Search Term: " Biome "

	Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?	Darrell Miller	12/7/23
	Solaray Multidophilus 12 - A Twelve-Strain Probiotic Blend	Darrell Miller	11/10/22
	Caprylic Acid - What is it and what are its benefits?	Darrell Miller	9/24/22
	Aged garlic is incredibly good for your heart	Darrell Miller	5/3/19
	Follow your gut to digestive health	Darrell Miller	4/30/19
	Food GOLD: Turmeric is just as effective as 14 pharma drugs butsuffers from NONE of the side effects	Darrell Miller	4/23/19
	6 reasons to care about your gut flora	Darrell Miller	4/11/19
	New evidence shows that walnuts optimize the gut microbiome tosuppress colon cancer cell growth	Darrell Miller	4/6/19
	Can Gut Bacteria Affect Your Mental Health?	Darrell Miller	4/2/19
	Natural matcha green tea extract found to effectively kill breastcancer cells	VitaNet, LLC Staff	11/12/18
	Bifidobacterium Lactis: The Bacterium That Could Help You LoseWeight & Fight Inflammation	VitaNet, LLC Staff	10/10/18
	How to keep your microbiome happy	VitaNet, LLC Staff	8/28/18
	Supplemental nutrition found to treat brain injury better than prescriptions, and may even provide some protection against injury	Darrell Miller	7/26/18
	Cannabis extract fights â??incurable formâ?? of Leukemia	Darrell Miller	6/20/18
	Microbiome, Herbal Medicine, and Probiotics Combine to Extend Lifespan	Darrell Miller	6/2/18
	How to care for your gut bacteria when you're taking antibiotics	Darrell Miller	2/7/18
	Did you have a C-section or take antibiotics while pregnant? Give babies probiotics to avoid diseases like asthma, diabetes	Darrell Miller	12/27/17
	Probiotic for Irritable Bowel Syndrome	Darrell Miller	10/4/17
	Are mangos the nutrient filled superfood we need for better health?	Darrell Miller	9/23/17
	Are gut microbes really a panacea, or just overhyped?	Darrell Miller	9/22/17
	Now that's good bacteria	Darrell Miller	9/7/17
	The new science on anxiety and gut health	Darrell Miller	9/1/17
	Health Matters: How Gut Microbes Influence Depression	Darrell Miller	8/29/17
	Healthy gut bacteria improve immunity	Darrell Miller	7/7/17
	Microbiome – Gut health discoveries revealed	Darrell Miller	6/29/17
	Colostrum - Your Way to Super Gut Health	Darrell Miller	6/17/17
	Gut bacteria may help explain benefits of breastfeeding	Darrell Miller	5/15/17
	Could Germs in the Gut Give Rise to Chronic Fatigue Syndrome?	Darrell Miller	5/1/17
	Why anti-inflammatory eating is the next big thing	Darrell Miller	3/2/17
	Stunning scientific discovery finds that gut bacteria control your brain chemistry, altering moods and more	Darrell Miller	2/19/17
	A Gut Makeover for the New Year	Darrell Miller	1/12/17
	Gut bacteria may hold key to treating autoimmune disease	Darrell Miller	12/29/16
	Does Melatonin Decline As We Age?	Darrell Miller	9/22/15
	Chronic Illness and eating healthy	Darrell Miller	11/9/07
	Coenzyme Q10 and Cardiovascular Health.	Darrell Miller	12/13/05
	ST. JOHN’S WORT AND AIDS/HIV	Darrell Miller	7/15/05
	HYPERICIN	Darrell Miller	7/14/05
	PREVIEW	Darrell Miller	6/25/05
	Defeat Depression	Darrell Miller	6/13/05
	Centering Your Heart	Darrell Miller	6/13/05
	Health Movements - Joining mind and body with healthy movement generates harmony	Darrell Miller	6/12/05
	Heart Science - A Five-Tiered Approach to Heart Health ...	Darrell Miller	6/2/05
	COENZYME Q10 - Transforming food into energy	Darrell Miller	6/1/05

Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt Biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592)

Date: November 10, 2022 11:23 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Solaray Multidophilus 12 - A Twelve-Strain Probiotic Blend

Probiotics are live bacteria that are good for your health, especially your digestive system. They can improve your gut health and even boost your immune system. But with so many different probiotics on the market, it can be hard to know which one to choose. That's where our new twelve-strain probiotic blend comes in. This blend contains over 20 billion living organisms, including B. lactis, B. bifidum, B. infantis, B. longum, L. acidophilus, L. brevis, L. bulgaricus, L. paracasei, L. planatarum, L. rhamnosus, L. salivarius and Streptococcus thermophilus—strains that have been shown to be particularly effective in supporting gut health.

But why take a probiotic? Probiotics can help to improve your gut health by restoring the balance of good bacteria in your gut microBiome. They can also help to reduce inflammation and alleviate symptoms of conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Plus, taking a probiotic regularly can help to boost your immune system. So if you're looking for a probiotic that will support your overall health, our twelve-strain probiotic blend is an excellent option.

How the Twelve-Strain Probiotic Blend Works

When you take the twelve-strain probiotic blend, the live bacteria begin to work immediately—restoring balance to your gut microBiome and improving your gut health. The strains in the blend work together synergistically to provide the most effective results possible; for example, Bifidobacterium longum has been shown to increase the production of short-chain fatty acids (SCFAs), while Streptococcus thermophilus has been shown to reduce intestinal permeability (a common cause of inflammation). Together, these strains provide comprehensive support for gut health and immunity.

