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Curcumin and Grapeseed
September 01, 2020 11:03 AM
Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society.
Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone.
Two top suggested natural medicines available right now are curcumin and grape seed extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and grape seed extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous.
Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation.
Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells.
Curcumin Must Be Absorbed To Be Useful
One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil.
Curcumin Makes Chemo More Effective
There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells.
Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news!
Curcumin Protects The Body During Cancer Treatment
In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective.
The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement.
At the end of the treatment which lasted 20 weeks the most dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.
4 magical herbs that can help you lose weight faster
April 26, 2019 01:34 PM
We're constantly met with over-the-counter supplements loaded with chemicals and preservatives that promote claims of being able to shrink your waistline, but what if there were more natural options? Consuming ginseng helps regulate your blood sugar levels, as well as boost your metabolism. Garlic is almost a magical herb in how it is able to help you fight off cravings due to your body being able to sustain levels of fullness for longer periods of time.
"Those 7 days or 1-month weight loss challenges cannot give you a long-term result."
Read more: https://timesofindia.indiatimes.com/life-style/food-news/heres-4-magical-herbs-that-can-help-you-lose-weight-faster/articleshow/68283825.cms
Trace minerals from deep in the ocean found to increase blood flowand reduce inflammation in the brain
April 17, 2019 01:26 PM
Those who follow paleobiology have a deep belief that life started within the ocean itself. Right now, those who are highly active in physical activity typically rely on supplemental beverages that include a large amount of essential vitamins and minerals, but they often include a lot of preservatives as well. Fortunately, a recent study showed that athletes are able to thrive and preform just as well when ingesting discovery of deep ocean minerals (DOMs) through natural avenues.
"From this idea, scientists hypothesized that ingesting the minerals from deep ocean water may replenish incomplete molecular complexities and increase our physical capacity against energy-consuming and physically taxing challenges."
Read more: https://www.naturalnews.com/2019-02-11-trace-minerals-from-ocean-increase-blood-flow-reduce-inflammation.html
Here are some of the best vegan-friendly protein sources
January 27, 2019 04:33 PM
Vegan diets are something that is really in fashion right now. Years ago, very few people were following vegan diets. People did not pay much attention to it but now, due to social media and marketing, these diets are getting more and more hype. As a result, you should try to make sure you are getting all the nutrients you need when on this diet. It is only natural for there to be some kind of nutrient deficiency when on this sort of meal plan.
"Following a vegetarian or (the stricter) vegan lifestyle is rewarding, but it also comes with some challenges. Foregoing meat means you lose out on a major source of protein, but the list below includes other Paleo meat-free sources of this crucial nutrient."
Read more: https://www.naturalnews.com/2018-12-08-best-vegan-friendly-protein-sources.html
Gut microbes play a significant role in the central nervous system digestive health is linked to your risk of neurodegenerative diseases
August 07, 2018 09:53 AM
Neurodegenerative diseases like Alzheimers are becoming more and more common in the United States, and pose an increasing risk to aging populations. A recent study has identified gut microbes as one of the causes of these diseases - a huge breakthrough in the field, and one with significant implications for how we view our brain's health. These microbes release chemicals that can change the nature of the brain. It's a finding that shows that caring for our digestive health can be one of the most important steps to preventing diseases like Alzheimers, later on.
"They reached their conclusions after examining gut microbes and changes in mouse models of multiple sclerosis. They discovered the compounds produced by the breakdown of tryptophan cross the blood-brain barrier and activate an inflammatory pathway that can limit neurodegeneration."
Read more: https://www.naturalnews.com/2018-07-30-gut-microbes-play-a-significant-role-in-the-central-nervous-system.html
5 undeniable ways to protect your prostate
April 12, 2018 05:17 PM
Men are not as proactive as women in taking care of their health. One common problem men face is prostate problems, but 5 simple self care steps may help prevent problems before they arise. For the health of your prostate, consider the following lifestyle changes. Reducing stress, eliminating foods such as red meat, alcohol and processed foods from your diet, while adding foods rich in antioxidants. If you can't do this through diet consider using a targeted supplement for prostate health. And last, but never least, add exercise to your daily routine.
"Easier said than done, but not making it any less important, stress is a key element that promotes and exacerbates prostate related issues. This stress can originate from many different areas, but most often stems from unhealthy relationships, job settings, and financial challenges."
Read more: https://www.naturalnews.com/2018-04-10-5-undeniable-ways-to-protect-your-prostate.html
Craniosacral Therapy for Depression, Neck Pain & Headaches
November 01, 2017 10:14 AM
Craniosacral therapy can do a world of good for your neck pain as well as headaches you might be experiencing. The sacrum is a bone that has a triangular shape and it is located in your back. CST can have a very good impact on your mood and relaxation. The sacrum is connected all the way up to your head, so one can see how important it is to treat the body holistically. There is still debate on how craniosacral therapy helps to reduce pain.
"The underlying belief behind CST is that the human body is capable of self-healing, given the right tools and circumstances."
Read more: https://draxe.com/craniosacral-therapy/
Scientists: Children need microbes, not antibiotics, to develop immunity
August 22, 2017 05:14 AM
To vaccinate or not to vaccinate… that is today’s question. You will not find a more polarizing discussion in today’s world. Not even Trump can compare to this question. Parents, grandparents, caregivers, teachers, etc pick one side and one side only. Have you ever tried having a simple educated conversation on this topic? Attacks and attacks only are the product of that debate not doubt. Check out this video for a very interesting point of view. It challenges the notion that immunity can be created by microbes. Think about that for a moment, a totally new way for us to think about immunity.
"While we’ve known for decades that hand washing is important, for some reason, about a decade ago people started freaking out about dirt and started over sanitizing everything."
Cleanse, Detox or Challenge – Is one right for you?
July 18, 2017 12:14 PM
There are many health upside to a body detox. There are many steps to ensuring a strong a health life. One main benefit of a detox to to eliminate foods the do the body harm. Another benefit of a detox is to see which foods, you consume, effect the bodies functionality. The biggest problem, at first, will be a shock to the body. The shock takes place and you shift to liquid and prolonged lower calorie intake. The best detox will help you understand you body better, give you more daily energy, and give you a healthy life.
"just practicing the act of making changes can have a life long impact."
Read more: https://www.echoak.com/2017/07/cleanse-detox-challenge/
Jarrow challenges FDA on probiotics
June 05, 2017 11:14 AM
Jarrow Formulas Inc. has released a 32 page comment challenging the FDA on it's stance on probiotics. It notes how the FDA won't approve the term probiotics in several cases, instead using the phrase active cultures and just how the FDA labels probiotics in general. The company also takes issue with the fact that fermentation is considered chemical alteration under the current guidelines. The draft was vetted by the supplement company's lawyers and could dramatically change dietary guidelines if accepted.
Read more: Jarrow challenges FDA on probiotics
6 Easy Ways to Start Eating Vegan
November 12, 2016 09:54 AM
Eating a Vegan diet is desirable by many people. Not only is it good for you, the diet may also help you lose weight and feel better. No one will deny that making the switch to a Vegan diet is difficult, but with these tips, making the transition just become much easier. If you're ready to change your life, you need this information.
"Talk to vegans you know about how they transitioned, what challenges they had and how they overcame them, and what things they love most about their vegan lifestyle."
Do you need to regulate hormones ? Experience Chaste Berries Powerful Effects
Would you believe that a simple berry could be the solution to hormone normalization and regulation? The Chaste berry has been shown to treat suffering from symptoms of menopause, menstrual irregularities, pre-menstral syndrome, and infertility. However, Chaste berries benefits do not end with women as the berry has also seen use as a natural way to balance hormones in men and may actually prevent prostate cancer.
Chaste berry, also known as vitex, has the ability to regulate and stimulate anterior pituitary functions and has been shown to restore normal estrogen to progesterone levels in women. This is accomplished by attaching to dopamine receptors and decreasing output of prolactin. It is this process that allows Chaste berry to treat the multitude of different hormonal issues that it does and ultimately regulate and normalize hormone levels.
In conclusion, there are many different uses for Chaste berry when it comes to hormonal health. For women the berry has shown successful use as a treatment for PMS pains, fertility challenges, and abnormal menses. In men, Chaste berry has been used to prevent prostate cancer and balance hormones. Chaste berry has also been indicated to effectively treat acne in both male and females. Who would’ve thought you could get all that from one little berry?
Why Should We Take A Multi-Strain Probiotic?
Most people taking a probiotic supplement or drink do so for the purpose of supporting digestive health. Probiotics increase the colonization of beneficial bacteria in the intestines and limit the proliferation of pathogenic or disease-causing bacteria. A healthy intestinal microflora is believed to not only enhance digestion, but also promote general health and boost immunity.
Probiotics Offer More than Digestive Health Support
Probiotics offer medical advantages that go past the extent of supporting digestive wellbeing. Recent studies demonstrate that particular strains of probiotics may be utilized to treat particular conditions. Here's a rundown of advantages of taking probiotics supplement or drink:
Blend of Probiotics with Other Ingredients
Products that contain probiotics and a blend of different fixings are picking up prevalence since they offer more extensive advantages for wellbeing.
The symbiotic blend of probiotics with prebiotics multiplies the development of solid microflora. Prebiotics are insoluble fiber, for example, Fructooligosaccharides (FOS) and inulin, which achieve the colon in a genuinely undigested state. It is in the colon that probiotics feast upon prebiotics through a maturation prepare that happens in the colon. Amid this procedure, by-items called transient unsaturated fats (SFA) are delivered. SFAs help to keep up fundamental elements of the body and produce certain B vitamins.
Probiotics can be consolidated with proteins that help separate sustenance substances into easier structures to improve supplement absorption.
Consolidating probiotics with a multi-vitamin is famous yet stances challenges in assembling because of the touchy way of probiotics. Probiotics are delicate to light, dampness, heat, oxygen.
How Probiotics Manufacturers Can Provide Retailers with Reliable Probiotics Supplements
The greatest test that probiotics producers face is keeping the microorganisms alive amid the mixing procedure while guaranteeing strength amid timeframe of realistic usability. At the point when joined with different fixings that are similarly touchy, for example, proteins, compelling consideration ought to be taken to guarantee that the assembling and bundling procedure happen in a dry situation. Any dampness may initiate the proteins and wreck the probiotics.
Microencapsulation is a genuinely late innovation that guarantees the survival of probiotics amid surrounding so as to assemble and stockpiling it with an external covering. Microencapsulating shields probiotics from ecological defilement and forestalls unplanned blending of probiotics with different fixings in the recipe that may bargain its solidness.
Guaranteeing the Right Strain and Count
The wellbeing presenting advantages of probiotics are strain-particular. Diverse strains have particular capacities in the body and not all strains are valuable to wellbeing. Probiotic formulators must be knowledgeable in probiotic strains and the utilization of proper strains for the sought condition-particular capacities. Slight variety in the hereditary profile of strains could create undesirable results.
How important is it to take a GLA supplement?
December 04, 2013 06:43 AM
How important is it to take a GLA supplement?
Majority of people consider evening primrose oil as one of the major miraculous discoveries within preventive care after Vitamin C. This oil consists a compound called phenylalanine that can assist with pain relief and has been applied increasingly with remedying headaches. Its therapeutic and preventive features are many hence making it a regular proposal from a big number of herbalists.
10 health benefits:1- GLA Deficiency
Evening primrose oil has a lot of fatty acid gamma linolenic acid (GLA) which is very crucial for general operation of the body.
2- Heart Health
Studies revealed that utilizing of evening primrose oil on daily basis can assist in lowering blood pressure, cholesterol and safeguard against the coronary artery disease thus minimizing the capability of heart attacks and diseases.
3- Menstrual Pain
The oil is normally used in relieving distress that is normally related with menstrual signs. Majority of women around the world get relief by applying evening primrose oil.
Diabetics occasionally get challenges in producing GLA hence evening primrose oil is an effective supplement to assist them. Studies revealed that this oil can also safeguard people from diabetic neuropathy which is a nerve condition that often affects diabetics.
5- Skin Health
Evening primrose oil is considered as an effective remedy for eczema and other skin disorders due to GLA and other essential fatty acids that are vital for skin health.
6- Anti-Inflammatory & Discomfort Reliever
Evening primrose oil is referred to contain anti-inflammatory features and can assist to ease symptoms of chest discomfort and rheumatoid.
7- Attention Deficit Hyperactivity Disorder (ADHD)
Studies revealed that kids suffering from ADHD got relieved after taking evening primrose oil.
8- Chronic Fatigue Syndrome
Utilizing evening primrose oil with quality fish oil is an effective therapy for chronic fatigue syndrome.
9- Helps to Counter Impotence & InfertilityEvening primrose oil can stimulate blood flow, thus it helps in solving one of the key causes of male impotence. When taken for some time, it assists in preventing blood vessels to become narrow as a result of cholesterol.
10- Helping with Alcohol Withdrawal Symptoms
The GLA prompts the brain to make a specific type of prostaglandin called prostaglandin E that can operate to resist withdrawal symptoms.
How Does Now foods Test For Quality In Raw Materials?
October 26, 2011 10:44 AM
How Does Omega-3/6/9 Help My Cat And Dogs Hair Health?
September 23, 2011 12:50 PM
A man's best friend as we all know them, and yes, I do mean both dogs and cats, I know we would commonly refer to dogs when it comes to that saying but I can make an argument about cats being a man's best friend too. Although I won't get into details about that in this article, no room for that argument for the moment. Rather we are going to talk more about their health or Hair Health to be exact. We've all had that experience right? An owner of any of the two pets, may it be a new sofa, a new car or maybe a new bed, will experience hairs everywhere. Well one way to improve that situation and I'm not saying that it will cure it completely is to focus more on how to help enhance your pet's hair health.
How many times have you heard someone referring to a dog as a sick one due to poor fur conditions? A lot probably, because it is true, the fur is most definitely one of the ways to tell whether a pooch is healthy. I understand, you might be saying that hair loss among dogs is usual and in fact, they do have seasonal shedding. And I am not disputing that fact, like I said earlier we will not be able to stop shedding entirely because of that very reason, it is part of a dog's biological process. However, it does not mean we could not lessen it especially when it is not part of their seasonal shedding. But before we get there let's talk about the other half of this match made in heaven.
A little fur ball here and there, who hasn't seen that? Cats do shed hair and they do it all throughout the year. The amount of shedding is determined by a couple of things, its health, its nutrition and in some cases where it lives. Its environment does play a factor, like the weather or whether it is an outdoor cat or an indoor cat. But we can influence a couple of those possible reasons for shedding.
Omega 3/6/9 and Hair Health
These omega fatty acids are one things that could help us with the hair shedding challenges that our adorable pets give us. Aside from usual regimens of brushing and other tips to improve hair health, supplementation of these omega fatty acids could be of great help to you. Here are some of the reasons why.
Omega 3 has Alpha Linolenic Acid, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These substances are essential in the optimum functioning of our pet's central nervous system and aids in the protection of skin from diseases.
Omega 6 also contains linolenic acid and arachidonic acid, and has anti - inflammatory properties and helps promote healthier skin, hair and nails.
Omega 9, also known as oleic acid is a precursor of the other essential fatty acids which is the primary reason for its importance.
