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Caprylic Acid - What is it and what are its benefits? Darrell Miller 9/24/22
CBD comes from Cannabis Sativa Darrell Miller 10/9/20
Study: Taking protein supplements before going to the gym can leadto improved post-workout burn Darrell Miller 5/3/19
Protein Powder: 7 Best Types + How to Use VitaNet, LLC Staff 9/19/18
Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries Darrell Miller 6/8/18
World's Largest CBD Extraction Plant to be Built in Western Ky. Darrell Miller 12/26/17
A New Marijuana To Relieve Pain Without The High Darrell Miller 1/19/17
What are the Health Benefits of Beta-Glucans Darrell Miller 12/22/14
EGCG in green tea Darrell Miller 5/10/14
Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes? Darrell Miller 5/7/14
Facts about whey protein. Darrell Miller 1/24/14
How cat's claw as a natural immune system booster to treat and prevent diseases Darrell Miller 11/1/13
What Are The Health Benefits Of Inositol Crystals? Darrell Miller 12/28/12
The Tremendous Health Benefits Of Omega- 3 Fatty Acids Darrell Miller 11/10/12
Lecithin And Its Brain Boosting Properties Darrell Miller 3/2/12
Melatonin, Sleep, and insomnia Darrell Miller 2/8/12
How Does Serrapeptidase Support A Healthy Immune System, Regulate Inflammation, And More? Darrell Miller 9/1/11
How Does Malic Acid Help With Fibromyalgia? Darrell Miller 8/22/11
How Does Grapefruit Seed Extract Help Fight Candida Yeast Infections? Darrell Miller 8/8/11
What is Red Marine Algae And What Are Its Health Benefits? Darrell Miller 6/1/11
Agave Nectar Darrell Miller 4/8/10
Pine Bark Extract Darrell Miller 10/7/09
Ginseng, Its Good For The Body Darrell Miller 10/5/09
Detoxify With L-Citrulline Darrell Miller 4/13/09
Hoodia Gordonii Darrell Miller 12/10/08
NOW® Introduces Genuine Whole Food™ Labeling Darrell Miller 9/27/08
Hoodia Extract And Appetite Darrell Miller 9/26/08
Panax Ginseng Darrell Miller 9/22/08
Antioxidants Darrell Miller 8/14/08
Vitamin C Darrell Miller 8/12/08
Cat's Claw Darrell Miller 8/6/08
Butcher's Broom Extract Darrell Miller 5/2/08
L-Carnitine For Health And Wellness Darrell Miller 4/16/08
Third- The Science (Putting It All Together) Boswellia & Inflammation Darrell Miller 4/3/08
Urinary Incontinence and Overactive Bladder: The Silent Conditions Darrell Miller 2/7/08
OptiMSM Darrell Miller 6/26/07
Scientific Method of Evaluating the Effectiveness of Natural Medicines Darrell Miller 4/21/07
EpiCore Benefits Darrell Miller 4/9/07
N-acetylneuraminic acid Darrell Miller 3/8/07
Olive, With a Twist – The Leaves of the Olive Tree are as beneficial to our health as the Darrell Miller 10/7/06
The True Whey, boost your immune system Darrell Miller 4/29/06
Perplexed about Protein? immunoglobulins to boost the immune system. Darrell Miller 4/29/06
Fighting fat with fat makes sense with conjugated linoleic acid. Darrell Miller 4/3/06
TriOxil the solution for your acne! Darrell Miller 2/25/06
New Frontiers in Enzyme Supplementation Darrell Miller 2/16/06
Benefits of L-Carnitine Darrell Miller 2/12/06
Benefits of Acetyl-L-Carnitine Darrell Miller 2/12/06
Scientific References Darrell Miller 2/11/06
Essential Oil FAQ's - What are essential oils? Darrell Miller 1/13/06
Gr-8 Dophilus Darrell Miller 12/29/05
Vitamin C FAQ's Darrell Miller 12/27/05
Glucosamine & Chondroitin - JOINT HEALTH Darrell Miller 12/22/05
SAMe (S-Adenosylmethionine) Darrell Miller 12/17/05
Nattokinase Fact Sheet Darrell Miller 12/8/05
CLA Extreme Fact Sheet Darrell Miller 12/7/05
GliSODin® (The Antioxidant Catalyst) 100 mg Fact Sheet Darrell Miller 12/7/05
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Darrell Miller 12/7/05
Rhodiola - Adaptogenic Herbs & Immunity Enhancers Darrell Miller 12/6/05
Weight Loss and Toxicity: The Missing Link Darrell Miller 11/22/05
Chloride: The Forgotten Essential Mineral Darrell Miller 11/20/05
Ideal Vision from Thompson Nutritional Darrell Miller 11/18/05
Adverse Reactions to Foods and Dietary Supplements Darrell Miller 8/27/05
Omega Man - For Men Interested in Optimal Health Darrell Miller 8/12/05
Nattokinase - Systemic Enzyme for Healthy Circulation Darrell Miller 8/3/05
Celadrin - Benefits Darrell Miller 7/27/05
Cancer fighter found in broccoli Darrell Miller 7/27/05
WILD YAM: NATURE’S ANSWER TO HORMONAL IMBALANCES Darrell Miller 7/25/05
FORMS OF STEVIA Darrell Miller 7/15/05
WOUNDS AND ST. JOHN'S WORT Darrell Miller 7/15/05
ST. JOHN’S WORT AND AIDS/HIV Darrell Miller 7/15/05
HYPERICIN Darrell Miller 7/14/05
THE ORIGINS OF PYCNOGENOL Darrell Miller 7/13/05
HAWAIIAN NONI (Morinda citrifolia) Darrell Miller 7/11/05
Cinnamon may control sugar levels... Darrell Miller 7/8/05
Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story Darrell Miller 6/29/05
CHITOSAN: The Fiber that Binds Fat Darrell Miller 6/25/05
CHEMICAL COMPOSITION AND NUTRITIONAL VALUE Darrell Miller 6/25/05
Cultivation and Export Darrell Miller 6/25/05
HISTORY Darrell Miller 6/25/05
YEAST INFECTIONS AND GARLIC Darrell Miller 6/25/05




Caprylic Acid - What is it and what are its benefits?
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Date: September 24, 2022 10:55 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Caprylic Acid - What is it and what are its benefits?

NOW® Caprylic Acid is a naturally derived nutrient also known as octanoic acid. Caprylic acid is a medium-chain fatty acid (MCT) that is naturally found in coconut and palm kernel oil. Caprylic acid feeds friendly bacteria and fights candida. Candida overgrowth can lead to feelings of fatigue, moodiness, headaches, and digestive issues. Taking caprylic acid can help restore balance in the gut and improve overall health.

What is Caprylic Acid?

Caprylic acid is a type of saturated fatty acid that has antimicrobial properties. It occurs naturally in coconut oil, palm kernel oil, and human breast milk. Caprylic acid is also known as octanoic acid. It gets its name from the Latin word for “egg” because caprylic acid was first isolated from egg white in 1807.

Benefits of Caprylic Acid

Caprylic acid has many potential health benefits. It has been shown to fight candida, which is a type of yeast that can overgrow in the body and lead to fatigue, moodiness, headaches, and digestive issues. Caprylic acid also helps to restore balance in the gut microbiome by killing bad bacteria and promoting the growth of good bacteria. Additionally, caprylic acid has anti-inflammatory properties and can help to improve cognitive function and joint health.

How to Take Caprylic Acid

Caprylic acid is available in SoftGel form. It can also be taken as an oil or added to food or beverages. The recommended dosage depends on the form you are taking as well as your age, health, and other factors.

In Summary:

NOW® Caprylic Acid is a naturally derived nutrient with many potential health benefits. It can help fight candida, restore balance in the gut microbiome, improve cognitive function, and reduce inflammation. Caprylic acid is available in SoftGel form. If you're struggling with Candida or other bacterial overgrowth in the intestinal tract, consider using caprylic acid and take back control of your life.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6463)


CBD comes from Cannabis Sativa
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Date: October 09, 2020 10:17 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD comes from Cannabis Sativa


Cannabis Sativa is an herb that has been well documented (used) in history for thousands of years. it is extremely unique in the fact that it contains the perfect profile of phytocannabinoids. In order to get the full benefits of cannabinoids, a perfect plant is needed.

When looking for quality CBD, one must stick with known name brands like CV Science (PlusCBD), Hempceutix by Natures Plus, Leaf Therapeutics by Solaray, and Smart Organics.

Unfortunately, it can be confusing choosing a CBD product because at the moment there are more than 400 brands of CBD.

Inferior quality hemp products may:

  • Use poorly grown or inactive hemp, with little or no cannabinoids.
  • Use harmful solvents and other harmful extraction methods.
  • Use isolated, individual cannabinoid compounds.
  • Use synthetic cannabinoids, which are actually dangerous and can cause injury.
  • Be Difficult to absorb.
  • May not contain the potency they claim.

Sticking with name brands that are known to be effective and hold to supplement industry standards are important, the above mentioned brands use CO2 extraction to preserve all the active ingredients found in the Cannabis Sativa plant. Consuming a full spectrum CBD is important!

A Quality Hemp derived CBD can help improve ECS Function:

  • Improve the natural release of cannabinoids each cell makes in the body.
  • Can Directly adhere to the endocannabinoid receptors in our body's.
  • Increase the amount of available cannabinoids in the body.
  • Promote or increase endocannabinoid receptor sensitivity and function in the body.

Researchers have discovered 180 different cannabinoids found naturally in hemp, each are able to work in a different way in the body. Only a select few brands provide the full spectrum cannabinoids we need for better health.

If you are looking to ease pain, reduce anxiety, improve sleep, and balance the body, consider using a full spectrum, Name Brand CBD product and feel the difference it can make in your life!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6367)


Study: Taking protein supplements before going to the gym can leadto improved post-workout burn
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Date: May 03, 2019 04:08 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study: Taking protein supplements before going to the gym can leadto improved post-workout burn





Recent research published in the Journal of the International Society of Sports Nutrition indicates that taking your protein supplement before working out can help increase your body’s fat oxidation. In a study of 11 college-aged males who took either whey or casein protein supplements prior to moderate exercise, it was found that both post-exercise fat oxidation and post-exercise energy consumption improved. Casein has more of an impact in this study than whey. This strongly suggests you should take your protein supplement before exercising.

Key Takeaways:

  • It has been shown that the timing of when proteins are taken really matters as researchers have realized that taking protein supplements before workout improves post-workout burn.
  • 11 healthy, recreationally active college males were recruited for the study and they did not take any caffeine 30 days before the study.
  • The proteins that the participants took were 25 g of whey protein isolate, 35 g of casein protein, and 25 g of food additive maltodextrin.

"Published in the Journal of the International Society of Sports Nutrition, the study looked at the effect of taking protein supplements before exercise on fat oxidation and energy expenditure during and after a bout of moderate-intensity exercise. Previous research has shown that pre-exercise protein consumption may promote fat oxidation, at the same time, minimize protein degradation during exercise."

Read more: https://www.naturalnews.com/2019-03-26-protein-supplements-before-gym-improve-post-workout-burn.html

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Protein Powder: 7 Best Types + How to Use
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Date: September 19, 2018 04:42 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Protein Powder: 7 Best Types + How to Use





Protein Powder: 7 Best Types + How to Use

Protein powder is commonly used amongst body builders, athletes, and every day people working out. Recent research has shown that it could improve your skin health and even improve you immunity. Protein powder is made from animal and plant-based sources. The common forms of protein powder include; hemp, egg, pea, rice, bone broth, soy, whey and more. There are three common forms of protein powder called concentrates, isolates, and hydrolysates. Protein powdering containing bone broth is one of the best kinds.

Key Takeaways:

  • Once the go-to secret of body-builders, protein powder is beginning to gain popular interest as a supplement to increase lean muscle mass and overall health.
  • Many protein powders incorporate vitamins, minerals and fiber, making them an excellent ally in the fight to lower cholesterol levels.
  • The primary protein source for powders can vary greatly, but some variants include, egg, hemp, soy, rice whey and pea.

"Produced from both plant-based and animal sources, there are many types of protein powders available to tailor to any diet plan, taste palate or personal preference."

Read more: https://draxe.com/protein-powder-best-types/

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Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries
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Date: June 08, 2018 09:16 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries





Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries

Parasites are a more common problem in some parts of the world, where soil quality is particularly conducive to their survival and growth. Unfortunately, for individuals that get infected with these parasites, it's becoming harder to get rid of them, as successive strains become more resistant to drugs.

Fortunately, new research is discovering that keeping parasites at bay and destroying those already present may have more to do with the environment of the gut. Individuals from villages in Indonesia and Liberia were the data pool used to find guts harboring parasites as well as those free of them. It was found that some bacteria were actually assistive of the parasites, while others made it hard on them. Since inflammation is the way that the gut generally fights off parasitic invasion, those bacteria that are anti-inflammatory are not useful in ridding the body, although those that aid in producing an inhospitable environment are. It may be that a eating a great deal more fermented foods could be a key, as such foods encourage the production of friendly and useful bacteria.

Key Takeaways:

  • Researchers used a data pool culled from fecal samples of Liberian and Indonesian villagers to try and discover what sort of gut environment is hospitable or hostile to parasitic invaders.
  • Despite the distance between the village sources, the gut environments were very similar and scientists were able to isolate many microbes.
  • The lower incidence of parasites in some individuals was deemed as possibly related to inflammation, which is the body's way of ousting parasites.

"Your ability to fight off parasitic worms may be aided by your gut microbiota."

Read more: https://www.naturalnews.com/2018-06-05-gut-microbes-can-fight-parasites-probiotics-may-reduce-infections-and-severity-of-infections-in-developing-countries.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5630)


World's Largest CBD Extraction Plant to be Built in Western Ky.
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Date: December 26, 2017 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: World's Largest CBD Extraction Plant to be Built in Western Ky.





A company, called Kings Royal Biotech has decided to partner up with a Chinese industrial hemp development company, in order to open the largest cannabidiol (CBD) processing plant in the United States. CBD is a substance that is extracted from the hemp plant, but it is not psychoactive. In fact, CBD has been shown to be useful in treating a variety of medical conditions, including epilepsy and chronic pain. THC, on the other hand, is the substance in marijuana that can give a user a psychoactive effect. King Royal intends to grow hemp that is free of THC, so that the CBD could be isolated and utilized for medicinal purposes, without the risk of giving the user a psychoactive effect. Additionally, this means that the products are completely legal, in accordance with the laws of the federal government of the United States.

Key Takeaways:

  • This plant being built in Kentucky will be they largest in the country to produce CBD
  • It is a partnership with a Chinese company that is the only current manufacturer of this pure product.
  • It is the first approved in the US to make this product with hemp instead of cannabis.

"Under Federal Law industrial hemp cannot contain more than .3 percent THC, so there is no chance of any users having an altered state of mind from this product."

Read more: http://surfky.com/index.php/muhlenberg/news-muhlenberg/179-news/kentucky/125400-world-s-largest-cbd-extraction-plant-to-be-built-in-western-ky

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A New Marijuana To Relieve Pain Without The High
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Date: January 19, 2017 02:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A New Marijuana To Relieve Pain Without The High





The pure medical value of marijuana is apparently being isolated without getting the user high, LatinosHealth reports. The two main molecules in marijuana are THC (which contains the "high"), and CBD, which does not get the user high, but can relieve pain. Efforts are being made to isolate the CBD side of marijuana for pure medical use.

Key Takeaways:

  • The medicinal value of the intoxicating plant Marijuana has often been contested because of its side effects but a recent study claims it can be successfully used as a pain reliever and that too without getting high!
  • According to the Washington Post marijuana consists of two main molecules, one is an intoxicating agent called tetrahydrocannabinol or THC a mind altering substance and the other cannabidiol or CBD which does not get the user high.
  • Another New York University neurologist Orrin Devinsky and his colleague Daniel Friedman observed that patients receiving CBD apart from their usual medicines had 39 percent lesser convulsive seizures than others.

"Earlier researchers were of the opinion that CBD had no use in the human body while THC was used to treat pain, nausea, loss of appetite and other problems but that notion has changed as CBD has been used in the treatment of diseases like epilepsy, anxiety, schizophrenia, heart disease and cancer."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.latinoshealth.com/articles/22451/20170106/new-marijuana-relieve-pain-without-high.htm&ct=ga&cd=CAIyGjViYjkzZDJlODZhNjI0ZWE6Y29tOmVuOlVT&usg=AFQjCNF3P1maud1n4GwSlTDPPTgnFqgDXQ

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What are the Health Benefits of Beta-Glucans
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Date: December 22, 2014 04:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are the Health Benefits of Beta-Glucans

mushroom beta-glucan

What are Beta-glucans?

Beta glucan is a biological response modifier that nutritionally activates the immune response through the Dendritic, Macrophage and other immune cells to produce various therapeutic effects.

Beta-glucans are sugars found in the cell walls of algae, fungi, lichens, bacteria, yeasts, and plants, such as oats and barley. They can be use as medicine.

Benefits of beta-glucan

Beta-glucans are use for cancer, diabetes, HIV/AIDS and high cholesterol. Beta-glucans are also use for boosting the immune system in people whose body defenses have been weakens by emotional or physical stress, chronic fatigue syndrome or by treatments such as chemotherapy or radiation. Beta-glucans are also used for ulcerative colitis, hepatitis, multiple sclerosis, aging, H1N1 flu, Lyme disease, allergies, fibromyalgia, ear infections, rheumatoid, asthma and crohn's disease.

Beta-glucans is applied to the skin for wrinkles, dermatitis, burns, eczema, bedsores, radiation burns, wounds and diabetic ulcers.

Beta-glucans can be given by injection into the muscle or intravenously to boost the immune system in people with HIV/AIDS and related conditions and to treat cancer. Beta glucans are also given intravenously to prevent infection in people who have undergone surgery.

Beta-glucans can be given by subcutaneously for reducing the size of skin tumors or for treating them.

In the food industry, beta-glucans are used as an additive in products such as cheese spreads, frozen desserts, salad dressings and sour cream.

Adding beta-glucans to your diet either in form of foods that contain the compound or in form of food supplements plays a significant role in boosting your immune system to help your body fight diseases.

How does beta-glucans work?

When taken by mouth, Beta-glucans lower blood cholesterol by inhibiting the absorption of cholesterol from food in the intestines and stomach. Beta-glucans stimulate the immune system by increasing chemicals that prevent infections when given by injection.

Studies by leading scientists and medical experts have shown that Beta-glucans act as immunomodulator agents by triggering events that regulate and increase the efficiency of the immune system. Beta-glucans stimulate the activity of immune cells that attack and ingest invading pathogens.

Immune cells such as Macrophages release cytokines that are chemicals that enable immune cells to communicate with each other. In addition, Beta-glucans increase the activity of white blood cells that bind to viruses or tumors, and release chemicals to destroy it. Beta-glucan is a biological response modifier that nutritionally activates the immune response through the Dendritic, Macrophage and other immune cells to produce various therapeutic effects.

The potential side effects of Beta-glucan when taken by mouth are unknown. When used by injection, Beta-glucans can cause fever, pain at the injection site, chills, vomiting, headache, nausea, dizziness, rashes, diarrhea, back pain, joint pain and low blood pressure.

Where does Beta-glucan come from?

The body does not produce Beta-glucan naturally; you can only get it from outside sources such as shiitake mushrooms, baker’s yeast and cereal grains such as wheat, oats, barley and rye.

The most potent form of beta glucan is extracted as a purified isolate from the yeast cell wall of Baker's yeast with harmful yeast proteins removed by a process that prevent clumping or reaggregation after exposure to water during digestion. Research has shown that Beta- glucan is a safe and potent immune potentiation isolate.


URL references

  1. //www.rxlist.com/beta_glucans/supplements.htm
  2. //www.med.nyu.edu/content?ChunkIID=104429
  3. //www.ncbi.nlm.nih.gov/pubmed/17895634
  4. //www.healthline.com/health/beta-glucan-heart-healthy

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EGCG in green tea
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Date: May 10, 2014 07:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EGCG in green tea

Green tea benefits

green tea leavesGreen tea is made from the leaves of Camellia Sinensis, which is recognized for its health benefits. The nonfermented product is obtained by leaf desiccation that contains potent, polyphenolic antioxidants, with a flavanolic structure referred to as green- tea catechins, including epigallocat-echin-gallate (EGCG). Studies have shown that drinking EGCG prevents carcinogenesis in rodent organs. Studies have shown it had a significant chemoprotective effect against DMBA-induced mammary tumorigenesis in rats. Human breast cancer cell proliferation inhibition by green tea appeared mediated in part by (CKI). Mutagenesis was inhibited at concentration levels equivalent to human daily consumption.

Using human umbilical vein endothelial cells, it was demonstrated that green tea extracts reduced expression of vascular endothelial growth factor (VEGF) receptors forms-like tyrosine kinase and fetal liver kinase. Kinase insert domain containing receptor. Because of the antiangiogenic property of its extracts, they have therapeutic potential in preventing the development of new microvascular networks (angiogenesis) needed for tumor growth. It was also found that green- tea polyphenols inhibited angiogenesis by reducing vascularization of chicken chorioallantoic membrane (CAM) by an angiogenin-like protein isolated from goat serum.

EGCG effectively inhibited bladder-tumor implantation growth in rats, pointing to its potential as an intravesical chemotherapeutic agent. Inhibition of platelet function is a factor in reducing the risk of coronary artery disease. EGCG was reported to inhibit platelet aggregation, by possibly involving inhibition of cytoplasmic calcium increase. EGCG was proven to be the most effective in reducing thrombin-induced aggregation of washed human platelets. The ability of green- tea catechins to inhibit adenovirus infection and adenain, the human adenovirus 2 endopeptidase, was reported. EGCG proved the most potent inhibitor of four green-tea catechins tested. The viral protease adenain appeared to be the target of EGCG, so it is possible that all adenoviruses are sensitive to its action.

The Chinese have known about medicinal qualities of green tea since ancient times, treating everything from headaches to depression.

The three "Es"

  1. enjoyment (soothing)
  2. energy (caffeine)
  3. essential health benefits (antioxidants)

Provides support for a healthy weight loss program, gives the energy needed to maintain an active lifestyle, health, and longevity. The appetite suppressor, Vanadium, reduces calorie intake. Thermogenesis, or fat metabolism, is increased, because of the EGCG/caffeine combination, therefore burning fat.

EGCG fights free radicals. Fatty acids and lipids in the brain are susceptible to the effects of free radical perodixation. Much of the aging of the brain is attributed to perodixation. The EGCG helps to keep us young, alert, and able. Researchers have found that EGCG has inhibited tumor growth in both skin and gastrointestinal tracts. EGCG may fermented be able to obliterate cancer cells, without harming neighboring tissues.

 

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Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes?
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Date: May 07, 2014 11:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes?

Glutamine

muscle glutamineGlutamine is considered to be the most abundant natural amino acids which is a building block of proteins in the body. Although the body can already make enough glutamine on its own, extreme stress is the type you could experience after heavy exercise or from injuries can't naturally aid help those pains on its own. The body may need a bit more glutamine in order to truly eliminate those kinds of ailments. Most glutamine is naturally stored in the muscles and lungs.

Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes?

Glutamine is also very important when it comes to removing excess ammonia which is a common waste that grows in the body. It has also been shown to help your immune system to function more normally to create proper brain function and bowel movements. Glutamine is naturally utilized at high rates by the isolated incubated lymphocytes that produces glutamate, lactate, and aspartate. The pathways for glutamine metabolism can include reactions catalysed by aspartate aminotransferase, glutaminase, succinate dehydrogenase, oxoglutarate dehydrogenase, fumarase, and phosphoenolpyruvate carboxykinase. Having high levels of glutamine in the body has been claimed to help improve the body's lymphocites and intestinal cell enterocytes in the body.

This is why numerous product contains a high levels of glutamine to help with imbalanced areas in the body. Purchasing the purest of glutamine products is the best way to get the most benefits out of it. Glutamine can also help increase the metabolism promoting a much easier time maintaining your weight. Increasing your glutamine can definitely do wonders for your daily life, as it will improve numerous aspects in your body.

In conclusion, be sure to boost your glutamine while your young so that when you get older, you body has a great storage of it when it may need the most.

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Facts about whey protein.
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Date: January 24, 2014 10:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Facts about whey protein.

Whey Protein

whey milkWhey protein refers to one of the two significant parts of milk, whey is the fluid parcel of the milk that divides from the curds (the other real part), throughout the process of cheese processing. Whey proteins are made up of fats, sugars, vitamins, and minerals. Because of its tough amino acid acerbic profile and simplicity of withholding, it is ostensibly the most prominent games nourishment supplement.

Whey protein exists in three principle structures:

Isolate, concentrate, and hydrolysate. This article will concentrate on how different is concentrate from isolate. Both structures have whey protein, but whey isolate, which is created out of whey concentrate, goes through further processing which yields an end product with more protein per unit than whey concentrate.

Then again, the whey protein isolation procedure is significantly more exhaustive. It basically differentiates the protein, just about in its sum from the crude whey, bringing about 90-94% pure protein. So in a 50-gram serving of whey protein isolate, move toward getting 45-47 grams of unadulterated protein with the remaining 3-5 grams being maybe 1 gram of crabs and some calcium, potassium and sodium.

You may tend to think that whey protein is spring water because as it is separated, pure and also healthy, yet contains the greater part of the minerals and so forth of regular water. While whey protein disengage is like refined water, as it is water in its purest structure with essentially all different particles evacuated additionally a hydrogen and oxygen atom

The essential distinction between isolate and concentrate

Isolate is the most unmodified type of protein. Whey isolate typically have between 90-94% proteins while whey concentrate has a protein proportion of around 70-85%.

In the event that you are you are not fit for lactose and you have issues with gas then the whey protein isolate is the better decision. Whey protein concentrate is also an astounding source of protein and concentrate has higher BV qualities contrasted with lean red meats, chicken, fish and entire eggs. Isolate whey is more expensive than other forms as Isolate has been filtered more than concentrate some of the important immune-boosting protein components have been removed and some say the protein is degraded more making it less useful to the body.

The following sites have more on whey proteins that every consumer should know.

References:

  1. www.allmaxnutrition.com
  2. www.2buildmusclefast.com
  3. www.bodybuilding.com


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How cat's claw as a natural immune system booster to treat and prevent diseases
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Date: November 01, 2013 07:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How cat's claw as a natural immune system booster to treat and prevent diseases

catsclawplant

What is cat's claw plant 

The root of the cat's claw plant, which is scientifically known as Uncaria tomentosa, contains compounds called pentacyclic oxindole alkaloids (POAs) that are responsible for its healing powers. The consumption of the cat's claw roots in raw or extract form must not be mixed with other foods that may neutralize the helpful effects of the POAs. The name cat's claw is Latin and represents this woody Amazonian vine that has only recently grabbed the attention of scientists who now use high performance liquid chromatography to see the POAs and isolate them for medicinal purposes. Here is an explanation of how the herb works to treat or prevent diseases.

What does cat' claw plant benefits

The alkaloids in the cat's claw herb are responsible for strengthening the immune system, but the specific benefits are as follows. In the digestive tract, the herb is able to treat Crohn’s disease, gastritis and duodenal ulcers, intestinal inflammation, parasites as well as balancing the intestinal flora. To the immune system itself, the herb stimulates the production of white blood cells to help combat arising problems of arthritis, rheumatism, chronic fatigue syndrome and infections by viruses or fungi. In South America, it serves as a birth control herb because of its associated properties of causing an unfavorable environment in the uterus thus preventing a fertilized egg from attaching to the uterus.

The anti inflammatory effects of the herb, together with its anti-tumor properties, all attributed to the alkaloids, prevent the damage of cells in the body by free radicals. As a result, patients having weak immune systems are able to significantly improve their chances of fighting diseases when they take in the herb as a supplement or tea. It’s the procyanidolic oligomers (PCOs) that stimulate phagocytes, which are special immune cells that destroy viruses and other organisms causing diseases. Excess use of cat's claw extracts or the herb itself can lead to nausea and headaches. The recommended dosage is 250mg of the extract taken twice in a day, or a teaspoon of cat's claw tea mixed with warm water, taken at most three times in a day.

References:

  1. //www.herbal-meds-online.com/Herbal-Meds/Cats-Claw-is-an-immune-boosting-herbal-supplement.html
  2. //voices.yahoo.com/boost-immune-system-cats-claw-209593.html
  3. //alternative-healthzine.com/una-de-gato-cats-claw/
  4. https://caworld48.wordpress.com/2013/10/20/what-are-the-health-benefits-of-cats-claw/

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What Are The Health Benefits Of Inositol Crystals?
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Date: December 28, 2012 10:39 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Health Benefits Of Inositol Crystals?

The first isolation of inositol was made by Scherer in the year 1849 who was a renowned Biochemist at the time. Since its discovery, wide spread research has been conducted with successful isolation of inositol and its derivatives in both plants and animals. The physiological functions have been confirmed to differ with respect to the structural form of the inositol, with cis-inositol, myo-inositol, neo-inositol and allo-inositol being some of the inositol's stereoisomers commonly isolated.

Our Need for Inositol

The human body particularly requires inositol and its derivatives in many physiological processes. It is a major messenger molecule that is used in calcium mediated cell signaling which affects motor function, action of hormones such aldosterone and affects the functioning of some of the neurotransmitters in the brain such as serotonin. Inositol derivatives are also involved in lipid metabolism which helps control the amount of LDP (Bad cholesterol) in the body.

Additionally, some of the researches indicate that inositol derivatives are actively involved in suppressing oncogenesis which significantly reduces the risk of suffering from breast and prostate cancers. The human body can produce some of the inositol variants from glucose metabolism but obtaining plant derived inositols is also worthwhile.

Food Sources Of Inositol

Plant products such as red beans, bran and other cereals contain good levels of inositol although the chelating effect of the inositol by calcium and magnesium ions limits its uptake in the gut. For this reason, use of supplement Crystal Inositols is regarded as the best way to obtain dietary inositol. A majority of the crystal inositols available in the market are chemically combined with other compounds such as Niacin which highly increase their absorption in the intestines. Dissolving these crystals in juices is also highly recommended as it is a better way of taking the supplements since a wide range of other drinks especially the ones that contain caffeine affects the uptake of inositol negatively.

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The Tremendous Health Benefits Of Omega- 3 Fatty Acids
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Date: November 10, 2012 11:53 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Tremendous Health Benefits Of Omega- 3 Fatty Acids

Omega-3 vs Omega-6

Several sources of information and clinical studies have revealed that the ratio between these two essential fatty acids in our diet have over a period of time played a significant role in making humans prone to certain diseases that the early humans were not afflicted with.

The raging debate in finding the right ratio arises also from the fact that modern foods preferences lean heavily toward the consumption of omega-6 rich foods . This fatty acid has been linked to the pathogenesis of cardiovascular diseases, cancers, inflammatory diseases, immunodeficiency, artherosclerosis, hypertension, blood pressure, arthritis, diabetes and obesity. In the last ten thousand years our genetic structure has remained the same, but with the onset of the Agricultural Revolution radical changes in food habits have created a lopsided diet. The western diet is heavily oversubscribing to the use of the polyunsaturated fatty acids or PUFA, and going low on Essential Fatty Acids or EFA. Living in the industrial societies that we do and in a kind of nutritional environment that we live in, we need to make informed choices about the food we consume is important considering how high- risk western societies are to many kinds of ailments.

