Search Term: " Dopa "
Happier and healthier: Curcumin-rich turmeric can help easedepression and anxiety, researchers find
April 25, 2019 05:11 PM
Curcumin, the active ingredient in turmeric, can have benefits for mental health on top of its many benefits for cardiac and joint health and inflammation. Curcumin is believed to help reduce neuroinflammation — and the cytokines that help cause it — and moderate cortisol levels within the brain, while achieving more balanced levels of dopamine and serotonin. These actions may explain why a 2015 study indicates that turmeric supplementation can substantially improve the effectiveness of antidepressants in many people.
"Curcumin regulates levels of dopamine and serotonin in the brain, and it also decreases the markers of neuroinflammation, which is significant when you consider that inflammation contributes to mood disorders."
Read more: https://www.naturalnews.com/2019-03-11-curcumin-rich-turmeric-can-help-ease-depression-and-anxiety.html
Food GOLD: Turmeric is just as effective as 14 pharma drugs butsuffers from NONE of the side effects
April 23, 2019 01:53 PM
According to over 12,000 peer-reviewed studies, the herb curcumin has over 800 preventive and therapeutic uses. It is estimated that the health-enhancing properties of this powerful herb can replace 14 pharmaceutical drugs with no negative side effects. Research published in the journal Biochemistry and Biophysical Research Community shows that curcumin is up to 100,000 times more effective than the diabetes drug Metformin in activating AMPK, which is used to increase glucose uptake. In addition, a 2008 study revealed that curcumin is just as effective as Lipitor in decreasing oxidative stress and inflammation. Research also shows that curcumin compares favorably to Prozac in treating depression without any of the side effects, such as suicidal ideation, tremors, and headaches.
"Researchers believe it works on depression by inhibiting monoamine oxidase, the enzyme that has been linked to depression when it’s present in high amounts in the brain. It also raises levels of calmness-inducing serotonin and dopamine."
Read more: https://www.naturalnews.com/2019-03-07-turmeric-is-just-as-effective-as-14-pharma-drugs.html
Here's what research shows about the mental health benefits ofginger
March 29, 2019 01:14 PM
Taking in a consistent amount of ginger throughout the week is showing to have several positive benefits in terms of both physical and mental health. Not only can ginger help patients who deal with chronic pain such as arthritic discomfort by treating inflammation, but it can also help improve cognitive function as well. Our brains are continuously faced with pollutants found in the air and food we consume, which can directly decrease our brain's functionality. The dopamine levels replaced by ginger can help aid in protecting our brains from these potential threats.
"Ginger is often used as an anti-inflammatory, making it a popular natural remedy for arthritis. The plant’s anti-inflammatory property can also help people with brain disorders like ADHD, Alzheimer’s, anxiety, brain fog, and depression, which are often associated with chronic inflammation of the brain."
Read more: https://www.naturalnews.com/2019-01-27-mental-health-benefits-of-ginger.html
From OCD to depression to anxiety, learn how inositol can preventmany mental health disorders
November 13, 2018 08:51 AM
Living at maximum wellness constitutes more than having a disease-free body, where all the parts are doing what they should. Mental health is also a key component to overall health. From PMS symptoms all the way to psychotic episodes, more than 40 million U.S. citizens suffer from a mental problem yearly. Although treating these potentially life-clouding conditions with pharmaceutical grade interventions is the norm, these interventions are not without the possibility of potentially hazardous side effects. A B vitamin, inositol is present in the human brain in large amounts. Scientists are considering whether significant supplementation of the vitamin might be a way to treat an array of mental conditions naturally and without side effects. The vitamin has already been shown to have positive effect in some mental conditions, which makes sense, as significant neural transmissions depend on the use of the vitamin. Moreover, it's also been shown that individuals with lesser amounts of the mood-regulating chemicals, serotonin and dopamine, have lower levels of inositol. Although more research needs to happen in some instances, there is promising research to suggest that elevating inositol levels could prove efficacious for an array of mental conditions, including panic attacks, bipolar mood disorder, obsessive compulsive disorder and depression.
"In fact, other major neurotransmitters depend on inositol to relay messages, making it a key component in a lot of chemical systems in a person’s brain, including the ability to handle stress, learning and cognition, mood, productivity, sleep, and addiction."
Read more: https://www.naturalnews.com/2018-11-06-inositol-can-prevent-many-mental-health-disorders.html
5 Adaptogens That Will Improve Your Brain Function
August 29, 2018 10:53 AM
Adaptogens help protect your brain from stress and keep it working at peak efficiency. Ashwagandha, for example, can bolster focus, memory and cognition, as well as promoting the growth of new dendrites. Rhodiola can make neurons more sensitive to dopamine and serotonin, which increases mental clarity and focus, and has great potential for fighting depression and inflammation. Turmeric is an even stronger anti-inflammatory, and may help depression as well. Siberian Ginseng can help speed up processes in the brain, and improve learning and retention of new information. Finally, maca root can stabilize moods, fight brain fog and help inhibit breakdown of neurotransmitters.
"Adaptogens are substances that promote balance and negate the ill effects of stress in the body."
Read more: https://www.care2.com/greenliving/5-adaptogens-that-will-improve-your-brain-function.html
10 Reasons You should Be Taking curamed daily!
September 05, 2017 12:21 PM
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Eating your way to strong memory and mental health
May 21, 2017 10:44 AM
Serotonin works with various mind forms including state of mind, hunger, rest and memory. Dopamine works with discernment and delight. At that point we additionally have aggravation. Aggravation in our body can make harm our veins and cells in our mind prompting sicknesses, Alzheimer's illness. An eating regimen high in nourishments, for example, organic products, vegetables and solid greasy oils from fish, avocados and olive oil can diminish irritation. Along these lines, to battle against memory misfortune and to empower emotional wellness.
Read more: Eating your way to strong memory and mental health
How to stop sugar cravings this Easter
April 14, 2017 06:44 AM
Easter is a time when it is easy to be tempted by sugar. A craving for sugar is the body needed something that releases dopamine in the body. To avoid sugar cravings, there are a few tips you can take: 1. Eat small meals and snacks spread throughout the day; 2. Drink 6-8 glasses of water each day; 3. Avoid processed foods; 4. Distract yourself from the cravings by doing something fund; 5. Avoid white carbohydrates and instead focus on eating wholegrains; and 6. Try a natural food supplement to curb your appetite and get rid of cravings.
Read more: How to stop sugar cravings this Easter
Health Check: what makes it so hard to quit drugs?
December 17, 2016 10:59 AM
The brain becomes primed to repeat drug taking over and over without actually thinking about it. When the Dopamine system is damaged in that part of the brain, it makes it much harder to think through consequences and make considered decisions, so drug use becomes more automated. The wiring of the Dopamine reward system makes it compelling to use drugs, and the damage to the system makes self-regulation more difficult. The brain and body adapt over time to taking drugs and react when the alcohol or other drugs leave the system.
"Every drug affects different neurotransmitter pathways in different ways. Some affect more than one neurotransmitter. But most drugs impact the Dopamine system in some way."
How Glutathione Reduces Effects Of Parkinson's Disease
Parkinson's Disease is an incurable chronic and movement disorder that results from the death of neuron cells of the substantia nigra area of the brain. The symptoms associated with this disease worsen as one ages.When the neurons die, they release a chemical called Dopamine that is a neurotransmitter that relays messages to movement and coordination centers of the brain. As one ages, the Dopamine level produced decreases making it hard for transmission of messages to this part of the brain responsible for movement and coordination. This makes the patient unable to control movement of body parts.
Symptoms of Parkinson's Disease:
How To Reduce Effects Of Parkinson's Disease:
PD currently has no cure. However, doctors do surgeries and other medical procedures on affected parts of the brain to reduce effects of this disease. Researchers worldwide agree that there could be a breakthrough in the treatment of this chronic disease with the administration of glutathione (GSH) to patients. The supplement works in the following ways:
Our bodies naturally produce glutathione which is an antioxidant. Its production however reduces progressively as one ages. Its main role is to fight free radicals which may build up to cause oxidative stress. Patients should thus take the glutathione supplement daily to help them fight this oxidative stress which causes PD.
Glutathione also supports mitochondria. This ensures consistent energy production in mitochondria. This energy is useful in the fight of PD. Glutathione makes the brain effectively use Dopamine and detoxifies the body. This ensures that heavy metals which may attack the brain are regularly removed from the body. Numerous studies are however still underway to determine how this supplement can be used effectively. Glutathione should not be taken orally as it is broken down in the gut before it can be used in the brain cells.
Six reasons why walking is the best medicine for mental health
November 13, 2016 10:04 AM
Did you know walking can help you work better, help with addiction, make you happy and keep you young? Walking can make you more creative and give your confidence a boost in addition to creating new brain cells that can help with decision-making and learning. By releasing endorphins, walking can also make you feel happier and it can also help control addiction by increasing Dopamine. Walking can even help you age by sharpening memory and by preventing cognitive decline.
"A lot of people take up walking in hopes of getting fit or losing a little bit of weight, but many people find that it becomes a surprisingly enjoyable habit once they get started."
Curcumin Helps Alleviate Depression
Curcumin is a phenolic acid that can be sourced from the cooking spice turmeric. It acts as a powerful antioxidant in humans and protects the body's cells from dangerous free radicals (harmful by-products that are released into the cells during oxygen related reactions). Provisional studies suggest that it may also have many more health benefits. There is also some evidence that curcumin or turmeric may help alleviate the symptoms of certain skin diseases, viral infections, diabetes, colitis, stomach ulcers, and high cholesterol. Once again, the ancient herbal remedy is being celebrated as a modern wonder drug. But perhaps the most promising results have been seen in the use of curcumin to treat depression.
Curcumin vs. Prozac
If there's one thing Big Pharma fears more than anything else it's competition from the outside. Because herbal medicines have far fewer and less serious side effects than prescription pills, they would be the logical choice - if only they worked as well. Well, there is now irrefutable, ironclad scientific evidence that an herbal remedy is every bit as effective at treating depression as one of the most popular prescription antidepressants.
When researchers with the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India conducted a controlled clinical study comparing the effects of curcumin and Prozac, they didn't expect to make national, even global news. Although the popular herbal remedy is widely used in India, curcumin had never been subjected to rigorous scientific testing for the treatment of major depressive disorder (MDD). The most serious and chronic form of the disease, major or clinical depression affects about 3 percent of population at any given time. The idea that a chemical compound from a popular native spice could compete with Prozac seemed far- fetched to those conducting the study. But after 60 patients diagnosed with MDD were randomly administered curcumin, fluoxetine (Prozac), and a combination of the two, the results spoke for themselves.
With the help of the Hamilton Depression Rating Scale, 17-item version (HAM-D17), researchers determined that curcumin was just as effective as Prozac at treating serious depression. Because the study utilized the latest research tools and followed strict testing guidelines, it became the first published report that indicated the efficacy of turmeric or curcumin in the treatment of depression. What the report did not take into account, however, were the serious side effects those who take Prozac endure; the most serious of which include anxiety, seizures, racing heartbeat, trouble sleeping, and suicidal ideation.
How Curcumin Treats Depression
Shortly after the results of the aforementioned study made news, researchers started looking for answers. It was not enough for Western scientists to know that curcumin is effective in the treatment depression, they also had to know how. As you might imagine, the how has proved more challenging than the if. This is not at all surprising, since curcumin has diverse biological properties that are difficult to study separately. So, while the mechanism of action is poorly understood, the effects of curcumin intake are well documented, particularly with regard to neurotransmitters.
As their name implies, neurotransmitters send messages to the billions of neurons in the human brain. Some of these neurotransmitters are responsible for regulating brain functions such as mood, memory, appetite, and sleep. Known as "feel-good" neurotransmitters because they help maintain mood balance, Dopamine and serotonin play a role in depression. How do we know? For starters, studies have confirmed that people who suffer from clinical depression have consistently low levels of both neurotransmitters.
Once again, we aren't sure how curcumin extract works its magic, but testing has shown that those who take it have higher serotonin and Dopamine levels. That fact alone might account for the improved mood those that take the dietary supplement have consistently reported. Although researchers will undoubtedly get to the bottom of this ancient mystery, it enough for most patients to know that curcumin is a safe and effective treatment option.
Your Mood and mental health
Bipolar disorder is a terrible mental disease that affects millions of people worldwide. It is characterized by periods of severe depression, followed by periods of extreme euphoria. It can be rapid cycling, which means the person with the disease goes through many moods a day.
Once you figure out what the underlying cause such as brain chemistry, then you can take a natural approach to help boost serotonin or Dopamine.
Always remember to be careful if on MAO inhibitors or SSRI inhibitors before taking natural remedies like 5-htp or Dopabean to mess with serotonin and Dopamine levels in the brain.
Do you need to regulate hormones ? Experience Chaste Berries Powerful Effects
Would you believe that a simple berry could be the solution to hormone normalization and regulation? The Chaste berry has been shown to treat suffering from symptoms of menopause, menstrual irregularities, pre-menstral syndrome, and infertility. However, Chaste berries benefits do not end with women as the berry has also seen use as a natural way to balance hormones in men and may actually prevent prostate cancer.
Chaste berry, also known as vitex, has the ability to regulate and stimulate anterior pituitary functions and has been shown to restore normal estrogen to progesterone levels in women. This is accomplished by attaching to Dopamine receptors and decreasing output of prolactin. It is this process that allows Chaste berry to treat the multitude of different hormonal issues that it does and ultimately regulate and normalize hormone levels.
In conclusion, there are many different uses for Chaste berry when it comes to hormonal health. For women the berry has shown successful use as a treatment for PMS pains, fertility challenges, and abnormal menses. In men, Chaste berry has been used to prevent prostate cancer and balance hormones. Chaste berry has also been indicated to effectively treat acne in both male and females. Who would’ve thought you could get all that from one little berry?
Ashwagandha - Herbal Way to Reduce Stress
Mankind has tried every possible way to overcome the issue of stress. Among these, the natural and healthy ones include family get-togethers, yoga, meditations, or rituals. Others might show the same unwanted result on your body which includes, consumption of drugs, think cocktails, or midnight ice cream bings. Ashwagandha has a special name and place in ayurvedic arrangement of medicine as it is a successful herb for reducing stress. It is an herb utilized since ancient times that assistance to cool your mind and keep you free from stress and anxiety. Ashwagandha is a natural way to lessen stress. In today's fast moving life you may get a disease-free life by taking ashwagandha everyday. It will give you mental peace and will also enhance your working capacity. Ashwagandha serves to decrease stress as well as make your body disease-free. Ashwagandha has a property to decrease negative contemplations from your mind and deadheads in inspirational attitude. It gives you a new way of dealing with stress naturally. It supports your vitality and makes you solid from inside to face any more regrettable situation.
It feeds the weak cells in your body and help to give a superior performance. Ashwagandha brings peace in your life by balancing powers that act on mind, body and soul. Regular intake of this herbal stress reliever will give you great results within couple of days and you will start feeling better and see changes in the effectiveness of your work. Ashwagandha has a special property that relieves the mind and gives you a sound rest. Adequate rest is an important factor to diminish stress. Ashwagandha serves to induce natural rest. Many chemical medicines are available in the market that create a great deal of reactions and regular intake of such medicines make you habitual. You get to be subject to the medication and it delivers adverse impacts on different organs of the body. A herbal supplement, for example, ashwagandha is a natural answer for ease stress. It is totally safe and does not create any adverse impacts.
