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  Messages 1-50 from 80 matching the search criteria.
Combine turmeric and black pepper to boost health benefits ofcurcumin Darrell Miller 5/14/19
Shiitake mushrooms are a powerful medicinal superfood Darrell Miller 5/9/19
A species of hawthorn has been found to control abnormally highblood sugar levels Darrell Miller 5/2/19
Women with acute uncomplicated cystitis can benefit from green tea Darrell Miller 4/27/19
Pregnant diabetic women are encouraged to take propolis Darrell Miller 4/24/19
Eat more artichokes! Their leaves contain powerful compounds thatprotect you from diabetes Darrell Miller 4/4/19
Camu camu fruits are rich in an anthocyanin that stops tumors fromgrowing VitaNet, LLC Staff 1/16/19
Study concludes effectiveness of aloe vera for preventing pressureulcers in hospitalized patients Darrell Miller 1/16/19
The science behind curcumin’s healing properties Darrell Miller 1/2/19
One of nature's best medicine, garlic is better at removingparasites in your body than conventional drugs Darrell Miller 11/16/18
Food science: Cinnamon can be used to treat various illnesses VitaNet, LLC Staff 10/19/18
A powerful compound in rosemary protects your brain from damage VitaNet, LLC Staff 9/14/18
Researchers look at the potential of rice bran in treatingcardiovascular disease VitaNet, LLC Staff 8/31/18
Treat your fatty liver disease naturally with a traditional Chinese herbal powder VitaNet, LLC Staff 8/22/18
Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure VitaNet, LLC Staff 8/9/18
Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric) Darrell Miller 7/4/18
Clinical tests reveal that black cumin seed (Nigella Sativa) may treat hypothyroidism Darrell Miller 4/14/17
Through Epigenetics, Curcumin Can Stop Cancer Darrell Miller 8/20/16
Health benefits of Bromelain and its mechanism of fighting inflammation Darrell Miller 4/20/13
How Potassium Iodide Helps Under Active Thyroid Darrell Miller 6/18/12
What Makes a Good Joint Complex or Formula? Darrell Miller 6/29/11
Glucomannon Fiber Darrell Miller 12/19/09
Natural Vitamins under Attack Darrell Miller 6/29/09
Royal Jelly Darrell Miller 6/23/09
Horny Goat Weed Darrell Miller 10/31/08
Hyper-immune Egg Vs Colostrum Darrell Miller 9/23/08
ChewyZymes Darrell Miller 6/5/08
Fight Heart Burn Darrell Miller 4/18/08
Ideal Users For Vitamin K2 Darrell Miller 4/2/08
Beyond Bran Fiber Darrell Miller 12/25/07
How does Sytrinol work? Darrell Miller 2/27/07
Controlling Diabetes with Nutritional Supplements Darrell Miller 12/15/06
Remifemin symptomatic relief, scientifically supported* Darrell Miller 8/26/06
Night Health: A new approach to improving sleep. Darrell Miller 5/12/06
Pomeratrol™ Fact Sheet Darrell Miller 12/19/05
Super Cortisol Support Fact Sheet Darrell Miller 12/8/05
Nattokinase Fact Sheet Darrell Miller 12/8/05
OsteoBoron™ Fact Sheet Darrell Miller 12/8/05
Co-Enzyme B-Complex Fact Sheet Darrell Miller 12/8/05
Psyllium Husk Fiber Fact Sheet Darrell Miller 12/8/05
Butterbur Extract Fact Sheet Darrell Miller 12/8/05
Triphala Fact Sheet Darrell Miller 12/8/05
Carnitine Creatinate Darrell Miller 12/8/05
AHCC® Fact Sheet - from Now Foods. Darrell Miller 12/8/05
VitaBerry Plus+ Fact Sheet Darrell Miller 12/7/05
Enzogenol® Pine Bark Extract Fact Sheet Darrell Miller 12/7/05
TMG Fact Sheet Darrell Miller 12/7/05
Allibiotic CF Fact Sheet Darrell Miller 12/7/05
Astragalus Fact Sheet Darrell Miller 12/7/05
Immune Renew Fact Sheet Darrell Miller 12/7/05




Combine turmeric and black pepper to boost health benefits ofcurcumin
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Date: May 14, 2019 04:08 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Combine turmeric and black pepper to boost health benefits ofcurcumin





Black pepper and turmeric turn out to provide complementary effects, with the piperine in black pepper making it easier for your body to absorb and use the curcumin in turmeric. Piperine helps protect curcumin from inflammatory processes long enough for the body to use it. Curry powder, which contains both turmeric and black pepper, is perhaps the most obvious way to get bother piperine and curcumin in your diet. However, if you truly hate the taste of turmeric, there are supplements available that have both black pepper and turmeric in them.

Key Takeaways:

  • Due to piperine that is contained in pepper that boosts the body’s ability to digest substances, it helps to take turmeric with black pepper.
  • Black pepper and turmeric have lots of similarities when it comes to the health benefits they provide and both are considered aromatic spices.
  • The yellow color of turmeric comes from the compound curcumin which it contains while the black color of black pepper comes from piperine.

"At the same time, it preserves turmeric from inflammatory processes that would normally break down the spice before it could be processed by the digestive system."

Read more: https://www.naturalnews.com/2019-03-31-combine-turmeric-and-black-pepper-to-boost-health-benefits-of-curcumin.html

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Shiitake mushrooms are a powerful medicinal superfood
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Date: May 09, 2019 02:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Shiitake mushrooms are a powerful medicinal superfood





A new study has found that adding fermented shiitake mushroom to rice bran is effective in inhibiting the growth of Salmonella typhimurium. The study was conducted on mouse organs and it was published in the journal BMC Complementary and Alternative Medicine. This formulation has been hailed as a new antimicrobial food-compatible formulation. The study was conducted on murine macrophage cells and in mice. Before this, it was known that the bioactive compounds in rice brans and in shiitake mushrooms have a lot of potential health benefits in mice, cells, and rodents. When the mycelia cells were compared against non-fermented ones, it was found that the bioactive compounds present in the fermented shiitake mushrooms could not be found in the ones that had not fermented. Further findings showed that the pathogen, Salmonella, was inhibited in infected macrophage cells and in organs in the mouse such as the cecum, mesenteric lymph node, spleen, and the liver. Another finding was that there was increased secretion of the bacteria in the feces in mouse. Overall, this findings show that fermented shiitake mushrooms with rice brans can be used as an antibiotic and antimicrobial food.

Key Takeaways:

  • To carry out the study a team of researchers from Korea and the US tried to understand the effect of shiitake mushroom with rice bran on macrophage cells.
  • The component produced in rice plants are bioactive rice brans and hulls while that produced by mushrooms are bioactive polysaccharides and other compounds.
  • When mushroom mycelia that was fermenting with rice bran cells were inspected it was found that they have bioactive compounds that are absent in the non-fermenting mycelia.

"A study published in the journal BMC Complementary and Alternative Medicine found that a formulation of fermented shiitake mushroom with added rice bran can inhibit the growth of Salmonella typhimurium in infected mouse organs."

Read more: https://www.naturalnews.com/2019-04-16-shiitake-mushrooms-are-a-powerful-medicinal-superfood.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6292)


A species of hawthorn has been found to control abnormally highblood sugar levels
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Date: May 02, 2019 02:45 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A species of hawthorn has been found to control abnormally highblood sugar levels





A team of researchers from the Middle East have found that a species of hawthorn, Crete hawthorn, has the ability to lower elevated levels of glucose in the blood. They have published their findings in the journal BMC Complementary and Alternative Medicine. Along with its effects on blood glucose, called its anti-hyperglycemic property, it also has hyperlipidemic properties, that is, the ability to protect the body against high levels of fat such as cholesterol in the blood. They carried out the study using mice that were induced with hyperglycemia through feeding them alloxan. The mice were then divided into two groups, one group receiving Crete hawthorn extracts and the other given a chemical for control. They also used another animal model to understand its hyperlipidemic properties and to investigate whether the plant had antioxidant and antimicrobial properties. The results of the findings were that Crete hawthorn had important antioxidant properties due to its containing phenols and flavonoids. They also found that it had antimicrobial properties because it acted against bacteria such as E. Coli and Staphylococcus aureus, among others.

Key Takeaways:

  • Researchers in the Middle East have discovered that a species of hawthorn, scientific name Crataegus azarolus, can be used to lower elevated levels of glucose in the body.
  • The researchers did not only concentrate on the plant’s anti-hyperglycemic properties, but also on its ability to protect the body against levels of fat that were high.
  • The researchers duing their study found that Crete hawthorn had very high antioxidant properties, especially the ethanol extract from the leaf.

"The mice were then divided into groups, with some receiving an ethanol extract from Crete hawthorn leaves while others were given glibenclamide for positive control."

Read more: https://www.naturalnews.com/2019-03-12-hawthorn-controls-high-blood-sugar-levels.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6243)


Women with acute uncomplicated cystitis can benefit from green tea
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Date: April 27, 2019 10:12 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Women with acute uncomplicated cystitis can benefit from green tea





The health benefits of green tea have long been praised by scientists and health practitioners, and new research actually adds to the current body of knowledge regarding green tea. Recently, it has been found that green tea can aid in the symptoms of acute cystitis. Acute cystitis is categorized as inflammation in the bladder that is prompted by bacterial infection. Green tea has antimicrobial effects, which can help reduce symptoms of acute cystitis with the exception of blood in the urine. Other health benefits of green tea include weight loss, the prevention of cancer, lowering of stroke risk, and improved memory function.

Key Takeaways:

  • Acute cystitis, which affects many women, is a fast onset inflammation of the bladder, usually the result of a bacterial infection.
  • Recently, the publication, Complementary Therapies in Clinical Practice printed data linking cystitis with the use of green tea.
  • Green tea's efficacy against cystitis makes sense, because green tea has catechins that have antimicrobial effect against the E-coli bacteria.

"For this study, researchers from Kerman University of Medical Sciences in Iran carried out a blinded randomized trial to assess the efficacy of green tea as adjunctive therapy to standard antimicrobial treatment in women with acute uncomplicated cystitis."

Read more: https://www.naturalnews.com/2019-03-06-women-with-acute-uncomplicated-cystitis-can-benefit-from-green-tea.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6207)


Pregnant diabetic women are encouraged to take propolis
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Date: April 24, 2019 01:58 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Pregnant diabetic women are encouraged to take propolis





A recent study took pregnant rats who were suffering from gestational diabetes, and they gave them propolis to see if it had a beneficial impact on regulating their glucose levels. The results showed that propolis did, in fact, help regulate blood sugars, and it also helps in several other areas as well. Taking propolis consistently can also help protect you against hypertension during your pregnancy, as well as promote faster wound healing which is extremely important in diabetic patients.

Key Takeaways:

  • Researchers from institutes of higher learning in Malaysia and Nigeria have undertaken study regarding the risks of pregnant women with diabetes.
  • Diabetes, which affects more than 600 million people worldwide, can have deadly effect on the kidneys and the cardiovascular system.
  • Pregnant women with diabetes risk cognitive impairment to their newborns should their sugar levels not be maintained.

"Their study, which was published in BMC Complementary and Alternative Medicine, showed that the superfood propolis not only improves pregnancy outcomes but also placental oxidative stress."

Read more: https://www.naturalnews.com/2019-02-26-diabetic-pregnant-women-should-take-propolis.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6172)


Eat more artichokes! Their leaves contain powerful compounds thatprotect you from diabetes
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Date: April 04, 2019 09:27 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Eat more artichokes! Their leaves contain powerful compounds thatprotect you from diabetes





Diabetes has the harmful potential of damaging the liver, kidneys, and pancreas. Fortunately, research is now showing that the consumption of artichoke leaves can protect your organs from this oncoming threat. This was concluded after a study was performed on rats, giving them a certain amount of alloxan each day which mimicked the effects of artichoke leaves. Once tissue was extracted from their organs, it showed that it was much less damaged than those who were not exposed to the alloxan.

Key Takeaways:

  • The study on artichokes was published in the Journal BMC complementary and alternative medicine. It used alloxan-induced rat models to study the anti-diabetes properties of the plant.
  • Rats were inoculated with alloxan which mimics the effects of diabetes and then were treated with ethanol extracts containing artichokes for about one month.
  • The artichoke extract reduced the level of glucose in the bloodstream by slowing down the conversion of starch into glucose through inhibiting alpha-amylase activity.

"People who are at risk of diabetes and other metabolic disorders would do well to add artichokes (Cynara scolymus) in their diet to lower their chances of getting the disease, according to researchers from the University of Sfax in Tunisia."

Read more: https://www.naturalnews.com/2019-02-04-artichoke-leaves-protect-you-from-diabetes.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6119)


Camu camu fruits are rich in an anthocyanin that stops tumors fromgrowing
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Date: January 16, 2019 08:50 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Camu camu fruits are rich in an anthocyanin that stops tumors fromgrowing





Chrysanthemin is a naturally occurring, odorless, but colorful pigment, normally found in blueberries, acai berries and camu camu fruits. Recently, the pigment made scientific news, which was published in the African Journal of Traditional, Complementary, and Alternative Medicine. Chinese researchers used an array of sophisticated tests to observe how chrysanthemin interacted with and affected prostate cancer cells. The testing and observation revealed that chysanthemin not only inhibited cell growth, but also actively induced cancer cell death. Besides this new and stunning research spotlighting chrysanthemin's potential as a cancer fighter, the substance has other purported health benefits. Data suggests the pigment may be a useful adjunct in the treatment if diabetes and cardiovascular disease. It may also aid cognitive function, skeletal issues and liver function. Study also suggests chrysanthemin can fight inflammation and High fat in the blood.

Key Takeaways:

  • The main goal of the study was to see how chrysanthemin directly impacted cell volume as well as their viability.
  • Chrysanthemin is considered a pigment, and it is part of the anthocyanin family.
  • Studies on animals have shown that chrysanthemin can help decrease the risk of diabetes.

"A study published in the African Journal of Traditional, Complementary and Alternative Medicines revealed that chrysanthemin can stop the development of cancerous tumors."

Read more: https://www.naturalnews.com/2019-01-08-camu-camu-fruits-are-rich-in-an-anthocyanin-that-stop-tumor-progression.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5966)


Study concludes effectiveness of aloe vera for preventing pressureulcers in hospitalized patients
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Date: January 16, 2019 07:55 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study concludes effectiveness of aloe vera for preventing pressureulcers in hospitalized patients





Researchers at Arak University of Medical Science in Iran, performed a study to show that aloe vera works on treating people with pressure ulcers. Many people staying in hospital settings acquire pressure ulcers, or more commonly known as bed sores. Researchers created a treatment and control group. All patients were treated for bed sores and had two treatments a day. One group was treated with aloe vera and the other group was treated with a placebo. They concluded that the patients treated with aloe vera had less swelling, redness, and pain than the other patients.

Key Takeaways:

  • During to the prolonged pressure of staying in a specific position for a long period of time, pressure ulcers or sores develop in patients.
  • The study was conducted in Iran and patients in an orthopedic ward were used to assess the effectiveness of using aloe vera to prevent pressure ulcers.
  • The conclusion of the study was that aloe vera is effective in preventing pressure ulcers due to its effectiveness and being cheaper.

"A new study published in the journal BMC Complementary and Alternative Medicine found a natural way of treating and preventing these ulcers using aloe vera gel."

Read more: https://www.naturalnews.com/2018-12-11-aloe-vera-in-prevents-pressure-ulcers-in-hospitalized-patients.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5964)


The science behind curcumin’s healing properties
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Date: January 02, 2019 05:17 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The science behind curcumin’s healing properties





Nature provides many healing aids, and this spice is among one of the more useful.it has been used for thousands of years to fight and relieve inflammation and has recently been proven effective in preventing oxidation in the circulatory system brought on by smoking and diabetes. It has also proven effective in the tumor reduction treatment in certain cancer lines, which reversing the effects of oxidative stress has shown remarkable progress in the treatment and prevention areas.

Key Takeaways:

  • Turmeric's long history as a culinary spice predates the appearance of Christ by more than 2000 years.
  • Curcumin is the innate part of turmeric which gives the spice it's well-known yellow color.
  • Curcumin has renowned ability as an anti-inflammatory, besides aiding the human heart by keeping cholesterol levels lower.

"Now, two studies published in the African Journal of Traditional, Complementary and Alternative Medicines have confirmed that curcumin also has potent antitumor abilities, in addition to protecting the heart against oxidative stress caused by diabetes and nicotine."

Read more: https://www.naturalnews.com/2018-12-30-the-science-behind-curcumin-healing-peoperties.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5922)


One of nature's best medicine, garlic is better at removingparasites in your body than conventional drugs
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Date: November 16, 2018 02:28 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: One of nature's best medicine, garlic is better at removingparasites in your body than conventional drugs





Garlic is one of those things that has many different use cases. Garlic is very unique and people like it when they are eating certain foods. However, it is now being perceived as a great medicine for people. Conventional drugs are something that do not work to the same level as they used to. There are plenty of people who know that these drugs require a belief in the idea that they do work. Garlic is similar but some people simply like more natural remedies.

Key Takeaways:

  • It is becoming more apparent that garlic has much more uses than initially believed by people.
  • Conventional drugs are useful but there are more natural remedies that are coming into medicine.
  • Understanding how to use things like garlic for heath purposes can be so useful for you in life!

"People have used garlic for thousands of years, whether it’s to add spice to a dish or treat various diseases. If a study in BMC Complementary and Alternative Medicine is to be believed, the well-known herb can also treat a parasitic infection called schistosomiasis."

Read more: https://www.naturalnews.com/2018-11-06-garlic-is-better-at-removing-parasites-than-conventional-drugs.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5838)


Food science: Cinnamon can be used to treat various illnesses
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Date: October 19, 2018 08:52 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Food science: Cinnamon can be used to treat various illnesses





Food science: Cinnamon can be used to treat various illnesses

According to a study in the BMC Complementary and Alternative Medicine journal, cinnamon is a safe and effective anti-parasitic, antioxidant, and antimicrobial substance that can be used to treat many different types of infections. Furthermore, cinnamon can decrease glucose in the blood, making it beneficial to diabetics and pre-diabetics. A study conducted on healthy adults consuming Ceylon cinnamon daily for three consecutive months showed a reduction in both their blood pressure and cholesterol levels. So next time you have a muffin or have a cup of tea, don't hesitate to sprinkle some aromatic and medicinal cinnamon on top.

Key Takeaways:

  • It is crazy to think about how some natural ingredients can really help someone's health.
  • No matter who you are, there is a high chance that you will like a bit of cinnamon!
  • Being able to take care of yourself should be paramount to everything else in life.

"Earlier research suggests that cinnamon offers anti-microbial, anti-parasitic, antioxidant, and blood glucose lowering properties, as well as beneficial cardiovascular effects."

Read more: https://www.naturalnews.com/2018-09-26-food-science-cinnamon-can-be-used-to-treat-various-illnesses.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5795)


A powerful compound in rosemary protects your brain from damage
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Date: September 14, 2018 09:52 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: A powerful compound in rosemary protects your brain from damage





A powerful compound in rosemary protects your brain from damage

Did you know that Rosemary is rich in antioxidant compounds? This is good news given since it is good for stress relief, and a huge amount of people, including children, are currently experiencing stress. People stress about everything from financial issues, employment issues, and the state of our economy. It's not good enough to simply ignore stress. Doing so might result in additional problems like chronic pain, irregular periods, type 2 diabetes, erectile disfunction and much more.

Key Takeaways:

  • Recent research in BMC Complementary and Alternative Medicine suggests that rosemary contains a substance called carnosol that can help preserve brain health.
  • The American Psychological Association has found that Americans are subject to a lot of stress, and that this chronic stress can cause or exacerbate many health problems.
  • Carnosol can measurably help reduce the impact of oxidative stress on the brain.