Both omega-3 and omega -6 fatty acids are essential for us, but have to be obtained from food as the human body does not have the ability to produce it. Clinical evidence has shown that the Mediterranean diet is more focused on fresh fruits, vegetables, fats from olives, fish, nuts, garlic and whole grains. It has the requisite amounts of healthy fats to combat numerous diseases like coronary condition, rheumatoid arthritis, depression, high cholesterol, schizophrenia, inflammatory bowel disease, asthma, bipolar disorder and colon cancer. Astounding also is the finding that our body possesses a certain enzyme that can be linked in its structure and function to these essential fatty acids. These are called prostaglandins.

Prostaglandins

Prostaglandins are the end products of a chain reaction that begins with the release of unsaturated fatty acids from the cell membrane. It was first isolated from human semen and has found great use as an enzyme based treatment for menstrual problems, childbirth and many other medical conditions. Its ability to increase blood flow has resulted in its use for inducing abortion in troubled pregnancies. However, its over secretion in the body is related to numerous inflammatory conditions and has been found to increase in the body due to the overbearing presence of 0mega-6 fatty acids.These facts can not be taken lightly for a civilization reeling under the onslaught of devastating ailments. Its time to take heed .

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Lecithin And Its Brain Boosting Properties
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Date: March 02, 2012 07:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lecithin And Its Brain Boosting Properties

Lecithin

Lecithin is a group of fatty substances, which occur in the tissues of plants and animals. It composed of fatty acids, choline, phosphoric acid, triglycerides, glycolipids, B vitamins, glycerol, and phospholipids. Liver produces this substance daily if you follow a complete nutritional diet. Lecithin is also inevitable for all cells in your body,protecting your cells from oxidation, and it is a major building block of cell membranes. It also supports the circulatory system of your body because it is a fat emulsifier too.

Its Discovery

The first isolation of lecithin was done by a French pharmacist and chemist, Theodore Gobley in 1846 and he named phosphatidylcholine Lechithine in 1850. He isolated it originally from egg yolk. Today, lecithin can very easily be extracted mechanically or chemically from soybean, grape seed, and sunflower. However, in plants, the most common source of lecithin is soybean. This substance is used for medicinal purposes and as a food supplement. Sometimes, it is used as an emulsifier in cooking for preventing sticking.

Your body gets adequate amount of lecithin from your diet because it is naturally found in foods such as soybeans, egg yolk, peanuts, yeast, legumes, fish, wheat germ, grains, etc. It is also available in the market in the form of capsules, granules, and powder. This is also used as a supplement for promoting weight loss. Besides, you can also take lecithin in the form of pill or mixed in health shakes.

Health benefits of lecithin

It is believed that lecithin is beneficial for solving a number of health problems. So it is effective for:

* Cell communication,
* Healthy skin and hair,
* Improvement in memory, reaction time and learning,
* Treatment for gallstones,
* Reproduction,
* Child development,
* Fat metabolism and transport,
* Liver and cell function,
* Cardiovascular health,
* Relief of arthritis,
* Physical performance,
* Neurological problems,
* Treatment for memory disorders,
* Muscle endurance, etc.

Brain Boosting Properties of Lecithin

The major brain chemical for improving memory is acetycholine and the deficiency of this chemical is the major cause of declining memory. This chemical can be derived from nutrient choline. Fish is a rich source of acetylcholine. It can also be obtained from eggs, nuts, peanuts, soy beans, liver, etc. Eating more egg is beneficial for enhancing your memory.

There are lots of studies has been conducted for finding the effectiveness of lecithin in improving the memory. As per the findings of experts, lecithin is highly effective for improving concentration, memory, and for preventing Alzheimer's disease and maniac depression (bipolar disorder). Lecithin helps to run your brain smoothly by improving insulation around the nerves. A major part of cell membranes consists of lecithin and it is essential for the proper functioning and growth of nerve. Organ meats and egg yolks are rich sources of lecithin but the usage of these products is very less due to the fear of cholesterol. Experts think that this is the major reason for the increase of concentration and memory problems.

If you use lecithin properly, you can improve your concentration, memory, mind and nerves.

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Melatonin, Sleep, and insomnia
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Date: February 08, 2012 08:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Melatonin, Sleep, and insomnia

Melatonin history

The pattern according to which a human being wakes up and remains awake during the day and falls asleep at night is regulated by a hormone known as Melatonin. This hormone was first discovered by a team of researchers that was led by a Yale dermatologist by the name of Dr. Aaron Lerner. While Lerner passed away on the 3rd of February, 2007, however, his discovery was quite groundbreaking in medical science.

Initially back in 1958, the Melatonin hormone that was isolated from the pineal gland inside a frog's brain was believed to be a cure for skin pigmentation problems. However, it was later discovered that rather than helping to treat skin pigmentation problems, this hormone had a role in regulating the wake and sleep pattern of human beings. There, Dr. Aaron Lerner and his team of researchers came to conclusion that sleep related problems; especially insomnia could be treated using this hormone.

Sleep disorders

Almost millions of Americans these days are suffering from sleep disorders include insomnia, narcolepsy, etc. Insomnia, in particular, is not really a disease but is merely a disorder or a symptom that makes an individual sleepless and makes it difficult for them to fall asleep. In fact, people suffering from insomnia are hardly able to get any quality sleep, especially at night, which is most essential for them. Those people who have had a couple of sleepless nights can be certain that they are suffering from insomnia, however, people rarely visit a doctor when suffering from this sleep disorder.

There are a variety of reasons that cause insomnia. Anxiety, depression, discomfort, specific medical illnesses, stress, etc. are some of the most common causes of insomnia. Insomnia can last for both short and long periods of time. When it comes to safely treating insomnia, the melatonin hormone can be used for this purpose. Presently there are numerous natural melatonin supplements available in the market that can be used by insomniacs as a remedy for the sleep disorder they are suffering from.

It was somewhere during the mid 1990s when this hormone became available in the form of pills. At that time travelers who frequently suffered from jet lag used supplements containing this hormone.

Melatonin benefits

These days, after further research claims are being made that many other benefits are also offered by this antioxidant hormone. Research has proven that headaches and migraines, which are among the causes of insomnia, can be effectively relieved by using supplements containing melatonin. It is believed that the certain cancers can also be prevented from further developing with the help of this hormone.

As for insomnia, it is a sleep disorder that disrupts the natural sleep and wake pattern of the body. This hormone, therefore, restores that pattern back to normal causing people to feel sleepy at the right time when they actually need sleep. This sleep is being promoted by a natural hormone so these supplements cannot be considered drugs and neither do they cause an individual to feel as if they are drugged. Insomniacs will simply begin feeling naturally sleepy and this is why it is safe to use melatonin supplements to treat insomnia.

Give it a try and feel the difference

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How Does Serrapeptidase Support A Healthy Immune System, Regulate Inflammation, And More?
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Date: September 01, 2011 02:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Serrapeptidase Support A Healthy Immune System, Regulate Inflammation, And More?

What Does Serrapeptidase Do In The Body?

Serrapeptidase is an enzyme which is protein - digesting by nature. It is considered to be one of the types of proteolytic enzymes which consist of the chemical substance protease. This chemical is derived from a non - genetically engineered fungus of the family of Aspergillus. Serrapeptidase is a dietary supplement which may be isolated from Serrapeptidase oryzae and Serrapeptidase melleus. Studies have claimed that this dietary supplement is effective as an anti - inflammatory, respiratory aid, cardiovascular or immune support. Other names of Serrapeptidase include serration - peptidase and serrapeptase.

During the early 1990’s, Serrapeptidase was isolated from the microorganism Serratia marcescens which is a known human pathogen found in the digestive tract of the Japanese silkworm. Many studies have been conducted to uncover the medicinal purposes of this bacterial enzyme. In fact, it has been widely used clinically in specific areas of Asia and Europe primarily as an inflammation relief agent.

These are some of the uses of the enzyme Serrapeptidase:

1. ANTI – THROMBIC AND FIBRINOLYTIC. Serrapeptidase can significantly prevent the build – up of blood clots. These clots must not be accumulated to prevent thromboembolism which can cause life threatening health conditions such as heart attack and stroke. Aside from its ability to prevent clot formation, Serrapeptidase also has a good fibrinolytic ability. It can lyse or dissolve already – formed blood clots.

2. PH REGULATOR. This proteolytic enzyme is considered to be an alkaline metalloprotease enzyme. It can selectively act on specific biological systems and prevent the activation of immunoglobulin G and immunoglobulin A. These body chemicals are immune system factors which helps the body prevent from infections and illnesses.

3. GOOD PROTEIN DIGESTER. Clinical studies have revealed that Serrapeptidase has a very good ability to digest protein molecules and its substrates. This is the reason behind why Serrapeptidase can effectively dissolve protein – based tissues such as fibrins, blood clots, cysts and certain inflammations. The advantage of this enzyme is that it can dissolve unnecessary tissues without harming the normal living tissues.

4. PROFOUND ANTI – INFLAMMATIORY AGENT. Serrapeptidase can effectively prevent and reduce inflammation, thus reducing swelling and pain sensation. The mechanism of action is said to be that Serrapeptidase blocks the synthesis of pain – inducing amines. Another mechanism is that it can effectively inactivate pro – inflammatory chemicals known as cytokines. In fact, this chemical is one of the components of analgesic drugs in Europe. The positive effect of this enzyme is that it does not have any digestive side effects.

5. RESPIRATORY AID. This enzyme is also helpful in improving the health of the respiratory system. It effectively alters the elasticity and viscosity of the dense mucus in people with respiratory problem such as sinusitis, bronchitis, asthma, and pulmonary diseases. People who are taking this enzyme supplement have shown improved liquefaction and expectoration of the mucus, thus Serrapeptidase is considered to be an effective mucolytic agent widely used all over the world.

Serrapeptidase is generally safe. Clinical studies have revealed that the sources of this enzyme are non – pathogenic except of one strain known as Serratia marcesens. This strain is pathogenic to human body. It may cause hypersensitivity or any untoward signs and symptoms. Therefore, it is best to consult a doctor before starting such supplementation.

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How Does Malic Acid Help With Fibromyalgia?
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Date: August 22, 2011 12:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Malic Acid Help With Fibromyalgia?

Solaray - Malic Acid with Magnesium 90ct 133mgFibromyalgia(FM) is a condition affecting primarily middle-aged women and is often misdiagnosed and misunderstood as an ailment which has a diverse set of symptoms, in which none are pleasant. It basically is a medical disorder defined by chronic and widespread pain, a heightened response to pressure and often time painful as well. No one really knows what the exact causes are. There are a number of studies taking place and done by reputable medical organisations (such as the Nation Institute of Arthritis and Musculoskeletal and Skin Diseases - NIAMS) which are geared towards the establishment, once and for all, of the route cause of Fibromyalgia. A part of the current scientific theories is the inherent genetic factor, but even in this it seems that geneticists are not clear as to which genes exactly may be the culprit. What has been concretely established and clarified though is that not just because your mom or dad has it you’ll have it. Stress in some studies has also been found as a contributor but may not be the main cause though.

Malic acid is an organic compound and also a carboxylic diacid and is an active ingredient in many sour or tart foods. It is mostly in unripe fruits and it has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally. The salts and esters of this diacid are called malates. The malate anion is an intermediate in the citric acid cycle. However it was not until 1785 that Carl Wilhelm Scheele first isolated it from apple juice. It is formed in metabolic cycles within the cells of plants animals and humans. A somewhat large amount of Malic Acid is produced and broken down in the body each day. Malic acid also provides stamina and endurance within the muscle cells. It is particularly useful in the blocking of aluminum toxics, which has been found to possibly be one contributing factors to fibromyalgia.

Energy Production

Compelling evidence has surfaced that malic acid may plays a central role in energy production, especially during hypoxic conditions. In some experiments that have been done, the improvement that came about when malic acid was administered to the subject was gone after discontinuing for 48 hours. The theory behind this is in the relative association of hypoxia to FM, if it will improve hypoxic conditions then it will be beneficial for FM sufferers as well just as Chronic Fatigue Syndrome has also been associated with FM. Additionally, many hypoxia related conditions, like respiratory and circulatory insufficiency, are related to deficiency in energy production as well. Therefore, malic acid may be of benefit in these conditions.

The mitochondria are the energy furnaces in cells which metabolize food for energy. Some findings suggest that this structure does not operate efficiently in those with FM. So, for the mitochondria to produce ample amounts of ATP, several nutrients are essential and Malic Acid is one of them. Imbalances in the mitochondria’s process can cause the body to switch from oxygen-based metabolism to the less efficient anaerobic metabolism and this would contribute to an abnormal buildup of lactic acid following even light exertion. This lactic acid buildup results in fatigue, weakness, pain and muscle spasms.

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How Does Grapefruit Seed Extract Help Fight Candida Yeast Infections?
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Date: August 08, 2011 06:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Grapefruit Seed Extract Help Fight Candida Yeast Infections?

Grapefruit seed extract is processed from the seeds, pulp, and vesicles of the sour citrus fruit known as grapefruit. Nutrition experts have attributed several medicinal properties to the plant. In addition, practitioners of herbal medicine make use of the seeds and membranes of the fruit in health tonics. It has long been linked to the treatment of earache, sore throat, digestive problems, and yeast infections.

Citrus x paradisi is a hybrid species of pomelo and orange. Its fruits are much larger than oranges but smaller than pomelos, growing up to 15 centimeters in diameter on average. It is widely known as a naturally occurring hybrid, like sweet orange. The juice of popular varieties of the fruit comes in colors red and pink in respect to its ripeness. Some cultivars are sweet, but most are sour at the same time.

Many organic compounds isolated from grapefruit have long been observed to show pharmacological activity. For one, consumptions of the fruit itself have been reported to interact with numerous drugs. It either enhances the potency of drugs or inhibits their pharmacological activities. Researchers have enumerated a long list of drugs whose bioavailability increase in the presence of grapefruit extracts.

Proponents of grapefruit seed extract believe that it possesses antibacterial, antiviral, and antifungal properties. They began promoting its medicinal uses at the turn of the 20th century. At that time, physicians took note of the many benefits tied to grapefruit in the earlier century. Furthermore, they produced the first extracts from the seeds and white membranes of the fruit mixed with glycerin.

Grapefruit seed extract is an all natural remedy for Candidiasis. As its name suggests, Candida yeast infections are caused by different species of fungi that belong to the genus Candida. These fungi are part of the normal flora of the human body that comprises bacteria and other microorganism. While they are not harmful in general, they are capable of producing harm and spurring inflammation.

Oral thrush is one form of Candidiasis that infects mucus membranes located in the mouth cavity. Populations of yeast build up in the surface of the mouth and bring on inflammatory responses. The infection often appears as cream-colored deposits or slightly raised red patches. Candidiasis of the skin, sex organs, and other parts of the body look similar as they are all inflammatory in nature.

The effectiveness of grapefruit seed extract in the treatment of Candidiasis yeast infections has been compared to conventional medications. Its use is supported by anecdotal evidence that is largely positive. While the results of studies are conflicting at best, researchers have compared the extract to benzethonium chloride, a chemical compound that displays strong antibacterial and antifungal activity.

Grapefruit seed extract is a viable remedy for Candidiasis yeast infections. In fact, it may be used as a therapeutic prophylactic for infections caused not only by fungi but also viruses and bacteria. Due to its putative effect, it is added as an active ingredient to many personal care products.

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What is Red Marine Algae And What Are Its Health Benefits?
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Date: June 01, 2011 04:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Red Marine Algae And What Are Its Health Benefits?

Red Marine Algae And Your Health.

Red marine algae refer to a large group of seaweeds that contain phycobiliproteins, which give them their red coloration. They are simple organisms in that they do not have complex tissues in contrast with terrestrial plants. Many species of red marine algae plays an important role in the formation of coral reefs as they secrete calcium carbonate as well as provide nutrition for other marine species. Like plants, they are capable of making their own food by way of photosynthesis. And like most other seaweeds, they are excellent sources of vitamins, minerals, and other healthy organic compounds.

Scientific Classification

Rhodophyta is the taxonomic classification of all red marine algae. It is oftentimes considered a part of the plant kingdom, but more recent definitions of plant suggest red algae belong to a kingdom of their own. Rhodophyta is one of the largest groups of algae, second only to green algae. It consists of up to 6000 aquatic species that are widely distributed in the tropical, temperate, and even frigid zones. These species usually take up residence along the coastal regions and significantly contribute to the distribution, abundance, and ecology of organisms found in the extended perimeter of each continent.

Historical Uses

Seaweeds have become a part of the staple diet of many communities throughout history, and red marine algae are one of the best sources of human nutrition among all seaweeds. For thousands of years, different species of red algae have enjoyed significant presence in cuisines from all over the world. It is often consumed uncooked or added to salads. It is also an important ingredient in soups and stews. Ocean farmers have learned different techniques of domesticating crops of algae, and cultivation has been the solution to the growing demand of red marine algae in the past few decades.

Industrial Applications

Red marine algae have steadily grown in economic value since the 20th century. In addition to their historical culinary uses, their application now extends to medical science. Several organic compounds have been isolated from different species of red marine algae are now in wide use in the food and drug industries. For example, gelatinous substances are derived from agarophytes, any species of seaweeds that belong to rhodophyta. These substances are used in the production of beer, food preserves, ice cream as well as papers, fabrics, lubricants, and other personal care products.

Medicinal Value

Red marine algae have a special place in antiviral research. Many species are now identified to contain organic compounds that are of medicinal value against several viruses. Decades-long studies have come to a conclusion that sulfated polysaccharides derived from red marine algae have an inhibitory effect on replication of herpes simplex virus (HSV). There is good evidence that one class of sulfated polysaccharides called carrageenan offer some protection against transmission of herpes. Furthermore, recent studies have revealed that sulfated polysaccharides are potent inhibitors of HIV-1 in cell culture.

Red marine algae is an excellent source of nutrients found in the sea. Get some red marine algae and reap the benefits of this nutrient rich food today!

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Agave Nectar
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Date: April 08, 2010 04:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Agave Nectar

Agave Nectar Light Certified Organic 17 oz from NOWComments by Craig Gerbore, CEO of Madhava:

Reading through the attack articles and blogs that have surfaced recently one could think that using agave is bad for one's health. These claims are utterly false and misleading. They are extreme views drawn from extreme examples and applied way out of context. They are propagandizing and clearly designed to frighten, not educate. All of the fears and concerns associated with the overconsumption of sugars and calories in general have been unfairly cast on agave.

What is a "healthy" sweetener? One that you use moderately and sensibly.

Health concerns related to fructose and caloric sweeteners are all dependant on the overconsumption of them. All foods have calories and it is the overall consumption of calories that lead to obesity and related issues, not any one food source.

Agave's caloric value is comparable to the other sweeteners in the category. Due to its greater sweetness though, less agave is used compared to the others, so agave actually can reduce caloric consumption per serving. This is due to a higher fructose content. The higher content does not mean higher consumption though, due to the smaller portion used. But, it is not the single serving that matters, it is the number of servings which lead to the overconsumption issues which may result in health concerns.Agave Nectar Amber Certified Organic 17 oz from NOW

As a reference point, 9-10 teaspoon servings of agave would be the approximate caloric equivalent of one 16 oz soft drink. With this perspective, is agave really being overconsumed as a choice of sweetener for home use?

Every single health issue which the attackers have tried to associate with agave is really the result of a caloric overconsumption issue. There are no documented issues with normal, moderate consumption of agave or sweeteners in general as part of our everyday diet. For reasons unknown, some have attempted to isolate agave from the real world and real world conditions with the goal of inhibiting agave's use. They play on people's fears, reference false information and fail to address health issues in any meaningful way.

The purpose of this article is to debunk the controversial misinformation surrounding agave. All information debunking the myths and misinformation is based on current science and facts. It is our goal to provide you with useful information so that you can make your personal nutritional choices in a well-informed, science-based manner.

The Agave Controversy: Exposing the fraudulent article by Rami Nagel

By Dr. Susan Kleiner, PhD, RD, FACN, CNS, FISSN

And Craig Gerbore, CEO Madhava

The controversy about agave syrup was manufactured by the publication of a single article on the internet, which has been reproduced and adapted for virtually every other article produced on the internet and other media venues. That article, written by Rami Nagel and published on Naturalnews.com, was highly biased and full of inaccuracies, half-truths and misinformation about agave. Since the Naturalnews.com article has been the sole source of nearly all other popular articles in public media, we want to set the record straight with science-based, reliable information to offer a more balanced resource to those interested in learning more about agave syrup. Organic Blue Agave Nectar 16 Liq from FunFresh Foods Who is the author, Rami Nagel?

According to the description on the Naturalnews.com website, Rami Nagel is a "citizen journalist". This means that Mr. Nagel is self-employed, and not employed as an in-house journalist by the website. He wrote and published the article without any editorial or content oversight, and the editor of the website, Mike Adams, makes it clear that the article was not checked for incorrect or inaccurate information or facts. The introduction to the article, written by Mr. Adams, states that readers had written to comment that Mr. Nagel's resources were biased with conflicts of interest due to their financial interests in competing sweeteners, such as brown rice syrup. So even the website editor himself states that the article is not fact-checked, and it is biased and unbalanced.

Who is Russ Bianchi?

The sole resource interviewed for the article is Russ Bianchi, identified by the author as Managing Director and CEO of Adept Solutions, Inc. Mr. Bianchi has clear conflict of interest ties to the sweetener industry. We have documentation of the fact that Mr Bianchi had plans to market a product named Replace. It was to be touted as a low calorie alternative sweetener composed of natural and artificial ingredients! Mr Bianchi was prevented from marketing this sweetener as the result of a lawsuit against him by the owner of the formula.

Mr Bianchi is quoted by Nagel extensively and exclusively. Many, if not all, of his statements are blatantly false or misrepresentations of fact. He is clearly propagandizing against agave nectar.

Was anyone else interviewed for this article?

Yes. Craig Gerbore, president and owner of Madhava Agave Syrup, was extensively interviewed by the author but no parts of that interview were included in the article. Organic Maple Agave Nectar 16 Liq from FunFresh Foods

It is important to note that neither Mr Nagel or Mr Bianchi have not made themselves available for questions on their statements since the articles appearance. They remain out of sight and have entirely avoided the controversy their statements created.

What is agave nectar?

The opening line of this paragraph in the article by Mr. Nagel states:

"The principal constituent of the agave is starch, such as what is found in corn or rice."

This is absolutely false. There is no starch in agave. The source of carbohydrate in agave syrup is inulin, a polysaccharide made up primarily of strings of fructose units. Starch is a polysaccharide made up of strings of glucose molecules. They are significantly different, and this difference is why agave syrup is naturally sweet.

The very basis of the argument presented by Mr. Nagel is false.

The Process

The agave plant is a succulent, similar to a cactus. The agave sweetener comes from both the Salmiana agave plant and the agave Tequilana (Blue Agave) which are both organically farmed in Mexico and certified organic by USDA approved certifiers. As the salmiana plant grows it produces a stalk called the "quiote" and when this is removed, a natural liquid called "aquamiel". The liquid is collected from the plant, while Blue agave pinons are harvested and shredded to remove the similar juice. Either can be naturally processed thermally or by enzymes into agave nectar.

The juice of the plant is not naturally sweet. The string of connected fructose units that makes up the major proportion of inulin does not have a sweet taste, but when the fructose units are separated (the process is called hydrolysis) by the addition of an enzyme, similar to digestion, or thermally for most blue agave, the syrup becomes quite sweet. That is the entire processing chain for agave nectar. There are no additives, other ingredients or chemicals in Madhava agave nectar. It is absolutely pure and organic and GMO free.

? Mr. Nagel claims that agave syrup is a "refined corn fructose" similar to high fructose corn syrup. This is absolutely false. There is no relationship between agave syrup and high fructose corn syrup in any way, including the source of the product, or the manufacturing process.

? Mr. Nagel refers to a "confidential FDA letter" from Mr. Martin Stutsman, claiming that agave is fraudulently labeled. We contacted Mr. Stutsman at the United States Food and Drug Administration, and his response made it clear that there was never a "confidential FDA letter". He did publish a public letter referenced in an FDA document as "FDA letter from Martin Stutsman to Dr. Eric

Wilhelmsen (Wilhelmsen Consulting), May 8, 2000", regarding evaporated cane juice, a topic wholly unrelated to agave syrup.

? He continued in his response to us that the paragraph in Mr. Nagel's article inaccurately reflected the substance of his comments in the document.

This link will take you to the original document in which the letter was referenced (reference #2):

//www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/FoodLabelingNutrition/ucm181491.htm

In fact, Mr. Nagel fabricated the entire story of the letter. Mr. Stutsman is a lawyer, not a doctor. The quotes were completely taken out of context from the document, and the quotes never referred to agave syrup at any time. Nagel goes on to further misrepresent Mr. Stutsman's intent in the published document by weaving in other inaccurate information that is thoroughly unrelated to the original document. Mr Bianchi's subsequent statements on labeling issues are false and without merit.

Mr. Nagel is clearly caught red-handed. He has misrepresented the words of a government official, lied about the facts, and twisted the information to achieve his own agenda. This strategy is repeated throughout the article.

? Mr. Nagel continues his deceptive writing by referring to a quote by the late Dr. Varro Tyler in his book, The Honest Herbal. The first line of the paragraph is a direct quote from the book. Nothing else in that paragraph remotely resembles anything else found in Dr. Tyler's book. Mr. Nagel is trying to claim that agave syrup contains large quantities of saponins, and that they can be harmful to health. Here is the debunking of that paragraph:

1. Dr. Tyler does not include the variety of agave plant used for agave syrup.

2. The entire discussion is about the use of the sword-shaped leaves and the stem. Agave syrup is produced from the natural liquid in the plant. The saponins are isolated from the leaves of the plant.

3. There is no documented evidence to suggest agave syrup contains worrisome levels of saponins and the entire rest of the discussion about health dangers is fabricated and false.

Sugars

People are going to continue to consume sweet food and drink. There are only three categories of choice to sweeten food. Those are artificial sweeteners, stevia, or caloric sweeteners from natural sources, sugars.

Most people will not choose artificial. Many will not choose stevia. That only leaves the category of sugars. In this group, agave is a good choice due to its organic quality, ease of

use, neutral flavor, low glycemic index and the fact that less is used to equal the sweetness of the others in the category.

The sweeteners in this category are composed of three primary sugars used to sweeten foods: glucose, fructose and sucrose. These sugars belong to a class of compounds known as carbohydrates. "Saccharide" is a term that denotes sugar, or substances derived from sugar. Monosaccharides are simple or single sugars; disaccharides are derived from two joined monosaccharides and when they are hydrolyzed, or separated, they yield two molecules of simple sugar. Strings of more than two sugar molecules are called polysaccharides. This category includes compounds such as starches, cellulose and inulin.

Glucose and fructose are monosaccharides. Glucose and fructose are found abundantly in nature in fruits and plants. Sucrose is the disaccharide formed by the joining of glucose and fructose, also known as table sugar. When comparing their relative sweetness, glucose is the least sweet tasting, sucrose is next, and fructose is the sweetest of the three sugars, measured as 1.4 times sweeter than table sugar. Because it is so sweet, people typically use less fructose when sweetening foods compared to sucrose.

? In the article by Mr. Nagel he states , "fructose is not what is found in fruit. Commonly, fructose is compared with its opposite and truly naturally occurring sweetener, known as ‘levulose' (made by nature)..."

Another fabrication. In fact, levulose is just another name for fructose. There are various nomenclatures used in the scientific naming of compounds. Fructose and levulose are exactly the same thing; the names are interchangeable. It is no different than if you called your father, "dad", and your sibling called your father, "father". He would still be the exact same person. Fructose and levulose are different names for the exact same thing: a sugar found in nature.

Mr. Bianchi also is quoted to say that the body does not recognize the fructose in agave. This is another false piece of propaganda which demonstrates just how far he is reaching. If this were true, it would have no impact on us. He immediately contradicts himself with the claims of detrimental effects caused by the overconsumption of fructose.

Using Sugars

Sugars can be compared to each other in their ability to raise blood sugar levels by using the Glycemic Index. The scale is set from zero to 100, where low numbers do not have much impact on blood sugar levels, and high numbers raise blood sugar levels quickly. Fructose is very low on the scale. Because agave syrup is high in fructose, it has a rating of 32 or lower. Honey, which has a higher proportion of glucose to fructose, has a Glycemic Index of 58. Sucrose has a Glycemic Index of 68, and glucose, serving as the index standard, is 100.

All sugars, whether fructose, glucose, sucrose or others, contribute 4 calories per gram to our total diet. 1 teaspoon of sugar = 4 grams = 16 calories

In addition to calories, sugars sweeten our foods offering a desirable taste and adding enjoyment and pleasure to our dining. During cooking and baking, sugars allow for browning and the unique consistencies of syrups, candies, frostings and frozen desserts. The varieties of sugars, such as crystallized table sugar, brown sugar, raw sugar, molasses, honey and agave nectar, among others, contribute different properties and flavors to foods.

When you add your own sugar to foods you are in control of how much sugar you use. Most people would never add as much sugar as do the food manufacturers. Moderate amounts of sugar can certainly be enjoyed as part of a healthy diet for an active individual. Natural sugars are easily metabolized and utilized by the body, offering a very efficient source of fuel for physical and mental activity.

Of course, sugars should be used in moderation in the diet. This can control calories and help create a diet that is dense in nutrients.

Impact of sugar on health and disease

? The remainder of Mr. Nagel's article works to link agave syrup with the increased incidence of obesity, diabetes, metabolic disease, and the general rise of morbidity and mortality in the population. This is an overconsumption issue involving far more than the occasional use of agave. Here are the facts:

• Rats that are fed a high fructose diet become obese and will develop the chronic diseases associated with obesity: insulin resistance, diabetes and metabolic disease.

• No one should eat a diet that reflects this type of experimental diet.

• Too much sugar in the diet, whether from fructose, glucose or sucrose, can be unhealthy. Diets high in sugar promote tooth decay and periodontal disease; create an overabundance of calories and a deficit of nutrients. This scenario typically leads to weight gain and the development of chronic disease.

• Active individuals can include a moderate amount of added sugar in their diet without negative health consequences. When calorie intake is balanced with physical activity, sugar serves as an efficient source of fuel for muscles, the brain and the central nervous system.

• According to the World Health Organization (2003), individuals can healthfully include 10% of their daily calories from added sugars. This translates into 200 calories for a 2000 calorie diet, or 12½ teaspoons of added sugar daily. Clearly, one can safely add a couple of teaspoons of sweetener to a cup of tea or coffee, or have a little sweetened food without worrying about their risk of developing disease.

• Agave syrup, which is sweeter than other sugars and low on the Glycemic Index scale, is a good choice to include as one of the added sugars in your diet because you will use less sugar (and therefore fewer calories) and minimally raise blood sugar levels.

