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Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592)

Date: December 06, 2023 04:55 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: six top-notch supplements that can help you achieve your goals.

If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.

For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before.

Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level.

For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence.

In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select.

Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery.

Oxidation and Free Radical Damage

A fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases.

Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level.

As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup).

Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease

Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being.

So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully.

Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging.

While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively.

Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery:

Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results.

BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - leucine, isoleucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair.

Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery.

Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline.

Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health

Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results.

Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein.

Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health.

In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.

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Date: August 04, 2023 02:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why Your Sodium to Potassium Ratio Is Important

The typical Western diet is largely comprised of processed foods, which are notoriously high in processed table salt. This results in an imbalance in the sodium to potassium ratio, a significant health concern. Sodium is necessary for a variety of bodily functions; however, too much can be detrimental, leading to hypertension and other cardiovascular diseases. Simultaneously, potassium is often neglected, despite its crucial role in muscle function, nerve signaling, and balancing fluids.

The general dietary advice suggests a potassium to sodium intake ratio of 3:1. However, the reality in diets, particularly those in America, often sees this ratio inverted. The excessive sodium consumption is linked to a myriad of health complications, including high blood pressure and heart disease. Conversely, potassium, a mineral that aids in nerve function and muscle control, is consumed in insufficient quantities. This is a troubling trend that underscores the importance of dietary change towards natural, unprocessed foods.

The importance of potassium is often overshadowed by the emphasis on limiting sodium for reducing chronic disease risk factors. Potassium plays an essential role in maintaining healthy blood pressure levels by counteracting the effects of sodium. Furthermore, the mineral is crucial for other functions like heart and muscle cell functioning, nerve transmission, and maintaining fluid balance.

A study published in the New England Journal of Medicine discovered that individuals with the lowest risk for heart complications or death from any cause were those consuming between four to six grams of sodium per day. This is a fascinating discovery, as this intake is significantly higher than the U.S. daily recommended limits. It suggests a need for a reconsideration of current sodium intake guidelines.

Another consideration to balance the sodium-potassium ratio is the type of salt consumed. Unprocessed, natural salts like sea salt and Himalayan salt contain higher potassium levels compared to standard table salt. These natural salts provide a variety of minerals and trace elements that contribute to our overall health and wellness. It's crucial to note that switching to natural salt should be part of a broader shift towards a diet rich in fresh, unprocessed foods.

Why You Should Focus on Increasing Potassium

While it's beneficial to monitor and moderate sodium intake, it's equally important to shift our focus towards increasing potassium consumption. Potassium-rich foods, such as leafy green vegetables, bananas, potatoes, and beans, not only contribute to a well-rounded and nutritious diet but also help in maintaining an optimal sodium-potassium balance in the body. A high potassium intake can counteract the effects of sodium, aiding in blood pressure regulation and reducing the risk of cardiovascular diseases. Moreover, an elevated potassium level supports various bodily functions, including nerve transmission, muscle contraction, and fluid balance. Thus, prioritizing potassium intake forms a cornerstone for an overall healthier dietary approach. It is recommended that individuals consume 5 grams of potassium daily and potassium to salt ratio should be 2 to 1. To boost potassium intake, one can take a potassium supplement or add the following foods to their diet or both: Watermelon, Orange juice, Boiled red potatoes, Avocado, Bananas, Cantaloupe, Oranges, Coconut water, Tomatoes, Yogurt, Winter squash, and Wild-caught salmon.

Why Low-Salt Advice Can Be Harmful

Contrary to popular belief, adhering to low-salt advice can sometimes pose risks to certain individuals. While it is true that excessive sodium intake can lead to high blood pressure and heart problems, sodium still plays a vital role in our bodies. It assists in nerve conduction, muscle contraction, and maintaining the body's fluid balance.

In fact, low sodium levels in the body, a condition known as hyponatremia, can lead to symptoms such as headache, nausea, fatigue, and in severe cases, coma or even death. Moreover, a low-salt diet may lead to increased levels of cholesterol and triglycerides, hormonal imbalances and insulin resistance. This can potentially elevate the risk of developing cardiovascular disease.

Low-salt diets can also exacerbate the risk of certain health conditions. For instance, individuals with conditions like Addison's disease or certain kidney disorders, where the body struggles to maintain a balance of electrolytes, might find a low-salt diet harmful.

Therefore, it is crucial to balance the intake of sodium, considering both the potential risks associated with too much, or too little, sodium. The key is to consume sodium from natural and unprocessed sources, such as Himalayan salt, fruits, vegetables, grains, and lean meats, which also provide a host of other nutrients necessary for overall health. As with most things in nutrition, moderation and balance seem to hold the answer rather than extreme restriction. The RDA - recommended daily allowance of sodium is 3.5 grams. It is advised to consume 3.5 grams of natural salt each day by way of foods or combination of foods plus Himalayan salt to reach that goal.

The Impact of Excessive Salt Intake on Certain Health Conditions

While moderate salt intake is vital for normal physiological functions, its excessive consumption can have detrimental effects, particularly for individuals with certain health conditions. For instance, endocrine disorders, high aldosterone levels, Cushing's syndrome, and elevated cortisol levels can all heighten the body's sensitivity to sodium, making it even more essential to monitor and limit salt intake.

Endocrine disorders, which involve imbalances in the body's hormone production, can often lead to increased sodium retention, exacerbating issues of water retention and swelling. Similarly, high aldosterone levels, a hormone that regulates sodium and potassium balance, can cause the body to retain excessive sodium, leading to high blood pressure and potential damage to the cardiovascular system.

Cushing's syndrome, a condition characterized by excessive cortisol production, can lead to a host of symptoms, including high blood pressure and rapid weight gain, both of which can be intensified by high sodium intake. The excessive cortisol found in Cushing's syndrome promotes sodium retention, further elevating the risk for hypertension.

Similarly, elevated cortisol levels, even outside of Cushing's syndrome, can lead to heightened sodium retention, contributing to high blood pressure, fluid retention, and an imbalance of electrolytes. Therefore, individuals with these conditions should be particularly mindful of their sodium intake.

In these scenarios, reducing salt consumption can help mitigate the associated health risks and symptoms. Switching to a diet rich in whole, unprocessed foods, and taking conscious steps to limit the use of added table salt can play a crucial role in managing these health conditions. As always, it is essential to seek personalized advice from a healthcare professional, as individual needs may vary.

In summary, while salt is often villainized in the health community, its consumption, especially from natural sources, is vital for maintaining bodily functions like nerve conduction, muscle contraction, and fluid balance. However, excessive or inadequate sodium intake can have adverse health effects, such as hypertension, imbalances in cholesterol and triglycerides, and even hyponatremia in severe cases. Certain health conditions, including endocrine disorders, high aldosterone levels, Cushing's syndrome, and elevated cortisol levels, can also exacerbate these risks, making it crucial for individuals with these conditions to carefully monitor their salt intake. On the other hand, increasing potassium intake can help maintain an optimal sodium-potassium balance, reducing blood pressure and lowering the risk of cardiovascular diseases. In a nutshell, moderation and balance are key in sodium consumption, but the emphasis should be on consuming more potassium-rich foods to ensure your potassium intake is higher than sodium levels which will ensure a healthier dietary approach.

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Date: October 31, 2022 05:02 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Do You Know How Important Magnesium Is For The Body?

You may not have realized it, but magnesium is an essential mineral for your body. It aids in energy production and metabolism, muscle contraction, nerve impulse transmission, and bone mineralization. Magnesium is also a required cofactor for an estimated 300 enzymes. That means it helps catalyze reactions like fatty acid synthesis, protein synthesis, and glucose metabolism. Not to mention, magnesium status is also important for regulation of calcium balance through its effects on the parathyroid gland. Whew! As you can see, this mineral is pretty important stuff. Read on to learn more about why magnesium is so critical for our health.

Magnesium and Energy Production

One of the most important functions of magnesium is that it helps us produce energy. Every single cell in our bodies need energy to function properly, and magnesium plays a key role in the process of converting the food we eat into that much-needed energy. For example, magnesium is involved in breaking down carbohydrates into glucose which can then be used for energy by the cells.

Magnesium and Muscle Functioning

In addition to helping produce energy, magnesium is also necessary for proper muscle functioning. This mineral helps muscles relax after they contract as well as regulates electrolyte balance in the body. electrolyte imbalance can lead to muscle cramping, spasms, or even irregular heartbeats, so it's crucial that we maintain healthy levels of magnesium to keep our muscles functioning properly.

How to Get More Magnesium

Now that you know all of the important functions that magnesium plays in our bodies, you're probably wondering how you can make sure you're getting enough of this essential mineral. The best way to ensure adequate magnesium intake is through diet since our bodies cannot produce this mineral on their own. Some good dietary sources of magnesium include leafy green vegetables, legumes, nuts and seeds, whole grains, dairy products, fish, and meat. You can also get your recommended daily intake of magnesium through supplements if you feel like your diet is lacking or if you have a medical condition that requires extra magnesium (such as diabetes).

As you can see, magnesium is an essential mineral with many vital functions in our bodies. from helping produce energy to regulating electrolyte balance, this nutrient plays a big role in keeping us healthy and function properly both physically and mentally. Make sure you are getting enough magnesium in your diet by consuming foods like leafy greens, legumes, whole grains, dairy products ,and nuts or by taking supplements if necessary. Your body will thank you!

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Date: October 28, 2022 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: NOW Liquid Magnesium with Trace Minerals - The health benefits of magnesium and other trace minerals

Magnesium is a mineral that is necessary for the body to perform normal biochemical reactions.* It is also necessary for the maintenance of healthy electrolyte balance and healthy neuro-muscular function.* Magnesium and other trace minerals are often found in nature together, and so it can be difficult to get the right amount of magnesium if you are not getting enough of the other trace minerals as well. This is where NOW Liquid Magnesium with Trace Minerals comes in.

NOW Liquid Magnesium with Trace Minerals is a natural mineral concentrate sourced from the Great Salt Lake and produced by using a proprietary solar evaporation process. This process also removes 99% of the naturally occurring sodium, while preserving its remaining 72 naturally occurring Trace Minerals in their bioavailable ionic forms. So, if you are looking for a way to ensure that you are getting enough magnesium and other trace minerals, then NOW Liquid Magnesium with Trace Minerals is a great option.

Health Benefits of Magnesium*

There are many health benefits associated with magnesium.* Some of these benefits include:

• -Helping to maintain healthy blood pressure levels*
• -Helping to maintain healthy bones and teeth*
• -Helping to reduce the risk of developing type 2 diabetes*
• -Helping to reduce the severity of migraine headaches*

And these are just some of the benefits associated with magnesium.* If you are not getting enough magnesium from your diet, then taking a magnesium supplement like NOW Liquid Magnesium with Trace Minerals can help you to improve your overall health.* In addition, since NOW Liquid Magnesium with Trace Minerals also contains 72 other bioavailable ionic trace minerals, you can be confident that you are getting a wide range of nutrients that are essential for good health.

In conclusion, NOW Liquid Magnesium with Trace Minerals is a great way to ensure that you are getting enough magnesium and other essential nutrients.* If you are looking for a way to improve your overall health, then this product is definitely worth considering.* Thanks for reading!

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Date: September 30, 2022 12:37 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Benefits of NOW Clinical Cardio

If you're looking for a comprehensive way to support optimal cardiovascular health, look no further than NOW Clinical Cardio. This powerful combination of targeted nutrients and botanicals helps promote healthy cardiovascular structures and functions.* With L-carnitine and CoQ10 to support energy production in the heart, hawthorn and MegaNatural®-BP™ grape seed extract to support blood pressure already within the normal range, and MK-7 to help maintain arterial flexibility, Clinical Cardio offers a broad range of benefits for those looking to maintain a healthy heart.*

How NOW Clinical Cardio Works

NOW Clinical Cardio is a powerful formula that contains a combination of targeted nutrients and botanicals that are known to support optimal cardiovascular health.* The nutrients and botanicals in Clinical Cardio work synergistically to provide a comprehensive approach to maintaining a healthy heart.*

L-carnitine is an amino acid that is synthesized in the liver from methionine and lysine. L-carnitine plays an important role in energy production by transporting fatty acids into the mitochondria where they can be used for fuel.* In addition, L-carnitine has been shown to support healthy heart function and protect against oxidative stress.*

CoQ10 is another important nutrient for energy production, as it is involved in the electron transport chain in mitochondria.* CoQ10 levels have been shown to decline with age, so supplementation may be especially important for older adults.* Like L-carnitine, CoQ10 has also been shown to support healthy heart function while protecting against oxidative stress.*

Hawthorn is an herb that has been used traditionally for centuries to support cardiovascular health. Hawthorn's primary mechanism of action is vasodilation—the widening of blood vessels—which supports healthy blood pressure already within the normal range.* Additionally, hawthorn has antioxidant activity and can help protect the heart from free radical damage.*

MegaNatural®-BP™ grape seed extract is a patented extract of whole red grapes that has been shown in clinical studies to help maintain already healthy blood pressure levels.* MegaNatural®-BP™ contains polyphenols—powerful plant compounds with antioxidant activity—which may help explain its beneficial effects on blood pressure levels.*

MK-7 is a form of vitamin K2 that is derived from natto, a traditional Japanese fermented food. Vitamin K2 is involved in calcium metabolism and has been shown to promote arterial flexibility by keeping calcium hydroxyapatite out of soft tissues such as arteries.* By promoting arterial flexibility, MK-7 helps maintain healthy blood flow throughout the body.*

Conclusion: NOW Clinical Cardio is a comprehensive formula that contains nutrients and botanicals that are known to support optimal cardiovascular health. With L-carnitine and CoQ10 for energy production, hawthorn for blood pressure support, MegaNatural®-BP™ grape seed extract for antioxidant protection, and MK-7 for arterial flexibility, Clinical Cardio offers a broad range of benefits for those looking to maintain a healthy heart. Try it today!*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Date: September 14, 2022 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Many Benefits of Chia Seeds, Omega-3, and more

You might know chia seeds best as the things that grow on those weird Chia Pets you can buy at the store. But did you know that chia seeds are actually really good for you? Yes, those little seeds that make your Chia Pet grow a green coat are actually packed with essential nutrients. Lets take a look at some of the many benefits of chia seeds.

Chia seeds are an excellent source of fatty acids. In fact, nearly two-thirds of the fat in chia seeds is comprised of Omega-3s. Omega-3 fatty acids are essential for maintaining heart health, preventing chronic diseases, and reducing inflammation throughout the body. Chia seeds are also a great source of fiber. Fiber is important for keeping our digestive system healthy and preventing constipation. Additionally, fiber can help to lower cholesterol levels and regulate blood sugar levels.

Another benefit of chia seeds is that they are a great source of protein. Protein is essential for building and repairing tissues, muscles, and organs. It's also necessary for producing enzymes and hormones. And because chia seeds contain all nine essential amino acids, they are considered a complete protein source. This makes them especially beneficial for vegetarians and vegans who may have difficulty getting enough protein from their diet.

Finally, chia seeds are rich in vitamins and minerals like calcium, phosphorus, magnesium, and manganese. These nutrients are essential for maintaining strong bones and teeth, balancing electrolytes, and regulating blood pressure. They also play a role in energy production and metabolism.

As you can see, there are many reasons to add chia seeds to your diet. Whether you sprinkle them on your cereal or add them to your favorite smoothie recipe, you're sure to benefit from their nutrient-rich goodness. So go ahead and give them a try - your body will thank you!

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Date: July 20, 2022 03:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Antioxidants to Protect Your Body from Non Ionizing Radiation

Non ionizing radiation is all around us. It comes from many different sources, including our cell phones, laptops, and other electronics. While it is not as dangerous as ionizing radiation, it can still do a lot of damage to our bodies. This damage can lead to health problems down the road. That's why it's important to protect yourself with antioxidants. We will discuss the three best antioxidants to protect your body from non ionizing radiation: vitamin C, NAC, and greens!

What is non ionizing radiation and why should we be concerned about it?

Non-ionizing radiation is a type of electromagnetic radiation that does not have enough energy to remove electrons from atoms or molecules. Despite its relatively low energy, non-ionizing radiation can be harmful to human health. This is because it can cause damage to DNA and other cellular structures. Prolonged exposure to non-ionizing radiation has been linked to an increased risk of cancer, as well as other health effects such as eye damage, skin burns, and interference with the body's natural electrical systems. While the risks associated with non-ionizing radiation are typically lower than those associated with ionizing radiation, it is still important to take steps to reduce exposure when possible. For example, individuals can limit their exposure to non-ionizing radiation by avoiding unnecessary x-rays, using cell phone hands-free devices, and keeping laptops at a distance from the body. By taking these simple precautions, we can help reduce our risk of developing health problems from non-ionizing radiation exposure.

How to protect yourself from non ionizing radiation?

Extended exposure to certain types of non-ionizing radiation can be harmful. For example, prolonged exposure to ultraviolet (UV) radiation can damage the DNA in cells and lead to skin cancer. Additionally, high levels of microwave radiation can cause thermal injuries, such as burns. To protect yourself from harmful non-ionizing radiation, it is important to limit your exposure and take precautions to reduce your risk. For example, you can avoid prolonged sun exposure by wearing sunscreen and staying in the shade. You can also limit your exposure to microwave radiation by avoiding cell phone use and standing at least three feet away from microwave ovens while they are in use. By taking these simple steps, you can significantly reduce your risk of harm from non-ionizing radiation.

The best antioxidants for protecting your body from non ionizing radiation?

When it comes to protecting your body from non ionizing radiation, vitamins C and E are often thought of as the best antioxidants. However, studies have shown that glutathione (GSH) and N-acetyl cysteine (NAC) may be more effective. GSH is a potent antioxidant that helps to protect cells from damage, and NAC has been shown to increase GSH levels in the body. Both of these nutrients are found in leafy greens, making them an excellent addition to your diet. Green tea is also a good source of antioxidants, and regular consumption has been linked with a reduced risk of cancer. Whether you're exposed to non ionizing radiation on a daily basis or just want to boost your antioxidant intake, adding more greens to your diet is a good place to start.

Other ways to reduce your exposure to non ionizing radiation?

There are a number of ways to reduce your exposure to non ionizing radiation. One is to simply turn off routers and other devices when they are not in use. Another is to move cell phones out of the room where you sleep, or at least keep them on airplane mode during the night. If possible, it is also advisable to avoid using microwave ovens and instead opt for stove-top cooking. Additionally, there are a number of newer devices on the market that emit low levels of radiation, so it is worth doing some research to see if these might be a better option for you. Ultimately, the best way to reduce your exposure to radiation is to be aware of the sources around you and take steps to minimize your exposure.

Non-ionizing radiation is a type of electromagnetic radiation that has been linked to several health risks, including cancer. While the risks associated with non-ionizing radiation are typically lower than those associated with ionizing radiation, it is still important to take steps to reduce exposure when possible. By taking simple precautions, such as avoiding unnecessary x-rays and using cell phone hands-free devices, we can help reduce our risk of developing health problems from non-ionizing radiation exposure. Additionally, there are a number of ways to reduce our exposure to this type of radiation, including turning off routers and other devices when they are not in use, moving cell phones out of the room where we sleep, and avoiding microwave ovens. By being aware of the sources of non-ionizing radiation around us and taking steps to minimize our exposure, we can help protect ourselves from its harmful effects.

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Date: May 11, 2022 12:19 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How Melatonin Can Support a Healthy Sleep Cycle and More

Did you know that melatonin is a powerful free radical scavenger? This means that it helps protect the body from damage caused by harmful molecules called radicals. Melatonin is also naturally produced in the pineal gland and is present in high amounts in the GI tract. We will discuss some of the ways that melatonin supports health and wellness.

Melatonin and the body

Melatonin is a hormone that is produced by the pineal gland in the brain. It is responsible for regulating the body's internal clock, or circadian rhythm. The production of melatonin increases at night, and decreases during the day. This hormone is also available in supplement form, and is often used to treat jet lag or insomnia. When taken as a supplement, melatonin works by resetting the body's internal clock, making it easier to fall asleep and stay asleep. Additionally, melatonin may also help to reduce anxiety and improve mood. As a result, this hormone plays an important role in regulating the body's sleep-wake cycle.

How does melatonin support a healthy sleep cycle?

Melatonin is a hormone that help regulate the sleep cycle. The production of melatonin is stimulated by darkness and inhibited by light. As a result, melatonin levels typically start to rise in the evening as the sun sets, and they remain high throughout the night. In the morning, light exposure causes melatonin levels to drop, helping to wake us up and start the day. Melatonin supplements can be used to help people who have difficulty sleeping and staying asleep. This hormone helps to reset the body's natural sleep cycle, making it easier to fall asleep and stay asleep. As a result, melatonin can be an effective way to support a healthy sleep cycle.

What are some of the other benefits of melatonin?

It can help to boost the immune system, protect against cancer, and reduce inflammation. Research suggests that melatonin may also have neuroprotective effects and could be beneficial for people with Alzheimer's disease or Parkinson's disease.

Tips for getting a good night's sleep

Most people need about seven to eight hours of sleep a day. However, many people find it difficult to get enough rest. There are a number of things you can do to improve your sleep habits. First, create a regular sleep schedule and stick to it as much as possible. Go to bed and wake up at the same time each day, even on weekends. Second, create a relaxing bedtime routine. This might include taking a warm shower, reading a book, or writing in a journal. Third, create a comfortable sleep environment by making sure your bedroom is dark, quiet, and cool. Fourth, avoid caffeine and alcohol before bed. Caffeine can make it difficult to fall asleep and stay asleep, while alcohol can disrupt your sleep cycle. Finally, try not to use electronic devices in bed. The blue light emitted by screens can interfere with your body's natural sleep rhythm and take melatonin. By following these tips, you can improve your chances of getting a good night's sleep.

Scientific research

Research on melatonin began in the 1950s, and since then, numerous studies have been conducted on its potential health benefits. Some of the most promising research has found that melatonin may help to prevent cancer. In one study, melatonin supplements were found to reduce the risk of breast cancer recurrence by half. Other research has shown that melatonin may help to protect against colon cancer, prostate cancer, and ovarian cancer. Additionally, melatonin has been shown to boost the effectiveness of chemotherapy drugs and radiation therapy.

While more research is needed to confirm the exact role of melatonin in cancer prevention, the available evidence suggests that it could play a significant role in protecting against this disease. Therefore, it may be worth considering supplementing with melatonin if you are at high risk for cancer or are undergoing treatment for this disease.

References:

• How Melatonin Can Support a Healthy Sleep Cycle and More. (n.d.).
• Tips for Getting a Good Night's Sleep. (n.d.).
• The Role of Melatonin in Cancer Prevention. (n.d.).
• Cancer Treatment Centers of America. (2017, September 28). Melatonin Shows Promise as Cancer Treatment Adjuvant | Cancer Treatment Centers of America.
• National Sleep Foundation. (2015, July 29). Melatonin and Cancer Risk - National Sleep Foundation.
• Mayo Clinic Staff.(2018, March 23). Melatonin: Is it effective?Retrieved from Mayo Clinic: Diseases & Conditions.."Melatonin."

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Date: April 29, 2022 03:10 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Kidneys and Your Health: Everything You Need to Know

The kidneys are two bean-shaped organs that sit in the lower back, on either side of the spine. They play a vital role in your health, filtering toxins from the blood and regulating fluid balance in the body. We will discuss everything you need to know about the kidneys, including common kidney problems and how to keep them healthy!

What are the common kidney problems

The kidneys are a pair of organs that filter waste products from the blood and excrete them in urine. They are also responsible for regulating fluid and electrolyte balance in the body. Kidney problems can range from mild to severe, and can be acute or chronic. Common kidney problems include kidney stones, urinary tract infections, and Nephrotic Syndrome. Kidney stones are small, hard deposits that form in the kidney when there is an imbalance of minerals in the urine. Urinary tract infections occur when bacteria enter the urinary system and multiply. Nephrotic Syndrome is a kidney disorder that causes the body to excrete large amounts of protein in the urine.Kidney problems can often be treated with medication, but in some cases, surgery may be necessary. Early diagnosis and treatment is important to prevent serious complications.

Acute renal failure

Acute renal failure is a sudden onset of kidney failure that can be life-threatening. The kidneys are responsible for filtering waste from the blood and balancing fluids in the body. When they are not working properly, waste can build up in the blood and cause serious health problems. Acute renal failure can be caused by a number of factors, including dehydration, infection, and certain medications. Symptoms include decreased urine output, swelling, fatigue, and confusion. If left untreated, acute renal failure can lead to coma and death. Early diagnosis and treatment is essential for a successful outcome.

Chronic renal failure

Chronic renal failure, or CRF, is a serious medical condition that affects the kidneys. In this condition, the kidneys become damaged and unable to function properly. As a result, toxins can build up in the body, causing a variety of symptoms. Some of these symptoms may include fatigue, bloating and swelling, nausea, diarrhea or constipation, poor appetite, changes in urination frequency or color, and anemia. Diagnosing CRF involves examining several factors like blood test results and overall medical history. Treatment for the condition typically involves managing any associated symptoms with medication or dietary changes. In some cases, dialysis may also be necessary to support patients with severe CRF. Overall, chronic renal failure is a serious but manageable condition that requires careful monitoring and management by patients and their healthcare providers.