"The noted survey indicated that almost a third of children had experienced physical stress-related symptoms, such as headaches, stomach troubles, and difficulty sleeping."

Read more: https://www.naturalnews.com/2018-08-12-a-powerful-compound-in-rosemary-protects-your-brain-damage.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5763)


Researchers look at the potential of rice bran in treatingcardiovascular disease
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Date: August 31, 2018 09:53 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Researchers look at the potential of rice bran in treatingcardiovascular disease





Researchers look at the potential of rice bran in treating cardiovascular disease

Malaysian and Chinese researchers recently published a study in BMC Complementary and Alternative Medicine that explores the potential of rice bran to reduce the platelet aggregation that contributes to harmful blood clots in people with atherosclerosis and other cardiovascular diseases. The rice bran policosanol extract used in the study significantly reduced both aggregation induced in response to a mixture of adenosine diphosphate (ADP), arachidonic acid and collagen, as well as adhesion of platelets to surfaces. More research is needed to explore whether this could be beneficial to a variety of cardiac conditions

Key Takeaways:

  • Malaysian and Chinese researchers recently published a study on whether rice bran can reduce harmful blood clots.
  • The researchers found that rice bran made platelets less adhesive and reduced clotting in response to chemically-induced aggregation.
  • Rice bran is a highly nutritious food, rich in Vitamin B and fiber, with potential far beyond its traditional use as animal feed.

"Research has found that rice bran can potentially be used as an alternative treatment for cardiovascular diseases."

Read more: https://www.naturalnews.com/2018-08-29-rice-bran-treating-cardiovascular-disease.html

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Treat your fatty liver disease naturally with a traditional Chinese herbal powder
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Date: August 22, 2018 05:53 PM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Treat your fatty liver disease naturally with a traditional Chinese herbal powder





Treat your fatty liver disease naturally with a traditional Chinese herbal powder

Did you know that an herbal medicine from China called Sinisan can be used in treatment for cadses of non-alcoholic fatty liver disease? Researchers in China studied mice by exposing them to stress until they developed the disease. Then they administered Sinisan to the rodents for nine weeks and saw the symptoms of stress in them diminish. It also showed an increase in body weight and the various levels that are associated with fatty liver disease.

Key Takeaways:

  • To test a Chinese herbal medicine, researchers induced a chronic state of stress in a rodent population.
  • Due to the induced chronic stress, the rodents developed oxidative stress and chronic inflammation of the liver of a non-alcoholic nature.
  • The stressed rodents were administered the medication, with the overall result that they were less stressed had better weight and reduced fatty liver.

"A traditional Chinese herbal medicine called Sinisan can help treat nonalcoholic fatty liver disease (NAFLD), according to a study published in the journal BMC Complementary and Alternative Medicine."

Read more: https://www.naturalnews.com/2018-08-12-treat-your-fatty-liver-disease-naturally-with-a-traditional-chinese-herbal-powder.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5719)


Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure
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Date: August 09, 2018 09:53 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure





Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure

Melanin protects skin from the sun's ultraviolet rays, which can burn the skin, and over time, could reduce its elasticity and cause a person to age prematurely. Suntanning occurs because exposure to sunlight causes the skin to produce more melanin and to darken.The sun's rays make us feel good, and in the short term, make us look good. But our love affair isn't a two-way street. Exposure to sun causes most of the wrinkles and age spots on our faces. Consider this: One woman at age 40 who has protected her skin from the sun actually has the skin of a 30-year-old!

We often associate a glowing complexion with good health, but skin color obtain from being in the sun – or in a tanning booth – actually accelerates the effects of aging and increases your risk for developing skin cancer.

Key Takeaways:

  • One study induced UVB damage in hairless mice to assess whether a flavonoid, hesperidin, would prove protective.
  • Mice in the hesperidin group received 100 milligrams of the flavonoid for every kilogram of body weight, daily.
  • The rodents were irradiated at 48 hour intervals, over a period of 12 weeks, with higher doses of UVB exposure occurring in incremental levels.

"Citrus lovers, rejoice: New research has found that a flavonoid found in citrus can help prevent skin damage brought about by ultraviolet radiation. The study, published in BMC Complementary and Alternative Medicine, has found that hesperidin can protect against photoaging caused by ultraviolet B (UVB) radiation, and prevent wrinkles, skin thickening, and inflammation."

Read more: https://www.naturalnews.com/2018-08-03-hesperidin-a-flavonoid-can-be-used-to-reduce-skin-damage-caused-by-constant-sun-exposure.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5700)


Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)
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Date: July 04, 2018 05:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)





Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)

A recent Kristina University study suggests that fermented turmeric may help protect brain cells from being degraded by inflammation and oxidative stress. The same researchers found that fermented turmeric may also help protect against the impact of the amnesiac compound scopolamine. Researchers subjected scopolamine-treated mice to mazes and inflicted oxidative stress on rat brain cells to test whether fermented turmeric offered any protection. Preliminary results suggest that fermented turmeric could have value as an alternative or complementary treatment for neurodegenerative diseases symptoms.

Key Takeaways:

  • Recent research has shown that fermented turmeric may be beneficial to the brain.
  • Fermented turmeric has displayed properties that aid with memory conditions like Alzheimer's.
  • Turmeric may also protect cells more generally from inflammation and other stress.

"It could serve as an alternative or complementary therapy for age-induced neurodegenerative diseases like Alzheimer’s disease."

Read more: https://www.naturalnews.com/2018-07-02-scientists-study-neuroprotective-effects-of-fermented-curcuma-longa-turmeric.html

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Clinical tests reveal that black cumin seed (Nigella Sativa) may treat hypothyroidism
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Date: April 14, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Clinical tests reveal that black cumin seed (Nigella Sativa) may treat hypothyroidism





It has been discovered that eating some black cumin seeds may help to treat an autoimmune condition called Hashimoto's thyroiditis which is the most common ailment that affects the thyroid. A recent study divided participants into two groups- a group taking the black cumin seeds and a group taking placebo. The study showed that those who took the black cumin seeds showed improvement in lab test compared to those who took placebo. Read this article for more details into this study.

Key Takeaways:

  • -Data showed that patients who received powdered black seeds displayed significant decreases in body mass index (BMI) compared with those who took the placebo pill.
  • -Researchers also highlighted a significant increase in triiodothyronine concentration in patients who received powdered black seeds
  • -The recent results were reflective of findings from two animal studies that examined the compound’s efficacy in improving thyroid function

"Consuming a few grams of powdered Nigella sativa (NS), more commonly known as black cumin seeds, may improve the autoimmune thyroid condition known as Hashimoto’s thyroiditis, according to a study published in the journal BMC Complementary and Alternative Medicine."

Read more: http://www.naturalnews.com/2017-04-11-clinal-tests-reveal-that-black-cumin-seed-may-treat-hypothyroidism.html

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Through Epigenetics, Curcumin Can Stop Cancer
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Date: August 20, 2016 10:28 AM
Author: Darrell Miller
Subject: Through Epigenetics, Curcumin Can Stop Cancer

Epigenetics: In a nutshell, the way we eat turns on and turns off various genes in the body. Depending on your diet, you can turn on cancer preventative genes and turn on genes that promote cancer.

Curcumin is able to tell those apoptosis inducing genes to wake up and end the lives of cancer cells that are defying death. Curcumin can selectively kill cells that have out lived their lifespan with out hurting other normal cells in the body. It reprograms genetically damaged cells to have a normal lifespan.

All of the healing properties of curcumin happen with zero side effects, unlike prescription drugs that your doctor prescribe, that no only have side effects, some of these side effects can be life threatening. Who wants that? Not Me!

If you have cancer, or any disease for that matter, try curcumin as a complementary supplement to what ever you are currently doing to fight it, or take curcumin as a preventative!

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Health benefits of Bromelain and its mechanism of fighting inflammation
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Date: April 20, 2013 09:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Health benefits of Bromelain and its mechanism of fighting inflammation

Bromelain is a blend of enzymes found in the juice and the stems of pineapples and is often used as a health supplement to assist in various disorders and enhance overall health. Here are the health benefits of Bromelain.

Improved Heart health

Bromelain functions as a blood thinner by breaking down the fibrins thus helps prevent blood clotting. It allows blood to move more freely throughout the circulatory system. Thinner blood is linked with lower possibilities of stroke, cardiac arrest and other heart problems.

Improved Breathing conditions

Bromelain is linked to improved breathing conditions that occur as a result of thicker mucus like asthma. It has similar effects on mucus as it has on blood thus making mucus thinner and thus does not clog the bronchial tubes.

Improved Immunity

It serves as an immunity booster and helps certain immunity boosting receptors within the body. As a result it fortifies the immune response by improving the response of body's front-line immune defense called the T-cells.

Improved digestion

If the pancreas is not very active, it may produce insufficient quantities of enzymes, making the food we eat just getting digested partially. Consuming a bromelain supplement might help to cure any resulting digestive complaints like stomach upset, heartburn, diarrhea or indigestion. It is especially effective when used in in conjunction with other enzymes such as amylase and lipase because of its protease functions.

Wound healing

An external application of bromelain might help getting rid of undesirable skin tissues in the third-degree burns. Bromelain could also reduce inflammation due to insect bites and their stings.

Alleviates Sinusitis

Bromelain helps decreasing congestion and the cough that comes with sinusitis. Its anti-microbial attributes may wipe out viruses and bacteria associated with sinus infections.

Relieves varicose veins and Hemorrhoids

Bromelain is used as a complementary medicine in treating chronic venous insufficiency, hemorrhoids and varicose veins.

Enhanced Acid-alkaline balance

Bromelain can help in balancing the acidity and also the alkalinity in the small intestine. The anti-bacterial effects of bromelain helps relieving bacteria-related diarrhea connected with E. coli attacks and inflammatory bowel disease.

Bromelain and Inflammation

While inflammation aids mending the entire body during an injury, excessive swelling can result in health complications and speed up aging. Bromelain is beneficial in treating inflammation. The mechanism of how bromelain fights inflammation involves the inhibition of many bio-chemical responses and reactions that induce inflammation. Treatment with bromelain manages and regulates the activity of various bio-chemical messengers referred to as cytokines in our body. These cytokines are the chemical substances that trigger inflammation. By inhibiting the activity of cytokines, bromelain reduces the impulses that induce an inflammatory reaction.

Bromelain also decreases the deposition of kinins, a by-product of inflammation and also prostaglandins, the hormone-like compounds found through the entire body Thus Bromelain assists fighting the majority of inflammation occurring after having a sports injury or after surgery, or from minor sprains and tendonitis. Certain kinds of arthritis which involve inflammation also benefits from bromelain, particularly in combination with some other typical anti-inflammatory medications.

Do you take bromelain daily?  If not, why not? 

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How Potassium Iodide Helps Under Active Thyroid
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Date: June 18, 2012 08:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Potassium Iodide Helps Under Active Thyroid

Potassium iodide

Potassium iodide is actually an inorganic compound. Also known as KI, its chemical formula, it became the most commercially important iodide compound and was produced around 37,000 tons in 1985. Compared to sodium iodide, KI is less hygroscopic, meaning that it less readily absorbs water. It becomes a precursor to Agl (silver iodide), a useful chemical used in photography. As a medical treatment, it comes in the form of tablet or liquid. In the liquid form, KI is known as SSKI or Thyroshield which is commonly used as preparation the thyroid gland before surgery. In the form of tablet, it is known as thyrosafe or losat and is used to protect thyroid glands from radiation.

Used as disinfectant, KI becomes an antiseptic, like in Betadine. Iodine in Betadine is a common topical disinfectant which is utilized in the hospital operating rooms. It functions to sterilize the skin which will be operated. As water purification, potassium iodide is used to purify water during the emergency situation. Due to the antimicrobial properties, KI will eliminate the illness-causing microorganisms. For the time being, KI is also medical treatments.

Benefits

As medical treatments, KI can be used to help thyroid deficiency. It refers to as hypothyroidism. The thyroid problems are fast becoming. They can cause hair loss, rapid weight gain, anxiety, depression and ongoing fatigue. These problems are usually associated with under active iodine. Hypothyroidism also makes someone older than healthy individual. Even though the only difference from the normal people is only two degrees, this can cause various effects of our body with different symptoms.

The importance of having sufficient iodine is also supported by Michael Tierra in Planet Herbology. She asserts that underactive iodine is major cause to ovarian and breast cancers. Even mild imbalance level of iodine can make the other hormones like progesterone, estrogen and androgen imbalanced.

Potassium iodide has been medically proven to effectively treat patients with under active thyroids. As Schachter Center for the Complementary Medicine reported, it has been used to treat people with chronic Hashimoto's disease or known as thyroiditis.

HyopThyroidism

In terms of under active thyroid or hypothyroidism, potassium iodide can raise up the production of hormones in the thyroid glands. In order to know how KI works to treat iodine deficiency, we can see from the people with these conditions. Commonly, they have weight gain. Even if they have done workouts, the weight will not reduce. Whereas, sufficient iodine is very important to maintain metabolism and prevents the body fat accumulation, as Burton Goldberg writes in Alternative Medicine. That is why KI is required. KI will increase the iodine level so the thyroid will function as normal and the metabolism will also return in usual state.

Therefore, if you have this kind of thyroid problem, then you have to visit your doctor or medical professional. Alternatively, if you have a overweight problem but never do enough exercise, you should not potassium iodide as supplement to lose your weight. KI is not a weight loss supplement, after all. KI has only to be used when you surely have under active thyroid. That will work for this problem.

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What Makes a Good Joint Complex or Formula?
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Date: June 29, 2011 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes a Good Joint Complex or Formula?

Glucosamine/Chondroitin/MSM

Joint pain is a common medical condition that afflicts billions of people worldwide. It is brought on by many different factors, though most of the cases have been tied to arthritis. The joints are especially susceptible to inflammation in old age partly due to the fact that cartilage health becomes impaired as we age. The good news is that certain organic compounds replenish the cartilage content of joints.

Medications and remedies formulated to alleviate joint pain have been extensively studied in the past few decades. Analgesics remain the mainstay of treatment for arthritis to this day, but alternative medicine has also made advances. Proponents of nutritional supplements believe that a good joint formula does not only provide relief from pain but also supplies the proteins necessary for joint health.

Glucosamine

Joint cartilage comprises a group of complex carbohydrates called polysaccharides or oligosaccharides that are attached to proteins. In a process called glycosylation, enzymes add long unbranched chains of carbohydrates to core proteins and form proteoglycans, which nourish the extracellular matrix found in cartilages. In the case of osteoarthritis, the proteoglycan content of joints dwindle with age.

Glucosamine is a precursor to polysaccharides and oligosaccharides. In particular, it is utilized by enzymes to form glycosaminoglycans, which are in turn added to proteoglycans. As a treatment for joint pain, it comes in the form of glucosamine sulfate and glucosamine hydrochloride. It is one of the most promising of all complementary therapies for arthritis as studies have reported positive results.

Chondroitin

Therapeutic remedies that contain glucosamine often come with chondroitin. The sulfated form of chondroitin is a major constituent of proteoglycans, and as such it is generally found in large amounts in joint cartilage in humans. For decades, chondroitin has been used as a therapeutic remedy for arthritis in conjunction with glucosamine as they are believed to enhance the efficacy of each other.

Proponents believe that chondroitin and glucosamine supply the body with healthy quantities of glycosaminoglycans for use by enzymes in the synthesis of proteoglycans. There is consensus in the scientific community that its long term use for the sole purpose of treating osteoarthritis is safe. In addition, recent studies and clinical trials in the past few years have been very encouraging.

MSM

Methylsulfonylmethane, often abbreviated as MSM, is a compound listen as an ingredient in joint formulas. Nutraceutical experts believe that the best joint formula currently available contains all three: glucosamine, chondroitin, and methylsulfonylmethane. While glucosamine and chondroitin provides nutrition for cartilage tissue, MSM counteracts inflammatory mediators that cause joint pain.

Alternative remedies have been the subject of most studies on arthritis in recent years. While analgesics remain commonly used, dietary supplements are becoming increasingly popular among people suffering from joint pain. Glucosamine, chondroitin, and MSM are the most studied of all supplements formulated for joint pain, the reason why health care providers recommend them first.

Grab yourself a joint formula complex and feel the difference!

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Glucomannon Fiber
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Date: December 19, 2009 11:11 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucomannon Fiber

glucomannon powderGlucomannan is derived from the extracted mucilage of the konjac root. This plant is part of the same family as yams, but does not have the calories. Glucomannan is a 100 percent natural form of fiber. The principle use of this herb is as a bulking agent to promote the feeling of fullness.

Glucomannan is a water-soluble polysaccharide. This nutrient is considered to be a dietary fiber. Often, glucomannan is a food additive that is used as both an emulsifier and thickener. Products that contain glucomannan are marketed under a variety of brand names, but are also sold as nutritional supplements for constipation, obesity, high cholesterol, acne vulgaris, and type II diabetes. Glucomannan can be found making up about forty percent by dry weight of the roots of the konjac plant. This nutrient is also a hemicellulose, which can be found in large amounts in wood of conifer plants and in smaller amounts in the wood of dicotyledons.

Glucomannan helps to reduce cholesterol, maintain regularity, and promote intestinal health. The herb also aids in normalizing blood sugar levels, relieving stress on the pancreas, and discouraging blood sugar abnormalities such as hypoglycemia. Glucomannan also absorbs toxic substances that are produced during digestion and elimination. The herb binds toxic materials and eliminates them before they can be absorbed into the bloodstream. Research has determined that glucomannan and lecithin together reduce cholesterol levels. Lecithin is responsible for breaking down fat and cholesterol, and glucomannan eliminates those broken-down particles from the body. This herb expands to about fifty times its original volume when it is taken with a glass of water. glucomannon comes from konjac root

Diabetic patients have reported that they experienced benefits with glucomannan. One study, in which patients were given glucomannan daily for ninety days, found the mean fasting glucose levels to have fallen by 29 percent by the end of the ninety days. At the end of the period, the mean fasting glucose levels fell by 29 percent. Most participants in this study reduced their insulin requirements. Glucomannan may also help cholesterol levels. Animal studies have determined that there is a significant reduction in cholesterol levels when given this herb.

Before supplementing with glucomannan, it is important to speak with your health care provider. In the same sense, you should be sure to tell your health care provider about any complementary and alternative practices that you use. It is important to give them a full picture of what you do to manage your health. This ensures both coordinated and safe health care.

The root of the glucomannan plant is used to provide anorectic, antacid, cholagogue, digestive, nutritive, and purgative properties. The primary nutrients provided by this herb are calcium, iron, magnesium, manganese, niacin, phosphorus, selenium, silicon, sodium, vitamins A, C, B1, and B2, and zinc. Primarily, glucomannan is extremely helpful in treating blood sugar disorders, high cholesterol, constipation, diverticulitis, hemorrhoids, and obesity. Additionally, the herb is very beneficial in dealing with atherosclerosis, high blood pressure, diabetes, gastric problems, hypoglycemia, and pancreatic problems.

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Natural Vitamins under Attack
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Date: June 29, 2009 02:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins under Attack

The value of nutritional supplements in protecting and promoting human health has been intensely debated in recent years throughout the scientific and medical community as well as the national press. Many researchers believe that supplements provide a convenient and effective way to supply the optimal amounts of essential nutrients that are necessary for supporting long-term health, while others argue that there is no proof that supplements provide any real health benefits at all.

A lot of the debate has been published by media that is more interested in selling papers than reporting the truth. Because of this sloppy reporting and distorted information, the public has been unnecessarily alarmed, causing them to lose trust in complementary health care. It is crucial that this false information be addressed before harm that is irreversible is done to an industry that is committed to natural approaches to wellness and a public that is increasingly confused as to where to turn for truthful advice on preventing disease and achieving optimal health. The mixed messages that have been reported in the headlines have confused both health-conscious consumers and medical practitioners, as one day they’re told something is good for them and the next day they’re told it is not.