Just a teaspoon of agave: the healthy use of sweeteners in your diet

We all want to live healthier and longer lives. Diet and nutrition plays a key role, impacting our health and our ability to perform physically and mentally now and into the future. Food offers us not only sustenance, but also pleasure and enjoyment. Food is present in so many parts of our lives: at celebrations, business events, family events, religious and spiritual occasions, sports outings, the focus of our family meals, intimate dinners, and sometimes just the excuse to socialize.

Sweet foods make us feel good. Sugar allows for the elevation of serotonin in our brains, the "feel good" neurotransmitter that elevates mood, helps us focus, and in the evening, helps us relax and sleep.

Sugar is a source of energy for our muscles, brain and central nervous system. Without sugar our bodies will not function at peak capacity.

Too much sugar, however, is not good. In small amounts sugar energizes us, but in large doses, repeated throughout the day, day in and day out, sugar puts stress on the body. The extra calories can lead to weight gain and obesity, which in time can lead to chronic disease. In the short term, high sugar intakes can lead to a nutritionally deficient diet and a sense of being on an emotional roller coaster.

So be selective about your use of sugars and use them in moderation in your diet. Just like all foods, a variety will enhance the nutritional content of your diet and the flavor and tastes that you can enjoy. Since sugars come in different forms and have different flavors, they can be used most effectively in specific foods and beverages. For instance, agave syrup is liquid and less viscous than honey, making it easy to mix into cold liquids like iced tea and coffee, and is great to add to cold unsweetened cereals for a little sweet taste. Agave's mild flavor allows chefs and bakers to sweeten foods lightly, without overpowering the taste of the dish.

Pay attention to how much sugar is added to your diet every day. Read labels so that you know when sugar is added to manufactured foods. Keep the consumption of added sugars in your diet to no more than 10% of your total daily calorie intake so that you have plenty of room for nutrient dense foods like fruits, vegetables, grains, dairy, protein-rich foods, nuts, seeds and healthy oils.

Remember that nutrition is a science based on facts. We are making great advances in our understanding of the science of foods and nutrition. Beware of people with hidden agendas using fear tactics to influence your choices. Don't take their opinion at face value. What are their credentials? What conflicts of interest do they have? If they do not disclose conflicts, then assume that they are manipulating the truth.

Most of all enjoy food. Think about what you need to eat to promote whole health. Don't overindulge, but don't deprive yourself of the bounty of wonderful tastes, either. Use celebrations as occasions to enjoy your favorite foods and try new ones. A teaspoon or two of sugar easily fits into the diet of an active, healthy person. Agave syrup offers an organic low-glycemic choice for those looking for that option.

Resources for this article:

Charley H. Food Science, 2nd Edition. John Wiley & Sons, New York, NY, 1982.

Figlewicz DP et al. Effect of moderate intake of sweeteners on metabolic health in the rat. Physiology and Behavior 98:618-624, 2009

Johnson RK et al. Dietary sugars intake and cardiovascular health: A scientific statement from the American Heart Association. Circulation: Journal of the American Heart Association, 2009

Tyler VE. The Honest Herbal, Third Edition. Pharmaceutical Products Press, New York, NY, 1993.

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Pine Bark Extract
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Date: October 07, 2009 11:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pine Bark Extract

Pine Bark PictureMany Native American tribes relied on the bark of pine trees for its ability to treat a number of disorders. The Annedda pine was called the “tree of life” due to its marvelous healing benefits. Jacques Cartier, a noted explorer in 1535, wrote in his diaries about the early medicinal uses for pine tree bark. Cartier and his crew came down with scurvy after being caught in the bitter snows of Quebec and living on hard biscuits and cured meat. Multiple men died before Quebec Indians approached them and made a tea from the bark of a pine tree. After drinking the tea and applying poultices to their wounds, they were soon healed. The miraculous recovery is actually a result of the vitamin C and bioflavonoids in the bark. A French professor discovered Cartier’s account and became intrigued with studying pine tree bark. He isolated a certain kind of proanthocyanidin flavonoids from the extract and later found it to have antioxidant attributes.

Pine bark extract has become an important herbal remedy due to its antioxidant power. It is responsible for binding with collagen fibers and helping to restore elasticity in the skin. It also protects the body from free-radical damage, which prevents excess and premature wrinkles. Pine tree bark also protects capillaries from free-radical damage that can cause phlebitis, varicose veins, and bruising. Those people who are suffering from skin conditions like psoriasis can also be benefited from pine bark extract. Along with being an antioxidant, pine bark is a natural anti-inflammatory. It helps heal joint pain that is associated with things such as arthritis and sports injuries. This herb helps to control and prevent edema and bursitis. Pine Bark Picture Pine bark extract also helps with eyesight. It is responsible for reducing the risk of and treating diabetic retinopathy. Multiple studies have concluded that it is beneficial in improving night vision. One study even found marked improvement in visual performance in the proanthocyanidin group over a placebo group.

Additionally, pine bark extract may also help in inhibiting cellular mutations like tumors. Reports have found that this herb can help to prevent cellular deterioration in breast tumors and cardiovascular disease. There is also evidence that this herb possesses antiulcer properties that may help prevent the formation of undesirable chemicals in the stomach.

Pine bark can also benefit other conditions with its proanthocyanidin therapy. Among these are autoimmune disorders such as lupus, neural problems such as Parkinson’s disease and multiple sclerosis, and vascular problems like heart disease, atherosclerosis, and stokes. Pine bark extract can also treat common complaints such as insomnia, flu, and even the common cold. This herb is very helpful in improving memory, longevity, and the prostate.

Additionally, its stimulant properties are responsible for decreasing the production of histamines in allergic reactions like hay fever. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by pine bark extract, please feel free to consult a representative from your local health food store with questions.

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Ginseng, Its Good For The Body
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Date: October 05, 2009 11:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ginseng, Its Good For The Body

Ginseng, one of the oldest and most beneficial herbs in the world, is probably the most popular herb used in traditional medicine. It was rated the highest and most potent of herbs in Shen-Nung’’s Pharmacopoeia in AD 206-220. People in northern China began using ginseng thousands of years ago. Early herbalists recognized the shape of ginseng as resembling a human figure, feeling this was a sign that the root was important for healing the entire body. Often, ginseng is referred to as the “man root” and is often the subject of many legends and fold history. The Chinese revered the ginseng root so highly that they even fought wars over the land used for growing this herb.

There are many different types of the ginseng plant that are grown throughout the world and used for traditional medicine. All of the most common species of plants known as ginseng have similar reactions in the body. Ginseng has often been referred to as an adaptogen herb, helping to normalize and adjust the body. This herb also restores and regulates natural immune response. Ginseng helps produce adjustments as needed in the body without side effects or harm. This herb has been used to help normalize blood pressure. This adaptogen helps to modify the effects of the environmental and internal stresses from various sources like chemical pollutants, radiation, some poisons, weather, temperature changes, poor diet and exercise, and emotional stress. Used for many ailments, ginseng is thought of as a universal cure-all, promoting longevity in general.

A great variety of studies have been done in many countries to determine the effectiveness of ginseng. In some instances, incomplete results have occurred. However, there have been enough credible studies done to now determine that high-quality ginseng plants do contain active constituents that are very beneficial to the body. Research has even shown that the roots are effective against bronchitis and heart disease.

There has been a lot of interest in the alleged aphrodisiac effects of ginseng. Often marketed as a sexual stimulant, the results of most studies have been inconclusive. Ginseng does increase the sperm count. For thousands of years, ginseng has been used to strengthen the male reproductive system. It is highly recommended alone or in combinations for both male and female health.

Ginseng contains at least thirteen known triterpenoid saponins, which are referred to as ginsenosides. These are thought to be the most important active constituents. Many other minor components have been isolated as well. The age, location, species, and curing method of each plant effects the composition. Some of the plants tend toward stimulating and warming effects, while others have relaxing and cooling effects.

The root of the ginseng plant is used to provide adaptogen, alterative, aphrodisiac, stimulant, and stomachic properties. Primarily, ginseng is extremely beneficial in dealing with age spots, appetite loss, asthma, high blood pressure, and depression, lack of endurance, fatigue, fevers, hemorrhage, hormone imbalance, sexual stimulation, and stress.

Additionally, this herb is very helpful in treating aging, anemia, bleeding, blood diseases, bronchitis, and cancer, lack of concentration, gastric disorders, indigestion, inflammation, impotence, insomnia, liver disorders, and lung disorders. For more information on the many beneficial effects provided by ginseng, please contact a representative from your local health food store.

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Detoxify With L-Citrulline
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Date: April 13, 2009 03:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Detoxify With L-Citrulline

L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood.

It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea.

The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea.

The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-hydroxyarginine, and then into L-citrulline with the release of nitric oxide.

So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells.

Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred.

In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure.

Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery.

During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow.

It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels.

It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid?

Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise.

Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted.

Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.

L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.

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Detoxify At Vitanet ®, LLC

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Hoodia Gordonii
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Date: December 10, 2008 10:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hoodia Gordonii

Hoodia Gordonii is a South African succulent plant of the family Apocynaceae. They are remarkable similar in appearance to cacti, although they are totally unrelated to them and grow predominantly in the region of Central Namibia in the south west of Africa, up to the southern regions of Angola. They are most commonly found in rocky ground and on the plains.

There are several species of hoodia, some of them grown domestically, and it is Hoodia gordonii that is used as an appetite suppressant in hoodia weight loss pills. Although the plant has historically found use in the treatment of infections and gastric problems, most interest is displayed in its use by the bushmen of the Kalahari Desert to suppress their appetite during long hunting trips when food and water are scarce.

The active ingredient was isolated in 1977, and given the name P57: the product is therefore often referred to as Hoodia P57. It was patented by its discoverers, the CSIR (South African Council for Scientific and Industrial Research) and a license granted to UK company Phytopram, who worked together with Pfizer to isolate the active ingredients and manufacture them synthetically. This was found to be very difficult, if not impossible, since any synthetic form of the extract failed to display any hunger-suppressant properties.

Finally, the rights to the main ingredient were released by Pfizer in 2002, thus indicating that it was of no commercial benefit to them. The main problem they admitted with synthesizing P57 was not only the difficulty in doing so, but also that there were side effects of the extract on the liver caused by other components that could not be removed. No synthetic form of hoodia is therefore available, and only the natural plant is used in current Hoodia 57 preparations.

The rights of the San Bushmen to the plant were recognized by the CSIR in 2002, and not only do they receive a proportion of the profits of marketing hoodia, but also the plant is protected with wild-harvesting licenses provided to only certain individuals and companies. Due to the rising popularity of the hoodia weight loss industry, the plant has been named as an endangered species in the wild.

It is believed that the active ingredients are steroidal saponins that can fool the body into believing it is full. This theory is based upon the effect on appetite of glucose concentrations in the blood. Your appetite is controlled by the amount of unconverted glucose in your blood, and glycogen in the liver. When you eat carbohydrates, they are digested and converted into glucose which is absorbed into the bloodstream.

Under normal conditions your blood glucose levels increase to a level where a signal from hypothalamus stops you feeling hungry. Insulin is then secreted from the pancreas to prepare your cells to use that glucose in the mitochondria to create energy by means of the Kreb's Cycle, or Citric Acid Cycle as it is also known. This reduces the concentration of glucose in the blood, and once it reaches a certain level the body begins to use its emergency energy supply, glycogen, that is stored in the liver.

A signal then informs the brain that more glucose is needed. You then feel hungry again, and this cycle is repeated several times a day in a normally healthy person. This cycle is controlled by certain hormones in the brain, specifically in the ventromedial center of the hypothalamus, where it is believed that the ATP (adenosine triphosphate) availability controls the release of the hormones involved.

ATP is the molecule of energy, and as the concentration of blood glucose and of glycogen drop, then the amount of ATP produced also drops and this is detected in the hypothalamus, which reacts by releasing ghrelin. Increased leptin increases the feeling of satiety and ghrelin increases the feeling of hunger. Serotonin acts on the brain to increase the effect of leptin in the hypothalamus, and therefore make us feel less hungry, or more satiated.

It is believed that hoodia gordonii, or the Hoodia P57 component of it, fools the brain into believing that your blood glucose or glycogen levels have reached the point at which it should trigger a satiated response, so that you stop eating even though your ATP levels might be low. The steroidal saponins that it contains is believed to be ten thousand times more effective than glucose in stimulated the secretion of serotonin.

Hoodia has also been found to contain a number of glycosides, including pregnane glycosides that some studies have indicated to help control appetite of the subjects tested. Most of these tests have been carried out on animals, although Hoodia weight loss preparations are offered in a form standardized on both steroidal saponins and pregnane glycosides.

Hoodia gordonii is becoming so popular as a weight loss product that its export is being monitored by the South African government. It has become so endangered that, since 2005, only hoodia grown on commercial farms is permitted an export license, and exporters must obtain a license from the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Importers also require a permit from the US department of Agriculture, and a CITES certificate is also needed to re-export the finished product.

Because of this, more hoodia weight loss pills are being sold than there is hoodia gordonii to produce them. It is not uncommon for cacti such as the prickly pear cactus from Mexico, to be used, or for low concentrations of hoodia to be bulked up with fillers. Neither of these is of any use as an appetite suppressant, the former having no active ingredients whatsoever and the latter containing only traces.

If you are purchasing hoodia, therefore, be aware of this. Request sight of the CITES certificate and USDA permit, and also the analysis results by an authorized laboratory to confirm that the product is what it purports to be. Otherwise, there is some evidence that Hoodia gordonii can help you reduce weight, although to date there are only four recognized analytical laboratories registered to analyze the active content of hoodia weight loss products.

Finally, check for the analysis certificates. All Hoodia weight loss products should be analyzed by each of three methods: Microscopy, High Performance Thin Layer Chromatography (HPTLC) and High Performance Liquid Chromatography (HPLC) - all there are needed. The four authorized laboratories are: the University of Mississippi, Chromadex labs in Irvine California, Alkemist Pharmaceuticals and Advanced Laboratories, Smithfield, NC.

No others will do, so if your Hoodia weight loss preparation has not been analyzed using the three methods by one of these laboratories, don't buy it, even if it can show the CITES and USDA documentation.



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Buy Hoodia At Vitanet ®, LLC

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NOW® Introduces Genuine Whole Food™ Labeling
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Date: September 27, 2008 01:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NOW® Introduces Genuine Whole Food™ Labeling

NOW is excited to highlight our line of Genuine Whole Food products with a new icon. These existing products include a wide range of items, including NOW® Flax, Alfalfa Juice, Blue Green Algae, Kelp, Spirulina, Aloe, Hoodia, Colostrum, and Chlorella. One of the most exciting to join this new product category is an Organic Red Yeast Rice that is sourced right here in the United States.

In order to provide you and your customers with the finest possible product, these items undergo a delicate process that helps retain the highest concentrations of nutrients and other beneficial extracts. They are minimally processed without adding or creating new isolates, and we do not spike our active ingredients. This results in safe ingredients that provide nutrients in their original form. NOW® Genuine Whole Foods are concentrated using only deionized water; no harsh chemical solvents are used at any stage during the process.

When it comes to the products that enter your body, natural is always better. Not only are natural products free of potentially dangerous chemicals, they also contain a wide range of nutrient compounds that cannot be recreated in a laboratory. All NOW Genuine Whole Food supplements are 100% natural and free of artificial colors, flavors, sweeteners, and preservatives. Our new Genuine Whole Foods icon identifies this commitment made to product quality. Each product delivers a ratio of nutrients similar to that found in natural food sources. This results in greater nutrition that your body can use in the most effective manner possible.

Unlike other companies that offer only a small selection of Whole Food-based products and ingredients, or none at all, NOW has a diverse selection of 68 SKUs that encompasses a wide range of health and wellness needs.

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Hoodia Extract And Appetite
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Date: September 26, 2008 11:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hoodia Extract And Appetite

Hoodia is a plant that belongs to the milkweed family and consists of about twenty different species. It is a leafless, spiny plant, with fleshy finger-like stems. Along the stems, there are rows of thorns, while the plant bears flesh-colored flowers. Flies are attracted to the flowers by the strong smell of decaying meat, causing the flies to lay their eggs and pollinate the flowers. Sometimes spelled hootia, hodia, hoodie, and hudia, hoodia has recently gained a great amount of attention in the United Kingdom and America after being featured on BCC and CBS. Often growing in summer rainfall areas in Angola, Botswana, Namibia, and South Africa, along with winter rainfall areas in Nambia, hoodia gordonii is the only species that contains the chemical component that suppresses appetite.

Hoodia has been used for thousands of years by San Bushmen, as it populates the arid territories of South Africa and Namibia. Because San Bushmen needed to remain active in order to survive, they had little need for dieting, but this plant provided them with stamina and a curbed appetite during long periods without food. Along with reducing or eliminating the desire for food, many people believe that hoodia also increases energy and can act as an aphrodisiac on the user.

The appetite-suppressing ingredient found in hoodia is a molecule that is similar to, but stronger than glucose. The active compound that was isolated to be responsible for appetite suppression is P57, which works by sending a signal to the hypothalamus of the brain, tricking the body into thinking that it is no longer hungry, and resulting in a complete lack of appetite. P57 is a steroid like molecule that is chemically bonded to a chain of three sugar molecules. The appetite-suppressing and mood-enhancing properties of P57 go directly to the mid-brain, where it causes neuron cells to fire as if you were full.

The hypothalamus is the region of the brain that contains several important centers which control body temperature, thirst, hunger, water balance, and sexual function. Additionally, the hypothalamus is closely connected with emotional activity and sleep and also functions as a center for the integration of hormonal and autonomic nervous activity through the control of pituitary secretions. In short, the hypothalamus links the nervous system to the endocrine system. The pituitary gland is often thought of as the mater gland in our bodies, as the anterior and posterior pituitary secrete a variety of hormones that influence all cells and affect almost all physiological processes.

The pituitary gland is powered by the hypothalamus, as some of the neurons in the hypothalamus secrete the hormones that are responsible for controlling the secretion of hormones from the anterior pituitary. The inhibiting and releasing hormones of the hypothalamus are carried directly to the anterior pituitary where hypothalamic hormones bind to receptors on anterior pituitary cells.

The P57 hormone that is found in hoodia works by increasing the amount of ATP in nerve cells found in the hypothalamus. ATP is an energy-producing molecule that is formed from glucose. When there are increased levels of ATP in hypothalamic nerve cells, those nerve cells fire as if you had just eaten, even when you haven’t. Hoodia is a safe herb taken for hundreds of years, have you tried Hoodia lately?



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Panax Ginseng
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Date: September 22, 2008 09:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Panax Ginseng

Panax is a type of perennial plant with fleshy roots, and grows in Eastern Asia. Ginsengs contain ginsenosides that are triterpene saponins, steroidal compounds that are found only in Panax ginseng. The effects of these saponins are difficult to establish, but they are believed to be behind the properties of ginseng.

Panax ginseng is found predominantly in Korea, China and Siberia, although a genus has also been found in Vietnam. Panax are adaptogenic herbs that help promote resistance to anxiety, fatigue and stress, and are said to adapt the body to resist a number of different stressors. It has been proposed that adaptogenic herbs can balance the endocrine hormones of the hypothalamus, pituitary and adrenal axis.

They also normalize the immune system, and increase the activity of phagocytes, the killer cells. Additionally, they not only help to maintain homeostasis, but are believed to go further and act as allostatic agents, adapting response to maintain system stability in a more dynamic fashion, by changing interactive functions as opposed to the individual adaption’s made in homeostasis.

Not all ginsengs are the same, and although Siberian ginseng is an adaptogen, it is not a true ginseng. Its roots are woody rather than fleshy, and it contains eleutherosides as opposed to ginsenosides. These also are triterpenoid saponins, but of a different adaptogen. The herb is actually Eleutherococcus senticosus as opposed to Panax ginseng and P. quinquefolius, both true ginsengs. Siberian ginseng was misnamed as a marketing ploy.

American ginseng is Panax quinquefolius, sometimes referred to by the Chinese as Huaqishen. It, too, is an adaptogen and a true ginseng, containing ginsenosides. However, it contains much less ginsenonide Rg1 than panax. This ginsenonide appears to possess estrogen-like activity and improves spatial learning. The other forms of ginesonide found in panax ginseng are:

Ginsenoside Rb1: This appears in greatest concentration in American ginseng, and appears to have an effect on the reproductive system. It not only has an effect on the testicles, but is believed to increase testosterone production through its stimulating effect on luteinizing hormone. It also helps to rdeduce the incidence of angiogenesis, which is the formation of new blood vessels from old, and also a stage in the development of malignant tumors from dormant ones.

Ginsenoside Rc: this possesses sedative properties, and in a study on breast cancer was found to have an effect in inhibiting the growth of these particular cancer cells. Ginsenoside Rc might therefore have use in the treatment or prevention of breast cancer. Studies have also suggested that this ginsenoside could increase the motility of sperm: the motiliy of sperm was found to increase significantly in a solution of ginsenoside Rc.

Ginsenoside Rf: this is present only in panax ginseng, and studies have indicate that it has an inhibitory effect on the Ca2+ neural channels in the brain, and so cokld have an analgesic effect. Studies have as yet failed to explain this effect that is seen in animal tests, but are continuing on this ginsenoside.

Ginsenoside Re: this ginsenoside has strong antioxidant effects and has a significant antidiabetic effect in that is reduces insulin resistance, which is likely why ginseng is taken to treat Type 2 diabetes. Studies are ongoing into the properties of this ginsenoside, and also on the other 10 or more that are known to be present in Panax ginseng. The effects of ginseng are difficult to establish with certainity because they work through so many different pathways and it is difficult to isolate one. More than one ginsenoside, for example, affects the calcium channels in the brain, and it is difficult to determine which does what.

There are fewer ginsenosides in Panax quinquefoilius, and in the USA it is only the panax version that can be traded as simply ‘ginseng’. One of the main problems with all ginsengs is that although it is one of the most studied plants, the majority of the studies have been on animals, and due to this, and the difficulties caused by the multiple pathways described earlier, many of the postulations have not been proved in humans.

However, if the theory as it is know today is taken into consideration along with the traditional uses of ginseng in traditional Indian (ayurvedic), Chinese and Native American medicine, it would be fairly accurate to say that ginseng is useful in helping your body to recover after illness or surgery, and to help you to deal with stress. It has also been proved to lower your blood glucose (sugar) levels, and help in the treatment of Type II diabetes, as already mentioned. There is evidence that it helps to boost your mental performance, memory and might help to slow down the onset of Alzheimer’s disease.

Ginseng can also give a boost to your energy levels, and it is genarally accepted that panax ginseng is more effective than the American version. In traditional medicine, Asian ginseng is said to be warming, and the American variery cooling. Thus Panax ginseng is useful for people recovering from illness and trying to recover their strength, acts as a tonic, stimulant and supports the immune system. In other words it helps the body to get whole again after being depleted.

It should not be used if you get very hot and red, such as with heat stroke, unless you use it in combination with the American version, because these are conditions of high yang and this type of ginseng will increase the yang even further.

American ginseng, on the other hand, is good for those with fevers, hypertension (high blood pressure), and suffereing the effcts of heat. It helps build the yin and reduce the yang, so if you always feel flushed and hot or are hyperactive then go for the American, and if you easily get chilled or find your hands and feet get cold very easily, reach for the Asian ginseng to increase your yang.

You often find ginseng as an ingredient in soft drinks, but the concentration is so low that it has no metabolic or pharmacological effect. The dose to be taken should be as stated on the pack, since there is no specific standardization. It has been noted that the effects can be lost if an excess of ginseng is taken, but generally the herb is safe and if you feel a bit down or lacking in energy, ginseng can work wonders for you.




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Antioxidants
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Date: August 14, 2008 09:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants

Antioxidants are the body’s main defense against free radicals as they work against the substances that create oxidants and the reactive substances that result from oxidation and reduction. Antioxidants neutralize free radicals by supplying the missing electron so that the molecule may be stabilized. There are many different types of antioxidants ranging from dietary antioxidants to those that the body produces itself. The four major antioxidant nutrients are vitamin A (beta carotene), vitamin C, vitamin E, and selenium.

Vitamin A, the first vitamin to ever be isolated, is essential for the proper function of the eyes and maintenance of the skin. It is found in the retina of all mammals as well as the liver. Vitamin A works to increase our resistance to infections by keeping all the linings in the body healthy. It is necessary for the health and moisture of the skin and the specialized cells lining the eyes, nose, mouth, throat, lungs, esophagus, stomach intestines, and urinary tract. When these cells don’t have sufficient vitamin A, they thicken and harden, which is extremely detrimental to health and makes us more susceptible to infection. Vitamin A also protects the body from cardiovascular disease and cancer, and is necessary for new cell growth, something that is extremely important in slowing the aging process.

Beta carotene is the best known of the two carotenoids that form vitamin A, being composed of two vitamin A molecules that are split apart by liver enzymes when the body is low in vitamin A. If body levels are sufficient, the enzymes remain inactive and beta carotene does not divide, making it a safe source of vitamin A, without producing the toxic effects that come with high levels of vitamin A itself. If excess beta carotene is consumed it is stored in fat tissue or circulated in the blood. Beta carotene is one of the most powerful antioxidant nutrients as it can prevent free radical formation and inactivate existing free radicals. Once free radicals have been formed, it traps them and breaks the chain reaction that occurs.

Vitamin C holds a crucial role in many body processes that are necessary for life, among these being its role in collagen formation. Collagen is important in the every structure of the body, as it works like glue to bind cells together to form tissues. The integrity of collagen depends on vitamin C. Vitamin C also functions as one of the most powerful free radicals to prevent the damage that contributes to aging and age-related diseases.

It also works against pollution and toxins that damage cells and cause mutations, possibly even reducing some food carcinogens and protecting lung lining fluids against damage by air pollution. Vitamin C is important in the immune system and it also increases immunity to infectious diseases, lowers total cholesterol, enhances the effect of vitamin E, promotes wound healing, growth, tissue repair, and helps with the utilization of iron.

Vitamin E prevents aging by prolonging the useful life of cells found in the body. It also works to protect vitamin C and vitamin A from free radical activity so that they may remain potent. Vitamin E has the ability to stop a free radical chain reaction as it is happening and plays an extremely important role in preventing the per-oxidation of lipids (cholesterol). It protects the cell membrane, which in turn causes it to help protect the body from disease.

Selenium, one of the ten essential trace minerals, can be found in all tissues of the body. It is best known for its antioxidant role and its function in fighting cancer. It protects the liver from damage and works to stop lipid per-oxidation. Selenium is vital in maintaining the elasticity of body tissues and preventing the oxidation of fatty tissue, in turn combating the effects of aging. Selenium causes the skin to be healthier, muscle mass and tone are more easily maintained, and the heart is strengthened. Selenium works along with vitamin E, enhancing the effects of each other. It is important to get our vitamins and minerals on a daily basis to maintain a health happier life.

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Vitamin C
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Date: August 12, 2008 01:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C

Vitamin C is the most widely taken nutritional supplement on the market and is available in a variety of forms, including tablets, drink mixes, crystals in capsules or bulk powdered crystals. Vitamin C is present in mother's milk and, in lower amounts, in raw cow's milk, with pasteurized milk containing only trace amounts. This vitamin is most present in the liver and least present in the muscle but needed through out the body.

Vitamin C is required for the synthesis of collagen, an important structural component of blood vessels, tendons, ligaments, skin, and bone. Vitamin C can regenerate other antioxidants such as vitamin E; in the body vitamin E can regenerate C as well. This vitamin is required for the growth and repair of tissues in all parts of your body. Relatively large doses of vitamin C may cause indigestion, particularly when taken on an empty stomach.

It has been shown that smokers who have diets poor in vitamin C are at a higher risk of lung-borne diseases than those smokers who have higher concentrations of Vitamin C in the blood. Biological tissues that accumulate over 100 times the level in blood plasma of vitamin C are the adrenal glands, pituitary, thymus, corpus luteum, and retina.

Studies suggest the presence of large quantities of sugar either in the intestines or in the blood can slow absorption of this vitamin. Several studies have demonstrated a blood pressure lowering effect of vitamin C supplementation. Also, when consumed in high doses it appears to interfere with the blood thinning effects of warfarin by lowering prothrombin time, as noted in case reports in the 1970s so consult your doctor if on medications..

In one Study, researchers instructed patients with documented coronary artery disease to take a single oral dose of either 2 g vitamin C or a placebo. Results, the researchers discovered that high doses of vitamin C can help prevent blood platelet sticking and fight cholesterol oxidation. Also, researchers discovered this vitamin can reduce the formation of potentially carcinogenic nitrogen-containing compounds in the stomach, offering protection from stomach cancer, researchers have reported.

French and German researchers found that vitamin C appeared to keep cells in the blood vessel wall from dying. The researchers, who studied immune indicators, such as serum immunoglobulin and neutrophil phagocytosis (how well your white blood cells can engulf and digest foreign bodies), concluded that vitamin C exerts a remarkable immuno-modulating action, in other words, improved immune function in all those who consumed vitamin C on a regular basis.

What are deficiency symptoms for vitamin C?

Scurvy is a disease resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function. Scurvy was common among those with poor access to fresh fruit and vegetables, such as remote, isolated sailors and soldiers. The amount of vitamin C required to prevent “chronic disease” appears to be more than that required for prevention of scurvy which is 30 – 60 milligrams per day. Based on scientific research, vitamin C also appears to improve oral absorption of iron, which is good news for those that are anemic.

Half of us in the United States will die from heart disease. The foundation of heart disease is atherosclerosis, the narrowing of our arteries with plaque. Treatment with vitamin C has consistently resulted in improved dilation of blood vessels in individuals with atherosclerosis as well as those with angina pectoris, congestive heart failure, high cholesterol, and high blood pressure. Researchers believe this protection from cell death could explain previous study findings which suggest that vitamin C benefits blood vessel function in people with congestive heart failure.

Vitamin C supplements are also generally regarded as safe in most individuals in recommended amounts, although there are rarely reported side effects including nausea, vomiting, heartburn, abdominal cramps, and headache. In addition, this vitamin is required for the synthesis of l-Carnitine, a small amino acid that is essential for the transport of fat to cellular organelles called mitochondria, for conversion to energy. If you have chronic fatigue syndrome, vitamin C may help by boosting energy production through the mitochondria.

Therefore, as in many studies of vitamin C intake and cardiovascular disease risk, it is difficult to separate the effects of vitamin C on stroke risk from the effects of other components such as diet and the consumption of fruits and vegetables. As with all dietitians an emphasis on the benefits of a diet rich in fruits and vegetables is important to maintain a healthy cardiovascular system. If one can not consume fruits and vegetables on a daily basis then supplementation of vitamin C is need in either capsule of tablet to fight the risk of disease.

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Cat's Claw
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Date: August 06, 2008 11:21 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cat's Claw

Traditionally, Cat's Claw has been used to treat arthritis, gastritis, tumors, dysentery, and female hormonal imbalances. Today, the plant has shown the ability to treat viral infections, minimize inflammation, and provide therapeutic action for stomach and bowel disorders including arthritis, Crohn’s Disease, ulcers, gastritis, parasites, diverticulitis, hemorrhoids, several types of cancer, irritable bowel syndrome, herpes, allergies, lupus, diabetes, PMS, yeast infections, hypoglycemia, prostatitis, bursitis, and rheumatism. European studies are currently looking at Cat's Claw for its ability to treat AIDS and cancer. Additionally, the herb has been used for Athlete’s Foot, Ear infections, back pain, TMJ syndrome, fibromyalgia, canker sores, sinus infections, and asthma.