Glutathion, Antioxidants, And The Body
July 14, 2010 02:41 PM
Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges.
Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis.
A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids.
The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell.
Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion.
Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well.
Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.
Fight Inflammation With Herbs from Planetary Herbals
June 02, 2010 04:39 PM
Our modern lives have untold benefits, as well as challenges. Our dependence on man-made toxic chemicals, junk food, nutrient imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health.
These lifestyles and environmental change can challenge immune health, so that the various components of the immune system are not able to carry out their protective functions. Or our immune systems can go into overdrive, often leading to a state called metabolic inflammation.
A Powerful Herbal Blend
Inflamma-Care is a potent, herbal response to the metabolic inflammation that can result from inappropriate immune response. The main component of inflama-care is the rhizome of the curcuma spicies, long used as a spice in India. Known worldwide as turmeric (curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines – inflammation messengers.
This world-renowned spice is supported by boswellia, which inhibits pro-inflammatory enzymes, and ginger an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skullcap, corydalis, holy basil, and hops.
Inflama-care also contains systemic enzymes to clear and protect the arteries and circulatory system. Systemic enzymes like bromelain and papain cleanse the bloodstream and enable the blood to flow smoothly. A free-flowing bloodstream helps the body by circulating important nutrients to the cells while clearing the body of wastes.
Immune Activating Mushroom
Planetary Herbals also offers you new Full Spectrum Chaga in 1000mg tablets and a 1:4 liquid extract. Preliminary studies suggest that chaga triggers immune responses and protects the cells with antioxidant activity.
Chaga is a mushroom that is found attached to trees like birch, alder, beach, and other hardwoods, throughout the northern latitudes. A polyphore, the mushroom looks somewhat like coal – a brownish black mass often seen in tree trunks. In China, Siberia, Finland, Japan, Poland and North America, ancient and native peoples have long known the benefits of chaga. In an acient treaties, the Chinese monk shen nog declared in 100 BC that chaga is “a precious gift of nature.”
In modern research, chaga has been shown to have 215 phytonutrients, including 29 beta-glucans. Chaga also absorbs a nutrient from the outer birch tree bark: betulin, a natural anti-inflammatory. Among the components in chaga are triterpenes, sterols, beta-glucans, flavonoids, melanins, polyphenols, saponins, lignin, amino acids, vitamins, minerals, and fiber. This fascinating combination of nutrients is being studied worldwide.
The PhytoDynamic Difference
Both inflama-care and full spectrum chaga are formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. The result: herbal products unsurpassed for quality and consumer satisfaction.
Vitamin A Vs Beta-Carotene and its Safety
May 09, 2010 08:20 AM
Although Vitamin A deficiency is prevalent throughout the world, retinol toxicity is a common occurrence as well. About five percent of those who supplement with vitamin A unknowingly suffer from toxicity symptoms. It should be noted that supplementation at 5,000 to 10,000 IU per day of preformed vitamin A, which is dose that is well within the range that is offered in many popular vitamin supplements is a safe effective doses, additional supplementation of vitamin A may actually lead to a cumulative toxic overdose. Additionally, accidental ingestion of one single, large dose of vitamin A, can produce acute toxicity in children, always keep vitamin A out of reach of small ones.
A large study on over 22,000 pregnant women who supplemented with vitamin A during early pregnancy found that those women taking more than 60,000 IU of preformed vitamin A per day in the form of supplements had about one in fifty-seven of a chance of a malformation attributable to the supplement. In consuming more than 60,000 IU of vitamin A, a five-fold greater risk for birth defects arises as compared to consumption of less than 25,000 IU per day. The prevalence of birth defects seems to be greatest in those women who consume high levels of pre-formed vitamin within the first seven weeks of their pregnancy. Authors of the study concluded that women who may possibly become pregnant should limit their retinol intake to below 15,000 IU, or supplement with beta-carotene instead.
Beta-carotene is the orange/yellow-colored pigment that is often found in many garden vegetables. It is a retinal precursor. The body is able to easily convert beta-carotene into vitamin A by turning the carotene molecule into two molecules of retinol as they are needed. This allows for the avoidance of toxic accumulation of pre-formed vitamin A. Once beta-carotene is transformed into active retinol, it offers the same beneficial affects. The only symptoms associated with beta-carotene supplementation are loose stools or slight discoloration of the skin. This makes beta-carotene, even at high doses, safe for the body because it does not exhibit toxicity. An added benefit of beta-carotene is that it is a much more potent antioxidant than retinol, as it provides even greater protection against oxidative challenges. The worst thing that can happen to you if you take too much beta-carotene is that you may turn orange like a carrot. However, this should not be a worry because you will be just fine.
The majority of nutrients that are used in supplementation have a large measure of safety. Unfortunately, the use of vitamin A warrants prudence and caution. This is especially crucial when it is consumed by children or those women who are pregnant. Because of this, the level of vitamin A in excess of the upper limit of intake that is prescribed by the Food and Nutrition Board of the Institute of Medicine, is a crucial criterion in determining how good a product is. The criterion for potential toxicities asks whether the nutritional supplement contains vitamin A. If so, it asks whether the potency of vitamin A exceeds 100% of the upper limit of intake that is prescribed by the US Food and Nutrition Board.
To be on the safe side, take beta-carotene which has no side effects even at very high doses but exhibits the same health benefits of consuming preformed vitamin A. Look to your local or internet vitamin store for name brands like Solaray and Source Naturals for all your Vitamin A and beta-carotene needs.
The Good and Bad of an iron supplement
April 25, 2010 06:04 PM
Iron holds a crucial role in the physiology of the body. It is a central part of the haemoglobin and myoglobin molecules. Iron is indispensable to the body’s ability to transport gases into and out of the cell. It is necessary in many important enzymes that are involved in energy production, metabolism, and DNA synthesis. Some iron is lost when red blood cells are broken down and excreted in the bile. However, because of iron’s importance, the body is able to conserve iron at all costs, as the kidneys do not eliminate the metal.
The dark side of iron supplementation comes when iron is consumed in amounts that are excessive to the body’s needs. Although unbound iron is more likely to cause oxidative challenges through the generation of free radicals, excessive iron supplementation in any form can cause huge problems for the cell. The overload of iron can cause deterioration of the gut lining, vomiting and diarrhea, abdominal and joint pain, liver damage, loss of weight, and intense fatigue. In children, acute doses as low as 3 grams can cause death.
About one out of every 250 North Americans suffer from haemochromatosis, which is a genetic defect that is common in a lot of those people of northern European descent. This disorder causes the body to accumulate and abnormally store high levels of iron. Those people with haemochromatosis store twice as much iron as others, which places them at increased risk for iron-related diseases. Symptoms of these diseases generally occur after fifty years of age and often include things ranging from fatigue, abdominal pain, achy joints, impotence, and symptoms that mimic diabetes.
Several studies have produced evidence which suggests that high levels of iron contribute to noticeable increases in the risk for cardiovascular disease. This is likely due to non-haeme iron’s aggressive pro-oxidant nature. Iron levels are one of the strongest biochemical markers for the progression of atherosclerosis, which results from increased oxidation of LDL cholesterol. A study in 1995 conducted on Finnish men found that those who had high body stores of iron also had a substantially increased risk of heart attack. Those men who posses the highest levels of stored iron often showed a levels of risk that was up to three times that of men who possessed the lowest levels of stored iron.
Disorders in iron accumulation contribute to a whole host of other disease states, all of which are degenerative in nature. Studies have shown that chronic iron overload contributes to increased infections, cancer, arthritis, osteoporosis, diabetes, and various congenitive dysfunctions. The only way to remove excess iron is through blood letting, unless you are a woman with regular menses. That is why, for men, iron overload can provide quite a problematic issue. Recent research has found that long-term supplementation with iron at doses less than 5 mg/day can lead to iron-overload toxicity. Because of this, it is recommended that the upper limit of iron intake be at 5 mg/day when considering a product’s rating. Any product that contains iron at a daily dose greater than this limit is penalized with this rating criterion.
But for those who need iron, it can easily be obtained through a vitamin supplement at your local or internet health food store. Men should avoid iron supplements and products containing iron, but women on the other hand due to monthly blood loss should supplement with iron regularly.
Fight Inflammation With Inflama-Care - Anti-inflammatory herbal combination
March 22, 2010 09:07 PM
Turmeric / Boswellia Complex
Our modern lives have untold benefits, as well as great challenges. Our dependence on man-made toxic chemicals, junk food, nutrient-imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health. These unhealthy lifestyles and environmental changes have set our immune system on overdrive, a state call metabolic inflammation. Planetary Herbals Inflama-Care is a potent, herbal response to these modern challenges.
The Inflammation Cycle
As toxins and stress begin to alter our body chemistry and change the function of vital tissues, our body reacts with metabolic inflammation just as if it were being attacked. This reaction may result in a perpetual cycle of chemical imbalances and suboptimal health. Yet metabolic inflammation is often below the threshold of perception, not noticed or felt for years after its starts. It is only much later that the altered biochemistry and the system imbalances that it generates are noticed.
A Powerful Herbal Blend Inflama-Care helps support the body’s natural response to metabolic inflammation. The main component of the formula is the rhizome of the curcuma species, long used as a spice in India. Known worldwide as turmeric (Curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines—inflammation messengers. This world-renowned spice is supported by boswellia, which inhibits proinflammatory enzymes, and ginger, an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skull cap, corydalis, holy basil, and hops.
The PhytoDynamic Difference
Planetary Herbals presents inflama-Care to help maintain the body’s biochemical balance and integrity. Inflama-care was formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. Thie result: herbal products unsurpassed for quality and consumer satisfaction.
Now foods and GMP Practices
February 04, 2010 12:36 PM
Author: Michael Lelah, Ph.D, Technical Directory, Now Foods
It should come as no surprise that 2009 was a challenging year with regard to the timeliness of order delivery, not just at NOW, but on an industry-wide scale. Many of the brands you carry have not been able to meet your demands.
In 2009 all medium-sized dietary supplement manufacturers, including NOW Foods, were officially required to meet the FDA's new dietary supplement cGMPs (current good manufacturing practices). NOW has placed very high quality standards on our products, and has been certified by NPA's stringent GMPs since 2000. Now that the FDA has started auditing manufacturers in our industry, we have found that the FDA requirements for the cGMPs are more strict than the early interpretations of experts.
This has resulted in ourselves and our industry being less prepared than anticipated, affecting the order fulfillment rates of many companies. We are actively working to respond to this.
Let's review the new FDA cGMPs. Good Manufacturing Practices, or GMPs, are manufacturing control systems designed to ensure that health products are manufactured in a consistent and safe manner. Standard operating procedures, specifications for all ingredients and products, and lab testing are cornerstones of GMPs. The FDA cGMPs are considerably rigorous, and by the FDA's own estimates, 25% of the brands you carry could be out of business as a result of not being able to meet their new cGMPs. Moreover, even for reputable brands, there is a lack of clarity on what the FDA expects, as much of this is new.
You might be wondering what all of this has to do with your orders? We at NOW Foods, along with other reputable manufacturers have increased our quality control efforts to meet the new FDA cGMPs. There are more requirements for ingredients and finished products, more documentation and more testing. The breadth of NOW's product line requires testing of thousands of ingredients. Based on the extensive nature of these efforts, coupled with disruptions in the supply chain, your orders have most likely been affected.
We are now better prepared to serve you. We are taking the safety of our products to entirely new levels and doing everything in our power to expedite the delivery of NOW products to your door.
Here are just a few examples of what we're doing:
Here's what you can expect from NOW Foods in 2010:
At NOW Foods we are continuing to work hard to meet your needs, despite the increased challenges to our supply chain. We hope and anticipate that as we move into 2010, you will reap the benefits of our quality and fulfillment efforts.
Natural Soap Bars
January 20, 2009 09:34 AM
With the earth-friendly topic being on so many people’s minds lately, consumers are realizing that using natural personal care products is a simple way to start with a greener lifestyle. Consumer demands for natural personal care products has actually experienced double digit growth consistently for the past few years, with this trend not expected to slow. At the same time, non-natural personal care is typically seeing less than a five percent growth.
Natural is currently one of the fastest growing subcategories of personal care, with a large crossover clientele emerging and many mass, grocery, and drug stores are now offering natural products. Success has moved natural ingredients into mainstream brands, opened doors to food, drug, and mass merchant distribution, and driven major consumer brands to enter the market. Larger mass market companies are now realizing the extreme growth potential and profitability of the natural market as compared to the traditional personal care market.
Manufactures have been trying many different things in the soap market including making soaps for sensitive skin, using fair trade ingredients, and discovering new ways to make creamier and more moisturizing soaps. Consumers are looking for their natural personal care products to have the same easy use and performance level of chemical-based personal care products. There is also an increase in interest in using food-based ingredients, as it is appealing on a consumer level due to the familiarity, because if you can eat it, it must be safe.
Fragrance-free and sensitive-sin products are also on the rise, with thirty percent of the population reporting some sensitivity to fragrance, while more than eighty percent report that exposure to fragrances is bothersome, with many synthetic fragrances containing phthalates, which are linked to birth defects and health-related issues. However, the consumer must know that there is actually a difference between unscented and fragrance-free. Unscented products mask the odor of the actual formula with a fragrance, which leaves the potential for skin irritation and allergic reactions.
The Natural Products Association recently launched a Natural Care Product Seal and Standard so that consumers could more easily identify products with truly natural ingredients. Adhering to these requirements can prove difficult for manufactures of natural soaps. Soaps and creams present several challenges to formulators who are seeking to avoid chemicals and synthetic materials. Soaps made according to the above standards will cleanse skin and hair, although they may have an appearance and texture that was different than many consumers are use to. These soaps may be thin, create minimal foam, and may have a shorter shelf life than other natural products that are made according to alternative ingredient standards.
Although bar soaps are staple products year round, liquid soaps are currently gaining popularity, as bar soaps are often drying to the skin and have a high pH. Liquid soaps, on the other hand, have a pH closer to that of skin and also have the ability to moisturize. The market should see an increase in liquid soaps in the future, as the population ages and skin is drier and needs more moisture, leaving the moisturizing abilities of liquid soaps to meet these needs.
November 06, 2008 10:09 AM
Anxiety responses were needed in previous years to trigger the nervous system into a series of chemical reactions that would initiate action. For our ancestors, this fight or flight impulse often meant the difference between death and survival for another day. Experts warn us that the never-ending stressors that we are constantly encountering can lead to health problems including obesity, diabetes, and hypertension. In contrast to the ancient forms of stress, such as the stress of a hungry bear approaching a cave, modern-day stress sources are more frequently of the chronic variety such as meeting increasing demands at work, studying for an exam, quitting smoking, and worrying about money and relationships.
Anxiety can wreak havoc on the overall health of children, with school work, exams, peer pressure, video games, and other challenges tending to trigger the same self-protective response that adults experience. However, in children, the result is often poor sleep. As a society, it is definitely evident that we need to unwind. The National Sleep Foundation reported that almost 74% of all Americans don’t sleep enough with the Centers for Disease Control and Prevention claiming that 50 to 70 million people suffer from chronic sleep disorders. Americans actually filled 35 million prescriptions for sleeping pills in 2004 costing $2.1 billion.