Renal artery stenosis

Renal artery stenosis refers to a condition in which one or more of the arteries that deliver blood to the kidneys becomes narrowed or blocked. This can lead to a number of adverse health effects, including increased blood pressure, chronic kidney failure, and possibly even heart attack or stroke. While there are a number of possible causes for this condition, including genetic factors, certain lifestyle choices such as smoking can also increase the risk of developing renal artery stenosis. Fortunately, treatments are available for this condition, including medications and medical procedures like angioplasty. For those who are diagnosed with renal artery stenosis, early and effective treatment is essential for maintaining overall health and wellbeing.

Renal cancer

Renal cancer begins in the kidneys, which are a pair of bean-shaped organs that filter waste from the blood and produce urine. The most common type of renal cancer is clear cell renal cell carcinoma (RCC), which accounts for about three-quarters of all cases. RCC typically affects middle-aged adults and is more common in men than women. Other types of renal cancer include papillary renal cell carcinoma, chromophobe renal cell carcinoma, and collecting duct carcinoma. Treatment for renal cancer may include surgery, radiation therapy, chemotherapy, targeted therapy, or immunotherapy. The type of treatment will depend on the stage of the cancer and the patient's overall health. Early diagnosis and treatment is essential for the best possible outcome.

Polycystic kidney disease

Polycystic kidney disease, or PKD, is a complex condition that affects the kidneys and other organs in the body. This disorder occurs when small cysts grow in the kidneys, gradually interfering with their ability to filter waste products from the blood. As these cysts start to expand, they can cause a number of severe symptoms such as high blood pressure, chronic pain, nausea and fatigue. In some cases, PKD also results in serious complications such as renal failure or a stroke. However, there are treatments available that can help people manage this disorder and slow its progression over time. By working closely with a medical team and making lifestyle changes to support kidney health, it is possible for people living with PKD to have long and healthy lives.

Urinary tract infection

A urinary tract infection (UTI) is an infection that can occur in any part of the urinary system, including the kidneys, ureters, bladder, or urethra. UTIs are most commonly caused by bacteria, but they can also be caused by fungi or viruses. Symptoms of a UTI may include pain or burning during urination, increased frequency or urgency of urination, cloudy or blood-tinged urine, and pelvic pain. If left untreated, a UTI can lead to serious complications, such as kidney damage or sepsis. Early diagnosis and treatment is essential for preventing serious health problems. UTIs are typically diagnosed through urinalysis, which can detect the presence of bacteria or other organisms in the urine. Treatment usually involves antibiotics to kill the infection-causing bacteria. In some cases, hospitalization may be necessary to treat a severe UTI. Additionally, drinking plenty of fluids and emptying the bladder frequently can help to flush out bacteria and prevent reinfection. Wiping from front to back after using the restroom can also help to reduce the risk of UTI development. Avoiding masturbation devices would good idea if you get frequent urinary tract infections because they can introduce new bacteria into the urethra.

UTI and D-Mannose

A urinary tract infection, or UTI, is a common medical condition that can cause symptoms such as painful urination, abdominal discomfort, and sometimes even fever. While conventional treatments typically involve antibiotics, these medications often come with unwanted side effects like nausea and diarrhea. Fortunately, there is another alternative in the form of D-Mannose, a naturally-occurring sugar that has been shown to help treat UTIs by eliminating bacterial biofilms and relieving symptoms. Unlike antibiotics, which can damage gut health by killing off beneficial bacteria along with the harmful ones, D-Mannose does not disrupt this critical ecosystem. As a result, D-Mannose is becoming an increasingly popular treatment for UTIs, offering an effective and safe alternative to antibiotics.

Kidney stones

Kidney stones are one of the most painful medical conditions to experience. These small, hard deposits form when there is an imbalance in the levels of certain minerals in the body. As they grow larger, kidney stones can cause severe pain as they move through the urinary tract. Treatment typically involves drinking plenty of fluids and taking pain medication. In some cases, surgery may be necessary to remove the kidney stone. Prevention is the best way to avoid kidney stones, and maintaining a healthy diet and lifestyle is the best way to do this. Drinking plenty of fluids, especially water, and eating a diet high in fiber can help to prevent kidney stones from forming.

Glomerulonephritis

Glomerulonephritis is a serious kidney condition that occurs when the tiny filtration units in the kidneys, known as glomeruli, become inflamed and damaged. This can disrupt normal kidney function, causing a buildup of waste products in the bloodstream, resulting in numerous symptoms such as swelling and joint pain. While there is no cure for glomerulonephritis, treatment options can help to reduce inflammation and manage symptoms. These may include medications to control blood pressure or reduce harmful inflammatory chemicals, along with lifestyle changes to support overall kidney health. With proper medical care and close monitoring, many people with glomerulonephritis are able to live healthy lives despite this chronic condition.

Kidney disease is a serious condition that can lead to a variety of health problems. If you have kidney disease, it is important to monitor your symptoms and seek medical treatment as soon as possible. There is no one-size-fits-all approach to managing kidney disease, but by working with your healthcare team and following their recommendations, you can help improve your health and quality of life. Remember, knowledge is power, so be sure to educate yourself about kidney disease and its treatment options. With the right information and support, you can live a full and productive life despite this serious condition.

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Date: April 29, 2022 12:41 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Delta-8 THC Shows Promise in Combating Myocarditis

Heart disease is the leading cause of death in America, and myocarditis is one of the most common causes. Researchers are constantly looking for new ways to combat this deadly disease, and Delta-8 THC may be a promising treatment. A recent study found that Delta-8 was able to slow down heart rate and reduce inflammation in mice with myocarditis. While more research is needed, these findings suggest that Delta-8 could be a valuable tool in the fight against heart disease.

What is myocarditis and what are the symptoms?

Myocarditis is a term used to describe inflammation of the heart muscle. This can occur for a variety of reasons, including infection or injury, and it can cause a wide range of symptoms. Some of the most common signs of myocarditis include shortness of breath, chest pain, and chest tightness. Other possible symptoms include dizziness, lightheadedness, fatigue, nausea, and weakness. If you experience any combination of these symptoms along with changes in your heart rate or blood pressure, it is important to seek immediate medical attention to determine whether you are suffering from myocarditis. Treatment will depend on the specific cause of your condition, but it typically involves anti-inflammatory medications and rest. Early diagnosis and treatment are essential for preventing the progression of the disease and reducing the risk of cardiovascular complications.

What causes myocarditis and how is it diagnosed?

Myocarditis is a condition characterized by inflammation and swelling of the heart muscle. This can lead to a number of symptoms, such as shortness of breath, chest pain, increased heart rate, and cough. There are many possible causes of myocarditis, including infections, autoimmune disorders, metabolic or nutritional disorders, or exposure to toxins or other irritants. In order to diagnose myocarditis properly, doctors will typically perform several different tests. These may include blood tests, scans of the heart using ultrasound or MRI technology, and electrocardiograms to assess heart activity. Ultimately, the treatment for myocarditis will depend on its underlying cause and the severity of symptoms. With proper care, however, most people can recover fully from this condition.

How is myocarditis treated and what are the potential complications?

Myocarditis is a condition that occurs when the heart muscle becomes inflamed. This can be caused by a viral infection, an autoimmune reaction, or other factors. Treatment for myocarditis generally involves addressing the underlying cause, if possible. For example, if the inflammation is due to a viral infection, antiviral medications may be prescribed. Corticosteroids may also be used to reduce inflammation. In some cases, heart surgery may be necessary to repair damage to the heart muscle. Complications of myocarditis can include heart failure and arrhythmias. With prompt and appropriate treatment, however, most people with myocarditis recover fully.

What is Delta-8 THC and how does it work?

Delta-8 THC is a chemical compound that is found in the Hemp plant. Unlike other forms of THC, which produce psychoactive effects by binding to cannabinoid receptors in the brain, Delta-8 simply activates these receptors without producing any noticeable effects on cognition or perception. While the precise mechanism of action for this compound remains somewhat unclear, scientists believe that Delta-8 works by interacting with specific neuroreceptors in the brain and body, thereby triggering a series of responses that ultimately lead to changes in mood or behavior. Furthermore, research suggests thatDelta-8 may also have antioxidant properties and may be effective at reducing inflammation in certain tissues. Overall, while more research is needed to fully understand the pharmacological effects of this compound, it seems clear that Delta-8 has great potential as a therapeutic agent and may hold benefits for patients suffering from certain mood disorders or neurological conditions.

Delta-8, inflammation and relaxation

Delta-8 is a cannabinoid that is found in hemp plants. This compound has a similar structure to Delta-9 THC, the main psychoactive compound in cannabis. However, Delta-8 is much less potent than Delta-9 and does not produce the same psychoactive effects. Instead, Delta-8 provides a more mild physical response that is associated with relaxation and relief from anxiety and pain. Research suggests that Delta-8 may also be effective in reducing inflammation. This anti-inflammatory effect may be due to the ability of Delta-8 to bind to CB2 receptors, which are found in high numbers in the immune system. As a result,Delta-8 may offer a unique combination of anti-inflammatory and relaxant effects.

What are the findings:

The results of recent studies suggest that delta-8, a type of cannabinoid found in cannabis plants, may play a role in reducing the symptoms of myocarditis. Myocarditis is a condition characterized by inflammation and damage to the heart muscle, which can lead to serious complications such as cardiac arrest if left untreated. Early research has shown that delta-8 may be able to help protect against this deterioration, as it was found to reduce levels of oxidative stress and inhibit pro-inflammatory signaling pathways. As more studies continue to explore the mechanisms underlying myocarditis, it is hoped that delta-8 will become an important tool for managing this deadly disease.

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Date: April 28, 2022 04:19 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What Cellular Mitochondria Does in the Body

If you want to stay healthy, it's important that you know what cellular mitochondria does in the body. Mitochondria are organelles found in the cytoplasm of cells. They are responsible for producing energy for the cell. Without them, the cell would not be able to function properly. We will discuss the role of mitochondria in the body, and how they impact our health.

What are mitochondria and what do they do in the body

Mitochondria are organelles that play an important role in the energy metabolism of cells. Most of the oxygen we breathe is used by mitochondria to convert glucose from the food we eat into ATP, the energy molecule used by our cells. Therefore, mitochondria are often referred to as the "powerhouses" of the cell. In addition to producing ATP, mitochondria also have other important functions, such as regulating cell growth and death, as well as calcium homeostasis. Mitochondria are unique in that they have their own DNA separate from the DNA in the cell nucleus. This mitochondrial DNA is passed down from mother to child, which is why defects in mitochondrial function can lead to diseases that are inherited in a maternal lineage. Although most of our cells contain only a single nucleus, they may contain hundreds or even thousands of mitochondria. This allows them to produce enough ATP to meet the energy needs of the cell.

How mitochondrial dysfunction can lead to health problems

Mitochondria are integral to many essential physiological processes in the body. Not only do they produce energy for cells, but they also play a key role in maintaining cellular structures and initiating cell division. Therefore, any disruption of normal mitochondrial function can have far-reaching consequences for overall health and well-being. Maladaptive responses to environmental stressors, such as chemical exposure or radiation, are among the most common causes of mitochondrial dysfunction. These stressors result in damage to mitochondrial DNA and can cause problems with cell division and abnormal growth patterns, which can lead to a range of disorders and chronic diseases. For example, mitochondrial dysfunction has been linked to conditions like Alzheimer's disease and type 2 diabetes, as well as cardiovascular disease and cancer. Therefore, it is important to understand the role that mitochondria play in maintaining healthy functioning bodies and take proactive steps to prevent or reverse damage from maladaptive responses to environmental stressors.

Mitochondria and Longevity

Mitochondria are specialized organelles found within our cells that perform many critical functions, including generating energy to support cellular processes and maintaining healthy cell function. These organelles are the site of many important chemical reactions, often referred to as oxidative phosphorylation or metabolism. Studies have shown that Proper functioning of these organelles is essential for healthy aging, and may be a key factor in determining how long we live. By promoting mitochondria health and making lifestyle changes that help to promote healthy mitochondria, we can take an important step towards optimizing our longevity potential. This includes eating a nutrient-rich diet with a focus on foods high in antioxidants, managing stress levels through regular exercise and relaxation techniques, and avoiding environmental toxins that can damage mitochondria health. Through such strategies, we can give ourselves the best chance at living a long, full life.

Ways to protect your mitochondria and keep them healthy with PQQ

PQQ, or pyrroloquinoline quinone, is an important molecule for the functioning of mitochondria in the human body. This compound plays a crucial role in adenosine triphosphate (ATP) synthesis, the fundamental energy currency of biological systems. By driving cellular processes that release energy for metabolic use, PQQ plays a key role in maintaining mitochondrial health and efficiency. Additionally, PQQ has been shown to exhibit powerful antioxidant properties, which help to mitigate the effects of oxidative stress on mitochondria and other critical cells in the body. Overall, PQQ is an essential component of healthy mitochondrial function and a crucial nutrient for energy production and overall metabolic health.

D-ribose, the Mitochondria, and Energy

D-ribose is a naturally occurring sugar that plays an important role in cellular metabolism and energy production. This nutrient is especially important for cells that rely on a lot of energy, such as those found in the heart and muscles. D-ribose helps these cells to generate adenosine triphosphate, or ATP, which is the main energy currency used by cells to drive chemical reactions. Additionally, research has suggested that d-ribose can help to improve physical endurance and reduce the pain and stiffness associated with exercise, making it an important part of a healthy, active lifestyle.

Also, D-ribose is a simple sugar that plays an important role in the structure and function of mitochondria, the powerhouses of the cell. In addition to supplying energy to the cells, mitochondria also help to regulate cell growth and death. D-ribose is essential for the proper function of mitochondria, and it plays a key role in energy production. Studies have shown that D-ribose can help to improve mitochondrial function and reduce fatigue. In addition, D-ribose supplements have been shown to improve exercise performance and increase energy levels. These effects are likely due to the ability of D-ribose to help the body produce more ATP, the energy currency of the cell. For these reasons, D-ribose is an important nutrient for maintaining healthy mitochondria and supporting cellular energy production.

Another important nutrient for the mitochondria is CoQ10

The process of producing energy is called oxidative phosphorylation, and it involves the transfer of electrons from nutrients to oxygen. This reaction creates a proton gradient across the mitochondrial membrane, which is used to generate ATP, the energy currency of the cell. Coenzyme Q10 (CoQ10) is an important component of this process. It acts as an electron carrier, shuttling electrons between enzymes in the respiratory chain. It also helps to maintain the proton gradient, allowing the mitochondria to continue generating ATP. Without CoQ10, oxidative phosphorylation would grind to a halt, and cells would quickly run out of energy. Consequently, CoQ10 plays a vital role in energy production and cellular metabolism.

The bottom line is that both D-ribose and CoQ10 are important nutrients the body needs to maintain optimal energy levels. If you’re feeling run down, low on energy, or just generally not your best, consider taking a supplement containing these two nutrients. You may be surprised at how much better you feel once you start including them in your diet. What’s stopping you from giving them a try?

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Date: September 01, 2020 11:03 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Curcumin and Grapeseed

Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society.

Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone.

Two top suggested natural medicines available right now are curcumin and grape seed extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and grape seed extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous.

Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation.

Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells.

Curcumin Must Be Absorbed To Be Useful

One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil.

Curcumin Makes Chemo More Effective

There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells.

Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news!

Curcumin Protects The Body During Cancer Treatment

In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective.

The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement.

At the end of the treatment which lasted 20 weeks the most dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.

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Date: May 14, 2019 05:01 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Sweet dreams: Eating honey before you go to bed can help you sleepbetter

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Date: May 13, 2019 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why astragalus is good for your nervous system

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Date: May 02, 2019 12:01 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Potassium and Pregnancy: Everything You Need to Know

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Date: October 12, 2018 07:52 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Relieve muscle spasms naturally with the pomegranate

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Date: June 20, 2018 04:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD may help smokers quit cigarettes, finds new study

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Date: February 21, 2018 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 Signs You're Not Getting Enough Potassium and How To Overcome It

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Date: June 26, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Egg White Nutrition Benefits the Skin, Heart, Muscles & More

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Date: May 20, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Drink This To Get Rid Of Your Migraine

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Date: March 12, 2017 06:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Top 20 Foods with electrolytes

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Date: March 04, 2017 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How antioxidants aid in healthy living: Vitamins C, E and beta carotene can help ward off a ...

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Date: February 07, 2017 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Top 5 Selenium Foods to Fight Selenium Deficiency

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Date: January 08, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Conversation US: 13 ways to keep free radicals away, and why it's so important

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Date: January 04, 2017 10:37 PM
Author: Darrell Miller
Subject: Antioxidants- How To Fight With The Free Radicals

Free radicals are of good concern to any individual who wants to stay healthy. You have possibly heard of how hazardous these substances are and how essential are antioxidants that battle them. Understanding free radicals involves mastering just a little bit about their chemical background. Your body is made up of numerous connected parts. The organs and tissues that form these parts are all made from cells. In original terms, each cell is an independent unit that processes its waste and ingests nutrients, additionally to performing several other functions.

The Chemistry That Drives Our Cells

Chemical Reactions: All About Charge

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Date: November 10, 2016 05:53 PM
Author: Darrell Miller
Subject: Always Tired? Burnout and Adrenal Fatigue Solutions

Do you often feel run down and fatigued during the day? So tired you could sleep? Do you crave and use salty and sweet foods as well as caffeine to get you through the day?

If you answered yes to one or more of these questions it is likely that you may be suffering from Adrenal Fatigue or "Burnout." It's a very common problem which often goes unnoticed. It affects significantly more women than men. The number of people suffering has rocketed since the recession - money worries and job worries causing major stress.

What is Adrenal Fatigue?

Adrenal Fatigue is a term used to describe when the adrenal glands are exhausted. Adrenal fatigue is very commonly associated with stress levels. The adrenal glands release Cortisol in response to all stress, cortisol is your natural anti-inflammatory and reduces stress and inflammation levels when needed.

Your adrenal glands are located just above the kidneys and are the size of walnuts. They have a very important function within the body, they secrete over 50 different hormones which your body needs to survive. As well as cortisol some of the other hormones that the adrenal glands secrete include testosterone, estrogen, epinephrine, and progesterone.

People can live with this all their life and think it is just normal. This fatigue cannot simply be relieved by a good night's sleep. An estimated 80% of people at some point experience some form of adrenal fatigue and the physical symptoms associated with stress.

It is unlikely that a doctor will immediately diagnose you with adrenal fatigue, in my research I read about a female sufferer of adrenal fatigue who saw 27 different doctors before having her problem identified as adrenal fatigue! This is an extreme case.

Symptoms and negatives effects of adrenal fatigue

Adrenal fatigue can really wreck the life you live, in extreme cases, it can be so bad that you are only able to stay awake and move around for a couple of hours a day. Changes are made in your carbohydrate, protein and fat metabolism, fluid and electrolyte balance is affected as well as your heart, cardiovascular system and sex drive as a result of adrenal fatigue.

The main symptoms of adrenal fatigue are:

• You feel unusually tired a lot of the time 
• You feel run down and have no energy
• You struggle to wake in the mornings despite what time you went to bed the night before 
• You struggle for energy in the afternoon 
• It is only really about 10am when you wake up properly despite being up for several hours 
• 'Wake up' again after around 6pm 
• Illness and stress hit you hard and you struggle to get rid of it 
• You have cravings for sweets, salty snacks and caffeine 
• Increased PMS or menopausal symptoms 
• Slight depression 
• You feel weak a lot of the time, tired and weak at the top of stairs 
• Low sex drive 
• Increased allergies 
• Dizziness and feeling light-headed after standing up

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Date: September 21, 2016 02:47 PM
Author: Darrell Miller
Subject: The Ultimate Solution To Stomach Pains

The Omega-7 fatty acids, also known as Palmitoleic acid, are unsaturated fatty acids found in sea Buckthorn berry oils. Though not popular among many people, Omega-7 fats are miraculously beneficial to your health, especially the stomach.  Buckthorn plant and your health:

Health conditions related to the human digestive system

The human digestive system which lies in the center of the body spans over 100sq meters; right from the mouth to the anus. It’s specifically known for its vital role in the absorption of water, nutrients, and electrolytes necessary for maintaining life. Additionally, it’s crucial in barring pathogens, toxins, and allergens from harming the body. Recent studies have also shown that the gastrointestinal tract helps in immunity, cholesterol metabolism, detoxification, and emotional balance.

Unfortunately over 65 million people around the world are suffering from digestive related illnesses like ulcers, Crohn’s disease, irritable bowel syndrome (IBS), and gastro esophageal reflux disease (GERD). All these diseases share a common feature; inflammation and damage of the mucous membranes.

If you are one such person,  Omega-7 is your solution.

Omega-7 and the Gastrointestinal Tract

The Omega-7 fatty acids are well-known for their ability to nourish and lubricate the mucous membranes in the digestive tract.  Omega-7 has anti-inflammatory properties that can ease intestinal aches and pains. 

Besides treating digestive related conditions, Omega-7 has been found to help in;

• o Weight management,
• o Skin, hair and nail treatment, and
• o Cardiovascular treatment

Reference URLs

//omega7.biz/omega-7-benefits/omega-7-soothes-the-gastro-intestinal-tract

//www.seabuckthorninsider.com/omega-7/sea-buckthorn-omega-7/

//www.seabuckwonders.com/education/omega-7-health-benefits/

//www.lifeextension.com/Magazine/2014/4/Omega-7-Protects-Against-Metabolic-Syndrome/Page-01

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Date: August 16, 2015 07:14 PM
Author: Darrell Miller
Subject: What is the Krebs cycle and why is it important?

The Krebs cycle is a series of chemical response that helps in the production of Adenosine triphosphate (ATP) and carbon dioxide, a compound that is rich in energy.  This cycle happens with the combination of two carbon coenzymes and carbon complexes and goes through a series of changes to produce the required energy that is needed for the smooth functioning of living organism.  This cycle occurs in all the cells that use oxygen for their respiration process.  Carbon dioxide has an important role since it fuels breathing and the ATP also plays a vital role as it provides cells with a required energy for synthesis of proteins from amino acid and the reproduction of deoxyribonucleic acid.  These are considered essential for energy supply and for the continuation of any kind of life including human.

The Krebs cycle is known as the second phase of the aerobic respiration.  Aerobic respiration is composed of three phases, Glycosis is the first phase, followed by the Krebs Cycle, and last is the electron phase.  These three stages are a series of a cycle that all living cells must experience to produce the required energy for the smooth functioning of the mechanism of life.

Why Krebs cycle is important?

Poor digestion, fatigue and lack of proper nutrition are the common complaints among the people of all ages all over the world.  This complaint comes when the body does not get proper nutrition or is unable to digest food even if it's available.  It leads to a chronic problem and makes most of the people suffer. But what makes them suffer? This is the listless metabolism that ultimately leads to slow Krebs cycle function. When Krebs cycle does not function properly, after a period of time it causes the accretion of undigested food remains in the blood vessels and also creates some other health complications such as constipation, fatigue and smoggy brain.  In the long run, it can create some other health complication that is severe and sometimes life-threatening. So to avoid this situation people usually prefer to take the Krebs cycle supplement.  This supplement resolves all these issues and also makes you feel energetic.

Why your body is reliant on Krebs cycles?

Krebs cycles are important since it helps to generate energy from the food, particularly from the carbohydrate. And you can get carbohydrate from grains, cereals, fats and also from vegetable and animal sources. You can also get carbohydrates from the proteins.

By definition, carbohydrates are the combination of three important things, carbon, hydrogen and oxygen and these things can be changed to glucose inside your body. Initially your body uses the carbohydrate as the foundation of glucose and then through a series of processing, the body gets the required amount of carbohydrates from the diet. And here Krebs cycle plays an important role to generate energy from the carbohydrate.

The Krebs cycle is considered important for producing energy, it does not help you to run fast and to be active only, and it also enables your metabolic process to work efficiently.

References:

//www.wisegeek.org/what-is-the-krebs-cycle.htm

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Date: July 23, 2014 08:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Vitamins Help Fight Leg Muscle Cramps?

Muscle cramps

1. //www.livestrong.com/article/417443-vitamins-minerals-for-leg-cramps/
2. //www.webmd.com/vitamins-supplements/condition-1399-Muscle+cramps.aspx

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Date: November 28, 2013 04:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Health Benefits Of Barley Grass.

What is Barley

Barley are grains whose grass is used to extract juice that have nutritional supplements, producing abundance of minerals including vitamins to the body. At the point of maturity, grass barley has very essential nutrients such as vitamins, proteins, amino acids and other body mineral supplements. These abundant nutritional elements play a crucial role for optimum health conditions both in children and adults.

Benefits of Barley

The supplements found from grass of mature barley contains significant portion of dietary fiber. This presence of fiber in ant diet plays huge importance in the digestion process and proper absorption of nutrients in the process. In addition fiber prevents any intestinal complication such as colon cancer.

Barley grass acts as a source of protein for our bodies. Proteins play a major role in cell development and their maintenance, leading to the growth of tissues and muscles. This contributes to the overall functioning of all the body organs.

Antioxidant presence in barley grass provides protection and elimination of harmful free radicals in the blood system. These toxic elements can lead to development of infections like cancer, in deficiency of such antioxidants.

Grass from barley has of fair amounts of potassium and calcium. These mineral supplements can be lost from an illness or a heavy exercise, hence the need for replenishment. Calcium- enriched barley grass helps to add these essential electrolytes for optimum body functioning.