Peruvians have trusted the anti-inflammatory abilities of Cat’s Claw for many generations, as it was traditionally used for any type of rheumatism or arthritic joint condition. Many studies on the plant metabolites found in Cat’s Claw have found that it does inhibit inflammatory response for a fact. The plant sterols that are found in Cat’s Claw have the ability to reduce artificially induced swelling. After extensive research, scientists have found that the strong anti-inflammatory activity is due to the presence of all the compounds together. These same compounds have an intrinsic anti-inflammatory effect as well.

These findings confirm what herbalists have advocated for many generations: the fact that plants are designed to be used in their whole form in order to be biochemically effective. Pharmaceutical synthetic versions of herbal medication shave so many bad side effects because they have been chemically extricated and isolated, which eliminates the very crucial role of other compounds that are vital to the function of the plant.

Natural botanical remedies, on the other hand, have been designed by nature to work together. Natural anti-inflammatories are extremely important for treating diseases such as allergies and arthritis because they have a lot less side effects than the prescription NSAIDs that are currently being used by thousands of individuals. Back pain, joint pain, inflammation caused by histamine release, and a whole lot of other maladies have resulted in millions of dollars worth of anti-inflammatory drugs such as ibuprofen to be purchased.

Diseases such as AIDS and flesh-eating viruses have received a good amount of press coverage over the last several years. Although a lot of us may not feel immediately threatened by these viruses, we may not be as strong as we could be immunologically. Most of us are battling a never-ending list of ailments such as colds, flu, sore throats, earaches, athlete’s foot, yeast infections, chronic fatigue syndrome, herpes, and colitis.

With heart disease, cancer, and diabetes being responsible for thousands of deaths each year, our country as a whole is in poor health. Our immune systems, which are our build-in defense mechanisms, need to be kept in optimal working condition as infectious microorganisms and carcinogens constantly surround us. A healthy immune system has a great ability to fight off disease or at least minimize its stay in our body. By fortifying our defenses with certain herbs, vitamins, and antioxidants, we can greatly promote wellness in our bodies.

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Butcher's Broom Extract
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Date: May 02, 2008 11:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butcher's Broom Extract

Butcher’s broom (Ruscus aculeatus) is a member of the lily family, and looks a bit like a holly bush with barbed evergreen leaves and bright red berries in the fall. At one time they were collected, tied together and sold to butchers as brooms to sweep out their shops.

The stiff leaves were particularly suitable for cleaning out offal and other waste products from butchered animals and also for scrubbing butcher’s blocks. It was also used as a deterrent to rodents with their eyes on the meat! Alternative names are sweet broom, kneeholy and Jew’s myrtle, so named because it was used during the Feast of the Tabernacles as one of the ‘four species’ used in the lulav.

The herb was commonly used in Ancient Greece and Rome, the Greeks using it to reduce swellings of various kinds and the Romans using it to treat varicose veins. It has the same uses today, only the mechanisms are understood better. It has been used for centuries in the Mediterranean area for the treatment of inflammations and problems with the circulation, and the Romans used to mash up the leaves and berries to add to wine, and they also used the roots and rhizome as a medicine by soaking them in wine. Today, it is illegal to use holly as a decoration in Italy, so butcher’s broom is used instead.

All parts of the plant are used, including the rhizome, and although it is used as a diuretic, and to control a loss of blood pressure experience by some people on standing up, it is its effect on blood vessels where its main medical benefits lie. Butcher’s Broom can strengthen certain portions of blood vessels, and change the flexibility properties of the cell walls.

The result of this is that the vessels are tightened up, which helps to maintain the flow of blood throughout the body, but also renders the cell walls less likely to leak or crack under stress. The result is a reduction in blood leakage from stretched and weakened blood vessels such as those that result in hemorrhoids, and also of conditions caused by weakened valves in the veins such as varicose veins and spider veins.

The blood pressure in the veins is very weak since they are so far away from the heart, the blood having passed through the arteries, through the capillaries and into the veins on its way back to the heart before being pumped to the lungs. When the valves become weakened, particularly in the large veins in the leg, there is little to prevent the blood from coming under the influence of gravity and pooling back down the vein, causing distention and occasional ruptures.

A ruptured varicose vein can be very serious and cause significant blood loss. Weakened valves can also lead to the formation of blood clots, which is itself a very serious condition that eventually blocks the heart or causes a stroke. Not only can butcher’s broom strengthen the vein walls and prevent leakage, and also enable them to more easily resist the pressure that can cause them to rupture, but it can also be used to break down blood clots. In fact the herb is used in many European hospitals to prevent the formation of blood clots after surgery.

The active ingredients in the rhizome are saponins that contain the aglycones ruscogenin and neuroscogenin and the associated spirostanol and furostanol glycosides. The receptors that cause vasocontraction are known as adrenoreceptors, these receptors can be selectively stimulated by butcher’s broom extract to tighten the veins and improve the return of blood. When introduced intravenously, butcher’s broom was noted to constrict venules (small veins that feed the main veins but not arterioles (the small arteries than feed the capillaries). Hence blood vessels can be selectively treated, and the effect on isolated blood vessels was enhanced by heating. Many supplements include calcium that helps to strengthen the blood vessel walls.

It is possible, therefore, to target the blood vessels that require constrictive treatment in order that they are strong enough to return blood to the heart rather than leak or distend. However, that is not the only health benefit that butcher’s broom provides. It can also be used as a diuretic. It is not a strong diuretic, but is used to relief the swelling of bruises and PMS, the reason given being that since leakage from the blood vessels is lessened, then more fluid is available to pass through the kidneys. There might be other reasons.

It is also use for the treatment of ortho static hypotension, the reduction in blood pressure that some people experience. It is believed that butcher’s broom can control this condition without increasing blood pressure, as most other remedies do, and which is almost as undesirable as the condition they are treating.

There are few problems associated with the herb, although few studies have been carried out its use by pregnant women. Although the one test that was carried indicated no effect, it would be wise for pregnant or nursing women not to use it until further studies have been carried out. Due to its effect in tightening blood vessels, its use is not recommended by anybody suffering from high blood pressure (hypertension). Many hypertension treatments are designed to render the blood vessels more elastic rather than constrict them.

In one very small study of pregnant women who used a topical cream containing butcher's broom, no side effects were seen for either the mother or the baby. However, very little information is available on how oral butcher's broom might affect a developing fetus, an infant, or a small child. Therefore, its use is not recommended during pregnancy, while breast-feeding, or during early childhood.

Because it tightens blood vessels, butcher's broom may worsen high blood pressure or benign prostate hyperplasia (BPH). Individuals with either of these conditions should not use any form of butcher's broom without first consulting a doctor. The known side effects have already been stated, and they are fairly mild, but few studies have been made on the herb other than in Europe, and the side effects have not been fully explored. It is unlikely; however, that there are any as yet unknown serious side effects since butcher’s broom has been used now for a long time, particularly in Europe.

The term ‘ruscogenin’ is used for the collective mixture of active saponins in butcher’s broom, and many of the supplements are formulated to include from 5 to 15 mg of these. However, check the label, since standardization is not yet required in the USA, and in theory a preparation can include much more or much less ruscogenin. It is frequently supplied with other active ingredients, such as vitamin C or calcium, and perhaps even horse chestnut that affect blood vessels in a similar way. Always follow the instructions on the package, since these are designed for the specific strength of supplement you are using.

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L-Carnitine For Health And Wellness
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Date: April 16, 2008 03:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: L-Carnitine For Health And Wellness

Research continues to mount evidence that l-carnitine can help boost energy and quality of life. Carnitine comes from the Latin word for flesh: caro or carnis. L-carnitine was discovered and isolated from meat in the early 1900s. At that time, scientists thought that l-carnitine played a role in muscle function; this was many years before technology would advance so that this theory could be proved. Today, we know that this amino acid is found mostly in tissue of the body that requires lots of energy such as the heart, skeletal muscles, and liver.

L-carnitine is considered a non-essential amino acid since the body manufactures it from l-methionine and l-lysine. Depending on one’s diet, the body manufactures most of, not all, the l-carnitine it needs every day. There are circumstances where a rare genetic disease can cause the body to not manufacture its own l-carnitine resulting in a deficiency which can cause secondary diseases such as cirrhosis of the liver, chronic renal failure, diabetes, heart failure or Alzheimer’s disease. Some medications can cause a deficiency as well, check with your doctor about prescriptions.

The primary energy source for the body is long-chain fatty acids. L-carnitine plays an essential role in energy production process. This amino acid transports long-chain fatty acids into the mitochondria, where it is used to produce energy for each cell in the body. l-carnitine then removes the “acyl” group by products out of the mitochondria as they accumulate. Both the transporting in and out of the cells mitochondria is vital for continued muscle function to occur.

Researchers suggest that the limiting factor in high intensity exercise is from the availability of l-carnitine in the muscle tissue. Studies conducted with this amino acid suggest that athletes experience improved performance when supplementing with l-carnitine by reducing post exercise lactate acid levels and improving recovery from exercise stress.

Some research suggests that l-carnitine can help chronic fatigue individuals by shuttling long-chain fatty acids into the mitochondria where the body manufactures energy. The bulk of this research was done on chronic fatigue patients who consumed 2 grams per day of l-carnitine. Additional research was performed on individuals over 100 years of age and the results were these individuals experiences increase physical endurance and improved cognitive activity.

L-carnitine can help cardiovascular conditions including angina, congestive heart failure, and peripheral artery disease. Recent studies showed male fertility improvement when l-carnitine was consumed on a regular basis. Men participating had better sperm motility which increases the changes of one reaching an egg and improving the odds of fertilization.

Research also demonstrated that 1 gram of this amino acid daily over three months can help one reduce weight by improving fat metabolism. This holds consistent with the findings that l-carnitine transports long-chain fatty acids (fat) into cellular mitochondria so it can be burned as energy. With a good diet and exercise plan, reports suggest that even more weight loss can be achieved.

Safety is of particular concern when adding extra supplements to one’s diet such as l-carnitine. Good news, l-carnitine is very safe at 1 – 3 grams each day, even higher doses are safe with no side effects. With the mounting evidence on the benefits of l-carnitine consumption, what is stopping you from adding l-carnitine today to your supplement diet to improve health and wellness?

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Third- The Science (Putting It All Together) Boswellia & Inflammation
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Date: April 03, 2008 12:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Third- The Science (Putting It All Together) Boswellia & Inflammation

Frankincense has traditionally been used in Ayurvedic medicine for centuries, and is even mentioned in the Bible. The trunk exudes a resin containing mono- and sesquiterpenes that possess powerful anti-inflammatory properties. They are also well known antiseptics and astringents, and support the immune and respiratory systems.

These terpenes are commonly referred to as boswellian acids, and consist of a carboxylated pentacyclic triterpene with at least one more functional group. Both the alpha and beta acid have a hydroxyl (-OH) grouping, and there are also the acetyl (CH3CO-) equivalents with an acetyl group replacing the OH. There are other so-called-boswellian acids, and it is believed that they all play a part in the anti-inflammatory properties of the resin.

The acetyl derivatives are thought to be involved in the death of some cancer cells, particularly those involve in brain and colon tumors, and also leukemia. The way in which they achieve this appears to be a programmed progression that ends with the dying out of the cells rather than a violently destructive mechanism, which lends credence to the Ayurvedic belief that the treatment is a natural one designed by nature.

The anti-inflammatory properties of the acetyl triterpenes are due to their effect on leukotrienes that sustain the inflammatory reactions of many allergic reactions and also of asthma. They appear to inhibit the enzyme elastase in leukocytes; this is a crucial enzyme in the production of the chemicals that promote inflammation.

It has been established that the inflammatory response of the immune system is due to the action of specific enzymes, so it stands to reason that if you can inhibit these enzymes, then you will also inhibit the immune response to specific initiators and so reduce the pain involved. Bosellian acid in the form of triterpenes appears to contain these inhibitors, and this would appear to explain its effectiveness. Pinene and phellandrene are among the terpenes isolated from Boswellia.

A standardised dose of 60% - 65% of Bosellian acids is generally used, so if you are purchasing Boswellia this is what you should be looking for. Keep in mind that it is intended to treat inflammation, ands that inflammation is an indicator that something with your body is not quite right. Therefore, while inflammation is painful, and Boswellia may help, you should also treat the cause of the inflammation by treating the immune system.

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Urinary Incontinence and Overactive Bladder: The Silent Conditions
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Date: February 07, 2008 05:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Urinary Incontinence and Overactive Bladder: The Silent Conditions

Even though we are all comfortable talking about cardiovascular issues, mind and brain function, and digestive wellness, the topic of bladder health is rarely discussed. Whether it is vaguely touched upon or completely ignored, bladder issues including urinary incontinence and overactive bladder get a low amount of coverage considering their prevalence throughout the world. Research has shown that 17 million Americans can be diagnosed with urinary incontinence and 33 million Americans suffer from overactive bladder. So with these figures, why is it that we rarely hear about these issues? Firstly, urinary incontinence and overactive bladder have been marked as taboo topics, as sufferers are not eager to openly talk about their experiences since they can be uncomfortable and embarrassing to discuss. Due to the social stigma that is associated with urinary incontinence, it is extremely under-diagnosed and under-reported. Another reason why people aren’t talking about bladder issues is because the market has only recently become recognized as financially viable as the market for urinary incontinence treatment reached more than $7 billion by the end of 2006, as compared to $276 million in 2000. With the new baby boomer population turning 60 in a few years, it is anticipated that urinary incontinence and overactive bladder treatment will soar much higher.

No matter the reason, these are serious health issues that affect people deeply. Both physiological and psychological aspects take their toll on a person. Studies have shown that people with these illnesses have a poorer quality of life, causing sufferers to become reclusive and isolated as they are too embarrassed to talk about their bladder issues.

However, there are a variety of ways that bladder health can be addressed, including pharmaceutical, behavioral, and natural approaches. Various drug therapies have been found to improve bladder control. However, most drug therapies also have unpleasant side effects such as dry mouth, dry eyes, blurred vision, and memory loss. Some drugs can even produce harmful long-term side effects. National continence groups also have recommendations as to behavioral interventions and exercises that can be taken to deal with bladder issues. Bladder control training, which involves teaching the bladder to completely fill and empty, is important to adequate fluids and avoid going to the toilet just in case. Kegal exercises can also be done to help strengthen the muscles that contract if you are urinating.

There are also natural herbal and nutrient options that are worth considering. These include Horsetail and Crateva nurvala, which both are means of improving bladder tone and control. Horsetail, which is high in silica, is known as a urinary astringent and antispasmodic. It relieves involuntary muscle spasms. Crateva has been shown to improve bladder tone and total bladder capacity. It improves urine flow, which helps the bladder to empty completely.

Since bladder health is a concern for many Americans, as it impacts what we do, where we go, our confidence levels, and sense of freedom, we need to start openly discussing bladder health and become more informed about the options that are available to us. Even though sufferers have learned to live with poor bladder health, recent research is making natural dietary ingredients an alternative for those who are looking for support to their bladder health.

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OptiMSM
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Date: June 26, 2007 02:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: OptiMSM

Eighty percent of Americans over 50 years old suffer from some form of degenerative joint disease, and many others suffer from sports injuries, tennis elbow and tendonitis, which can result in symptoms not unlike arthritis—soreness, stiffness, and general pain in the region. An ever widening number of people are newly discovering a well-established natural remedy for these symptoms—and numerous others—with MSM.

Methylsulfonylmethane (meth-l-sul-fonil-meth-ane), or MSM, is a natural nutrient found in many foods and is a vital building block of joints, cartilage, skin, hair and nails. It also supports a wide number of biochemical processes in the body, including energy production.

Due to the demineralization of the earth over time, many naturally occurring elements—including MSM- are not available in foods in high enough quantities to deliver therapeutic value. As a dietary supplement, MSM must be synthesized. When made correctly, it is identical to what is found in nature, and can be taken alone or in combination with other health supplements.

According to Stanley W Jacob, MD, Ronald M Lawrence, MD, PhD, and Martin Zucker, authors of The Miracle of MSM, MSM is rapidly establishing a reputation as a safe, natural and effective solution for many types of pain and inflammatory conditions, including degenerative wear-and-tear arthritis, rheumatoid arthritis, chronic back pain, chronic headaches, muscle pain, Fibromyalgia, tendonitis, and bursitis, carpal tunnel syndrome, TMJ, post-traumatic pain and inflammation, and heartburn. MSM also has benefits for allergy sufferers. According to Jacob, Lawrence and Zucker, “After many years of treating pain patients with MSM, it has become clear that perhaps a single most powerful benefit it offers is quick relief of the symptoms of common allergies. In hundreds of cases, this nutritional supplement has proved highly effective.”

The primary reason for MSM’s value is its high sulfur content. MSM contains 34 percent sulfur—the fourth most abundant mineral in the human body and one critical to making collagen, the primary constituent of cartilage and connective tissue. MSM is thought to deliver sulfur to the body in a usable way so it can be incorporated into these tissues. Many people using MSM as a dietary supplement have attested to its effectiveness.

“I was acquainted with an elderly woman who had been on Prednisone for severe arthritis for a number of years,” says Rob Benjamin, director of quality control for Bergstrom Nutrition in Vancouver, Washington. “Her doctor had to take her off of it because of what it was doing to her kidneys. Her knuckle joints were about an inch and a half thick. I gave her a sample of MSM, then ran into her about six days later. She came up, threw her arms around my neck and took her gloves off, and the thickness of her knuckles had reduced to almost normal. All the swelling was gone.”

The leading MSM product, manufactured to the most stringent product specifications available, is OptiMSM®, made by Bergstrom Nutrition. The crucial step that makes OptiMSM of such a high quality is its distillation process, in which heat is used to separate pure MSM from impurities and the by-products of manufacturing. The company has evolved the exact boiling points that allow MSM to be isolated, consistently producing the purest MSM available.

“Our methods are more expensive and more energy intensive,” Says Benjamin. “But our prime concern is delivering the purest product available.”

Peter Gilliham’s Natural Vitality is proud to include OptiMSM in its daily multi nutrient Organic Life Vitamins (OLV).

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Scientific Method of Evaluating the Effectiveness of Natural Medicines
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Date: April 21, 2007 01:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Scientific Method of Evaluating the Effectiveness of Natural Medicines

Author Dale Ericsson, M.D.; Shinian Cao, M.D.; Fred Crawford, Ph.D; Dale Haufrect, M.D. and Tommy E Hall, Jr.; USA

Introduction

It has been traditionally assumed that long chain mucopolysaccharide and other natural ingredients found in aloe vera are active only in aloe vera are active only in their unadorned and non-modified state. There is little scientific evidence, however, to support this conclusion. In fact, certain isolated components of aloe vera have pronounced specific pharmaco-therapeutic effects. The purpose of this series of experiments is to evaluate this unique method of scientifically evaluating biological and herbal products and to specifically compare fractionally distilled aloe preparation from a traditional ale preparation.

Conclusion

Utilizing the scientific method of white blood cell (T lymphocyte) culture, stimulation and metabolic turnover rates of more than 25 substances it was determined that:

1. the pivotal study had demonstrated that this type of T lymphocyte cell culture metabolic analysis is useful for evaluation the safety and efficacy of a variety of treatments in which there is only antidotal or clinical studies to support the therapeutic effect.

2. This technique of single blinded study has been employed to define the efficacy as well as compare fractionally distilled aloe vera (warren Aloe) and a traditional aloe vera product. Application of this type of blinded study to two different forms of aloe vera showed that the following conclusion may be expressed with certainty.

  • Fractionally distilled aloe (Warren Aloe) of Aloe vera breaks apart the long chains of mucopolysaccharides. These long chains prevent maximum effect.
  • These shorter chains are then more effective in statistically increasing activity of cell cultures in the following manner.
  • Fractionally distilled Aloe produces virtually the same cellular metabolic responses as found with natural Aloe juice.
  • Mitochondrial stimulation with increased fructose turnover appears greater in those patients while taking fractionally distilled aloe, while at the same time the insulin/glucose interaction is about the same with both aloe preparations.
  • There appears a decreased calcium, magnesium and zinc metabolic turnover in those patients on natural aloe juice.
  • Alpha lipoic acid turnover is decreased in patients taking natural aloe juice.

This data suggest that the fractionally distilled Aloe vera is bio-pharmaceutically active and provides specific changes in T cell cultures when compared to baseline and with natural aloe vera juice.

This information has been condensed. For entire report refer to EXPLORER! For the processional magazine; volume thirteen: number Two: Pages 15-19.

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EpiCore Benefits
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Date: April 09, 2007 05:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EpiCore Benefits

Benefits

EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in Cedar Rapids, Iowa called Diamond V Mills, Inc. began manufacturing and selling a fermentation product from the yeast Saccharomyces cerevisiae, the same yeast used in bread and beer making. The product was and still is used as an additive for animal feed to help improve digestion as well as overall health in animals. It has been on the market for over 60 years.

Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.

Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*

A comparison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4

NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2

High Metabolite Immunogen*: Nutrient Make-up

Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2

Beneficial Antioxidant Activity*

EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5

In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2

Safety

Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3

In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.

The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1

Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine samples were analyzed. No clinically relevant abnormal effects on the participants were found1.

 

EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.

 

EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*

Suggested Adult Use: Take one capsule daily with or without food.

 

 

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

Scientific References

1. Embria Health Sciences

2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.

3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the American College of Nutrition, 2006; 25(5): 465.

4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.

5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem 2004 Jun 16;52(12):4026-3



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N-acetylneuraminic acid
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Date: March 08, 2007 05:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: N-acetylneuraminic acid

Whey protein concentrate or isolate and chicken eggs

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Olive, With a Twist – The Leaves of the Olive Tree are as beneficial to our health as the
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Date: October 07, 2006 02:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Olive, With a Twist – The Leaves of the Olive Tree are as beneficial to our health as the

Olive, With a Twist – The Leaves of the Olive Tree are as beneficial to our health as the famous oil.

Okay class, its time for a beneficial botanicals pop quiz. Raise your hands—how many people here know that olive oil is good for you? The whole room not surprising. Now, how many know that olive leaf is also good for you? There are not quite so many hands up this time. Let the lesson begin.

The olive tree occupies a prominent place in ancient history and no wonder: olives and the oil hey contain were (and are) dietary staples in the Mediterranean world. (The Greeks were so enamored of the olive tree that they ascribed its creation to the goddess Athena.) But the leaf of this venerable tree has also made historical appearances, generally as a folk remedy for bringing down fevers. The mechanism behind that action didn’t come to light until scientists were able to isolate a substance called oleuropein, responsible for both the bitter taste of uncured olives and the tree’s hardy nature and resistance to bugs and bacteria.

Germ Buster

In the laboratory oleuropein extract has been as tough on many of the bacteria and viruses that plague human beings as it is on the olive tree’s natural enemies, a finding which helps explain why olive leaf has traditionally worked as well in fighting fevers (a sign of infection). Various types of rhinovirus (common cold), influenza and herpes virus have been numbered among oleuropein’s victims, along with the bacterial bad guys Escherichia coli (a strain of which can cause food poisoning) and staphylococcus aureus (the prime suspect in many hospital acquired infections).

Viruses are especially difficult to vanquish—antibiotics, as anyone suffering from the flu can tell you, don’t touch these tiny marauders. Olive leaf’s power lies in its ability to thwart viruses from replicating; now replication means no new viruses, which means no spread of infection. Olive extract can also incite immune system cells into gobbling up harmful micro-organisms.

Better Blood

In addition to thwarting microbes, olive leaf promotes better circulatory health. The white-coat crowd has discovered that oleuropein extract relaxes constricted arteries, which results in reduced blood pressure. And olive not only reduces blood sugar (glucose) levels but also serves as an antioxidant, a substance that can mop up harmful molecules known as free radicals. Given that oxidation plays a key role in the development of diabetic complications, both actions make olive leaf an intriguing option for people with diabetes. What’s more, oxidation also affects LDL cholesterol, turning it into the bad stuff that clogs arteries; olive leaf appears to interfere with this insidious process. This triple action-the ability to reduce blood pressure, glucose and LDL oxidation—may give olive leaf an important role in fighting metabolic syndrome, a cluster of health woes that helps fuel the worlds epidemic of cardiovascular disease.

The latest news from the olive grove: what boosts your blood may also benefit your bones. French researchers, intrigued by the low occurrence of osteoporosis among people who consume olive-heavy Mediterranean diets, found that female rats who received oleuropein showed less inflammation-induced bone loss than those fed standard rat chow (Clinical Nutrition 2006 online).

Surprised to learn that the olive trees leaf is just as valuable as its fruits? It’s true-and olive leaf deserves to go straight to the head of the class. --Lisa James.



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You can also find great brands like Solaray Vitamins and Now Vitamins at discount prices every day at VitaNet!

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The True Whey, boost your immune system
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Date: April 29, 2006 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The True Whey, boost your immune system

The True Whey™


Premium Protein Powder

The True Whey is a superior source of complete, biologically active, immunity-boosting protein. It is easy to mix and tastes great, a powerful addition to your daily health regimen. The True Whey is a non-denatured whey protein concentrate, produced to maintain the fragile, immune-boosting, and regenerative components naturally present in fresh milk. Highly digestible, whey has one of the highest biological values of any protein source. Traditionally, whey is formed from the liquids that separate from the milk solids in the cheese-making process. Often, the process involves high temperatures and acidic conditions that may denature the nutrients. The True Whey, however, is made from a unique, proprietary process that preserves the nutrients of the whey. In each 10 grams, you receive 8 grams of protein, 900 mg immunoglobulins, 190 mg lactoferrin, 40 mg calcium, 60 mg potassium, and 30 mg phosphorus. The True Whey provides whole protein, not protein isolates. Intact, biologically-active proteins support your immune system, regulate the use of minerals in the body, protect the digestive tract, and protect your body from oxidative stress. The typical American diet is glutted with refined sugars, carbohydrates, and fats which can have a significant impact on your health. To balance these influences and support normal weight, energy levels and overall health, each 10 grams of The True Whey contains 80% protein and only 38 calories, 6% total fat, 3% saturated fat, and 8% carbohydrates. The True Whey is made from milk from contented cows, which are grass fed and never subjected to any growth hormone treatment, chemicals, pesticides, or genetically modified organisms (GMO's).

Supplement Facts
Serving Size: 10 g (1 rounded scoop)
Serving per container 45

Amount %DV
Whey Protein Concentrate 10 g
Protein 8 g 15
Immunoglobulins* 900 mg
Lactoferrin* 190 mg
Calcium 40 mg 4
Calories 38
Calories from Fat 6
Total Fat 0.5 g <2
Saturated Fat 0 g <2
Cholesterol 15 mg 4
Sodium 20 mg 4
Total Carbohydrate 1 g <2
Dietary Fiber 0 g >2
Sugar 1 g <2
Potassium 60 mg
Phosphorus 30 mg
*Naturally occurring. Amounts may vary.

Other Ingredients:

Warning: If you are allergic to dairy products or are pregnant or breastfeeding, consult your health care professional before using this product. If you are taking prescription drugs, including antibiotics, consult your health care professional before using this product.

Suggested Use: Blend one scoop (10 grams) into your favorite cold beverage. Add ice and blend with fruit or yogurt for a delicious smoothie.

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Perplexed about Protein? immunoglobulins to boost the immune system.
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Date: April 29, 2006 01:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Perplexed about Protein? immunoglobulins to boost the immune system.

The Wellness Revolution

Perplexed about Protein?

As protein and whey powders have advanced in popularity, the confusion about them has grown. In particular, protein processing technology has advanced by leaps and bounds; consumers are being presented with protein claims and counter-claims that are highly contradictory.

The confusion is part of a rapid growth. Little Miss Muffet’s quiet dish of curds and whey has expanded from a minor sideline aid for weight lifters, with sales increases around to percent a year, into an explosive $1 billion a year industry, with some companies announcing sales growth of 110 percent in just the last year.

The increase in market is from whey’s expanding appeal. As new technology has made whey’s nutritive value beneficial to a wide range of consumers, more people are using whey, and whey is being added to more products. The problem is, those advanced nutritive qualities are not included in all whey products. The fantastic immune benefits, for example, apply to only the top tier of whey products.

Protein Quality

The standard of protein quality—the ability to provide indispensable amino acids—is judged on the basis of digestibility, nutrients, and amino acid composition. Whey has historically been acknowledged as on of the best sources of high quality protein.

With the increasing popularity of whey, attention on new processing methods has raised the bar on quality, and new products have greatly expanded nutritional values. What may have been an acceptable high-quality whey protein a few years ago, no longer makes the grade. Tony Lucchesi, Natural Sales Trainer at Source Naturals says, “The different processing methods have changed the entire protein market.”

He explains, “In separating casein from whey, (a process used to make cheese), most processing methods use heat, chemical modification, or pH adjustments. These all damage the native protein structure. The result is little or no biological activity in the whey product. All the low temperature drying and micro-filtration won’t help if the raw material is denatured before a protein is dried and brought to market.”

Damaged Proteins

Damaged protein may have been acceptable a few years ago, but it isn’t now. Lucchesi continues, “Animal experiments have shown that polypeptides—whole, non-denatured proteins—have greater nutritional value than protein isolates.”

Protein isolates are what is left after the pasteurization process. The protein has traditionally been “Cross cooked” out of its normal balance. “What you have left are incomplete bits and pieces of whole protein,” he says. These protein bits have only partial nutrients.

New Whey

The latest introduction to the protein category are concentrates, which are intact, biologically-active whole proteins. The entire difference is in the processing; high heat, acids, and traditional methods of separating the caseins from the whey are no longer used. The new processing preserves the nutrients of the protein. This is the method that is the basis for a new Source Naturals whey product, True Whey.

Lucchesi says, “TRUE WHEY is different in that it was designed to provide nutritional support for enhanced immune function. The entire process was designed for nutritive value. The preservation of these nutrients—lactoferrin, glutamine, immunoglobulins—give TRUE WHEY a huge benefit to athletes, children, and anyone interested in boosting their immune system.”

Per serving, TRUE WHEY offers 8 grams of un-denatured protein that includes 900 mg immunoglobulins and 190mg of lactoferrin. Its vanilla flavoring has gotten very high reviews, and it has a two-year shelf life. It appears that the bar has truly been raised in the whey protein category!

THE TRUE WHEY 16 oz. from SOURCE NATURALS

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Fighting fat with fat makes sense with conjugated linoleic acid.
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Date: April 03, 2006 04:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fighting fat with fat makes sense with conjugated linoleic acid.

Trimming flab away with CLA

Fighting fat with fat makes sense with conjugated linoleic acid.

Substances that enhance human health and well being can be discovered in all sorts of odd places. Take conjugated linoleic acid (CLA), for example. This unique fatty acid currently under intense study as an aid to help dieters reduce body fat—was first isolated from grilled ground beef in the early 1980’s by researchers at the University of Wisconsin. (CLA is also found in hamburger that ma actually help you slim down? Who knew?

