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  Messages 1-48 from 48 matching the search criteria.
Vitamin D deficiency directly linked to your risk for cancer Darrell Miller 1/5/19
relationship-between-diabetes-and-thin-people Darrell Miller 8/26/17
30 surprising food swaps that will immediately improve the health of every organ in your body Darrell Miller 7/27/17
10 cannabis guidelines released in American Journal of Public Health Darrell Miller 6/24/17
10 Ways To Use Diatomaceous Earth (And The Benefits) Darrell Miller 6/7/17
Jarrow challenges FDA on probiotics Darrell Miller 6/5/17
Bioperine: Powerful Synergistic Compound Darrell Miller 5/29/17
Pros and Cons to Know About the Atkins Diet Darrell Miller 5/10/17
16 Best Oils To Diffuse And How To Do It Right Darrell Miller 4/19/17
You Really Need to Join a Gym Darrell Miller 3/16/17
Skipping breakfast may be bad for your heart, doctors say Darrell Miller 2/8/17
Skipping Breakfast Could Increase Your Risk Of Heart Disease Darrell Miller 2/6/17
These Are the Drugs That Cause the Most Overdose Deaths Darrell Miller 1/2/17
Replacing carbs with protein? Don't overdo it Darrell Miller 12/17/16
Magnesium Does a Heart Good; Long Live Optimism; Post-Stroke Epilepsy Darrell Miller 12/15/16
World's oldest living person has eaten 3 eggs a day for over 90 years Darrell Miller 11/11/16
Curcumin Helps Alleviate Depression Darrell Miller 10/26/16
Is Cocoa Butter Good For The Skin? Why? Darrell Miller 3/6/14
Melatonin CAn Help You Sleep Better in a natural way Darrell Miller 12/22/13
Benefits of magnesium chelate Darrell Miller 6/23/12
How Do I Use Phytoestrogen And Progesterone Creams For PMS? Darrell Miller 9/22/11
Best Probiotic Supplements For A Healthy Intestinal Tract Darrell Miller 12/9/10
Colostrum Darrell Miller 6/18/09
Multiple Vitamins Darrell Miller 2/4/09
Flaxseed Oil Darrell Miller 12/23/08
Red Yeast Rice Darrell Miller 8/4/08
Regulating Blood Pressure Naturally Darrell Miller 3/28/07
Lower Cholesterol Naturally! Darrell Miller 10/6/06
Remifemin symptomatic relief, scientifically supported* Darrell Miller 8/26/06
What are you really Getting? Darrell Miller 8/21/06
Ergopharm Dietary Supplements Darrell Miller 7/29/06
Lutein to fight age-related macular degeneration! Darrell Miller 2/27/06
Devine Skin - New to VitaNet to help all your Hair and Skin needs. Darrell Miller 2/25/06
Now Foods -QUALITY- High Standards and Attention to Detail Darrell Miller 12/27/05
Vitaberry Plus + Super Fruit Antioxidant Darrell Miller 12/7/05
Source Naturals - Continuous Quality Assurance Darrell Miller 8/20/05
Common Sense Guidelines for Avoiding the Flu and Colds Darrell Miller 7/28/05
In men under 65, prostate surgery can save lives. Darrell Miller 7/27/05
The Role of Naturally Occurring Progesterone in the Body Darrell Miller 7/25/05
Pain - Post Op and Relaxation Darrell Miller 7/13/05
REFERENCES Darrell Miller 6/25/05
Toxicity and Safety Darrell Miller 6/25/05
PADMA BASIC: A Tibetan Herbal Formula Darrell Miller 6/21/05
Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement Darrell Miller 6/21/05
Fats: The Good, the Bad, the Ugly Darrell Miller 6/14/05
Nutritional Scorecard Darrell Miller 6/14/05
Cancer at the Millenium - the war on cancer entering its third decade... Darrell Miller 6/13/05
Re: Its in the Blood Darrell Miller 5/9/05




Vitamin D deficiency directly linked to your risk for cancer
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Date: January 05, 2019 10:12 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin D deficiency directly linked to your risk for cancer





The Institute of Medicine has historically recommended the average individual taking in 20 ng/mL of vitamin D each day, but now studies are showing that this may be much lower than what our daily intake should consist of. Researchers at UC San Diego recently preformed a case study that showed patients who took in 48 ng/mL of vitamin D each day were shown to reduce their cancer risk by up to 67%. These staggering results show that the Institute of Medicine may have to redetermine their daily guidelines.

Key Takeaways:

  • Researchers have published the results of some studies that shows that optimal levels of Vitamin D, like 48 ng/mL, can lower one’s risk of having cancer.
  • The institute of medicine has been recommending a level of 20 ng/mL for years but this study found that it was not close to the optimal.
  • In fact, higher levels of sun exposure in one’s lifetime, as seen in southern latitudes, reduce one’s risk of having breast cancer.

"You might be making a conscious effort to consume more superfoods and get more exercise, but are you keeping tabs on your vitamin D levels?"

Read more: https://www.naturalnews.com/2018-12-26-vitamin-d-deficiency-directly-linked-risk-for-cancer.html

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relationship-between-diabetes-and-thin-people
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Date: August 26, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: relationship-between-diabetes-and-thin-people





Diabetes is often associated with overweight people who develop it after poor eating and lifestyle habits. But there is also a non-obese driven diabetes sometimes referred to as Thin Diabetes. Stomach fat can be a factor but even those with what appears to be little stomach fat can develop diabetes. Overall body weight can be deceptive too since a person's weight might fall within Guidelines but their pancreas is not providing enough insulin which helps sugar get into cells for energy. This type is known as Type 1 Diabetes.

https://www.youtube.com/watch?v=xvV1C3j8eyU&rel=0

Key Takeaways:

  • You can be thin and still be at risk for diabetes. It's a misconception that obese people are only at risk
  • Diabetes is becoming an epidemic. You are starting to see children with diabetes more now than ever.
  • Many people are diabetic and do not know it because they have no symptoms.

"Diabetes Type 2 is the most widely recognized type of Diabetes, which makes up around 90% of Diabetes cases globally."

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5181)


30 surprising food swaps that will immediately improve the health of every organ in your body
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Date: July 27, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 30 surprising food swaps that will immediately improve the health of every organ in your body





All of us have favorite foods, dishes, go-to condiments, that appear invariably on our plate. Whether it’s the easy-to-make no-fuss nature of the choice, the it’s ‘what my store carries appeal,’ or it just boils down to how our taste buds feel about it, we can get in nutrition rut.

Fortunately, it’s not that hard to start swapping items we use daily for other easy-to-use items that taste good, even often having a similar taste and texture to those items we already use. The plus is that the swapped in items are better for us. Better, because they’re higher, in things that matter, like protein, amino acids, fiber, vitamins and minerals, besides being lower in things we should want to avoid, like empty calories, trans fat, excess carbs, and more.

By swapping some things daily, such as trying cinnamon, or organic honey, over sugar, substituting plain, organic coffee for that latte, a veggie wrap, for that bread and meat sandwich, could have big overall benefits in reduced pounds, renewed energy and a better overall nutritional profile, making for a healthier you.

Key Takeaways:

  • Swapping out healthier ingredients in your recipes can improve your overall health
  • Sugary and starchy foods can be replaced by natural and healthy alternative
  • Guidelines,swaps and healthy recipes can be found in the provided article.

"Coffee often gets a bad rap when in fact, quality coffee consumed in moderation can have some great benefits."

Read more: https://www.healthnutnews.com/30-surprising-food-swaps-that-will-immediately-improve-the-health-of-every-organ-in-your-body/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5043)


10 cannabis guidelines released in American Journal of Public Health
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Date: June 24, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 10 cannabis Guidelines released in American Journal of Public Health





There are 10 cannabis guidelines that were released in the American Journal of Public Health. Public health and medical experts are supporting ten brand new recommendations that will help to reduce the health risks of using cannabis. Cannabis use has health risks that are best avoided by abstaining. Another recommendation is to delay taking cannabis until much later in life. You should also avoid smoking cannabis. You can choose safer ways to use it. Avoid harmful smoking practices as well.

Read more: 10 cannabis guidelines released in American Journal of Public Health

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10 Ways To Use Diatomaceous Earth (And The Benefits)
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Date: June 07, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 10 Ways To Use Diatomaceous Earth (And The Benefits)





Diatomaceous earth 9or DE)is a type of soil that can be beneficial to your health, it can even be eaten for it's health benefits. DE is an environmentally safe insect repellant. For your personal health it can detox your body, lower blood pressure and reduce chronic inflammation. It's also beneficial for your skin and hair. Other benefits and uses are explained in this article. It's important that you follow the guidelines in this article to use DE safely and effectively.

Key Takeaways:

  • Diatomaceous Earth can be used as a safer means of pest control: both to rid the home of pests as well as keep pests out of the garden.
  • Diatomaceous Earth has great health benefits for skin, hair, detoxification, blood pressure and digestion.
  • Diatomaceous Earth is so safe that one can add it to water for drinking, although one should consult a health professional first.

"When we take responsibly from the earth’s bounty, we can find everything we need for sustenance."

Read more: http://www.thealternativedaily.com/ways-to-use-diatomaceous-earth/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4787)


Jarrow challenges FDA on probiotics
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Date: June 05, 2017 11:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Jarrow challenges FDA on probiotics





Jarrow Formulas Inc. has released a 32 page comment challenging the FDA on it's stance on probiotics. It notes how the FDA won't approve the term probiotics in several cases, instead using the phrase active cultures and just how the FDA labels probiotics in general. The company also takes issue with the fact that fermentation is considered chemical alteration under the current guidelines. The draft was vetted by the supplement company's lawyers and could dramatically change dietary guidelines if accepted.

Read more: Jarrow challenges FDA on probiotics

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Bioperine: Powerful Synergistic Compound
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Date: May 29, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Bioperine: Powerful Synergistic Compound





Bioperine is an extract found in many pepper plants. It is related to the turmeric family. It has been tested in animals to possibly lower cancer rates in humans. It can also possibly boost your metabolism and encourage weight loss. It is easier to introduce in the market as a food rather than a pharmaceutical supplement. The product can also warm internal body levels and improve digestion which helps your body absorb more nutrients. Bioperine is a relatively safe product.

Key Takeaways:

  • standardized ingredients are important for supplements so that you receive the same results with each use.
  • Piperine has been shown to reduce weight by 20% and have strong anti-cancer actions in animal studies.
  • Adherence to quality is the most important quality to look for in a supplement because under the FDA's guidelines, one could simply use table pepper and sell it as piperine extract.

"This novel compound is one of several bio-active alkaloids found in these plants, and offers a slew of remarkable health benefits"

Read more: https://www.organicnewsroom.com/bioperine/

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Pros and Cons to Know About the Atkins Diet
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Date: May 10, 2017 10:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Pros and Cons to Know About the Atkins Diet





The Atkins diet has been around for a number of years. Many people love it because it helps you lose weight quickly and it helps prevent many crippling diseases. It also can be quite easy to follow since it doesn't require calorie counting or measuring. You simply need to follow some guidelines as to what you can eat and then the weight comes off. It also has several things going against it. It can cause discomfort because it can make you very tired, making it harder to exercise. It can also cause some stomach issues. Bad breath can also be a side effect. It doesn't allow for a wide variety of foods. Therefore, you have to weigh the pros and the cons before attempting this diet.

Read more: Pros and Cons to Know About the Atkins Diet

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16 Best Oils To Diffuse And How To Do It Right
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Date: April 19, 2017 05:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 16 Best Oils To Diffuse And How To Do It Right





With aromatherapy becoming increasingly popular, it is easy to become confused on what to use, and when to use it. Knowing and understanding the various oil options is essential to maximizing their full potential for use. Research shows that oils can have a positive impact on stress reduction and overall health. Once you learn about the benefits of each, you can then begin experimenting with mixing the oils. Be sure to pick up a diffuser and follow the Guidelines to achieve optimal benefit.

16 Best Oils To Diffuse And How To Do It Right

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You Really Need to Join a Gym
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Date: March 16, 2017 11:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: You Really Need to Join a Gym





There are those people that love the gym…I bet you’ve even got a picture of them in your minds eye right now. And then, there are those of us who cannot stand it. So much grunting and weight dropping. No thanks. However, according to a new study, published in the journal PLOS ONE, club members have a benefit over the rest of us when it comes to getting regular exercise. (Maybe this article will even convince you to join that gym you’ve been driving by every day since January 1st!)

Key Takeaways:

  • Iowa State University scientists recruited 405 relatively healthy adults; half had already belonged to a gym for at least 30 days and half hadn’t been members for at least three months.
  • The team analyzed all the participants responses to figure out which of them met the national recommended Guidelines for physical activity.
  • The current recommendation is 150 minutes of moderate or 75 minutes of vigorous aerobic activity each week and at least two days of weight lifting

"However, according to a new study, published in the journal PLOS ONE, club members have a benefit over the rest of us when it comes to getting regular exercise."



Reference:

//www.healthnutnews.com/really-need-join-gym/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4176)


Skipping breakfast may be bad for your heart, doctors say
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Date: February 08, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Skipping breakfast may be bad for your heart, doctors say





Are you eating your breakfast? It has long been reported that breakfast is the best meal of the day, and new research suggests that going without it may do even more damage, particularly to your heart. What should you know about breakfast and the risks of not enjoying this meal as you should?

Key Takeaways:

  • Planning meals and snacks in advance and eating breakfast every day may help lower the risk of cardiovascular disease, new Guidelines from U.S. doctors say.
  • Eating more calories earlier in the day and consuming less food at night may also reduce the odds of a heart attack, stroke or other cardiac or blood vessel diseases, according to the scientific statement from the American Heart Association.
  • adults may routinely skip breakfast, a habit that has become more common in recent years as more people snack throughout the day instead of sitting down for three traditional meals.

"Eating more calories earlier in the day and consuming less food at night may also reduce the odds of a heart attack, stroke or other cardiac or blood vessel diseases, according to the scientific statement from the American Heart Association."



Reference:

https://www.yahoo.com/news/skipping-breakfast-may-bad-heart-doctors-194756265.html?ref=gs

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Skipping Breakfast Could Increase Your Risk Of Heart Disease
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Date: February 06, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Skipping Breakfast Could Increase Your Risk Of Heart Disease





It turns out that you actually need breakfast because not having it could enhance your risk of having heart disease. Planning your meals and snacks and eating a healthy breakfast everyday will help to lower the risk of you getting heart disease. It's also important to eat less during the night time and eating more calories during the day.

Key Takeaways:

  • Eating more calories earlier in the day and consuming less food at night may also reduce the odds of a heart attack, stroke or other cardiac or blood vessel diseases, according to the scientific statement from the American Heart Association.
  • “When we eat may be important to consider, in addition to what we eat,” said Marie-Pierre St-Onge, chair of the group that wrote the Guidelines and a nutrition researcher at Columbia University Medical Center in New York.
  • As many as 30 percent of U.S. adults may routinely skip breakfast, a habit that has become more common in recent years as more people snack throughout the day instead of sitting down for three traditional meals, St-Onge and colleagues note in the journal Circulation.

"Eating more calories earlier in the day and consuming less food at night may also reduce the odds of a heart attack, stroke or other cardiac or blood vessel diseases, according to the scientific statement from the American Heart Association. “When we eat may be important to consider, in addition to what we eat,” said Marie-Pierre St-Onge, chair of the group that wrote the Guidelines and a nutrition researcher at Columbia University Medical Center in New York."



Reference:

//www.huffingtonpost.com/entry/skipping-breakfast-could-increase-your-risk-of-heart-disease_us_589214a7e4b02772c4ea957a

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3895)


These Are the Drugs That Cause the Most Overdose Deaths
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Date: January 02, 2017 08:19 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: These Are the Drugs That Cause the Most Overdose Deaths





A new report has shown that the number of deaths caused by an overdose of Fentanyl has doubled in a single year. The Food and Drug Administration has issued warnings and Guidelines to combat the rising epidemic that has effected more than 1.9 million people since 2013. While Heroin is the most dangerous and addictive drug, causing over 10,000 deaths per year, Fentanyl is on the rise.

Key Takeaways:

  • Eating a balanced diet is a healthy choice, especially a mix of plant and animal based foods
  • Avoid high energy density foods as they do not provide a variety of nutrients a
  • the environment where one eats may have more influence on how food is digested than one might guess, so calm and peaceful is best

"Drug overdoses killed 50,000 Americans last year."



Reference:

//www.nbcnews.com/health/health-news/fentanyl-rises-cause-drug-overdose-deaths-n698331?cid=public-rss_20161224

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3730)


Replacing carbs with protein? Don't overdo it
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Date: December 17, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Replacing carbs with protein? Don't overdo it





Protein has become the dietary supplement that everyone is talking about. With benefits thought to range from building muscle to losing weight, protein powders and bars have become a staple in American society. Specialists are beginning to wonder if getting too much protein in the diet can lead to bad side effects. It is estimated that most American men consume double the daily recommended intake. There are concerns that high protein diets can lead to the development of diabetes and liver disease. They are cautioning people to keep their intake closer to the recommended dosage.