All of these previously listed signs indicate how easy it is for us to forget the importance of good rest. Thankfully, there is a solution: Lactium, which is a milk-derived protein that presents a natural alternative for those who suffer from the modern ills that are associated with stress. Lactium is clinically proven to aid with relaxation and stress reduction. It first attracted attention after researchers found the bliss of an infant after drinking milk. The question to ask is why milk does not produce the same blissful state in adults.
A decade of research has led to the conclusion that there is a peptide with relaxing properties within a milk protein called hydroslysate. Following studies confirmed this link between Lactium and the reduction of stress symptoms. Scientists also found that adults do not experience the same calming effects of milk that infants do is because adults do not have the same enzymes that are found in a newborn which allow for the release of this relaxing peptide. Lactium supplements overcome this problem, as Lactium was proven to reduce stress reactivity in healthy women who took it for thirty consecutive days.
Following these results, a multinational team of researchers investigated the effects of Lactium on women who exhibit at least one symptom of stress. The team concluded that a 150 milligram dose of Lactium per day was especially helpful for those people who had exhibited the highest of stress intensities. These women also experienced improved digestive, cardiovascular, intellectual, emotional, and social functioning.
Most experts agree that the best cure to stress is exercise and a healthy diet. However, many people under stress need a little extra help now and then. Lactium presents a safe, non-toxic, and 100% natural option for those people who want to maximize the quality of their sleep and relaxation. Lactium can help you find some of that sleep that nourishes your life and gives you the energy to take on another day. It is available at your local or internet vitamin store.
Celery Seed Extract Standardized
October 30, 2008 05:36 PM
Despite being relatively unknown within western medicine, Celery (apium graveolens) has been cultivated as food and used to promote good health for thousands of years throughout the world. In its earliest applications, Mediterranean and Ayurvedic practitioners relied on celery to address a wide range of health concerns, including respiratory challenges, fatigue, and physical distress. Some of the most recent scientific studies, however, have identified a number of potentially beneficial active compounds in Celery, including volatile oils, flavonoids, coumarins, and linoleic acid. One of the most significant and promising is 3nB (3-n-butylphthalide), the compound that gives celery its distinctive taste and aroma. The celery seed extract used in this formula is standardized 85% total phthalides calculated as 3nB. Studies have shown that 3nB appears to help support a normal inflammatory response and blood pressure within the healthy range. Additionally, research has suggested that 3nB may be able to increase cranial blood flow.
Celery Circulation is an innovative circulatory support formula designed to encourage a balanced inflammatory response while increasing blood flow through its vasodilatation properties. For enhanced support, it includes standardized extracts from horse chestnut (minimum 20% total triterpene glycosides) and hawthorn (minimum 1.8% Vitexin).
Immune Boost Herbs
September 17, 2008 11:16 AM
There have been numerous improvements to our quality of life over the last century with advancements in science and medicine. Most families in America have access to healthcare and tools which promise improved health and well being. Even with the benefits and comforts that living in the modern world provides, chronic and preventable illnesses continue to occur. The fast-paced and high-stress lifestyle that many Americans live impacts their health in a variety of ways.
We face more health challenges today than ever before, which makes it more crucial than ever to have a balanced immune system, something that many Americans lack. Although the US leads the world in quality of healthcare, an increasing number of people are suffering or dying from preventable health problems. The environment, lifestyle, genetics, age, and antibiotic resistance are just some of the factors that are to blame for this. Thankfully, boosting immune power can counteract the negative effects of these factors on health.
Most Americans do not sleep enough, do not eat right, and do not exercise like they should. Many of the most common health problems people suffer from today are a result of lifestyle. These problems include hypertension, heart disease, diabetes, cancer, depression, and unbalanced immune function. Despite this fact, Americans continue to take part in poor health habits and then give up billions of dollars in prescriptions, doctor’s visits, and surgeries each year when they encounter an illness.
A sedentary lifestyle is a major cause for disease, as inactivity and obesity are both potential risks. Exercising as little as three times a week has been proven to enhance well-being and improve health. A lack of exercise can also contribute to stress, which we all experience. However, a healthy immune system can make our bodies more capable of withstanding the effects of stress. If immune systems can be balanced, Americans may be better able to withstand the potential health problems that living in the modern world brings.
We must take into account the fact that more health problems can arise as we age. Older individuals are much more susceptible to disordered immune systems, as the progressive immune system dysfunction that coincides with aging has been shown to influence an increasing number of age-related disorders such as Alzheimer’s, osteoporosis, and late-life lymphoma. With this knowledge, we should want to supplement and strengthen our immune systems, especially as they get older. We can work to avoid the occurrence of autoimmune disorders and cancers that so commonly occur as we age by keeping our immune systems strong and functioning at optimum levels. A lot of the potential health problems that we are facing today can be traced back to the environment. One environmental problem is the result of toxic chemicals, as the widespread use of pesticides and increase of benzene and other pollutants in the atmosphere are leading to cancer and other reproductive health problems such as endometriosis and fertility issues.
The chemical pollutants in our air, food, and water have been linked to asthma, allergies, autoimmune disorders and weakened immunity. Additionally, we are being exposed to increasing amounts of UV radiation, with occurrences of skin cancer continually rising. Researchers believe that one of the main reasons for the increasing number of melanomas may be due to people spending more time in the sun as well as artificial sources of UV radiation. There are many herbs available to help boost the immune system and detox the body to help one keep a strong immune system.
August 26, 2008 04:58 PM
GABA is gama amino butyric acid, and is an inhibitory neurotransmitter that is essential for the proper function of your brain and the central nervous system, and has the effect of reducing excessive brain activity and promoting a state of calm.
For many people, the rush of daily life, with its problems, worries and external stimuli, can over-stimulate the brain to the extent that it can all seem too much for them. They feel anxious and overwhelmed, and wish that they could just go into a quiet corner to get away from it all. Most people have felt like that at some time, but the demands of life do not allow them that luxury. They just have to bear it and get on with life.
That is where GABA can come in. It can be used to bring your nervous system back to base, and make you feel more relaxed, calmer and more able to meet these challenges that life often throws at you. When you feel that you just can’t relax or concentrate on what you are doing, GABA can help you. If you look around you and everybody else seems OK, without apparently feeling the stress and irritability that you feel, and then perhaps your problem is due to a GABA deficiency. GABA is the principal inhibitory neurotransmitter in your brain, and a deficiency would certainly give you the symptoms that you are feeling. Let me explain why.
As your brain becomes excited, it can run out of control and needs some form of modification or inhibition to keep it acting as normal. Without this you would become increasingly more restless and irritable, and ultimately have seizures. GABA is not only the main inhibitor in your brain, but also helps in the production of endorphins that provide you with a sense of well being. That sense of calm you feel when endorphins are produced, for example during exercise or sexual intercourse, is commonly referred to as the ‘endorphin effect’.
GABA is at its highest concentration in specific areas of the brain, including the hypothalamus, the hippocampus and the central brain area, and is present in up to 40% of all synapses, the small gaps between neurons across which brain cells can communicate with each other.
It is produced during the Krebs or Citric Acid Cycle that is responsible for cell respiration or the production of energy from carbohydrates. It is synthesized from alpha-keto glutarate, which is produced just before the Succinyl Co-A stage of the Krebs Cycle in the brain. Vitamin B6 in involved in its metabolism, and a Vitamin B6 deficiency can lead to a deficiency in GABA that might result in seizures.
Basically GABA works by inhibiting the firing of neurons in your brain, and thus reducing general brain activity. The GABA receptor allows more chloride ion to enter the brain cell, thus helping to maintain the electrical charge within the cells. Bezodiazepines (e.g. diazepam) work by increasing the effectiveness of GABA in opening the chloride ion cells to allow more chloride ion to enter the neurons, and caffeine does the opposite, and inhibits this property of GABA. Thus diazepam works as a minor tranquilizer and caffeine as a stimulant.
Alcohol has a similar effect to the benzodiazepines, increasing the release of chloride into the neurons, and is the major way in which alcohol affects the brain. In fact, tolerance to drugs and withdrawal symptoms can be explained by the receptors adapting to the drug. They may increase in number, which means that more of the drug is needed to work on them, and they can become hypoactive in the event of the drug being withdrawn, that enhances the symptoms that the drug was intended to treat.
So basically, that is the way that GABA works. In simple terms it increases the flow of chloride electrolyte to the brain, and in so doing affects our mood. This effect is enhanced by prescription drugs such as Valium and Ativan, which are used by those that suffer the effects of a GABA deficiency. However, these drugs have side effects, not the least of which is dependency due to the GABA receptors becoming modified to suit the drug. There is a more natural way to overcome many stress problems and symptoms of mood swings.
Knowing what causes these symptoms, it makes sense to eat foods that stimulate the creation of neurotransmitters to replace those that are deficient. Since GABA is produced in the Krebs Cycle and complex carbohydrates produce glutamine that is an important part of that Cycle, and is also the precursor to GABA, then the consumption of such foods should in theory produce more GABA. In this case the theory works, and you should eat foods rich in complex carbohydrates such as whole grains, brown rice and oats as part of your diet.
Other foods that are high in glutamine or its precursors, glutamic acid and glutamate, include citrus fruits, beef liver, broccoli, halibut and lentils. A useful supplement to take is L-theanine, an amino acid found in green tea, and available in supplement form. L-theanine can calm your nerves while maintaining clarity of thought. In other words it calms you down, but doesn’t make you drowsy and allows you to enjoy your day with anxiety.
Your doctor can determine whether or not you have a neurotransmitter deficiency through a simple urine test, and might also test your saliva for hormone content. A GABA supplement might be indicated, and if so it other beneficial effects on your body other than its effect on your brain cells.
It improves your sleep cycles and promotes vivid dreaming, and can also have a positive effect on your blood pressure. It is also an effective pain killer, and can provide relief from such conditions as back pain and arthritis. Its stimulating effect on the anterior pituitary gland to secrete Human Growth Hormone might also be regarded as a benefit by many. Increasing the level of HGH in your blood can lead to fat loss and improved anabolic activity (increase in muscle tissue). This can be of benefit to older people whose level of HGH secretion has dropped off, and who find it more difficult to lose fat.
GABA is a substance that has many known benefits and no known side effects other than a slight tingling and increase in heart rate when the supplement is first used. It has a definite benefit for people to whom the world seems too hectic and overwhelming.
Hyaluronic Acid Double Strength 100mg – w/ Proline, Alpha Lipoic Acid & GrapeSeed extract.
April 04, 2007 09:38 AM
Hyaluronic Acid has emerged as one of the most significant anti-aging supplements in the natural products industry. As a mucopolysaccharide that occurs naturally within the human body, the highest concentrations of Hyaluronic Acid are found in the skin, eyes, and articular cartilage. Hyaluronic acid works by absorbing water within the body, which in turn supports the formation of effectiveness of the gel-like matrix that protects healthy cell structures from dehydration and free radical damage. Ongoing studies continue to suggest that it may help support some of the body’s most vital functions.*
Strong, Healthy Joints
At birth and well into our youth, the human body produces ample amounts of Hyaluronic acid. These levels decline, however, based on our physical activity levels, dietary habits, and other hereditary and environmental factors. Hyaluronic acid is a key component of synovial fluid and cartilage, and serves as one of the body’s most vital natural lubricants. Joint structures lack blood vessels, and there for relay on Hyaluronic acid to transport fluids and nutrients. Many structural and articular challenges have been traced back to insufficient Hyaluronic levels.
Wrinkles and Fine Lines
Healthy, wrinkle-free skin requires a constant supply of water. Without enough, dermal cells located deep below the skin’s surface can becomes deprived of the compounds they need, thus leaving the skin dry and dehydrated. Hyaluronic acid attracts and binds large amounts of water at the cellular level to ensure that the skin has everything it needs to remain smooth, elastic, and youthful-looking.
Some published reports suggest that a child’s ability to produce abundant amounts of Hyaluronic acid may explain why they heal so quickly, often without permanent scarring. Because of the many roles it plays within the body’s connective and epidermal tissues, Hyaluronic acid is becoming more and more accepted as a way to help encourage the body’s natural wound-healing processes.
Vision and Eye Health
In addition to cartilage and synovial fluid, the eyes contain some of the body’s highest concentrations of Hyaluronic acid. In fact, the vitreous humor (the Eye’s Core) is made up almost entirely of Hyaluronic acid. This gel-like structure absorbs shock, supports vision, and protects the retina from being damaged. It is believed that many common vision and ocular problems may be a result of poor Hyaluronic acid production during adulthood.*
Each Vcap contains 100mg of Hyaluronic acid, along with Alpha Lipoic Acid, standardized Grape Seed Extract, and pharmaceutical grade L-Proline for support. Compare Now’s 100mg formula to some 50mg formulas that do not include supporting antioxidants for the same price, and the choice is clear!
Supplements good for reducing stress and boosting energy!
March 26, 2007 02:05 PM
More and more Americans are feeling overworked, overtired, and overcome by life’s demands. We just do not have the energy we need to meet our responsibilities to the people we care about. More importantly, we don’t even have the energy to have fun! It seems that a constant feeling of fatigue has become part of the American way of life.
Research has shown that the same processes that cause lack of energy can rob us of sleep, saddle us with excess weight, disrupt our hormonal balance, and create significant amounts of stress in our daily lives. Chronic stress can dramatically contribute to fatigue, sleep disorders, irritability, and anxiety. The research simply confirms what most of us already know – uncomfortable stress can really wear us out mentally and physically! It can take away the satisfaction of a job well done. It can take away our ability to believe in ourselves. And, sadly and maybe most importantly, continual stress can take the fun and joy out of life.
In a separate issue of Ask the Doctor, we discuss the energy and sleeping needs of people suffering from chronic fatigue syndrome and fibromyalgia. In this issue, I discuss the 3-step process I call “Vitality 101.” People do not have to accept pain, insomnia, or fatigue. It’s time for everyone to feel great and have a life they love!
Step 1 – Nutrition
Good overall nutrition is important for everyone! As a foundation product to support energy levels, a powdered drink mix is a pleasant, easy way to ensure that you are taking all of the necessary vitamins, minerals, and amino acids that you need to have great energy all through your day.
The following chart lists the most critical ingredients. You can see that almost all of the vitamins and minerals work together to help improve energy levels and overall health.
In addition to the powdered energy drink mix, it is important that you also take a high potency vitamin B-complex supplement. This should include niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, which are especially important to restore the energy production needs of your body. It is also critical to get enough water, as most Americans are chronically dehydrated.
Step 2 – Rest Your Body
Having trouble sleeping is one of the most troubling symptoms of stress. While the stress is wearing us down and making us tired, it’s also keeping us tense and unable tot relax. The result? That easy drift into sleep becomes harder and harder. And if we are lucky enough to actually get some shut-eye, stress will often wake us up, sometimes several times a night.
This occurs because excess stress suppresses the sleep center in the brain. It is important to break the “stress/insomnia cycle” early, before it results in pain and hormonal and immune dysfunction!