Barley grass contains high organic sodium contents, which dissolves calcium deposits in the joints and replenish organic sodium found in the stomach lining. This aids the digestion process by improving hydrochloric acid production in the stomach. People with arthritis conditions can use barley grass juice due to its high content of organic sodium present.

Finally, users of barley grass find it very useful in aiding weight loss, healing of ulcers, correction of blood sugar problems and mostly as a general tonic.

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Date: November 06, 2013 08:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Ubiquinol Get Absorbed Better Than Regular CoQ10

 Benefits is Ubiquinol

Ubiquinol can be described as reduced form of CoQ10 (Ubiquinone). For an individual to benefit from the type of nutrient that is needed for producing cellular energy and reduce signs of aging, the body has to convert ubiquinone to ubiquinol. Studies have shown that it gets absorbed better than CoQ10. It is also known to reduce exercise induced fatigue by around 90% when compared with Ubiquinone. This is probably because CoQ10 has a chemical nature that undergoes “redox chemistry”. This implies that it flips back and forth between not having and having two additional electrons.

Importance of Ubiquinol to Human Body

This is a very important part of the human body because it transports flow of electrons that permits chemical energy to be harnessed down a gradient. This is normally the last stage where food is converted to energy to fuel the body. Ubiquinol on the other hand is the form where these extra electrons are reduced when speaking in chemistry terms. Although there is a small difference between the two, it really has big implications as this is exactly what makes it to be more absorbable in the intestines. In addition to this, the body prefers this form to perform the transport function of the blood. 

It is important to note that Ubiquinol was introduced to the market when Kaneka discovered techniques on how to stabilize the ingredient in 2006. From then, it has become an ingredient in numerous products. Various findings also show that it is the preferred form when it comes to ingestion. There are some studies that also show that this form is beneficial for patients who are suffering from advanced stage cardiac disorders. This is because it is absorbed much easily and also shows potential for greater clinical benefit. Manufactures are also looking into new and more advanced methods that will be used to make sure that it can be absorbed more easily than before.

References:

1. //www.naturalproductsinsider.com/articles/2013/03/coq10-vs-ubiquinol.aspx
2. //www.lef.org/magazine/mag2007/ss2007_report_coq10_01.htm
3. //products.mercola.com/coq10-ubiquinol/

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Date: August 23, 2013 02:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Ubiquinol?

Coenzyme Q10 (Co10) is a naturally-occurring chemical compound in the body which fuels cell growth and enhances enzyme functions. It exists in three forms; ubiquinone (fully oxidized), semiquinone (partially reduced), and ubiquinol (fully reduced). So, ubiquinol is basically a reduced form of Co10, it is a strong antioxidant that can neutralize free radicals. Free radicals refer to a reactive and unstable atom that can trigger many medical conditions such as cardiovascular issues, weak immunity and even cancer.

Ubiquinol is found in almost every organ, tissue and cell in mammals. This lipid-soluble benzoquinol can be acquired through supplementation, biosynthesis and from diet (in small amounts). Ubiquinol plays an integral role in transferring electrons within the body, thereby leading to ATP synthesis. The antioxidant property of ubiquinol is very essential in the functioning of the cellular systems.

Ubiquinone is naturally converted into ubiquinol by the body to produce energy for the cells. The failure of this process can lead to insufficient energy levels in the body. The ability of the body to generate Coenzyme Q10 reduces with age and so does the ability to convert ubiquinone into ubiquinol. Therefore, older people should use ubiquinol supplements to boost their energy levels. Apart from older people, those who suffer from neurological, cardiovascular, diabetes and liver conditions may also have low ubiquinol levels.

There are many health benefits associated with ubiquinol. First, it offers a sufficient amount of energy which the heart needs to work well. It's also a strong antioxidant that protects the heart, and other vital body organs from free radicals. When it comes to energy, ubiquinol is an essential component in 95 percent of the energy produced in the body. Daily intake of ubiquinol supplement can help reduce fatigue and muscle pains; the common symptoms of insufficient Coenzyme Q10 in the body. Since ubiquinol is a strong fat soluble antioxidant, it can protect the body from oxidation, thereby providing an anti-aging benefit.

Do you feel fatigued, run down with no energy?  Consider Ubiquinol as a natural safe energy boosting supplement.

References

1. //en.wikipedia.org/wiki/Ubiquinol
2. //products.mercola.com/coq10-ubiquinol/
3. //www.kanekaqh.com/benefits-of-ubiquinol.html

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Date: March 26, 2013 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CoQ10: What You Ought to Know about This Substance?

Coenzyme Q10 or simply CoQ10 is a substance naturally present not only in a human's body but as well as with the other mammals. It plays a vital role in the production of energy. Back in the year 1957, Dr. Frederick Crane successfully used the mitochondria from the cells of a beef heart in order to locate Coenzyme Q10. But the truth of the matter is that, the substance is also present in human mitochondria. Basically, this substance has antioxidant properties which are highly beneficial in protecting the body against the free radicals present in the environment. Below are some relevant details you ought to know about this substance.

Here they are:

CoQ10 in Kreb's Cycle

There are a number of chemicals that the body needs to induce metabolism and one of those chemicals is CoQ10. The Kerb's Cycle is the body's mechanism to convert certain enzymes into energy. In order to achieve that, the body needs CoQ10 to facilitate the conversion of the enzymes in energy production. CoQ10 is fundamental in the Kerb's Cycle as it supports the electron transport chain in which the oxidative phosphorylation of the ADP (adenosine diphosphate) into ATP (andenosine triphosphate) needs electrons that are exactly delivered where they must be. Without CoQ10, the entire Kerb's Cycle process would certainly fail. The mitochondria of every power cells synthesize CoQ10 so the substance is present in almost all the body parts. However, the heart consumes the most CoQ10 for the reason that it has the most number of mitochondria and it keeps on working even while the body is at rest.

CoQ10 Deficiency

If the Kerb's Cycle fails due to CoQ10 deficiency, the person will feel exhausted and weak. But aside from that, there are other conditions that are often associated with the deficiency such as cardiovascular related diseases, Parkinson's disease and gum disease. Conversely, it doesn't necessarily mean that those diseases are brought about by CoQ10 deficiency.

CoQ10 Dietary Sources

The main sources of CoQ10 include fish oil, whole grains and organ meats. With a balance diet, people can get sufficient amount of coenzyme Q10.

CoQ10 Supplements

Aging is an inevitable process and it can affect the synthesis of CoQ10. As humans grow older, the production of the coenzyme Q10 gradually decreases. It was mentioned earlier some of the foods that are incredibly beneficial in maintaining ample amount of CoQ10 in the body. But people who do not really include those foods in their diet should not worry for there are now food supplements that contain CoQ10.  Some medications like cholesterol meds can prevent the body from using CoQ10, this is when it is essential for one to take a supplement.

Fortunately, with the advent of medical researches and innovative technology in drug manufacturing, CoQ10 can now be ingested into one single tablet, soft gel capsule, hard shell capsule or an oral spray. CoQ10 is a fat-soluble substance so taking it along with foods is highly encouraged.

Who Takes CoQ10 Supplement?

Children under 18 years old are not allowed to take CoQ10 supplements unless prescribed by the doctor. For adults at the age of 19 or older, the recommended dosage in 30 - 600 mg daily. Higher dosage may be taken for special conditions.

Humans need energy in order to carry out all the tasks. Therefore, CoQ10 must be taken daily, whether from foods or supplements, so the body has the energy to move.

Have you had your CoQ10 Today?

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Date: April 14, 2012 08:03 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Glutathione Good For?

What is Glutathione?

Glutathione (GSH)is a tripeptide derived from non-proteinaceous amino acids. Contains apeptide bond between the group unusual amino of the cysteine group and the carboxylside chain of glutamate. Glutathione, an antioxidant, helps protect cells from reactive species of oxygen such as free radicals and peroxides. Glutathione is nucleophilic at sulfuracceptors and conjugated electrophilic attack poisonous. Groups thiolare maintained in a reduced state to a concentration of about ~ 5 mM in animal cells. Indeed, glutathione reduces any link disulfideformed with in proteins cytoplasmic cysteines by acting as a donor of electrons.In the process, glutathione is converted to its oxidized form glutathione disulfide (GSSG). Glutathione is found almost exclusively in its reduced form, since the enzyme that turns its oxidized form, glutathione reductase,is constitutively active and inducible to oxidative stress.In fact, the ratio of reduced glutathione to oxidized glutathione in cells is often used scientifically as a measure of cellular toxicity. H2O2+ GSSG + 2 ------- 2GSH H2O.

Advantages of the Glutathione

Before discussing the benefits of L-Glutathione, let's first talk a little about the nutrient. Glutathione is an antioxidant enzyme dominant which is soluble in water.It is absorbed mainly in the liver.It helps fight against free radical damage.The free radical damage is harmful relatives. Glutathione is involved in a variety of other functions in the body.

The function of Glutathione - Benefits of Glutathione

Glutathione works in DNA synthesis and repair, protein and prostaglandin synthesis, and amino acid transport.It helps in the metabolism of carcinogens and toxins.Immune system is improved through the use of Glutathione, and contributes to the prevention of cellular oxidative damage, and activation of enzymes. Glutathione also helps and maintains the functions of other antioxidants.

Glutathione deficiency

There is the possibility of a deficiency of glutathione. It usually occurs during aging.For example, it is seen in macular degeneration related to age, diabetes, and lung and gastrointestinal diseases. It may be the cause of pre-eclampsia, Parkinson's, AIDS and other neurodegenerative diseases.

Where to get Glutathione

Some sources of glutathione include fruits such as tomatoes, watermelon, grapefruit, oranges, peaches and cantaloupe.It is found in vegetables such as avocados, potatoes, spinach, okra, acorn squash, and asparagus.It is found in most meats as well. Other sources of vegetables such as broccoli, cabbage, Brussels sprouts, cauliflower, kale, parsley, and not only provide GSH - glutathione peroxidase, but it also stimulates the body to make more BA.Since cooking destroys much of glutathione, you will get more to eat raw or steamed vegetables for the best benefits of Glutathione.

Reduced glutathione is in a supplementation that we personally use a company called source naturals a Natural Product meeting the above requirements.The nutrient content in their signature product - Total Balance.

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Date: November 02, 2011 07:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What does GABA Do in the Brain?

GABA

GABA or Gamma Amino Butyric Acid is a neurotransmitter of the brain. It is considered to be the main inhibitory brain chemical among mammals. In ordinary terms, it significantly regulates the firing of impulses by the neurons. This chemical is naturally produced by the brain and generally acts as a balancer together with other neurotransmitters. This neurotransmitter has a key role in the regulation of nerve excitability all throughout the nervous system. It effectively maintains the equilibrium of the body and the brain in excitation status. Chemically speaking, GABA is classified as an amino acid. However, GABA is not a building block of protein like the other amino acids. This is the reason why in the medical field, GABA is rarely considered as an amino acid.

Moreover, GABA is the prime brain chemical responsible for the regulation of muscle tone among humans. In a disorder called Spastic Diplegia, the absorption of GABA into the muscles is weakened because of damage nervous tissues and cells. This would significantly lead to hypertonic muscles in which the muscles will experience spasms and can not anymore recognize and process the neurotransmitter GABA. On the other hand, GABA in insects acts as both inhibitory and excitatory neurotransmitter.

The Brain

As mentioned above, GABA is an inhibitory neurochemical. It functions at the inhibitory synapses of the brain by attaching to receptor sites in the plasma membrane of both pre – and post – synaptic nerves. Once GABA has bind with the receptor sites, it will cause the ion channels to open and permit either the entry of chloride ion which has a negative charge or exit of potassium ion which has a positive charge. Potassium is the main electrolyte inside the cell. This opening of ion channels will then cause the cell to be either hyperpolarized or re – polarized.

During brain development, GABA also plays a significant role. It significantly controls the proliferation of brain progenitor cells and development of synapses as well as the differentiation and maturation of neurites. Furthermore, GABA is also responsible for the growth and development of embryonic and nerve stem cells. It also activates GABA receptors which lead to the halting of cell cycling in the S – phase. As a result, this will limit the growth of cell thus preventing abnormal growth and even malignancies.

If GABA is in inadequate level, muscle tone is disturbed making it always tensed and the mind will keep on working and working because there is no brain chemical to stop it. Therefore, GABA must be importantly maintained within normal limits.

GABA is naturally produced by nerve cells. However, GABA supplement is now available so that adequate amount of such brain chemical will be administered to the body as needed. GABA supplements can enhance the sleep onset and quality. It can also provide a relaxing feeling and reduce stress and muscle over – activity. Other theories also state that it can regulate mood and behavior thus promoting the total well – being of the person. Ongoing studies are being conducted to show more evidence on GABA’s effect with Human Growth Hormones.

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Date: September 15, 2011 02:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Iodine And Potassium Be Used For Thyroid Health?

Thyroid Hormone Production

The thyroid gland basically is the part of the body that produces thyroid hormones as the its name suggests. It could be found in the neck right around the front area, somewhere around the thyroid cartilage which is more familiar to us as the adam’s apple. The primary function of the thyroid hormone is to regulate and maintain proper metabolism. I addition it also extends its purpose to processes like energy conversion for the body and the body’s processing of other hormones and vitamins to stimulate proper growth and maturation. Commonly when we refer to thyroid disorders, we refer to thyroid production being out of balance. It could either be too high or too low. In the case of overproduction of these hormones an overactive thyroid is usually the culprit and this is called hyperthyroidism. In the case of underproduction caused by an underactive thyroid the disorder is called hypothyroidism.

Thyroid issues also have been noted to be more prevalent in women than in men. The production of these hormones although done actually by the thyroid the process does not start there. The hormone synthesis process which will eventually produce thyroid hormones begin in the part of the brain called the hypothalamus. This is where the TSH or thyroid stimulating hormone is being released from and it then is transported to the thyroid gland via the blood. Then the two thyroid hormones, L-thyroxine or T4, and triidothyronine or T3 are produced. In this process, it is important that regulation occurs and when any disruption happens this is where the imbalances start, either overproduction or underproduction of the hormones occur. A gland known as the pituitary is the key to all this, also located in the brain it can sense how much hormones are in the blood and adjust accordingly to maintain this delicate balance.

Iodine and the Thyroid

Worldwide the most common cause of any thyroid disorder is iodine deficiency. Ample amounts of dietary iodine are needed to produce the thyroid hormones. It is important that we get the correct amount of iodine from our diets, it is so essential that in the US many food products are fortified with iodine and the reason being is that iodine in natural food sources alone are not enough since our food whether it be crops or meat gets its iodine from the soil and our soil is low in iodine content thus the fortification of many of our food products to avoid any thyroid disorders.

Potassium and the Thyroid

Potassium is a very important mineral in the body to maintain good health. It is an important electrolyte and help conduct electricity in the body. In terms of its link with thyroid health, numerous studies have shown that there is an association between low potassium levels and thyroid issues especially hyperthyroidism and in more severe cases it even has been found to be the cause of an overactive thyroid and as such potassium supplementation has been commonly used as treatment to provide relief.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2432)

Date: September 05, 2011 11:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Symptoms Of GABA Deficiency?

Gaba Overview

In this modern age many of our illnesses comes from the lack of certain substances, chemicals or enzymes just to name a few possibilities but the list could go on. They are called so many different things but they all have one thing in common and that’s being essential to our day to day bodily functions. In this writing we will look into possible symptoms of GABA deficiency.

GABA or Gamma aminobutyric Acid

Gamma-aminobutyric acid (GABA) is an essential neurotransmitter in the body. Its main function is as an inhibitor which mainly focuses on regulating neuronal excitability throughout the nervous system and another function that this chemical has it to aid in the regulation of muscle tone in human beings. In terms of its chemical makeup it is essentially an amino acid however it is very seldom to be called that in the scientific community.

The reason mainly for this is because it is not an alpha amino acid and is never incorporated with a protein which what the term amino acid is commonly reserved for in the medical science world. GABA, to keep things simple is mainly essential to the nervous system and brain health. It is responsible for the maintenance of our nervous system functions and some parts of the brain by allowing the nerves to complete the processes needed to get all the necessary chemicals to keep nerve functions healthy.

GABA Deficiency and Symptoms

As a neurotransmitter it has the ability to influence relaxation and aid in preventing anxiety when GABA levels are too low in the body there are a variety of unwanted effects that can happen. The reasons for GABA being too low in the body can possibly be two things, it can either be genetic or acquired reasons. Just to name some specific possible factors in GABA levels being low are chronic stress and chronic pain. Furthermore, inadequate sleep, caffeine excess, excessive electromagnetic radiation and progesterone deficiency may also further initiate the lowering of GABA levels in the body. With GABA being an essential neurotransmitter the first symptom that may arise with a lack of this brain chemical in the body is expectedly anxiety and depression.

Many studies have shown individuals that suffer from some form of anxiety and depression commonly has low levels of GABA in their body and it has also confirmed that when subjects are supplemented with this brain chemical in an attempt to raise levels in the body they are alleviated of the incidence of depression and anxiety. Feeling panicky, nervous and having a low tolerance for stress are also possible symptoms and also have been shown in researches to be alleviated through GABA supplementation. The most common medication for people suffering from these symptoms is valium and as most of us know, even for those who haven’t used it, it has nasty side effects and one of them is addiction to it however more natural means of supplementing with GABA will be able to give the same desired improvements but with lesser side effects.

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Date: May 23, 2011 03:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Stay Young-Looking with PABA

Most people have not heard of PABA, short for para-aminobenzoic acid. It has often been referred as Vitamin Bx and a member of the B vitamin complex, but this is wrong because it is not an essential, nutrient: life can go on satisfactorily without it, so it is not a vitamin.

It is an intermediate in the biosynthesis of folate by bacteria. Since folate cannot be produced naturally by human metabolism it has either to be taken in the diet or synthesized by colonic bacteria such as E. coli using PABA as an intermediate. However, humans can get folate, the natural form of folic acid, from their diet, so PABA is not essential and hence not the vitamin that some claim it to be.

Nevertheless, it is useful, and apart from its application in sunscreens as a UV filter, PABA is a powerful antioxidant and can neutralize the free radicals and free roaming electrons that are believed to be the cause of aging. A supplement of PABA can destroy free radicals as soon as they are generated by your metabolism and atmospheric pollution and prevent the cell damage they cause. It is this cell damage that gives the appearance of aging: wrinkled skin, age or liver spots and a tough leathery appearance. By taking a regular supplement of PABA you can go a long way towards avoiding this and retaining your youthful appearance for a lot longer.

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Date: May 11, 2011 12:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Potassium: Cardiovascular Health, Muscle Function, Cellular Activity, And Blood pH

Potassium is a dietary mineral required in relatively large quantities in comparison with other minerals found in the human diet. It is the most abundant positively charged ion, or cation, in the cytosol, the liquid cytoplasmic matrix found inside all cells of the human body. It has a special relationship with sodium, the major cation outside animal cells. Together they facilitate cellular reformations and intercellular activities, greatly influencing the development of muscles, the brain, and the heart.

electrolytes are solutions of bases or acids that help maintain a healthy pH inside the body. Potassium is an electrolyte absolutely necessary for the upkeep of cells. They enable organic compounds to move charges, which is central to neuronal activities, muscle contraction, and endocrine functions. The presence of potassium is also required to activate the catalytic functions of several enzymes. Some of these enzymes are indispensable in the metabolism of carbohydrates.

Powers Cellular Activities

A cellular phenomenon described as membrane potential affects several types of cells throughout the human body, such as neurons, muscle cells, and endocrine cells. Potassium is involved in this phenomenon, powering countless molecular devices found in the cell membrane much like a battery. It also participates in transmitting signals between cellular organelles, creating an electric current that flows between different parts of the cell.

Intercellular communication that induces the release of neurotransmitters, hormones, and other related organic compounds throughout the body rely on healthy levels of potassium. For example, it allows the beta cells of the pancreas to respond to levels of carbohydrates that get in and out of the systemic circulation, releasing insulin when needed. It fuels a chain of cellular events that lead to many bodily functions.

Promotes Muscle Function

It is not a coincidence that unhealthy levels of potassium lead to bouts of muscle cramps. While involuntary contractions of the skeletal muscles are often associated to older populations, they may afflict people of all ages at any time of the day. More often than not, the underlying cause is malnutrition, especially deficiency in dietary minerals like potassium.

Contractions produced by skeletal muscles are a classic example of physiological functions that necessitate the presence of potassium. When electrical impulses of cell membranes rise and fall at a very fast rate, it results in a cellular event called action potential, igniting a chain of events that lead to muscle contraction. This is the reason why potassium is important in the maintenance of healthy muscles.

Maintains Cardiovascular Health

Potassium is particularly good for the heart. The cardiac muscle is engaged in continuous coordinated contractions that propel blood out of the atria and ventricles to the rest of the cardiovascular system. A condition called hypokalemia, in which the level of potassium in the blood is low, has been linked to abnormal heart rhythms, high blood pressure, and congestive heart failure. Not surprisingly, potassium supplements are used as a therapeutic remedy in the treatment of these diseases.

pH Balance

Potassium has a pH of 14. Taking potassium daily can help you regulate your pH so you can maintain a pH of 7 throughout the day. By maintaining a pH of 7, you can improve your health and reduce the instance of illness.

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Date: May 10, 2011 11:11 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin B2 Is Good for Nutrient Metabolism, Cellular Energy, And More

Vitamin B2 is an essential nutrient. As its name suggests, it belongs to the B complex group of vitamins. The monosaccharide ribose is part of its chemical composition together with the ring moiety called flavin that gives its yellow coloration. Hence, it is also known by the name riboflavin. Inside the human body, it plays a central role in the synthesis of flavoproteins, which are involved in many chemical reactions, especially in the metabolism of other micronutrients and bioactive molecules.

Deficiency in riboflavin is quite common as it is routinely excreted through the urine. Common symptoms include sore throat, seborrheic dermatitis, lower blood count, all of which have been tied to higher incidence of esophageal cancer. Chronic ariboflavinosis, the medical condition caused by vitamin B2 deficiency, has been reported to contribute to carcinogenesis. The good news is that it can be easily reversed with regular intake of foods rich in riboflavin or supplementation.

Aids Nutrient Metabolism

It is not a coincidence that vitamin B2 deficiency is often accompanied by deficiencies in other vitamins and minerals. In some cases, deficiencies may be attributed to impaired liver function or intestinal absorption. That being said, low levels of riboflavin do impact the metabolism of other vitamins, such as vitamin A, vitamin B3, vitamin B6, and vitamin B9, among other water-soluble micronutrients.

Metabolites of riboflavin are required in the conversion of these vitamins to their active forms, for example, from vitamin A to retinoic acid, vitamin B6 to pyridoxic acid, vitamin B9 to folic acid. Furthermore, the metabolism of bioactive compounds, including fats, proteins, and carbohydrates, also necessitates the presence of this vitamin, the reason why it greatly impacts growth and development in children.

Increases Cellular Energy

In addition to its physiological potential in intermediary metabolism, vitamin B2 is also present in the generation of adenosine triphosphate, the primary transport of energy that powers intracellular activities. Adenosine triphosphate is synthesized in three different metabolic pathways, and one process called oxidative phosphorylation necessitates the involvement of flavin adenine dinucleotide, one of the active forms of riboflavin.

Vitamin B2 is an important cofactor in all chemical reactions that result in an increase or decrease of oxidation state. These reactions are collectively called oxidation-reduction, or simply redox. Metabolites of riboflavin are reliable oxidizing agents capable of carrying high-energy electrons needed for oxidative phosphorylation. They also participate in beta oxidation, another metabolic pathway that yields cellular energy.

Scavenges Free Radicals

A nucleic acid derivative of riboflavin is an important constituent of a special class of organic compounds called flavoproteins. These proteins are found in almost all cells of the human body, and one of their functions is to protect the cells from oxidative stress brought on by free radicals. Vitamin B2 is present in the production of cellular energy and the removal of harmful by-products of energy metabolism.

Insufficient intake of vitamin B2 is deleterious to human health, inasmuch as its biological roles are quite pervasive at the molecular level. Do you get enough Vitamin B-2?

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Date: May 07, 2011 11:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Important are Minerals in the Body

Minerals And Your Health.

Minerals are nutrients necessary for human life. They are often found in the foods we eat at dietary quantities. Living a healthy lifestyle always means having the right amounts of minerals in our diet. Each mineral has a daily value, which necessitates its consumption on a regular basis. Not meeting the requirement for a single mineral for extended periods of time will lead to deficiency.

Deficiency in any nutrient will always impact our health. Minerals are especially important because they are very pervasive throughout the human body. They even affect the digestion and absorption of other nutrients. It is common knowledge that long-term deficiency in any mineral will have deleterious effects on human health that may even result in malnutrition and faster progression of diseases.

Quantity Minerals

Dietary minerals are actually chemical elements that are involved in countless chemical reactions in the human body. It is very probable that various tissues and organs will collapse when these elements progressively decrease. Some elements are necessitated in relatively large amounts, and this group of minerals is called quantity elements, which include potassium, chlorine, sodium, calcium, phosphorus, sulfur, and magnesium. Human health is quite sensitive to low levels of these minerals.