The Benefits of Taking the Twelve-Strain Probiotic Blend

There are many benefits to taking the twelve-strain probiotic blend on a regular basis. In addition to restoring balance to your gut microBiome and improving your gut health, the blend can also help to:

• Reduce inflammation
• Alleviate symptoms of IBS and IBD
• Boost your immune system
• Reduce the number of colds and other respiratory infections you get
• Protect you from food poisoning
• Reduce cholesterol levels
• Improve skin health
• Reduce anxiety and depression symptoms
• Increase weight loss
• Improve cognitive function

If you're looking for a probiotic that will support your overall health, our new twelve-strain probiotic blend is an excellent option. This potent blend contains over 20 billion live organisms—including Bifidobacterium longum, Streptococcus thermophilus, and other strains that have been shown to be particularly effective in supporting gut health—and it works immediately to restore balance to your gut microBiome and improve your gut health. Plus, the twelve-strain probiotic blend offers numerous other benefits, like reducing inflammation, boosting immunity, reducing anxiety and depression symptoms, and increasing weight loss. So if you're looking for a powerful probiotic that will support your overall health and well-being, our twelve-strain probiotic blend is an excellent option!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6565)

Date: September 24, 2022 10:55 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Caprylic Acid - What is it and what are its benefits?

NOW® Caprylic Acid is a naturally derived nutrient also known as octanoic acid. Caprylic acid is a medium-chain fatty acid (MCT) that is naturally found in coconut and palm kernel oil. Caprylic acid feeds friendly bacteria and fights candida. Candida overgrowth can lead to feelings of fatigue, moodiness, headaches, and digestive issues. Taking caprylic acid can help restore balance in the gut and improve overall health.

What is Caprylic Acid?

Caprylic acid is a type of saturated fatty acid that has antimicrobial properties. It occurs naturally in coconut oil, palm kernel oil, and human breast milk. Caprylic acid is also known as octanoic acid. It gets its name from the Latin word for “egg” because caprylic acid was first isolated from egg white in 1807.

Benefits of Caprylic Acid

Caprylic acid has many potential health benefits. It has been shown to fight candida, which is a type of yeast that can overgrow in the body and lead to fatigue, moodiness, headaches, and digestive issues. Caprylic acid also helps to restore balance in the gut microBiome by killing bad bacteria and promoting the growth of good bacteria. Additionally, caprylic acid has anti-inflammatory properties and can help to improve cognitive function and joint health.

How to Take Caprylic Acid

Caprylic acid is available in SoftGel form. It can also be taken as an oil or added to food or beverages. The recommended dosage depends on the form you are taking as well as your age, health, and other factors.

In Summary:

NOW® Caprylic Acid is a naturally derived nutrient with many potential health benefits. It can help fight candida, restore balance in the gut microBiome, improve cognitive function, and reduce inflammation. Caprylic acid is available in SoftGel form. If you're struggling with Candida or other bacterial overgrowth in the intestinal tract, consider using caprylic acid and take back control of your life.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6463)

Date: May 03, 2019 04:18 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Aged garlic is incredibly good for your heart

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6255)

Date: April 30, 2019 04:02 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Follow your gut to digestive health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6224)

Date: April 23, 2019 01:53 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Food GOLD: Turmeric is just as effective as 14 pharma drugs butsuffers from NONE of the side effects

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6156)

Date: April 11, 2019 08:12 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 6 reasons to care about your gut flora

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6125)

Date: April 06, 2019 09:26 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: New evidence shows that walnuts optimize the gut microBiome tosuppress colon cancer cell growth

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6121)

Date: April 02, 2019 02:06 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Can Gut Bacteria Affect Your Mental Health?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6111)

Date: November 12, 2018 02:51 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Natural matcha green tea extract found to effectively kill breastcancer cells

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5828)

Date: October 10, 2018 03:26 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Bifidobacterium Lactis: The Bacterium That Could Help You LoseWeight & Fight Inflammation

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5780)

Date: August 28, 2018 05:53 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: How to keep your microBiome happy

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5729)

Date: July 26, 2018 08:58 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Supplemental nutrition found to treat brain injury better than prescriptions, and may even provide some protection against injury

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5677)

Date: June 20, 2018 04:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cannabis extract fights â??incurable formâ?? of Leukemia

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5636)

Date: June 02, 2018 05:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: MicroBiome, Herbal Medicine, and Probiotics Combine to Extend Lifespan

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5625)

Date: February 07, 2018 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to care for your gut bacteria when you're taking antibiotics

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5521)

Date: December 27, 2017 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you have a C-section or take antibiotics while pregnant? Give babies probiotics to avoid diseases like asthma, diabetes

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5457)

Date: October 04, 2017 10:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Probiotic for Irritable Bowel Syndrome

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5308)

Date: September 23, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Are mangos the nutrient filled superfood we need for better health?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5273)

Date: September 22, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Are gut microbes really a panacea, or just overhyped?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5270)

Date: September 07, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Now that's good bacteria

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5231)

Date: September 01, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The new science on anxiety and gut health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5202)

Date: August 29, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Health Matters: How Gut Microbes Influence Depression

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5193)

Date: July 07, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Healthy gut bacteria improve immunity

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4938)

Date: June 29, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: MicroBiome – Gut health discoveries revealed

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4905)

Date: June 17, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Colostrum - Your Way to Super Gut Health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4854)

Date: May 15, 2017 06:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gut bacteria may help explain benefits of breastfeeding

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4624)

Date: May 01, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Could Germs in the Gut Give Rise to Chronic Fatigue Syndrome?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4516)

Date: March 02, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why anti-inflammatory eating is the next big thing

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4055)

Date: February 19, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Stunning scientific discovery finds that gut bacteria control your brain chemistry, altering moods and more

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3976)

Date: January 12, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A Gut Makeover for the New Year

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3773)

Date: December 29, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gut bacteria may hold key to treating autoimmune disease

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Date: September 22, 2015 01:00 AM
Author: Darrell Miller
Subject: Does Melatonin Decline As We Age?

Melatonin is a hormone secreted by the pineal glands.  The circadian production of melatonin is tied to the day/night cycle. Light through the retina signals the pineal glands to suppress its production. Lack of light stimulation (at night) results to increased production of melatonin. The increased hormone production at night is associated with a good night’s sleep. According to a study, melatonin significantly reduces sleep latency and increases sleep efficiency. It has thus been used to treat insomnia.

Aging and Insomnia

Insomnia is commonplace among the elderly. As we age, sleep problems which include difficulty in falling asleep and maintaining the sleep are so rampant. This is so because melatonin production declines with age. With age comes the disruption of the circadian rhythms associated with the production of melatonin. To this end, melatonin supplements come handy to the elderly in maintaining a good night’s sleep.

Aging and Alzheimer's Disease

There is more to this hormone than a good night’s sleep and normal aging. There are evidences that melatonin suppresses Alzheimer’s disease. AD is the leading cause of dementia among individuals older than 65 years. Lack of sleep is a common symptom among AD patients and feels bad but sundowning (worsening of symptoms during evening hours) is worse. According to Netherlands Institute of Brain Research, the declining production of melatonin among the elderly not only affects the circadian rhythms but also enhances the development of Alzheimer.

Melatonin as an Antioxidant

Melatonin production starts to decline at age 60. This is the onset of diseases like AD which leads to increased production of free radicals in the brain. According to a review paper written in 2000, there is a lot of pathological changes among AD patients’ autopsied brains as a result of free radical activity. Melatonin carries antioxidant properties which fight the free radicals and protect the brain neurons.

Melatonin Supplements

Melatonin is a powerful hormone. Its function in sustaining optimal human health is crucial. New discoveries are being made on this versatile hormone. The fact that its production starts to decline at 60 only means that you need to use supplements and not fret over the onset of AD or insomnia. It is clear that besides being harmless and natural in treating insomnia, Melatonin is the most effective way of averting deleterious aging effects.

References

www.life-enhancement.com/magazine/article/1025-melatonin-can-reset-your-biological-clock

www.quora.com/Why-do-we-sleep-less-as-we-age

www.Biomedgerontology.oxfordjournals.org/content/56/1/B21.full

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Date: November 09, 2007 12:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Chronic Illness and eating healthy

Chronic illness which exhibits itself as a recurring disease, with lingering and lasting symptoms is a growing pandemic amongst people today. The question is how much of this is due to neglect on the basics of healthy living? Today’s fast paced life style could be a factor for these reoccurring problems. For example, we pride ourselves on keeping five things in the air at the same time; this has caused us to slip from eating three healthy meals per day to drinking a slim fast or popping a diet pill to keep going. Moving away from proper diet and nutrition may be the reason our bodies are breaking down today resulting in chronic illnesses.

Whether you are free from or burdened by illness it is time to take charge of your health! The first thing one can do is basic research. Studies on dietary supplements in scientific and medical research are an ongoing process both in the United States and internationally. If you are interested in finding citations on a particular chronic illness or research that is available I recommend looking at government agencies such as (i) The Office of Dietary Supplements, (ii) The National Institutes of Health (NIH), (iii) The National Agricultural Library (NAL), and (iv) United States Department of agriculture (USDA). It is also possible to obtain research abstracts from different major databases such as MEDLINE for Biomedical related articles and AGRICOLA for botanical and agricultural science. To find these different databases and governmental agencies, search google using the respective agency/database name.

Research shows that stress reduction can help to improve energy levels, improve sleep quality, and reduce high blood pressure. The following are some suggestions for reducing stress:

Reducing stress

Exercise

1. Weight lifting is not just about barbells and muscle-building but about stressing the body as a means for relieving stress.

2. Cardiovascular exercises such as jogging and bicycling.

3. Exercise is helpful by increasing blood flow to the brain, release of hormones, stimulates the nervous system and produces a feeling of well being.

Eating healthy including supplementation

1. Vitamin C or ascorbic acid has the ability to boost the immune system. Vitamin C also helps to produce neurotransmitters by converting L-Tyrosine into dopamine. Along with dopamine, ascorbic acid also synthesizes norepinephrine and serotonin which have been found to be directly related to control anxiety and depression.

2. B-Vitamins are also the important for reducing stress. For example, Niacin (Vitamin B3) helps the body fight stress in three ways, (i) controls blood sugars, (ii) improves blood flow and (iii) regulates the release of energy from carbohydrates.

Stress is a state of bodily or mental tension resulting from factors which are an unavoidable effect of living. Stress has been linked to coronary heart disease, psychosomatic disorders and various other mental and physical problems. Reducing stress is essential and can be done through diet and exercise. Nutritional science studies the relationship between diet and states of health and disease. Nutritional science has found human nutrition is very complex and varies widely and proper nutrition cannot be obtained by simply eating three meals a day because quite simply the average person just does not eat well. If you eat less than five servings of fruits and vegetables daily it is impossible to obtain all of the vitamins and minerals your body needs. In order to seek assurance that you are getting all your body needs I suggest you take a good multiple vitamins which supplies at least 100 percent of the daily value for various vitamins and minerals. It is a good idea however to discuss with your doctor the best choices as he or she knows your history and specific health needs best.

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Vitanet, LLC ®

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Date: December 13, 2005 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coenzyme Q10 and Cardiovascular Health.

CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!

CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.

CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.

As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the Biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”

“The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.

Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.

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Vitanet ®

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Date: July 15, 2005 09:28 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ST. JOHN’S WORT AND AIDS/HIV

ST. JOHN’S WORT AND AIDS/HIV

In 1991, some of the first work focusing on St. John’s wort’s effects on AIDS and the HIV virus began. Science magazine reported on the first study using the isolated hypericin, a key compound in Hypericum.16 Fred Valentine and Howard Hochster, researchers at New York University Medical Center, began one of the first studies looking at how hypericin can help uninfected T-cells from being infected with the AIDS virus in a cell culture. Their focus was on hypericin because it is a virucidal agent, meaning it can precisely target new virus particles and prevent them from infecting other cells.

The only two drugs at that time approved for treating HIV infection—AZT and ddI—work by interfering with the key viral enzyme, reverse transcriptase. Since hypericin works more effectively than many drugs in regards to the reverse transcriptase phase, and since many animal tests have shown that it has low toxicity at therapeutic doses, researchers (including Valentine and Hochster) began these studies largely hoping that not only would hypericin work on its own, but that it would have a sort of synergistic effect when used with either AZT or ddI. 17

Additional studies are pointing to St. John’s wort, and more so, hypericin, as having great potential in treating HIV. Acosta and Fletcher recently detailed the processes in which the human immunodeficiency virus works to infect human cells, and point out that hypericin is at least somewhat effective in inhibiting the four main phases of virus “growth”— binding and entry, reverse transcriptase, transcription and translation, and viral maturation and budding (the researchers note that hypericin is especially effective in binding and entry, the first phase.) This denotes that hypericin could eventually have special importance in completely stifling the development of the growth of any virus, and most importantly, that of the HIV virus.18

Another study assessing the use and attitudes of HIV sufferers concerning the use of more alternative treatments for the virus as opposed to clinical drug therapies showed both an extensive use of unconventional therapies and a very favorable response to using the alternative treatments, which, of course, St. John’s wort was among. “Participants at all sites expressed positive views upon increasing unconventional remedies.”19 The fact is that the world of synthetic medicines has been basically ineffective in not only treating and relieving the symptoms of AIDS, but also in finding a cure for the dreaded disease. Sufferers are giving alternative therapies a try, and the results are very promising.

A 1995 review appearing in Photochemisty-Photobiology treated the photodynamic properties of both hypericin and the structurally related hypocrellins for their anticancer and antiviral properties (especially the anti-human immunodeficiency virus). This article states that the promising anticancer and antiviral results obtained both in vitro and in vivo [in differing studies] have led to intensive investigation into their photo-physical and photochemical processes, especially kinetic studies of their intramolecular proton transfer . . . The Biomedical advances of hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericin.20

Another study published in the September 1994 issue of Photochemistry-Photobiology gave hypericin the upper hand over the hypocrellins in treating HIV. Just one more vote in favor of promoting the use of St. John’s wort, and more specifically, hypericin, for use in treating HIV and in overall clinical medicine.

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Date: July 14, 2005 10:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HYPERICIN

HYPERICIN

One of the reasons St. John’s wort is attracting so much interest is because of one of its compounds, hypericin. The journal Photochemistry-Photobiology recently published a review of hypericins and the structurally related hypocrellins, giving a favorable outline of the various recent breakthroughs in medicine using these two compounds. The review states, Hypocrellins and hypericins, structurally related plant pigments isolated from Hypocrella bambuase and Hypericum respectively, are known photodynamic agents. This review summarizes certain significant advances in the phtotophysics, photochemistry and photobiology of these pigments in the last two years and discusses their prospects as novel therapeutic and diagnostic agents in the future . . . In particular, substantial progress has been made in both anticancer and antiviral applications (especially anti-human immunodeficiency virus). . . . The Biomedical advances of hypocrellins and hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericins.2 The compound hypericin was isolated from St. John’s wort in 1942 and has been used as an anti-depressant and mood stabilizer for emotionally and mentally disturbed people.

Among its many beneficial qualities is that of increasing blood flow to stressed tissue, thereby having a tranquilizing effect. It also reduces the fragility of capillaries and enhances uterine muscle tone because of its ability to increase blood flow.3 It is this compound that is being extensively researched for its possible therapeutic properties for a variety of diseases, mainly depression, AIDS and other viruses, cancer and sleep disorders.

Extensive research has been done, especially recently, to determine exactly how hypericin works in treating these and other disorders. Nearly all the researchers are saying the same thing—that Hypericum (and specifically hypericin) promises significant value to the medical world in overcoming these serious disorders. The following sections discuss the various disorders that are being researched in conjunction with Hypericum/ hypericin therapy.

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Date: June 25, 2005 07:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PREVIEW

PREVIEW

The lifestyles of western cultures have been determined to be major contributing factors in diseases such as heart disease, diabetes and cancer. The most commonly cited factors are inadequate fiber intake, excessive consumption of fats, and a lack of exercise. Educational efforts have resulted in an increase in involvement in various exercise regimines. The consumption of fats, however, continues to increase in spite of the dire warnings that have been publicized. A reduction of fat intake, from an average of 40 percent of the diet to less than 25 percent could have dramatic effects on the health and well-being of the population as a whole. Intake of fiberous foods reduces fat consumption generally through the bulking action of the fibers which leads to a feelings of fullness. Some fibers have an ability to entrap fats in their gelatinous matrix and prevent their absorption. The most effective fiber for preventing fat absorption is chitosan. Chitosan’s fat entrapment properties can be enhanced by combination with ascorbic acid and other dietary ingredients. Fat entrapment by chitosan has been shown in animals and can be readily demonstrated. The use of chitosan in nummerous environmental, agricultual, Biomedical, and health-related areas is well documented. Chitosan has been found to be safe for oral consumption.

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Date: June 13, 2005 01:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Defeat Depression

Defeat Depression

by Cal Orey Energy Times, August 2, 1999

Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery.

More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering.

Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame.

According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life.

The good news: Research shows that diet and lifestyle can lower your risk of depression.

Birth of the Blues

Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes.

Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression.

The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours.

Plan B

Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5).

Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast.

NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions."

Moody Spotlight

Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression.

"SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York.

Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e."

(Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.)

SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant.

For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14).

5-HTP: Another popular supplement to boost mood and relieve depression is hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand.

"One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts.

Herbal Relief

St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that hypericum produced fewer side effects than conventional anti-depressants.

Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers.

"In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner.

Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve."

Amino Acid Help

Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity.

For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety.

The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine.

In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress.

Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.)

Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins.

Depressive Smoking

For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally.

Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99).

"Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers.

If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.

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Vitanet ®

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Date: June 13, 2005 10:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Centering Your Heart

Centering Your Heart by Lisa James Energy Times, January 4, 2004

The romantic view of the human heart conjures up vivid images: The gallant lover, the committed enthusiast, the wise sage. When the romantic philosophy speaks of the heart, it speaks of things that lie at the very center of what it means to be human.

Western medical science, though, views the heart as a Biomechanical pump-marvelously engineered to be sure, but a physical device amenable to surgical and pharmaceutical tinkering.

Between romance and technology lies the Eastern path. Eastern medical traditions, including Traditional Chinese Medicine (TCM) and India's Ayurveda, see the heart as a seat of energy that must be kept in right relationship with the rest of the body.

TCM: Yin, Yang and Qi

The two great polarities of yin and yang are always shifting and rebalancing, according to Chinese philosophy, in our bodies as in everything else. Yin is dark, inward, cold, passive and downward; yang is light, outward, warm, active and upward.

The energy that keeps us alive is called qi, or life force. Organs, including the heart, are seen as places where qi resides. Organs supply and restrain each other's qi, which flows along carefully mapped meridians, or channels. Disease occurs when disturbances in qi interrupt the flow of energy so that an organ experiences either a deficiency or excess of yin/yang.

Circulatory Disturbances

According to Chinese precepts, disturbances in the heart affect the whole body. "The movement of the blood throughout the body, TCM circulation, is managed by multiple organs, which in turn interact with one another. A failure in any one part of this system can result in pathology," says Jonathan Simon, LAc, an acupuncture expert in private practice and at the Mind-Body Digestive Center, in New York.

"If there's a circulation issue, all the organ systems are going to be deprived of the nourishment supplied by the blood. The heart seems to have a dramatic effect on everything else in the body," says Ross Rosen, JD, LAc, CA, MSTOM, Dipl AC & CH (NCCAOM), of The Center for Acupuncture and Herbal Medicine P.A. in Westfield, New Jersey.

Connecting the Dots

While Western medicine probes the heart's physical functioning, TCM searches for energy imbalances by looking for patterns in a person's complaints.

"The wrong approach, in my opinion, is to try to relieve a Western ailment before you have established the proper pattern," Simon notes. "For example, I once had a 20-year-old, slim patient who came to me complaining of hypertension. She had seen several other acupuncturists before she got to my clinic, all of whom had prescribed the number-one formula for hypertension in TCM. When I interviewed her, I discerned a very different pattern from the classic one for hypertension. I gave her the formula associated with her pattern, not her symptom, and she had great relief over the next three weeks. After consultation with her Western physician, she began to cut back on her medication, and is now off of her meds."

TCM emphasizes taking a thorough medical history and using a sophisticated pulse-taking technique called the shen hammer method. Rosen calls pulse "the blueprint of one's health."

Root Causes

As in conventional Western medicine, TCM sees diet as a major culprit in heart disease. "Poor diet will cause problems depending upon on the constitution of the person," explains Simon. "For example, if one eats an excess of greasy and spicy food, that may build up and generate excess heat in the body. That may manifest itself as someone with a quick temper, red face and high blood pressure. On the other hand, a vegetarian who eats only salads may have low energy, a sallow complexion and low blood pressure. I try to tell my patients to keep balance in their diets, but to avoid cold, raw and greasy foods."

TCM also sees unsettled emotions as a source of illness. Stress "creates stagnation in qi and in the blood, eventually," Rosen says. "When stagnation is long or severe, heat starts being produced. We say that heat goes into the blood and steams the body, and heat starts to dry out the vessels. This process winds up turning into atherosclerosis-it kind of vulcanizes the vessel wall. It deprives the vessel of its moisture, which deprives it of its elasticity. Blood pressure starts to increase."

Managing one's emotions and not overworking body or mind is key, says Rosen: "The heart houses the spirit, the shen. When we see people with imbalances in emotion, the spirit starts to become agitated; once the spirit becomes agitated, the whole heart system goes out of balance."

Signs of agitation include insomnia, anxiety and an inability to feel joy, along with chest pain and heart palpitations. TCM uses nutrition, herbs and acupuncture to bring the body back into balance.

Ayurveda: Constitutional Energies

Like TCM, Ayurveda sees health as a matter of balancing the subtle energies that power our bodies. In Ayurveda, these energies exist as three doshas, or basic constitutions:

* Vata is cold, dry, light, clear and astringent. The skin of vata individuals is generally dry, thin, dark and cool, with hair that's curly, dark and coarse. Vatas change their minds readily and crave warmth.

* Pitta is sharp, light, hot, oily and pungent. Pitta people tend to have skin that's soft, fair, warm and freckled, along with fine, fair hair. Quick-witted, pittas hold strong convictions. They prefer coolness, since they tend to perspire profusely.

* Kapha is cold, heavy, oily, slow and soft. Kapha skin is pale, cold and thick, and kapha hair, which is usually brown, is thick and lustrous. Stable and compassionate, kaphas don't like the cold.

Few people are one, pure dosha. Most contain varying levels of vata, pitta and kapha (abbreviated VPK), generally with one predominating.

Doshas Unbalanced

Ayurveda views the heart as "governing emotions and circulating blood," according to Sophia Simon, MS, LAc, of the Karma Healing Center in Newtown, Pennsylvania. In Ayurveda "heart problems arise mainly due to improper diet and stressful lifestyles," which causes a "derangement of vata dosha. This leads to thickening of the arteries, resulting in angio-obstruction."

"Stress reduction is very important in heart disease," says Simon. "Meditation helps a lot with stress reduction, especially simple breathing exercises, yoga, etc." Some of Simon's recommendations have a familiar ring: Don't smoke, do exercise, eat a plant-based, low-fat diet. In addition, she says you should:

* Avoid coffee and other beverages that contain caffeine.

* Be loving and compassionate to all mankind.

* Do things in a casual way. Speak softly. Avoid anger, especially holding anger for a long time.

* Indulge in healthy, whole-hearted laughter.

In addition, Simon notes that garlic is an Ayurvedic herb "most useful for heart problems.

Keep your balance: In the great Eastern healing traditions, it is the key to keeping your heart healthy.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=323)

Date: June 12, 2005 05:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Health Movements - Joining mind and body with healthy movement generates harmony

Health Movements by Sylvia Whitefeather Energy Times, December 6, 2003

Mind/body exercises like yoga (especially the super-popular Bikram variety), tai chi and Pilates aren't just trendy, they're custom made to soothe the rough edges of modern life. So often does today's fast-paced world emphasize the mental and competitive aspects of existence that its inhabitants frequently neglect the necessity of gentle movement for the body. But these exercises are an antidote to the tendency to view the mind and body as separate entities.

Modern science is validating what traditional teachers have always known: The mind dwells in every cell. Joining mind and body with healthy movement generates harmony, lowers your chance of chronic illness and promotes emotional stability.

Yoga

No one knows when yoga first appeared. Historians and archaeologists figure the practice was initiated in India somewhere between 3,000 and 1,500 BCE. But the father of the modern forms of yoga is considered to be a man named Patanjali, who wrote the Yoga Sutra around 200 CE.

The literal translation of the word yoga is "union." As Jennifer Schwamm Willis notes in her book The Joy of Yoga (Marlowe), this practice represents "the union of body, mind and spirit." The purpose of learning the fundamental movements of yoga is to connect with your body, release knots of tension and improve strength and flexibility. In that way, the physical balance during a yoga session translates into inner balance during times of crisis or distress. Schwamm points out that ancient yoga practitioners believed "the aim of yoga is to quiet the fluctuations of the mind, to create stillness in order to hear one's inner voice..."

Yoga is used by many for stress relief. But it has other important uses: In a study presented by Oregon Health & Science University at the American Academy of Neurology meeting in April 2003, yoga was shown to benefit folks with multiple sclerosis. The researchers found that participants who regularly attended yoga class for six months suffered less fatigue and improved their quality of life.

A yoga class generally begins with warm-up postures, moves on to a core group of basic postures, and ends with poses meant to cool you down. An important aspect of yoga is breath work and control. Movement in and out of poses involves carefully orchestrated breath work. Inhalation and exhalation in timed sync with movement lies at the heart of yoga's benefits. Yoga beginners often feel stiff and inflexible. But with gentle, patient, regular practice, greater flexibility, strength and balance can be had. Experts say that a yoga session does not demand struggle; it asks for surrender. If one pose causes discomfort, try another.

Bikram Yoga

One particular form of yoga, Bikram, is hot in terms of both popularity and room temperature: Not only is it one of the biggest trends in the fitness world, this demanding, aerobic take on yoga is conducted in heated rooms designed to maximize muscle relaxation and minimize injury risk. The heat also helps facilitate cleansing and detoxification. It was created by Bikram Choudhury, a four-time Indian yoga champ who founded the Yoga College of India in Beverly Hills, California.

As in other types of yoga, Bikram uses asanas, or poses, handed down through generations of yoga teachers. In this case, though, 26 asanas are done in a prescribed order over a 90-minute period. Everyone, from novice to expert, works out together, the idea being that each individual is working to stretch his or her own limits by becoming stronger, more flexible and less prone to illness.

Bikram yoga stresses the tourniquet effect, in which blood floods through vessels after they've momentarily been squeezed shut. This pressurizing effect is supposed to flush out debris, quickening circulation and releasing stress. The tourniquet effect also helps cleanse the lymphatic system. Proponents say Bikram improves balance, concentration and posture; increases energy; and eases sleep.

Like any other exercise program, Bikram yoga requires diligence: one center says a minimum of 10 classes over 30 days is needed for maximum benefits. And while hydration is important during all fitness routines, consuming adequate water is crucial when you're exercising in a hot room.

Tai Chi

Tai chi (also known as taiji or tai chi ch'uan) consists of a series of fluid movements that build endurance, increase flexibility and balance, and foster alertness of mind and spirit. Tai chi developed around the 13th century as a form of martial arts in China based on the power of flow and grace, rooting and yielding, flexibility and endurance. To the onlooker, a person practicing the movements of tai chi has the quality of someone swimming in air.

This gentle form of movement can be practiced by people of almost all ages and physical conditions. Tai chi does not require special equipment, props or a floor mat. As a non-impact form of exercise, tai chi delivers minimal stress to the joints. Tai chi emphasizes proper body alignment and uses the large muscles in the legs to relieve stress from the hips, back and shoulders. It strengthens joints, increases range of motion and improves circulation of all body fluids. Like many other forms of mind/body exercise, tai chi relieves stress.

Tricia Yu, author of Tai Chi: Mind and Body (DK), has been practicing tai chi for over 30 years. She believes that tai chi not only has benefits as a health exercise, but that it "can have a beneficial effect on your mental and emotional states, as well as help you to feel connected with your surroundings." Yu adds, "Like yoga, tai chi originated in a culture that views the mind and body not as separate but rather as different expressions or states of qi-vital energy or life force."

Current research has validated the health benefits of tai chi. One study found that the knee strength of elderly people practicing tai chi improves significantly (J Gerontol A Biol Med Sci 2003 August; 58:M763-6). Participants in this study, whose average age was 72 years, benefited significantly after five months of tai chi. For the elderly, this extra strength and control translates into fewer falls and injuries.

Tai chi may help immunity. In a study published in the September 2003 issue of Psychosomatic Medicine, researchers reported that elderly folks who participated in a tai chi class for a period of 15 weeks "saw an improvement in factors that suppress shingles [a painful viral condition] increase by 50%." They also showed an increased ability to move throughout the day and a significant improvement in their general health.

Pilates

Joseph Pilates (1880-1968) was a sickly child afflicted with asthma, rickets and rheumatic fever. Determined to recover his health, Pilates studied both Eastern and Western forms of exercise, incorporating moves from gymnastics, yoga and wrestling, along with controlled breathing. With his wife, Clara, Joseph Pilates developed the form of exercise known today as simply Pilates. In the 1920s, Joseph left his native Germany and came to New York City and began teaching his exercise style in dance studios.

Today, Pilates has gained acceptance both as an exercise style for fitness and as a system for physical rehabilitation. Because of its benefits, Pilates is practiced in hospitals, wellness centers, gyms and specialized Pilates studios. It is used by athletes, dancers and anyone looking to increase endurance and improve flexibility, balance and muscle tone.

The basic principle of Pilates focuses on increasing what is called core strength. Core muscle groups include the abdominal, pelvic floor and back muscles. If these muscle groups are strong, then the body is balanced and strong. The Pilates method also encourages flexibility by building long, strong muscles without bulk.

The Stott method is one of the most popular forms of Pilates. This technique combines traditional Pilates exercises with movements updated to conform with modern knowledge about the Biomechanics of the human body. By stabilizing muscles in the pelvis and shoulders, and keeping the spine and pelvis in safe, neutral positions, knowledgeable Pilates instructors minimize the chance of injury during these exercises.

Pilates exercises have been shown to help reduce back pain. Researchers report that "Pilates method can be useful for patients with chronic low back pain and deconditioning" (J Manipulative Physiol Ther 2002 May; 25/4:E3).

According to Ken Endelman, the founder of Balanced Body, maker of Pilates equipment, "Pilates is a full-body exercise. It focuses on flexibility and control, not adding bulk; bulk defeats flexibility. This flexibility is particularly important as we age. Staying flexible is key, and Pilates is good at those types of things."

A Pilates routine can be structured to fit your specific physical needs or goals. Instructors use specially designed equipment along with mat work to improve fitness. The human body was designed to move. Again and again, research shows that exercise maintains health, vitality, longevity, weight and quality of life. If you match your exercise with your physical needs and goals, and your personality, you are more likely to stay with that program whether it is aerobics, walking, Pilates or yoga. For real benefits, physical fitness has to be a lifetime endeavor.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=313)

Date: June 02, 2005 12:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

Heart Science 30 tabs

Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
1) generating energy,
2) decreasing harmful homocysteine levels,
3) fighting oxidized cholesterol,
4) maintaining the heart’s electrical rhythm, and
5) protecting artery and capillary linings.

Energy Generators for An Energetic Organ

Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

Homocysteine Regulators

B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

The Dangers of Oxidized LDL Cholesterol

While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

Cholesterol Fighters

Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

• Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

Artery Lining Protectors

Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

Capillary Strengtheners

Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

Heart Smarts

The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

Source Naturals HEART SCIENCE™

The Five Tiered Approach to Heart Health
Six tablets contain:
Vitamins and Minerals %USRDA
Pro-Vit A (Beta Carotene) 45,000 IU 900%
Vit B1 (Thiamine) 50 mg 3333%
Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
Vit B6 (Pyridoxine HCl) 25 mg 1250%
Coenzyme B6 (Pyridoxal-5-Phosphate)
25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
Vit B12 (Cyanocobalamin) 500 mcg 8333%
Folic Acid 800 mcg 200%
Vit C (Magnesium Ascorbate) 1500 mg 2500%
Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
Copper (Sebacate) 750 mcg 37.5%
Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
Potassium (Citrate) 99 mg *
Selenium (L-Selenomethionine) 200 mcg *
Silicon (From 400 mg of Horsetail Extract) 13mg *
* U.S. RDA not established.
Other Ingredients and Herbs
Coenzyme Q10 (Ubiquinone) 60 mg
L-Carnitine (L-Tartrate) 500 mg
Hawthorn Berry Extract 400 mg
Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
L-Proline 500 mg
L-Lysine (HCl) 500 mg
NAG™ (N-Acetyl Glucosamine) 500 mg
Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
Taurine (Magnesium Taurinate) 500 mg
Horsetail Extract (Yielding 31 mg of Silica) 400 mg
Inositol (Hexanicotinate) 50 mg

Reference:
1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
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COENZYME Q10 - Transforming food into energy

Date: June 01, 2005 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: COENZYME Q10 - Transforming food into energy

Coenzyme Q10

It’s 3:30 p.m. and you feel irritable; you can’t seem to concentrate. You were so busy you skipped lunch. At last you bite into the sandwich that you were ready for 3 hours ago. By the time you have eaten half of it, energy is starting to flow through you. What happened? The answer to that question is both extremely complex and very simple. In essence, your body transformed the food into useable energy. CoQ10 is a crucial component of the primary energy generating cycle that takes place in each of the trillions of cells in our bodies. CoQ10 is essential for human life.

To transform that lunchtime sandwich into useable energy your body essentially has to burn it - just the way a car burns gasoline to drive its engine. This energy generating process takes place in structures called mitochondria - tiny power plants which are within every cell. Inside these energy generating stations, fats, sugars, and amino acids are transformed into ATP, an energy-rich molecule sometimes called the “energy currency” of the body.

Energy Generation Requires Nutrients

The body requires many nutrients in order to perform the complex biochemical processes that convert food into ATP “energy currency.” Some of these nutrients such as the B-vitamins are familiar to us. However, there are many other substances which are essential to this process. Coenzyme Q10 is one of these.

Functions of CoQ10

Several complex metabolic pathways are required in order for the body to transform that lunchtime sandwich into energy that you can feel and use. First glycolysis and the Krebs’ cycle break down large molecules of protein, carbohydrate and fat into smaller components. CoQ10 is a key enzyme in the Electron Transport Chain - the final stage in this extraordinary design. This pathway generates 90% of the ATP needed by the body from the food we eat. ATP provides the “energy currency” for the following crucial metabolic functions: 1) synthesis of cellular components including cholesterol and proteins (formed primarily by the liver), 2) nerve conduction (in the brain and peripheral nerves), and 3) energy for muscular contraction (of the heart and skeletal muscles). The Heart: The heart muscle (myocardium) consumes a tremendous amount of energy. Your heart beats over 100,000 times and pumps 1,000 gallons of blood each day! CoQ10 is necessary for the generation of the energy required by the heart. Numerous scientific studies have demonstrated that supplementation with this nutrient may support normal heart function. Its presence is necessary for cardiac performance during exercise as exemplified by criteria including: blood flow, oxygen utilization, contractility and exercise tolerance. In addition, CoQ10 may play a role in the regulation of blood pressure. The Gums: Since the 1970’s scientists have been researching the effects of CoQ10 on the health of the oral tissues. Although the mechanism of action is not known, research has established that CoQ10 has a profound ability to preserve and maintain the health of the gums. Antioxidant Properties: CoQ10 plays an additional vital role in our metabolism as a protector of lipids in cell membranes. Laboratory studies have also shown that CoQ10 is more efficient than vitamin E, beta carotene or lycopene in safeguarding LDL cholesterol from oxidation by peroxides. This process is important for maintaining the health of our blood vessels.

Energy Insurance

CoQ10 is needed in body tissues where energy production is critical, such as the liver, brain and muscles. Therefore we include CoQ10 in significant potencies in many of our premium formulas, such as Life Force Multiple™, Élan Vitàl™, Heart Science™, Liver Guard™, MenoBalance™, Higher Mind™, MegaMind™ and Wellness Multiple™. We also offer a combination of CoQ10 and Lipoic Acid (30 mg each), CoQ10 Sublingual (30 mg and 60 mg), 30 mg CoQ10 Softgels with Bioperine® and 30 mg CoQ10 NutraSpray™. Our single CoQ10 products are CoQ10 in 15 mg, 30 mg, 75 mg, 100 mg, and Ultra Potency 125 mg caps.

References
1) Folkers et al., BCACQ, Elsevier, 1977
2) Judy et al., BCACQ, Elsevier, 1984.
3) Kamikawa, T. et al., American Journal of Cardiology, Vol. 56, August 1, 1985, p. 247-250.
4) Nohara et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1984.
5) Packer, L., Oxidative Stress and Aging, Birkhauser Verlad, 1995.
6) Stocker, et al., Proceedings of the National Academy of Sciences, Vol. 88, pp 1646-1650, March 1991.
7) Tortora, G. Principles of Human Anatomy, 4th Ed., Harper & Row, New York, 1986, p. 301.
8) Wilkinson and Arnold, Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.
9) Yamagami et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.

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