If there is any consolation to this whole thing, it may be helpful to understand that science never progresses smoothly, as there are always new findings that appear to disprove long-held beliefs. Controversy is necessary for change, as it paves the road that science must travel in order to arrive at the real truth. Unfortunately, bias in the media and conflicts of interest add an unnecessary element to finding the real scientific truth.

When looking at the recent studies that have been negated, there are several explanations that arise for the findings that seem to contradict prevailing scientific evidence. First of all, several long-term dietary intervention trials have recently come about which were developed in the early 1990s before good and bad fats were differentiated. Because of this design, these studies simply assume that all fat is the same, and to reduce fat, one must cut out all kinds of fat. Secondly, it has been proven that there will always be a statistical fluke in a bunch. Therefore, out of 100 clinical studies to investigate a particular effect, probability states that five of these studies, no matter how well they are designed, will show results that are not real.

Thirdly, it is expected that about one fifth of clinical trials that investigate a particular effect will not have the needed number of subjects to produce a result that is statistically significant. This is so because in most clinical trials there is only an 80% probability of finding a real result, which is known as the power of the test. Because of this, there is up to a 20% chance completely missing the mark and failing to find a difference when one actually exists. Finally, some investigations are just bad science, as they are improperly conducted, poorly reported, and inadequately reviewed. Unfortunately, these studies attract a great deal of attention from the media, which has been the case recently.

Natural vitamin supplements can feed the body and help the body fight disease and stay wall. The foods we eat determine what kind of health we will have, if we eat poorly, we will live with poor health. This is why we should consume a multiple vitamin and mineral as well as herbs and food concentrates to help supply our diet with the needed nutrients to sustain and maintain a good healthy lifestyle. Look to your local or internet health food store for vitamins, herbs, and food concentrates.

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Royal Jelly
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Date: June 23, 2009 11:02 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Royal Jelly

Royal jelly is an incredibly rich, creamy, opalescent, white liquid that is synthesized by the worker bees exclusively for the nourishment and cultivation of the queen bee. It is considered the most precious gift of the hive, as it extends the longevity of a bee’s life from six weeks to five years. is incomparable in its ability to enhance both physical and mental performance. Put in a simple manner, royal jelly promotes longevity by helping to maintain health, beauty, and youth.

It is extremely potent, highly nutritional, and very natural. Royal jelly is extremely difficult for scientists to completely breakdown its components or synthesize its compounds. No matter how Royal Jelly is studied, certain components of the substance still seem to mystify even the most brilliant scientists. Because of this, duplicating what is thought to be the exact chemistry of royal jelly does not duplicate its effects in the human body. This means that only honeybees can make royal jelly.

Royal jelly is rich in proteins and B-complex vitamins, especially pantothenic acid, which is often associated with reversing some of the major effects of aging. Although the chemical makeup of royal jelly may vary slightly according to the location it is found in, the United States Department of Agriculture has analyzed one gram of royal jelly and found in to contain vitamin B1, vitamin B2, vitamin B6, niacin, pantothenic acid, biotin, inositol, folic acid, and vitamin C. Royal jelly also contains vital fatty acids, sugars, sterols, phosphorus compounds, and acetylcholine. Acetylcholine is responsible for the proper transmission of nerve impulses and the proper functioning of the endocrine system. A lack of acetylcholine in the body can make us susceptible to a number of nerve disorders such as Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis.

Royal jelly can be purchased in a pure jelly-like material that must be kept frozen or refrigerated. It is also available in capsules, tablets, soft gels, and in honey chewable. Royal jelly is at its ideal best when it is combined with other natural beehive products and complementary botanicals. Because royal jelly spoils very easy, much research has been done on the ability to preserve this key nutrient. One good way to present and preserve royal jelly is within its natural medium of pure honey. By taking freeze-dried varieties of royal jelly, one can also obtain their supplemental dose. A capsulated, freeze-dried variety is an excellent and convenient way to ingest royal jelly.

It is necessary to purchase quality bee products in order to obtain the potent and pure varieties of any type of bee food or by-product. It should be noted that a relatively small percentage of the population can experience a laxative effect from royal jelly or bee pollen. Additionally, allergic reactions can happen. However, they are quite rare. Some of these allergies are due to poor quality pollen, as it has been gathered from commercially sprayed flowers or improperly cleaned, dried, or stored. Anyway taking bee products should begin slowly, in small amounts to be sure that an allergic reaction will not occur.

Natural bee pollen and royal jelly can be found at VitaNet ®, LLC health food store. Always purchase name brands to ensure that you receive a high quality and pure product.



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Vitanet ®, LLC

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Horny Goat Weed
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Date: October 31, 2008 01:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Horny Goat Weed

Item: #4758, 90 Tabs

Product Categories: Hormonal and Vitality Support

Positioning Purpose: The vitality and hormonal support industry is one of the most lucrative in today’s health sector, as evidenced by record sales and an influx of new brands and product offerings. Amazingly, there are still people out there who do not realize that natural alternatives exist. Horny Goat Weed has been a staple in Eastern medicine for centuries, and continues to stand the test of time. Science advancement has helped us better understand its method of action, and we now know that it contains a number of compounds that help support energy, stamina and vitality.*

Product Details: NOW® Horny Goat Weed Extract contains 750 mg of horny goat weed extract (Epimedium grandiflorum, E. brevicorum), standardized to 10% Icariin. For increased support, we’ve added 150 mg of pure Maca Root per serving, another historically used herb that has been shown to support healthy hormones and vitality. Both compounds have a well-documented history of safety and effectiveness. Unlike other products within the hormonal vitality category, this formula can be used by both mean and women.

Nutrient Profile, per serving: Horny Goat Weed (Epimedium grandiflorum), 750 mg Maca Root (Lepidium meyenii), 150 mg

Ideal Users: NOW® Horny Goat Weed is ideal for healthy adults seeking additional hormonal and vitality support. It can be used safely by both men and women.

Recommended Use: As a dietary supplement, suggested use is 1 tablet taken daily, preferably with a meal. Complementary Products: Consider taking NOW® Horny Goat Weed with other NOW products, such as, TestoJack 100™, Tribulus, or ENERGY™

Other Ingredients: Cellulose, Croscarmellose sodium, Stearic acid, silica (vegetable source), magnesium stearate (vegetable source), and vegetable coating.

Supporting Science: Ning H, Xin ZC, Lin G et al. Effects of Icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells. Urology 2006;68:1350-4

Warning: Please consult a healthcare provider prior to use if you have any medical conditions, are taking medications, are pregnant, may become pregnant, or are breastfeeding.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, prevent, treat or cure any disease.

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Hyper-immune Egg Vs Colostrum
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Date: September 23, 2008 03:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hyper-immune Egg Vs Colostrum

When a hen lays her eggs she is virtually an antibody-producing factory, as she passively transfers her antibodies and immunoregulatory factors into the egg in order to protect her offspring. These eggs are made up of a concentrated source of antibodies and helpful immune-supporting biomolecules. However, there are significant differences in the way a cow passes immune protection to a calf and the way a mother hen passes protection to a chick.

A newborn calf will nurse for several months, acquiring immune support over the entire period of time. Since a mother hen cannot nurse her chick, it is essential for the egg to provide all the immune support a chick will need until its own immune system is functioning properly. Because of this, an egg is much more concentrated in antibodies and immunoregulatory molecules than is colostrums. This is an advantage for using hyperimmune egg over supplements that are made from bovine colostrums as an immune system support. It has been found that chickens produce almost twenty times more antibody per unit of weight than cows are able to secret in their milk. Additionally, certain egg antibodies are compared to milk antibodies, and it has been found that egg antibodies seem to be more effective in binding antigens.

In order to produce a hyperimmune egg supplement, the following procedure must be followed. First, eggs are collected from the specially designated chicken flocks after they are specifically stimulated. They are then washed and broken. The yoke of the egg white is then removed and dried to produce a find proteinous powder. There have been various processes developed to minimize the amount of heat damage to antibodies and immunoregualtory factors during the spray-drying procedure. The immune eggs are required to be processed under good manufacturing practices in USDA-inspected and monitored facilities. After processing occurs, the powders are combined with other vitamins, minerals, and possibly other ingredients in order to form a formula that possesses a high nutritive value.

Unlike the conventional methodologies, hyperimmune eggs seems to team up with our immune system instead of boosting or suppressing its function. The immune products in hyperimmune egg are a resource for the body. The body is then able to select those immune elements that it needs in order to up or down-regulate the autoimmune and inflammatory pathways.

Because our immune systems are under constant attack, immune disorders are increasing at an alarming rate. Recent research has found that immune malfunction is an important contributing factor to conditions including heart disease, arthritis, and auto immune disorders. By fine-turning and supporting our immune system in order to prevent disease, we can make one of the best investments possible for our health and longevity.

The potential value of using hyperimmune egg for various health conditions has been shown by new research. Some of the most well-known doctors using alternative and complementary health treatments have found that hyperimmune egg supplements are extremely helpful in reversing a wide array of health problems. As research continues and understanding of how hyperimmune egg works increases, the application of hyperimmune egg can be expected to increase. Impressive properties found in hyperimmune eggs make them an excellent supplement for immune support. When we have a balanced and well-functioning immune system, our lives will be much healthier and happier.



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Buy Immune Advantage at Vitanet ®, LLC

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ChewyZymes
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Date: June 05, 2008 04:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ChewyZymes

Positioning purpose: As the body’s biological workforce, enzymes are fundamental to healthy digestion and metabolism, energy production, and immune system balance. Unfortunately, very few people actually consume an adequate amount of enzymes from their day-to-day modern diets. As the body ages, it produces fewer enzymes with each passing year. Over time, the system-wide effects of insufficient enzymes can manifest in a number of unsuspected ways. Hormone and neurotransmitter production can decline, wounds may not heal as fast, fatigue can become a more regular occurrence, digestion may suffer, and the body may become more susceptible to infection.

Product Description: ChewyZymes™ utilizes National Enzyme’s BioCore system, a broad spectrum digestive enzyme formulation in a natural berry-flavored, vegetarian chewable tablet that is perfectly suitable for both adults and children. It is designed to support improved digestion of meals. Digestive enzymes are essential to the body’s absorption and full use of food. The enzymes in this product are non-GMO. They have been proven in a controlled laboratory study by TNO Nutrition and Foods Research to have efficacy throughout the entire pH range of the digestive system and to not be degraded by acid in the stomach.* Each serving (2 lozenges) is equal to 1 capsule of our popular Optimal Digestive System.

Ingredients:

Ideal Users: Ideal for healthy adults and children who may benefit from additional enzymes in their diet.

Complementary Products: Consider taking this product with NOW® BerryDophilus, Kid Vits, or Chewable C.

Recommended Use: Adults: Chew 2 lozenges before a meal. Children: Chew 1 lozenge before a meal. Supporting Science
Rachman D. Unique Features and Application of Non-Animal Derived Enzymes. Clinical Nutrition Insights 1997;5(10):1-4.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, prevent, treat or cure any disease.

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Fight Heart Burn
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Date: April 18, 2008 11:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Heart Burn

In a search to promote a long and healthy life, a lot of Americans forget about their stomachs, which results in things ranging from simple heartburn to ulcers and even cancer. The effects of alcohol, smoking, and stress added to the rate of infection create the perfect conditions for stomach distress and disease. A combination of four nutrients: zinc, carnosine, licorice extract, and cranberry, work together to protect stomach function from the environment. These nutrients not only relieve distress, but they also support the body’s natural defense mechanisms against inflammation and the changes that can lead to cancer. A fifth nutrient, picrorhiza, protects the mucosa and can now be included as part of a natural gastric health remedy.

The human stomach, with its extreme acidity, provides a primary defense against infection and also helps in the first stages of digestion. A thick coating of protective mucus is steadily secreted by the surface mucous cells in the stomachs lining to continually protect its self from Hydrochloric acid. Almost everyone has experienced some kind of “upset stomach”, which we associate with overindulgence foods and stress. Although these are only thought of as mild annoyances, each episode causes a bit more lasting damage, which eventually results in cellular injury, which in turn causes inflammation. This inflammation then produces free radicals, which go on to create more tissue destruction and eventually damage DNA, thus potentially leading to cancers of the stomach worst case.

Many natural substances have been used around the world for thousands of years to promote stomach health. Modern science is finding that some of these “folk remedies” actually have potent effects on boosting immunity, reducing inflammation, and simply improving physical protection of the stomach lining. Zinc, a micronutrient that has multiple functions in human biology, mainly functions as a defender against free radical damage. It has been found that the more severe the inflammation in people is directly related to lower levels of zinc in individuals.

Zinc also helps to stabilize the membranes of cells that release burst of inflammatory cytokines when they are stimulated by injury or allergy. This mineral is also a well known immune modulator, which can reduce the recurrence rate of certain inflammation-sensitive cancers. There’s no doubt that zinc is a potent anti-inflammatory, and gastroprotective nutrient, but when it is added to amino acid carnosine, these effects can be boosted even further.

Certain fruits, cranberries particularly, are rich in anthocyanins, which have extreme antioxidant abilities. Other compounds that are found in cranberries also prevent bacteria from settling in the urinary tract. A review by nutritional experts found that regular intake of cranberry juice and other dietary products may be an alternative solution for those people who are at risk for H. pylori colonization. It also seems as though cranberries and there extracts can be placed alongside zinc-carnosine as an important component of an effective stomach health regimen.

Licorice extracts have also been shown to help fight stomach infection. Various studies have found that these extracts have potent anti-inflammatory activies, as they reduce cytokine production and increase the protection of the protective stomach mucus. These characteristics, when placed alongside those of zinc-carnosine and cranberry extracts, provide hope that a basis for an alternative therapeutic agent fighting H. pylori can form.

Picrorhiza, which is already used to speed healing in other infections such as hepatitis A, demonstrates unique wound-healing properties, stimulating tissue growth, nerve cell recovery, and blood vessel formation. Even though the multi-armed approach to gastric protection and improved stomach health seems to be complete with zinc-carnosine, cranberry, and licorice extract, picrorhiza extract brings together the infection-fighting, anti-inflammatory, antioxidant, and tissue-healing capabilities of multiple compounds, which all have complementary actions.

If you’re looking for a alternative approach to boost stomach health, the vitamins and herbs listed above are a great starting point. Please do not discontinued prescription medication from your doctor, some cases of stomach issues must be consulted with your doctor before discontinuing use.



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Vitanet ®, LLC

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Ideal Users For Vitamin K2
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Date: April 02, 2008 03:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ideal Users For Vitamin K2

Ideal Users: NOW® Vitamin K2 is ideal for healthy adults looking to support strong, healthy bones, as well as sound cardiovascular health.

Complementary Products: Consider taking this product in combination with NOW® Vitamin D and Calcium and/or Calcium & Magnesium supplements.

Recommended Use: As a dietary supplement, suggested use is 1 Vcap®, to be taken daily with a meal.

Supporting Science

Bolton-Smith C, McMurdo ME, Paterson CR, et al. A two-year randomized controlled trial of vitamin K(1) (phylloquinone) and vitamin D(3) plus calcium on the bone health of older women. J Bone Miner Res. 2007 Jan 23.

Knapen MH, Schurgers LJ, Vermeer C. Vitamin K(2) supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int. 2007 Feb 8.

Additional information: It is important for users to consult their health practitioner before consumption, especially if they are currently taking anti-coagulant drugs (i.e. warfarin, coumadin, heparin), or if you are pregnant/lactating. To avoid the risk of excessive blood thinning, do not take more than the recommended dose.

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Beyond Bran Fiber
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Date: December 25, 2007 08:35 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Beyond Bran Fiber

At one point in time, when you went to the health food store you usually only had choice of wheat bran, which is a good source of the insoluble fiber that helps your digestive system stay on track, or oat bran, which contains the soluble fiber that helps lower cholesterol. Although both of these bran’s are still popular, as they have good reason to be, remaining excellent sources of dietary fiber, these days store shelves are gathering more and more fiber supplements ranging from encapsulated forms to powders and specialized to deal with a variety of health concerns.

Insoluble fiber has the ability to draw water into the intestines, preventing constipation and keeping waste matter from decaying within the body. However, it is the many types of soluble fiber that science has recently started investigating for health benefits. Part of soluble fiber’s value is closely related to its mechanical action, as it forms a thick gel within the digestive track that moves slowly to stop sugar from entering the body too quickly, therefore, helping to keep glucose levels down and carrying some fat and sugar out of the body completely. Additionally, when soluble fibers gel up it helps to reduce blood level cholesterol by trapping bile preventing the bile from doing its action (breaking down fats in the digestive tract so the body can absorb it). Unlike insoluble fiber, soluble fiber undergoes fermentation inside the colon to produce fatty acids that do a little bit of everything, including: helping the body digest food, protecting against polyps, stimulating immunity, increasing mineral absorption, and helping to keep cholesterol and glucose levels in check.

Soluble fiber is getting large amounts of research reviews. One study concluded that people who ate the least fiber are 63% more likely to have high levels of CRP (C-reactive protein). CRP is an inflammation marker that is associated with cardiovascular risk. Another study proved that flax seed improved glucose control. Another fiber source, psyllium, has been shown to bring relief to people with Chron’s disease, an inflammatory intestinal disorder.

Flax seed and psyllium are two of the best known types of soluble fiber available, but there are other types that aren’t as well known. Others including arabinogalactan (AG) have been shown to have a special affinity for natural killer cells. Beta-glucans are another form of fiber that can help boost immunity. Lignans, which are found in flax, have been shown to cause lower breast-cancer rates. Fenugreek is a spice that is rich in galactomannan, a heart-healthy fiber. Some fiber formulations pair up different kinds of fiber with complementary herbs. An example of this is Garcinia cambogia and Gymnema sylvestre, which can be used for glucose control; or astragalus, Echinacea, olive leaf, and shiitake to assist the immune system. Some supplements even provide natural enzymes which help prevent bloating.

It is, of course, important to eat a healthy and well-balanced diet. However, thanks to supplementation that is designed specifically for certain health concerns, it has become much easier to find the additional fiber that is needed by your body, no matter what kind of fiber that is. A large selection of fiber bran supplements can be found at your local or internet health food store.



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How does Sytrinol work?
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Date: February 27, 2007 09:21 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How does Sytrinol work?

Unlike dietary supplements that attempt to block the absorption of cholesterol from the foods we consume, Sytrinol works to balance cholesterol production in the liver naturally. The Sytrinol formula has three different and complementary mechanism of action in the body that deliver heart health benefits without the depletion of CoQ10 common with statin drugs.

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Controlling Diabetes with Nutritional Supplements
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Date: December 15, 2006 04:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Controlling Diabetes with Nutritional Supplements

Controlling Diabetes with Nutritional Supplements

 

Perhaps no other disease is as closely linked to nutrition as diabetes. Not only doe nutrition play a role in its development, nutrition is also one of the disease’s most powerful treatments.

 

Because of this strong and critical connection to nutrition, researchers have carefully studied the use of nutritional supplements in the treatment of the disease. They found that many vitamins, such as vitamin C and the B vitamins, minerals such as chromium, as well as herbs like Gymnema sylvestre, can safely, effectively, and naturally lower blood sugars and help prevent diabetic complications.

 

What is even more important, however, is that these vitamins, minerals, and herbs can be combined together in a scientifically validated diabetic formula to work synergistically. That means their combined effectiveness is even more powerful. Like a group of good friends, these vitamins, minerals, and herbs do their best work when they are all together.

In this issue of Ask the Doctor, we will talk about powerful vitamins, minerals, and herbs combined in a scientifically validated formula that people with diabetes can use every day.

 

But before we get into the specific formula, we need to first talk about diabetes.