Key Takeaways:

  • The majority of Americans get more than the recommended daily amounts of protein from food and there are no long-term studies to tell us how much protein is too much.
  • Dietary Guidelines for Americans cautioned that some people should “reduce overall intake of protein foods” and eat more vegetables.
  • Protein has achieved a venerated status in the dietary world for everything from building muscle to preventing weight gain. But can you get too much of a good thing?

"A canned protein drink can contain almost as much protein as a 227g steak, and snack bars or a small bag of protein chips can pack more of the macro-nutrient than a three-egg omelette."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.todayonline.com/sports/replacing-carbs-protein-dont-overdo-it&ct=ga&cd=CAIyGmZjNGVlYTM1NDU3YmZmOGU6Y29tOmVuOlVT&usg=AFQjCNHR_rfKldWEgXmnB4ctMv7gqMDRVQ

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3661)


Magnesium Does a Heart Good; Long Live Optimism; Post-Stroke Epilepsy
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Date: December 15, 2016 04:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Magnesium Does a Heart Good; Long Live Optimism; Post-Stroke Epilepsy





Do you get enough magnesium in your diet? Well your heart will thank you if you up the intake in your diet. Getting enough magnesium each day will do your body good. It is important to get enough to limit risk for stroke, heart disease, and heart attack, get it today.

Key Takeaways:

  • A diet rich in magnesium can improve your cardiovascular health.
  • In a recent study, each 100 mg of magnesium intake resulted in a 22% lower risk of heart failure and 7% lower stroke risk.
  • These findings highlight the importance of informing the public on dietary Guidelines to reduce magnesium deficiency-related health risks.

"A general expectation that good things will happen was associated with nearly 30% better survival chances over 8 years across major causes of mortality in an analysis of the 70,000-person Nurses Health Study in the American Journal of Epidemiology."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.medpagetoday.com/Cardiology/Prevention/61963&ct=ga&cd=CAIyGjM5ZjM5OTY2MWYzZGRiYzA6Y29tOmVuOlVT&usg=AFQjCNGxjI752Vu-qMiKqfiThA6ab89KIw

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3653)


World's oldest living person has eaten 3 eggs a day for over 90 years
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Date: November 11, 2016 04:49 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: World's oldest living person has eaten 3 eggs a day for over 90 years





How many eggs do you eat each day? For one woman, who happens to be turning the tender age of 117 soon, eats two every day, as she has for more than 90 years now. She is doing something right with her diet as she still looks amazing. Perhaps there is something about eggs that help us live long lives!

Key Takeaways:

  • And she continued to keep that dietary advice for more than 90 years, meaning she has eaten more than 100,000 eggs.
  • He said that when he first met her she was eating three eggs per day, with two raw eggs in the morning and an omelet for lunch around noon.
  • Currently government recommendations allow for moderate, not restricted, egg consumption, if that's what you want to do. Guidelines are for one egg per day, or about seven whole eggs per week.

"Currently government recommendations allow for moderate, not restricted, egg consumption, if that's what you want to do. Guidelines are for one egg per day, or about seven whole eggs per week."



Reference:

//www.naturalnews.com/055882_eggs_long_life_oldest_living_person.html

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Curcumin Helps Alleviate Depression
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Date: October 26, 2016 08:24 PM
Author: Darrell Miller
Subject: Curcumin Helps Alleviate Depression

Curcumin is a phenolic acid that can be sourced from the cooking spice turmeric. It acts as a powerful antioxidant in humans and protects the body's cells from dangerous free radicals (harmful by-products that are released into the cells during oxygen related reactions). Provisional studies suggest that it may also have many more health benefits. There is also some evidence that curcumin or turmeric may help alleviate the symptoms of certain skin diseases, viral infections, diabetes, colitis, stomach ulcers, and high cholesterol. Once again, the ancient herbal remedy is being celebrated as a modern wonder drug. But perhaps the most promising results have been seen in the use of curcumin to treat depression.

Curcumin2

Curcumin vs. Prozac

If there's one thing Big Pharma fears more than anything else it's competition from the outside. Because herbal medicines have far fewer and less serious side effects than prescription pills, they would be the logical choice - if only they worked as well. Well, there is now irrefutable, ironclad scientific evidence that an herbal remedy is every bit as effective at treating depression as one of the most popular prescription antidepressants.

When researchers with the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India conducted a controlled clinical study comparing the effects of curcumin and Prozac, they didn't expect to make national, even global news. Although the popular herbal remedy is widely used in India, curcumin had never been subjected to rigorous scientific testing for the treatment of major depressive disorder (MDD). The most serious and chronic form of the disease, major or clinical depression affects about 3 percent of population at any given time. The idea that a chemical compound from a popular native spice could compete with Prozac seemed far- fetched to those conducting the study. But after 60 patients diagnosed with MDD were randomly administered curcumin, fluoxetine (Prozac), and a combination of the two, the results spoke for themselves.

With the help of the Hamilton Depression Rating Scale, 17-item version (HAM-D17), researchers determined that curcumin was just as effective as Prozac at treating serious depression. Because the study utilized the latest research tools and followed strict testing Guidelines, it became the first published report that indicated the efficacy of turmeric or curcumin in the treatment of depression. What the report did not take into account, however, were the serious side effects those who take Prozac endure; the most serious of which include anxiety, seizures, racing heartbeat, trouble sleeping, and suicidal ideation.

How Curcumin Treats Depression

Shortly after the results of the aforementioned study made news, researchers started looking for answers. It was not enough for Western scientists to know that curcumin is effective in the treatment depression, they also had to know how. As you might imagine, the how has proved more challenging than the if. This is not at all surprising, since curcumin has diverse biological properties that are difficult to study separately. So, while the mechanism of action is poorly understood, the effects of curcumin intake are well documented, particularly with regard to neurotransmitters.

As their name implies, neurotransmitters send messages to the billions of neurons in the human brain. Some of these neurotransmitters are responsible for regulating brain functions such as mood, memory, appetite, and sleep. Known as "feel-good" neurotransmitters because they help maintain mood balance, dopamine and serotonin play a role in depression. How do we know? For starters, studies have confirmed that people who suffer from clinical depression have consistently low levels of both neurotransmitters.

Once again, we aren't sure how curcumin extract works its magic, but testing has shown that those who take it have higher serotonin and dopamine levels. That fact alone might account for the improved mood those that take the dietary supplement have consistently reported. Although researchers will undoubtedly get to the bottom of this ancient mystery, it enough for most patients to know that curcumin is a safe and effective treatment option.


Related Products

//vitanetonline.com/description/90352/vitamins/Curcumin/

076280903522


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Is Cocoa Butter Good For The Skin? Why?
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Date: March 06, 2014 03:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Cocoa Butter Good For The Skin? Why?

Cocoa butter

cocoa plantDoubtlessly, there are few preferred healthy skin items over cocoa butter and some few that likewise makes you feel great deductively notwithstanding feeling extraordinary because of the way your skin looks so great, but Cocoa butter is good solid skin reinforcement, and for additional data on characteristic healthy skin items with a great experimental foundation. Therefore it is good for the skin.

Reasons to why cocoa butter is good for your skin:

Powdered cocoa butter contains a lot of diverse antioxidants which behave synergistically presenting a massive bothersome resistant to the cost-free radicals which eliminate your skin layer cells along with lead to quick getting older. Therefore, therefore, is it doesn't suitable natural skin care solution.

Let's have a look at which record again. Precisely why your 'ideal' natural skin care solution? In order to solution which question, we need to have a look at precisely what antioxidants tend to be, along with precisely what hot cocoa butter can perform them, along with after that the reason why it is advisable than additional natural skin care merchandise on the market.

Totally free radicals tend to be small substances kinds in the body's fat burning capacity while vitality is generated coming from blood sugar in the mitochondria of each and every cell phone within your body. Fortunately they are shaped simply by experience of toxins including pesticides, along with particularly the several poisonous pieces of cigarette light up. Cigars along with water lines tend to be believe it or not harmful than tobacco, along with filtration system Guidelines make not any difference towards the production connected with cost-free radicals.

What exactly that they do is always to eliminate cells, when they're pores and skin cells you continue to grow older. Your skin layer wrinkles along with dries up, and you begin to take on the style connected with an individual many years over the age of you're. These people try this by way of a procedure often known as oxidation, along with antioxidants can certainly keep the idea. These people reduce the effects of your cost-free radicals, and forestall your skin layer cells coming from getting ruined.

Contents of cocoa

Powdered cocoa butter contains several different antioxidants that can eliminate away from numerous diverse cost-free radicals along with superoxides, as well as hydrogen peroxide. Vitamin e is really a powerful antioxidant -- your strongest of all the so-called antioxidant vitamin supplements in fact, and will quickly eliminate away from hydrogen peroxide along with any oxidizing agent. Others tend to be vitamin supplements A new along with G, however they can not strategy the potency of vitamin E.

Furthermore, it contains phytochemicals (posh title pertaining to place chemicals) including flavanoids which might be also powerful antioxidants. Polyphenols are very effective in neutralizing cost-free radicals, and the hot chocolate mass polyphenols tend to be in particular successful. In fact, hot chocolate butter boasts a greater antioxidant awareness and then possibly blueberries as well as other so-called superfoods.

In order that hot cocoa butter to work, it will email numerous of the pores and skin cells as is possible, that involves do away with the idea properly directly into your skin layer. The epidermis is incredibly absorbent all of which will eliminate cost-free radicals in the reduced absolute depths of the pores and skin as soon as they're created, along with ahead of they are able to do injury.

It is clinically demonstrated which hot chocolate butter will certainly keep pores and skin degradation a result of the harmful consequences from the UV light in the rays of the sun -- UV rays builds cost-free radicals which are very effective in doing damage to pores and skin. Merely go through the influence connected with sunburn! However, there is additional in order to hot chocolate butter than which.

It contains a substantial percentage connected with vitamins as well as lime scale, potassium, magnesium, zinc, manganese, copper along with metal, all of which come in a highly bioavailable style which make them far better which business vitamins. Not just that, though. Furthermore, it contains tryptophan, involved in the development connected with serotonin, your 'feel good' neurotransmitter, and also dopamine along with phenylethylamine, many beneficial materials. It is a mental faculties food as well as food to your pores and skin.

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Melatonin CAn Help You Sleep Better in a natural way
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Date: December 22, 2013 04:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Melatonin CAn Help You Sleep Better in a natural way

sleepMelatonin

If you find that you are not able to sleep on any particular day, then you are not alone who experienced this problem because many other people are also there that face this problem on regular basis. In most of the cases this problem appears due to lack of melatonin hormone that plays an important role in regulation of sleep cycles.

Disturbed Sleep

In case you disturbed your natural sleep cycle because you traveled to some other time zone or you are in work that requires you to work in night, then it can reduce the natural production of melatonin in your body and you may find trouble in sleeping. However, melatonin supplements are available there that can help you sleep naturally. All you have to do is you need to consume it 30 minute before you go to bed.

The best thing about melatonin

Is that it works on almost every individual and within 30 minute of its consumption you start feeling drowsy and you find it impossible to stay awake. After that it take you in some deep sleep where you can see some vivid dream and when you wake up you find yourself completely fresh and energetic. Another great thing about melatonin is that it does not introduce any external chemical in your body to make you feel sleepy, but it does it in a natural way and that’s why you don’t even need a prescription for using it.

However, it is very important that if you have any particular health problem or if you are pregnant, then it is suggested that you should consult with doctor before consuming melatonin. Other than this, it is also very important that you should consume it with Guidelines only because if you take it more than suggested quantity you may feel sleepy and tired for rest of your day as well.

References:

  1. //voices.yahoo.com/the-melatonin-miracle-help-sleep-but-whats-67011.html
  2. //health.howstuffworks.com/mental-health/sleep/basics/melatonin-sleep.htm
  3. //www.sleepfoundation.org/article/sleep-topics/melatonin-and-sleep

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Benefits of magnesium chelate
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Date: June 23, 2012 02:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of magnesium chelate

According to various authority websites on the internet magnesium chelate usage can result in positive effects for the human body. The fact is that people will need to balance its use and not take too much, because otherwise, like with any overdose, they will be in for some side effects.

The way it works

There are basically two types of magnesium out there and they number the insoluble and the soluble version. The latter gets absorbed by the human body very well, but when it comes to the former, it will take some time until the body manages to dissolve and absorb it. One of the benefits of using the soluble version is that the body can absorb it very easily and after that supplement the entire system, maintain a healthy level of magnesium and improve the immune system. For adults it's recommended they would take four hundred milligrams of magnesium on a daily basis, depending on their size and gender.

Positive Effects

The truth is that magnesium chelate is an amino acid that occurs naturally in the human body. Some of its positive side effects number improving the normal functioning of the heart, of the muscles, of the bones and also an improvement in the bloodstream of magnesium deficient individuals. There are also many people who choose to take magnesium in order to improve the quality of their sleep by calming down their entire nervous system.

On top of that, magnesium also showed positive effects in helping the body absorb potassium, calcium, decrease the risk of heart attacks, maintaining a low blood pressure and reducing high blood pressure.

Diabetes is a lifelong disease, but studies and experiments have shown that taking magnesium people will be able to defer it. Those who have a deficiency in this element will oftentimes feel weak, deal with nauseas and experience fatigue. In some cases it can lead to an impaired cardiovascular function and even seizures.

For a healthy cardiovascular function and strong bones, calcium is a must for everyone. More to that, if an individual has a low magnesium level this can be mainly because of a low blood calcium.

Guidelines for taking magnesium chelate

Many health institutes recommend that adults (women) who are between nineteen to thirty years old will take three hundred and ten milligrams of magnesium on a daily basis. After the age of 30, they should take three hundred and twenty mg per day. In regards to men between 19 and 30 years old and even beyond that, they should take four hundred mg per day and four hundred and twenty mg respectively. In case of an overdose (even though it's very rare) people will experience gastrointestinal distress and to avoid it, they should strictly follow the recommended dosage.

As people can see, taking magnesium can be quite beneficial for the overall healthy functioning of their body, yet as with any type of drug out there, taking too much of it can have a few undesired side effects.

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How Do I Use Phytoestrogen And Progesterone Creams For PMS?
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Date: September 22, 2011 11:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Do I Use Phytoestrogen And Progesterone Creams For PMS?

Overview

If you are a guy who had encountered women you probably would have heard about PMS. It is something that we as men are familiar with because often times, about once a month our female acquaintances would let us know that they should be allowed to act silly and have their way for the next few days all because they are experiencing PMS but is there truth to it? Let’s try to take a more scientific approach because my guess is, it is more serious than we know.

PMS

Premenstrual syndrome (PMS) is defined by strong and consistent mood swings, tender breasts, fatigue, depressions, food cravings and irritability just to name some of the more common symptoms. Commonly this peaks around the late 20’s and early 30’s for females and it is a serious issue. It is not the kind of juvenile reason for tantrums that young female kids might lightly throw around. These symptoms can cause serious discomfort and many changes in the sufferer’s lives and at times in certain months it will be pretty intense and unnoticeable in some. It also happens in a predictable pattern which is one upside to allow the patient to prepare for it and can figure out certain ways to counter the effects so as to not allow PMS to take control of your life.

Phytoestrogen And Progesterone Creams

First off let look at some details about these substances. Phytoestrogen are chemicals that are derived from plants and have the primary property of having the ability to mimic estrogen in the human body which is the primary sex hormone in women. Estrogen on the other hand is the real thing and is a hormone manufactured primarily in the ovaries with an essential responsibility of initiating and maintaining proper menstrual cycles in women.

Although this hormone can also be found in the male’s body we produce it at a lesser degree. Studies have shown that estrogen is an important factor in women’s reproductive cycles unlike men which does not really have much use for it and aims to keep the levels of this hormone down as it may cause more feminine bodily changes in men. With women however, supplementation with estrogen has been used to treat reproductive cycle issues so it is no surprise that these hormones are being incorporated into cream products to aid in PMS relief and how you use it depends on your specific cycle.

Some common Guidelines is to use of about 100 to 200mg a day and it terms of when, it shall depend on the length of a female’s cycle. As a general rule though it should be taken 14 days prior to ovulation if the specific ovulation date is not known as ovulation starts fourteen days before bleeding starts. If no ovulation happens or you don’t have a period, use a 28 day cycle as a guide and choose any day to start. It is important that this is done before ovulation so it does not interrupt the body’s natural process of ovulation and hormone production.

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Best Probiotic Supplements For A Healthy Intestinal Tract
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Date: December 09, 2010 05:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Probiotic Supplements For A Healthy Intestinal Tract

Best Protiotic Supplements

It is very important to find the best probiotic supplements, but before you know how to choose the best probiotics, it is important to know what probiotics actually are. Probiotics are bacteria molecules that are beneficial and can also be in the form of yeast. These molecules are live and have been said to probiotic picture act beneficially by some one who uses them in moderation. The word “probiotics” comes from the word pro (for) and bios (life) so this gives the impression that they are increasingly important supplements that can be used in everyday life, which is true.