A man under stress turns out to be aloof and may attempt to confer suicide. Ashwagandha serves to take away such contemplations from mind by nourishing the brain cells. It also gives sustenance to other body cells and supports up your vitality level to deal with any situation naturally. Ashwagandha is also useful in treating gloom and anxiety. It cultivates positive considerations in mind and makes you feel happy in each situation. It revitalizes your body cells and tissues to give you more vitality. It increases Dopamine levels that assists in dealing with stress. Ashwagandha also serves to enhance memory skills. Ashwagandha is a complete tonic for your brain and sensory system and does not cause any adverse reactions.
Educative And Informative Details About NADH Supplement And Its Benefits
May 12, 2014 03:34 AM
What is a NADH
Nicotinamide Adenine Dinucleotide (NADH) is an activated form of B vitamin niacinin, which is available naturally in the body, from poultry, meat, fish and in minimal quantities from vegetables and fruits. This substance is also commonly referred to as the most important coenzyme mainly because of the import role of transforming food-based energy into energy, which can be utilized by the body cells. Due to the roles played by NADH, it has been developed into supplements, which have various benefits. NADH role in the body is important since the body cannot utilize the energy inform of whole proteins, carbohydrates and fats which are the main sources of energy.
How NADH works
Instead, when the foods that provide the body with energy are ingested, they are usually broken down into smaller parts after being absorbed and distributed into various cells. One of the things that are derived after these foods being broken down is acetyl, which is a two-carbon molecule. Enzymes are the primary components that break the foods into acetyl. However, enzymes require coenzymes to break these foods properly and extract the energy from acetyl. This makes NADH is an important coenzyme, which extracts energy from reactions between oxygen and acetyl. This coenzyme also helps in transforming tyrosine, which is an amino acid into Dopamine, which is a brain chemical.
Benefits of NADH
One of the primary benefits of NADH supplement is that the brain chemical it helps to produce known as Dopamine helps in improving various brain functions. Some of these functions which this chemical affects include; concentration, mood, muscle movement, sexual drive and energy. It also helps in athletic performance, slowing aging process, Parkinson's disease, depression and Alzheimer's disease.
This supplement is also helpful on people with chronic fatigue syndrome. This is achieved through helping patients reduce anxiety and reduce heart rate. Consequently, the patient is able to relax and allow the body to function normally. Therefore, NADH supplement is helpful and has many benefits if it is used properly.
Is Cocoa Butter Good For The Skin? Why?
March 06, 2014 03:27 PM
Doubtlessly, there are few preferred healthy skin items over cocoa butter and some few that likewise makes you feel great deductively notwithstanding feeling extraordinary because of the way your skin looks so great, but Cocoa butter is good solid skin reinforcement, and for additional data on characteristic healthy skin items with a great experimental foundation. Therefore it is good for the skin.
Reasons to why cocoa butter is good for your skin:
Powdered cocoa butter contains a lot of diverse antioxidants which behave synergistically presenting a massive bothersome resistant to the cost-free radicals which eliminate your skin layer cells along with lead to quick getting older. Therefore, therefore, is it doesn't suitable natural skin care solution.
Let's have a look at which record again. Precisely why your 'ideal' natural skin care solution? In order to solution which question, we need to have a look at precisely what antioxidants tend to be, along with precisely what hot cocoa butter can perform them, along with after that the reason why it is advisable than additional natural skin care merchandise on the market.
Totally free radicals tend to be small substances kinds in the body's fat burning capacity while vitality is generated coming from blood sugar in the mitochondria of each and every cell phone within your body. Fortunately they are shaped simply by experience of toxins including pesticides, along with particularly the several poisonous pieces of cigarette light up. Cigars along with water lines tend to be believe it or not harmful than tobacco, along with filtration system guidelines make not any difference towards the production connected with cost-free radicals.
What exactly that they do is always to eliminate cells, when they're pores and skin cells you continue to grow older. Your skin layer wrinkles along with dries up, and you begin to take on the style connected with an individual many years over the age of you're. These people try this by way of a procedure often known as oxidation, along with antioxidants can certainly keep the idea. These people reduce the effects of your cost-free radicals, and forestall your skin layer cells coming from getting ruined.
Contents of cocoa
Powdered cocoa butter contains several different antioxidants that can eliminate away from numerous diverse cost-free radicals along with superoxides, as well as hydrogen peroxide. Vitamin e is really a powerful antioxidant -- your strongest of all the so-called antioxidant vitamin supplements in fact, and will quickly eliminate away from hydrogen peroxide along with any oxidizing agent. Others tend to be vitamin supplements A new along with G, however they can not strategy the potency of vitamin E.
Furthermore, it contains phytochemicals (posh title pertaining to place chemicals) including flavanoids which might be also powerful antioxidants. Polyphenols are very effective in neutralizing cost-free radicals, and the hot chocolate mass polyphenols tend to be in particular successful. In fact, hot chocolate butter boasts a greater antioxidant awareness and then possibly blueberries as well as other so-called superfoods.
In order that hot cocoa butter to work, it will email numerous of the pores and skin cells as is possible, that involves do away with the idea properly directly into your skin layer. The epidermis is incredibly absorbent all of which will eliminate cost-free radicals in the reduced absolute depths of the pores and skin as soon as they're created, along with ahead of they are able to do injury.
It is clinically demonstrated which hot chocolate butter will certainly keep pores and skin degradation a result of the harmful consequences from the UV light in the rays of the sun -- UV rays builds cost-free radicals which are very effective in doing damage to pores and skin. Merely go through the influence connected with sunburn! However, there is additional in order to hot chocolate butter than which.
It contains a substantial percentage connected with vitamins as well as lime scale, potassium, magnesium, zinc, manganese, copper along with metal, all of which come in a highly bioavailable style which make them far better which business vitamins. Not just that, though. Furthermore, it contains tryptophan, involved in the development connected with serotonin, your 'feel good' neurotransmitter, and also Dopamine along with phenylethylamine, many beneficial materials. It is a mental faculties food as well as food to your pores and skin.
The benefit of Amino Acid L-Tyrosin for our brains
January 21, 2014 09:47 AM
L-Tyrosine is a nonessential amino acid because it can be made from phenylalanine, the another amino acid by our body. But from some researchers the body cannot make tyrosine from phenylalanine if stressed. In otherhand, L-Tyrosine is definitely present in many kinds of foods, such as milk, meats, eggs, nuts, cheese, bananas, beans and some seafood like fish.
Benefits of L-Tyrosine
By using this food stuff can increased the amount of L-Tyrosine in our body. And Also L-Tyrosine can we get from some suplement. L-Tyrosine has benefits for our brains. L-Tyrosine need for creating the neurotransmitters such as Dopamine, epinephrine and norepinephrine. It can called stress hormone. This compounds that transmit chemical signals in our brains. The neurotransmitters that was produced by L-Tyrosine have effect significant for your mood, memory, concentration, focus and alertness. The neurotransmitter Dopamine can affects the incentive mechanism in our brain which indicates it involved in feeling of happiness. Dopamine is also helps we keep motivated and handle problem that can make streesed. But too much stress can make our Dopamine level decreased. It can make our brain less active and weak. The neurotransmitter epinephrine ability to increases our energy, heart rate and breathing. It because epinephrine produces oxygen with rich blood that travels to our brain. Moreover the neurotransmitter epinephrine can boosting our memory, enhance cognitive performance, polishing our senses and reducing pain level of sensitivity. And the third compound of neurotransmitters is norepinephrine. It can helps increase our concentrate and to develop new memories. Norepinephrine is also travels through our blood and can stimulate our brains. The effect of our body does not produce enough neurotransmitters, we will become depressed, fatigued, confused and also develop memory loss. So if you want to enhance your memories and don’t let your body has less L-tyrosine to products stressed hormone that you need. Food supplements have shown good results in improving the amount L-tyrosine in our body.
What Is Vitamin B-6 And What Is Its Health Benefits?
January 05, 2014 09:19 AM
Vitamin B6 is a water soluble vitamin that is part of the vitamin B complex group that consists of pyridoxal (PL), pyridoxine (PN), pyridoxal 5 phosphate, pyridoxine 5 phosphate, 4-pyridoxic acid (PA), pyridoxamine 5 phosphate, and pyridoxamine. Pyridoxine is the form that is commonly given as a vitamin B-6 supplement. Vitamin B6 is also found in most multivitamin mineral supplements.
The benefits of vitamin B-6 include:
The amount of vitamin B-6 that is needed daily by the body depends on age and sex. Men and women between the ages of 19 and 50 need 1.3mg/day, women who are 51 years and older need 1.5 mg/day, pregnant women need 1.9 mg/day, and men over 51 years need 1.7 mg/day.
Below are some of the foods that contain vitamin B6 (the amount of vitamin B6 they contain is in mg)
Fruits- per carrot juice contains 0.27 mg per 125mls, prune juice contains 0.30mg per 125 mls. and one avocado fruit contains 0.26 mg.
Grains- 30 g of wheat bran contains 0.35 mg of vitamin B6, 30 g of bran contains 0.20 mg
Meats- 75 g of cooked beef liver contain 0.76-0.78 mg, 75g of cooked beef contains 0.14-0.26 mg, 75 g of salmon or tuna contain around 0.67 mg, and other fish (trout, cod, mackerel, snapper, bluefish, and herring contain 0.30-0.39 mg.
Legumes- 0.75 of a cup of soybean contains 0.30 mg, 0.75 of a cup of chickpeas contains 0.84 mg, and 0.75 of a cup of lentils contains 0.26 mg.
The symptoms and signs of vitamin B6 deficiency include:
anemia, depression, convulsion, irritability, morning sickness, and sore tongue.
You can easily meet your daily requirements of vitamin B-6 by taking vitamin B-6 supplements. Athletes who are taking protein and amino supplements should also take vitamin B6 supplements to improve their body’s intake of the proteins and amino acids consumed.
The Facts About Herb Dopa Mucuna
December 15, 2013 05:17 PM
What is Herb Dopa Mucuna?
Dopa Mucuna has become used as an aphrodisiac. Which is still used to raise and help libido in both women and men. However it's an alternative treatment peculiarity now is extremely popular used as it provides potential and valuable results in managing Parkinson along with conditions. Pots include seeds called velvet beans or mucuna beans, these are glowing brown or black. Dopa Mucuna is generally be able to recover soil fertility and decrease weed infestation. In society medicine seeds can be used healing different conditions and disease. Mucuna beans have been used as a coffee alternate (ground and roasted) in Brazil, Central America, and other countries.
The primary acts of the plant are following :
You've surely would not heard about L-Dopa, except if you are associated with somebody who carries body builder or Parkinson's disease, you might not be familiar with about it. L-Dopa is a precursor to Dopamine. The seeds of Mucuna bean is rich in lipids, protein, ash, dietary fiber, minerals, and carbohydrates. Moreover they are very high in sterols, alkaloids, and saponins. Mucuna seeds (along with the seeds of every Mucuna varieties) include high level of L-Dopa is an immediate precursor of the neurotransmitter Dopamine.
How does it works?
Low Dopamine ranges are related to psychosis, addiction, schizophrenia, depression, and Attention Deficit Disorder. Because Dopamine itself is unable to move the blood-brain barrier, it is transferred in a precursor condition is an outline that causes the brain to generate Dopamine. L-Dopa is simply like a precursor. L-Dopa is located to work in improving concentrate, relieving depressive disorders, and managing Parkinson's Disease.
Dangers of Rhodiola Rosea? First Lets Look at The Benefits
December 20, 2012 08:02 PM
Rhodiola rosea also referred to as golden root or roseroot grows in the extremely cold parts of the world. Although there are over 200 different species of roseroot rhodiola rosea is the popularly specie due to its health benefits. It is currently widely used in Asia and Europe to treat several health conditions.
Improves Depression and Mood
According to a study in the Nordic Journal of Psychiatry Rhodiola rosea extracts helps improve mood as well as lifts depression. It is also known to help improve sleep, lower moodiness as well as lift mild to moderate depression. It is known to help relieve fatigue on the patients suffering from stress associated fatigue. It not only decreases fatigue it increases mental performance particularly concentration and reduces cortisol production in people suffering from fatigue syndrome. It is therefore important to note that supplementation with rhodiola rosea robustly cancels out physiological and behavioral changes induced by persistent exposure to gentle stressors.
Functions as an Adaptogen
It is also a known adaptogen meaning that it helps in strengthening your endocrine and immune nervous system, thus improves your ability to defend against internal and external stress. It works a little different from other adaptogens such as ginseng, it works on neurotransmitters such as serotonin, norepinephrine and Dopamine which are associated with several illnesses such as seasonal affective disorders and fibromyalgia. It helps you to withstand stress as well as stress related diseases such as lowered immunity and hypertension. It has also been noted to increase the ability to exercise, reduces lactate levels as well as skeletal muscle damage mainly after vigorous exercise.
It is advisable that you consult your doctor before you start taking any rhodiola rosea supplement. Despite its numerous health benefits it has several negative side effects especially if high doses are consumed. The dangers include irritability, insomnia, dry mouth and dizziness. Pregnant women, breast feeding mothers and people suffering from manic depressive and bipolar disorders should not take rhodiola.
This Herb is considered generally safe for most individuals with many mood boosting properties.
How Curamin Combats Inflammation Pain
December 19, 2012 12:08 PM
Fact: You can manage pain with natural remedies!
Study has revealed the sad fact that four out of every five Americans perceive that pain is a natural inevitable part associated with old age. Athletes on the other hand believe that severe pain is essential for physical fitness. Many people again, think that there are certain disorders that ignite pain and you can do less or nothing to relieve the ache.
In fact, 28% of America's population believes that there is no solution that can eliminate their personal pain concerns. In the contrary, Curamin by EuroPharma is a highly effective herbal remedy that combines four powerful and clinically proven ingredients, into a single award-winning product that offers an ultimate level of pain relief.
Here is a look into how Curamin relieves inflammation pain.
#Curamin's Ingredients The secret behind Curamin's power is blending the best of the best. These ingredients are well known for their fast action in relieving pain associated with inflammation especially in the bones and joints. Here are the four main ingredients used in the formulation of this unprecedented pain reliever.
*DLPA (DL-phenylalanine) This is a double part amino acid (D phenylalanine & L phenylalanine) that impedes the breakdown of the enkephalin compound, also known as the positive mood enhancer. In addition to that, DLPA converts the L phenylalanine into tyrosine so as to enhance the secretion of two brain chemicals; norepinephrine and Dopamine, which ease pain and dissolve inflammation.
*Boswellia Boswellia serrata, also known as Indian frankincense is an anti-inflammatory herb used in the Curamin formula. The boswellic acids prevent the hyperactivity of an enzyme called lipoxygenase, which is often associated with inflammation. This way, it effectively combats inflammation pain.