 

Q. What exactly is diabetes?

 

A. When we eat, the process of digestion breaks down our food into nutrients. Most of the food we eat is broken down into sugar (also called glucose). The sugar enters the bloodstream for delivery throughout the body and is then called blood sugar.

 

Insulin, a hormone that helps metabolize blood sugar, is made in the pancreas-a long, skinny gland located behind the stomach. Insulin takes blood sugar from the bloodstream and delivers it into the cells that make up the various organs in our body, such as our heart, lungs, and kidneys. The sugar provides energy to the cells to keep our hearts beating, our lungs breathing, and our kidneys excreting.

 

Type 1 diabetes, sometimes called insulin-dependent or juvenile diabetes, most often starts in childhood. In this type of diabetes, the pancreas no longer makes insulin. The sugar stays in the blood instead of going into the cells where it is needed. Because of this, all people with Type 1 diabetes have to take at least one shot of insulin every day just to stay alive.

 

Type 2 diabetes most often starts in adults and is also the most common kind. About 90 to 95 percent of all people with diabetes have Type 2. In Type 2 diabetes, the pancreas is usually producing enough insulin. However, the body does not use it effectively. The condition known as “insulin resistance” occurs when the cells do not respond to (resist) insulin’s attempt to enter with glucose. The pancreas responds by producing more and more insulin. When the cells do not respond, high levels of glucose build up in the blood, leading to Type 2 diabetes. Almost everyone with Type 2 diabetes also is insulin resistant. Because the insulin is left unused, the pancreas thinks it isn’t needed and may eventually stop making it. People with Type 2 diabetes often need to take prescription drugs to lower blood sugar levels if dietary and lifestyle changes are not enough to control the problem.

 

In both types of diabetes, the sugar stays in the bloodstream instead of going into the cells where it is needed and belongs. When blood sugar builds up in the blood, it causes two problems. First, the cells become starved for energy. And, over a period of time, high blood sugar levels can damage the blood vessels, nerves, eyes, and kidneys.

 

Q. What causes diabetes?

 

A. While scientists aren’t exactly sure why Type 1 diabetes happens, they do know the immune system is involved. A healthy immune system protects us from diseases caused by infections, such as colds or the flu, as well as diseases that start in our own cells, such as cancer. For some reasons, in certain people, the immune system becomes confused and begins attacking and destroying the cells in the pancreas that makes insulin.

 

Scientists aren’t exactly sure why Type 2 diabetes happens either; however, they have identified that it occurs most often in certain individuals. About 80 percent of people with type 2 diabetes are overweight, have high blood pressure, and have high cholesterol levels in their blood.

 

Q. What are the symptoms of diabetes?

 

A. Type 1 diabetes develops very quickly. The classic signs of diabetes include:

 

-Frequent urination, because the body is trying to get rid of the excess sugar in the blood

-Intense thirst, because the body needs to replace the fluid lost through the urine

-Increased hunger, because the cells need nutrients

-Weight loss, because without insulin, the body begins to starve

 

The onset of Type 2 diabetes is often very gradual and may develop without any symptoms at all. Sadly, the diagnosis most often is made only after a complication of the disease happens.

 

Q. What are the complications of diabetes?

 

A. The complications of diabetes happen in both types of the disease. All diabetic complications are caused by chronically high blood sugars. The longer your blood sugar levels are elevated, the greater your chances are of having complications.

 

Circulation problems

 

High blood sugar damages blood vessels. When high levels of sugar are continuously in the blood, the blood vessels become thicker and less flexible, causing poor circulation. Poor circulation can impair healing, especially on the feet and lower legs. High blood sugar also causes higher levels of fat in the bloodstream. The fat clogs and narrows the blood vessels. Partial blockages deprive the heart of some necessary nutrients. A complete blockage can result in a heart attack, heart pain (called angina), or stroke.

 

Nerve damage

 

Nerve damage makes it hard for your nerves to send messages to the brain and other parts of the body. It may cause you to lose feeling in parts of your body or have a painful pins-and-needles-like feeling. While nerve damage most often affects the feet and legs, it can also affect other parts of the body.

 

Eye problems

 

Diabetes can damage and weaken the small blood vessels in the retina, the part of the eye that is sensitive to light and helps you see. When the blood vessels are weak, they can leak fluid, which causes swelling in the eye. The swelling blurs your vision. If the eye damage gets worse, your eye attempts to fix this damage by making new blood vessels over the retina. But because these blood vessels are fragile, they can break open easily and bleed into the eye. Scar tissue can then form. This may cause the retina to break away from the back of the eye, which can lead to visual impairment-even blindness.

 

Kidney damage

 

Diabetes can also damage the blood vessels in the kidney so it can’t filter out the body’s waste. High blood pressure is also associated with kidney damage. If you have diabetes and high blood pressure, it is important to keep them both under control as much as possible. The longer blood sugar levels are left uncontrolled, the greater the amount of kidney damage that can occur. If the kidney damage isn’t stopped, some individuals may progress to needing kidney transplants or dialysis machines.

 

All of these complications, however, can almost always be prevented.

 

Q. How can the complications of diabetes be prevented?

 

A. Vitamins, minerals, and herbal supplements can provide powerful tools for preventing serious complications and keeping people with diabetes healthy. The best nutritional supplement contains powerful vitamins, minerals, and herbs in a synergistic formula that can effectively lower blood sugars and provide the specialized nutrients people with diabetes need.

 

Q. Which vitamins, minerals, and herbs should be included in a nutritional supplement for people with diabetes?

 

A. The vitamins, minerals, and herbs in a diabetic formula should work synergistically and be clinically demonstrated to help prevent the known complications of diabetes. To get the best results, it is very important that the right ingredients are in the diabetic formula you buy.

 

Q. How often should I take a diabetic formula supplement?

 

A. Read the label of the diabetic formula you are considering buying. Most quality products need to be taken twice a day. Keep in mind that you will still need to take a high quality multivitamin in addition to the diabetic formula supplement. A diabetic formula is complementary. That means that it is designed to be and addition to your multivitamin routine, not a replacement.

 

Q. Could the diabetic formula lower my blood sugar level too much?

 

A. In general, too low blood sugar levels should not be a problem. A high quality diabetic formula containing synergistic vitamins, minerals and herbs, most often lowers blood sugars to normal levels. However, these vitamins, minerals, and herbs will not excessively lower blood sugar levels that are already normal.

 

Q. Do I need to continue monitoring my blood sugar when taking a diabetic formula supplement?

 

A. Diabetes is a disease that requires active participation from you. You need to be aware of your problem and be in control of it as much as possible. If you use a home glucose monitor to check your blood sugars, you may feel more comfortable by checking your levels more frequently when you first take a diabetic formula supplement. You should always follow the recommendation of your doctor or a licensed health care practitioner regarding how often you should check your blood sugar levels.

 

According to the American Diabetes Association (ADA) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (as well as most licensed health care practitioners), a good blood sugar range for most people with diabetes (before a meal) is from about 70 to 150. An ideal range is 70-120.

 

Taking a nutritional supplement formulated especially for diabetics that contain vitamins, minerals, and herbs that work synergistically in a scientifically valid formula will help you keep your blood sugars right where the ADA and NIDDK recommend.

 

Q. Can’t I just take the diabetic formula supplement and not worry about my diet?

 

A. Unfortunately, you cannot. Successful diabetes management means doing lost of positive things. First, you need to see your licensed health care practitioner often. You need to choose foods wisely and stay active to have a positive influence on your blood sugar levels and your health. And, taking a diabetic formula supplement every day can really help. However, the diabetic formula supplement is meant to be an addition to your healthy diet, not a substitute.

 

Conclusion

 

Having diabetes might make you feel overwhelmed. Restrictions on what you may and may not eat might make you feel deprived and unfairly burdened. The possibility of disease complications may make you feel anxious and scared-even angry. It is only natural to ask “Why me?” Taking control of your diabetes, instead of letting it control you, can help with these feelings. Eating wisely and exercising every day are two important ways to improve your health. And, taking a nutritional supplement formulated specifically for people with diabetes every day can give you the critical control you need to direct your health for years to come. Many healthy years to come.

 

 

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Remifemin symptomatic relief, scientifically supported*
TopPreviousNext

Date: August 26, 2006 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Remifemin symptomatic relief, scientifically supported*

Remifemin

 

Symptomatic Relief, Scientifically Supported*

 

The only RemiSure black cohosh

 

Unique to Remifemin® - Exclusive standardized isopropanolic black cohosh extract, subject of over 90 scientific papers.

Proven Effective – The most clinically studies natural intervention for menopausal symptoms with over 40 years of use worldwide*

 

  • Relief from hot flashes, night sweats, mood swings, irritability, and related occasional sleeplessness*
  • Particularly in women in early stages of menopause*

 

Safe – Completely hormone free

 

  • Works naturally without plant-based estrogens that can affect breast and uterine cell growth
  • Can be used safely by women with a history of breast cancer who cannot take estrogen

 

Efficacy

STUDY DESIGN

BENEFITS

DOSAGE

REFERENCE

1. Twelve-week, randomized, multicenter, double-blind clinical trial comparing the efficacy and tolerability of Remifemin® in the treatment of climacteric complaints compared with placebo.  The primary efficacy measure was the change from baseline on the Menopause rating Scale 1.

·          Remifemin® effectively relieved menopausal symptoms, particularly in women in the early stages of menopause*

·          Most significant reduction was in hot flash occurrence*

·          Other symptoms resulting in significant reduction include: psyche (irritability and memory), and atrophy (vaginal dryness)*

·          No significant adverse effects reported

40mg qd

Osmers R, et al. Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms.  Obstet Gynecol. 2005 May; 105(5):1074-83.

2. A review of 29 randomized controlled trials of complementary and alternative therapies for menopausal symptoms.

·          Black cohosh is one of the only herbal remedies shown to be effective for menopausal symptoms, especially hot flashes*

 

Kronenberg. F. Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med. 2002 Nov 19;137(10:805-13.

3. Four-week, pilot study, open clinical trial of menopausal women with hot flashes, including women with a history of breast cancer.

·          Remifemin® reduced mean daily hot flash frequency by 50% after 4 weeks*

·          Overall, participants reported less trouble with sleeping, less fatigue, and fewer night sweats* 

·          No participants stopped therapy because of adverse effects

40mg qd

Pockaj BA, et al. Pilot evaluation of black cohosh for the treatment of hot flashes in women.  Cancer Invest. 2004;22(4):515-21

4. Double-blind study involving the use of Remifemin® in women ages 43 to 60 with menopausal complaints lasting 6 months.

·          Majority of woman saw a 70% reduction of physical and emotional symptoms after 12 weeks, including hot flashes, night sweats, mood swings, and irritability*

·          Significant improvement was noted after 4 weeks use*

·          Remifemin® works safely and effectively to treat menopause symptoms without affecting hormone levels or vaginal cytology (pap smear)*

40mg qd

Liske J, et al. Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizome): a 6-month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med. 2002 Mar; 11(2): 163-74

5. Double-blind, 6 month study in hysterectomized women under 40 with at least one ovary.

·          As effective as estriol, conjugated estrogens, or hormone combinations at decreasing physical menopausal symptoms at 4, 8, 12, and 24 weeks*

4mg dry extract bid (equivalent to 2 tablets Remifemin® bid

Lehmann-Willebrock E, Riedel HH. Clinical and endocrinologic studies of the treatment of ovarian insufficiency manifestations following hysterectomy with intact adnexa. Zentralbl Gynakol. 1988; 110(10):611-8

 

6. Women aged 45 to 58 with menopausal complaints were studied in a double-blind, 12 week, placebo-controlled trial.

·          Remifemin® decreased physical symptoms of menopause by approximately 60% (Kupperman menopausal indeed)*

·          Daily hot flashes decreased by 86% in the Remifemin® group(from 4.9 to 0.7 per day)*

·          Emotional complaints were also dramatically reduced*

4mg dry extract bid (equivalent to 2 tablets Remifemin® bid

Stoll W. Phytopharmacon influences atrophic vaginal epithelium: Double Blind study – Cimicifuga vs. estrogenic substances. 1987.

 

Safety

STUDY DESIGN

BENEFITS

DOSAGE

REFERENCE

7. in vitro, MCF-7 cell culture model to determine estrogen-agopnist and antagonist activity of commercially available herbal menopause preparations containing red clover, soy black cohosh, or a combination of herbs.

·          Remifemin® had no effect on estrogen-sensitive cells in vitro.

·          Results suggest safety for women with a history of breast cancer who cannot take estrogen.

In Vitro(10^3-10^5 dilutions)

Bodinet C, Freudenstein J. Influence of marketed herbal menopause preparations on MCF-7 cell proliferation.  Menopause. 2004 May-Jun;11(3):281-9.

8. Six-week, in vivo investigation of Remifemin®’s ability to stimulate estrogen-receptor positive cells in an animal model

·          No estrogen stimulating effects were found.

·          Prolactin, follicle-stimulating hormone, and luteinizing hormone levels were unchanged.

0.714m 7.14 or 71.4mg/kg/day

Freudenstein J, et al. Lack of promotion of estrogen-dependent mammary gland tumors in vivo by an isopropanolic Cimicifuga racemosa extract. Cancer Res. 2002 Jun 15;62(12):3448-52.

 

 

 

9. Comprehensive review examining all published literature pertaining to pre-clinical and clinical safety of various forms of Cimicifuga racemosa, as well as FDA and World Health Organization (WHO) adverse event reporting systems, monographs, compendia, internal unpublished data from a major manufacturer, foreign literature, and historical, anecdotal report.

·          Uncontrolled reports, postmarketing surveillance, and human clinical trials of more than 2,800 patients demonstrate a low incidence of adverse events (5.4%).

·          Of the reported adverse events, 97% were minor and did not result in discontinuation of symptoms, and the only severe events were not attributed to Cimicifuga treatemtn.

·          Confirms the safety of specific Cimicifuga extracts, particularly isopropanolic preparations (Remifemin®), for use in women experiencing menopausal symptoms and as a safe alternative for women in whom estrogen therapy is contraindicated *.

Various

Low Dog T, et al. Critical evaluation of the safety of Cimicifuga racemosa in menopause symptom relief. Menopause: Journal of the North American Menopause society. 2003;10(4):299-313.

 

Relevant Reports and Guidelines

ORGANIZATION

PUBLICATION

EXCERPT OF KEY CONTENT

American Botanical Council

The ABC Clinical Guide to Herbs including a black cohosh monograph issues September 2002

“Of 10 clinical studies, including a total of 1,371 participants, nine of these studies demonstrated positive effects for menopausal symptoms.  Numerous clinical trials with varied methods and designs have been conducted on the standardized isopropanolic/ethanolic extract of black cohosh root, Remifemin®, from 1981 to the present.”

National Institute of Health

Questions and Answers About Black Cohosh and the Symptoms of Menopause issued October 2002

“Other preparations of black cohosh have been less well studied than Remifemin® …black cohosh is used primarily for hot flashes and other menopausal symptoms.  A number of studies using various designs have been conducted to determine whether black cohosh affects the menopausal symptoms… To provide more definitive evidence on the effects of black cohosh on menopausal symptoms, NCCAM is funding a 12-month, randomized placebo controlled study to determine whether treatment with black cohosh is effective in reducing the frequency and intensity of menopausal hot flashes.”

The North American Menopause Society

Alternatives to Hormone Replacement Therapy: Suggestions for the North American Menopause Siciety issued July 2002

Reseach suggests that mild hot flashes can be relieved by consuming a serving of soy foods daily or taking a supplement of black cohosh.”

 

Responding to the need for alternative menopausal symptom relief*

 

Natural, Safe alternative to HRT for menopausal symptoms*

 

  • Remifemin black cohosh was as effective as HRT for menopausal symptoms*

 

Superior Manufacturing Quality

 

  • Prepared according to Good Manufacturing Practice (GMPs) which ensure delivery of a product with the highest quality and consistency
  • Convenient dosing – one 20mg tablet twice a day (one in the MORNING, one in the EVENING)
  • 100% RemiSure black cohosh – not a combination of herbs

 

VitaNet Recommends Remifemin

 

  1. Remifemin unique standardized isopropanolic extract is the most widely studied and clinically tested natural alternative treatment for relief of menopausal symptoms.
  2. Remifemin black cohosh proven effective in reducing menopause and peri-menopause symptoms, including hot flashes, right sweats, mood swings, and irritability without estrogenic effects.
  3. Used safely by millions of patients worldwide for over 40 years.  Remifemin has been proven effective and is the most clinically studied natural intervention of menopause.
  4. Remifemin doesn’t have the side effects that are experienced with hormonal drugs prescribed for the relief of menopausal symptoms.

 

Lit source: Enzymatic therapy.

*this statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treate, cure, or prevent any disease.



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Night Health: A new approach to improving sleep.
TopPreviousNext

Date: May 12, 2006 05:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Night Health: A new approach to improving sleep.

Our night health, including the quality of our sleep and dreams, may be the most critical overlooked factor contributing to both emotional and physical illness in modern times. For millions, night is a time of growing frustration and deepening struggle with insomnia as well as compromised and insufficient sleep. Mounting data has confirmed that sleep problems are strongly associated with virtually all major illnesses ranging from cardiovascular disease to diabetes, infections and cancer, and obesity to depression.

Night health refers to a new approach to sleep and dreams that integrates complementary and alternative medicine with effective conventional perspectives. It is essentially a comprehensive body-mind approach to sleep. The first in a series of articles introducing the concept of night health, this article begins with a closer look at the limitations of the simulated sleep offered by sleeping pills. It then examines the basic alternative of supplemented sleep: the place of natural sleep-supporting supplements. Finally, it offers suggestions for increasing the utilization of such alternatives by supplementing supplements with essential information, education and guidance offered by a new and unique software program and the first book about integrative sleep health.

Simulated Sleep

As the public becomes increasingly aware of the health ramifications of sleep disturbances, more and more people are turning to sleeping pills. In fact, according to the IMS Health research, about 42 million prescriptions for sleeping pills were filled last year in the U.S. This represents a nearly 60 percent increase over the past five years alone. Some projections anticipate that the current $2.7 billion in annual sleeping pill sales will more than triple by 2010.

But instead of solving the problem, sleeping pills often make sleep problems worse. Sleeping pills commonly result in dependence. They can alter normal sleep architecture, cause amnesia and residual daytime “hangovers,” and they often result in rebound insomnias when discontinued. Some sleep specialists argue that sleeping pill use is further associated with significant increases in mortality. Given the sense of desperation that can accompany insomnia, even such very serious concerns have not prevented sales of sleeping pills from skyrocketing in recent years.

We are currently witnessing an unprecedented advertising campaign on the part of the pharmaceutical industry designed to convince the public that sleep medications are indeed a safe and effective strategy for addressing sleep problems. Despite clever and seductive advertising, however, it remains highly questionable whether sleeping pills can truly offer us sleep. I believe it is more accurate to say that they result in a kind of artificial or simulated sleep. Compared to natural slumber, sleeping pills cause a chemical knockout. Unfortunately, so many people have slept poorly for so long, they have forgotten what it is like to experience truly restorative, deep and refreshing natural slumber. Instead, many people now hold a naïve, limited sense of healthful sleep, confusing it with being knocked out. And sleeping pills satisfy that very naïve notion of sleep.

Supplementing sleep

Rather than artificially simulating sleep with chemical knockouts, sleep-promoting supplements such as melatonin, valerian, and other botanicals support that body’s own sleep-facilitating mechanisms more naturally. Such products work in greater harmony with nature and, unlike conventional drugs, they do not stimulate sleep, they supplement sleep. I think of natural supplements inviting us to sleep. The very potency of many natural products lies in their very gentleness, which works cooperatively with both body and mind to induce healthful sleep.

I believe that the potential benefits and markets for such supplements remain largely untapped. Consumers’ expectations that sleep aids should knock them out rather than gently assist them in letting go into sleep must be addressed through targeted education and information campaigns. Consumers also need to learn how to use alternative sleep supplements in the context of a healthy sleep lifestyle or positive night health.