What’s more, CLA (now generally derived from plant sources like safflower oil) also shows promise in two important areas. First, evidence suggests it can slow down some of the steps in cancer’s complex progression. In addition, CLA may help tame excess inflammation.

Fat City

When you take in more calories through food than you burn off through exercise, all those extra energy units have to go somewhere and if you’re like a lot of folks, they wind up being deposited into your fat cells. Not only are jam-packed fat cells responsible for the dreaded disappearing waistline effect, but they also promote unhealthy changes in blood pressure, cholesterol levels and other makers of possible hazards to your continued well-being.

CLA helps make life miserable for fat cells in several ways. First, it inhibits an enzyme called lipoprotein lipase that shuttles fat molecules from the blood stream into the cells. It encourages lipolysis, or the breakdown of fat that’s already in storage. Finally, in some studies CLA has shown an ability to actually encourage fat cells to commit a form of cellular suicide call apoptosis—which results in fewer places for fat to hide. At the same time, CLA promotes the transport of fat into exercising muscle cells, helping them to both burn off calories and become more toned (and shapely).

CLA Comments: What is it: a special form of linoleic acid, an essential fat: CLA is found naturally in diary foods.

What it does: CLA has shown an ability to help reduce body fat and increase muscle mass (When used as part of a healthy diet and exercise plan); it has also demonstrated cancer-fighting and immune enhancing effects.

While CLA is the subject of ongoing research, early human trials have produced promising results. In Norway, for example, scientists from five separate institutions teamed up for a study involving people who were healthy but over weight. For the first year some of the individuals took CLA while the others took placebo (look-alike) softgels that contained olive oil instead; in the second year, everyone took CLA. At the end of two years, all the people in this study showed significant reductions in body fat, body mass index (BMI), a standard measure of obesity, and weight(Journal of nutrition 4/05).

Extra Helpings

While battling the bulge is a major goal for many people, fending off cancer may just be America’s number one health concern. And here, too, CLA has come up big in a number of studies, such as a Swedish investigation that shows a link between high CLA intake and reduced colorectal cancer risk (American Journal of Clinical nutrition 10/05). In various lab studies CLA has been shown to interfere with tumor development and keep cancerous cells from spreading to nearby organs.

What’s more, CLA appears to regulate immunity by helping to strengthen the body’s natural defenses while protecting against the inflammatory damage the immune response can cause. That’s important because low-level inflammation has been linked to an ever-growing list of disorders, including cancer, cardiovascular disease and arthritis.

If you want to fight off both fat and cancer without eating a mountain of cheeseburgers, don’t have a cow. Turn to CLA instead.

--Lisa James.

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TriOxil the solution for your acne!
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Date: February 25, 2006 01:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: TriOxil the solution for your acne!

If you have tried other acne medications containing benzoyl peroxide, salicylic acid, and tretinoin that did not work for you then Trioxil® may be a solution for your acne – it is a totally new innovation and a remarkable breakthrough in acne treatment. Trioxil® (bisazulene gel) 14% is a modified form of naturally occurring compound found in chamomile flowers and encapsulated in nanosomes. The pharmacological activity of this compound has been shown in clinical studies to be antibacterial, antimicrobial, fungicidal and at the same time anti-inflammatory.

While other acne medications containing bezoyl peroxide, salicylic acid, or tretinoin have strong antimicrobial activity on Propionibacterium Acnes, these medications cause severe over-drying and irritation of the skin. This causes the body to respond by producing even more oil to combat dryness thereby starting a vicious never ending cycle. Trioxil® is the only acne medication that has antimicrobial activity against Propionibacterium Acnes bacteria while at the same time deeply calming and soothing the skin. In fact, the bisazulene compound (a very strong antimicrobial and antibacterial) is actually derived from from chamomile flowers which are well known for having soothing and calming properties. Thus Trioxil® treats both of the underlying causes - the bacteria involved in acne pathogenesis and the inflammatory response of acne.

The Trioxil® (bisazulene gel) 14% is delivered in a carrier agent that contains encapsulated extracts of compounds that further enhance the action of bisazulene and provide for better general skin health and appearance. The following compounds derived from the finest raw extracts have been added to the carrier agent gel:

Encapsulated extracts of Ginseng and Hamamelis: toning and astringent action that strengthens the tissues and regulates the secretion of oils.

Wheat-germ and Barley-germ Liposomes: nourishes and feeds the skin helping in the process of cell regeneration.

Arnica Liposomes: Arnica micro-capsules have deep reaching antiseptic action that helps to regulate oil secretion.

Trioxil® (bisazulene gel) 14% in a carrier agent of natural encapsulated extracts soaks immediately into the skin and acts for 12 hours. Trioxil® combats Propionibacterium Acnes bacteria and fungi, and controls the secretion of oil. Trioxil® has also been shown effective in closing the pores and eliminating dead cells, thereby encouraging new cell growth. It has a soothing, healing and anti-inflammatory action and most users can see an improvement in their acne within just 2 weeks of treatment.

While acne is not a threatening health condition it can have profound psychological consequences to those afflicted and can also leave permanent scars on the face and back if left untreated. Studies have shown that people affected with acne are generally more socially withdrawn, can become isolated, and miss important opportunities to develop social skills. Enter Trioxil® , a topical breakthrough acne treatment that can start clearing up skin in as little as two weeks.

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New Frontiers in Enzyme Supplementation
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Date: February 16, 2006 04:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: New Frontiers in Enzyme Supplementation

New Frontiers in Enzyme Supplementation

By Nick Rana, CN, NOW Quality Assurance

Serrazimes® is a proteolytic (protein digesting) enzyme system containing protease that is derived from edible non-genetically engineered fungi (Aspergillus oryzae and Aspergillus melleus), that is designed as an alternative for Serrapeptidase (also known as serratio-peptidase and serrapeptase) in dietary supplements used for cardiovascular, anti-inflammatory, respiratory, or immune support.

Serrapeptidase was initially isolated from Serratia marcescens, a potentially pathogenic bacteria found in the gut of the Japanese silkworm. Recognized as a pharmacological agent, Serrapeptidase has wide clinical use in Asia and Europe for the management of assorted inflammatory processes (Rothschild, 1991). In recent years, recognition of the efficacy of the Japanese product has lead to growing interest in the US dietary supplement market.

The product’s efficacy and availability over the internet has fueled its popularity in the US dietary supplement industry, where it is used for anti-inflammatory support, cardiovascular support, respiratory support, and as an adjunct to antibiotic therapy. Recognizing the potential for a "Serrapeptidase-type” enzyme in the U.S. dietary supplement market, the National Enzyme Company developed a protease system that has the same in vitro (lab test) activity as Serrapeptidase, but that is from organisms that have a long history of safe use in dietary supplements. Serrazimes® is the product resulting from this search.

Since the 1960’s, plant and microbial protease enzymes have been studied for their role in the management of inflammation and inflammatory processes. In both animal and human trials, proteolytic enzymes, from a variety of sources, have repeatedly been shown to significantly reduce inflammation resulting from sickness or injury (Ryan, 1967)(Smyth et al, 1967)(Shaw, 1969)(Kumakura et al, 1988)(Lomax, 1999). The earlier research on the anti-inflammatory actions of proteases pointed entirely to their antithrombic and fibrinolytic aspects to explain this phenomenon. However, studies by Parmely (Infect and Immun Sept 1990) and others indicate that, in addition to degrading fibrin, microbial proteases may actually inactivate pro-inflammatory cytokines and to interrupt inflammatory responses.

Persons taking blood thinning or antibiotic medications and those with serious health disorders should consult their medical practitioner prior to taking Serrazimes®. As is the case with most supplements, please consult your doctor about the use of Serrazimes® during pregnancy and lactation.

The Product Development Team at NOW Foods is constantly researching new products like Serrazimes® to provide our customers with the tools that empower them to live healthier lives. Look also for our new unique digestive enzyme formulations from plant sources - backed by laboratory studies - to be introduced in March of 2006.

TECHNICAL NOTES:

Serrapeptidase is a selective alkaline metalloprotease enzyme, meaning that it works to activate specific biological systems of mammals and directly degrades or inhibits IgG and IgA immune factors as well as the regulatory proteins á-2-macroglobulin, á-2-antiplasmin, and antithrombin III (Molla et al, 1989)(Maeda and Molla, 1989).

While originally isolated from Serratia marcescens, a bacteria found in the gut of the Japanese silk worm, Serrapeptidase activity is also found in fermentation extracts of Serratia E-15, Aspergillus oryzae, and Aspergillus melleus. (Salamone and Wodzinski, 1997).

The Serrapeptidase activity of this high potency proteolytic (protein digesting) enzyme is determined using a spectrophotometric assay testing procedure that measures the enzyme’s ability to hydrolyze (digest) a standard casein protein substrate. Laboratory analyses have established that Serrazimes® has a 1:1 enzymatic equivalent of Serrapeptidase activity guaranteed to provide 600,000 specialized proteolytic Units per gram, or 20,000 units per capsule.



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Benefits of L-Carnitine
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Date: February 12, 2006 03:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of L-Carnitine

Benefits

Helps the body burn fat for energy*

L-Carnitine promotes energy production in cells by transporting fatty acids into the mitochondrion. Its primary function is to transfer long-chain fatty acids across the inner mitochondrial membrane. Fatty acid molecules are activated to coenzyme A (CoA) esters in the cytoplasm of the cell, and then esterified to L-Carnitine. The combination of a fatty acid molecule and L-Carnitine is called “acyl-carnitine.” Much of the body's L-Carnitine content is stored in the form of acyl-carnitine.1

The mitochondrion is the cell’s energy-generating furnace. Called an “organelle,” the mitochondrion is a self-contained structure inside the cell. Like all cellular structures, the mitochondrion is surrounded by a membrane. This membrane is an impenetrable barrier to acyl-CoA esters; passage across the membrane requires L-Carnitine as a transporter. On the inside of the mitochondrial membrane, the acyl-CoA esters are made available to be metabolized through the process of beta oxidation. One of the key metabolic byproducts of this process is acetyl-CoA, also called “active acetate,” which enters the Krebs cycle (also known as the “citric acid cycle”) to supply fuel for production of ATP, the cell’s primary energy “currency.” L-Carnitine shuttles excess fatty acid residues out of the mitochondrion, and in this role is essential for preventing toxic buildup of fatty acids inside the mitochondrion.

Evidence suggests that L-Carnitine and short chain acyl-carnitine esters can protect the mitochondrion from adverse effects of drugs and toxic chemicals. L-Carnitine has been shown to protect animals form cardiotoxins and decrease mortality rate in animals with diphtheria, due to this cardioprotective effect.2

Helps maintain a healthy heart and cardiovascular system*

Muscle tissue contains a high concentration of L-Carnitine. With its constant energy needs, heart muscle tissue is especially rich in L-Carnitine. If the body’s ability to biosynthesize L-Carnitine is compromised, energy production in muscle tissue is impaired, and a toxic buildup of fatty acids can occur.3 Defective production of L-Carnitine by the body can result from a variety of factors, including kidney or liver malfunction, increased catabolism or the inability of tissues to extract and retain L-Carnitine from the blood.

Along with glucose and lactate, fatty acids are the primary oxidation fuel for the heart. A considerable amount of scientific data from animal experiments indicates that L-Carnitine protects the heart under conditions of hypoxia, or low oxygen. In addition to the oxidation of fat for energy in the cell, L-Carnitine is involved in the metabolism of glucose.4 Evidence of L-Carnitine’s role in glucose metabolism was uncovered in a small trial on 9 diabetic individuals. Given intravenously, L-Carnitine improved insulin-mediated glucose utilization and insulin sensitivity.5

Depletion of the body’s L-Carnitine supply is linked to various abnormal states, especially of the heart muscle. The effect of L-Carnitine on hypoxic (oxygen-starved) isolated heart muscle tissue has been studied.6 At high concentrations, L-Carnitine demonstrates a clear-cut ability to potentiate the contractility of isolated heart muscle tissue, indicating the L-Carnitine has a strengthening effect on the heart. L-Carnitine has been shown to improve the performance of rats subjected to fatigue test.

Research has revealed that in animals and humans with defective heart muscle, the amount of free L-Carnitine (not bound to fatty acids) is reduced. Administration of L-Carnitine to hamsters prevents damage to the heart muscle. Given to humans with angina, L-Carnitine was found to improve exercise tolerance. In a small study, patients with congestive heart failure showed gains in heart function with oral consumption of L-Carnitine, reportedly by restoring normal oxidation of fatty acids.7 In heart valve replacement patients, L-Carnitine has been shown to increase the valve tissue levels of ATP, pyruvate and creatine phosphate, which are key cellular energy substrates. In a controlled study, L-Carnitine was administered to 38 patients prior to open heart surgery. Prior to surgery, heart circulatory function, as assessed by measurements of hemodynamics, was “good” in all 38. While there was evidence of a “preserving” effect of L-Carnitine on heart cells, no differences in cardiac performance were observed. These results suggest that noticeable improvements in heart muscle performance with L-Carnitine are most likely to occur in people with compromised hearts.8

It has been suggested that L-Carnitine favorably influences blood lipids. Preliminary evidence of this was seen in a small open trial on 26 patients who took 3 grams of L-Carnitine daily for 40 days. Blood levels of cholesterol and triglycerides dropped substantially, while the ratio of total to HDL cholesterol–– a known marker of cardiovascular health––markedly improved.9

While L-Carnitine is not a treatment for heart disease, (nor should it be used as a substitute for medical treatment) the results of these and other studies suggest that oral consumption of L-Carnitine has a beneficial influence on maintaining a healthy heart and cardiovascular system.



Safety

Suggested Adult Use: Take 1 to 4 capsules daily without food.

L-Carnitine is considered to be very safe for oral consumption. L-Carnitine is generally well tolerated, even at doses as high as 15 grams daily. Toxicity or overdosage has not been reported.10



Scientific References
1. Wagenmakers, A. L-Carnitine supplementation and performance in man. Brouns, F. ed. Advances in Nutrition and Top Sport. Med Sport Sci. Basel, Karger, 1991;32:110-27.
2. Arrigoni-Martelli, E., Caso, V. Carnitine protects mitochondria and removes toxic acyls from xenobiotics. Drugs Exptl. Clin. Res. 2001;27(1):27-49)
3. Pepine, C.J. The therapeutic potential of carnitine in cardiovascular disorders. Clinical Therapeutics 1991;13(1):2-21.
4. Calvani, M., Reda, E., Arrigoni-Martelli, E. Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. Basic Research in Cardiology 2000;95(2):75-83.
5. Capaldo, B. et al. Carnitine improves peripheral glucose disposal in non-insulin-dependent diabetic patients. Diabetes Research and Clinical Practice 1991;14:191-96.
6. Fanelli, O. Carnitine and acetyl-carnitine, natural substances endowed with interesting pharmacological properties. Life Sciences 1978;23:2563-2570.
7. Kobayashi, A., Masumura, Y., Yamazaki, N. L-Carnitine treatment for congestive heart failure-experimental and clinical study. Japanese Circulation Journal 1992;56:86-94.
8. Pastoris, O. et al. Effect of L-Carnitine on myocardial metabolism: results of a balanced, placebo-controlled, double-blind study in patients undergoing heart surgery. Pharmacological Research 1998;37(2):115-22.
9. Pola, P. et al. Carnitine in the therapy of dyslipidemic patients. Current Therapeutic Research 1980;27(2):208-16.
10. L-Carnitine. PDR for Nutritional Supplements. First Ed. 2001.Montvale, NJ:Medical Economics.



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Benefits of Acetyl-L-Carnitine
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Date: February 12, 2006 01:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Acetyl-L-Carnitine

Benefits

Supports cognitive function*

ALC has been studied for its effect on cognitive performance and emotional health in the elderly. In a single-blind, placebo-controlled trial, 481 elderly subjects exhibiting mild memory impairment improved their scores on a memory test after taking 1500 mg of ALC a day for 90 days.2 Hospitalized elderly people taking ALC have shown improvements in mental outlook.3 While ALC is not a treatment or cure for Alzheimer's disease, double-blind studies suggest it may help slow the rate at which early-stage Alzheimer's patients deteriorate.4 In particular, ALC seems to benefit short-term memory in these patients.5

Supports biosynthesis of acetylcholine, a key neurotransmitter for brain and nerve function* Brain function requires coordinated communication between brain cells. Brain and nerve cells ("neurons") communicate across tiny cell-to-cell gaps called "synapses." The passage of an electrical impulse from one neuron to the next requires a "neurotransmitter." When an electrical signal arrives at the synaptic junction, the neuron releases a neurotransmitter into the synapse. The neuron on the other side of the synapse contains receptors for the neurotransmitter; these receptors bind the neurotransmitter, triggering a series of chemical events that sends a new electrical signal down the membrane of the receiving neuron. Neurotransmitters work together like an orchestra to transmit information throughout the brain and nervous system. Acetylcholine is the most abundant neurotransmitter in the body, regulating activities of vital organs, blood vessels and communication between nerves and muscles. In the brain, acetylcholine helps facilitate memory and learning as well as influence emotions. ALC is structurally similar to acetylcholine, and brain neurons stimulated by acetylcholine are receptive to stimulation by ALC.6 It has been shown experimentally that ALC supplies acetyl groups for the biosynthesis of acetylcholine.7 ALC's hypothesized cholinomimetic (acts like acetylcholine) activity has led researchers to investigate its effects on mental function and emotional health.8

Helps supply the brain with energy by improving energetics in the mitochondrion*

The acetyl groups donated by ALC can be used to synthesize acetyl-CoA, the key substrate for energy metabolism in the mitochondrion. 9 Acetyl-CoA enters the Krebs cycle, the mitochondrial mechanism that generates cellular energy in the form of ATP. ALC easily crosses the blood-brain barrier, allowing it to play various roles in maintaining brain neuron (nerve cell) function. When given by oral administration, the concentration of ALC is increased in the blood and cerebrospinal fluid.10

Stabilizes intracellular membranes*

ALC was found to improve membrane phospholipid metabolism in early-stage Alzheimer's patients.11 Phospholipids are structural components of brain cell membranes that regulate neuron function. ALC donates acetyl groups that can be used to modify the functional activity of proteins in neuronal membranes.12 ALC thus plays a role in maintaining membrane function. ALC also increases membrane stability and structural integrity.13

Increases nerve growth factor production*

The body produces various specialized proteins called "growth factors" which are essential to growth and repair of tissue. Nerve Growth Factor (NGF) protects neurons from death, prolonging survival of neurons in both the central and peripheral nervous systems. It is theorized that aging of the central nervous system is associated with a loss of NGF. ALC has shown the ability to reverse age-related decrease in the binding of NGF to its receptors in neuron membranes.14 Given to aged rats, ALC increases the level and utilization of NGF in the rats. ALC protects cholinergic neurons (nerve cells stimulated by acetylcholine) in rats from degeneration due to lack of NGF.15 These results, together with other data from animal studies, suggest that ALC positively influences NGF activity.16

Has a protective influence on brain neurons*

Several animal studies have revealed that ALC exerts a protective effect on neurons. In one experiment, brain cells from rats exposed to NMDA, a known neurotoxin, were protected by being simultaneously exposed to ALC.17 Rats injected with ALC were protected from mortality caused by the neurotoxin MPP+.18 ALC has been shown to raise levels of glutathione, a highly valuable antioxidant, in isolated mouse brain tissue.19 ALC prevents buildup of malondyhaldeyde, a marker of lipid peroxidation.20 ALC is also a chelator of iron, which can generate free radicals. It also reinforces antioxidant mechanisms in the brain.21 As a whole, data from test tube and animal studies, showing that ALC has a protective, restorative effect on brain neurons and neuronal energetic processes, suggest that ALC is an anti-aging nutrient for the brain. This hypothesis is supported by human studies demonstrating measurable benefits for brain function in elderly persons taking ALC by oral consumption.


Safety
Suggested Adult Use: 1 to 4 capsules daily.
ALC is considered safe and well-tolerated when consumed orally. ALC has been administered in doses as high as 3 grams per day for periods of two to six months, with no reports of serious side effects. Some patients have experienced occasional mild abdominal discomfort, nausea, skin rash, restlessness, vertigo and headache. The severity and incidence of these side effects are reported as minor.22

Scientific References
1. Pettegrew, JW, Levine, J, McClure, RJ. Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Molecular Psychiatry 2000;5:616-32.
2. Salvioli, G. Neri , M. L-acetylcarnitine treatment of mental decline in the elderly. Drugs Exptl. Clin. Res. 1994; 20(4):169-76.
3. Tempesta, E, et al. L-acetylcarnitine in depressed elderly subjects. A cross-over study vs. placebo. Drugs Exptl. Clin. Res. 1987;8(7):417-23.
4. Spagnoli, A et al. Long-term acetyl-L-carnitine treatment in Alzheimer's disease. Neurology 1991;41:1726-32.
5. Rai, G et al. Double-blind, placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's dementia. Curr. Med Res. Opin. 1990;11:638-47.
6. Falchetto, S, Kato, G, Provini, L. The action of carnitines on cortical neurons. Can J Physiol Pharmacol 1971; 49(1):1:7.
7. Dolezal, V., Tucek, S. Utilization of citrate, acetylcarnitine, acetate, pyruvate and glucose for the synthesis of acetylcholine in rat brain slices. J Neurochem 1981;36(4):1323.30.
8. Passeri, M, et al. Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine. Int. J. Clin. Pharm. Res. 1988;8(5):367-76.
9. Pettegrew, JW, Levine, J, McClure, RJ. Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Molecular Psychiatry 2000;5:616-32.
10. Parnetti, L, et al. Pharmacokinetics of IV and oral acetyl-L-carnitine in multiple dose regimen in patients with senile dementia of Alzheimer type. Eur. J. Clin Pharmacol 1992;42:89-93.
11. Pettegrew, JW, et al. Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease. Neurobiology of Aging 1995;16(1):1-4.
12. Pettegrew, JW, Levine, J, McClure, RJ. Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Molecular Psychiatry 2000;5:616-32.
13. Arduni, A, et al. Effect of L-carnitine and acetyl-L-carnitine on the human erythrocyte membrane stability and deformability. Life Sci 1990;47(26):2395-2400.
14. Taglialatela, G, et al. Stimulation of nerve growth factor receptors in PC12 by acetyl-L-carnitine. Biochem Pharmacol 1992;44(3):577-85.
15. Taglialatela, G, et al. Acetyl-L-carnitine treatment increases nerve growth factor levels and choline acetyltransferase activity in the central nervous system of aged rats. Exp Gerontol 1994;29(1):55-56.
16. Pettegrew, JW, Levine, J, McClure, RJ. Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Molecular Psychiatry 2000;5:616-32.
17. Forloni, G, Angeretti, N, Smiroldo, S. Neuroprotective activity of acetyl-L-carnitine: studies in vitro. J Neurosci Res 1994;37(1):92-6.
18. Steffen, V, et al. Effect of intraventricular injection of 1-methyl-4-phenylpyridinium: protection by acetyl-L-carnitine. Hum Exp Toxicol 1995;14(11):865-71.
19. Fariello, RG, et al. Systemic acetyl-L-carnitine elevates nigral levels of glutathione and GABA. Life Sci 1988;43(3):289-92.
20. Calvani, M, et al. Action of acetyl-L-carnitine in neurodegeneration and Alzheimer's disease. Ann Ny Acad Sci 1992;663:483-86.
21. Calvani, M, Carta, A. Clues to the mechanism of action of acetyl-L-carnitine in the central nervous system. Dementia 1991;2:1-6.
22. Zdanowicz, M. Acetyl-L-carnitine's healing potential. Continuing Education Module. New Hope Institute of Retailing. October, 2001.


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Scientific References
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Date: February 11, 2006 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Scientific References

Scientific References 1. Toyoda-Ono Y, Maeda M, Nakao M, Yoshimura M, Sugiura-Tomimori N, Fukami H. 2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit. J Agric Food Chem. 2004 Apr 7;52(7):2092-6.

2. Breithaupt DE, Weller P, Wolters M, Hahn A. Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. Br J Nutr. 2004 May;91(5):707-13.

3. Cheng CY, Chung WY, Szeto YT, Benzie IF. Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial. Br J Nutr. 2005 Jan;93(1):123-30.

4. Wu SJ, Ng LT, Lin CC. Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res. 2004 Dec;18(12):1008-12.

5. Zhao H, Alexeev A, Chang E, Greenburg G, Bojanowski K. Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts. Phytomedicine. 2005 Jan;12(1-2):131-7.

6. Gan L, Zhang SH, Liu Q, Xu HB. A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. Eur J Pharmacol. 2003 Jun 27;471(3):217-22.

7. Gan L, Hua Zhang S, Liang Yang X, Bi Xu H. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int Immunopharmacol. 2004 Apr;4(4):563-9.



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Essential Oil FAQ's - What are essential oils?
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Date: January 13, 2006 05:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Essential Oil FAQ's - What are essential oils?

Essential Oil FAQ's

What are essential oils?

Essential Oils are the naturally occurring volatile oils obtained by distillation or expression having the characteristic aroma of the plant part from which it was derived. These 100% pure oils are neat, meaning they have not been processed or manipulated in any way with solvents or other additives. Though a particular species of plant harvested and distilled for its essential oil during a particular growing season in a specific region may produce a fragrance that differs from the same species grown that season in a different region, many of the main chemical markers and physical specifications may be similar.

Do essential oils have a grading system to tell me which is better?

There are many companies selling Essential Oils today spinning many tall tales regarding the quality or grade of their products. To my knowledge there exists NO official grading system in any of the more respected sources of essential oil literature. Neither The Federal Register and Code of Regulations, FEMA nor AFNOR has to date adopted a system that grades these oils as an A, B or C grade. A product is either 100% pure essential oil or it’s not. All of our 100% pure essential Oils are labeled as such. We also sell oil blends that are formulated with essential oils or absolute extracts and pure grapeseed oil and are clearly labeled. Are NOW essential oils pure or do they have anything added to them?

Again all of our 100% pure essential Oils are labeled as such. We also sell oil blends that are formulated with essential oils or absolute extracts and pure grapeseed oil and are clearly labeled.

Natural Essential Oils by their very definition will vary from season to season. We are committed to allowing nature take its course without adding isolated compounds to the oil in an effort to improve on the naturally occurring nuance. We take both the organoleptic (sight, smell and taste) and chemical properties into account when evaluating our essential oils. What are NOW’s criteria for testing essential oils? Our Quality Assurance and Control departments adhere to specifications used by the Essential Oils and Flavor Industry and published in The Essential Oils by Guenther, as well as Fenaroli’s Handbook of Flavor Ingredients.

These texts, as well as other sources of scientific information, detail specific physical and chemical properties that compose a fingerprint defining the peculiarities of a particular oil. A partial list of the components that we analyze for would include Specific Gravity, Refractive Index, Optical Rotation, Flash Point, Infrared Absorption (as published in FCC), Solubility, Taste/Odor, Color/Appearance, Heavy Metals and Predominant Active Chemical Components. Our in-house laboratory employs state-of-the-art analytical equipment that allows us to perform highly specialized analyses, such as Gas Chromatography and Infrared Spectrometry. We use our own analysis results to confirm specification sheet results and certificates of analyses received from 3rd party outside laboratories and vendors. As always, when it comes to Essential Oils, individual practitioners and lay people will decide for themselves which variety of a flower or leaf produces the essential oil that best suits their particular need. The nose, eyes, ears, hands and heart of a man or woman, used with humility and wisdom, are still the best tools given us by God to discern what is necessary and good. NOW Foods is committed to offering the purest and most potent natural Essential Oils available. All of our 100% Pure Essential Oils are FCC or food grade and derived through natural distillation or cold pressing methods with no chemicals or solvents. NR 9/03

My family and I have been using Cassia essential oil topically on our feet. Is this OK since your bottle says “Not for Topical use”?

Skin irritation is possible with many oils, including the powerful Quassia or Cinnamon essential oils. Though many people do use our oils in a variety of ways, due to the powerful nature of steam distilled pure essential oils, we label these products with cautions and suggest that you consult an aromatherapist or health professional for proper use. These 100% pure oils are of the highest quality, undiluted and unadulterated. They are appropriate for any use where these concentrated oils are indicated, either as aromatherapy or with significant dilution.

Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.



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Gr-8 Dophilus
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Date: December 29, 2005 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gr-8 Dophilus

Did you know that poor digestive function is a contributing factor in more than ninety percent of America’s serious health issues?! The waiting rooms of doctors are jam packed, in part because so many people are suffering with gastrointestinal problems. The medical establishment and alternative health and wellness practitioners don’t always agree, but both sides are certain that a healthy digestive system is the cornerstone of good health. Proteins, the building blocks of life; carbohydrates and fats, your body’s source of energy; vitamins and minerals; and water – all are assimilated through digestion. If you’re not properly digesting the foods you eat, your body isn’t obtaining the nutrients it needs to repair, renew and thrive. Without the raw materials it needs to repair the damage we do to ourselves every day, your body begins to break down, leading to poor health and accelerated aging2,3.

While there are a multitude of factors involved in healthy digestive function, one of the most important is the delicate balance of bacteria found in the human gastrointestinal (GI) tract. There are three main types of flora in the human GI tract - Bifidobacteria, Bacteroides and Eubacterium. Of slightly less importance are Lactobacilli, Streptococci and Peptococci and other transitory flora1. Our stomachs and intestines are populated by hundreds of billions of these bacteria, or microflora. Amazingly, there are more probiotic organisms in our gut than there are cells in our bodies! That’s a lot of bacteria, but it’s GOOD bacteria, and each strain has specific functions in the human body. These bacteria aid the digestion of food and have protective qualities that contribute to good colon health. While a good balance of these different microflora is necessary, there are many factors that can, and do, disrupt this balance –certain medications, a poor diet, infection, stress, bad bacteria, aging and even the climate. The good news is a rapidly expanding body of research suggests that supplementing the diet with the right mix of microflora can have a beneficial affect on gastrointestinal function, and therefore overall health.

NOW® Gr8-Dophilus™ exclusively utilizes the finest strains from Rhodia Incorporated, the world’s leading supplier of high quality probiotic ingredients, and is enteric-coated to ensure that the bacteria in this product are not destroyed in stomach acid but reach the small and large intestines where they are most beneficial. Gr8-Dophilus is a vegetarian product that contains virtually no lactose.

Lactobacillus acidophilus is a well-studied microflora species that’s highly resistant to gastric acidity and is able to proliferate in the presence of bile. Like many probiotic organisms, it also adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.

Lactobacillus casei is a microflora strain that is found in the human mouth and intestines as well as in fermented vegetables, milk and meat. Recent research has shown that this bacterium is active in the GI tract and may help to modulate the immune system*. Research is continuing into this very promising probiotic.