*Nattokinase This natural ingredient is extracted for a Japanese fermented cheese known as natto, hence its name. The production of this beneficial enzyme can be attributed to a certain bacterium called Bacillus natto. Its benefits in relieving pain come through its action of breaking down clots, promoting the circulation of blood. Thickened blood can intensify pain, and by promoting blood circulation, all other Curamin ingredients are well distributed to every single part of the body.
*Curcumin This powerful, natural compound derived from turmeric requires no detailed introduction. It promotes the body's natural ability to combat inflammation and also contains anti-oxidant properties that are very useful in preventing tissue damage. Its functionality in pain relieving is behind its effectiveness in cutting off pathways that lead to inflammation. Numerous studies have also depicted its ability to promote cognitive-enhancing as well as anti-depressant benefits by igniting neuro-protective brain functions and moderating pain neuro-transmitters.
#How Curamin Relieves Pain
This proprietary formula combats inflammation pain by promoting the body's defense mechanism. In addition to that, it features curcumin BCM-95 which has an enhanced oral bioavailability and is highly soluble, thus availing a full spectrum or curcuminoids that fight pain in a flash. Additionally, the amino acids and Boswellia used in the formulation of Curamin helps the body to absorb the pain alienating ingredients quickly, which earns Curamin its well deserved fast-acting characteristic.
Curcumin BCM-95 has extended blood retention; one among the many attributes that makes Curamin stronger than other plain curcumin products. We cannot forget to mention the fact that Curamin is associated to no known side effects. It combats all types of pain ranging from occasional back pain to chronic pain caused by arthritis. So, next time pain becomes a problem, grab a bottle of Curamin and make your life a whole lot easier.
st johns wort and depression
October 10, 2012 12:10 PM
St. John's Wort
St. John's Wort, also scientifically known as hypericum perforatum, or Klamath Weed, is a herb with yellow flowers. It has numerous composition of strong compounds like hypericin and hyperforin thathave shown evidence of antibacterial, antidepressant, anti-inflammatory, anti-viral and antioxidant properties.
St John Wort can be used to treat mild session of anxiety depression and mood swings, the hyperforin chemical found in it, elevates the level of the neurotransmitters (Dopamine, serotonin) that relay information in between cell and play a vital role in the nervous system. The herb has the ability to inhibit chemical associated with anxiety and depression and thus induce a sense of wellbeing and help moderate depression, anxiety, mood swings, chronic fatigue and low energy level.
Other benefit of the St John Wort is that it can help treat hangover and alcoholism; it also helps prevent the risk of getting Parkinson disease. It antibiotic and anti-viral properties can help treat congested sinus or a chronic cough its antibacterial and analgesic propertied help to treat wounds and burn.
The Health benefits of P-5-P
July 20, 2012 07:51 AM
P-5-P or Pyridoxal-5-phosphate
P-5-P or the most commonly called Pyridoxal-5-phosphate is known to be the most active form of the Vitamin B6. This is known to be converted from organic compounds pyridoxal, pyridoxine and pyridoxamine. The Vitamin P-5-P is a coenzyme which support several other enzymes in the body which play a important role in biosynthesis. This also makes optimum use of the vitamin B6 by improving the body metabolism and many other biological process as well. The vitamin B6 traditionally comes in the form of pyridoxine hydrochloride which the body finds difficult to synthesize in its existing state. Hence, this pyridoxine hydrochloride is processed and is formed as Pyridoxal-5-phosphate to help the body to use the vitamin B6 effectively.
There are a lot of benefits of the vitamin P-5-P
Let us have a look at some of them.
Pyridoxal-5-phosphate uses the information from the genes ad helps to produce proteins.P-5-P is also helpful in the formation of hemoglobin, histamine and neurotransmitters and is also helpful in the metabolism of amino acids, fats and glucose.Pyridoxal-5-phosphate also helps in the conversion of Dopa which is a useful substance used in the treatment of Parkinson's disease. Dopa is converted to Dopamine which is a neurotransmitter which is produced in the brain and is released by the hypothalamus.
The P5P is also helpful in the utilization of the food sources for the formation of energy and also helps in the easy release of glycogen which is the stored energy.P5P also converts glutamate into GABA which is gamma amino butyric acid which is again a neurotransmitter which is known to be found in the mammals. This is found in their central nervous system.The Pyridoxal-5-phosphate also helpful in the process of decarboxylation which is the conversion of histidine to histamine.
This also converts SAM-e to propylamine which is known to be a precursor of polyamines.The Vitamin P5P is also responsible to lower the homocystenie levels which are caused by the intake of high amounts of methionine.The Vitamin Pyridoxal-5-phosphate helps in the treatment of irregular heartbeat , which is a condition termed as arrhythmia.This plays a important role in the treatment of myocardial infections. This prevents the blood platelets from sticking to each other which usually causes blood clots.The enzymes produced by the Pyridoxal-5-phosphate also helps in the formation of different kinds of amino acid reactions which keeps the carbon ions stable. This process is very important in the metabolism of the cells.The P5P also helps in the metabolism of the amino acids.
Here it helps in converting methionine to cysteine and also converts tryptophan to niacin.Pyridoxal-5-phosphate also plays a vital role in the formation of glucose. This process is known as gluconeogenesis.This also acts a important co-enzyme in the process of glycogenolysis which happens in the liver and muscles and this is known to be a reaction which occurs due to presence of glycogen.The P5P also helps in the formation of antibodies and also assists in the process of hemoglobin synthesis as well.
To keep it simpler, the vitamin P5P performs many functions which is very beneficial to the whole human body. The P5P deficiency can also happen in many individuals and even such symptoms are hard to identify. Any person suffering from the P5P deficiency will have symptoms like muscle weakness, irritability or depression. Consulting a physician and taking necessary supplements will help to overcome the P5P deficiency.
How Does GABA Help Brain Function?
May 16, 2012 08:43 AM
Gamma Amino Butyric Acid, GABA, is a neurotransmitter found in central nervous system. It has an inhibitory action on nerve transmission and helps in regulating brain activity and function.
Healthy functioning of brain is important to achieve optimal health. In today's fast paced lifestyle, work related stress and anxiety have taken a toll on man's health. Mental stress and anxiety can cause havoc on the internal systems of the body. According to American Psychological Association, stress can affect the physical as well as mental health of a person. It impairs the brain's ability to block certain toxins and can lead to certain aging conditions such as diabetes, cardiovascular diseases and cancer. Stress can affect brain's normal functioning and affect intellectual abilities and memory. GABA helps in calming the stress and thereby enhancing the functioning capacity of the brain. Let us understand how does GABA help in brain function?
Role of GABA in cerebral cortex:
The nervous system comprises of neurons, brain, spinal cord and neurotransmitters. The role of neurotransmitters is to transmit nerve signals from one neuron to another or from neuron to muscle or gland cell. The most abundant neurotransmitters in cerebral cortex, Glutamate and GABA, have opposite action on the neuron cells.
Glutamate is an excitatory neurotransmitter, which results in neuron fires and sends an electrical impulse down its length. On the other hand, GABA, made from glutamate, has inhibitory action on the nerve cells and does not allow the electrical impulse to pass through the neuron. In case of deficiency of GABA, nerve cells will fire too often and too easily, resulting in wide number of anxiety disorders such as panic attacks, seizure disorders, headaches and other cognitive impairment disorders. Hence, GABA helps in stopping the transmission of nerve impulses from one neuron to another and thereby regulating brain activity. It has a calming effect on the brain.
Once the activity in the brain is regulated and cognitive abilities are restored by GABA, the person can think better and perform better. This natural tranquilizer allows your brain to function more efficiently. Studies have related many higher brain functions such as visual recognition and language comprehension with declining levels of GABA with advancing age. This results in easy firing of neurons by stimulus, slowing down processing of information in brain.
Health benefits of GABA:
According to studies, GABA plays an important role in healthy functioning of mind and body. It helps in:
1. Treating conditions like depression, anxiety, Attention Deficit Hyperactivity Disorder and epilepsy. The result is due to the calming effect of GABA on brain activity. It helps in clear thinking and better reasoning.
2. Preventing age related conditions such as cardiovascular disorder, diabetes and cancer.
3. Inducing a sense of relaxation by providing tranquilizing effect. GABA increases Dopamine hormone in the body and gives a sense of euphoria. You remain happy and of course this has a positive effect on sexual system.
4. Relieving pain.
5. Promoting body building and losing extra fat.
GABA can be purchased as a supplement in the form of pill, capsule or powder form. It is a natural alternative for relieving stress and improving brain function.
How Does Phosphatidyl Serine Improve Your Health?
April 17, 2012 07:22 AM
Health Benefits Of Phosphatidyl Serine
Phosphatidyl serine is phospholipid that is vital to your brain functioning. The phospholipid are molecules containing both fatty acids and amino acids found in every cell in the body. Phodphatidyl Serine supplements are plant extracts that has been proven safe and effective therapeutic substance in remedying memory disorders as well as in enhancing higher brain functions. Clinical trials have shown that this vitamin supplement do strengthen your memory, increase mental acuity, increase concentration, boosts learning, enhances attention and vigilance. In addition, Phodphatidyl serine relieves depression while improving your mood and inhibits increases in cortisol induced by exercise and stress.
The supplement works by enabling your brain cells to metabolize glucose and releases it to bind with neurotransmitters which hence support learning, memory and other cognitive functions. Phodphatidyl serine enhances the cells communication in the brain through increasing the number of membrane receptor sites. It is also important to note that this natural supplement modulates the fluidity of the cell membranes which are essential in supporting the ability of brain cells to send and receive chemical communications.
Another health benefit associated with Phodphatidyl serine is its ability to restore the supply and output of acetylcholine in the brain. Acetylcholine is an essential transmitter to memory and is associated in reversing aging. Further, it increases the availability of endogenous chlorine used for de novo synthesis and production. Patients diagnosed with clinical depression that have ben put under the treatment of Phodphatidyl serine have registered a remarkable improvement with their symptoms. This follows from the fact that the supplement stimulates the production of Dopamine by the brain. A deficit in Dopamine in the brain has also been associated with attention deficit disorder and hence the natural supplement of Phodphatidyl serine has demonstrated to be an effective remedy for the disorder.
Research indicates that athletes involved in weight training, endurance running and cycling can reduce muscle soreness when they use Phodphatidyl serine. The athletes on this supplement have also been reported to undergo speed recovery during their rigorous training sessions. Other benefits of the supplement include; testicular function, formation of bone matrix, heart beat coordination, cell repair and removal by the immune system and secretion of hormones by the adrenal glands.
It is vital to note that phodphatidyl serine is present in almost every cell in our body and the membrane proteins it activates are important in all these cells. However, our bodies cannot produce enough amounts of it when under stress, when there is a deficit in necessary enzymes and metabolic cofactors, and when aged. Stress increases the demands for phospatidylserine thus depleting the available levels in the cells. On the other hand, aging not only increases the brain's requirement for phosphatidylserine but also leads to inefficiency in the digestive and metabolic functions of the body. This makes it difficult for aged people to acquire enough of it from the diet and thus it is recommended that aged people should use phosphatidyl serine supplements.
Modern diets with low fat and low cholesterol levels have been shown to be lacking in phodphotidyl serine to levels of up to 150 mg per day. A vegetarian diet on the other hand may have a deficit of up to 250 mg per day. This deficit in supply of Phodphatidyl serine in the diet leads to impairment of your brain's ability to form, store, process and even remember. It is vital hence to consider taking vitamin supplements with phosphatidyl serine to cater for the deficit which may be detrimental to your health.
What Makes Curamin Such A Good Natural Pain Remedy?
March 07, 2012 06:57 AM
Curamin: A Natural Anti-Inflammatory
When nerve endings become irritated, they cause pain. This is because of factors such as lack of sleep, hormonal imbalance, stress, nutritional imbalance, etc. Pain is generally symptomatic of some dysfunction or inflammation in our body and the first reaction for those suffering from it is to reach out for a pain killer. This is where Curamin comes in.
Curamin is a proprietary formula and a curcumin based supplement. Curcumin is a beneficial compound found in turmeric, a popular Indian spice. Turmeric has been used since centuries in the field of alternate medicine like Ayurveda because of its many medicinal properties. The compound, curcumin in fact, has the ability to reduce pain by supporting the body's ability to respond to swelling and inflammation. It has been found equivalent to some popular allopathic pain killers. Apart from this, it also has antioxidant, antibacterial, antiviral, antifungal and anticancer properties and has been found to promote anti depressant and cognitive enhancement benefits.
Curamin is a product having a formula based on this particular compound of turmeric and is therefore extracted out of natural ingredients and has been found to have minimal side effects. Curamin, apart from other ingredients, also contains a strain of curcumin that has a high absorption factor which makes it several times more effective and stronger than plain curcumin products. It not only balances the body's response to inflammation but also has been observed to have a consistent and long lasting effect. Therefore, this makes curamin the most effective form of curcumin available.
Studies have established that curamin is safe and does not interfere with kidney, liver or stomach functions. The safe dosage recommended by the company is two pills twice a day for pain alleviation and not more than 8 pills within a 24-hour period. An overdose of such herbal products may sometimes cause intestinal discomfort at the most.
Main Ingredients of Curamin
Curamin has four principle ingredients that have an overall effect on inflammation caused in the bones and joints due to arthritis or overuse and exercise. These ingredients include: DL-phenylalanine or DLPA is a two part amino acid that acts as a positive mood enhancer by preventing the breakdown of enkephalin compound and also helps in the production of brain chemicals like Dopamine and norepinephrine. Boswellia that helps to prevent the activity of the inflammatory enzyme. Curcumin which helps block multiple pathways within the body to retard and stop inflammation. Nattokinase which is an enzyme that helps the fast absorption of the ingredients through the body by promoting blood flow and improving circulation.
Benefits of Curamin
Curamin has helped people suffering from problems like arthritis, migraines, bursitis, and soreness caused by accidents or injuries. It also helps build resistance and immunity to inflammation concerned especially with the bones and joints.
Curamin, being a plant based product has no toxic effects and is available with many natural medicine practitioners and pharmacies. It is a very effective natural alternative to allopathic drugs and painkillers that over a long term use cause many side effects, some of which are potent.
If you are in pain, try curamin today!
What Are The Health Benefits Of Rhodiola Rosea?
February 26, 2012 07:02 PM
Rhodiola rosea is medicinal herb that has many beneficial health effects on humans. It grows in the cold regions of the world like Europe, Central Asia and Arctic region. The phytochemicals present in this medicinal plant are good antioxidants and they are quercetin, chlorogenic acid, gallic acid and proanthocyanidins. It also consists of essential polyphenols namely rosiridin, rhodioniside and rhodiolin in the extracts of Rhodiola. These substances are the active ingredients of this herb and helps in improving the overall health of the body. The extracts of this plant can be taken in the form of tea, pills or liquid form and must be taken after prescription by medicinal health expert.
Some of the health benefits of Rhodiola rosea plant are explained as follows
Stabilize the Nervous system: This nature gifted herb is very helpful to stabilize the levels of neurotransmitters in our brain and thereby increase the levels of tryptophan, Dopamine and norenephrine in our body naturally. Thereby, improve the neuro-chemical reactions inside the body.A Good Anti-oxidant: It acts as a good antioxidant and also protects our nervous system. It helps to overcome the damage caused to nervous system by eliminating the free radicals present in our body.