Probiotic supplements have been known to help with lactose intolerance, the prevention of colon cancer, lowering cholesterol, lowering blood pressure, improving the immune system and preventing harmful bacteria growth under stress, among other beneficial factors.

You may associate yourself with one of the above conditions and are therefore wondering what the best probiotic supplements are for you to use. Everybody’s needs are different so doses vary from person to person. In persons affected with lactose intolerance, the lactic acid bacteria can be digested to convert lactose into acid and then it is easier to digest. This is just a small example of the hundreds of probiotics out there that deal with many conditions.

When it comes to choosing a probiotic there are a few Guidelines to follow. Keep in mind that it varies for different conditions and the best probiotic supplements may not be suitable for every person. NOW - Probiotic-10 - 50 Billion 50 Vcaps

Before you turn to probiotics, it is important to know that you are getting enough bacteria. If you are getting less than 10 million live bacteria then you probably want to increase your bacteria intake so that it meets this standard.

It is also important, when looking for the best probiotic supplement, that you look at the ingredients. Generally, it is good if a probiotic contains bacteria from the Lactobacillus family, otherwise there are obviously different bacteria’s that help with different conditions. Before you purchase a probiotic, be sure to do research on what you are specifically looking for or ask your doctor to recommend a good probiotic.

In addition to the probiotic supplement having bacteria, it should also house FOS, the preferred food for friendly bacteria. This ensures that the probiotic will operate on an optimum level, as FOS nutrition helps probiotics grow stronger and function better. This is especially important with probiotics that are taken for irritable bowel syndrome and chronic diarrhea.

Those who have been on antibiotics need probiotic friendly bacteria. Antibiotics destroy friendly bacteria. Probiotics can be used by people and children who want to maintain a healthy lifestyle and want to have a strong immune system and healthy well balanced intestinal tract.

Have you had your Probiotics Today?

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Colostrum
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Date: June 18, 2009 10:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Colostrum

After going through puberty, our bodies gradually decrease in the production of immune and growth factors that generally combat disease. After losing these vital components, we are much more susceptible to the aging process, which shortens our life expectancy. Colostrum and its other components have the ability to fight off bacterial and viral invaders as well as stimulate tissue repair, which is something that becomes increasingly vulnerable as we age by boosting the immune system. For all of these reasons, it is important for an adult to supplement with colostrum.

Colostrum should be collected during the first 24 hours after birth. Also, a colostrum supplement should be processed in a USDA licensed facility. This insures the consumer that USDA Guidelines are being followed. Additionally, consumers should make sure that products labeled Colostrum are actually 100% colostrum, not colostrum or concentrates of milk whey. Lastly, colostrum that is mixed with other supplements or herbs and additives may have a diluted colostrum concentration, which means the benefits you could obtain from this supplement may be compromised.

Even though colostrum has no interactions with drugs, side effects may be experienced from a cleansing or healing crisis, which is a necessary but somewhat inconvenient and adverse result. Fortunately, once the healing crisis is complete, you will feel substantially better and in good terms of health. Mediations may need to be re-evaluated by your medical profession for dose and need.

Although colostrum is generally believed to be very safe for those mothers who are pregnant and nursing, one should probably ask their medical professional prior to taking colostrum or its specific agents while they are pregnant. Just like any other supplement or drug, it is better to be overly safe and check with a healthcare provider before jeopardizing a pregnancy.

Colostrum is recommended specifically for children who have not already received the mother’s breast milk, as breast milk would have already provided the benefits that would be obtained through colostrum supplementation. Those children with flu, colds, bacterial or viral infections, or children who have been on long or short-term antibiotics or other drugs are good candidates for colostrum supplementation. Therefore, colostrum supplementation is safe and may be recommended for these types of children.

Many people wonder if colostrum products can pass on mad cow disease. At this time, no case of mad cow disease has been reported in the United States. With awareness of the disease being so high, it is extremely unlikely that one would contract mad cow disease from a colostrum product.

The overall supplementation of colostrum and other products that contain derivatives of colostrum has been shown to extremely safe. Additionally, it has been shown that colostrum is equally effective, whether it be taken by injection or by mouth. It has also been shown that the long-term administration of colostrum preparation is very safe to the human body. Because infants and the elderly are the two main groups that are especially at risk for infections, many people may wonder just how safe colostrum products are for these two groups of people. Not only is oral administration safe, it is also very effective and easily accepted by both of these groups.

Colostrum is available in capsule of tablet forms at your local or internet health food store. Look for name brands like Kal and Source Naturals to ensure quality and purity of the product you purchase.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Colostrum is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Multiple Vitamins
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Date: February 04, 2009 09:17 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Multiple Vitamins

It has been announced that it pays to take your vitamins, as the American Medical Association has completely reversed its previous anti-vitamin stance after twenty years and is now encouraging all adults to supplement daily with a multiple vitamin. After this decision, a review of 38 years of scientific evidence has convinced the Journal of the American Medical Association (JAMA) to rewrite its policy Guidelines regarding the use of vitamin supplements.

It is common knowledge that today's diet is not providing sufficient nutritional value to keep chronic diseases at bay. Although nutrient intakes in North American are generally sufficient to avoid overt vitamin deficiencies, sub-clinical deficiencies are extremely common. Most vitamins and minerals come mainly from fruits and vegetables, causing us to need at least five daily servings of each. Studies have found that the number of servings of fresh fruits and vegetables is well below the recommended fiver servings per day, with the intake of dietary iron, folic acid, and calcium being significantly below recommended levels for adolescent girls.

Not many people know that cardiovascular disease is a problem that has been cultivated by modern society, with the first report on cardiovascular disease in America being published in 1912. At that time, the disease was so rare that it took years to find. In less than 100 years, the changes to our lifestyle, environment, and to the food we eat have made cardiovascular disease the number one killer in North America.

A groundbreaking report on July 13, 2000 tied the development of most cancers to lifestyle and the exposure to environmental and occupational risk factors. Although a genetic influence was not negated, as it appears to account for about 30% of total cancer risk, the findings placed the blame on poor dietary habits, smoking, alcohol consumption, lack of exercise, and exposure to environmental toxins. It has been recommended that a diet made up of plant-based foods which include vegetables, fruits, and grains is essential.

Stroke, the third-leading cause of death in the most developed countries for decades, occurs when blood flow to the brain is cut off due to a thrombotic event in one of the major arteries feeding the brain. A major cause of disability among adults and a principal factor in late-life dementia, small strokes can often go unnoticed. Because hypertension is the major cause of stroke, potassium and its blood pressure-lowering abilities are often helpful. Additionally, nutrients such as folic acid, bioflavonoids, polyphenols, and assorted antioxidants play an important role. The consumption of citrus fruit juices that contain high levels of vitamin C, and cruciferous vegetables like broccoli, cabbage, Brussels sprouts, bok choy, and cauliflower give protection against stroke.

Not only are we not eating enough of the proper food groups, the foods we do eat are often short in vital nutrients and high in calories. Nothing can replace the value of a diet that is carefully balanced. However, in today's high-stress world, we often face a absence of physical activity and a surplus of meals on the run, consisting of fast-food and processed foods that lack nutritional value. We should never neglect the importance of a well-balanced diet that is high in fruits and vegetables and we should make every opportunity to eat as close to the earth as possible.

Unfortunately, in today's fast-food world, it is hard to get away from the high-calorie, low-nutrition, over-processed, corporate food culture. If you value your health, it makes sense to take the extra step and start supplementing your diet with nutritional supplementation, as it is your personal health insurance to help you age gracefully. Stop into your local or internet health food store and look for a good multiple vitamin supplement to help boost your current diet.

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Flaxseed Oil
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Date: December 23, 2008 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Flaxseed Oil

Although it is important to stress that the fatty acids found in flax are essential, flax also contains substances called lignans. Lignans are special compounds that demonstrate impressive health benefits, as they seem to be responsible for assisting the immune system in many ways, along with helping to prevent some types of cancers.

Because flax contains lignans, it is an even more beneficial to the body when consumed in this form. Flax is one of the most abundant sources of lignans, a type of phytoestrogen that interferes with estrogen metabolism in animals and humans. This property gives lignans the ability to help in the prevention of both fat and hormone-sensitive types of cancer. Lignans also benefit the body by providing antibacterial, antifungal, and antiviral activity that helps the immune system to function optimally.

All of the benefits of flax are still yet to be known, but it has been established that flax is also a good source of fiber. There have been several studies which confirm that flaxseed can be a cholesterol-lowering agent similar to oat bran, fruit pectin, and other food ingredients that contain fiber. Because flax packages both omega-3 fatty acids and soluble fiber together, it presents two ingredients which provide healthy blood lipid patterns. Flaxseed contains beneficial amounts of both soluble and insoluble fiber, giving it potential cancer-fighting ability especially in colon cancer.

When selecting a healthy diet, it is important to consider your sources of essential fatty acids. Essential fatty acids are fragile and easily damaged by air, high temperatures, and food processing, so you are unlikely to get all of the EFAs that you need, even if you are careful to use vegetable oils for cooking. Most of the oil that we consume today has been heavily processed, which damages essential fatty acids. When choosing flax oil, you’ll want to take into account the same considerations, looking for oil that has not been damaged by processing and is packaged to block all light from contact with the oil.

Not all flax oils are the same, with there being a great deal of variation in quality and purity as a result in differences of how the oil is expressed. Most flaxseed oils are mechanically pressed out through an expeller, in which great amounts of heat and pressure can be generated. The higher the temperature, the better the yield of oil, but the lower the quality of oil. Many manufactures willingly sacrifice quality for quantity. The best way to measure the quality of oil is by taste, with the degree of bitterness being a close approximation of the level of lipid peroxides. The best source of high quality flaxseed oil can be found in health food stores where inventory turnover is highest.

Some good Guidelines to go by in selecting a good flaxseed oil include: making sure the flaxseed oil is derived from 100% certified organic flaxseed; making sure the oil is as fresh as possible and not past the expiration date; making sure that the oil is expeller-pressed or cold pressed; using flaxseed oil that is high in lignans to gain the most benefit.



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Red Yeast Rice
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Date: August 04, 2008 04:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Red Yeast Rice

Many natural substances that are capable of lowering blood fats and cholesterol levels that are potentially harmful have emerged. No one is suggesting that there is a magic pill that will promote healthy cholesterol levels, but nature has provided us with some specific compounds that are capable of enhancing both dietary and lifestyle changes in order to improve cardiovascular health. One of the most impressive of these compounds is that of red yeast rice, which is a fermented food substance that has been traditionally used for its red-coloring abilities in meats and other foods. Additionally, red yeast rice offers some extremely beneficial therapeutic effects, as it is the source of certain compounds that can successfully reduce cholesterol.

Pharmaceutical companies have been making cholesterol lowering drugs for many years, but natural supplements are now available which offer the consumer a way to lower cholesterol in natural way. This is extremely good news for those people who are suffering from moderately elevated cholesterol levels and is looking to avoid synthetic drug preparations and the side effects that follow.

Most of us are now aware that high serum cholesterol level is what predisposes us to cardiovascular disease along with other degenerative conditions. Learning how to control our cholesterol levels, especially the LDL and blood triglyceride levels, while keeping HDL cholesterol at desirable levels can be an extremely frustrating task. By decreasing our consumption of animal fats and certain types of oils, eating more fiber and taking prescription drugs or natural alternatives, we can easily accomplish our goal.

Dietary changes should be targeted first, but turning to cholesterol-lowering prescription drugs has both its pros and cons. Pharmaceutical preparations come with considerable side effects. Some of the drugs that are most effective contain enzymatic inhibitors that prevent the synthesis of cholesterol. Red yeast rice accomplishes the same enzyme inhibition but is considered a natural alternative that safely promotes healthy serum cholesterol levels.

Coronary heart disease refers to the damage that is done to the heart when the coronary arteries become blocked or narrowed because of a buildup of plaque or oxidized cholesterol. When cholesterol buildup breaks off and lodges in the heart or brain, this causes a heart attack or stroke. An extremely common disorder of developed nations, coronary heart disease causes more deaths in the US than any other disease. Many people who die from heart disease are ironically in otherwise good health.

High blood pressure, which is a related disorder, is similar in the fact that both can be a silent killer. The symptoms of coronary heart disease include impotence, heart attack, or stroke. Although the mortality rates from coronary heart disease have declined over the last twenty years, the reason for this decline is shown to be the better medical technology that is available. Claiming more than one million deaths every year, coronary heart disease is still a major issue facing the American society.

In order to help us prevent heart disease, we have been given many dietary Guidelines. However, many of us are not motivated enough to make the dietary changes that could literally save our lives. The major causes of coronary heart disease include obesity, smoking, alcohol, high protein and high saturated fat diet, lack of exercise, high blood pressure, high cholesterol levels, and a genetic predisposition.

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Regulating Blood Pressure Naturally
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Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

Regulating Blood Pressure Naturally

 

High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.

In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.

In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.

Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.

 

Blood pressure Guidelines from the National Heart, Lung, and Blood Institute.

Category

Systolic (mm/Hg)

Diastolic (mm/Hg)

Result

Normal

Less than 120

And Less than 80

Excellent!

Prehypertension

120-139

Or 80-89

Make changes in eating and drinking habits, get more exercise and lose any extra pounds.

Hypertension

140 or higher

Or 90 or higher

You have high blood pressure. Talk to your healthcare professional on how to control it.

 

Q. What exactly is blood pressure?

A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”

 

Q. What is considered high blood pressure?

A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.

However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.

Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.

To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.

For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.

 

Q. What courses high blood pressure?

A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:

 

Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.

 

Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.

 

Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.

 

Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.

 

Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.

 

Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.

 

Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.

 

As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.

 

Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.

 

Q. What are the blood pressure numbers I should see?

A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.

 

Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?

A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.

However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.

Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.

Let’s take a look at each:

Stevia leaf extract

Supports healthy blood pressure levels according to clinical studies.

Hawthorn extract

Supports the heart and balance sodium and fluid levels.

Olive leaf extract

Scientifically shown to support healthy blood pressure.

Dandelion leaf

Helps reduce fluid retention

Lycopene

Clinically shown to support arteries, circulation and heart health.

 

Stevia:

Stevia (Stevia rebaudiana) originated in South America, and is often used as a sweetener. Glycosides in stevia, particularly stevoside, give the plan its sweet flavor 0 anywhere from 100 to 200 times sweeter than sugar.

The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.

In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.

And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!

Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.

A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.

 

Hawthorn extract:

Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.

The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.

The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.

And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.

Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.

Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.

 

Olive leaf extract:

Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.

But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.

 

Dandelion leaf extract:

Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.

Medicinally, dandelion has been used for centuries, dating back to ancient Greece. Leaves intended for medicinal use are harvested before flowering, to ensure the most nutrients.

They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.

The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.

 

Lycopene:

If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.

And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.

So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.

 

Q. What can I expect taking this herbal combination?

A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.

When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.

 

Tips for Accurate Blood Pressure Monitoring:

-Relax for about 5 to 10 minutes before measurement.

-If you have just come inside from cold outdoors allow yourself to warm up.

-Remove tight-fitting clothing and jewelry.

-Unless your physician recommends otherwise, use left arm to measure pressure.

-Sit, don’t stand.

-Remain still and do not talk while using the monitor.

 

Q. Are there any side effects?

A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.

 

Conclusion:

High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.

 

In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.



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Lower Cholesterol Naturally!
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Date: October 06, 2006 09:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lower Cholesterol Naturally!

Because of organizations like the American Heart Association (AHA), we’ve learned a lot about cholesterol and how it affects our health. Thanks to these educational organizations, we know that high cholesterol levels can increase our risk for heart attacks and strokes and, by lowering these levels, we reduce these risks as well as keep our hearts and blood vessels healthy. We also know that our cholesterol levels can be improved through exercise, diet, and weight loss.

Although we’ve learned a lot through these educational organizations, there are still a few misconceptions about cholesterol. One of these being that not all cholesterol is harmful. There are both “good” and “bad” forms of cholesterol and a good balance between the two is what is needed for a healthy heart. Because so much emphasis is placed on lowering “bad” cholesterol levels, not enough attention is paid to the benefit of raising “good” cholesterol levels (HDL). Research states that raising HDL levels can provide even greater protection against cardiovascular disease than just simply lowering “bad” cholesterol levels. By raising HDL levels by simply 1%, the risk of heart disease can be lowered by 2% in men and 3% in women. Many studies have shown that low HDL cholesterol levels are an independent risk factor in heart disease. This is extremely important because we’ve learned that despite efforts to change a person’s diet and exercise habits, some people’s cholesterol levels are still unhealthy.

Prescription drugs to lower cholesterol are now available and have been proven by multiple studies to be very successful. The statins’ effectiveness in reducing LDL (“bad”) cholesterol has produced highly significant reductions in heart attacks and strokes. Although these medications do lower cholesterol levels, their side effects must be considered. Statin drugs can cause liver irritation, reduce CoQ10 levels in the body, are associated with myopathy, and are even linked to a rare and sometimes fatal condition called rhabdomyolysis. These drugs also have a relatively small effect on good (HDL) cholesterol levels. Thankfully, there are safe and effective solutions available that can help you manage your cholesterol levels naturally. However, first we must review what we know about cholesterol and heart disease.