Supplementing supplements

As helpful as they can be in promoting night health, sleep supplements alone will not do the trick. In fact, I believe many people get discouraged and discount the potentially positive benefits of sleep supplements after using them without proper guidance and understanding. Sleep supplements work best when they are geared to work synergistically as a part of a larger night health promotion program.

The availability of a wide range of over-the-counter health supplements offers an important freedom in healthcare choices. But with increased freedom comes increased responsibility. Consumers need to become significantly more informed. Particularly with regard to night health, such supplements need to be personalized and prescriptive. When it comes to sleep health, one size does not fit all. Whether we choose melatonin or valerian or a specific blend depends upon who we are and exactly what we need. By prescriptive I do not mean ordered by a physician, but specifically tailored to the needs of the individual.

Because of a significant shortage of health care professionals knowledgeable about sleep and the alarming trend towards increased use of sleeping pills, I have assisted in the development of a unique software program that provides sleep solutions that are both personalized and prescriptive. After more than a decade in development, the sleep advisor—an expert software system that thoroughly evaluates and provides personalized comprehensive recommendations for improving sleep—is now available.

More recently, I completed the first truly integrative book on night health. Healing night: the science and spirit of sleeping, dreaming, and awakening offers a new, comprehensive perspective on night health that complements the sleep advisors high pragmatic approach. Together, healing night and the sleep advisor offers essential supplements to sleep supplements.

Rubin R Naiman is a psychologist and clinical assistant professor of medicine at the university of Arizona’s health sciences center. He is also the sleep and dream specialist for dr. Andrew weil;s world renowned program in integrative medicine. Currently he serves as the sleep specialist at Miraval Resort, and is in private practice in Tuscon, AZ.

The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Rubin R. Naiman, PhD
Integrative Sleep and Dream Psychology
Clinical Assistant Professor of Medicine
Program in Integrative Medicine
University of Arizona
Sleep and Dream Specialist
Miraval Resort
Tucson, Arizona
520-770-1003
rrnaiman@cox.net
www.drnaiman.com
www.thesleepadvisor.com



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Pomeratrol™ Fact Sheet
TopPreviousNext

Date: December 19, 2005 09:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pomeratrol™ Fact Sheet

Pomeratrol™ Fact Sheet

Neil E. Levin, CCN, DANLA 9/28/04

USER: Those needing antioxidant protection; People with a family history of cell growth abnormalities; Anyone concerned with aging

KEY INGREDIENT(S): Pomegranate fruit standardized extract 200 mg. (Punica granatum) containing 80% total polyphenols, including 40% Ellagic acid, Resveratrol (100% trans-resveratrol) 20 mg. from a blend of Japanese knotweed root extract (Polygonum cuspidatum) and grape skin extract (Vitis vinifera)

POTENTIAL BENEFITS: Ellagic acid is a polyphenol compound found in raspberries, strawberries, pomegranates, and other fruit. It has been shown to normalize cell death of abnormal cells, a process called apoptosis. This enhances the body’s cell growth control system by providing an important plant substance. It may bind to DNA to prevent damage to this all-important genetic material. This is a key step in preventing cell damage that leads to signs of aging.

The American Cancer Society says that research in animal and laboratory models has found that ellagic acid inhibits the abnormal growth of certain cells. Research at Ohio State University indicates that berries typically contain a few milligrams per ounce of ellagic acid, the actual level varying quite a bit from variables such as species, variety and growing conditions.

Resveratrol is an antioxidant compound that is a phytoestrogen, or plant estrogen, which is protective of hormone-mediated cells in the body. Resveratrol is a potent antioxidant if stabilized. If not stable, it may quickly metabolize out of the body. This compound is believed responsible for some of the beneficial effects of moderate red wine drinking on the cardiovascular system. Resveratrol is also considered to be beneficial to smokers’ lung tissue if it is stabilized to last long enough in the system to be transported there. Resveratrol is also an inhibitor of the COX-2 inflammatory enzyme and encourages cell death (apoptosis) of abnormally growing cells. In insect experiments resveratrol even repaired DNA, leading to a longer life for healthy cells even as it helped get rid of unhealthy cells. Again, this ability to protect cells and help the body rid itself of abnormal cells is a key factor in preventing signs of aging. One liter of red wine contains between 1.5 and 3 mg. of resveratrol.

OTHER IMPORTANT ISSUES: Resveratrol is a difficult substance to stabilize. Because of the difference between resveratrol produced in the oxygen-poor environment in red wine and the form of resveratrol in unstabilized supplements, it has long been thought that resveratrol supplements were not very effective in comparison with wine. Knowing the importance of how a resveratrol supplement is metabolized, Now’s scientific staff has recently developed a special technique of stabilizing this compound in order to have an antioxidant effect closer to drinking a good glass of wine. While both trans and cis forms of resveratrol are naturally occurring, most of the recorded health benefits are attributed to the trans form. Now’s Pomeratrol provides trans-resveratrol.

DOSE: One capsule per day. Resveratrol has been used safely in studies at doses equivalent to 500 mg./day.

COMPLEMENTARY PRODUCTS: Other antioxidants and plant compounds: Vitamin C, pycnogenol, grape seed extract, and alpha lipoic acid.

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. There are some indications that resveratrol is a mild anticoagulant ("blood thinner"), and it also may help keep blood vessels to remain open and flexible. Caution should be used by those on blood-thinning drugs. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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Super Cortisol Support Fact Sheet
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Date: December 08, 2005 07:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Super Cortisol Support Fact Sheet

Super Cortisol Support Fact Sheet

Neil E. Levin, CCN, DANLA 10/1/05

LIKELY USERS: People under a lot of stress; People who suffer from stress-related eating; People who may have metabolic syndrome (Syndrome X);

KEY INGREDIENTS: Relora®13, Rhodiola14-20, Reishi 21-24, Green Tea Extract25-32, Holy Basil, Ashwaganda, Banaba, Pantothenic Acid, Calcium Ascorbate, Magnesium, Lecithin, Chromium

MAIN PRODUCT FEATURES: NOW® Super Cortisol Support is an herbal and nutritional formula designed to support healthy adrenal function and maintain healthy cortisol levels. The adrenal glands help the body respond and adjust to stress generated from both internal and external forces. Under chronic stress, cortisol can be overproduced, resulting in weight gain and difficulty in managing healthy blood sugar levels. Super Cortisol Support combines adaptogenic herbs with Chromium, Corosolic Acid and Relora® to help the body manage the negative effects of stress such as abdominal obesity, overeating and low energy levels.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy energy levels throughout the day1-6. Reishi, Rhodiola, Ashwaganda, and Holy Basil support healthy immunity1-9. Along with Chromium, and Corosolic Acid, these herbs also help to support healthy serum glucose levels1-12. Relora® has been included in this formula to alleviate symptoms associated with stress such as irritability and nervous tension13.

This formula is recommended by Hyla Cass, MD.

This is the first Cortisol formula to use Relora®, a natural proprietary blend of a patented (U.S. Patent No. US 6,582,735) extract of Magnolia officinalis and a patent-pending extract from Phellodendron amurense. Relora® was developed as an ingredient for dietary supplements and functional foods that could be used in stress management and for stress-related appetite control. This patented blend of plant extracts is the result of screening more than fifty plant fractions from traditional plant medicines used around the world. Relora® has excellent stress management properties without causing sedation. Overweight adults may have excessive abdominal fat due to stress-related overeating. Relora® appears to maintain healthy hormone levels in stressed individuals and act as an aid in controlling weight and stress-related eating.33

SERVING SIZE & HOW TO TAKE IT: One capsule, two to three times a day.

COMPLEMENTARY PRODUCTS: Holy Basil, Green Tea, L-Theanine, Licorice Root, Vitamin C, Eleuthero Root, Pantothenic acid

CAUTIONS: None.

SPECIFIC: Some of these ingredients may support the body’s blood sugar controls, so people taking blood sugar medications should inform their physician before using Super Cortisol Support, and their glucose should be monitored when taking this formula so their medication strength can be modulated appropriately to avoid an overdose of medication. No side effects have been noted for this dosage of Relora®.

GENERAL: Pregnant and lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV (2000) Phytomedicine 7(2):85-89.
2. Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H (2000) Phytomedicine 7(5):365-371.
3. Bhattacharya SK, Battacharya A, Sairam K, Ghosal S (2000) Phytomedicine 7(6):463-469.
4. Sembulingam K, Sembulingam P, Namasivayam A (1997) Indian J Physiol Pharmacol 41(2):139-143.
5. Archana R, Namasivayam A (2000) J Ethnopharmacol 73:81-85.
6. Lin Z-B, Zhang H-N (2004) Acta Pharmacol Sin 25(11):1387-1395.
7. Monograph (2002) Alt Med Rev 7(5):421-423.
8. Agarwal R, Divanay S, Patki P, Patwardhan B (1999) J Ethnopharmacol 67:27-35.
9. Archana R, Namasivayam A (2000) J Ethnopharmacol 73:81-85.
10. Vincent JB (2000) J Nutr 130:715-718. 11. Judy WV, Hari SP, Stogsdill WW, Judy JS, Naguib YMA, Passwater R (2003) J Ethnopharmacol 81)1):115-117.
12. Lin Z-B, Zhang H-N (2004) Acta Pharmacol Sin 25(2):191-195.
13. Maruyama Y, Kuribara H, Morita M, Yuzurihara M, Weintraub ST (1998) J Nat Prod 61:135-138.
14. Brown RP, et al. American Botanical Council. Rhodiola rosea: a phytomedicinal overview. g/herbalgram/articleview.asp?a=2333.
15. Kelly GS. Rhodiola rosea: a possible plant adaptogen. Alt Med Rev 2001;3(6):293-302.
16. De Bock K, et al. Acute rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab 2004;14:298-307.
17. Shevtsov VA, et al. A randomized trial of two different doses of a SHR-5 rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine 2003;2-3(10):95-105.
18. Shugarman AE. Men’s Fitness, 2002. As reported on: LookSmart FindArticles. Energy pills that work: can these five supplements help unleash the muscle building power within you? ttp://findarticles.com/p/articles/mi_m1608/is_3_18/ai_83343009/
19. Earnest CP, et al. Effects of a commercial herbal-based formula on exercise performance in cyclists. Med Sci Sports Exerc 2004;36(3):504-9.
20. Wing SL, et al. Lack of effect of rhodiola or oxygenated water supplementation on hypoxemia and oxidative stress. Wilderness Env Med 2003;14(1):9-16.
21. Shu HY. Oriental Materia Medica: A Concise Guide. Palos Verdes, CA: Oriental Healing Arts Press, 1986, 640–1. 22. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.
23. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.
24. 9. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
25. Kono S, Shinchi K, Ikeda N, et al. Green tea consumption and serum lipid profiles: A cross-sectional study in Northern Kyushu, Japan. Prev Med 1992;21:526–31.
26. Yamaguchi Y, Hayashi M, Yamazoe H, et al. Preventive effects of green tea extract on lipid abnormalities in serum, liver and aorta of mice fed an atherogenic diet. Nip Yak Zas 1991;97:329–37.
27. Sagesaka-Mitane Y, Milwa M, Okada S. Platelet aggregation inhibitors in hot water extract of green tea. Chem Pharm Bull 1990;38:790–3.
28. Stensvold I, Tverdal A, Solvoll K, et al. Tea consumption. Relationship to cholesterol, blood pressure, and coronary and total mortality. Prev Med 1992;21:546–53.
29. Tsubono Y, Tsugane S. Green tea intake in relation to serum lipid levels in middle-aged Japanese men and women. Ann Epidemiol 1997;7:280–4.
30. Serafini M, Ghiselli A, Ferro-Luzzi A. In vivo antioxidant effect of green tea in man. Eur J Clin Nutr 1996;50:28–32.
31. Benzie IF, Szeto YT, Strain JJ, Tomlinson B. Consumption of green tea causes rapid increase in plasma antioxidant power in humans. Nutr Cancer 1999;34:83–7.
32. Sasazuki S, Komdama H, Yoshimasu K, et al. Relation between green tea consumption and severity of coronary atherosclerosis among Japanese men and women. Ann Epidemiol 2000;10:401–8.
33. Sufka KJ, et al. Anxiolytic properties of botanical extracts in the chick social separation-stress procedure.Psychopharmacology. 2001 Jan 1;153(2):219-24. PMID: 11205

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Nattokinase Fact Sheet
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Date: December 08, 2005 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nattokinase Fact Sheet

Nattokinase Fact Sheet

Neil E. Levin, CCN, DANLA 8/8/05

LIKELY USERS: People seeking to support heart health and healthy circulation.1-6

KEY INGREDIENTS: Nattokinase, an enzyme

STRUCTURE/FUNCTION USE: Nattokinase is an enzyme isolated from Natto, a traditional Japanese fermented soy food. Natto has been consumed safely for thousands of years for its numerous health benefits. More recently, both clinical and non-clinical studies have demonstrated that Nattokinase supports heart health and promotes healthy circulation. Each serving of NOWR Nattokinase provides 2,000 FU (Fibrinolytic Units) to help keep already healthy levels of blood clotting factors within a normal range. 1-6

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: An assay of 2,000 FU (Fibrinolytic Units) is equivalent to 160 IU on the Urokinase assay. The FU assay measures Nattokinase activity by using the fibrin plate method and measuring the absorption of released low-molecular weight substances.7 NOW Nattokinase is made from non-GE (non-genetically engineered) bacteria (Bacillus subtilis var. Natto) grown on non-GE soybeans and standardized on a base of non-GE, corn-derived maltodextrin.

SERVING SIZE & HOW TO TAKE IT: Take one vegetarian Vcap once or twice a day between meals (without protein).

COMPLEMENTARY PRODUCTS: Vein SupremeTM, Tru-E Bio ComplexTM, Pycnogenol®, garlic, and cayenne

CAUTIONS: None.

SPECIFIC: People with blood coagulation disorders or who take anticoagulant (“blood thinning”) medications (including aspirin) should consult a physician before use. Do not take if prone to bleeding. Unlike some other brands, NOWR Nattokinase contains no Vitamin K (K1 or K2), which would enhance clotting.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S (1995) Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull 18(10):1387-1391
2. Sumi H, Hamada H, Nakanishi K, Hiratani H (1990) Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol 84(3):139-143.
3. Suzuki Y, Kondo K, Ichise H, Tsukamoto Y, Urano T, Umemura K (2003) Dietary Supplementation With Fermented Soybeans Suppresses Intimal Thickening. Nutrition 19:261-264.
4. Suzuki Y, Kondo K, Matsumoto Y, Zhao B-Q, Otsuguro K, Maeda T, Tsukamoto Y, Urano T, Umemura K (2003) Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci 73:1289-1298.
5. Ito H, Suzuki T (2002) Effect of oral administration of nattokinase extract on blood mobility. Society of Analytical Bio-Sciences 25(4):1-5.
6. An Open Clinical Pilot Study to Evaluate the Safety and Efficacy of Natural Super Kinase as an Add-On Oral Fibrinolytic Agent to Low Molecular Weight Heparin and Anti-Platelets in Acute Ischaemic Stroke. (no authors listed) (2004)
7. Method: J of Agri Food Chem, Vol 48 (2000) P3, 210-213, 216



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OsteoBoron™ Fact Sheet
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Date: December 08, 2005 05:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: OsteoBoron™ Fact Sheet

OsteoBoron™ Fact Sheet

Neil E. Levin, CCN, DANLA 8/8/05

LIKELY USERS: People looking for joint support; People looking for bone density support; People who want to normalize Vitamin D levels

KEY INGREDIENTS: FruiteX-B™

STRUCTURE/FUNCTION CLAIMS: Boron is an important trace mineral for bone and joint health throughout life, as well as for the development and maintenance of healthy bone density. 1,2,4,6,8,9 NOW® OsteoBoron™ is a patented (US Patent # 5,962,049) complex of Boron and Fructose that is safe and more bioavailable than other forms of Boron. 3,7 NOW® OsteoBoron™ is a superior form of Boron that has been the subject of clinical studies demonstrating its efficacy in the support of healthy joints. 7,10 NOW® OsteoBoron™ has also been shown to be safer than other Boron supplements. 3,7

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

FruiteX-B™ is a patented ingredient that contains boron in a form that is chemically identical to the natural plant forms of boron found in food (Calcium Fructoborate). In human and animal studies this patented form of boron, taken at an amount equal or equivalent to 6 mg. per day, improved bone ash (bone minerals) and Vitamin D status in Vitamin D deficient subjects. In human studies, measurements of joint discomfort were dramatically reduced when taking this dosage for about 2 months. The dose used in most of these studies was equivalent to 2 capsules a day of NOW® OsteoBoron™, a form that has been shown to be biologically more beneficial than other forms of boron.11

SERVING SIZE & HOW TO TAKE IT: One vegetarian capsule twice a day, preferably at separate meals. This dose can be doubled for people with more severe deficiencies, though a physician should normally be consulted in such cases.

COMPLEMENTARY PRODUCTS: Vitamin D, Calcium, Magnesium, copper, Silica/silicon, natural sources of phytoestrogens (plant sourced), Ipriflavone, Bone Strength or Bone Calcium formulas

CAUTIONS: None.

SPECIFIC: Please note any supplements currently consumed which may also contain boron, such as multiple mineral or multiple vitamin formulas, and cut your serving size of NOW® OsteoBoron™ to compensate. People who eat a lot of produce, fruit and nuts may also get a substantial amount from their food and may want to reduce their servings of NOW® OsteoBoron™ accordingly. NOW® OsteoBoron™ is safer (has less toxicity) than boron citrate. Boron may buffer body levels of estrogen, so women at risk from high estrogen should consult a physician before using NOW® OsteoBoron™, even though this problem has not been noted for food source borons.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
2. Chang EB, Sitrin MD, Black DD (1996) Gastrointestinal, Hepatobiliary, and Nutritional Physiology. Chapter 9, Absorption of Water-Soluble Vitamins and Minerals. Lippincott-Ravin, Philadelpia
3. Miljkovic D (1999) Boron and carbohydrate complexes and uses thereof. U.S. Patent # 5,962,049.
4. Neilson FH (2000) The Emergence of Boron as Nutritionally Important Throughout the Life Cycle. Nutrition 16(7/8):512-514.
5. Schaafsma A, de Vries PJ, Saris WH (2001) Delay of natural bone loss by higher intakes of specific minerals and vitamins. Crit Rev Food Sci Nutr 41(4):225-249.
6. Devirian TA, Volpe SL (2003) The physiological effects of dietary boron. Crit Rev Food Sci Nutr 43(2):219-213.
7. Miljkovic ND, Miljkovic DA, Ercegan GM (2002) Osteoarthritis and Calcium Fructoborate Supplementation: An Open-Label Study. FutureCeuticals Internal Study.
8. Sheng MH-C, Taper J, Veit H, Qian H, Ritchey SJ, Lau K-H W (2001) Dietary Boron Supplementation Enhanced the Action of Estrogen, But Not that of Parathyroid Hormone, to Improve Trabecular Bone Quality in Ovariectomized Rats. Biol Trace Elem Res 81:29-45.
9. Naghii MR, Samman S (1997) The effect of boron supplementation on its urinary excretion and selected cardiovascular risk factors in healthy male subjects. Biol Trace Elem Res 56(3):273-286.
10. Travers RL, Rennie GC, Newnham RE (1990) Boron and Arthritis: The Results of a Double-Blind Pilot Study. Journal of Nutritional Medicine 1:127-132.
11. Periasamy M, et al. (2001) J Org Chem, 66, 3328-3833

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Co-Enzyme B-Complex Fact Sheet
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Date: December 08, 2005 04:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Co-Enzyme B-Complex Fact Sheet

Co-Enzyme B-Complex Fact Sheet

Neil E. Levin, CCN, DANLA 8/1/05

LIKELY USERS: People with poor digestion or low stomach acid, People needing ENERGY, People desiring metabolism support.