Treat Depression: It is known though a scientific research that Rhodiola rosea gave good results to treat mild and moderate depression on people of age group from 18 years to 70 years. The prescribed dosage to get the complete health benefit is 340 mg to 680 mg per day. SHR-5, the extract of this plant enhances the mental performance and also helps the person to concentrate on healthier subjects. This medicinal herb can also be used along with other anti-depressant drugs as it has the synergistic effect. Regular intake of the plant's extract according to the prescribed dosage by expert doctor reduced the symptoms of fatigue and helped them improve their concentration power. This herb is being used in cold counties like Scandinavia and Russia to overcome the stressful life and chill climate. Improves the Overall Health: This medicinal herb is known to enhance the immune system of a person and also improve the overall health. It helps in preventing the side-effects of stress and improve the physical activity, enhance the mood, appetite, estrus cycle, reduce fatigue etc.
It also helps to overcome stress, anxiety, anemia, hormonal imbalance cardiovascular diseases, and neurological disorders of a person. It is also known to decrease the time needed for recovery after any strenuous muscular activity.
Treat Insomnia: It is also being used to treat Insomnia and has given good results. Sleeplessness can be cured effectively with this herb without any side effects. Pregnant women and breastfeeding mothers should not take this medicinal herb as it has some side effects on them.
Always consult your medicinal health expert before taking the extracts of this herb and take the correct dosage.It is known to maintain creatine phosphate at high levels and this is especially useful for athletes to maintain their stamina levels. Rhodiola rosea is also used to overcome the side effects of radiation therapy and chemotherapy.
Chaste Berry a Women Herb
February 08, 2012 11:51 AM
Other names of Chaste Berry- Monk's pepper, Chaste-tree Berry
Chaste Berry is the fruit found on Chaste tree which is botanically known as Vitex. Chaste tree is a decidous tree that grows in a well-drained, acidic soil in full sun. Vitus agnus castus or Chaste Berry is a native to the Mediterranean and Central Asia but now is grown throughout the world. The tree belongs to Verbanaceae family and can grow to a height of 22 feet. It was traditionally used by men in ancient Greece and Rome to reduce sexual desire, treat menstrual disorders and other hormonal problems and as an anti-microbial agent against infections. It is also known as 'Women's Herb' as it regulates hormonal imbalances and promotes women reproductive health. Aside from its medicinal use, it was used as a peppery condiment. Some of the constituents included in Chaste Berry fruit are flavonoids (casticin, orientin, isovitexin, kaemferol), glycosides (aucubin and agnuside) and essential oils (linalol, sabinene, pinene and limonene). These phytohormone compounds help in regulating the female hormones production and normalising testosterone and progesterone activity.
Effects of Chaste Berry:
ChasteBerry controls and regulates overall female reproductive system.
1. It helps to manage Pre-Menstrual Syndrome: Pre-Menstrual Syndrome is associated with several uncomfortable symptoms, ranging from mood swings to fatigue and hot flushes. Chaste Berry is known to be rich in progesterone that helps to ease out the disturbing symptoms of Pre-Menstrual Syndrome.
2. It helps to normalize menstrual irregulaties: Imbalance in prolactin levels in the body can lead to various complications in women such as amenorrhoea (absence of periods), breast tenderness and reduced milk production in lactating mothers. Chaste Berry balances natural production of prolactin hormone in the body and effectively treats menstrual irregularities and other symptoms such as tenderness of breast and reduced milk secretion.
3. It treats menopausal discomforts: Some women experience dicomfort and other menopausal symptoms that affect their daily routine life. The hormone regulating properties of Chaste Berry help in easing menopausal symptoms such as mood swings and hot flushes and several other physical symptoms associated with hormone deficiency during menopause.
4. It improves overall female reproductive health: Chasteberry has been found to be effective in treating fibroid cysts especially of smooth muscle. It also reduces heavy bleeding associated with perimenopause.
5. It helps in treating Hormonal acne: Hormonal acne are due to imbalance in androgen hormone levels. Increased androgen levels in the body leads to excessive sebum production that causes acne. This wonder herb regulates the androgen levels in the body and thereby helps in treating moderate and light acne. Another way in which this herb prevents acne formation is its anti-bacterial property. The bioactive essential oils present in Chasteberry have anti-bacterial properties that prevent the survival of bacteria. Chaste Berry contains linoleic fatty acid which is responsible for regulating sebum production.
Chaste berry modulates the hormone prolactin with the neurotransmitter Dopamine. The active ingredients such as polyphenols in the herb indirectly affects hormones and neurotransmitters and regulate the hormones.
Chaste berry herb is a safe and natural treatment for many women related problems.
Grape Seed or Pine Bark Extract, Which Is Best?
October 27, 2011 07:26 AM
Pine Bark Vs Grape Seed Extract
Pine Bark Extract and Grape Seed Extract are two well known products that are effectual in combating ADD. Pycnogenol however, is more expensive since it is a patented form of pine bark extract that is being sold in many health stores world-wide. The potent properties of both Pycnogenol and Grape Seed Extract are their proanthocyanidins or flavan-3-ols contents that are normally found in fruits and vegetables. The reason why these chemicals are beneficial is their capacity in aiding vitamin C to work better for the brain. Vitamin C is essential for the production of norepinephrine, serotonin, and Dopamine (neurotransmitters involved in ADD). Vitamin C is also useful in providing the body with antioxidants that can help fight free radicals that are very injurious for your health and may lead to a dreadful disease such as cancer. In addition, another role of vitamin C in the body is its capacity to aid the body in chelating detrimental toxic heavy metals by flushing them out from the body.
Pine Bark Extract and Grape Seed Extract are also effective natural anti-histamines anti-inflammatory agents and immune boosters. Both extracts are also proven to be influential in terms of regulating enzymes that have significant effects in metabolism. Since the extracts are able to inhibit the breakdown of Dopamine and norepinephrine, then it will also lead to a faster reuptake of Dopamine.
Proanthocyanidins has been the subject of interest by many researchers in the scientific investigations that they have conducted because of its promising effects that could treat various venous conditions. The compound has been proven to be effectual in strengthening the walls of your capillaries, arteries and veins hence, is very useful in protecting you from ailments that involves the mentioned vital body parts.
The benefits of Pine Bark and Grape Seed are already published in many health magazines worldwide as well as in many TV shows like the 60 minutes. The antioxidant content of the extracts derived from Pine Bark and Grape Fruit contains liberal amounts of antioxidants that also acts as an antimugenic agent hence, could prevent DNA mutation. Since the extracts have such innate capability of inhibiting the mutation of DNA, it can be a cure to many chronic degenerative diseases that are caused by environmental mutagens.
Another benefit of OPCs is its relevant effects on peripheral venous insufficiency. This specific problem in the legs causes so much pain and discomfort which could also lead to disability. With OPC, relevant improvement in the condition could be noted as evidenced by a decrease in the pain felt, edema and cramps.
Comparing both extracts in terms of efficacy is so difficult to determine because Pine Bark Extract and Grape Seed Extract has similar components that are all beneficial to one’s health. The compounds that both extracts have are very useful to one’s health therefore comparing the two would be rootless considering all the health benefits that both extracts could offer.
Can Royal Jelly boost Metabolism?
September 21, 2011 12:08 PM
The metabolism is becoming more and more well known in any community all across America as something to look at when we are talking about health and wellness as this is the source of all calorie burning and at the end of the day will help you lose weight. This is, in so many ways the bottom line, losing weight will make you and keep you healthy. In these times of a fast paced life where anyone and everyone is so busy to even worry about how much calories they eat versus how much they need, a need for alternative solutions aside from just working out and making sure that more calories are burnt than eaten is needed and the scientific community acknowledges that need as proven by the tons of research done regarding weight loss and embraced by the manufacturers as they are more than willing to provide us with what we need. So through all these studies, the logic of looking at the metabolism and how to boost it all seems natural and this is why.
The word metabolism is taken from the greek language and basically means change or transformation. In simple terms metabolism is defined as the amount of energy or calories your body burns at a given period of time. Whatever we are doing, no matter if we are active or at rest we are burning energy and if compared to a car, it’s like burning fuel and the car can be turned off but us on the other hand could not. Even when sleeping we are still essentially burning up fuel, just the very fact our brain still works and we are breathing while we are asleep is already a sign that we are burning energy.
Now where it will interest us in terms of energy and overall strength is that metabolism is based on a person’s body composition and fat tends to need less energy to maintain itself as it is not an active tissue compared to having lean muscle because it continually needs more and more calories to maintain itself therefore more muscle means faster metabolic rate. Now this is where we go back to the fact that we need help when it comes boosting metabolism aside from just increasing muscle, because that is so much harder than supplementing with something all natural like Royal Jelly.
Royal Jelly and Energy Boost
Royal jelly is an animal product and derived solely from honey bees secretions. Its main function in terms of affecting the metabolism comes from its unique combination of compounds that will aid the enhancement of energy production in the cells. This combination is composed of amino acids, trace minerals, monosaccharides and enzymes that have bioactive properties. Among the vitamins that it will provide naturally is the vitamin b-complex. This family of vitamins is well known for its muscle tissue building and energy boosting attributes. Another way that researches feel is a way it increases energy is through promoting overall well being since royal jelly has been related to increased production of several neurotransmitters in the body like serotonin and Dopamine.
What Vitamins And Minerals Are For Mental Alertness?
August 29, 2011 10:33 AM
There are many vitamins and minerals which can help improve the health and functioning of the nervous system. Vitamins and minerals are significantly involved in many biological processes of the body. It influences the activities of the organs of the body including the brain. In fact, deficiencies on vitamins and minerals may result to psychological or even psychiatric symptoms in certain individuals. People with psychiatric problems are also prescribed with vitamin and mineral supplements which serve as one of its conventional treatment.
The vitamins and minerals which are good for the improvement of brain function and improvement of mental alertness are the following:
1. THIAMINE OR VITAMIN B1. Generally, insufficient amount of this enzyme may result to mild psychiatric symptoms. Studies revealed that people with inadequate amount of this vitamin has the symptoms of fearfulness, anxiety, depression, agitation and behavioral instability. This vitamin is necessary for the activity the body’s enzyme called pyruvate dehydrogenase. This enzyme is required for the conversion of pyruvate to acetyl – coenzyme A. If pyruvate is not catalyzed into acetyl – coenzyme A, the excess pyruvate in the body might be converted into lactate which can cause muscle pains and also psychiatric symptoms such as anxiety. Deficiency of this vitamin must be suspected when the person is alcoholic or malnourished.
2. RIBOFLAVIN OR VITAMIN B2. This vitamin is closely associated with major depression in relation to oxidative stress. Riboflavin is required for the metabolism of protein, fats and carbohydrates. The building blocks of these macronutrients are important for the maintenance of brain health and proper functioning of the nervous system. It can improve the energy levels and functioning of the brain, thus improving an individual’s mental alertness.
3. PYRIDOXINE OR VITAMIN B6. Studies show that low level of vitamin B6 is directly related to depression. Inside the body, pyridoxine is converted into its biochemical active form called pyridoxal phosphate which is important for mental alertness and brain functioning. Pyridoxine acts as a coenzyme involved in the synthesis of brain chemicals such as serotonin, Dopamine and gamma aminobutyric acid (GABA). This vitamin is also involved in the metabolism of carbohydrates and amino acids which are essential for boosting energy levels.
4. COBALAMIN OR VITAMIN B12. Deficiency of this vitamin is closely related to decrease mental functioning. Vitamin B12 is a cofactor of the enzyme methionine synthase which is important in the conversion of homocysteine to methionine. This is required for the production of energy in fatty acids and proteins which is important for the methylation reactions of brain chemicals.
5. VITAMIN C. This vitamin is considered to be a cofactor of the neurotransmitter Dopamine and is involved in the conversion of Dopamine to norepinephrine. These brain chemicals are important for the maintenance of proper mental alertness.
6. FOLATE. Decreased mental alertness and depression is a common symptom of low levels of folate in the body. This mineral is involved in the methylation and synthesis of DNA. It is important for the development of brain function and improvement of mental alertness.
7. MAGNESIUM. This mineral is involved in many reactions of the body. Individuals with decreased mental alertness are found to have low levels of magnesium in their cerebrospinal fluids.
8. ZINC. This is a mineral which is important in the catalyses of many enzyme sin the body. It is found in high amount in the brain which is important for nervous activities.
Why Is The Amino Acid Tyrosine So Good for the Brain?
June 18, 2011 12:20 PM
Tyrosine is an amino acid that serves as an immediate precursor to several organic compounds found in the brain and the central nervous system. It is one of the 20 amino acids utilized by cells in protein synthesis. As such, it is an important component of the human diet, albeit not classified as an essential nutrient. Mental infirmities not related to age has been linked to tyrosine deficiency.
There is no daily value for tyrosine, but it is an integral part of proteins obtained from both animals and plants. Also, supplementation of tyrosine has not shown any adverse effects. That being said, deficiency in tyrosine is not unheard of. In fact, there is a rare autosomal recessive disorder called phenylketonuria that interferes with the synthesis of tyrosine and leads to brain damage and seizures.
Prevents Brain Damage
Tyrosine is one of the amino acids necessary for the manufacture of neurotransmitters and proteins that display vital functions in the nervous system. In phenylketonuria, the synthesis of tyrosine from phenylalanine is impaired, causing the build-up of the latter. High concentrations of phenylalanine deprive the brain of other amino acids, such as tyrosine. This results in progressive mental retardation.
The presence of tyrosine in the central nervous system is very important in mental development. It works as nutrient for nerve cells that powers neuronal activities. Not surprisingly, regular intake of tyrosine has been observed to display cerebroprotective properties. It has also been linked to the prevention of headaches following an intense physical activity.
Improves Stress Tolerance
It has long been suggested that supplementation of tyrosine may improve stress tolerance, but studies that support this claim have surfaced only recently. High levels of tyrosine in the brain appear to improve physiological responses to stress in both animal and human studies. Many researchers believe that depleting levels of tyrosine in times of stress contribute to mental fatigue.
Tyrosine is a precursor to catecholamines, organic compounds that function as neurotransmitters and hormones. It is converted to epinephrine, or adrenaline, which is responsible for the activities in the peripheral nervous system during stress. It is also converted to norepinephrine, which sends signals to both sides of the brain and forms a neurotransmitter system within the brain and the spinal cord.
Promotes Mental Clarity
Tyrosine plays a role in sustaining mental clarity, the reason why it is thought to produce nootropic effects. For one, the availability of tyrosine in the brain improves mental function, especially under psychological stress. It is utilized by the brain in the manufacture of brain chemicals involved in cognitive function and even motor skills.
More importantly, tyrosine provides a ready pool of levoDopa, which increases Dopamine levels. Both tyrosine and Dopamine levels have been observed to be low in individuals suffering from clinical depression, suggesting that tyrosine may provide mood-altering effects. Since there is no harm in regular intake of tyrosine, it has been promoted as an alternative to other mood enhancers.
Can Royal Jelly Really Boost Energy?
April 18, 2011 02:25 PM
Royal Jelly as an Energy Boost
Royal jelly is an all-natural animal product entirely derived from the secretions of honey bees. It is commercially touted as an energy booster because of its unique combination of compounds that help produce energy in cells and promote mental clarity. It contains an abundance of monosaccharides, amino acids, fatty acids, trace minerals, and enzymes, all of which have bioactive properties.
