Search Term: " Ineracion "

	Probiotics and Mood Enhancement: The Power of Lactobacillus Reuteri and Oxytocin	Darrell Miller	1/29/25
	six top-notch supplements that can help you achieve your goals.	Darrell Miller	12/6/23
	Could quercetin be the answer to your allergies?	Darrell Miller	4/30/22
	Reduce Inflammation Through Diet: Foods to Eat and Avoid	Darrell Miller	4/30/22
	Magnesium and vitamin D: The perfect pair?	Darrell Miller	4/24/19
	3 Ways to Boost Your Endocannabinoid System (Without Cannabis)	Darrell Miller	12/6/18
	CBD oil reduces chronic illness pain	Darrell Miller	7/30/18
	Cannabinoid-Pharmaceutical Interactions: What You Need to Know	Darrell Miller	2/17/18
	Treating Autism With Cannabis Now Has Scientific Support	Darrell Miller	10/20/17
	Four good reasons to keep oil of oregano around at all times	Darrell Miller	7/20/17
	6 Health Benefits Of Maca	Darrell Miller	6/13/17
	30 ways to boost your heart health	Darrell Miller	1/23/17
	Antioxidants- How To Fight With The Free Radicals	Darrell Miller	1/4/17
	What Are Glycosaminoglycans (GAGs) And What Herbs Contain Them?	Darrell Miller	7/21/15
	What Is GMO and Why Should We Avoid It?	Darrell Miller	6/21/14
	Can 5-HTP Help with Sleep?	Darrell Miller	5/26/14
	Why Is George's Aloe Vera By Warren Labs Better Than Other Brands?	Darrell Miller	1/10/13
	What Is Monolaurin And What Are Its Health Benefits?	Darrell Miller	12/29/12
	lycopene	Darrell Miller	11/12/12
	What Makes St Johns Wort Good For Depression And Anxiety?	Darrell Miller	9/18/12
	What is the History and Health Benefits of Pycnogenol?	Darrell Miller	3/24/12
	What are the Health Benefits of Oligonol?	Darrell Miller	3/23/12
	Guggul, Cholesterol and Your Health!	Darrell Miller	2/11/12
	What Are The Different Types Of Ginseng And What Is Ginseng Good For?	Darrell Miller	12/16/11
	Can Apple Cider Vinegar Help With Cholesterol And Triglycerides?	Darrell Miller	12/5/11
	What Makes Vectomega The Better Fish Oil Choice?	Darrell Miller	10/20/11
	What Makes Phytoestrogen So Good For PMS?	Darrell Miller	10/18/11
	What Are The Cruciferous Vegetables With Indoles?	Darrell Miller	10/18/11
	Can Saw Palmetto Out Perform Synthetic Treatments For Enlarge Prostate?	Darrell Miller	10/3/11
	Can Alpha GPC Really Help With Memory And Growth ?	Darrell Miller	9/29/11
	Can I Use Senna Leaves As A Laxative Daily?	Darrell Miller	9/27/11
	How Does Taurine Help the Brain?	Darrell Miller	5/13/11
	How Does Zinc Boost the Immune System and What Else Does this Mineral Do	Darrell Miller	5/2/11
	How Does Boswellia Fight Inflammation?	Darrell Miller	4/13/11
	Can Butterbur Help Me with Migraines	Darrell Miller	4/2/11
	Why is It so Important to Give Your Child a Multiple Vitamin Mineral Supplement	Darrell Miller	3/11/11
	How Does the Herb Holy Basil Help with My Health?	Darrell Miller	3/10/11
	Did You Know without Magnesium, You Could not Survive?	Darrell Miller	2/16/11
	Bromelain Supplements why?	Darrell Miller	11/6/10
	Clantro (Coriander Plant) to remove heavy metals	Darrell Miller	11/5/09
	Sarsparilla	Darrell Miller	7/31/09
	Colostrum	Darrell Miller	6/18/09
	Boswellia Extract	Darrell Miller	6/11/09
	Hoodia	Darrell Miller	1/29/09
	Control Blood Sugar Naturally	Darrell Miller	10/1/08
	Garcinia Cambogia	Darrell Miller	7/8/08
	B Vitamin Complex	Darrell Miller	6/23/08
	Chromium Picolinate	Darrell Miller	6/17/08
	Coral Calcium	Darrell Miller	5/16/08
	Copper	Darrell Miller	5/15/08
	Grapefruit Seed Extract	Darrell Miller	5/6/08
	Benfotiamine A Natural Solution Or Miracle Substance To Control Blood Sugar?	Darrell Miller	2/19/08
	Seniors Need More Than a Multiple with Only 100 Percent of the RDA	Darrell Miller	1/21/08
	Give Your Health A Boost With Silica Hydride A Powerful Antioxidant	Darrell Miller	1/18/08
	Natural Hormone Balance for Women	Darrell Miller	12/25/07
	Looking For A Calcium But Not Sure Which Is Best For You?	Darrell Miller	11/2/07
	Natural Vitamin and Herbal Alternatives For Joint Health	Darrell Miller	10/18/07
	Scientific Method of Evaluating the Effectiveness of Natural Medicines	Darrell Miller	4/21/07
	Peppermint Oil for IBS	Darrell Miller	3/24/07
	Revita	Darrell Miller	3/8/07
	Are there negative interactions with medicine?	Darrell Miller	2/27/07
	<B>Pycnogenol: Heart, Blood Sugar and Cellular Health</B>	Darrell Miller	11/3/06
	Benefits of Best Alpha Lipoic 35!	Darrell Miller	2/12/06
	Coenzyme Q10 and Cardiovascular Health.	Darrell Miller	12/13/05
	Butterbur Extract Fact Sheet	Darrell Miller	12/8/05
	TMG Fact Sheet	Darrell Miller	12/7/05
	Allibiotic CF Fact Sheet	Darrell Miller	12/7/05
	Benefits of Alpha Lipoic Acid	Darrell Miller	10/13/05
	Sytrinol can lower Cholesterol by 27% - 34%	Darrell Miller	9/20/05
	Source Naturals - Scientific Formulation	Darrell Miller	8/20/05
	Strontium Bone Maker 60 VC - Strengthen Bones	Darrell Miller	7/27/05
	Fight Hay Fever - Help Your Sinus...	Darrell Miller	7/11/05
	Quercetin and Bromelain - for better health.	Darrell Miller	7/4/05
	Echinacea - Choosing The Ideal Immune Support	Darrell Miller	6/30/05
	REFERENCES	Darrell Miller	6/25/05
	Herbal Forms	Darrell Miller	6/25/05
	RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available	Darrell Miller	6/24/05
	VANADIUM W/CHROMIUM - Supports Healthy Blood Sugar Levels	Darrell Miller	6/24/05
	GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....	Darrell Miller	6/21/05
	7-Keto - The Key to Healthy Aging	Darrell Miller	6/21/05

Date: January 29, 2025 10:41 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Probiotics and Mood Enhancement: The Power of Lactobacillus Reuteri and Oxytocin

Unlocking the Benefits of Lactobacillus Reuteri 2.5 Billion by Now Foods

Probiotics have gained considerable attention for their ability to support gut health and overall well-being. Among the many probiotic strains, Lactobacillus reuteri stands out not only for its digestive benefits but also for its unique ability to stimulate the production of oxytocin. Now Foods Lactobacillus reuteri 2.5 Billion offers a targeted and effective way to harness these advantages. Let’s explore the fascinating connection between probiotics, oxytocin, and the wide-ranging benefits this “feel-good” hormone offers.

What Is Oxytocin and Why Does It Matter?

Oxytocin, often referred to as the "love hormone," is a powerful molecule released in the brain that promotes feelings of bonding, trust, and emotional connection. It plays a vital role in childbirth, breastfeeding, and even in fostering social interactions. However, oxytocin isn't just limited to emotional well-being—it impacts physical health in surprising ways.

By regularly consuming Now Foods Lactobacillus reuteri 2.5 Billion, you can naturally boost your body's oxytocin levels. This is because the probiotic strain Lactobacillus reuteri has been shown in research to stimulate the production of this hormone. But what does that mean for your overall health? Let's take a closer look.

The Physical and Emotional Benefits of Oxytocin

Increasing your oxytocin levels can have remarkable effects on your health. Below is a breakdown of some of the most notable benefits:

1. Improved Stress Levels and Mental Clarity

Oxytocin helps reduce cortisol levels, the body’s primary stress hormone, creating a calming and relaxing effect. Lower stress levels mean better focus, fewer mood swings, and improved mental clarity, which can significantly enhance your quality of life.

2. Enhanced Heart Health

Oxytocin contributes to cardiovascular health by reducing blood pressure and promoting anti-inflammatory effects on the heart. This hormone supports a healthy circulatory system and reduces the risk of heart-related diseases.

3. Stronger Relationships and Social Connections

By fostering feelings of trust and empathy, oxytocin plays a crucial role in building and maintaining relationships. Whether it’s with family, friends, or your partner, increased oxytocin leads to stronger bonds and deeper emotional connections.

4. Pain Relief and Healing

Research indicates that oxytocin has natural pain-relieving properties. It can alleviate headaches, muscle pains, and even chronic conditions by acting as a natural analgesic. Furthermore, oxytocin promotes cellular repair and wound healing, enabling the body to recover faster.

5. Better Sleep

Higher oxytocin levels can improve sleep quality by calming the nervous system and reducing anxiety. This means you’ll wake up feeling more refreshed and energized to take on your day.

6. Boosted Digestive Health

Oxytocin complements the role of probiotics in supporting overall digestive wellness. With Now Foods Lactobacillus reuteri 2.5 Billion, not only will your gut be balanced and healthy, but your body will also benefit from the additional oxytocin-boosting effects.

How Does Lactobacillus Reuteri Help Produce Oxytocin?

Lactobacillus reuteri works within the gut microbiome to stimulate pathways that lead to oxytocin production. Studies suggest that this strain interacts directly with the vagus nerve—the nerve that connects the gut to the brain—reinforcing the mind-body connection. This explains why Lactobacillus reuteri isn't just good for digestive support, but also for mental and emotional health.

What sets Now Foods Lactobacillus reuteri 2.5 Billion apart is its high-quality formulation designed to ensure maximum potency and effectiveness. Each capsule delivers 2.5 billion viable organisms, formulated to survive harsh stomach acids and reach your intestines where they are most effective.

Why Choose Now Foods Lactobacillus Reuteri 2.5 Billion?

Now Foods is a brand known for its commitment to quality, safety, and value. Their Lactobacillus reuteri 2.5 Billion product meets rigorous standards, ensuring you receive a pure, reliable probiotic supplement every time. This probiotic is non-GMO, gluten-free, and packaged to preserve potency, making it a trusted choice for health-conscious individuals.

Additionally, Now Foods has earned a reputation for transparency. They follow Good Manufacturing Practices (GMP) to ensure that every ingredient is of the highest quality, making their wellness products stand out in a crowded market.

Adding This Probiotic to Your Routine

Including Now Foods Lactobacillus reuteri 2.5 Billion in your daily routine is simple. For optimal results, take the capsule with a meal or as directed by your healthcare provider. Over time, you may notice improvements in your mood, digestion, and energy levels as oxytocin-boosting effects take hold.

A Perfect Match With VitaNet

When shopping for health supplements, purchasing from a trusted platform is key. VitaNet is a reputable source for high-quality wellness products, offering competitive prices and reliable customer service. By shopping on VitaNet, you can enjoy the benefits of Now Foods Lactobacillus reuteri 2.5 Billion with the confidence of knowing you’ve chosen a trustworthy supplier.

Elevate Your Health Today

Whether you’re looking to enhance your digestive health, improve your mood, or simply support your overall well-being, Now Foods Lactobacillus reuteri 2.5 Billion is a powerful addition to your wellness routine. Thanks to its oxytocin-boosting properties, this probiotic goes beyond basic gut support to deliver benefits that enhance emotional, physical, and mental health.