Cholesterol is a fat-like substance needed to help digest fats, strengthen cell membranes, make hormones and insulate nerves. Although it is found in every cell of the body, cholesterol is mainly made in the liver, as well as cells lining the small intestine. Even though our bodies make all the cholesterol we need, we also get cholesterol from the foods we eat, such as egg yolks and organ meats. All foods from animal sources contain cholesterol, while plant derived food, including peanut butter and avocado, contains no cholesterol at all.

Cholesterol is important to many functions of the body. However, too much cholesterol in the bloodstream is extremely dangerous. After blood cholesterol reaches high levels, it builds up on the artery walls, and thus increasing the risk for blood clots, heart attack, and stroke. If the cholesterol clogs any of the coronary arteries, the heart’s supply of oxygen and nutrients will diminish, resulting in coronary heart disease, angina, or even heart attack.

Because cholesterol and other fats can’t dissolve in the blood and thereby can’t travel on their own, they have to be transported to and from the cells by lipoproteins. The two major lipoproteins are low density lipoproteins (LDL or “bad cholesterol) and high density lipoproteins (HDL or “good cholesterol”) LDLs carry cholesterol throughout the body to the cells and cause artherosclerosis by clogging up our arteries with fat. On the other hand, HDL prevents the fat buildup by carrying it away from the arteries and to the liver where it can be eliminated. Although high levels of LDL are associated with cardiovascular disease, high HDL can drastically reduce your risk of heart disease. As a result, the AHA has established three Guidelines to keep your heart healthy: HDL levels about 40 for men and above 50 for women, LDL levels between 100 and 159, and a total cholesterol (HDL and LDL) of under 200.

Triglycerides are fats used as fuel by the body and a source for metabolism. These levels can fluctuate easily but increased levels are almost always a sign of too much carbohydrate and sugar intake. High amounts of triglycerides make the blood less capable of transporting oxygen and are another factor for cardiovascular disease. Thankfully, the HDL and LDL blend mentioned earlier can safely and effectively lower triglyceride levels.

It has been shown that high levels of HDL cholesterol are inversely related to coronary artery disease risk. However, what people do not know is that there are different subtypes of HDl, including HDL-2 and HDL-3. HDL-3 is produced by the liver and intestines and is responsible for scooping up free cholesterol from the blood vessel walls. The cholesterol carried by HDL-3 is chemically modified, forming a larger-sized subtype, known as HDL-2, or “mature HDL.” HDL-2 transports cholesterol to the liver for processing and elimination, and its molecules are then recirculated in the blood stream. Research has shown that HDL-2 provides more heart-protection because it moves the cholesterol away from arterial walls, and holds a greater number of receptor sites which allows it to carry a larger amount of cholesterol to the liver.

Although many prescription medications have been developed to lower bad cholesterol, there are very few medications that target good cholesterol. Therefore, patients with naturally low HDL cholesterol, who can not alter these levels through diet and exercise, have limited medical options to reduce their risk of heart disease. Multiple nutrients have been clinically shown to favorably alter good cholesterol levels including: vitamins C, E, B6, B12, niacin, folic acid, magnesium and selenium, with protein-building amino acids, powerful antioxidants such as coenzyme Q10, alpha lipoic acid, N-acetyle cysteine, and policosanol, and extracts of hawthorn, garlic, grape seed, and soy isoflavones. Although this HDL-boosting combination does not result in a significant reduction in LDL, antioxidants found in this formulation can help stabilize LDL and prevent build up in the arterial wall.

This formula combines essential vitamins and minerals, at levels recommended by the American Heart Association. It contains amino acids, antioxidants, and botanicals that have all been used safely for years. No serious adverse effects have been found following supplementation and the combination is safe to use with statin drugs.

Plant sterols, found in nuts, vegetable oils, corn, and rice are structurally similar to cholesterol and are able to block its absorption. Each day the liver receives about 800 mg of cholesterol from intestinal absorption through receptor sites. After entering these channels, the cholesterol is absorbed into the bloodstream. Since plant sterols look similar to cholesterol, they fit perfectly into these receptor sites and block the absorption, which allows the cholesterol to remain in our intestines where it can eventually be excreted. A large amount of plant sterols reduces the amount of cholesterol transported from the intestinal tract to the liver. This cholesterol reduction causes a decrease in LDL levels.

Even if a person does not have high cholesterol levels, reducing bad and raising good cholesterol greatly reduces their risk for ever developing chronic heart disease. Due to side effects, physicians do not normally prescribe statin drugs to people without actual heart disease of high LDL cholesterol levels. Instead, they recommend dietary changes. The HDL-boosting combination and LDL-lowering pantethine and plant sterols blend can effectively help people with heart disease, uncontrolled cholesterol levels, high triglyceride levels, or people who just want to improve their heart health.



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Remifemin symptomatic relief, scientifically supported*
TopPreviousNext

Date: August 26, 2006 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Remifemin symptomatic relief, scientifically supported*

Remifemin

 

Symptomatic Relief, Scientifically Supported*

 

The only RemiSure black cohosh

 

Unique to Remifemin® - Exclusive standardized isopropanolic black cohosh extract, subject of over 90 scientific papers.

Proven Effective – The most clinically studies natural intervention for menopausal symptoms with over 40 years of use worldwide*

 

  • Relief from hot flashes, night sweats, mood swings, irritability, and related occasional sleeplessness*
  • Particularly in women in early stages of menopause*

 

Safe – Completely hormone free

 

  • Works naturally without plant-based estrogens that can affect breast and uterine cell growth
  • Can be used safely by women with a history of breast cancer who cannot take estrogen

 

Efficacy

STUDY DESIGN

BENEFITS

DOSAGE

REFERENCE

1. Twelve-week, randomized, multicenter, double-blind clinical trial comparing the efficacy and tolerability of Remifemin® in the treatment of climacteric complaints compared with placebo.  The primary efficacy measure was the change from baseline on the Menopause rating Scale 1.

·          Remifemin® effectively relieved menopausal symptoms, particularly in women in the early stages of menopause*

·          Most significant reduction was in hot flash occurrence*

·          Other symptoms resulting in significant reduction include: psyche (irritability and memory), and atrophy (vaginal dryness)*

·          No significant adverse effects reported

40mg qd

Osmers R, et al. Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms.  Obstet Gynecol. 2005 May; 105(5):1074-83.

2. A review of 29 randomized controlled trials of complementary and alternative therapies for menopausal symptoms.

·          Black cohosh is one of the only herbal remedies shown to be effective for menopausal symptoms, especially hot flashes*

 

Kronenberg. F. Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med. 2002 Nov 19;137(10:805-13.

3. Four-week, pilot study, open clinical trial of menopausal women with hot flashes, including women with a history of breast cancer.

·          Remifemin® reduced mean daily hot flash frequency by 50% after 4 weeks*

·          Overall, participants reported less trouble with sleeping, less fatigue, and fewer night sweats* 

·          No participants stopped therapy because of adverse effects

40mg qd

Pockaj BA, et al. Pilot evaluation of black cohosh for the treatment of hot flashes in women.  Cancer Invest. 2004;22(4):515-21

4. Double-blind study involving the use of Remifemin® in women ages 43 to 60 with menopausal complaints lasting 6 months.

·          Majority of woman saw a 70% reduction of physical and emotional symptoms after 12 weeks, including hot flashes, night sweats, mood swings, and irritability*

·          Significant improvement was noted after 4 weeks use*

·          Remifemin® works safely and effectively to treat menopause symptoms without affecting hormone levels or vaginal cytology (pap smear)*

40mg qd

Liske J, et al. Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizome): a 6-month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med. 2002 Mar; 11(2): 163-74

5. Double-blind, 6 month study in hysterectomized women under 40 with at least one ovary.

·          As effective as estriol, conjugated estrogens, or hormone combinations at decreasing physical menopausal symptoms at 4, 8, 12, and 24 weeks*

4mg dry extract bid (equivalent to 2 tablets Remifemin® bid

Lehmann-Willebrock E, Riedel HH. Clinical and endocrinologic studies of the treatment of ovarian insufficiency manifestations following hysterectomy with intact adnexa. Zentralbl Gynakol. 1988; 110(10):611-8

 

6. Women aged 45 to 58 with menopausal complaints were studied in a double-blind, 12 week, placebo-controlled trial.

·          Remifemin® decreased physical symptoms of menopause by approximately 60% (Kupperman menopausal indeed)*

·          Daily hot flashes decreased by 86% in the Remifemin® group(from 4.9 to 0.7 per day)*

·          Emotional complaints were also dramatically reduced*

4mg dry extract bid (equivalent to 2 tablets Remifemin® bid

Stoll W. Phytopharmacon influences atrophic vaginal epithelium: Double Blind study – Cimicifuga vs. estrogenic substances. 1987.

 

Safety

STUDY DESIGN

BENEFITS

DOSAGE

REFERENCE

7. in vitro, MCF-7 cell culture model to determine estrogen-agopnist and antagonist activity of commercially available herbal menopause preparations containing red clover, soy black cohosh, or a combination of herbs.

·          Remifemin® had no effect on estrogen-sensitive cells in vitro.

·          Results suggest safety for women with a history of breast cancer who cannot take estrogen.

In Vitro(10^3-10^5 dilutions)

Bodinet C, Freudenstein J. Influence of marketed herbal menopause preparations on MCF-7 cell proliferation.  Menopause. 2004 May-Jun;11(3):281-9.

8. Six-week, in vivo investigation of Remifemin®’s ability to stimulate estrogen-receptor positive cells in an animal model

·          No estrogen stimulating effects were found.

·          Prolactin, follicle-stimulating hormone, and luteinizing hormone levels were unchanged.

0.714m 7.14 or 71.4mg/kg/day

Freudenstein J, et al. Lack of promotion of estrogen-dependent mammary gland tumors in vivo by an isopropanolic Cimicifuga racemosa extract. Cancer Res. 2002 Jun 15;62(12):3448-52.

 

 

 

9. Comprehensive review examining all published literature pertaining to pre-clinical and clinical safety of various forms of Cimicifuga racemosa, as well as FDA and World Health Organization (WHO) adverse event reporting systems, monographs, compendia, internal unpublished data from a major manufacturer, foreign literature, and historical, anecdotal report.

·          Uncontrolled reports, postmarketing surveillance, and human clinical trials of more than 2,800 patients demonstrate a low incidence of adverse events (5.4%).

·          Of the reported adverse events, 97% were minor and did not result in discontinuation of symptoms, and the only severe events were not attributed to Cimicifuga treatemtn.

·          Confirms the safety of specific Cimicifuga extracts, particularly isopropanolic preparations (Remifemin®), for use in women experiencing menopausal symptoms and as a safe alternative for women in whom estrogen therapy is contraindicated *.

Various

Low Dog T, et al. Critical evaluation of the safety of Cimicifuga racemosa in menopause symptom relief. Menopause: Journal of the North American Menopause society. 2003;10(4):299-313.

 

Relevant Reports and Guidelines

ORGANIZATION

PUBLICATION

EXCERPT OF KEY CONTENT

American Botanical Council

The ABC Clinical Guide to Herbs including a black cohosh monograph issues September 2002

“Of 10 clinical studies, including a total of 1,371 participants, nine of these studies demonstrated positive effects for menopausal symptoms.  Numerous clinical trials with varied methods and designs have been conducted on the standardized isopropanolic/ethanolic extract of black cohosh root, Remifemin®, from 1981 to the present.”

National Institute of Health

Questions and Answers About Black Cohosh and the Symptoms of Menopause issued October 2002

“Other preparations of black cohosh have been less well studied than Remifemin® …black cohosh is used primarily for hot flashes and other menopausal symptoms.  A number of studies using various designs have been conducted to determine whether black cohosh affects the menopausal symptoms… To provide more definitive evidence on the effects of black cohosh on menopausal symptoms, NCCAM is funding a 12-month, randomized placebo controlled study to determine whether treatment with black cohosh is effective in reducing the frequency and intensity of menopausal hot flashes.”

The North American Menopause Society

Alternatives to Hormone Replacement Therapy: Suggestions for the North American Menopause Siciety issued July 2002

Reseach suggests that mild hot flashes can be relieved by consuming a serving of soy foods daily or taking a supplement of black cohosh.”

 

Responding to the need for alternative menopausal symptom relief*

 

Natural, Safe alternative to HRT for menopausal symptoms*

 

  • Remifemin black cohosh was as effective as HRT for menopausal symptoms*

 

Superior Manufacturing Quality

 

  • Prepared according to Good Manufacturing Practice (GMPs) which ensure delivery of a product with the highest quality and consistency
  • Convenient dosing – one 20mg tablet twice a day (one in the MORNING, one in the EVENING)
  • 100% RemiSure black cohosh – not a combination of herbs

 

VitaNet Recommends Remifemin

 

  1. Remifemin unique standardized isopropanolic extract is the most widely studied and clinically tested natural alternative treatment for relief of menopausal symptoms.
  2. Remifemin black cohosh proven effective in reducing menopause and peri-menopause symptoms, including hot flashes, right sweats, mood swings, and irritability without estrogenic effects.
  3. Used safely by millions of patients worldwide for over 40 years.  Remifemin has been proven effective and is the most clinically studied natural intervention of menopause.
  4. Remifemin doesn’t have the side effects that are experienced with hormonal drugs prescribed for the relief of menopausal symptoms.

 

Lit source: Enzymatic therapy.

*this statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treate, cure, or prevent any disease.



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What are you really Getting?
TopPreviousNext

Date: August 21, 2006 05:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are you really Getting?

 

Supplement labels can be confusing!

 

The list of ingredients on some supplement labels can tax the mind of even a Ph.D. in nutrition!  What’s worse, although labeling laws exist to counter misleading and non-uniform labeling, confusing and deceptive labeling, confusing and deceptive labeling practices continue to abound.  Here’s some help to aid you in making better sense of supplement labels.

 

1.Begin at the Bottom

 

The supplement facts panel on the label of every nutitional supplement sold in the U.S. tells you about active ingredients in a product. Before analyzing this information, look beneath the panel, where the OTHER INGREDIENTS are listed.  Here, at a glance you can begin to spot a questionable product.  Synthetic colors, flavors, preservatives, or the absence of certain information, are early warning signals. 

 

Poor Label

 

 

Good Label

1.other ingredients: Cellulose, stearic acid, sucrose, sodium, silicoaluminate, talc, titanium dioxide, mineral oil, FD&C red #40, FD&C yellow, aluminum lake, polysorbate 80.

  1. other ingredients: Cellulose(capsule), vegetable magnesium state, silica.
  2. this product contains no gluten, wheat, yeast, eggs or dairy, no synthetic colors or flavors , and no toxic levels of lead or other heavy metals.
  3. Lot# 123456

Expires: 01/08 or use by: 01/08

 

 

  1. Other Ingredients: supplements can be natural only by degree, since their manufacture often requires the use of binders, flowing agents and other items.  Such materials may come from natural and artificial sources. They must be listed in descending order by quantity.
  2. Contains No / May Contain:  Sometimes, supplements are derived from sources that could cause reactions in allergic individuals (eg. Soy, shellfish).  Better labels tell you which allergens are absent, as well as those which may be present.
  3. Expiration date & lot Number: shelf life varies fro different supplements, but most will diminish in potency and quality over time.  Better labels provide a USE BYE or EXPIRATION date.  They also note a LOT NUMBER for identifying product origin (for tracking any product related problems).

 

2.Directions, Dose & Value

 

Poor Label

 

Good Label

 

DIRECTIONS: Take 6 tablents daily, two with each meal.

 

Directions: Though not required on labels, directions tell how and when to take supplements.  This is important because timing your doses can affect absorption. In general:

 

·        Vitamins are best absorbed when taken with food, and in divided doses throughout the day.

·        Fat-soluble vitamins (A,D,E,K) require dietary fat for absorption, so are best taken with meals.

·        Many minerals can be absorbed effectively at any time.

·        Most herbs, probiotics, amino acids & proteolytic enzymes (not digestive enzymes, which should be taken with meals) are best taken on an empty stomach.

 

Poor Label

Good Label

Supplement facts

    1. serving size 3 tablets
    2. servings per container 20
    3. % DV (Daily Value)

Supplement facts

1. Serving Size 2 Tablets

2. Servings per container 30

3. % DV (Daily Value)

 

1. Serving size: SERVING SIZE is required on labels. It recommends the number of tablets, capsules, spoonfuls, ect. Taken at one time.  Be ware that a serving is not necessarily the total recommended daily amount.

 

2.      Cost-Effectiveness: To determine, first find the SERVING SIZE.  Then read the directions to see how much servings are suggested daily.  Finally, divide the number of servings needed into the number of SERVINGS PER CONTAINER.