Inside a honeycomb, royal jelly is obtained from queen cells. These secretions are actually fed to all larvae, but only queen larvae are fed with royal jelly in amounts that can be harvested. This is the reason why royal jelly is considered rare. That being said, recent innovations in the manufacture of honey and the overall beekeeping process have contributed to increasing productions of royal jelly.
Contains Vitamins and Minerals
Royal jelly is available as a dietary supplement noted for its high vitamin and mineral content. It is a natural source of vitamin B complex, notably pantothenic acid (vitamin B5) and pyridoxine (vitamin B6). It has relatively high amounts of simple sugars and fatty acids, both groups are biological precursors of cellular energy. In general, it contains up to 15 per cent carbohydrates and 5 per cent healthy fats.
In addition to vitamins, it is also rich in enzymes that are believed to aid the fast absorption of its bioactive compounds in the small intestine. In addition, it contains trace amounts of dietary minerals. Royal jelly is often marketed as a fast-acting energy booster because its components are believed to work synergistically in the prompt release of energy within cells right after absorption.
Improves Energy Metabolism
Coenzyme A is an organic compound produced in the human body to aid the metabolism of cellular energy. Its synthesis, however, requires the presence of pantothenic acid, a vitamin obtained largely from the diet. It is postulated that royal jelly helps increase the production of energy in that it contains pantothenic acid in amounts sufficient to affect the biosynthesis of coenzyme A.
Royal jelly is also noted for its pyridoxine content. Pyridoxal phosphate, or pyridoxine, is the active form of vitamin B5. It is necessary for the metabolism of protein, glucose, and lipids. It is of special significance in yielding energy from glycogen, which it converts to glucose. The combination of fatty acids, simple sugars, and B vitamin in royal jelly enables it to bring about a noticeable energy boost.
Creates Feelings of Well-being
Royal jelly has been linked to an increase in the release of major neurotransmitters, especially serotonin, Dopamine, and glutamate. Serotonin is dubbed the happiness hormone. Dopamine is linked to rewards-seeking behavior and keeps interest in repetitive tasks. And glutamate is a major excitatory neurotransmitter in the central nervous system. Together they sustain mental focus.
The roles of its components and their metabolites in the production of energy and release of brain chemicals are the reason why royal jelly creates feelings of physical and mental well-being.
Royal Jelly Use It
As you can see, royal jelly is rich in many nutrients to support a health brain and metabolism. If you are seeking more energy, give royal jelly a try!
A Good Vitamin Plan Is Essential To a Health Child To Help Fight ADHD
December 21, 2010 06:19 PM
Have you known any child who is having difficulty staying focused and paying attention, difficulty controlling behavior, and hyperactivity or over-activity? This child is probably experiencing attention deficit hyperactivity disorder or ADHD. ADHD is a common childhood disorders and can continue through adolescence and adulthood. Researchers are not sure what causes ADHD, although many studies suggest that genes play a large role.
Like many other health conditions, ADHD probably is a result of a combination of factors. There has been no cure for ADHD yet palliative management is promising in reducing symptoms of ADHD and improving the child’s well being and optimal functioning. These include medications, psychotherapy, training and education or a combination of these managements. In this article, we will be focusing on the natural vitamins that can help fight the exacerbation of ADHD symptoms which include:
1. Choline: Choline is a vital precursor to the production of neurotransmitters such as Dopamine and Acetylcholine. These nervous system chemicals are helpful in supporting concentration, alertness, and memory.
2. Zinc: Studies show that children in ADHD categories have lower levels of zinc and clincal studies reveal that those children who supplemented with extra zinc along with traditional ADHD medications have reported improvement of signs and symptoms most especially hyperactivity and impulsivity. Foods high in zinc include Seafood, oysters, salmon, crabmeat, and, red meat like beef, lamb and pork, poultry such as turkey and chicken, dairy products, nuts, beans, fortified cereals, and whole grains.
3. Fish oil: Most Oily Fish contain omega-3 fatty acids With DHA. These chemicals can improve mental skills and enhance the child’s ability to organize activities. Possible cause for the low fish oil status of the ADHD children may be impaired conversion of the fatty acid precursors namely Linolenic Acid and alpha-linolenic acid to their longer and more highly unsaturated products, EPA and DHA, which are fish oil fats. Fish high in omega 3 fatty acids include salmon, albacore tuna, herring, mackerel, trout, sardines, flax seeds, walnuts, butternuts and soybeans.
4. Magnesium: Magnesium can have a calming effect. The best thing about magnesium is that it is abundantly found in many foods. Low dietary magnesium levels could lead to anxiety, irritability, and/or restlessness. This mineral can also play a role in sugar metabolism, which is important when wanting to stabilizing moods and concentration. Magnesium, a calming mineral, can be found in foods like nuts, black beans, peas, seeds and ready-to-eat whole grain cereals.
5. Vitamin B-6: Vitamin B-6 is needed for normal mental development and is important in the synthesis of brain chemicals including Dopamine , serotonin, and norepinephrine. A B-6 deficiency has symptoms of inability to concentrate, irritability, and short-term memory loss. Regular consumption of vitamin B-6 could help reduce behavioral issues in a ADHD child. Good sources of B vitamins are milk, fish, eggs, yeast, green-leafy vegetables and cereals. Oranges are a great source of vitamin C and can improve our mood.
These are some of the natural vitamins that we find in our food. A good multiple vitamin supplements with iron can be safe and effective.
If you Suspect your child has ADHD, whats stopping you from getting him or her on a supplement plan today?
Fight Anxiety Disorders Naturally
December 14, 2010 04:27 PM
Do you suffer from an Anxiety Disorder?
Before considering how to test for anxiety disorders and discussing natural supplements that can help we should first discuss what anxiety disorders are - what the term means and if there are degrees of anxiety disorders as there are of depression and stress. First, what is anxiety?
Anxiety is a natural reaction to stress and it is anxiety that makes you worry about the consequences of not studying for an exam - so you study. It focuses you on problems so that you will be more likely to solve them, and helps you to perform better whatever you are doing. However, it can get out of hand and these positive mental processes become negative anxiety disorders.
With some people, anxiety becomes a dread of situations that were once everyday occurrences and can make your life a misery. Here are some forms of anxiety disorder.
Typical Anxiety Disorders
General Anxiety Disorder
Its symptoms include excessive sweating, worry, headaches, irritability, difficulty in sleeping, tiredness and tension in your muscles. It can lead to substance abuse and deep depression if left untreated.
These are three typical forms of anxiety, but how do you test for anxieties? Here are some tests that are used, beginning with the easiest - doing it yourself!
Testing for Anxiety Disorders
Many that believe they may have an anxiety disorder either tend to panic or go into a depression. It is far better to carry out a self-test. This anxiety test is very simple: simply tick which of the symptoms below you have experienced in the past six months:
I can't relax
I am always worried about something.
I get headaches for no apparent reason
I frequently sweat a lot and get hot flashes
I have no time for anybody and am easily annoyed
I find it hard to sleep and I often wake up during the night
My attention keeps wandering and I can't focus on anything
I sometimes get so worried I want to be sick or have a lump in my throat
If you have ticked more than three then perhaps you should pay your doctor a visit, or try some of the recommendations below.
b) Doctors' Tests
If you feel you might be suffering some form of anxiety disorder you should consult your doctor, particularly if you have tried the self test above and it indicates that you might be. Your doctor might carry out various tests for your general health, and if it is felt necessary you may be asked about your family history: is there any history of mental problems in the family, particularly with your mother or father.
Other questions may appertain to your own physical and mental background, such as have you been stressed for any reason lately, have you suffered anxiety or panic attacks in the past and what is your normal use of prescription and non-prescription medications and drugs. Do you smoke, drink or take any social drugs.
It is important that you are totally honest: the doctor is not judging you, simply trying to find the cause of your problem. Under the terms of their oath they cannot divulge anything you tell them to anyone else, so be honest and let them help you. Among the tests you will be given will be to declare all your history of anxiety-related symptoms. To achieve that, you will be asked a series of questions while the doctor assesses your mental condition.
Finally, you may be referred to a psychiatrist who will be able to help you more than your doctor. Psychiatrists have a good record in resolving anxiety disorders, but once you are diagnosed positively, what then? Chemical drugs? Or perhaps you would prefer something more natural such as herbal remedies.
Herbal Remedies for Anxiety
There are a number of herbs that can be used to treat anxiety disorders. Here are the more commonly used of these:
Passion flower contains the active substances maltol and ethylmaltol that your body's biochemistry uses to increase the concentration of GABA (gamma-butyric acid) in your brain. GABA is a neurotransmitter that calms you and helps you to relax and forget anything that is making you anxious. It relieves muscle tension, can lower your blood pressure and some equate its effect to that of Valium: although it is totally different chemically it is similar in its effect. It offers a sedative effect and helps you sleep.
Kava Kava root
Kava kava. Generally just referred to as kava, comes from the Pacific and the kavalactones it contains increase the concentration of neurotransmitters in your vascular system, particularly serotonin, the feel-good substance. Its sedative effects have been likened to that of alcohol, and it can certainly give you a lift and certainly helps you worry less as it reduces the negative symptoms of stress and depression.
St. John's Wort
St. John's wort is a well-known anti-depressant and it can also help reduce the symptom of anxiety. The hyperforin the plant contains helps to improve the brain's content of the neurotransmitters serotonin, Dopamine and norepinephrine that make you feel good, and St. John's wort certainly washes away your anxiety. Not only that, but the napththodianthrone in another of its important components, hypericin, promotes a reduction in depression through the inhibition of monoamine oxidase, a pro-depressive enzyme.
An extract of valerian root can help you to relax and sleep well, and this can often be enough to prevent your anxiety attacks. A lot depends on their cause, but if the attacks are mild and don't require extensive medical or psychiatric intervention, then valerian can help, particularly in treating stress-related anxiety. Make sure you stick to the recommended dose because valerian can be dangerous if taken to excess.
The four herbal remedies above should between them be all you need to treat your anxiety. One major problem is that, just like any chemical drugs, they only treat the symptoms and not the underlying cause which is something you and your physician will have to work on yourselves.
However, until then, the above herbal remedies for anxiety disorders are generally safer to use than prescription drugs and each has a well proven effect, both on the symptoms of anxiety and on depression.
Use Curamin For Painful inflammation and see how your life can change!
June 15, 2010 05:10 PM
Everyone experiences occasional pain at some time in their lives. We use the word pain in our jargon to describe something unpleasant and to indicate the necessity of toughening up such as “no pain no gain”. As common as the word pain may be, there are many misconceptions about pain. Four out of five Americans believe that occasional pain is just natural and unavoidable due largely to getting older. More than one quarter of Americans believe there is absolutely nothing they can do to relieve their personal pain.
Pain is a warning signal that something has gone wrong in the body or that something is damaged. Pain is so unpleasant that it motivates you to remove yourself from the cause of this damage as quickly and completely as possible.
There are four ways to relieve occasional pain:
1. You can leave the pain alone, but flood the body with feel-good substances that push the pain signals out from your consciousness (drugs).
2. you can put the person asleep and do surgical procedures to cut nerves and stop the pain.
3. You can impact the nervous system the internal wiring that carry the pain signals to dull them so that the signal becomes less distinct and weaker.
4. You can target what is causing the pain in the first place (most recommended). Occasional pain can be perfectly normal for instance, starting a new exercise routine when you are a bit out of shape. When dealing with type of pain, helping the body to balance its inflammation response can have tremendous impact.
This is where curamin is the answer to pain problems. Curamin contains four high potency ingredients that make it work so well. The first ingredient is curcumin from Turmeric. Curcumin is a super antioxidant with a ORAC value of 1592.27 each gram. That’s 24 times stronger than blueberries. Curamin also contains Boswellia, DLPA (DL-phenylalanine) which help fight inflammation and maximize the endorphins and enkiphalins in our own body. It finally contains nattokinase which is a systemic enzyme known to help improve circulation.
They all break down as follows:
DLPA: DL-phenylalanine is an amino acid consisting of equal parts D-phenylalanine and L-Phenylalanine. D- inhibits the breakdown or compounds called enkephalins. Enkephalins are associated with positive mood and have been shown to relieve occasional muscle pain due to exercise or overuse. L- is converted into tyrosine, which in turn is used to produce brain chemicals norepinephrine and Dopamine.
Boswellia: Clinically tested boswellia helps reduce the activity of the inflammatory enzyme, 5-LOX (lipoxygenase). A compound (beta boswellic acid) found in boswellia which interferes with its benefitical activity has been removed, greatly increasing the effectiveness of this extract. Curcumin: Curcumin, a compound found in the spice of turmeric, inhibits multiple inflammation pathways in the body. It is also a potent antioxidant. Some of the benefits associated with curcumin include immune system modulation, protection from oxidative stress, and support the body’s natural anti-inflammatory response. The specialized extract in this formula has the highest absorption of any curcumin extract available for maximum health benefit. (Found in Curamin)
Nattokinase: the enzyme nattokinase helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body.
So if you are suffering from chronic pain, give curamin a try and see how well you can feel. If you are concerned about its effectiveness, have no fear, VitaNet ®, LLC offers a 100% Money back guarantee if the product does not work for you.
Horny Goat Weed
December 06, 2008 10:05 AM
Horny Goat weed, correctly named Epimedium, or Yin Yang Huo in Chinese, is one of over 60 herbaceous plants of the Berberdaceae family. It grows naturally in Southern China, and also in Korea, Southeast Asia and some parts of Europe. Other names given to include Fairy Wings and Bishop's Hat.
Horny goat weed has been viewed as a natural alternative to Viagra, and many species of Epimedium are said to possess aphrodisiac properties, and is said to have got its name from a Chinese goat herder who notice that his goats became more 'frisky' with the lady goats after eating the plant. In fact studies have indicated to increase vitality, particularly the libido and male sexual vitality, although it also possesses some other health benefits in its effect on dementia and osteoporosis.
The term 'horny' is used in the colloquial sense, and has nothing to do with the shape of the plant, the flowers of which are star-shaped. In fact the Chinese name for it means 'licentious goat weed', making the English translation quite clear.
The main ingredient in horney goat weed is icariin, a flavonoid glycoside that acts as a PDE5 inhibitor. Others include the similarly named, but totally different chemical, icaritin, and also many other that will be discussed later. It is icariin on which we shall focus for the time being. Since this is central to its effect on erectile dysfunction, some time will be spent on explaining what PDE5 inhibitors do.
cGMP (Cyclic guanosine monophosphate) is a chemical that relaxes smooth muscle tissue, including the vascular smooth muscles in blood vessels. This can lead to the dilation, or increase in size, of blood vessels and increased blood flow. The corpus cavernosum of the penis is a spongy area that runs the full length of the penis, and contains many blood vessels that can be dilated through the action of cGMP and allow the increased blood flow to create an erection.