Take Action Today!

Don’t wait to experience these incredible benefits for yourself. Shop at VitaNet today and order Now Foods Lactobacillus reuteri 2.5 Billion to unlock better health and happiness. Your well-being starts with a single step—make it now.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6620)

Date: December 06, 2023 04:55 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: six top-notch supplements that can help you achieve your goals.

If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.

For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before.

Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level.

For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence.

In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select.

Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery.

Oxidation and Free Radical Damage

A fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases.

Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level.

As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup).

Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease

Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being.

So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully.

Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging.

While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively.

Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery:

Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results.

BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - leucine, isoleucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair.

Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery.

Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline.

Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health

Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results.

Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein.

Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health.

In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6591)

Date: April 30, 2022 10:34 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Could quercetin be the answer to your allergies?

It's that time of year again, when the sneezing and sniffling starts. Seasonal allergies can make life miserable for millions of people. But what if there was a natural way to lessen your symptoms? Quercetin, a flavonoid found in many plants, might be the answer.

What are seasonal allergies and what causes them?

Seasonal allergies, also known as allergic rhinitis, are a type of inflammation of the nose that occurs when the immune system overreacts to airborne particles such as pollen, dust, or mold spores. The most common symptoms include sneezing, runny nose, and itchy eyes. Seasonal allergies can occur at any time of year, but they are most common in spring and fall. There are a number of different factors that can contribute to seasonal allergies, including genetics, weather patterns, and air pollution. In addition, people who suffer from other conditions such as asthma or eczema are more likely to develop seasonal allergies. treatment for seasonal allergies typically involves avoiding triggers and managing symptoms with medication. In severe cases, allergy shots may be recommended. With proper management, people with seasonal allergies can enjoy symptom-free days.

What is quercetin and where can it be found?

Quercetin is a plant-based flavonoid that has been shown to have potent anti-inflammatory and antioxidant effects. It is found in many fruits and vegetables, including apples, onions, and berries. Quercetin supplements are also available. Studies have shown that quercetin can help to reduce the symptoms of allergies, such as hay fever and seasonal allergies. It does this by inhibiting the release of histamine, which is a chemical that triggers allergy symptoms. In addition, quercetin can help to reduce inflammation and swelling. For these reasons, it is often recommended as a natural treatment for allergies.

How does quercetin work to alleviate allergy symptoms?

Quercetin has a wide range of health benefits, including reducing inflammation and acting as an antioxidant. Quercetin also has the ability to block histamine, which is one of the main molecules involved in allergic reactions. When histamine is released, it causes the symptoms of allergies such as runny nose, watery eyes, and hives. By blocking histamine, quercetin can help to reduce these symptoms. In addition, quercetin can also help to reduce the production of inflammatory molecules such as cytokines. This helps to further reduce the symptoms of allergies and inflammation.

How much quercetin should you take to see results?

So, how much quercetin should you take to see results? Studies on quercetin supplementation have used dosages ranging from 500 mg to 1,000 mg per day to start and go up as needed. Generally, the higher doses are used to treat specific conditions, while the lower doses are more typically used for preventative purposes.

Are there any other natural remedies that can help with allergies?

There is no doubt that allergies can be a real nuisance, causing symptoms such as itchy eyes, sneezing, and skin rashes. While medications such as antihistamines are commonly used to manage these symptoms, there may be other natural remedies that can help as well. For instance, researchers have found that medicinal herbs such as nettle and astragalus may help to reduce inflammation associated with allergies. Additionally, changing your diet to include more antioxidant-rich foods may make you less prone to allergic reactions. Overall, while medications can be an important part of managing allergies, there are many other natural strategies that may be helpful as well. By incorporating a variety of these strategies into your treatment plan, you can hopefully minimize the impact of allergies on your life.

How can you reduce your exposure to allergens in your environment?

Allergens are substances that can trigger an allergic reaction in certain individuals. While different allergies manifest themselves in different ways, the main goal for anyone who is trying to reduce their exposure to allergens is to create a healthier environment for themselves and their loved ones. There are a number of tactics you can use to do this, starting with some simple steps that can be implemented at home. These include installing high-efficiency particulate air (HEPA) filters in your HVAC system, thoroughly cleaning surfaces and dusting regularly, and eliminating any indoor plants. Other steps involve avoiding exposures outside of the home, such as limiting time spent in dusty places like construction sites or opting to stay indoors on high-pollen days during allergy season. Overall, by making a few small changes to your lifestyle, you can greatly reduce your risk of exposure to allergens and take back control of your health.

Can allergy medication be safely taken while taking quercetin supplements?

Many people experience the unpleasant symptoms of allergies, such as a runny nose, coughing, or itchy eyes. Fortunately, there are many different medications that can help to relieve these symptoms and allow you to live a more comfortable life. However, for some people, allergy medication does not provide adequate relief. In this case, taking quercetin supplements may be an effective alternative. Additionally, some research has suggested that quercetin may actually enhance the effects of allergy medication. So is it safe to take allergy medication while taking quercetin supplements? The answer is yes, but quercetin can affect the way certain medications are absorbed by the body and should never be taken without consulting a medical professional. By doing so, you can safely reap the benefits of both treatments and enjoy a more comfortable life free from pesky allergies.

The quick answer

Allergy sufferers often have to contend with a host of different symptoms, from itchy eyes and a runny nose to sneezing fits and anxiety. While there are a variety of over-the-counter medications available to provide relief, many people are hesitant to take them on a regular basis due to concerns about side effects. Quercetin is a natural compound that has been shown to be effective in reducing allergy symptoms. It is generally considered safe to take quercetin along with other over-the-counter allergy medications. While there is always the potential for interactions between different substances, quercetin and most over-the-counter allergy medications are unlikely to cause any problems when taken together. As always, it is best to speak with a healthcare professional before starting any new medication regimen while consuming natural vitamin and herbal supplements.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6403)

Date: April 30, 2022 10:02 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Reduce Inflammation Through Diet: Foods to Eat and Avoid

Do you suffer from inflammation? If so, you're not alone. Inflammation is a common problem that many people deal with on a daily basis. It can cause pain and discomfort in the body, and it can make everyday activities difficult to perform. Luckily, there are ways to reduce inflammation through diet. We will discuss the foods that you should eat and avoid if you want to reduce inflammation. We will also provide some helpful tips for getting started!

How can you reduce inflammation through diet?

There are many ways to reduce inflammation through diet, but perhaps the most important is cutting out processed foods and sugar. These foods contain inflammatory compounds known as advanced glycation end products (AGEs), which can aggravate existing inflammation or cause it to develop in the first place. In addition, studies have shown that eating a diet rich in vegetables and lean proteins can help to lower levels of inflammation throughout the body. Choosing whole grains, fruits, and healthy fats like olive oil is also a good way to support a body that is fighting against inflammation. In short, adopting a diet low in sugar and processed foods and high in fruits, vegetables, and lean protein can go a long way toward reducing inflammation both now and in the long term.

Supplements to take to reduce inflammation?

Inflammation is a natural and necessary part of our immune response, but if it becomes chronic or extreme, it can cause issues for our overall health. There are many different supplements that have been shown to be effective in reducing inflammation and promoting overall good health, including omega-3 fatty acids, Boswellia, pumpkin seeds, and turmeric. These nutrients work by interfering with the production of inflammatory hormones and enzymes, changing the chemical balance within our bodies and helping to reduce swelling and discomfort. Whether taken as a capsule or added to your diet through food sources like fish oil or ginger tea, these supplements can be an excellent way to boost your system's ability to fight inflammation. So if you're looking for ways to reduce inflammation and improve your overall well-being, consider adding these key nutrients to your daily routine.

The most effective anti-inflammatory supplements, Fish oil, Curcumin, and Boswellia!

While there are a number of different anti-inflammatory supplements on the market, some have proven to be more effective than others when it comes to reducing inflammation in the body. Perhaps the most commonly recommended supplement for this purpose is fish oil, which is rich in Omega-3 fatty acids, a type of polyunsaturated fat that has been shown to be especially effective in reducing inflammation. Another popular anti-inflammatory supplement is curcumin, which gives turmeric its signature yellow color and is thought to have antioxidant and anti-inflammatory properties. Additionally, another powerful anti-inflammatory agent is derived from the resin of Boswellia trees called Boswellia extract. All of these compounds have been shown to reduce inflammation in various scientific studies and can therefore be considered among the most effective anti- inflammatory supplements available today.

Tips for getting started on a anti-inflammatory diet?

When trying to get started on an anti-inflammatory diet, there are a few key strategies that can help make the process more successful. First, it is important to stock your pantry and fridge with plenty of healthy foods like fruits, vegetables, lean proteins, nuts, seeds, and reduce refined sugar intake as much as possible. These nutrient-dense foods are packed with essential vitamins and minerals that help to reduce inflammation and promote overall health.

Another key strategy to keep in mind when starting an anti-inflammatory diet is the use of supplements such as curcumin and CBD. These powerful compounds are believed to have anti-inflammatory effects in the body, helping to curb inflammation at its source vs. simply masking symptoms with painkillers or steroids. You can incorporate these supplements into your diet by taking them as pills or liquids or by incorporating them into your cooking through recipes like curried chicken or infused coconut oil tinctures.

The latest for calmness, relaxation, and to fight inflammation is CBD

CBD, or cannabidiol, has become increasingly popular in recent years as a natural solution for relieving stress, promoting relaxation, and managing inflammation in the body. Unlike THC, which is the psychoactive compound found in cannabis, CBD does not produce any high or altered state of consciousness. Instead, its many benefits are achieved through interactions with various receptors throughout the body, modulating mood and regulating pain response. As more and more people turn to CBD to achieve a sense of calm and well-being without depending on traditional pharmaceuticals, this powerful compound continues to gain widespread attention as a promising treatment option for everyday health issues. So if you're looking for a natural way to feel more mellow and at peace with yourself and your environment, consider giving CBD a try! With proven effects on everything from chronic pain management to improved sleep quality, this powerful all-natural remedy has something to offer everyone. Whether you're ready to give CBD a try for yourself or just curious about its many potential benefits, there's never been a better time than now to learn more about this exciting new approach to health and wellness.

Inflammation is one of the most common health concerns today, affecting people of all ages and backgrounds. While diet and lifestyle can be major contributing factors like white sugar, there are also a number of dietary supplements that can help to reduce inflammation in the body. Curcumin, fish oil, and CBD are some of the most popular supplements for managing inflammation. These substances work by targeting key pathways involved in inflammatory responses, helping to prevent or reduce swelling and pain. They can be taken on their own or combined with other anti-inflammatory compounds for maximum effectiveness. Ultimately, whether you are trying to manage chronic illness or simply boost your overall health, using supplements such as curcumin, fish oil, and cbd can be a great way to go about it. So if you're looking for more tools to manage inflammation in your diet, these are certainly worth trying out.

Whatever methods you choose, remember that making small changes over time will be much more effective than trying to overhaul your lifestyle all at once. With a little patience and persistence, you can start down the path toward better health today! Let dietary supplements assist you in your goal to reduce inflammation each day for a life time!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6402)

Date: April 24, 2019 01:49 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Magnesium and vitamin D: The perfect pair?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6171)

Date: December 06, 2018 10:16 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 3 Ways to Boost Your Endocannabinoid System (Without Cannabis)

Leaf Therapeutics is a Trusted product from Solaray, never consume off brands stay with quality!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5875)

Date: July 30, 2018 01:53 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD oil reduces chronic illness pain

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5683)

Date: February 17, 2018 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cannabinoid-Pharmaceutical Interactions: What You Need to Know

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5532)

Date: October 20, 2017 10:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Treating Autism With Cannabis Now Has Scientific Support

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5352)

Date: July 20, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Four good reasons to keep oil of oregano around at all times

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5004)

Date: June 13, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 6 Health Benefits Of Maca

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4823)

Date: January 23, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 30 ways to boost your heart health

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3819)

Date: January 04, 2017 10:37 PM
Author: Darrell Miller
Subject: Antioxidants- How To Fight With The Free Radicals

Free radicals are of good concern to any individual who wants to stay healthy. You have possibly heard of how hazardous these substances are and how essential are antioxidants that battle them. Understanding free radicals involves mastering just a little bit about their chemical background. Your body is made up of numerous connected parts. The organs and tissues that form these parts are all made from cells. In original terms, each cell is an independent unit that processes its waste and ingests nutrients, additionally to performing several other functions.