 

Example: Assuming the two bottles above have the same ingredients and cost. The product on right offers more servings, and is a better buy. Product on left just has less nutritive ingredients, or more filler, in each pill.

 

3.      % DV (Daily Value): The daily value of a nutrient represents the amount expected to meet the daily needs of an “average” healthy person.  On labels, % DV indicates provided by one serving.  DVs have not been established for herbs, essential fatty acids and other nutrients.

 

Note: Many experts in nutrition think that suggested DV levels for some nutrients are far too low to optimize health.  This is why certain ingredients may be present at greater than 100% DV levels.

 

3.Games Labels Play

 

There is no free lunch in the world of supplements.  A bottle that costs less probably contains less – either fewer nutrients, or less effective forms of nutrients.  Educate yourself; compare ingredient amounts, forms and sources, and watch out for labeling tricks such as these.

 

“Padding” the label

 

padding” the label is a common way for supplement marketers to make their ingredients list look more complete and beneficial than it really is.  Padding methods include:

 

Poor Label  amount per serv.

Good Label  amount per serv.

1.CoQ10……….1000mcg

2.Oat Bran………20mg

   Oat fiber……….1mg

3. Oat flavonoids…25mcg

1. CoQ10………….50mg

 

  1. Pixie Dust:  Adding useful ingredients in therapeutically useless amounts. Some brands use tiny amounts of nutrients just to get the ingredient on the label.  Learn how much nutrient is required, and be watchful of inappropriate measurement sizes. (See Weights & Measures below.)

 

Example: CoQ10 useful range is 30mg to 400mg (milligrams.)  product on left provides 1000mcg  (microgram) of CoQ10, the equivalent of just one mg!  product on right provides a beneficial 50mg.

 

  1. Sounds Good:  Adding impressive but irrelevant ingredients, often in useless amounts, that are of no benefit to the formula.

Example: Whole grains such as oats are part of a heart healthy diet, but the product on left provides less than a pinch 20mg of oat bran.  Product on right includes no irrelevant ingredients in useless amounts.

 

  1. Expanding Assets:  Separately listing the parts of a single ingredient to give the illusion of additional ingredients. 

Example: Fiber and flavonoids are part of oats, not more ingredients.

 

The “Name’s the Same” Game

 

A common trick is to provide unproven, weak or useless forms of familiar, good ingredients.  Buyer beware!

 

Poor Label  .

Good Label   .

Pygeum Bark Powder

Pygeum Africanum…..100mg

Pygeum Bark Extract

Pygeum Africanum (Standardized to 13% total sterols……….100mg

 

Example: Studies suggest that Pygeum bark standardized extract helps support prostate health.  Product on left uses unresearched powdered bark.

 

 

Proprietary Blend = “It’s a Secret”

 

Some companies may hide the quantity and quality of their ingredients by calling their formula  a “Proprietary Blend.”  This term may allow manufacturers to use a lot of nutrient from a cheap source and very little from a good source without disclosing how much of each you are actually getting. 

 

This deceptive practice is legal—as long as the secret blend:

·        Is labeled “Proprietary Blend” (or fanciful trademark name)

·        Lists individual nutrients in descending order by weight

·        Lists the total weight per serving

 

When you see the word “Proprietary,” ask: “how relevant is the first or second ingredient?”  Sometimes, the most abundant ingredients are either fillers, or inexpensive, less effective forms.

 

Poor Label              amount per serv.

 

Good Label             amount per serv.

Special Proprietary Women’s Blend

Alfalfa herb, Black Cohosh root, Chaste Tree berry, Dong Quai root, Licorice root………….350mg

Black Cohosh root

Cimicifuga Racemonsa (2.5% total triterpene glycosides)…….125mg

Chast Tree berry

Vitex agnus-castus (0.5% agnusides)………………..100mg

Dong Quai root

Angelica sinensis (5:1 extract)..75mg

Licorice root

Glycyrrhiza glabra……………50mg

Example: Legally, product on left could contain 99% alfalfa filler and only 1% of all the other herbs together! The Good Label tells all.

 

Hiding Outside the Box

 

Another clever way to hide the quality of ingredients is by listing them outside the Supplement Facts box, in the Other Ingredients section located beneath the box.  This section is usually intended for listing agents used in the tableting or encapsulation process.

 

 

Poor Label

 

Good Label

Other Ingredients: Cellulose, stearic acid, spirulina, lycopene, grape seeds.

Other Ingredients: Cellulose, vegetable magnesium stearate.

Example: Agents used in supplement manufacture (i.e. cellulose and stearates) should be listed under Other Ingredients.  Product on left also uses this section to list catchy sounding spirulina, lycopene, and grape seeds.  With no amounts listed, assume these ingredients are present in low levels that provide little value.  A supplement maker who is proud of a product’s nutritive ingredients will fully disclose amounts within the Supplement Facts box not list these ingredients along with manufacturing agents in the Other Ingredient section.

 

4.Understanding Herbs

 

 

Herb Forms: Powders, Tinctures, Extracts

 

The form, preparation and concentration of an herb affects its potency and influences the herb’s potential for therapeutic effectiveness.  the potency of all herb forms except standardized extracts are uncertain and depends on factors invisible to the consumer (i.e. soil quality, rainfall, seasonal climate, harvesting methods, storage methods and age).

 

            Know Your Plant Parts: Medicinal plants often have specific parts that are most effective therapeutically, such as the root for goldenseal, the leaf for raspberry, and the blossom for clover.  Products using irrelevant plant parts may cost less, but offer little or no benefit!

 

Powdered Herb

 

Often encapsulated or used as tea, powdered herbs are more likely than other forms to lose potency when exposed to air.  Fresh, high quality powdered herb may add therapeutic or nutritional value to a supplement.  Low quality powders may provide little benefit.  Look for expiration or “use by” dates.

 

Poor Label

 

Good Label

Saw Palmetto………..320mg

Saw Palmetto berry

Serenoa repens……320mg

Example: If the label doesn’t say otherwise, assume the form of herb is powdered.  Better labels specify plant part and latin name (genus and species).  Sometimes a less effective species of a plant is used to save money.  Check to see if other related species may be equally effective.

 

Tinctures and Fluid Extracts

 

Tinctures contain the soluble parts of dried or fresh herbs, often extracted in a mixture of alcohol and water, vinegar or glycerin.  Tinctures are usually dispensed by drops. This form is more stable and thus has longer shelf life than powdered herb.

 

Poor Label

 

Good Label

Saw Palmetto berry

Tincture…………..320mg

Saw Palmetto berry

Serenoa repens 1:5 tincture, 40% alcohol………………..320mg

Example: Better labels specify tincture strength as a ratio.  Regular tinctures are made using 1 or 2 parts herb to 10 parts solvent, yielding strength ratio of 1:10 or 1:5.  higher potency tinctures (also known as fluid extracts) use more herb in less solvent, yielding stronger 1:3, 1:2, or even high strength 1:1 ratios.

 

Concentrated and standardized extracts

 

Concentrated or standardized extracts (solid, powdered, liquid) are generally prepared from evaporated herbal tinctures or teas.

 

Poor Label

 

Good Label

  1. Saw Palmetto Berry Extract..……..320mg
  2. Saw Palmetto berry standardized extract………..320mg
  1. Saw Palmetto berry

Serenoa repens extract 5:1…………320mg

  1. Saw Palmetto berry

Serenoa repens (standardized to 85%-95% fatty acids and sterals)………320mg

 

  1. Concentrated extracts commonly use 4 to 8 parts of plant matter to make 1 part extract (4:1 to 8:1).  Some may use up to 200 pounds of herb to make 1 pound of finished product (200:1)!

Example: A better label tells you the concentration strength by noting the ratio of herb to extract.  This is often appears after the plant name.

 

  1. Standardized Extracts are lab-analyzed to provide a verified amount of one or more nutritive ingredients.  In many cases, proportional amounts of other constituents are also present, retaining the natural “fingerprint” of the whole herb.  Standardized extracts are the most consistent, and often the most potent, form of an herb.  They are used in the majority of studies demonstrating therapeutic effectiveness.

Example: Standardized extracts provide a set percentage of an herb’s researched nutritive ingredient.  Useless this percentage is noted on the label, the term “Standardized” is meaningless.

 

5.Beware of False Claims

 

Is it science of is it marketing?  To avoid being misled, question all claims on supplement labels as well as in advertisements.  Although government Guidelines restrict the types of claims that manufacturers can legally use to promote their products, not all companies comply.  Many promises mount to little more than marketing hype.

 

Use common sense to decide if a claim seems realistic.  Be aware of emotionally charged, misleading language in advertising.

 

When doubt, contact the company and request information to support a claim.  Unbiased research and human studies are most relevant.  If the science seems legitimate, verify that the form and dose used in product match form and dose showing benefit in studies.

 

Weights & Measures

1 kilogram (kg) = 1000grams (g)

1 gram (gm) = 1000 milligrams (mg)

1 milligram (mg) = 1000 micrograms (mcg)

1 liter = 1000 milliliters (ml)

946 milliliters (ml) = 1 quart

30 ml = 1 fluid once

1 teaspoon, medical = 5 milliliters (ml)

1 tablespoon = 15ml = ½ fluid ounce

28.35 grams (gm) = 1ounce

1 kilogram = 2.2 pounds

Vitamin E

Measured in mg alpha-tocopherol equivalents 1 mg alpha tocopherol = 1.49 IU

Beta Carotene 1mg = 1667 IU

Vitamin A

1 RE (retinol equivalent) = 5 IU

1 RE = 6mcg of beta carotene

1 RE = 1mcg of retinol

Vitamin D

Measured in mcg cholecalciferol

1 mcg cholecalciferol = 40 IU

 

 

 



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Ergopharm Dietary Supplements
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Date: July 29, 2006 03:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ergopharm Dietary Supplements

About Ergopharm Supplement company.

"Welcome to Ergopharm, a division of Proviant Technologies, the leader in innovative sports supplement technology. Led by world famous chemist Patrick Arnold, Ergopharm employs a full team of chemists, food scientists, and microbiologists to bring you the most effective and highest quality products in the sports supplement marketplace.

Ergopharm started as the industry leader in prohormone products, but has since expanded its line to offer a full spectrum of cutting edge dietary supplements - including fat loss products, protein powders, cellular energizers, and mood enhancers.

As always, Ergopharm stays committed to stringent quality control and its facilities follow strict GMP Guidelines. Ergopharm has in-house chemical, physical, and microbiological analytical instrumentation and staff to ensure its products live up to every specification necessary.

If you are not buying Ergopharm products, then you are missing out on the future of sports nutrition."

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Lutein to fight age-related macular degeneration!
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Date: February 27, 2006 05:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lutein to fight age-related macular degeneration!

Lutein: The Antiordinary Antioxidant

Lutein belongs to a class of compounds known as carotenoids. Carotenoids in general are yellow, orange, or red pigments responsible for many of the colors of the foods we consume each day. To date, over 600 carotenoids have been identified in nature, but are only produced by plants, algae and bacteria leaving humans and animals to consume carotenoids in the diet. Forty to fifty carotenoids are consumed in the typical US diet, but only 14 have been detected in the blood, indicating a selective use of specific carotenoids by the body. Lutein is one of these carotenoids found in the blood and has been increasingly associated with eye health over the last decade.

Lutein’s role in eye health

In the human eye, lutein is concentrated in the center of the retina in an area known as the macula. Lutein is deposited in the macula through the lutein we consume in out diet or through supplements. This area is responsible for human central vision and is colored intensely yellow due to high concentrations of lutein. Lutein is thought to be beneficial for eye health by reducing damage in the eye in two ways: 1) by absorbing blue light (blue light is thought to increase free radical formation in the eye) and 2) by acting as an antioxidant, reducing damage in the eye caused by free radicals. Leading carotenoid researchers believe these functions may lead to a reduced risk of age-related macular degeneration (AMD) and cataracts.

Age-related macular degeneration

Macular degeneration is the leading cause of blindness in the USA in those over 65. twenty-five and thirty million people are afflicted worldwide and currently there are no effective treatments for the disease. The disease has two forms known as dry and wet AMD.

Ninety percent of AMD cases diagnosed are the dry form. In dry AMD, also referred to as early AMD, debris deposits under the center of the retina (known as the macula) interfering with its normal function. Parts of the macula atrophy, causing the central vision to slowly become dimmer or more blurry. Wet age-related macular degeneration, also known as late AMD, often develops in areas where dry AMD exists. Abnormal blood vessels grow and leak blood and fluid under the macula, causing scarring, which leads to rapid loss of central vision.

Dr. Joanna Seddon published one of the first studies demonstrating a link between lutein intake and AMD risk in 1994 (1). This epidemiological study compared the risk of developing AMD to nutrient intake and showed a significant reduction in risk for developing AMD as lutein intake reached 6mg per day (57% reduction in risk). Since the Seddon study, researchers have shown that increasing dietary lutein intake raises blood levels of lutein as well as levels of lutein in the eye (2). Bone et al. demonstrated that eyes with higher levels of lutein were less likely to be afflicted with AMD (3).

The latest clinical trial that investigated lutein’s role in AMD is known as the lutein antioxidant supplementation trial (L.A.S.T) (4). This study evaluated the effects of lutein supplementation for one year in 90 veterans diagnosed with dry AMD. Supplementation with lutein in these subjects significantly increased the concentration of lutein in the macula. Improvements in visual function were also detected with lutein supplementation. Glare recovery, visual acuity, and contrast sensitivity were all improved. This study continues to build on clinical evidence that the dry form of AMD may be responsive to changes in nutrition.

Cataracts

A cataract is a natural clouding of the lens, the area of the eye responsible for focusing light and producing clear, sharp images. For most people, cataracts are a natural result of aging. Currently in the US, cataracts are the second leading cause of blindness in the elderly behind AMD.

Lutein is the major carotenoid that has been identified in the human lens asn is thought to provide similar benefits to the leans that are seen in the retina. Two large epidemiological studies consisting of >70,000 women (age 45-71) and >30,000 men (age 45-75) compared the risk of cataract extraction to nutrient intake (5,6). Similar to AMD, a significant reduction in risk of cataract extraction was associated with lutein intakes of 6mg per day (20% reduction in risk). Besides cataract extraction, higher levels of lutein consumption have been associated with a decreased risk of cataract development and improvements in visual acuity and glare sensitivity in people with age-related cataracts.

Lutein consumption

The richest source of free lutein in the typical US diet are dark green leafy vegetables, with the highest concentration found in kale followed by spinach.

The average daily lutein intake is low, average between 1-2 mg/day. Currently there is no recommendations of the dietary Guidelines for Americans 2005 (9 servings of fruits and vegetables every day) you would consume between 4 and 8 mg of lutein a day (7). Epidemiological evidence, animal models, and clinical data have indicated levels of 6-10 mg a day may be necessary to realize the health benefits associated with lutein consumption. By continuing to increase our intake of lutein, we begin to ensure the optimal health of our eyes.

References:

Seddon et al. (1994) dietary carotenoids, vitamin a, c, and e, and advanced age-related macular degeneration. Eye disease case-control study group. JAMA. 272: 1413-20.

Bone et al. (2000) Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Exp. Eye Res. 71: 239-45.

Bone et al. (2001) Macular pigment in donor eyes with and without AMD: a case-control study. Invest. Ophthalmal. Vis Sci. 42: 235-40.

Richer et al. (2004) Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-relaged macular degeneration: the veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 75: 216-30.

Brown et al. (1999) A prospective study of carotenoid intake and risk of cataract extraction in the US men. Am. J. Clin. Nutr. 70: 517-24.

Chasen-Taber et al. (1999) A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am. J. Clin. Nutr. 70: 509-16

HHS/USDA. Dietary Guidelines for Americans 2005. //www.healthierus.Gov/dietaryGuidelines/CDC. National health and nutrition examination survey data 2001-2002. //www.cdc.gov/nchs/about/major/nhanes/nhanes01-02.html

Brandon lewis, Ph.D. is the applied research and Technical services manager at kemin health, L.C. in des moines, iowa. His responsibilities include the initiation and management of laboratory projects pertaining to the inclusion and analysis of kemin ingredients in vitamins and dietary supplements, as well as developing new applications and prototypes that include kemin ingredients. Prior to joining kemin, Brandon was enrolled at the university of Florida where he received his Ph.D. in Nutritional Science from the department of Food Science and Human Nutrition.



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Devine Skin - New to VitaNet to help all your Hair and Skin needs.
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Date: February 25, 2006 01:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Devine Skin - New to VitaNet to help all your Hair and Skin needs.

Divine Skin

DS Laboratories was launched in 1996 with the single-minded goal of developing state-of-the-art solutions for skin care and hair removal industries. Today, DS Laboratories is a performance-oriented company backed by serious research and development. New product introductions are driven only by genuine advances in technology and performance. The company has grown steadily over the last few years with a network of top specialty retailers across North America and distributors throughout Europe, Asia, and South America. The company occupies corporate headquarters in Lake Success, New York and a 55,000 square-foot cutting-edge production facility. This facility is fully certified and strictly adheres to GMP Guidelines.