PDE5 (phosphodiesterase type 5) is an enzyme that can degrade cGMP and prevent the relaxation of these blood vessels, and so prevent them from dilating. A PDE5 inhibitor, such as icariin, prevents the PDE5 from degrading cGMP, and so allow a normal erection. Sidenafil, commonly known as Viagra, is a similar PDE5 inhibitor and works in the same way as icariin. Hence, the effect of Viagra is not to create an unnatural erection, but in fact to allow the cGMP to do its natural work by preventing the phosphodiesterase from stopping it doing so.
This is just one of the effects of horny goat weed: it is a more natural PDE5 inhibitor than Viagra is. It is also more specific than Sidenfil, and does not interfere with any of the other phosphodiesterases that are essential for other purposes. However, its effects do not stop there, because icariin possesses other properties, and is also only one of the many components of epimedium that can increase vitality.
Among these are a number of flavonoids in addition to icariin, sterols and the isoquinoline alkaloid magnaflorine, that possesses antioxidant properties and reduces LDL cholesterol. The exact mechanism by which horny goat weed works to increase sexual desire is unknown, but it is believed that it inhibits the enzyme acetylcholinetsrase (AChE). Cholinergic synapses are the spaces between brain cells that allow electrical impulses to be transmitted, and are an essential component of neuromuscular system response to stimulation.
AChE can stop these from working properly, and prevent neurotransmitters from effectively allowing sexual arousal. Horny goat weed can inhibit the activity of this enzyme and allow the neurotransmitters such as serotonin, Dopamine and norepinephrine to do their proper job in allowing sexual arousal to occur. This, again, is a natural and not a chemical solution. It has also been found to reduce cortisol levels that cause stress which also reduces sexual desire.
The effect of Epimedium on smooth muscles can also aid those suffering from pulmonary hypertension, in which the small blood vessels in the lungs become too narrow to be effective in allowing the transfer between oxygen and carbon dioxide. PDE5 inhibitors can help these blood vessels to relax and so be more easily dilated in the same way as those in the corpus cavernosum. Once dilated, they are able to carry more blood to and from the lungs and allow the reoxygenation process to continue smoothly.
Research has also discovered the possibility of horny goat weed possessing monoamine-oxidase inhibition properties. Monoamine oxidase enzymes can deaminate hormones such as Dopamine, and can significantly reduce the production of testosterone. The inhibitor prevents this happening, and leads to elevated levels of Dopamine, and also of serotonin and noradrenaline. Dopamine encourages the pituitary gland to release luteinizing hormone that in turn promotes the production of testosterone by the testes.
Another property of horny goat weed is that it can protect against the toxin beta-Amyloid, a protein that damages DNA in the brain, causing the death of brain cells and the accumulation of dead cells in your brain. This in turn leads to dementia and potentially Alzheimer's disease. The use of Horny goat weed is being studied closely in relation to this property. The active ingredient here is icaritin (not to be confused with icariin)
Epimedium also has implications in the treatment of the cartilage and bone damage that occurs with arthritis and osteoporosis. It is possible that this is connected with the antioxidant and anti-inflammatory properties of magnaflorine, and icariin has been found to have bone-healing properties. It is known that damaged cartilage treated with horney goat weed displayed signs of growth and regeneration when compared to a placebo.
However, the most popular use of horny goat weed is in its effect on the libido and erectile dysfunction. The effect on the libido and sexual desire works equally well for men and women, and it is a preferred natural remedy to synthetic equivalents such as Viagra, Levitra and Cialis. The added benefits of the natural product render epimedium the preferred and safest solution for many people.
October 31, 2008 04:28 PM
Contrary to popular belief, Attention deficit and hyper activity (ADHD) doesn’t always go away when children grow up. Many of the children affected by this disorder as children carry it on into adult hood. This complicated disease can cause all sorts of problems mostly lost of work.
One survey studying over seven thousand workers between the ages of eighteen and forty four discovered that three and one half percent of these workers studied had ADHD. The ability to concentrate cost these individuals over twenty days of work. Both women and men experience mood, anxiety and most likely abuse drugs and alcohol. Fortunately there is an alternative, changing ones diet can help.
Dietary changes can help reduce the occurrence of ADHD in both children and adults. Have you ever noticed when you eat a meal high in carbohydrates you become sleepy where a meal higher in protein then carbohydrates does not make you sleepy but increase your mental acuity?
A high protein meal can reduce the amount of tryptophan that crosses the blood brain barrier in turn causes more phenylalanine and tyrosine to enter the brain. These two amino acids boost mental alertness. They are converted into neurotransmitters like norepinephrine, epinephrine, and Dopamine which are adrenaline like neurotransmitters. High carbohydrate meals cause an insulin spike in the blood which causes the body to absorb protein into the muscles and frees up tryptophan.
Tryptophan when not in competition with other amino acids will cross the blood brain barrier which then is converted to serotonin a sleep neurotransmitter. To help over come this, one should eat a meal high in protein at breakfast and moderate protein / carbohydrate meal at lunch, leaving the last big meal of the day rich in carbohydrates.
Some older individuals may notice that they have a hard time sleeping at night; this may largely be due to a high protein meal later in the evening which stimulates the brain. A over stimulated brain will hinder ones sleep and could cause insomnia.
Other things that can help with ADHD are omega-3 fish oil that is high in DHA, phosphatidyl serine, and DMEA. The later two convert to neurotransmitters that can help support healthy mental function and alertness.
B Vitamin Complex
June 23, 2008 03:19 PM
The vitamin B supplement you take is a mixture of nutrients that, although they share the same vitamin letter, are in fact distinctly different chemical entities. The reason that they share the same reference letter of the alphabet is that they are all essential water soluble vitamins (Vitamin C being the only other), they frequently work in synergy with each other and they often come from common sources and have similar properties in the body. They were therefore at one time believed to be just the one chemical entity.
They are essential in that they must form part of our diet because our bodies cannot manufacture these substances from others, and although most share common biochemical and health functions, there is no health function that requires all of them, and none of them can be totally replaced by another.
The B-Vitamin complex that you take can consist of as many as eight different B vitamins, each of which is essential for a healthy body and at one time it was believed that this mixture was only one single vitamin. That is why they are collectively known as vitamin B and were subsequently allocated numbers: it was only later that the individual components were discovered.
These eight are vitamin B-1 (thiamine), vitamin B-2 (riboflavin), vitamin B-3 (niacin), vitamin B-5 (pantothenic acid), vitamin B-6 (pyridoxine), vitamin B-12 (cobalamins), biotin and folic acid (folate). They are found in yeast, liver, tuna, bananas and rice among other sources, and, as with all vitamins, without them life would not be possible. Not all vitamins are found in each of these food sources, and vitamin B-12, for example, is available in nutritional quantities only from animal sources.
Knowing what they are is all very well, but what does your body do with the B vitamin supplement that you take? Before considering that, the reason that a regular supply is important is because of their water solubility. This is a useful property for a vitamin to possess, because it means that they can easily be transported by the body fluids to the tissues where they are needed. The downside, however, is that they are consequently also easily flushed from the body, and your body cannot store any of the B vitamins.
You therefore must have a regular dietary source that can be augmented through supplementation. This is particularly desirable in alcoholics, those on diets to lose weight and vegans who are advised to take a regular vitamin B-12 supplement.
A lack of vitamin B will make you feel tired and lack energy because they play a big part in your body’s metabolism of blood glucose into energy. They also help to maintain a healthy immune system, keep your nervous system in tip-top condition and maintain good healthy skin, hair and muscles. The B complex is also very important in maintaining healthy blood and liver, and each and every component of the mixture has a specific part to play, both on individually and by interaction with others in the B complex.
Rather than examining what your body does with the supplement as a whole, let’s have a look at each component, and what your body does with that. Taking them one at a time, thiamine (B1) helps you to burn carbohydrates to generate energy. It is highly water soluble and must be taken daily. In the form of thiamine pyrophosphate it plays a key part in the metabolism of carbohydrates to energy, and also in the metabolism of certain amino acids. If you rely heavily on a high carbohydrate diet, you will need a good regular supplement of thiamine to be able to convert them to energy.
Vitamin B2 (riboflavin) also plays a part in fat and carbohydrate metabolism and the formation of adenosine triphosphate (ATP), the molecule of energy. It plays a significant part in the health of your skin and a deficiency is associated with mouth ulcers, cracked lips, flaky skin and bloodshot watery eyes. It also activates vitamin B6 and folic acid, one of the cases where the B vitamins work together synergistically.
Vitamin B3, or niacin, is well known to women as a component of some shampoos, and helps to promote health hair. However, this vitamin also takes part in the process of energy creation within your body, and helps to maintain a good muscle tone within the digestive tract. It is also used as a supplement for the treatment of diseases related to high levels of LDL cholesterol and is useful for the treatment of atherosclerosis.
Pantothenic acid is also found as a component of shampoos, so no prizes for guessing one of its functions. Vitamin B-5 plays a significant part in the energy-producing Krebs Cycle, or Citric Acid Cycle, that is used by every cell in your body to generate energy just where it is needed. It is also needed to synthesize acetylcholine, a neurotransmitter needed for good brain function and it helps to reduce stress. Pantothenic acid is also closely involved in the production of cholesterol in your liver: cholesterol is not all bad, and is needed by your body to produce some of the steroid hormones and also vitamin D.
Amino acids are the small units that are used to biosynthesize proteins and ultimately the genes and DNA that determine who you are. The major factor involved in processing these amino acids is Vitamin B6 (pyridoxine), one of the lesser known of the vitamin B complex. It synthesizes and breaks up different amino acids to produce a variety of other compounds, such as the hormones serotonin, melatonin and Dopamine.
Deficiencies in these hormones can be very serious, Parkinson’s disease believed to be connected with a Dopamine deficiency for example, and other disorders include kidney stones, anemia and many skin complaints. Although deficiency of vitamin B6 is rare, it can occur in alcoholics and those with chronic kidney problems. It is believed that many diets are deficient, however, and a good vitamin B supplement would ensure that this did not occur.
Vitamin B-12 is one where deficiency can occur, particularly in alcoholics and vegans. It is available in sufficient quantities only from meat sources, and a supplement is indicated in anyone with a low meat intake in their diet. It is used by your body for the replication of DNA and to allow the normal activity of your body cells. It also helps to control homocysteine levels in conjunction with vitamin B6 and folic acid: homocysteine is a high-risk amino acid associated with atherosclerosis and cardiovascular disease that can lead to Alzheimer’s disease, heart attacks and strokes.
The seventh, biotin (sometimes referred to as vitamin B7) also takes part in the metabolism of energy, but deficiencies have not been known, and the final known member of the B vitamin complex is folic acid. This is essential for cell growth and the synthesis of RNA and DNA in the body. RNA (Ribonucleic acid) is responsible for the synthesis of proteins in your body, and the well known Deoxy-ribonucleic acid (DNA) holds the genetic information of your body. Folic acid is therefore essential in the growing fetus, and any other cellular system that rapidly regenerates such as blood cells and the various cells of the immune system.
Without folic acid your body would be more susceptible to bacterial and viral attack, and less able to protect you from foreign invaders into your body tissues. Although deficiency is not common, folic acid is present in fresh food only and degrades when stored at room temperature and when cooked. A supplement is therefore advisable during pregnancy to help to prevent neural tube defects.
It is evident that the Vitamin B complex plays many parts in the chemistry of your body, and that a supplement can be of benefit in assuring that there are no deficiencies. A good B complex can be found at your local or internet health food store.
June 14, 2008 03:22 PM
DMAE (dimethylaminoethanol) enhances mental function through the improvement of concentration, mental clarity and mental alertness. It is also a mild brain stimulant because it increases and sustains the energy levels in the brain. It also improves the level of restful nighttime sleep because the sleep is deeper and less time is needed to reach a rejuvenated state. DMAE helps to boost mental function through an increase in the levels of acetylcholine and choline. These are the brain’s chemical messengers.
Because of DMAE’s ability to stimulate mental cognitive function, it also has been shown to improve learning, increase intelligence and elevate mood.
* Accelerates mental processes * Decreases irritability and overactivity * Does not cause drowsiness * Improves concentration * Improves IQ * Increases attention * Relieves mild depression * Aids in long-term treatment of schizophrenia
It is believed that DMAE may also increase physical energy. Athletes and other active individuals are using DMAE more and more because of its ability to enhance these brain functions. The connection between the mind and muscles is a means to focus on form and reduce the risk of injury. So, when the mind is enhanced, it communicates better with the muscles to improve and refine function.
Due to DMAE’s mild stimulating effect on the brain, athletes report that it is a good alternative for a quick lift instead of coffee. They also believe the stimulating effects last longer than they do with caffeine. DMAE used as a mild stimulant is also safer and healthier than caffeine.
How It Works:
DMAE, once consumed, is transported to the liver where it is converted into choline through the process of metabolism. A small amount is then converted into acetylcholine, which is a brain transmitter. Through this process, DMAE increases the levels of these brain transmitters (neurotransmitters). This causes a boost in mental cognitive function and memory.
Acetylcholine is also responsible for helping to conduct nerve impulses in the brain. Choline is also converted in the brain into phosphatidylcholine. This chemical rebuilds and protects existing cell membranes inside the brain. DMAE has the ability to cross the blood-brain barrier faster than choline. Through this quicker travel, DMAE enhances cell protection and repair and helps our brains function better and create enhanced, positive behavioral changes in most people.
Other DMAE Uses:
DMAE is being studied for use in aiding a movement disorder in Parkinson’s patients. This disorder, called dyskenesis is caused by L-Dopa, which is administered to treat the effects of the disease. DMAE seems to counteract dyskenesis effectively and safely without interfering with the benefits of the therapy. DMAE is proving to reduce the effects of other disorders that involve involuntary movements. Two of these disorders being treated are blepharospasm (eyelid twitching) and benign essential tremors.
Age spot sufferers may find hope for treatment of their condition as well. DMAE has been found to inhibit the formation of pigment caused by aging (lipofuscin) and liver spots (lentigo). It may actually flush lipofuscin from the body, causing the skin spots to disappear over a few month’s time.
DMAE is being studied for its possible ability in helping to reduce cognitive impairments related to age. Aside from increased mental cognitive function, research has shown that DMAE may also be useful in treating the following conditions.
* Alzheimer’s disease * ADD (attention deficit disorder) * Hyperactivity
The use of DMAE as a regular dietary supplement is increasing steadily. All of its benefits in aiding mental cognitive function and brain stimulation are an attractive quality for everyone. Additional research showing that DMAE is useful in treating debilitating conditions such as Parkinson’s gives us new hope. As research continues and more new uses for DMAE are discovered, its popularity will continue to grow as well.
June 13, 2008 12:18 PM
DL-Phenylalanine has been found to work in conjunction with the body’s natural ability to relieve pain. It helps to lengthen the lifespan of the chemicals in the brain that ease pain. It is especially effective in relieving pain from arthritis and aching muscles.
Some chronic pain can be treated with DL-phenylalanine through the stimulation of nerve pathways in the brain that control pain. Enhanced pain relief has been discovered when D-phenylalanine is used in conjunction with prescribed pain killers. This manufactured form of phenylalanine is used to block an enzyme in the nervous system that increases pain signals. The interruption of pain signals allows the healing mechanisms of the body to begin working faster.