The Chemistry That Drives Our Cells

Chemical Reactions: All About Charge

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3743)

Date: July 21, 2015 08:53 PM
Author: Darrell Miller
Subject: What Are Glycosaminoglycans (GAGs) And What Herbs Contain Them?

Glycosaminoglycans refers to a linear unbranched polysacharide chain molecule composed of disaccharides repeats with a high negative charge due to the presence of Uronic acid components and sulfate esters with some hydoxyl (OH) groups as part of its structural components. They have varying molecular size and sulfation depending on the tissue they are located on and their state. They function to attract cations and maintain the hydration of the extracellular membrane (E.C.M).

Glycoaminoglycans are classified into different groups based on different categories which include; glycosidic linkages in their structure, type of the sugar moiety, sulphate groups numbers and the location of the sulfate groups. Based on this various classification categories six major groups of GAGs exists, namely; heparin, hyaluronan, dermatan sulfate, heparin sulfate, chondroitin sulfate, and keratan sulfate.

GAGs have a high solvation degree and and are as well highly viscous. This is beneficial to the body in that it helps to cushion and lubricate various connective tissues and body joints respectively. It therefore protects an individual from joint pains due to poor lubrication of the joints causing the bone to slide over each other. They also form the building blocks of proteoglycans which are the major building blocks of the extracellular matrix. Due to this property they are vital in determining the cellular activities such as cell division because the cell division machinery has to attach itself to the extracellular matrix before the division process is initiated. Some body tissues such as the nerve cells and the muscle cells require continuous cell division to replace worn out cells for the normal functioning. This means that structural deformities in the extracellular matrix will hinder the division process to occur and is most likely to lead to some neurodegenerative complexions.

Recent studies have linked GAGs to play a role in the cell biology of cancer.They have been established as the key macromolecules affecting cell properties and functions through interaction with key growth factors or by acting directly as receptor molecules. Through this it has been findings they play a vital role in the cell signaling process thus playing a role in the cancer disease progression.Heparin and heparin sulfate have been indicated through studies to have anti-tumor effects by preventing the process of angiogenesis which is the first step in cancer metastasis.Some have been associated with anti-coagulant properties.

Therefore GAGs are important molecules which play a vital role in protection against various forms of cancers. GAGs aremostly obtained from animal sources. The animal sources include shark fish and ray skeletons. Plants are also sources of GAGs, however their digestion by the human system is not possible. Seaweed is one herb that is rich in GAGs. However as earlier explain the digestion of the sea weed by the animal digestive system is quite a challenge. It is therefore recommended that we eat foods rich in proteins, and carbohydrates which can be used to synthesize GAGs in the body.

In summary, GAGs are heteropolymers which acts as the building blocks of the extracellular matrix in animals. The body has the ability to synthesize GAGs naturally hence nutritional supplement is required for the body to obtain key components necessary for the synthesis.
links

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3178)

Date: June 21, 2014 02:40 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is GMO and Why Should We Avoid It?

Cause of GMO

GMO's have been classified by the American Academy of Environmental Medicine as unhealthy, they were able to prove that GMO when ingested can cause organ damage, gastrointestinal as well as immune system disorders. This is due to the fact that GMO contains materials that are left behind the body, it can cause long term problems like accelerated aging as well as infertility. The genes inserted into a genetically modified crop like corn, can get transferred into the DNA of bacteria that is living inside the human body, this interaction can lead to a number of long term health problems.

Negative effects of genetically modified products have been observed in 1996, this was due to the number of Americans expressing a number of illnesses after consuming foods that have been engineered for 9 years.

Allergies increased including digestive problems and autism, while other research has yet to support this claim, many non-profit organizations such as Greenpeace are already making campaigns against the production of GMO infused crops and meat.

What are the other negative impacts of GMO?

1. Cancer causing components - GMO according to the American Public Health Association and American Nurses Association, have stated that the growth hormone present from cow’s milk treated by hormone IGF-1 can lead to cancer.

2. Long term negative effects on the body - GMO components can contaminate forever, it can cross pollinate, and the seeds can travel. Once it infects a certain area, it can contaminate the entire gene pool. This means, that the health of future generations is already compromised and for this reason, the production has to be stopped right away before it infects more population.

3. Dangerous side effects - the mere process of creation of GMO's can produce toxins, carcinogens, allergens and nutritional deficiencies.

The direct production and consumption is already endangering a number of species including bees.

Many governments continue to remain lax about the issue, GMOs are illegally being sold and created in many countries, and people need to learn as much as they can in order to learn how they can prevent GMO products from entering their market.

Sources

//www.responsibletechnology.org/10-Reasons-to-Avoid-GMOs

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3138)

Date: May 26, 2014 12:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can 5-HTP Help with Sleep?

What is 5-HTP

5-HTP (5-Hydroxytryptophan) is a compound which is produced naturally in the body via the means of the amino acid tryptophan. Even though this compound is already present in the body, researchers have found that we can benefit by having more of it. This has resulted in several supplement companies producing this compound from the seeds of an African plant known as Griffonia simplicifolia; 5-HTP can now be found in many health food and drug stores.

Benefits of 5-HTP

Even though there still hasn't been much research done regarding this supplement, we can still see that there are many uses for it. However, there is sufficient evidence out that shows 5-HTP is effective in treating depression and fibromyalgia, which means improved mood, reduced pain, better joint health, and better quality of sleep. To elaborate on the sleep benefits, 5-HTP increases serotonin levels which are converted into melatonin (a hormone which helps keep sleep cycles under control) through the body. There is also some evidence to suggest that this supplement can reduce anxiety as well as help promote weight loss in obese people.

So there is some great evidence to suggest that this supplement can help to improve our mood, quality of sleep, health and much more. However there is a slight downside, because of the limited amount of research done on this compound it is currently considered possibly unsafe to use. Potential side effects of 5-HTP include muscle ache/pain, heartburn, nausea, vomiting, drowsiness, stomach pain, and also a serious condition known as eosinophilia myalgia syndrome – a rare flu-like condition. Drug interactions can take place also; you should stay away from 5-HTP especially if you are taking any anti-depressant medication as these often increase serotonin levels which may result in too much serotonin in the body.

In conclusion

This supplement has many benefits and there has been research done to prove that it is effective in treating many problems such as insomnia, depression, fibromyalgia, anxiety, weight loss and more. However, it is recommended that you stay away from supplementing with 5-HTP because of the limited research done.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3125)

Date: January 10, 2013 12:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why Is George's Aloe Vera By Warren Labs Better Than Other Brands?

Since time immemorial, the succulent Aloe Vera plant has been an eminent medicinal plant with a worldwide recognition. The soothing effect, rejuvenating irritated membranes, moisturizing the skin and easing constipation have been some of the undisputed health benefits that makes Aloe Vera gel a worthy supplement and cosmetic product's constituent. Recent research also shows that Aloe Vera extracts have a notable efficacy in lowering blood glucose and blood lipid levels.

Studies however depict that the varied Aloe Vera species differ in some biochemical constituents and composition which makes some species better than others for a specific use. Georges Aloe Vera produced by Warren Labs specifically selects the species that are best suited for a given use. For instance, their George's Always Active Aloe Vera drink is made from Aloe barbadensis species which has been noted to be the most beneficial in rejuvenating mucal membranes that lines the GIT, effectively eases and prevents constipation without any irritation and also lowers blood lipid levels.

Unlike other manufacturing processes employed by other Aloe supplement producers, George's Aloe Vera employs fractional distillation method to obtain the most beneficial constituents and gives Georges Aloe Vera drink the characteristic clear and thin feel. This process is primarily intended to get rid of the Aloe Vera's aloins and anthroquinones which irritate the GIT manifested by cramping and diarrhea. The distillation process also makes the drink easy to preserve since most of the Aloe Vera's constituents which may necessitate special storage or addition of additives are discarded off.

This yields a pleasantly tasting drink with no additives or preservatives added. For optimal health benefits of this supplement, the manufacturer recommends a consistent daily intake of 2 ounces twice a day, and thus a gallon pack is always enough to use for a month. However, even though most of the Aloe Vera's constituents which produce considerable drug interaction implications are distilled off, consulting your doctor before using the supplement while under medication is always worthwhile.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2808)

Date: December 29, 2012 10:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is Monolaurin And What Are Its Health Benefits?

Get An Immune Boost:

Man has made a big leap as far as science and pharmacology are concerned, but there are still a lot of substances useful to human health that are waiting to be discovered. There are also those substances naturally occurring but whose pharmacological properties have not yet been explored. Monolaurin, for instance, is a naturally occurring substance whose use in human health has only been lately discovered.

Monolaurin, also called glycerol monolaurate and glyceryl laurate, is a 12-carbon fatty acid as well as a monoglyceride. Although it is a derivative of coconut oil, it is most commonly prepared as a lauric acid mono-ester. Aside from coconut milk, it is also present in human breast milk, which is known to function as an immune protection passed on from mother to child after childbirth. The potency of breast milk as an immune barrier is evidenced by the stunted growth and frequency of infections seen in infants deprived of breast milk. But, all this is old information.

What's new about monolaurin?

Known Uses of Monolaurin:

Before we get to new information, it's important to look into the discovery of monolaurin. Way back in the 1960's, then University of Detroit professor Jon Kabara made an important discovery - that the combination of lauric acid and glycerol can be used in fighting germs. First marketed as a dietary supplement called Lauricidin, it was soon marketed by other pharmaceutical companies, but Lauricidin remains its most potent and purest form.

Since its discovery, it has been used as symptomatic treatment (and prevention) for the common colds, flu, herpes, and many other infections.

Working similarly to breast milk, it helps protect the immune system from infections and other ailments. Some Lauricidin users also claim that the substance is useful against Chronic Fatigue Syndrome and even autism. As for viruses, it has proven to be a useful supplement against HIV, Measles, Herpes Simplex, Epstein-Barr Virus, and Cytomegalovirus, to name a few.

Studies:

Recent studies have shown its in vitro antibacterial and antimicrobial activity, at least as far as superficial skin infections are concerned. Carpo, Verallo-Rowell and Kabara (2007) demonstrated the effectiveness of monolaurin versus common antibiotics in battling both gram positive and gram negative infections such as Staphylococcus and Enterococcus. Older studies have explained Monolaurin's mechanism of action - it inserts itself into the cell membrane, disturbs the cell membrane integrity of Gram positive bacteria, and therefore blocks cell replication.

Aside from medicinal uses, it is also used for other purposes as well. It is a common ingredient in many deodorants, thanks to its antimicrobial activity; body odor, as you may know, is caused by the presence of certain bacteria. It is also present in other products such as shampoo, detergents, soap, and even in certain foods such as ice cream and margarine.

Side Effects and Drug Interactions

As far as side effects are concerned, there is still a lot to be known. Some users may experience the Herxheimer Reaction, a complicated term that indicates the presence of fatigue, body ache, irritability and fever that may worsen before the medication takes effect. Use during pregnancy and breast feeding is contraindicated, given that not enough is known about its potential effects during this period. Dosage ranges from 0.75 to 3 grams, 2 or 3 times a day, and is taken after meals.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2792)

Date: November 12, 2012 01:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: lycopene

Lycopene is a carotenoid that is responsible for the red color in melon, tomatoes, rosehip, guava and pink grapefruits. it is known to be highly antioxidant meaning that it is very effective in neutralizing free radicals which could damage the body cells. Since its discovery in 1964 by Alex R. Torres, it has been observed that this compound is easily absorbed in the body when processed into sauce, juice, ketchup and paste. When consumed in the body, this product is deposited in the lungs, skin, colon, prostrate glands and the liver. There are numerous health benefits that are associated with consuming lycopene.