Potassium is an electrolyte present in systemic circulation to regulate blood pH. Chlorine is generally obtained from table salt, which is indispensable in the synthesis of gastric acid. Sodium, like potassium, is a systemic electrolyte that also participates in many cellular functions. Calcium is required by almost all tissues, and absolutely necessary for bone health. Phosphorus is involved in the upkeep of several tissues, including bones. Magnesium plays a pivotal role in the metabolism of energy.

Trace Minerals

Trace minerals refer to dietary elements that are needed in, as the name suggests, minute quantities. A significant fraction of the global population has been reported to be deficient in most of these elements in that their intake has been associated with foods that are not consumed on a daily basis. In the past few decades supplementation seems to be the only certain way to obtain healthy levels of trace elements, which include zinc, iron, manganese, copper, iodine, selenium, and molybdenum.

Zinc is necessitated by over a hundred proteins that belong to all classes of enzymes. Iron prevents iron deficiency anemia since it is central to the production of hemoglobin. Manganese binds to proteins and activates their biological roles in enzymatic reactions. Copper and molybdenum participate in the metabolism of oxygen, which occurs in every cell of the body. Iodine is pivotal to the biosynthesis of thyroid hormones, influencing physical growth, mental development, and metabolic rate. Selenium boosts the immune system and improves the antioxidant defense of cells.

The scientific community has estimated the recommended daily allowance for each dietary mineral for good reason. Regular intake of minerals helps ward off diseases and keeps our body in prime condition.

Minerals are essential for life, are you getting enough of them daily?

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Date: February 08, 2011 04:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lycopene is More than Just a Tomato Extract!

Lycopene is a naturally occurring antioxidant, and a very powerful one at that. Like beta-carotene, it is a carotenoid, a phytochemical that gives certain plants their orange or bright red pigmentation. While lycopene belongs to a group of carotenoids called carotene, known precursors of vitamin A, it does not get converted into vitamin A inside the human body, which is not a bad thing, inasmuch as lycopene in itself exhibits antioxidant properties that surpass the effects of vitamins.

Tomatoes are very rich in lycopene, and indeed consumptions of tomatoes have been reported to show the antioxidant properties of lycopene. Papayas, pink guavas, and watermelons are also good sources of this compound, but the plant source identified to have the highest concentrations of lycopene is Gac, in English also known as Sweet Gourd, a bright red fruit native to Southeast Asia and largely unknown to the rest of the world. With that, a significant fraction of the total lycopene consumption worldwide is derived from tomatoes.

Reactive Oxygen Species (ROS)

Chemical reactions in the human body that respond to the presence of oxygen are part of a process called oxidation, which takes place everywhere else in nature. These reactions entail a change in the oxidation number of atoms or molecules involved in the movement of electrons between molecules inside the body, giving rise to toxic by-products collectively known as reactive oxygen species.

When cells produce the energy that they use to power their physiological functions, they also produce reactive oxygen species, or ROS, which is now believed to be a key factor in the progression of physical infirmities associated with the aging process of human beings and other mammals. That being said, ROS are actually in the employ of the immune system, and particularly effective against pathogens, which may be invasive extracellular matter or harmful microorganisms.

Every single cell make use of enzymes that change the chemical makeup of unnecessary ROS, which must always be kept in check as they damage cells even at low amounts. These enzymes outmaneuver the damaging activities of ROS, thereby protecting the cells. In spite of that, the human body is known to produce more ROS as we age or during long-standing exposure to stress.

Lycopene versus ROS

One type of ROS is singlet oxygen, a form of oxygen that is highly reactive to free radicals. In fact, singlet oxygen is a known catalyst of free radicals especially when it gets excited at the molecular level. Lycopene is the best known carotenoid to counter the damaging effects of singlet oxygen in the human body, and reported to have antioxidant properties far superior to vitamin E and glutathione.

The good thing about lycopene is that its bioavailability compounds when exposed to heat, so cooking tomatoes actually brings out the goodness of this chemical compound. Lycopene acts against the proliferation of cancer cells in a number of mechanisms, and, to date, there have been innumerable reports in support of the role of lycopene against most known types of cancer.

Have you had your Lycopene today?

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Date: January 19, 2011 01:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Potassium And Osteoporosis - What They Have In Common!

Potassium is a mineral, in the same column of the Periodic Table as sodium that it resembles. The various solutions of your body are very carefully controlled in the concentration of the electrolytes it contains, and potassium helps to maintain the electrolytic balance in your body cells.

To take an example, menopausal women can tend to secrete calcium and end up suffering osteoporosis, as can older people that are not careful about their diet. That is because most people tend to use too much salt in their diet - salt is sodium chloride, and an excess of sodium over its ideal proportion to potassium can cause loss of certain electrolytes, of which calcium is one.

Simply by increasing the amount of potassium in your diet, you can prevent or even reverse this trend. Potassium and magnesium both help calcium to be incorporated into your bone structure. Vitamin D also helps, but sodium tends to force calcium out. So by maintaining a good level of potassium in your diet you can help to prevent this condition that leads to many problems as you age.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2221)

Date: January 14, 2011 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Potassium: An Overview

Potassium is what is known as an electrolyte: it is a substance that can conduct electricity and is an essential substance in this respect with regard to almost all organs and structures within your body. Your heart function depends on specific electrical impulses that contract the muscles in a very specific fashion.

Potassium and sodium together are largely responsible for these electrical impulses, and much the same holds true for all of the muscular contractions within your body that control skeletal movements, digestion and breathing. That is how important potassium is - without it there would be no mammalian life.

You can get a good supply of potassium from bananas, fish and meat and also from dairy products. However, deficiencies are possible such as in times of illness, particularly of diarrhea and vomiting, and there are also malabsorption conditions such as Crohn's disease, all of which demand a potassium supplement in order to maintain a proper balance between potassium and other electrolytes.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2220)

Date: January 14, 2011 03:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Potassium and Why Do We Need It?

Potassium has a number of roles to play on the stage of human life, not the least of which is to maintain a good balance of electrolytes, and particularly a good balance between sodium and potassium. Excess sodium in your body solutions can be damaging to your health causing, for example, dangerous heart conditions and loss of calcium from your bones leading to osteoporosis.

Other conditions believed to be either caused by or exacerbated by a deficiency in potassium include stroke, inflammatory bowel syndrome (IBS) and high blood pressure. Potassium will not only reduce the possibility of these conditions occurring, but will also offer some unrelated benefits.

Bodybuilders need potassium to increase their muscle bulk, optimize nerve functions and enable the release of energy from carbohydrates, fat and protein to allow them to exercise and burn fat while feeding their muscles with energy and amino acids and also building new muscle tissue.

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Date: January 13, 2011 05:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Krebs Cycle - Our Lifes Blood!

The Krebs Cycle, also known as the Citric Acid Cycle, is an important series of biochemical reactions that are intrinsic to cellular respiration and the generation of energy from oxygen and glucose in aerobic organisms. Although humans can generate energy anaerobically, they cannot do so for long periods and oxygen is essential for life because it fuels the Krebs Cycle. Without this cycle, there would be no available energy to maintain our vital processes.

What is The Krebs Cycle

We shall first discuss exactly what the Krebs Cycle is and then its importance in the body. The process takes place within the mitochondria of the body cells.

A. The cycle begins with the ten-step pathway of glycolysis, during which glucose is converted to two molecules of pyruvate: no oxygen is required for this step. Basically:

Glucose + 2NAD+ + 2P + 2ADP = 2Pyruvate + 2NADH + 2H+ + 2ATP

The pyruvate can then undergo aerobic or anaerobic respiration to generate energy. The Krebs Cycle is the aerobic route, and significantly more efficient that the alternative fermentation.

B. The two pyruvate molecules are then oxidized to two of Acetyl CoA with the release of carbon dioxide. The two acetyl groups of the Acetyl CoA are donated to Oxaloacetate in the presence of water to form Citrate.

C. Citrate then undergoes a number of chemical reactions to arrive back at Oxaloacetate again and the cycle starts all over again by reacting with more Acetyl CoA from Pyruvate and oxygen to form Citrate again. During the cycle more ATP is produced and electrons and other species are sent into the electron Transfer Chain where most energy is generated.

During this cycle three major events occur:

1. During the various transformations of Citrate, specifically when Succinyl-CoA is converted to Succinate, one Guanosine Triphosphate group (GTP) is generated, which then donates a phosphate to Adenosine Diphosphate (ADP) to create the energy molecule Adenosine Triphosphate (ATP).

2. Over the whole cycle, three molecules of Nicotinamide Adenine Dinucleotide (NAD) are reduced to NADH that donates its electrons to the electron transport chain that is responsible for the generation of large quantities of ATP.

3. A molecule of Flavine Adenosine Dinucleotide (FAD) is reduced to FADH2, again donating its electrons to the electron transport system and the generation of energy.

Factor 2 and 3 are of more significance to energy generation than factor 1, and are the major means by which the Krebs Cycle generates energy.

electron Transport Chain

The Krebs Cycle takes place within the mitochondria, structures that are contained in each of your body cells. Also within these mitochondria are a series of membranes that are very important in the generation of energy.

The major energy produced in your body cells comes from the electron Transport Chain, a series of chemical reactions between an electron donor and an electron acceptor. Such reactions drive the transport of hydrogen ions (H+) across the membranes in the mitochondria.

The electron donors are species such as NADH, FADH2 and succinate and the electron acceptors are oxygen molecules. Hence the importance of oxygen in the process of aerobic respiration. The H+ ions are driven across the membranes and result in the conversion of ADP to ATP energy. In essence, the hydrogen atoms and electrons take part in a progressive chain of redox reactions, and at the end react with oxygen molecules and change it to water.

The Ultimate Products

Ultimately, through the whole chain and cycles of:

Glucose to pyruvate (glycolysis) Pyruvate to Acetyl CoA + CO2 (oxidation) Acetyl CoA to Citrate and the entire Krebs Cycle (reduction and oxidation) Krebs Cycle products to the electron Transfer Chain electron Transfer Chain to Water and ATP (redox) Final oxidation of hydrogen atoms to water

Basically: Glucose + Oxygen + 30ADP = Carbon Dioxide + Water + 30ATP

This is not balanced of course, and the ATP could be anything from 29 to 38, though 29.85 is the most accurate calculation to date. The entire process of glycolysis, oxidation, Krebs Cycle and electron Transport Chain is powered by a series of enzymes and a small amount of ATP energy.

Glucose and oxygen are used up as the raw materials and ATP energy molecules are the product. It has been calculated that the total ATP yield obtained from one molecule of glucose lies between 29.5 and 30 molecules of ATP.

The Importance of the Krebs Cycle to Your Body

Were it not for the Krebs Cycle you would not be able to generate energy efficiently from your food. In particular, the carbohydrate content of your food. Carbohydrates are available in your diet from two sources: simple and complex carbohydrate foodstuffs such as cereals and grains, and fats and oils from animal and vegetable sources. They are also available from proteins, which are composed of amino acids at the head of the molecule with a carbohydrate tail.

Carbohydrates by definition contain only carbon, hydrogen and oxygen molecules, and can be converted to glucose within your body. Proteins can be deaminated and then the carbohydrate portion again converted to glucose. In fact, your body will initially use the carbohydrates in your diet as a source of glucose for its glycolysis to pyruvate, then the fatty tissue in your body, then the proteins will be deaminated so your body can get to the carbohydrate they contain.

Were it not for the Krebs Cycle, your body could not use the glucose as described above to generate energy. The only option open to it would be anaerobic respiration, or energy production in the absence of oxygen. ATP is still generated, but much less efficiently.

Anaerobic Respiration

Anaerobic respiration is basically respiration without oxygen. If there was no Krebs Cycle, then this is the only way your body would have to create energy.

Because no oxygen is actually needed for glycolysis or the Krebs Cycle, anaerobic respiration can proceed right to the end of the electron Transport Chain. Then instead of oxygen being used as the terminal electron donor, it has to be another species such as nitrate or sulfate. Because the Reduction Potential of these species is much lower than that of oxygen, the amount of ATP energy produced is also much lower.

Your body tries to compensate by producing even more pyruvate and the excess is removed through lactic acid fermentation. Although this also generates ATP energy enough for short-term use, it leads ultimately to lactic acidosis and a reduction in pH, causing pain and vomiting.

Ultimately, if oxygen is not forthcoming, the brain runs short of the energy needed for it to work and you die. There is insufficient ATP generated from anaerobic respiration to maintain human life.

Conclusion

The Krebs Cycle is of critical importance for the production of energy: not just the energy to enable you to run fast, but to enable your metabolic processes to continue. It is needed for both aerobic and anaerobic respiration, and while lactic acid fermentation can be used by your muscle cells as a brief but effective means of generating short-term energy, it is insufficient to maintain the needs of your metabolism.

Without the Krebs Cycle, mammalian and most other animal life would not be viable and the world would be populated by anaerobic bacteria.

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Date: November 30, 2010 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Free Radicals and how to Combat Them!

Vitamin C and E

Chances are you have heard about antioxidants. They’re everywhere: in the news, on the internet, and, of course, in our body. The first group of antioxidants that spurred the war against free radicals are Vitamin C and Vitamin E. As early as the 15th century, seafarers knowingly consumed citrus fruits in treatment of scurvy, which today we refer to as a disease caused by a deficiency of Vitamin C. On the other hand, intake of green leafy vegetables results in healthy cells in the body, touted lately as one of the benefits of Vitamin E. Since the latter half of the 20th century the term antioxidants have come into wide use, sparking a series of studies that led scientists and health professionals to a much more well-informed understanding of how important these vitamins are to human life.

Antioxidants and Free Radicals

Two things about biochemistry that have been a part of our growing concern about eating right are antioxidants and free radicals, which you might have learned outside the classroom. The human body deploy free radicals for the purpose of killing harmful microorganisms, but somehow these chemical entities get out of control. It should be noted that most known free radicals are short-lived, explaining how we survive as they are toxic to the body. When not properly disposed of, free radicals are one of the reactive oxygen species that create a chain reaction damaging everything, including DNA. The problem arises when the body fails to detoxify these reactive oxygen species, and then the latter run amok inside the body. This is when antioxidants come into the picture.

Vitamin C, Vitamin E, and Peroxyl Radicals

Vitamin C and Vitamin E are lipids that protect the interior of cells from the outside environment and play a role in storing energy for use by the human body. Different groups of lipids encompass several major chemical reactions in the body, including securing the proper functions of physiological communication lines. In a process called lipid peroxidation, peroxyl radicals go on a killing spree by depriving the lipids of electrons, which continues as they bring in more radicals. The human body make use of Vitamin C and Vitamin E to police the proliferation of lipid radicals in time to deactivate lipid radicals and avoid unwanted effects on cell membranes.

Ascorbate and Tocopherol as Co-Antioxidants

In chemical reactions, the body utilizes forms of tocopherol in Vitamin E and ascorbate ions in Vitamin C. These antioxidants work on the principle of pairing with peroxyl radicals, taking on radical forms, ascorbate and tocopherol, to stop the oxidation process initiated by free radicals. At the molecular level, ascorbate makes an ideal antioxidant as it does not react with oxygen and terminates harmful peroxyl radicals that continue to oxidize. Studies say that Vitamin C and Vitamin E are co-antioxidants in that ascorbate works with tocopherol. For example, when continuing oxidation damage lipids, tocopherol, Vitamin E, removes the harmful radicals, and ascorbate recycles Vitamin E back to its usable tocopherol form.

The Perfect Match

Alpha Lipoic Acid recycles both Vitamin C and Vitamin E because alpha lipoic acid is both water and fat soluble.

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Date: July 14, 2010 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glutathion, Antioxidants, And The Body

Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges.

Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis.

A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids.

The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell.

Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion.

Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well.

Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.

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Date: December 10, 2009 04:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE

NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE™

NADH is the biologically-active form of vitamin B-3 (niacin), and is involved in a wide range of functions throughout the body. An easier way to understand it, is to think of NADH as a biological spark plug that makes it possible for us to become and remain energetic, active, and functioning at our best. Remove the “spark” and some of the most basic human functions will inevitably suffer. This is not speculation. It is the result of decades of scientific investigation that has examined the link between nutrition and chronic conditions; notably those related to cellular life cycles and apoptosis, excessive fatigue, enzyme decline, free radical expansion, cognitive disparity, intracellular balance, normalized aging, and many more important aspects of human health.*

Based on a wealth of ongoing studies, we have a great understanding of the benefits of NADH. Not only is it an effective source of cellular energy, it is also one the body’s versatile electron donors—the molecule most frequently degraded during oxidation. Because of these characteristics NADH is, however, also very unstable with regard to light and oxygen, which leads to a very rapid loss of overall effectiveness. Additionally, poor lifestyle choices, such as the use of tobacco, excessive consumption of alcohol, drugs, and prescription medications, sleep deprivation, genetically-engineered foods, and a host of others can all inhibit the activity of NADH within the body. Hope is not lost, however.

NOW® NADH contains a patented form of NADH from Panmol® - the first natural stabilized, stomach acidresistant form of this unique vitamin B3 supplement. Panmol® uses a patented process to naturally preserve its effectiveness. The end result is a highly stable, and bioavailable NADH which can easily withstand the harsh, acidic environment of the stomach and digestive tract; a breakthrough in the battle against many of todays’ most chronic conditions. NOW® NADH is available in both 10 and 20 mg potencies. Both varieties have been further enhanced with 200 mg of Bioenergy RIBOSE™ to support its cellular energy support properties.*

Who Stands to Benefit from NADH

With a proper supply of amino acids and/or B3 vitamins (niacin) the human body is, in fact, capable of producing a limited reserve of NADH. Under chronic strain however, the body’s need for NADH increases. As we age, the body’s ability to manufacture NADH becomes increasingly limited. With this in mind, the following groups stand to benefit the most from incorporating NOW® NADH into their supplement regimen.

• Those who work in stressful, cognitively-demanding professions
• Individuals who frequently struggle with fatigue
• People who have difficultly focusing on routine tasks
• Older and elderly individuals
• Those who want to maintain a high level of mental alertness
• Professionals who travel extensively for business
• Those who experience jet-lag after long flights

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Date: November 05, 2009 01:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Clantro (Coriander Plant) to remove heavy metals

Cilantro Heavy Metal Detox With Chlorella

Planetary Herbals is pleased to introduce Cilantro heavy metal detox, a unique herbal cleansing formula for defense against today’s environmental toxins. The herbs in Cilantro heavy metal detox are known to bind to heavy metals, helping to clear them from the body. Chlorella is added to increase the chelating and cleansing actions of cilantro. This combination also provides effective antioxidant support for overall cell health.

Planetary Herbals Cilantro heavy metal detox contains organic cilantro leaf and organic chlorella, for the purest product possible.

Herbs: Nature’s Answer to a Toxic World

Cilantro (one of the names used for the leaves of the coriander plant, Coriandrum sativum) is an ancient herb that has been used for millennia for health and for its robust, savory taste. Beyond its culinary value, modern research has confirmed the benefits of cilantro as a natural means of internal cleansing.

Recent studies show the cilantro attaches to heavy metals in the bloodstream. This process, known as “Chelation,” helps our bodies eliminate metals from our systems, and helps cleanse and purify our tissues, organs and blood. This process is supported with the addition of chlorella, single celled algae that work synergistically to enhance cilantro’s chelating and cleansing ability.

Binding heavy metals

Thousands of noxious chemical compounds, many of which didn’t exist on the planet 100 years ago, now pervade our food, water, and air. Heavy metals like lead, mercury, arsenic, aluminum, and cadmium enter our bodies through food, air, cooking utensils, deodorant, and even the fillings in our teeth.

Cilantro’s properties that enable binding with these toxins are thought to come from unique constituents, including citric acid, phytic acid, and electrolytes that attach to metals. The sequestration of metal ions by chlorella is assumed to be accomplished by surface ligands in the cell walls. Simply stated, both cilantro and chlorella contain properties that bind with metals, and chlorella additionally helps purge the bound metals from the organs.

Planetary Herbals: the PhytoDynamic Difference

Cilantro heavy metal detox is the latest in a herbal product line based on the principles of PhytoDynamics. PhytoDynamics unites a profound understanding of the interaction between plants and people, a commitment to holistic integrity of herbs for optimal efficacy, a strong grounding in scientific research, a world class quality control team, and a level of clinical expertise unmatched in the industry.

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Date: April 23, 2009 01:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Protect The Liver with Glutathione And Cysteine

The tripeptide L-glutathione is synthesized in the body from L. glutamic acid, L-cysteine and glycine, a reaction that can occur in any cell of the body although it is essential that it also occurs in the liver. Should glutathione concentrations drop, they can be increased by supplementing with cysteine or any other of the three amino acids that are used in the biosynthesis of this important if substance

The tripeptide exists in two forms: the reduced form (GSH) which contains a sulfhydryl (SH) functional group attached to the cysteinyl part of the molecule, and the oxidized form glutathione disulfide (GSSG). As electrons are lost from the reduced form, two molecules combine to create a dimer formed by a disulfide bridge, the process which can be reversed through reduction of the GSSG. Such electrons are lost during its reaction with free radicals, in which the free radicals are neutralized by the donation of an electron from the oxidized version of glutathione.

The definition of a free radical is a molecule that is lacking one electron from an electronic pair. Its prime purpose is then to steal an electron from the nearest molecule to it. In doing so, it can not only destroy that molecule, but also destroy body cells and lead, not only to premature aging, but also to some potentially fatal conditions.

It is an unusual peptide in that it involves a link between the cysteine amino grouping and the carboxyl functional group of the glutamic acid. It is a powerful antioxidant, acting as an effective free radical scavenger and protecting the body cells from the effects of free radical oxidation. However, it is on its detoxification effect in the liver that we shall focus here prior to discussing some other uses to which the body puts glutathione in its two manifestations.

Much of the detoxification is connected with the thiol group in the molecule. Take mercury for example. The thiol grouping forms a strong Hg-sulfydryl chemical bond within the liver, in the form of a glutathione-mercury chelate. In this form mercury is unable to exert any toxic effect on the body and can be excreted in the normal manner. The same reactive pathway is followed by other heavy metals that can bond to thiol groupings. In this way L-glutathione can protect the liver from the effects of a number of toxic heavy metals such as cadmium and chromium.

This is an important property of the amino acid, particularly in industrial and urban environments where the population is more prone to exposure to heavy metals than their rural counterparts. However, the end result on the glutathione is that it is removed from the body, and, particularly with city dwellers, a supplement may be required to maintain a healthy concentration of this amino acid in the body and in particular in the liver. Therefore, although L-glutathione is not considered an essential amino acid, in that it is biosynthesized within the body, a supplement is sometimes required, particularly by those who live in large cities.

It is important to consider the form in which the glutathione supplement is administered. This is because of the presence of gamma-glutamyltranspeptidase within the digestive system. This enzyme appears to destroy L-glutathione before it can be absorbed in the intestine so normal oral forms of supplementation are likely to be ineffective. Possible forms of effective administration include buccal (between the cheek and teeth) and hypodermically.

An alternative means of supplementation is to take substances such as selenium, methionine, alpha-lipoic acid, vitamin C and glutamine that stimulate the biosynthesis of glutathione. Also, since the substance utilizes the raw materials of L-cysteine, glutamic acid and glycine in its intracellular production, supplementation with these amino acids should also help to produce L-glutathione.

That said, let's return to its antioxidant properties and its effect on the liver that contains the largest stocks of glutathione in the body. It is generally regarded as the most important antioxidant in the body. It protects cellular cytoplasm from oxidation by reducing disulfide groups and maintaining a highly reducing environment within the cytoplasm. It reacts with hydrogen peroxide and other oxidative agents, and is converted to the oxidized form GSSG. It is then reduced back to GSH through the combination of the reducing agent and an enzyme. The reducing agent is nicotinamide adenine dinucleotide phosphate (NADPH), the enzyme being glutathione reductase.

The implications that this strong reducing effect has on the liver are significant. Reduced GSH L-glutathione levels have been found in patients suffering from HIV, hepatitis C and other liver diseases. Supplementation with GSH has been found to restore normal levels of glutathione to the liver, and it has been demonstrated that the treatment has improved such conditions significantly.

Atherosclerosis is a condition of the arteries caused by the deposition of plaques formed from oxidized low-density lipoproteins, otherwise known as bad cholesterol. The strong antioxidant effect of GSH prevents this from LDLs from being oxidized and deposited on the arterial wall. There are other results of glutathione supplementation that indicate the effectiveness of antioxidants in the treatment of serious liver conditions, and there are no doubts that combating the effects of free radicals and oxidizing agents within the liver has a positive effect on many potentially serious liver diseases.

Many of these are exacerbated by the generation of free radicals by relatively modern pollution sources such as pesticides, petrol and diesel emissions, tobacco fumes and various other chemical emissions. A strong antioxidant such as L-glutathione cannot be anything other than an effective means of reducing the biological effect of these oxidants. It protects not only the liver but also the lungs and cardiovascular system.

For all these reasons a supplement consisting of L-glutathione or its constituent parts, glutamic acid, cysteine and glycine, provide significant protection against the stresses and strains of modern living. Increased pollution levels and heightened oxidative stress levels within the body are playing havoc with our body defenses, and GSH is an important one of them that can easily be enhanced by supplementation. There are no known reactions to L-glutathione supplementation, but pregnant women and babies should receive expert medical advice prior to taking it.

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Date: April 13, 2009 03:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Detoxify With L-Citrulline

L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood.

It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea.

The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea.