KEY INGREDIENTS: CoEnzyme B-Vitamins plus synergists

MAIN PRODUCT FEATURES: B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as cofactors in biochemical reactions. NOWR Co-Enzyme B-Complex contains B Vitamins already in their active or "Coenzyme" forms. This enables the body to use them more quickly and efficiently because, once absorbed, they are transported directly to their site of action, requiring no conversion. 1

B Complex Vitamins are needed by the body for energy production, synthesis of hormones and blood cells, healthy nervous system function, and numerous other metabolic processes 1, 2. The forms of the B Vitamins found in foods and most supplements, however, are not readily utilized by the body. They require conversion into their active forms before they can perform their functions as coenzymes in biochemical reactions 1, 2.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOWR Co-Enzyme B-Complex tablets are enteric coated to enhance bioavailability by allowing delivery to intestinal absorption sites intact, unharmed by stomach acids.2 Our Quality department had to qualify several new ingredients for this formula.

This formula is enhanced with added Coenzyme C10 (CoQ10), Alpha Lipoic Acid, Betaine (TMG), Vitamin C, and both coenzyme forms of B-12 (Methylcobalamin and Dibencoside) and is suitable for vegetarians and vegans.

SERVING SIZE & HOW TO TAKE IT: Two tablets daily, preferably in divided doses. This enteric-coated tablet is best to take between meals (one or more hours before a meal or hours after a meal), as it has an acid-resistant coating that dissolves beyond the stomach and needs to transit quickly past the stomach.

COMPLEMENTARY PRODUCTS: Vitamin C, TMG (Betaine), Lecithin (Choline, Inositol)

CAUTIONS: None.

SPECIFIC: Please discuss your use of B-Vitamins with your physician, especially if you are using any medications.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
2. Chang EB, Sitrin MD, Black DD (1996) Gastrointestinal, Hepatobiliary, and Nutritional Physiology. Chapter 9, Absorption of Water-Soluble Vitamins and Minerals. Lippincott-Ravin, Philadelpia



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Psyllium Husk Fiber Fact Sheet
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Date: December 08, 2005 04:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Psyllium Husk Fiber Fact Sheet

Psyllium Husk Fiber Fact Sheet

Neil E. Levin, CCN, DANLA 8/1/05

LIKELY USERS: People with cholesterol or cardiovascular concerns.1-2 People wanting to increase fiber in their diet3-9

KEY INGREDIENTS: Psyllium Husk Powder, natural flavor

MAIN PRODUCT FEATURES: Psyllium is a true dietary fiber, even though it is classified by some as a laxative or mucilaginous fiber, and is a convenient way to increase intake of dietary fiber because of its high mucilage content. This bulking agent swells considerably when added to liquid, which can help to increase gastrointestinal transit time. This bulking action and increased transit time can play an important role in maintaining healthy gastrointestinal function.3-9 The FDA allows a health claim for products like psyllium husk that provide significant amounts of soluble fiber: Diets low in saturated fat and cholesterol that include 1.7 grams of soluble fiber per day from psyllium husk may reduce the risk of heart disease. One serving of NOW Psyllium Husk Fiber - Orange Flavored provides 2 grams of this soluble fiber.1-2

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: This product has been tested by an independent laboratory to assay the fiber content. This is a vegetarian/vegan product.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, mix 1 heaping teaspoon into at least 12 oz. of water or juice and consume immediately. Be sure to drink plenty of additional fluids throughout the day. Start with smaller amounts and gradually increase over several weeks.

COMPLEMENTARY PRODUCTS:

For GI tract: Triphala, Detox Support, Probiotics, FOS, and healthy oils (fish, flax, olive, virgin coconut, virgin macadamia)

For cardiovascular health: Hawthorn extract, Tru-E Bio Complex (new September 2005), Heart Support, Heart Renew, Cholesterol Support, Cholestatin, Policosanol. Red Yeast Rice CAUTIONS: None.

SPECIFIC: Do not use if you have a bowel obstruction or an ulcer. If you have chronic constipation, diabetes or are obese a physician should monitor the use of this dietary supplement. Side effects are possible with any dietary supplement. This dietary supplement may cause gastrointestinal pain, flatulence and abdominal pain. Tell your doctor if these side effects become severe or do not go away.

NOTICE: This food should be eaten with at least a full glass of liquid. Eating this product without enough liquid may cause choking. Do not eat this product if your have difficulty in swallowing.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. [Code of Federal Regulations] [Title 21, Volume 2] [Revised as of April 1, 2002]
2. Jenkins DJ, Kendall CW, Vuksan V, Vidgen E, Parker T, Faulkner D, et al. Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial. Am J Clin Nutr. May2002;75(5):834-839.
3. McRorie JW, et al. Psyllium is superior to docusate sodium for treatment of chronic constipation. Aliment Pharmacol Ther. May1998;12(5):491-7.
4. Washington N, et al. Moderation of lactulose-induced diarrhea by psyllium: effects on motility and fermentation. Am J Clin Nutr. Feb1998;67(2):317-21.
5. Leib MS. Treatment of chronic idiopathic large-bowel diarrhea in dogs with a highly digestible diet and soluble fiber: a retrospective review of 37 cases. J Vet Intern Med. Jan2000;14(1):27-32.
6. Schwesinger WH, et al. Soluble dietary fiber protects against cholesterol gallstone formation. Am J Surg. Apr1999;177(4):307-10.
7. Davidson MH, et al. Long-term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia. Am J Clin Nutr. Mar1998;67(3):367-76.
8. Jalihal A, et al. Ispaghula therapy in irritable bowel syndrome: improvement in overall well-being is related to reduction in bowel dissatisfaction. J Gastroenterol Hepatol. Sep1990;5(5):507-13.
9. Obata K, et al. Dietary fiber, psyllium, attenuates salt-accelerated hypertension in stroke-prone spontaneously hypertensive rats. J Hypertens. Dec1998;16(12 Pt 2):1959-64.



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Butterbur Extract Fact Sheet
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Date: December 08, 2005 04:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butterbur Extract Fact Sheet

Butterbur Extract Fact Sheet

Neil E. Levin, CCN, DANLA 8/1/05

LIKELY USERS: People wanting to support healthy blood flow to the brain and healthy neurological function 1-6,10 Those maintaining normal seasonal immune responses 7-10

KEY INGREDIENTS: 75 mg of Guaranteed Potency Butterbur Root (Petasites hybridus) Extract, min. 15 Sesquiterpenes as Petasines; 200 mg of Feverfew Leaf (Tanacetum parthenium) min. 0.4% Parthenolides

MAIN PRODUCT FEATURES: Butterbur (Petasites hybridus) is a native shrub of Europe, North America, and Asia that has been used by herbalists for centuries. Modern scientific studies have demonstrated that Butterbur supports healthy blood flow to the brain and healthy neurological function.1-6, 10 In addition, Butterbur may help to maintain balanced seasonal immune responses.7-10 In a synergistic base of guaranteed potency Feverfew leaf.11-26

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW Butterbur is free of harmful levels of Pyrrolizidine Alkaloids (PAs), the undesirable compounds naturally found in Butterbur, so it is safe to use regularly.

SERVING SIZE & HOW TO TAKE IT: Take one VCap one to three times per day, or as directed by your physician.

COMPLEMENTARY PRODUCTS: Magnesium, Ulcetrol, B-2, B-12, Fish Oil (EPA, DHA), SAM-e, Ginger, Ginkgo Biloba

CAUTIONS: None.

SPECIFIC: Do not discontinue use abruptly; taper off use if discontinuing. Discontinue use at least 14 days before surgery or oral surgery. Use with caution if you have ragweed allergies or blood disorders and let your physician know that you plan to use it before you take it. May be contraindicated for pregnant women.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

1. Diener HC, Rahlfs VW, Danesch U (2004) The First Placebo-Controlled Trial of a Special Butterbur Root Exract for the Preventio of Migraine: Reanalysis of Efficacy Criteria. Eur Neurol 51:89-97.
2. Lipton RB, Gobel H, Einhaupl KM, Wilks K, Mauskop A (2004) Petasites hybridus root (butterbur) is an effective preventative treatment for migraine. Neurology 63:2240-2244.
3. Pothmann R, Danesch U (2005) Migraine Preventiuon in Children and Adolescents: Results of an Open Study With a Special Butterbur Root Extract. Headache 45:196-203.
4. Rapaport AM, Bigal ME (2004) Perventive migraine therapy: what is new. Neurol Sci 25:S177-S185.
5. Wu SN, Chen H, Lin YL (2003) The mechanism of inhibitory actions of S-petasin, a sequiterpene of Petasites formosanus, on L-type calcium current in NG108-15 neuronal cells. Planta Med 69(2):118-124.
6. Wang G-J, Wu X-C, Lin Y-L, Ren J, Shum AY-C, Wu Y-Y, Chen C-F (2002) Ca2+ channel blockin effect of iso-S-petasin in rat aoritic smooth muscle cells. Eur J Pharmacol 445(3):239-45.
7. Lee DKC, Carstairs IJ, Haggart K, Jackson CM, Currie GP, Lipworth BJ (2003) Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis. Clin Exp Allergy 33:882-886.
8. Lee DKC, Haggart K, Robb FM, Lipworth BJ (2004) Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids. Clin Exp Allergy 34:110-114.
9. Lee DKC, Gray RD, Robb FM, Fujihara S, Lipworth BJ (2004) A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis. Clin Exp Allergy 34:646-649.
10. (No Author) (2001) Petasites hybridus (Butterbur). Alt Med Rev 6(2):207-209.
11. Hayes NA, et al. The Activity of Compounds Extracted from Feverfew on Histamine Release from Rat Mast Cells. J Pharm Pharmacol. Jun1987;39(6):466-70.
12. 2 Groenewegen WA, et al. A Comparison of the Effects of an Extract of Feverfew and Parthenolide, a Component of Feverfew, on Human Platelet Activity In-vitro. J Pharm Pharmacol. 1990;42(8):553-57.
13 Capasso F. The Effect of An Aqueous Extract of Tanacetum parthenium L. on Arachidonic Acid Metabolism by Rat Peritoneal Leucocytes. J Pharm Pharmacol. Jan1986;38(1):71-72.
14. 4 Bejar E. Parthenolide Inhibits the Contractile Responses of Rat Stomach Fundus to Fenfluramine and Dextroamphetamine but not Serotonin. J Ethnopharmacol. Jan1996;50(1):1-12.
15. 5 Prusinski A, Durko A, Niczyporuk-Turek A. [Feverfew as a Prophylactic Treatment of Migraine]. Neurol Neurochir Pol. 1999;33(Suppl 5):89-95.
16. 6 Barsby RW, et al. Feverfew Extracts and Parthenolide Irreversibly Inhibit Vascular Responses of the Rabbit Aorta. J Pharm Pharmacol. Sep1992;44(9):737-40.
17. 7 Pittler MH, Vogler BK, Ernst E. Feverfew for Preventing Migraine (Cochrane Review). Cochrane Database Syst Rev. 2000;(3):CD002286.
18. 8 Pattrick M, et al. Feverfew in Rheumatoid Arthritis: A Double-blind, Placebo Controlled Study. Ann Rheum Dis. 1989;48:547-49.
19. 9 Makheja AM, et al. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostaglandin Leukotri Med. 1982;8:653-60. 20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada . Ottawa , Canada
20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada. Ottawa, Canada.
21. 14 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press; 1996:119-21.
22. 15 PDR for Herbal Medicines, 2nd ed. Montvale , NJ: Medical Economics Company; 2000:307.
23. 16 Pribitkin ED. Herbal therapy: what every facial plastic surgeon must know. Arch Facial Plast Surg. Apr2001;3(2): 127-32.
24. 17 Schmidt RJ. Plant dermatitis. Compasitae. Clin Dermatol. Apr1986;4(2):46-61.
25. 18 Heck AM, et al. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. Jul2000;57(13): 1221-7.
26. 19 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London : The Pharmaceutical Press; 1996:119-21.



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Triphala Fact Sheet
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Date: December 08, 2005 04:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Triphala Fact Sheet

Triphala Fact Sheet

Neil E. Levin, CCN, DANLA 6/30/05

LIKELY USES: Antioxidant Colon Cleansing, Detoxifying, Digestive, Liver and bile health

KEY INGREDIENTS: Triphala 500 mg, in a combination of fruit powders and extracts

MAIN PRODUCT FEATURES: Triphala is a combination of three fruits (Harada, Amla, and Behada) that has been used in Ayurvedic herbalism for thousands of years. Triphala's historical use as a digestive cleanser and tonifier has been backed up with numerous modern scientific studies demonstrating the positive effects of its component herbs on the gastrointestinal tract. In addition, Triphala has been shown to be a potent antioxidant, protecting cells against the damaging effects of free radicals. May help to dispel worms. Mild-acting internal cleansing; supports liver and gastrointestinal function

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW offers the first - and only - Triphala supplement to combine the fruit powders (400 mg) with the extracts (100 mg) of the fruits (doses given per tablet, there are three tablets per serving). Authorities like Dr. Andrew Weil consider Triphala to be a superior bowel tonic, rather than a laxative, with its benefits increasing over time. Laxatives typically are habit-forming and do not enhance normal body elimination of wastes; this is not the case with (moderate doses of) Triphala. This formula is suitable for vegetarians and is offered in tablet form.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every three tablets provide 1,200 mg. (1.2 gram) Triphala powder and 300 mg. (0.30 gram) Triphala extract. Both the powder and the extract provide the three fruits in equal ratios, by weight. Take one to three servings per day, between meals.

COMPLEMENTARY PRODUCTS: Fiber sources (psyllium, pectin, etc.), Detox Support, Plant Enzymes, Virgin Coconut Oil, Dr. Verghese Liver Formula, Bentonite Powder, Probiotics (GR-8 Dophilus, 4x6 Acidophilus, etc.), Electrolytes (minerals) CAUTIONS: none

PRODUCT SPECIFIC: Contraindicated during pregnancy and lactation; avoid during menstruation; not appropriate for the very young or very old or the convalescent.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.

Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES: Abraham S, Kumar MS, Sehgal PK, Nitish S, Jayakumar ND. Evaluation of the inhibitory effect of triphala on PMN-type matrix metalloproteinase (MMP-9). J Periodontol. 2005 Apr;76(4):497-502. PMID: 15857087 Al-Rehaily AJ, Al-Howiriny TA, Al-sohaiani MO, Rafatullah S. (2002) Gastroprotective effects of 'Amla" Emblica officinalis on in vivo test models in rats. Phytomedicine 9(6):515-522.

Arora S, Kaur K, Kaur S. Indian medicinal plants as a reservoir of protective phytochemicals. Teratog Carcinog Mutagen. 2003;Suppl 1:295-300. PMID: 12616620 Jagetia GC, Baliga MS, Malagi KJ, Sethukumar Kamath M. The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation. Phytomedicine. 2002 Mar;9(2):99-108. PMID: 11995956 Jagetia GC, Malagi KJ, Baliga MS, Venkatesh P, Veruva RR (2003) Triphala, an Ayurvedic Rasayana Drug, Protects Mice Against Radiation-Induced Lethality by Free-Radical Scavenging. J Alt Complement Med 10(6):971-978. Jagetia GC, Rao Sk,, Baliga MS, Babu K (2004) The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary study. Phytother Res 18(7):561-565.

Kaur S, Michael H, Arora S, Harkonen PL, Kumar S. The in vitro cytotoxic and apoptotic activity of Triphala--an Indian herbal drug. J Ethnopharmacol. 2005 Feb 10;97(1):15-20. Epub 2004 Dec 25. PMID: 15652269 Kaur S, Arora S, Kaur K, Kumar S. The in vitro antimutagenic activity of Triphala--an Indian herbal drug. Food Chem Toxicol. 2002 Apr;40(4):527-34. PMID: 11893411 Sabu MC, Kuttan R (2002) Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol 81:155-160. Sairam K, Rao CV, Dora M, Babu K, Kumar V, Agrawal VK, Goel RK (2002) Antiulcerogenic effect of methanolic extract of Emblica Officinals: an experimental study. J Ethnopharmacol 82:1-9. Sandhya T, Lathika KM, Pandey BN, Mishra KP. Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drug. Cancer Lett. 2005 May 14; [Epub ahead of print] PMID: 15899544 Tamhane MD, Thorat SP, Rege NN, Dahanukar SA (1997) Effect of oral administration of Terminalia chebula on gastric emptying: an Experimental study. J Postgrad Med 43(1):12-13. Vani T, Rajani M, Sarkar S, and Shishoo CJ. Antioxidant Properties of the Ayurvedic Formulation Triphala and its Constituents. International Journal of Pharmacognosy Vol 35, No. 5, 1997:313-3

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Carnitine Creatinate
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Date: December 08, 2005 03:33 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Carnitine Creatinate

Carnitine Creatinate

Neil E. Levin, CCN, DANLA 6/30/05

LIKELY USERS: Athletes, Bodybuilders, Dieters, People who consume a lot of fat, People needing cardiovascular support (energy for the heart), People who need quick energy, especially for fast muscle response, People with muscle wasting problems (including the elderly), Weightlifters

KEY INGREDIENTS: L-Carnitine and Creatine Monohydrate

MAIN PRODUCT FEATURES: Carnitine Creatinate Monohydrate is a specialized form of Creatine bonded to L-Carnitine. Creatine is a compound natural to the human body that aids in the regeneration of ATP, the chemical energy used by muscle tissue. During exercise, large quantities of creatine are irreversibly consumed. Clinical studies have shown that oral supplementation with Creatine can increase the amount of Creatine available in muscles for ATP production. L-Carnitine is an amino acid that is necessary for the transfer of fatty acids into the fat-burning parts of the cell, facilitating energy production from fat. The combination of these two compounds can produce a synergistic effect, making NOW® Carnitine Creatinate an ideal energy supplement.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Carnitine and Creatinate Monohydrate is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product. Protected by U.S. Patent No. 5,994,581 (L-Carnitine Creatinate Monohydrate).

Look at the price: this is a better way to buy both supplements than purchasing them separately.

This formula is suitable for vegetarians and is offered in both tablet and powder forms.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every two tablets provide 1,000 mg. (one gram) each of both L-Carnitine and Creatine Monohydrate. Or one teaspoon provides 1,150 mg.) each of both L-Carnitine and Creatine Monohydrate. Take one or more servings per day with a carbohydrate source, such as fruit juice or sports drinks.

COMPLEMENTARY PRODUCTS: CoQ10, carbohydrates, B-Complex vitamins, chromium, vanadium, Hawthorn leaf and flower extract, protein supplements. Adaptogenic herbs: ginsengs, Eleuthero, Rhodiola, Maca, Ashwaganda, licorice root

CAUTIONS: none.

PRODUCT SPECIFIC: This product is very sensitive to moisture. Please keep in the original packaging or in a moisture resistant container. Do not take more than 20 grams per day. Discontinue use if cramps of stomach upset occur, especially if taking large doses. Do not take if kidney disease is present. Do not use large doses of caffeine with creatine, as it may increase the possibility of muscle cramping.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.

Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Fang S-M (1998) Carnitine Creatinate. U.S. Patent 5,994,581.

L-CARNITINE:

Beers MH, Berkow R (eds). The Merck Manual of Diagnosis and Therapy, 17th ed. Whitehouse Station, NJ: Merck and Co., Inc, 1999, 881-3.

Broquist HP (1994) Carnitine, in Modern Nutrition in Health and Disease, 8th ed., Shils ME, Olson JA, Shike M (eds.) Lea & Febiger, Philadelphia, pp. 459-465. Casey A, Greenhoff PL (2000) Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance? Am J Clin Nutr 72(suppl):607S-17S. Columbani P, Wenk C, Kunz I, et al. Effect of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double blind crossover field study. Eur J Appl Physiol 1996;73:434-9.