Antioxidant benefits

Free radicals in the body pose a major health risk as they are likely to steel molecules from healthy cells thus causing damage. In fact, these radicals have been associated with the cause of majority of the cancer infections. It is a strong antioxidant and it is able to stop these free radicals from damaging healthy cells.

Heart benefits

Research has found that people who take products that contain lycopene regularly have reduced chances of getting heart diseases. It has also been observed that this compound can be used in the treatment heart diseases, osteoporosis, infertility and type II diabetes.

Anticancer benefits

It has been found to posses numerous anticancer benefits. The compound helps the body against DNA damage which usually happens during the development stages of cancer. One of the ways through which lycopene is able to achieve this purpose is by blocking the interactions of stromal cells and tumors cells.

When the interaction is interrupted, the tumor and stromal tissues are inhibited from growing and developing. It is an indisputable fact that lycopene is a very important component in our lives. It is for this reason that medical practitioners advice people to consume carotenoid foods especially the ones that contain lycopene.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2711)

Date: September 18, 2012 09:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes St Johns Wort Good For Depression And Anxiety?

St Johns wort

St Johns wort is a particular plant species. Firstly, in ancient Greek the medicinal uses of St Johns wort are recognized. It is an herb with yellow flowers. It contains active ingredients like flavonoids, anthrancenes, volatile oil and sugar alcohol which are used for medicinal purpose. St Johns wort binomial name Hypericum perforatum is also considered as wild plant, herb and weed. The other common names for this plant are Amber Touch-and-heel, goat weed, Klamath weed, Rosin rose and Tipton weed. As it is an herb its leaves and flowers are used for medicinal purpose.

What is St Johns wort?

St Johns wort is considered as a medicinal plant. It has yellow flowers which are used for medical purposes in various parts of the world. It is an herbal remedy to treat depression. This medicinal plant is also used for migraine, headache, muscle pain, chronic fatigue syndrome. It is also used for cancer and HIV/AIDS. St Johns is known as natural herbal remedy for mild to moderate depression. This highly valuable contains a chemical known as hypericin which effects against depression. This chemical act as mediatator in the nervous system which control the mood.

Does St Johns worth help depression? Depression has now become a common problem in humans now days. Due to the side effects of antidepressant medications, people are frequently moving towards natural remedies. St John wort is a complete health booster for the entire nervous system. It is recommended as a useful herbal remedy. It is scientifically proven that this particular plant is effective for mild to moderate depression. It has been used to treat mental disorders. St John wort is commonly used for depression and the conditions which are responsible depression such as anxiety, tiredness and sleep disorders. In most of the countries it is widely prescribed for depression. Wort is beneficial to people with mild depression but it is less effective on major depression.

St Johns wort medicinal properties:This medicinal plant is a powerful medicine.It is effective and well tolerated by the patients.You can feel yourself improving within the first week of usage of St John wort.As it is well tolerated by the patients, you can see fast results with fewer side effects.It decreases anxiety related to depression.It includes medicinal properties like antibacterial, anti inflammatory, antiviral, antidepressant and pain relieving.Traditionally it has been used to cure burns, headache, wounds, etc.

Though this is a powerful and remarkable medicine for treating mild to moderate depression, but still there is a question in the mind of health experts regarding major depression? In accordance with this, medicinal wort is less effective for the people who are taking other medications. St John wort is not effective on severe depression as discussed earlier. St John wort causes drug interaction so it might not be the right choice for the people who take other medication. You cannot ignore St Johns Wort, as it is a natural remedy for treatment of depression in spite of having few side effects.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2675)

Date: March 24, 2012 07:51 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is the History and Health Benefits of Pycnogenol?

What Are The Health Benefits Of Pycnogenol?

Pycnogenol is a name of a product which is prepared from a tree French Pine also known as French Maritime Pine. Pycnogenol is a trademark name sold as a nutritional supplement. This supplement is mainly used for asthma and a condition known as chronic venus insufficiency. It is a water extract of the bark of the French Pine found in the coastal south west of France. Pycnogenol contains unique flavonoid compounds in high concentration. These compounds at such high levels of concentration have proven to be useful and beneficial on inflammation, cancer, Alzheimer's disease, diabetes, erectile dysfunction, aging and healing of wounds.

History and Discovery of Pycnogenol:

Pycnogenol is a very powerful antioxidant made from a combination of natural antioxidants and phytonutrients. Since it is biologically made it is technically a bioflavonoid. A French scientist by the name Professor Masquelier gave the name Pycnogenol which is a scientific name for the oligomeric proanthocyanidins (OPCs) as well as other bioflavonoids. Pycnogenol is an extract from the French Maritime Pine and grape seed extract. Professor Masquelier along with a Swiss broker Horphag made attempts to commercialize Pycnogenol. Horphag without the consent of Masquelier registered the name Pycnogenol as a patent in the year 1990 which came under the ownership of Horphag in the United States. This caused severe legal disputes in the US. Horphag made huge profits from the intellectual property of Masquelier. This wonderful antioxidant was discovered by Jacques Cartier in 1953. In his books Cartier mentioned about the benefits of pine and how it cured and healed chronic diseases. Professor Masquelier discovered Cartier's book and recognized the benefits of these medicines which were rich in bioflavonoids.

Health Benefits of Pycnogenol:

Pycnogenol is a very powerful antioxidant which helps in regulating certain types of acids that gets absorbed in the human body through chemicals and free radicals. Antioxidants help in improving heart health and prevent cancer. Brain diseases like Alzheimer's can also be prevented with the use of Pycnogenol. It prevents the body from absorbing the toxic elements which are responsible for the development of brain diseases. It works as a good preventive tool. Pycnogenol also helps people who suffer from heart disease, which is a very common disease worldwide. It reduces swelling due to heart disease and helps in regulating the blood pressure. Pycnogenol also assists in reducing blood sugar levels in type ll diabetes, administered along with the anti-diabetes drugs.

Fight Inflammation

The anti-inflammatory and anti-oxidant properties of Pycnogenol are beneficial in treating asthma. It also improved the tolerance to chemotherapy in cancer patients. Pycnogenol works well as an anti aging product along with Vitamin E, and reduces wrinkles.

Pycnogenol is available in the market in different supplement formulas containing about 20mg to 100mg of Pycnogenol. It is the most extensively researched product and has also passed a number of safety tests. Tests have proved that consuming Pycnogenol at higher dosage for longer periods is safe though there are a few minor side effects. These side effects are gastro intestinal discomfort, nausea, dizziness and headaches. If consumed with certain drugs it can cause major side effects due to drug interactions. Pycnogenol is a great antioxidant supplement which helps in protecting and healing the body from harmful chemicals. Before taking Pycnogenol daily as a supplement it is recommended to consult physicians who can advice on the ideal dosages.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2616)

Date: March 23, 2012 08:12 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are the Health Benefits of Oligonol?

Oligonol

Oligonol is one of the few existing products in the market that has helped so many people so when one is asked what are the health benefits of Oligonol it's guaranteed that they won't fall short of words to say. This health supplement has anti-oxidant and anti-aging properties that help you achieve the best possible state of wellbeing. The following are some of the health benefits that you can get from using this natural supplement;

Improves blood circulation:Oligonol helps in improving blood circulation because it contains anti-oxidant elements that help in enhancing blood flow to the vital organs of the body.

Helps boost immunity: this health supplement fights against infectious bacteria and its agents and this is because it contains the lychee fruit which is a good source of vitamin C.

Helps reduce fatigue: in the research to find out what are the health benefits of Oligonol it was found that it helps speed up the body's recovery from fatigue after a period of physical exercises.

High energy levels: Helps increase energy levels in the body due to the fact that it helps facilitate the body's metabolic processes which in turn improves digestion.

Protects the body against cardiovascular diseases: when medical practitioners did a research on what are the health benefits of Oligonol, they found out that it contains minerals that include copper and potassium. These two minerals come from the lychee fruit. Potassium helps control a body's blood pressure and heart rate and for this reason protecting it from against diseases like strokes. On the other hand, Copper is important for the production of red blood cells in the human body. These blood cells are used to deliver oxygen to the body organs, tissues and muscles and without them the body would fail to function.

Reduces calorie levels and visceral fat production: use of oligonol health supplements helps reduce heart diseases risk that are brought about by visceral fat. Oligonol also contains elements that are rich in dietary fiber content and this helps control excess body weight.

Boosts memory: when asked what are the health benefits of Oligonol persons who had previously used the health supplement said it helped them remember stuff more easily than they did before they started using it.

Reduces stress levels: use of oligonol has proven to reduce peoples stress levels and it has been used as a remedy for depression as an added point to the research on what are the health benefits of Oligonol.

Inhibits production of influenza virus: previous studies gave sufficient proof that oligonol inhibits the production of the influenza virus by blocking the attachment of the virus to the body cells.

Improves skin: oligonol helps improve the skin appearance by reducing wrinkles and helping get rid of freckles on people's faces.

In addition, the oligonol health supplement is safe. This is because it is made from pure natural ingredients, and has no negative interactions therefore it can be used by all who would like to find out what are the health benefits of Oligonol and in turn benefit from it.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2615)

Date: February 11, 2012 07:53 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Guggul, Cholesterol and Your Health!

Guggul is a secretion substance, usually a yellowish rein, of the mukul myrrh tree botanically known as Commiphora mukul. It has been used for centuries now in the Indian Ayurvedic medicine as a remedy for conditions such as osteoarthritis, obesity as well as some skin conditions. Recent studies have also indicated that guggul can also be used to lower the levels of cholesterol mostly by inhibiting cholesterol synthesis and accelerating the removal of the LDL and triglycerides cholesterol. Besides lowering cholesterol and blood fats, guggulipid extracts have been observed to raise the level of HDL cholesterol ,which are good cholesterols, and thus enhancing the health of your heart by shielding it against artherosclerosis vascular disease.

The guggul extract contain a compound that inhibits the functioning of a receptor in the cell known as FXR. This receptor is responsible for regulating the cholesterol in our body by varying the amount of the bile acids in our bodies. Usually, cholesterol in our body is either from synthesis in the liver or from diet. Cholesterol is contained in the bile acids which are made in the liver before being passed to the gall bladder and then to the small intestines. They help in the metabolism of fat in the small intestines before reprocessing and returning to the liver. By preventing the functioning of the FXR receptor implies that more cholesterol becomes excreted. In so doing 14 to 27 percent of LDL cholesterol and 22 to 30 percent of triglycerides cholesterol levels are reduced with use of guggul without need for exercise or diet.

Since guggul is instrumental in hardening of the arteries (artherosclerosis) and maintaining gigh levels of HDL (High-density lipoprotein) it has been seen to be a remedy for male erectile dysfunction and impotence. Further, guggul enhances the function of thyroid gland which is responsible in production of hormones that regulate metabolism. This therefore aids in weight loss by altering the thyroid function to increase production of thyroxine metabolite, triiodothyroxine and T3 which enhances the general body metabolism and by extension enhance burning of fats.

The action of guggul thus creates a balance between low and high cholesterol which may be in our bodies owing to diet, chronic stress, genetic propensity and also lack of exercise. A number of studies have reported that it is a safe and effective remedy to improving and maintaining a ratio of HDL to LDL cholesterols. In addition to maintaining normal ranges of cholesterol levels, it shields you against heart disease and inflammation.