A single use of DS Laboratories products immediately confirms that these products have been developed for performance with clinical efficacy. We pride ourselves on manufacturing only those products that provide genuine results for the customer. DS Laboratories products are now recommended by health care professionals, beauticians, and leading spas around the country.

All of DS Laboratories products feature a remarkably innovative liposome technology that was the result of years of research and the involvement of some of the most brilliant minds in biochemistry. This technology dramatically enhances the effectiveness of the active ingredients in the products. Incredible strides have been made in the treatment of cellulite, hair loss, acne, and other common ailments.

We are committed to the highest standards of ethics and integrity; we are responsible to our customers, to our employees, and to the environment we inhabit. We do not take professional or ethical shortcuts. While we expect profits, it is only from the work that satisfies and benefits our customers.

Our mission is to continue developing a steady stream of innovative new products and aesthetic treatments to improve appearance and well-being, and in turn, satisfying customer needs and improving the quality of life.



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Now Foods -QUALITY- High Standards and Attention to Detail
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Date: December 27, 2005 09:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Now Foods -QUALITY- High Standards and Attention to Detail

QUALITY “High Standards and Attention to Detail”

  • Family Owned and Operated since 1968
  • In-House Microbiology Lab
  • Member-NNFA and AHPA
  • “A” Certified GMP Manufacturer
  • 203,000 Square Foot Manufacturing Packaging Facility

As you shop for dietary supplements you’re faced with an almost dizzying array of choices. Naturally, every product claims to be this, that and the other. But you’ve heard the stories in the media of products that don’t live up to their claims. So how do you know who’s telling the truth? Perhaps a better gauge of a product’s quality is the manufacturer and their history. Do they have a legacy of producing quality goods? How long have they been in business? Is their track record good or do they have a history of product recalls and bad press? If you’re responsible for your family’s health and well-being, it pays to do your homework when it comes to the products you purchase for them. NOW® Foods has been manufacturing dietary supplements and whole foods for 35 years.

Companies that thrive and continue to grow for this long don’t do so because they produce poor quality products. They do so by maintaining extremely high standards and paying special attention to every detail, which is the secret to product quality. At NOW® Foods, these high standards and attention to detail are evident in every aspect of our operations, from receiving to production to finished goods, just as they have been for 35 years. You’re committed to buying only the best for your family, and we’re committed to supplying only the best for our customers.

Quality products are made using the highest quality ingredients. NOW Foods purchases raw materials from only the most reputable vendors, who are required to provide detailed specification sheets and lot-specific certificates of analysis for every shipment we receive. These documents provide information on the quality of the raw material and the various analyses used to verify that quality. Shipments that do not meet our quality standards are sent back to the manufacturer with a point by point report card of why the shipment was refused. We simply don’t just accept every shipment that’s delivered to our dock – no ingredient gets a free pass into our production facility. In addition, we also perform random vendor audits throughout each year to ensure that they’re meeting our stringent quality standards. NOW ® Foods is always vigilant when it comes to quality, just as you are. Another way we maintain high quality standards is by choosing to buy and incorporate registered and/or trademarked ingredients into our products. Each of these ingredients are exclusively produced by a company that owns proprietary manufacturing rights and licenses selected companies like NOW® to use these top quality ingredients in their products.

These registered/trademarked ingredients must undergo even more rigorous analysis and controls than other ingredients, and so offer additional assurance that products containing them are properly manufactured and labeled. Additionally, to maintain the integrity of their ingredient’s reputation, the trademark owner will independently test finished products from manufacturers to verify the quality meets their standards and the label claim of the company licensed to use it. You may be familiar with some of the trademarked ingredient NOW® uses such as, Ester-C® vitamin C, Chromemate® Chromium and L-Carnipure® Carnitine.

Scientific analysis of ingredients is extremely important to ensure the integrity of any dietary supplement. NOW Foods has made substantial investments in the development, construction and staffing of numerous inhouse laboratories, including an advanced instrumental analysis laboratory, a “wet lab” and a state-of-the-art microbiology lab. This saves us the time and expense of having to send samples out to commercial labs for analysis. While we use independent labs to verify our in-house test results, our capabilities allow us greater control over product quality and quicker approval of raw material shipments for production, which means fresher products for consumers. Our investment ensures that NOW® will be able to meet ever-increasing demands for accurate product analysis and outstanding product quality. NOW® is unique in the industry in that we annually spend more on Quality Assurance & Control than we do on Marketing and Advertising combined. What good is a lab without qualified people? NOW® employs an expert team of highly qualified scientists and technicians, including four Ph.D.’s. They’re constantly working to develop new and improved analytical methods, and their efforts contribute not only to our product quality but that of the entire industry as well.

This is all great, you say, but what about your facility and the equipment you use to manufacture products? Our 203,000 square foot facility is designed and built to standards that exceed food-packaging Guidelines. It supports pharmaceutical-grade operations, which greatly enhances our ability to produce the highest quality products quickly. All this means fresher, more effective products on store shelves for consumers. NOW® Foods is an ‘A’ rated GMP-certified manufacturer, one of the first companies in the industry to attain GMP (Good Manufacturing Practices) certification. We’re also certified by QAI (Quality Assurance International) as an organic manufacturer. As consumers become increasingly demanding of supplement quality and safety, NOW® is ready to meet this demand with sound science and state-of-the-art research, manufacturing, and packaging capabilities. We are certain that our efforts to consistently maintain the highest product quality will help make your natural product purchasing decisions easier.



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Vitaberry Plus + Super Fruit Antioxidant
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Date: December 07, 2005 05:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitaberry Plus + Super Fruit Antioxidant

Vitaberry Plus +™ Super Fruit Antioxidant

By Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT Guidelines The new federal Guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),
- Catalase (neutralizes peroxides),
- Functions similar to reduced Glutathione (GSH),
- Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent),
- Functions similar to Glutathione S-transferase (GST),
- Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS Guidelines report at: etaryGuidelines/dga2005/document/

ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697

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Source Naturals - Continuous Quality Assurance
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Date: August 20, 2005 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals - Continuous Quality Assurance

“I oversee all the inspections, tests, and document reviews performed by our dedicated Quality Control staff to ensure that nothing compromises the healthfulness and high quality of our products.” Norm Nelson, Ph.D., Quality Control Director

Continuous Quality Assurance

Our Quality Control Department includes staff trained in microbiological assays, heavy metal screening, analytical chemistry and Eastern and Western herbalism. They utilize procedures that go beyond minimum industry requirements to ensure product excellence. All raw materials and finished goods must meet our inspectors’ rigorous quality specifications at every stage of manufacturing.

Pure Raw Materials

Bulk raw materials must be accompanied by Certificates of Analysis provided by the vendors. They are sampled and inspected according to a long list of specifications, including appearance, color, odor, flavor, texture, absence of extraneous material, and potency of active constituents. Vitamins, minerals and amino acids are screened and/or tested for impurities, while materials, such as herbs, that are biological in origin are tested for microbiological contamination.

Bioavailable Manufactured Product Inspectors scrutinize finished tablets to see that they meet our standards for consistency in size, color, aroma or taste, are not broken, and contain no contaminants. Representative samples are taken to verify potency. Tablets and capsules are tested to ensure they are consistent in size and comply with USP standards for weight variation. Threshold utilizes USP disintegration standards* as its Guidelines to ensure tablets will break up appropriately after ingestion, making the ingredients available for use by your body.

*Under USP 25 standard conditions: Coated tablets: 50 minutes in water. Capsules: 45 minutes in buffered acetate or water.

Rigorous Laboratory Procedures

Methods used include: HPLC (High Performance Liquid Chromatography), IR (Fourier Transform Infrared), UV/Vis Spectrophotometry, Graphite Furnace Atomic Absorbance Spectroscopy, TLC (Thin Layer Chromatography), Microbiology testing, and organoleptic inspection including visual, color, odor, clarity, pH, and taste.

Raw materials must comply with vendor Certificates of Analysis as well as with our rigorous specifications.

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Common Sense Guidelines for Avoiding the Flu and Colds
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Date: July 28, 2005 02:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Common Sense Guidelines for Avoiding the Flu and Colds

Common Sense Guidelines for Avoiding the Flu and Colds

1. Eat a healthy diet. The most important way to prevent being infected is through a proper diet. Raw vegetables, fruits, sprouts, nuts, and seeds should be eaten in abundance. Fresh fruit juices such as apple and grape can help the body flush out toxins. Do not overeat. Avoid sugar, soft drinks, white flour products, chocolate, fried foods, alcohol and tobacco.

2. Exercise for health. Exercise at least three times per week to help strengthen the immune system. Regular exercise is known to help enhance the body’s resistance to disease. Exercise can improve the white blood cell count in the body, which fights germs. It stimulates the lymphatic flow and blood circulation, which allows for the blood flow to increase to the brain and all areas of the body. It can help release hormones that actually help you to feel good. Exercise can help relieve anxiety and stress in the body. It can help increase energy and an overall sense of well being.

3. Get plenty of rest. A good night’s sleep helps the immune system fight off illness. This keeps your immune cells powered up, according to research done at the San Diego Veterans Affairs Medical Center. In the study, 42 healthy volunteers were allowed only four hours of shut-eye overnight, which resulted in 30 percent drop in natural killer cells (key players in the battle against viral infections). Sleep deprivation also decreased immune cells, such as T-lymphocytes.3

4. Wash hands regularly. Viruses are easily transmitted during casual contact like shaking hands or touching a doorknob. Wash hands after coming into contact with someone who is ill. Keep hands away from face and mouth.

5. Use paper cups in the bathroom. Viruses can often spread through the family. Using small, disposable paper cups in the bathroom may stop some of the transmission. Toothbrushes should also be replaced regularly to avoid recontamination.

6. Wash towels and linens often. If someone in the family becomes ill, wash towels daily. Hot water should be used in washing to kill the viruses involved.



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Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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In men under 65, prostate surgery can save lives.
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Date: July 27, 2005 03:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: In men under 65, prostate surgery can save lives.

10. In men under 65, prostate surgery can save lives.

When it comes to treating prostate cancer, one question prevails: To have surgery or not to have surgery? Since many cancers are slow growing, doctors often suggest that patients take a wait-and-see approach, opting to monitor tumor growth instead. While this gamble can pay off, those with faster-growing cancers may not be so fortunate. A new study, published in the New England Journal of Medicine, determined that when men under age 65 opt for surgery, the odds of surviving prostate cancer increase while chances of the cancer recurring decrease.

At a glance, the findings may seem to contradict research that urges men to watch and wait, but the study targeted patients with localized tumors large enough to be felt during a manual rectal exam. Following radical prostatectomy, when surgeons remove the prostate, surrounding tissue and lymph nodes, cancer was less likely to spread locally or to distant sites. After 10 years, 19.2% of the men in the surgery group had local progression, compared to 44.3% in the watchful waiting group. Among the surgery group, 15.2% experienced distant cancer progression, while 25.4% of those who eschewed surgery had their cancer spread.

Now that you know the ins and outs of this complex but treatable disease, there’s really no good excuse to avoid getting regular screenings and following prevention Guidelines. Being proactive about your prostate could save your life.



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Vitanet ®

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The Role of Naturally Occurring Progesterone in the Body
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Date: July 25, 2005 09:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Role of Naturally Occurring Progesterone in the Body

The Role of Naturally Occurring Progesterone in the Body

In light of the previous section, it is vital to keep in mind that when progesterone is produced and maintained, most of the negative side effects of estrogen are neutralized. Unfortunately, in far too many women, progesterone levels fail to do the job. Let’s discuss exactly what progesterone is responsible for.

A woman’s ovaries produce two key hormones: estrogen and progesterone during her ovulatory years. The corpus luteum makes progesterone just before ovulation which rapidly escalates during the two week period following ovulation. The primary task of progesterone is to support implantation and sustain pregnancy. It does this by inhibiting uterine contraction and by suppressing the immune system’s response to the developing embryo as a foreign body.2

During the last two weeks of a woman’s menstrual cycle, progesterone is considered the dominant female hormone. During pregnancy, the placenta takes over the task of progesterone synthesis. Progesterone is also made in limited amounts in the adrenal glands of both men and women and in the testes of the male.

PROGESTERONE SECRETION RATES

The following breakdown gives general Guidelines of amounts and time of progesterone secretion:

  • • just before ovulation............................2 to 3 mg per day
  • • just after ovulation.............................20 to 25 mg per day
  • • one week post ovulation.........................30 mg per day
  • • during the 3rd trimester of pregnancy....300-400 mg per day Women who feel physically exhilarated and sometimes experience an unusual remission of diseases like bronchial asthma during pregnancy may be responding to elevated progesterone levels which help to boost the production of natural cortisone.

    Approximately twelve days following ovulation, if fertilization has not occurred, progesterone levels decline rapidly, which initiates the shedding of the uterine lining, also known as menstruation.

    In time, progesterone is transported through the bloodstream to the liver where it is metabolized and excreted as waste through the kidneys (urine) and the bile. Typically, pregnancy tests are reacting to increased levels of HCG or of progesterone in the urine, indicating that pregnancy has occurred. (Note: What is crucial to remember is that a woman’s cycle, regardless of her age, may not be characterized by the above scale. A number of factors may cause estrogen to remain dominant, even after progesterone is supposed to take over in the latter half of the cycle. Even young women who suffer from nutritional deficiencies, stress, etc. may experience an estrogen dominance, suggesting the need for natural progesterone supplementation.)

    THE THREE-FOLD ACTION OF PROGESTERONE

    1. It ensures the implantation and development of a fertilized egg and subsequent embryo and fetus.

    2. It acts as a precursor to other steroid hormones such as cortisone which is produced in the adrenal glands and contributes to the production of the sex hormones including testosterone.

    3. It exerts a number of desirable physiological actions.

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    Pain - Post Op and Relaxation
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    Date: July 13, 2005 09:24 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Pain - Post Op and Relaxation

    Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR.

    "Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music.

    Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good.

    "These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization.

    Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz.

    On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed.

    Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery."

    Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill.

    -----------------------------

    Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association.

    The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998.

    A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study.

    There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity.

    Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density.

    The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group.

    These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70.

    "We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research.

    "Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus.

    As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D.

    Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine.

    -----------------------------

    Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds.

    "The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander.

    "When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the airway and can bring breathing to a halt."

    Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain.

    These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comparison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood.

    "This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added.

    ------------------------------

    Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher.

    Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development.

    These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study.

    "We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University.

    Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery.

    The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page.

    "Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk."

    The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.

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    REFERENCES
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    Date: June 25, 2005 08:13 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: REFERENCES

    REFERENCES

    1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.

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    Toxicity and Safety
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    Date: June 25, 2005 01:09 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Toxicity and Safety

    Toxicity and Safety

    Side effects and toxicity related to ginseng use are rare. The FDA categorizes ginseng for use as a tea as “generally recognized as safe.” Some reports of toxicity have not been re c o g n i zed by reputable herbalists because of poor observations and data.4 3Many of the re p o rted tox i c effects do not even cite the particular species of ginseng. Most reputable studies re p o rt low risk and an absence of side effects even after prolonged or exc e s s i ve use.4 4 It is always important to buy ginseng and other natural health care products from reputable companies who test their products for purity. Quality control measures are a high priority with many companies. The ginseng market has been full of abusers who may mix cornstarch or other ingredients with the ginseng and sell it as a pure product at the full price. Some ginseng products have been sold which do not contain any ginseng. Reputable companies follow strict Guidelines to avoid such problems.

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    PADMA BASIC: A Tibetan Herbal Formula
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    Date: June 21, 2005 05:27 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: PADMA BASIC: A Tibetan Herbal Formula

    PADMA BASIC: A Tibetan Herbal Formula

    By Isaac Eliaz, M.D.

    "As an integrated system of health care, Tibetan medicine can offer allopathic medicine a different perspective on health. However, like other scientific systems, it must be understood in its own terms, as well as in the context of objective investigation. In practice it can also offer Western people another approach to achieving happiness through health and balance." --His Holiness the Dalai Lama, May 16, 1997

    In this article I want to discuss a Tibetan-based herbal formula that reflects the philosophy outlined by H.H. the Dalai Lama. PADMA BASIC® is an extensively researched formulation that bridges the gap between Classical Tibetan Medicine and the modern Western medical paradigm. With over 50 published scientific papers spanning the last 30 years, PADMA's popularity among Western medical professionals can be attributed to its history of safe use and its health-enhancing properties. The original formula, used for centuries as a cardiovascular tonic and to counteract "heat" (inflammatory processes or infections), made its way to Europe by the first half of the 20th century. Acceptance of an ancient Tibetan formula into the Western medical tradition requires sensitivity to both the original Tibetan intention, and the rigorous requirements of the international pharmaceutical community. Today PADMA BASIC is produced in accordance with strict manufacturing Guidelines. The herbs are grown organically, or meticulously tested to ensure they are not contaminated. Ingredients are verified using thin layer or high pressure liquid chromatography. While the highest "scientific Western methods" are used, traditional Tibetan "scientific methods" of smelling and tasting are also followed.