Because good quality sleep is how the body repairs and re-energizes itself, it may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Look for a supplement that has a blend of herbs that promote deep sleep, such as valerian, L-theanine, hops, passionflower,
Step 3 – Manage Excess Stress Levels
In this fast paced world, it is important to learn to manage the stressor in our lives. Glandular extracts, such as raw adrenal extract, can offer natural support to help our bodies deal with the effects of stress and, in turn, can boost your energy levels. Exercise is another stress buster. Using your body physically is important for good health. Find something that is fun for you, however, or you are unlikely to stick with it!
Q. Does stress zap my energy in any other ways besides making me lay awake at night and causing me to be a zombie the next morning?
A. Most people are familiar with the body’s dramatic response to an emergency. The heart pounds, the muscles constrict, and the lungs expand – and while this is happening, we are capable of greater than normal strength and speed. This response is the body’s way of rescuing itself when faced with an emergency. We don’t have to think about it to make it happen. It’s automatic.
The same can be said of a chronic stress response. Whether we’re late for a business meeting because we’re stuck in traffic, or worrying about how we are going to pay for our children’s college tuition, our response to stress happens automatically. The difference between the two is that the body’s response in an emergency starts and resolves itself quickly. The response to being stuck in traffic may not.
The body makes the “stress hormone”, cortisol, to handle the normal stresses of day-to-day living. But in an emergency situation, the adrenal glands, located above the kidneys, secrete increased amounts of this hormone until the emergency passes. Then the body returns to its normal function. Unfortunately, however, chronic stress is more complex. When our body is subjected to increased amounts of the hormone, cortisol, for an extended time, it can lead to a condition known as “adrenal burnout” or “adrenal fatigue.” While it’s true that very large amounts of cortisol can have damaging effects on our hormones, too little cortisol doesn’t allow us to respond to stress properly. It’s really a matter of balance.
Q. How can I control the stress in my life and re-energize?
A. Many people who are under constant stress may have adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.
The good news is that changes in our hormone levels can return to normal when stress is decreased. The key in learning how to deal with daily stress is to allow the body to return to its normal state. I discuss additional techniques for coping with stress in my recent book Three Steps to Happiness! Healing Through Joy (see my website, www. jacobeitelbaum .com, for more information). In addition to stress control, it is important to supplement your adrenals with a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy, which uses the concentrated forms of bovine (cow) or porcine (pig) glands, can improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacked and thus repaired the malfunctioning gland.
If you are one of the unlucky folks with stressed-out adrenal glands, you should see great results from taking raw adrenal supplements. Be sure to buy adrenal extract supplement that contains both whole adrenal and cortex adrenal.
The best adrenal supplement should also contain vitamin C, vitamin B6, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.
Did your grandmother ever tell you to eat your liver so that you didn’t get “tired blood?” Well, it turns out that she was right. Liver extract is another glandular extract that can help improve energy levels.
Liver extract is an excellent source of highly bioavailable nutrients including iron, B vitamins (especially B12), and other minerals. The stamina and energy-enhancing benefits of liver are widely touted. Liver extract has been shown to support healthy function of the liver and increase the energy levels inside our body.
Because heat will destroy the key components in the liver, a high quality liver extract supplement should be cold-processed and encapsulated to enhance speed and absorption of nutrients from liver. A high quality aqueous liver extract supplement should also contain vitamin B12 to support healthy blood iron and oxygen levels to energize.
Q. It will be great to get a good night’s sleep. Are there also any other natural alternatives that could help promote relaxation and increase my energy levels during the day?
A. Yes, there are. Rhodiola rosea is an all-natural herb that has long been used to help relieve stress and increase energy. Rhodiola has also been used to lift our moods, improve sexual satisfaction, and even help in certain nervous system disorders. First used in Siberia and
In clinical trials, the most effective Rhodiola rosea extract was found to contain 3% rosavins and 1% salidroside. While there are many Rhodiola supplements in health food stores, only those containing these specific amounts can provide the best results.
Altered digestion, food intolerances, decreased energy, fatigue, cognitive problems, and sleeplessness create the need for changes in daily living routines. These can include alterations in diet; exercise modifications; alterations in activities of daily living according to one’s energy level; and sleep/rest management. All may require the assistance of a professional clinician, such as a chiropractor, nutrition specialist, physical and/or occupational therapist, mental health professional, or sleep therapist.
Super busy lives demand super strength nutrition. Begin each day with a powdered nutritional supplement after getting at least 8 hours of sleep each night. In addition to the nutritional beverage mix, a vitamin B complex supplement should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients to combat your fatigue. Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Rhodiola rosea, and ginseng can offer additional natural nutritional support in your busy life to boost your energy levels. These nutritional supplements can be used daily and you will feel energized to get through each day’s challenges and opportunities!
The Benefits of Colon Cleanse
December 01, 2006 04:29 PM
There are many substances that can wreak havoc on your body. A healthy body has the natural ability to eliminate toxins that we are exposed to everyday—and the colon is one of the primary organs involved in the body’s detoxification process.
But when this internal detoxification process breaks down, toxins circulate into your bloodstream instead of being eliminated through the colon. This can lead to a range of health challenges. Colon cleansing then becomes one of the most important steps you can take.
The Benefits of Colon Cleanse
Health Plus Colon Cleanse is an excellent source of soluble fiber from psyllium husk. Fiber is essential for intestinal health and keeping the body functioning properly. It takes the digestive tract from being clogged up with waste and toxins and keeps the colon clean. It also helps to support healthy flora in the intestine.
The soluble fiber in Colon Cleanse can also help to support cholesterol levels already in the normal range. Cholesterol attaches itself to fiber and is carried out of the body with solid waste matter. A serving of colon cleanse supplies 5 grams of the 7 grams of soluble fiber necessary per day to have this effect.
Health Plus Colon Cleans is on sale today. Stock up now!
Pycnogenol: Heart, Blood Sugar and Cellular Health
November 03, 2006 12:16 PM
Pycnogenol (pronounced pic-nojen-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France. Pycnogenol® consists of particularly bioactive flavonoid species and its purity is in strict accordance with the United States Pharmacopoeia. Pycnogenol® was initially developed 35 years ago in Europe. During the past years it evolved as one of the most thoroughly researched nutritional supplements, with over 200 studies published in peer-reviewed journals. Seventy of these studies were clinical with in total more than 4,000 patients. Pycnogenol® taken in dosages from 25mg to 300mg is well tolerated and Pycnogenol® was attributed “generally recognized as safe” (GRAS) by the FDA.
Pycnogenol® supports healthy capillaries
The “Career” of Pycnogenol® began in Europe, where it was first used to maintain vein and capillary health. Pycnogenol® has been shown to strengthen blood vessel walls, with 15 clinical trials showing fast relief from ankle and foot discomfort. A recent study with 200 passengers on long-haul flights showed that Pycnogenol® taken before departure and again during the flight supports foot comfort and healthy circulation. Travelers typically comment that with Pycnogenol® it is much easier to put shoes on again upon arrival. Clinicians in Germany discovered that Pycnogenol® also supports healthy capillaries in the eyes. Retinal capillaries may be affected by imbalanced blood sugar levels. In a multi-center field study with 1169 subjects Pycnogenol® supported healthy capillaries in the retina and improved visual acuity to some extent.
Pycnogenol® benefits the cardiovascular system
More detailed investigation of the interaction of Pycnogenol® with blood vessel walls at the University of Florida, Tampa led to an amazing discovery. Pycnogenol® stimulates an enzyme in blood vessel walls that is responsible for generating the most important vascular mediator, known as “nitric oxide” (NO). NO triggers relaxation of the arteries and supports clear blood flow. Hence, NO is the body’s mediator for maintaining healthy blood pressure levels and circulation. NO plays such an important function for cardiovascular health that Dr. Louis Ignarro (UCLA) and his co-workers received the Nobel Prize for this discovery in 1987.
A number of factors, including aging, can interfere with the body’s efficient production of NO. Supplementation with Pycnogenol® for four weeks was shown to restore NO production and improve blood supply to the fingertips of elderly people in a Japanese study. Microscopic evaluation of blood vessel diameter at the root of fingernails showed an increased diameter of capillaries allowing better blood perfusion. Specific sensors applied to the legs showed increased oxygen and decreased carbon dioxide presence. Better blood, nutrient and oxygen supply with Pycnogenol® benefits everybody. Italian researchers were able to show that regular intake of Pycnogenol® helps defy muscle cramps and minor pain in athletes.
The relaxation of arteries has a favorable effect on blood pressure. In two clinical studies Pycnogenol® taken for at least eight weeks was found to significantly support normal blood pressure.
Pycnogenol® stimulated NO generation directly translates into clear blood flow. This was first demonstrated at the University of Arizona, Tucson in smokers. Pycnogenol® dose-dependently, starting at a single dose of 25mg, countered the typical effects of cigarette smoking on the blood. Also, Italian vascular specialists found that Pycnogenol® supported the circulation of individuals on flights between New York and London.
Pycnogenol® supports healthy blood sugar levels
Pycnogenol® can support normal glucose levels when taken as part of a healthy diet and lifestyle plan. A clinical investigation has confirmed the significant glucose-lowering effect of Pycnogenol®. It was noted that Pycnogenol® did not affect insulin levels. Pycnogenol® appears to facilitate previously insulin-resistant cells to uptake sugar from the blood stream by yet unknown mechanisms.
Pycnogenol® limits cellular irritation
Two clinical studies carried out in Germany this year with student volunteers demonstrated that Pycnogenol® has a potent effect in preventing cellular irritation. Pycnogenol® inhibits a molecular “main-switch” in immune cells that triggers the onset of cellular irritation in any part of the body. Moreover, Pycnogenol® was found to inhibit so-called COX enzymes, which are involved with minor pain-sensation related to cellular irritation.
Pycnogenol® sooths menstrual pain
Japanese gynecologists discovered in 1999 that regular supplementation with Pycnogenol® soothes the normal discomfort of menstrual pain, particularly during cramping. Another clinical investigation of 47 women in year 2004 confirmed the effect of Pycnogenol® in addressing menstrual pain. This year a double-blind, placebo-controlled, multi-center field study with 116 women again confirmed these results. Pycnogenol® is not suitable for on-demand relief during menstruation. The studies show that Pycnogenol® reached highest efficacy when taken regularly for months.
Pycnogenol® helps to support respiratory health
challenges to normal respiratory function may result from incidents the immune system perceives as harmful. Pycnogenol® offers valuable help in supporting respiration due to its immune-modulating effect and its ability to limit cellular irritation. A study at the University of Arizona found that Pycnogenol® supports clear breathing and lowers mediators of cellular irritation in the blood stream. More recently, a placebo-controlled clinical study at the University of California, Loma Linda described how Pycnogenol® supported healthy respiration in 60 children aged 6-18 years. Pycnogenol® needs to be taken continuously for prolonged periods of time for maximum benefit to the respiratory system.
Pycnogenol® is investigated in clinical trials all over the world. New findings are posted on the website www.pycnogenol.com.
Frank Schonlau Ph.D. is a biochemist who has spent nine years in medical research at the University Clinic of Munster Germany. His area of expertise covers vascular disorders, inflammation and dermatology. He has published more than 20 studies and review articles in the medical literature. Since entering the dietary field in 1999 he was involved in numerous studies on Pycnogenol® and communication of new health discoveries.
Interview on symptoms of Fibromyalgia and one mans story
August 09, 2006 03:25 PM
Interview with Todd Williams from Source Naturals
Todd: Michael, many of us know someone with fibromyalgia, but many of us don’t know what FM is. Can you help explain the disease?
Michael: Yes. Fibromyalgia (pronounced Fie-bro-my-AL-ja) is a complex chronic pain illness that challenges patients and health care professionals alike. It is estimated that fibromyalgia affects 8 – 10 million women, men, and children in the U.S. alone. Symptoms include: extreme fatigue, sleep abnormalities, cognitive problems, difficulty speaking clearly, memory loss, brain fog, and so on. There’s also irritable bowel syndrome, restless legs, migraine headaches, neurological symptoms, anxiety and environmental sensitivities. Ninety percent of those afflicted with fibromyalgia are women. Ten percent are men. What activates fibromyalgia within a person can be anything from a thyroid condition to an auto accident, or some type of trauma or emotional stress. There is often a compromised immune system, hormonal imbalance, and even a possible enzyme deficiency. Because the stomach and intestines are made up of muscles, fibromyalgia affects the entire digestive tract. The members in my fibromyalgia support group in Santa Monica all have stomach problems. One of the doctors believes that the fibromyalgia I have to battle with daily is a result of a thyroid problem. Thyroid problems run in my family and, not surprisingly, my brother, who lives on the other side of the country has fibromyalgia as well. We correspond and share with each other what does and doesn’t work. My ten-year career as a schoolteacher came to an end due to having fibromyalgia. I lost the energy I needed to work non-stop ten-hour days. I was forced by necessity to go into early retirement. As a result, I had to find a new manageable way to live. So I then went to Los Angeles to pursue a part time acting career. Now, regardless of whether a task is big or small, I just try to do my best, one day at a time.
Todd: Michael, how did you experience the onset of Fibromyalgia?