The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-hydroxyarginine, and then into L-citrulline with the release of nitric oxide.

So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells.

Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred.

In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure.

Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery.

During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow.

It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels.

It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid?

Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise.

Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted.

Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.

L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.

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Detoxify At Vitanet ®, LLC

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Date: December 30, 2008 01:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Potassium And Magnesium

Potassium and magnesium are the two most common minerals found within the cells of your body. They each have specific individual functions within your body, and together help to maintain the correct balance of electrolytes and the proper functioning of smooth and striated muscles. That includes allowing muscles to relax properly rather than to cramp.

Before discussing this, let's have a look at the major individual properties of these two metallic minerals with respect to the body's biochemistry.

Magnesium is needed to ensure the proper functioning of the sodium/potassium pump. This is a complex topic, and we shan't dwell on it at length here, although the basics are that it is responsible for the movement of ions into and out of cells. Sodium and potassium ions are moved in opposite directions across the cell plasma membrane, three sodium ions being pumped out for every two potassium ions pumped into the cell.

This is of particular importance to nervous cells responsible for transmitting impulses in response to specific stimuli. In the event of a magnesium deficiency, this pumping action is impaired and the sodium/potassium balance within and without the body cells are imbalanced. This in turn impairs the response of nerve cells to stimuli. Both magnesium and potassium can be depleted through the use of diuretics, in which case a magnesium supplement can redress the imbalance.

There are several consequences of such an electrolytic imbalance, some having potentially serious consequences. Many can cause death if left untreated, although the symptoms usually allow appropriate medical treatment prior to the condition becoming fatal, such treatment frequently involving administration of magnesium and potassium. Among these are:

Calcium overload in certain heart cells that reduces the effective use of oxygen and ATP and causes overactive contraction of the heart muscle.

Spasms in coronary blood vessels.

Over-activity of the striated muscle fibers, leading to cramps in the calf and thigh muscles, for example.

Cramp and pain in the smooth muscles of hollow organs such as the bladder or uterus that can also cause premature labor.

Several heart problems caused by an increase in energy consumption and a calcium overload and potassium deficiency that leads to cardiac ischemia and arrhythmia that continue to create a serious medical condition and hazard to life. Potassium, that can stop the heart if given in excess, can be just as harmful if present in too small a concentration.

The whole situation creates a self-perpetuating cycle that can be broken by a magnesium and potassium supplement that restores the correct gradient of potassium and magnesium across the cell membrane, improves the function of the sodium/potassium pump and reduces the excess cellular calcium by replacing it with magnesium.

This only works if both potassium and magnesium are taken together: just either alone is no good. It also takes time for the effect to occur, so the supplement is not suitable for emergency use. A regular supply can prevent the condition occurring.

There are many other properties that magnesium and potassium possess with regard to the body's biochemistry such as the effect of magnesium in activating certain enzymes. However, in discussing relaxation, both of these essential minerals have a significant part to play.

It has been mentioned that a magnesium and calcium deficiency causes spasms and cramps in the smooth and striated muscles, and the corollary is also true. Magnesium and potassium can be used to relieve such cramps, and relax muscle tissue. Hence, because it can relax excited smooth bronchial muscle tissue, magnesium can be used to relieve asthma attacks. The intravenous administration of magnesium is, in fact, an accepted and proven clinical treatment for acute asthma attacks.

In the same way, magnesium has been used to treat muscle spasms and cramps. Again, it is not an immediate treatment for emergency use, but can be used over a period of days to treat athletes with a history of muscle spasms. Such spasm frequently occur after prolonged periods of exercise, when magnesium and potassium, among other electrolytes, can be lost through a combination of sweating and urination.

However, this is not the only means by which magnesium is lost from your body cells, and probably not even the main one. Less obvious, but likely of more importance, is the transfer of magnesium from the plasma into the red blood cells (erythrocytes). The amount by which this occurs is directly proportional to the more anaerobic the exercise, hence the need by athletes and weightlifters for more magnesium. It can be rapidly lost through exercise with insufficient oxygen, and cause their muscles to cramp up.

Magnesium deficiency is common in Americans, although factors such as high calcium intake, alcohol intake, diuretics, and kidney and liver disease are more responsible for this than a dietary deficiency. Potassium is readily available in bananas, brown rice, potatoes, tomatoes and oranges and dietary deficiencies are not common although supplements are readily available.

Magnesium is also known to play an important part in the secretion and use of insulin by the body. Supplementation with magnesium can help diabetics to make best use of insulin, become more tolerant to glucose and improve the fluidity of the membrane of red blood cells. The mineral; also has a small but definite effect in lowering blood pressure. Other uses for magnesium supplements include congenital heart failure, where higher magnesium contents lead to greater life expectancy and chronic fatigue syndrome (CFS) where magnesium supplements can significantly increase energy levels.

Other uses to which your body puts potassium other than to allow proper muscle contraction and relaxation and to maintain the balance of electrolytes in the body, includes the function of brain and nerve neurons. This, however, is academic since should your potassium levels drop by 50%, death would result.

Potassium, Magnesium and Calcium are essential in maintaining the proper workings of your body cells, although the most visible effect of magnesium and potassium is their relaxation properties on the body, put to specific use by sportsmen and women, particularly those involved in the more anaerobic sports.

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Buy Potassium And Magnesium At Vitanet ®, LLC

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Date: October 22, 2008 04:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Green Coffee Bean Extract

It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs.

The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition.

However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here.

The Free Radical Theory of Aging

Free radicals are oxidants created by unpaired electrons. electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them.

Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging.

Free radicals are generated in the body in four different ways:

1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher.

2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes.

3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting.

4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products.

In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body.

So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell.

Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron.

Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals.

It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol.

The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level.

Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging.

A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life.

There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.

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Date: October 15, 2008 09:46 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GrapeSeed Extract

It is possible to fight off aging with grape seed extract due largely to the antioxidant effect of the phytochemicals contained within the seed of the grape. The seed is rarely absorbed by your body because it is so difficult for your digestive juices to break down; significantly more difficult than the skin or the pulp. So what is specific about the seed that makes it so useful as a source of antioxidants? That shall be discuss shortly, but for now let's discuss the causes of aging, and how antioxidants can help to keep them at bay.

To fight off aging you have to understand what causes it, and the take steps to avoid these causes. It is fairly obvious that all causes of aging cannot be circumvented, but there are things that can be done to keep some of them at bay. Here, we are specifically concerned with the aging of your skin, which is the most visible form of aging. The first aspect of aging to understand is that there are two types: intrinsic and extrinsic.

Intrinsic Aging

Intrinsic aging is natural aging, and is largely genetic. Starting when you are fairly young, normally in the early to mid 20s, intrinsic aging is typified by wrinkling, hair loss or graying of the hair, hollowing of cheeks and other areas where the fat underneath the skin that normally contributes to your physical appearance is lost, and also bone loss that causes your skin to sag due a gradual loss of the structure that sculpts your physical appearance.

The age at which this occurs, and its speed is determined by your genes; although the process generally begins around the mid 20s, the speed with which it progresses is genetically controlled.

Extrinsic Aging

This is where grape seed extract can help. Extrinsic aging is not genetic, but environmental. Ten majority of this type of aging is due to exposure to the damaging UV light of the sun, which cause the typical 'leathery' look of the skin of people raised in areas such locations as the hotter parts of Australia and the USA, without the benefit of the native skin pigmentation that filters out these harmful ultra-violet rays.

Other factors that can cause the same degradation of your skin cells are smoking, the way you sleep and gravity. The sun generates free radicals (more on these later) that can destroy skin cells, cause freckles, leathery skin and a blotched complexion and also skin cancer. Smokers are more likely to develop leathery and wrinkled skin than non-smokers, and as the elasticity of your skin reduces, gravity cause jowls to develop and also a more pronounced lower lip.

Even your sleeping position can make you appear to age quicker, particularly using the same sleeping position on your pillow each night that cause what are known as sleep lines, that are really wrinkles that are difficult, if not impossible to remove. However, one of the most relevant factors is pollution, and the effects of car emissions, pesticides and other agricultural chemicals, paint fumes and 1001 other forms of chemical pollution that produce free radicals.

Where grape seed extract is involved in fighting off aging is in extrinsic aging is by destroying the free radicals. All substances, from the air to the oceans, are formed of atoms that contain electrons. Stable molecules contain an even number of electrons, or what are known as 'electron pairs'. When a molecule loses one electron it is known as a free radical, whose prime purpose in its very short life is to steal an electron from the nearest molecule. This 'short' lifetime can as long as a day or as short as thousandth of a second: it depends on is size and the degree of steric hindrance to the reaction with the spare electron.

Now that the reasons for aging and the nature of free radicals are better understood it is easier for you understand why grape seed extract can help to fight aging caused by the effects of free radicals on your skin.

Grape seed is a waste product of the wine industry. You cannot make wine from grape seeds, so they are removed from the final product by filtration or sedimentation. It contains a large number of phytonutrients, the most important being polyphenols in the form of flavanoids, lipids and carbohydrates. It also contains proteins that don't have much of an effect on aging. Flavonoids (also spelled flavanoids) are powerful antioxidants that destroy free radicals; they are twenty times as powerful as Vitamin E and over fifty times more powerful an antioxidant than Vitamin C.

Both of these vitamins are regarded as strong antioxidants in their own right, which is an indication of how good grape seed extract is at killing free radicals. It's like a combination of Harry Callahan, Paul Kersey, John McClane and the whole of the Magnificent Seven after the scavengers in your body cells. They succeed, and do it in spades!

Not only do the ingredients of grape seed extract kill off free radicals with the efficiency of a Delta Task Force, but are also anti-allergenic, anti-inflammatory, anti-cancer and anti just about anything else you can think of. However, let's have an even closer look and find out exactly what polyphenols are present in this so-called wonder juice.

Procyanadin was originally named Vitamin P in 1936 by its discoverer, Prof. Jacques Masquelier, and is believed to bond with collagen to protect you from premature aging by retaining and even improving the elasticity of your skin. An added benefit is that it also improves the elasticity of your blood vessels, and so helps to fight off the effects of high blood pressure and places less strain on your heart. The overall effect on your face is to practically give you a chemical face lift and also provide protection from the damaging effect of the UV component of sunlight through its lethal attitude towards the free radicals that UV radiation generates.

Another component of grape seed extract particularly that of muscadine grapes is resveratrol; a phytoalexin that has strong anti-inflammatory properties and can also fight off the effects of aging. Phytoalexins are antibiotics produced by plants that are under attack, and, in addition to helping you age slower, confers other benefits to your body including helping your brain to carry out its work more efficiently.

All in all, grape seed extract confers many benefits to your health and is also believed to possess powerful anti-cancer properties. However, it is for its ability to fight off aging that most people use it as a supplement, and in this respect it has been found to be extremely effective. Any antioxidant is of benefit to your body, but grape seed extract is of particular benefit due its high antioxidant potency.


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Date: August 26, 2008 04:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GABA

GABA is gama amino butyric acid, and is an inhibitory neurotransmitter that is essential for the proper function of your brain and the central nervous system, and has the effect of reducing excessive brain activity and promoting a state of calm.

For many people, the rush of daily life, with its problems, worries and external stimuli, can over-stimulate the brain to the extent that it can all seem too much for them. They feel anxious and overwhelmed, and wish that they could just go into a quiet corner to get away from it all. Most people have felt like that at some time, but the demands of life do not allow them that luxury. They just have to bear it and get on with life.

That is where GABA can come in. It can be used to bring your nervous system back to base, and make you feel more relaxed, calmer and more able to meet these challenges that life often throws at you. When you feel that you just can’t relax or concentrate on what you are doing, GABA can help you. If you look around you and everybody else seems OK, without apparently feeling the stress and irritability that you feel, and then perhaps your problem is due to a GABA deficiency. GABA is the principal inhibitory neurotransmitter in your brain, and a deficiency would certainly give you the symptoms that you are feeling. Let me explain why.

As your brain becomes excited, it can run out of control and needs some form of modification or inhibition to keep it acting as normal. Without this you would become increasingly more restless and irritable, and ultimately have seizures. GABA is not only the main inhibitor in your brain, but also helps in the production of endorphins that provide you with a sense of well being. That sense of calm you feel when endorphins are produced, for example during exercise or sexual intercourse, is commonly referred to as the ‘endorphin effect’.

GABA is at its highest concentration in specific areas of the brain, including the hypothalamus, the hippocampus and the central brain area, and is present in up to 40% of all synapses, the small gaps between neurons across which brain cells can communicate with each other.

It is produced during the Krebs or Citric Acid Cycle that is responsible for cell respiration or the production of energy from carbohydrates. It is synthesized from alpha-keto glutarate, which is produced just before the Succinyl Co-A stage of the Krebs Cycle in the brain. Vitamin B6 in involved in its metabolism, and a Vitamin B6 deficiency can lead to a deficiency in GABA that might result in seizures.

Basically GABA works by inhibiting the firing of neurons in your brain, and thus reducing general brain activity. The GABA receptor allows more chloride ion to enter the brain cell, thus helping to maintain the electrical charge within the cells. Bezodiazepines (e.g. diazepam) work by increasing the effectiveness of GABA in opening the chloride ion cells to allow more chloride ion to enter the neurons, and caffeine does the opposite, and inhibits this property of GABA. Thus diazepam works as a minor tranquilizer and caffeine as a stimulant.

Alcohol has a similar effect to the benzodiazepines, increasing the release of chloride into the neurons, and is the major way in which alcohol affects the brain. In fact, tolerance to drugs and withdrawal symptoms can be explained by the receptors adapting to the drug. They may increase in number, which means that more of the drug is needed to work on them, and they can become hypoactive in the event of the drug being withdrawn, that enhances the symptoms that the drug was intended to treat.

So basically, that is the way that GABA works. In simple terms it increases the flow of chloride electrolyte to the brain, and in so doing affects our mood. This effect is enhanced by prescription drugs such as Valium and Ativan, which are used by those that suffer the effects of a GABA deficiency. However, these drugs have side effects, not the least of which is dependency due to the GABA receptors becoming modified to suit the drug. There is a more natural way to overcome many stress problems and symptoms of mood swings.

Knowing what causes these symptoms, it makes sense to eat foods that stimulate the creation of neurotransmitters to replace those that are deficient. Since GABA is produced in the Krebs Cycle and complex carbohydrates produce glutamine that is an important part of that Cycle, and is also the precursor to GABA, then the consumption of such foods should in theory produce more GABA. In this case the theory works, and you should eat foods rich in complex carbohydrates such as whole grains, brown rice and oats as part of your diet.

Other foods that are high in glutamine or its precursors, glutamic acid and glutamate, include citrus fruits, beef liver, broccoli, halibut and lentils. A useful supplement to take is L-theanine, an amino acid found in green tea, and available in supplement form. L-theanine can calm your nerves while maintaining clarity of thought. In other words it calms you down, but doesn’t make you drowsy and allows you to enjoy your day with anxiety.

Your doctor can determine whether or not you have a neurotransmitter deficiency through a simple urine test, and might also test your saliva for hormone content. A GABA supplement might be indicated, and if so it other beneficial effects on your body other than its effect on your brain cells.

It improves your sleep cycles and promotes vivid dreaming, and can also have a positive effect on your blood pressure. It is also an effective pain killer, and can provide relief from such conditions as back pain and arthritis. Its stimulating effect on the anterior pituitary gland to secrete Human Growth Hormone might also be regarded as a benefit by many. Increasing the level of HGH in your blood can lead to fat loss and improved anabolic activity (increase in muscle tissue). This can be of benefit to older people whose level of HGH secretion has dropped off, and who find it more difficult to lose fat.

GABA is a substance that has many known benefits and no known side effects other than a slight tingling and increase in heart rate when the supplement is first used. It has a definite benefit for people to whom the world seems too hectic and overwhelming.

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Date: August 25, 2008 07:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gac Fruit Oil

Most people have never heard of gac fruit, yet it is very popular in South East Asia, particularly in China and Vietnam. The fruit is grown on vines that reach the size of a cantaloupe and from North East Australia across to China and Vietnam it is used as both a food and a medicine. It is only fairly recently that it has found use in the West as a health food

So what’s so special about this fruit, known also as baby jackfruit and sweet gourd? Its bright red color should provide a clue, since it is jam packed full of beta carotene, lycopene and other strong antioxidants that not only helps to support the immune system, but also helps to retard the effects of aging. It has been used in Vietnam in particular to overcome the effects of an endemic deficiency in vitamin A, and is rich in provitamin A carotenoids. It is also widely used in Chinese medicine to treat a variety of complaints.

Antioxidants and Free Radicals

Antioxidants can boost health in a number of ways, and it might help you understand better the benefits that gac fruit can provide to explain what antioxidants do and why they are such an essential part of our diets. Every millisecond of every day of our lives, our natural metabolism of the conversion of blood glucose to energy generates small oxygenated molecules known as free radicals.

Free radicals are molecules that possess an unpaired electron and are highly unstable. electrons generally travel in pairs, and when one of that pair is lost through a chemical reaction, the other electron has only one purpose in its short life: to pair up with another electron and it will do whatever it has to in order to achieve that. It is called a free radical, and its life is short. Free radicals destroy body cells, and this can have a dramatic effect, both visually on your skin, and internally on your general health.

Apart from those generated by your body’s own biochmemistry, free radicals are present in car emissions and other pollutants such as pesticides, smog and fried and barbecued foods. They are also formed in your skin by excessive exposure to the UV component of the sun’s radiation. That is why the skin of those living in hot climates tends to age earlier.

Free radicals are what make you look older as you grow older: they destroy skin cells as they are formed, but that is one of the least of their effects. They can also oxidize low density lipids (LDL) that carry cholesterol around your body, causing it to deposit fatty plaques on the walls of your arteries, which is a serious cardiovascular condition known as atherosclerosis.

Antioxidants can donate an electron to free radicals without then becoming free radicals themselves, and so destroy them as they are formed. However, the antioxidant can then lose its reducing power. Free radicals do not roam the blood seeking victims as many imagine them to, but react almost instantly, as soon as they are formed. It is important, therefore, that antioxidants are present in or close to every cell of your body. To achieve this, they must be bound to a fatty molecule, and the problem with many phytonutrients is that they have no associated fats or oils to carry them into the fatty tissues of the body.

Nutritional Constituents of Gac Fruit

Not so with gac fruit, because in addition to the beta carotene and lycopene content, it is also rich in long-chain fatty acids, particularly linoleic and alpha linoleic acids. Not only that, but its beta carotene content is around ten times that of carrots, and it contains 70 times the lycopene of tomatoes! Vitamin C is another very powerful antioxidant, and gac contains 60 times the Vitamin C of oranges. It is also rich in other free radical busters, such as xeoxanthins and alpha-tocopherol, a form of vitamin E.

Altogether, gac fruit contains a free radical killing arsenal that should be enough to scare even the most courageous free radical back to where it came from. Other constituents of gac are numerous minerals, particularly zinc and iron.

That is why the sweet gourd is such a prized fruit, and why Southeast Asian women have skins that western women of the same age would die for! Antioxidants help to prevent the disruption and destruction of skin cells that are the major reason for aging looks, and why skin creams are packed with vitamins A and E, both strong antioxidants.

Health Benefits of Gac

Most of the health benefits of gac are provided by its antioxidant properties. Thus, if you have a high cholesterol level, gac can help you to avoid atherosclerosis by preventing the oxidation of the LDL cholesterol, which is the precursor to it depositing on your artery walls. The body needs cholesterol, but levels should be kept to within certain limits or the resultant atherosclerosis can narrow your arteries leading to cardiac problems and strokes, particularly in the very narrow arteries of the brain.

Gac also supports the immune system and helps to maintain prostate health, largely through its alpha tocopherol, or vitamin E content. Vitamin E is easily destroyed by free radicals, which is where the beta carotene is of benefit. This is the body’s first line of defense against free radicals, and each molecule can neutralize up to 20 free radical molecules before it is destroyed. This helps to save other antioxidants such as vitamin E.

Lycopene is particularly beneficial to the prostate and current research indicates that it can help to prevent prostate cancer and cardiovascular disease, plus some other diseases such as macular degeneration that affects your sight. Perhaps this is one reason why the gac fruit membranes are used in Vietnam to promote healthy vision, and they also help to cure dry eyes. Lycopene remains in your body fat longer than normal beta carotene, and recent studies have found that men with high amounts of lycopene in their body fat are up to 50% less likely to suffer heart attacks as those with low amounts.

Gac fruit is jam-packed full of nutrients and antioxidants, and has no known side effects. It is used in Asia for weddings and other special occasions, and is grown on lattices in many gardens, although it has a short season. However, gac fruit is not known as the “Fruit from Heaven” for no reason, and if you were allowed the choice of only one fruit in your life, then this would be the one.

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Date: August 14, 2008 09:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants

Antioxidants are the body’s main defense against free radicals as they work against the substances that create oxidants and the reactive substances that result from oxidation and reduction. Antioxidants neutralize free radicals by supplying the missing electron so that the molecule may be stabilized. There are many different types of antioxidants ranging from dietary antioxidants to those that the body produces itself. The four major antioxidant nutrients are vitamin A (beta carotene), vitamin C, vitamin E, and selenium.

Vitamin A, the first vitamin to ever be isolated, is essential for the proper function of the eyes and maintenance of the skin. It is found in the retina of all mammals as well as the liver. Vitamin A works to increase our resistance to infections by keeping all the linings in the body healthy. It is necessary for the health and moisture of the skin and the specialized cells lining the eyes, nose, mouth, throat, lungs, esophagus, stomach intestines, and urinary tract. When these cells don’t have sufficient vitamin A, they thicken and harden, which is extremely detrimental to health and makes us more susceptible to infection. Vitamin A also protects the body from cardiovascular disease and cancer, and is necessary for new cell growth, something that is extremely important in slowing the aging process.

Beta carotene is the best known of the two carotenoids that form vitamin A, being composed of two vitamin A molecules that are split apart by liver enzymes when the body is low in vitamin A. If body levels are sufficient, the enzymes remain inactive and beta carotene does not divide, making it a safe source of vitamin A, without producing the toxic effects that come with high levels of vitamin A itself. If excess beta carotene is consumed it is stored in fat tissue or circulated in the blood. Beta carotene is one of the most powerful antioxidant nutrients as it can prevent free radical formation and inactivate existing free radicals. Once free radicals have been formed, it traps them and breaks the chain reaction that occurs.

Vitamin C holds a crucial role in many body processes that are necessary for life, among these being its role in collagen formation. Collagen is important in the every structure of the body, as it works like glue to bind cells together to form tissues. The integrity of collagen depends on vitamin C. Vitamin C also functions as one of the most powerful free radicals to prevent the damage that contributes to aging and age-related diseases.

It also works against pollution and toxins that damage cells and cause mutations, possibly even reducing some food carcinogens and protecting lung lining fluids against damage by air pollution. Vitamin C is important in the immune system and it also increases immunity to infectious diseases, lowers total cholesterol, enhances the effect of vitamin E, promotes wound healing, growth, tissue repair, and helps with the utilization of iron.

Vitamin E prevents aging by prolonging the useful life of cells found in the body. It also works to protect vitamin C and vitamin A from free radical activity so that they may remain potent. Vitamin E has the ability to stop a free radical chain reaction as it is happening and plays an extremely important role in preventing the per-oxidation of lipids (cholesterol). It protects the cell membrane, which in turn causes it to help protect the body from disease.

Selenium, one of the ten essential trace minerals, can be found in all tissues of the body. It is best known for its antioxidant role and its function in fighting cancer. It protects the liver from damage and works to stop lipid per-oxidation. Selenium is vital in maintaining the elasticity of body tissues and preventing the oxidation of fatty tissue, in turn combating the effects of aging. Selenium causes the skin to be healthier, muscle mass and tone are more easily maintained, and the heart is strengthened. Selenium works along with vitamin E, enhancing the effects of each other. It is important to get our vitamins and minerals on a daily basis to maintain a health happier life.

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Date: August 09, 2008 11:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Magnesium

Recent studies have found the importance of magnesium as a nutrient and its impact on general and heart health. Nutritional magnesium is deeply involved in the production of energy, the uptake of oxygen, the function of the central nervous system, the balance of electrolytes, the metabolism of glucose, and the activity of muscles, including the heart. When magnesium’s importance in the heart muscle is closely examine, the microscope is necessary, as it gets right down to the cellular and molecular levels.

Magnesium has an essential role in many of the functions of energy production and is an integral part of the energy and protein molecules, without which the heart would not have the proper energy to contract and relax. Magnesium is also essential in the construction of the cell membrane, as the heart is composed of cells and the magnesium plays a role in the strength of the heart muscle itself.

When magnesium levels begin to get too low the body will try to adapt, but the basic functions of energy production and cell structure are affected. Without enough magnesium, the cell is unable to keep the proper number of high-energy molecules that is needed to function properly. It doesn’t just end there though, as just about everything starts to go once magnesium falls below a certain level, and then cellular damage can result. Sodium balance and electrolyte balance also start to change, while the cell is unable to have a fully integrated membrane system due to magnesium deficiency, calcium and sodium start to rush into abnormal areas for the muscle cells which can cause cellular damage.