    PADMA BASIC can be understood from two viewpoints. In Classical Tibetan Medicine, good health means maintaining a dynamic equilibrium of universal elemental forces. Illness is a manifestation of imbalance. Therapeutic intervention aims at restoring balance by treating the cause, not just the symptoms. Within this traditional model, PADMA has three functions:

  • * Padma is a cooling formula.
  • * Padma enhances the movement of wind.
  • * Padma vitalizes blood (a result of moving wind). To the Western medical practitioner, untrained in Classical Tibetan Medicine, these concepts provide little practical guidance. However, we can examine such energetic terms in relation to "Western Physiology."
  • * Cooling effect: Our body systems reflect our Western lifestyle, which tends to "excess heat" caused by running too fast without a break; eating on the run, not sleeping enough, etc. The result is inflammation, the hallmark of imbalances involving our cardiovascular and immune systems, cell health, and much more. Since inflammation causes oxidative stress, such a formula has profound antioxidant value.
  • * Enhancing wind: This concept relates to flow in the body. When substances heat up they get sticky and do not move harmoniously. In Western medicine this translates to issues such as hyperviscosity or blood thickness, and circulatory imbalances.

  • * Vitalizing blood: As the system cools and flows harmoniously, circulation improves, influencing multiple systems from memory to cardiovascular health to immunity. Following the Western medical paradigm, extensive clinical research demonstrates that PADMA supports circulation, cardiovascular health and immunity, moderates inflammation, and has antioxidant effects. From a pharmaceutical point of view, its compounds can be classified into functional groups, including tannins (anti-inflammatory, antioxidant, cleansing), polyphenols/flavonoids (immune and circulatory support, anti-inflammatory, antioxidative), and essential oils (digestive support, cleansing, anti-inflammatory, immuno-stimulating). Research shows that the circulatory and cardiovascular benefits of PADMA BASIC are partly due to its antioxidants. These compounds promote arterial health and normal blood flow, which, in turn, supports oxygen supply to the heart, extremities, and all living systems. They also protect blood lipids from oxidation, shown in controlled studies to contribute to detrimental vascular effects. While specific nutrients are beneficial, the synergy created by combining ingredients far exceeds their individual effects. It is the unique integration quoted by H.H. the Dalai Lama that is responsible for such benefits. As we move forward to understand and research ancient formulas, it is my belief and clinical experience that we need to respect and preserve their origin and traditional indications.

    PADMA BASIC

    Ingredients: Iceland moss (Cetraria islandica), Costus root, neem fruit (Azadirachtaindica), Cardamom fruit, Red Saunders heart wood (Pterocarpus santalinus), chebulic myrobalan fruit (Terminalia chebula), Allspice fruit, bael tree fruit (Aegle marmelos), Calcium Sulfate, Columbine aerial part (Aquilegia vulgaris), English Plantain aerial part, Licorice root, Knotweed aerial part (Polygonum aviculare), Golden cinquefoil aerial part (Potentilla aurea), Clove flower, Spiked ginger lily rhizome (Hedychium spicatum), Valerian root, Lettuce leaf (Lactuca sativa), Calendula flower, Natural Camphor (Cinnammum camphora).

    Dr. Isaac Eliaz is a medical doctor and licensed acupuncturist with extensive training in complementary modalities. For 15 years, his practice has centered on the integrative treatment of cancer. He has been involved in numerous studies investigating the effects of nutritional supplements on cancer and has been granted two patents.



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    Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement
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    Date: June 21, 2005 05:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplement

    Take Your Vitamins: Reviewing Scientific Approaches to Selecting Daily Multiple Supplements

    By Adina Licht, MS

    Adina Licht, M.S. is a Nutritional Scientist and Science Writer who works as a Marketing Specialist for Source Naturals. She has a B.A. in Environmental Science from UC Berkeley, an M.S. in Nutrition and Food Science from San Jose State University, and training in Technical Communication from Cal State Hayward. Her work has appeared in publications such as Advances in Packaging and Development, Health Supplement Retailer and Delicious Living.

    Americans Need More Nutrients

    The U. S. population is drastically malnourished. According to the latest A. C. Nielsen survey, only 12% of Americans claim to eat the 5 recommended servings of fruits and vegetables each day (Warner, 2004). And approximately 1/3 of the calories that people do consume are from nutrient-poor foods such as alcohol and soda (Yang, 2004). This combination has led to a population that consumes too few nutrients, which according to an article in the Journal of the American Medical Association (Fletcher, 2002) puts people at risk for long-term health concerns. With Americans eating fewer healthy foods, taking a daily multiple is one way for people to increase their intake of nutrients. But the search for what defines a good multiple can be confusing, even to health care professionals.

    The Confusing U.S. Government Standards

    Scientists first recognized the need for vitamins in the early 1900s (Levenstein, 1993). But setting U. S. government standards for vitamins and minerals didn't start until healthy soldiers were needed to fight World War II. And when a committee of scientists was asked to determine the levels of nutrients needed to maintain good health they could only agree on "recommended allowances" to prevent deficiency with a wide margin of safety. In 1941, these allowances became the first Recommended Dietary Allowances (RDAs) for the nation (Levenstein, 1993). In 1997, the Food and Drug Administration (FDA) used latest RDAs to set the new Dietary Reference Intake (DRI) standards, which included Adequate Intakes (AIs) for when there was insufficient evidence to determine an RDA, and Upper Intake Levels (ULs) as the safe daily upper limit. To simplify the information, food labels express nutrient information as a percentage of the Daily Value (DV), which includes RDA values for a healthy adult who consumes 2000 calories per day (Whitney, 2002). However, these values do not include AIs or ULs and many individuals need different levels of nutrients than these.

    Confusing Standards equals Confusing Recommendations

    The RDAs and subsequent DRIs are the basis of the nutrient standards for at least 40 different nations and many professional health organizations. Currently, the American Dietetic Association (ADA) recommends that people who cannot reach the DRIs through diet take a multiple with nutrient levels that do not exceed the RDAs (JADA, 2001). And in 2002, the American Medical Association (AMA) published a paper that included a recommendation for all adults to take RDA levels of vitamin supplements in their Journal of the American Medical Association (Fletcher, 2002). Despite the benefits of having Guidelines, most people only hear about the RDAs and DVs, which may be too low for preventing deficiencies while the ULs and AIs, which can be much more beneficial are rarely discussed. For example, the Daily Value of Vitamin E to prevent deficiency is 30 IU while the daily Upper Intake Limit is 1,467 IU. But, according to the ADA, as many as 75% of cardiologists recommend vitamin E to their patients to promote heart health, usually at a dosage of 400 IU (ADA, 2001; Meydani, 2004; & Whitney, 1998). And the Daily Value for Vitamin C is 60 mg while the daily Upper Intake Limit is 2000 mg, but in clinical studies it took 500 mg per day to help maintain healthy blood pressure (Whitney, 1998, & Hendler, 2001).

    Alternative Recommendations

    Lyle MacWilliam is a biochemist and former health advisor to the Canadian Ministry of Health, who decided to research, analyze and publish the Comparative Guide to Nutritional Supplements. In this book, the individually published recommendations from seven nutrition experts (Phyllis Balch, CNC, Dr. Michael Colgan, Ph.D., Dr. Earl Mindell, Ph.D., Dr. Michael Murray, N.D., Dr. Richard Passwater, Ph.D., Dr. Ray Strand, M.D., and Dr. Julian Whitaker, M.D.) were combined to create an ultimate blended standard of recommended median intakes for 39 nutrients to promote health. Those nutrients include vitamins, minerals, phytonutrients, and other supplements, that span 14 different health categories and are much closer to the Upper Intake Limit government standards. The guide also includes information about recommended forms, safety, purity and quality (MacWilliam, 2003). One of the most profound differences between MacWilliam?s compiled recommendations and the DRIs is the difference in the number of supplements: 39 vs. 26 respectively. The Comparative Guide standard includes additional nutrients, including many more antioxidants, based on decades of clinical research about their benefits. For example, the fat-soluble antioxidant Coenzyme Q10 that your body manufactures less of as you age is included. So is the fat and water-soluble antioxidant alpha lipoic acid that helps recycle other antioxidants such as vitamins C and E (Hendler, 2001).

    Top Ranked Multiples for Optimal Health

    In the latter half of MacWilliam's book he uses this ultimate blended standard to rank and compare 500 manufactured multiples. Of the five top-ranked multiples, only the Source Naturals multiples, Life Force and Élan Vitàl, are widely available at natural product stores and health outlets. And the new and improved Life Force formulation now rates higher than any of the products evaluated in the current edition of this guide (MacWilliam, 2004; & Mac-William, 2003). The ingredients that can be found in today's multiple supplements can vary greatly. But multiple choices don't have to lead to confusion. Health professionals, such as Lyle MacWilliam, understand the importance of remaining curious, evaluating the available research, and conferring with other scientists to determine the nutrients that support optimal health.

    References

    American Dietetic Association. 2001. Vitamin E: Disease Prevention for your Good Health. American Dietetic Association Website. Available at: Public/Other/index_nfs1001.cfm Fletcher, R. H., & Fairfield, K. M. 2002. Vitamins for Chronic Disease Prevention in Adults. JAMA. (23)287:3116-3129. Hendler, S. S., et al. 2001. PDR for Nutritional Supplements. Thomson Healthcare: Montvale. Pages 11-12, 17-21, 60-62, 103, 416-421, 486-498. JADA (Journal of the American Dietetic Association) 2001. Vitamin and mineral supplementation. J AM Diet Assoc.101: 115 Available at: Public/NutritionInformation/92_8343.cfm Levenstein, H. 1993. Paradox of Plenty: A Social History of Eating in Modern America. Oxford University Press: New York. Pages 13-15, 64-67. MacWilliam, L, et al. 2003. Comparative Guide to Nutritional Supplements. Northern Dimensions Publishing: Vernon. Pages 62-70. MacWilliam, L. 2004. Comparative Guide Individual Assessment of New Life Force Formulation. Warner, J. 2004. Few Follow '5 a Day' Fruit and Vegetable Rule. WebMD website. Available at: ent/Article/93/102158.htm Whitney, N. W., & Rolfes, S. R. (1998). Understanding Normal and Clinical Nutrition, 5th ed. Page 358. Whitney, E. N., & Rolfes, S. R. 2002. Understanding Nutrition. 9th ed. Wadsworth Thomson Learning: Belmont. Pages A, B, Y, 13-20, 55-56, 307, 331, 335-341, 401. Yang, S. 2004. Nearly one-third of the calories in the US diet come from junk food, researcher finds.



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    Fats: The Good, the Bad, the Ugly
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    Date: June 14, 2005 11:18 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Fats: The Good, the Bad, the Ugly

    Fats: The Good, the Bad, the Ugly by Thomas Sherman Energy Times, October 15, 2004

    We need fat to absorb vitamins, to keep our brains sharp, to survive. But not all fats are our friends. Find out which ones are the heroes and the villains in your diet.

    In a lot of cases health fads don't live up to their hype. But the case for consuming more good fats-the omega-3 fatty acids found primarily in fish, flax and hemp oils-is strong and growing stronger. As a nation we eat too little of these good fats, and our health would improve greatly if we relied a little less on the bad saturated fat in burgers, skipped the ugly trans fats in fries and indulged in more salmon and other seafoods.

    Fish and the Heart

    Need proof? A wealth of research supports fish oil's desirable effects, especially on heart health. While many people believe that heart disease is primarily a problem for men, women who have passed through menopause are just as susceptible to heart problems.

    " [Our] findings suggest that all women, and most likely men, would benefit from regular fish intake," says Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts University in Boston. "A tuna fish sandwich counts, as does almost any other type of fish that is baked, broiled, grilled, or poached." But she points out that fried fish, which is often cooked in hydrogenated oils, is not helpful.

    In research on more than 200 women, performed at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts, scientists found that the arterial blockages among women who dined on fish were less (and impeded blood flow less) than in women who hardly ever ate seafood. Fish was especially helpful for women who had diabetes, a disease that makes you more prone to heart and circulation problems (American Journal of Clinical Nutrition 9/04).

    These effects are important: Heart disease is the number one cause of death for women, and older women who suffer from diabetes are particularly susceptible. The number of people with diabetes has been increasing of late, mainly due to the fact that Americans are overweight. Right now about 18 million people have diabetes and another 20 million are expected to suffer this condition in the next four decades.

    " This study shows that following the current Guidelines of eating at least two servings of any type of fish per week slows down the progression of heart disease in women with coronary artery disease (CAD), especially those who were also diabetic," says Dr. Lichtenstein, coauthor of the study. "We further found that eating one or more servings per week of fish that is rich in omega-3 fatty acids, such as tuna or other dark-fleshed fish, is equally effective."

    Dangerous disruptions in heartbeat, known as arrhythmias, may also be affected by fish oil. "[E]xperiments show that fatty acids from omega-3 fish oils are stored in the cell membranes of heart cells and can prevent sudden cardiac death or fatal arrhythmias," notes Alexander Leaf, MD, medical researcher and professor at Harvard University.

    Fat for Your Brain

    The right kind of fat is also crucial for the function of your nerves and brain tissue, which is 60% to 70% fat. Incorporating omega-3 fatty acids into those cells can help keep your brain firing on all synapses. It may lower your risk of Alzheimer's disease, an irreversible form of mental deterioration that kills 100,000 Americans a year. About a thousand people a day in the US are found to have Alzheimer's, and experts believe that over the next 40 years 14 million of us will be doomed to being enveloped by the mental fog this condition produces.

    Research indicates that our brains probably need omega-3 fats for protection against the kind of damage that causes our mental capacities to slip. Once Alzheimer's starts, deterioration accelerates because brain cells start losing these fats.

    In experiments performed at the David Geffen School of Medicine at UCLA (Neuron 9/2/04), scientists looked at how a lack of docosahexaenoic acid (DHA, one of the omega-3 fats found in fish), affected the cellular processes that lead to Alzheimer's. They found that the part of brain cells that receive signals from other brain cells, the receptors, are vulnerable to damage from chemical reactions that take place inside the cells. However, DHA offers antioxidant protection against this destruction.

    When brain cells were denied DHA, the cells' receptors suffered extra harm. But when fish oil was present, brain cells were protected. In addition, animals that received extra omega-3s were better able to learn and find their way through mazes.

    Greg Cole, PhD, senior researcher on this study and a professor of neurology at Geffen, says, "We saw that a diet rich in DHA, or docosahexaenoic acid, dramatically reduces the impact of the Alzheimer's gene [which made the animals more susceptible to Alzheimer's]. Consuming more DHA is something the average person can easily control. Anyone can buy DHA in its purified form, fish-oil capsules, high-fat fish or DHA-supplemented eggs." Fishes rich in omega-3s include salmon, halibut, mackerel, sardines and herring.

    Protecting Kids from Asthma

    A surprising benefit of omega-3s has been found in pregnant women and their newborns: Pregnant women with asthma who eat fish rich in omega-3s during their pregnancy lower their children's risk of asthma.

    Not just any fish will do. The study (American Thoracic Society International Conference 5/25/04) discovered that mothers who ate fish sticks during pregnancy doubled the asthma risk in their kids. " Fish sticks are deep-fried, and they contain omega-6 fatty acids, which encourage inflammation of the airways," says study co-author Frank Gilliland, MD, PhD, professor at the Keck School of Medicine at the University of Southern California. "Oily fish [like salmon and trout] contain omega-3 fatty acids, which appear to be anti-inflammatory, and lead to the reduced potential for developing asthma and allergies."

    The USC investigation showed that when women with asthma ate oil-bearing fish during pregnancy, the risk of asthma for their children dropped more than 70%. The more fish that mom consumed, the less likely her baby was to develop asthma. Unfortunately, the study did not find the same benefit in women without asthma.

    " A family history of asthma is a very strong risk factor for a child developing asthma," Dr. Gilliland says. "It appears that oily fish interacts with the genes involved in the predisposition to develop asthma, and somehow reduces the risk."

    Although most of us try to avoid accumulating unsightly fat around our hips, the right kind of fat plays an integral part in the functioning of our bodies and may even keep us alive. Fats don't get much better than that.



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    Nutritional Scorecard
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    Date: June 14, 2005 10:52 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Nutritional Scorecard

    Nutritional Scorecard by Sylvia Whitefeather Energy Times, June 15, 2004

    For over 50 years, the federal government has produced Recommended Daily Allowances (RDAs) as Guidelines for vitamin and mineral intake. Then, in 1993, the Reference Daily Intakes (RDIs) superseded the RDAs. By applying this new designation, the government's Guidelines are now supposed to represent the designated amounts that an average person should consume. With this in mind, and the fact that many experts think you should consume more than some of the RDIs, how does your nutritional scorecard add up? Answering a few nutritional questions can point you in the right direction.