Michael: although I’ve really had fibromyalgia for fifteen years, I wasn’t actually diagnosed by my doctor until 1996. I was very energetic and athletic while growing up. During my twenties, I first went to University of Arizona in Tucson, and then to Oral Roberts University in Tulsa, Oklahoma, and later to Point Loma University in San Diego, where I received a Master’s Degree in education. I followed that by moving to Florida to teach and to spend some time with my family. During summer breaks from teaching, I would go down to Florida Keys and visit Miami for fun. I had plenty of energy up until I was 28-30 years old, when I noticed a drastic drop in my energy level. At that time, when I would exercise, it was very difficult for my muscles to recover after a workout, even if it was a light workout. By the time I was thirty, the muscles in my feet became unbearably tight. It became very difficult to stand or even walk very far. I had my feet X-rayed, and the reports would say that nothing was wrong. When I was thiry-five, I took some antibiotics to get rid of a cold and I ended up with severe reaction to the antibiotic, erythromycin. My stomach swelled up like a balloon and felt unbearably tight. This was my first experience with IBS (Irritable Bowel Syndrome). I could no longer digest my food. I developed severe food and chemical sensitivities. I could no longer digest vitamin B properly. I would be in excruciating pain for several hours after eating almost anything. I had to leave my teaching position and I ended up being mostly bedridden for two years due to exhaustion and the inability to digest food. During this time I went to twenty doctors. I had colonoscopys, endoscopies, barium x-rays and thyroid tests, but the results were always indicating a normal range. I knew that I was horribly sick but the doctors and the tests repeatedly said that nothing was wrong with me. nevertheless, the doctors did provide more prescription medicines, especially antibiotics. It’s strange that not one of these doctors mentioned or prescribed probiotics in any form for rebuilding the flora in my intestines that was destroyed by the long antibiotic regimen. Eventually I would end up spending a large sum of money and going to 40 more doctors, with each helping just a little. It was a relief when I was finally diagnosed with fibromyalgia, because it helped me narrow in on what was really going on. Which everything falling apart, it was a relief to know it wasn’t a rare foot disease, or a stomach parasite, or AIDS. I wanted to encourage men and women who are finally diagnosed with fibromyalgia to not see it as a death notice, but rather a step in recovery. In 2002, I tried something new. I went online and submitted my medical history to Dr. Teitelbaum’s Diagnosis Program, which you can find at www.vitality101.com. His incredible program spat out about 200 pages of very insightful information on what my body was deficient in. I began taking some of his recommended supplements and began to see some definite results. In spite of my poor track record with medical tests, he also recommended thyroid testing for fibromyalgia suffers, even though it is well known that thyroid tests are frequently wrong. Dr. Teitelbaum believes that many people who have fibromyalgia were actually having a thyroid problem, even though their thyroid tests come out in the normal range. I’ve had numerous thyroid tests over the years, and they’ve all been normal. I trekked back to my doctor and pleaded with him, even mentioning that there was a history of thyroid problems in my family. At first, he refused, simply because the tests said normal. I think doctors, fearing litigation, are reluctant to try a treatment path unsupported by test results. When you think about it, test ranges are really averages. What happens if your physiology falls outside the normal average? The tragic answer is: you can fall through the cracks! Finally, after much debate and arguing, I was able to get my doctor to provide a prescription for a small dosage of thyroid medicine. I began taking it immediately after two days I began to notice that the tight muscles in my stomach and legs began to loosen up. This seemed miraculous. Unfortunately, I also had some negative side effects from the medicine, so I stopped taking it. Nevertheless, I was amazed at how my body responded to such a small does of thyroid medicine. I think Dr. Teitelbaum is onto something. If you are fortunate enough to have an open minded doctor, perhaps that avenue is worth exploring. In Dr. Teitelbaum’s book, From Fatigue to Fantastic, he also advocates supplements for helping people with Fibromyalgia and chronic fatigue. I can verify that supplements have absolutely becomes part of my program and helped with restoring my systems to their natural balance. Some supplements that really helped me are: NADH, Glutathione, L-Carnitine, Acetyl L-Carnitine, revitalizing sleep formula, daily infusion powder and calcium D-Glucarate. Please feel free to check out the full list of supplements on my website. If you are fatigued, you should really read Dr. Teitelbaum’s book. To fibromyalgia sufferers, I highly recommend checking this list, visiting these doctors’ web pages, and trying their protocols. Thanks to these doctors and various regimens, including supplements, my health is much, much better. Most people would have never guessed I went through such an ordeal. I still have to pace myself, and not push the limits. Staying healthy and maintaining my energy is a priority, so I’ve learned not to over-extend myself. I’ve learned to say no to some projects and activities and not feel guilty about it.
Todd: Wow! That’s a lot to go through. Facing such huge obstacles, how did you keep your ship facing forward?
Michael: Well, living and healing are spiritual events. I am fortunate to have a degree in theology and I have a strong daily spiritual practice, which has helped me to survive and thrive with complications of fibromyalgia. That’s not to say there haven’t been some very dark days, but faith in God and the support of my spiritual network, including my wonderful family and friends have made all the difference. After arriving at LA, I had moved into a little apartment across the street from Warner brothers. My roommate and I had decided to start a little bible study. We invited our neighbors and we prayed for many things including for my health to improve. One of our requests was for a door to open at Warner Brothers. Within a short time, our Bible Study group grew and our home couldn’t contain all the people. A year later, the doors opened for me at Warner Brothers, and I was working on the West Wing.
Todd: that’s Great! Can we tell the folks about your new show?
Michael: My web page has a new category called, “Nutrition Show”, which will provide all the details.
Todd: Thanks Mike! For more about Mike and fibromyalgia, please visit his website at: www.captainhastings.com
Doctor’s Corner - Relora: Minimizes Stress-Induced Eating
August 09, 2006 01:56 PM
Relora is a proprietary all-natural botanical product developed by Next Pharmaceuticals, Inc. it contains ingredients extracted from two plant species that have been used in traditional Chinese herbalism for over 1500 years. These are patented extract from Magnolia officinalis (US Patent No: US 6,582,735) and a patent-pending extract from Phellodendron amurense.
Relora helps relieve stress, anxiety and minimize stress-induced eating, which in turn may help to produce weight loss when used as part of a healthy diet and exercise plan. The research and development of Relora involved sophisticated testing and screening for ingredients that have anti-anxiety properties, but no daytime sedative effects. Initially, investigators tested the Magnoliaceae plant family as a lead source of new anti-anxiety products. Scientists first focused on two phytochemicals on constituents in the plant that have “bio-activity” (work positively on the body)—magnolol and honokiol. Through a series of studies, it became clear that Relora was a safe and effective formulation.
Relora works with the body’s natural chemistry to maintain normal levels of stress hormones. These hormones not only affect emotional well-being, but can also have a major impact on appetite and how the body stores and metabolizes fat. By working to re-establish a stable balance of these hormones, relora can help break the stress/weight cycle and restore optimum health to the mind and body.
In addition to normalizing stress hormones, Relora has been shown to control anxiety and the symptoms associated with it: irritability, emotional ups and downs, restlessness, tense muscles, poor sleep, fatigue and difficulty concentrating. Daytime sedation often occurs with products that induce relaxation. Not with Relora! This breakthrough botanical provides all the anti-anxiety benefits without inducing daytime sedation. In central nervous system receptor binding assays, the plant extracts in Relora bind to several important targets associated with anxiety. Also if interested, the bark of magnolia officinalis has been used in traditional Chinese herbalism for centuries for stress induced muscular tension.
Relora, Stress and Weight Loss
Stress is reported to play a significant role in a wide variety of health conditions. Recent work with the National Institutes of Health (NIH) and other major research centers has demonstrated that stress is a significant contributor to immune dysfunction, cardiovascular challenges, other age-related imbalances, and excess body fat. This type of fat is related to stress-induced hormone imbalances, especially imbalances of the hormones cortisol and DHEA. Until now, the only course of action for losing this fat has been stress reduction with exercise and diet, and anyone who has attempted diet and exercise alone often encounters a long, troublesome road. Relora may help the body normalize cortisol and DHEA levels in stressed individuals while inducing relaxation, and act as an aid in controlling weight and stress-related eating.
The increase in cortisol levels signals the brain that the body is in stress, causing food cravings, especially for high-fat, high-sugar foods. These foods, in turn, cause additional stress, thereby fueling the stress-cortisol cycle. Eventually, more fat is stored than the body needs unless sufficient exercise is in place to compensate, or the stress is reduced.
The ingredients in Relora are key supplements that help the adrenal glands to “come back to life” by reducing the excessive stress hormone response in the body and reducing carbohydrate craving behavior.
Results from Human Trials with Relora
Relora was tested at the Living Longer Institute in Cincinnati, OH and found to be safe, effective, rapid acting, non-sedating dietary supplement that helps control occasional mild anxiety. Three hundred forty five female subjects were administered Relora for 2 weeks. The dosage was 200mg of Relora three times daily. Eighty nine percent of the subjects reported that Relora helped them relax, while 78% found Relora to help prevent stress-related eating.
A second trial was undertaken at the Living Longer Institute to measure cortisol and DHEA levels in patients with mild to moderate stress. Elevated cortisol levels and depressed DHEA levels are associated with chronic stress. A two week regimen of Relora produced a significant increase in salivary DHEA (227%) and a significant decrease in morning salivary cortisol levels (37%). These findings support Relora’s ability to relieve stress and its potential role in weight control and stress-related eating behavior.
A third study was completed in late 2002 that evaluated Relora on its ability to improve snacking habits in people who snack on sweets or eat salty snacks when they are under excessive stress. Forty nine subjects were evaluated and it was found that Relora cur sweet snacking in the sweet cravers by 75%! It cut snacking on salty snacks by 50%. Seventy three percent of all individuals in the study reported feeling less stressed while taking Relora.
A double-blind placebo-controlled study was completed in January, 2004. forty premenopausal women were evaluated for stress, anxiety, food intake and weight management. Relora significantly reduced anxiety and prevented weight gain. A significant weight gain occurred in the placebo group while either now weight gain or weight loss occurred in the Relora group.
Suggested Use and Safety
Relora is designed for adults. The suggested daily dose is 1 capsule (250mg) 2 – 3 times per day. Relora is not recommended for persons under the age of 18. if you are pregnant, nursing or taking a prescription drug, consult a health practitioner prior to use.
Dr. James B. LaValle, R.Ph., N.M.D., C.C.N. is a licensed pharmacist (University of Cincinnati College of Pharmacy), certified clinical nutritionist (International & American Associations of Clinical Nutritionists), and doctor of naturopathic medicine (Central States College of Health Sciences, IAACN), with more than 18 years clinical practice experience in the field of natural therapeutics and functional medicine. Dr. LaValle is in clinical practice at the Living Longer Institute, a comprehensive wellness, prevention, and early detection program he co-founded. He sits on various scientific advisory boards within the dietary supplement industry. LaValle is also an adjunct professor in the college of pharmacy at The University of Cincinnati and serves as a preceptor in the Department of family Medicine, University of Cincinnati College of Medicine.
July 06, 2006 02:18 PM
Restoring optimum liver function is one of the most important and vital actions people can take to improve their health. The liver is the largest organ in the body and carries a greater workload than all other organs. The liver works full time both converting the food that one eats into substances vital for life and neutralizing and destroying toxic matter.
If your customers have tried many ways to improve their health and energy level and nothing has seemed to adequately help, it is very possible that an overworked liver underlies their difficulties.
The natural course of life can cause the liver to get stressed, overworked and exhausted. Toxic chemicals, preservatives, poor diet, cigarettes, alcohol and prescription drugs all cause the liver to deteriorate, drain its energy and make it hard or even impossible for it to perform its functions. This can create a “State of energy” within the body that debilitates and damages other organs, leading to numerous chronic conditions.
As the detoxifying center of the body, the liver has a daily workload of neutralizing toxins such as pesticides, caffeine, alcohol, medications, chemicals, preservatives, auto exhaust and cigarettes. The liver helps remove these materials by breaking them down, enabling us to survive the enormous toxic challenges in today’s environment.
Symptoms of a congested liver
Ultimately, one’s health can only be as good as the health of his liver. A poorly functioning liver will affect all other organs. Weight gain and depression are two menifestations of a congested, overworked liver. Other common symptoms and conditions include being on edge (easily stressed), emotional roller coaster, elevated cholesterol, skin conditions, skin irritation, sleep difficulties, fat indigestion, kidney damage, heart damage, brain damage, hypothyroidism, chronic fatigue, poor memory, PMS, mental fog, blood sugar disorders, allergies and obesity.
When the liver gets congested and toxic, it will remain that way and get worse until it is detoxified and rejuvenated.
Liver Rejuvenator is a breakthrough product the most powerful liver formula available today. Made from a unique combination of the finest Chinese herbs and the best of Western herbs, Liver Rejuvenator detoxifies as well as rebuilds the liver.
No other formula can renew liver health as effectively, rapidly and gently as Liver Rejuvenator. This product sets a new standard for efficiency and results. The liver has everything to do with a person’s energy level. If your customers want high energy, great stamina and overall good health, tell them to be sure to keep their liver in excellent shape. Not detoxifying the liver is like never changing the oil filter in one’s car!
A healthy liver can mean much more energy, greater mental clarity, better mood, improved health, protection against countless ailments, and finding relief for conditions that may have been plaguing your customers for years.
Here are just some of the benefits Liver Rejuvenator users report: reduced stress, higher energy, mood elevation, feeling calmer and more relaxed, reduced or no headaches, less muscle or joint pain, eye or vision improvement, relief from skin irritation, enhanced mental clarity, less congested (sinus and chest), improved overall health.
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
May 30, 2006 02:36 PM
Ambassador to Health Profile
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
Congressman Sam Farr, a fifth-generation Californian, represents the state’s beautiful central coast. His district encompasses the length of the big Sur coastline in Monterey County, the Monterey Bay National Marine Sanctuary, the Salinas Valley “Salad bowl,” the redwoods, mountains and beaches of Santa Cruz County, and the majestic rural landscape of San Benito County. The health and wealth of this region has been strengthened by Rep. Farr’s focus on the environment, education and the economy. Rep. Farr was raised in Carmel, California and graduated from Willamette University with a BS in biology. He later attended the Monterey Institute of International Studies and the University of Santa Clara. He is fluent in Spanish. As a tough advocate for the health food industry, he has lobbied for strict federal organic standards.
Todd: Congressman Farr, thank you for taking the time to speak with us! Id also like to thank you for all the great things you’ve done for our community, form funding marine sanctuaries and authoring the Ocean’s Act to expanding Pinnacles national Monument. The League of Conservation Voters and others have recognized you as an “Environmental Hero”. And, you’ve worked hard to support the economic vitality of central coast’s $3 billion agriculture industry which includes a substantial organic segment. Our backyard here is also the home of a robust group of nutritional supplement manufacturers. An estimated 187 million Americans are currently taking dietary supplements as part of their daily healthy diet. In California, we’ve got 792 natural product manufacturers and distributors. Where do you stand on the state of our industry?
Congressman Farr: Well, thank you for the introduction and for asking to talk to me about nutritional supplement issues. I am very supportive of this industry and include myself in the 187 million Americans taking dietary supplements. I think supplements offer many safe and viable tools to maintain your health. The continued growth of this industry is an indication of both consumer confidence in the products and the products’ ability to fill the gaps where conventional medical care falls short.
Todd: It is estimated that by 2030, more than 70 million Americans will be over the age of 65 and the cost of health care could reach $16 Trillion per year. A recent study by the Lewin Group showed that by taking certain dietary supplements, seniors can lead healthier, more productive, independent lives while saving billions in reduced hospitalizations and physician services. Do you share our view that a Wellness Revolution is needed to counter the dilemma of an aging population versus shrinking health care support in the future?
Congressman Farr: Our health care system is definitely facing a challenge, especially as the Baby Boomers hit their 60’s and Americans are living longer than ever before. As a Baby Boomer myself, I am well aware of America’s aging population and the impact that will likely have not only on our social institutions but also our fiscal well-being. I agree that dietary supplements do play and will play an even larger role in the future as more seniors look for a way to augment their diets in order to stay healthy and active longer than past generations.
Todd: Our industry is regulated by DSHEA (the Dietary Supplement Health and Education Act), which was passed unanimously by Congress in 1994 to create a reasonable regulatory framework for access to, information about, dietary supplements. But many say that the FDA and DSHEA weren’t adequately funded to do the job as tasked. “Supplements are unregulated” is a false argument we sometimes hear. To ensure that the FDA is able to carry out the law as Congress intended, Representatives Dan Burton (R-Ind.) and Frank Pallone (D-N.J.) introduced H.R. 2485, the DSHEA Full Implementation and Enforcement Act of 2005. Did you support this bill and where does it stand today?
Congressman Farr: I think the DSHEA is a critical law and was proud to support it when Congress considered it in 1993 and 1994. I would certainly support H.R. 2485 if it came up for a vote in Congress. Unfortunately this bill has not moved since it was first introduced and referred to the Subcommittee on health in the house energy and commerce committee. Since this is an election year we have a tight schedule with only about 60 legislative days scheduled before we adjourn. That means it’s likely Congress will only finalize bills such as the appropriation bills that fund government before adjournment.