In research, guggul extracts has been observed to clash with CYP3A4 enzyme whose responsibility is to metabolise numerous chemicals in the body. CYP3A4 is also responsible for metabolism of medications and thus guggul use tends to reduce the effectiveness of a number of medications such as diltiazem, propanolol and birth control pills. However, it has been reported that it in fact increases the levels of certain drugs such as statins in the body resulting in an improved effectiveness. Another problem of guggul use is its ability to raise the effectiveness of blood thinners and hence blood clotting becomes a challenge and it results to excessive bleeding. Therefore guggul should be administered only in the event that one is not under medication or the interaction between guggul and the medication is in fact not detrimental.

Have your tried Guggul Today?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2570)

Date: December 16, 2011 06:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Different Types Of Ginseng And What Is Ginseng Good For?

Ginseng is a considered to be a perennial plant which is a member of the Panax genus under the family of Araliaceae. It is abundantly found in North America, East Asia and other places which have a cool climate. There are many types of ginseng. Though different in kind, all these species of ginseng contains the active ingredient known as ginsenosides. This chemical substance is the one responsible for the many health benefits of ginseng.

The types of Ginseng are:

1. PANAX GINSENG. This type of ginseng is also known as Asian ginseng. It is very rich in ginsenosides which proves that it is included among the types of true ginseng.

2. PANAX QUINQUEFOLIUS. This ginseng has an effective adaptogenic property. It is otherwise known as American ginseng. This herb is also considered as a true ginseng.

3. ELEUTHEROCOCCUS SENTICOSUS. The other name for this herb is Siberian ginseng. However, it is not considered as a true ginseng because it does not contain ginsenosides but eleutherosides. Also, ginseng has a fleshy root while this herb has a woody one. Despite their differences, Siberian ginseng also has similar effects to true ginseng herbs. It has an adaptogenic property which can effectively improve the overall health of the individual.

As mentioned above, ginseng has many benefits to human health. These include:

1. IMMUNE SYSTEM BOOSTER. Ginseng contains several vitamins and minerals which can be helpful in improving the immune system as well as the overall health of the individual. Studies have shown that ginseng has an ample amount of Vitamin C which can help maintain the health and strength of the body’s immune system. As a result, ginseng can effectively improve health especially those who are one the recovery phase of an illness.

2. LOWERS BLOOD GLUCOSE. Asian ginseng is noted for its potential ability to help regulate blood sugar levels. This is made possible because of its action in the stomach and intestine to control the absorption of glucose from the diet. In this connection, health experts highly recommend that individuals under diabetic therapy must use ginseng with extra care because it might cause hypoglycemia or low level of sugar in the blood.

3. AFFECTS BLOOD PRESSURE. Ginseng can produce an effect to the blood pressure of the individual, either high or low blood pressure. Depending on the dosage and the person’s response, ginseng can effectively maintain blood pressure within it normal limits.

4. IMPROVES THE OVERALL STATE OF HEALTH. Many ginseng consumers have reported that they experience an increased sense of well – being with their regular use of such helpful herb. It is also commonly used for the improvement of one’s stamina and endurance in performing many mental and physical tasks.

Ginseng can be consumed raw. Others use dried roots of this herb. Supplements are also available in the form of tablets, extracts and teas. Ointments and creams are also formulated for topical administration. If you plan to use ginseng for a particular health indication, make sure to talk to your doctor first since ginseng can have significant effect to the body as mentioned above. This will greatly prevent adverse effects and interactions with other medications you are taking.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2543)

Date: December 05, 2011 09:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Apple Cider Vinegar Help With Cholesterol And Triglycerides?

Apple Cider Vinegar And Cholesterol

Apple cider vinegar is yielded by mashing the fruit and squeezing out the juice it contains. Friendly microorganisms such as bacteria and yeasts are usually combined into the extracted juice to allow alcoholic fermentation. These microorganisms are the ones responsible for converting the sugar contained in the apple extracted juice into its alcohol form. Apple cider vinegar undergoes a second fermentation process. The alcohol produced from the first fermentation process is converted into its vinegar form by adding an ample amount of acetic acid – forming bacteria specifically known as Acetobacter. As a result, the juice extract will have a sour taste because of the acetic acid and malic acid it contains after several fermentations.

In the food industry, apple cider vinegar is commonly used as an ingredient of salads, marinades, food preservatives and the like. Aside from its acetic acid content, apple cider vinegar also contains amino acids, vitamins and minerals.

Clinical studies on whether apple cider vinegar can help control the amount of bad cholesterol and triglycerides in the blood have shown significant results. Yes, apple cider vinegar can have promising effects on the regulation of serum cholesterol and triglycerides. However, the studies also revealed that this fruit extract must not serve as a substitute for the medications prescribed by your doctor to regulate blood cholesterol and maintain or improve cardiovascular health. In animal studies, apple cider vinegar has shown positive effects on lowering triglycerides by almost 50 %. However, effects on Low Density Lipoprotein or the so – called “bad cholesterol” are not that efficient.

Needless to say, the American Heart Association stated that a good lifestyle and balanced diet can effectively reduce the amount of bad cholesterol and triglycerides in the blood. Apple cider vinegar will also greatly help in lowering these substances in the blood.

Other studies have also revealed that the acetic acid content in apple cider vinegar stimulates the expression of the genetic material which activates fatty acid oxidation enzymes. As a result of this biological process, there will be a significant lowering or control of body fat accumulation by the liver. This is the reason why apple cider vinegar can also be employed as a weight loss agent.

Apple cider vinegar is all – natural. Therefore, safety is relatively established. However, health experts still suggest that before you start using this product, you have to consult your doctor and discuss your current and past health condition as well as the other medications you are taking. This will reduce the incidence of adverse health reactions and drug to drug interactions.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2540)

Date: October 20, 2011 01:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Vectomega The Better Fish Oil Choice?

Fish Oil Whats Best?

Vectomega is an excellent supplement for individuals who do not acquire Omega-3 fatty acids in their daily regular meals. Some of its advantages are:

1. ALL NATURAL. This fatty acid supplement is completely all – natural. In addition, clinical studies revealed that it has the most level of natural oils in the commercial world of essential fatty acid supplements. This product has undergone a process which is patented and is free of synthetic chemicals. The process only utilizes natural enzymes and cold water as solvent.

2. INCREASED ABSORPTION RATE. Chemically, Vectomega has been found to be 50 times more absorbable than any other essential fatty acid supplements.

3. NO FISHY TASTE AND SMELL. Another advantage of this supplement is that though it is extracted from fish oils, it has no fishy aftertaste and won’t give you a breath smelling like you have just eaten fish for meal.

4. NO REFLUX. Unlike the other kind of fatty acid supplements, it cannot produce a disturbing gastric reflux after taking.

5. MORE SOLUBLE AND BIOAVAILABLE. It is also more soluble and is considered to be the most bio-available among the other fish oil supplements. It has been graded high in terms of active bioavailability among Omega -3 fatty acids under phospholipid reaction.

6. MORE PRACTICAL. It is a practical choice. One renowned pharmaceutical association stated that 2 tablets of Vectomega are equivalent to 12 to 16 capsules of another fish oil supplement.

7. ANTIOXIDANT. Not to mention, it is effective not only as essential fatty acid supplement but also an anti – aging agent because of its potent antioxidant property.

Vectomega have undergone many thorough clinical studies. It has been claimed to be safe and effective to supply the body with sufficient amount of essential fatty acids. However, health experts still suggest that it would be best and most safe to seek medical consultation first before starting supplementation. This would significantly prevent any untoward effects and abnormal interactions with other medications and supplements you are taking. The recommended dosage of this supplement is 2 tablets everyday for 30 days and then only one tablet daily for the next months and so on. However, if you wish, it is still safe to continue with 2 tablets per day for a more improved benefit.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2521)

Date: October 18, 2011 04:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Phytoestrogen So Good For PMS?

Phytoestrogens are considered as plant estrogens. These plant substances can function like the primary sex hormone Estrogen. This chemical compound is also known as "dietary estrogen" which is an assorted cluster of non - steroidal plant compounds. As earlier, Phytoestrogens comes from plants and not produced by the body like the naturally occurring estrogen. These chemicals are not made available to the body naturally but by food or vegetable consumption. Though their source is different, estrogen and Phytoestrogen closely resembles each other chemically. They almost have the same structure making Phytoestrogen compounds act like natural estrogen inside the body.

Chemically, Phytoestrogen is not considered as a nutrient because health experts declared that any lack of this chemical in the body would not produce any sign or symptom of deficiency. Also, this chemical substance does not have any involvement in any of the body’s vital biological processes. However, despite this fact, Phytoestrogen can be employed for the effective relief treatment of Post - Menopausal Syndrome or PMS.

The signs and symptoms of Post - Menstrual Syndrome is associated with the decreased concentration of female sex hormone such as estrogen in the body. As estrogen levels in the blood decrease, body discomforts such as hot flashes, night sweats, mood changes and irritability may become apparent. In this situation, Phytoestrogen can be helpful in relieving such uncomfortable signs and symptoms. Phytoestrogens can effectively bind to estrogen – receptor sites inside the boy thus falsely giving the body a signal that there is an adequate amount of estrogen. Phytoestrogens can effectively mimic the action of estrogen mildly but sometimes antagonize its effect. Many studies have revealed that adequate supply of Phytoestrogen can effectively alleviate the discomforts of PMS.

Other than it ability to bind with estrogen–receptor sites, Phytoestrogen also changes the amount of natural body estrogen by interacting with certain enzymes in the body. This interaction with several enzymes may increase the effect and bioavailability of endogenous sex hormones. Studies have also shown that Phytoestrogen can improve the synthesis of Sex Hormone – Binding Globulin which is the hormone responsible for the binding and use – up of sex hormones inside the body.

The plants which are rich in Phytoestrogens include a variety group of foods. Legumes, whole grains and seeds contains abundant amount of this chemical compound. Soy, wheat berries, fenugreek, lentils ginseng, apples, yams and carrots are also considered as good source of Phytoestrogens. This beneficial chemical compound was discovered first on red clover plant which is considered to be very rich in Phytoestrogen. Phytoestrogen is also formulated in the form of capsule, tablet or powder supplements. Health experts highly recommend that women on the menopausal stage must take only less than one milligram of Phytoestrogen supplement daily.

If you want to reduce symptoms of low estrogen, give phytoestrogen a try!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2515)

Date: October 18, 2011 02:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Cruciferous Vegetables With Indoles?

A cruciferous vegetable is a common category of vegetables. The term cruciferous is used to refer to vegetables which have a cross - shaped pattern that can be found under the core of the plant's stalk. This classification of vegetables includes:

1. CABBAGE. This vegetable is a common leafy green vegetable of the specie Brassica oleracea. It is an herb - like, biennial flowering plant which has a short stem with a jam - packed mass of leaves. The leaves are generally green to light green but variety comes in red or purple color. An immature cabbage has a characteristic compact and circular cluster of young leaves.

2. BROCCOLI. A kind of vegetable which is categorized in the Italica cultivar plant cluster. This is different from cabbage because it has large flower heads which is usually dark green in color. It is arranged in a small tree – like manner on branches which is sprouting from a solid edible stalk. This vegetable is similar to cauliflower, another cruciferous vegetable.

3. CAULIFLOWER. Like cabbage and broccoli, cauliflower is also a member of the species Brassica oleracea. Unlike cabbage, this cruciferous vegetable is an annual plant which is reproduced by seeds. The appearance of this plant is like that of a broccoli. The floral meristems are usually eaten only while the stalk and leaves are utilized in vegetable broths.

4. BRUSSEL SPROUTS. This is a cultivar of cabbage family which is cultivated because of it edible buds. It is named after the city in Belgium which is believed to be the origin of the vegetable.

Cruciferous has many health benefits. Aside from its fiber – rich content, cruciferous vegetables has a promising benefit of lowering the risk of cancers specifically with that of the colon, breast and prostate. The special chemical compound in cruciferous vegetables is called “Indoles”. Indoles are considered as a phytonutrient which can benefit the body in many ways.