DL-Phenylalanine is a chemical combination of half L-phenylalanine and half D-phenylalanine. L-Phenylalanine is the natural form of phenylalanine found in proteins all over the body. It is found in foods like beef, poultry, pork, fish, eggs, milk, yogurt, cheese, nuts, seeds and certain soy products. D-Phenylalanine is a synthesized form of the chemical, which means it is produced in a laboratory.
Phenylalanine as an Amino Acid:
Amino acids perform various major functions in the body. They assist in fulfilling the body’s basic needs from minerals and vitamins. They can act as neurotransmitters, which carry signals to and from the brain. They also aid in other parts of the body for communication between nerve cells.
Phenylalanine is one of the essential amino acids found in protein. This means it is required for human health, but cannot be manufactured by the human body. Therefore it has to be supplied through food consumption. It can also be found and taken in the form of powder, capsule, tablet or a topical cream. In the body, phenylalanine is converted into tyrosine, which is another amino acid needed to make protein. It is also needed to make certain brain chemicals and thyroid hormones. Phenylalanine deficiency signs include:
A rare disorder called phenylketonuria (PKU) happens in humans who are missing the enzyme required to metabolize phenylalanine. Symptoms of this disorder tend to appear between the ages of 3-6 months. These include:
If PKU is not treated within the first three weeks of life, it can cause severe and irreversible mental retardation. Women who are pregnant or nursing should avoid taking phenylalanine as a supplement in any form. DL-Phenylalanine may cause hyperactivity, jitteriness and anxiety in children.
Phenylalanine is the major ingredient in the artificial sweetener known as aspartame. Products containing this sweetener are required by law to carry warnings on their labels for phenylketonurics. People who have PKU can be severely injured by ingesting the sweetener. Products containing this artificial sweetener include diet sodas, sugarless gums and some sugar substitutes. Some sugar-free versions of Jello, puddings, ice creams, candies and various other items also contain aspartame.
Other Phenylalanine Uses:
Some individuals have reported that taking DL-phenylalanine has improved their mood and aided in treating depression. This is the result of a higher rate of production of the brain chemicals Dopamine and norepinephrine. These chemicals, when out of balance, cause depression, stress and frustration. Elevation of the levels of these chemicals have an anti-depressant effect in the body.
One study suggests that D-phenylalanine has been shown to improve some symptoms associated with Parkinson’s disease. These include: depression, rigidity, walking problems and speech problems.
The combination of L-phenylalanine and UVA radiation may be used to treat the symptoms of vitiligo. This condition involves de-pigmentation (white patches) of skin. The use of L-phenylalanine may help to re-pigment these patches, but further study is necessary.
DL-Phenylalanine has many uses and benefits if taken correctly. As with any new dietary supplement, consult your physician before beginning a new routine.
May 15, 2008 01:21 PM
Copper is an essential trace mineral necessary for life, and it is necessary for the proper function of certain enzymes that allow certain biochemical functions of the body to take place. Without copper neither plant nor animal life would be possible.
Dietary sources include nuts, grains, seeds, beans and other vegetable protein sources. Although it is also obtained from animal sources, these tend to be rich in zinc, and for reasons that will be discussed shortly, the presence of zinc can deplete copper absorption. Other common sources are copper cooking utensils and drinking water from copper pipes. After digestion, copper is absorbed into the body through the stomach and the small intestine. It is also possible for copper to be absorbed through the skin from copper bracelets.
Once absorbed, copper is bound to albumin and taken by the blood to the liver, where it is bound to a plasma protein known as ceruloplasmin. Among the enzymes with which copper is associated as a ‘helper’ are Cytochrome C oxidase, used in the conversion of glucose to energy, Dopamine hydroxylase, an essential component in the biochemical production of adrenaline, and superoxidase dismutase, that protects against the oxidative damage of cell tissue. Of particular benefit are its anti-inflammatory and antioxidant properties, and its role in energy production. Because of its antioxidant effect, copper could well play a very important role in protecting against atherosclerosis, and cardiovascular disease, the ravaging effects of free radicals on body cells and also certain forms of cancer.
Copper is also important in electron transport, and is responsible for the blue coloration of the blood of most molluscs and many arthropods. This is because rather than hemoglobin, these animals use the copper-based hemocyanin for oxygen transport in the blood. Rather than the iron-containing hemoglobin making the blood of these creatures red as it is with mammals, theirs is blue due to the hemocyanin. Copper salts are generally green and blue, as are the blue copper proteins plastocyanin and azurin.
So how is copper used by the body? It is, after all, fairly toxic, as little as 30 grams being fatal to humans, bringing on similar symptoms to those of arsenic poisoning. It is in fact the reason for its toxicity that also renders it so useful to the body. The toxicity is largely due to the ability of copper to accept and donate electrons as it changes between oxidation states. This results in the generation of very reactive radicals that can cause severe oxidative stress. The complete reason for its toxicity has yet to be determined, but the stress caused to body cells by free radical oxidation is a very serious condition.
It is this rapid change in its oxidation state that is valuable to the enzymes with which it is associated. The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase. In doing so the copper is converted to the monovalent state.
It also helps to aid in the production of the strong antioxidant Superoxide dismutase (SOD). What this enzyme does is to catalyze the formation of oxygen and hydrogen peroxide by the dismutation of superoxide, a negative ion consisting of two oxygen atoms and a free electron, and hence a very powerful free radical. Dismutation is the simultaneous oxidation and reduction of the species, rendering the free radical relatively harmless. This type of action on free radicals is a very powerful one, and essential in the body’s fight against such free radical species that are so dangerous to animal cells.
SOD exists in more than one form, and can also contain zinc, manganese and nickel in addition to copper. The internal fluid (cytosol) of practically all eukaryotic cells (cells containing a nucleus) contain a form of Superoxide dismutase dependent on copper and zinc, while most mitochondria contain an SOD with manganese.
Another of the important uses that your body can find for copper lies in the production of hemoglobin. This is because copper is needed for the storage and release of iron to produce hemoglobin, the protein in red blood cells. It is believed that ceruloplasmin is involved in the catalytic formation of ferric iron by the oxidation of ferrous iron, so allowing the iron to be attached to a protein that transfers it round the body to enable its use in the biosynthesis of various ferrous compounds, especially of hemoglobin.
Copper bracelets are commonly worn by arthritis sufferers, and there is a scientific explanation for that. As previously inferred, it is believed to be possible to absorb copper through the skin and copper is known to be involved in the formation of collagen and is a commonly used treatment for arthritis and osteoporosis. Part of its effect on arthritis is likely due to the antioxidant effect of the SOD that helps to reduce the inflammation at arthritis sites.
Although a deficiency in copper can lead to serious health problems, an excess is also harmful. Potential conditions include neurological problems, liver damage and bone abnormalities, although deficiency is far more common because of the competition between copper and zinc. Zinc is a copper antagonist, as is iron and manganese, and copper imbalances can be moderated by the use of these as supplements.
The symptoms of a copper deficiency include fatigue, hair loss, stunted growth, anorexia and a host of other conditions. Luckily, however, a deficiency is rare and most people receive a sufficient amount of copper in their diet. Supplements are available to ensure an adequate intake.
There is still much to be learned about the interaction between copper and enzymes, and there is also a great deal still to be learned of its role in human metabolism and biochemistry than is currently known. However, sufficient is known already for us to be certain that copper is a very important trace element and that we should be certain that our intake is sufficient, given that zinc iron and manganese compete to prevent copper being absorbed by the body.
Omega-3 Fish Oil
May 02, 2008 03:07 PM
The benefits of fish oil come from two long chain polyunsaturated fatty acids: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). DHA primarily helps prevent behavioral and attention issues in children and adults. DHA is good for brain development starting as far back as when we are developing in the womb.
Scientists at Wayne State University in Detroit found that babies who had higher concentrations of DHA in their cord blood had greater visual, cognitive, and motor development when tested at the six month and twelfth month marks. Most pregnant women get less DHA then they need during those last few months of pregnancy. Supplementing with DHA can have profound benefits for baby as well as mother. DHA can extend gestation time which can reduce the rate of premature birthing. Some research suggests that DHA can help fight pre-eclampsia, a life threatening condition that happens to women that are pregnant. Omega-3 fish oil reduces platelet aggregation and vasoconstriction – both of which are symptoms of pre-eclampsia.
Eating fish is a good way to get the needed DHA in our diets but safety is always an issue with the fish that is being consumed. Cold water fish have been known to have potential toxins like mercury, polychlorinated biphenyls, and dioxins. These toxins are not good for developing baby as well as the mother.
Brain power can be boosted in babies who are breast fed because of the high concentrations of DHA present in breast milk. Infants begin developing neuronal pathways associated with learning as soon as they are born and if they are not breast fed they should be supplementing their diet with DHA. Studies suggest that DHA plays a role in the production and regulation of Dopamine and serotonin in the brain. Numerous studies show that breast fed babies have greater cognitive development and visual acuity then those who are formula fed.
The importance of fish oil for infants in brain development is clearly seen, fish oil is also important for older children and adults who want a mental boost. It’s never too late to take fish oil to boost mental health; studies suggest that Alzheimer’s disease can be slowed with the consumption of omega-3 fish oil as well. Have you had your fish oil today?
If burping up fish oil is not your cup of tea, give vectomega a try. vectomega is a dry fish oil that provides the same health benefits you experience with regular oil pills minus the oil.
Addiction Recovery With Chinese Herbs Like Kudzu
November 28, 2007 12:04 PM
Kudzu is Chinese herb that has been identified for the treatment of alcoholism. Anybody who has even had an addiction will tell you that addiction recovery is one of the most difficult of the tasks that life throws at us. Whether it is an addiction to tobacco or to heroin or anything in between is not easy, and those that join the ‘self-afflicted’ lobby do not help, but for the Grace of God...
Alcohol addiction is now potentially the most prevalent addiction in the world. There are now more that drink alcohol than smoke, and alcohol related problems are more than just a social problem, but cause the deaths of over 100,000 annually in the USA. One shudders at the thought of the world-wide death toll. It has been suggested that chemical addictions, as opposed to physical habits, can have chemical cures. Although the jury is still out on this one, there have been some positive results achieved in the treatment of addicts with natural remedies.
One of these natural remedies is the Chinese herb, kudzu. Kudzu is a climbing vine that can grow just about anywhere: in fields, lightly forested land and mountains. It is found throughout China, and also in the south eastern states of the USA. The reason for this strange distribution is that the plant was introduced to the USA by Japan at the 1876 Centennial Expo in Philadelphia.
The large blooms attracted gardeners who propagated them, and when it was discovered that the plant made good forage for animals, Florida nurserymen grew it as animal feed. Its effect in preventing ground erosion rendered it popular during the 1930s and 40s when farmers were paid up to $8 an acre for growing kudzu. Fodder and groundcover were the original uses of this vine in the USA irrespective of its medicinal uses on the other side of the Pacific.
Prior to it being recognized as a useful treatment for alcoholism, the vine had been used in China for generations for the treatment of such conditions as headaches, flu, high blood pressure symptoms, dysentery, muscular aches and pains and the common cold. It is still used to treat digestive complaints and allergies, and find use in modern medicine in the treatment of angina.
It is the root that is mainly used, which at up to six feet tall provides a plentiful supply of its active ingredients. These include isoflavones including daidzein and isoflavone glycosides, mainly puerarin and also daidzin. However, it is in its application in the treatment of alcohol addiction that the root is currently creating interest.
Studies in the 1960s on animals bred with an alcohol craving indicated that daidzein and daidzin reduced their consumption of alcohol when offered it, and further studies have indicated that the mechanism of this was by inhibition of enzymes necessary for metabolizing alcohols. This has not yet been successfully repeated in humans, but the effects on animals cannot be just coincidental. Or can it? That question can only be answered by those for whom kudzu has been found effective, although many laboratory studies have shown that it certainly reduces the alcohol consumption of those with a habitual heavy intake of the substance.
Of all the other substances that have been used in an attempt to reduce the extent of alcoholism in the Western world, none have been found truly effective. The three recognized treatments of Campral (Acamprosate Calcium), approved by the FDA in July, 2004, Naltrexone (Revia) and Antabuse work in three different ways. Campral is useful only once you have stopped drinking and have detoxed, Naltrexone interferes with the pathway in the brain that ‘rewards’ the drinker and Antabuse gives unpleasant side effects that are meant to put the drinker off drinking.
Although all have side effects of one type or another, they have been approved by the FDA, and must therefore be assumed safe if used as recommended. However, none are natural, and kudzu has been found to have no known side effects. It is a type of pea, and did you know that it grows about one foot a day? Luckily it only grows to about 20 feet!
It is kudzu’s lack of side effects that renders it so attractive as a treatment for alcoholism, although more tests are needed before the evidence for its effectiveness can be declared cast iron. Most of the tests to date have been carried out on heavy drinkers rather than true alcoholics, but they have all found the plant effective in reducing the amount that each member of the study drank, even though no limitations were placed on them.
Future studies should probably be designed to determine if the treatment is safe for such groups as pregnant women, young people and those with specific medical complaints such as liver problems. Naltrexone should not be used by anybody with serious liver problems, and even campral is only suitable if you have no more than a moderate liver problem. Since alcoholics can reasonable be expected to also suffer from liver disease, then a treatment that is safe for such people would be very welcome.
A 2002 meeting of the Research Society on Alcoholism in San Francisco named kudzu and St. John’s Wort as being the two most promising treatments for alcoholism. The mention of St. John’s Wort raises an interesting point, and one that must be discussed. That is the question of standardized doses, and what can happen if doses of natural products are not standardized with respect to the identified active constituent.
The reason for the importance of this is that not all sources of a particular herb are equally well endowed with active constituents. Although, for example, a dose of 2.5 grams daily of kudzu root might be recommended, how does the percent content of isoflavones in different roots vary. That variation will mean that the amount of active ingredient taken in one 2.5g dose will differ from that in another, unless there is standardization.
The reason St. John’s Wort brought this to mind is that with this herb, used for some psychological problems such as depression, the active ingredient content was standardized. It was standardized to 0.3% hypericin, a napthodianthrone that causes an increase in Dopamine levels. However, standard doses of St. John’s Wort gave inconsistent results and the reason for this could not be identified. It now has been. The active ingredient is now known to be not hypericin, but hypeforin, what is known as a prenylated phloroglucinol. The herb is now standardized on this substance.
This is a demonstration of the importance of identifying the active ingredients in a herbal treatment accurately, and also of standardizing doses. Kudzu doses must be standardized if their effect is to be consistent. There is now little doubt that addiction recovery is possible with Chinese herbs like kudzu, and who knows what else the ancient civilizations such as the Chinese have to offer us.
Chronic Illness and eating healthy
November 09, 2007 12:43 PM
Chronic illness which exhibits itself as a recurring disease, with lingering and lasting symptoms is a growing pandemic amongst people today. The question is how much of this is due to neglect on the basics of healthy living? Today’s fast paced life style could be a factor for these reoccurring problems. For example, we pride ourselves on keeping five things in the air at the same time; this has caused us to slip from eating three healthy meals per day to drinking a slim fast or popping a diet pill to keep going. Moving away from proper diet and nutrition may be the reason our bodies are breaking down today resulting in chronic illnesses.
