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Unlocking the Benefits of Green Tea Extract   
Date:
August 10, 2023 10:43 AM
With the growing awareness about the health benefits of green tea, it comes as no surprise that it has become a popular health supplement. One potent green tea supplement that has continued to maintain attention is Natures Answer brand Green Tea Extract in an Alcohol-Free Liquid Extract. Packed with powerful antioxidants, this supplement can aid in digestion, weight management, and overall well-being. Powerful Antioxidant Antioxidants are substances that inhibit oxidation, a process that can lead to cellular damage. They act as scavengers, helping shield the body from harmful free radicals, which are unstable molecules that can inflict damage to our cells. This is where green tea, and particularly green tea extract, shines. Rich in antioxidants known as polyphenols, green tea plays a significant role in maintaining the body's overall health. Polyphenols, including flavonoids and catechins, are known for their potent antioxidant effects. The most notable catechin in green tea is Epigallocatechin Gallate (EGCG), widely studied for its powerful impact on health. Green tea's antioxidants help neutralize harmful free radicals, reducing oxidative stress, and subsequently lowering the risk of a host of chronic conditions including heart disease, type 2 diabetes, and even certain cancers. Thus, the antioxidants in green tea aren't just important, they're an integral part of a health-conscious lifestyle. Boost Immune System Green tea boosts immunity through its potent bioactive compounds, primarily polyphenols like catechins. These compounds exhibit powerful antioxidant properties, neutralizing harmful free radicals in the body. Additionally, they help increase the body's production of detoxifying enzymes, further enhancing the immune system's efficiency. Green tea also contains a type of catechin called Epigallocatechin Gallate (EGCG), renowned for its immune-boosting properties. EGCG aids in the production of T-cells, the body's first line of defense against infections. Furthermore, green tea fosters beneficial gut bacteria, which play a crucial role in maintaining a robust immune system. Promotes Weight Loss Green tea extract works to accelerate weight loss primarily through its active ingredients, one of which is caffeine. Although not as much as coffee, green tea does contain sufficient caffeine that can aid in fat burning and improving exercise performance. More importantly, it is loaded with potent antioxidants called catechins. The most important of these is Epigallocatechin gallate (EGCG), a substance that can boost metabolism. Studies suggest that the combination of EGCG and caffeine in green tea extract can assist in weight loss by helping the body burn more calories, even at rest, and breaking down more fat cells. Additionally, green tea extract is known to increase fat oxidation and improve insulin sensitivity, both beneficial for weight control. While the effects on each individual can vary, when combined with a balanced diet and regular exercise, green tea extract can indeed support and accelerate weight loss efforts. Impacts Central Nervous System Green tea extract is known to have profound effects on the central nervous system, primarily due to the presence of caffeine and an amino acid called L-theanine. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter in the brain called Adenosine. This increases the firing of neurons and the concentration of neurotransmitters like dopamine and norepinephrine, leading to improved brain function, mood, vigilance, reaction times, and even memory. On the other hand, L-theanine can cross the blood-brain barrier and has been shown to increase the activity of the inhibitory neurotransmitter GABA, which has anti-anxiety effects. It also increases dopamine and the production of alpha waves in the brain. The unique combination of these two compounds in green tea extract is believed to make it an excellent tool for maintaining and enhancing the central nervous system. Improve Mental Efficiency Green tea improves mental efficiency through several biological mechanisms. Primarily, it contains caffeine and L-theanine, two compounds known to enhance brain function. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter called adenosine, which not only increases the firing of neurons but also amplifies the concentration of other neurotransmitters like dopamine and norepinephrine. This results in improved brain function, vigilance, reaction times, memory recall, and mood. On the other hand, L-theanine is an amino acid that can cross the blood-brain barrier and has psychoactive properties. It promotes relaxation without drowsiness and can work synergistically with caffeine to enhance brain function. Furthermore, L-theanine increases the frequency of alpha waves in the brain, which leads to improved creativity and problem-solving abilities. Moreover, green tea is rich in polyphenols and antioxidants, particularly Epigallocatechin Gallate (EGCG), which has protective effects on neurons, potentially lowering the risk of neurodegenerative disorders like Alzheimer's and Parkinson's disease. Hence, regular consumption of green tea or its extract can significantly improve mental efficiency. Promotes Heart Health Natures Answer Green Tea Extract Alcohol-Free Extract can help you maintain healthy cholesterol levels, reduce high blood pressure, and prevent blood clot formation that can lead to heart diseases. The polyphenol and catechin compounds in green tea extract are known to promote the health of the heart by reducing inflammation and improving blood vessels' function. Green tea maintains healthy cholesterol levels by inhibiting the absorption of cholesterol in the digestive tract and aiding in its excretion. This leads to a reduced level of LDL (bad cholesterol) in the bloodstream, while not affecting the levels of HDL (good cholesterol). Green tea extract can also lower blood pressure. The catechins it contains help to dilate blood vessels, improving their function and allowing blood to flow more easily. This can lead to a significant reduction in blood pressure, especially in cases of hypertension. Furthermore, studies have shown that the antioxidants in green tea can prevent the oxidation of LDL cholesterol, a process that contributes to the formation of plaques in arteries and blood clot formation. By preventing this oxidation, green tea extract can reduce the risk of heart diseases and strokes. Lastly, the anti-inflammatory nature of green tea's antioxidants helps in reducing inflammation in blood vessels, a condition that can contribute to heart disease. By reducing inflammation, blood flow improves, and the risk of heart disease decreases. In this way, green tea actively promotes heart health. In conclusion, Natures Answer Green Tea Extract is an all-in-one supplement that can enhance your overall health and well-being in various ways. The antioxidant, anti-inflammatory, and weight management properties of this supplement can do wonders for your physical, neurological, and mental health. Incorporating Natures Answer green tea (alcohol free) liquid extract into your daily routine can help you unlock the multiple benefits that this tea has to offer. So, go ahead, give it a try, and reap the benefits of this powerful supplement!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6585) How Melatonin Can Support a Healthy Sleep Cycle and More 
Date:
May 11, 2022 12:19 PM
Did you know that melatonin is a powerful free radical scavenger? This means that it helps protect the body from damage caused by harmful molecules called radicals. Melatonin is also naturally produced in the pineal gland and is present in high amounts in the GI tract. We will discuss some of the ways that melatonin supports health and wellness. Melatonin and the body Melatonin is a hormone that is produced by the pineal gland in the brain. It is responsible for regulating the body's internal clock, or circadian rhythm. The production of melatonin increases at night, and decreases during the day. This hormone is also available in supplement form, and is often used to treat jet lag or insomnia. When taken as a supplement, melatonin works by resetting the body's internal clock, making it easier to fall asleep and stay asleep. Additionally, melatonin may also help to reduce anxiety and improve mood. As a result, this hormone plays an important role in regulating the body's sleep-wake cycle. How does melatonin support a healthy sleep cycle? Melatonin is a hormone that help regulate the sleep cycle. The production of melatonin is stimulated by darkness and inhibited by light. As a result, melatonin levels typically start to rise in the evening as the sun sets, and they remain high throughout the night. In the morning, light exposure causes melatonin levels to drop, helping to wake us up and start the day. Melatonin supplements can be used to help people who have difficulty sleeping and staying asleep. This hormone helps to reset the body's natural sleep cycle, making it easier to fall asleep and stay asleep. As a result, melatonin can be an effective way to support a healthy sleep cycle. What are some of the other benefits of melatonin? It can help to boost the immune system, protect against cancer, and reduce inflammation. Research suggests that melatonin may also have neuroprotective effects and could be beneficial for people with Alzheimer's disease or Parkinson's disease. Tips for getting a good night's sleep Most people need about seven to eight hours of sleep a day. However, many people find it difficult to get enough rest. There are a number of things you can do to improve your sleep habits. First, create a regular sleep schedule and stick to it as much as possible. Go to bed and wake up at the same time each day, even on weekends. Second, create a relaxing bedtime routine. This might include taking a warm shower, reading a book, or writing in a journal. Third, create a comfortable sleep environment by making sure your bedroom is dark, quiet, and cool. Fourth, avoid caffeine and alcohol before bed. Caffeine can make it difficult to fall asleep and stay asleep, while alcohol can disrupt your sleep cycle. Finally, try not to use electronic devices in bed. The blue light emitted by screens can interfere with your body's natural sleep rhythm and take melatonin. By following these tips, you can improve your chances of getting a good night's sleep. Scientific research Research on melatonin began in the 1950s, and since then, numerous studies have been conducted on its potential health benefits. Some of the most promising research has found that melatonin may help to prevent cancer. In one study, melatonin supplements were found to reduce the risk of breast cancer recurrence by half. Other research has shown that melatonin may help to protect against colon cancer, prostate cancer, and ovarian cancer. Additionally, melatonin has been shown to boost the effectiveness of chemotherapy drugs and radiation therapy. While more research is needed to confirm the exact role of melatonin in cancer prevention, the available evidence suggests that it could play a significant role in protecting against this disease. Therefore, it may be worth considering supplementing with melatonin if you are at high risk for cancer or are undergoing treatment for this disease. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6407) The Amazing Health Benefits of Green Tea
Date:
May 08, 2019 01:32 PM
Green tea is a very versatile health food with many different benefits. Green tea can help regulate your weight and your blood sugar. The caffeine and l-theanine it contains can help improve brain functioning and reduce anxiety symptoms. Green tea bags can be used to repair damage inflicted on your skin by free radicals and UV light. Green tea’s powerful anti-inflammatory effects may even help to reduce the damage to the body and brain from conditions like cancer, Alzheimer’s and Parkinson’s disease. Key Takeaways:
"“Green tea has been a favorite drink of health enthusiasts for decades,” Dr. Ellen Kamhi, Ph.D., author of the”Alternative Medicine Definitive Guide,” tells Newsmax. “It has also been well studied for its health promoting effects on skin. It’s high in compounds called polyphenols which help eliminate free radical damage and rejuvenate aging skin cells." Read more: https://www.newsmax.com/health/health-news/green-tea-health-benefits/2019/03/19/id/907629/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6281) 10 Reasons why vitamin D is essential for your health
Date:
May 07, 2019 04:47 PM
Vitamin D is considered the sunshine vitamin because it is synthesized by the skin when one is exposed to the sun. It is paramount for optimal health. It can only be found in a handful of foods such as fish, mushrooms, eggs, and fortified foods. The sun is the most important source of this vitamin. Many persons tend to spend less time outdoors that is why a third of the population is deficient in vitamin D. Here are some reasons why it is beneficial to take the sun and get this vitamin. One health benefit of vitamin D is that it improves muscle function. Deficiency of this vitamin is linked to loss of muscle mass and strength. Another health benefit is that it lowers the risk of asthma attacks by half. Vitamin D can also help to prevent and treat multiple sclerosis, and protect against Alzheimer’s and parkinson’s disease. Other health benefits are outlined in the article. Key Takeaways:
"These days, however, most of us tend to spend less time outdoors which may explain why more than a third of the world population suffers from low levels of vitamin D." Read more: https://www.naturalnews.com/2019-03-19-10-reasons-why-vitamin-d-is-essential.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6279) Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ...
Date:
April 22, 2019 04:29 PM
Many Coenzyme Q10 products have labels that indicate that their product is better absorbed due to longtime beliefs surrounding ubiquinol (reduced Coenzyme Q10) being hard for the body to absorb. Many brands instead market ubiquinone, which is redox Coenzyme Q10 instead, since studies have been more supportive about this form being easier for the body to absorb. New research, however, is concluding that both of these forms are equal when it comes to the ability to be absorbed through the body. Key Takeaways:
"Marketing terms such as “better absorbed” should be questioned unless the absorption or bioavailability is actually stated. Only when the actual absorption has been verified can the better absorbed product be determined." Read more: https://wholefoodsmagazine.com/columns/vitamin-connection/coenzyme-q10-research-confirms-ubiquinone-and-ubiquinol-are-nearly-equally-absorbed-compounds-the-physical-form-and-companion-ingredients-make-the-bioavailability-and-absorption-difference-in-coenz/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6152) PQQ is effective in combating neurodegeneration that can affect theaging brain
Date:
December 21, 2018 08:53 AM
A nutrient called Pyrroloquinoline quinone (PQQ) has shown potential for combating the degenerative neurological symptoms of Alzheimer’s, according to research published by Life Extension. Mice that were given a PQQ supplement developed smaller deposits of toxic proteins in their brains compared to the mice that did not, and also demonstrated better recall, memory, motor skills and learning relative to the control group. Other research suggests PQQ may help with Parkinson’s symptoms, and improve blood circulation within the brain. Key Takeaways:
"But there are many ways in which a person can reduce their risk of neurodegeneration as they age, like healthy eating." Read more: https://www.naturalnews.com/2018-12-13-pqq-combats-neurodegeneration-that-can-affect-the-aging-brain.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5916) Your depression may be caused by chronic brain inflammation
Date:
November 15, 2018 12:51 PM
Depression is something that a ton of people in the world today suffer from. It is not an easy thing to deal with. However, if you are someone who has it, then you must find how you can cope with it. It may be hard but there is always something that you can do to help yourself. Understanding where depression comes from is difficult as well. However, some doctors say that it can be caused by some brain inflammation. Key Takeaways:
"Chronic inflammation is largely caused by unhealthy lifestyle habits such as poor diet, lack of physical exercise, and inadequate sleep, among others. These behaviors, while seemingly inconsequential initially, fuel the inflammation response long after it stops being helpful." Read more: https://www.naturalnews.com/2018-11-09-your-depression-may-be-caused-by-chronic-brain-inflammation.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5834) Known as the "bliss molecule", anandamide is a natural way to stimulate a sense of happiness
Date:
August 10, 2018 05:53 PM
Anandamide is a natural endocannabinoid produced in your body and found in certain foods that stimulates the same pleasure receptors as psychoactive THC. Anandamide and other endocannabinoids can help protect the brain from stress and damage, and encourage balanced moods and better consolidation of memories. The only two foods with large amounts of anandamide are (famously expensive) black truffles and chocolate, especially cacao powder and nibs, which are less processed. Several other foods, including black pepper, olive oil, grapes, broccoli, spinach and others can also raise your anandamide levels. Key Takeaways:
"The “bliss molecule” is a natural neurotransmitter and endocannabinoid that creates a sense of happiness, an article on Be Brain Fit stated." Read more: https://www.naturalnews.com/2018-08-08-anandamide-is-a-natural-way-to-stimulate-a-sense-of-happiness.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5704) 7 Surprising Uses For CBD Oil That You Never Would Have Guessed
Date:
July 13, 2018 09:54 AM
CBD oil is becoming increasingly more popular for the treatment of anxiety, pain, and numerous other issues. However, it can be used for other reasons too. CBD oil can be used to help you stop smoking. Other also use it to treat acne or to help them attain a higher quality of sleep when they struggle with insomnia.Mandy Moore uses it to numb her feet from high heels usage. It has also found use as a treatment for Parkinson's, Alzheimer's, and more. Key Takeaways:
"Beyond pain or anxiety, there might actually be some brilliant uses for CBD oil that you never would have guessed that you may want to know more about." Read more: https://www.romper.com/p/7-surprising-uses-for-cbd-oil-that-you-never-would-have-guessed-9718263
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5667) 4 Groundbreaking Studies on Cannabis and Disease
Date:
November 17, 2017 07:59 AM
Cannabis is becoming more popular for the treatment of many diseases and ailments. It is becoming legal in more places as well due to studies which show its effectiveness. This talks about four such studies. If you are leery of cannabis this might ease your mind. It is often helpful. Many people swear by it as a treatment. It also doesn't tend to have many negative side effects the way medications can. It is safer. Key Takeaways:
"This study will allow researchers to better understand the potential risks and benefits of cannabis use among veterans with PTSD and aid in cannabis-based decision making among patients and their physicians." Read more: http://www.care2.com/greenliving/4-groundbreaking-studies-on-cannabis-and-disease.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5401) Are gut microbes really a panacea, or just overhyped?
Date:
September 22, 2017 09:14 AM
Gut microbes and their role in physical as well as mental health has received a lot of attention in the past few years. Researchers are claiming that some day probiotic medicines can be taken to combat disease, both mental and physical. his is not just hype. Serious research is being done to learn how these microbes work on the human body with the hopes of creating probiotic like medications someday. Read here about these recent research advances. Key Takeaways:
"The gut microbiome does indeed show huge potential, but the research is still in its infancy, and many of the big questions remain unanswered." Read more: https://www.theguardian.com/commentisfree/2017/sep/07/gut-microbes-panacea-brain-probiotic
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5270) The 8 Most Important CBD Studies Ever Published
Date:
May 28, 2017 04:14 PM
A marijuana advocacy blog has a story listing the eight most significant CBD studies to date. The story states that CBD studies are easier to conduct because the substance does not have psychoactive properties. The studies cover topics such as effectiveness in treating seizures, anti-inflammatory properties, and pain relief. Each discussion is accompanied by a color photo along with an embedded link to the actual study. A brief description of the writer is contained at the end of the feature. There were no comments. Key Takeaways:
"And that’s beneficial because research continues to show the central role CBD plays in the medical benefits of cannabis." Read more: https://www.greenrushdaily.com/2017/05/07/important-cbd-studies/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4717) More ailments could be added to cannabis oil treatment list
Date:
April 27, 2017 04:14 PM
Canon is oils has a great amount of benefits to it but the various parts of beneficial leads that the oil produces in the attainment of its glory is vast. The different types of positive affect that the oil has show in in the treatments of our great advancement in different fields of study is great and growing everyday and the study and production ashows great strides in different fields generating different products and product margins leading to greater growing and growth overall. Key Takeaways:
"Folks with cancer, Crohn’s disease, Lou Gehrig’s disease, mitochondrial disease, multiple sclerosis, Parkinson’s disease, seizure disorders and sickle cell disease can be legally be treated using cannabis oil as of 2015." Read more: http://www.wrdw.com/content/news/More-ailments-could-be-added-to-cannabis-oil-treatment-list--420136993.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4491) Consuming silicon-rich water or foods can purge your body of up to 70% of the of aluminum in your bloodstream
Date:
April 08, 2017 11:44 AM
Despite the fact that aluminum is known to be a dangerous substance, it can be found in a large number of our regular items, for example, prepared sustenance, cookware, immunizations, prescriptions, child items, beauty care products, antiperspirants, sunscreens, cleaning items, tap water, and even noticeable all around we relax. The conclusion that drinking silicon-rich mineral water might be the answer for shield your body and mind from aluminum developments and cerebrum harm. Amid the clinical trials, including both solid people and individuals with Alzheimer illness, and found that drinking around one liter of silicon-rich mineral water each day can accelerate the discharge of aluminum by means of the kidneys and pee by up to 70 percent. Drinking silicon water is a non-intrusive approach to expel more aluminum from the body, something which benefits everybody, including immunized kids and individuals with infections, for example, Alzheimer's, dementia, and Parkinson's. Key Takeaways:
"Today, aluminum is so abundant in our surrounding environment that it is practically impossible to avoid. Therefore, Dr. Exley has dedicated over two decades of his life to researching the effects of aluminum toxicity." Read more: http://www.naturalnews.com/2017-04-04-consuming-silicon-rich-water-or-herbs-can-purge-your-body-of-up-to-70-the-of-aluminum-in-your-bloodstream.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4376) Watch ANOTHER Man with Severe Parkinson’s Take Cannabis Oil to Settle his Tremors
Date:
March 16, 2017 11:14 AM
In considering whether cannabinoids are a suitable therapy for Parkinson's symptoms, the potential benefits must be weighed against the possible side effects. Used in moderation, cannabinoids appear to be relatively well tolerated. Even so, a review of clinical trials involving cannabinoids showed that nearly seven percent of participants discontinued them due to issues such as nausea, dizziness, weakness, mood and behavioral changes, hallucinations and impairment of cognitive (memory/thinking) abilities. [video mp4="//www.healthnutnews.com/watch-another-man-severe-Parkinsons-take-cannabis-oil-settle-tremors/"] Key Takeaways:
"His used just a single drop and his hands afterwards were rock steady and the Dyskinesia left."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4173) Link between dietary restriction, longevity examined
Date:
February 09, 2017 12:59 PM
The link between dietary restriction and longevity has been examined. Research has been done and shows that cutting back on calories can actually expand the life span of roundworms. This is important because it shows that we can enhance our health and not have to put huge dietary restrictions on ourselves. Key Takeaways:
"The life-prolonging effects of dietary restriction, or calorie restriction, occur in just about every animal tested." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3914) New class of hydrogen sulfide donor molecules
Date:
January 16, 2017 10:59 AM
One of the most destructive forces in our bodies is oxidative stress. This causes a breakdown of molecules within the body, which then leads to problems such as heart attacks, cancer, and Alzheimer’s disease. The University of Oregon has just released a study showing that they were able to design organic molecules that can be used to release hydrogen sulfide when oxidative stress triggers it. This compound functions to restore molecular stability within the body. This is just the first step in producing new drugs for treating currently life-threatening conditions. Key Takeaways:
"Oxidative stress damages cells and is tied especially to heart disease and cancer, as well as Alzheimer's and Parkinson's disease." Reference: https://www.sciencedaily.com/releases/2016/12/161230103540.htm
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3789) Low levels of manganese in welding fumes cause neurological problems
Date:
January 10, 2017 10:59 AM
Recently a new study has found that welders that are exposed to airborne manganese at some estimated levels that are under safety standards set by federal law have developed neurological problems. In general the current standards that are set for safety might not be adequate enough to protect welders from the dangers that come with it. Key Takeaways:
""We found that chronic exposure to manganese-containing welding fumes is associated with progressive neurological symptoms such as slow movement and difficulty speaking," said Brad A. Racette, MD, a professor of neurology and the study's senior author." Reference: https://www.sciencedaily.com/releases/2016/12/161228171126.htm
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3764) How Glutathione Reduces Effects Of Parkinson's Disease
Date:
December 10, 2016 02:23 AM
Parkinson's Disease is an incurable chronic and movement disorder that results from the death of neuron cells of the substantia nigra area of the brain. The symptoms associated with this disease worsen as one ages.When the neurons die, they release a chemical called dopamine that is a neurotransmitter that relays messages to movement and coordination centers of the brain. As one ages, the dopamine level produced decreases making it hard for transmission of messages to this part of the brain responsible for movement and coordination. This makes the patient unable to control movement of body parts. Symptoms of Parkinson's Disease:
How To Reduce Effects Of Parkinson's Disease:PD currently has no cure. However, doctors do surgeries and other medical procedures on affected parts of the brain to reduce effects of this disease. Researchers worldwide agree that there could be a breakthrough in the treatment of this chronic disease with the administration of glutathione (GSH) to patients. The supplement works in the following ways: Our bodies naturally produce glutathione which is an antioxidant. Its production however reduces progressively as one ages. Its main role is to fight free radicals which may build up to cause oxidative stress. Patients should thus take the glutathione supplement daily to help them fight this oxidative stress which causes PD. Glutathione also supports mitochondria. This ensures consistent energy production in mitochondria. This energy is useful in the fight of PD. Glutathione makes the brain effectively use dopamine and detoxifies the body. This ensures that heavy metals which may attack the brain are regularly removed from the body. Numerous studies are however still underway to determine how this supplement can be used effectively. Glutathione should not be taken orally as it is broken down in the gut before it can be used in the brain cells.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3609) Did you know that cinnamon can boost intelligence?
Date:
November 01, 2016 06:09 PM
cinnamon has a flavor that you either love or you hate. If you happen to be someone that enjoys the taste, you're in luck! did you know that cinnamon consumption may work to boost your intelligence? The next time someone questions how smart you are, pull out the cinnamon and thank them for noticing! Key Takeaways:
"Scientists at Rush University Medical Center in Chicago found that increased ingestion of cinnamon significantly improved the memory of "poor learning" mice." Reference: //www.naturalnews.com/055813_cinnamon_intelligence_Parkinsons_disease.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3369) Low vitamin D levels linked to Parkinson's and Alzheimer's disease
Date:
October 30, 2016 04:59 PM
Alzheimer’s, Parkinson’s disease, & multiple sclerosis have become more prevalent over the years. Recent neurological studies are showing that these conditions can be prevented by supplementing more vitamin D in the diet. Many people just don’t get enough sunlight to provide the needed amount of vitamin D each day. It has been recommended to get at least 600 to 800 IU of the vitamin per day, but some are suggesting that we may need up to 8,000 IU per day in order to prevent disease, depending on our current health. Key Takeaways:
"Adequate vitamin D blood levels help to ensure protection and support of these crucial systems to prevent the onset and progression of these diseases."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3355) What are the Benefits of Jiaogulan
Date:
July 10, 2014 08:20 PM
What is a jiaogulan
Benefits of jiaogulan Generally, this plant offers numerous health related benefits with minimal side effects. To Begin with its adaptogenic capabilities, not only helps the body to resist the effects of a stressful conditions, but it also promotes the condition known as homeostasis which helps the body to achieve a state of balance through by regulating various and numerous internal body process. To be more specific, the Jiaogulan herb has adaptogen properties that address both the excess output and the deficiency in the body immune and the endocrine systems. Basically, the adaptogens and the saponins in this plant not only aids the body to regulate itself, which is indeed a key factor in the prevention of diseases and defects such as diabetes, stroke, insomnia, cancer, heart attack, hypertension, atherosclerosis, hormonal imbalance as well as prevention of the high blood pressure, aiding in the proper function of the cardiovascular as well as helping to regulate the cholesterol level in the body among many more. Additionally, Jiaogulan has some collective chemical compounds known as gypenosides.These gypenosides compounds offer protection against free radical elements and thus against oxidative stress within the brain, which are known to be the main trigger of the Parkinson disease. Their antioxidant capability improves immunity, reduces the effects of aging and speeds the rate of muscle recovery. This herb also has the capability to release nitric oxide, which helps to relax the body blood vessels, its antioxidant compounds ensures you leave free of the radical compound hence your longevity. If you need to build your body mass, muscles,your strength as well as to reduce fatigue, then this herb will be so suitable for you. Finally, the the Gynostemma also has important minerals, vitamins,amino acid and traces of minerals, which of course is generally essential to the body.Sources 1.//www.jiaogulan.net/benefits.htm: 2.//www.herbslist.net/gynostemma.htm: 3. //getfit.jillianmichaels.com/benefits-jiaogulan-tea-1529.html: 4.//www.livestrong.com/article/283943-what-are-the-health-benefits-of-jiaogulan-tea/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3146) Educative And Informative Details About NADH Supplement And Its Benefits
Date:
May 12, 2014 03:34 AM
What is a NADH
How NADH works Instead, when the foods that provide the body with energy are ingested, they are usually broken down into smaller parts after being absorbed and distributed into various cells. One of the things that are derived after these foods being broken down is acetyl, which is a two-carbon molecule. Enzymes are the primary components that break the foods into acetyl. However, enzymes require coenzymes to break these foods properly and extract the energy from acetyl. This makes NADH is an important coenzyme, which extracts energy from reactions between oxygen and acetyl. This coenzyme also helps in transforming tyrosine, which is an amino acid into dopamine, which is a brain chemical. Benefits of NADH One of the primary benefits of NADH supplement is that the brain chemical it helps to produce known as dopamine helps in improving various brain functions. Some of these functions which this chemical affects include; concentration, mood, muscle movement, sexual drive and energy. It also helps in athletic performance, slowing aging process, Parkinson's disease, depression and Alzheimer's disease. This supplement is also helpful on people with chronic fatigue syndrome. This is achieved through helping patients reduce anxiety and reduce heart rate. Consequently, the patient is able to relax and allow the body to function normally. Therefore, NADH supplement is helpful and has many benefits if it is used properly. Sources 1. //www.nadhsupplement.co.uk/ 2. //www.raysahelian.com/nadh.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3118) Why Eat Gluten Free
Date:
April 17, 2014 04:48 AM
What is gluten
Check out these insights why you and your family should take gluten free diet: Lose weight Recent research has revealed that gluten is related with obesity and weight gain. Gluten is a super carbohydrate and is quickly converted to blood sugar than any carb food. This results in glucose being released into the bloodstream. Insulin supports your body in converting glucose to fat causing a lot of fat deposits. Ward off diseases Increased gluten consumption has caused a great rise in several diseases such as ADHD, heart diseases, diabetes and autism. Gluten and disease relationships are still under research but meanwhile it is safer to reduce gluten intake within your family members. Improves mental health Different researches have associated Celiac disease with issues such as dementia and nervous system problems. Over the last 60 years, there have been some studies relating patients with Schizophrenia and gluten consumption. Regain balance You can find gluten everywhere in pizza, bread, salad dressings, spices, ketchup and cosmetics. An average American person can consume about 130 pounds of wheat every year which makes 70 percent of our carb intake. Quick recovery If you are suffering from diseases such as Osteoporosis or Parkinson's disease, Rheumatoid Arthritis then taking non gluten diet is the best way of getting healthier quicker. Certain research has shown that eating gluten free diet helps you to take less recovery time when you use along with their treatments. You can give a try by eliminating gluten and check any change in your healthy condition. Several gluten free food choices are available. Source
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3093) What IS NADH And Why Would I Want To Take It Daily?
Date:
January 10, 2014 05:20 PM
What IS NADH And Why Would I Want To Take It Daily?
But there are some individuals who have a lesser production of this chemical and because of that medicine providers have created NADH supplements. What are the uses of NADH? NADH supplements are effective for providing focus, improved concentration, and mental clarity as well as upgraded memory skills. For this reason some people are taking it daily, people who have Alzheimer’s, for example are given this drug. Not only that people also use NADH to improve their energy production, athletes use it to increase their endurance, while others are using this supplement to cure their chronic fatigue. Other uses of NADH Will include treatment for blood pressure, it can also reduce cholesterol. Some clinical studies have revealed that is also effective for curing signs of depression as well as Parkinson disease. It is also recommended for people suffering from liver and hormone problems, it works by strengthening the immune system. Individuals who have AIDS and are currently taking a drug called zidovudine or AZT also use NADH to combat the side effects of the drug. While it is used for complex problems, other people just simply use it to relieve symptoms of jet lag. Why do some people prefer to use NADH supplements? NADH is said to be safer than other supplements in the market, it is also safer to use compared with carbonated drinks and energy drinks. It provides extra energy for people to use it, it helps people become alert. This is perfect for individuals who want to maintain increase their day-to-day energy level. Single mothers have reported satisfaction over this drug, with only 10 mg of this supplement they are already given extra energy to take care of their kids. NADH also works as a way for people to regain youth and vitality, the extra energy produced in the body inspires people to do more. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2959) The Facts About Herb Dopa Mucuna
Date:
December 15, 2013 05:17 PM
What is Herb Dopa Mucuna?  Dopa Mucuna has become used as an aphrodisiac. Which is still used to raise and help libido in both women and men. However it's an alternative treatment peculiarity now is extremely popular used as it provides potential and valuable results in managing Parkinson along with conditions. Pots include seeds called velvet beans or mucuna beans, these are glowing brown or black. Dopa Mucuna is generally be able to recover soil fertility and decrease weed infestation. In society medicine seeds can be used healing different conditions and disease. Mucuna beans have been used as a coffee alternate (ground and roasted) in Brazil, Central America, and other countries. The primary acts of the plant are following :
You've surely would not heard about L-Dopa, except if you are associated with somebody who carries body builder or Parkinson's disease, you might not be familiar with about it. L-Dopa is a precursor to dopamine. The seeds of Mucuna bean is rich in lipids, protein, ash, dietary fiber, minerals, and carbohydrates. Moreover they are very high in sterols, alkaloids, and saponins. Mucuna seeds (along with the seeds of every Mucuna varieties) include high level of L-dopa is an immediate precursor of the neurotransmitter dopamine. How does it works? Low dopamine ranges are related to psychosis, addiction, schizophrenia, depression, and Attention Deficit Disorder. Because dopamine itself is unable to move the blood-brain barrier, it is transferred in a precursor condition is an outline that causes the brain to generate dopamine. L-Dopa is simply like a precursor. L-Dopa is located to work in improving concentrate, relieving depressive disorders, and managing Parkinson's Disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2923) All that you may need to know about antioxidants
Date:
November 05, 2013 10:00 PM
Oxidants are elements whose main role is to protect your cells from the harmful effects of free radicals. Free radicals, on their part, are molecules that may be produced by the body when it breaks down food. These molecules may also be produced when your body is exposed to environmental factors like tobacco smoking and radiation. It is worth noting that free radicals have the ability of wrecking damage to cells and causing such diseases as cancers and heart complications. Over the years, studies have consistently revealed that diets high in antioxidants are essential in preventing diseases like Parkinson’s disease, Alzheimer’s disease and cardiovascular diseases. Main Source of Antioxidant The main source of antioxidants is fruits and vegetables. Amazingly, all foods rich in antioxidants are high in fiber, low fat, and are also excellent sources of important vitamins and minerals. It is also important to add that fruits and vegetables rich in antioxidants have bright colors, including purple, yellow, red and orange. Type of Antioxidant The five main types of antioxidants are beta carotene, vitamin C, vitamin E, Zinc, and selenium. Others are lucopene and lutein. Beta-carotene (and other carotenoids), can be derived from a long list of fruits and vegetables. Some of these are asparagus, apricot, broccoli, water melon, sweet potato, kale, mango, turnip and peaches. Vitamin C, as a major and critical antioxidant, can be obtained from kiwi, broccoli, honeydew, kale, orange, papaya, nectarines, strawberries, and snow peas among others. Vitamin E, another major vitamin antioxidant, can be derived from spinach, red peppers, sunflower seeds, papaya, pumpkin and carrots among others. Zinc and selenium are other antioxidants that are essential in maintaining overall body health and boosting the immune system. Common sources of zinc include red meat, poultry, oysters, dairy products, and whole grain foods. Selenium, on the other hand, can be obtained from foods such as tuna, nuts, whole grains, and beef. Fact About Antioxidant The most important fact to realize is that popular sources of antioxidants are fruits and vegetables. Where possible, these foods should be eaten raw or steamed. Boiling will do more harm than good. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2878) How Does Creatine Boost Muscle Strength?
Date:
October 28, 2013 11:13 PM
How Does Creatine Boost Muscle Strength?
What Creatine Can Do?
Many young athletes utilize creatine supplements as part of their muscle building routines. Although there have been varied responses to these diet supplements creatine continues to thrive on the market as a sports and health vitamin. Other uses of it include lowering triglycerides in the body as well as homocysteine both of which play a role in heart attacks and strokes. Creatine also promotes better endurance and muscle strength among patients with chronic obstructive pulmonary disease, Parkinson's disease and Muscular Dystrophy. Clinical trials are still under way. Creatine, like all other medications and supplements may cause some adverse effects. It is important that you consult a health service provider or pharmacist before initiating the use of the supplement. The common side effects of Creatine include muscle cramps, weight gain, muscle strain, abdominal discomfort, changes in bowel movements, dizziness as well as liver and kidney dysfunction. This is due to the fact that this protein is metabolized in the liver and the kidney.
Taking Creatine
Creatine should be taken in the recommended dose. Taking more than the recommended dosage can result to severe adverse events such as Rhabdomyolysis which is the medical term for the breakdown of muscles, the components released after massive muscle cell death can damage the kidney and lead to kidney failure. The recommended dose for adults is 2g daily. Using creatine for prolonged periods may eventually lower your body's production of creatine and may lessen its effects. When used judiciously and properly you can benefit from the positive effects of Creatine.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2862) CoQ10: What You Ought to Know about This Substance?
Date:
March 26, 2013 12:27 PM
Coenzyme Q10 or simply CoQ10 is a substance naturally present not only in a human's body but as well as with the other mammals. It plays a vital role in the production of energy. Back in the year 1957, Dr. Frederick Crane successfully used the mitochondria from the cells of a beef heart in order to locate Coenzyme Q10. But the truth of the matter is that, the substance is also present in human mitochondria. Basically, this substance has antioxidant properties which are highly beneficial in protecting the body against the free radicals present in the environment. Below are some relevant details you ought to know about this substance. Here they are: CoQ10 in Kreb's Cycle
There are a number of chemicals that the body needs to induce metabolism and one of those chemicals is CoQ10. The Kerb's Cycle is the body's mechanism to convert certain enzymes into energy. In order to achieve that, the body needs CoQ10 to facilitate the conversion of the enzymes in energy production. CoQ10 is fundamental in the Kerb's Cycle as it supports the electron transport chain in which the oxidative phosphorylation of the ADP (adenosine diphosphate) into ATP (andenosine triphosphate) needs electrons that are exactly delivered where they must be. Without CoQ10, the entire Kerb's Cycle process would certainly fail. The mitochondria of every power cells synthesize CoQ10 so the substance is present in almost all the body parts. However, the heart consumes the most CoQ10 for the reason that it has the most number of mitochondria and it keeps on working even while the body is at rest. CoQ10 Deficiency If the Kerb's Cycle fails due to CoQ10 deficiency, the person will feel exhausted and weak. But aside from that, there are other conditions that are often associated with the deficiency such as cardiovascular related diseases, Parkinson's disease and gum disease. Conversely, it doesn't necessarily mean that those diseases are brought about by CoQ10 deficiency. CoQ10 Dietary Sources The main sources of CoQ10 include fish oil, whole grains and organ meats. With a balance diet, people can get sufficient amount of coenzyme Q10. CoQ10 Supplements Aging is an inevitable process and it can affect the synthesis of CoQ10. As humans grow older, the production of the coenzyme Q10 gradually decreases. It was mentioned earlier some of the foods that are incredibly beneficial in maintaining ample amount of CoQ10 in the body. But people who do not really include those foods in their diet should not worry for there are now food supplements that contain CoQ10. Some medications like cholesterol meds can prevent the body from using CoQ10, this is when it is essential for one to take a supplement. Fortunately, with the advent of medical researches and innovative technology in drug manufacturing, CoQ10 can now be ingested into one single tablet, soft gel capsule, hard shell capsule or an oral spray. CoQ10 is a fat-soluble substance so taking it along with foods is highly encouraged. Who Takes CoQ10 Supplement? Children under 18 years old are not allowed to take CoQ10 supplements unless prescribed by the doctor. For adults at the age of 19 or older, the recommended dosage in 30 - 600 mg daily. Higher dosage may be taken for special conditions.
Humans need energy in order to carry out all the tasks. Therefore, CoQ10 must be taken daily, whether from foods or supplements, so the body has the energy to move. Have you had your CoQ10 Today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2834) What Are The Health Benefits Of The Amino Acid Glutathione?
Date:
January 30, 2013 12:33 PM
Glutathione is a naturally occurring substance produced by the liver that acts as a very good antioxidant. Apart from being produced in the body, glutathione is also found in some fruits and vegetables, and also detoxifies and boosts the human immune system. Glutathione is a very exciting and important discovery, as it can do all this, and much more. Experts who have been researching glutathione over the years have found out that it can also treat and repair the damage caused to the body by various factors like pollution, radiation, poor diet, stress, drugs, aging, burns, injury, trauma and infection. Glutathione is found in almost every cell of the body, and acts as a very important antioxidant. It is also found in fresh fruits and vegetables. Anyone with a decent diet should not have to worry about not having enough glutathione in their system. What is it that glutathione does for your body, anyway? Well, to put it simply, glutathione helps keep your cells functioning properly. It also assists the liver in freeing the body of foreign agents like chemicals and pollutants. You might dismiss glutathione as not being of much importance, but its actual role comes into effect when you become severely ill. Not enough glutathione in your body can deteriorate chances of recovery, as it is essential in keeping your cells together and in good condition. There are oral glutathione supplements available for people who don't have enough of it in their body. It has many health benefits like fighting against various diseases and aging. Some of the diseases where glutathione has been proved to effectively act include high blood pressure, cataracts, Parkinson's disease, cancer, male infertility and Alzheimer's disease. It is thus evident how beneficial glutathione is for the human body. Research is being done to explore the possibility of glutathione treating cancer, and some progress has been obtained. If we can successfully treat cancer with this powerful antioxidant, it will be a medical miracle.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2821) Can Resveratrol Help Fight DNA Damage?
Date:
January 21, 2013 01:32 PM
How resveratrol helps in fighting DNA damage Resveratrol is a naturally occurring antioxidant produced by plants to protect them against attacks by predators such insects, bacteria or fungi. This antioxidant which has been the subject of several scientific studies is usually found in large quantities in grape skin or red wine. Although the body can function without it which means that you can not be termed as deficient of this nutrient, the compound is known to have immense health benefits. Scientists claim that human beings have not yet fully discovered the real benefits that can be derived from this antioxidant. Scientists have demonstrated that Resveratrol is quite effective in fighting DNA damage which is responsible for aging as well as disorders that are associated with aging including Parkinson's and Alzheimer's disease. Cell degeneration in vital organs is usually linked to certain factors. An important factor that causes cell loss is the presence of reactive oxygen species (ROS) by mitochondria in the cell which is responsible for cell death and DNA damage. Preventing mitochondria turnover and bio-genesis guards against oxidative mitochondria thus promoting healthy aging.
Cell degeneration has been effectively controlled by using a diet that is low in calories so as to increase mitochondria biogenesis. Adding resveratrol to your diet has the same effect since this antioxidant mimics dietary restriction thus delaying diseases related to aging. The compound has been known to stall the aging process by acting as sirtuin activator. It is also responsible for various effects on fat cells which alter fat mass by acting on cell viability and adipogenesis in mature preadipocytes. Laboratory tests have demonstrated that this compound stimulates bio-genesis which helps in delivering immense health-related benefits in mice. The antioxidant fights off cancer which occurs when there is cell damage during cell division. The compound stops cell division in order to allow enzymes repair damaged genes .It also prevents carcinogenic metabolism, a common cause of DNA damage.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2814) Can Glutathione Taken Orally Be Effective?
Date:
December 28, 2012 04:12 PM
One of the main antioxidant found in the human body is glutathione. The chemical nature of it is made up of three amino acids together bound with tripeptide bonds. The many functions of glutathione in human body include gene expressions, DNA synthesis, protein synthesis, etc. It has been noted that deficiency of this chemical in human body gives rise to diseases and problems like Parkinson's diseases, AIDS, epilepsy, sepsis, Alzheimer's disease, cardiovascular troubles, trauma, Schizophrenia and many others. The amino acid that is extracted from the protein containing food consumed by an individual helps in the formation of glutathione in the body itself. Many medical personalities might suggest the consumption of oral glutathione pills by those who have glutathione deficiency. It must however be noted that the answer to the question can glutathione taken orally be effective is a widely debated topic. Most of the recent medical tests and experiments suggest that although no forms of side effects are caused by oral consumption of this chemical as pills, but effectiveness of the medicine is not 100%. The chemicals and organic supplements present in glutathione are not 100% absorbed by the body when it is taken orally. Without intravenous administration, this chemical would never provide the required results in maintaining a healthy body. The glutathione, when taken down orally, is partly broken in the digestive canal, especially in the small intestines through the enzymes that are present. Hence most of the benefits of this chemical would be lost adding to the cellular toxicity of the body if consumed orally. Most doctors and medical professionals suggest that instead of taking glutathione orally as pills, one should have food that is protein rich. Consumption of protein rich food, especially protein shakes, in turn, adds to the intravenous glutathione production which is best suited for the body. Consuming NAC can help boost glutathione levels as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2789) Lion's Mane Mushroom A Nerve Stimulant?
Date:
December 21, 2012 12:50 PM
Natural sources of nutrition and medication are the only secret to live a energetic, cheerful and long life. Still, the modern day pharmaceutical industry stands in front of this trend as it has to make money by extracting the natural ingredients and selling them back to people. Ancient herbalists had done enough research in finding out medicinal properties within our surroundings. Mushrooms are one of these potent fungus and such a promising fungus is Lion's Mane Mushroom. It is identified by the botanical name Hericium erinaceus. One Beneficial role is in benefiting the nervous system. Our body secrets a nerve stimulating factor, known as NGF; standing for nerve growth factor. It is responsible for new nerve production. Lion's Mane Mushroom does the same thing (by stimulating NGF secretion) because it heals neurological disorders. Terrific disorders like Parkinson's disease can be managed with the intake of this mushroom. Children who are given this mushroom with their meals are seen to be more active mentally than any other normal child. They also adapt, accommodate, improvise and decide faster even under stress. As far as other additional benefits are concerned, Lion's Mane Mushroom boosts the immune system. This is a common property of mushrooms though. So, if you are thinking of adding mushroom dishes to your meals or supply your family with mushroom extracts, that's a smart idea. As these ancient treatment techniques aren't easily accepted by people and benefits of mushrooms are not discussed quite often in public, people don't get to know how powerful & medicinal mushrooms can be. Who knows, few medicinal properties of mushrooms might not have been identified yet? Few more benefits of Lion's Mane:
Digestive system functions better. Just get started with this healthy fungus cause you might not want to miss seeing yourself healthy and active till death.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2765) vitamin B-6
Date:
November 17, 2012 11:58 AM
Vitamin B-6 was discovered by Paul Grorgy in 1930 when doing nutritional studies. He discovered the substance was able to cure a certain skin disease when he tested it in rats. Vitamin B-6 exists in three forms namely pyridoxine, pyridoxamine and pyridoxal. These three are precursors of PLP (pyridoxal 5-phosphate). PLP plays an important role as a cofactor for most enzymes in the body. Vitamin B-6 has many health benefits. To begin with, it helps maintain a healthy heart. It prevents the formation of a substance, homocysteine, which damages the lining of blood vessels resulting to the building up of plaque. This happens when the body attempts to repair the damage. It prevents the buildup, reducing chances of a myocardial infarction. It lowers blood pressure, prevents platelet aggregation and it also lowers levels of cholesterol in the body. Vitamin B-6 from supplements or diets reduces the chances of having Parkinson's disease. In women, it strengthens their immune system and it also promotes proper hormone balance in case of any fluctuations. Vitamin B-6 deficiency exposes one to the carpal tunnel syndrome. It is a disorder that is characterized by a burning or tingling sensation and pain that is felt on the wrist or hand after being strained repetitively. It also causes numbness, loss of strength in hands/ fingers, diminished coordination and swelling. Studies have indicated that increased levels of vitamin B-6, from diets or supplements, reduce symptoms of carpal tunnel syndrome. Toxic potential in grams per day. Vitamin B-6 however becomes toxic if taken in excess. It does not relieve the symptoms immediately. Sometimes it takes up to six weeks before noticing any relief. Those suffering from this syndrome should take fifty milligrams of vitamin B-6 twice or thrice daily. You should never take more than two hundred milligrams of vitamin B-6unless you have been recommended to do so by a doctor.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2718) Benefits Of Bacopa Leaf Extract?
Date:
October 15, 2012 11:30 PM
Bacopa Leaves Bacopa, a medicinal herb, is commonly found in marshy locations in India. Ayurvedic health practitioners use the stems and leaves of bacopa for the preparation of extracts, which is an ayurvedic medicine. In India, the bacopa leaf extract is used for curing a number of diseases for the past 1,500 years. Bacopa is also called brahmi, sambrani chettu, water hyssop, etc. The bacopa leaf extract is highly effective for treating mental problems, epilepsy, asthma, etc. It is also useful for getting relief from depression, anxiety, systolyc blood pressure, palpitation, insomnia, nervousness, memory span, mental fatigue, etc. Bacopa Leaf Extract and Dementia Studies show that bacopa leaf extract is highly effective for people with dementia. These patients experience memory problems, impaired movement, difficulty to speak, etc. Bacopa leaf extract is effective for improving cognitive and neurological functions, and memory. Bacopa Leaf Extract and Parkinson's Disease As per the findings of University of Maryland Medical Center, bacopa leaf extract can be used for treating people with Parkinson's disease. This disease mainly affects chemicals in your brain. Therefore, it creates problems such as depression, cognitive impairment, etc. By improving the blood circulation to the brain, bacopa leaf extract helps to enhance cognitive function, neurological function and mood.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2688) st johns wort and depression
Date:
October 10, 2012 12:10 PM
St. John's Wort St. John's Wort, also scientifically known as hypericum perforatum, or Klamath Weed, is a herb with yellow flowers. It has numerous composition of strong compounds like hypericin and hyperforin thathave shown evidence of antibacterial, antidepressant, anti-inflammatory, anti-viral and antioxidant properties. St John Wort can be used to treat mild session of anxiety depression and mood swings, the hyperforin chemical found in it, elevates the level of the neurotransmitters (dopamine, serotonin) that relay information in between cell and play a vital role in the nervous system. The herb has the ability to inhibit chemical associated with anxiety and depression and thus induce a sense of wellbeing and help moderate depression, anxiety, mood swings, chronic fatigue and low energy level. Other benefit of the St John Wort is that it can help treat hangover and alcoholism; it also helps prevent the risk of getting Parkinson disease. It antibiotic and anti-viral properties can help treat congested sinus or a chronic cough its antibacterial and analgesic propertied help to treat wounds and burn.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2684) The Health benefits of P-5-P
Date:
July 20, 2012 07:51 AM
P-5-P or Pyridoxal-5-phosphate P-5-P or the most commonly called Pyridoxal-5-phosphate is known to be the most active form of the Vitamin B6. This is known to be converted from organic compounds pyridoxal, pyridoxine and pyridoxamine. The Vitamin P-5-P is a coenzyme which support several other enzymes in the body which play a important role in biosynthesis. This also makes optimum use of the vitamin B6 by improving the body metabolism and many other biological process as well. The vitamin B6 traditionally comes in the form of pyridoxine hydrochloride which the body finds difficult to synthesize in its existing state. Hence, this pyridoxine hydrochloride is processed and is formed as Pyridoxal-5-phosphate to help the body to use the vitamin B6 effectively. There are a lot of benefits of the vitamin P-5-P Let us have a look at some of them. Pyridoxal-5-phosphate uses the information from the genes ad helps to produce proteins.P-5-P is also helpful in the formation of hemoglobin, histamine and neurotransmitters and is also helpful in the metabolism of amino acids, fats and glucose.Pyridoxal-5-phosphate also helps in the conversion of dopa which is a useful substance used in the treatment of Parkinson's disease. Dopa is converted to dopamine which is a neurotransmitter which is produced in the brain and is released by the hypothalamus. Food Source The P5P is also helpful in the utilization of the food sources for the formation of energy and also helps in the easy release of glycogen which is the stored energy.P5P also converts glutamate into GABA which is gamma amino butyric acid which is again a neurotransmitter which is known to be found in the mammals. This is found in their central nervous system.The Pyridoxal-5-phosphate also helpful in the process of decarboxylation which is the conversion of histidine to histamine. This also converts SAM-e to propylamine which is known to be a precursor of polyamines.The Vitamin P5P is also responsible to lower the homocystenie levels which are caused by the intake of high amounts of methionine.The Vitamin Pyridoxal-5-phosphate helps in the treatment of irregular heartbeat , which is a condition termed as arrhythmia.This plays a important role in the treatment of myocardial infections. This prevents the blood platelets from sticking to each other which usually causes blood clots.The enzymes produced by the Pyridoxal-5-phosphate also helps in the formation of different kinds of amino acid reactions which keeps the carbon ions stable. This process is very important in the metabolism of the cells.The P5P also helps in the metabolism of the amino acids. Here it helps in converting methionine to cysteine and also converts tryptophan to niacin.Pyridoxal-5-phosphate also plays a vital role in the formation of glucose. This process is known as gluconeogenesis.This also acts a important co-enzyme in the process of glycogenolysis which happens in the liver and muscles and this is known to be a reaction which occurs due to presence of glycogen.The P5P also helps in the formation of antibodies and also assists in the process of hemoglobin synthesis as well. To keep it simpler, the vitamin P5P performs many functions which is very beneficial to the whole human body. The P5P deficiency can also happen in many individuals and even such symptoms are hard to identify. Any person suffering from the P5P deficiency will have symptoms like muscle weakness, irritability or depression. Consulting a physician and taking necessary supplements will help to overcome the P5P deficiency.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2668) What Is Glutathione Good For?
Date:
April 14, 2012 08:03 AM
What is Glutathione? Glutathione (GSH)is a tripeptide derived from non-proteinaceous amino acids. Contains apeptide bond between the group unusual amino of the cysteine group and the carboxylside chain of glutamate. Glutathione, an antioxidant, helps protect cells from reactive species of oxygen such as free radicals and peroxides. Glutathione is nucleophilic at sulfuracceptors and conjugated electrophilic attack poisonous. Groups thiolare maintained in a reduced state to a concentration of about ~ 5 mM in animal cells. Indeed, glutathione reduces any link disulfideformed with in proteins cytoplasmic cysteines by acting as a donor of electrons.In the process, glutathione is converted to its oxidized form glutathione disulfide (GSSG). Glutathione is found almost exclusively in its reduced form, since the enzyme that turns its oxidized form, glutathione reductase,is constitutively active and inducible to oxidative stress.In fact, the ratio of reduced glutathione to oxidized glutathione in cells is often used scientifically as a measure of cellular toxicity. H2O2+ GSSG + 2 ------- 2GSH H2O.
Advantages of the Glutathione Before discussing the benefits of L-Glutathione, let's first talk a little about the nutrient. Glutathione is an antioxidant enzyme dominant which is soluble in water.It is absorbed mainly in the liver.It helps fight against free radical damage.The free radical damage is harmful relatives. Glutathione is involved in a variety of other functions in the body. The function of Glutathione - Benefits of Glutathione Glutathione works in DNA synthesis and repair, protein and prostaglandin synthesis, and amino acid transport.It helps in the metabolism of carcinogens and toxins.Immune system is improved through the use of Glutathione, and contributes to the prevention of cellular oxidative damage, and activation of enzymes. Glutathione also helps and maintains the functions of other antioxidants. Glutathione deficiency There is the possibility of a deficiency of glutathione. It usually occurs during aging.For example, it is seen in macular degeneration related to age, diabetes, and lung and gastrointestinal diseases. It may be the cause of pre-eclampsia, Parkinson's, AIDS and other neurodegenerative diseases. Where to get Glutathione Some sources of glutathione include fruits such as tomatoes, watermelon, grapefruit, oranges, peaches and cantaloupe.It is found in vegetables such as avocados, potatoes, spinach, okra, acorn squash, and asparagus.It is found in most meats as well. Other sources of vegetables such as broccoli, cabbage, Brussels sprouts, cauliflower, kale, parsley, and not only provide GSH - glutathione peroxidase, but it also stimulates the body to make more BA.Since cooking destroys much of glutathione, you will get more to eat raw or steamed vegetables for the best benefits of Glutathione. Reduced glutathione is in a supplementation that we personally use a company called source naturals a Natural Product meeting the above requirements.The nutrient content in their signature product - Total Balance.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2633) The Major Health Benefits Of Hemp
Date:
April 06, 2012 07:47 AM
Hemp Protein Hemp is the only food with the largest amount of protein available on earth. It is easily digestible and it is the only food with a wide range of proteins. These include important fatty acids and amino acids. It is the only food that supplies the human body with all dietary needs at once. Thus, it is the only food that is capable of sustaining human life alone without other nutritional supplements. Apart from being a good source of proteins, hemp supplies the body with important minerals and vitamins. However, the most important component of this food is the essential fatty acids. These include the alpha-linolenic (omega 3) and linoleic acids (omega 6). These two categories of fat are important in the body because human body is not capable of manufacturing them. Therefore, they have to be consumed in the daily meals. The ratio of omega 6 to omega 3 in hemp is 3:1. This is close to the 4.0 on average as the optimum recommendation of the world health organization for a human diet. It plays an important role in various organs of the body including: Heart health Hemp has important nutrients are that are essential for the good health of the human heart. These are the essential fatty acids which play a very important role in ensuring the health of the heart. Several studies have revealed that substituting saturated fats with healthy polyunsaturated reduced risk of cardiac arrest. Such fats are found in hemp and are important in preventing sudden cardiac arrhythmia. They also reduce levels of cholesterol in the blood. Hemp has important fats that also decrease build-up of cellular in the arteries. This is very important as it is associated with a condition known as atherosclerosis. Phytosterol contained in hemp plays an important role in reducing cholesterol in the blood by about ten percent. Brain health Human brain has a large portion that includes essential fat acids. Since hemp supplies the body with these fats, it becomes essential for brain health. It is also vital for proper memory function. Diseases such as Parkinson's and Alzheimer's are preventable with consumption of hemp. The Omega 3 and omega 6 fatty acids also help in delaying or reducing neurological effects that come with these diseases. This improves the kind of life led by individuals with such diseases. Skin health Essential fatty acids play an important role in ensuring healthy skin. Perhaps, this is why hemp seed has been used as an ingredient in various cosmetic products. The Lipids allow the acids to permeate via the skin. Hemp component in the cosmetic products help to nourish the skin directly. Hemp is also very beneficial to people with psoriasis and eczema skin conditions. These are just the major benefits of hemp in the human body. Others include increasing of metabolic rate and energy levels, improving immunity and organic function, among others. Hemp is also crucial in the prevention of degenerative diseases and this proves why it is crucial for positive human health. This food provides a lasting solution to various health complications and you may as well try it and enjoy its benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2628) What Is L-Carnosine And What Does It Do?
Date:
March 30, 2012 08:28 AM
What Is L-Carnosine L-Carnosine is basically a combination of 2 vital amino acids-L-histidine and beta-alanine. It is naturally present in the body, mainly in the muscle, and in many animals too. Carnosine can be broken down easily into the two amino acids, but it is good to know that these amino acids work much better when combined to form L-Carnosine. L-Carnosine has the remarkable ability to revitalize, that is, to make older cells younger and lengthen their life cycle. This compound is commercially available and is the only one that has the rare and distinctive ability to rejuvenate cells. What does L-Carnosine do? In simple language, L-carnosine is able to transform itself into so many compounds with each performing or enhancing a number of crucial body functions such as: May bind to dangerous metal compounds to make them inactive. Turning the resultant metal compound/carnosine into useful antioxidants which in turn can be anti-ulcer agents Protecting and stabilizing cell membranes, keeping cells safe from dangerous free radicals Protecting healthy cells from damage caused by radiation Fighting allergies Enhances blood flow to the brain Acts like a neurotransmitter, helping messages move from one nerve to the other. This helps fight dementia, as in Alzheimer's disease and Parkinson's disease, and boost memory. Blocks guanylate cyclase activation, an enzyme associated with cancer, migraine, asthma, and septic shock. Special derivatives of carnosine can help get rid of the accumulation of sugar compounds and abnormal protein in the eye. A variety of these compounds may cause glaucoma, cataracts, and macular degeneration. Carnosine works like a catalyst to boost the work of so many other compounds and nutrients. Benefits of using L-carnosine Although L-carnosine benefits haven't been extensively researched, according to initial studies it may help in: Dealing with complications related to cataracts, diabetes, neuropathy, and kidney failure. It may also help in slowing down aging in skin, minimizing wrinkles as well as breakdown of elasticity in skin. It can help to prevent joint inflammation, atherosclerosis, and formation of cataract. Carnosine has been known to prevent and reduce cell damage occasioned by beta amyloid-the substance found in Alzheimer's patent's brain. Additionally, carnosine appears able to help get rid of the helicobacter pylori bacterium, the organism associated with stomach cancer and peptic cancer. Therefore, it can significantly help protect and heal both peptic and gastric ulcers. Other possible L-carnosine benefits Increase muscle endurance and strength Improves heart function Speeds healing of wound A powerful antioxidant that can deal with even the worst free radicals Reduces inflammation and boosts immunity It helps pull out or chelate some heavy metals from your body May help autistic children Act as anti-cancer agent in the body Stabilizes cell membranes and slows down lipid peroxidation to protect the process of aging of the brain L-carnosine can help in preventing or even treating age-related conditions like: Cell aging/cellular senescence Neurological degeneration Cross-linking of eye lens Build up of damaged proteins Brain circulatory deficit Muscle atrophy Cross-linking of collagen in the skin DNA chromosome damage LDL cholesterol oxidation Formation of AGEs i.e. advanced glycation end-products. What is stopping you from taking L-Carnosine today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2623) What Makes Ubiquinol The Best Form Of COQ10?
Date:
March 08, 2012 11:48 PM
Benefits of Ubiquinol Ubiquinol is an active antioxidant form of CoQ10. It is pre-converted and ready-to-use diet supplement. Hence, it is easily absorbed and utilized by the body. Research studies show that ubiquinol has proved to be much more effective than ubiquinone and has all vital health benefits as CoQ10. Ubiquinol is the next generation supplement which provides support for a healthy body and mind. It helps you to live a healthy life by raising your CoQ10 plasma level. It also plays an important role in production of energy levels. Moreover, it protects the cells of the body from oxidative kind of stress which can eventually damage proteins, DNA, and lipids. Benefits of Ubiquinol: Cardiovascular health: Clinical studies show that ubiquinol improves the overall cardiovascular health. Cardiac patients who have been taking high dosages of statins like Lipitor, Zocor, etc for a long period of time have decreased levels of coenzyme Q10 as these statins inhibit the body's production level of coenzyme Q10. The low levels of CoQ10 in the body can result in cardiomyalgia, fibromyalgia, atherosclerosis, etc. Thus, if these patients take ubiquinol which is an antioxidant then it neutralizes the oxidation of LDL. Cognitive Health: It helps to increase the stamina and energy and promotes general health and wellness. Anti-aging support: Due to degeneration and advanced age, the aged people have less CoQ10 biosynthesis and body's conversion ability also diminishes in such subjects. A collaborated study carried out on middle aged people demonstrated that subjects who were given this supplement showed marked improvement in their physical and mental activities. Thus ubiquinol by and large promotes life extension and improves the overall mental health by compensating for the age-related conversion disability. Power to other organs: Ubiquinol plays an important role in igniting energy levels within the cells of vital organs like heart, kidneys, liver, and lungs. Thus it naturally helps you to sustain your energy levels. Protects Cells: Ubiquinol protect cells of vital organ like heart from further damage and from constant attack by free radicals. Neuronal Health: Ubiquinol benefits the neurological system and promotes brain health. Studies carried out on patients who had Parkinson's disease have proved that it reduces the functional decline in these patients. Oral Health: Ubiquinol impacts the oral health and significantly enhances the salivary coenzyme Q10 levels. It affects all aspects of mouth, teeth, lips, tongue, and salivary glands. Renal Health: Studies show that Ubiquinol gives significant renal protection to patients who have chronic kidney disease. Your body constantly produces powerful antioxidants daily when you are young. But as you age, your body can not sustain this natural production level forever. Hence ubiquinol supplementation is important to promote overall good health. Ubiquinol can be used as a dietary supplement. Its ready-to-use formula is eight times more effective as it can be readily absorbed by your body. Thus it is an ideal diet supplementation for current CoQ10 users.
At present there are no known side effects of ubiquinol, but if you are on multi-drug therapy or are already taking other supplementations, then please consult your doctor prior taking this diet supplementation Ubiquinol.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2605) Take Control Of your Inflammation With Supplements
Date:
May 27, 2010 12:40 PM
Chronic inflammation is often induced by uncontrolled oxidative stress (free radical damage). It is the principle mechanism by which degenerative disease takes hold. By reducing oxidative stress and changing the balance within the body to favor the production of anti-inflammatory chemical messengers, one can lower their levels of inflammation. This can be achieved through conscious changes to diet and lifestyle, which includes appropriate supplementation. By consuming foods that are rich in omega-3 essential fatty acids, EPA, and DHA, derived from fish oil or flax seeds, one can greatly influence and reduce inflammation. When the body has appropriate balances of omega-3 and omega-6 essential fats, the production of anti-inflammatory prostaglandins is favored and inflammation is kept in check. Increasing the consumption of foods that are rich in omega-3s or supplementing with a high quality fish oil suppresses the formation of harmful prostaglandins and also promotes the synthesis of beneficial prostaglandins. Since the average North American diet contains 10 to 20 times the amount of omega-6 oils that we need, the most sensibly dietary approach is to reduce sources of omega-6 oils and supplement with a high dose of omega-3 oils in order to achieve the optimal 4:1 ratio of omega-6 to omega-3. Supplementing with flaxseed oil is another effective way to optimize your omega-6 to omega-3 ratio. Anti-inflammatory EPA can be manufactured in the body by converting the alpha-linolenic acid that is often found in flaxseed oil. Supplementing with this oil, along with restricting omega-6 fatty acid intake, raises tissue EPA levels to those comparable to fish oil supplementation. It should even be noted that flaxseed oil contains more than twice the omega-3 fats as fish oil. Additionally, alpha-linolenic acid can be found in a variety of other plant source including pumpkin seeds, walnuts, and other nuts. However, flaxseed is by far the richest source of omega-3 oil, carrying 58% by weight. Another nutrient that plays a crucial role in inflammation is gamma tocopherol. This nutrient acts through a mechanism that is unavailable to alpha tocopherol by reacting with RNO radicals to subdue inflammation. Gamma tocopherol also has the ability to reduce inflammation by inhibiting COX-2 , which is an enzyme that has a central role in the inflammatory process as it controls the synthesis of the inflammatory prostaglandin. The consuption of gamma tocopherol has been found to reduce several other inflammatory protagonists at the site of inflammation. Strong evidence has found that this form of vitamin E exhibits potent anti-inflammatory properties that are extremely important for human disease prevention and therapy. Similar to essential fatty acids is resveratrol and green tea polyphenols each of which have the ability to inhibit the activation of NFkB and control a wide variety of inflammatory pathways. Green tea polyphenols are also believed to be neuroprotective, as they invoke a spectrum of cellular mechanisms such as the chelation of metals, scavenging of free radicals, and modulation of mitochondrial function in nerve tissues. Green tea polyphenols are now considered to be therapeutic agents that can alter brain processes and serve as neuroprotective agents in the progression of neurodegenerative disorders like Alzheimer’s and Parkinson’s disease. There are a wide variety of nutrients that are involved in fighting systemic inflammation. These nutrients and nutrient categories include EPA and DHA, linolenic acid, gamma tocopherol, alpha-lipoic acid, vitamin C, flavonoids, procyanidolic oligomers, and the phenolic compounds found in green tea, turmeric, and olive extracts. When changing your diet from saturated fats to unsaturated fats and adds more fruits and vegetables to their diet along with antioxidant vitamin supplements, one can successfully reduce inflammation naturally and live a healthier happier life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2162) Royal Jelly As An Anti-Aging Supplement
Date:
February 27, 2010 11:45 AM
Gelatin is another component of royal jelly and one of the primary precursors of collagen. It is a potent anti-aging compound that helps to keep the youthful, while supporting the organs, glands, and muscular systems. It contains vital fatty acids, sugars, sterols, phosphorus compounds, and acetylcholine. Acetylcholine is essential in order to properly transmit nerve impulses. It is also important for the proper functioning of the endocrine system. An insufficient amount of acetylcholine often leads to a susceptibility to a variety of nerve disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Royal jelly has many properties. Among which include: antibacterial, antiviral, antibiotic, tonic, nutritive, and anti-aging. It is very beneficial to the immune, cardiovascular, endocrine, integumentary, nervous, reproductive, cellular, skeletal, hepatic, and respiratory systems. Although aging is inevitable, the process can be slowed significantly with supplements. Researchers in Argentina have been working to document the ability of royal jelly to both slow down tissue deterioration and even reverse it. For example, the story of Noel Johnson should be noted, as he experienced of rebirth of health at age eighty. In 1964, at age sixty-five he was refused life insurance because of a weak and damaged heart. At this point he was also cautioned to restrict his physical activity in order to prevent death. In 1989, at age ninety, Johnson discussed the book he wrote, The Living Proof… I Have Found the Fountain of Youth, which claims that his use of bee products, along with a solid nutritional program, is responsible for changing his life. Despite the additional exercise and diet changes, Johnson attributes most of his vitality to the bee products he used. He claims that he discovered bee’s gift at age seventy, as the foods restored his manhood, brought him to full vigor and sexual potency, and continue to nourish every cell in his body. Johnson claims to be improving in every way without spending any money on medicine. Royal jelly has been found to help with many conditions. Some of these include menopause, impotence, infertility, chronic fatigue, skin blemishes, wrinkles, immune system problems, viral and bacterial infections, endocrine disorders, hormonal balance, cardiovascular disease, weight control, inflammation, liver ailments, cancer, arthritis, memory, depression, Parkinson’s disease, diabetes, asthma, and mental exhaustion. In order to obtain the best results when using this, or any bee product, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by royal jelly, please feel free to consult a representative from your local health food store with questions. Always buy Name brands like Premier One Royal Jelly to ensure quality and purity of the product you purchase.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2128) Passion Flower Herb
Date:
December 23, 2009 03:36 PM
Passion flower has been found to be extremely soothing on the nervous system. It is used for conditions such as insomnia, hysteria, anxiety, and hyperactivity. Additionally, it is useful for eye conditions such as inflammation, dimness of vision, and eye irritations. Native Americans use this herb as a tonic and poultice for both bruises and injuries. Passion flower was used by the Aztecs as a sedative and for pain. The juice was also used for sore eyes, while the crushed plant tops and leaves were used for treating hemorrhoids and skin eruptions. Passion flower was listed in the National Formulary from 1916 to 1936. This herb was called the nonpoisonous and not dangerous opium of the natural physician by R. Swinburne Clymer, MD. This herb is able to depress the central nervous system, helping with insomnia, anxiety, and nervousness. It may also be useful in lowering high blood pressure. Combinations that contain valerian and passion flower are considered to be very useful as a natural tranquilizer. This herb is also thought to be safe for both children and the elderly. Passion flower contains a variety of complex substances that work on the nervous system and act as a sedative. The components that are responsible for the overall effect are not specifically known. However, maltol, ethyl-maltol, and flavonoids are all thought to contribute. Most research has centered around the sedative action and has found good results. Passion flower extract has also been found to reduce locomotor activity and prolong sleep. Passiflorine is thought to be one of the active ingredients of the plant. It has some similar activity to that of morphine. It contains anti-inflammatory properties that may be helpful in treating those who are suffering from arthritis. An additional benefit of passion flower is its ability to kill a wide variety of organisms. Among these are yeasts, molds, and bacteria. Passion flower works as an antispasmodic on the digestive system smooth muscles and the uterine muscles. This makes it an effective digestive aid for menstrual cramps. This herb contains both calcium and magnesium, which are essential for the nervous system. In short, the passion flower herb is used to provide anodyne, anti-inflammatory, antispasmodic, diaphoretic, nervine, and sedative properties. The primary nutrients found in this herb are calcium and magnesium. Primarily, passion flower is extremely beneficial in dealing with alcoholism, anxiety, spasmodic asthma, high blood pressure, eye infection, eye tension, fevers, headaches, insomnia, menopausal symptoms, nervousness, and neuralgia. Additionally, this herb is very helpful in treating bronchitis, convulsions, depression, diarrhea, dysentery, epilepsy, eyestrain, painful menstruation, muscle spasms, pain, Parkinson’s disease, restlessness, seizures, and poor vision. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by passion flower, please feel free to consult a representative from your local health food store with questions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2120) Pine Bark Extract
Date:
October 07, 2009 11:25 AM
Pine bark extract has become an important herbal remedy due to its antioxidant power. It is responsible for binding with collagen fibers and helping to restore elasticity in the skin. It also protects the body from free-radical damage, which prevents excess and premature wrinkles. Pine tree bark also protects capillaries from free-radical damage that can cause phlebitis, varicose veins, and bruising. Those people who are suffering from skin conditions like psoriasis can also be benefited from pine bark extract. Along with being an antioxidant, pine bark is a natural anti-inflammatory. It helps heal joint pain that is associated with things such as arthritis and sports injuries. This herb helps to control and prevent edema and bursitis. Additionally, pine bark extract may also help in inhibiting cellular mutations like tumors. Reports have found that this herb can help to prevent cellular deterioration in breast tumors and cardiovascular disease. There is also evidence that this herb possesses antiulcer properties that may help prevent the formation of undesirable chemicals in the stomach. Pine bark can also benefit other conditions with its proanthocyanidin therapy. Among these are autoimmune disorders such as lupus, neural problems such as Parkinson’s disease and multiple sclerosis, and vascular problems like heart disease, atherosclerosis, and stokes. Pine bark extract can also treat common complaints such as insomnia, flu, and even the common cold. This herb is very helpful in improving memory, longevity, and the prostate. Additionally, its stimulant properties are responsible for decreasing the production of histamines in allergic reactions like hay fever. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by pine bark extract, please feel free to consult a representative from your local health food store with questions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2099) Mustard Extract
Date:
August 14, 2009 11:49 AM
Mustard is also referred to as mustard greens, Indian mustard, and leaf mustard. This herb is a species of the mustard plant. One of its sub-varieties includes Southern Giant Curled Mustard, which is very similar in appearance to headless cabbage such as Kale. However, it has a distinct horseradish-mustard flavor. It is also known as green mustard cabbage. The leaves, seeds, and stems of the mustard plant are edible. The plant can be found in some forms of African, Indian, Chinese, Japanese, and Soul food cuisine. The leaves are used in African cooking, and the leaves, seeds, and stems are used in Indian cuisine. The plant has a particularly thick stem, it is used to make the Indian pickle and the Chinese pickle. The mustard made from the seeds of this plant is called brown mustard. The leaves are also used in many Indian dishes. This species of mustard plant is more pungent than closely-related greens like kale, cabbage, and collard greens. It is often mixed with these milder greens in a dish of mixed greens, which may even include wild greens like dandelion. Mustard greens are high in both vitamin A and K. Mustard greens are often used in Chinese and Japanese cuisines. Asian mustard greens are typically stir-fried or pickled. The ancient Greeks used mustard for its medicinal value. Additionally, it was used for its flavoring. The Romans also used this herb. They added crushed seeds to wine for a spicy flavor. John Parkinson and Nicholas Culpeper, English herbalists, both recommended mustard for ailments like epileptic seizures and toothaches. The herb was used by Native Americans and early colonists for rheumatism and muscle pain. Mustard is a strong stimulating herb. It is responsible for promoting the appetite and stimulating the gastric mucous membranes to aid in digestion. An infusion of the mustard seed stimulates urine and helps to promote menstruation. Additionally, it is a valuable emetic for narcotic poisoning, as it empties the stomach without depression of the system. Mustard is often used externally as a plaster or poultice for sore, stiff muscles. A plaster of mustard can also be used to treat congestion, warm the skin, and clear the lungs. The seeds of the mustard plant are used to provide alterative, analgesic, blood purifier, caminative, digestive, diuretic, emetic, expectorant, irritant, rubefacient, and stimulant properties. The primary nutrients found in mustard are calcium, cobalt, iodine, iron, manganese, phosphorus, potassium, sulfur, and vitamins A, B1, B2, B12, and C. Primarily, mustard is extremely beneficial in dealing with indigestion, liver disorders, and lung disorders. Additionally, the herb is very helpful in treating appetite loss, arthritis, blood impurities, breath odor, bronchitis, emphysema, sore feet, fevers, gas, hiccups, kidney problems, pleurisy, pneumonia, snakebites, sprains, and sore throat. Before supplementing with this, or any other nutrient, it is important to consult your health care provider. In doing so, you will ensure yourself optimum health benefits. For more information on the many beneficial effects provided by mustard, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2055) skullcap
Date:
August 10, 2009 12:52 PM
The Cherokee tribe used scullcap as an emmenagogue. It was also used historically as an anti-convulsant. An Asian scullcap has been used by Chinese physicians as a tranquilizer, sedative, and to treat convulsion. The herb was used in the eighteenth century as a treatment for rabies by some physicians. Later, it was recommended by eclectic physicians for insomnia, nervousness, malaria, and convulsions. The herb was officially listed in the U.S. Pharmacopoeia from 1863 to 1916. It was also found in the National Formulary from 1916 to 1947. This herb is responsible for treating a variety of conditions. Among these include pain, anxiety, high blood pressure, and epilepsy. scullcap is well known for its ability to calm the nerves and also to help with all nervous system conditions. Additionally, it has been used to treat infertility, fatigue, inflamed tissues, digestion, coughs, and headaches. Some herbalists consider scullcap to be one of the best nervine herbs that is available. It has been used as a nerve tonic. It also can promote a feeling of well-being and promote relaxed sleep. Some people recommend scullcap for problems that are associated with drug and alcohol withdrawal, as it may lessen the severity of the symptoms. Traditional uses of this herb have included infertility, regulation of sexual desire, and as a remedy for cramps and pain. Research one in both Europe and Russia has proven the benefits of scullcap as a tranquilizer as well as a mild sedative. The herb is recommended for use in nervous conditions in order to induce sleep and relaxation. Some evidence has shown that Asian scullcap contains component which inhibit the enzyme sialidase. This enzyme is known to increase in certain disease states like cancer, infections, and inflammations. Another study done in vitro found an antibacterial and antifungal activity in scullcap. Some early evidence has also been found of scullcap’s ability to treat high blood pressure. The herb is used and prescribed widely in Europe. Studies using animals in Japan showed that scullcap has the ability to increase the levels of good cholesterol and prevent serum cholesterol levels from rising. This study was done on rabbits, as they were fed a high-cholesterol diet. These findings suggest that scullcap may also act as a heart disease and stroke preventive. The entire scullcap herb is used to provide alterative, analgesic, antibacterial, antifungal, antispasmodic, febrifuge, nervine, and sedative properties. The primary nutrients found in this herb are calcium, iron, magnesium, potassium, vitamins C and E, and zinc. Primarily, scullcap is extremely beneficial in treating anxiety, high blood pressure, convulsions, epilepsy, infertility, insomnia, nerve problems, and restlessness.