Dal Negro R, Pomari G, Zoccatelli O, Turco P. L-carnitine and rehabilitative respiratory physiokinesitherapy: metabolic and ventilatory response in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1986;24:453-6.

Dal Negro R, Turco P, Pomari C, De Conti F. Effects of L-carnitine on physical performance in chronic respiratory insufficiency. Int J Clin Pharmacol Ther Toxicol 1988;26:269-72.

Del Favero A. Carnitine and gangliosides. Lancet 1988;2:337 [letter].

Dipalma JR. Carnitine deficiency. Am Fam Physician 1988;38:243–51.

Digiesi V, Palchetti R, Cantini F. The benefits of L-carnitine in essential arterial hypertension. Minerva Med 1989;80:227-31.

Giamberardino MA, Dragani L, Valente R, et al. Effects of prolonged L-carnitine administration on delayed muscle pain and CK release after eccentric effort. Int J Sports Med 1996;17:320-4.

Green RE, Levine AM, Gunning MJ. The effect of L-carnitine supplementation on lean body mass in male amateur body builders. J Am Diet Assoc 1997;(suppl):A-72.

Harris RC, Soderlund K, Hultman E (1992) Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 83(3):367-374.

Kendler BS. Carnitine: an overview of its role in preventive medicine. Prev Med 1986;15:373–90.

Kobayashi A, Masumura Y, Yamazaki N. L-carnitine treatment for congestive heart failure—experimental and clinical study. Jpn Circ J 1992;56:86–94.

Murray MT. The many benefits of carnitine. Am J Natural Med 1996;3:6-14 [review].

Tamamogullari N, Silig Y, Icagasioglu S, Atalay A. Carnitine deficiency in diabetes mellitus complications. J Diabetes Complications 1999;13:251–3.

Yesilipek MA, Hazar V, Yegin O. L-Carnitine treatment in beta thalassemia major. Acta Haematol 1998;100:162-3. CREATINE MONOHYDRATE: Almada A, Mitchell T, Earnest C. Impact of chronic creatine supplementation on serum enzyme concentrations. FASEB J 1996;10:4567.

Becque MD, Lochmann JD, Melrose DR. Effects of oral creatine supplementation on muscular strength and body composition. Med Sci Sports Exerc 2000;32:654-8.

Casey A, Constantin-Teodosiu D, Howell S, et al. Creatine supplementation favorably affects performance and muscle metabolism during maximal intensity exercise in humans. Am J Physiol 1996;271:E31-E7.

Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci 1996;91:113-8.

Earnest C, Almada A, Mitchell T. Influence of chronic creatine supplementation on hepatorenal function. FASEB J 1996;10:4588.

Earnest CP, Snell PG, Rodriguez R, et al. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 1995;153:207-9.

Felber S, Skladal D, Wyss M, et al. Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study. Neurol Res 2000;22:145-50.

Feldman EB. Creatine: a dietary supplement and ergogenic aid. Nutr Rev 1999;57:45–50.

Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in man. Am J Physiol 1996;271:E821–6.

Green AL, Simpson EJ, Littlewood JJ, et al. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiol Scand 1996;158:195-202.

Greenhaff PL. Creatine and its application as an ergogenic aid. Int J Sport Nutr 1995;5:94-101.

Greenhaff PL. The nutritional biochemistry of creatine. J Nutr Biochem 1997;8:610-8 [review].

Greenhaff PL, Bodin K, Soderlund K, et al. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Am J Physiol 1994;266:E725-30.

Greenhaff PL, Casey A, Short AH, et al. Influence of oral creatine supplementation on muscle torque during repeated bouts of maximal voluntary exercise in man. Clin Sci 1993;84:565-71.

Harris RC, Soderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci 1992;83:367-74.

Hultman E, Soderlund K, Timmons J, et al. Muscle creatine loading in man. J Appl Physiol 1996;81:232–7.

Juhn MS, O’Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593–5.

Kreider RB, Ferreira M, Wilson M, et al. Effects of creatine supplementation on body composition, strength, and sprint performance. Med Sci Sports Exerc 1998;30:73-82.

Poortmans JR, Auquier H. Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men. Eur J Appl Physiol Occup Physiol 1997;76:566–7.

Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108–10.

Pritchard NR, Kaira PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252–3 [letter].

Sewell DA, Robinson TM, Casey A, et al. The effect of acute dietary creatine supplementation upon indices of renal, hepatic and haematological function in human subjects. Proc Nutr Soc 1998;57:17A.

Silber ML. Scientific facts behind creatine monohydrate as a sports nutrition supplement. J Sports Med Phys Fitness 1999;39:179–88 [review].

Sipila I, Rapola J, Simell O, et al. Supplementary creatine as a treatment for gyrate atrophy of the choroid and retina. N Engl J Med 1981;304:867-70.

Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5-weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

Stout JR, Eckerson J, Noonan D, et al. The effects of a supplement designed to augment creatine uptake on exercise performance and fat-free mass in football players. Med Sci Sports Exerc 1997;29:S251.

Tarnopolsky MA. Potential benefits of creatine monohydrate supplementation in the elderly. Curr Opin Clin Nutr Metab Care 2000;3:497-502 [review].

Tarnopolsky M, Martin J. Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology 1999;52:854-7.

Tarnopolsky MA, Roy BD, MacDonald JR. A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies. Muscle Nerve 1997;20:1502-9.

Toler SM. Creatine is an ergogen for anaerobic exercise. Nutr Rev 1997;55:21-5 [review].

Vandenberghe K, Gills N, Van Leemputte M, et al. Caffeine counteracts the ergogenic action of muscle creatine loading. J Appl Physiol 1996;80:452–7.

Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training. J Appl Physiol 1997;83:2055-63.

Walter MC, Lochmuller H, Reilich P, Klopstock T, Huber R, Hartard M, Hennig M, Pongratz D, Muller-Felber W. Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study. Neurology. 2000 May 9;54(9):1848-50. PMID: 10802796

Walter MC, Reilich P, Lochmuller H, Kohnen R, Schlotter B, Hautmann H, Dunkl E, Pongratz D, Muller-Felber W. Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. J Neurol. 2002 Dec;249(12):1717-22. PMID: 12529796



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Vitanet ®

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AHCC® Fact Sheet - from Now Foods.
TopPreviousNext

Date: December 08, 2005 10:20 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: AHCC® Fact Sheet - from Now Foods.

AHCC® Fact Sheet

Neil E. Levin, CCN, DANLA 6/30/05

LIKELY USERS: People needing increased activity of their Natural Killer cells; People seeking improved immune system response; People with a need for tissue repair; People with oxidative challenges; People seeking to increase liver function People defying aging or with a need to improve cellular integrity.

KEY INGREDIENTS: AHCC® (Active Hexose Correlated Compound)

MAIN PRODUCT FEATURES: AHCC® is a proprietary extract produced from specially cultivated and hybridized mushrooms. According to extensive research in humans, as well as numerous non-clinical studies, AHCC®supports immune system function through its effects on macrophages and NK (Natural Killer) Cells. NK cells and the intercellular mediators they produce are critical for the maintenance of healthy cell cycle function. AHCCR® has also been shown possess antioxidant properties, and supports healthy liver function.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: AHCC® (Active Hexose Correlated Compound) is a patented ingredient that has been the subject of research studies. It is supported by the scientific staff in the laboratories of both NOW Foods and the raw material supplier, both of which have a mutual interest in protecting the integrity and efficacy of this product.

AHCC® is a rich source of polysaccharides such as beta glucan 1,3 and activated hemicellulose produced by enzymatic modification of organic medicinal mushrooms, including shiitake. It also has been shown to support normal levels of macrophages and cytokines, further strengthening the immune system.

This formula is suitable for vegetarians and is offered in Vcaps.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, take 2 Vcaps® 3 times daily, preferably on an empty stomach.

COMPLEMENTARY PRODUCTS: Antioxidants, Astragalus, Colostrum, Dr. Verghese Liver Formula, Immune Renew, Indole-3-Carbinol (I3C), Inositol Hexaphosphate (IP-6),

CAUTIONS: None.

PRODUCT SPECIFIC: None

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems. Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

DISCLAIMER: Information given here may vary from what is shown on the product label because this represents my own professional knowledge and understanding of the science underlying the formula and ingredients. The information in this review should not be used as diagnosis, prescription or as a specific product claim.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G. (2003) Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infectin in mice in the hindlimb-unloading model of spaceflight conditions. J Appl Physiol 95:491-496.

Burikhanov RB, Wakame K, Igarashi Y, Wang S, Matsuzaki S (2000) Suppressive Effect of Active Hexose Correlated Compound (AHCC®) on Thymic Apoptosis Induced by Dexamethasone in the Rat. Endocrine Regulations 34:181-188. Matsui Y, et al. (2002) Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study. J Hepatol. 2002 Jul;37(1):78-86. PMID: 12076865 Matsushita K, et al. (1998) Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anti-Cancer Drugs 9:343-350. Sun B, Wakame K, Mukoda T, Toyoshima A. Kanazawa T, Kosuna K (1997) Preventive Effects of AHCC® on Carbon Tetrachloride Induced Liver Injury in Mice. Nat Med 51(4):310-315.

Ye SF, Ichimura K, Wakame K, Ohe M. Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress. Life Sci. 2003 Dec 19;74(5):593-602. PMID: 14623030 Ye SF, Wakame K, Ichura K, Matsuzaki S (2004) Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat. Endocr Regul 38(1):7-13.



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AHCC and Vitanet Great Combination

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VitaBerry Plus+ Fact Sheet
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Date: December 07, 2005 05:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: VitaBerry Plus+ Fact Sheet

VitaBerry Plus+ Fact Sheet

Neil E. Levin, CCN, DANLA 3/18/05

LIKELY USERS: Antioxidant users who want the best food source formula; People seeking polyphenols or ellagic acid supplements; Those who don’t eat fruit and want some of their benefits

KEY INGREDIENTS: VitaBerry extract, Hi-Active Orange Extract, Pomegranate Extract (420 mg) (400 mg) (100 mg)

MAIN PRODUCT FEATURES: This is a high antioxidant (high ORAC: 2,500 units per serving of oxygen radical absorbing capacity), proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry extract, Grape & Grape seed extract, Raspberry & Raspberry seed extract, Cranberry, Prune, Tart Cherry, Wild Bilberry extract & Strawberry powder. Fortified with Hi-Active Orange Extract (Freeze-dried Orange (Citrus sinensis) powder with minimum of 40% vitamin C) and Pomegranate Extract (80% Polyphenols and 40% Ellagic Acid).

Provides a broad-spectrum antioxidant blend with phytochemicals such as anthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol etc. in a single “0” size vegetarian capsule. There is a synergistic effect of mixing fruit antioxidants that provides antioxidant protection greater than is predicted by measuring each fruit source used in the mix individually.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: There will be some natural variation in color, taste and odor from these fruit sources. A special freeze drying technique preserves the antioxidant value of whole fruits in a concentrated form.

SERVING SIZE & HOW TO TAKE IT: Serving is 2 Vcaps. Take one or more servings per day as an antioxidant supplement. May be taken with food or on an empty stomach (this is food).

COMPLEMENTARY PRODUCTS: All antioxidants.

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This information has not been reviewed by the FDA or the company posting it. Information given here may vary from what is given on the product label because this page represents my understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc). 2004 Jan;69(1):75-80, 1 p preceding 75. Review. PMID: 14972022

Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 2002 Jul 15;22(14):6114-20. PMID: 12122072

Huang D, Ou B, Prior RL. The Chemistry behind Antioxidant Capacity Assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-1856. PMID: 15769103

Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. PMID: 12323088

Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002 Dec 18;50(26):7731-7. PMID: 12475297

Prior RL, Cao G. Analysis of botanicals and dietary supplements for antioxidant capacity: a review. J AOAC Int. 2000 Jul-Aug;83(4):950-6. Review. PMID: 10995120

Prior RL, Cao G. In vivo total antioxidant capacity: comparison of different analytical methods. Free Radic Biol Med. 1999 Dec;27(11-12):1173-81. Review. PMID: 10641708

Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch-Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples. J Agric Food Chem. 2003 May 21;51(11):3273-9. PMID: 12744654

Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33. PMID: 11999391

Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31. PMID: 12448828

Sofic E, Rustembegovic A, Kroyer G, Cao G. Serum antioxidant capacity in neurological, psychiatric, renal diseases and cardiomyopathy. J Neural Transm. 2002 May;109(5-6):711-9. PMID: 12111462

Stintzing FC, Stintzing AS, Carle R, Frei B, Wrolstad RE. Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem. 2002 Oct 9;50(21):6172-81. PMID: 12358498

Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37. PMID: 15186133

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Enzogenol® Pine Bark Extract Fact Sheet
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Date: December 07, 2005 05:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Enzogenol® Pine Bark Extract Fact Sheet

Enzogenol® Pine Bark Extract Fact Sheet

Neil E. Levin, CCN, DANLA 4/14/05

LIKELY USERS: Those seeking antioxidant protection; People trying to defeat the effects of aging KEY INGREDIENTS: Enzogenol® from New Zealand Pine Tree bark (Pinus radiata) Rutin (200 mg) and Grape Seed Extract (50 mg)

MAIN PRODUCT FEATURES: Enzogenol® is a powerful formulation of antioxidant bioflavonoids extracted from the bark of the New Zealand Pine (Pinus radiata) that is comparable to flavonoid formulations of other pine bark products. The flavonoids found in Enzogenol have been shown in clinical and non-clinical studies to support cardiovascular health and to protect cells and tissues from the damaging effects of oxidative stress. NOW® Enzogenol® also contains Rutin and Grape Seed Extract for their synergistic antioxidant benefits.

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: Enzogenol® is a powerful and highly effective formulation of antioxidants extracted from fresh New Zealand pine bark – one of the most comprehensive complexes of natural antioxidants. A breakthrough in processing technology combines all of these antioxidants in an Enzogenol® capsule in exactly the same ratios as are present in the tree's bark. What's more, the revolutionary pure-water extraction process doesn't use toxic solvents like traditional extraction processes do.

SERVING SIZE & HOW TO TAKE IT: One to four capsules a day as an antioxidant dietary supplement.

COMPLEMENTARY PRODUCTS: Other antioxidants including Vitamin C, VitaBerry Plus+TM, Alpha Lipoic Acid, NAC, etc.

CAUTIONS: There are no specific cautions with this product.

GENERAL CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is given on the product label because it represents my own understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993 Oct 23;342(8878):1007-11. PMID: 8105262 Keli SO, Hertog MG, Feskens EJ, Kromhout D. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study. Arch Intern Med. 1996 Mar 25;156(6):637-42. PMID: 8629875

Ames, BN, Shigenaga, MK, Hagen, TM (1993). Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA 90, 7915-7922



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TMG Fact Sheet
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Date: December 07, 2005 02:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: TMG Fact Sheet

TMG Fact Sheet

Neil E. Levin, CCN, DANLA 03/07/05

LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.

MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.

TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.

Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.

ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.

TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.

DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.

SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.

COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.

People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.

This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

General:

Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791

Methylation:

Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review].

Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30.

Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review].

Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.

Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.

Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.

Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

Homocysteine:

Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.

Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361

Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203

Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.

Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.

Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.

Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499

Liver function:

Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].

Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.

Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.

Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329

Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277

Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.

Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887

Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612

Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.

McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907

Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.

Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439

Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].

Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644

Autism & Seizures:

Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.

Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.

Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.

Immunity:

Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.

Safety:

Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082



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Allibiotic CF Fact Sheet
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Date: December 07, 2005 01:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Allibiotic CF Fact Sheet

Allibiotic CF Fact Sheet

Neil E. Levin, CCN, DANLA 03/09/05

LIKELY USERS: People seeking support of the immune system and intestinal flora

KEY INGREDIENTS: Allicin (“AlliSure” patented, stabilized allicin from fresh garlic); Olive Leaf Extract (Olea Europaea with 18% minimum Oleuropein content); Elderberry extract, from fruit/berry, 60:1 concentrate (equivalent to 2,500 mg. of fresh berries of Sambucus nigra); Oil of Oregano (wild oregano from Origanum vulgare) ImmunEnhancer AG (trademarked Arabinogalactan from Larch Tree, Larix occidentalis)

MAIN PRODUCT FEATURES: AlliSure is the clinically tested, patented and stable form of allicin. Not allicin potential, but actual allicin. Allicin represents the immune supporting nutrients of raw garlic, and is chemically similar to penicillin, though with different physical properties. AlliSure shares garlic’s abilities to help maintain healthy cholesterol and blood pressure levels, and also has been shown to raise levels of a key T cell to enhance immune system function. Like raw garlic, AlliSure has antimicrobial properties linked to its ability to react with sulfur-containing metabolic enzymes. Allicin is also shown in studies to play a role in controlling blood sugar and abnormal cell growth.

Black Elderberries have strong antioxidant properties, containing flavonoids like anthocyanidins. They have been studied in relation to inhibition of viral replication and of minor inflammations.

Olive Leaf has been used as an antioxidant, cholesterol and blood viscosity regulator, and vasodilator. But its most important use has been as a way to help the body deal with undesirable organisms in the vital respiratory and intestinal areas.

Oil of Oregano (wild oregano, wild marjoram) contains carvacrol and thymol, which are responsible for much of its antimicrobial activities. It also has some anti-inflammatory effects.

Arabinogalactan from Larch tree bark (ImmunEnhancer AG) can help speed the immune system’s response to undesirable organisms and is often compared to Echinacea. It has also been shown to promote the growth of beneficial intestinal bacteria.

ADDITIONAL PRODUCT INFORMATION: Patented and trademarked ingredients enhance quality controls and have clinical research. Rosemary Oil provides antioxidant protection for the capsule contents. Enteric coating protects the capsule from stomach acid to deliver its contents past the stomach. This helps to assure full potency and reduces the possibility of the oils repeating.

SERVING SIZE & HOW TO TAKE IT: One softgel twice daily, preferably with meals. Try one before using the full dose.

COMPLEMENTARY PRODUCTS: Probiotics, Antioxidants, D-Flame

CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Discontinue use if any uncomfortable side effects occur. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

ALLICIN:

Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Adv Ther. 2001 Jul-Aug;18(4):189-93. (AlliSure was used in this study.)

Abramovitz D, Gavri S, Harats D, Levkovitz H, Mirelman D, Miron T, Eilat-Adar S, Rabinkov A, Wilchek M, Eldar M, Vered Z. Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet. Coron Artery Dis. 1999 Oct;10(7):515-9. PMID: 10562920

Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997 Oct;41(10):2286-8. PMID: 9333064

Cellini L, Di Campli E, Masulli M, Di Bartolomeo S, Allocati N. Inhibition of Helicobacter pylori by garlic extract (Allium sativum). FEMS Immunol Med Microbiol. 1996 Apr;13(4):273-7. PMID: 8739190

Chowdhury AK, Ahsan M, Islam SN, Ahmed ZU. Efficacy of aqueous extract of garlic & allicin in experimental shigellosis in rabbits. Indian J Med Res. 1991 Jan;93:33-6.

Eilat S, Oestraicher Y, Rabinkov A, Ohad D, Mirelman D, Battler A, Eldar M, Vered Z. Alteration of lipid profile in hyperlipidemic rabbits by allicin, an active constituent of garlic. Coron Artery Dis. 1995 Dec;6(12):985-90. PMID: 8723021

Elkayam A, Mirelman D, Peleg E, Wilchek M, Miron T, Rabinkov A, Oron-Herman M, Rosenthal T. The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Am J Hypertens. 2003 Dec;16(12):1053-6. PMID: 14643581

Feldberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Sundstrom DC, Thompson NH. In vitro mechanism of inhibition of bacterial cell growth by allicin. Antimicrob Agents Chemother. 1988 Dec;32(12):1763-8.