Whether you are free from or burdened by illness it is time to take charge of your health! The first thing one can do is basic research. Studies on dietary supplements in scientific and medical research are an ongoing process both in the United States and internationally. If you are interested in finding citations on a particular chronic illness or research that is available I recommend looking at government agencies such as (i) The Office of Dietary Supplements, (ii) The National Institutes of Health (NIH), (iii) The National Agricultural Library (NAL), and (iv) United States Department of agriculture (USDA). It is also possible to obtain research abstracts from different major databases such as MEDLINE for biomedical related articles and AGRICOLA for botanical and agricultural science. To find these different databases and governmental agencies, search google using the respective agency/database name.
Research shows that stress reduction can help to improve energy levels, improve sleep quality, and reduce high blood pressure. The following are some suggestions for reducing stress:
1. Weight lifting is not just about barbells and muscle-building but about stressing the body as a means for relieving stress.
2. Cardiovascular exercises such as jogging and bicycling.
3. Exercise is helpful by increasing blood flow to the brain, release of hormones, stimulates the nervous system and produces a feeling of well being.
Eating healthy including supplementation
1. Vitamin C or ascorbic acid has the ability to boost the immune system. Vitamin C also helps to produce neurotransmitters by converting L-Tyrosine into Dopamine. Along with Dopamine, ascorbic acid also synthesizes norepinephrine and serotonin which have been found to be directly related to control anxiety and depression.
2. B-Vitamins are also the important for reducing stress. For example, Niacin (Vitamin B3) helps the body fight stress in three ways, (i) controls blood sugars, (ii) improves blood flow and (iii) regulates the release of energy from carbohydrates.
Stress is a state of bodily or mental tension resulting from factors which are an unavoidable effect of living. Stress has been linked to coronary heart disease, psychosomatic disorders and various other mental and physical problems. Reducing stress is essential and can be done through diet and exercise. Nutritional science studies the relationship between diet and states of health and disease. Nutritional science has found human nutrition is very complex and varies widely and proper nutrition cannot be obtained by simply eating three meals a day because quite simply the average person just does not eat well. If you eat less than five servings of fruits and vegetables daily it is impossible to obtain all of the vitamins and minerals your body needs. In order to seek assurance that you are getting all your body needs I suggest you take a good multiple vitamins which supplies at least 100 percent of the daily value for various vitamins and minerals. It is a good idea however to discuss with your doctor the best choices as he or she knows your history and specific health needs best.
Supplements good for reducing stress and boosting energy!
March 26, 2007 02:05 PM
More and more Americans are feeling overworked, overtired, and overcome by life’s demands. We just do not have the energy we need to meet our responsibilities to the people we care about. More importantly, we don’t even have the energy to have fun! It seems that a constant feeling of fatigue has become part of the American way of life.
Research has shown that the same processes that cause lack of energy can rob us of sleep, saddle us with excess weight, disrupt our hormonal balance, and create significant amounts of stress in our daily lives. Chronic stress can dramatically contribute to fatigue, sleep disorders, irritability, and anxiety. The research simply confirms what most of us already know – uncomfortable stress can really wear us out mentally and physically! It can take away the satisfaction of a job well done. It can take away our ability to believe in ourselves. And, sadly and maybe most importantly, continual stress can take the fun and joy out of life.
In a separate issue of Ask the Doctor, we discuss the energy and sleeping needs of people suffering from chronic fatigue syndrome and fibromyalgia. In this issue, I discuss the 3-step process I call “Vitality 101.” People do not have to accept pain, insomnia, or fatigue. It’s time for everyone to feel great and have a life they love!
Step 1 – Nutrition
Good overall nutrition is important for everyone! As a foundation product to support energy levels, a powdered drink mix is a pleasant, easy way to ensure that you are taking all of the necessary vitamins, minerals, and amino acids that you need to have great energy all through your day.
The following chart lists the most critical ingredients. You can see that almost all of the vitamins and minerals work together to help improve energy levels and overall health.
In addition to the powdered energy drink mix, it is important that you also take a high potency vitamin B-complex supplement. This should include niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, which are especially important to restore the energy production needs of your body. It is also critical to get enough water, as most Americans are chronically dehydrated.
Step 2 – Rest Your Body
Having trouble sleeping is one of the most troubling symptoms of stress. While the stress is wearing us down and making us tired, it’s also keeping us tense and unable tot relax. The result? That easy drift into sleep becomes harder and harder. And if we are lucky enough to actually get some shut-eye, stress will often wake us up, sometimes several times a night.
This occurs because excess stress suppresses the sleep center in the brain. It is important to break the “stress/insomnia cycle” early, before it results in pain and hormonal and immune dysfunction!
Because good quality sleep is how the body repairs and re-energizes itself, it may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Look for a supplement that has a blend of herbs that promote deep sleep, such as valerian, L-theanine, hops, passionflower,
Step 3 – Manage Excess Stress Levels
In this fast paced world, it is important to learn to manage the stressor in our lives. Glandular extracts, such as raw adrenal extract, can offer natural support to help our bodies deal with the effects of stress and, in turn, can boost your energy levels. Exercise is another stress buster. Using your body physically is important for good health. Find something that is fun for you, however, or you are unlikely to stick with it!
Q. Does stress zap my energy in any other ways besides making me lay awake at night and causing me to be a zombie the next morning?
A. Most people are familiar with the body’s dramatic response to an emergency. The heart pounds, the muscles constrict, and the lungs expand – and while this is happening, we are capable of greater than normal strength and speed. This response is the body’s way of rescuing itself when faced with an emergency. We don’t have to think about it to make it happen. It’s automatic.
The same can be said of a chronic stress response. Whether we’re late for a business meeting because we’re stuck in traffic, or worrying about how we are going to pay for our children’s college tuition, our response to stress happens automatically. The difference between the two is that the body’s response in an emergency starts and resolves itself quickly. The response to being stuck in traffic may not.
The body makes the “stress hormone”, cortisol, to handle the normal stresses of day-to-day living. But in an emergency situation, the adrenal glands, located above the kidneys, secrete increased amounts of this hormone until the emergency passes. Then the body returns to its normal function. Unfortunately, however, chronic stress is more complex. When our body is subjected to increased amounts of the hormone, cortisol, for an extended time, it can lead to a condition known as “adrenal burnout” or “adrenal fatigue.” While it’s true that very large amounts of cortisol can have damaging effects on our hormones, too little cortisol doesn’t allow us to respond to stress properly. It’s really a matter of balance.
Q. How can I control the stress in my life and re-energize?
A. Many people who are under constant stress may have adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.
The good news is that changes in our hormone levels can return to normal when stress is decreased. The key in learning how to deal with daily stress is to allow the body to return to its normal state. I discuss additional techniques for coping with stress in my recent book Three Steps to Happiness! Healing Through Joy (see my website, www. jacobeitelbaum .com, for more information). In addition to stress control, it is important to supplement your adrenals with a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy, which uses the concentrated forms of bovine (cow) or porcine (pig) glands, can improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacked and thus repaired the malfunctioning gland.
If you are one of the unlucky folks with stressed-out adrenal glands, you should see great results from taking raw adrenal supplements. Be sure to buy adrenal extract supplement that contains both whole adrenal and cortex adrenal.
The best adrenal supplement should also contain vitamin C, vitamin B6, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.
Did your grandmother ever tell you to eat your liver so that you didn’t get “tired blood?” Well, it turns out that she was right. Liver extract is another glandular extract that can help improve energy levels.
Liver extract is an excellent source of highly bioavailable nutrients including iron, B vitamins (especially B12), and other minerals. The stamina and energy-enhancing benefits of liver are widely touted. Liver extract has been shown to support healthy function of the liver and increase the energy levels inside our body.
Because heat will destroy the key components in the liver, a high quality liver extract supplement should be cold-processed and encapsulated to enhance speed and absorption of nutrients from liver. A high quality aqueous liver extract supplement should also contain vitamin B12 to support healthy blood iron and oxygen levels to energize.
Q. It will be great to get a good night’s sleep. Are there also any other natural alternatives that could help promote relaxation and increase my energy levels during the day?
A. Yes, there are. Rhodiola rosea is an all-natural herb that has long been used to help relieve stress and increase energy. Rhodiola has also been used to lift our moods, improve sexual satisfaction, and even help in certain nervous system disorders. First used in Siberia and
In clinical trials, the most effective Rhodiola rosea extract was found to contain 3% rosavins and 1% salidroside. While there are many Rhodiola supplements in health food stores, only those containing these specific amounts can provide the best results.
Altered digestion, food intolerances, decreased energy, fatigue, cognitive problems, and sleeplessness create the need for changes in daily living routines. These can include alterations in diet; exercise modifications; alterations in activities of daily living according to one’s energy level; and sleep/rest management. All may require the assistance of a professional clinician, such as a chiropractor, nutrition specialist, physical and/or occupational therapist, mental health professional, or sleep therapist.
Super busy lives demand super strength nutrition. Begin each day with a powdered nutritional supplement after getting at least 8 hours of sleep each night. In addition to the nutritional beverage mix, a vitamin B complex supplement should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients to combat your fatigue. Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Rhodiola rosea, and ginseng can offer additional natural nutritional support in your busy life to boost your energy levels. These nutritional supplements can be used daily and you will feel energized to get through each day’s challenges and opportunities!
Neurological Health and CoQ10
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.
Q. Isn’t CoQ10 a supplement for heart health?
A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.
Q. How does CoQ10 affect brain health?
A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.
The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.
The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.
Q. What is the blood-brain barrier and why is it important?
A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.
Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.
Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.
Q. If CoQ10 is made in the body, why take supplements?
A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.
Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.
Q. How does CoQ10 help people with Parkinson’s disease?
A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical Dopamine. Stored and newly synthesized Dopamine is depleted. The Dopamine depletion causes nerve cell degeneration.
A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.
Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.
The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.
The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.
Q. What were the results of clinical research on Huntington’s Disease?
A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.
Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.
Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.
Q. What other diseases could benefit from CoQ10 supplementation?
A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.
In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.
ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.
Q. Can taking CoQ10 prevent neurodegenerative disease?
A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.
Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.
Q. How much CoQ10 should I take?
A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.
CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What should I look for in a CoQ10 supplement?
A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.
CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.
All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
January 05, 2006 10:29 AM
Fact: Millions of Americans trying to lose weight are horrified to see their bathroom scales inching uncontrollably upwards.
And these numbers increase every single year. Making matters worse, many of these same people are shocked to find their energy levels slipping inexorably downwards. I guess I’ve just got a slow metabolism…” “You can’t get as much done when you start getting older…” “Why am I always so cold?” Sound a little too familiar? What if there was a safe and natural way to energize your metabolism and keep it operating at its youthful, maximum efficiency? While it is true that metabolism slows somewhat with age, its not inevitable that every one of us is destined to end up with more weight to move around and less energy to get there. There are people in their 30’s, 40’s, 50’s, 60’s and beyond with all the vibrant energy they need. There are people who end every day with a list of important accomplishments completed. So what’s their secret? It may well be a healthy, fully functioning thyroid.The human thyroid is a butterfly-shaped gland located in the front of the neck that wraps around the trachea. It has but one job - to produce the two critical thyroid hormones we need to keep our metabolism efficient. In fact, these hormones are indispensable for our bodies to convert calories into energy – and that’s the crux of metabolism. These two hormones, triiodothyronine and thyroxine, or T3 and T4 respectively, are produced in the thyroid when the iodine in our system teams up with the amino acid L-tyrosine. Sounds simple, right?
Think again. Human metabolism is a highly intricate process that can be adversely affected by a wealth of variables. One important variable that we can control, is the nutrient mix our thyroid keeps on hand to operate. In order for metabolism to occur with any respectable level of effectiveness, the body must have a full supply of thyroid supporting nutrients on hand at all times. If you aren’t willing to deliver the nutrients it needs to function properly, chances are, it won’t be able to do what it’s supposed to (which is to keep your metabolism fired up and your energy resources fully charged).Don’t despair. There is good news. Encouraging and maintaining healthy thyroid function may be easier than you might imagine. This master gland of metabolism is often very responsive to the right combination of thyroid supporting nutrients.
Yes, a healthy diet will promote a healthy thyroid, but some of the nutrients that are especially helpful in supporting healthy thyroid function are not likely to be found in your local market. That is, unless you happen to be shopping in India or Ireland. So just what are the critical nutrients for a healthy, energized thyroid? L-Tyrosine. This amino acid plays an essential role in the production of thyroid hormones, in addition to hormones that affect mood including epinephrine, norepinephrine, serotonin, and Dopamine. And while our body can naturally produce some Tyrosine from other amino acids, as we age, our bodies may not be able to keep up with the needs of a demanding thyroid. During metabolism, tyrosine joins forces with iodine in order to produce the thyroid hormones needed to efficiently convert (metabolize) the calories from our diet into expendable energy. A weak reserve of tyrosine can leave us feeling sluggish. As a result, our body reacts by storing more calories as fat for energy.
Iodine. Another key player in the metabolism game. Without it, metabolism simply can not take place. The thyroid is the only gland in the human body capable of absorbing this trace element. Typically found in shellfish and iodized salts, iodine is stored in the thyroid gland until needed for the production of the thyroid hormones triiodothyronine and thyroxine. When combined with L-tyrosine and other nutrients these two work synergistically to produce T3 and T4 thyroid hormone. Moreover, iodine deficiencies have been linked to the formation of goiters, decreased energy and lack of concentration.
Irish Moss. A natural vegetarian source of many thyroid-supporting nutrients, including Iodine, a key component in healthy metabolism. Irish moss has been consumed for thousands of years, and many herbalists encourage its use to contribute to sound glandular health.
Selenium. This naturally occuring trace mineral is well known for its strong antioxidant properties and natural synergism with other vitamins. Supplementing with selenium is essential for anyone concerned with sluggish thyroid performance.
Guggul. Technically known as Guggulsterone, the Gug¬gul tree is native to India, and emits a resinous sap that has been used for centuries as part of India’s traditional medicine known as Ayurveda. Studies have shown that the purified plant sterol extract from Guggulsterone can promote healthy thyroid function, and assist the body in maintaining normal production of thyroxine and triiodo¬thyronine.
Simply put, the thyroid gland relies heavily on a host supporting nutrients to produce the hormones needed to ensure that metabolism goes off without a hitch. Without these vital nutrients, our ability to metabolize food may slow down. Here’s an easy way to remember how this process works. The less thyroid supporting nutrients we have, the less thyroid hormone (T3 and T4) we produce.
The less thyroid hormone we produce, the less efficient our metabolic process becomes. The less effective our metabolic process becomes, the less energy we produce. The less energy we produce, the more prone we are to weight gain and fatigue.
NOW® Thyroid Energy was scientifically formulated to help maintain healthy thyroid function by incorporating a powerful blend of thyroid sup¬porting nutrients. With a full gram of L-Tyrosine (the direct precursor to thyroid hormone production) in addition to Iodine from Kelp, Selenium, Guggul, Zinc, Copper and a perfectly balanced blend of B vitamins, NOW® Thyroid energy just may be the boost you’ve been looking for.
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood
As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body.
There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable.
Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel.
SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.*
SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, Dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance.
As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants.
Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health.
SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification.
SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a stabilized form.
SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability.
This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed