oxidation and produce the rancid taste commonly found in aged unsaturated oils and fats. However, even after a year this does not happen, which indicates that coconut oil possesses some form of antioxidant properties. This is confirmed by the fact that people eating a diet rich in coconut oil has less of a need for the strong oil-soluble antioxidant vitamin E.

In fact, the metabolism of fats is usually connected with the carnitine transport system in the mitochondria, although the shorter chain fatty acids do not need carnitine for their metabolism. What happens then is that because carnitine promotes oxidation during stress, and causes oxidative damage to body cells, its absence in metabolism of coconut oil fatty acids results in a reduction in the oxidation that degrades unsaturated fats. Hence the lack of rancidity.

Taking this further, then, this lack of oxidation infers that those that take a diet rich in coconut oil (for example using it for cooking rather than animal and vegetable oils containing longer chain fatty acids) should be partially protected against cell oxidation in general. Oxidative effects such as aging, cardiovascular diseases and some cancers should be reduced, and studies have shown this to be the case. Those consuming coconut oil rather than other oils tend to age more slowly, suffer less from heart disease and tend to experience fewer incidences of cancer.

With regard specifically to weight loss, it is believed that consumption of medium chain triglycerides, as opposed to longer chain triglycerides, results in a higher rate of thermogenesis, or the conversion of carbohydrates to energy (fats are also carbohydrates). The first step in this process requires the presence of Coenzyme A in the form of the enzyme acyl-CoA-dehydrogenase, and measurement of the activity of this enzyme has indicated that medium chain triglycerides exhibit much higher expenditure of energy than the metabolism of long chain triglycerides when being converted to fatty tissue. However, though the energy used up in this reaction, known as lipogenesis, was higher, the formation of fatty tissue was the same.

Hence, MCA uses more energy to produce the same amount of fat as LCA, and therefore, although more energy is used up, no new fat is generated by the liver. Since your dietary fat intake can ultimately have only three fates: burned as energy, stored as the emergency energy source glycogen, or deposited as fat, then it is logical that the more energy generated then the less fat will be stored.

In this way, coconut oil, with a high content of medium chain fatty acids, has a scientific explanation for causing weight reduction when used as a source of fat in the diet rather than animal or other vegetable fats or oils. It is converted to energy rather than fatty tissue, and if you exercise to use up that energy then your weight loss can be significant.

What this theory also states, however, is that coconut oil should be used as a replacement for other fats, and not in addition to it. If you take coconut oil in addition to your normal diet, do not expect to see results.

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Date: July 25, 2008 10:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium D Glucarate

Studies have found that D-glucarate has therapeutic actions; among these are cancer prevention and serum cholesterol reduction. However, its most impressive property could be its ability to quickly detoxify the body of both artificial and natural toxins which can be potentially harmful. These toxins can be neutralized in many ways, with glucuronidation being one those ways. The process of glucuronidation involves using the liver to neutralize chemical carcinogens and steroidal hormones including estrogen. Once a toxin has been glucuronidated in the liver, it goes to the bile and is eventually eliminated from the body in the stool.

Beta-glucuronidase is an enzyme that is produced in the gut by unfriendly bacteria which can actually inhibit this process by chemically splitting a glucuronidated toxin before it is able to be eliminated in the stool. This unbound toxin can come into contact with the bowel lining where it can be reabsorbed and the whole process will be repeated. When a situation like this happens, cells are exposed, once again, to the chemical and the liver can become overworked. Thankfully, if D-glucarate is present, beta-glucuronidase is inhibited, resulting in a flawless glucuronidation in the body.

These findings suggest that taking D-glucarate orally as a supplement can provide us with the increased ability to efficiently and rapidly rid our bodies of toxins through problem-free glucuronidation. Additionally, D-glucarate does not work like an antioxidant, which neutralizes free radicals, but instead actually forms a type of bond with harmful compounds to enhance their rapid removal from the body. Some of the organs that can be especially toxin-sensitive are the breast, prostate, liver, lung, and kidney, therefore, they can greatly benefit from this process. These organs can be most damaged by the continued exposure to poisons and carcinogens.

Because our generation, more than that of any other, is exposure to a great number of potentially harmful environmental pollutants, our contact with carcinogens increased exponentially. Just some of the cancer-causing agents include cigarette smoke, pesticides, radon, hormonally-fattened meats, diagnostic and therapeutic x-rays, gamma radiation, trans-fatty acids, alcohol, poor diets, xeno-estrogen, herbicides, smog, car exhaust, certain prescription drugs, ultra-violet light, rancid foods, saturated / hydrogenated fats, some food/water supplies, and food preservatives. Although a lot of us have taken necessary measures to protect ourselves from exposure to the substances listed, it is inevitable that we will consistently take chemicals that can prompt the growth of cancer into our bodies.

Additionally, our own hormones can be a threat if they are not efficiently metabolized and excreted from our body. One study found that Glucarate supplementation amplifies the process by which carcinogens and hormones are removed from the body, while D-glucarate can exert a positive effect on different stages of the carcinogenic process. It has been found that lower cancer rates in some populations could be attributed to their consumptions of foods that are rich in D-glucaric acid, self-medicated with D-glucarate, or combine D-glucarate supplementation with other chemopreventive agents.

Either way, the protective function of glucarate in the body’s natural cancer prevention mechanisms has been established for long periods of time, while other recent studies have indicated that the use of glucarate could potentially present a fifty percent decrease in tumor incidence.

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Date: July 22, 2008 01:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: DHA

DHA is a fatty acid that is essential for many body processes and structures. Fatty acids are the building blocks that create lipids, which are important nutrients that make up 25 to 45 percent of total body energy for most of those who are living in industrialized countries. The majority of dietary fatty acids are made from dairy products, meat, margarine, and vegetable oils.

Lipids are important because they store and transport energy from one part of the body to another and they also insulate and mechanically protect certain parts of the body. Any fat that is eaten is converted by the body into fatty acids, where it is then burned for energy, stored, or synthesized into other acids which are called prostaglandins. Some fatty acids are also vital structural components of cell membranes. DHA is part of a special class of highly concentrated, long-chained, polyunsaturated fatty acids called omega-3 fatty acids. Omega-3 fatty acids are looked at as one of the most fundamental molecules in the structure and activity of the membranes of all cells. They have a huge influence on the production of cellular regulatory compounds which are known as eicosanoids. They also are highly specialized in their function in neurological tissues, especially the retina of the eye. It is also very likely that omega-3s have specific and beneficial effects on the heart muscle, while they also influence the production of substances that control immune responses.

Fatty acids are short-chained, medium-chained, or long chained. Short-chain fatty acids are water-soluble and absorbed directly from the intestine into the bloodstream. They are generally used for immediate energy and can be found most abundantly in dairy products. Long-chained fatty acids are more emphasized when it comes to health concerns as they are stored in cell membranes and have a huge affect on membrane protein function. Their behavior in tissue membrane is what makes them greatly influential in health.

Besides the length of the chain, fatty acids are also described by their saturation. Saturation means how many hydrogen atoms the fatty acid carries. Fatty acids that carry as many hydrogen atoms as they can are called saturated fatty acids, while those that lose a pair of hydrogen atoms become unsaturated. This loss of hydrogen atoms creates a double bond between the two carbon atoms on either side of the missing hydrogen atoms. Those fatty acids that have one double bond are called monounsaturated fatty acids, while those with two or more double bonds are called polyunsaturated fatty acids. Most omega-3 fatty acids are highly unsaturated and have five or more double bonds.

EPA and alpha-linolenic acid are most commonly found in plant sources. DHA and EPA are made in phytoplankton, which is consumed by fish, mollusks, and crustaceans. The above reason is why these two essential fatty acids are found mainly in the aquatic food chain. LNA and EPA cannot substitute for DHA in all metabolic functions, even though DHA and EPA are more able to cover for each other in certain metabolic functions. It has been found that LNA is less effective than EPA which is less effective than DHA in enriching tissues, meaning that food sources such as vegetables and seed oils are not as good of sources than sea foods or other foods that are enriched with DHA and EPA. DHA in itself provides most of the health benefits displayed in research, to take essential oils that contain no DHA would limit the health benefits discussed above and from other sources. Have you had your DHA today?

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Date: June 28, 2008 11:46 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Beta Sitosterol

Phytosterols are the group of naturally occurring plant compounds which have two significant health benefits. First of all, phytosterols reduce blood levels of total cholesterol and the “bad” LDL cholesterol. Second, which is particularly good for men, phytosterols can reduce symptoms of benign enlarged prostate. These naturally occurring plant compounds are added to many common cholesterol-reducing foods, but can also be taken as capsules. Even though the word phytosterol may sound a little like steroid, phytosterols do not have any hormonal activity. Phytosterols are known by a large variety of names such as plant sterols, free sterols, and sterol esters. A related group of compounds, which are called stanols, are gathered from trees, not from plants.

Phytosterols chemically consist of beta-sitosterol, campesterol, and stigmasterol. The structure of phytosterols is similar to that of cholesterol, but is poorly absorbed. Because of these traits, phytosterols function as cholesterol blockers by reducing the absorption of cholesterol from food and re-absorption of cholesterol from the intestine, which ultimately leads to lower levels of blood fats. Actually, the U.S. Food and Drug Administration now allows companies to claim that phytosterols-containing products are able to lower the risk of heart disease. Phytosterols can also be found in a large variety of plant foods, which includes fruits, vegetables, herbs, nuts, grains, and cooking oils. Additionally, saw palmetto, which is an herb that is commonly used to treat benign prostate enlargement, is rich in phytosterols, especially beta-sitosterol.

Many studies have been done that show the abilities of phytosterols supplements to reduce cholesterol levels significantly. One study conducted at East Tennessee State University, researched both sterol esters and placebos on the same group of sixteen people. The results showed a five percent decrease in total cholesterol and four percent decrease in LDL cholesterol after taking a modest dose of sterol esters for four weeks. Additionally, triglyceride levels decreased by nine percent while HDL cholesterol increased by four percent. Another study in which 2.6 grams of phytosterols were taken daily for 12 weeks resulted in a decrease of 3.5 percent in total cholesterol and 5 percent in LDL cholesterol. Due to this, it is suggested that those wishing to supplement in order to improve cholesterol levels should take 1.3 to 3 grams of sterol esters daily.

Several other studies have found that supplements of beta-sitosterol can significantly reduce urinary symptoms of benign prostatic hyperplasia, which commonly affects men ages 50 and older. The benefits can be long term to those men who continue taking supplements of about 200 mg of beta-sitosterol three times daily.

For those people with moderately elevated cholesterol, phytosterols can be an ideal natural alternative to drugs. Even those people who are already taking cholesterol-lowering drugs can benefit by phytosterols ability to further enhance the benefits of medications. In order to lower cholesterol, it also helps to reduce the intake of hydrogenated vegetable oils and refined sugars and starches, along with increasing physical activity. Dosages between 1.3 and 3 grams daily are likely to reduce cholesterol and LDL-cholesterol levels. The higher dosage is linked to greater reductions in cholesterol. Take phytosterols capsules along with food, for best results.

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Date: May 15, 2008 01:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Copper

Copper is an essential trace mineral necessary for life, and it is necessary for the proper function of certain enzymes that allow certain biochemical functions of the body to take place. Without copper neither plant nor animal life would be possible.

Dietary sources include nuts, grains, seeds, beans and other vegetable protein sources. Although it is also obtained from animal sources, these tend to be rich in zinc, and for reasons that will be discussed shortly, the presence of zinc can deplete copper absorption. Other common sources are copper cooking utensils and drinking water from copper pipes. After digestion, copper is absorbed into the body through the stomach and the small intestine. It is also possible for copper to be absorbed through the skin from copper bracelets.

Once absorbed, copper is bound to albumin and taken by the blood to the liver, where it is bound to a plasma protein known as ceruloplasmin. Among the enzymes with which copper is associated as a ‘helper’ are Cytochrome C oxidase, used in the conversion of glucose to energy, Dopamine hydroxylase, an essential component in the biochemical production of adrenaline, and superoxidase dismutase, that protects against the oxidative damage of cell tissue. Of particular benefit are its anti-inflammatory and antioxidant properties, and its role in energy production. Because of its antioxidant effect, copper could well play a very important role in protecting against atherosclerosis, and cardiovascular disease, the ravaging effects of free radicals on body cells and also certain forms of cancer.

Copper is also important in electron transport, and is responsible for the blue coloration of the blood of most molluscs and many arthropods. This is because rather than hemoglobin, these animals use the copper-based hemocyanin for oxygen transport in the blood. Rather than the iron-containing hemoglobin making the blood of these creatures red as it is with mammals, theirs is blue due to the hemocyanin. Copper salts are generally green and blue, as are the blue copper proteins plastocyanin and azurin.

So how is copper used by the body? It is, after all, fairly toxic, as little as 30 grams being fatal to humans, bringing on similar symptoms to those of arsenic poisoning. It is in fact the reason for its toxicity that also renders it so useful to the body. The toxicity is largely due to the ability of copper to accept and donate electrons as it changes between oxidation states. This results in the generation of very reactive radicals that can cause severe oxidative stress. The complete reason for its toxicity has yet to be determined, but the stress caused to body cells by free radical oxidation is a very serious condition.

It is this rapid change in its oxidation state that is valuable to the enzymes with which it is associated. The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase. In doing so the copper is converted to the monovalent state.

It also helps to aid in the production of the strong antioxidant Superoxide dismutase (SOD). What this enzyme does is to catalyze the formation of oxygen and hydrogen peroxide by the dismutation of superoxide, a negative ion consisting of two oxygen atoms and a free electron, and hence a very powerful free radical. Dismutation is the simultaneous oxidation and reduction of the species, rendering the free radical relatively harmless. This type of action on free radicals is a very powerful one, and essential in the body’s fight against such free radical species that are so dangerous to animal cells.

SOD exists in more than one form, and can also contain zinc, manganese and nickel in addition to copper. The internal fluid (cytosol) of practically all eukaryotic cells (cells containing a nucleus) contain a form of Superoxide dismutase dependent on copper and zinc, while most mitochondria contain an SOD with manganese.

Another of the important uses that your body can find for copper lies in the production of hemoglobin. This is because copper is needed for the storage and release of iron to produce hemoglobin, the protein in red blood cells. It is believed that ceruloplasmin is involved in the catalytic formation of ferric iron by the oxidation of ferrous iron, so allowing the iron to be attached to a protein that transfers it round the body to enable its use in the biosynthesis of various ferrous compounds, especially of hemoglobin.

Copper bracelets are commonly worn by arthritis sufferers, and there is a scientific explanation for that. As previously inferred, it is believed to be possible to absorb copper through the skin and copper is known to be involved in the formation of collagen and is a commonly used treatment for arthritis and osteoporosis. Part of its effect on arthritis is likely due to the antioxidant effect of the SOD that helps to reduce the inflammation at arthritis sites.

Although a deficiency in copper can lead to serious health problems, an excess is also harmful. Potential conditions include neurological problems, liver damage and bone abnormalities, although deficiency is far more common because of the competition between copper and zinc. Zinc is a copper antagonist, as is iron and manganese, and copper imbalances can be moderated by the use of these as supplements.