Todd: Our business climate has included some valid and rigorous challenges to improve our industry, from good manufacturing practices (GMP), to allergy labeling, to implications of Prop-65 in California. It’s disconcerting that a new bill, H.R. 3156 The Dietary Supplement Access and Awareness Act would try to capitalize on misconceptions about the industry. In an era of declining health care and declining insurance coverage, this bill would regulate supplements as prescription drugs. Among other things, it would also require adverse event reports to be turned over to the FDA, even though other foods, including those with identical ingredients, do not have the same requirements. This has the potential to be the next Prop-65-like Lawsuit mill. The result of H.R. 3156 would be chilling. It will knock smaller producers out of the market. It will result in higher prices for all supplements. It will decrease the availability of health-giving supplements to the public. What’s your feeling on this?
Congressman Farr: I am similarly concerned about H.R. 3156 and would oppose it if it came up for a vote in Congress. Like H.R. 2485, this legislation has been referred to a subcommittee on Health in the House Energy and Commerce Committee without any further action. The supplement industry has worked in good faith with the FDA since passage of DSHEA and H.R. 3156 would re-invent a wheel that isn’t needed. Instead, adequate funding as proposed in H.R. 2485 would provide ample oversight for the industry.
Todd: According to a recent study, 72% of the general population believe the government should fund more research on health benefits of nutritional supplements. Do you agreen and what can be done to meet this need?
Congressman Farr: I definitely agree that the federal government should play a bigger role in support of research regarding the health benefits of nutritional supplements. As a member of the House Appropriation Committee, I sit on the subcommittee that has jurisdiction over the FDA’s budget and I know the tight fiscal restraints the agency is under. I’ve worked with my colleagues to provide adequate funding, but it’s an uphill battle especially when we’re in a “robbing Peter to pay Paul” kind of situation. I recommend that people within the industry organize and use your consumer base to actively lobby Congress for additional funds. I’m fond of reminding people that the squeaky wheel gets grease – so let every Congress member and Senator know how much this issue matters to you.
Todd: When there is overwhelming scientific evidence that nutritional supplements provides relief for a disease condition, it currently takes a lawsuit to get the FDA to relent and allow the claim. Even then, the FDA strictly limits the claim and requires a disclaimer that does more harm than good in communicating this important information to the public. There is a new bill, H.R. 4282, The Health Freedom Protection Act that would end FDA and FTC censorship of health information. As an example, the 50% of all adult males who suffer from an enlarged prostate could receive relief from that condition by consuming a simple and safe ingredient, saw palmetto derived from the fruit of the dwarf American palm tree. The FDA censors that information. The public deserves a better opportunity to be informed about omega-3 EFA and heart disease, folic acid and birth defects, phosphatidylserine and cognitive impairment. Do you agree and do you support this bill?
Congressman Farr: I agree the public needs to access to the best information possible so they can make well informed choices about their health. I likely would support H.R. 4282 if it came up for a vote in Congress. Unfortunately this bill is in a similar situation as other we’ve mentioned in this interview – and again because of the tight schedule of an election year, it’s unlikely action will happen this year.
Todd: According to the barometer study, 85% of the US population is currently using some type of dietary supplement. Do you? Looking at your busy schedule from co-chairing the House Oceans Caucus to your seat on the Travel and Tourism Caucus, you are one busy congressman! Are you popping nutritional supplements please tell us!
Congressman Farr: I do take some nutritional supplements, though they vary and since Ginkgo Biloba isn’t among them I cant remember their names off-hand! One product I do use faithfully is Airborne to help me combat germs and colds that I might get from sitting on an airplane. But, like many Americans my life is over-scheduled and combined with the amount of air-travel I do, I find nutritional supplements helpful as I try to stay healthy despite my hectic lifestyle.
Todd: Thank you Congressman Farr! Live long and prosper!
DSEA Release of Health/Cost Impact Study Conducted by the Lewin Group, Initial Results, Wash DC; Nov. 2, 2005
NNFA database. Adam.F on 3-15-06.
DSEA Nutritional Supplement Barometer Study, 2005 Report, Prepared by the Natural Marketing Institute (NMI).
Todd Williams; Source Naturals Marketing Programs Manager.
At Last some good news concerning breast health!
February 23, 2006 03:33 PM
At last, some good news concerning breast health!
Brevail is for women interested in maintaining optimal breast health.
Perhaps you, like many woman, are concerned with the important issue of breast health. Annual mammograms, monthly self breast exams, escalating national statistics, or perhaps an unfortunate occurence in a loved one has raised awareness and concern in many of us.
There is now reason for Optimism
Brevail is the first all-natural product to address the maintenance of orderly cellular division in the preservation of healthy breast tissue.
Research suggests that our bodies use natural plant lignans, now sparse in the modern diet, to sarely and gently buffer and balance potentially adverse effects of excess or toxic estrogens, established as the most well-known cause of certain breast problems.
Estrogen left unchecked may result in rapid multiplication of breast cells, as well as inability for cells to repair potential mutations between cellular divisions.
Body and Nature is balance
Brevail was university researched and developed to increase lignan concentrations in the body to levels found in women who collectively demonstrate an extraordinary history of breast health.
After only 48 hours of Brevail supplementation, women participating in a university based, oral pharmacokinetics study achieved lignan concentrations in plasma and urine equivalent to a reference group of women with a well-established history of extraordinary breast health.
The results is a gentle return to balance between body and nature, just as nature intended.
In addition to the primary purpose of optimal breast health, many women have reported secondary benefits of brevail related to hormonal balance including improvements in pre and peri-menopausal, menopausal and post-menopausal discomforts. Further, many women have reported a greater sense of well-being associated to a reduction of stress and apprehension, and for taking a positive step toward a healthy future.
Brevail has good news for you, a “window” of opportunity.
The good news is a revolutionary new approach to breast health. Though a new approach, managing your “Estrogen window” is time honored, true, and scientifically established.
Your lifetime exposure to estrogen is the most well-known risk factor for breast related health challenges. Your cumulative lifetime exposure to estrogens is referred to as your “Estrogen window.” Influences that increase and extend exposure to estrogen are said to “open” the window. Those that reduce or shorten exposure are said to “Close “ it. The wider and longer the window is left open, the greater your risk for breast related complications.
Managing your estrogen window empowers you to choose a healthy future.
Brevail is the first all-natural product designed to address the estrogen window by gently displacing excess or toxic estrogens. Adequate rest, exercise, a plant-based diet, and avoidance of alcohol are also ways to which you can consciously choose to manage your estrogen window toward a healthy future.
Make a decision for health, life, and vitality!
Proactive Breast Health is a monumental shift in thinking and action, away for passive resignation and toward proactive empowerment. The difference between fate and destiny is that you can plan your destiny in advance. Make a commintment to Brevail, and make a commitment to health, life, and vitality today.
Brevail donates a percentage of all proceeds to the Breast Cancer Prevention Foundation, established to fund scientific and clinical research into breast cancer prevention, as well as to educate the public and medical community on proactive and preventative breast health measures, and for the purpose of outreach and support for women with breast cancer.
Brevail, winner of two consecutive research grants
Brevail was awarded an unprecedented two consecutive research grants from the Washington Technology Center, University of Washington, in the course of the 6-year span in which it was developed. Lignan Based strategies for Cancer Prevention was the topic and title of the grants.
Instant Energy B-12 2000mcg per serving 75 packets/Box
February 16, 2006 03:46 PM
Of all the vitamins, minerals, herbs and specialized dietary supplements at the disposal of the health-conscious public, not a single one can mirror the biological complexity of Vitamin B-12. It is involved in thousands upon thousands of chemical reactions throughout the body, and its presence has a direct influence on energy, red blood cell production, metabolism, central nervous system function, cardiovascular health, cognitive function, emotion, DNA repair and digestion, just to scratch the surface.*
Our researchers and product formulators had one goal in mind – to develop a vitamin B-12 formula that was superior to anything to precede it – a potent, fast-acting B-12 complex capable of expediting delivery while maximizing uptake. After months of research and development, this was accomplished by uniting cyanocobalamin (the primary form of B-12) with the vitamin’s two co-enzyme forms (methylcobalamin and dibencozide) in perfect balance. But we didn’t stop there. To further enhance the activity of this one-of-a-kind formula, we merged the three with a group of proven synergists that includes Chromium Picolinate, Creatine Monohydrate, and a optimally balanced arrangement of 6 additional B vitamins.
NOW® Instant Energy B-12 makes it simple to get the B-12 they need to function at their absolute best. NOW’s unique collaboration of all three B-12 forms goes to work quickly to effectively boost energy, support cognitive health, promote normal homocysteine conversion and support healthy red blood cell production. Our convenient packets can be taken throughout the day, and are perfect for the office, the car or when traveling.*
Serving Size 1 Packet
Nutritional Supplements Could Save U.S. $6.5 Billion.
January 07, 2006 12:26 PM
Health Care Crisis Bankrupting U.S. Budget
Nutritional Supplements Could Save U.S. $6.5 Billion.
You probably never heard about it on the radio, nor saw its actions reported on CNN. Others can’t guess what its acronym stands for. The United States Government Accountability Office (GAO) is an investigative arm of Congress examining the receipt and payment of public funds. This government office exists for the sole purpose of communicating to Congress those facts and figures which we, as a society, can’t afford to overlook.
And they are saying that the healthcare system is going to bankrupt us. The agency recently issued a special report called 21st Century challenges, which concludes that current U.S. fiscal policies are unsustainable and, unless radical changes are initiated relatively soon, will “result in large, escalating, and persistent deficits.
The Money Pit
According to the GAO report, the United States spends more than 15% of our gross domestic product on health care, and that figures growing fast. We spend a larger percentage than is spent by any other industrialized country. What’s even more suprising is how little we get for the money. An estimated 45million Americans are uninsured. The United States continues to compare abysmally to the other industrialized nations in critical areas like infant mortality, life expectancy, and premature and preventable deaths.
Medicare and Medicaid together devour 20% of the federal budget. With the baby boomers—individuals born between the end of WWII 1960—hitting retirement age this year, those figures will only grow larger with each passing year. Unless, as the GAO report says, something is done quickly.
A report released just weeks ago by the Dietary Supplement Education Alliance (DSEA) demonstrates that the government can save at least 6.5 billion in health care cost reductions if nutritional supplements are integerated into the healthcare system.
The Lewin Group, a market research firm, developed a report, entitled: Increasing Quality of Life While Minimizing Costs. It focused in on just two supplements, both of which concern reduction in disease prevention for people over age 65. Omega-3 oil, popular for its reduction in coronary heart disease, is projected to save 3.1 billion dollars. Lutein and Zeaxanthin, which supports healthy vision, will save 2.5 billion dollars if this supplement is added to health care plans, according to the study. Savings would come from reduced hospitalizations and doctor’s fees, as well as reduced nursing home use for those who in good health, could remain independent rather than needing to transfer to live-in care facilities.
Early last month, a bipartisan caucus on dietary supplements kicked off. It will be co-chaired by Rep. Chris Cannon (R-Utah), and Rep. Fran Pallone (D-N.J.), and its goal will be to examine the manner in which nutritional supplements may become a component of healthcare reform, such as part of an individual flexible Spending Account or health Saving account. As the GAO report indicates, the government interest is reaching critical mass and nutritional supplements are on the verge of entering a new era. As Congressman Cannon said during a November 2nd press conference, government needs to develop a sound policy supporting nutritional supplements “As more and more Americans start taking responsibility for their own health.”
Sources/Links for Further Reading:
Visit the website of the United States Government Accountability Office. //www.gao.gov/
House Government Reform Subcommittee on Human Rights Wellness. //reform.house.gov/
For more information about the Lewin Group’s Health Impact Study, please visit: //www.supplementinfo.org/
GliSODin Anti-Aging and Antioxidant Protection
December 19, 2005 08:47 AM
GliSODin Anti-Aging and Antioxidant Protection
In the time it takes you to finish reading this article, you, your body and your cells will have aged. Some, more than others. Nevertheless, every second that ticks away should serve as a reminder that our time here is temporary. How much time we actually end up with depends on many things. Diet. Lifestyle. Environment. Superoxide Dismutase? I’ll explain. What some of the healthiest individuals fail to realize is that our bodies age from the inside out. Aging is not the result of passing time, but rather the result of what we’re exposed to environmentally, physically and chemically. It is the integrity of our cells, not our clocks, that determine how smooth the aging process fares.
Each day, we’re subjected to millions of elements that affect us in ways seldom seen, felt or noticed. From the moment we’re born, we rely on our cells to work around the clock - producing energy, fighting infections and sustaining life. These same cells eventually determine the rate at which we show (or hide) our age.
Taking into consideration that our planet has no shortage of toxins & germs, the need to safeguard our cells becomes very real. Constant exposure to exhaust, secondhand smoke, heavy metals, lead, fluoride and uncountable other noxious compounds should ideally provide us with nothing more than a routine immune system workout. Unfortunately, over long periods they hinder our “resistance” abilities and become stepping stones to accelerated aging.
Antioxidants. We’ve all heard the term before, and may even have a general understanding of their role. But to better grasp just how vital they are, it helps to know what’s happening at the cellular level. Free radicals are unstable molecular thieves that often lack electrons. To compensate, they rob healthy cells - a process better known as oxidation. Antioxidants work with the immune system to prevent oxidation, and clean up the mess it leaves behind. Hence, the name.
There are two types. Exogenous antioxidants are derived from our diet and include vitamins A, E, and C along with others such as alpha lipoic acid, selenium, CoQ10, grape seed, pycnogenol and zinc. To date, we’ve been limited to exogenous antioxidants as a way to increase the rate at which our body wards off oxidation. They are not, however, our first line of defense. At birth, each and every one of us is equipped with three primary endogenous enzymatic antioxidants; SOD (Superoxide Dismutase), Glutathione Peroxidase (GPx) and Catalase.
While both types of antioxidants are beneficial, we’ve become reliant on those from the diet to compensate for our inability to boost the effectiveness of our 3 primary antioxidants. For years, researchers have been examining ways to enhance the activity of our built-in bodyguards. One in particular, Superoxide Dismutase (SOD) has been of foremost interest. SOD targets what many researchers regard as one of our greatest health threats and aging accelerators - Superoxide radicals. These highly reactive, merciless molecules incite enormous amounts of oxidative stress and are capable of wreaking havoc on healthy cells. When cells are left unprotected by SOD, the results can be disastrous - respiratory problems, premature aging, memory loss, cardiovascular challenges, vision failure and joint structure damage, among others.
Until now, we’ve been at the mercy of our natural SOD reserves to fight superoxides. Researchers have been working feverishly to produce an effective oral SOD supplement, but have continually encountered a frustrating hurdle - exposure to gastric acid denatures SOD, rendering it useless. As a result, the only effective way to supplement SOD was through injections. These, however, only yielded short-term spikes. And then something remarkable happened that changed everything. Nutrition scientists in France determined that by combining Cucumus melo (a melon high in SOD) with a wheat gliadin stabilizer, it would be possible to prevent SOD from deteriorating in the digestive tract, while preserving it in the blood for extended periods. Not only is this the answer to a puzzle that has plagued researchers, it’s a breakthrough that will impact the life of anyone seeking longevity and vitality.
As the first proven oral SOD supplement ever introduced to the public, GliSODin® has taken antioxidant protection, immune support and antiaging science to an entirely new level. The primary function of GliSODin® is to scour the body for superoxide radicals and reduce them to less reactive ions that can be swept away; a process known as dismutation. In addition, GliSODin® reduces the oxidation vulnerability of healthy cells, protects mitochondrial activity and safeguards DNA structure.