Since the ancient times, Indoles have been used for many medicinal purposes. In fact, most Roman health practitioners during the olden times have utilized Indoles as treatment for ulcerated breasts. Therefore, without a surprise Indoles found in cruciferous vegetables are widely used for the prevention of breast cancer. Clinical studies have revealed that the mechanism of action of Indoles in relation with decreased risk of cancer is that Indoles can effectively decrease the so – called C16 estrogen and increase C2 estrogen. The latter is helpful in preventing the development of abnormal breast tissue growth or cancer.

Furthermore, Indoles have also been found out to have important benefit in detoxifying the body from free radicals, thus preventing the body from free radical damage and promoting a healthy cellular production and growth. Other theories have stated that Indoles in cruciferous vegetables can block carcinogenic chemical compounds from mutating the cell’s DNA and neutralize the effects of estrogen associated with cancer development.

Other vegetables which contain Indoles are onions and garlic. The Indoles component of these vegetables effectively works hand in hand with antioxidants in protecting the body from harmful substances and toxins.

Aside from these natural vegetables, Indoles chemical compound can also be made available to the body in the form cruciferous vegetable extracts. This supplement has adequate amount of balanced Indoles compound which can equate with the body’s daily recommended intake of Indoles necessary to fight against free radical damage and cancer. However, extra caution must be observed to prevent untoward side effects and unnecessary drug interactions.

Cut the calories, try Indoles in supplement form!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2514)

Date: October 03, 2011 02:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Saw Palmetto Out Perform Synthetic Treatments For Enlarge Prostate?

Saw palmetto is a tree type of plant which is scientifically known as Serenoa repens. It is abundantly found along the coast of southeastern part of USA. This plant bears flowers which comes in yellow and produces fruits which are berry - like and reddish black in color. Saw palmetto supplements are extracted from the plant’s berries. The berries are rich in fatty acids and phytosterols. Saw Palmetto berry extracts are made by drying the berry and mixing it with a solvent like hexane and ethanol.

Since the ancient times, Saw Palmetto has been long used as an edible food and an herbal plant. The most common use of this herb is for the improvement of benign prostatic hyperplasia or BPH. This illness usually results to problems with urination and sexual activity. The enlarged prostate may obstruct the flow of urine making urination difficult and even painful for some. It can also affect the individual’s sexual activity because the prostate is the gland responsible for producing seminal fluid which is a component of the male ejaculate.

The mechanism of action of this herb in improving the condition of benign prostatic hyperplasia is that it inhibits the action of the enzyme called 5 – alpha – reductase which is involved in the abnormal growth of the prostate gland. Another theory on its action in relation to benign prostatic hyperplasia is that it can effectively interfere with the chemical substance called dihydrytestosterone. One of the reasons of prostate enlargement is that there is increased amount of the hormone testosterone that binds to androgen receptor sites. Saw Palmetto extracts have been found to bind with androgen receptor sites and act as a phytoestrogen. Therefore, if the receptor sites are already filled up, testosterone hormones will not be able to attach to these receptor sites and provide an effect to the body. Hence, if testosterone is minimized, enlargement of the prostate gland will also be controlled.

Benign prostatic hyperplasia is a serious health condition. Several prescribed medications are available to treat this illness. Indeed, saw palmetto extracts may be helpful but this supplement must not be used as a substitute for your prescribed medications. It may have similar actions with BPH drugs such as Finasteride but its potency is different. Clinical studies have also revealed that saw palmetto supplements do not directly decrease the size of the prostate gland but the lining inside the gland. It thins the inside layer of the gland thus minimizing pressure that rests on the urine tubes or urethra.

Saw palmetto is generally safe. However, since it can cause significant changes inside the body, it is important that you should talk to your doctor first before using this supplement, most especially when you already have BPH. You have to consult your doctor and discuss with him or her about your current health status, past medical history, familial health history and other medications taken whether prescribed or not. Dosage of the supplement is also best determined by your doctor. This will greatly help in the avoidance of untoward effects and unnecessary negative interactions with the other drugs you are taking.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2473)

Date: September 29, 2011 11:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Alpha GPC Really Help With Memory And Growth ?

What Are The Benefits Of Alpha GPC?

L-Alpha Glycerylphosphorylcholine, or abbreviated as Alpha GPC, is a natural compound which is choline in nature. It is considered to be an acetylcholine precursor which is now being studied as a treatment for the degenerative disease called Alzheimer’s disease. This chemical compound also has a parasympathomimetic property and is widely used as a nutritional supplement for enhancing memory and concentration. The other name of Alpha GPC is Choline Alfoscerate. Alpha GPC has the capacity to rapidly transport choline to the central nervous system by passing through the blood - brain barrier. Alpha GPC can be extracted from highly distilled soy phospholipids such as lecithin. Inside the body, this chemical compound can be found in high quantity in neuronal membranes. Some of its benefits are:

1. IMPROVES ACETYLCHOLINE LEVEL. As mentioned earlier, Alpha GPC can cross the blood – brain barrier. Once inside the brain, it positively influences brain activity by enhancing the production of acetylcholine. Acetylcholine is a neurotransmitter which is responsible for improving the individual’s learning process. Acetylcholine acts on both the peripheral and central nervous system. In the former, this neurotransmitter functions as the main neurotransmitter in the autonomic nervous system. It is also involved in the contraction of body muscles. In the latter, acetylcholine acts as an anti – excitatory chemical in the cholinergic system.

2. MEMBRANE COMPONENT. Another health benefit of Alpha GPC is that it can effectively protect nerve cells thus improving the transmission of impulse. Aside from maintaining the integrity of the nerves and nerve cells, Alpha GPC also serves as a precursor of the phospholipids found on membranes.

3. INCREASE HUMAN GROWTH HORMONE. Studies on Alpha GPC have revealed that it can relatively influence the action of the body’s Growth Hormone – Releasing Hormone (GHrH), thus improving the release of growth hormones. In addition, it can also enhance the effects of human growth hormone especially among young individuals.

4. A MODALITY FOR DEMENTIA. Alpha GPC has been long studied for the treatment of senile dementia. Initial result of such studies revealed that patients supplemented with Alpha GPC showed improvement but on a smaller extent. Further studies are still being conducted so that efficacy and safety as well as the appropriate dosage will be determined.

5. INFLUENCES GABA. Studies reveal that Alpha GPC significantly increase the synthesis and release of Gamma Amino – Butyric Acid or GABA. Increased synthesis of GABA is also potentiated by atropine. GABA is considered as the principal inhibitory brain chemical among mammals. It has a significant role in controlling neuronal excitation all over the nervous system. Like acetylcholine, GABA is also one of the primary responsible chemicals for the control of muscle tone.

Alpha GPC is formulated as supplement. It is available in 300 to 1,200 milligram oral supplements. Though it is generally safe, it is important that you should consult your doctor first before using this supplement. This would significantly avoid the occurrence of adverse effects and drug interactions. Appropriate dosage will also be determined by your doctor. Remember, any medication or supplement varies from person to person on its therapeutic and adverse effects.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2468)

Date: September 27, 2011 12:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can I Use Senna Leaves As A Laxative Daily?

What Are Senna Leaves Good For?

Senna is a plant which belongs to the family of flowering plants known as Fabaceae. This plant can be abundantly found in tropical regions. This plant is considered to be a shrub. However, some seemingly looks like an herb or a small tree. Senna is one of the most commonly used herbal laxatives. Other names of Senna are Cassia Senna, Tinnevelly Senna, India Senna, Alexandrian Senna, and Khartoum Senna.

The active ingredients of Senna are called Anthraquinone and glycosides. As a laxative, the active chemical in Senna acts primarily on the large intestine, therefore, this herb has a promising effect in relieving constipation. Clinical studies have also reported that Senna can enhance peristaltic movement of the intestines. This is possible because of its irritating effect on the mucosal lining of the intestines.

To be specific, Senna is an effective laxative. It is categorized as a bowel stimulant or irritant. This type of laxative acts primarily on the mucosa of the intestines and stimulates the nerve plexus to influence water and nutrient absorption as well as reabsorption. This alteration will then lead to the stimulation of peristaltic activity of the bowel. Thus, digestive tract movement is increased and stool elimination is induced. However, this may not be safe under certain circumstances. For this reason, stimulant laxatives must be used cautiously and employed for a short period of time only. As a result, Senna can also be employed as one of the weight loss herbal agents.

Moreover, the leaf of Senna plant consists of essential oils which can potentially destroy harmful microorganisms that can cause skin irritations such as rashes, blisters and acne. In the traditional medicine, Senna leaves are prepared in the form of paste which is then applied on skin to treat ringworms and other skin infections.

In addition, another health benefit of Senna is its potent antioxidant property. According to chemical studies, Senna herb contains high amount of antioxidants. Antioxidants are important to the body because they help prevent diseases by way of eliminating harmful toxins from the body. One of these harmful chemicals is called free radicals. These kinds of substances occur naturally in the body as an end – product of biological reactions. Free radicals can cause interruption on cellular division by altering replication of DNA. Aside from that, it can also cause damage to healthy cells of the body, thus promoting illnesses and diseases.

With the several health benefits of Senna, it must not be employed as a substitute to prescribed medications. This herb is available in supplements. You can purchase this product in many health and drug stores or even Online. However, it must not be abused. More importantly, medical consultation must be done first so that adverse effects and untoward drug interactions will be avoided. Use Senna herbal supplement as labeled or prescribed. Like any other laxative, do not use this in large amount and for a longer period of time. This may cause dependence in which you cannot have a bowel movement without the use of such supplement or laxative.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2463)

Date: May 13, 2011 01:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Taurine Help the Brain?

Taurine is an amino acid often added to energy drinks. There have been several theories on how taurine affects brain chemicals and improve cognitive function. For many years, it has been compared to caffeine due to its effects on the human brain that appear to enhance mood. Its exact mechanisms of action remain a mystery to the scientific community, but recent studies are believed to be closing in.

It has long been known that taurine crosses the blood brain barrier, allowing it to exert some effects on several neurotransmitters found in the central nervous system. It has been tied to the alleviation of many mental illnesses, such as epilepsy, post traumatic stress disorder, clinical depression, bipolar disorder, and anxiety, making it the subject of a number of studies in the past few years.

Rebalances Brain Chemicals

It has been postulated that taurine influences the activities of neurotransmitters in the brain, but only recently has brain scientists been able to actually track its activities in the brain. A team of researchers at Cornell University managed to find a site for the neurological activity of taurine, with initial results pointing to its relationship with gamma the neurotransmitter aminobutyric acid, or GABA. The researchers do not discount the possibility that taurine may even have a receptor of its own.

Whether taurine interacts with brain chemicals is no longer debatable as it creates homeostasis in the central nervous system. It acts on receptors that the researchers discovered to be the same receptors present in GABAergic mechanisms. That being said, scientists remain inconclusive as to how its interaction with GABA receptors provides energy-boosting benefits as it is marketed in the food and drug industries.

Prevents Neuron Damage

The scientific community is convinced that taurine has neuroprotective properties. High levels of taurine in the brain have been observed to protect brain tissues from cerebral ischemia. Taurine has been linked to many metabolic pathways that are known to promote neurological health, such as the activation of glycine receptors and the regulation of enzymes called cysteine-dependent aspartate-directed proteases.

In addition, taurine serves as antioxidants that protect nerve cells from cellular damage brought on by oxidative stress. The presence of taurine within cells reduces damage from calcium excesses and increases mitochondrial events. For decades, supplementation of taurine has benefited sufferers of brain ischemia, epileptic seizures, panic attacks, anxiety symptoms, and even alcohol withdrawal.