The symptoms of a copper deficiency include fatigue, hair loss, stunted growth, anorexia and a host of other conditions. Luckily, however, a deficiency is rare and most people receive a sufficient amount of copper in their diet. Supplements are available to ensure an adequate intake.

There is still much to be learned about the interaction between copper and enzymes, and there is also a great deal still to be learned of its role in human metabolism and biochemistry than is currently known. However, sufficient is known already for us to be certain that copper is a very important trace element and that we should be certain that our intake is sufficient, given that zinc iron and manganese compete to prevent copper being absorbed by the body.

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Date: May 12, 2008 11:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Colostrum

All female mammals, including humans, produce colostrum soon after giving birth, and before proper milk is produced. It is a milk-like substance that provides newly born infants with a boost to their immune system and gives immediate protection against the germs with which they are about to come into contact.

It also, incidentally, promotes the child’s first bowel movement to rid it of the large amount of dead blood cells created when it’s blood supply was drastically reduced after the severing of the umbilical supply.

It is now believed that colostrum will help not only newly born infants, but also grown adults. If your immune system is weak or you are suffering from a condition that could be helped by a boost to your immune system, colostrum might be what you need to help you fight off what is ailing you. This has become clear after the way that colostrum works has been established.

Transfer factors were discovered in 1949 by Dr. H. Sherwood Lawrence of the New York University School of Medicine. He found that when he injected an extract of the leukocytes of somebody that had previously been infected with tuberculosis, the natural immunity was transferred from the donor to the recipient. He called this extract the ‘transfer factor’, and a means of transferring immune response factors between people was born.

However, the sharing of transfer factors between people suffering from serious conditions such as the HIV virus or hepatitis is a high risk action, and fifty years later, in 1999, bovine colostrum was discussed at a transfer factor conference in Mexico. Bovine colostrum contains large quantities of transfer factors such as IgG type immunoglobulins and hydrogen peroxide. The latter is commonly produced by our body cells to fight off invading pathogens, and immunoglobulins are very effective in fighting some diseases that can be fatal to AIDs patients. Take Cryptosporidium parvum, for instance. This microorganism causes a form of diarrhea that AIDs patients have no defense against but that colostrum can be particularly effective against, and it is also effective against rotavirus that is the main cause of diarrhea in young children.

Before discussing this further, let’s go back a step and examine how bovine milk came to be included in the equation. At one time it was believed that a baby received its immunity from the mother while in the womb and that this was extended via the mother’s milk. However, it was discovered that the milk contained no antibodies as such, only the colostrum, and these antibodies had somehow been transferred to the baby.

This was explained by the concept of the transfer factor. It is not the antibodies that are being transferred from mother to child, but the transfer factor. This modulates the immune system of the recipient and teaches it how to create antibodies against the specific antigens that the donor’s antibodies protect against and to inform the recipient’s immune system when these antigens are present.

The next step was to test the theory that the transfer factor should be able to be passed between species, and the cow was the obvious initial choice since not only are cattle exposed to many of the same antigens as humans, but we already use cow’s milk as a food source – particularly for babies and children. It worked! It was found that when humans were fed cow’s colostrum the specific antibodies were later found in the blood of the person given the treatment.

The next step was to determine the form in which this substance could be used, and injections of various types were tried without success. It was established that the only means of administering colostrum was by drinking it, or supplying it in capsule form. It can be drunk fresh or freeze dried to kill of living organisms and then fats and sugars removed and the resultant dried product encapsulated. It is even possible to remove all large molecules, antibodies, proteins, etc, and still retain the transfer factor. It is absorbed by the gut, and the resultant message passed to the recipient.

It is important to understand that it is not the immunoglobulins from the cow that are passed on, because these are species specific, and are in fact the source of most cow’s milk allergies. There is no transfer of antibodies or any other specific parts of the immune system. What are passed on are the messengers, particularly the transfer factors that are not species specific. A cow’s transfer factors would work just as well in a cat as in humans, only cats don’t get the same diseases as cows and people.

The types of disease that colostrum can help to protect us from include viral and bacterial diseases, fungal diseases and parasites, and neurological and autoimmune diseases. If you have cancer, colostrum can help significantly since cancer and immune deficiency are related. Cancer cells are being formed all the time in your body, but your immune system generally disposes of them. However, if it fails to do this, then the cells can proliferate and lead to cancer as we know it. Colostrum can help your body to prevent cancer occurring, and if you have it, can help to reduce its spread.

Freelance journalist Sam Wainaina studied the effects of Ebola virus in Uganda after the 2002 outbreak, and concluded that had transfer factors been available during the outbreak to transfer immunity it might perhaps have been contained sooner than it was, and saved many, many lives. Although transfer factors have been known of for 60 years, there is still a lot to be done in their application and studies on colostrum could help to accelerate this. Transfer factors alert immune cells to danger, train the system to generate the right type of immunoglobulins and boost NK cell activity to defeat the invaders. They can also moderate an over-active immune system that can be as much a danger to the body as an invading pathogen.

Colostrum can also be used to burn fat and create muscle tissue, and is popular with bodybuilders but it is for its healing and immunity-boosting properties that it is most used. Biotechnology companies are now boosting the colostrum’s transfer factors by injecting cows with vaccines that create pathogens. Known as Ultra Colostrum this is an advance on the natural material.

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Date: May 07, 2008 03:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B Vitamin Supplements

The fact that B vitamins have had to be coenzymated before they can be used by your body has been known for some time, but it is only over the past few years that they have been made commercially available in that form. Before we discuss the B vitamins in their coenzyme form it might be appropriate to discuss what coenzymes are and how they differ from ordinary enzymes.

An enzyme is like an organic catalyst: it takes part in biochemical reactions by allowing such reactions to take place, but itself remaining unchanged. All enzymes are proteins formed in your body from amino acids and other protein material. A coenzyme, on the other hand, is somewhat like an enzyme for the enzymes, in that it is needed for the enzyme to do its job. Without a coenzyme, many enzymes could not promote the biochemical reaction it is responsible for.

The B vitamins are all water soluble, which means that they are readily excreted and it is not impossible that if you take a B vitamin supplement, the whole lot will be immediately excreted in your urine if not used by your body. Whether they are or not it is a fact that your body can quickly become depleted of the B vitamin group, especially if you drink a lot. Alcoholics in particular are frequently vitamin B deficient. Although the liver can store unused vitamin B, they are only very small quantities and insufficient to prevent a deficiency.

A deficiency in the B vitamins can cause a wide range of unpleasant conditions that are rapidly remedied with supplements. Pellagra is due largely to a deficiency in Vitamin B3, and causes hair loss, horrible skin lesions and many other side effects that you don’t want to know about. Vitamin B12 deficiency can cause loss of memory, and is common in alcoholics and some vegetarians (vitamin B12 is animal derived). Other symptoms of a general B vitamin deficiency include exhaustion, heart palpitations, fibrillation, anxiety, restlessness, attention deficit disorder and many, many more.

It is not pleasant so you make sure that take enough vitamin B in your diet: dietary sources are far superior to pills although supplements will help you get over the symptoms of the deficiency until your diet takes over. Supplementation is also a good way to maintain a regular supply of vitamin B complex irrespective of your diet. The effects of a deficiency are so bad that a regular supplement is well worth taking.

However, back to coenzymes and why they are needed for the metabolism of B vitamins in your body. Most B vitamins are, in fact, coenzymes themselves. Keep in mind that the definition of a vitamin is an organic substance that is essential for the normal health of your body. If you lack even one vitamin, your health with suffer and eventually you will be likely to die. That describes all of the B vitamins perfectly, and they also just happen to be coenzymes. This is not coincidence, of course, and their biochemistry must have been recognized before the concept of coenzymes was formulated.

The B vitamins proper consist of eight distinct proteins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), B9 (folic acid), B12 (cyanocobalamin), and biotin and pantothenic acid. They are all essential components in human and animal metabolism, and most are also coenzymes.

Every cell in your body depends on B vitamins for its existence, which is why pregnant women should include a good supply of them in their diet, especially folic acid (B9). They are essential for the cellular development of the fetus. Folic acid is necessary for the synthesis of nucleic acids that allow cell growth and the production of red blood cells. However, not one can be placed in importance above any other since they are all essential.

With respect to the coenzyme factor, the vitamin B coenzymes are responsible for many of the biochemical reactions upon which life depends. Coenzyme B-12 for example is essential for two types of reaction that it catalyzes, one being a hydrogen atom exchange with alcohol and amine functional groups, the other being connected with methyl group transfer between molecules.

In humans, the first of these is responsible for an essential step that results in energy being metabolized from fats and proteins in the mitochondria and the second for DNA production in cells that is indirectly responsible for growth. Each of these is why a vitamin B-12 deficiency leads to excessive fatigue and also a lack of fetal growth (although folic acid can make up for the latter deficiency).

Thiamine (Vitamin B1) is a coenzyme for the metabolism of carbohydrates to energy. In the body it is present in the form of thiamine diphosphate, a coenzyme that assists in the decarboxylation of pyruvate as part of the citric acid cycle, otherwise known as the Krebs Cycle, that takes place in the mitochondria and is responsible for the generation of energy through aerobic respiration.

Another coenzyme that is involved in the Krebs Cycle is formed in the body from Vitamin B3, or niacin. This coenzyme, nicotinamine adenine dinucleotide, has a redox potential and can store energy for use later on. Vitamin B5 can be converted in the body to Coenzyme A that not only breaks proteins down into individual amino acids, but also takes part in the first part of the Krebs Cycle. There is a common pattern emerging here where the B vitamins have an important part to play in the generation of energy from fats and carbohydrates.

Similarly, Vitamin B6 is present in the body as the coenzyme Pyridoxal 5'-phosphate that helps to break down the body’s emergency energy store, glycogen, into energy when needed.

In these ways, and more, the coenzymes created in the body from the B vitamins help many of the reactions of life to take place, and without these coenzymes life could not exist. Hence the importance of the B vitamins themselves, and any deficiency could be disastrous to the metabolic processes that generate energy and keep you alive. It is not just the energy needed for exercise and normal human activity that will be compromised, but also that which keeps the heart beating and your diaphragm moving to allow you to breath.

Without a doubt, a Vitamin B supplement is one of the most valuable of all the vitamin supplements, and they are available in many forms. You might also find some of the B vitamins in their coenzyme form, though some of them may be unstable. However, whatever form they are taken in, Vitamin B complex should be one of the first on your vitamin supplement shopping list.

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Date: April 10, 2008 01:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Prevention and Treatment or Prostate Cancer

Last week I shared with you the controversy surrounding the use of PSA screening to determine the status of the prostate. There are many doctors who do not believe that using PSA is accurate enough to rely on for determining whether or not a high PSA indicates prostate cancer. Many men, who have a high PSA, after more detailed examination, did not have cancer and men with a low PSA did have cancer. Some physicians do not believe that the current methods of diagnosing prostate disorders are saving lives. Also, there is a group of physicians nationwide that strongly believe the best treatment is no treatment but rather a “watch and wait” approach. Prostate cancer usually is slow growing and more than 70% of men who develop it are over 65.

The older a man is, the more likely he is to die of some other condition before his prostate cancer becomes a real threat. To reiterate, the American Cancer Society states, “at this time watchful waiting is a reasonable option for some men with slow growing cancers because it is not known whether active treatment such as surgery, radiation therapy or hormone therapy prolongs survival”. So what action can be taken? While prostate enlargement (BPH) is not related to prostate cancer, it can elevate PSA scores and can cause symptoms in 50% of men by age 80 and nearly all will show signs of BPH by age 85.

If you have early symptoms of BPH such as frequency of urination, a burning feeling after urination and the caliber of stream that isn’t what it used to be, getting up several times through the night and low back pain, taking a good prostate support formula will be your best treatment and prevention. Most men will notice a remarkable improvement within a few weeks. A good prostate support formula will provide relief for 80-90% of all men from these annoying symptoms.

But what about prostate cancer?

The best cure for prostate cancer is prevention. I’ll give you a complete supplement program for prevention but first what about PSA testing? “I don’t believe in screening for something when it’s too late. By the time cancer develops a positive mammography or a true high PSA are likely too late, or if fortunate, that particular cancer will not be a problem. It makes far more sense to prevent the problem in the first place. And there is clear data, prevention is possible”. Dr. Robert J. Rowen, MD, Second Opinion, Soundview Communications. My recommendation, based on research of several scientific studies, includes various nutritional supplements and herbal extracts.

Following are several very important studies that all men should be aware of. In 1966 Dr. Larry Clark of the University of Arizona published startling data suggesting that prostate cancer could be reduced by as much as an amazing 60% by supplemental yeast derived selenium, 200 mcg per day. Selenium is a powerful antioxidant and participates in key and crucial detoxification and free radical scavenging enzymes (80-90% of all disease is caused by free radical damage and inflammation).

Selenium is one of a number of antioxidants to prevent this free radical damage; In 1999 a New Zealand study published in the British Journal of Cancer documented a 40% lower incident of prostate cancer in men with the highest levels of omega-3 fatty acids EPA and DHA in their blood. These findings have been confirmed in other omega-3 fatty acid studies. Conversely, another published report documents a high level of omega-6 to omega-3 fatty acids in invasive prostate tissue samples. Taken together with recent reports on high levels of omega-6 fatty acids (soy, sunflower, safflower, peanut, corn and most vegetable oils) linked to breast cancer, a common thread emerges. The American diet is overwhelmed with omega-6 oils.

Excessive use of omega-6 fatty acids are cancer causing and also cause inflammation. Trans fatty acids from hydrogenated oils seriously add to the problem. There are other nutrients that have shown to reduce prostate-cancer risk. Vitamin E and lycopene have also shown to prevent prostate cancer. Lycopene is commonly found in tomatoes, especially cooked tomatoes. If you like spaghetti sauce or salsa, this is a great way to fight prostate cancer. While vitamin E, selenium, lycopene and omega-3 fatty acids are all great prostate supporting nutrients, through research I found a much more powerful combination of food grade molecules that can prevent and treat cancer.

Extensive research in the last few years has revealed that regular consumption of certain fruits and vegetables can reduce the risk of prostate cancer. Fruits and vegetables having the highest degree of prostate cancer protection are the following: grapes (resveratrol), garlic, tomatoes, hot peppers, turmeric (curcumin), ginger, berries, milk thistle, cloves and fennel. These foods are protective because they are extremely active and excellent antioxidants. My favorite is turmeric (curcumin) because not only is it an antioxidant, it is also an anti-inflammatory agent. When it has this dual effect it is many times more potent than other types of food. In the United States there is 30 times more prostate cancers diagnosed than there are in India where turmeric is consumed liberally in most of the Indian dishes. Cancer does not begin shortly before it’s diagnosed.

The origin of cancer may be years or decades in the process before it is even diagnosed as such. It is a multi-step process that goes through various phases such as cellular damage and transformation and culminates in the acquisition of invasive potential angiogenic properties and establishment of metastatic lesions. This process, and probably rightly so for all cancers, can be activated by any one of the various environmental carcinogens (cancer causing); all forms of tobacco products, industrial emissions, gasoline vapors, inflammatory agents, food coloring and preservatives, excessive UV rays, alcohol, hair dyes, cleaning products and drugs.

The multi-step process of these cancer causing compounds progress in three stages; tumor initiation, promotion and progression phases. A powerful antioxidant/anti-inflammatory can prevent most if not all of the damaging effects when taken on a daily basis. Several population based studies indicate that people in Southeast Asian countries have a much lower risk of acquiring colon, gastrointestinal, prostate, breast and other cancers when compared to their western counterparts. It is very likely that constituents of their diet such as garlic, ginger, turmeric, onion, tomatoes, cruciferous vegetables, chili’s and green tea play an important role in their ability to avoid these cancers.

These foods, or key active extracts from these foods, are known to block the NF-kB activation process. Also, several phytochemicals such as curcumin, resveratrol and green tea catechins have been shown to suppress AP-1. Several chemopreventative phytochemicals including curcumin, resveratrol and green tea have been recently shown to be powerful inhibitors of several growth factor receptors including EGFR. Curcumin also possesses the capacity to inhibit the activation of the EGF-Receptor indicating that it has the potential to break the autocrine loops that are established in several advanced cancers.

Studies also suggest that curcumin, resveratrol and green tea can actually be used as safe, non-toxic treatments in drug resistant cancers. These natural phytochemicals (food grade) can help fight certain cancers thereby requiring a smaller dose of drug chemotherapy. They also can protect the body from the damages of drug chemotherapy and radiation. “This mini review presents evidence that chemopreventative agents, curcumin, green tea and resveratrol, can be used not just to prevent cancer but also to treat cancer. Because of their pharmacological safety, most chemopreventative agents can be used in combination with drug chemotherapeutic agents to enhance the affect at lower doses and thus minimize chemotherapy- induced toxicity. Because cancer is primarily a disease of old age, less toxic therapy is a major priority. This review reveals that molecular targets of chemopreventative agents are similar to those currently being used for the treatment of cancer. Tumor cells use multiple cell survival pathways to prevail and thus agents that can suppress multiple pathways have great potential for the treatment of cancer”1,2. Curcumin, resveratrol and green tea were as effective in preventing and treating certain cancers based on lab and animal studies. There have been approximately 20 human positive studies but much more needs to be done.

From the research that I have done, I am convinced sufficiently enough to take many of these compounds as a preventative of cancer. These compounds are completely safe and non-toxic even in high doses. What does one have to lose? Why not take the positive preventative measure? –Compliments of Terry Naturally

Ref: 1. Role of chemopreventaive agents in cancer therapy. Comprehensive Cancer Center Our Lady of Mercy Medical Center, New York Medical College, Bronx New York

2. Cytokine Research Section, Department of Bioimmuno Therapy, University of Texas, M.D Anderson Cancer Center, Houston Texas

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Date: February 03, 2008 02:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acai: The Super Antioxidant From Brazil

Acai is an Amazonian palm tree, and possesses small purple fruits that the Amazonian natives of Brazil have used since time immemorial as food and as a remedy for certain health conditions that are now known to be associated with the activity on free radicals on body cells.

The active constituents of acai are powerful polyphenols and anthocyanin antioxidants that protect your body cells from oxidation by free radicals. In fact the plant has been referred to as ‘the super antioxidant from Brazil’ by many medical writers who have recognized its right to be termed as such. To understand that, you first have to understand what an antioxidant is and how it works. The chemical names of the active substances it contains will be meaningless without that background knowledge.

Oxidation occurs in your body even before you are born. What is does in general terms is to destroy your body cells, and the more it progresses the more your body is prone to cancers and cardiovascular diseases, and the more visible becomes the aging process. Chemically, oxidation is the loss of one or more electrons by an atom or molecule. Oxidation within your body is highly associated with what are known as free radicals. To explain these we have to consider the chemistry of electron pairs and free radicals, though this is not too technical so read on.

Normally electrons exist in pairs of opposite spin: in simple terms each pair makes up a single negative charge. Take hydrogen: its atomic structure contains one proton and one electron. However, the hydrogen atom cannot exist by itself since the most stable configuration is that electrons exist in pairs with a net zero spin, so the hydrogen molecule consists of two hydrogen atoms with their own protons sharing an electron pair. This is true of all covalently bonded molecules.

However, certain influences, such as pollution through tobacco smoke, pesticides, engine exhausts and the excess UV radiation of sunlight can cause a molecule to lose an electron. This creates what is known as a free radical: a molecule without an electrical charge but with an unpaired electron. Since the most stable configuration for it is to have a paired electron, the molecule will steal an electron from the most suitable candidate it finds.

In practise this will be a body cell, and the cell that loses the electron gets destroyed causing aging of the skin and many other undesirable effects, including cancers. This stealing of an electron is chemically referred to as oxidation. Antioxidants prevent this occurring to your body cells by being reactive themselves and preferentially mopping up these free electrons.

Polyphenols and anthocyanins are powerful antioxidants, and that is why the people of the Amazon rainforests have used acai not only as a food, but also for their health. It is only relatively recently that, as with many of the ancient health remedies, the scientific basis behind its use has been proved. The early Brazilian natives may not have understood biochemistry or what free radicals were, but they sure knew what was good for them.

As with many other foodstuffs containing powerful antioxidants, it is likely that it was the highly colored berries that first attracted them. That does not suggest that all brightly colored foods are good for you, but the brightly colored pigments and dyestuffs contained within them also tend to act as antioxidants due the same electron configuration that provides them with their color. Many of these chemicals are also use as food dyes, and have been used so since before their chemistry and antioxidant effects were known. The color comes from the same electron activity that makes them destroy free radicals. That is why most highly colored foods contain significant quantities of phytochemicals.

The deep purple color of the acai fruit led chemists to determine its content of polyphenols, such as anthocyanins, that are common in other highly colored foods such blueberries, peppers and aubergines. High concentrations of anthocyanins such as cyandin-3-glucoside and the rutinoside analogue were found, together with flavonoids such as orientin, deoxyhexose and scoparin. A total of twelve flavonoids were discovered that explains the highly antioxidant properties of the fruits. Laboratory and other tests have indicated that over 80% of the antioxidant effect of acai is due to polyphenols other than the anthocyanins. It is likely that these are the twelve flavonoids identified to date and any others that have still to be detected.

However, it is not only for its antioxidant properties that acai is such a healthy fruit, since it contains many other nutritional components. It contains fatty acids, including linoleic acid, an omega-6 fatty acid and also beta-sitosterol that are believed to reduce the level of LDL cholesterol in the blood. The fruit also contains a high level of amino acids, essential for the synthesis of proteins and DNA.

So what exactly does this mean for you in real terms? Antioxidants can do different things for different people, and the acai berry is said to have more than thirty times the antioxidant power of red wine. When you consider that many doctors believe one glass of red wine to provide sufficient antioxidant for the average person, you are getting a very high dose with acai berries, so what does it do for you?

Due its effect in destroying the free radicals caused by pollution, acai and similar powerful sources of antioxidants are becoming increasingly important to our diets. What was a sufficient antioxidant intake even twenty years ago is not longer sufficient. Acai can help to combat early aging by reducing the rate at which your body cells are destroyed by free radicals. It also reduces the risk of cardiovascular disease, and the associated high risk of strokes or heart attacks.

Acai juice itself has an unusually high fiber content, and helps maintain the health of your digestive system. An associated benefit of this is that you are less liable to contract colon cancer than if you did not consume it. Due to a reduction in the rate of destruction of body cells, including brain cells, elderly people benefit through maintenance of their brain function, and a lower likelihood of degenerating cognitive ability. It helps you to maintain concentration and memory, and can also reduce the risk of you getting cataracts.

Antioxidants are also known to help maintain the immune system, and act as anti-inflammatories, and it is believed that acai juice can help to reduce the symptoms of arthritis. If you use acai berries as part of a daily diet, you should receive the benefits that it provides, although a more measured dosage in the form of a supplement will enable you to control your intake of acai, and if one thing is certain it is that you will be far healthy with a regular dose of the superantioxidant from Brazil than without.

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Date: January 18, 2008 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Give Your Health A Boost With Silica Hydride A Powerful Antioxidant

Hydride ions are strong proton acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.

A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.

Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.

This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.

The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.

This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.

An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.

Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.

In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.

Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.

Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.

Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.

If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.

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Date: January 15, 2008 05:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Which Form Of Calcium Is Best For You?

There is no warning signal that lets you know if you have a calcium deficiency. Actually, a calcium deficiency is usually undetectable until damage that is irreversible has already occurred. A calcium deficiency is extremely hard to detect because the calcium level in the blood may seem to be normal, even if extreme cases of deficiency are actually occurring. This is because the body has a calcium bank, which can be found in teeth and bones. Calcium is needed in order to control muscular contractions such as the heart, blood-clotting, transmission of nerve impulses, and other requirements which take priority.

You may not know for sure whether you have calcium deficiency until you experience loose teeth, receding gums, or a bone fracture. At this point you will realize how brittle and chalky your bones have become. There is no known cure for osteoporosis, and it seems to be affecting people at younger ages more and more. The progression towards this illness takes years, but it is going on unnoticed in a great percentage of our population right as we speak.

There are many reasons why calcium deficiency is so widespread. First, calcium is not easily absorbed, as no more than 10-20% of what is found in foods is actually consumed and metabolized. This is because a meal that is high in fats can form insoluble calcium soaps which cause calcium to pass through the system without being absorbed. Also, the calcium in certain vegetables can actually be inhibited from releasing by oxalates that are found naturally in foods such as rhubarb, kale, spinach, broccoli, grains, and cereals.

Furthermore, vitamins A and D must be present in the body in order for absorption to occur. Additionally, calcium requires an acid environment for absorption, which is a huge problem for older people who have less production of digestive acids. More so, amino acids are needed for the formation of calcium-amino acid complexes and magnesium and phosphorus must be present in a precise ratio’s. Without all of these factors, you can lose a lot of the benefit, no matter how much calcium you are taking in.

A great variety of calcium supplements can be found in your health food store. These supplements can range from a simple calcium carbonate to bone meal, dicalcium phosphate, dolomite, calcium lactate, calcium gluconate, and many others. Although they all contain calcium, they vary in the amount of actual calcium content from 40% in calcium carbonate to 9% in calcium gluconate. Calcium carbonate has the highest percentage calcium per gram, but it acts as an antacid which makes this supplement somewhat useless since calcium can only be absorbed in an acid environment.

Acid breaks down the bonds between the calcium element and its bonding partner like carbonate or amino acid chelate. Calcium Carbonate has a carbon bond the strongest bond of its kind; this makes it extremely unwise for those people who are older or suffer from a digestive acid deficiency. Calcium carbonate that is derived from oyster shells is no different from any other form. However, oyster shells carry an additional risk of being contaminated with naturally occurring heavy metals found in the oyster bed environment. Calcium phosphate is probably the best source of calcium, since the principle calcium in the body is actually calcium hydrogen phosphate which is easy to digest.

Whether you choose calcium carbonate or calcium citrate, ask your local health food store which calcium is best for you depending on your age and whether you have a digestion disorder or not. With poor diets and lack of exercise, calcium supplementation is a must for most people. Have you had your calcium today?

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Date: December 07, 2007 11:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: L-Glutathione Can Eliminate Toxins in the Liver

L-glutathione is the reduced form of glutathione, and is a tripeptide synthesized in the animal and plant tissues from glycine, cysteine and glutamate. Commonly known as GSH, it contains thiol groups that are maintained in a reduced state, and is a very powerful antioxidant, considered to be the key antioxidant and protective substance in the body.

Glutathione can reduce any disulfide groups in the cytoplasm within the body of the cell, and ensures that the cytoplasm is a strongly reducing medium protecting against oxidation. It has a synergistic effect with other antioxidants to protect the body against free radicals and oxidizing agents that cause so much damage to the body through what is commonly referred to as ‘oxidative stress’. However, there is more to it than that and it attaches itself to toxic chemicals and drugs in the liver and renders them into a state suitable for elimination from the body.

These toxic materials include poisonous pesticides, hydrogen sulfide, carbon monoxide, heavy metals such as mercury, cadmium and chromium and many other substances that we come into contact with due to present day pollution of our atmosphere and foodstuffs. Glutathione can also help protect the body from the effects of chemotherapy and evidence is suggesting possible links with the control of some cancers, diabetes, atherosclerosis and many other degenerative conditions caused by free radical attack and the effects of pollutants.

The way that GSH acts in the cells is that the redox state of the glutathione-glutathione disulfide couple is critical to the health of the intercellular and intracellular fluid. GSH in the reduced state of glutathione reacts with an oxidative agent such as hydrogen peroxide to form the oxidized form, glutathione disulfide and water. It hence mops up oxidizers such as peroxides and free radicals within the cytoplasm of the body’s cells, and also in between the cells. The disulfide is then converted back to GSH by the combined action of the enzyme glutathione reductase and NADPH (the reducing agent nicotinamide adenine dinucleotide phosphate).

The cycle then repeats so that two molecules of glutathione continue to reduce damaging oxidizing agents without themselves being consumed. In so doing, the NADPH becomes oxidized. A continuous supply of NADPH is needed to allow GSH to undergo these biochemical reactions, and up to 10% of our blood glucose is used by the pentose phosphate pathway by which NADPH is synthesized.

Since this cycle consumes no glutathione, it would appear that a supplement is unnecessary. However, this is not the case since the molecule takes part in other reactions in the body, particularly in the elimination of toxic heavy metals from the body. Mercury is highly reactive with the thiol that GSH is, and so will bind to form a stable Hg-sulfydryl bond in the liver. This mercury-glutathione chelate is unable to bind to other proteins or gain access to the body cells, and is eventually harmlessly secreted. The same is true of many other heavy metals that are reactive with thiol’s.

In this way the body is protected from the harmful effects of these heavy metals. However, it results in the loss of the glutathione, and the pollution of modern day living can take a heavy toll of the GSH content of our bodies. For this reason a glutathione supplement is recommended, especially for city dwellers that may be exposed to more heavy metals than those residing in rural areas.

However, the form in which this supplement is taken is very important, because the human digestive tract contains a significant amount of gamma-glutamyltranspeptidase. That is an enzyme which apparently destroys glutathione before it can be absorbed. However, it can be absorbed directly into the bloodstream by dissolving the pill between the teeth and inner cheek. It has also been suggestion that the supplement could be administered by injection.

Others have suggested that rather than administer a supplement, individuals could take other supplements that contain the materials needed to stimulate the formation of GSH. Substances such as vitamin C, selenium (important in GSH biochemistry), methionine, alpha-lipoic acid and glutamine could all help to increase the body’s production of glutathione. A supplement of the constituent parts of cysteine, glycine and glutamic acid should also help. The dosage ranges recommended vary widely from 50mg to 500mg daily, and the effects of supplementation are not yet well know.

Some specific conditions that this wonder antioxidant is useful in treating include liver disease such as hepatitis, cirrhosis and so on. Patients suffering from these diseases show a massive reduction in their GSH content and prior GSH treatment appeared to offer a significant degree of protection in controlled clinical investigations. Patients suffering from chronic hepatitis C have been found to be associated with reduced GSH levels, particularly if also HIV positive.

Similar deficiencies have been noted in some lung conditions such as asthma and other pulmonary conditions. In such cases it has been demonstrated that administration of GSH supplements sufficient to restore normal levels of the substance improved the patients’ conditions by a significant amount. Its effect on atherosclerosis appears to be significant since a decreased level of GSH peroxidase has been recorded in such patients in addition to an increase in lipid peroxides, indicating that oxidation of the arterial wall had been occurring.