What’s most remarkable is that GliSODin® has actually been shown to stimulate the body’s own natural production of all three enzymatic antioxidants, including SOD. For the first time in history, we will have the ability to enhance the effectiveness of our body’s primary defense mechanism.
New GliSODin® from NOW® represents the ultimate in antioxidant protection. By increasing one’s level of SOD while stimulating the natural production of Glutathione Peroxidase and Catalase, GliSODin® delivers antioxidant protection unlike any previously released dietary supplement. Remember, the aging process begins at a level that we simply can not see, the cellular level. Shielding your cells from superoxide damage is one of the smartest steps you can take against aging before your due time. GliSODin® has made this a reality.
AHCC® Fact Sheet - from Now Foods.
December 08, 2005 10:20 AM
AHCC® Fact SheetNeil E. Levin, CCN, DANLA 6/30/05
LIKELY USERS: People needing increased activity of their Natural Killer cells; People seeking improved immune system response; People with a need for tissue repair; People with oxidative challenges; People seeking to increase liver function People defying aging or with a need to improve cellular integrity.
KEY INGREDIENTS: AHCC® (Active Hexose Correlated Compound)
MAIN PRODUCT FEATURES: AHCC® is a proprietary extract produced from specially cultivated and hybridized mushrooms. According to extensive research in humans, as well as numerous non-clinical studies, AHCC®supports immune system function through its effects on macrophages and NK (Natural Killer) Cells. NK cells and the intercellular mediators they produce are critical for the maintenance of healthy cell cycle function. AHCCR® has also been shown possess antioxidant properties, and supports healthy liver function.
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: AHCC® (Active Hexose Correlated Compound) is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product.
AHCC® is a rich source of polysaccharides such as beta glucan 1,3 and activated hemicellulose produced by enzymatic modification of organic medicinal mushrooms, including shiitake. It also has been shown to support normal levels of macrophages and cytokines, further strengthening the immune system.
This formula is suitable for vegetarians and is offered in Vcaps.
SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, take 2 Vcaps® 3 times daily, preferably on an empty stomach.
COMPLEMENTARY PRODUCTS: Antioxidants, Astragalus, Colostrum, Dr. Verghese Liver Formula, Immune Renew, Indole-3-Carbinol (I3C), Inositol Hexaphosphate (IP-6),
PRODUCT SPECIFIC: None
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems. Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.
DISCLAIMER: Information given here may vary from what is shown on the product label because this represents my own professional knowledge and understanding of the science underlying the formula and ingredients. The information in this review should not be used as diagnosis, prescription or as a specific product claim.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G. (2003) Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infectin in mice in the hindlimb-unloading model of spaceflight conditions. J Appl Physiol 95:491-496.
Burikhanov RB, Wakame K, Igarashi Y, Wang S, Matsuzaki S (2000) Suppressive Effect of Active Hexose Correlated Compound (AHCC®) on Thymic Apoptosis Induced by Dexamethasone in the Rat. Endocrine Regulations 34:181-188. Matsui Y, et al. (2002) Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study. J Hepatol. 2002 Jul;37(1):78-86. PMID: 12076865 Matsushita K, et al. (1998) Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anti-Cancer Drugs 9:343-350. Sun B, Wakame K, Mukoda T, Toyoshima A. Kanazawa T, Kosuna K (1997) Preventive Effects of AHCC® on Carbon Tetrachloride Induced Liver Injury in Mice. Nat Med 51(4):310-315.
Ye SF, Ichimura K, Wakame K, Ohe M. Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress. Life Sci. 2003 Dec 19;74(5):593-602. PMID: 14623030 Ye SF, Wakame K, Ichura K, Matsuzaki S (2004) Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat. Endocr Regul 38(1):7-13.
TMG Fact Sheet
December 07, 2005 02:13 PM
TMG Fact SheetNeil E. Levin, CCN, DANLA 03/07/05
LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.
MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.
TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.
Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.
ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.
TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.
DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.
SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.
COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.
People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.
This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
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Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.
Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.
Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.
Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.
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Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.
Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361
Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203
Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266
Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].
van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.
Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.
Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.
Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499
Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].
Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.
Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.
Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329
Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277
Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.
Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887
Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612
Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.
McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907
Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.
Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439
Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].
Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644
Autism & Seizures:
Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.
Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.
Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.
Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.
Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082
Preventing Chronic Health Problems with AHCC
October 26, 2005 05:57 PM
Preventing Chronic Health Problems with AHCC
In a country supposedly as healthy as ours, an estimated 175 million people suffer from one form of chronic imbalance or another. This can take the form of obesity, which is the second leading cause of preventable death in the United States, second only to cigarette smoking; challenges to heart health, blood pressure, blood glucose levels, joint and cell health ,to name just a few.
In fact ,treating chronic health problems is what modern medicine has become .Sure, there are still many acute illnesses treated by modern medicine; but for the most part, we are fortunate enough to have long life spans and the health issues that go along with it. Therefore it is important to make sure that out immune systems are up to the task. That is where AHCC should become part of our daily lives.
AHCC is an nutritional supplement that was developed and is manufactured solely in Japan under strict practices. It is a hybridized extract of medicinal mushrooms where the active ingredient is an oligosaccharide made from the mycelia of several species of mushrooms, grown in rice bran.
AHCC and Cell Senescence
Every few years, a new buzz word comes along in medical circles. The latest one to be used both in a positive and negative fashion is senescence. For example, if an unhealthy cell can be artificially made to senesce, or grow old, then it will die sooner. If senescence of healthy cells can be delayed, that is an amazing achievement.
AHCC is the first nutritional supplement that shows principles of being able to promote certain cells in the immune system that keep us young and healthy, thus delaying immunosenesnscence.
AHCC and the Immune System
In order to get a full appreciation of how important taking AHCC on a daily bases is, one needs to understand the intimate role the immune system plays in our daily lives. It is responsible for riding our bodies of the unhealthy cells that are produced every day. The immune system protects us from the polluted air we breathe, the chemicaalized foods we eat, and most importantly, from the stress we bring upon ourselves just by the very nature of the way we live our lives. Our bodies were made for flight or fight capability; but never in history have we been in that mode on a daily basis. Our immune systems are under constant assault and it is up to you to take care of it even though you may not even be aware that it is there. We tend to only to think of our immune system when it is not working-when suffer mild or severe health challenges.
Without getting into too much detail, our immune system is a complex series of cells that all communicate with each other and must be balanced correctly in order for us to stay healthy. AHCC is able to encourage the helpful cells such as the natural killer (NK) cells while suppressing the ones that foster problems.
I am in clinical practice on a daily basis and use AHCC in almost every one of my patients. It is very versatile because of its effects on the immune system.
A Company Committed to Excellence
If everything I just told you wasn’t enough to convince you that AHCC should become part of your daily armamentarium, then here’s more fuel. AHCC is produced by a chemical company that is committed to excellence in manufacturing and most importantly in research. They have supported research at hospitals around the world, including local ones such as Columbia University, Harvard University and the University of California.
In fact, I just returned from a trip to Sapporo, Japan where the product is made and where each year, a team of scientists and medical professionals gather to discuss the latest research on AHCC, GCP, and oliganol-all products made by the same company. This was the 13th annual symposium and was attended by close to 1000 professionals.
It is remarkable to me that this company is able to produce such well-documented research while still being a nutritional supplement company, which shows it can be done. To me, this is the sign of a nutritional supplement worth recommending. If it does what it says it is supposed to do and has research to support those claims, than that is something you want in your daily diet.
So, even though you may never have given your immune system a second thought, you really should; and the best way to help it out is by taking AHCC on a daily basis, just like I do. I recommend 500 mg per day in the summer months and 1500 per day in the winter months as a simple preventive. Stay healthy!
About the Author
Fred Pescator, M.D., a traditionally trained physician practicing nutritional medicine, is President of the AHCC Research Association. He is the author of The Hamptons’ Diet, Thin For Good and Feed Your Kids Well. Dr.Pescator lectures around the world, and has been featured on such shows as The View, The Today Show, Deborah Norville, The O’ Reilly Factor, and Extra. Recent interviews include Woman’s Health and Fitness, Let’s Live, the New York Times, the Wall Street Journal, Fortune and more. He is also the author of numerous papers and magazine articals. Dr.Pescator is actively involved in clinical research , and is instrumental in developing and clinically testing many of the leading nutritional products. He is the President-Elect of the International and American Association of Clinical Nutritionists and a member of the National Association of Physician Broadcasters.
The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Sytrinol can lower Cholesterol by 27% - 34%
September 20, 2005 09:56 AM
Sytrinol – MultiPronged Heart Health
According to the American Heart Association, more than 60 million Americans suffer from on of more forms of cardiovascular imbalances. When we add in those individuals with blood cholesterol concerns, we see over 100 million Americans who may be in need of specific diet and lifestyle recommendations for achieving and maintaining heart health.
Aside from the generalized recommendations that we typically hear for heart health (lose weight, exercise more, and eat less fat and more fruits and vegetables) There are a number of potentially beneficial dietary supplements that may help to maintain cholesterol levels in the normal range. Among supplements there is a wide range of safety and efficacy between products—but a newer product called Sytrinol stands out for its clinical effectiveness.
Sytrinol is a patented blend of polymethoxylated flavones (from citrus) and tocotrienols (from palm fruit). One of the factors that sets Sytrinol apart from existing natural products for heart health is its multipronged approach to controlling multiple factors related to overall heart health—including control of cholesterol, cellular irritation, oxidation, triglycerides, and others.
While it is unarguable that cholesterol is an important contributor to overall heart health, it couldn’t be further from the truth that cholesterol is the “only” or even the most important factor when it comes to protecting your heart. Did you know that approximately HALF of all serious heart challenges each year are experienced by people with NORMAL cholesterol levels? If Cholesterol is not to blame, then what is?
In addition to total cholesterol levels (the “number” that you may know as 200 to 240 of other values in “mg/dl” units), we know how that LDL and HDL matter a lot (Low-density lipoprotein—the “bad” cholesterol, and High-density lipoprotein—the “good” cholesterol). We also know that some forms of the bad and LDL can be “Badder” than others—specifically those with lots of structural protein called “apolipoprotein B” (which tends to encourage LDL cholesterol to become embedded in your blood vessel linings—bad!). In addition to our total cholesterol, LDL, HDL, and the various apoproteins, we also need to know our triglyceride levels, our levels of cellular irritation, what our free radical load looks like, and what our antioxidant defenses are. Sytrinol addresses each of these important aspects of heart and health simultaneously.
The Sytrinol Solution
Polymethoxylated Flavones (PMFs) in Sytrinol are just what they sound like – flavonoid compounds with extra methoxy groups compared to “regular flavones. Like all flavonoids, the PMFs deliver potent antioxidant activity, but the PMF version is about three times more potent in its ability to address cholesterol levels (20% - 30% reduction in clinical Studies). The two primary PMFs are nobiletin and tangeretin.
In addition to the PMFs, Sytrinol contains palm tocotrienols—one of the most potent antioxidant nutrients known. An interesting effect of tocotrienols is a reduction in cholesterol synthesis in the liver—by a mechanism similar to (but safer than) the commonly utilized mechanism of inhibition of the HMG-CoA Reductase Enzyme.
Sytrinol is known to work via several unique mechanisms to reduce triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL). First, by reducing DGAT activity (Diacylglycerol acetyl transferase) and increasing liver PPAR (Peroxisome porliferator-activated receptor)—Sytrinol can reduce overall synthesis of TG (DGAT inhibition). The overall effect is to reduce TG levels in the blood by two complementary mechanisms.
In terms of LDL effects, Sytrinol also reduces both Apolipoprotein B levels (ApoB—needed for the synthesis of LDL particles) and MTTP levels (microsomal triglyceride transfer protein-needed to transfer fat into the new LDL particles). By reducing levels of both these tructural LDL components, Sytrinol reduces overall LDL levels, and thus total cholesterol levels, in the blood.
The clinical results behind Sytrinol are impressive—showing a reduction in levels of total, LDL, and triglycerides by 27% - 34% within 4 weeks. In one of these studies, ApoB levels were reduced (suggesting reduced LDL) and ApoA1 levels were increased (suggesting increased HDL)—as would be expected based on the biochemistry of PMFs and tocotrienols.
Sytrinol is also wonderfully safe—and at the effective dose of 300mg daily, users will benefit from its multipronged effects. One aspect of Sytrinol safety that I especially like is the finding that, unlike some flavonoids like naringin from grapefruit, there are no known risks of drug interactions with the form of citrus derived PMFs found in Sytrinol (certain grapefruit flavonoids can interfere with liver enzymes needed to metabolize many prescription drugs).
Not since Red Yeast Rice was removed from the market by the FDA, have we had a truly effective, multimechanism solution for cholesterol control (and nearly total heart health). There are certainly other options for addressing heart health and cholesterol levels, but among the available choices, such as policosanol, guggulipid, niacin, and plant sterols, we’re looking at about half the cholesterol-lowering ability (10% - 15% in most cases) compared to Sytrinol. If youre in the “borderline” zone of cholesterol levels (about 240mg/dl and below), you should absolutely consider Sytrinol to keep your cholesterol levels under control.
Kurowska EM, manthey Ja. Hypolipidemic effects of absorption of citrus polymethoxylated flavones in hamsters with diet-included hypercholesterolemia. J Argic food chem.. 2004 may 19;52(10):2879-86.
Kurowska EM, manthey Ja, Casaschi A, Theriault AG. Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, Tangeretin. Lipids 2004 feb;39(2):143-51.
Manthey JA, Grohmann K, Montanari A, Ash K, Manthey CL, Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human moncytes. J Nat Prod. 1999 mar;62(3)441-4.
Mora A, Paya M, rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem Parmacol. 1990 Aug 15;40(4):797-7.
Takanaga H, Ohnishi A, Yamada S, Matsuo H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol exp. Ther. 2000 Apr;293(1):230-6.
By: Shawn M. Talbott, PH.D.
Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Quercetin and Bromelain - for better health.
July 04, 2005 10:28 AM
Down-regulates the Body’s Response to Environmental challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10
Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges.
Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures.
Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13
Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16
Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of free-radicals such as hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19
Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.*
In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.
Holy Basil - For Natural Stress Reduction and COX-2 Inhibition
June 29, 2005 01:02 PM
Skyrocketing stress is one of our nation’s most pervasive public health problems. Daily stress can cause imbalances in inflammatory COX-2 production and cortisol levels, which can influence blood sugar changes and, ultimately, result in challenges to our health. To regain balance, Source Naturals introduces HOLY BASIL, a legendary Ayurvedic herb that is making news for its ability to inhibit the inflammatory COX-2 enzyme, balance cortisol levels and normalize blood sugar. HOLY BASIL is rich in beneficial compounds—such as rosmarinic acid and eugenol—which work together to reduce stress. This herb also typically contains ursolic acid, shown to inhibit COX-2 in in vitro research. As a result, HOLY BASIL has a positive effect on mental well-being, and can support minor pain relief from everyday activities. Source Naturals brings you this special herb, used daily in India by millions, in a high-potency, 450 mg extract tablet.