Additionally, this herb is very helpful in dealing with alcoholism, poisonous bites, childhood diseases, chorea, poor circulation, coughing, delirium, drug withdrawal, fevers, hangover, headaches, hydrophobia, hypertension, hypoglycemia, insanity, neuralgia, pain, palsy, Parkinson’s disease, rabies, rheumatism, rickets, spasms, spinal meningitis, thyroid problems, tremors, and urinary problems. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by scullcap, please feel free to consult a representative from your local health food store with questions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2049) Royal Jelly
Date:
June 23, 2009 11:02 AM
Royal jelly is an incredibly rich, creamy, opalescent, white liquid that is synthesized by the worker bees exclusively for the nourishment and cultivation of the queen bee. It is considered the most precious gift of the hive, as it extends the longevity of a bee’s life from six weeks to five years. Royal jelly is incomparable in its ability to enhance both physical and mental performance. Put in a simple manner, royal jelly promotes longevity by helping to maintain health, beauty, and youth. It is extremely potent, highly nutritional, and very natural. Royal jelly is extremely difficult for scientists to completely breakdown its components or synthesize its compounds. No matter how Royal Jelly is studied, certain components of the substance still seem to mystify even the most brilliant scientists. Because of this, duplicating what is thought to be the exact chemistry of royal jelly does not duplicate its effects in the human body. This means that only honeybees can make royal jelly. Royal jelly is rich in proteins and B-complex vitamins, especially pantothenic acid, which is often associated with reversing some of the major effects of aging. Although the chemical makeup of royal jelly may vary slightly according to the location it is found in, the United States Department of Agriculture has analyzed one gram of royal jelly and found in to contain vitamin B1, vitamin B2, vitamin B6, niacin, pantothenic acid, biotin, inositol, folic acid, and vitamin C. Royal jelly also contains vital fatty acids, sugars, sterols, phosphorus compounds, and acetylcholine. Acetylcholine is responsible for the proper transmission of nerve impulses and the proper functioning of the endocrine system. A lack of acetylcholine in the body can make us susceptible to a number of nerve disorders such as Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis. Royal jelly can be purchased in a pure jelly-like material that must be kept frozen or refrigerated. It is also available in capsules, tablets, soft gels, and in honey chewable. Royal jelly is at its ideal best when it is combined with other natural beehive products and complementary botanicals. Because royal jelly spoils very easy, much research has been done on the ability to preserve this key nutrient. One good way to present and preserve royal jelly is within its natural medium of pure honey. By taking freeze-dried varieties of royal jelly, one can also obtain their supplemental dose. A capsulated, freeze-dried variety is an excellent and convenient way to ingest royal jelly. It is necessary to purchase quality bee products in order to obtain the potent and pure varieties of any type of bee food or by-product. It should be noted that a relatively small percentage of the population can experience a laxative effect from royal jelly or bee pollen. Additionally, allergic reactions can happen. However, they are quite rare. Some of these allergies are due to poor quality pollen, as it has been gathered from commercially sprayed flowers or improperly cleaned, dried, or stored. Anyway taking bee products should begin slowly, in small amounts to be sure that an allergic reaction will not occur. Natural bee pollen and royal jelly can be found at VitaNet ®, LLC health food store. Always purchase name brands to ensure that you receive a high quality and pure product.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2023) L-Carnitine
Date:
May 07, 2009 05:45 PM
L-carnitine is amino acid essential for the metabolism of fats into a form of energy necessary for extended aerobic activity. Originally discovered in Russia, and Germany a year later, the structural formulation of carnitine, as it is correctly known, was determined in 1927, although it is physiological and biochemical activity was not understood until the 1960s. The amino acid is biosynthesized in the liver and kidneys from lysine and methionine. The vitamins niacin, B6, C and iron are essential for this reaction to take place. However, the supply of L-carnitine has to be supplemented by the diet, good sources being dairy products, red meat, nuts and seeds, pulses and fruits such as apricots, bananas and avocado. Most of the L-carnitine supply of the body is stored within the muscle tissue. However, it is not unusual for conditions to arise making it difficult for the body to obtain all the carnitine required. L-carnitine enables fatty acids to be transported into the mitochondria, where cell metabolism occurs. The biochemistry is discussed below, although in simple terms the amino acid allows body fats, in the form of triglycerides, to be made more readily available for the generation of energy required for extended exertion. In this way, body fats can be used for energy and the supplies of glycogen stored by the liver can be retained for emergency use. By providing the energy for endurance and stamina in this way, carnitine makes use of an otherwise unavailable energy source, and has the added benefit of reducing body fat stores and reducing strain on the heart. Although there is generally a plentiful supply of L-carnitine available in a healthy diet, supplementation can ensure that a deficiency does not occur. Supplements are available in the form of L-carnitine or its acetylated derivative, acetyl L-carnitine. In order for fatty acids to be used in the production of energy, their long-chain acetyl groups have to get inside the mitochondria where they are oxidized to the acetate to be used for the production of energy via the Citric Acid or Krebs cycle. In order for the biochemistry to take place, fatty acids must be rendered suitable for binding to the carnitine molecule. The chemical grouping with a good affinity for L-carnitine is the acetyl or acetyl group, available in the molecule acetyl coenzyme A (CoA). The free fatty acid, therefore, is attached to coenzyme-A by means of a thioester bond, catalyzed by means of the enzyme fatty acetyl-CoA synthetase. The reaction is then completed by means of in organic pyrophosphatase. In this way, the fatty acid in the form of an acetyL-carnitine derivative can be transported through the mitochondrial wall. This transportation takes place by means of several steps. These are: 1. As explained, the acetyl-CoA is attached to L-carnitine by means of the enzyme carnitine acetyltransferase I. This enzyme is conveniently located on the outer mitochondrial membrane. 2. The enzyme carnitine-acetylcarnitine translocase helps the acetyL-carnitine through the membrane. 3. Another enzyme, carnitine acetyltransferase II, located on the inner mitochondrial membrane, converts the acetyL-carnitine to acetyl-CoA, liberating the carnitine which returns to the muscle mass. L-carnitine is the only known substance that allows fatty acids to cross the mitochondrial membrane, and therefore deficiencies must be avoided. Another way in which carnitine is used in energy production is in the Krebs cycle itself. Part of this cycle involves the conversion of guanine diphosphate to the higher energy form guanine triphosphate. In this way energy can be stored in much the same way as it is in the conversion of ADP to ATP. Succinyl CoA is involved in this conversion, and one of the by-products of it is a corresponding succinate, that is then converted to a fumarate by the action of L-carnitine fumarate. Carnitine, therefore, has two parts to play in the production of long-term energy from the fatty acids contained in body fats. Since the fatty acid triglycerides contained in body fats are a major source of energy in the heart and skeletal muscles, it is easy to understand how L-carnitine is believed to lead to the increased energy levels required for stamina and staying power. A major reason for its effect on longer-term or extended energy requirements is that in enabling stored body fats to be used for immediate and longer-term energy requirements, L-carnitine allows emergency glycogen stores to be retained for use once immediate fatty acid supplies or those of carnitine have been depleted, and so allows the energy supply to be extended even farther. Research has also suggested that the amino acid can possibly be used to treat liver and kidney disease, diabetes and chronic fatigue syndrome. As with many supplements, the question is often asked how does L-carnitine work in practice as opposed to the claims made for it by the supplement providers? Recent research indicates mixed results, but sufficient to justify its use. It is generally accepted that a supplement is necessary when there is a deficiency, but once that deficiency has been corrected further intake is unnecessary. However, it is also believed that during long and extended periods of exercise a carnitine deficiency does occur as L-carnitine is used up, and the supplement is necessary to ensure sufficient energy supply throughout the period of exercise. There has also been a case reported in the Journal of Clinical Neurology (Negoro, Tsuda, Kato & Morimatsu, 1995) where a deficiency, caused by anorexia nervosa damaging the liver to the extent that it was unable to synthesize L-carnitine, was remedied by means of an oral supplement. Studies on endurance athletes have been mixed, ranging from no effect to L-carnitine being found to promote weight loss. Carnitine has no unknown harmful side effects, and has been studied for medical applications other than as an energy supplement. For example it possesses extensive antioxidant properties, and can be used as a supplement against oxidative stress and the prevention of the lipid peroxidation that is a precursor to atherosclerosis. Its use in osteoporosis and reducing bone mass is also being studied. The concentration of L-carnitine diminishes with age, and affects fatty acid metabolism in a number of tissues. Bones are particularly affected since they require continuous reconstruction. Without detailing the biochemistry involved in this, administration of carnitine helps to reduce the speed by which this occurs. Trials are so far been carried out only on animals. In studies on both healthy volunteers and patients with type II diabetes, L-carnitine was found to improve storage of glucose in both groups, although its oxidation increased only in the group with diabetes. Other studies carried out include improving the function of neurotransmitters in the brains of elderly patients and in the treatment of Alzheimer's and Parkinson's disease, and other neurological disorders. In conclusion then, although the jury is out on the use of L-carnitine is an energy-giving or weight-loss supplement, it appears to be effective where the body's stores of carnitine could be depleted such as with long-term exercise, natural deficiencies or deficiencies caused through age. It is also under study in the treatment of various medical conditions. On balance, it would appear that the prospective benefits of L-carnitine render it worthy of use.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2004) L-Methionine
Date:
May 02, 2009 11:41 AM
Methionine is an essential amino acid, meaning that it is not synthesized by the body, and so has to be taken as part of your diet. It also contains sulfur, one of two sulfur-containing amino acids that can form proteins, the other being cysteine. It is a precursor for taurine, which is an aminosulphonic acid, and not strictly an amino acid, which together with cysteine supports the health of your cardiovascular system and helps to eliminate toxins from the body. Maintenance of Cell Membranes It is also an important intermediary in the maintenance of cell membranes. Phospholipids are fat-soluble components of the cell membrane, phosphatidylcholine being a very important example. Also known as lecithin, this substance is derived from choline, itself biosynthesized in a chemical pathway involving S-adenosylmethionine. This substance is made in the body from ATP (adenosine triphosphate) and methionine with the help of the enzyme methionine adensosyltransferase. Known as SAM (or SAM-e), S-adenosylmethionine employs a number of metabolic pathways in its reaction, though generally aminopropylation, transmethylation and transsulfuration. These add aminopropyl, sulfo and methyl groups to a number of substances, the most common being the methylation of proteins, nucleic acids and lipids. Phosphatidylcholine is produced by the enzyme-catalyzed sequential methylation of phosphatidylethanolamine, SAM donating the methyl groups. The maintenance of the integrity of the cellular membrane by phosphatidylcholine is critical to all of the basic processes in human biology, including communication between cells, flow of information and bioenergetics. A by-product of this reaction is homocysteine, formed in the liver from the S-adenosylhomocysteine that SAM is changed to after donating methyl groups. Excess homocysteine in the blood can create the risk of myocardial infarction and cardiovascular disease. SAM is also of use in the treatment of depression and of arthritis. Muscle Development Creatine is a substance well known to athletes as being useful in provide short-term energy for high-intensity training. Although available in the diet, about 50% creatine used by the body is biosynthesized from methionine and two other amino acids, glycine and arginine. It allows a burst of energy lasting about 10 seconds, carried out without the use of glycogen reserves or fatty tissue. Glycine and arginine combine to release ornithine as a by-product, and form guanidino acetate. SAM donates a methyl group to the latter to form creatine, about 95% of which is then stored in the skeletal muscle tissue. The stored creatine phosphate has the effect of allowing the muscle cells to hold more water, which also enables an enhanced level of protein synthesis, and hence an increase in muscle bulk, which also results from the increased blood flow resulting from the short-term high-intensity exercise that creatine allows. Creatine can also increase the levels of MRF4 (myogenic transcription factor), resulting in an increasing in the myonuclei provided by satellite cells to damaged muscle tissue, that not only repair damaged muscle fibers, but also increase their ability to grow. Detoxification of the Liver Substances that help the liver to process fats, or lipids, are known as lipotropic, and the important lipotropics in human biochemistry are imositol, betaine, choline and methionine. They prevent fat from accumulating in the liver, and methionine is also useful in its effect of glutathione. This is a substance that helps the liver to neutralize toxins, such as excessive doses of acetaminophen, and its supplies are regulated by methionine. Methionine and Autism Research into autism is closely studying the Methionine/Glutathione Transsulfuration Pathway. This pathway is a very important biochemical means of detoxification, whereby toxins are methylated and then excreted. This pathway seems to be disrupted in autistic individuals. Not only that, but disruption can lead to oxidative stress which results in many health problems. An example of this is the build-up of the oxidant homocysteine when there is insufficient Vitamin B6 to convert it into cysteine. This has been discussed previously, and is discussed again below. Miscellaneous Benefits Although research is in its infancy, it appears that AIDS sufferers also have decreased levels of methionine in their blood. It is believed that the process of AIDS could be linked to this, particularly the dementia that can occur as a result of the deterioration of the nervous system. It is also hoped that it can help with some symptoms of Parkinson's disease, and pancreatitis. Initial research into this use of methionine has been very promising, as are studies into its use for urinary tract infections. It appears to operate like cranberry in this respect, preventing bacteria from attaching to the cell walls and multiplying in the urinary tract. Methionine is believed to be essential for the formation of collagen, and for healthy pliable skin, hair, nails and other forms of connective tissue. For this reason it is often used as a supplement for the treatment of arthritis, although an excess should be avoided for reasons discussed above. S-Adenosylmethionine generates homocysteine during the biosynthesis of phosphatidylcholine, and this can cause cardiovascular problems. So stick to the recommended doses when you use methionine as a supplement. Used properly, and according to instructions, it offers many health benefits, and can also be used to bulk up your muscle tissue and give increased energy when you need it most. Dietary sources include fish, eggs, lentils, onions, garlic, meat, seeds, spinach and yoghurt. A good supplement would be from 800mg - 1000mg per day, and is best taken along with a B vitamin complex, or at least folic acid and vitamins B6 and B12, in order to prevent the increased generation of homocysteine. Methionine also promotes the excretion of estrogen, so is a possible supplement for women on oral contraceptives that lower the production of this hormone. The elderly might also benefit from a supplement although, if taken for any specific condition, your health professional should be consulted first, as they should be for any supplement. Nevertheless, methionine is a very useful supplement, and can be taken to prevent a large number of conditions. Research is continuing on its effect on AIDS patients, and Parkinson's, and it is hopeful that it will one day be recommended to help people suffering from these conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2002) Alpha Lipoic Acid
Date:
December 11, 2008 11:19 AM
Alpha lipoic acid is the ideal antioxidant for five main reasons. It can scavenge free radicals of all kinds of both fat and water-based cell structures. It rapidly assimilates and absorbs into cells. Alpha lipoic acid boosts the action of other protective compounds. It chelates free meal ions and it also promotes normal cell replication. Alpha lipoic acid (ALA) is both fat and water soluble, which makes it a superior free-radical scavenger because it can protect lipid (fat) and aqueous (water) cell parts from free-radical damage. This ability allows ALA to offer excellent cellular protection because it can easily transport across cell membranes and give oxidant protection outside and inside cell structures. ALA has the ability to freely move throughout all cell parts, scavenging for free radicals in a way that is definitely more effective than other antioxidant compounds. Vitamin C, for example, is a good antioxidant but is strictly water soluble and only affects the interior of cells. On the other hand, vitamin E is only fat soluble, meaning that it affects only the lipid portion of cell structures or the membrane, which leaves other areas unprotected. Cellular glutathione, which is produced in the body and works to neutralize free radicals, is very difficult to artificially boost. Although oral glutathione supplements are available, they have to go through the GI route before they enter the blood stream, leaving little glutathione which actually survives this process. Because of this, cellular levels are not significantly increase by oral supplementation. ALA has been found to help regenerate glutathione by providing extra cellular protection. If the body becomes deficient in ALA, other antioxidant compounds may not work well. ALA plays an important role in boosting the activity of protective compounds such as vitamin E. ALA dramatically extends the life and effectiveness of other vital compounds. ALA has been used for decades to treat diabetic conditions and complications including diabetic neuropathy, with ALA actually having the ability to initiate a reverse in the condition in some cases. Additionally, ALA helps to boost glucose uptake and results in less insulin dependency in some cases. Among its other properties, ALA can protect brain tissue on a cellular level, as well as protect brain cells from certain hazardous chemicals. Research has shown that ALA may even play a role in the treatment of neurological disorders such as Huntington’s disease. As we are all aware, LDL cholesterol has a huge role in the development of cardiovascular disease. LDL cholesterol, which is particularly susceptible to free-radical damage, can be protected by ALA from free radical damage itself. Along with the above properties, ALA has been shown to help in strokes, cancer, cataracts, HIV, liver regeneration, and detoxification. ALA can be purchased in tablet and capsule form and works well when it is orally ingested so that it can be easily assimilated through the walls of the gastrointestinal tract. Taking between 40 to 50 mg of ALA is recommended for best results. The primary applications of alpha lipoic acid are aging, aids, alcoholism, atherosclerosis, bell’s palsy, cataracts, cancer, cirrhosis, diabetes, diabetic neuropathy, multiple sclerosis, liver disease, radiation sickness or exposure, Alzheimer’s disease, senile dementia, stroke, Huntington’s disease, Parkinson’s disease, and heavy-metal poisoning. Have you had your alpha lipoic acid today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1947) Green Tea Extract
Date:
October 23, 2008 01:43 PM
Green tea is a form of tea made from the leaves of the Carmellia Sinensis, a shrub that is native to China and has spread to other areas of Asia including Japan and the Middle East. Drinking it is believed to impart many health benefits, including the prevention of obesity, heart disease and some forms of cancer and it has been used in traditional Chinese medicine for over 400 years. Tea is known to have been consumed in China for around 5,000 years, and used, not only in Chinese medicine, but also in that of Japan, Thailand and India for a number of ailments including regulating blood sugar, treating wounds and digestive problems. The drinking of green tea to benefit the heart and other vital organs is described in the Kissa Yojoki (Book of Tea), written in 1191 by Eisai, a Japanese Zen priest. This two-part book talks about the various medicinal benefits of green tea, such as preventing fatigue, curing beriberi, quenching thirst, clearing the thoughts, maintaining health of the urinary tract and improving digestive problems. It also explains how to grow tea and how to prepare and use the leaves. The methods of treatment of various ailments and medical conditions are described in the second part of the book. The active ingredients in green tea are catechins, polyphenols with strong anti-oxidant properties. Antioxidants are important components of your diet due to their effect on free radicals. These are small molecules, generally oxygenated, such the superoxide cation and hydrogen peroxide that are generated during normal metabolic processes and also ingested in pollutants such as traffic and factory fumes and insecticides. Free radicals are also formed by the effect of the ultra-violet component of sunlight on your skin and other tissues. The effect of free radicals on your body can be devastating, and they not only destroy cell membranes but also oxidize such molecules as the low density lipids (LDL) that carry cholesterol around your bloodstream. This allows the LDLs to be absorbed by the white blood cells and then deposited as fatty plaques in the walls of your arteries. The end result is a thickening and hardening of the arteries that leads to a condition known as atherosclerosis, where the blood supply to the brain and heart muscle is restricted, which can in turn lead to strokes and heart disease. Their effect on your cells is to cause cancer and premature aging, among others, and free radicals are also believed to play a part in conditions such as Alzheimer’s and Parkinson’s disease and also inflammatory diseases such as arthritis and diabetes. They can also cause damage to your DNA. It is essential, therefore, that these free radicals are destroyed as quickly as they are generated, and that is what antioxidants do. You might be more familiar with the antioxidants Vitamins A, C and E, and phytochemicals such as flavonoids and carotenoids, but there are many substances available to you that are even more powerful such as the polyphenols found in green tea. Epigallocatechin gallate (EGCG) is the most powerful of these with antioxidant properties at least twenty five times that of Vitamin E, and 100 times that of Vitamin C. EGCG comprises around 10-50% of the total catechin content of the tea and studies indicate that it likely helps to protect against DNA damage by free radicals, to protect against oxidation of LDL, provide protection against the damage of ultra-violet radiation and to protect you from the free radicals that are generated by smoking tobacco and general airborne pollution. There are suggestions that the bioavailability of EGCG can be increased by consuming black pepper when drinking green tea, possibly due to the presence of piperine in the pepper. The piperine appears to retard the intestinal glucuronidation of EGCG and so allow more of it to be absorbed as opposed to excreted. So if you are using green tea for health reasons, spice up your food with a small amount of black pepper - that's all it needs. You don't have to smother your food in it! It should be stressed that these tests were carried out on animals, although the biochemistry involved is much the same. The oxidation of fat by your metabolism to provide energy is a very important factor in weight control. If the contribution of the fats you ingest to the energy generated by your metabolism is low, then the fats can go on to be deposited in your body. This is not only unsightly, in that it can basically make you look 'fat', but is also dangerous to your health. Fat deposits around your midriff and round the major organs of your body can be extremely damaging and a severe risk to your health. It has been shown by a recent study in the UK (Birmingham University) that those taking green tree extract displayed a 17% increase in fat oxidation over those given a placebo. Not only that, but the ratio of fat oxidation to the overall energy expenditure showed a similar differential between the study and the control group. This provides evidence of green tea extract being able to control your weight by burning fat, and also to improve the tolerance to glucose and sensitivity to insulin of healthy people. Many other health claims have been made for green tea extract, although many of these have little, if any, scientific basis. Among these are the claims that it can treat multiple sclerosis and be used to treat cancer, although claims that it can prevent the destruction of cell membranes due to its oxidative effect are supported by the biochemistry, if not the medical proof. There are cases where theoretical biochemistry can explain many of the applications of ancient remedies without needing modern day studies to support it. Some of the research supporting the green tea theories include: 1. In 2006, a study was announced that had followed over 40,500 Japanese men and women, aged between 40 and 79, that had no history of coronary heart disease, stroke or cancer starting in 1994. It was found that those who drank at least 5 cups of tea per day had a 16% lower risk of dying from any cause and a 26% less risk of dying from cardiovascular disease than those that drank less than one cup of tea each day. Since cardiovascular disease and cancer are the major causes of death world-wide, these are significant results. 2. Again in 2006, it was reported in the American Journal of Clinical Nutrition that studies indicated that a higher consumption of green tea was associated with a reduction in human mental impairment when compared to the average. 3. Yale University School of Medicine reported later that year that, in spite of smoking more than their western counterparts, Asians suffered lower rates of cancer and heart disease, and put that down to them drinking over 4 pints of green tea daily. It was the polyphenol content of green tea and its antioxidant effect that was proposed for this result, known commonly as the 'Asian paradox'. A specific reason given for this was the antioxidant effect preventing the oxidation of LDL cholesterol, and its subsequent deposition in the artery walls. 4. Another component of green tea is the amino acid L-Theanine that promotes relaxation, and it is believed that this could help to fight stress by inhibiting the excitation of cortical neurons.