Anti-viral therapies that rely on GSH biochemistry for their action have been found to be less effective in those with low GSH levels, and other studies have confirmed that supplementing with GSH improves the response to interferon treatment. These results indicate the activity of oxidizing agents and free radicals in liver conditions, and in fact this has been demonstrated by tests carried out in New York and Philadelphia in the 1990s.

This suggests that the liver is prone to damage by oxidative stress, and that GSH levels may be able to be used as an indication of potential liver disease. What is evident is that a strong case can be made for glutathione supplementation as protection against potential liver, pulmonary and cardiovascular diseases, especially by those exposed to specific polluting agents such as primary or secondary tobacco smoke, auto and diesel fumes and chemicals and pesticides.

L-glutathione is useful, not only for the elimination of toxins in the liver, but also in protecting this large and vital organ from the oxidative stress that modern living brings. L-Glutathione and its precursors are sold over the counter at your local or internet health food store.

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Date: November 13, 2007 10:22 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Healing Power Of Borage Oil’s GLA

Borage is otherwise called the starflower, and the borage oil extracted from its seeds is very rich in GLA, gamma linolenic acid, a polyunsaturated fatty acid also obtainable from evening primrose oil. Borage, however, is richer in GLA, and is therefore a more economical source that the evening primrose.

A shrub, frequently seen in gardens, borage has historically been used as a salad food, and also in soups, and borage honey is prized in many quarters. Now, however, its main use is for the GLA extracted from the seed, which provides a higher yield of GLA than any other source. Borage seed oil contains up to 25% GLA, compared to the 17% from blackcurrant oil and 9% from evening primrose oil.

The importance of GLA to the body’s biochemistry is inestimable, and cannot be overstated. It is not so much the GLA that is so important, but the prostaglandin to which it is converted in the body. Prostaglandin E1 is a hormone-like substance that plays a part in many of the biochemical and metabolic processes of the body. Examples include the control of the immune system and inflammatory response, some kidney functions, and the tone of the arterial muscles, so important in the health of the cardiovascular system.

A good fatty acid metabolism benefits some very important aspects of our health such as maintaining a good blood pressure, low cholesterol levels, preventing inflammatory and immune system conditions such as arthritis, allergies and some skin diseases such as eczema and psoriasis, and also improving the strength of the keratin-dependent tissues such as our nails and hair.

A deficiency in essential fatty acids also seems to stimulate the overproduction of a hormone in women called prolactin that can lead to the severe mood changes commonly referred to as pre-menstrual syndrome, or PMS. GLA appears to have a beneficial effect in the treatment of PMS, and some other conditions such as breast discomfort.

Gamma linolenic acid is created in the body from linoleic acid, of which there is a plentiful supply in margarine, vegetable oils and many processed foods, but there is a problem. Fatty acid molecules come in different isomeric forms, in which although the chemical is the same, the geometry or ‘stereochemistry’ is different. The healthy form is the ‘cis’ formation, and the other is the ‘trans’ stereoisomer. The trans fatty acids are formed by hydrogenation of oils to make them semi-solid, and more suitable for spreading. This hydrogenation process causes an irreversible change in the geometry of the fatty acid that can block the conversion of linoleic acid to GLA in the body.

Hence, although most of the western population has more than sufficient linoleic acid in their diets, many who eat an excess of trans fats have a deficiency of GLA. Some B vitamin deficiencies and a deficiency in certain minerals exacerbate this situation, and a gamma linolenic acid supplement is needed. Additional to this, the enzyme responsible for the conversion, delta-6-desaturase (D6D) can be affected by many modern environmental factors such as smoking, stress, alcohol, excessive animal fat consumption and even excessive linoleic acid consumption. The solution to all of this is GLA which does not require any enzymes for its creation, and supplemental GLA from any source can immediately take part in the biochemical pathway to the creation of the prostaglandin eicosanoids.

GLA provides the means and the resultant prostaglandins carry out the job of regulating the hormonal activity within human biochemistry. Prostaglandins help to regulate the function of many of the cells in the body, such as the smooth muscle cells of the arteries and veins that cause constriction or dilation, and on the stickiness of blood platelets causing their aggregation. They are important in the regulation of such functions as blood clotting, fluid balance and the production and balance of hormones. The anti-inflammatory properties of prostaglandin E1 are very important to the way that the body reacts to breaches by foreign invaders, and it is also thought to act to thin the blood and cause dilation of blood vessels, hence its effect in lowering the blood pressure.

So what does this mean to you, apart from the effects of the fatty acid on PMS? Borage oil can be used to treat a large number of different symptoms associated with a shortage of GLA and prostaglandin E1, and here are a few of the conditions for which a GLA supplement has been found beneficial.

A deficiency in GLA and other essential fatty acids can lead to loss of bone mass and subsequent osteoporosis and it is thought that fatty acids help the absorption of calcium by the digestive system, and to increase its deposit in bones. It can be used to increase bone mass and density and therefore strengthen the bones of those affected by osteoporosis. This is partially due to the hormone regulatory effect GLA has on the body.

Allergies appear to be very personal responses by the immune system to specific substances, and while borage oil has proved beneficial in a few allergies, and prostaglandins are known to regulate the activity of the immune response, the effectiveness of GLA treatment for allergies has been mixed. There is evidence that it can affect some cases, but not most.

GLA from borage oil can reduce the swelling and pain of rheumatoid arthritis, and helps to ease morning stiffness. Its effectiveness seems mixed, and you should try it for two or three months to determine if it helps you personally. Be careful, however, since some believe that it might react with some of the non-steroidal anti-inflammatory drugs (NSAID) used to treat this condition. Ibuprofen is one, so check with your physician before trying it.

If you suffer from high blood pressure, borage oil used in conjunction with Omega-3 fish oils might lower it, though more research is needed. There is a belief that the GLA is not the active agent here since Omega-3 oils are known to help to reduce hypertension, though the effect of prostaglandins on the factors that can reduce blood pressure is inarguable.

The healing power of borage oil should not be underestimated, and it has been used for centuries in folk medicine to treat many conditions, especially those that science has found to be caused by the immune system and the inflammatory response. Borage oil can be found at any Health Food Store.

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Date: November 10, 2007 02:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Maca a Magic Root?

Maca is packed with nutrients; loaded with vitamins and minerals to help fuel brain function and ease hormone irregularities as well as nourish the body.

Maca contains:
1. vitamins: B1, B2, and vitamin C
2. Alkaloids: contains 4 novel alkaloids: Macaina 1, 2, 3, 4.
3. Bismuth: Aids in combating bacteria that causes gastritis.
4. Calcium: supports strong bones and teeth.
5. Copper: supporting hemoglobin production
6. Fatty acids: contains 20 fatty acids 7. Silicon: helps hair, skin, nails, and connective tissue.
8. Iron: supports hemoglobin also.
9. Magnesium: essential for protein synthesis, and activities of muscles and nerves.
10. Manganese: essential mineral
11. Phosphorus: regulates the transmission of neuromuscular chemicals and electrical stimuli. Important for the hemostasis of calcium, and the reactions of lipids, carbohydrates, and proteins. The body’s chemical energy is stored in phosphate compounds.
12. Potassium: participates in the regulation of osmotic pressure; its activity is carried out inside the cells.
13. sodium: when working with potassium helps reduce arterial pressure and hypertension.
14. Tannins: useful in the treatment of diarrhea. Combined with other medicines, they have the utility of treating inflammatory processes like ulcers and sores.
15. Zinc: a cofactor of dehydrogenises and carbonic anhydrite; its lack can cause skin rashes, taste disturbances, and mental lethargy.
16. Carbohydrates: quality carbs.
17. Fructose: Natural fruit sweetener
18. Micronutrients: minerals which help with the production of antibodies.
19. Proteins: rich in bio-available maca protein average of 11% grams in dry root.
20. Starch: chemical compounds that influence the nutrition and health of consumers.
21. Fiber: loaded with cellulose and lignin which stimulates intestinal operations.
22. Macronutrients: essential vitamins and minerals, nutritive properties to help convalescent people who are diagnosed with anemia.

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Date: October 21, 2007 07:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Staying Healthy Means Keeping Your Blood In The Proper PH

The blood should be electrolytically neutral, or very slightly alkaline. The proper pH for blood should be 7 or just above it, and many claim that it should be 7.35. In fact the truth is that your blood pH should be between 7.2 and 7.6. Outside these limits and you could have serious health problems, with your brain particularly being affected.

For those who have forgotten their school chemistry, pH is a measurement of the level of acidity or alkalinity of an aqueous solution. Anything over 7 is said to be alkaline, and below 7 is acidic. Where the pH has to be maintained at a certain level, a material called a buffer is used that counteracts the effects of other acids and alkalis to maintain the desired pH range. Buffers are very common in nature, as would be expected of life forms that depend upon water and aqueous solutions for their survival. Blood is an aqueous solution containing plasma, blood cells, nutrients and various other ingredients in both solution and dispersed solid form.

The human body possesses a very effective pH maintenance system that depends on various buffers, the kidneys and the lungs. Lets have a closer look at buffers and how they work. pH is, in fact, a measurement of the concentration of hydrogen ions (H+) in a solution. The way a buffer works is to absorb or release H+ ions to keep the hydrogen ion concentration at a specific level. If there are too many H+ ions present in the blood, and it becomes too acidic, then the buffer will mop up the excess. If there are too few, and the blood becomes too alkaline, then the buffer will release more hydrogen ions into the blood. In this way the pH is maintained at the limits mentioned above.

Buffers in the human body include some forms of protein, phosphates and also hemoglobin. However, if the pH variations are more than just occasional, the buffers have a limited capability, and a more permanent solution is needed. If the blood is continually becoming too acidic, the bicarbonate ion is used to clear them up. Just as bicarbonate of soda is used to clear up excess acidity in your stomach that causes indigestion, so it can be used to clear up excess acidity in the blood. But how do we get the bicarbonate into the blood?

When the lungs inhale oxygen, they then exhale carbon dioxide. The bicarbonate ion, also called the hydrogen carbonate ion, is formed in the blood by dissolved carbon dioxide. The faster we breathe the more carbon dioxide we exhale and the less is left in the blood to form bicarbonate. The slower we breathe, the more carbon dioxide is available in the blood for bicarbonate. Thus, when our blood acidity increases we breathe slower, and when it decreases we breathe faster since less carbon dioxide is needed in the blood to form bicarbonate to neutralize the acid.

The kidneys also help to regulate the pH of the blood, although the biochemistry involved is fairly complex, and will not be covered here. It is enough to state that the body has a number of routes by which it can control the pH of the blood.

Current thinking is that alkaline and acidic foods should be balanced in your diet in order to place less of a strain on the body’s pH control systems. Since the blood pH must be slightly alkaline, then it might make sense to eat a slightly alkaline diet. However, it is not the actual food that matters, but what happens when the food is digested. Hence, orange juice is classed as an alkaline food even though it is high in citric acid and itself has a low pH. The same is true of lemons. They taste very sour, yet the result after digestion is alkaline. It is the end result that counts. After all, the stomach acid is very strong and very highly acidic, and eating slightly alkaline foods is not going to alter that. The digestive juices have to be highly acidic to break down the organic matter.

It had been calculated that a mix of around d 75% alkaline and 25% acidic food is a good combination of the two types to provide approximately the desired blood pH. Among the common acidic foods are meat, fish, poultry, plums, grains, eggs, wine, cheese and offal. The alkaline foods are most fruits and vegetables, orange and lemon juice, melons, potatoes and chocolate. Hence, it is possible to eat beef and chicken, and have the odd glass of wine so long as we eat plenty of fresh fruit and vegetables. There is nothing at all unusual with that diet, and it underlines the importance of eating a healthy balanced diet. While more greens and whole foods are definitely healthier for you, you should not eat exclusively an alkaline diet.

If your blood pH is on the high side of the limit, then you can eat a bit more meat or fish, and if on the low side eat a more vegetarian style diet. It is important, however, that you eat healthily, irrespective of whether you are eating alkaline or acidic foods. Through history, the human race has adopted a more acidic diet than the ancient hunter gatherers. Grains are a relatively recent invention, introduced after the invention of stone tools to mill them, and dairy products are also relatively recent in terms of the whole of human history. Even the consumption of meat only began after mankind learned first how to trap and then developed tools to enable them to kill their prey.

Human biochemistry, then, has developed from a predominantly vegetarian diet. However, protein is still very important, and while protein intake is necessary, should comprise no more than 20% - 25% of your total food intake. The rest should comprise of mainly fruits and vegetables, with whole rather than refined or processes foods predominating. Sugar was not eaten in quantity until the industrial revolution.

Measuring the pH of your blood is easy to do. It is simply a matter of using pH paper strips and checking the color change with your blood. They are available at most pharmacies and health food stores. If your pH level varies from 7.4 or 7.5, then you should change your diet accordingly. Higher than this, then eat more acidic foods, and if lower you should eat more alkaline food. It is simple equation, and the changes you will have to make to your diet will be minimal. Some of these changes can be made by the use of supplements that are carefully balanced to maintain your blood in the proper pH.

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Date: April 19, 2007 04:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Complete Liver Cleanse

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Date: April 09, 2007 05:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EpiCore Benefits

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Date: March 26, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supplements good for reducing stress and boosting energy!

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Date: November 03, 2006 04:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Enjoy Some Nuts Every Day

Although high in fat, nuts contain oils that reduce the risk of coronary heart disease. Nuts also contain potentially cardio protective components including phytosterols, tocopherols and squalene. Walnuts, almonds, pecans, Brazil nuts and macadamia nuts were all found to be good sources of these compounds. Diets that included one or two servings of macadamia nuts a day have been shown in studies done in Brisbane Australia and Honolulu Hawaii to improve blood lipid profiles as effectively as low-fat, complex carbohydrate diets. Furthermore, scientists at the Harvard School of Public Health found that eating nuts and peanut butter reduced the risk of type II diabetes in women. The researchers suggest that nuts might replace refined grain products, and red or processed meats as a way to limit caloric intake.

The Lowly Goober Gets New Respect

Americans eat more peanuts and peanut butter than all other nuts combined. A Pennsylvania State University study of 13,000 men, women and children revealed that peanut eaters have higher intakes of several hard-to-get nutrients compared to those who did not consume peanuts. Peanut butter and peanut eaters have increased levels of vitamin A, vitamin E, folate, Calcium, magnesium, zinc, iron and phytonutrients resveratrol, beta sitosterol and p-courmaric acid. What’s more, peanut eaters also had leaner bodies than non peanut eaters. This study helps to dispel the myth that higher-fat foods automatically lead to weight gain.

The peanut Butter Diet evolved from studies such as this that showed the benefits of eating peanuts and peanut butter, particularly their high satiety factor. In one small study, ten health workers aged fifty-plus, consumed 1500 calories healthy and moderate fat (35%) diet that included two tablespoons of peanut butter eaten twice a day. The woman had at least one cardiovascular risk factor – high blood pressure, altered blood lipids or diabetes. Peanut butter was chosen because previous studies at Harvard/Brigham Women’s hospital had shown that over an eighteen-month period, three times as many women stuck with a diet that included peanut butter or peanuts, because of a hunger curbing effects.