Focke M, Feld A, Lichtenthaler K. Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase. FEBS Lett. 1990 Feb 12;261(1):106-8.

Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. Nutr Cancer. 2000;38(2):245-54. PMID: 11525603

Patya M, Zahalka MA, Vanichkin A, Rabinkov A, Miron T, Mirelman D, Wilchek M, Lander HM, Novogrodsky A. Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Int Immunol. 2004 Feb;16(2):275-81. PMID: 14734613

Rabinkov A, Miron T, Mirelman D, Wilchek M, Glozman S, Yavin E, Weiner L. S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):144-153. PMID: 11118647

Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998 Feb 2;1379(2):233-44. PMID: 9528659

Sela U, Ganor S, Hecht I, Brill A, Miron T, Rabinkov A, Wilchek M, Mirelman D, Lider O, Hershkoviz R. Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Immunology. 2004 Apr;111(4):391-9. PMID: 15056375

Shadkchan Y, Shemesh E, Mirelman D, Miron T, Rabinkov A, Wilchek M, Osherov N. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J Antimicrob Chemother. 2004 May;53(5):832-6. Epub 2004 Mar 24. PMID: 15044429

Tsai Y, Cole LL, Davis LE, Lockwood SJ, Simmons V, Wild GC. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Planta Med. 1985 Oct;(5):460-1. PMID: 3001801

Uchida Y, Takahashi T, Sato N. [The characteristics of the antibacterial activity of garlic (author's transl)] Jpn J Antibiot. 1975 Aug;28(4):638-42. PMID: 1099271

Yasuo Yamada and Keizô Azuma. Evaluation of the In Vitro Antifungal Activity of Allicin. Antimicrob Agents Chemother. 1977 April; 11(4): 743–749.

ELDERBERRY:

Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 423.

Gruenwald J, Brendler T, Jaenicke C, et al. (eds). PDR for Herbal Medicines. Montvale, NJ: Medical Economics, 1998, 1116–7.

Mascolo N, Autore G, Capasso G, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987;1:28–31.

Murkovic M, Abuja PM, Bergmann AR, et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. Feb2004;58(2):244-9.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press, 1996, 104–5.

Yesilada E. Inhibitory Effects of Turkish Folk Remedies on Inflammatory Cytokines: Interleukin-1Alpha, Interleukin-1Beta and Tumor Necrosis Factor Alpha. J Ethnopharmacol. Sept1997;58(1):59-73. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radical Biol Med 2000;29:51–60.

Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995;1:361–9.

OLIVE LEAF EXTRACT:

American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.

Bennani-Kabchi N, et al. Effects of Olea europea var. oleaster leaves in hypercholesterolemic insulin-resistant sand rats. Therapie. Nov1999;54(6):717-23.

Bisignano G, et al. On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. J Pharm Pharmacol. Aug1999;51(8):971-4. Gonzalez M, et al. Hypoglycemic activity of olive leaf. Planta Medica. 1992;58:513-515. Visoli F, et al. Oleuropein protects low density lipoprotein from oxidation. Life Sciences. 1994;55:1965-71. PDR for Herbal Medicines, 2nd edition. Montvale, NJ: Medical Economics Company; 2000:557.

Petroni A, et al. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.Thromb Res. Apr1995;78(2):151-60. Pieroni A, et al. In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves. Pharmazie. Oct1996;51(10):765-8. Zarzuelo A, et al. Vasodilator effect of olive leaf. Planta Med. Oct1991;57(5):417-9. OREGANO OIL (OIL OF OREGANO, WILD OREGANO, WILD MARJORAM):

Dorman HJ, et al. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. Feb2000;88(2):308-16. Force M, et al. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. May2000;14(3):213-4.

Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999;86:985–90.

Kelm MA, Nair MG, Strasburg GM. Antioxidant and Cyclooxygenase Inhibitory Phenolic Compounds from Ocimum sanctum Linn. Phytomedicine. Mar2000;7(1):7-13. Lamaison JL, et al. Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv. 1991;66(7):185-8.

Ponce MM, Navarro AI, Martinez GMN, et al. In vitro effect against Giardia of 14 plant extracts. Rev Invest Clin 1994;46:343–7 [in Spanish].

Stiles JC, Sparks W, Ronzio RA. The inhibition of Candida albicans by oregano. J Applied Nutr 1995;47:96–102.

Tantaoui EA, Beraoud L. Inhibition of growth and aflatoxin production in Aspergillus parasiticus by essential oils of selected plant materials. J Environ Pathol Toxicol Oncol 1994;13:67–72. ImmunEnhancer AG (Larch tree Arabinogalactan)

Corado J, et al. Impairment of Natural Killer (NK) Cytotoxic Activity in Hepatitis C Virus (HCV) Infection. Exp Immunol. 1997;109:451-457. Currier NL, Lejtenyi D, Miller SC. Effect over time of in-vivo administration of the polysaccharide arabinogalactan on immune and hemopoietic cell lineages in murine spleen and bone marrow. Phytomedicine. 2003 Mar;10(2-3):145-53. PMID: 12725568

Egert D, et al. Studies on Antigen Specificity of Immunoreactive Arabinogalactan Proteins Extracted from Baptisia tinctoria and Echinacea purpurea. Planta Med. 1992;58:163-165. Gonda R, et al. Arabinogalactan Core Structure and Immunological Activities of Ukonan C, An Acidic Polysaccharide from the Rhizome of Curcuma longa. Biol Pharm Bull. 1993;16:235-238. Hagmar B, et al. Arabinogalactan Blockade of Experimental Metastases to Liver by Murine Hepatoma. Invasion Metastasis. 1991;11:348-355. Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev. 1999 Apr;4(2):96-103. Review. PMID: 10231609

Kim LS, Waters RF, Burkholder PM. Immunological activity of larch arabinogalactan and Echinacea: a preliminary, randomized, double-blind, placebo-controlled trial. Altern Med Rev. 2002 Apr;7(2):138-49. PMID: 11991793

Levine PH, et al. Dysfunction of Natural Killer Activity in a Family With Chronic Fatigue Syndrome. Clin Immunol Immunopathol. 1998;88:96-104. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr. 2001 Aug;20(4):279-85. PMID: 11506055

Rolfe RD. The Role of Probiotic Cultures in the Control of Gastrointestinal Health. J Nutr. Feb2000;130(2S Suppl):396S-402S.

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Uchida A. Therapy of Chronic Fatigue Syndrome. Nippon Rinsho. 1992;50:2679-2683.



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Astragalus Fact Sheet
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Date: December 07, 2005 01:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Astragalus Fact Sheet

Astragalus Fact Sheet

Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: Everyone seeking a healthy immune system; Those lacking energy

KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg)

MAIN PRODUCT FEATURES: A Chinese “tonic herb” used in Traditional Chinese Medicine for night sweats, diarrhea and lack of energy. Tonic herbs are often known as “adaptogens”, helping the body adapt to stresses and modulating immune system responses. Some reports credit Astragalus with shortening colds and strengthening the heart.Astragalus additionally contains triterpene glycosides, also known as astragalosides.

ADDITIONAL PRODUCT INFORMATION: Vegetarian formula.May be useful to maintain the patient’s immunity in dialysis patients, those with liver problems and those who have suffered from strokes, according to Chinese studies (not as a treatment for those conditions!).

SERVING SIZE & HOW TO TAKE IT: For everyday use take one to five caps per day, either with meals or on an empty stomach.

COMPLEMENTARY PRODUCTS: Immune Renew, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and other antioxidants.

CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease, though there is some (not enough) evidence that Astragalus may balance immune function for at least one autoimmune disorder. This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES: 1. Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem. 2000 Jul;7(7):715-29.
2. Zhang YD, Shen JP, Zhu SH, Huang DK, Ding Y, Zhang XL. Effects of astragalus (ASI, SK) on experimental liver injury Yao Xue Xue Bao. 1992;27(6):401-6. Chinese. PMID: 1442065
3. Sheng BW, Chen XF, Zhao J, He DL, Nan XY. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Chin Med J (Engl). 2005 Jan;118(1):43-9. PMID: 15642225
4. Yesilada E, Bedir E, Calis I, Takaishi Y, Ohmoto Y. Effects of triterpene saponins from Astragalus species on in vitro cytokine release. J Ethnopharmacol. 2005 Jan 4;96(1-2):71-7. PMID: 15588652
5. Li C, Cao L, Zeng Q. Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors' expression. J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):379-84. PMID: 15587404
6. Wang SH, Wang WJ, Wang XF, Chen W. [Effect of Astragalus polysaccharides and berberine on carbohydrate metabolism and cell differentiation in 3T3-L1 adipocytes]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Oct;24(10):926-8. Chinese. PMID: 15553830
7. Shao BM, Dai H, Xu W, Lin ZB, Gao XM. Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun. 2004 Oct 8;323(1):133-41. PMID: 15351712
8. Mao SP, Cheng KL, Zhou YF. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Feb;24(2):121-3. Chinese. PMID: 15015443
9. Guo FC, Williams BA, Kwakkel RP, Li HS, Li XP, Luo JY, Li WK, Verstegen MW. Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poult Sci. 2004 Feb;83(2):175-82.
10. Shao BM, Xu W, Dai H, Tu P, Li Z, Gao XM. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1103-11. PMID: 15249203
11. Zhang BQ, Hu SJ, Shan QX, Sun J, Xia Q. [Relaxant effect of Astragalus membranaceus on smooth muscle cells of rat thoracic aorta.] Zhejiang Da Xue Xue Bao Yi Xue Ban. 2005 Jan;34(1):65-8. Chinese. PMID: 15693127
12. Luo Y, Qin Z, Hong Z, Zhang X, Ding D, Fu JH, Zhang WD, Chen J. Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia. Neurosci Lett. 2004 Jun 17;363(3):218-23. PMID: 15182947
13. Tan BK, Vanitha J. Immunomodulatory and antimicrobial effects of some traditional chinese medicinal herbs: a review. Curr Med Chem. 2004 Jun;11(11):1423-30.
14. Shu HY. Oriental Materia Medica: A Concise Guide. Palos Verdes, CA: Oriental Healing Arts Press, 1986, 521–3. 15. Klepser T, Nisly N. Astragalus as an adjunctive therapy in immunocompromised patients. Alt Med Alert 1999;Nov:125–8 [review].
16. Qun L, Luo Q, Zhang ZY, et al. Effects of astragalus on IL-2/IL-2R system in patients with maintained hemodialysis. Clin Nephrol 1999;52:333–4 [letter].
17. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992, 1056.
18. Li SQ, Yuan RX, Gao H. Clinical observation on the treatment of ischemic heart disease with Astragalus membranaceus. Chung Kuo Chung His I Chieh Ho Tsa Chih 1995;15:77–80 [in Chinese].
19. Chen LX, Liao JX, Guo WQ. Effects of Astragalus membranaceus on Left Ventricular Function and Oxygen Free Radical in Acute Myocardial Infarction Patients and Mechanism of Its Cardiotonic Action. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. Mar1995;15(3):141-3.
20. Lei ZY, Qin H, Liao JZ. Action of Astragalus membranaceus on Left Ventricular Function of Angina Pectoris. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. Apr1994;14(4):199-202,195.
21. Geng CS, et al. Advances in Immuno-pharmacological Studies on Astragalus membranaceus. Chin J Integ Trad West Med. 1986;6:62.
22. Shi HM, et al. Intervention of Lidocaine and Astragalus membranaceus on Ventricular Late Potentials. Zhongguo Zhong Xi Yi Jie He Za Zhi. Oct1994;14(10):598-600.
23. Griga IV. Effect of a Summary Preparation of Astragalus cicer on the Blood Pressure of Rats with Renal Hypertension and on the Oxygen Consumption by the Tissues. Farm Zh. 1977;6:64-66.
24. Kurashige S, Akuzawa Y, Endo F. Effects of astragali radix extract on carcinogenesis, cytokine production, and cytotoxicity in mice treated with a carcinogen, N-butyl-N'-butanolnitrosoamine. Cancer Invest. 1999;17(1):30-5.
25. Wei H, Sun R, Xiao W, et al. Traditional Chinese medicine Astragalus reverses predominance of Th2 cytokines and their up-stream transcript factors in lung cancer patients. Oncol Rep. Sep2003;10(5):1507-12.
26. PDR for Herbal Medicines, 2nd edition. Montvale, NJ: Medical Economics Company; 2000:56. American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.



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Immune Renew Fact Sheet
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Date: December 07, 2005 01:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Immune Renew Fact Sheet

Immune Renew Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: Everyone seeking a healthy immune system; People on low carb diets or non-whole grain diets that are lacking dietary beta-glucans

KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg). Proprietary blend of 8 organically grown “medicinal mushrooms” (200 mg)

MAIN PRODUCT FEATURES: Vegetarian formula. Polysaccharides in these US-grown mushrooms grown on organic brown rice include 1,3 Beta-glucans and terpenoids. Beta-glucans may stimulate the immune system in different ways. Triterpenoids may act as mild anticoagulants. Each mushroom may have a different effect; for example, one may stimulate T-cells and another Natural Killer cells, aiding in immune defense. Mushrooms have reported beneficial effects on liver health and promoting normal cell growth.

ADDITIONAL PRODUCT INFORMATION: Some extracts from these kinds of mushrooms have been used medicinally in Japan and China. The mushrooms include Turkey Tail, Sun Mushrooms, Maitake, Cordyceps, Phellinus, Lion’s Mane, Reishi and Shiitake. The astragalus extract also contains naturally occurring astragalosides. Mushrooms may help maintain normal cholesterol and triglyceride levels

SERVING SIZE & HOW TO TAKE IT: For everyday use take one or two caps per day, either with meals or on an empty stomach.

COMPLEMENTARY PRODUCTS: Vitamin C to break down beta-glucan structures for better absorption, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and antioxidants

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease. Use with caution if using anticoagulants or blood pressure medication, as these mushrooms may have mildly synergistic effects to those drugs. Do not use if you have mold or mushroom allergies (or any sensitivities to mushrooms, cheese, etc.), which can potentially result in hives, rashes, breathing difficulties (including dry mouth or throat), stomach distress, diarrhea, or any other unusual side effect.

This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995
2. Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 1999;19(1):65-96.
3. Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002 Nov;60(3):258-74. Epub 2002 Sep 10.
4. Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.
5. Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.
6. Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].
7. Kubo K, Nanba H. Anti-hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20:781–5.
8. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure lowering activity present in the fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988;36:1000–6.
9. Jones K. Shiitake: A major medicinal mushroom. Alt Compl Ther 1998;4:53–9 [review].
10. Taguchi I. Clinical efficacy of lentinan on patients with stomach cancer: End point results of a four-year follow-up survey. Cancer Detect Prevent Suppl 1987;1:333–49.
11. Matsuoka H, Seo Y, Wakasugi H, et al. Lentinan potentiates immunity and prolongs survival time of some patients. Anticancer Res 1997;17:2751–6.
12. Guangwen Y, Jianbin Y, Dongqin L, et al. Immunomodulatory and therapeutic effects of lentinan in treating condyloma acuminata. CJIM 1999;5:190–2.
13. Jones K. Reishi mushroom: Ancient medicine in modern times. Alt Compl Ther 1998;4:256–66 [review].
14. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.
15. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.
16. Suzuki H, et al. Immunopotentiating Substances in Lentinus edodes Mycelial Extract(LEM)-- Activation of Macrophage and Proliferation of Bone Marrow Cell. Nippon Shokakibyo Gakkai Zasshi. Jul1988;85(7): 1430.
17. Suzuki H, et al. Inhibition of the Infectivity and Cytopathic Effect of Human Immunodeficiency Virus by Water-soluble Lignin in an Extract of the Culture Medium of Lentinus edodes Mycelia (LEM). Biochem Biophys Res Commun. Apr1989;160(1):367-73.
18. Gordon M, et al. A Placebo-controlled Trial of the Immune Modulator, Lentinan, In HIV-positive Patients: A Phase I/II Trial. J Med. 1998;29(5-6):305-30.
19. Li JF, et al. Study on the Enhancing Effect of Polyporus Polysaccharide, Mycobacterium Polysaccharide and Lentinan on Lymphokine-activated Killer Cell Activity in vitro. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. Apr1996;16(4):224-26.
20. Li KR, et al. Anti-atherosclerotic Properties of Higher Mushrooms (a Clinico-experimental Investigation. Vopr Pitan. Jan1989;1:16-19.
21. Shouji N, et al. Anticaries Effect of a Component From Shiitake (An Edible Mushroom). Caries Res. Feb2000;34(1):94-98.
22. Levy AM. Eosinophilia and Gastrointestinal Symptoms After Ingestion of Shiitake Mushrooms. J Allergy Clin Immunol. May1998;101(5):613-20.
23. Zjawiony JK. Biologically active compounds from Aphyllophorales (polypore) fungi. J Nat Prod. 2004 Feb;67(2):300-10.
24. Oliva D. Cellular and physiological effects of Ganoderma lucidum (Reishi). Mini Rev Med Chem. 2004 Oct;4(8):873-9.
25. Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem. 2000 Jul;7(7):715-29.
26. Borchers AT, Stern JS, Hackman RM, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med. 1999 Sep;221(4):281-93.
27. Mau JL, Lin HC, Chen CC. Antioxidant properties of several medicinal mushrooms. J Agric Food Chem. 2002 Oct 9;50(21):6072-7.
28. Hirasawa M, Shouji N, Neta T, Fukushima K, Takada K. Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing. (Shiitake, an edible mushroom). Int J Antimicrob Agents. 1999 Feb;11(2):151-7.
29. Rajewska J, Balasinska B. Biologically active compounds of edible mushrooms and their beneficial impact on health. Postepy Hig Med Dosw (Online). 2004 Oct 5;58:352-7.
30. Chang R. Functional properties of edible mushrooms. Nutr Rev. 1996 Nov;54(11 Pt 2):S91-3.
31. Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov;25(11):1387-95. PMID: 15525457
32. Cheung NK, Modak S, Vickers A, Knuckles B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol Immunother. 2002 Nov;51(10):557-64. Epub 2002 Sep 20. PMID: 12384807
33. Shamtsyan M, Konusova V, Maksimova Y, Goloshchev A, Panchenko A, Simbirtsev A, Petrishchev N, Denisova N. Immunomodulating and anti-tumor action of extracts of several mushrooms. J Biotechnol. 2004 Sep 30;113(1-3):77-83. PMID: 15380649
34. Zhang YD, Shen JP, Zhu SH, Huang DK, Ding Y, Zhang XL. Effects of astragalus (ASI, SK) on experimental liver injury Yao Xue Xue Bao. 1992;27(6):401-6. Chinese. PMID: 1442065
35. Sheng BW, Chen XF, Zhao J, He DL, Nan XY. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Chin Med J (Engl). 2005 Jan;118(1):43-9. PMID: 15642225
36. Yesilada E, Bedir E, Calis I, Takaishi Y, Ohmoto Y. Effects of triterpene saponins from Astragalus species on in vitro cytokine release. J Ethnopharmacol. 2005 Jan 4;96(1-2):71-7. PMID: 15588652
37. Li C, Cao L, Zeng Q. Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors' expression. J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):379-84. PMID: 15587404
38. Wang SH, Wang WJ, Wang XF, Chen W. [Effect of Astragalus polysaccharides and berberine on carbohydrate metabolism and cell differentiation in 3T3-L1 adipocytes]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Oct;24(10):926-8. Chinese. PMID: 15553830
39. Shao BM, Dai H, Xu W, Lin ZB, Gao XM. Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun. 2004 Oct 8;323(1):133-41. PMID: 15351712
40. Mao SP, Cheng KL, Zhou YF. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Feb;24(2):121-3. Chinese. PMID: 15015443
41. Guo FC, Williams BA, Kwakkel RP, Li HS, Li XP, Luo JY, Li WK, Verstegen MW. Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poult Sci. 2004 Feb;83(2):175-82.



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