Lactobacillus rhamnosus, like Lactobacillus acidophilus, is highly resistant to gastric acidity and proliferates well in bile. It, too, adheres well to intestinal cells. We’ve included this particular strain because it works extremely well with L. acidophilus. Lactobacillus salivarius is a strain that has proven highly effective against Helicobacter pylori, a bacterial species implicated in a number of digestive conditions. Studies have shown that L. salivarius is capable of producing high amounts of lactic acid, which has been shown to inhibit H. pylori growth in live subjects. Compared to other Lactobacillus strains, L. salivarius was proven to have the greatest inhibitory effect on the proliferation of H. pylori,4 which is why this strain is included in Gr8-Dophilus™.

Streptococcus thermophilus bacterium are isolated from yogurt and are recommended for lactose intolerant individuals to help digest lactose in the intestines. This strain is included in this formula to assist in the acidification of the intestinal environment, as well as to create a favorable environment for lactic acid bacteria.

Bifidobacterium bifidum is one of the workhorses of the large intestine. It has a high tolerance to gastric acidity, and, like L. acidophilus and many other probiotic organisms, it adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.

Bifidobacterium longum is a bifidobacterium of human origin that, like lactobacillus, is extremely resistant to gastric acid and bile salts. Because it’s anaerobic (able to live without oxygen) it’s perfectly suited to colonize the colon. Initial studies have shown that this particular strain of bifidobacteria helps to support the immune system*. It also seems to decrease enzymatic activity in feces. Researchers believe enzymatic activity in feces may contribute to carcinogenesis.

Bifidobacterium lactis is one of the most well-studied strains of probiotic bacteria, with a wealth of peer-reviewed, published research on its benefits. Clinical trials on B. lactis have shown it to be helpful in a number of digestive conditions, including diarrhea and lactose intolerance, as well as immune response modulation.

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Vitamin C FAQ's
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Date: December 27, 2005 05:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C FAQ's

Vitamin C FAQ's

What is Calcium Ascorbate?

Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.

What does Calcium Ascorbate do?

Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.

Is this a necessary vitamin or can our bodies make enough to satisfy our needs?

Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.

What is the function of the Citrus Bioflavonoids?

Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.

Why are there color variations in your different Vitamin C products, and are they safe to take?

Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.

Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.

Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.

NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.

Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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Glucosamine & Chondroitin - JOINT HEALTH
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Date: December 22, 2005 09:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine & Chondroitin - JOINT HEALTH

  • Supports Healthy Joint Structure and Function
  • Supports Mobility and Ease of Movement

References:
1) Balch, James F. et. al. ; Prescription For Nutritional Healing 3 rd rd rdPrescription Edition Edition ; Avery; Penguin Putnam; 2000
2) Benedikt, H.; Glycosaminoglycans And Derivatives For Treatment Of Arthritis; Chiropractic Products, May 1997, pp. 92-95
3) Reginster, Jean Yves et. al.; Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial; The Lancet, 2001, Vol. 357, No. 9252 4) Bassleer, C. et. al.; Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro; Osteoarthritis and Cartilage, 1998, 6, 427-434
5) Drovanti, A. et. al.; Therapeutic Activity of Oral Glucosamine Sulfate in Osteoarthritis: A Placebo-Controlled, Double-Blind Investigation; Clinical Therapeutics, Vol. 3, No. 4, 1980, pp. 260-272
6) Morreale, P. et. al.; Comparison of the Antiinfl ammatory Effi cacy of Chondroitin Sulfate and Diclofenac Sodium in Patients with Knee Osteoarthritis; Journal of Rheumatology, 1996, 23:8, pp. 1385- 1391



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SAMe (S-Adenosylmethionine)
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Date: December 17, 2005 09:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SAMe (S-Adenosylmethionine)

Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood

As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body.

There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable.

Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel.

SAMe (S-Adenosylmethionine)

SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.*

SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance.

As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants.

Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health.

SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification.

SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a stabilized form.

SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability.

This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed



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Nattokinase Fact Sheet
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Date: December 08, 2005 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nattokinase Fact Sheet

Nattokinase Fact Sheet

Neil E. Levin, CCN, DANLA 8/8/05

LIKELY USERS: People seeking to support heart health and healthy circulation.1-6

KEY INGREDIENTS: Nattokinase, an enzyme

STRUCTURE/FUNCTION USE: Nattokinase is an enzyme isolated from Natto, a traditional Japanese fermented soy food. Natto has been consumed safely for thousands of years for its numerous health benefits. More recently, both clinical and non-clinical studies have demonstrated that Nattokinase supports heart health and promotes healthy circulation. Each serving of NOWR Nattokinase provides 2,000 FU (Fibrinolytic Units) to help keep already healthy levels of blood clotting factors within a normal range. 1-6

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: An assay of 2,000 FU (Fibrinolytic Units) is equivalent to 160 IU on the Urokinase assay. The FU assay measures Nattokinase activity by using the fibrin plate method and measuring the absorption of released low-molecular weight substances.7 NOW Nattokinase is made from non-GE (non-genetically engineered) bacteria (Bacillus subtilis var. Natto) grown on non-GE soybeans and standardized on a base of non-GE, corn-derived maltodextrin.

SERVING SIZE & HOW TO TAKE IT: Take one vegetarian Vcap once or twice a day between meals (without protein).

COMPLEMENTARY PRODUCTS: Vein SupremeTM, Tru-E Bio ComplexTM, Pycnogenol®, garlic, and cayenne

CAUTIONS: None.

SPECIFIC: People with blood coagulation disorders or who take anticoagulant (“blood thinning”) medications (including aspirin) should consult a physician before use. Do not take if prone to bleeding. Unlike some other brands, NOWR Nattokinase contains no Vitamin K (K1 or K2), which would enhance clotting.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S (1995) Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull 18(10):1387-1391
2. Sumi H, Hamada H, Nakanishi K, Hiratani H (1990) Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol 84(3):139-143.
3. Suzuki Y, Kondo K, Ichise H, Tsukamoto Y, Urano T, Umemura K (2003) Dietary Supplementation With Fermented Soybeans Suppresses Intimal Thickening. Nutrition 19:261-264.
4. Suzuki Y, Kondo K, Matsumoto Y, Zhao B-Q, Otsuguro K, Maeda T, Tsukamoto Y, Urano T, Umemura K (2003) Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci 73:1289-1298.
5. Ito H, Suzuki T (2002) Effect of oral administration of nattokinase extract on blood mobility. Society of Analytical Bio-Sciences 25(4):1-5.
6. An Open Clinical Pilot Study to Evaluate the Safety and Efficacy of Natural Super Kinase as an Add-On Oral Fibrinolytic Agent to Low Molecular Weight Heparin and Anti-Platelets in Acute Ischaemic Stroke. (no authors listed) (2004)
7. Method: J of Agri Food Chem, Vol 48 (2000) P3, 210-213, 216



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CLA Extreme Fact Sheet
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Date: December 07, 2005 12:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CLA Extreme Fact Sheet

CLA Extreme Fact Sheet Neil E. Levin, CCN, DANLA 01/31/05

LIKELY USERS: People wanting to control body fat; People wanting to increase their body’s lean mass (muscle tissue); People wanting an oil that helps to reduce pro-inflammatory body chemicals; Those wanting to prevent undesirable cellular changes through diet KEY INGREDIENT (S): CLA from safflower oil, L-Carnitine amino acid, Guarana Seed extract (20% naturally occurring caffeine), Green Tea extract (40% polyphenols), Chromium Picolinate

MAIN PRODUCT FEATURES: Conjugated Linoleic Acid (CLA) is a derivative of linoleic acid, an essential fatty acid. The softgel is formulated with CLA (derived from safflower oil), Green Tea extract (polyphenols), Guarana extract (caffeine), L-Carnitine, and Chromium (III) Picolinate for synergistic effects of reducing body fat and increasing lean muscle mass.

OTHER IMPORTANT ISSUES: One study, titled "Efficacy and Safety of One-Year Supplementation with Conjugated linoleic Acid in Moderate Overweight," found that compared to placebo, CLA-supplemented subjects had Body Fat Mass index scores averaging 9% lower than the placebo group and had Lean Body Mass results showing lean muscle mass averaging 2% more than the placebo group. Analyses of blood tests showed no side effects over this one-year period. CLA plus Guarana reportedly reduces the size and number of fat cells in another report. CLA may also reduce insulin resistance and prevent undesirable cellular changes.

AMOUNT and HOW TO USE: One to five capsules a day, preferably with meals.

COMPLEMENTARY PRODUCTS: Alpha Lipoic Acid, Vitamin E, other Antioxidants

CAUTIONS: CLA may reduce insulin resistance, so people on blood sugar medications may not need as much of their drugs. Use with caution to avoid an overdose of your blood sugar medication when using this oil. Please notify your physician about your supplement use if you are using any drugs!

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Gaullier JM, Halse J, Hoye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen O. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am. J. Clin. Nutr. 79(6):1118–1125 (2004).

Tricon S, Burdge GC, Kew S, Banerjee T, Russell JJ, Grimble RF, Williams CM, Calder PC, Yaqoob P. Effects of cis-9,trans-11 and trans-1 0,cis-12 conjugated linoleic acid on immune cell function in healthy humans. Am. J. Clin. Nutr. 80(6):1626–1633 (2004).

Aminot-Gilchrist DV, Anderson HDI. Insulin resistance-associated cardiovascular disease: potential benefits of conjugated linoleic acid. Am. J. Clin. Nutr. 79(6):1159S–1163S Suppl. S (2004).

Bassaganya-Riera J, Reynolds K, Martino-Catt S, Cui YZ, Hennighausen L, Gonzalez F, Rohrer J, Benninghoff AU, Hontecillas R. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroenterology 127(3):777–791 (2004).

Bergamo P, Luongo D, Rossi M. Conjugated linoleic acid - Mediated apoptosis in Jurkat T cells involves the production of reactive oxygen species. Cell Physiol. Biochem. 14(1–2):57–64 (2004).

Bouthegourd JC, Martin JC, Gripois D, Roseau S, Tome D, Even PC. Fat-depleted CLA-treated mice enter torpor after a short period of fasting. Appetite 42(1):91–98 (2004).

Brown JM, Boysen MS, Chung S, Fabiyi O, Morrison RF, Mandrup S, McIntosh MK. Conjugated linoleic acid induces human adipocyte delipidation - Autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. J. Biol. Chem. 279(25):26735–26747 (2004).

Cheng WL, Lii CK, Chen HW, Lin TH, Liu KL. Contribution of conjugated linoleic acid to the suppression of inflammatory responses through the regulation of the NF-kappa B pathway. J. Agric. Food Chem. 52(1):71–78 (2004).

Choi JS, Jung MH, Park HS, Song JY. Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat-fed rats. Nutrition 20(11–12):1008–1017 (2004).

Cortes HN. CLA and body composition: Research shows conjugated linoleic acid can help maintain a healthy balance between lean muscle and body fat. Agro Food Industry Hi Tech 15(2):49–51 (2004).

Dauchy RT, Dauchy EM, Sauer LA, Blask DE, Davidson LK, Krause JA, Lynch DT. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. Cancer Lett. 209(1):7–15 (2004).

Eyjolfson V, Spriet LL, Dyck DJ. Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans. Med. Sci. Sport Exercise 36(5):814–820 (2004).

Field CJ, Schley PD. Evidence for potential mechanisms for the effect of conjugated linoleic acid on tumor metabolism and immune function: lessons from n-3 fatty acids. Am. J. Clin. Nutr. 79(6):1190S-1198S Suppl. S (2004).

Hirao A, Yamasaki M, Chujo H, Koyanagi N, Kanouchi H, Yasuda S, Matsuo A, Nishida E, Rikimaru T, Tsujita E, Shimada M, Maehara Y, Tachibana H, Yamada K. Effect of dietary conjugated linoleic acid on liver regeneration after a partial hepatectomy in rats. J. Nutr. Sci. Vitaminol. 50(1):9–12 (2004).

Inoue N, Nagao K, Hirata J, Wang YM, Yanagita T. Conjugated linoleic acid prevents the development of essential hypertension in spontaneously hypertensive rats. Biochem. Biophys. Res. Commun. 323(2):679–684 (2004).

Kritchevsky D, Tepper SA, Wright S, Czarnecki SK, Wilson TA, Nicolosi RJ. Conjugated linoleic acid isomer effects in atherosclerosis: Growth and regression of lesions. Lipids 39(7):611–616 (2004).

Lamarche B, Desroches S. Metabolic syndrome and effects of conjugated linoleic acid in obesity and lipoprotein disorders: the Quebec experience. Am. J. Clin. Nutr. 79(6):1149S–1152S Suppl. S (2004).

Malpuech-Brugere C, Verboeket-van de Venne WPHG, Mensink RP, Arnal MA, Morio B, Brandolini M, Saebo A, Lassel TS, Chardigny JM, Sebedio JL, Beaufrere B. Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans. Obesity Res. 12(4):591–598 (2004).

McCann SE, Ip C, Ip MM, McGuire MK, Muti P, Edge SB, Trevisan M, Freudenheim JL. Dietary intake of conjugated linoleic acids and risk of premenopausal and postmenopausal breast cancer, Western New York Exposures and Breast Cancer Study (WEB study). Cancer Epidemiol. Biomarkers Prevent. 13(9):1480–1484 (2004).

Moloney F, Yeow TP, Mullen A, Nolan JJ, Roche HM. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am. J. Clin. Nutr. 80(4):887–895 (2004).

Ochoa JJ, Farquharson AJ, Grant I, Moffat LE, Heys SD, Wahle KWJ. Conjugated linoleic acids (CLAs) decrease prostate cancer cell proliferation: different molecular mechanisms for cis-9, trans-11 and trans-10, cis-12 isomers. Carcinogenesis 25(7):1185–1191 (2004).

O'Shea M. Clarinol(TM) CLA (Conjugated Linoleic Acid): the weight of evidence supports a safe and efficacious product for weight management. Agro Food Industry Hi-Tech 15(4):24–26 (2004).

O'Shea M, Bassaganya-Riera J, Mohede ICM, Immunomodulatory properties of conjugated linoleic acid. Am. J. Clin. Nutr. 79(6):1199S–1206S Suppl. S (2004).

Rainer L, Heiss CJ. Conjugated linoleic acid: Health implications and effects on body composition. J. Am. Dietetic Assoc. 104(6):963–968 (2004).



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GliSODin® (The Antioxidant Catalyst) 100 mg Fact Sheet
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Date: December 07, 2005 12:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GliSODin® (The Antioxidant Catalyst) 100 mg Fact Sheet

GliSODin® (The Antioxidant Catalyst) 100 mg Fact Sheet Neil E. Levin, CCN, DANLA 01/31/05

LIKELY USERS: People with exposure oxidizing chemicals; People wanting to increase their body’s production of antioxidants.

KEY INGREDIENT (S): SOD (Superoxide Dismutase antioxidant enzyme) from melons Organic Wheat Grass leaf

MAIN PRODUCT FEATURES: Patented, clinically tested form of SOD to ensure absorbability; Protects cell mitochondria from oxidative stress that leads to genetic damage the cells; Reduces markers of cellular oxidative damage in the blood; May increase the body’s production of important antioxidants including SOD, Glutathione and Catalase.

OTHER IMPORTANT ISSUES: This product contains wheat protein as an aid to protecting the SOD and increasing its absorption. The base of organic wheat grass synergistically provides additional, naturally occurring levels of SOD and other nutrients, though this additional SOD is not well absorbed.

AMOUNT and HOW TO USE: One to three capsules a day, preferably between meals. If taken at mealtime avoid taking non-chelated (alkaline) forms of minerals at the same meal and take this capsule at the beginning of the meal to speed its transit time through the stomach and minimize exposure to alkaline foods and supplements that may cause the capsule to break down prematurely. That could potentially reduce the effectiveness of this form of SOD. The coating is designed to survive stomach acid and dissolve in the more alkaline conditions of the small intestine.

COMPLEMENTARY PRODUCTS: Alpha Lipoic Acid, EGCg Green Tea Extract, Whey Protein Isolate, Selenium, NAC, Vitamin C, other Antioxidants.

CAUTIONS: Contains wheat and wheat proteins, should not be used by people who are gluten-intolerant. Gluten intolerance may manifest with neurological, not abdominal symptoms, so please consider having a gluten intolerance test if you do have any neurological problems. Please notify your physician about your supplement use if you are using any drugs!

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCE:

Free Radic Res. 2004 Sep;38(9):927-32. Influence of an orally effective SOD on hyperbaric oxygen-related cell damage. Muth CM, Glenz Y, Klaus M, Radermacher P, Speit G, Leverve X. Sektion Anasthesiologische Pathophysiologie und Verfahrensentwicklung, Universitatsklinikum Ulm, D-89073 Ulm, Germany. PMID: 15621710 [PubMed - in process]



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Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
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Date: December 07, 2005 12:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet

Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue

KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients

MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.

Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.

Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.

OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.

AMOUNT TO USE: Three or more capsules a day, preferably with meals.

COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.

AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)

CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723–7 [in Hungarian].
3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol.) Orv Hetil 1990:131:863–6 [in Hungarian].
4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871–9.
5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179–80.
6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39–44.
7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson’s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189–202.
8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179–80.
9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153–5.
11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35–44.
12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719. 15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67. 18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
27. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
28. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
29. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.



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Rhodiola - Adaptogenic Herbs & Immunity Enhancers
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Date: December 06, 2005 09:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Rhodiola - Adaptogenic Herbs & Immunity Enhancers

If someone told you they knew of an herb that was a powerful antioxidant, supported the immune system, and regulated the neurotransmitters that help you deal with stress and its physical and psychological effects1,2,3,4, thereby improving the quality of your life, would you be interested? If you answered ‘YES’, then read on. That herb is available today, and it’s called Rhodiola.

Rhodiola (Rhodiola rosea), also known as “golden root”, is one of over 200 different species of Rhodiola, 20 of which are currently used in traditional medical systems in Asia. In fact, Rhodiola has been used in the traditional medical systems in Asia for hundreds of years as a means to stimulate the nervous system, decrease depression and fatigue, and even to help prevent high altitude sickness.

For the past quarter century, Russian and Scandinavian scientists have studied Rhodiola and its constituents. However, much of this research was unavailable to Western scientists until recently. Their research indicates that Rhodiola has diverse benefits on physiological functions, including central nervous system and cardiovascular function. Most of this research was done on Russian athletes.

In fact, it’s now known that Russian athletes used Rhodiola for many decades before Western medicine became aware of it, and it’s believed to be part of the reason Russian athletes were such formidable foes in athletic events of the past half century. Their ability to quickly adapt to the unique stress of athletic competition took on legendary proportions. And this was partially due to supplementation with Rhodiola.

The results of this research led them to classify Rhodiola as an “adaptogen”. The Russian scientist Lazarev (1947) established the criteria for an adaptogen3, and his definition is still valid today:

  • • An adaptogen produces a non-specific response in an organism; i.e. an increase in power of resistance against multiple stressors including physical, chemical and biological agents.
  • • An adaptogen has a normalizing influence on physiology, irrespective of the direction of change from physiological norms caused by the stressor.
  • • An adaptogen is incapable of influencing normal body functions more than required to gain non-specific resistance.
Basically, an adaptogen helps the body adjust to different stressors, and also helps the body to reassume homeostasis (the balance between various bodily functions and the chemical composition of fluids and tissues) once the stressor is no longer present2.

Rhodiola certainly fits these criteria, having shown beneficial results against stressors such as fatigue and nervous tension, as well as anxiety due to different factors such as intense study and dieting2. If these factors are limiting your effectiveness, then Rhodiola may be the answer you’re looking for.

So what does all this mean? It means that Rhodiola can offer generalized, non-specific resistance to physical, chemical and biological stressors you may experience every day, without affecting normal body functions, thereby enhancing the quality of life. Scientists believe that Rhodiola does this in part by promoting the release of certain neurotransmitters responsible for feelings of well-being, as well as regulating hormone production in response to stress1,2,3,4. It also appears to increase the permeability of the bloodbrain barrier to neurotransmitter precursors, aiding and even increasing their beneficial effects. “…the dual action of cognitive stimulation and emotional calming creates benefits for both immediate cognitive and memory performance and for the long-term preservation of brain functions.”

Rhodiola also imparts antioxidant protection by helping to protect the nervous system from oxidative damage by free radicals2. Chemical analysis of the genus Rhodiola has isolated a number of naturally occurring compounds found in the roots and above ground parts of the plant that provide Rhodiola’s adaptogenic properties. Rhodiola rosea differs from other species in the genus due to three unique phytochemicals that only occur in this particular species – rosavin, rosin, and rosarin (collectively referred to as rosavins). Researchers believe these phytochemicals are responsible for the unique characteristics found ONLY in the Rhodiola rosea species2,3. A good quality Rhodiola rosea supplement should be standardized to contain a minimum of 3% rosavins. Other species of Rhodiola don’t offer the same benefits.

In today’s world, stress is one of the most pervasive yet overlooked causes of poor health. NOW® Rhodiola helps the body deal with the adverse affects of stress with a potent, 500mg standardized extract containing 3% rosavins, the unique compounds that give Rhodiola rosea its amazing protective and antioxidant properties. Protect your body and mind with Rhodiola from NOW® Foods!

References

1) Ramazanov, Zakir & Appell, Brian; Rhodiola Rosea For Chronic Stress Disorder; National Bioscience Corporation, 2002

2) Brown, Richard P.; Gerbarg, Patricia L.; Ramazanov, Zakir; Rhodiola rosea: A Phytomedicinal Overview; HerbalGram: The Journal of the American Botanical Council, 56: 40-52

3) Kelley, Gregory S.; Rhodiola rosea: A Possible Plant Adaptogen (evaluation of therapeutic properties); Alternative Medicine Review, June 2001; 6(3): 293-302

4) Rhodiola (Rhodiola rosea (Golden Root, Arctic Root)); intramedicine website, Professional Monographs, January, 2001



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Weight Loss and Toxicity: The Missing Link
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Date: November 22, 2005 10:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Weight Loss and Toxicity: The Missing Link

We are THE toxic generation and therefore must become the DETOX GENERATION. The solution to all of the se conditions is to limit consumption of animal fats because most oil-soluble toxins accumulate in fat. The problem is not the saturated fat content found in animal foods, it’s the toxins that are stored in the animal’s fat. Choosing organic dairy and meats, as well as eating organic vegetables and fruits, is another helpful way to lower your exposure to fattening toxins. For good measure, it is imperative to fortify our intestinal tracts with good bacteria, because over 75 percent of the immune system’s receptor sites are located in the GI tract-so the GI tract, especially the colon, functions as a secondary immune system.

Here’s where a good probiotic can enter the picture. R. Fuller undertook the most recent and accurate description of probiotics in 1989 that redefined it as “a live microbial fee supplement beneficial to the host by improving the microbial balance within the body.” Think of a probiotic like you do your daily multi- it is, perhaps, even more essential.

Basically, there are over 100 trillion bacteria and around 400 different strains residing in your GI tract. The key is to have enough of the beneficial and essential bacteria. The optimum balance is 85 percent friendly bacteria to 15 percent unfriendly bacteria. And the trick is to make sure that if you take supplements for your probiotic needs, your supplement can really perform.

There are certain strains of lactic acid bacteria that can attach to your intestinal lining and produce antibodies that are lethal to the most disease producing bugs like the methicillin resistant staph, as well as E. coli (which is harbored in manure used as fertilizer and then shows up on your imported foods) and H. pylor-the bug that causes ulcers, heart disease, migraines, and glaucoma. Simply put, probiotics crowd out the bad bugs by occupying most of the parking space in the bowel wall.

The most promising probiotic strain to be discovered since Metchnikoff isolated the beneficial bacteria from yogurt is the TH10 strain researched and formulated by Dr. I. Ohhira, one of Japan’s leading microbiologists, and a team of research scientists from Okayama University.

The TH10 strain is now available here in the U.S. in a probiotic formula known as Dr. Ohhira’s probiotics 12 PLUS. I have been an educator for this product for nearly five years since I discovered it and have found that after one day, my sensitive stomach no longer experienced bloating, flatulence, and other assorted discomforts. The product utilizes primary research, not borrowed science.

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Chloride: The Forgotten Essential Mineral
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Date: November 20, 2005 07:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Chloride: The Forgotten Essential Mineral

Chloride: The Forgotten Essential Mineral

Chloride is an “essential” mineral for humans. It is abundant in ionic trace mineral preparations. It is a major mineral nutrient that occurs primarily in body fluids. Chloride is a prominent negatively charged ion of the blood, where it represents 70% of the body’s total negative ion content. On average, an adult human body contains approximately 115 grams of chloride, making up about 0.15% of total body weight.1 The suggested amount of chloride intake ranges from 750 to 900 milligrams per day, based on the fact that total obligatory loss of chloride in the average person is close to 530 milligrams per day. As the principle negatively charged ion in the body, chloride serves as one of the main electrolytes of the body. Chloride, in addition to potassium and sodium, assist in the conduction of electrical impulses when dissolved in bodily water. Potassium and sodium become positive ions as they lose an electron when dissolved and chloride becomes a negative ion as it gains an electron when dissolved. A positive ion is always accompanied by a negative ion, hence the close relationship between sodium, potassium and chloride. The electrolytes are distributed throughout all body fluids including the blood, lymph, and the fluid inside and outside cells.2 The negative charge of chloride balances against the positive charges of sodium and potassium ions in order to maintain serum osmolarity.

Pivotal Roles of Chloride in the Body

In addition to its functions as an electrolyte, chloride combines with hydrogen in the stomach to make hydrochloric acid, a powerful digestive enzyme that is responsible for the break down of proteins, absorption of other metallic minerals, and activation of intrinsic factor, which in turn absorbs vitamin B12. Chloride is specially transported into the gastric lumen, in exchange for another negatively charged electrolyte (bicarbonate), in order to maintain electrical neutrality across the stomach membrane. After utilization in hydrochloric acid, some chloride is reabsorbed by the intestine, back into the blood stream where it is required for maintenance of extracellular fluid volume. Chloride is both actively and passively absorbed by the body, depending on the current metabolic demands. A constant exchange of chloride and bicarbonate, between red blood cells and the plasma helps to govern the pH balance and transport of carbon dioxide, a waste product of respiration, from the body. With sodium and potassium, chloride works in the nervous system to aid in the transport of electrical impulses throughout the body, as movement of negatively charged chloride into the cell propagates the nervous electrical potential.

Deficiency of Chloride

Deficiency of chloride is rare. However, when it does occur, it results in a life threatening condition known as alkalosis, in which the blood becomes overly alkaline. A tedious balance between alkalinity and acidity is in constant flux, and must be vigilantly maintained throughout the entire body. Alkalosis may occur as a result of excessive loss of sodium, such as heavy sweating during endurance exercise, and in cases of prolonged vomiting and diarrhea. Symptoms include muscle weakness, loss of appetite, irritability, dehydration, and profound lethargy. Hypochloremia may result from water overload, wasting conditions, and extensive bodily burns with sequestration of extracellular fluids. In a situation in which infants were inadvertently fed chloride-deficient formula, many experienced failure to thrive, anorexia, and weakness in their first year of life.3

Excess Intake?

Excessive intakes of dietary chloride only occur with the ingestion of large amounts of salt and potassium chloride. The toxic effects of such diets, such as fluid retention and high blood pressure, are attributed to the high sodium and potassium levels.4 Chloride toxicity has not been observed in humans except in the special case of impaired sodium chloride metabolism, e.g. in congestive heart failure.5 Healthy individuals can tolerate the intake of large quantities of chloride provided that there is a concomitant intake of fresh water. Other situations in which increased blood levels of chloride are seen include diseases of improper waste elimination that occur in kidney diseases. Excess chloride is normally excreted in the urine, sweat, and bowels. In fact, excess urinary excretion of chloride occurs in high salt diets. Excessive intakes of chloride can occur in a person with compromised health in addition to an unhealthy diet. However, those that follow a healthy diet and lead an active lifestyle may need to consider supplementing their diet with this important mineral.

Chloride vs. Chlorine

The mineral supplement chloride is very different from the gas chlorine. While elemental chlorine is a dangerous gas that does not exist in the free elemental state in nature because of its reactivity, although it is widely distributed in combination with other elements. Chloride is related to chlorine however, as one of the most common chlorine compounds is common salt, NaCl. Chloride is a by-product of the reaction between chlorine and an electrolyte, such as potassium, magnesium, or sodium, which are essential for human metabolism. Chloride salts are essential for sustaining human metabolism and have none of the effects of isolated chlorine gas.

Sources of Chloride

Chloride occurs naturally in foods at levels normally less than 0.36 milligrams per gram of food. The average intake of chloride during a salt-free diet is approximately 100 milligrams per day. Unfortunately, chloride is found commonly combined with undesirable dietary sources. The most common of these negative sources is table salt. Table salt is made from a combination of sodium and chloride ions. Other unhealthful sources include yeast extracts, processed lunchmeats, and cheeses. Healthier sources of chloride include kelp (seaweed), ionic trace minerals, olives, rye, tomatoes, lettuce, and celery, although not in large enough amounts to supply the needs of an active adult.6 In its original form, however, chloride is leached from various rocks into soil and water by years of weathering processes. The chloride ion is highly mobile and is transported to closed basins, such as the Great Salt Lake, or oceans.7

Summary

Chloride is a highly important, vital mineral required for both human and animal life. Without chloride, the human body would be unable to maintain fluids in blood vessels, conduct nerve transmissions, move muscles, or maintain proper kidney function. As a major electrolyte mineral of the body, chloride performs many roles, and is rapidly excreted from the body. Active adults that eat a healthy diet devoid of salt and illnesses in which vomiting and/or diarrhea are profuse warrant the supplementation of additional chloride. Replacement of chloride is essential on a daily basis to maintain regular metabolic function. Chloride is safely utilized by the body, without negative health effects. Of the negative health effects that have been associated with diets high in chloride, these are mainly attributable to the accompanying sodium and potassium, two other electrolyte minerals to which chloride is often attached

--------------------------------------------------------------------------------

1 Wesson LG. Physiology of the human kidney. New York, NY, Grune and Stratton, 1969: 591

2 Weast RC, ed. CRC handbook of chemistry and physics, 67th ed. Boca Raton, FL, CRC Press, 1986.

3 Kaleita TA. Neurologic/behavioral syndrome associated with ingestion of chloride-deficient infant formula. Pediatrics 1986 Oct;78(4):714-5

4 Beard TC. A salt-hypertension hypothesis. J Cardiovasc Pharmacol 1990;16 Suppl 7:S35-8

5 Seelig M. Cardiovascular consequences of magnesium deficiency and loss: pathogenesis, prevalence and manifestations--magnesium and chloride loss in refractory potassium repletion. Am J Cardiol 1989 Apr 18;63(14):4G-21G

6 Altschul AM, Grommet JK. Food choices for lowering sodium intake. Hypertension 1982 Sep-Oct;4(5 Pt 2):III116-20

7 Gelb SB, Anderson MP. Sources of chloride and sulfate in ground water beneath an urbanized area in Southeastern Wisconsin (Report WIS01 NTIS). Chemical abstracts, 1981, 96(2):11366g.



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Ideal Vision from Thompson Nutritional
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Date: November 18, 2005 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ideal Vision from Thompson Nutritional

Ideal Vision Dietary Supplement is a powerful blend of antioxidants, vitamins, minerals and herbs formulated to provide nutritive support for healthy eyesite. Recent research suggests that supplementing with antioxidants such as zinc, vitamin C, vitamin E and betaCarotene may have potential beneficial effects on eye health in certain population groups.