There is a lot more evidence for the health benefits of green tea, and once again it appears that the ancients have been proved correct. Perhaps we should pay more attention to ancient remedies, although without the proper evidence much of it is ignored - for the time being at least. Green tea, however, has generally been accepted due to the research and studies carried out on ECGC (Epigallocatechin gallate) and in additional to the traditional form, is also available as a dietary supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1923) Green Coffee Bean Extract
Date:
October 22, 2008 04:59 PM
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs. The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition. However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here. The Free Radical Theory of Aging Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them. Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging. Free radicals are generated in the body in four different ways: 1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher. 2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes. 3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting. 4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products. In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body. So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell. Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron. Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals. It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol. The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level. Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging. A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life. There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1922) B Vitamin Complex
Date:
June 23, 2008 03:19 PM
The vitamin B supplement you take is a mixture of nutrients that, although they share the same vitamin letter, are in fact distinctly different chemical entities. The reason that they share the same reference letter of the alphabet is that they are all essential water soluble vitamins (Vitamin C being the only other), they frequently work in synergy with each other and they often come from common sources and have similar properties in the body. They were therefore at one time believed to be just the one chemical entity. They are essential in that they must form part of our diet because our bodies cannot manufacture these substances from others, and although most share common biochemical and health functions, there is no health function that requires all of them, and none of them can be totally replaced by another. The B-Vitamin complex that you take can consist of as many as eight different B vitamins, each of which is essential for a healthy body and at one time it was believed that this mixture was only one single vitamin. That is why they are collectively known as vitamin B and were subsequently allocated numbers: it was only later that the individual components were discovered. These eight are vitamin B-1 (thiamine), vitamin B-2 (riboflavin), vitamin B-3 (niacin), vitamin B-5 (pantothenic acid), vitamin B-6 (pyridoxine), vitamin B-12 (cobalamins), biotin and folic acid (folate). They are found in yeast, liver, tuna, bananas and rice among other sources, and, as with all vitamins, without them life would not be possible. Not all vitamins are found in each of these food sources, and vitamin B-12, for example, is available in nutritional quantities only from animal sources. Knowing what they are is all very well, but what does your body do with the B vitamin supplement that you take? Before considering that, the reason that a regular supply is important is because of their water solubility. This is a useful property for a vitamin to possess, because it means that they can easily be transported by the body fluids to the tissues where they are needed. The downside, however, is that they are consequently also easily flushed from the body, and your body cannot store any of the B vitamins. You therefore must have a regular dietary source that can be augmented through supplementation. This is particularly desirable in alcoholics, those on diets to lose weight and vegans who are advised to take a regular vitamin B-12 supplement. A lack of vitamin B will make you feel tired and lack energy because they play a big part in your body’s metabolism of blood glucose into energy. They also help to maintain a healthy immune system, keep your nervous system in tip-top condition and maintain good healthy skin, hair and muscles. The B complex is also very important in maintaining healthy blood and liver, and each and every component of the mixture has a specific part to play, both on individually and by interaction with others in the B complex. Rather than examining what your body does with the supplement as a whole, let’s have a look at each component, and what your body does with that. Taking them one at a time, thiamine (B1) helps you to burn carbohydrates to generate energy. It is highly water soluble and must be taken daily. In the form of thiamine pyrophosphate it plays a key part in the metabolism of carbohydrates to energy, and also in the metabolism of certain amino acids. If you rely heavily on a high carbohydrate diet, you will need a good regular supplement of thiamine to be able to convert them to energy. Vitamin B2 (riboflavin) also plays a part in fat and carbohydrate metabolism and the formation of adenosine triphosphate (ATP), the molecule of energy. It plays a significant part in the health of your skin and a deficiency is associated with mouth ulcers, cracked lips, flaky skin and bloodshot watery eyes. It also activates vitamin B6 and folic acid, one of the cases where the B vitamins work together synergistically. Vitamin B3, or niacin, is well known to women as a component of some shampoos, and helps to promote health hair. However, this vitamin also takes part in the process of energy creation within your body, and helps to maintain a good muscle tone within the digestive tract. It is also used as a supplement for the treatment of diseases related to high levels of LDL cholesterol and is useful for the treatment of atherosclerosis. Pantothenic acid is also found as a component of shampoos, so no prizes for guessing one of its functions. Vitamin B-5 plays a significant part in the energy-producing Krebs Cycle, or Citric Acid Cycle, that is used by every cell in your body to generate energy just where it is needed. It is also needed to synthesize acetylcholine, a neurotransmitter needed for good brain function and it helps to reduce stress. Pantothenic acid is also closely involved in the production of cholesterol in your liver: cholesterol is not all bad, and is needed by your body to produce some of the steroid hormones and also vitamin D. Amino acids are the small units that are used to biosynthesize proteins and ultimately the genes and DNA that determine who you are. The major factor involved in processing these amino acids is Vitamin B6 (pyridoxine), one of the lesser known of the vitamin B complex. It synthesizes and breaks up different amino acids to produce a variety of other compounds, such as the hormones serotonin, melatonin and dopamine. Deficiencies in these hormones can be very serious, Parkinson’s disease believed to be connected with a dopamine deficiency for example, and other disorders include kidney stones, anemia and many skin complaints. Although deficiency of vitamin B6 is rare, it can occur in alcoholics and those with chronic kidney problems. It is believed that many diets are deficient, however, and a good vitamin B supplement would ensure that this did not occur. Vitamin B-12 is one where deficiency can occur, particularly in alcoholics and vegans. It is available in sufficient quantities only from meat sources, and a supplement is indicated in anyone with a low meat intake in their diet. It is used by your body for the replication of DNA and to allow the normal activity of your body cells. It also helps to control homocysteine levels in conjunction with vitamin B6 and folic acid: homocysteine is a high-risk amino acid associated with atherosclerosis and cardiovascular disease that can lead to Alzheimer’s disease, heart attacks and strokes. The seventh, biotin (sometimes referred to as vitamin B7) also takes part in the metabolism of energy, but deficiencies have not been known, and the final known member of the B vitamin complex is folic acid. This is essential for cell growth and the synthesis of RNA and DNA in the body. RNA (Ribonucleic acid) is responsible for the synthesis of proteins in your body, and the well known Deoxy-ribonucleic acid (DNA) holds the genetic information of your body. Folic acid is therefore essential in the growing fetus, and any other cellular system that rapidly regenerates such as blood cells and the various cells of the immune system. Without folic acid your body would be more susceptible to bacterial and viral attack, and less able to protect you from foreign invaders into your body tissues. Although deficiency is not common, folic acid is present in fresh food only and degrades when stored at room temperature and when cooked. A supplement is therefore advisable during pregnancy to help to prevent neural tube defects. It is evident that the Vitamin B complex plays many parts in the chemistry of your body, and that a supplement can be of benefit in assuring that there are no deficiencies. A good B complex can be found at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1825) DMAE
Date:
June 14, 2008 03:22 PM
DMAE (dimethylaminoethanol) enhances mental function through the improvement of concentration, mental clarity and mental alertness. It is also a mild brain stimulant because it increases and sustains the energy levels in the brain. It also improves the level of restful nighttime sleep because the sleep is deeper and less time is needed to reach a rejuvenated state. DMAE helps to boost mental function through an increase in the levels of acetylcholine and choline. These are the brain’s chemical messengers. Because of DMAE’s ability to stimulate mental cognitive function, it also has been shown to improve learning, increase intelligence and elevate mood. DMAE Benefits: * Accelerates mental processes * Decreases irritability and overactivity * Does not cause drowsiness * Improves concentration * Improves IQ * Increases attention * Relieves mild depression * Aids in long-term treatment of schizophrenia It is believed that DMAE may also increase physical energy. Athletes and other active individuals are using DMAE more and more because of its ability to enhance these brain functions. The connection between the mind and muscles is a means to focus on form and reduce the risk of injury. So, when the mind is enhanced, it communicates better with the muscles to improve and refine function. Due to DMAE’s mild stimulating effect on the brain, athletes report that it is a good alternative for a quick lift instead of coffee. They also believe the stimulating effects last longer than they do with caffeine. DMAE used as a mild stimulant is also safer and healthier than caffeine. How It Works: DMAE, once consumed, is transported to the liver where it is converted into choline through the process of metabolism. A small amount is then converted into acetylcholine, which is a brain transmitter. Through this process, DMAE increases the levels of these brain transmitters (neurotransmitters). This causes a boost in mental cognitive function and memory. Acetylcholine is also responsible for helping to conduct nerve impulses in the brain. Choline is also converted in the brain into phosphatidylcholine. This chemical rebuilds and protects existing cell membranes inside the brain. DMAE has the ability to cross the blood-brain barrier faster than choline. Through this quicker travel, DMAE enhances cell protection and repair and helps our brains function better and create enhanced, positive behavioral changes in most people. Other DMAE Uses: DMAE is being studied for use in aiding a movement disorder in Parkinson’s patients. This disorder, called dyskenesis is caused by L-Dopa, which is administered to treat the effects of the disease. DMAE seems to counteract dyskenesis effectively and safely without interfering with the benefits of the therapy. DMAE is proving to reduce the effects of other disorders that involve involuntary movements. Two of these disorders being treated are blepharospasm (eyelid twitching) and benign essential tremors. Age spot sufferers may find hope for treatment of their condition as well. DMAE has been found to inhibit the formation of pigment caused by aging (lipofuscin) and liver spots (lentigo). It may actually flush lipofuscin from the body, causing the skin spots to disappear over a few month’s time. DMAE is being studied for its possible ability in helping to reduce cognitive impairments related to age. Aside from increased mental cognitive function, research has shown that DMAE may also be useful in treating the following conditions. * Alzheimer’s disease * ADD (attention deficit disorder) * Hyperactivity
The use of DMAE as a regular dietary supplement is increasing steadily. All of its benefits in aiding mental cognitive function and brain stimulation are an attractive quality for everyone. Additional research showing that DMAE is useful in treating debilitating conditions such as Parkinson’s gives us new hope. As research continues and more new uses for DMAE are discovered, its popularity will continue to grow as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1816) Pain Relief
Date:
June 13, 2008 12:18 PM
DL-Phenylalanine has been found to work in conjunction with the body’s natural ability to relieve pain. It helps to lengthen the lifespan of the chemicals in the brain that ease pain. It is especially effective in relieving pain from arthritis and aching muscles. Some chronic pain can be treated with DL-phenylalanine through the stimulation of nerve pathways in the brain that control pain. Enhanced pain relief has been discovered when D-phenylalanine is used in conjunction with prescribed pain killers. This manufactured form of phenylalanine is used to block an enzyme in the nervous system that increases pain signals. The interruption of pain signals allows the healing mechanisms of the body to begin working faster. DL-Phenylalanine is a chemical combination of half L-phenylalanine and half D-phenylalanine. L-Phenylalanine is the natural form of phenylalanine found in proteins all over the body. It is found in foods like beef, poultry, pork, fish, eggs, milk, yogurt, cheese, nuts, seeds and certain soy products. D-Phenylalanine is a synthesized form of the chemical, which means it is produced in a laboratory. Phenylalanine as an Amino Acid: Amino acids perform various major functions in the body. They assist in fulfilling the body’s basic needs from minerals and vitamins. They can act as neurotransmitters, which carry signals to and from the brain. They also aid in other parts of the body for communication between nerve cells. Phenylalanine is one of the essential amino acids found in protein. This means it is required for human health, but cannot be manufactured by the human body. Therefore it has to be supplied through food consumption. It can also be found and taken in the form of powder, capsule, tablet or a topical cream. In the body, phenylalanine is converted into tyrosine, which is another amino acid needed to make protein. It is also needed to make certain brain chemicals and thyroid hormones. Phenylalanine deficiency signs include:
* Confusion Phenylalanine Warnings: A rare disorder called phenylketonuria (PKU) happens in humans who are missing the enzyme required to metabolize phenylalanine. Symptoms of this disorder tend to appear between the ages of 3-6 months. These include:
* Eczema If PKU is not treated within the first three weeks of life, it can cause severe and irreversible mental retardation. Women who are pregnant or nursing should avoid taking phenylalanine as a supplement in any form. DL-Phenylalanine may cause hyperactivity, jitteriness and anxiety in children. Phenylalanine is the major ingredient in the artificial sweetener known as aspartame. Products containing this sweetener are required by law to carry warnings on their labels for phenylketonurics. People who have PKU can be severely injured by ingesting the sweetener. Products containing this artificial sweetener include diet sodas, sugarless gums and some sugar substitutes. Some sugar-free versions of Jello, puddings, ice creams, candies and various other items also contain aspartame. Other Phenylalanine Uses: Some individuals have reported that taking DL-phenylalanine has improved their mood and aided in treating depression. This is the result of a higher rate of production of the brain chemicals dopamine and norepinephrine. These chemicals, when out of balance, cause depression, stress and frustration. Elevation of the levels of these chemicals have an anti-depressant effect in the body. One study suggests that D-phenylalanine has been shown to improve some symptoms associated with Parkinson’s disease. These include: depression, rigidity, walking problems and speech problems. The combination of L-phenylalanine and UVA radiation may be used to treat the symptoms of vitiligo. This condition involves de-pigmentation (white patches) of skin. The use of L-phenylalanine may help to re-pigment these patches, but further study is necessary. DL-Phenylalanine has many uses and benefits if taken correctly. As with any new dietary supplement, consult your physician before beginning a new routine.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1815) Health And Applications Of Coenzyme Q10
Date:
April 17, 2008 02:57 PM
Coenzyme Q10 is a critical cofactor in the biological energy process. It is a powerful antioxidant and plays a vital role in our health and wellness. Coenzyme Q10 is involved in many disease states, consuming adequate coenzyme Q10 can ensure that one maintains good health which can reduce the risk of chronic disease such as the ones listed below: Cardiovascular disease
Neurodegenerative disease
Neuromuscular disease
Many prescription drugs can cause Coenzyme Q10 to deplete especially statin drugs (cholesterol meds). Beta blocking drugs and anti-diabetic drugs can also leach the body of vital Coenzyme Q10 which could lead to the above diseases if left un-checked over time.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1760) Active Coenzyme Q10
Date:
July 07, 2007 01:30 PM
Active CoQ10
The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.
In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. What is ubiquinol? Is it the same or different from CoQ10?
A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.
Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?
A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.
So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.
Q. What are the health benefits of CoQ10 and Ubiquinol?
A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.
In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.
Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?
A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.
Q. How might ubiquinol be important for the heart?
A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.
The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.
Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.
The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.
Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.
Q. What have been the results of research studies with Ubiquinol?
A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.
Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Should I take CoQ10 or ubiquinol? How much should I take?
A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.
Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.
Conclusion
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1583) Papaya- May Be A Fountain of Youth
Date:
May 31, 2007 02:09 PM
Papaya- May Be A Fountain of Youth
Seventy years ago, when the Social Security Administration was developed during the Great Depression, age 62 was recognized as average life expectancy. These days, getting older is a whole different ball game. Not only are people living well into their 80s and 90s, they’re living better, too. People well into retirement are mountain biking, kayaking, jogging and hiking, as well as gardening, golfing and attending concerts – sometimes for their first time. Everybody, it seems, is on the go, from ages of 22 to 92.
Of course, you don’t have to wait until retirement to start planning for a longer more vibrant life. The best way to ensure happier and longer years ahead is to start young.
Nobody wants to spend retirement in the doctor’s waiting room or have their golden years intruded upon with illnesses or infirmities. And, most importantly, we don’t want to feel 80 years old even though our driver’s license says we are.
These desires and demands are not just wishful thinking. Huge advances in the understanding of how men and women age are being made almost daily. These findings are helping to improve our chances of living long, healthy lives. And, some of the most impressive findings have shown that using nutritional supplements can help – in particular, a specially formulated papaya preparation is able to fight two of the primary reasons we get old – oxidative stress and immune system decline.
This issue of Ask the Doctor is going to share the anti-aging secrets hidden in the papaya and how this tropical fruit may hold the key to a long, vibrant life.
Q. Why papaya? What does papaya have that other fruits and vegetables don’t?
A. Not many American moms put a papaya in their kids’ lunch boxes and papaya pie has yet to gain a following. But this tangy tasting fruit is now appearing fairly frequently in the produce departments of most grocery stores and its popularity seems to steadily increase each year.
The papaya’s bright orange flesh is fairly fibrous and very slippery – slicing a peeled papaya is a little like slicing a bar of wet soap. The core is filled with little black seeds that look a lot like caviar. And while eating a papaya will give you a day’s worth of vitamins A and C as well as potassium taking Fermented Papaya Preparation (or FPP) might just give you an additional 30 years of healthy vibrant life.
Q. What exactly is Fermented Papaya Preparation (FPP)?
A. It’s a specialized nutritional supplement. Backed by more than 30 studies to date, FPP has been used in
Q. How was FPP developed?
A. Japanese scientists noticed that individuals with higher amounts of papaya in their diets experienced certain health benefits.
Researchers who study aging decided to look at the papaya’s chemistry to see if it might have properties that could contribute to longevity. Several plant chemicals in the papaya showed promise. And when they combined papaya with specific yeasts and traditional Japanese fermentation techniques, FPP was born. This unique substance was then subjected to scientific studies to see its health impact; they determined that FPP is a superior antioxidant, a powerful immune-booster, and one of
Q. How does FPP help people live longer and healthier?
A. While getting older is an indisputable fact of life, aging, per se, is not. We can’t do much about our annual birthdays and we really shouldn’t even if we could. Every age is a cause for celebration and every life experience, both the difficult and the sublime, should be treasured.
However, we don’t have to accept the consequences of aging that can make a mockery of the “Golden Years” - heart disease, Alzheimer’s disease, Parkinson’s disease, osteoporosis, arthritis, and cancer. Our parents and grandparents and the generations that preceded them might have had little say in how they aged. But we can. We can slow down the harmful effects of aging and FPP can help by reducing oxidative stress and immune system decline.
Additionally, fighting oxidative stress helps people retain their youthful appearance longer. Oxidative damage is the number one factor in facial aging.
Q. What exactly does oxidative stress mean and what does it have to do with aging?
A. One theory of aging is that harmful molecules called free radicals wreak havoc in our cells. Many of our body’s normal metabolic processes produce free radicals. For example, free radicals are a normal by-product in the production of ATP (the energy molecule) from glucose. Certain types of white blood cells destroy invading microbes by the production of free radicals. Free radicals are also formed by the many normal enzymatic actions that take place every minute every day.
However, outside sources can also cause free radical formation, as well. If we are exposed to pollutants in the environment, chemicals, additives and preservatives in the food we eat, or even direct sunlight, excess production of free radicals can occur, causing profound damage. This free radical frenzy is called oxidative stress, and is linked to almost every disease of aging including arthritis, heart disease, cataracts, Alzheimer’s disease, Parkinson’s disease, and cancer. In fact, the reason why these are called diseases of aging is because the longer we are alive, the longer we are subjected to these free radical assaults.
Q. How does FPP affect the decline of our immune systems as we age?
A. Our immune systems consist of specialized tissues, organs, and cells, including several different kinds of white blood cells. Each type of white blood cell works in specific ways to keep us healthy and free of disease. They not only stand guard – on the alert for invaders – they can fight and eradicate microbes, too.
However, as we age, our white blood cells become less efficient in keeping viruses and bacteria from infecting us. They often mistake invaders for good guys, like nutrients. As they age, white blood cells may recognize foreign invaders, but be too tired to fight and let them in. This age-associated immune decline also results in single cancer cells being able to “take hold” and grow into tumors. By the time the white blood cells realize their mistake, the cancer is a widespread disease.
That’s why older members of society have more urinary tract infections, more pneumonia, more cases of bacterial meningitis, tuberculosis, herpes zoster, and much more cancer than younger adults do. Moreover, mortality rates for these diseases are often 2-3 times higher among adults than younger people with the same disease.
FPP steps in and takes charge. One kind of white blood cells, the macrophage “eats” and digests bacteria, viral particles, and free radical fragments. Research has shown that FPP helps macrophages work faster and ingest more disease-causing microbes. Scientists have also discovered that FPP increases the production of a chemical protein called interleukin that’s secreted by macrophages. Interleukin plays an important part in wound healing and keeping minor infections from becoming major infections.
Another important immune system cell is the natural killer (NK) cell, a white blood cell that is continually on the prowl for cancer cells. As the immune system ages, NK cells have trouble “seeing” cancer cells. Researchers have discovered that FPP boosts the activity of NK cells. Increased NK cell activity can result in the increased killing of cancer cells as well as cells infected by viruses.
Q. How does FPP help protect us from free radical damage?
A. FPP contains unique and powerful antioxidants. Antioxidants are molecules that neutralize free radical damage. Antioxidants do this by donating an extra electron to the free radical without becoming frenzied or worked up into a free radical themselves. Although the antioxidant has donated an electron, it has a more stable “personality” and is less reactive. This action stops the domino effect and ongoing free-radical damage.
If you consider your body a temple, think of free radicals as stealing bricks from your temple’s foundation. FPP acts not only as policeman, but as a builder as well. It doesn’t just stop the theft of bricks; it helps create new ones, keeping the foundation strong and young.
FPP does this by affecting super oxide dimutase (SOD) and glutathione peroxidase (GPX), the very genetic pathways that eliminate free radicals from the system. FPP is more than an antioxidant – it doesn’t turn into a pro-oxidant if you happen to take a large dose the way standard antioxidants can. Consider it an “antioxidant plus.”
Since aging is largely determined by how well our bodies can fight oxidative damage, using FPP can slow down the clock as it bolsters natural abilities with its own potent neutralizing activities.
Q. What else does science say about FPP?
A. As the subject of over 30 clinical studies, FPP has been shown to inhibit dangerous hydroxyl free radicals. In addition, it is also being considered for its immuno-protective effects.
Researchers and medical professionals have been studying FPP for years, tracking its effect on the immune system and aging. In fact, no less a personage then Dr. Luc Montagnier, co-discover of HIV 1 & 2 virus, has been conducting research on this natural immune booster.
Dr. Montagnier recommends using FPP as part of a tri-therapy (including antibiotics) that reduces the proliferation of the virus and stimulates the immune system. Since FPP has antioxidant and immuno-stimulative properties, it seems like an obvious choice for a combined approach to combating AIDS. Because of the higher free radical production in stage II of HIV infection, Montagnier believes that reducing this oxidative stress at the earliest stage of HIV infection may be a key factor.
In HIV-infected patients, the glutathione system is depressed even at the early stages. As part of a combination treatment, FPP increased the numbers of CF4 lymphocytes helped with weight gain and increased hemoglobin levels.
One scientific study showed the ability of FPP to inhibit dangerous hydroxyl and hydroxyl-like free radicals, while enhancing the production of protective super oxide. Other research by Dr. Lester Packer, a professor of Molecular Pharmacology and Toxicology at the
And, in one randomized, double blind, placebo-controlled clinical trial, patients with cirrhosis of the liver were given FPP or a placebo. The results showed that 81.2% of the patients survived in the FPP group compared to 38.5% of participants in the placebo group.
These studies and many others like it, show that FPP can neutralize the effects of oxidative stress on disease states as well as slowing the normal aging process.
Q. So if we can prevent oxidative damage to our cells AND prevent decline in our immune systems, how much longer can we expect to live?
A. Most theories of aging and almost all researchers who study aging claim there IS a limit to how long the human body can remain viable. However, the oldest age achieved so far was 128 by a woman named Ma Pampo who lived in the
Right now, Japanese women have the longest life span of any country in the world, with an average life expectancy of 85.93 years. Japanese men live an average 78.87 years.
Q. Is FPP safe?
A. Yes, it is. Many health-conscious people in
Q. What is the recommended dosage level of FPP?
A. Dosages of FPP vary depending on individual needs and usage. For basic anti-aging support, 3 grams per day is fine. For additional support, up to 9 grams per day is recommended. To add a boost to your immune system when you need it, start out with 6-9 grams a day for the first 2-3 days (at the beginning of a cold, for example) and then move back down to 3 grams per day.
For individuals looking for optimum immune support, Dr. Montagnier advises morning and evening doses, preferably on an empty stomach.
Conclusion
As
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1555) The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
Date:
May 18, 2007 01:06 PM
The Awesome Foursome: Coenzyme Q10, L-Carnitine,
D-Ribose, Magnesium
The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.
Coenzyme Q10:
Energy Recycling through the Electron Transport Chain
Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.
Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.
In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.
What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.
Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.
L-Carnitine:
Transporting the Cellular Energy Fuel
Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.
D-Ribose:
Rebuilding the Cellular Energy Pool
As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.
When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.
Ribose is the only compound used by the body to refill this energy pool. Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency. Ribose is made naturally in the cells from glucose. In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis. So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.
Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy. Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days. But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose. Conditions like ischemic heart disease or congestive heart failure fall into this category. In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.
Magnesium:
Switching on the Energy Enzymes
Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism. Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work. Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.
Magnesium deficiency reduces the activity of important enzymes used in energy metabolism. Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function. Small changes in magnesium levels can have a substantial effect on heart and blood vessel function. While magnesium is found in most foods - particularly vegetables - deficiencies are increasing. Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.
Supporting the Links in The Energy Cycle Chain – the Synergy
Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.
The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.
The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.
Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.
These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.
The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.
L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1539) Memory And Focus
Date:
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Like
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Conclusion
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1533) CoQ10 for Heart Health
Date:
March 28, 2007 12:39 PM
CoQ10 for Heart Health
More than 40% of all deaths in the
One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. For what health conditions is CoQ10 used?
A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.
Q. Why is CoQ10 especially important to heart health?
A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.
Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.
Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.
In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.
Q. What studies support this fact?
A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?
A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.
The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.
Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?
A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.
While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?
A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:
1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.
2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.
3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at
4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.
Q. How much CoQ10 should I take?
A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.
CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What are some other heart-friendly supplements?
A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.
Q. What supplements support healthy blood pressure and cholesterol?
A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.
Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.
The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.
Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1501) Neurological Health and CoQ10
Date:
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases. Q. What is CoQ10? A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body. Q. Isn’t CoQ10 a supplement for heart health? A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage. Q. How does CoQ10 affect brain health? A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production. The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced. The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced. Q. What is the blood-brain barrier and why is it important? A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree. Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle. Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier. Q. If CoQ10 is made in the body, why take supplements? A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body. Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10. Q. How does CoQ10 help people with Parkinson’s disease? A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration. A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment. Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months. The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10. The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease. Q. What were the results of clinical research on Huntington’s Disease? A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease. Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness. Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10. Q. What other diseases could benefit from CoQ10 supplementation? A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s. In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health. ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation. Q. Can taking CoQ10 prevent neurodegenerative disease? A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases. Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection. Q. How much CoQ10 should I take? A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day. CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect. Q. What should I look for in a CoQ10 supplement? A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor. Conclusion CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body. All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459) Vitaberry Plus + Super Fruit Antioxidant
Date:
December 07, 2005 05:43 PM
Vitaberry Plus +™ Super Fruit AntioxidantBy Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),- Catalase (neutralizes peroxides), - Functions similar to reduced Glutathione (GSH), - Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent), - Functions similar to Glutathione S-transferase (GST), - Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=992) TMG Fact Sheet
Date:
December 07, 2005 02:13 PM
TMG Fact SheetNeil E. Levin, CCN, DANLA 03/07/05LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups. MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine. TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals. Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot. ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid. TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures. DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably. SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed. COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: General: Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791 Methylation: Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review]. Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30. Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review]. Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31. Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for Parkinsonism. Mol Neurobiol 1994;9:149–61. Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5. Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93. Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review]. Homocysteine: Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8. Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361 Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203 Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266 Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review]. van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83. Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50. Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53. Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499 Liver function: Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German]. Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2. Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5. Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329 Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277 Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6. Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887 Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612 Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61. McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907 Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55. Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439 Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German]. Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644 Autism & Seizures: Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1. Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82. Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6. Immunity: Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6. Safety: Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=988) SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH PYCNOGENOL
Date:
July 13, 2005 12:39 PM
SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH PYCNOGENOL
A REMARKABLE PREDICTION The general consensus among many experts in the health field is that Pycnogenol is destined to become the most vital of all antioxidant compounds. As more scientific evidence presents itself, Pycnogenol may eventually sweep 21st century dietary supplementation.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=611) PYCNOGENOL - ITS REMARKABLE BENEFITS
Date:
July 13, 2005 12:26 PM
PYCNOGENOL - ITS REMARKABLE BENEFITSNew to North America but not to Europe, this natural product is considered safe and effective in the treatment of various diseases and for the maintenance of optimal health. This family of bioflavonoids is non-toxic, water soluble and highly bioavailable. Because proanthocyanidins scavenge free radicals so effectively, they have shown remarkable curative effects. Extensive research demonst rates that proanthocyanidins are such potent antioxidants, they find and neutralize free radicals with great rapidity, allowing cells to regenerate rather than deteriorate. Specific actions associated with Pycnogenol include:
PYCNOGENOL SPECIFICALLY TARGETS: SKIN AND ELASTICITY Testing has suggested that Pycnogenol flavonoids exhibited an anti-enzyme effect which prevented the break down of collagen and elastin, the very compounds which keep skin firm and inhibit the formation of wrinkles.7 TUMOR RELATED DISEASES Unquestionably, studies have shown that Pycnogenol has the ability to inhibit cellular mutations.8 The implications of this finding for anyone suffering from tumor related disease which originates from cellular malfunctions should not be underestimated. CARDIOVASCULAR CONDITIONS The potential of Pycnogenol to pr e vent cellular deterioration or uncontrolled growth is profound to say the least. Several investigations have shown that if it is taken on a daily basis, Pycnogenol benefits people suffering from cardiovascular diseases and breast tumors.9 In addition, double blind placebo controlled studies have indicated that patients suffering from circulatory insufficiencies and diseases of the lymph system showed significant improvement in pain control and vessel elasticity after taking these flavonoids.10 VISION Subsequent experiments concluded that the family of bioflavonoids contained in Pycnogenol is capable of improving night vision and initialing “a rapid and marked improvement of visual performances after glare in comparison with control group.”11 WATER RETENTION AND EDEMA Pycnogenol is particularly valuable for anyone who suffers from water retention and edema. Studies at the Institute of Physiology at the Bulgarian Academy of Sciences confirm that this biofl avonoid compound stabilized capillary walls, which decreased fluid leakage into tissues which causes swelling and pressure.12 WHAT PATHOLOGICAL CONDITIONS RESPOND TO PYCNOGENOL? The bioflavonoids found in Pycnogenol have been clinically indicated in the following pathological conditions:
PYCNOGENOL HAS THERAPEUTIC VALUE FOR THE FOLLOWING CONDITIONS:
PYCNOGENOL CAN CROSS THE BLOOD-BRAIN BARRIER One of the most significant advantages of this flavonoid compound is its ability to cross the blood-brain barrier. Consequently, it acts as an invaluable therapeutic agent in treating depression, chronic fatigue, insomnia or loss of memory. ANTI-ULCER FORMING PROPERTIES Other scientific tests have indicated that proanthocyanidins also posses anti-ulcer properties and may work to prevent the formation of undesirable chemicals in the stomach.13
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=608) Smell Perception, Hearing and Ginkgo
Date:
June 25, 2005 12:00 PM
Smell Perception, Hearing and Ginkgo Over 200,000 visits to the doctor annually are due to lack of smell or the diminished ability to smell properly. In addition, an abnormally heightened sense of smell can also be a problem. Interestingly, these types of smell disorders are commonly seen in people suffering from Alzheimer’s disease or Parkinson’s disease. Both of these disorders are the result of faulty bio-chemical reactions in the brain. Ginkgo is one of the supplements that has been re p o rted to help smell perception. Effective dosages would depend on the degree of severity and the current nutritional status of the person. Ginkgo as a Treatment for Tinnit us When circulation is improved, frequently hearing does as well. Ginkgo helps to oxygenate tissues more effectively which can enhance nutrient transport to the nerves of the inner ear. As a result, conditions such as tinnitus (ringing in the ear) may be alleviated. Tinnitus is a very difficult condition to effectively treat. If the tinnitus is the result of a circulatory deficiency, ginkgo may be effective. The role of ginkgo as a viable therapy for the disord e r remains somewhat controversial. In terms of treating tinnitus with ginkgo, experimentation is the best approach. Tinnitus can be caused by a number of differe n t problems and the search for an effective treatment can only be made by the individual. In addition, treatment must be sustained for a long period of time before any judgement can be drawn. A minimum of two weeks is necessary. For more seve re cases of tinnitus, a longer period of therapy is required. German tests using ginkgo for sudden hearing loss suggested that in cases where hearing is lost for no apparent reason, ginkgo was effective in promoting a remission after one week of treatment. In some cases, hearing was also improved.11 One of the main advantages of using ginkgo over other drugs for hearing loss is that it is considered safe with minimal side effects. Deafness Due to Compromised Blood Flow In some cases of cochlear deafness, ginkgo has proven to be a valuable therapeutic agent. As in the case of tinnitus, treatment should be initiated and sustained.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=458) Green Power
Date:
June 14, 2005 06:11 PM