If a person is not getting adequate magnesium, they may go into a marginal state, which can be taken to a depleted state with a certain trauma or excessive physical, emotional, or mental stress. This depleted state can manifest as hypertension, high cholesterol, heart disease, and possibly even a heart attack. Magnesium requirements increase during times of stress which include exercise, mental and emotional issues, high noise, chemical toxins, and others. Requirements for magnesium also rise during healing from a bodily trauma such as an injury or operation. A low magnesium condition can be worsened by a high intake of calcium, as calcium can not be optimally utilized without the proper balance of magnesium, and a high calcium intake without magnesium will cause further drainage of any magnesium reserves. Although calcium is necessary at the cellular level for muscles to contract, nerves to fire, and hormones to be produced and released, too much calcium and too little magnesium is a disaster. Another problem related to heart health is cholesterol, a fatty substance found in many areas of the body. Since cholesterol has gotten such a bad name, many people do not know that it is actually produced in all cells naturally and is important for proper bodily functions.

Finally, one of the reactions that are involved in cholesterol production is called rate-limiting reaction, as it keeps control of the amount of cholesterol manufactured. The rate-limiting reaction requires magnesium, which can cause cholesterol to continue to be manufactured beyond the cells control if magnesium is unavailable, resulting in cholesterol buildup. As you can see, magnesium is vital to the body and if not obtained from your diet, should be supplemented through a vitamin supplement from a health food store. For more information on magnesium and its healthful effects on the body, feel free to contact your local health food store.

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Date: May 16, 2008 02:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coral Calcium

The health benefits of coral calcium were discovered in 1979, when a British journalist representing the Guinness Book of records traveled to Okinawa to talk to Shigechiyo Izumi, who at 115 years old was at the time the world’s oldest documented living human being. Not only was the journalist impressed and surprised at how healthy such an old man was, but he also found that good health to be shared by the majority of Okinawa’s aged residents.

After his report was filed on his return to England, a team of researchers were sent to the island to make further investigations in the phenomenon. They found that the key to their longevity was the water they were drinking. The water of Okinawa appeared unique, and coral calcium was discovered.

It was not only the calcium, of course, that made such as difference but the whole mineral balance of the water. Okinawa is formed of coral reefs built up over millennia, and rainwater filters down through the coral collecting minerals and other nutrients on its way. This water is both alkaline, with a pH of 8.6, and closely resembles the natural mineral composition, not only of the human skeleton but also of body fluids such as blood plasma and amniotic fluid. It seemed the ideal stuff to bottle, and there are now over 4 million users of coral calcium in Japan alone.

The commercial use of Sango coral, as it is called, is controlled by the Japanese government, and living coral is left untouched: only the dead coral sand lying on the ocean bed is used. The sand is collected and cleaned, and then pulverized and the calcium and all the rest of the minerals it contains are easily absorbed by the body.

It is this ease of absorption that renders coral calcium so useful. Most minerals find it difficult to pass from the intestine to the bloodstream, but this is not a problem for the minerals in Sango coral. Because they do not come from inorganic mined minerals, but from natural organic sources, they are present in a very bio-available form and are readily absorbed into the bloodstream. It not only contains the common minerals calcium, magnesium, potassium, sodium, and so on, but also many trace elements that are essential for life. Not only that, however, but they also contain antioxidants to help prevent the oxidative stress caused by free radicals, and also at a pH that allows the minerals to become naturally ionic very readily.

It is this ionic form of each mineral that permits it to be so readily available to your system. This was a major discovery at the time, since the form that inorganic minerals generally come in had been a problem prior to this to the extent that only 10% was absorbed by the body. In comparison, 95% of the coral calcium and other minerals are able to be easily absorbed since they are in an ionized form – an even higher absorbency than colloidal minerals allow.

Why are minerals so important and how can they possible lead to such an effect on the elderly of Okinawa? In fact minerals are very important components of human metabolism and biochemistry. Most believe vitamins to be significantly more important to human health than minerals, but this is not the case. Many vitamins are useless without the synergistic effect of minerals, and the reverse is also the same.

For example, calcium needs vitamin D to be present before it can be used by the body to strengthen bone structure. There are many other such interactions involving vitamins and minerals, and without chelation (the rendering of large organic molecules to a soluble form by combining them with metal ions) many of the essential biochemical processes of life would be impossible. Coral calcium contains all the minerals found in your body, and in very similar proportions, so that you are able to use it to maintain that all important synergism and not throw the mineral balance of your body out of balance. This is very easy to do if you take individual mineral supplements.

However, there is still more to come from this remarkable substance. It is also rich in antioxidants that spell death for free radicals. Free radicals can’t really die, because they are not living entities but molecules that have a free electron, and free electrons like to pair up with other electrons. Free radicals are therefore very aggressive when near any body cell from which they can rob an electron, and that, unfortunately, destroys the cell.

Not only that but they also oxidize molecules from which they take the electron, and if that is a low density lipoprotein, or LDL, that happens to be carrying some cholesterol to one of your arteries that needs a bit of repair work, then it will cause the LDL to deposit the cholesterol immediately and form plaques that constrict and narrow your arteries. That is called atherosclerosis and it can kill you or give you a stroke. Cholesterol is essential for good health, but once the free radicals get to work you are better without it.

However, Sango coral contains substances that prevent the free radicals from oxidizing other substances, and in so doing destroy them. That’s what antioxidants do. They prevent free radicals from oxidizing other molecules and creating all sorts of havoc with your health. Excessive amounts of free radicals have been associated with over 80 different conditions, and one of the benefits of coral calcium is that it is one of the most powerful antioxidants known.

It is not only the mineral content and antioxidant properties of coral calcium that are of benefit to the human body, but also its pH. The various fluids of your body are maintained at a specific pH, which is a measurement of the acidity or alkalinity of a fluid. This should be slightly alkaline without being caustic. If your body fluids are too acidic it becomes difficult for you to absorb minerals and vitamins, and it is essential for you maintain a balance of from around 6.4 to 7.0 Any lower than that and you will find it difficult to sleep and you will feel listless with no energy.

You can measure the pH of your body by testing your urine with pH strips available at any pharmacy. Coral calcium can be used to maintain a good pH level that allows your body to absorb the nutrients it needs, and keep you feeling not only well, but young and sprightly just like Shigechiyo Izumi did at 115 years old.

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Date: May 15, 2008 01:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Copper

Copper is an essential trace mineral necessary for life, and it is necessary for the proper function of certain enzymes that allow certain biochemical functions of the body to take place. Without copper neither plant nor animal life would be possible.

Dietary sources include nuts, grains, seeds, beans and other vegetable protein sources. Although it is also obtained from animal sources, these tend to be rich in zinc, and for reasons that will be discussed shortly, the presence of zinc can deplete copper absorption. Other common sources are copper cooking utensils and drinking water from copper pipes. After digestion, copper is absorbed into the body through the stomach and the small intestine. It is also possible for copper to be absorbed through the skin from copper bracelets.

Once absorbed, copper is bound to albumin and taken by the blood to the liver, where it is bound to a plasma protein known as ceruloplasmin. Among the enzymes with which copper is associated as a ‘helper’ are Cytochrome C oxidase, used in the conversion of glucose to energy, Dopamine hydroxylase, an essential component in the biochemical production of adrenaline, and superoxidase dismutase, that protects against the oxidative damage of cell tissue. Of particular benefit are its anti-inflammatory and antioxidant properties, and its role in energy production. Because of its antioxidant effect, copper could well play a very important role in protecting against atherosclerosis, and cardiovascular disease, the ravaging effects of free radicals on body cells and also certain forms of cancer.

Copper is also important in electron transport, and is responsible for the blue coloration of the blood of most molluscs and many arthropods. This is because rather than hemoglobin, these animals use the copper-based hemocyanin for oxygen transport in the blood. Rather than the iron-containing hemoglobin making the blood of these creatures red as it is with mammals, theirs is blue due to the hemocyanin. Copper salts are generally green and blue, as are the blue copper proteins plastocyanin and azurin.

So how is copper used by the body? It is, after all, fairly toxic, as little as 30 grams being fatal to humans, bringing on similar symptoms to those of arsenic poisoning. It is in fact the reason for its toxicity that also renders it so useful to the body. The toxicity is largely due to the ability of copper to accept and donate electrons as it changes between oxidation states. This results in the generation of very reactive radicals that can cause severe oxidative stress. The complete reason for its toxicity has yet to be determined, but the stress caused to body cells by free radical oxidation is a very serious condition.

It is this rapid change in its oxidation state that is valuable to the enzymes with which it is associated. The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase. In doing so the copper is converted to the monovalent state.

It also helps to aid in the production of the strong antioxidant Superoxide dismutase (SOD). What this enzyme does is to catalyze the formation of oxygen and hydrogen peroxide by the dismutation of superoxide, a negative ion consisting of two oxygen atoms and a free electron, and hence a very powerful free radical. Dismutation is the simultaneous oxidation and reduction of the species, rendering the free radical relatively harmless. This type of action on free radicals is a very powerful one, and essential in the body’s fight against such free radical species that are so dangerous to animal cells.

SOD exists in more than one form, and can also contain zinc, manganese and nickel in addition to copper. The internal fluid (cytosol) of practically all eukaryotic cells (cells containing a nucleus) contain a form of Superoxide dismutase dependent on copper and zinc, while most mitochondria contain an SOD with manganese.

Another of the important uses that your body can find for copper lies in the production of hemoglobin. This is because copper is needed for the storage and release of iron to produce hemoglobin, the protein in red blood cells. It is believed that ceruloplasmin is involved in the catalytic formation of ferric iron by the oxidation of ferrous iron, so allowing the iron to be attached to a protein that transfers it round the body to enable its use in the biosynthesis of various ferrous compounds, especially of hemoglobin.

Copper bracelets are commonly worn by arthritis sufferers, and there is a scientific explanation for that. As previously inferred, it is believed to be possible to absorb copper through the skin and copper is known to be involved in the formation of collagen and is a commonly used treatment for arthritis and osteoporosis. Part of its effect on arthritis is likely due to the antioxidant effect of the SOD that helps to reduce the inflammation at arthritis sites.

Although a deficiency in copper can lead to serious health problems, an excess is also harmful. Potential conditions include neurological problems, liver damage and bone abnormalities, although deficiency is far more common because of the competition between copper and zinc. Zinc is a copper antagonist, as is iron and manganese, and copper imbalances can be moderated by the use of these as supplements.

The symptoms of a copper deficiency include fatigue, hair loss, stunted growth, anorexia and a host of other conditions. Luckily, however, a deficiency is rare and most people receive a sufficient amount of copper in their diet. Supplements are available to ensure an adequate intake.

There is still much to be learned about the interaction between copper and enzymes, and there is also a great deal still to be learned of its role in human metabolism and biochemistry than is currently known. However, sufficient is known already for us to be certain that copper is a very important trace element and that we should be certain that our intake is sufficient, given that zinc iron and manganese compete to prevent copper being absorbed by the body.

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Date: April 28, 2008 02:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cherry Fruit Extract

Cherry fruit extract contains organic compounds known as flavanoids, which is a form of phytochemical frequently found in highly colored fruits and vegetables. If you eat a fruit such as pomegranate, blueberry, blackberry or cherry, or if you eat red peppers, aubergines and broccoli, you are eating foods that are rich in flavanoids.

Such foods provide you with remarkable health benefits that your ancestors knew about but did not understand. They ate these highly colored foods because they knew they helped prevent certain medical conditions, and to help others get well faster. They knew nothing about phytochemicals – chemicals contained in plants – or flavanoids, but knew about the results of eating them.

In fact, flavanoids are very powerful antioxidants and anti-inflammatories, and each of these require more detailed explanation since between them, oxidants and inflammation are responsible for most of the non-infectious common ailments of the human body. First, let’s have a look at antioxidants.

In chemical terms oxidation is the removal of an electron from an atom or molecule. There are species within your body known as free radicals whose sole purpose in their short life is to steal an electron from the nearest molecule to them. This is almost instantaneous, and most free radicals are very short lived. The concept of free radicals roaming your body and your bloodstream waiting to pounce on the first unwary molecule is a fairy tale. In fact the vast majority react as soon as they are formed.

When they do react, they remove an electron from a stable molecule, render it unstable and thus destroy it. If that molecule is part of a cell, and enough of them are robbed of their electrons, then the cell is destroyed. One result in visible terms is wrinkling of your skin, as your skin cells become destroyed, and hence you age quicker. In terms that you are not immediately aware of, oxidation can lead to many unwanted changes in your body.

For example, the low density lipids, that carry the cholesterol in your blood to areas of the body where it is needed, are oxidized by free radicals which causes the LDL to deposit along with their cholesterol on the walls of your arteries as a layer of plaque. Eventually that will build up to constrict the artery and cause a condition known as atherosclerosis – the arteries become blocked, and you can suffer from heart attacks and strokes.

These free radicals are formed by the normal metabolism of the body when energy is created in the cell mitochondria, by pollutants such as pesticides, cigarette smoke and traffic fumes, and by radiation such as excessive exposure to the UV radiation in sunlight.

Flavanoids, contained in cherry fruit extract, are antioxidants, which prevent this oxidation of body cells from taking place. They do so by being in the right place at the right time. If a flavanoid molecule is close to a free radical when it is generated, then the antioxidant will reduce the free radical and neutralize it.

If you eat a lot of cherries, or drink cherry fruit extract, you will be consuming a massive amount of flavanoids molecules that are ready and willing to destroy these free radicals. However, that is not all that flavanoids do. They are also, as has already been stated, anti-inflammatories.

The inflammatory response is the reaction of the body to a foreign presence such as bacteria. The tissues around the infected area receive an increased blood supply, and the cell walls produce gaps allowing the large immune system blood cells, or macrophages, to pass through. The temperature around the area increases due to the concentration of blood, and this itself is controlled by the body since bacteria die off after a certain body temperature has been reached, hence the reason for fever in the immune response.

The area swells up due to the concentration of fluid and protein, and becomes painful due to pressure on nerve endings. Anti-inflammatories, such as the flavanoids, work to relieve the symptoms of inflammation without interfering with the way the immune system deals with infection.

Many inflammatory conditions occur without any apparent reason, and while anti-inflammatories might not be used to suppress the immune system, it is used in such conditions as rheumatoid arthritis where the inflammation is a mis-firing of the immune system. Cherry fruit extract can be used to alleviate many similar conditions such as gout, and osteoarthritis where its use is well known and recorded.

It can also be used to help reduce the effects of atherosclerosis through its anti-oxidant properties, and cherries contain, not only a good supply of flavanoids, but also anthocyanins, another group of powerful antioxidants. They also contain vitamin C which is also a strong antioxidant.

Another property of flavanoids is their collagen strengthening properties, which they achieve by cross-linking the fibers to form a string fibrous network. That can be used to strengthen the walls of veins, and render them less liable to stretch or expand, thus providing them with the rigidity needed to prevent varicose veins caused by the puddling of blood below weak valves. They have the same effect on arteries, providing increased strength and a reduction in the blood pressure needed to pump blood round the body.

A good intake of cherry fruit in your diet will help to improve the condition of your cartilage and other connective tissue in addition to your veins and arteries, and is particularly appropriate for athletes who place great stresses on connective tissues such as the tendons that transfer muscular energy to the levers – the long bones.

In summary, then, cherry fruit extract and the flavanoids and anthocyanins it contains, posses properties to help relieve the symptoms of gout, and various forms of arthritis, to reduce the likelihood of cholesterol oxidation that leads to heart disease and strokes, to help strengthen the walls of veins and arteries and to improve the strength of connective tissue such as cartilage and tendons.

In other words, to improve the quality of life of the majority of the population that suffers from one or more of these conditions. After learning about the health benefits of cherries and all the mounting evidence in research, my question to you is why did the FDA make cherry farmers pull the health benefits of cherries from their websites with threats of legal action if not removed? Makes a person wonder who is on our side and who isn’t?

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Date: April 24, 2008 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Activated Charcoal - Highly absorbent material to combat poisoning

Activated charcoal has been treated by heat to open up millions of small spaces between the carbon atoms and turn it literally into an atomic sponge that adsorbs both organic and organic impurities.

This heat treatment is carried out in the absence of oxygen, so the charcoal cannot burn. Instead, what oxygen it did contain is driven off leaving behind all of these interstitial gaps that multiply the effective surface area by factors of ten. Since it is the surface area of the charcoal that determines its potency, then the greater this is the better.

Activated charcoal has a massive surface area, and just ten grams has the same surface area as nine American football pitches or 77 tennis courts. Ten grams is just marginally more than a third of an ounce. The term adsorb has a different meaning to absorb, and while a real sponge absorbs water by mopping it up through capillary action and suction, activation carbon adsorbs substances through a form of chemical attraction. You get rid of water from the sponge by squeezing it, but that doesn’t work with activated charcoal, since the substances are bound to it, not just physically constrained.

This huge surface area provides activated charcoal with innumerable bonding sites, and when chemicals that are attracted to carbon pass by they are attached to the surface. They cannot get free again, as water in a sponge can, but are bound to the surface of the carbon. Because the digestive system has no effect on charcoal then whatever is bound to it passes naturally through the body.

It is most effective at binding other carbon-based materials, and other substances with the right electronic arrangement, but others will just pass straight through. Because it is a chemical process, once all of the empty bonding sites have been taken up, the charcoal loses its effectiveness and has to be replaced. It is possible to regenerate it, but hardly worthwhile for you to do so because of the small quantities you use.

Because of the way it works, activated charcoal can help people to recover from some forms of food poisoning. It can adsorb gases in the intestine and help to relieve the pain of excessive gas in the gut. It has many additional uses that will be touched on later, but for now we will look at its effect on poisons because that is where activated charcoal is of greatest benefit to us.

It does not adsorb and neutralize all poisons, but is very effective with those that it can be sued for. Professor Touery proved a point when he drank a lethal dose of strychnine in front of colleagues at the French Academy of Medicine in 1831 and came through unscathed. He had mixed the strychnine with activated charcoal, and the fact that he lived after drinking a dose that would certainly have led to a very painful death within minutes testifies to the powerful effect of activated charcoal as an potential antidote for poisoning.

Ever medicine cabinet should have an emergency supply of activated carbon, especially those with young children in the household. However, this is not good news for the pharmaceutical companies who have reacted by refuting some of the claims made in its favor: they have claimed that it is not effective against arsenic. If that is so, then how did Michel Bertrand survive after swallowing 5 grams of arsenic trioxide – 150 times what is regarded as the lethal dose? He did this is 1813 after mixing it with activated charcoal, just as Professor Touery was to do 18 years later with ten times the lethal dose of strychnine.

It is true, however, that it does not have this degree of activity with all poisons, and it has no effect on cyanide, alcohols, antifreeze (glycols) and lithium. It also has no effect on corrosive poisons such as the strong alkalis used in oven clearers, or hydrocarbons such as kerosene. The way it works is adsorb the poison and prevent it being released into the body. For that to happen, the poison must have an affinity for carbon, and its adsorption site, and not all substances possess that property. Those that do however are permanently bound and therefore safe.

For charcoal to be effective in neutralizing a poison, it must be swallowed within an hour of taking the poison, or the poison will be too far advanced ion the digestive process for the charcoal to do any good. Keep in mind, though, that it is not selective, and activated charcoal can adsorb nutrients and other beneficial constituents of your body’s chemistry. It is important therefore that you take in only when necessary: you might need several doses if the poison was severe, but once it has done its job it is not meant to be used as a maintenance material to take ‘just in case’. Used like that, it can do harm.

If charcoal can adsorb poisons then it makes sense to believe that it can also adsorb some of the harmful agents that cause food poisoning. Not all food poisoning of course, but certainly those organisms that emit toxins that are attracted to carbon. And this is, in fact, the case. Food poisoning is caused by bacteria rather than viruses, and is not the presence of the bacteria that make you vomit and feel very ill.

As bacteria grow in your body they release toxins, or poisons, into your digestive system. These poisons are what make you ill. They can seriously affect the complete gastro-intestinal tract, causing vomiting, diarrhea, and inflammation and swelling of the small and large intestine. The latter can cause abdominal cramps and severe colic, and the severity of the symptoms depends very much upon the type of bacteria and the number of them in your body.

Many of these toxins are attracted to carbon since they are frequently organic based, and activated charcoal can be used to adsorb them. Once adsorbed they lose their potency, and since carbon is not digested by the body, they are passed harmlessly through the colon and eliminated in the faeces. It can also be used to eliminate many other foreign bodies from your gut, including viruses and fungi and might possibly reduce the concentration of uric acid, which can bring relief to gout sufferers.

Activated charcoal has many uses, and is normally available in capsule form. It can be dangerous to take too much, particularly if you suffer from intestinal problems that cause constipation, because the charcoal itself can have that effect. However, there is no better emergency treatment for accidental poisoning in the home, although, since it is not suitable for all poisons, you must still regard poisoning as an emergency and contact the emergency services.

Activated charcoal, or activated carbon as it is sometimes called, is also a good emergency treatment for vomiting and the other unpleasant effects of food poisoning. It deals with bacterial toxins in the same way as any other, though once again you must refer to your physician before or after using it – preferably the former.

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Date: April 16, 2008 01:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Coenzyme Q10 is an important cofactor that is found in nearly every cell of the body. Coenzyme Q10 is naturally produced by the body as well as attained through the foods we eat or in supplement form. With out it, every cell in our body could not produce energy to function and we would die. Coenzyme Q10 has the capability to regenerate antioxidants, protecting cells and DNA from oxidative stress which naturally occurs in the body every day.

Some may say that coenzyme Q10 exists in only one form, but in fact this substance exists in at least three forms in the body naturally. These three forms are CoQ ubiquinone, CoQH ubisemiquinone and COQH2 ubiquinol all of which are metabolically active forms of coenzyme Q10.

Ubiquinone has been commercially available for more than 30 years normally consumed orally, but recently stable forms of Ubiquinol have been made available for consumption which is of great interest by many researchers. The former ubiquinone when ingested had to be reduced by an enzymatically driven conversion from ubiquinone to Ubiquinol in the digestive tract. This conversion is done by the transfer of electrons effectively reducing the coenzyme Q10 to a more usable form Ubiquinol.

Once Ubiquinol is produced the body can more easily manufacture ATP which is directly used by cells for cellular energy. In young individuals, 90 percent of coenzyme Q10 found in the blood is in the Ubiquinol form. This being the case, the old form (ubiquinone) was less absorbable then the newer Ubiquinol that can go right to work in the body. Ubiquinol is considered the strongest lipid soluble antioxidant that is biosynthesized, providing an active defense against oxidative stress that damages, cells, proteins, lipids, and DNA.

Some scientists believe that cellular damage from free radicals cause our bodies to age. The older we get the less our bodies produce coenzyme Q10 which in its self is an antioxidant and restores other antioxidants in the body to fight the war against free radicals. Eating foods rich in antioxidants and or supplementing with antioxidants may slow the aging process.

With age, disease, and some prescription medications, the old form of coenzyme Q10 can not easily follow the process of absorption in the intestinal tract where it is reduced and shuttled through the lymphatic system into the circulatory system (blood). This is why Ubiquinol was so highly sot after. Ubiquinol is already reduced, the preferred form coenzyme Q10 the body wants to circulate and retain.

When one ages, energy levels always drop and one tends to slow down and feel tired sooner in the day, this may be because of a drop in coenzyme Q10 in the blood. Many recent studies suggest that the plasma Ubiquinol ratio is reduced in response to cardiovascular disease, neurodegenerative disease, cancer, fatigue and especially in type-2 diabetes. Supplementing with Ubiquinol can help restore plasma levels and boost ones energy levels and possibly slow diseases.

To sum it up, if you are over 45, suffering from a degenerative disease or cancer, feel tired and run down, or taking prescription medications, conventional coenzyme Q10 is not what you want to take to elevate plasma levels. Ubiquinol is needed because the body can not adequately produce the most abundant form of coenzyme Q10 in he blood (Ubiquinol). So for those who want to maintain health and wellness, look for Ubiquinol in their local health food store.

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Date: April 12, 2008 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins

Bilberry extract is taken from the Vaccinium myrtillus, or bilberry, a small blue berry that has been used traditionally for the treatment of conditions now known to be due to inflammation and the action of free radicals on the body.

Among these is atherosclerosis, or hardening of the arteries, caused by the free radical oxidation of the low density lipids that carry cholesterol around the bloodstream, and that cause deposition of fatty plaques on the arterial walls and eventually constricts them to a stage that can cause heart failure or a stroke, depending on whether the arteries are close to the heart or in the brain.

However, additional to treating this condition, bilberry has also traditionally been used for the treatment of varicose veins and also for certain eye conditions. In fact it was during the Second World war that the Royal Air Force in Britain received reports from pilots that their night vision improved after eating bilberries. Not only their vision, but the restoration of night vision after exposure to glare.

This was extremely important to war-time pilots who had to be able to rapidly adapt their vision to fly their plane after exposure to searchlights and explosive detonations. That is the reason for anything that appeared to promote this essential adaptation to be reported.

The pharmacology of these effects have been found to be due to the anthocyanosides in which bilberries are particularly rich. Anthocyanosides consist of an anthocyanaidin backbone, to which one of either arabinose, galactose or glucose can be bound. Since bilberry contains five of these anthocyanadins, then there are fifteen different anthocyanosides in the fruit concentrate.

The area of the retina that appears to control night vision, and the transition from day to night sight, is called the epithelium which is connected with purple vision. Anthocyanosides seem to have an affinity for this part of the retina, and in so doing plays an important part in this type of vision, specifically night vision although it is also beneficial in improving day vision.