Enhances Cognitive Function

Taurine has already been associated with physiological functions the hypothalamus controls, such as sleep-wake cycle and responses to fatigue. In several laboratory studies, administrations of taurine by way of intraperitoneal injection have successfully induced social interaction in animal subjects. It is one of the amino acids that affect cognitive development, especially in children. While it is one of the most abundant amino acids in the brain, it is depleted as we age, making supplementation a good option.

Protect your brain with Taurine by taking it daily!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2295)

Date: May 02, 2011 01:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Zinc Boost the Immune System and What Else Does this Mineral Do

Zinc And Good Health!

Zinc is considered a transition metal in general, and as such one of the most abundant transition metals in living organisms, including human beings. It plays a central role in the molecular structure of proteins, which is indispensable in catalytic activities of over a hundred enzymes. These proteins belong to all enzyme classes and have far-reaching effects on the human body, notably in the immune system.

In the past few decades, the scientific community has unearthed countless chemical reactions that take place inside the human body. A number of these reactions necessitate the presence of zinc. While zinc is considered toxic in high amounts, it is classified as an essential trace mineral, which means it has a daily value. A deficiency in zinc has serious effects on growth and development as implicated in the life cycle of cells.

Stabilizes Cellular Structures

Zinc is a trace mineral that is quite pervasive at the cellular level as all cells have zinc demands. This dietary element keeps cells in prime condition and maintains the health of cell organelles. For one, zinc is required to stabilize ions that functions as interaction modules responsible for binding DNA, RNA, and other particles found within cells. The absence of zinc in cells will cripple these activities.

The complete absence of this trace mineral is improbable, but low levels of elemental zinc in the body have been observed to have serious effects on cellular health. The capacity of cells to contain radical damage depends on the availability of zinc. Depleting levels of zinc result in an impaired antioxidant defense and greater susceptibility to free radicals and other reactive oxygen species.

Induces Enzymatic Reactions

Enzymes are proteins that play functional roles in the metabolism of bioactive compounds. They are categorized into many classes, depending on their catalytic functions. These functions are vital as they are one of the mechanisms in the employ of the body to sustain homeostasis. Some classes are involved in immune responses in the prevention of disease and the alleviation of chronic disorders.

All classes of enzymes are affected by the metabolism of zinc one way or another, with over a hundred requiring the direct involvement of zinc to induce catalysis. Zinc is of special note in a chemical reaction called hydroxylation, a process that helps cleanse the body of toxins. With hydroxylation, zinc participates in the conversion of lipid-soluble substrates into water-soluble products ready for excretion.

Modulates Immune Responses

The human body utilizes zinc in many different metabolic pathways that influence the processes needed for prompt immune responses. In the case of common infections such as colds and flu, zinc curtails severity of symptoms and raises immune responses to optimum levels. More importantly, healthy levels of zinc enable the body to take on preventative measures against diseases.

Remember even though zinc is an important mineral, to much can cause problems as well. Do not exceed 150mgs daily for extended periods of time to maintain safe levels of zinc. I suggest 15mg to 75mg daily.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2286)

Date: April 13, 2011 03:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Boswellia Fight Inflammation?

Boswellia refers to the species of trees where the aromatic gum resin frankincense is obtained from. In herbal medicine, the term Boswellia often means Indian frankincense, which is noted for its potent anti-inflammatory properties. It has a centuries-old association with Ayurvedic medicine, and herbal preparations containing its extracts are formulated for arthritis. It now comes in supplements marketed as a viable treatment for inflammation-induced illnesses, such as arthritis, colitis, and asthma.

Asthma

Indian frankincense, also known as dhoop in India, is entirely derived from Boswellia serrata, and the common frankincense from a completely different species. The earliest known study looking into its purported benefit as an anti-inflammatory medication was in 1998, and it investigated its effects on asthma. In a span of 6 weeks, the boswellia group took 300 mg of the preparation three times a day and 70 percent experienced a significant improvement in symptoms and a noticeable decrease in incidence of asthma attacks in comparison with the control group.

Arthritis

In Ayurvedic medicine, boswellia has been utilized for hundreds of years with an emphasis on its use in the amelioration of joint pains. It is generally considered safe, explaining its prevalence in the treatment of arthritis and related disorders. Boswellia was the subject of several studies devoted to better management of osteoarthritis, and these studies published results that attracted more research. Today it is also touted to be useful for rheumatoid arthritis, which is inflammatory in nature.

Colitis

Recent studies yielded outcomes in favor of its anti-inflammatory claims. In 2007 one study pointed to its medicinal potential in the treatment of colitis, concluding that patients with chronic inflammation of the colon went into remission after regular intake of boswellia. In a similar study, individuals diagnosed with inflammatory bowel disease reported to have benefited from 6 weeks of supplementation while those who sought conventional treatments responded to their medications in a much longer time.

5-lipoxygenase

Boswellia remains under scrutiny. Anecdotal evidence has been very positive largely owing to the fact that it hasn’t been linked to any adverse effect at all. But how does it work? There are many chemical reactions which boswellia may be directly involved in. It has been observed that it reduces the synthesis of pro-inflammatory leukotrienes. These mediators of inflammation are produced in the presence of an enzyme called 5-lipoxygenase, which is thought to be counteracted by the high terpene content of boswellia.

Leukocytes

Triterpenes in boswellic acid, the active ingredient unique to boswellia, are also believed to interfere with the adhesive interactions between leukocytes and endothelial cells present in the gastrointestinal tract. Leukocyte elastase is a serine protease, a special kind of enzyme, released by leukocytes or neutrophils during inflammation. It is postulated that boswellia down-regulates leukocytes and leukocyte elastase in addition to inhibiting the expression of endothelial cells adhesion molecules. Down-regulation of leukocytes will help reduce inflammation and improve health.

If you are fighting systemic or joint inflammation, give boswellia a try and feel the difference!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2272)

Date: April 02, 2011 12:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Butterbur Help Me with Migraines

Butterbur and Headaches

Butterbur has helped countless of migraine sufferers for more than three decades. In Europe, it is available as a prescription drug, which neurologists have prescribed since 1972. It has been the subject of numerous studies and reviews in a span of 40 years that have come to a conclusion that it does alleviate symptoms of migraine and reduce frequency of attacks. It is one of the herbal remedies clinically tested in migraine centers in the US. To date there has been no recorded adverse effects and harmful drug interactions, and as such available in the US over the counter, no prescription required. It has been compared to beta blockers and anticonvulsants and in general believed to be better than both of these more common treatments.

Petasites hybridus, the common butterbur, is the herb where butterbur extracts are obtained from although other species that belong to the genus Petasites are also known to produce the same health benefits. Petasites comprises up to 20 plant species widely distributed across the globe, a number of which have been tied to folk medicine throughout the ages. Petasites hybridus is native to North America and thrive well in marshes and wetlands, where there is a significant amount of moisture in the soil.

American Indians have long used its rhizomatous roots to fight off headaches and inflammation-induced diseases, such as asthma attacks and hay fever. Indeed the discovery of the organic compounds petasin, isopetasin, and oxopetasin explained its long-standing association with the treatment of migraines and allergies. Today most butterbur preparations do not contain pyrrolizidine alkaloids, which were identified to cause liver damage. That being said, it is still best to seek professional advice and ask assistance in choosing products from a reputable laboratory.

Interferes with Releases of Pain Chemicals

The phytochemicals unique to Butterbur have been well investigated, and results point to their effects on inhibiting the productions of local pain chemicals, which are pro-inflammatory in nature. Leukotrienes are lipid mediators that supervise the productions of other intermediaries of inflammation. Prostaglandins are responsible for vasodilation of blood vessels and their consequent sensitization to pain. Butterbur has been observed to influence these two pain chemicals.

Plays the Role of a Natural Beta Blocker

Beta-adrenergic antagonists, or simply beta blockers, are a class of drugs that target endogenous catecholamines implicated in migraine attacks. Epinephrine and norepinephrine are catecholamines that act on beta-andrenergic receptors, leading to a reduced blood flow in the brain. This results in the spasmodic contractions of cerebral blood vessels characteristic of migraines. Butterbur works on the principle of blocking the effects of catecholamines and inducing normal blood flow to the brain.

Produces No Known Serious Side Effects

Most analgesics and beta blockers have been associated with several adverse effects, which more often than not include nausea, dizziness, and muscle weakness. Many have been reported to cause weight gain. None of these have been linked to regular use of butterbur, one of the reasons why it has enjoyed a surge in popularity in recent years.

If you suffer from Migraine headaches, give butterbur a try!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2265)

Date: March 11, 2011 11:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why is It so Important to Give Your Child a Multiple Vitamin Mineral Supplement

Giving a multiple vitamin and mineral supplement to your child is tantamount to protecting him or her from the unknown dangers of malnutrition. It is a fact that children are picky eaters. Besides, not all food that you put on the table provides all the nutrients that they need. Experts remain divided over the need to give children daily multivitamins, but it is a common belief that doing so is just the prudent choice to make as parents. Does it make any difference? Yes, it does. Research has pointed to the positive effects of vitamin supplementation, and it has been cited a lot of times that the bioavailability of these supplements is not bad at all. This means supplementation does contribute to the well-being of your child.

Ensures to Meet Nutrient Needs

It is not a myth that our diet does not contain all the nutrients that we need. More often than not we are not getting the daily value for all vitamins and minerals as most of us are not able to monitor our eating habits. Also, we don’t have control over how sources of these nutrients change as they undergo the process of heating foods and other cooking preparations. With children being so picky, it is not surprising that they are susceptible to malnutrition. On the other hand, supplementation has been supported by decades-old research to meet the nutrient needs of individuals, including children. If you decide on giving your child multiple vitamin and mineral supplement, do check the label to make sure it says it contains 100 per cent of the recommended dietary intake of all nutrients.

Affects Growth and Development

A number of nutritional supplements available today have been proven to be of utmost help to the reversal of many medical signs and alleviation of diseases. Some of them have been associated with having a positive effect on the chemical reactions within the human body, and multiple vitamins and mineral supplements belong to this category. There is an ever-growing body of literature devoted to the interactions of exogenous compounds within the human body. Research on multivitamins in particular is among the most advanced in pharmacology, with emphasis on how the body effectively digests and absorbs them. Since the availability of vitamins and minerals is important to the physical and mental development of children, modern-day technology focuses on their absorption.

Strengthens Immune Defenses

There is scientific consensus that micronutrients, even trace minerals, boost our immune system. In fact, in individuals who have compromised immune responses, high quantities of vitamins and minerals slow down the progression of opportunistic diseases, as is the case with children with HIV. Children who have strong immune system are known to have levels of micronutrients adequate to ward off common illnesses. The opposite is also true. Multiple vitamin and mineral supplements have long been used to combat the dire effects of malnutrition as deficiencies are almost always reversed with supplementation. That being said, prevention is always better than cure.

Ensure you are getting the daily vitamins and minerals you need to maintain good health with a quality multiple vitamin and mineral.

What is stopping you from taking a multiple today?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2251)

Date: March 10, 2011 02:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does the Herb Holy Basil Help with My Health?

Holy Basil And Cholesterol, Inflammation, and more

Ocimum tenuiflorum, known as Holy Basil in the vernacular, is an herbal plant indigenous to South Asia, where it is called Tulsi. It is widely distributed across the subcontinent of India and surrounding countries and is primarily cultivated for its age-old medicinal benefits in addition to its religious significance to Vaishnavite practices of Hinduism. It has earned popularity as a health tonic over the centuries, and recent studies have supported its positive effects on human health. Today it is often associated with lowering cholesterol and glucose, acting as an antioxidant, and regulating inflammatory intermediaries.

Counteracts Stress Factors

The juice of holy basil has long been reputed to display adaptogenic properties. There have been countless accounts of its effectiveness in combating stress. In fact, the most compelling of all anecdotal evidence has something to do with its ability to create a feeling of wellness right after ingestion, the same tonic benefits attributed to ginseng. To date studies point to its homeostatic effects on the stress hormone cortisol, creating homeostatic effects on its metabolites and their interactions with compounds released in response to stress.