Stress, Blood Sugar and Nervous System Protection
For over five millennia, Tulsi (holy basil) has been used to improve digestion and restore imbalances of the body and mind. Now research has documented that HOLY BASIL may do this by decreasing levels of cortisol, a hormone produced and secreted by the adrenal glands. Nicknamed the “stress hormone,” cortisol production increases in response to chronic stress. Cortisol triggers the body to make glucose from amino acids, which causes blood sugar to rise. Through normalizing cortisol levels in times of stress, holy basil may prevent not only the mood changes associated with stress, but also prevent the increases in blood sugar that researchers say can contribute to numerous health imbalances affecting more than half of all Americans. HOLY BASIL has also been found to normalize neurotransmitter levels in the brain. Researchers found in animal studies that HOLY BASIL counteracted stress-induced changes in neurotransmitters and enzymes. Stress leads to a positive increase in brain serotonin levels, increases in dopamine levels and increases in SDH (succinate dehydrogenase) levels, while holy basil may help people maintain normal levels of these brain chemicals in times of stress. Another study found that animals that received the extract showed significant normalization of epinephrine, norepinephrine, serotonin, MAO, and SDH. Epinephrine and norepinephrine are used in coping with stress. The researchers suggest that when dopamine levels rise, these two neurotransmitters may be replenished since dopamine is a precursor for their synthesis. This may be the mechanism by which holy basil assists with stress adaptation.
A Powerful Adaptogen
HOLY BASIL is classified as a premier “adaptogen,” an herb that can normalize body processes and restore overall health by maintaining body systems. Adaptogens support our systemic response to stress and give us stamina. HOLY BASIL is not to be used if you are pregnant, breastfeeding, or if you may become pregnant. Taking personal responsibility for your health and exploring safe natural alternatives to support prevention is the basis for the current revolution in health care. And health food outlets are the center of this wellness revolution. It is here that Source Naturals HOLY BASIL and hundreds of other advances in nutritional science and natural health can be found.
GLISODIN POWER - Superoxide Dismutase (SOD)
June 29, 2005 10:54 AM
Most people know that antioxidants found in food are critical for health and longevity, but did you know that the human body has its own antioxidant defense system? Superoxide dismutase (SOD) is an internal antioxidant manufactured by the body as the first line of defense against free radical damage. Unfortunately, high levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help.
Source Naturals introduces GLISODIN POWER, an innovative approach to antioxidant supplementation. Scientific research shows that GliSODin® supports the body’s own production of superoxide dismutase. GLISODIN POWER is a patented, orally effective, 100% vegetable compound comprised of gliadin, a wheat protein extract bound to superoxide dismutase derived from canteloupe.
Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to your cells and tissues. Free radicals have unpaired electrons that can damage living cells and compromise the proper function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of antioxidants to minimize this negative effect.
First Line of Defense
There are two classes of antioxidants-external and internal. External antioxidants are supplied to the body by the foods we eat or the supplements we take. They include vitamins A, C and E, selenium, and other antioxidants found in fruits and vegetables. Internal antioxidants are naturally present in every cell of your body. The internal antioxidant defense system includes the enzymes superoxide dismutase (SOD), catalase and glutathione peroxidase. They are the first line of defense against oxidative stress. SOD transforms the superoxide radicals into ions that are less reactive. The superoxide radicals, which are byproducts of normal cell processes, can damage cells if their levels are not controlled. The other enzymes then transform the less reactive ions in a process called dismutation. The superoxide dismutase enzyme gets its name from this process. Research indicates that SOD plays an important role in protecting neurons from oxidative damage.
Super Antioxidant: SOD
SOD levels decline with age, while free radical production increases. SOD occurs naturally in barley grass, broccoli, Brussels sprouts, cabbage, wheat grass, melon and most green plants. Unfortunately, when taken orally the SOD enzyme is usually destroyed in the digestive process. GliSODin is a new form of SOD that withstands the digestive process and promotes SOD production by the body. This breakthrough technology combines a vegetable source of SOD extracted from melon with gliadin, a wheat protein. Scientific studies have shown that GliSODin promotes the natural production of SOD in the body. Research has also shown that it protects against oxidative stress and provides an optimal defense against free radicals.
Innovative natural products such as GLISODIN POWER, are part of the Wellness Revolution. Taking personal responsibility for your health is at the heart of this revolution. Your local health food outlet is your source for nutritional education and quality products. Source Naturals is pleased to partner with these outlets to bring you the groundbreaking nutritional science of GLISODIN POWER.
Guggulsterones - Natural Support for Cholesterol Health
June 29, 2005 10:44 AM
Today’s lifestyle, with its high-fat, processed food diet, lack of exercise, and high stress levels, leaves you at risk for imbalanced cholesterol levels. Source Naturals is committed to your optimal health and longevity. That’s why we developed GUGGULSTERONES. GUGGULSTERONES is a natural solution to help keep your cholesterol levels in the normal range. Guggulsterones are compounds found in guggul, the resin of a shrub used in traditional Ayurvedic herbalism to support a healthy heart. Research shows guggulsterones help maintain cholesterol levels in the normal range by helping to promote bile production, which removes cholesterol from the blood. They also boost thyroid activity, which supports cholesterol regulation by the liver. Source Naturals offers you natural guggul extract, standardized to provide a clinically effective daily dosage. As one of the most important botanicals to support cardiovascular health, GUGGULSTERONES is at the heart of Source Naturals’ commitment to empower people to take charge of their own health.
Cholesterol, Guggulsterones and Bile Production
Much of the cholesterol made by your liver is utilized to create bile, a substance used in digestion to emulsify fats. Because excess cholesterol and triglycerides are excreted from our bodies in the form of bile, it is important to support the liver’s bile-producing mechanism. Research shows that certain guggul compounds— guggulsterones—help maintain cholesterol levels in the normal range and act at the farnesoid X receptor (FXR) to promote bile production. Guggulsterones appear to be farnesoid X receptor (FXR) antagonists. FXR is a bile acid receptor. If FXR is activated, this results in down-regulation of the amount of bile acids produced by the liver. Bile is made out of cholesterol, which gets used up when bile is produced. When bile levels are high, the production of more bile is slowed through negative feedback of the FXR pathway. As steroids, guggulsterones can enter the nuclei of liver cells and block FXR, which results in more bile production.
Guggulsterones and Thyroid Stimulation
Guggulsterones have been shown to stimulate thyroid activity in animal studies. This is important because 90% of individuals with sluggish thyroid glands also experience challenges to healthy cholesterol levels. Since the thyroid regulates the metabolic rate of many organs, when thyroid hormone levels are too low, the body’s overall metabolic rate declines. This impairs the liver’s ability to clear cholesterol from the bloodstream. The liver regulates cholesterol levels in blood as well as producing bile, and it contains thyroid hormone receptors. This is how the thyroid gland controls the metabolic rate of the liver. Several studies have shown that guggul supports normal cholesterol levels, including LDL, serum triglycerides, and HDL levels. Because normal levels of serum lipids, including cholesterol, are supported by increased circulating thyroid hormones, it is believed guggul works by stimulating the thyroid gland, in addition to its effects on bile production.
Clinically Effective Dosage
According to several clinical studies, the amount of guggulsterones used to maintain normal cholesterol levels is 75 mg per day, when taken with a diet low in saturated fats. This is the daily dose delivered by SOURCE NATURALS GUGGULSTERONES.
A Wellness Revolution in Cardiovascular Care
At a time when our cardiovascular health faces numerous lifestyle challenges, research into the remarkable heart-supportive properties of the plant world is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you nutritional benefits now available only through the natural products marketplace.
RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
June 24, 2005 05:34 PM
The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.
Bio-Aligned Antioxidant Support
RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.
Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.
Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.
Nourishing the Brain
Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.
Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.
The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.
Skin & Connective Tissue
Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.
Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.
Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.
DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.
Living Longer, Living Better Strategies for Wellness
Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.
Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.
Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf
Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein
Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts
Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric
Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE
Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc
Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf
VANADIUM W/CHROMIUM - Supports Healthy Blood Sugar Levels
June 24, 2005 05:15 PM
Today’s sedentary lifestyles and sugar-rich, nutrient-poor foods are contributing to the rise of obesity in our society. The result: challenges to your body’s system of balancing blood sugar levels and insulin activity. Maintaining a healthy diet and lifestyle helps keep blood sugar levels in the normal range, but sometimes you need nutritional support when you don’t have time to make those healthy food choices. Source Naturals, the science company, introduces VANADIUMW/CHROMIUM for blood sugar support. Research shows that these two important minerals help maintain normal blood sugar levels when used as part of your diet.
Vanadium works together with chromium to support healthy blood sugar levels. Research has shown that both of these important minerals play a key role in normal insulin function.
Vanadium: Balances Insulin Activity Vanadium, named after Vanadis the Norse goddess of beauty, belongs to a group of biologically important metals known as transition elements. These metals have a natural tendency to form complexes with organic compounds called coordination compounds that serve important biological functions.
Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. The sugar that remains in the blood can create problems by binding with protein molecules, resulting in damaged, non-functioning structures, in a process called glycation. Some evidence suggests that vanadium supports these vital metabolic processes because of its ability to mimic the actions of insulin.
More Absorbable Form of Vanadium
Absorption of dietary vanadium and supplemental vanadium is poor. It is estimated that less than 5% of dietary vanadium is absorbed. Organic forms of vanadium, such as bis-glycinato oxovanadium or BGOV, are recognized as being more absorbable. BGOV is an organically bound, bioavailable form of vanadium complexed with the amino acid glycine. Glycine, an amino acid found in the protein of all life forms, generates superior vanadium absorption.
Chromium: Supports Glucose Metabolism Chromium is a trace element the body needs in very small amounts, but it plays a significant role in human nutrition. Its most important function is to help regulate the amount of glucose in the blood. Insulin plays a role in this process, by regulating the movement of glucose out of the blood and into the cells. Chromium is a key constituent of the compound known as glucose tolerance factor (GTF). This mineral enhances the effectiveness of insulin, encouraging glucose to enter cells, where it can be burned for fuel.
Chromium participates in glucose metabolism by enhancing the effects of insulin. Insulin binds to insulin receptors on the surface of cells, activating those receptors and stimulating glucose uptake by cells. Through its interaction with insulin receptors, insulin provides cells with glucose for energy and prevents blood glucose levels from becoming elevated. Glucose buildup in the bloodstream is associated with adverse changes in lipid profiles and increased challenges for cardiovascular health. Some studies examining the effects of chromium supplementation on lipid profiles have observed reduction in serum total cholesterol, LDL cholesterol, and triglyceride levels. Source Naturals VANADIUM W/CHROMIUM includes ChromeMate®, a patented compound of chromium and niacin with proven GTF activity.
Taking responsibility for your health is at the heart of the wellness revolution. Sometimes life may seem like it’s passing you by and you may not have time to focus on staying healthy. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you products like VANADIUM W/CHROMIUM to help you maintain a healthy balance.
Anderson, R.1998. Chromium, glucose intolerance and diabetes. Journal of the American College of Nutrition 17(6):548-555. Jellin, J., et al. 2004. Vanadium Monograph. Pharmacists Letter/Prescribers Letter Natural Medicines Comprehensive Database. Therapeutic Research Facility. Nandhini, S., et al. 1993. Insulin-like effects of bis-glycinato oxovanadium complex on experimental diabetic rats. Indian Journal of Biochemistry and Biophysics 30:73-76.
CLA and Body Fat
June 22, 2005 09:50 PM
CLA and Body Fat
Of all the health concerns facing Americans today, few are as important and daunting as weight loss and body fat. In the 1980s, Americans gained an average of eight pounds each. That’s on the order of 1 million tons of flab—2 billion total American pounds.45 So large is the current girth that as many as two in three Americans could be termed overweight.46 Being overweight and having excess fat increases the risk of heart disease, some forms of cancer and diabetes. That collection of health challenges would be difficult enough, but being overweight has many problems that accompany it, including battles with self-esteem.
Let’s give a historical example of this story. The emotional power of being perceived as too fat is caught with pathos in the life of former U.S. President William Howard Taft. Taft, who is the only man to serve as both president and as chief justice of the Supreme Court, was noted for his honesty and his integrity. The nation mourned his death, but much of his internal story focused on his battle with weight. One editorial cartoonist showed the island of Cuba tipping under his girth. Once, when he visited Japan, an entire village worked together to pull his rickshaw up a hill. When he married, his personal esteem showed when he told his wife that “I shall worry you so much with my appetite that you must gain strength to meet the trial.”
Taft refused to be seen on a horse because of how awkward he looked. At one point, he lost 75 pounds, but, like so many others, ended up gaining that amount back , and more, during the next 10 years. He died of athero s c l e rosis, something associated with being ove rwe i g h t .4 7 The tragedy of Taft is that, like so many suffering with weight trouble, he seemed to let it damage his self w o rth, when he was a great asset to his nation and to others. History and culture put into us that being overweight means lacking in self-control and being a glutton, when in reality this isn’t true. So many more factors are involved. Each person has a different metabolism. Certain nutrients can meet different needs, and a lack of those nutrients can lead to fat retention. CLA may be one of those nutrients, one of those factors in our diets that can change our shapes and that have nothing to do with self-control, just nutritional luck and knowledge. In a study of rats, 28 days after beginning the study, body fat in those that ate CLA was 58 percent less than in those who didn’t consume any (10.13 percent body fat versus 4.34 percent body fat, a highly significant difference). Also, the percent of muscle was about one percent more in animals that ate CLA. The weights of both sets of animals were about the same.48 (Muscle weighs more than fat. This can mean that you won’t necessarily lose weight with CLA, but would gain muscle mass, which is tighter and more shapely.) The research in this area is slightly newer, but it has been reproduced in studies on other animals.49 That more than one kind of animal has shown that body fat is lower with supplements of CLA indicates that it will likely benefit humans as well.
In July 1997, preliminary results of one of the first human studies involving CLA showed promising, preliminary results. For three months in 1997, 20 volunteers participated in a study, daily consuming an amount of slightly more than one gram of CLA at breakfast lunch and dinner. Three months later, their weights and body-fat percents were measured. Half of the group took a placebo. The average weight of the 10 who took CLA dropped by about five pounds (not enough to be statistically significant), but the body fat percentage dropped by about 15 to 20 percent, or from 21.3 percent of average body fat to 17 percent of body fat. Meanwhile, the group taking a placebo had little or no effect on either. Half of the people in the study were men and half were women. Two people in the study decided to drop out because they received unpleasant gastrointestinal upsets. One of those who dropped out was in the placebo group, the other in the group taking CLA.63
Nobody would suggest that CLA supplementation would be a pill freeing you to sit slug-like on the couch to watch M*A*S*H* re runs. A healthy, weight-conscious lifestyle requires many factors including exercise. As far as science can tell, CLA may not be essential the way certain vitamins are. If you consume no vitamin C, you can expect to get scurvy and die. There are no known deficiency diseases associated with an absence of CLA.
Japanese consumers, for example, get very little CLA in their diets, but they also eat food very low in fat, and their lives are among the longest in the world.50 So, the role of CLA supplementation in regulating weight is most useful for those with a typically high-fat Western diet. As the science grows, it seems clear that CLA will lead to better health and more hope for people struggling with body fat.