Although bilberry also contains vitamins A and C, hydroquinone and tannins, it is the anthocyanosides that provide it with its unique antioxidant properties, and also its effect upon collagen fibers. It can cross-link collagen fibers to help overcome weaknesses in the connective tissues such as cartilage, tendons and the walls of blood vessels.

Its effect as an antioxidant is to prevent the cleavage of collagen by the cyzymes that are secreted by leukocytes generated by the immune system. By preventing histamine release, and release of prostaglandins and other proteins and cells mobilized during the immune inflammatory response to the detection of foreign invasion into human tissue, anthocyanosides can help to reduce inflammation and to protect against other extreme reactions of the immune system that can harm the organism it evolved to protect.

The most powerful property of anthocyanosides are their antioxidant properties: perhaps even its only property once all of the conditions it helps to protect against are fully understood. An antioxidant combines with free radicals and destroys them. Free radicals are particularly vile chemical entities that require an electron to make them stable, and they take this electron from the nearest source. This can result in oxidation and destruction of many bodily tissues leading to premature aging, atherosclerosis, eye damage and many other problems that result from the destruction of body cells and tissue.

The various constituents that make up bilberry act in concert to scavenge the free radicals and increase the supply of oxygen to the eye. The benefits of this are in helping to prevent cataracts and glaucoma, the latter due to the effect of the anthocyanoside cross-linking effect on the structure of the collagen in the eye. It can also help in cases of macular degeneration that affects the central area of the retina which might be due to the same property of there glucoside.

Moving away from the eyes and back to the vascular system, the collagen cross-linking properties of the flavonoids, which is what anthocyanosides basically are, can help to repair damaged vein tissue by strengthening the vein walls themselves, and also by providing support for the cell membranes, or outer layers of the cells.

This in turn builds up more strength in the vein tissue below the outside walls and contributes to an overall reduction in the weakness of the vein. This in turn enables it better to withstand the internal pressure put upon it by the failure of the valve that created the problem. In this way bilberries can be used to help repair the damage done by varicose veins and improve the function of the vein in returning blood to the heart from the extremities of the legs and also to help reduce the pain and swelling of varicose veins.

In addition to these beneficial effects on the vascular system and the eyes, bilberry can also help to decrease the permeability of the blood-brain barrier to pollutants, drugs and other undesirable chemicals by improving the resistance of the capillaries in the brain to the transfer of such substances through their walls. It does so by preventing the collagen of the capillaries in the brain being degraded either by enzymes or other agents, Also, by helping to strengthen that collagen structure so that it becomes more impermeable to the larger molecules that form the pollutants.

A lesser known constituent of bilberry is myrtillin, an anthocyanoside monoglucoside that is also available in all green plants, that possesses anti-glycemic properties. What this means is that it can reduce hyperglycemia and glycosurea, and so reduce blood sugar without reducing the blood sugar level to dangerously low levels. In other words it is an ideal insulin substitute.

Native Americans used green plants for teas for centuries and were free from diabetes until the came into contact with Europeans and adopted their dietary habits. Although the case has to be proved, it appears highly likely that it was the myrtillin that kept them free from a condition that affects so many other races.

Irrespective of that, however, it is for its powerful antioxidant effect that bilberry finds its best use, and also its effects on varicose veins. However, all of the above health benefits that bilberry provides, can likely be laid at the door of the combined antioxidant effect of its vitamin C content and the anthocyanosides – including the glucoside myrtillin.

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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Date: March 19, 2008 08:17 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Beta Carotene Is The Safe To The Liver Form Of Vitamin A

The fact that beta carotene is stated to be a safe form of vitamin A suggests that vitamin A is in some way unsafe. In fact an overdose of vitamin A can lead to any one of a number of conditions, including nausea, jaundice, vomiting, abdominal pain and headaches. This vitamin is fat soluble, and so any excess is not easily washed out of the body but can build up in the tissues.

Toxicity in the liver can occur at fairly low concentrations, and the toxicity of the vitamin is increased by excessive alcohol intake. However, toxicity only occurs with vitamin A already formed such as that obtained from liver.

There are several forms of vitamin A, including the retinoid form originating from animal sources and the carotenoid forms that have a vegetable origin. Carotenoids are converted to vitamin A in the liver, but the higher the concentration of beta carotene in the body, the smaller the percentage that is converted to vitamin A, so beta carotene is a safer source of vitamin A than retinoids. It is only the finished form of vitamin A that is toxic, and beta carotene is therefore self-regulating in its production.

This vitamin is stored in the body in the form of the alcohol (retinol) and of retinyl esters. Studies have indicated that as much as 95% if the stored vitamin is in the form of the ester. The liver is responsible for releasing vitamin A to the body as it is required. One of its better known effects is on vision, and the old wives tale that carrots help you to see in the dark has an element of truth in it.

In order for it to aid vision, retinol is oxidized to the aldehyde, retinal, that forms a complex with a molecule of opsin, a light sensitive protein found in the retina. Rhodopsin, as the complex is called, is an essential component of the biochemical chain of events that lead to the perception of light. It is extremely sensitive, and enables you see in very low levels of light. In other words it is essential for good night vision, so carrots do help you to see in the dark! When a photon of light hits a molecule of rhodopsin, it leads eventually to an impulse being sent up the optic nerve to the brain.

One of its properties is its reaction to white light. When rhodopsin is exposed to white light it loses its pigmentation, and hence its photoreceptor properties and can take 30 minutes to regenerate. That is why you lose your night sight if your retina is exposed to bright light. The more rhodopsin you can generate the quicker you develop night sight.

The other biochemical processes of the vitamin include the synthesis of some glycoproteins and maintenance of normal bone density. Without vitamin A, calcium is not properly absorbed by the body and glycoproteins are involved in this process. A deficiency of vitamin A can lead to the abnormal development of bone and other health problems, so there are limits between the levels of vitamin A in the body that must be maintained: above or below these limits will lead to health problems, some of which can be extremely serious.

Most of the biochemistry of vitamin A in the liver is initiated by the presence of alcohol, and otherwise it is though to passively store the vitamin until needed when it is released into the blood. There are several ways in which the presence of alcohol allows the liver to deplete its store of retinol, but generally there are a number of enzymes that, in the presence of ethanol, can render vitamin A into a water soluble form that is excreted by the urine.

The benefits of vitamin A other than its effect on night sight and the healthy development of bone tissue, includes a powerful antioxidant effect that neutralizes free radicals that can destroy body cells. These free radicals are generated by the body’s metabolism in generating energy from blood glucose, and are also created through exposure to pollutants such as cigarette smoke and traffic fumes. They are electron deficient, so when they are generated they grab an electron from tissue close by which destroys the cells involved. This can lead not only to the appearance of premature aging as the skin cells are damaged but also to serious health problems such as atherosclerosis and some forms of cancer. Vitamin A helps to protect against these by destroying the free radicals before they can do damage. It also helps build up resistance against infections by supporting the immune system.

Beta carotene is converted to vitamin A either by cleaving at the center of the molecule, or by breaking it down from one of the ends. This latter process is carried out in the small intestine, and the resultant vitamin stored in the liver in the ester form. Only a proportion of what you eat is converted to retinol ester in this way, and the more beta carotene you consume, the less is converted, so you can never suffer from an overdose of beta carotene-derived vitamin A. It might turn you yellow, but you won’t suffer from excess vitamin A since the excess beta carotene is stored in your body fat, including the subcutaneous fat reserves.

Alpha carotene can also be used in the synthesis of vitamin A, but not as actively as beta carotene. The best natural sources are fruits and vegetables, especially the red, yellow and orange varieties such as carrots and apricots, and also the leafy green vegetables, although supplements are also a convenient way of maintaining your beta carotene uptake. It is a much safer supplement than straight vitamin A for the reasons explained earlier. The supplement is not useful just for its antioxidant effect, but also for its ability to protect you from excessive exposure to the sun. While not as effective as a good sun blocker, beta carotene does provide some protection.

There is no doubt that beta carotene is a safer way to maintain an adequate vitamin A uptake due to the fact that you cannot take an overdose, since an overdose of beta carotene does not translate into the same dose of vitamin A, and the change is self-regulating. It is therefore safer to obtain your vitamin A needs from colored fruits and vegetables or beta carotene supplements than from eating liver, from which the retinol is in a form that can cause damage in the event of consuming an excess.

The old adage that you should never eat polar bear livers is a true one, and certainly has a provable scientific basis, so use beta carotene as your main vitamin A source for maximum health benefits in the safest possible way.

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Date: February 15, 2008 02:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Alpha Lipoic Acid is a Powerful Antioxidant

The discovery of alpha lipoic acid at the University Of Texas Chemistry Department in 1951 was not heralded with trumpets of joy at the revelation of such a powerful antioxidant, but was instead largely ignored. This is largely due to the biochemistry involved not being fully understood at that time, but by the 1980s it was a commonly used supplement, recommended for several medical conditions.

Chemically, the substance is a 5-membered cyclic disulphide with a carboxylic acid grouping. Biochemically, it’s extremely powerful antioxidant properties are largely due to the fact that it one of those rare active molecules that are soluble in both water and fats, and in fact is the only such antioxidant currently know. One of the properties that this ability enables it to possess is to cross the blood-brain barrier, and apply antioxidant propertied to the brain.

Antioxidants are essential to human life in that they destroy free radicals. These are compounds with free unpaired electrons that destroy human body cells in their hunt for electrons to pair with. electrons come in pairs in organic animal tissue, just as they do in organic compounds. However, under certain circumstances this pairing can become destroyed, leaving a molecule with one of its electrons without a partner.

The factors that lead to this situation are many and varied, and our own biochemistry can produce free radicals during the normal chemical processes of life. However, pollution can also lead to the oxidation processes that create free radicals, common such pollutants being cigarette smoke, vehicle exhaust fumes, pesticides and the like. Excessive exposure to the UV content of sunlight can also create free radicals as can eating barbecued and smoked foods, and exposure to carbon monoxide and peroxides. Even the biochemical conversion of glucose to energy in our bodies creates free radicals.

These free radicals can destroy body cells, including DNA, and can create conditions such as premature aging due to destruction of skin cells, destruction of brain cells, strokes, cancers, diabetes, atherosclerosis due to oxidation of LDL cholesterol that deposits in the main arteries of the body, stiffening of the joints and many other undesirable conditions.

Free radicals are destroyed rapidly by antioxidants: the reaction is very rapid and most are destroyed immediately they are formed before they can do harm. Fortunately, if your diet is well maintained, the body possesses many antioxidants such as vitamins A, C and E, and other substances such as Coenzyme Q10, flavanoids, xanthenes, polyphenols and carotenoids. Many of these are found in highly colored foods, and if your food is brightly colored, it should contain a good supply of antioxidants.

However, the problem with all of these is that they are either fat and oil soluble or water soluble, which means that they can either be freely carried round the body by the blood or have to be emulsified by the bile and transported via the lymphatic system that places restrictions on their effectiveness in certain organs of the body. The fact that alpha lipoic acid is soluble in both water and fats enables it to be carried to all parts of the body and to every organ, and can cross water/fat barriers that other antioxidants cannot do.

It can therefore be carried via the blood to the brain and carry out an essential antioxidant function within our brains. It took a long time for this property of ALA to be recognized and its consequent health benefits understood. It is, in fact, the ideal antioxidant. The substance provides many known benefits to the body due to its antioxidant properties and also helps the body to generate the maximum possible amount of energy from the blood glucose and thus improve the energy balance of your body.

However, it is with its antioxidant properties that we are most concerned here. One of the benefits of these properties is its effect in holding back the visible effects of aging on your body. Because it is both water and fat soluble, alpha lipoic acid can help destroy free radicals in every part of your skin; the areas served by the blood and the fatty and oily secretions are protected simultaneously by the same strong antioxidant. The end result is a reduction in the destruction of the cells through the dermis and epidermis and a reduction in the degree of wrinkling with age.

Its antioxidant effect in the brain renders ALA in great demand for reducing cognitive impairment with age. In fact studies have indicated that alpha lipoic acid can improve memory and brain function in the aging and the elderly. This effect appears to be increased by the synergistic combination of alpha lipoic acid and acetyl-L-carnitine that work together to prevent cognitive decline in the brain through the effect of free radicals.

There is evidence that during a stroke, ALA works synergistically with vitamin E to reduce the effect of free radical damage on the vulnerable brain cells, and so reduce the longer term effects of the stroke. Together with ALC, it also reduces oxidative stress on the mitochondria of cells and in so doing helps once again to reduce the effects of aging, and maintain the body’s capacity to generate energy from blood glucose.

Cardiovascular disease is the main killer of the western world, largely due to our diets, and this is especially true of the USA. Although Americans appear unable to change their unhealthy diet, alpha lipoic acid and acetyl-L-carnitine can be used to offset much of the damage done. ALA reduces the development of atherosclerosis through its antioxidant properties and the reduction of the adhesion of monocytes to the artery walls.

LDL trapped in the wall of the artery can be oxidized and enable monocytes to also enter under the surface of the arterial wall, where it changes into macrophages and ingests the oxidised LDL, causing the plaque that forms atherosclerosis. As the plaque thickens, the artery becomes increasingly restricted until the blood flow is significantly reduced or even stopped, causing cardiac failure or a stroke.

Alpha lipoic acid can prevent this free radical oxidation from occurring by destroying them before they act on the low density lipoprotein (LDL). Acetyl-L-carnitine works with the ALA to achieve this, as does another substance known as carnosine. Between them, these three musketeers work to keep your arteries clear and your brain functioning as it should, though it is the ALA that is most powerful due to its oil and water solubility properties.

Although alpha lipoic acid is available as a supplement, either alone or in combination with acetyl-l-carnitine, it is also available from natural food sources. It is particularly rich in offal such as heart and kidney, and also in broccoli, spinach and brewer’s yeast. It is also available in beef, and it is here that burgers can perhaps repay some of the damage that it causes. However, it is not a recommended source since burgers still cause more damage to your health than any of their constituent nutrients can allay.

Like any other supplement, you should seek medical advice before taking any substance if you have a health condition. Nevertheless, the benefits of alpha lipoic acid are such that it is difficult to see it doing anything but good. However, please consult your physician if are taking other drugs.

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Date: February 03, 2008 02:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acai: The Super Antioxidant From Brazil

Acai is an Amazonian palm tree, and possesses small purple fruits that the Amazonian natives of Brazil have used since time immemorial as food and as a remedy for certain health conditions that are now known to be associated with the activity on free radicals on body cells.

The active constituents of acai are powerful polyphenols and anthocyanin antioxidants that protect your body cells from oxidation by free radicals. In fact the plant has been referred to as ‘the super antioxidant from Brazil’ by many medical writers who have recognized its right to be termed as such. To understand that, you first have to understand what an antioxidant is and how it works. The chemical names of the active substances it contains will be meaningless without that background knowledge.

Oxidation occurs in your body even before you are born. What is does in general terms is to destroy your body cells, and the more it progresses the more your body is prone to cancers and cardiovascular diseases, and the more visible becomes the aging process. Chemically, oxidation is the loss of one or more electrons by an atom or molecule. Oxidation within your body is highly associated with what are known as free radicals. To explain these we have to consider the chemistry of electron pairs and free radicals, though this is not too technical so read on.

Normally electrons exist in pairs of opposite spin: in simple terms each pair makes up a single negative charge. Take hydrogen: its atomic structure contains one proton and one electron. However, the hydrogen atom cannot exist by itself since the most stable configuration is that electrons exist in pairs with a net zero spin, so the hydrogen molecule consists of two hydrogen atoms with their own protons sharing an electron pair. This is true of all covalently bonded molecules.

However, certain influences, such as pollution through tobacco smoke, pesticides, engine exhausts and the excess UV radiation of sunlight can cause a molecule to lose an electron. This creates what is known as a free radical: a molecule without an electrical charge but with an unpaired electron. Since the most stable configuration for it is to have a paired electron, the molecule will steal an electron from the most suitable candidate it finds.

In practise this will be a body cell, and the cell that loses the electron gets destroyed causing aging of the skin and many other undesirable effects, including cancers. This stealing of an electron is chemically referred to as oxidation. Antioxidants prevent this occurring to your body cells by being reactive themselves and preferentially mopping up these free electrons.

Polyphenols and anthocyanins are powerful antioxidants, and that is why the people of the Amazon rainforests have used acai not only as a food, but also for their health. It is only relatively recently that, as with many of the ancient health remedies, the scientific basis behind its use has been proved. The early Brazilian natives may not have understood biochemistry or what free radicals were, but they sure knew what was good for them.

As with many other foodstuffs containing powerful antioxidants, it is likely that it was the highly colored berries that first attracted them. That does not suggest that all brightly colored foods are good for you, but the brightly colored pigments and dyestuffs contained within them also tend to act as antioxidants due the same electron configuration that provides them with their color. Many of these chemicals are also use as food dyes, and have been used so since before their chemistry and antioxidant effects were known. The color comes from the same electron activity that makes them destroy free radicals. That is why most highly colored foods contain significant quantities of phytochemicals.

The deep purple color of the acai fruit led chemists to determine its content of polyphenols, such as anthocyanins, that are common in other highly colored foods such blueberries, peppers and aubergines. High concentrations of anthocyanins such as cyandin-3-glucoside and the rutinoside analogue were found, together with flavonoids such as orientin, deoxyhexose and scoparin. A total of twelve flavonoids were discovered that explains the highly antioxidant properties of the fruits. Laboratory and other tests have indicated that over 80% of the antioxidant effect of acai is due to polyphenols other than the anthocyanins. It is likely that these are the twelve flavonoids identified to date and any others that have still to be detected.

However, it is not only for its antioxidant properties that acai is such a healthy fruit, since it contains many other nutritional components. It contains fatty acids, including linoleic acid, an omega-6 fatty acid and also beta-sitosterol that are believed to reduce the level of LDL cholesterol in the blood. The fruit also contains a high level of amino acids, essential for the synthesis of proteins and DNA.

So what exactly does this mean for you in real terms? Antioxidants can do different things for different people, and the acai berry is said to have more than thirty times the antioxidant power of red wine. When you consider that many doctors believe one glass of red wine to provide sufficient antioxidant for the average person, you are getting a very high dose with acai berries, so what does it do for you?

Due its effect in destroying the free radicals caused by pollution, acai and similar powerful sources of antioxidants are becoming increasingly important to our diets. What was a sufficient antioxidant intake even twenty years ago is not longer sufficient. Acai can help to combat early aging by reducing the rate at which your body cells are destroyed by free radicals. It also reduces the risk of cardiovascular disease, and the associated high risk of strokes or heart attacks.

Acai juice itself has an unusually high fiber content, and helps maintain the health of your digestive system. An associated benefit of this is that you are less liable to contract colon cancer than if you did not consume it. Due to a reduction in the rate of destruction of body cells, including brain cells, elderly people benefit through maintenance of their brain function, and a lower likelihood of degenerating cognitive ability. It helps you to maintain concentration and memory, and can also reduce the risk of you getting cataracts.

Antioxidants are also known to help maintain the immune system, and act as anti-inflammatories, and it is believed that acai juice can help to reduce the symptoms of arthritis. If you use acai berries as part of a daily diet, you should receive the benefits that it provides, although a more measured dosage in the form of a supplement will enable you to control your intake of acai, and if one thing is certain it is that you will be far healthy with a regular dose of the superantioxidant from Brazil than without.

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Date: January 31, 2008 09:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Astaxanthin, a Member of the Carotenoid Family, is a Powerful Antioxidant

Astaxanthin is a member of the carotenoid family responsible for the red color of many types of algae. Being a carotenoid, it is a powerful antioxidant and free radical scavenger as well as support proper eye function.

However, such a bland statement belies the true worth of astaxanthin in its fight against free radicals. It is of particular benefit in its ability to absorb the high energy of singlet oxygen, releasing it as heat, and returning the singlet oxygen to its ground neutralized state. Singlet oxygen is a particularly harmful and reactive oxygen species of free radical that is formed in the body as part of our normal metabolism, and that contains a high level of free energy that can be used to oxidize and destroy the cells of your body.

In achieving this, astaxanthin is regarded as one of the most potent plant derived antioxidants known, being up to ten times more active than beta carotene, Lutein or its cousin canthaxanthin. So why are antioxidants so valuable to our biochemistry and what would happen if they did not exist?

Free radicals are thieves that use your body as their operating ground. They operate by stealing an electron from a molecule that comprises part of you, and in some cases when this occurs the cell from which the electron is removed is destroyed. Generally electrons go around in pairs, but occasionally an electron pair can lose one of the electrons during a chemical reaction. Many such reactions occur naturally inside the body, especially during the production of energy from blood sugars in the mitochondria, and such a molecule containing a single unpaired electron is called a free radical. Free radicals are also generated by the reactive components of many pollutants such as traffic fumes and cigarette smoke, tars and pesticides, and also by the effect of UV radiation in sunlight.

The only purpose of a free radical is to steal an electron from the first source it can find. Such reactions occur very rapidly after the free radical has been generated, and if this electron belongs to another body cell, then the cell is destroyed leading to effects such as premature aging or even cancers. Free radical oxidation of the LDL lipids that carry cholesterol around the blood causes the deposition of fatty plaques inside arterial walls that eventually become constricted or even blocked, leading to heart disease or strokes.

That is why antioxidants that destroy these free radicals are so prized, and the more of them that there are in your body then the less affect the free radicals will have on you. You will retain your youthful looks longer, and will be less liable to suffer from heart disease, cancers, circulation problems and conditions such as diabetes. Many abnormal conditions can be laid at the door of free radicals.

The stronger the free radical, the more harm it can do to you and a strong antioxidant such as astaxanthin is a very powerful weapon in your armory against them. Astaxanthin is a member of the oxygenated xanthophylls, and its high level of antioxidant power likely comes from the ketonic and hydroxyl functional groups of the ionone ring structure. It is more polar than most carotenoids, and this is a likely reason for its ability to span the cell membrane layers, with the active groups close to the hydrophilic-hydrophobic interface. They are thus more readily available at the sites where most free radicals tend to be found and provide immediate protection to the cell membrane and also to the intracellular mitochondrial membrane.

Many antioxidants destroy free radicals by donating an electron, and become oxidized themselves. Astaxanthin, however, does not do this, but instead adds the free radicals to its long double bonded chain hence avoiding oxidation and rendering it much more powerful than normal antioxidants. It is unusual among antioxidants in that it is also able to cross the blood-brain barrier, and so reduces oxidative stress that can cause neurological disorders in general, and also problems with eyesight. It can also attach itself to lipoproteins to enable it to be carried throughout the bloodstream, being available anywhere that free radicals are generated. The carotenoid is also active against active oxygen species that are responsible for inflammation.

Another property is its ability to neutralize the oxygenated free radicals formed by the photo-oxidation properties of UVA and UVB radiation. Included in these are the previously mentioned highly reactive singlet oxygen and also triplet oxygen that astaxanthin is able to neutralize without becoming oxidized. In fact reactive oxygen species in general can cause oxidative stress, and they have been thought responsible for many forms of disease and health conditions, and the powerful effect of astaxanthin in targeting many of these has led it to be regarded as highly beneficial to the immune system and to health in general.

Another benefit is the ability of the substance to help prevent the oxidation of high density lipoproteins (HDL) that are responsible for carrying cholesterol in the blood back to the liver for destruction. Free radical oxidation of HDL impairs its ability to transport cholesterol, and so decreasing the level of such free radical oxidation will by definition increase the quantity of good HDL available, and hence reduce the concentration of cholesterol in the blood. Studies have proved this to be the case, and astaxanthin supplements are very beneficial to those suffering from high blood cholesterol levels, and helps protect them from heart disease and strokes.

The substance is naturally available from a wide range of marine sources, such as lobsters (where it was first discovered), shrimp, salmon, trout and in a wide variety of red and green algae. The substance is also used as a red pigment. Carotenoids are essential, meaning that they are not produced in the human body and can only be obtained in our diets.

For that reason, the most convenient way to take it, apart from continually eating shrimp and lobster, is as a supplement. Astaxanthin is available either as a powerful antioxidant in its own right, or in combination with other substances with which it acts to provide a very strong deterrent to any free radicals that think they can freely roam your body.

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Date: January 21, 2008 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Seniors Need More Than a Multiple with Only 100 Percent of the RDA

The aging process is a gradual one. That might seem obvious, and it is, but it is the fact that it is gradual that causes people not to notice the small but significant changes in their body that are taking place. Aging is more than just the oxidation of skin cells that cause them to wrinkle, but involves specific functional cell changes, such as their ability to multiply.

As this slows down the immune system is affected, and we find it more difficult to recover from injury and disease. Oxidation becomes more prevalent and free radicals become more common as the natural antioxidants of our bodies become overwhelmed. We are less able to recover from the effects of environmental stress, such as UV radiation from the sun, pollution and the effects of heat. We find it increasingly difficult to deal with a lack of nutrition or toxins in our food from pesticides. In short, we become less capable of dealing with attack by invaders, but do not notice this gradual lack of immune response.

Age also affects our joints from the vertebrae in the neck to the joints of our toes. The net result is a compression of the bones that causes a reduction in height. We also develop more body fat and less muscle tissue, which is a significant consideration in planning the nutritional needs of the elderly. However, of more critical importance when discussion the nutritional needs of our aging population is the possibility of malabsorption.

Malabsorption is an inability of the digestive system to absorb nutrients from food, and occurs in people of any age although it tends to be more prevalent in seniors. It is predominantly due to a dysfunction of the liver, the pancreas or the small intestine that are the three major physical components of the human digestive system.

The liver produces bile that is needed to process the fats in your food, and if the bile is not delivered to the small intestine, then malabsorption is possible. The same is true of the enzymes that are produced by the pancreas These enzymes are important components in the biochemistry that allow us to absorb nutrition from our food, and since most of this absorption occurs in the small intestine, this too is essential for proper absorption. When any of these three are reduced in efficiency, as they are with advancing years, then malabsorption will occur.

When this occurs in seniors, however, it is essential that a multiple supplement with more than 100% of the RDA (Rcommended Daily Allowance) is used. This type of nutritional deficiency can be very serious at an age when so many normal biochemical processes are slowing down, and it is important that steps are taken to avoid the serious problems that can arise.

The immediate symptoms of malabsorption are diarrhea and weight loss, although the more serious longer term effects are anemia due to a deficiency in folic acid and iron and a reduction in the blood’s ability to form clots due to a deficiency in vitamin K absorption. There are others, but not all problems associated with aging are actually due to malabsorption, or even with aging.

Many of the problems associated with aging are now believed to be connected with the patient’s lifestyle and diet. Heart disease such as atherosclerosis is now known to begin earlier in life, as are many other conditions once believed to be associated with age. A loss of cognitive ability can be age related, but also due to cigarette smoking and excessive alcohol consumption. However, irrespective of all this, it is essential that the aged are provided with vitamin and mineral supplements offering more than 100% RDA.

Calcium is of particular importance for older women who are particularly prone to osteoporosis due to malabsorption of calcium from their food. At least 1000mg daily should be taken, and extra magnesium and vitamins A and E will also be necessary since they are needed for the proper absorption of calcium. The extra does not infer that all of the supplement will be absorbed, but that enough should be to help reduce the possibility of bone density problems.

The elderly are particularly prone to vitamin B deficiencies, particularly of vitamin B12, due to absorption problems and a good vitamin B complex supplement is needed. Chromium too can be seriously depleted in the aged, and this mineral is necessary to enhance the activity of insulin. It is also believed to play a part in the metabolism of carbohydrates, proteins and fats. There are no known consequences of an excess of chromium so a good supplement can be provided. It is believed that vitamin B and chromium together are required for cardiovascular and neurological health that are so important as we age.

One important supplement for the elderly is Coenzyme Q10. Many older people are prescribed drugs such as statins for the treatment of high cholesterol levels. Statins work by depressing the biochemical synthesis of cholesterol by blocking the action of mevalonate, and this is known to interfere with the metabolism of Coenzyme Q10, otherwise known as ubiquinone.

CoQ10 is essential in allowing the production of energy within the cell mitochondria by allowing electron transfer back and forth between NAD and NADH to allow the production of adenosine triphosphate (ATP). A supplement of this important enzyme is therefore essential in maintaining the energy levels of the aged who are being prescribed statins.

Almost 20% of the elderly on prescription drugs are also taking herbal remedies and supplements, and there could be an interaction between them. Anybody taking prescription drugs should consult their physicians before taking natural remedies or any form of supplement, and this is particularly true of the elderly.

However, where the elderly are safely taking a vitamin and mineral supplement, it is extremely important that this contains more than just the RDA. Absorption problems are very common in the elderly, and this excess can make sure that they receive more than they would otherwise, if not the whole recommended dosage of the particular substance involved. Better safe than sorry, especially where an excess is not known to cause harm.

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Date: January 18, 2008 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Give Your Health A Boost With Silica Hydride A Powerful Antioxidant

Hydride ions are strong proton acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.

A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.

Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.

This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.

The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.

This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.

An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.

Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.

In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.

Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.

Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.

Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.

If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.

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Date: November 22, 2007 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Support Healthy Joint Function With Discount Vitamins

The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime.

Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones.

Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain.

Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue.

A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders.

A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints.

The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover.

Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids.

Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks.

Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage.

Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement.

It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that.

That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results.

Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density.

There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium.

You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.

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Date: November 17, 2007 11:46 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Green Coffee For Protection Against Oxidative Stress

It is recorded that coffee drinking originated in Ethiopia in North East Africa, from where Arab traders introduced the plant to the Middle East. From there it moved to Turkey in the 15th century, where it was highly prized as a daily beverage due its invigorating properties. It is also believed that the infamous Captain John Smith introduced the plant to Virginia.

The Brazilian coffee trade was due largely to the introduction of the bean to that country by the French in 1727, and the Boston Tea Party of 1773 rendered it the only non-alcoholic drink worth consuming by the patriots of 18th century America. Now over 50% of Americans drink coffee daily, although this seems a somewhat conservative estimate, and the tea houses of England have largely been replaced by coffee shops and the ubiquitous Starbucks.

So much for the history of a beverage that has been prized for its stimulant properties, but recent research has established that not only is coffee a stimulating drink, but that it is a strong antioxidant due to its polyphenol content. However, not all forms of coffee have this property, only the green coffee bean before it has been roasted. Polyphenols are very powerful antioxidants that scavenge the free radicals that destroy body cells, and not only accelerate aging but also threaten the health of your cardiovascular system and the health of other major organs.

Free radicals are compounds with a spare electron. Normally the electrons in all stable molecules come in pairs, and any free electron without a partner is like a lovelorn bachelor. It will seek a mate, and take it from wherever it can find one. Usually it secures its partner by stealing an electron from one of our body cells. This can totally destroy the cell, as it might anybody who has its partner stolen, and cell destruction is not a good thing. It is the destruction of body cells that promotes the appearance that aging brings: the wrinkles and the loss of energy that is generated by healthy cellular activity.

Antioxidants destroy these free radicals, and come in a number of different guises. Vitamins A, C and E are all powerful antioxidants, as are many of the compounds that are essential to our biochemistry such as beta carotene and polyphenols. These polyphenols are found in practically all plants to a greater or lesser degree, and another rich source is grapes, and those found in green coffee beans are what are known as hydroxycinnamic acids the most abundant of which is caffeic acid. Another is chlorogenic acid, and together they form a very potent team in preventing the oxidation by free radicals of LDL (low density lipoprotein).

Low density lipoproteins are those that carry cholesterol from the liver to areas of the body that need first aid due to damage, such the arterial walls. However, this can be attacked by free radicals and oxidized which results in the deposition of excess cholesterol that can build up till it eventually constricts, and sometimes completely blocks, the major cardiac arteries. This is a serious condition known as atherosclerosis that can eventually lead to cardiac disease and arrest or to strokes if the artery is in the brain.

Not only do chlorogenic and caffeic acid help to prevent this from occurring, but they also help to prevent the cellular degeneration caused by the free radicals. They must be extracted from the green coffee bean because roasting or heating in any way, including brewing, destroys them. In fact, brewed coffee contains some potentially harmful substances called diterpenes that some believe can increase your chances of coronary disease by up to fifth if you drink coffee regularly over your lifetime.

It is also believed that green coffee extract can reduce the risk of diabetes due to its effect on your blood glucose levels. Evidence is coming to light that some polyphenols, including chlorogenic acid, might have inhibiting properties on the activity of glucose-6-phosphate, otherwise known as Robison Ester, which is involved in the metabolism of blood glucose and which is affected by diabetes which reduces its concentration. Chlorogenic acid is though to be able to redress this imbalance and not only reduce blood glucose levels, but increase the glycogen stored in the liver as an emergency energy source for the body.

Green coffee bean extract also possesses other beneficial properties, not the least of which is its effect in increasing the metabolism of fats in relation to carbohydrates. This assists in weight loss and also increases stamina. The decrease in the risk of diabetes of up to 50% in men, and slightly less in women, could be due to a combination of the regulation of glucose-6-phosphate and the regulation of blood glucose levels and glucose and weight management in general. The vast majority of diabetes patients are overweight.

In animal studies, the presence of chlorogenic acid appears to reduce the hyperglycemic peak that arises through the action of glucagon, a hormone used to counter hypoglycemia. The fact that chlorogenic acid reduced this sugar peak indicates its potential use in reducing abnormally high blood glucose levels. Another effect of this was an increase in the animal’s glycogen level and in the level of glucose-6-phosphate in the liver.

This indicates a reduction in glycogenolysis, by which glycogen is ultimately converted to glucose-6-phosphate and glucose, thus increasing the blood glucose levels and also of gluconeogenesis which is the production of glucose from carbohydrates and some glucogenic amino acids. In other words, green coffee bean extract can help to regulate blood glucose levels by preventing the liver from producing glucose from glycogen and carbohydrates.

However, the biochemistry apart, it must be stressed that these benefits are not obtained by drinking coffee, and it has to be repeated that the active agents in providing them are destroyed by the roasting and brewing processes. It is only the green coffee beans that can be used for protection of oxidative stress of human body cells and the gradual degradation into premature aging and many other related conditions.

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Date: November 02, 2007 04:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Build Healthier Skin With Antioxidant Rich Skin Moisturizing Lotions

Antioxidant rich skin moisturizing lotions can help you to build healthier skin, since they can help to allow the appearance of the fine lines that eventually develop into the wrinkles that you dread.

Most people think about caring for their skin more in the summer when the sun is hot than in the colder winter months, but cold can also dry out your skin since you tend to sweat less. However, the summer brings with it the harmful ultraviolet rays of the sun to a greater or lesser degree depending on your climate. Tough leathery skin is generally associated with skin neglect by white skinned people in the hotter areas of the world such as Australia and the southern parts of Florida and California.

You should look after your skin since it is important to you. It not only keeps everything inside that should be kept inside, but also generates vitamin D and contains the temperature control system that your body relies upon. Elephants flap their ears, dogs pant and humans sweat! Without your skin you would be in a bad way, so you should look after it. If you don’t keep it supple it gets dry and hard, wrinkled, itchy and can crack, into which the bugs and viruses needed to make you ill can enter.

All of this occurs when your skin loses its moisture. In order to keep it in tip top condition, and keep yourself looking young and attractive, you should keep it moist through the use of artificial moisturizers if necessary. So why does your skin dry out and how do moisturizers work to help overcome the effects of drying?

In fact the major problems that occur with your skin due to exposure to sun in the summer have nothing to do with drying out. Your skin actually does, as suggested above, become more affected by dryness in the winter when the relative humidity is low. It is in winter that you have to use lip moisturizer because of dry and cracked lips, not summer. However, summer has its dangers, even more than winter.

It is the UV radiation from the sun that damages your skin and can ultimately lead to skin cancer. The UVA and UVB radiation are at different wavelengths and have different effects. The combination, however, causes wrinkles, skin disorders when aging, premature aging, and dry leathery skin. Part of this is believed to be due to the breakdown of the collagen in the skin that maintains its elasticity, free radical damage and inhibition of the immune system.

When UV radiation breaks down collagen it causes the accumulation of abnormal tissue. When this builds up, enzymes are produced that are intended to repair the collagen, but sometimes it does not work properly and produces a disorganized and random accumulation of collagen fibers that eventually result in wrinkles.

Free radicals are chemicals that have a free electron available, rather than having all electrons in pairs as in stable compounds. It is therefore unstable and will steal an electron from healthy tissue and so damage the cell that it takes it from. Eventually, the cells die and genetic material within the cells can be altered. This can cause wrinkling of the skin and underlying tissues or even cancer by changing the DNA and RNA contained within the cell.

The final defense of the body against cell damage is paradoxically apoptosis, which is suicide by the damaged cells to prevent them becoming cancerous. This is what you see when your skin peels after sunburn – it is deliberate action on behalf of the cells of your skin sacrificing themselves to save the body as a whole. UV exposure can prevent this from occurring which is why it can lead to some forms of skin cancer.

However, it is the action of oxidants on the skin that cause most damage. The so-called drying out of skin is largely due to oxidant damage more so than to loss of moisture. The sweat glands in your skin can produce lots of moisture, but nothing can be done about free radicals other than provide the help of antioxidants to kill them off. Antioxidants destroy free radicals with glee, and hunt them down wherever they are. The common antioxidants in your body are vitamins A, C and especially the powerful vitamin E. That is why so many skin creams contain vitamin E, and sometimes also vitamin A.

However, there are many more antioxidants than these. Astaxanthin is one. ‘Asta what?’ I can hear you say, and I am not surprised. It is not very common in health stores, but has been approved by the FDA and in Europe as a food colorant. It is a terpene carotenoid, though does not break down to vitamin A in the human metabolism as other carotenes do. It is claimed to be fifty times more powerful as an antioxidant than vitamin E and acts as an internal sunscreen in the skin by blocking the harmful effects of UV radiation at cellular level.

It is available naturally in krill, salmon, trout, crustaceans and some bird feathers, and is extracted from microalgae. Not all sources are palatable and it is best taken as a supplement, or to protect the skin, in a cream. Another super-antioxidant is pycnogenol. However, be aware of purchasing it under this trade name in the USA, since the term has been hijacked by others who are selling a different product under that name. The true chemical pycnogenol as named by Frenchman Dr. Masquelier is a very strong antioxidant: any others are mere imitations that are not the same product.

Chemically, pycnogenol is a proanthocyanidin, a flavanol extractable from grape seed or pine bark. Any product that comes from a different source cannot be pycnogenol. That said, the product is able to strengthen the skin and prevent wrinkles through its effect in scavenging free radicals. It stops the free radicals from destroying the cells of the skin and causing premature aging. Whether the chemical is extracted from pine bark or grape seed appears to make no difference. The chemicals are virtually identical, or should be if they are from the right form of pine bark.

The polyphenols in green tea also eradicate free radicals. They too are very strong antioxidants, just one of the remarkable properties of this plant. However, none of these will be of much help unless specifically applied to the skin. If taken internally, they will do a great job of mopping up free radicals in the blood, but very little will actually reach the skin.

In order to build healthier skin, you will have to use antioxidant rich skin moisturizing lotions that apply moisture to your skin, but more importantly also apply these powerful antioxidants. If you really want to maintain good looking wrinkle-free supple skin in sunny climates, then look for one or more of the above substances as an ingredient in your moisturizing lotion.

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Date: October 24, 2007 11:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

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Date: October 22, 2007 10:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Consume Bright Colored Foods for Better Health

A plate of colored food is not only very pleasing to our eyes, but also very healthy. What looks good to eat is also very healthy for us and if you are finding it difficult to persuade your children to eat those boring old tired looking vegetables, then try brightening up their plates with some nice bright colors.

Kids love brightly colored pop and candy so it should not be a difficult thing to persuade them to eat some brightly colored vegetables like peppers, tomatoes, quashes and even thinly sliced carrots with a nice dip. The more intense the color the better for you they appear to be. Colored foods are normally packed full of anti-oxidants that help to prevent diseases of the cardiovascular system and to mop up free radicals present in our bodies. These antioxidants are all chemicals, and many of the naturally occurring antioxidants are highly colored. They are very good at destroying free radicals.

Free radicals are a form of chemical that destroy body cells, and not only accelerate the effects of aging, but also harm our heart. A free radical is a molecule with an unpaired electron. electrons like to go around in pairs. Every atom has pairs of electrons, and one atom has an odd number then it pairs up with another atom with an odd number, so the two form a compound with an even number of electrons.

However, now and again, the body’s metabolism throws up a molecule with an unpaired electron. That electron’s first thought is to find a partner, and it does so by stealing one from a cell in your body. The result is the disruption and destruction of the cell. Free radicals can also be formed by environmental pollution, cigarette smoke, pesticides and so on.

Anti-oxidants destroy free radicals, and generally keep us healthier for longer. They do so by mopping up the extra electron, and there are many different types of antioxidant that form part of our normal diet. Among them are vitamins A, C and E, but there are others that are complex highly colored organic compounds. Among these are the anthocyanins, known to paint and ink manufacturers as strong red pigments.

Anthocyanins are the pigments or dyes that color red grapes, egg plant, plums and blueberries and they are very powerful antioxidants. However, it is not only for antioxidants that we should eat colorful foods. Some dark green foods, such as spinach, green peppers, peas, celery and dark leafy vegetables, contain what are known as lutein. Lutein works in combination with zeaxanthin to protect our eyes from cataracts and a condition known as macular degeneration, which can lead to blindness. Zeaxanthin is available from red peppers, oranges, egg yolk and corn.

Many people take folic acid supplements help maintain a healthy heart, and especially women to help prevent birth defects. However, the natural form of folic acid, folate is available from green foods such as lettuce, green beans, broccoli, peas, green grapes, and many other green foods. Broccoli and cabbage also contain indoles also known as indol-3-carbinol are believed to protect your from some cancers. So green is good!

Yellow is also good, and foods such as grapefruit, pineapple and melon help to boost the immune system and keep infections at bay, and also to provide energy and help maintain healthy eyes. Many antioxidants are yellow, although yellow might not a color that you would associate as being attractive to children, unless very bright. However, the yellow foods tend to be fruits rather than vegetables, and it is much easier to persuade a child to eat a pineapple than a squash.

Lycopene is another very powerful antioxidant that prevents the oxidation of low density lipoprotein (LDL) cholesterol that can damage the cardiovascular system through atherosclerosis. Lycopene is a red pigment very common in tomatoes, and is fat soluble. It is a member of the carotenoid family of antioxidants that are common in brightly colored foods such as carrots, red peppers and many yellow fruits and vegetables as described above. Lutein is also a carotenoid.

A diet rich in carotenoids is very good for keeping the effects of aging at bay and protecting you from heart problems. Lycopene is contained in the liver, colon, skin and prostate gland, and can occur at higher concentrations than most other carotenoids. People that suffer from HIV infections, high cholesterol diseases and inflammatory conditions such as osteoarthritis, are generally found to have low levels of lycopene in their blood.

Many of the so-called ‘superfoods’ are also brightly colored, and useful not just for their antioxidant properties. Take cranberries for example. These bright red berries contain proanthocyanadins that prevent some bacteria such as e-coli from adhering to the walls of the urinary tract and cause urinary tract infections such as cystitis, and also from adhering to the gums. Cranberries can therefore be used in the treatment of some gum diseases. However, they also possess strong antioxidant properties that help to protect the body against some cancers and also heart disease.

Blueberries are high in vitamin C, potassium and antioxidants with strong anti-inflammatory properties. Pomegranates have exceptionally high antioxidant content and are excellent for a healthy cardiovascular system while strong green broccoli contains not only vitamin C and antioxidants but also folate (the natural form of folic acid) and the phytochemical sulforafane that is believed to protect against certain cancers.

The color of your food, therefore, not only makes it look pretty on your plate and attractive to children, but also indicates the presence of strong antioxidants and other chemicals that help to protect you from specific medical conditions. It is no coincidence that the vast majority of the so-called superfoods is vegetable in origin rather than animal, and also tastes good. You should eat as many of them as you can, and certainly at least five portions every day.

Some can also be used as a remedy for specific conditions in addition to being used for their preventative properties, such as cranberries are used in the treatment of diseases of the urinary tract, and specific diets can help to reduce the amount of LDL cholesterol in the body. Eating with your eyes is not always a bad thing. Some may find it hard to consume enough colorful fruits and vegetables to be beneficial so what is a person to do? Your local health food store has available powdered vegetable and fruit concentrates that supply all the needed nutrients in one simple drink.

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Date: October 21, 2007 07:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Staying Healthy Means Keeping Your Blood In The Proper PH

The blood should be electrolytically neutral, or very slightly alkaline. The proper pH for blood should be 7 or just above it, and many claim that it should be 7.35. In fact the truth is that your blood pH should be between 7.2 and 7.6. Outside these limits and you could have serious health problems, with your brain particularly being affected.

For those who have forgotten their school chemistry, pH is a measurement of the level of acidity or alkalinity of an aqueous solution. Anything over 7 is said to be alkaline, and below 7 is acidic. Where the pH has to be maintained at a certain level, a material called a buffer is used that counteracts the effects of other acids and alkalis to maintain the desired pH range. Buffers are very common in nature, as would be expected of life forms that depend upon water and aqueous solutions for their survival. Blood is an aqueous solution containing plasma, blood cells, nutrients and various other ingredients in both solution and dispersed solid form.

The human body possesses a very effective pH maintenance system that depends on various buffers, the kidneys and the lungs. Lets have a closer look at buffers and how they work. pH is, in fact, a measurement of the concentration of hydrogen ions (H+) in a solution. The way a buffer works is to absorb or release H+ ions to keep the hydrogen ion concentration at a specific level. If there are too many H+ ions present in the blood, and it becomes too acidic, then the buffer will mop up the excess. If there are too few, and the blood becomes too alkaline, then the buffer will release more hydrogen ions into the blood. In this way the pH is maintained at the limits mentioned above.

Buffers in the human body include some forms of protein, phosphates and also hemoglobin. However, if the pH variations are more than just occasional, the buffers have a limited capability, and a more permanent solution is needed. If the blood is continually becoming too acidic, the bicarbonate ion is used to clear them up. Just as bicarbonate of soda is used to clear up excess acidity in your stomach that causes indigestion, so it can be used to clear up excess acidity in the blood. But how do we get the bicarbonate into the blood?

When the lungs inhale oxygen, they then exhale carbon dioxide. The bicarbonate ion, also called the hydrogen carbonate ion, is formed in the blood by dissolved carbon dioxide. The faster we breathe the more carbon dioxide we exhale and the less is left in the blood to form bicarbonate. The slower we breathe, the more carbon dioxide is available in the blood for bicarbonate. Thus, when our blood acidity increases we breathe slower, and when it decreases we breathe faster since less carbon dioxide is needed in the blood to form bicarbonate to neutralize the acid.

The kidneys also help to regulate the pH of the blood, although the biochemistry involved is fairly complex, and will not be covered here. It is enough to state that the body has a number of routes by which it can control the pH of the blood.

Current thinking is that alkaline and acidic foods should be balanced in your diet in order to place less of a strain on the body’s pH control systems. Since the blood pH must be slightly alkaline, then it might make sense to eat a slightly alkaline diet. However, it is not the actual food that matters, but what happens when the food is digested. Hence, orange juice is classed as an alkaline food even though it is high in citric acid and itself has a low pH. The same is true of lemons. They taste very sour, yet the result after digestion is alkaline. It is the end result that counts. After all, the stomach acid is very strong and very highly acidic, and eating slightly alkaline foods is not going to alter that. The digestive juices have to be highly acidic to break down the organic matter.

It had been calculated that a mix of around d 75% alkaline and 25% acidic food is a good combination of the two types to provide approximately the desired blood pH. Among the common acidic foods are meat, fish, poultry, plums, grains, eggs, wine, cheese and offal. The alkaline foods are most fruits and vegetables, orange and lemon juice, melons, potatoes and chocolate. Hence, it is possible to eat beef and chicken, and have the odd glass of wine so long as we eat plenty of fresh fruit and vegetables. There is nothing at all unusual with that diet, and it underlines the importance of eating a healthy balanced diet. While more greens and whole foods are definitely healthier for you, you should not eat exclusively an alkaline diet.

If your blood pH is on the high side of the limit, then you can eat a bit more meat or fish, and if on the low side eat a more vegetarian style diet. It is important, however, that you eat healthily, irrespective of whether you are eating alkaline or acidic foods. Through history, the human race has adopted a more acidic diet than the ancient hunter gatherers. Grains are a relatively recent invention, introduced after the invention of stone tools to mill them, and dairy products are also relatively recent in terms of the whole of human history. Even the consumption of meat only began after mankind learned first how to trap and then developed tools to enable them to kill their prey.

Human biochemistry, then, has developed from a predominantly vegetarian diet. However, protein is still very important, and while protein intake is necessary, should comprise no more than 20% - 25% of your total food intake. The rest should comprise of mainly fruits and vegetables, with whole rather than refined or processes foods predominating. Sugar was not eaten in quantity until the industrial revolution.

Measuring the pH of your blood is easy to do. It is simply a matter of using pH paper strips and checking the color change with your blood. They are available at most pharmacies and health food stores. If your pH level varies from 7.4 or 7.5, then you should change your diet accordingly. Higher than this, then eat more acidic foods, and if lower you should eat more alkaline food. It is simple equation, and the changes you will have to make to your diet will be minimal. Some of these changes can be made by the use of supplements that are carefully balanced to maintain your blood in the proper pH.

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Date: June 02, 2007 02:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Exceptional Ingredients For Exceptional Performance

Anaerobic exercises, such as bodybuilding and strength training, as well as endurance based aerobic activities, such as marathon running and bicycling, are notorious for depleting the body’s reserves of glycogen, protein, electrolyte minerals, water, and other vital constituents. And as simple logic will tell us, the harder one trains, the more they will lose in the process. Failure to properly replenish these nutrients immediately after training can result in fatigue, delayed recovery, accelerated lactic acid levels, mental sluggishness, and intense soreness. According to research, immediate replacement of electrolyte minerals and carbohydrates, along with easily assimilated protein is an effective way to maximize amino acid utilization, when preventing the onset of fatigue. NOW electro Pro Energy Drink contains all the elements to ensure proper post-workout recovery. By combining a perfectly balanced mix of electrolytes, protein and simple and complex carbohydrates, electro Pro serves as an ideal supplement for recovering after intense training and exercise.*

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Carbohydrates

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*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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