- 15mg Lutein
- Includes Astaxanthin, Bilberry, and Other Important Antioxidants
- Incredible Price!

Supplement Facts:

  • Serving Size 3 tablets
  • Vitamin A (as natural mixed carotenoids isolated from the sea algae Dunaliella salina) - 25,000 IU
  • Vitamin C (as ascorbic acid) - 500mg
  • Vitamin E (as natural source 400 IU d-alpha tocopheryl succinate) - 400IU
  • Riboflavin (B-2) - 10mg
  • Zinc (as Zinc gluconate) - 80mg
  • Selenium (as selenium amino acid chelate) - 100mcg
  • Copper (as cupric oxide) - 2mg
  • N-Acetyl Cysteine (amino acid) - 100mcg
  • Bilberry (fruit extract)(supplying 9mg [36%] anthocyanosides) - 25mg
  • Lutein (as Marigold [tagetes erectus] flower extract)(Supplying 660mcg [4.4%] zeaxanthin) - 1mg
  • Astaxanthin (as astaxanthin complex from Haematococcus pluvialis extract) - 1mg





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Adverse Reactions to Foods and Dietary Supplements
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Date: August 27, 2005 08:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Adverse Reactions to Foods and Dietary Supplements

Adverse Reactions to Foods and Dietary Supplements

Answers to common Questions

The Journal of the American Medical Association reports that between 60,000 and 106,000 deaths per year in the United States are caused by prescription drugs. See JAMA, April 15, 1998 – Vol 279, No. 15. Fortunately, adverse reactions to foods and dietary supplements are far more rare than adverse reactions to drugs. However, we each consume a larger variety and quantity of foods than drugs. Because of this, and because each of us can react differently, an allergic or isolated reaction to a food or supplement is a possibility. Here’s helpful information about what to do if you or someone you care for has what appears to be an adverse reaction to a food or dietary supplement.

What types of reactions could I have?

The most common adverse reaction is an allergic reaction. In order to reduce the risk of an allergic reaction, carefully read all labels and buy products from reputable manufacturers who accurately disclose the ingredients in their products. If you need help finding these manufacturers, ask your local health food retailer for recommendations.

How do I know what caused my reaction?

Take time to carefully review what might have caused the reactions. Doctors and experts in toxicology look at several different factors in trying to determine the cause of a particular reaction.

Ask yourself:

1. Is this reaction a side effect of drugs I am taking?
2. Did I eat anything different in the last few days?
3. Have I used any new or unusual cosmetics or other personal care items?
4. Could my symptoms be related to an underlying illness?
5. Am I drinking to much coffee or alcohol or smoking to much?
6. Do I have a healthy diet?
7. Am I sleeping enough?
8. Have I been exposed to anything unusual in the air or my environment?

Asking your self these questions can help limit the number of possible causes and may lead you to an answer more quickly.

What should I do if I have an adverse reaction?

Weather or not you know the potential cause of the reaction, follow these steps:

  • • Seek immediate medical attention where appropriate. If the condition is serious or could become serious, call 911 or go to a hospital emergency room.
  • • Contact the manufacturer. Responsible manufacturers print a 1800 number on their product bottles and provide knowledgeable staff who can answer questions or direct you to appropriate answers or care. If your product doesn’t include a 1-800 number, contact the retailer where you purchased the product.
  • • Report the problem to the proper government agency. The FDA and other federal agencies are responseible for removing unsafe products from the market.

    How can I reach the FDA or another government agency about my concerns?

    Various state and federal agencies employ personnel who can help respond to concerns or questions about adverse reactions. Following is contact information for some of the agencies:

  • • For emergencies, call FDA at its main emergency number (1-301-443-1240), 24 hours per day.
  • • For non-emergencies, contact the consumer complaint coordinator at any FDA district office. A complete list of district office phone numbers can be found at: www.fda.gov/opacom/backgrounders/complain.html.

    How can I report an adverse event?

    FDA’s Center for Food Safety and Applied Nutrition (CFSAN) has an Adverse Event Reporting System (CAERS) that can be contacted in any of the following ways:

  • • By phone at 301-436-2405
  • • By email at CAERS@cfsan.fda.gov
  • • By mail at FDA,CAERS, HFS-700, 2A-012/CPK1, 5100 Paint Branch Parkway, College Park, MD 20740

    You can contact FDA’s MedWatch Program in any of the following ways:

  • • Online at www.FDA.Gov/medwatch/feedback.htm
  • • By phone at 800-FDA-1088
  • • By Mail with a postage-paid FDA form 3500, available at https://www.accessdata.fda.gov/scripts/medwatch/
  • • By sending it to: MedWatch, 5600 Fishers Lane Rockville, MD 20852-9787 Or sending it via fax to 1-800-FDA-0178

    For Non-emergencies related to products purchased via internet, fill out an online form on FDA’s website at vm.cfsan.fda.gov/~dms/qa-top.html (see link to “form to report unlawful sales”)

    You may also contact any local poison control center, local or state health agencies, the department of Health and Human Services, the Federal Trake Commision, the Consumer Products safety Commission, or the Centers for Disease Control and Prevention, and t hey will forward your report to the FDA.



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    Omega Man - For Men Interested in Optimal Health
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    Date: August 12, 2005 11:10 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Omega Man - For Men Interested in Optimal Health

    Omega Man

    For Men Interested in Optimal Health, Vitality and Staying Young

    Scientists have discovered the key that unlocks the door to a longer life, healthy weight, optimal athletic performance, and overall well-being. That key is composed of essential fats, called omega-3 fatty acids. You need these fats to balance the effects of the male hormone testosterone. Found in flax, pumpkin seeds, and other plants, omega-3 fats are essential to well-being, vitality, and optimal fitness; yet most men are deficient in the omega-3s.

    The low-fat and nonfat fads of the 1980s and 1990s taught nutrition experts a lot about the importance of omega-3 fats. As food manufacturers created one nonfat product after another, a strange thing happened- men got fatter and heart disease rates jumped.

    Since then, experts at research institutions including Harvard and the National Institutes of Health (NIH) have linked nonfat diets with depression, heart disease, weight gain, and poor physical performance.

    We now know that all fats are not created equal. Although some fats are indeed bad for our health, other fats are essential to overall health, vitality, and well-being. Most men, however, over consume the wrong fats- those found in processed foods and animal products- and do not consume enough of the right fats. To make matters worse, the good omega-3s are dwindling from the food supply. Food processing has stripped this important fat from our foods, making supplementation necessary.

    Thankfully, Omega Man from Barlean’s Organic Oils, a new whole food concentrate for men, will help reduce the risk of some of the most deadly and common men’s health problems. All men will benefit from Omega Man. Its blend of essential fats from flax, Styrian pumpkin seeds, and other sources complement one another, providing the optimal mix of the right types of fats, which promises to promote health and vitality no matter what your age.

    From the athletic pursuits of your early twenties to the health concerns of your fifties and beyond, Omega Man is an important part of a man’s healthy diet and will unlock the door to a new, more vibrant, healthier you.

    Recently, we’ve begun to report on the importance of certain men’s power foods and nutrients. By putting optimal amounts of these into men’s diets, men can ensure greater health and longevity.

    Super Health Blend

    Omega Man’s unique blend of flax, pumpkin and other fatty acid sources is an optimal formula for men’s health and vitality.

    Organic Flaxseed Oil

    Barlean’s award-winning organic omega-3 and lignan-rich flaxseed oil makes up the base of this formula and provides the richest and best-absorbed source of omega-3 fatty acids available. Other popular sources of omega-3 fatty acids, such as fish oil, may contain contaminants such as mercury and industrial chemicals. Barlean’s flaxseed oil, on the other hand, comes from organic seeds grown in optimal conditions with no chemicals, pesticides, or other contaminants. You can feel safe knowing that all of Barlean’s flaxseed oil products, including Omega Man, are pure and fresh. They help you promote optimal health without polluting your body.

    Lignans

    In addition to omega-3 fatty acids, Barlean’s lignan-rich flax oil is one of the world’s richest sources of lignans, important plant chemicals that act like hormones in the body. Lignans have been shown to bind to existing hormones in the body, bringing your hormones into the optimal balance needed for good health. Few men consume the amount of lignans needed to promote hormonal balance, making supplementation so important.

    Lignans serve in the body to block two critical enzyme systems that serve to initiate prostate cancer and benign prostatic hyperplasia. The first is aromatase, an enzyme that converts testosterone to a powerful testosterone derivative that is five times more powerful than its precursor in promoting prostatic disease. The second is 5-alpha reductase, and enzyme that converts testosterone to estrogen. Despite popular belief, estrogen is much more powerful in provoking prostate disease than testosterone. In fact, the ratio of testosterone to estrogen begins to weigh in favor of estrogen in the aging male. As testosterone levels decline with age, estrogen levels appear to remain relatively stable. Compared to younger men, the ratio of estrogen to testosterone is up to 40 percent higher in older men.

    Breakthrough research is implicating the imbalance between testosterone to estrogen as a primary cause of prostate disease. Flying in the face of past misconceptions, it would actually serve the aging male to increase testosterone at the expense of estrogen. It appears that this is exactly what lignans do in blocking the enzyme necessary for converting testosterone to estrogen. When the enzyme is blocked, testosterone is spared because it is not being converted to estrogen. In what you could visualize as a seesaw-like action, the ratio of testosterone to estrogen begins to move back in favor of testosterone.

    The action of lignans in sparing testosterone may hold greater implications than the obvious. Lack or loss of sexual desire in men and women is oftentimes associated with low testosterone levels. By preserving testosterone, many men and women may be able to retain or regain their sexual vigor. In fact, agents that block the conversion of testosterone to estrogen have been showing to increase testosterone levels by as much as 10 percent. (Speaking of sexuality, the surgical treatment of choice for prostatic disease (prostectomy) is the leading cause of impotency in men over 50. This fact alone should be powerful motivation for men of all ages to consider a supplemental regime to include lignans to lower the incidence of prostate cancer and benign prostatic hypertrophy.)

    The full significance of a “high-in-lignan” diet may be realized by the fact that lignans have been found isolated within prostatic fluids. Analytical work performed at a prominent cancer research center has indicated that the level of lignan in expressed prostatic fluid can be remarkable high, suggesting that it could well exercise a physiologic role within the gland. The glandular cells are certainly bathed in prostatic secretion for some considerable period, during which they could well influence cell biology. It has been established that the higher the intake of dietary lignans, the higher the physiologic lignan concentration in urine, blood plasma and prostatic secretions. The inference here is that the more dietary lignans that are ingested the more protection is offered in bathing the prostate gland in fluids high in protective lignans.

    Styrian Pumpkin Seed Oil

    Barlean’s went to the edge of the earth to procure the seeds of a rare and unique pumpkin found only in the region of southeast Austria. It is reputed for its extraordinary wealth of vitamins A, C, E, and K and high levels of phytosterols, all important for reducing risk of enlarged prostate and in the fight again cancer and heart disease.

    Phospholipid Concentrate

    Nearly every part of your body, from your internal organs to your cell membranes to your brain, contains phospholipids. Phospholipid supplementation has been shown to promote heart, digestive, liver, and brain health. Omega Man contains the optimal amounts of phospholipids for your health.

    Plant Phytosterol Complex

    Omega man is a rich source of the plant phytosterols betasitosterol, campesterol, and stigmasterol. If men have not begun to put phytosterols into their diet, then they’re missing out on an important natural food constituent that offers protection against toe most common cancers, that is an excellent remedy for enlarges prostate, and lowers cholesterol. Phytosterols are used widely in Europe to treat enlarge prostate (benign prostatic hyperplasia) and are known to lower the risk of cardiovascular disease by interfering with cholesterol absorption. Omega Man contains an optimal blend.



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    Nattokinase - Systemic Enzyme for Healthy Circulation
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    Date: August 03, 2005 05:38 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Nattokinase - Systemic Enzyme for Healthy Circulation

    NEW PRODUCT ANNOUNCEMENT

    Nattokinase—100 mg Capsules!

    Systemic Enzyme for Healthy Circulation

  • •A systemic enzyme isolated from the traditional Japanese soy food natto, now available in potent 100 mg capsules.
  • •Supports cardiovascular health and normal blood flow by assisting in the body’s circulatory clearing system; promotes normal fibrin levels in blood.
  • •Features high-grade NSK-SD™ NATTOKINASE, the most highly studied form of nattokinase recommended by leading researcher, Dr. Ralph E. Holsworth, Jr.
  • •Also available in 36 and 50 mg softgels.

    1 capsule contains:

    Nattokinase (NSK-SD™) 100 mg
    providing 2,000 fibrin units (FU) of activity

    Suggested Use: 1 capsule three times daily on an empty stomach with 8 ounces of water, or as recommended by your health care professional.



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    Celadrin - Benefits
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    Date: July 27, 2005 11:09 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Celadrin - Benefits

    Benefits

    Increased Range of Motion in Joints*

    Research has shown that Celadrin can have an impact on improving the range of motion in joints. A placebo-controlled trial conducted in 2002 showed that those individuals taking a complex containing Celadrin for 2 months had a significant improvement in knee flexion (ability to bend the knee) over those taking a placebo.1 Another study conducted on Celadrin published in 2004 concluded that treatment “significantly increased physical performance (as measured by a variety of orthopedic tests)” in patients with compromised knee mobility. The study found that the subjects given Celadrin showed improvement in their ability to climb stairs, rise from a chair and walk, along with an improved sense of balance, strength and endurance.3

    Maintains Joint Comfort*

    The anti-inflammatory actions of Celadrin have been demonstrated by one double-blind, placebo controlled trial that showed Celadrin, when taken orally at recommended intake levels, decreased pain scores and increased walking distance compared to the group receiving placebo. The authors theorize that Celadrin may work by down-regulating the effect of certain precursors of the body’s inflammatory response.1

    Safety

    Suggested Adult Use: One capsule three times daily, with or without food.

    Scientific References
    1. Hesslink R Jr., et al. Cetylated fatty acids improve knee function in patients with osteoarthritis. J Rheumatology 2002;8:1708-1712.

    2. Anonymous. Monograph: Glucosamine sulfate. Alt Med Review 1999;4:3;193-195.

    3. Kraemer WJ, et al. Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatology 2004;4:767-74.

    4. Crolle G, D'Este E. Glucosamine sulphate for the management of arthrosis: a controlled clinical evaluation. Curr Med Res Opin 1980;7:104-109.

    5. Rovati LC. Clinical research in osteoarthritis: design and results of short-term and long-term trials with disease modifying drugs. Int J Tissue React 1992;14:243-51. Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms, as discussed below.

    6. Bassleer C, et al. Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro. Osteoarthritis and Cartilage 1998;6:427-434. Med. 2002 Oct 14;162(18):2113-23.

    7. Reginster JY, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet 2001;357:251-56.

    8. Macario, J. T., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68. 9. Kraemer WJ, et al. Effect of acetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatol.2004 Apr;31(4):767-74. 10. Kraemer WJ,et al. Acetylated fatty acid topical cream with menthol reduces pain and improves functional performance in individuals with arthritis. J Strength Cond Res.2005 May;19(2):475-80.



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    Cancer fighter found in broccoli
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    Date: July 27, 2005 10:05 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cancer fighter found in broccoli

    Remember when your mother told you to eat your broccoli? Research shows that mother just might know best. In a recently published paper, Dr. Paul Talalay of Johns Hopkins University School of Medicine indicates that studies in his lab show broccoli is rich in sulforaphane, a chemical that works as a powerful anti-cancer compound in laboratory mice.

    Other studies have shown that a diet rich in cruciferous vegetables—which include broccoli, Brussels sprouts, cabbage, cauliflower, and others— can significantly reduce the risk of cancer of the bowel, stomach and breast. Until now, the exact reasons why these vegetables had this effect we re not very clear. Until now, that is. According to Dr. Talalay, it appears that at least one anticancer ingredient in the vegetables is sulforaphane, which essentially causes cells to expel cancer-causing toxins. In addition, Dr. Talahay said that this study was the first to show that a high-potency compound isolated from vegetables could accelerate the detoxification process in cells.

    The published report outlines how the research team isolated sulforaphane from broccoli, then fed it to a group of mice. When cells in the mice we re examined after five days, the scientists found that the chemical had triggered enzymes known to neutralize carcinogens within cells. Be yond this study, Dr. Talalay indicates that research will shift to the long-term effects of the chemical. “Our prediction is that sulforaphane will block tumor formation in animals and presumably in man.” In earlier studies, Dr. Talalay and others have shown that certain proteins in cells, called phase I enzymes, can take innocent chemicals and turn them into cancer-causing agents.

    Other proteins, called phase 2 enzymes, tend to block formation of carcinogens. According to the study, sulforaphane is a potent activator of phase 2 enzymes. The Hopkins researchers will conduct tests to determine how much broccoli must be consumed to establish an effective anti-cancer level of sulforaphane in cells.

    Over a decade of research has been done on cruciferous vegetables and there are large databases that confirm that cruciferous vegetables substantially reduce the risk of disease, specifically cancer. Studies show substances in these vegetables that have anti-cancer properties which cause the body to speed up production of enzymes, therefore being capable of neutralizing cancer agents. The studies also show these pre vent damage to our DNA and slow the aging process. In women, metabolic processes are regulated which eliminate the bad (and maintain the good) estrogen, therefore substantially reduce the risk of breast cancer. Shortly after the NCI study was released, John Hopkins School of Medicine revealed similar studies.



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    WILD YAM: NATURE’S ANSWER TO HORMONAL IMBALANCES
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    Date: July 25, 2005 09:52 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: WILD YAM: NATURE’S ANSWER TO HORMONAL IMBALANCES

    WILD YAM: NATURE’S ANSWER TO HORMONAL IMBALANCES

    In 1985 Rudolf Weiss wrote, “Wild yams contain diosgenin, a precursor in the synthesis of progesterone, and are the only known available source.”3 Mexican wild yam is the richest phytoestrogen available and provides the human body with a natural and safe source of progesterone. It has an anti-spasmodic action which make is ideal for treating menstrual cramping and is an excellent contributor to achieving glandular balance. Native Americans have used wild yam for generations for the treatment of female disorders and as a supportive herbal for pregnancy. In 1936, Japanese scientists discovered the glycoside saponins found in several wild yam species from which steroid saponins (diosgenin) could be extracted.4 Diosgenin is remarkably similar to progesterone it its chemical configuration. Because of its steroidal saponins, wild yam has been used for hundreds of prescription drugs including some birth control pills; however, these forms of the plant have been chemically isolated and altered resulting in variations of the plant’s natural compounds. These artificially manipulated chemicals can initiate abnormal responses in the human body, a fact which accounts for their long list of risks and side effects. Synthetic forms of progesterone whether derived from wild yam or not are not the same as an extract of the whole wild yam. It’s useful to know that products listing wild yam as an ingredient may not included the saponin-rich portion of the yam root. Progesterone which is derived from wild yam is almost identical in its chemical structure to the natural progesterone synthesized by the human body. When wild yam is absorbed into the body it is easily converted into the same molecule, a process which does not occur with synthetic varieties.

    The transition is easy and natural. Wild yam in and of itself does not contain simple progesterone or other steroids, but serves as a precursor to these compounds. The phytoestrogen character of wild yam explains its traditional usage for menstrual cramping, dysmenorrhea, and afterbirth pains.

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    FORMS OF STEVIA
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    Date: July 15, 2005 12:51 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: FORMS OF STEVIA

    FORMS OF STEVIA

    Stevia has traditionally been used in either a powder or raw liquid form. Powdered forms can either be crude green or fine and white. Powders come in bulk or in tea bags. White stevia powder is the most common type and usually has more sweetening power than other forms. Countries like Japan use a filler substance along with stevia powder in order to give it more substance and make it easier to package. Powdered forms can be somewhat difficult to measure, although they are considered quite practical. Liquid formulas which are often brown in color frequently add other compounds to counteract bitterness. Alcohol based extracts are also available, as well as new concentrated liquid varieties. White stevia powder is the most popular form of the sweetener, although the leaf, ground or whole, can be purchased loose or in tea bags. Fresh leaves can be chewed but they are not practical for sweetening other foods. Dried leaves can used used for teas or in tea blends. Stevia tablets are also available for those who want to use the herb as a therapeutic rather than sweetening agent. Ground stevia can be sprinkled over cereals, salads, and other ready-toserve foods. (NOTE: Stevia powders can vary in their sweetening strength, which is determined to a great degree by the refining process and the plant quality.) If you choose to buy stevia leaves, they can widely vary in their quality and content depending on their cultivation and environmental conditions. The stevioside and rebaudidoside contents can also differ and bacterial or fungal contamination can be a problem. For this reason purchase stevia products only from reliable sources. Buying stevia in white powder or liquid extract forms from reliable distributors is also recommended.

    Stevioside

    Stevioside is the most powe rful form of the stevia glycoside and is usually available in either a white powder or liquid extract. It is the isolated glycoside form of stevia and is used specifically for its sweetening ability and not for any therapeutic applications. Japanese consumers use stevioside extensively.

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    WOUNDS AND ST. JOHN'S WORT
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    Date: July 15, 2005 09:29 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: WOUNDS AND ST. JOHN'S WORT

    WOUNDS

    St. John’s wort oil has long been held in high esteem for treatment of all types of abrasions and wounds. Its fame was reputedly tested time and time again on the battlefields of the Crusades. More modern tests using the oil have proved its reputation. The oil, which does not contain hypericin, contains another valuable compound, hyperforin, which is mainly responsible for the oil’s therapeutic properties. Though somewhat difficult to isolate and preserve for extended periods of time, hyperforin has shown considerable promise as a primary component in salves or dressings for topical and other wounds. It only makes sense that in being able to withstand and inhibit bacterial and viral growth, St. John’s wort can effectively aid topical wounds in their healing and recovery.

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    ST. JOHN’S WORT AND AIDS/HIV
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    Date: July 15, 2005 09:28 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: ST. JOHN’S WORT AND AIDS/HIV

    ST. JOHN’S WORT AND AIDS/HIV

    In 1991, some of the first work focusing on St. John’s wort’s effects on AIDS and the HIV virus began. Science magazine reported on the first study using the isolated hypericin, a key compound in Hypericum.16 Fred Valentine and Howard Hochster, researchers at New York University Medical Center, began one of the first studies looking at how hypericin can help uninfected T-cells from being infected with the AIDS virus in a cell culture. Their focus was on hypericin because it is a virucidal agent, meaning it can precisely target new virus particles and prevent them from infecting other cells.

    The only two drugs at that time approved for treating HIV infection—AZT and ddI—work by interfering with the key viral enzyme, reverse transcriptase. Since hypericin works more effectively than many drugs in regards to the reverse transcriptase phase, and since many animal tests have shown that it has low toxicity at therapeutic doses, researchers (including Valentine and Hochster) began these studies largely hoping that not only would hypericin work on its own, but that it would have a sort of synergistic effect when used with either AZT or ddI. 17

    Additional studies are pointing to St. John’s wort, and more so, hypericin, as having great potential in treating HIV. Acosta and Fletcher recently detailed the processes in which the human immunodeficiency virus works to infect human cells, and point out that hypericin is at least somewhat effective in inhibiting the four main phases of virus “growth”— binding and entry, reverse transcriptase, transcription and translation, and viral maturation and budding (the researchers note that hypericin is especially effective in binding and entry, the first phase.) This denotes that hypericin could eventually have special importance in completely stifling the development of the growth of any virus, and most importantly, that of the HIV virus.18

    Another study assessing the use and attitudes of HIV sufferers concerning the use of more alternative treatments for the virus as opposed to clinical drug therapies showed both an extensive use of unconventional therapies and a very favorable response to using the alternative treatments, which, of course, St. John’s wort was among. “Participants at all sites expressed positive views upon increasing unconventional remedies.”19 The fact is that the world of synthetic medicines has been basically ineffective in not only treating and relieving the symptoms of AIDS, but also in finding a cure for the dreaded disease. Sufferers are giving alternative therapies a try, and the results are very promising.

    A 1995 review appearing in Photochemisty-Photobiology treated the photodynamic properties of both hypericin and the structurally related hypocrellins for their anticancer and antiviral properties (especially the anti-human immunodeficiency virus). This article states that the promising anticancer and antiviral results obtained both in vitro and in vivo [in differing studies] have led to intensive investigation into their photo-physical and photochemical processes, especially kinetic studies of their intramolecular proton transfer . . . The biomedical advances of hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericin.20

    Another study published in the September 1994 issue of Photochemistry-Photobiology gave hypericin the upper hand over the hypocrellins in treating HIV. Just one more vote in favor of promoting the use of St. John’s wort, and more specifically, hypericin, for use in treating HIV and in overall clinical medicine.

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    HYPERICIN
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    Date: July 14, 2005 10:46 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HYPERICIN

    HYPERICIN

    One of the reasons St. John’s wort is attracting so much interest is because of one of its compounds, hypericin. The journal Photochemistry-Photobiology recently published a review of hypericins and the structurally related hypocrellins, giving a favorable outline of the various recent breakthroughs in medicine using these two compounds. The review states, Hypocrellins and hypericins, structurally related plant pigments isolated from Hypocrella bambuase and Hypericum respectively, are known photodynamic agents. This review summarizes certain significant advances in the phtotophysics, photochemistry and photobiology of these pigments in the last two years and discusses their prospects as novel therapeutic and diagnostic agents in the future . . . In particular, substantial progress has been made in both anticancer and antiviral applications (especially anti-human immunodeficiency virus). . . . The biomedical advances of hypocrellins and hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericins.2 The compound hypericin was isolated from St. John’s wort in 1942 and has been used as an anti-depressant and mood stabilizer for emotionally and mentally disturbed people.

    Among its many beneficial qualities is that of increasing blood flow to stressed tissue, thereby having a tranquilizing effect. It also reduces the fragility of capillaries and enhances uterine muscle tone because of its ability to increase blood flow.3 It is this compound that is being extensively researched for its possible therapeutic properties for a variety of diseases, mainly depression, AIDS and other viruses, cancer and sleep disorders.

    Extensive research has been done, especially recently, to determine exactly how hypericin works in treating these and other disorders. Nearly all the researchers are saying the same thing—that Hypericum (and specifically hypericin) promises significant value to the medical world in overcoming these serious disorders. The following sections discuss the various disorders that are being researched in conjunction with Hypericum/ hypericin therapy.

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    THE ORIGINS OF PYCNOGENOL
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    Date: July 13, 2005 09:48 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: THE ORIGINS OF PYCNOGENOL

    THE ORIGINS OF PYCNOGENOL

    For generations, certain tribes of North American Indians used bioflavonoids extracted from the bark of pine trees for a variety of disorders. Because of its marvelous healing properties, they called this pine the Annedda, or “tree of life.”

    PINE BARK: GIVER OF LIFE

    These native Americans, who routinely ate deer as their primary source of nutrition, when confronted with a scarcity of meat asked themselves ... where does the deer get its strength? They discovered that deer stripped away pine tree bark and we re able to derive life-giving nutrients from its organic composition. It was also observed that devastating diseases such as scurvy did not afflict those who ate the bark, leaves or needles of this pine tree.

    CARTIER’S ENCOUNTER WITH ANNEDDA TEA

    In 1535, Jacques Cartier learned of the medicinal value of the bark, which remained relatively unknown until 20 or 30 years ago, when scientists reviewed his notes and commenced research. Cartier became caught in the bitter snows of Quebec, while attempting to navigate the St. Lawrence River. Cartier and his crew subsisted on hard biscuits and cured meat and eventually came down with what was believed to be scurvy. Scurvy is an abhorrent disease which causes a very slow and agonizing death. Several of Cartier’s men died before they were approached by the Quebec Indians who prepared a tea they called “Annedda” from the bark of a certain native pine tree. The men took the tea and used its leaves as poultices. Their recovery was almost immediate. What must have seemed like a miraculous substance was technically, nothing more than vitamin C with bioflavonoids naturally inherent to the pine tree.

    MASQUELIER’S SUBSEQUENT DISCOVERY OF PYCNOGENOL

    Cartier was resourceful enough to document the incident. Over 400 years later, a French professor, Jacques Masquelier, assigned to the University of Quebec discove red Cartier’s account. Because he was already involved in bioflavonoid research, he became greatly intrigued by pine tree extract. Dr. Masquelier isolated a bio-active substance known as proanthocyanidin.

    THE EMERGENCE OF PROANTHOCYANIDIN

    After returning to France, Professor Masquelier found that this compound could be extracted from the bark of the French Maritime Pine pinus maritima found in abundance in southern France. Intensive research by Dr. Masquelier led to the discovery of Pycnogenol, which is another name for the group of bioflavonoids known as the proanthocyanidins. Subsequent in-depth testing revealed that these compounds are a nutrient treasure far more valuable that anyone originally thought. In time, the grape seed was found to contain the same compound and today, is considered an excellent source of Pycnogenol in France.

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    HAWAIIAN NONI (Morinda citrifolia)
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    Date: July 11, 2005 08:50 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HAWAIIAN NONI (Morinda citrifolia)

    INTRODUCTION

    In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:

  • • protect ourselves f rom toxins and pollut ants
  • • prevent t he premature onset of age-related diseases such as arthritis, heart disease, diabetes and stroke
  • • boost our immune defenses to protect ourselves from new viral and bacterial strains that have become antibiotic-resist ant
  • • reduce our risk of developing cancer
  • • better digest our food for proper assimilation and purge the intestinal system wit hout the dangerous side effects of harsh drugs. Its actions are multifaceted and must be considered when assessing natural treatment s for disease or injury. It s impressive and widespread use among various native cult ures of t ropical island regions supports the notion that it does indeed possess valuable, therapeutic compounds.

    Genus Rubiaceae

    Common Names

    Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.

    Parts Used

    The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.

    Physical Description

    Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.

    Chemical Constituents

    Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.

  • • amino acids (which include alanine, arginine, asparticacids, cysteine, cystine, glycine, glutamic acid, histidine, leucine, isoleucine, methionine, phenylalanine, proline, serine, threonine, tryptophan tyrosine, and valine)
  • • anthraquinones
  • • glycosides
  • • phenolic compounds
  • • resins
  • • B-sitosterol
  • • ursolic acid

    FLOWER

  • • acacet in 7-0-D (+) -glucophyranoside
  • • 5,7,-dimet hylapigenin-4-0-8-D(+) -galactophyranoside
  • • 6,8,-dimet hoxy-3-methyl anthroquinone-1-0-8-rhamnosyl glucophyranoside

    FRUIT

  • • antioxidant
  • • alizarin
  • • anthraquinones
  • • caproic and caprylic acids

    discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.

    ROOT AND ROOT BARK

  • • carbonate
  • • chlorubin
  • • rubicholric acid
  • • soranjidol
  • • chrysophanol
  • • phosphate
  • • magnesium
  • • ferric iron
  • • sodium
  • • glycosides
  • • morinadadiol
  • • morindine
  • • resins
  • • rubiadin
  • • sterols4

    Pharmacology

    Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.

    Body Systems Targeted

    The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.

    Satety

    Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.

    Suggested Uses

    Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .

    NONI: ITS USE AND HISTORY

    Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .

    Wonder Herb of Island Folk Healers

    Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.

    Noni’s Medical Reputation

    Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.

    A Timely Reemer gence

    Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.

    TRADITIONAL USES OF NONI

    Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15

    decoctions to stimulate delayed menst ruation.

  • • Noni was frequently utilized for its antiparasitic activity.
  • • Respiratory ailments, coughs, and colds were treated with noni.
  • • A juice made from pounding noni leaves, roots and fruit mixed with water was administered for diarrhea.
  • • Dried and powdered forms of the bark mixed with water and administ ered with a spoon treated infant diarrhea.
  • • Small pieces of fruit and root infused with water were given to kill intestinal parasites.
  • • Boiled bark decoctions were given as a drink for stomach ailments.
  • • Coughs were treated with grated bark.
  • • Charred unripe fruit was used with salt on diseased gums.
  • • Pounded fruit combined with kava and sugar cane was used to treat tuberculosis.
  • • Babies were rubbed with fresh, crushed leaves for serious chest colds accompanied by fever.
  • • Eye washes were made from decoctions for eye complaint s from flower extracts.
  • • Leaf infusions were traditionally taken to treat adult fevers.
  • • A mouthwash consisting of crushed ripe fruit and juice was used for inflamed gums in young boys.
  • • Pounded leaf juice was used for adult gingivitis.
  • • Sore throats were treated by chewing the leaves and swallowing the juice.
  • • Skin abscesses and boils were covered with leaf poultices.
  • • Swelling was controlled with leaf macerations.
  • • Heated leaves were often used for arthritic joins and for ringworm.16

    XERONINE: THE SECRET OF NONI?

    One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .

    Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18

    NONI PROCESSING

    How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.

    MODERN APPLICATIONS OF NONI

    Overview

    Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.

    Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.

    xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.

    Cancer

    A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21

    In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.

    Arthritis

    with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.

    Immune System

    The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.

    The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.

    Antioxidant

    The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.

    Diabetes

    While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.

    Pain Killer

    A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29

    Skin Healing Agent

    One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.

    burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30

    Drug Addiction

    The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.

    Complementary Agents of Noni

  • cat’s claw papaya
  • kava kava
  • pau d’arco
  • bioflavonoids
  • selenium
  • germanium
  • grapeseed extract
  • echinacea
  • proteolytic enzymes
  • aloe vera
  • glucosamine
  • shark
  • cartilage

    PrimaryApplications of Noni

  • abrasions
  • arthritis
  • atherosclerosis
  • bladder infections
  • boils bowel disorders
  • burns cancer
  • chronicfatigue syndrome
  • circulatory weakness
  • colds congest ion
  • cold sores constipation
  • depression diabetes
  • eye inf lammations fever
  • fract ures gastric ulcers
  • gingivit is headaches
  • high blood pressure immune
  • weakness
  • indigestion intestinal parasites
  • kidney disease menstrual



    --
    Vitanet ®

    Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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    Cinnamon may control sugar levels...
    TopPreviousNext

    Date: July 08, 2005 10:48 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cinnamon may control sugar levels...

    Best Cinnamon

  • Use as Part of Your Diet to Help Maintain a Healthy Blood Sugar Level*
  • HUMAN CLINICAL TRIALS
  • Cinnamon,
    a staple ingredient in apple pie, has remained one of the
    world's favorite spices throughout recorded history. The
    evergreen cinnamon tree (Cinnamomum verum), considered to be
    true cinnamon, is native to Sri Lanka. Chinese cinnamon
    (Cinnamomum cassia or Cinnamomum aromaticum), the cinnamon most
    commonly sold in the U.S., goes by the name “Cassia.” Usage of
    cinnamon in Chinese medicine is said to date back over 4,000
    years. Mentioned in the Bible, cinnamon was imported to Egypt
    and Europe from the Far East by 500 B.C. In addition to its
    value as culinary spice, cinnamon has traditionally been
    utilized as a folk medicine for colds and minor digestive
    complaints. True cinnamon and cassia are very similar; cassia
    has a more pungent flavor. Cassia buds can be found in potpourri
    and used as a flavoring agent in sweets and
    beverages.1

    Recent research has revealed that constituents in
    cinnamon bark called procyanidin Type-A polymers help maintain
    the body's ability to metabolize glucose in a healthy way.* Best
    Cinnamon Extract is Cinnulin PF®, a patented, water extract of
    Cinnamon that contains Type-A polymers. Cinnulin PF® is a
    registered trademark of Integrity Nutraceuticals International
    and is manufactured under US Patent #
    6,200,569.

    Benefits

    Use as Part of Your Diet to Help
    Maintain a Healthy Blood Sugar Level*

    In Vitro and Animal
    Studies

    Research has revealed that a number of herbs and
    spices have insulin-like activity.2 In a study by the U.S.
    Department of Agriculture (USDA), cinnamon demonstrated the
    greatest ability to stimulate cellular glucose metabolism among
    49 botanicals tested.3

    In a 2001 study, researchers at the
    USDA's Human Nutrition Research Center showed that bioactive
    compounds in cinnamon trigger an insulin-like response in fat
    cells.4 These compounds stimulated glucose uptake into cells and
    increased glycogen (stored glucose) production via activation of
    the enzyme, glycogen synthase.

    The bioactive compounds in
    cinnamon appear to potentiate insulin activity at the level of
    the cell receptor for insulin. It has been shown that insulin
    resistance involves down regulation of “insulin signaling”
    characterized by dephosphorylation of the receptor.5 Enzymes
    called “protein tyrosine kinases” (PTPases) are believed to
    decrease receptor phosphorylation, and increased PTPase activity
    has been observed in insulin resistant rats.6 Cinnamon compounds
    have demonstrated the in vitro ability to inhibit PTP-1 and
    increase autophosphorylation of the insulin receptor.7

    In a
    recent animal study, cinnamon (cassia) extract was administered
    to rats for three weeks. Following this, the rats were infused
    with insulin and glucose to assess their insulin response.
    Increased phosphorylation of the insulin receptor was observed
    in skeletal muscle of these rats, suggesting that cinnamon has
    the ability to potentiate insulin function by normalizing
    insulin signaling, leading to improved uptake of glucose into
    skeletal muscle.8

    Until recently, the precise molecular
    structure of the bioactive compounds in cinnamon had not been
    clearly defined. The USDA has now determined that the bioactive
    compounds in cinnamon are water-soluble procyanidin Type-A
    polymers of catechin and epicatechin. In a 2004 study, type-A
    polymers were isolated from cinnamon and characterized by
    nuclear magnetic resonance and mass spectroscopy. Type-A
    polymers were found to increase in vitro insulin activity by a
    factor of 20. Type-A polymers also exhibited antioxidant
    activity, as measured by inhibition of free radical production
    in platelets. These results suggest that, in addition to
    regulating glucose metabolism, cinnamon may help protect cell
    membranes by controlling the lipid peroxidation associated with
    disruptions in insulin function.9

    HUMAN CLINICAL TRIALS

    The effect of cinnamon on glucose and blood lipids
    levels on people with type 2 diabetes was tested in a recent
    randomized, placebo-controlled trial. A total of 60 subjects
    were divided into six groups administered 1, 3, or 6 grams of
    cinnamon daily, in 500 mg capsules, or equal numbers of placebo
    capsules.

    The cinnamon or placebo capsules were consumed for
    two periods of 20 days each. Serum glucose, triglyceride,
    cholesterol, LDL cholesterol and HDL cholesterol were measured
    after 20 days, 40 days and again at the end of a 20-day wash-out
    period, during which neither cinnamon nor placebo was
    consumed.

    In all three cinnamon groups, statistically
    significant reductions in blood glucose levels occurred, with
    decreases ranging from 18 to 29 percent. Interestingly, glucose
    levels remained significantly lower after the 20-day wash-out
    period (60 days from the study start) only in the group that
    took the lowest cinnamon dose (1 gram daily). The placebo groups
    showed no significant changes.

    Decreases in triglyceride
    levels ranging from 23 to 30% were observed in all three
    cinnamon groups after 40 days. When the study ended at 60 days,
    triglyceride levels remained lower than at the study start in
    the 1 and 3 gram cinnamon groups, but not in the group taking 6
    grams daily. Cholesterol reductions also occurred with the three
    cinnamon doses, with decreases ranging from 13 to 25% that were
    maintained at the study end. For LDL, the 3 and 6 gram cinnamon
    groups showed significant reductions from 10 to 24%, while in
    the 1 gram cinnamon group, non-significant reductions occurred
    after 40 days; LDL levels continued to decrease, reaching
    statistical significance at 60 days. With respect to HDL,
    significant increases were seen only in the 3 gram cinnamon
    group after 20 days; non-significant changes occurred in the 1
    and 6 gram groups after 40 days.

    The overall results of this
    trial demonstrate that cinnamon exerts a beneficial effect on
    blood glucose and lipid levels in people with type 2 diabetes,
    at daily intakes of 1 gram, and that this low dose is equally
    efficacious as are the higher doses of 3 and 6
    grams.10

    Safety

    The various species of cinnamon are
    classified as GRAS (generally regarded as safe) herbs.11 The
    Botanical Safety Handbook lists Cinnamomum cassia a “Class 2b”
    herb; not to be used during pregnancy.12 The water-soluble
    cinnamon extract is largely free of the lipid-soluble components
    of cinnamon most likely to be toxic at high dose of cinnamon and
    long-term consumption of the herb.9

    *This statement has not
    been evaluated by the Food and Drug Administration. This product
    is not intended to diagnose, treat, cure or prevent any
    disease.

    Scientific References

    1. Manniche, L. An Ancient
    Egyptian Herbal. 1989, Austin , TX : University of Texas
    Press.

    2. Khan A, Bryden NA, Polansky MM, Anderson RA.
    Insulin potentiating factor and chromium content of selected
    foods and spices. Biol Trace Elem Res 1990;24(3):183-8.

    3.
    Broadhurst CL, Polansky MM, Anderson R. Insulin-like biological
    activity of culinary and medicinal plant aqueous extracts in
    vitro. J Agric Food Chem 2000;48(3):849-52.

    4. Jarvill-Taylor
    KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from
    cinnamon functions as a mimetic for insulin in 3T3-L1
    adipocytes. J Am Coll Nutr 2001;20(4):327-36.

    5. Nadiv O,
    Shinitzky M, Manu H, et al. Elevated protein tyrosine
    phosphatase activity and increased membrane viscosity are
    associated with impaired activation of the insulin receptor
    kinase in old rats. Biochem J. 1998;298(Pt 2):443-50.

    6.
    Begum N, Sussman KE, Draznin B. Differential effects of diabetes
    on adipocyte and liver phosphotyrosine and phsophoserine
    phosphatase activities. Diabetes 1991;40(12):1620-9.

    7.
    Imparl-Radosevich J, Deas S, Polansky MM, et al. Regulation of
    PTP-1 and insulin receptor kinase by fractions from cinnamon:
    implications for cinnamon regulation of insulin signalling. Horm
    Res 1998;50:177-182.

    8. Qin B, Nagasaki M, Ren M, et al.
    Cinnamon extract (traditional herb) potentiates in vivo
    insulin-regulated glucose utilization via enhanced insulin
    signaling in rats. Diabetes Res Clin Pract
    2003;62(3):139-48.

    9. Anderson R, Broadhurst CL, Polansky MM,
    et al. Isolation and characterization of polyphenol type-A
    polymers from cinnamon with insulin-like biological activity. J
    Agric Food Chem 2004; 52(1):65-70.

    10. Khan A, Safdar S,
    Muzaffar M, et al. Cinnamon improves glucose and lipids of
    people with type 2 diabetes. Diabetes Care
    2003;26(12):3215-18.

    11. Duke, JA. Handbook of Phytochemical
    Constituents of GRAS Herbs and Other Economic Plants. 1992. Boca
    Raton, FL: CRC Press.

    12. Botanical Safety Handbook. American
    Herbal Products Association. McGuffin M, et al., eds. 1997; Boca
    Raton , FL : CRC Press.

    Acting as a biochemical
    "super-thiamin," it does this through several different cellular
    mechanisms, as discussed below.



    --
    Vitanet ®

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    Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story
    TopPreviousNext

    Date: June 29, 2005 09:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story

    Hoodia Gordonii - 20:1 Extract VS 1:1 Powder – The Whole Story

    The hoodia landscape has been unnecessarily clouded recently thanks to the misinformation circulating about concentrated extracts and socalled “100%” hoodia powder. Most of the information is highly subjective, with no studies whatsoever to support claims that socalled “pure” powder is more efficacious than 20:1 concentrated extracts. In fact, purporting to offer 100% hoodia powder is a dubious claim at best, with some groups offering little in the way of solid evidence that theirs is actually authentic Hoodia gordonii grown in South Africa and imported to the United States legally with proper permits. Propagating the false notion that “more is better” is a risky, uncertain gamble if you’re not precisely sure what exactly you’re getting more of! At Source Naturals, a trusted company with years of experience and demonstrated excellence in nutritional supplements, we believe that nothing tops quality assurance.

    Extraction – The Bottom Line

    Much of the misunderstanding surrounding hoodia extracts directly corresponds to a common misperception that the word extract is mutually exclusive to standardization – a method of extraction that isolates and removes a constituent part of an herb or botanical for use in supplements to control potency. Unfortunately the ambiguity of the term “extract” in relation to hoodia products has led to uninformed claims that hoodia extracts somehow contain less essential Hoodia gordonii plant parts, which is patently false, and underscores the inherent confusion as to how high-quality concentrated hoodia powder is actually produced. Simply put, many of the truly effective hoodia products on the market are, by their very nature, extracts – whether they claim to be or not. That is because the concentration process by which the whole parts of the hoodia plant become dried powder is an extraction. Calling it anything but an extract would be, frankly, disingenuous.

    The Process

    Hoodia gordonii is a succulent containing excess moisture that needs to be removed in order to make an effective, concentrated powder. The process by which that moisture is removed to yield the powder is called an extraction. This process, however, is different from standardized extraction. This process does not remove a single component from the plant; rather it separates the water from the solid parts of the plant, making a concentrated powder for a more powerful, effective product.

    The End Result

    The raw materials used to make HOODIA EXTRACT have not been added to, nor have we attempted to specifically extract any constituent parts of the plant to regulate potency. What we have done is taken high-quality, authentic, certified material from one of the industry’s most respected suppliers of Hoodia gordonii and held it to our own high standards of Total Quality Assurance (TQA™) in making a supplement with 20 times more functional hoodia than had we ground the plant up water and all. By putting it through stringent testing procedures in our quality control lab we have assured our product’s quality and efficacy. The Hoodia gordonii we receive is carefully scrutinized; put through High Performance Thin Layer Chromatographic (HPTLC) analysis for authenticity, and microbiological screening for contamination, as well as other rigorous laboratory protocols.

    Quality = Results

    When you buy Source Naturals HOODIA EXTRACT, you can be assured that you’re not just getting an effective, natural dietary supplement, you’re getting part of an almost 25- year old tradition in providing quality products that support your good health. So before you buy into “more = better,” remember the Source Naturals edict: Quality = Results. Source Naturals – dedicated to excellence, committed to you.



    --
    Vitanet ®

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    CHITOSAN: The Fiber that Binds Fat
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    Date: June 25, 2005 07:55 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CHITOSAN: The Fiber that Binds Fat

    Overview

    Chitosan is a natural product that inhibits fat absorption. It has the potential to revolutionize the process of losing weight and by so doing, reduce the incidence of some of the most devastating Western diseases we face today. Chitosan is indigestable and non-absorbable. Fats bound to chitosan become nonabsorbable thereby negating their caloric value. Chitosan-bound fat leaves the intestinal tract having never entered the bloodstream. Chitosan is remarkable in that it has the abilty to absorb an average of 4 to 5 times its weight in fat.60

    The same features that allow chitosan to bind fats endow it with many other valuable properties that work to promote health and prevent disease. Chitosan is a remarkable substance whose time has come.


    Chitosan: A Brief History

    Chitin, the precursor to Chitosan, was first discovered in mushrooms by the French professor Henri Braconnot in 1811.61 In the 1820’s chitin was also isolated from insects.62 Chitin is an extremely long chain of N-acetyl-D-glucoseamine

    FIGURE 2.
    a) Chitosan full structure
    b) Abbreviated Chitosan structure
    c) Fanciful "crab oligomer" Chitosan structure showing functional claw

    glucoseamine units. Chitin is the most abundant natural fiber next to cellulose and is similar to cellulose in many respects. The most abundant source of chitin is in the shells of shellfish such as crab and shrimp. The worldwide shellfish harvest is estimated to be able to supply 50,000 tons of chitin annually.63 The harvest in the United States alone could produce over 15,000 tons of chitin each year.64

    Chitin has a wide range of uses but that is the subject of another book. Chitosan was discovered in 1859 by Professor C. Rouget.65 It is made by cooking chitin in alkali, much like the process for making natural soaps. After it

    ----------------------------------
    • Waste Water Purification • Stabilizing Oil Spills • Stabilizing Fats in Food Preparation • Antibacterial Protection for Seeds • Flavor Stabilizer • Stabilizes Perishable Fruits/Vegetables • Ion Exchange Media • Bacterial Immobilizer • Cosmetic and Shampoo Additive • Tableting Excipient • Absorbant for Heavy Metal Removal
    Table 5. Industrial Uses of Chitosan 66-75

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    • Absorbs and Binds Fat • Promotes Weight Loss • Reduces LDL Cholesterol • Boosts HDL Cholesterol • Promotes Wound Healing • Antibacterial/Anticandida/Antiviral • Acts as Antacid • Inhibits the Formation of Plaque/Tooth Decay • Helps Control Blood Pressure • Helps Dental Restoration/Recovery • Helps to Speed Bone Repair • Improves Calcium Absorption • Reduces Levels of Uric Acid
    Table 6. Health and Nutrition Uses of Chitosan 60,66,77-107

    is cooked the links of the chitosan chain are made up of glucosamine units. Each glucosamine unit contains a free amino group. These groups can take on a positive charge which gives chitosan its amazing properties. The stucture of chitosan is represented schematically in Figure 2. Research on the uses of chitin and Chitosan flourished in the 1930s and early 1940s but the rise of synthetic fibers, like the rise of synthetic medicines, overshadowed the interest in natural products. Interest in natural products, including chitin and chitosan, gained a resurgence in the 1970s and has continued to expand ever since. Uses of Chit osan Some of Chitosan's major uses—both Industrial and Health and Nutritional—are listed in Tables 5 and 6.

    Water Purification

    Chitosan has been used for about three decades in water purification processes. 67 When chitosan is spread over oil spills it holds the oil mass together making it easier to clean up the spill. Water purification plants throughout the world use chitosan to remove oils, grease, heavy metals, and fine particulate matter that cause turbidity in waste water streams.

    Fat Binding/ Weight Loss

    Like some plant fibers, chitosan is not digestible; therefore it has no caloric value. No matter how much chitosan you ingest, its calorie count remains at

    ------------------------------
    Dietary Fiber % Fat Excreted Dietary Fiber %Fat Excreted Chitosan 50.8 + 21.6 Carrageen 9.6 + 1.9 Kapok 8.3 + 1.1 Sodium Alginate 8.1 + 2.2 Pectin 7.4 + 1.9 Locust Bean 6.0 + 1.8 Guar 6.0 + 1.7 Konjak 5.2 + 0.6 Cellulose 5.1 + 2.1 Karaya 4.9 + 1.5 Acacia 4.6 + 0.9 Furcellaran 4.4 + 0.9 Chitin 4.3 + 1.0 Agar 2.8 + 0.4
    TABLE 7. Effects of Dietary Fibers on Fecal Lipid Excretion 109,110

    fibers, chitosan’s unique properties give it the ability to significantly bind fat, acting like a “fat sponge” in the digestive tract. Table 7 shows a comparison of chitosan and other natural fibers and their ability to inhibit fat absorption. Under optimal conditions, Chitosan can bind an average of 4 to 5 times its weight with all the lipid aggregates tested.60 (NOTE: This assessment was made without the addition of ascorbic acid which potentiates this action even further.77 Studies in Helsinki have shown that individuals taking chitosan lost an average of 8 percent of their body weight in a 4-week period.76 Chitosan has increased oil-holding capacity over other fibers.108 Among the abundant natural fibers, chitosan is unique. This uniqueness is a result of chitosan’s amino groups which make it an acid absorbing (basic) fiber. Most natural fibers are neutral or acidic. Table 7 summarizes the in vivo effects in animals of various fibers on fecal lipid excretion. As can be seen from the results listed, ingestion of chitosan resulted in 5-10 times more fat excretion than any other fiber tested. D-Glucosamine, the building block of chitosan, is not able to increase fecal fat excretion. This is due to the fact that glucosamine is about 97 percent absorbed while chitosan is nonabsorbable. Fats bound to glucosamine would likely be readily absorbed along with the glucosamine. Chitosan, on the other hand, is not absorbed and therefore fats bound to chitosan can not be absorbed.

    Cholesterol Control

    Chitosan has the very unique ability to lower LDL cholesterol (the bad kind) while boosting HDL cholesterol (the good kind).78 Laboratory tests performed on rats showed that “chitosan depresses serum and liver cholesterol levels in cholesterol- fed rats without affecting performance, organ weight or the nature of the feces.”79 Japanese researchers have concluded that Chitosan “appears to be an effective hypocholesterolemic agent.”80 In other words, it can effectively lower blood serum cholesterol levels with no apparent side effects. A study reported in the American Journal of Clinical Nutrition found that Chitosan is as effective in mammals as cholestryramine (a cholesterol lowering drug) in controlling blood serum cholesterol without the deleterious side effects typical of cholestryramine. 81 Chitosan decreased blood cholesterol levels by 66.2 percent.82 It effectively lowered cholesterol absorption more than guar gum or cellulose.83 Laboratory test results indicated that a 7.5% chitosan formula maintained adequate cholesterol levels in rats, despite a dramatic increase in the intake of cholesterol. 84

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    CHEMICAL COMPOSITION AND NUTRITIONAL VALUE
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    Date: June 25, 2005 01:09 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: CHEMICAL COMPOSITION AND NUTRITIONAL VALUE

    CHEMICAL COMPOSITION AND NUTRITIONAL VALUE

    There are at least thirteen known triterpenoid saponins, referred to as ginsenosides in the different ginseng plants. These are thought to be the most important active constituents.4 0 Many other components, thought to be minor, have also been isolated. The composition of each plant varies greatly according to the age, location, species and curing method.41 Some of the plants tend toward stimulating and warming, referred to as yang in Chinese traditional medicine, while others are relaxing and cooling, referred to as yin. The Asian variety has more of a stimulating effect because of its concentration of ginsenosides. The American is thought of as being more cooling and acting as a general body tonic.

    Many people throughout Asia actually prefer the American variety because of its cooling effect.42 Ginseng contains vitamin A, which is necessary for a healthy immune system, essential for mucous membranes, healthy eyes and skin, and to prevent and heal colds, flu, and fevers. It also contains vitamin E, which is essential for a healthy heart and circulatory system. Bcomplex vitamins, thiamin, riboflavin, B12, and niacin are important for maintaining healthy nerves, skin, hair, eyes, liver and muscle tone in the gastrointestinal tract. Ginseng also has calcium, iron, phosphorus, sodium, silicon, potassium, manganese, magnesium, and sulphur.

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    Cultivation and Export
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    Date: June 25, 2005 01:01 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cultivation and Export

    Cultivation and Export

    Ginseng is difficult to cultivate and requires a large capital investment. The plants need shade to thrive and are often grown among forest shade trees or under artificial shade. The Asian countries are not able to keep up with the demand for ginseng because of its popularity. The soil has been cultivated for so many years that some believe the nutrients have been depleted. This has increased the value of the American ginseng. The American variety is found growing wild in cool wooded areas with rich soil in the eastern United States.

    Ginseng is grown commercially in Wisconsin, Michigan and even as far south as northern Florida, Alabama, Louisiana and Oklahoma. Most of the commercial ginseng is grown in Marathon County, Wisconsin and cultivated under artificial shade. Marathon County seems like an ideal place for ginseng to grow as many serious athletes and marathon runners use ginseng to enhance their overall performance. In fact, many Olympic athletes take ginseng routinely. The soil in this area is welldrained acidic soil beneficial for growing ginseng. It is grown using fertilizers, pesticides and other chemicals to ensure adequate production and cultivation. Organically grown plants are available but may be hard to find. Wild ginseng grows in isolated patches in some areas of the country but most sources have been depleted. Some ginseng farmers in Wisconsin have been growing the plants for 90 years. Ninety-five percent of the American grown ginseng is sold to foreign markets, with most of it going to Hong Kong and then into China, Korea and Japan.

    About 45,000 kg. of the dried ginseng root and about the same amount of the wild root is exported annually.13 The American variety sells for about twice as much as the Asian variety because it is thought to be of a higher quality. The Americans import a large quantity of the Asian and Siberian ginseng, which seems ironic. Wild ginseng of any variety is not as common now, because it has been foraged in its wild state and huge quantities exported for large profits. A special license is now required to dig the wild roots.

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    HISTORY
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    Date: June 25, 2005 10:57 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HISTORY

    HISTORY

    Ginkgo has achieved unprecedented popularity within the last decade and has become a familiar household term. Because interest in treating diseases like Alzheimer’s has escalated over the last decade, the biochemical capabilities of ginkgo in regard to brain function have been investigated and are still being researched. Ginkgo is one of those herbs that has become intrinsically connected with notions of herbal elixirs capable of pre s e rving youth and promoting longevity.

    Ginkgo comes from the oldest species of tree in the world dating back some 200 million years. Some ginkgo trees have been known to live well over an average of 1000 or more years. The ginkgo tree is also known as the “maidenhair tree” and would have probably become extinct if the trees had not been cultivated in Far Eastern temple gardens and nurtured by Oriental monks.

    Ginkgo is a deciduous conifer with separate male and female types. It resembles the pau d’arco tree and like pau d’arco, possesses an unusual immunity to insects and diseases. Ginkgo’s remarkable hardiness enabled it to survive the atomic blast at Hiroshima. Because of its unprecedented longevity, ginkgo biloba has sometimes been referred to as a living fossil.

    Ginkgo has been used in China for over 5000 years. The Chinese refer to the fruit of the ginkgo tree as pa-kwo. This fruit is sold in markets throughout China and resembles dried almonds. Ginkgo fruit is pleasant tasting when fresh, but can become quite disagreeable if allowed to get overly ripe. Asians have relied on extracts of the fan-shaped ginkgo leaf since 3,000 B.C. to heal a wide variety of ailments.

    The Chinese have been acquainted with the curative powers of ginkgo for centuries and have typically used the herb for ailments related to aging, such as circulatory disorders, mental confusion and memory loss. In China, ginkgo seeds, called baigou, are considered lung and kidney tonics and are used in conjunction with acupuncture. Ginkgo seeds also help to tonify the urinary system, so they are used in cases of incontinence and excessive urination.1

    Practitioners of Chinese medicine routinely use ginkgo leaves. Ginkgo was introduced into Eu rope in 1730 and was we l l received, not for its medicinal value, but for its ornamental appeal. It is used extensively in landscaping because of its lovely fern-like leaf. It was brought to America in 1784 to the garden of William Hamilton who lived in Pennsylvania.

    Decades passed before the healing properties of ginkgo we re investigated. Consequently, it has been part of the herbal repertoire only since the 1980s. During this time, it became technically feasible to isolate the essential components of ginkgo. Pharmacologically, there are two groups of substances which are significant compounds found in ginkgo: the flavonoids, which give ginkgo its antioxidant action, and the terpenes, which help to inhibit the formation of blood clots. The majority of scientific interest has focused on Ginkgo’s ability to improve the circulation of blood. O ver the past twenty years, scientific testing on the plant has dramatically escalated. Ha rva rd professor Elias J. Core y, Ph . D , synthesized ginkgo’s active ingredient, ginkgolide B, for the first time in the laboratory. Consequently, stepped-up research in this country and in Eu rope resulted. Ginkgo has been the subject of over 300 scientific studies and continues to intrigue scientists. Much modern research has confirmed ancient applications of ginkgo as well as discovered new ones.

    Ginkgolide, the active component of the herb, is what creates most of ginkgo’s biochemical attributes. Exactly how ginkgolide B functions is not yet known. One theory is that the compound somehow interferes with a chemical found in the body called PAF (platelet activating factor). PAF has been implicated in cases of graft rejection, asthma and other immune disorders. PAF antagonists have been identified from a variety of medicinal plants. These compounds help to explain the pharmacological basis of several traditional medicines and provide a valuable new class of therapeutic agents.

    Particular attention has been paid to ginkgo’s powerful actions on the cardiovascular system. Thousands of Europeans use this herb for peripheral circulatory disorders. As a circulation booster, ginkgo has accumulated some impressive credentials. Because proper circulation is vital to each and every body function, virtually all body systems can benefit from ginkgo therapy.

    Ginkgo’s relationship to brain function has also spawned considerable interest. In 1985, Rudolf Weiss said of ginkgo,

    “ Significant improvement in mental states, emotional lability, memory, and the tendency to tire easily, have been reported.”

    Ginkgo is currently planted in groves and used for a number of medicinal purposes. It is harvested in the summer and can be used in extract, tincture or infusion forms. The therapeutic properties of ginkgo seem endless. Continuing re s e a rch promises to further uncover additional health benefits of this remarkable botanical. Ginkgo extracts are among the leading prescription medications in France and Germany. Currently, millions of prescriptions for ginkgo are written by physicians worldwide.

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    YEAST INFECTIONS AND GARLIC
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    Date: June 25, 2005 10:13 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: YEAST INFECTIONS AND GARLIC

    YEAST INFECTIONS AND GARLIC

    Garlic has proven over and over that it is an effective antifungal agent. For anyone suffering from recurring yeast infections, garlic should be added to the diet. Its compounds are ve ry active against candida albicans which causes yeast infections. Some studies h a ve shown that garlic is more potent in treating yeast infections than nystatin, gentian violet and six other reputable antifungal agents.3 6

    Yeast infections plague millions of Americans and can cause conditions such as thrush, vaginal yeast infections and intestinal yeast disorders. Candida albicans has been linked to a wide variety of symptoms including chronic fatigue, depression, infertility and allergies.

    Much of the scientific research done on garlic has centered around its antimicrobial activity, especially against infectious fungi like C. albicans which causes yeast infections. Chicks that were inoculated with the C. albicans organism were cured after ten days of ingesting garlic.37

    A study reported in Mycologia in 1977 concluded that garlic significantly inhibited all isolates of yeast-like fungi that were tested. Once again, it is important that the allicin component of garlic is present in order to receive the antifungal effect. Some research has suggested that raw garlic was not effective against yeast infections, while aged extracts were very good. An added bonus of using garlic to treat yeast infections is that no clinical stains of C. albicans have been known to become resistant to garlic therapy.

    Because high blood sugar is also related to a higher risk of yeast infections, garlic therapy has an additional advantage. Garlic compounds have demonstrated their ability to lower blood glucose levels which would help to decrease one’s risk of developing a yeast infection.

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