Peanuts contain about 2 grams of fiber per tablespoon and when spread on two slices of whole-wheat bread, deliver six grams of fiber. Peanut butter makes some yummy sauces. The barbecued ribs a group of scientists and I prepared during a recent weekend at the Culinary Institute of America Greystone in California’s Napa Valley where the best I have ever eaten.

Tropical Oils

The term refers to coconut, palm kernel and palm oils. These oils contain a variety of fatty acids, but unlike olive, macadamia and peanut oils, which contain high levels of unsaturated fatty acids and are liquid at room temperature; tropical oils have high levels of saturated fats and are solid at room temperature. They are gaining popularity as food manufacturers push to replace hydrogenated oils that contain trans fats. The latest hoopla over coconut oil has been its inclusion in weight loss regimens. Two books featuring coconut products have hit bestseller lists. Moderate increase of tropical oils including coconut and palm appear to improve blood lipid profiles largely because of their high lauric acid content.

The health benefits of medium chain triglycerides (MCTs) such as caprylic and lauric have been known for some time. Lauric acid has been found to improve blood lipids and red palm oil is rich in antioxidants such as beta-carotene and tocotrienols, the vitamin E active constituent. However, there is concern among some experts that eating to many saturated fats, including the tropical oils used to make trans fat free margarine and shortening, can have deleterious effects on cardiovascular health.

In addition, there are differences in processing palm and palm kernel oils that make some choices unhealthy. According to Dr. Andrew Weil palm oil is a better choice than palm kernel oil because chemical solvents are needed to extract palm kernel oil while none are required to press the oil from palm fruit. Fractionation is used to process palm and palm kernel oil and eliminates many of their natural antioxidants, which makes them the least desirable of the tropical oils. It seems prudent to check ingredient labels for fractionated palm kernel oil and avoid it. Best of all, look for Now Organic Coconut Oil that has an impressive resume for boosting immunity. It also has a distinctive flavor to foods prepared with an eastern Indian theme.

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Date: October 17, 2006 03:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Which Calcium is Best?

Customers walking into a health food store today are faced with a vast array of calcium supplements. They might ask: which one should I pick? Which one is best? Not easy questions to answer. All calcium forms will accomplish the same task: providing your body with a nutrient that it needs to build healthy bones and teeth; however, which form of calcium has the features that you want in a calcium supplement? Looking at shelves of calcium products is kind of like shopping for a car; there are many makes and many models—some are basic and others are more sophisticated.

Fortunately, there are many forms of calcium to satisfy your needs. Like the car lot, a health food store offers many options; therefore, you have to select a calcium product that consumers will feel confident in taking regularly and that will provide the most benefit.

Some consumers have done research and will come armed with information. They have already made choices based on advertising, word-of-mouth or an article they have read. They already know the form of calcium they want, be it a “Ferrari” or a “Ford.” If the client doesn’t have a specific preference: asking these basic questions will help in the selection process:

1. Do you prefer tablets, capsules, softgels, liquid or powder?

• Tablets are for consumers who want high dosage in fewer pills.
• Capsules are flavorless and may be easier to swallow than tablets for some.
• Softgels have a slicker surface and may slide down the throat more easily for some.
• Liquids are easiest to swallow and are available in different flavors.
• Powders are flavorless, versatile and can be mixed with food or beverages.

2. Do you have high or low stomach acid?

• Should you use calcium that has buffering action or a calcium that does not further reduce your stomach acid.

3. Do you have absorption issues?

• Rapid transit time in the bowels may affect a person’s choice of calcium.

What is calcium?

Calcium (Ca) is one of the most important minerals found in our bones and teeth—99 percent of body calcium is found there. But the calcium molecule does not like to travel alone and, in its more basic state, it comes bounded to carbon (C), Oxygen (O), and/or hydrogen (H) molecules or in more complex form, it is bonded to organic or amino acids that act as stabilizing carriers. On most labels, the amount of calcium listed actually indicates the pure or elemental calcium because it is that amount of the calcium that is deemed important to our daily supplementation, not the complex of the materials with which it is bonded.

Where does calcium come from?

Other than the calcium found in bone, the only natural form of calcium found in nature is calcium carbonate, a calcium molecule bonded to one molecule of carbon and three molecules of oxygen (CaCO3). One of the most common minerals on the face of the earth, calcium carbonate is called calcite, aragonite or vaterite by geologists. In its geological form, it constitutes approximately four percent, by weight, or the earth’s crust.

Commercial sources of calcium carbonate used to make supplements are: limestone, dolomite, oyster cell, egg shell, coral and sea water (have you ever seen that white deposit left by hard water? That’s mostly calcium carbonate). Calcium carbonate is the starting material for all other forms of calcium supplements. From this starting material, calcium can be reduced to more concentrated forms, such as oxide or hydroxide or it can be chelated (bonded) to organic acids and amino acids to help support enhanced absorption.

Lets look more closely at the different forms of calcium that are available as supplements.

Calcium Oxide (CaO): this form is 71 percent elemental calcium and is also called “lime” commercially. This is one of the oldest and most inexpensive forms of calcium used in a variety of commercial applications and it is occasionally used in supplements where space and price are a factor. It sometimes can be found in inexpensive mass market calcium/mineral combinations or multivitamin/mineral products and in a unique algal calcium from Japan. Unfortunately, CaO is a strong alkali that may cause stomach distress, which is why it isn’t often used in health food supplements.

Calcium Hydroxide (CaHO): at 54 percent elemental calcium, it is the next highest source of elemental calcium and is also known commercially as “slaked lime.” It is used where space is an issue. Although it is also a strong alkali, it is more stable than calcium oxide. It is most often used as a component of multi-mineral formulations or in addition to other forms of calcium (i.e., calcium citrate) to provide potency where space is an issue. It is not often used as a single ingredient in health food supplementation. This is for people who want a high dosage of calcium from a minimum amount of pills in multi-mineral formulas.

Calcium Carbonate (CaCO3): at 40 percent elemental calcium, it is the most widely used form of calcium in single ingredient calcium supplements as well as combination supplements. Inexpensive and an abundant source of elemental calcium, it is the only form of calcium found in nature outside of bone. It is the primary form of calcium used in the mass market and in antacid products. This is for people who have high stomach acid and who need a buffering type of calcium. Also for people who want a high dose of calcium in a minimum amount of pills.

Calcium Citrate: at 21 percent elemental calcium, it is one of the most popular forms of calcium supplements in the health food market as well as the mass market. This calcium salt does not lower stomach acid as much as calcium carbonate. This calcium salt is usually recommended for people who have low stomach acid, have had stomach surgery or who need a form of calcium that will not lower their stomach acid further.

Calcium Gluconate and Lactate: these two forms of calcium are high soluble. Since the amount of elemental calcium is much lower (9 percent and 13 percent respectively), they are used more often in powder form and mixed with liquids or food. When mixed in a beverage, the calcium is already dissolved and is ready to be absorbed. This is the best calcium salt for people who have overactive bowels, who have trouble swallowing pills or who don’t like the taste of pre-formed liquid calcium supplements. These calcium powders can be mixed in juices or smoothies or added to food as they are virtually tasteless.

Calcium Orotate and Asporotate: In the mid 20th century, Dr. Hans Nieper, a German scientist, advanced a theory that orotic and aspartic salt forms of calcium are transported directly to cell membranes for better absorption. The Solaray brand developed an asporotate formula, which combines three organic acids: aspartic acid (-Asp), orotic acid (-oro) and citric acid (-tate) into one product. The asporotate formula has become one of the most popular calcium formulas and is exclusive to the Solaray brand. This product is for customers who appreciate the idea of combining the enhanced absorbability of three organic acids into one. Aspartate and citrate are also part of the krebs (energy) cycle and are natural to the body’s metabolic systems and, according to Neiper, calcium Orotate and Aspartate are mineral transporters that enter into the cells to facilitate enzymatic actions rather than being extra-cellular. For people who believe that intracellular calcium is of importance, calcium Orotate and asporotate may be good choice.

Calcium Hydroxyapatite: this is another “natural form of calcium usually as a mineral ash form bovine source bone. Bone meal is also a form of calcium from bovine bone. These forms of animal derived calcium are for customers who want a source that is closest to their own bone matrix. Not for vegetarians.

Calcium Amino Acid Chelates (*HVP): this form is calcium carbonate bonded (Chelated) to a form of amino acid complex such as whole rice concentrate or other grain source. This form is for customers who want the additional bioavailability of amino acids.

Calcium AEP: Another form of calcium endorsed by Dr. Hans Nieper who theorized that calcium would cross the cell membranes more readily when it was combined with phosphatidyl ethanolamine or Amino Ethanol Phosphate (AEP), a nutrient found in nerve sheaths. This highly specialized form is for very educated customers who are proponets of Hans Niepers theory.

So, which form is best?

Calcium, like cars, comes in a variety of forms. Isn’t it wonderful that we have so many choices? The point is, there is no best one, there are only individual choices. Although we have our favorites, taking a calcium supplement, regardless of which one it is, should:

• Be a matter of personal choice based on how our body feels when taking it.
• Be in a form that is most convenient or appetizing so that we receive our daily requirements.
• Take into consideration any personal body limitations we might have .

Our primary concern when choosing a calcium supplement should be to provide our body with the right amount of calcium daily so that our skeleton and teeth can maintain proper mineralization and strength as the cells continuously break down and rebuild. The type of calcium complex we prefer is entirely up to us.

*HVP = Hydrolyzed Vegetable Protein

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Date: June 19, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The healing power of borage oil

Borage oil, extracted from the seed of the blue, star shaped borage flower, is gaining much attention by alternative health practitioners and main stream medicine alike for its profound medicinal properties. Whereas the oil is getting all the redit, it is actually the oil’s active component, gamma linoleic acid (GLA), which has drawn the interest of researchers. The majority of the early studies done on GLA, dating back to the late 1940’s, were conducted with the oil of evening primrose. For rezones cited in the title, more bank for the buck, borage seed oil is now thought to be s superior source of GLA compared to evening primrose oil. Other plants forms and food concentrates that contain appreciable amounts of GLA include black currant seed oil and spirulina.

Why GLA Supplementation?

A body with healthy biochemistry has the ability to produce GLA from the most essential fat linoleic acid. Linoleic acid is found most abundantly in the omega 6 family of oils, including safflower, sunflower, and corn oil. While it has been estimated that a majority of Americans and Europeans consume far to many omega 6 fatty acids in proportion to the beneficial omega 3 fatty acids (by approximately 10:1). Most biochemists agree optimal ratio of omega 6 to omega 3 fatty acids should be approximately 1:1. Despite the obvious over consumption of omega 6 oils rich in linoleic acid, some individuals lack the ability to convert linoleic acid to the much needed GLA.

As is the example with many of our modern day nutrient deficiencies, the adulteration of our food supply by today’s processing methods has much to do with the faulty fat metabolism suffered by many. A prime example is the hydrogenation process utilized to convert liquid polyunsaturated oils into semi-solid, altered saturated fats for use as margarine and commercially processed foods. hydrogenation is accomplished by subjecting the oils to temperatures in excess of 250 C, and bombarding them with hydrogen ions in the presence of the heavy metal nickel, which irreversibly changes the chemical structure of the fatty acid molecule from a healthful “cis” configuration to a dangerous “trans” configuration. When these products are eaten in excess they are known, in some cases, to block the enzymatic conversion of linoleic acid to GLA. In addition to the damaging effects of hydrogenation, certain essential fatty acid nutrient cofactor deficiencies may exist to further complicate the conversion. Vitamins pro-A, A, C, E, B-2, B-3, B-6, pantothenic acid, B-12 biotin and the minerals calcium, magnesium, potassium, sulfur and zinc are all involved in essential fatty acid (EFA) metabolism.

Particular interest should be given to those afflicted with diabetes, cystic fibrosis, asthma, alcoholism, multiple sclerosis. For a myriad of reasons, including cofactor deficiencies, these individuals lack the enzymatic ability to convert linoleic acid to GLA and must obtain a direct source of GLA for proper hormonal regulation. In addition, excessive consumption of animal fats containing acachidonic acid competes for the same metabolic pathways occupied by GLA, thus minimizing its biological action.

These potential negating effects can simply be diverted to consuming a food source or supplement containing GLA which bypasses any previously necessary enzymatic conversion and floods the metabolic pathways with beneficial GLA. Nutrient deficiency should also be addressed. Here lies the true power of GLA.

Prostaglandins, biochemical regulators

Whereas GLA is the power, the prostaglandins deliver the punch in this biological equation. Just as linoleic acid is normally converted to GLA, GLA is further converted into the prostaglandin E1 (PGE1). Many of the benefits derived from GLA supplementation are a result of the hormonal regulatory action of the prostaglandins. Just like the “parent” precursors they are made from, the hormone-like prostaglandins orchestrate a host of important biochemical activities. Their general regulatory effects include the control of arterial muscle tone, sodium excretion through the kidneys, blood platelet “Stickiness,” inflammatory response and the immune function, just to name a few. The list may be endless as scientists continue to discover the regulating effects of prostaglandins. One way in which GLA has shown to decrease the probability of allergic and inflammatory conditions is by competing with arachidomic acid, which when left unchecked may potentiate a hyperimmune response.

Healing Power

As a result of the powerful regulating effects derived from the conversion of GLA to healthful prostaglandins, borage oil and other GLA supplements have shown to be beneficial in the treatment and relief of many classic and modern day health problems. The disease of diabetes, cystic fibrosis, asthma, multiple sclerosis are thought to be helped by bringing about a balance in an otherwise faulty fatty acid metabolism. According to a study released in the journal diabetes care, supplementation with GLA has shown promise in the reversal of diabetic neuropathy (a condition where the nerves degenerate and symptoms of pain and numbness follow). The study concluded that all diabetics should be considered for dietary protocol of GLA. Other conditions shown to benefit include high blood pressure, high cholesterol, skin conditions, arthritis, allergies, weight loss, improved behavior of hyperactive children and increased strength of hair and nails. Cited in the book, Super Nutrition For Menopause, written by the renowned nutritionist Ann Louise Gittleman, is one of the most popular applications of GLA supplementation in the relief of menstrual pain. Sufferers use a maintenance does up to the seventh day prior to menstruation, then double the dose for the duration of their menstruation. Dietary restrictions of meat, dairy and eggs during this time has also shown to compliment this regiment. Many would agree with Ms. Gittleman’s credo in allowing mother nature to cure our ails before relying on synthetic drugs which often come with side effects.

More Bang for the Buck

Now comes the challenge of acquiring a GLA supplement suited to meet your needs. With the help of the information below you may maximize your desired result while at the same time stretching your dollars. Lets take a look at the facts. We will limit out narrative to the tree most popular forms of GLA supplementation: 1) borage oil, 2) evening primrose oil and 3) black current seed oil. Potency is an important factor, as the higher the GLA content per gram, the more likelihood of greater biological activity. Borage oil contains 24% GLA, or 240mg per 1000 mg capsules. Black current seed oil contains 18%, or 180mg per 1000 mg capsule and evening primrose oil contains 10% GLA, or 100mg per 1000 mg capsule. While black currant seed may appear to run a close second to borage and have a slight edge on evening primrose, it contains a potent GLA inhibitor and should be considered last on the list. equally, if not more important than potency, is purity. Make it a practice not to purchase any oil product unless full disclosure of the method of extraction is printed on the label. If it is not, you may assume that the oil has been extracted in one of the following ways. Unfortunately, the popular use of the chemical hexane to extract oils is not required for disclosure. This method employs submerging cracked seed in a gasoline like substance (Hexane) and then slowly allowing it to evaporate off yielding 90% oil recovery. This is the most common method used to extract evening primrose oil because of the incredibly small, hard seed and low oil content. The second creative ploy is the claim that the oil has simply been extracted by a new high-tech method called supercritical fluid extraction (SCFE). This process “pregrinds” the seeds then subjects them to pressures of 6000 – 10000 psi in the presence of the gas CO-2. Under such intense pressure CO-2 gas becomes a liquid in which the seeds are submerged, ultimately yielding a 95% oil recovery. Look for oils that are labeled as “expeller pressed” without the damaging effects of light, heat and oxygen. The products should be contained in opaque (light resistant) bottles to protect them from the damaging effects of light. Optimally, you should find them in the refrigerated section of your local health food store. Due to the higher percentage of oil contained in the borage seed, as compared to evening primrose and black current, borage is typically priced well below the others making it the most potent and economical choice. All things considered an expeller pressed borage oil, contained in an opaque plastic bottle, may provide you the absolute best source of unadulterated GLA supplementation.

One company that provides such a product and always fulfills the quality requirements listed is Barlean’s Organic Oils. Their organic flax oil and borage oils are available at VitaNet.

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Date: February 08, 2006 06:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NEW PRODUCT ANNOUNCEMENT

Extra Virgin Coconut Oil Softgels A Healthy, Natural Oil with Medium Chain Fatty Acids

• Quick metabolism into energy, not stored in the body as fat as long chain fatty acids are.
• Healthy, natural replacement for processed, hydrogenated oils.
• Perfect addition to an overall healthy lipid program, aids immune process.
• Long used by the people of Asia and the Pacific, and used in Ayurvedic Herbalism for 4,000 years.

Each 4 softgel serving contains:
Calories 36
Calories from Fat 36
Total Fat 4g 6%
Saturated Fat 3.5g 20%
Trans Fat 0
Cholesterol 0
Organic Extra Virgin Coconut Oil 4g

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Date: December 07, 2005 05:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitaberry Plus + Super Fruit Antioxidant

Vitaberry Plus +™ Super Fruit Antioxidant

ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697

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Date: November 20, 2005 07:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Chloride: The Forgotten Essential Mineral

Chloride: The Forgotten Essential Mineral

Chloride is an “essential” mineral for humans. It is abundant in ionic trace mineral preparations. It is a major mineral nutrient that occurs primarily in body fluids. Chloride is a prominent negatively charged ion of the blood, where it represents 70% of the body’s total negative ion content. On average, an adult human body contains approximately 115 grams of chloride, making up about 0.15% of total body weight.1 The suggested amount of chloride intake ranges from 750 to 900 milligrams per day, based on the fact that total obligatory loss of chloride in the average person is close to 530 milligrams per day. As the principle negatively charged ion in the body, chloride serves as one of the main electrolytes of the body. Chloride, in addition to potassium and sodium, assist in the conduction of electrical impulses when dissolved in bodily water. Potassium and sodium become positive ions as they lose an electron when dissolved and chloride becomes a negative ion as it gains an electron when dissolved. A positive ion is always accompanied by a negative ion, hence the close relationship between sodium, potassium and chloride. The electrolytes are distributed throughout all body fluids including the blood, lymph, and the fluid inside and outside cells.2 The negative charge of chloride balances against the positive charges of sodium and potassium ions in order to maintain serum osmolarity.

Pivotal Roles of Chloride in the Body

In addition to its functions as an electrolyte, chloride combines with hydrogen in the stomach to make hydrochloric acid, a powerful digestive enzyme that is responsible for the break down of proteins, absorption of other metallic minerals, and activation of intrinsic factor, which in turn absorbs vitamin B12. Chloride is specially transported into the gastric lumen, in exchange for another negatively charged electrolyte (bicarbonate), in order to maintain electrical neutrality across the stomach membrane. After utilization in hydrochloric acid, some chloride is reabsorbed by the intestine, back into the blood stream where it is required for maintenance of extracellular fluid volume. Chloride is both actively and passively absorbed by the body, depending on the current metabolic demands. A constant exchange of chloride and bicarbonate, between red blood cells and the plasma helps to govern the pH balance and transport of carbon dioxide, a waste product of respiration, from the body. With sodium and potassium, chloride works in the nervous system to aid in the transport of electrical impulses throughout the body, as movement of negatively charged chloride into the cell propagates the nervous electrical potential.

Deficiency of Chloride

Deficiency of chloride is rare. However, when it does occur, it results in a life threatening condition known as alkalosis, in which the blood becomes overly alkaline. A tedious balance between alkalinity and acidity is in constant flux, and must be vigilantly maintained throughout the entire body. Alkalosis may occur as a result of excessive loss of sodium, such as heavy sweating during endurance exercise, and in cases of prolonged vomiting and diarrhea. Symptoms include muscle weakness, loss of appetite, irritability, dehydration, and profound lethargy. Hypochloremia may result from water overload, wasting conditions, and extensive bodily burns with sequestration of extracellular fluids. In a situation in which infants were inadvertently fed chloride-deficient formula, many experienced failure to thrive, anorexia, and weakness in their first year of life.3

Excess Intake?

Excessive intakes of dietary chloride only occur with the ingestion of large amounts of salt and potassium chloride. The toxic effects of such diets, such as fluid retention and high blood pressure, are attributed to the high sodium and potassium levels.4 Chloride toxicity has not been observed in humans except in the special case of impaired sodium chloride metabolism, e.g. in congestive heart failure.5 Healthy individuals can tolerate the intake of large quantities of chloride provided that there is a concomitant intake of fresh water. Other situations in which increased blood levels of chloride are seen include diseases of improper waste elimination that occur in kidney diseases. Excess chloride is normally excreted in the urine, sweat, and bowels. In fact, excess urinary excretion of chloride occurs in high salt diets. Excessive intakes of chloride can occur in a person with compromised health in addition to an unhealthy diet. However, those that follow a healthy diet and lead an active lifestyle may need to consider supplementing their diet with this important mineral.

Chloride vs. Chlorine

The mineral supplement chloride is very different from the gas chlorine. While elemental chlorine is a dangerous gas that does not exist in the free elemental state in nature because of its reactivity, although it is widely distributed in combination with other elements. Chloride is related to chlorine however, as one of the most common chlorine compounds is common salt, NaCl. Chloride is a by-product of the reaction between chlorine and an electrolyte, such as potassium, magnesium, or sodium, which are essential for human metabolism. Chloride salts are essential for sustaining human metabolism and have none of the effects of isolated chlorine gas.

Sources of Chloride

Chloride occurs naturally in foods at levels normally less than 0.36 milligrams per gram of food. The average intake of chloride during a salt-free diet is approximately 100 milligrams per day. Unfortunately, chloride is found commonly combined with undesirable dietary sources. The most common of these negative sources is table salt. Table salt is made from a combination of sodium and chloride ions. Other unhealthful sources include yeast extracts, processed lunchmeats, and cheeses. Healthier sources of chloride include kelp (seaweed), ionic trace minerals, olives, rye, tomatoes, lettuce, and celery, although not in large enough amounts to supply the needs of an active adult.6 In its original form, however, chloride is leached from various rocks into soil and water by years of weathering processes. The chloride ion is highly mobile and is transported to closed basins, such as the Great Salt Lake, or oceans.7

Summary

Chloride is a highly important, vital mineral required for both human and animal life. Without chloride, the human body would be unable to maintain fluids in blood vessels, conduct nerve transmissions, move muscles, or maintain proper kidney function. As a major electrolyte mineral of the body, chloride performs many roles, and is rapidly excreted from the body. Active adults that eat a healthy diet devoid of salt and illnesses in which vomiting and/or diarrhea are profuse warrant the supplementation of additional chloride. Replacement of chloride is essential on a daily basis to maintain regular metabolic function. Chloride is safely utilized by the body, without negative health effects. Of the negative health effects that have been associated with diets high in chloride, these are mainly attributable to the accompanying sodium and potassium, two other electrolyte minerals to which chloride is often attached

--------------------------------------------------------------------------------

1 Wesson LG. Physiology of the human kidney. New York, NY, Grune and Stratton, 1969: 591

2 Weast RC, ed. CRC handbook of chemistry and physics, 67th ed. Boca Raton, FL, CRC Press, 1986.

3 Kaleita TA. Neurologic/behavioral syndrome associated with ingestion of chloride-deficient infant formula. Pediatrics 1986 Oct;78(4):714-5

4 Beard TC. A salt-hypertension hypothesis. J Cardiovasc Pharmacol 1990;16 Suppl 7:S35-8

5 Seelig M. Cardiovascular consequences of magnesium deficiency and loss: pathogenesis, prevalence and manifestations--magnesium and chloride loss in refractory potassium repletion. Am J Cardiol 1989 Apr 18;63(14):4G-21G

6 Altschul AM, Grommet JK. Food choices for lowering sodium intake. Hypertension 1982 Sep-Oct;4(5 Pt 2):III116-20

7 Gelb SB, Anderson MP. Sources of chloride and sulfate in ground water beneath an urbanized area in Southeastern Wisconsin (Report WIS01 NTIS). Chemical abstracts, 1981, 96(2):11366g.

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Date: October 29, 2005 01:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Feds Subsidized Poor Nutrition

Feds Subsidized Poor Nutrition

The U.S. Department of Agriculture (USDA) this year issued a new food pyramid aimed at convincing Americans to eat more fruits, vegetables, whole grains, and lean proteins such as dairy, meat and beans. While the USDA publicizes its pyramid with much fanfare, the agency implements policies that subsidize the consumption of nutrition-poor, high fat and processed foods, while offering no incentive to farmers to grow healthful crops.

The Pyramid Versus Farm subsidies

A recent Associated Press (AP) article* contrasted the pyramid recommendations with a breakdown of this year’s $17 billion in direct subsidies to farmers.

Other food crops receive less than 1% each, and fruit and vegetables receive none.

Overproduction Leads to Lower Prices

U.S. farm policy leads to the overproduction of nutrition-poor, fat and starch-laden foods. As a result, the prices of these foods go down, while healthy food remains less affordable.

A related AP story describes the barriers faced by poor families who would prefer a more nutrition’s diet but end up eating cheap, unhealthy food. Adam Drewnowski, director of the University of Washington’s Center of public Health Nutrition is quoted: “Energy-dense foods rich in starch, sugar or fat are the cheapest option. As long as the healthier lean meats, fish and fresh produce are more expensive, obesity will continue to be a problem for the working poor.”

Food Policy and the wellness Revolution

With obesity and related health problems at a crisis point, some consumer advocates are trying to change our government’s food policies. An effective response to the current dietary crisis requires political charge as well as education about healthy lifestyles. Meanwhile, it is a wise strategy for individuals to develop a personal, nutritional supplement regimen. The centerpiece of this program should be a scientifically advanced and comprehensive multiple such as Source Naturals Life Force.

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The “Power” of trace Minerals…

Date: October 08, 2005 11:56 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The “Power” of trace Minerals…

The “Power” of trace Minerals…

These articles piqued hartley’s interest with information about the amazing results people were receiving from drinking a little bit of sea water each day. This led him to research the great salt Lake, an inland sea located near his home. He found that the Great Salt Lake not only had the same minerals and balance discussed by George Crane, but that it was 6 to 10 times more concentrated than regular sea water without the pollution. Hartley knew there was a need for these minerals himself and had seen results from other people that the company was established with initial product sales.

Science was slow to provide answers as to why the minerals from this desert sea caused such a dramatic and varied results in people, but Hartley knew from his growing stack of testimonials that the company’s first product, Inland sea water, was effective. He and his wife, Gaye, founded Trace Minerals Research in 1968 and started selling pure Great Salt Lake water to the public and a short time later, they discovered how to use nature’s own processes to remove the sodium, thereby creating low-sodium, Concentrace TraceMineral Drops.

Hartley and Gaye founded their company on the principle that nutritional supplements should get results and that if a customer does not actually feel an improvement in their health, they should not have to pay for it. This same principle is still evident today in Trace Mineral Research.

Not a single bottle of product leaves our manufacturing facility unless we can confidently back it up with the guarantee of “Feel the Difference or your Money Back.” This guarantee is made possible because minerals and trace minerals needed by Americans today are found in rich abundance, a natural balance and a highly assimilable principle ionic form from the Great Salt Lake. Trace Mineral Research sent most of their products into development because of the spectacular results many people were already discovering from low sodium ConcenTrace and Trace Mineral Drops. The company then combined their formulas of vitamins, herbs, enzymes and other nutrients to enhance the specific benefits people were reporting.

Trace Minerals Research now has a complete line of highly effective nutritional supplements each backed by our guarantee of “Feel the Difference of Your Money Back”. These products are also backed by research and we are continually researching new information on our existing and new products.

Our Philosophy at Trace Mineral Research has always been that the Earth was created with the prefect balance of all the nutrients that humans need to be healthy and happy. The only problem is that over the years humans have become victims of the water cycle. Dr. U. Aswathanarayana states, “Soil erosion leads to the depletion of essential nutrients elements in crops grown in depleted soil. When people consume a diet derived from such crops, the intake of essential elements becomes inadequate. This leads to the impairment of the relevant physiological functions, and causes disease.” For millions of years, every sprouting seed and towering tree has dissolved minerals to ionic form and raised them from the depths of the soil where they could easily be washed away by water. To add to this problem, aggressive farming has further depleted the soils. Furthermore, many fertilizers and pesticides bind trace minerals in the soil so that fewer minerals are absorbed by fruits and vegetables. The importance of minerals in the soil and their effects on human health are not new concepts. Dr. Alexis Carrel, Winner of the Nobel Prize in Medicine in 1912, states, “Soil is the basis of all human life and our only hope for a healthy world… All of life will be either healthy or unhealthy according to the fertility of the soil. Minerals in the soil control the metabolism of cells in plants, animal and man … Diseases are created chiefly by destroying the harmony reigning among mineral substances present in infinitesimal amounts in air, water and food, but most importantly in the soil. Even the AMA recognized the importance of minerals in our diet. “Variations in the distribution of certain minerals in the environment are known to have an effect on health.

The Lack of minerals in our soil is evidenced through the need for constant fertilization. Plants need nitrogen, hydrogen, oxygen, chlorine, carbon, boron, sulfur, potassium, magnesium, phosphorous, iron, zinc, copper, manganese, and molybdenum, some of which are commonly replaced through fertilizers to provide maximum crops through minimum investment. However, humans are known to additionally need calcium, sodium, fluorine, bromine, chromium, iodine, silicon, selenium, beryllium, lithium, cobalt, vanadium and nickel, which would not necessarily be replaced through fertilization for plants.

This continual cycle of soil depletion and minor replacement of minerals through fertilization in conjunction with a diet of processed foods has left many Americans deficient in minerals and trace minerals. This does not need to follow the water cycle. As water goes through the constant cycle from evaporation to precipitation, minerals are transported through rivers and streams where it is then collected in the seas thereby creating a natural equilibrium.

Today, Trace Minerals Research harvests minerals and trace minerals from the Great Salt Lake, a uniquely rich and pure desert sea. These minerals are the basis for each of their unique products and help provide a strong foundation for balanced supplementation.

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PepZin GI™ helps relieve occasional discomfort.

Date: September 20, 2005 05:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PepZin GI™ helps relieve occasional discomfort.

PepZin GI™ helps relieve occasional discomfort.* CLINICAL TRIALS

In a randomized, multi-center, placebo-controlled double blind study, 299 patients suffering with symptoms of gastric discomfort were randomly allocated to receive either a zinc-L-carnosine complex or a placebo, or a control drug or its placebo for 8 weeks. Improvement ratings for a range of symptoms were taken at various points during the trial and compared with before treatment data. Of the 258 people who completed the trial, 136 were in the zinc-Lcarnosine group. Of the group, 92% of the participants were rated as “moderately improved” or better on an improvement scale across the category of symptoms including heartburn, tenderness, epigastric pain, diarrhea and constipation after 8 weeks.3

In another study, 28 patients with gastric discomfort were given a zinc-L-carnosine compound and monitored for 8 weeks. Improvement was rated on a scale of subjective and objective symptoms. After 4 weeks, the rate of those cases that were considered to be “significantly improved” was 68.4%. After eight weeks, the “significantly improved” number was 68.8%. Over 60% of these patients remained in the “significantly improved” category well after discontinuation of the treatment, suggesting a lasting effect of the zinc-L-carnosine compound beyond the time it is taken.4

Maintains a healthy GI environment.*

The mineral zinc in PepZin GI™ is a critical component to a number of physiological processes in our bodies. Some of these functions include growth and metabolism of cells, healing of wounds,and maintenance of carbohydrate and lipid metabolism.2

PepZin GI™ may also be able to favorably maintain the bacterial balance of the stomach and GI tract. Studies suggest that the zinc-L-carnosine co m pound may have effects on certain strains of harmful bacteria and, therefore, may be able to help maintain a GI environment that is favorable to health.1 By supporting the bacterial balance in the stomach, PepZin GI™ can help maintain a healthy mucosal lining.

Supports the health of gastric cells.*

PepZin GI™ has been studied for its ability to prevent free radical damage to gastric cells. In one such study, rat gastric cells were exposed to ethanol and hydrogen peroxide, two substances known to cause free radical damage to living cells. Cells were bathed in hydrogen peroxide, ethanol, zinc-L-carnosine, or a combination of zinc-L-carnosine with either ethanol or hydrogen peroxide. While the cells bathed in ethanol and hydrogen peroxide solutions all exhibited signs of damage due to free radical production, the cells that were bathed in zinc-L-carnosine were largely protected from the effects of free radical damage. The authors concluded that the zinc compound directly protected gastric mucosal cells from oxidant stress and alcohol induced damage.5

Additional research further confirms the gastro-protective effects of PepZin GI™. In another rat study, stomach lesions were induced by administration of the chemical monochloramine, a known pro-oxidant (producer of free radicals). One of the groups of rats was fed the zinc-Lcarnosine compound prior to being exposed to monochloramine. The researchers found that the size of the lesions in the group pre-treated with zinc-L-carnosine was significantly less than the lesions in the control group. The authors concluded that the zinc compound exerted a beneficial protective effect against monochloramine-induced stomach lesions.6

The zinc-L-carnosine in PepZin GI™ has also been shown to slow the development of aspirin induced stomach damage in rats. The researchers measurably detected lower levels of TNF-alpha in rats given zinc-L-carnosine as compared to the control rats. TNF-alpha is an inflammatory cytokine that is known to be released in response to gastric damage.7 These results may suggest a role for PepZin GI™ in protecting gastric cells by occasionally reducing the levels of certain cytokines in minor inflammation of the stomach.

Scientific References

1. Kuwayama H, et al. Polaprezinc. Nippon Rinsho 2002 Feb; 60 Suppl 2:717-720. 2.Matsukura T,Tanaka H. Applicability of zinc complex of l-carnosine for medical use. Biochemistry (Moscow) 2000;65(7):817-823. 3.Miyoshi A, et al. Clinical evaluation of Z-103 on gastric ulcer - a multicenter double-blind comparative study with cetraxate hydrochloride. Jpn PharmTher 1992;20(1):199-223. 4.Misawa T, et al. Clinical study of Z-103 - clinical effects on gastric ulcer and influence on endocrine function. Jpn PharmTher 1992; 20(1):245-254. 5. Hiraishi H, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacl Ther 1999;13:261-269. 6. Kato S, Nishiwaki H, et al. Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Dig Dis Sci 1997;42(10):2156-2163. 7.Naito Y, et al. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci 2001;46(4):845-851.

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Curcumin - Turmeric Extract

Date: August 19, 2005 12:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curcumin - Turmeric Extract

Curcumin

Turmeric- History and Traditional Usage

Native to Southeast Asia, Curcuma longa is a tall
tropical shrub with large oblong leaves and pale yellow flowers.
The genus “Curcuma” belongs to the Zingiberaceae family, which
includes ginger.1 The plant possesses a large root structure
with fleshy, bulbous underground parts called “rhizomes.” These
rhizomes, known as turmeric root, are harvested at maturity,
dried and cured for commercial use. Chemical analysis shows that
dried turmeric contains essential and volatile oils, with a
curcuminoid content of 2.5 to 5.0 %.2

In addition to its
popularity as a spice, turmeric is used as a dye for cloth and
coloring agent in foods and cosmetics, thanks to its rich yellow
color. Turmeric also serves as a preservative, probably owing to
the antioxidant and antimicrobial properties of curcumin.
Extracts of Curcuma longa have demonstrated in vitro
antibacterial and anti-fungal effects.3

Turmeric is named in
ancient Ayurvedic and Chinese herbal texts as a traditional folk
remedy. Historically, turmeric was used externally for wounds,
and sprains, and internally for digestive complaints,
rheumatism, liver disorders, coughs and colds.4
Benefits

Protects cells and tissues by fighting free radicals.*

Supports joint function*

The numerous beneficial
effects attributed to turmeric stem in large measure from the
antioxidant properties of curcumin. Antioxidants neutralize free
radicals, which are highly unstable molecules that can damage
cellular structures through abnormal oxidative reactions.
Curcumin is a potent “scavenger” of the superoxide radical, a
free radical that initiates potentially harmful oxidative
processes such as lipid peroxidation.5 Through this activity,
curcumin has been shown to protect skin cells from the injurious
effect of nitroblue tetrazolium, a toxin that generates
superoxide radicals. Curcumin also increases survival of cells
exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
which stimulates superoxide and hydrogen peroxide production.
Curcumin itself is not toxic to cells, even at high
concentrations. Pure curcumin was shown to be less protective
than a mixture of curcuminoids, indicating a possible synergism
among curcuminoids.6 Because free radicals are involved in aging
and exert harmful effects on skin, these results suggest
curcumin may help slow skin aging.

Curcumin demonstrates
several other in vitro effects linked to free radical
scavenging. Curcumin scavenges nitric oxide, a compound
associated with the body’s inflammatory response.7 Pure curcumin
and turmeric extracts protect red blood cells from lipid
peroxidation induced by hydrogen peroxide.8 Curcumin has been
shown to protect DNA from oxidative damage, inhibit binding of
toxic metabolites to DNA, and reduce DNA mutations in the Ames’
test.9 Although additional studies suggest an anticarcinogenic
effect of curcumin, through protection of DNA,10 one in vitro
study found that curcumin induced DNA damage in human gastric
mucosal cells.11 It is speculated that curcumin may act as a
pro-oxidant in the presence of transition metal ions such as
copper and iron. (This is true for other antioxidants, including
vitamin C.) Curcumin also demonstrates in vitro inhibition of
COX-I and COX-II enzymes, which are involved in the inflammatory
reaction.12 Together these results strongly suggest that
curcumin is a potent bioprotectant with a potentially wide range
of therapeutic applications.

Animal studies- In vivo protective effects

Through its free radical scavenging
properties, curcumin has shown bioprotective effects in animals.
In one study, rats were treated with isoproterenol, a chemical
that causes cardiac hypertrophy (enlargement of the heart) due
to abnormal collagen metabolism. Co-treatment with curcumin
reversed the degradation of collagen and cardiac hypertrophy
induced by isoproterenol.13 Curcumin protects mice from
detrimental effects of radiation, by stabilizing the glyoxalase
system, a biological system that regulates cell division.14
Curcumin protects livers of rats from the damaging effects of
carbon tetrachloride (CCl4), a potent hepatoxin that injures the
liver via its free radical metabolite, CCl3.15,16 Curcumin
protected rats from alcohol-induced brain damage, in a study in
which oral administration of curcumin reversed lipid
peroxidation, reduced levels of free-radical metabolites and
increased levels of glutathione, a major physiologic
antioxidant.17 Curcuma longa extracts have shown
anti-inflammatory effects in rats.18

Human Trials

Curcumin exhibits free-radical scavenging ability when
administered to humans. In an open trial (uncontrolled), 18
healthy individuals ranging in age from 27 to 67 years consumed
a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
for 45 days. Before and after blood tests showed a statistically
significant decrease in lipid peroxides.19 Preliminary trials
have tested the anti-inflammatory action of curcumin, with
results that verify the traditional use of turmeric as an
anti-rheumatic herb. In a short-term double-blind, cross-over,
comparative study, 18 people received curcumin (1200 mg daily)
or phenylbutazone for two week periods. Both curcumin and
phenylbutazone produced measurable improvements in joint
flexibility and walking time. The subjects reported results only
with phenylbutazone, which may be explained by the short
duration of the trial.20 In a small placebo-controlled trial
comparing curcumin to phenylbutazone, 45 patients with
post-operative inflammation received curcumin, phenylbutazone or
placebo. The anti-inflammatory effects of curcumin and
phenylbutazone were comparable and superior to placebo.21
Curcumin has not been found to produce an analgesic (pain
relieving) effect.

Bioperine-Nature’s Absorption Enhancer
Boosts Curcumin Absorption*

Traditional Ayurvedic herbal
formulas often include black pepper and long pepper as
synergistic herbs. The active ingredient in both black pepper
and long pepper is the alkaloid, piperine. Experiments carried
out to evaluate the scientific basis for the use of peppers have
shown that piperine significantly enhances bioavailability when
consumed with other substances.22 Several double-blind clinical
studies have confirmed that Bioperine® increases absorption of
nutrients.23

Curcumin is poorly absorbed in the intestinal
tract, limiting its therapeutic effectiveness. Oral doses are
largely excreted in feces, and only trace amounts appear in the
blood. Concomitant administration of 20 mg of piperine with 2
grams of curcumin increases the bioavailability of curcumin by
2000%.24

Scientific References

1. Majeed, M., Badmaev,
V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
Piscataway, NJ: NutriScience Publishers.
2. Srimal, R.C.
Turmeric: a brief review of its medicinal properties.
Fitoterapia 1997;68(6):483-93.
3. Ammon, H.P.T., Wahl, M.A.
Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
4.
Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
The Protocol Journal of Botanical Medicine, Autumn
1995:43-46.
5. Rao, N.S., Rao, M.N.A. Free radical scavenging
activity of curcuminoids. Arzneim.-Forsch./Drug Res.
1996;46(2):169-171.
6. Bonté. F. et al. Protective effect of
curcuminoids on epidermal skin cells under free oxygen radical
stress. Planta Medica 1997;63:265-66.
7. Rao, S., Rao, M.N.A.
Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol.
1997;49:105-7.
8. Lalitha, S., Selvam, R. Prevention of
H2Os-induced red blood cell lipid peroxidation by aqueous
extracted turmeric. Asia Pacific J Clin Nutr
1999;8(2):113-14.
9. Deshpande, S.S., Maru, G.B. Effects of
curcumin on the formation of benzo[a]pyrene derived DNA adducts
in vitro. Cancer Letters 1995;96:71-80.
10. Subramanian, M., et
al. Diminution of singlet oxygen-induced DNA damage by curcumin
and related antioxidants. Mutation Research
1994;311:249-55.
11. Blasiak, J., Trzeciak, A., Kowalik, J.
Curcumin damages DNA in human gastric mucosa cells and
lymphocytes. Journal of Environmental Pathology, Toxicology and
Oncology 1999;18(4):271-76.
12. Ramsewak, R.S., DeWitt, D.L.,
Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
activities of Curcumins I-III from Curcuma longa. Phytomedicine
2000;7(4):303-308.
13. Nirmala, C. Anand, S., Puvanakrishnan,
R. Curcumin treatment modulates collagen metabolism in
isoproterenol induced myocardial necrosis in rats. Molecular and
Cellular Biochemistry 1999;197:31-37.
14. Choudhary, D.,
Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
system by curcumin. Journal of Ethnopharmacology
1999;64:1-7.
15. Park, E-J. et al. Protective effect of
curcumin in rat liver injury induced by carbon tetrachloride. J
Pharm. Pharmacol. 2000;52:437-40.
16. Deshpande, U.R. et al.
Protective effect of turmeric (Curcuma longa L.) extract on
carbon tetrachloride-induced liver damage in rats. Indian
Journal of Experimental Biology 1998;36:573-77.
17.
Rajakrishnan, V. et al. Neuroprotective role of curcumin from
Curcuma longa on ethanol-induced brain damage. Phytotherapy
Research 1999;13:571-74.
18. Arora, R.B. Basu, N., Kapoor, V.,
Jain, A.P. Anti-inflammatory studies on Curcuma longa
(Turmeric). Indian J Med Res 1971;59(8):1289-95.
19.
Ramirez-Bosca, A. et al. Antioxidant curcuma extracts decrease
the blood peroxide levels of human subjects. Age
1995;18:167-69.
20. Deodhar, S.D., Sethi, R. Srimal. R.C.
Preliminary study on antirheumatic activity of curcumin
(diferoyl methane). Indian J Med Res 1980;71:632-34.
21.
Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
anti-inflammatory property of curcumin (diferoyl methane) in
patients with postoperative inflammation. International Journal
of Clinical Pharmacology, Therapy and Toxicolgy
1986;24(12):651-54.
22. Atal, C., Zutshi, U., Rao, P.
Scientific evidence on the role of Ayurvedic herbals on
bioavailability of drugs. Journal of Ethnopharmacology
1981;4:229-232.
23. Bioperine®–Nature's Bioavailability
Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
Corporation, Piscataway, N.J.
24. Shoba, G., et al. Influence
of piperine on the pharmacokinetics of curcumin in animals and
human volunteers. Planta Medica 1998;64(4):353-6.

© 2002
Doctor's Best, Inc. Revised 8/13/02

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)

Date: August 02, 2005 03:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benfotiamine raises the blood level of thiamine pyrophosphate (TPP)

Benefits

Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine.4

Thiamine and its Co-enzyme, TPP

Thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically-catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name "thiamine diphosphate." In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as "active acetate." Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle (citric acid cycle). The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called "oxidative decarboxylation," and for this reason, TPP was originally referred to as "cocarboxylase." TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.

Benfotiamine and Glucose Metabolism Benfotiamine normalizes cellular processes fueled by glucose metabolites.