    Perfect Protein

    Are you trying to lose weight? If you are, the latest thinking on weight loss opines that eating more protein may be the key to keeping your weight down. Two recent studies published in the Annals of Internal Medicine (5/18/04) found that people who ate a low-carbohydrate, high-protein diet lost more weight and had better cholesterol levels than dieters who ate fewer fatty foods. Both studies found that a low-carb diet can improve your triglycerides (blood fats) and boost your HDL, or good, cholesterol.

    Eating protein satisfies both tummies and taste buds. Researchers have found that the amount of protein eaten in a meal determines not only how much food you eat but also how satisfied you feel after eating (J Nutr 2004 Apr; 134(4):974S-9S). And when you feel satisfied after eating less food you improve your odds of losing weight.

    We need about 50 grams of protein a day to support the body's functions. The best sources of protein are eggs, meat, milk, protein shakes and yogurt.

    Classy Carbohydrates

    Does your energy level go up and down during the day? To get off the energy rollercoaster, cut down on carbohydrates, and make sure the carbs you do eat are complex.

    Carbohydrates have been getting some unflattering press lately. Yes, if you want to lose weight, you may want to go on a strictly low-carb diet. But for those not concerned with weight, carbohydrates are the principle source of energy for the body.

    What's more, even if you do restrict carbohydrates, you should still eat a tiny bit of them. Without some carbs in the diet your body cannot regulate protein or fat metabolism. According to Michael and Mary Eades, MD, authors of The 30-Day Low-Carb Diet Solution (Wiley), "Carbohydrates control insulin and insulin controls your metabolic health."

    So, make your carbohydrates count. Indulge in complex carbohydrates: whole grains, fruits and vegetables. In those foods, carbs are accompanied by fiber and larger amounts of vitamins and phytonutrients. Other reliable sources of complex carbohydrates are whole wheat bread, brown rice and oatmeal.

    Fabulous Fiber

    Are you concerned about your heart health? Fiber from beans, oats, legumes, nuts, rice bran, fruits and vegetables helps stabilize blood sugar and reduce cholesterol. Pectins, found in apples, pears, prunes and plums, are a particularly useful form of water-soluble fiber.

    Insoluble fiber, in cereals, wheat bran and vegetables, reduces the risk of colon-related problems. In addition to adding fiber to the diet, dried beans and soybeans have been shown to lower cholesterol, improve vascular health and kidney functioning, preserve bone mineral density and reduce menopausal discomforts (AJCN 1999 Sept; 70(3 suppl):464S-74S). Fiber also promotes good bowel health and encourages the growth of beneficial intestinal flora.

    You need 25 to 40 grams of fiber daily. If you have cut back on your carbohydrates, be sure to take a reliable fiber supplement.

    Fantastic Fats

    Do you have problems focusing on mentally challenging tasks? If so, you should eat more fish and get more of the omega-3 fatty acids that fish and flax contain. Higher levels of this type of fat have been linked to better concentration while performing demanding intellectual work (Lipids 2004 Feb; 39(2):117-23).

    Fats add flavor to food, making meals taste better. Monounsaturated fats like plain olive oil and canola are liquid at room temperature and are suitable for use in cooking at high temperatures. Researchers have found that a diet high in monounsaturated fat has the ability to decrease LDL (bad) cholesterol (J Nutr 2001; 131:1758-63). Other fats, such as extra virgin olive oil and flaxseed oil, are best used in dishes that don't need cooking, such as salads.

    Although the RDI for fat is less than 30% of the total calorie intake, some researchers believe that if you eat healthy fat, eating too much is not a concern. Omega-3 fats are available in supplement form.

    Wonderful Water

    Do you suffer from dry skin? You may not be drinking enough water. This precious liquid is used by every cell of our bodies and makes up 60% to 75% of our body weight. Water is important for kidney function. Researchers in Italy found that drinking adequate amounts of water can help prevent the formation of kidney stones (Urol Int 2004; 72 Suppl 1:29-33).

    Your activity level, environment and diet influence how much water you need daily. Try to drink at least eight cups of fluid a day from noncaffeinated, nonalcoholic sources.

    Voluptuous Vitamins

    Do you exercise frequently? If you do, you need more antioxidant vitamins like natural vitamin E and vitamin C as well as a healthy supply of carotenoids. A study at the School of Applied Medical Sciences and Sports Studies, University of Ulster, found that exercisers need more antioxidants. Otherwise, their exertion may release an excess number of free radicals (caustic molecules) in their bodies and do damage to the heart arteries and other internal organs.

    Vitamins, in general, are defined as micronutrients that are necessary for life. They are necessary for the production of energy, a healthy immune system and hundreds of other functions in the body.

    Vitamins aren't the only substances that produce big benefits in small quantities. Phytonutrients are chemicals in plants that have health-promoting properties. These nutrients are getting more and more attention from researchers who are keeping score on our nutritional requirements.

    Mineral Crunch

    Do your meals contain plenty of calcium? If not, you may need supplements to keep your bones strong and help keep your weight down. One study, presented at the Experimental Biology 2003 meeting in San Diego, found that young women who consumed more calcium had better luck controlling their weight. In this research, it didn't take much calcium to make a difference in waistlines. Consuming just one more serving daily (a cup of milk or a thumb-sized piece of cheese, each of which contain about 300 mg of calcium) made, on average, about a two-pound difference.

    In addition, many experts recommend multimineral supplements (along with multivitamins) to promote better health. A recent study of people with immune problems, for instance, found that those kinds of supplements seem to help boost the immune system (AT News 2004 Feb 27; 398:4-5).



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    Cancer at the Millenium - the war on cancer entering its third decade...
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    Date: June 13, 2005 10:23 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cancer at the Millenium - the war on cancer entering its third decade...

    Cancer at the Millenium by Harriet Brown Energy Times, May 1, 1999

    With the war on cancer entering its third decade, the necessity grows clearer for medical science to engage the enemy on several fronts. Until recently, high-tech medical weapons like vaccines and gene therapy, inspired by a flood of insights into the molecular basis of cancer, garnered most of the hope, hype, headlines and research money. The science was sexy and the prospect of a "cure" dramatic. But, today, advocates of prevention receive equal, if not greater, attention.

    Improving our diets and prudently supplementing with vitamins and minerals, can deliver a major preventive impact. Contentious experts concede that at least a third (and probably more) of all cancers can be blamed on a combination of eating too much of the wrong foods and not enough of the right ones.

    The Dietary Difference

    Though cancer can progress rapidly once it leaps past its inception, it develops over many years and in several stages. Beneficial compounds in food and supplements may intervene along a line that runs from initial exposure to carcinogens to the final step into outright malignancy. Nutrients may: - counteract environmental poisons and the toxic byproducts of liver metabolism

  • - neutralize free radicals (which might otherwise cause carcinogenic mutations in DNA)
  • - boost the immune system
  • - inhibit enzymes that drive cell proliferation
  • - halt metastasis (cancerous reproduction)

    The Big Picture The dietary Guidelines advocated by the American Cancer Society and the National Cancer Institute (which generally coincide with those of most health organizations) may sound familiar: Eat plenty of fruits and vegetables. Get lots of fiber. Limit fat, especially animal fat. Go easy on meat and avoid the cured variety (they contain nitrites). If you drink alcohol, do it in moderation. Watch your total calories, and your weight. Pretty straightforward stuff.

    Carotenoid Characteristics

    Carotenoids, as their name suggests, are orange and red pigments in fruits and vegetables, most notably carrots and tomatoes, although they're also in everything from sweet potatoes to spinach and brussels sprouts (in the latter their distinctive color is masked by green chlorophyll).

    Lycopene, a carotenoid found primarily in tomatoes, displays double the free radical-fighting activity of beta carotene, the most widely studied carotenoid. Of 72 studies looking at consumption of tomatoes or tomato-based products reviewed in the February 1999 Journal of the National Cancer Institute, almost half showed a significant reduction in one or more of a variety of cancers.

    Research shows that lycopene may be best at lowering a man's risk of prostate cancer. A 1995 Harvard Medical School study (Journal of the National Cancer Institute 1995; 87: 1767-76) queried nearly 48,000 male health-care professionals about their consumption of fruits and vegetables. The only foods that reduced their risk of prostate cancer were, apparently, tomato sauce, tomatoes, pizza (tomato paste). For those who ate ten servings a week, risk dropped 45 percent; with four to seven servings, 20 percent. In animal studies lycopene decreased the number and size of mammary tumors (Eleventh International Symposium on Carotenoids, 1996).

    Tomatoes are one of the richest sources of lycopene. Cooking tomatoes helps by releasing the lycopene from the plant cell walls. Also, the oil in tomato sauce enhances absorption in the stomach. Lycopene is also available in supplements.

    Unreserved Resveratrol

    Wine drinkers rejoiced when resveratrol, a constituent of the skin of red grapes, was found to protect their hearts (by blocking oxidation of LDL cholesterol and discouraging blood clotting). Now they have another reason to toast this potent antioxidant. When researcher John Pezzuto at the University of Illinois at Chicago screened about 1,000 plants for anticancer activity, he came up with one whose active ingredient turned out to be resveratrol. In lab tests it squelched both free radicals and inflammation, two well-known cancer inducers (Science, 6/10/97). In a study with mice, resveratrol reduced the number of skin tumors by up to 98 percent compared to control animals. Because the effective doses were high (Pezzuto estimates a person would have to quaff about five gallons of wine a day to get the equivalent) and because more than a drink or two a day may raise the risk of breast cancer, researchers don't recommend nondrinkers take up wine. But supplements of synthesized resveratrol (as well as grape juice) may help.

    Fat Chance

    Saturated fat is an authentic dietary villain. Aside from clogging arteries, it's a suspected contributor to several cancers, though the evidence is greater for some cancers (prostate) than for others (breast cancer)

    Of the two other main categories of fats, monounsaturated and polyunsaturated, mono seems benign, if not positively protective. For example, in a study of the influence of diet on breast cancer, Greek researchers discovered that women who consumed higher amounts of olive oil (which is mostly mono) were less likely to be afflicted with breast cancer (Journal of the National Cancer Institute 1995: 87; 110-116).

    When it comes to polyunsaturated fats, however, things get complicated. The fat that predominates in corn, sunflower and other vegetable oils, called omega-6, has long been associated with cancer risk in animal experiments. Likewise the type found in margarines, trans fats, which are partially saturated vegetable oils. On the other hand, the omega-3 fats called EPA and DHA, which are found primarily in deep- and cold-water fish like cod, mackerel, and halibut, protect against both heart disease and cancer. In an epidemiological study covering 24 European countries, British researchers established that mortality rates for colon and breast cancers declined as fish and fish oil consumption rose (British Journal of Cancer 1996: 74; 159-64). And Finnish scientists discovered that the breast tissue of women who had breast cancer contained significantly less DHA and EPA than the breasts of healthy women (Nutrition and Cancer 1995: 24; 151-160).

    Experts believe the omega-3s' anticancer effect derives from its ability to tamp down the prostaglandins that stimulate inflammation. Chronic inflammation unleashes a steady stream of free radicals, which can damage DNA and thereby trigger cancer. Omega-3s also help the liver detoxify potentially harmful substances.

    Fortunately for the fish-phobic, nonmarine sources of omega-3 fats include flaxseed and hemp oils.

    Minerals to Lower Cancer Risk

    n Calcium: possibly protective against colon cancer. In a recent trial (New England Journal of Medicine, 1/14/99) researchers gave people with a history of precancerous colon polyps either two 600 mg calcium tablets a day or a placebo for nine months and found fewer polyps. n Selenium: powerful antioxidant and supporter of immunity. Researchers find that cancer rates in various regions is lowered when soil and vegetables contain more selenium

    In a selenium-depleted area in China afflicted with one of the highest incidences of stomach and esophageal cancer mortality in the world, scientists asked different groups to take various combinations of nutrients. After five years they found a significant reduction in the cancer rate among those who had gotten supplements of selenium, vitamin E and beta carotene (Biological Trace Element Research 1985; 7: 21-29). In the U.S. researchers studying the potential effectiveness of selenium supplementation for preventing nonmelanoma skin cancers came up with a surprise. The 200 mcg a day the subjects received for an average of 4.5 years had no impact on skin cancer but did significantly cut the rates of lung, colorectal and prostate cancers (Journal of the American Medical Association, 12/25/96).

    More recently Harvard researchers determined that men with prostate cancer had much lower levels of selenium in their toenails (a measure of consumption) than healthy men (Journal of the National Cancer Institute, 8/119/98).

    Cruciferous Vegetables

    Cruciferous vegetables like broccoli, brussels sprouts, cauliflower and kale, have long been singled out for their association with protection against cancer. In a 1996 survey of 94 population studies and clinical trials focusing on consumption of cruciferous vegetables, 67 percent showed a reduced risk, the strongest link being with lung, stomach, colon and rectal cancers (Cancer Epidemiological Biomarkers 1996; 5: 733-748).

    Scientists at Johns Hopkins showed that sulforaphane, from these plants, stimulates enzymes that help detoxify carcinogens generated in the liver. When they injected rats with a cancer-causing chemical, only 26 percent of the rodents pretreated with sulforaphane developed mammary cancer, compared to 68 percent of controls. Even animals who did come down with cancer had tumors that appeared later and smaller.

    Other researchers have focused on a cruciferous-vegetable compound called indole-3-carbinol, which has proved especially effective against breast cancer cells. Recently, scientists at the University of California at Berkeley found that indole-3-carbinol, rather than acting as an anti-estrogen, (as had been thought), actually stops breast cancer cells by turning off a protein critical to their replication (Jrnal of Bio Chem, 2/13/98). Consequently, when treating certain forms of cancer, some doctors have paired indole-3-carbinol with the chemotherapy drug tamoxifen - which counteracts estrogen - and found that the combination has proven more potent than either separately.

    Fiber

    Several decades ago British physician Denis Burkitt proposed that the low incidence of colon cancer among native peoples in South Africa was attributable to the fact that their diet was rich in fiber. The fiber, it was hypothesized, bulked up the stool, speeding its passage through the bowel and reducing the time carcinogens contact its lining; it also helped neutralize cancer-promoting bile acids.

    This concept has been backed up by numerous studies. Recently, Harvard researchers sprinkled cold water on this idea, finding that an examination of the eating habits of more than 80,000 female nurses, could find no protective effect against colon cancer or precancerous polyps from consuming fiber (NEJM, January 21, 1999). Most experts' take on this apparent refutation: Maybe the "high fiber" intake in this case wasn't high enough, and this is just one study among many.

    Fighting Breast Cancer

    Fiber has also been linked to reduced rates of breast cancer. At first it was thought that if fat was a breast-cancer culprit, fiber might just be a marker for a low-fat diet. But a look at Finland undermined that idea: Finnish women eat both a lot of fat and a lot of fiber, and their breast cancer rate ranks much below that in the U.S., (where we eat gobs of fat and little roughage).

    Fiber helps take estrogen out of circulation as it passes through the liver, while the isoflavones in many high-fiber plants and vegetables are themselves weak estrogens, which compete for slots on breast tissue's estrogen receptors. The special fiber in flaxseed oil called lignans act against estrogen in two ways: by binding its receptors and by inhibiting the enzyme that converts other hormones into estrogen.

    Fiber comes in two basic forms, insoluble (e.g., wheat bran, celery, the skins of fruits and vegetables) and soluble (e.g., oat bran, citrus fruits, beans). Until a few years ago, scientists believed that cancer protection came mainly from insoluble fiber, but that thinking has turned around.

    A soluble fiber called citrus pectin has been shown to halt the tendency of prostate, lung, breast and skin cancers to metastasize, or spread (e.g., Journal of the National Cancer Institute 1995; 87: 3448-353). Typically cancer turns deadly only when it gets into the bloodstream and invades new territory. Modified citrus pectin appears to stop this aggression by preventing cancer cells from attaching to healthy tissue.

    Novel Antioxidant

    While the name inositol hexaphosphate (IP6) sounds like a mouthful, many of us consume mouthfuls of this natural substance every day - in foods like corn, rice, whole-grain cereals, oats and wheat.

    But now scientists have isolated IP-6 and found that this powerful antioxidant can slow the destructive cellular processes that lead to tumors. In a study published in Anti-Cancer Research (Nov/Dec 1998), scientists at the University of Maryland School of Medicine demonstrated that IP-6 could shrink liver tumors in laboratory animals.

    The researchers believe that IP-6 can help prevent cancer and also be useful in lowering the risk of health problems like kidney stones and heart disease. Research like this continues to expand our knowledge of how to lower the risk of cancer. In the next millennium, with more and more information making its way into the media and onto websites, our power and the responsibility to reduce our risk of cancer will continue to grow and offer new possibilities.



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    TopPreviousNext

    Date: May 09, 2005 06:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    It's in the Blood

    Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

    The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

    “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

    “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

    At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

    While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

    Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

    And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

    Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP Guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

    King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

    Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

    "Blur of Products"

    With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

    To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

    Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

    Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

    Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

    “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

    On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

    Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

    Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

    Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

    Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

    Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

    Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

    “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

    Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

    Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

    “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

    For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

    Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

    Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

    Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

    Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

    Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

    “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

    Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

    Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

    However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

    Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

    Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

    Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

    New Weapons

    There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

    With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

    Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

    “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

    Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/

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