Green Power by Charles Scott Energy Times, January 4, 2005 If you want to stave off infections, aging-even liver cancer-get your fill of chlorophyll, a vital nutrient in plants. The green in plants possesses unique powers. Green landscapes soothe the soul. A verdant expanse of green vegetation offers comfort, peace and ecological consolation. What makes some plants, including vegetables, green: Chlorophyll, a substance that is also a crucial nutrient for better health. Chlorophyll is a special chemical that consists of molecules which enable plants to collect sunlight. In a complex molecular process, vegetation then uses chlorophyll to harness the power from the sun's rays and build carbohydrates from carbon dioxide and water. Those carbohydrates form the basic nutritional building blocks that we and other animals need to survive and thrive. Besides enabling the creation of carbohydrates, research shows that chlorophyll itself can help lower our risk of diseases like cancer. A recent study in China demonstrates that daily supplements of a chemical derived from chlorophyll can protect DNA, the genetic material in cells. When DNA is damaged and malfunctions, cells may reproduce wildly and become cancerous tumors. The latest experiments, performed by scientists affiliated with the Johns Hopkins Bloomberg School of Public Health and Oregon State University (OSU), show that chlorophyll and its chemical relatives may insulate DNA from unhealthy changes linked to aflatoxin, a fungus that often contaminates corn, peanuts and soybeans. In China, liver cancer associated with aflatoxin is a widespread problem. " In the area of China in which we did our study about one in 10 adults die from liver cancer, and it's the third leading cause of cancer deaths worldwide," says George Bailey, PhD, a professor of environmental and molecular toxicology at OSU. "The findings of this research could be enormously important to many areas of China, Southeast Asia and Africa, where aflatoxin-related liver cancer is a real concern. Many of these deaths might be preventable with supplements that cost pennies a day." This research looked at about 180 people in Qidong, China. When people in the study were given supplements containing chlorophyll derivatives, they had less than half the DNA damage of people who didn't take supplements. According to the scientists, chlorophyll and similar substances may act as interceptor molecules, blocking the absorption of carcinogens. As John Groopman, professor at the Johns Hopkins School of Public Health, observes, the supplements these people took "...can effectively reduce aflatoxin levels, which should reduce the risk of liver cancer." Closer to home, other researchers point out that chlorophyll-rich vegetarian foods may help protect us from carcinogens in the typical American diet. If you've ever enjoyed a hunk of grilled meat, you've consumed substances scientists call heterocyclic amines, which are contained in the charred part of meat cooked on a grill. Studies have shown that these tasty tidbits can increase your risk of breast and other types of cancer. (Your risk from charred meat greatly increases if you are also a smoker.) However, if you eat a food like spirulina, a blue-green algae high in antioxidants that also contains plenty of chlorophyll, its protective substances can bind with these carcinogens within your digestive tract and keep them from being absorbed. Green Keeps You Younger While we always hear that eating more fruits and vegetables enhances our health, new research shows that eating green foods adds extra power to an anti-aging program. Two experiments at the University of South Florida Center for Aging and Brain Repair, published in the Journal of Neurobiology (7/15/02), show that spirulina and other greens can help shield the brain from the antioxidant damage that accumulates as one ages and may help reverse declines in learning and memory. The first study found that a diet rich in spinach helped lab animals stay smart as they grew older. Spinach's benefits, according to the researchers, are due to its rich antioxidant content, which can counteract free radicals (caustic molecules) created in the body during normal metabolism and increased by exposure to environmental pollutants, sunlight and radiation. When free radicals attack, cell walls and other cellular structures are compromised and DNA can malfunction. A lifetime of free-radical damage can slow your thinking and may be one of the causes of Alzheimer's and Parkinson's diseases, says Dr. Paula Bickford, lead author on the project. The second study found that the protective effect of green plants may be linked to their ability to reverse age-related accumulations of potentially harmful inflammatory substances in the brain. In this research, spirulina improved neuron function, lowered inflammation in the brain and reduced levels of chemicals linked to oxidative damage. In fact, spirulina didn't just slow the deterioration of neurotransmitter interactions caused by aging, it actually improved their function. " Not all foods are created equal," says Dr. Bickford. "Cucumbers taste good and have lots of fiber. But unlike spirulina and apples, they are not rich in phytochemicals that have antioxidant or anti-inflammatory effects in the brain." Green Immunity Aside from assisting brain function, spirulina also seems able to help pump up the immune system. Researchers at the University of California at Davis found that adding spirulina to cultured immune system cells significantly increases the production of infection-fighting cells called cytokines. A number of previous laboratory studies have found that spirulina can balance immune response: While easing allergic reactions, this powerful green food also was found to enhance the ability of immune cells called macrophages to both destroy bacteria and eliminate cancerous cells. " We found that nutrient-rich spirulina is a potent inducer of interferon-g (13.6-fold increase) and a moderate stimulator of both interleukin-4 and interleukin-1b (3.3-fold increase)," notes Eric Gershwin, professor at UC Davis. "Together, increases in these cytokines suggest that spirulina is a strong proponent for protecting against intracellular pathogens and parasites, and can potentially increase the expression of agents that stimulate inflammation, which also helps to protect the body against infectious and potentially harmful micro-organisms." What this means for you: Spirulina holds the potential to help the body protect itself against battalions of infectious invaders. " People have used foods like yogurt and spirulina throughout history," says Judy van de Water, PhD, associate professor at UC Davis. "Through research, we are learning exactly how these foods improve immune system function and how they are a beneficial addition to our diet." Throughout the history of life on earth, the healthy development of animal and human life has depended on green plants. Today, as our environment deteriorates and our bodies are under attack from an increasingly polluted world, we need those health-boosting greens more than ever.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=358) Defeat Depression
Date:
June 13, 2005 01:18 PM
Defeat Depression by Cal Orey Energy Times, August 2, 1999 Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery. More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering. Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame. According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life. The good news: Research shows that diet and lifestyle can lower your risk of depression. Birth of the Blues Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes. Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression. The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours. Plan B Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5). Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast. NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions." Moody Spotlight Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression. "SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York. Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e." (Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.) SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant. For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14). 5-HTP: Another popular supplement to boost mood and relieve depression is hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand. "One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts. Herbal Relief St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that hypericum produced fewer side effects than conventional anti-depressants. Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers. "In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner. Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve." Amino Acid Help Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity. For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety. The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine. In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress. Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.) Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins. Depressive Smoking For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally. Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99). "Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers. If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=329) Thanks for the Memory
Date:
June 11, 2005 03:49 PM
Thanks for the Memory by Estelle Sobel , February 6, 2002 Thanks for the Memory By Estelle Sobel "I feel like every day, I lose my memory more and more. It started when I couldn't find my car keys, sometimes I forget directions. My mother has Alzheimer's so I'm concerned," says Jerry Solowitz, a 63 year old man. Ellen Lerner, 37, sometimes worries that she can't keep track of everything in her job as a public relations executive. "I feel like stress can get to me easily, and I worry because I forget simple things like where I put a file." Should these people be concerned? "Yes," says Lynda Toth, Ph.D., co-author with Pavel Yutsis, M.D., of Why Can't I Remember? Reversing Memory Loss (Avery, 1999). Jerry should start a specific program with a health practitioner who specializes in memory loss, due to lots of unsuspected new causes for memory dysfunction. Ellen needs to make lifestyle changes, as stress can definitely lead to memory loss. "Cortisol, which is one of the stress hormones, can be harmful because it keeps calcium in the memory pathway too long and destroys the neurons, which is very damaging to the brain," notes Toth. Why Does Memory Fail? Memory fails for several reasons, says Augustine DiGiovanna, M.D., author of Human Aging: Biological Perspectives, (McGraw-Hill 2000), and Professor of Biology at Salisbury State University in Salisbury, MD. Normal Aging: Much of diminished memory as we age is due to reduced blood flow to the brain from atherosclerosis, which is hardening and narrowing of the arteries. Decreased blood flow causes neurons to shrink and function less effectively. Also, as we age we lose neurons and neuron connections that can lead to memory loss. So the way people think, how much they remember, and the mental activities they do determine how many brain cells survive through the years. Finally, as people live longer, the chance is greater that the body's immune system and other defense mechanisms won't be able to protect against certain diseases that affect the brain and memory (Parkinson's, strokes, Alzheimers, atherosclerosis). A Starving Brain: The brain is not getting fed the nutrients it needs (vitamins, minerals, amino acids, glucose). Without the right "food" the brain's energy levels become lowered and stop powering the memory cells. Then, free radicals can do more dirty work and continue to rust memory cells. Drink And Sink: Alcohol passes through the blood-brain barrier and slows down the processing of information between memory neurons. Memory loss increases over time, as memory tissues shrink. Sad Stories: Depression can imbalance the neurotransmitters and electrical charges of neurons. Tense and Tight: High blood pressure can constrict and narrow blood vessels, limiting blood and oxygen flow to the brain. Memory-Sustaining Supplements One way to boost brain power is to take the right supplements. Ginkgo biloba: The powerful medicinal herb ginkgo biloba increases blood flow and circulation to the head by dilating blood vessels in the brain, allowing more oxygenated blood to get to the neurons. It also protects against free radical damage. Research: Ginkgo biloba extract displayed a significant effect on helping the mental abilities of people 50-59 years old (Phytotherapy Research 13, 1999: 408-415). Pregnenolone: This powerful hormone regulates the balance between excitation and inhibition in the nervous system and helps enhance memory and brain function, possibly by repairing a fatty substance that is part of the myelin sheath that surrounds nerve cells. Research: A St. Louis University School of Medicine study on mice showed that pregnenolone enhanced memory and helped mice to navigate mazes better. Huperzine A: This herbal supplement is derived from club moss found in China; in purified form it inhibits the enzyme that breaks down acetylcholine, a neurotransmitter produced in the brain that you need for memory. Research: Studies conducted by Alan Mazurek, M.D., found that huperzine A in purified form improves memory, enhances focus and concentration and has been used to improve memory loss in Alzheimer's patients (Alt. Ther. in Health Med. 5 [2], March 1999: 97-98). Another study in The Journal of Neuroscience Research showed that huperzine A is a potent inhibitor of cholinesterase, which penetrates the brain and produces a dose-dependent increase of the neurotransmitters acetylcholine, norepinephrine and dopamine in rat cortex (41, 1995: 828-835). Phosphatidylserine (PS): This substance, which occurs naturally in nerve cell membranes, helps keep fatty substances soluble and cell membranes fluid and helps reduce levels of cortisone which are damaging to tissues. Research: Phosphatidylserine encourages a sense of calm by raising the levels of alpha brain waves and increasing the production of acetylcholine (Neuropsychobiology 24, 1990-1991: 42-48). Vitamin E: This potent antioxidant attaches to bad cholesterol and helps prevent free radical damage to cells. Research: Age-related processes like memory function and problem solving can be affected by free radical damage. Several studies show that vitamin E might slow the effects of Parkinson's disease and Alzheimer's disease (JAMA 282, August 18, 1999: 621). Acetyl-l-carnitine: Increases cognitive performance because it rejuvenates cellular membranes of mitochondria, the storehouses of energy contained in every living cell. Alpha-Lipoic Acid: Preserves memory tissue by increasing glutathione levels, which protect fat stores in neurons from being damaged. Nine Ways to Remember Dr. Lynda Toth suggests the following ways to make the most of what you've now got. 1) Power Up Your Smile. Remove dental fillings and replace them with porcelain or ceramic ones. The mercury in metal fillings may be harmful (some believe) and can affect the brain and nervous system, inflaming memory tissue and preventing the entry of nutrients into the cells. 2) Don't Be a Tin Man/Woman Avoid exposure to aluminum. Don't use aluminum pots to cook in. Aluminum accumulates in memory tissue, damaging cells. In fact, autopsies of Alzheimers patients show they have unusually huge amounts of aluminum in the brain. But no one knows where this aluminum comes from. 3) Eat Right. Eat organic and pesticide-free foods. Pesticides get into the cells and can damage DNA. 4) A Matter of Taste. Avoid foods with artificial coloring, monosodium glutamate (MSG, often called "natural flavors" or "natural seasoning"). Also avoid processed foods with taste enhancers called exito toxins such as l-cysteine and aspartic acid. 5) In the Raw. Make sure that your diet consists of enzyme-rich 50% raw foods (fruits and vegetables) to feed the brain. Eat less animal fats. * Drink green juices to support levels of the brain's clean-up enzymes. *Eat lots of fiber, which helps remove toxins from the body. Pick up psyllium fiber. *Limit intake of processed sugar, caffeine and alcohol to lessen the load on the liver and pancreas. 6) Cut Bait. Watch the fish that you eat. Lots of ocean and inland-caught fish are contaminated with mercury. Go for deep, cold water fish such as cod. Avoid shark and swordfish. 7). Oil Up. Supplement your diet with omega-3 fatty acids, such as cod liver oil or flaxseed oil. These fats lubricate memory cells. 8) Work That Body. Stay fit and exercise. Exercise helps oxygenate the body, reduces cholesterol, and builds and energizes new memory cells which reduces wear and tear on the brain function. 9) Do Mind Games. Read, listen to music. Tune into different radio stations than the ones you normally listen to. Do crossword puzzles and a wide selection of word games which can stretch your brain and give it a tough workout. Student of Life You need to keep learning your whole life to keep your brain and memory in tip top shape. The brain is adaptable, and you are always building new neurons, says Dr. Toth, which means that there is no limit to how long it can develop. Anything that stimulates the brain will help it to grow. That's why as you get older it's even more important to take classes, start a new hobby, travel. In fact, the challenge of learning and doing new things (without stopping in a fit of frustration) causes your brain to grow, says Dr. Mazurek. The Good News As people get older, their brains may actually improve and repair themselves through a complicated process that is designed to eliminate faulty neurons that are prone to making mistakes. At the same time, brain activity goes on that results in the development of new and improved connections with neighboring neurons. Research also shows that memory improves if you train people to have faith in themselves. (The brain helps those who help themselves.) Apparently, a confident perspective can encourage the brain to actually improve to the point where its new-found abilities may increase to the point where it fulfills expectations. So keep your chin up and stay away from the artery-clogging saturated fat that can cut off the brain's blood supply. It's all in the attitude, says Dr. DiGiovanna. And, of course, the key to a long and happy life with your brain is also on the end of your fork and in that bottle of supplements. Estelle Sobel, is the co-author of Beautiful Skin: Every Woman's Guide to Looking Her Best at Any Age (Adams Media, May 2000).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=289) Mucuna Pruriens (DopaBean)
Date:
May 30, 2005 11:26 AM
Mucuna and Medicine Mucuna pruriens, commonly known as velvet bean or cowitch, is a plant indigenous to India A clinical study confirmed the efficacy of the seeds in the management of Parkinson’s disease by virtue of their L-Dopa content1,5. Mucuna pruriens, recognized as an aphrodisiac in Ayurveda, has been shown to increase testosterone levels2, leading to deposition of protein in the muscles and increased muscle mass and strength3. The extract is also known to enhance mental alertness and improve coordination4.
1. Manyam, B.V., et. al. (1995) J. of Alternative and Comp. Med., 1 (3) 249-255.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=114) 
Date:
May 09, 2005 10:08 AM
Calm Child™
Calm Child is a clinically derived herbal formula, specifically designed to support many body systems that are critical to the health and well-being of children. It is truly a multi-purpose herbal treasure, useful for supporting the health of the immune system in winter, enhancing digestive processes, and promoting restful sleep issues commonly experienced by most children. It also helps defend the system against the negative effects of stress, eases occasional restlessness, and promotes calm focused attention. The Challenged Child Difficulty in focusing and concentrating is one of the fastest growing problems for children today. This is a "new" problem, recognized as such over the last thirty years of the twentieth century. In the nineties, up to 5 percent or more of all school-age children were identified as having issues with focus (greater than 5 million children in 1995, over 25% higher than in 1985!). Since then, this number has continued to grow. Signs of the problem include the following and must be present for at least six months in more than one setting (home, school, etc.) especially before the age of seven: distractibility (inattention); inability to concentrate or focus; impulsivity (poor self-control); and excessive activity. Of course, measures of all of these are very subjective and are a part of the development of almost every child. Additionally, situations such as premature separation from parents, or unresolved emotional issues, or a family crisis, can cause children to withdraw or, conversely, act out due to an inability to appropriately express their feelings. Further, excessive and violent TV and computer games, lack of physical exercise, and poor diets can cause over-stimulation, internally and externally. Determining when such behavior is a problem is subject to interpretation. Too often, children are provided with a diagnosis before they are out of pre-school and are far too often prescribed pharmacological interventions such as amphetamines (Ritalin). The Birth of Calm Child My husband, Michael Tierra, originally formulated Calm Child for our own child, Chetan, then one year old, to address a wide array of potential childhood issues. His underlying intention was to use Calm Child for all children, based on his belief that most childhood emotional complaints are due to the unconscious pain of separation from the security and comfort of the womb. It was also based on the fact that historically, botanicals have been widely used to support the development of healthy children. Chamomile and lemon balm are perfectly suited for this purpose. Both are incredibly gentle-acting and deliciously fragrant botanicals that promote relaxation and calmness. Both also address underlying digestive imbalances that can give rise to occasional irritability and restlessness. The Calm Child Formula The herbs in Calm Child have a long history of use for calm focused attention in children: Lemon Balm: In his herbal of 1640, the renowned English medical botanist John Parkinson quoted Serapion the Younger (802-849) who said lemon balm is used "to cause the mind and heart to become merry...to strengthen the weakness of the spirits and heart, and to comfort them..." This belief in the comforting effects of lemon balm persisted and was repeated by Avicenna, who stated "it makes the heart merry and strengthens the vital spirit." In the 16th century, the renowned herbalist Nicholas Culpeper reported on the use of lemon balm for melancholy and sadness. Herbalists and midwives today continue to use lemon balm for the same purposes. Chamomile: Well-known in the nineteenth century, chamomile was used for crying, weepy children and to support calm digestion. Herbalists have long recognized a relationship between upset stomachs and restless children. Today, it is still widely used in homeopathy for babies' teething and children's clinginess. Other complementary ingredients in Calm Child include: jujube seeds (zizyphus), one of the most nourishing and relaxing nerve tonics used in Chinese herbalism; the incredibly nourishing berries of hawthorn and amla; the calming, aromatic, and digestive promoting effects of catnip, anise, clove, and long pepper; the legendary gotu kola for promoting mental well-being and attention; and the minerals magnesium (taurinate) and calcium (citrate), both necessary for normal nerve and muscular function. Works in Three Important Ways Together these botanicals work in three important ways to promote calm focused attention in children. They: 1) promote a calm relaxed nervous system; 2) provide added nourishment which is essential for normal brain function; and 3) support a calm and healthy digestive system which is often an underlying cause of childhood restlessness. Clinical Experience Calm Child was developed more than 20 years ago and has been used by literally tens of thousands of children worldwide. In my own clinical practice, I have found Calm Child to have a wide range of uses. It is great as a wintertime supplement, to support normal digestion, promote relaxation and sleep, and perhaps most important, to cultivate a strong, centered, focused sense of mental and emotional well-being, specifically in children though many parents of active children have benefited from it as well. When it is given in conjunction with a diet that is low in refined sugars and food colorings and additives, parents report tremendous success in dealing with teething, occasional headaches and digestive imbalances, increasing attention in school, or helping their children cope with the stresses of day care. Dietary Considerations For best results, herbs are always given in conjunction with diet and lifestyle recommendations. When using Calm Child, make sure the child is eating sufficient protein for his/her needs along with lots of cooked vegetables and some whole grains. Include some fruit, but keep fruit juices to a minimum as they contain too much simple sugar for children. Eliminate sugar, white flour products, foods with colors and preservatives, and caffeinated products as much as possible. Be sure to give plenty of water (many children never drink water but depend on juices or sodas instead!). Also, children inherently have much more energy than their parent and teacher handlers who try to make them sit still and focus on something that has little meaning to them. Make sure they get plenty of physical exercise to burn off some of the energy that teachers and parents have difficulty harnessing.
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Jiaogulan is also known as Gynostemma pentaphyllum is an adaptogenic herb and the vine from the Cucurbitacea family of plants that grows naturally in Asia, and most specifically in China, Japan as well as in Korea. This plant is related to plants such as the watermelon, pumpkin, cucumber as well as to the gourds. Praised in China as xiancao, the Jiaogulan herb is an incredibly useful life giving plant, the herb of immortality with a powerful adaptogenic capabilities and antioxidant properties. Its adaptogenic capability is derived from its components and substances that aids in revitalization thus bringing the whole body back into balance.
Nicotinamide Adenine Dinucleotide (NADH) is an activated form of B vitamin niacinin, which is available naturally in the body, from poultry, meat, fish and in minimal quantities from vegetables and fruits. This substance is also commonly referred to as the most important coenzyme mainly because of the import role of transforming food-based energy into energy, which can be utilized by the body cells. Due to the roles played by NADH, it has been developed into supplements, which have various benefits. NADH role in the body is important since the body cannot utilize the energy inform of whole proteins, carbohydrates and fats which are the main sources of energy. 
Gluten intolerance arises when your body cannot digest gluten, which is a protein found in rye, barley and wheat. It makes the immune system to attack small intestines lining’s which causes diarrhea, abdominal pain and nausea. It’s commonly called celiac disease. Apart from celiac or gluten intolerance other health issues caused by gluten have come up. 
NADH is a chemical that is naturally created in the body and plays the role of generating energy, NADH stands for Nicotinamide Adenine Dinucleotide with hydrogen.
All that you may need to know about antioxidants 
First of all what is Creatine? Creatine is a protein that is produced by the human body and converted to creatine phosphate and stored in muscles. The stored form can then be utilized for energy by the muscles. It is also found in meat and protein rich food products such as fish. Some clinical studies have surmised that creatine as an oral supplement enhance muscle strength and increase lean muscle bulk. 
Royal jelly is considered to be the treasure of the beehive. It has the ability to promote longevity by helping to maintain healthy, beauty, and youth. This natural food is extremely potent and highly nutritional. Royal jelly is an incredibly rich, creamy, opalescent white liquid. It is produced by the worker bees specifically for the nourishment and cultivation of the queen bee. This fantastic material converts a common honeybee into a queen bee, extending the bee’s lifetime from six weeks to five years. This substance is full of natural hormones and B-vitamins. Additionally, it contains a variety of seventeen amino acids. Eight of these amino acids are essential. Royal jelly is particularly rich in cystine, lysine, and arginine and is also composed of 16.1 percent aspartic acid, which is crucial for proper tissue growth and regeneration. 
The passion flower comes from a genus of about five hundred species of flowering plants. These herbs are mostly vines, although some are shrubs. A few of these plants are herbaceous. 
Many Native American tribes relied on the bark of pine trees for its ability to treat a number of disorders. The Annedda pine was called the “tree of life” due to its marvelous healing benefits. Jacques Cartier, a noted explorer in 1535, wrote in his diaries about the early medicinal uses for 
Pine bark extract also helps with eyesight. It is responsible for reducing the risk of and treating diabetic retinopathy. Multiple studies have concluded that it is beneficial in improving night vision. One study even found marked improvement in visual performance in the proanthocyanidin group over a placebo group. 