As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the Krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.5 In the presence of elevated glucose levels, the electron transport chain, the final ATP-generating system in the mitochondrion, produces larger than normal amounts of the oxygen free radical "superoxide." This excess superoxide inhibits glyceraldehyde phosphate dehydrogenase (GAPDH), as key enzyme in the conversion of glucose to pyruvic acid, resulting in an excess of intermediate metabolites known as "triosephosphates." Increase triosephophate levels trigger several cellular mechanisms that result in potential damage to vascular tissue. Cells particularly vulnerable to this biochemical dysfunction are found in the retina, kidneys and nerves.

Benfotiamine has been shown to block three of these mechanisms: the hexosamine pathway, the diaglycerol-protein kinease C pathway and the formation of Advanced Glycation End-poducts. As discussed below, benfotiamine does this by activating transketolase, a key thiamin-dependent enzyme.6 Benfotiamine stimulates tranketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.* Transketolase diverts the excess fructose-6-phosphate and glyceraldehydes-3-phosphate, (formed by the inhibition of GAPDH, as mentioned above), into production of pentose-5-phosphates and erythrose-4-phosphate and away from the damaging pathways. Benfotiamine activates transketolase activity in bovine aortic endothelial cells incubated in glucose.6 To test benfotiamine’s ability to counteract these metabolic abnormalities caused by elevated blood glucose, studies have been done in diabetic rats. Benfotiamine increases transketolase activity in the retinas of diabetic rats, while concomitantly decreasing hexosamine pathway activity, protein kinase C activity and AGE formation.6

Benfotiamine and Protein glycation Benfotiamine controls formation of Advanced Glycation End-products (AGEs).

AGEs have an affinity for proteins such as collagen, the major structural protein in connective tissue. AGEs are formed through abnormal linkages between proteins and glucose. This occurs via a non-enzymatic glycosylation reaction similar to the "browning reaction" that takes place in stored food.7 At high glucose concentrations, glucose attaches to lysine, forming a Schiff base, which in turn forms "early glycosylation products." Once blood glucose levels return to normal levels, the amount of these early glycosylation products decreases, and they are not particularly harmful to most tissue proteins. On long-lived proteins such as collagen, however, early glycosylation products are chemically rearranged into the damaging Advanced Glycation End-products. AGE formation on the collagen in coronary arteries causes increased vascular permeability. This vessel "leakiness" allows for abnormal cross-linking between plasma proteins and other proteins in the vessel wall, comprising vascular function and potentially occluding the vessel lumen. A number of other potentially harmful events may also occur, including production of cytokines that further increase vascular permeability. Endothelin-1, a strong vasoconstrictor, is over produced, increasing the possibility of thrombosis and generation of oxygen free radicals is stimulated.8 It is vitally important to support normal glucose metabolic pathways so that formation of AGEs is minimized. Benfotiamine, in the test tube (in vitro) prevents AGE formation in endothelial cells cultured in high glucose by decreasing the glucose metabolites that produce AGEs.9 Endothelial cells make up the membranes that line the inner walls of organs and blood vessels. In a rat study comparing the effects of Benfotiamine with water-soluble thiamin, Benfotiamine inhibited AGE formation in diabetic rats while completely preventing formation of "glycooxidation products," which are toxic by products of chronic elevated blood glucose. AGE levels were not significantly altered by thiamin.10 Benfotiamine also normalized nerve function in the animals. After three months of administration, "nerve conduction velocity (NCV)," a measure of nerve function, was increased by both benfotiamine and thiamin; at six months, NCV was normalized by benfotiamine, whereas thiamin produced no further increases in this parameter.

Dysfunctional glucose metabolic pathways leading to AGE formation occurs in endothelial cells of the kidneys. In a recent animal study, benfotiamine was administered to rats with elevated glucose levels. Benfotiamine increased transketolase activity in the kidney filtration system of these rats, while at the same time shifting triosephophates into the pentose pathway and preventing protein leakage.11

Safety

Benfotiamine has an excellent tolerability profile and can be taken for long periods without adverse effects.3,12 The statements in this fact sheet have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1. Bitsch R, Wolf M, Möller J. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab 1991;35(2):292-6.

2. Schreeb KH, Freudenthaler S, Vormfelde SV, et al. Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate. Eur J Clin Pharmacol 1997; 52(4):319-20.

3. Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin Pharmacol Ther 1996;34(2):47-50.

4. Frank T, Bitsch R, Maiwald J, Stein G. High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine. Eur J Clin Pharmacol. 2000;56(3):251-7.

5. Pike RL, Brown ML. Nutrition, An Integrated Approach, 3rd Ed. New York:MacMillan; 1986:467.

6. Hammes H-P, Du X, Edlestein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic neuropathy. Nat Med 2003;9(3):294-99.

7. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci 1984;81(2):583-7.

8. Brownlee M. The pathological implications of protein glycation. Clin Invest Med 1995;18(4):275-81.

9. Pomero F, Molinar Min A, La Selva M, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol 2001;38(3):135-8.

10. Stracke H, Hammes HP, Werkman D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes 2001;109(6):300-6.

11. Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 2003;52(8):2110-20.

12. Bergfeld R, MatsumaraT, Du X, Brownlee M. Benfotiamin prevents the consequences of hyperglycemia induced mitochondrial overproduction of reactive oxygen specifies and experimental diabetic neuropathy (Abstract) Diabetologia 2001; 44(Suppl1):A39.

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Holy Basil - For Natural Stress Reduction and COX-2 Inhibition

Date: June 29, 2005 01:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Holy Basil - For Natural Stress Reduction and COX-2 Inhibition

Skyrocketing stress is one of our nation’s most pervasive public health problems. Daily stress can cause imbalances in inflammatory COX-2 production and cortisol levels, which can influence blood sugar changes and, ultimately, result in challenges to our health. To regain balance, Source Naturals introduces HOLY BASIL, a legendary Ayurvedic herb that is making news for its ability to inhibit the inflammatory COX-2 enzyme, balance cortisol levels and normalize blood sugar. HOLY BASIL is rich in beneficial compounds—such as rosmarinic acid and eugenol—which work together to reduce stress. This herb also typically contains ursolic acid, shown to inhibit COX-2 in in vitro research. As a result, HOLY BASIL has a positive effect on mental well-being, and can support minor pain relief from everyday activities. Source Naturals brings you this special herb, used daily in India by millions, in a high-potency, 450 mg extract tablet.

Stress, Blood Sugar and Nervous System Protection

For over five millennia, Tulsi (holy basil) has been used to improve digestion and restore imbalances of the body and mind. Now research has documented that HOLY BASIL may do this by decreasing levels of cortisol, a hormone produced and secreted by the adrenal glands. Nicknamed the “stress hormone,” cortisol production increases in response to chronic stress. Cortisol triggers the body to make glucose from amino acids, which causes blood sugar to rise. Through normalizing cortisol levels in times of stress, holy basil may prevent not only the mood changes associated with stress, but also prevent the increases in blood sugar that researchers say can contribute to numerous health imbalances affecting more than half of all Americans. HOLY BASIL has also been found to normalize neurotransmitter levels in the brain. Researchers found in animal studies that HOLY BASIL counteracted stress-induced changes in neurotransmitters and enzymes. Stress leads to a positive increase in brain serotonin levels, increases in dopamine levels and increases in SDH (succinate dehydrogenase) levels, while holy basil may help people maintain normal levels of these brain chemicals in times of stress. Another study found that animals that received the extract showed significant normalization of epinephrine, norepinephrine, serotonin, MAO, and SDH. Epinephrine and norepinephrine are used in coping with stress. The researchers suggest that when dopamine levels rise, these two neurotransmitters may be replenished since dopamine is a precursor for their synthesis. This may be the mechanism by which holy basil assists with stress adaptation.

A Powerful Adaptogen

HOLY BASIL is classified as a premier “adaptogen,” an herb that can normalize body processes and restore overall health by maintaining body systems. Adaptogens support our systemic response to stress and give us stamina. HOLY BASIL is not to be used if you are pregnant, breastfeeding, or if you may become pregnant. Taking personal responsibility for your health and exploring safe natural alternatives to support prevention is the basis for the current revolution in health care. And health food outlets are the center of this wellness revolution. It is here that Source Naturals HOLY BASIL and hundreds of other advances in nutritional science and natural health can be found.

References:
1996. Agrawal, P. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharm and Ther: 34(9): 406-409. 2001. Devi, U. Radioprotective, anticarcinogenic and antioxidant properties of the Indian Holy Basil, Ocimum sanctum (Tulsi). Ind J Exp Biol. 39:185-190. 1999. Singh, S. Evaluation of the gastric antiulcer activity of fixed oil of Ocimum sanctum (Holy Basil). J Ethnopharmacology. 65:13-19. 1997. Singh, S. Evaluation of anti-inflammatory activity of fatty acids of Ocimum sanctum fixed oil. Ind J Exp Biol. 35:380-383.

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Essential Fatty Acids - The “Good” Fats

Date: June 25, 2005 08:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Essential Fatty Acids - The “Good” Fats

All About Fats

Some people shy away from anything that has the word “fatty” associated with it. They instantly think it will cause them to gain unnecessary weight. However, there are “good fats” and “bad fats,” and the beneficial ones can actually help decrease the desire to eat the harmful ones. Fats are important for health. Also known as lipids, they help balance the body’s chemistry and provide padding as protection for vital organs. Fats provide a source of energy for body processes, and they help with the transportation and absorption of fat-soluble vitamins such as A, D, E, and K. They are also a source of the vital nutrients known as essential fatty acids. Categories of fats include the following:

SATURATED FATS: All fats are composed of carbon, hydrogen, and oxygen molecules. The carbon atoms of fatty acids hold together in a chain-like fashion. These carbon atoms can attach hydrogen to them. When each place that can hold a hydrogen atom is filled and there is not room for even one more, they are described as saturated. The longer the chain, the harder the fat will be and thus, the higher its melting point. These types of long-chain fatty acids are found in “hard fats,” such as those in red meat, butter, cheese, sour cream and palm kernel and coconut oils. When a person’s diet is high in saturated fats, these fats tend to clump together in the body and form deposits, along with protein and cholesterol. They then lodge in the cells, organs and blood vessels. This can lead to many health problems, including obesity, heart disease, and breast and colon cancers.

UNSATURATED FATS: Unsaturated fats are called such because there are at least two adjacent carbon atoms on a chain which are not attached to hydrogen atoms. When at least two pairs of carbon atoms are empty it is known as a monounsaturated fatty acid. When two or more sets are empty, then it is referred to as a polyunsaturated fatty acid. A good rule of thumb is that the more saturated the fat, the more easily it will stay hard at room temperature.

ESSENTIAL FATTY ACIDS: Essential fatty acids (EFAs) are vital nutritional components that our bodies need for many functions. They are found in the seeds of plants and in the oils of cold-water fish. Essential fatty acids—sometimes referred to as vitamin F— cannot be made by the body; they must be sup-plied in the diet. However, at this time, the government has not officially established a Recommended Daily Intake (RDI). Many factors, including stress, allergies, disease, and a diet high in fried foods, can increase the body’s nutritional need for essential fatty acids.

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RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available

Date: June 24, 2005 05:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available

The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.

Bio-Aligned Antioxidant Support

RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.

Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.

Healthy Heart

Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.

Nourishing the Brain

Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.

Liver Support

Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.

Immune Defense

The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.

Skin & Connective Tissue

Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.

Clear Vision

Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.

Energy Generation

Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.

DNA Protection

DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.

Living Longer, Living Better Strategies for Wellness

• Stop Smoking: Smoking depletes the body of vitamins C and E along with other antioxidants.

Wellness Revolution

Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.

References

Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.

Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf

Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein

Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts

Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric

Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE

Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc

Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf

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Vitanet ®

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How Does CLA Work?

Date: June 22, 2005 09:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does CLA Work?

How Does CLA Work?

How could CLA hinder the growth and development of certain cancers in animals? Scientists have developed some intriguing possibilities, and many of them are related to the theory of antioxidants.

WHAT IS AN ANTIOXIDANT?

Well, one of the ironies of life is that oxygen, so essential to human life, also causes decay. Look at the parts of your car where paint may have pealed away, and you will notice rust, what scientists call oxidation. Molecules of oxygen combine with the iron or chromium on your car and change its chemical alignment to iron oxide or chromium oxide—rust. In a very real sense, the same thing happens to you as you age. Inside your cells, thousands of chemical reactions take place each moment. These reactions break apart the long chains of carbon, oxygen and hydrogen that make up body tissues and combines them in new ways. Some of those combinations cause decay. One example is when a free radical—a single atom of roaming oxygen—attaches itself to something useful, rendering it useless or even dangerous. If a free radical were to change DNA, for example, that could mutate a cell. This free radical process is one way this oxidation occurs, and antioxidants, often called free radical scavengers, attach themselves to the free radicals, blocking their damage. This can help improve life and help to cut the problems of oxidation. Indeed, many see antioxidants as a way of lessening the risks of cancer.

Many people know about important antioxidants, such as ascorbigen (vitamin C), selenium or alpha tocopherol (vitamin E), but nature provides numerous antioxidants. Many exciting ones are emerging, such as proanthocyanidins (often known as pycnogenol), quercetin (common in many fruits) and selenium (a mineral). C LA may be another antioxidant emerging from the research. Dr. Pariza and others found in a 1991 experiment that in the test tube, CLA was effective in battling free radicals. 28 It helped prevent damage to the DNA inside the cells. Pariza says in another paper, “Our hypothesis is that the antioxidant activity of CLA may at least in part explain its anticarcinogenic effect.”29 That would mean that one way CLA prevents cancer is because it blocks these dangerous free radicals. (Other theories about how it fights cancer include breaking down the chemicals that cause cancer into others that don’t .30 All the theories may be true in specific situations, and none might.) But like many other emerging, exciting areas of scientific inquiry, this idea that CLA is an antioxidant has doubters. Researchers J.J. van den Berg, N.E. Cook and D.L. Tribble wanted to see if CLA protected fatty membranes comprised of a substance called palmitoyl-2-linoleoyl phosphatidylcholine (PLPC) from the damage of biologic oxidation. In research published in 1995, they compared CLA’s effect to the wellknown antioxidant vitamin E. While vitamin E protected well, CLA did relatively little. They also found that CLA did not become a mineral chelator, an agent that helps natural minerals become available biologically. They bluntly said, “On the basis of our observations, a role for CLA as an antioxidant does not seem plausible.”31

Another study in 1995, however, showed that CLA can break down into other substances, called feran derivatives, that do act as antioxidants.32 As in all emerging sciences, debates ensue among honest, dedicated researchers. CLA may not, itself, be a antioxidant. Perhaps it acts as antioxidant in only certain situations. Perhaps things that come from CLA act like antioxidants. That is the state of the research today. (Indeed, Dr. Pariza says such debates are common in the field of antioxidants. 33)

What is important to remember is that in numerous animal models, CLA protected against the dangers of many different kinds of cancer in animals, and that, according to scientists, it is one of the most potent cancer-preventing substances of its kind known to science. Whether the cause of this effect was because of CLA or because of some other reason really isn’t that important.

Another thing to remember is that CLA is not a cancer drug. It is something that would be useful in addition to other cancer treatments. It is something to consider to lower your risks and, perhaps, lessen the effects of treatment. It should not be considered a treatment option on its own.

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