Neutralizes Free Radicals

Holy basil has been observed to show antioxidant activities, and this is one of its mechanisms in allaying symptoms brought on by fatigue. Free radicals are released by the body to dispose of pathogens, but are in turn disposed of by endogenous antioxidants. Oxidative stress ensues when there is an imbalance between the production of free radicals and the ability of the body to neutralize them. The polyphenols found in holy basil helps the body quench excesses of free radicals.

Lowers Bad Cholesterol

There has been a growing body of literature devoted to the lipid-lowering properties of holy basil. The phytochemicals found in holy basil have been cited to affect the metabolic pathway that produces very-low-density lipoproteins, which is a precursor to low-density lipoproteins, or bad cholesterol, and bring about an increase in high-density lipoproteins, dubbed good cholesterol. Also, it has been associated to the overall decrease of lipids present in the bloodstream, notably free fatty acids.

Reduces Blood Glucose

One of the earliest observations on the health effects of holy basil is its properties that counter the progression of diabetes. It has been reported many times to have helped patients of type 2 diabetes mellitus, which results from the compromised ability of cells to respond to the hormone insulin. The use of holy basil extracts has yielded promising results on promoting the glucose uptake of cells, and, of course, the consequent decrease in glucose present in the blood.

Influences Inflammation

Holy basil has been extensively studied for its anti-inflammatory benefits. The most recent research has pointed out that organic compounds found in holy basil may inhibit the enzyme called COX-2, which facilitates the synthesis of inflammatory mediators. Eicosanoids are endogenous substances produced by local tissues during inflammation, and a special group called prostanoids is responsible for the pain tied to inflammation. By targeting COX-2, holy basil greatly aids against inflammatory diseases such as arthritis.

What is stopping you from giving holy basil a try today?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2250)

Date: February 16, 2011 02:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Did You Know without Magnesium, You Could not Survive?

Magnesium and your Health

Magnesium is vital to life on all levels. All types of cells in all organisms must maintain a balance of magnesium to support life as we know it, and its presence in human beings is ubiquitous at a cellular level. Low levels of magnesium have been tied to a number of medical conditions such as asthma, diabetes, and osteoporosis whereas excesses are known to impair functions of tissues and organs, notably nerves cells and the kidneys.

Supplies the Human Body with Energy

Glucose is best known as the primary source of energy of most multicellular organisms, including of course human beings, while adenosine triphosphate, or ATP, is the form of energy yielded by the utilization of glucose within the cells. All forms of carbohydrates and fats from our diet must be broken down into simpler compounds to be able to be converted into ATP that powers cellular activities.

That being said, ATP requires magnesium in its participation in a number of physiological functions. What we refer to as ATP in fact contains ions of magnesium, for the former must be chemically bound to the latter to perform its role in interactions with protein kinases. In fact, it is a common observation that magnesium almost always acts as the functional regulator in the binding of proteins with ATP.

Participates in Enzymatic Reactions

More or less 300 hundred enzymes in the body are dependent on ATP, which we refer to as coenzyme, a kind of chemical compound that binds to protein. Magnesium acts as glue that keeps the enzymes and ATP together, aiding in the catalytic activities brought about by the enzymes and their utilization of ATP. Thus, the metabolic pathways that employ these enzymes rely on the presence of magnesium.

One example of the interaction of ATP with proteins that necessitate magnesium as a divalent cation, in other words functional regulator, is in enzymes that modify the molecular structure of other proteins. These enzymes are transcribed in more than 500 protein genes and affect up to 30 per cent of all proteins in the human body. Moreover, magnesium plays a role in ribosome, the cellular component responsible for creation of RNA copies and the manufacture of proteins.

Magnesium Facilitates Absorption of Calcium

Over 60 per cent of magnesium in the body is stored in the bones, and this fact has become the basis of the recent trend of dietary supplements that utilize magnesium to induce healthy bone density. Indeed low levels of magnesium has been reported to contribute to the degeneration of bones as we age, resulting in porous bone particles in a medical condition called osteoporosis.

Prevents Ailments of the Circulatory System

Since magnesium is essentially everywhere in the body, it significantly impacts the overall health of the circulatory system, notably in the prevention of heart diseases. Not surprisingly, insufficient levels of magnesium have been documented to cause cardiovascular problems, including hypertension and congestive heart failure, and supplementation of magnesium has been noted to cut complications of preexisting circulatory conditions.

Have you had your magnesium today?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2238)

Date: November 06, 2010 10:32 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bromelain Supplements why?

Bromelain enzyme may not be as familiar as other digestive supplements to most people but this helpful catalyst offers a wide range of benefits not only to the digestive system but also to other systems of the body.

Bromelain Enzyme Supplement

Bromelain enzyme is a proteolytic digestive catalyst that contains sulfur. From the word “proteolytic”, this substance aids in the digestion of proteins especially when taken with meals. On the other hand, when taken without meals, it is deemed to act as an anti-inflammatory supplement. Ananas comosus or the pineapple plant is the best source of this beneficial enzyme. However, fresh pineapple extract does not contain doses high enough to have a medicinal effect. Hence, a preparation to meet the body’s demand is produced. Bromelain supplements now come in the form of tablets and topical creams. They are now widely available and affordable to counterweigh the several uses it offers.

In the Digestive System, bromelain enzyme does not only help in digesting proteins but may also relieve gastric upset and heartburn especially when used together with other digestive enzymes like amylase, a catalyst responsbile for carbohydrate digestion, and lipase which is for the digestion of fats. Diarrhea conditions associated with deficiency in the proteolytic enzymes can also be alleviated with the use of this supplement.

In the Immune System, bromelain has been widely considered as an effective relief for pain and swelling caused by both injury and certain infections. Studies frequently show the bromelain’s ability in facilitating the body to restore health more quickly. The mechanism is said to be a reduction of fibrin and leukotriene accumulation, thus regulating the inflammation process. Researchers have demonstrated evidences that a daily intake of 1,200 to 1,800 mg of bromelain may help alleviate painful inflammation just like in rheumatoid arthritis.

In the Cardiovascular System, bromelain supplement is theorized to play a role in the prevention of heart disease caused by atherosclerosis or thickening of the arterial wall due to plaque deposits. It slows down the clumping of platelets thus preventing a possible heart attack.

Bromelain May Also Relieve Pain

Lastly, bromelain may also relieve pain associated premenstrual syndrome and menstraul cramps. Studies reveal that they act as prostaglandin inhibitors. However, bromelain can also increase the bleeding during menstruation.

Bromelain supplement has no Recommended Dietary Allowance but doses of up to 1 gram taken 3 times a day showed no toxic effects. Experts also advise to take bromelain on an empty stomach supplemented with magnesium to increase the bromelain’s effects.

Just like any other drug or food supplement, bromelain also has side effects, nonlife-threatening to be exact. It may have drug interactions such as increasing the absorption of some medications like antibiotics, chemotherapeutic drugs and specific antihypertensive agents. In addition, it may also bolster the effects of blood thinners such as warfarin (Coumadin), anti-inflammatory drugs and antiplatelet agents such as clopidogrel (Plavix). Since bromelain supplement can cause certain drug interactions, it is important to take this enzyme cautiously or under the supervision of a qualified health care provider.

To find quality bromelain supplements, look to your local or internet vitamin store.
~facebook~

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2193)

Date: November 05, 2009 01:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Clantro (Coriander Plant) to remove heavy metals

Cilantro Heavy Metal Detox With Chlorella

Planetary Herbals is pleased to introduce Cilantro heavy metal detox, a unique herbal cleansing formula for defense against today’s environmental toxins. The herbs in Cilantro heavy metal detox are known to bind to heavy metals, helping to clear them from the body. Chlorella is added to increase the chelating and cleansing actions of cilantro. This combination also provides effective antioxidant support for overall cell health.

Planetary Herbals Cilantro heavy metal detox contains organic cilantro leaf and organic chlorella, for the purest product possible.

Herbs: Nature’s Answer to a Toxic World

Cilantro (one of the names used for the leaves of the coriander plant, Coriandrum sativum) is an ancient herb that has been used for millennia for health and for its robust, savory taste. Beyond its culinary value, modern research has confirmed the benefits of cilantro as a natural means of internal cleansing.

Recent studies show the cilantro attaches to heavy metals in the bloodstream. This process, known as “Chelation,” helps our bodies eliminate metals from our systems, and helps cleanse and purify our tissues, organs and blood. This process is supported with the addition of chlorella, single celled algae that work synergistically to enhance cilantro’s chelating and cleansing ability.

Binding heavy metals

Thousands of noxious chemical compounds, many of which didn’t exist on the planet 100 years ago, now pervade our food, water, and air. Heavy metals like lead, mercury, arsenic, aluminum, and cadmium enter our bodies through food, air, cooking utensils, deodorant, and even the fillings in our teeth.

Cilantro’s properties that enable binding with these toxins are thought to come from unique constituents, including citric acid, phytic acid, and electrolytes that attach to metals. The sequestration of metal ions by chlorella is assumed to be accomplished by surface ligands in the cell walls. Simply stated, both cilantro and chlorella contain properties that bind with metals, and chlorella additionally helps purge the bound metals from the organs.

Planetary Herbals: the PhytoDynamic Difference

Cilantro heavy metal detox is the latest in a herbal product line based on the principles of PhytoDynamics. PhytoDynamics unites a profound understanding of the interaction between plants and people, a commitment to holistic integrity of herbs for optimal efficacy, a strong grounding in scientific research, a world class quality control team, and a level of clinical expertise unmatched in the industry.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2110)

Date: July 31, 2009 12:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Sarsparilla

Sarsaparilla can be found natively growing in the Pacific regions of Mexico, along the coast to Peru. The root is commonly used to make root beer. The sarsaparilla plant is mostly a find. It can primarily be found in Mexico, Central America and South America. The root of the plant is the most valued portion. It has been used for medicinal purposes for centuries, much like ginseng or licorice root. Sarsaparilla root is very bitter. Because of this, it was a common practice for pharmacists to distill the useful chemicals from this herb and mix them with sugar water. From this, a very popular beverage called sarsaparilla was born. This was years before other chemists would invent other medicinal drinks like the original Pepsi and 7-Up.

The sarsaparilla plant was most definitely used as a medicinal tonic, but it was often served as a sweetened beverage. Some formulas substituted sarsaparilla root with a combination of birch oil and sassafras, which is a treat that is found in the western United States. Some believe that the informal name of the drink, sasparilla, indicates the use of sassafras extract, while others say the name is a corruption of the original sarsaparilla. Unfortunately, the modern beverage is closer to a birch oil/sassafras mixture than the more bitter sarsaparilla extract. The roots of the sarsaparilla plant can be purchased in certain grocery or health food stores. The beverage called sarsaparilla is a little more difficult to find. Smaller bottling companies may produce a version for local consumption, but that national interest in root beer, sarsaparilla’s cousin, has made it much harder to come by.

Often, sarsaparilla is used in glandular balance formulas. This is because components in sarsaparilla help with the production of testosterone and progesterone. The herb also stimulates the metabolism, aids digestion, and improves the appetite. It has been used to help with gas and edema, along with other related conditions. Additionally, studies have shown that this herb contains diuretic activity and also increased the elimination of chlorides and uric acid. Sarsaparilla is beneficial for many skin ailments. Among these are psoriasis, eczema, and leprosy. This has been found to be true in various studies. The herb also works as an anti-inflammatory by increasing circulation to rheumatic joints. It also helps to relieve arthritis and other inflammatory conditions. This herb also stimulates breathing when congestion occurs. It even helps to purify the blood.

The root of the sarsaparilla plant are used to provide alterative, anti-inflammatory, antiseptic, aromatic, blood purifier, carminative, diaphoretic, diuretic, febrifuge, and stimulant properties. The primary nutrients found in this herb are copper, iodine, iron, manganese, silicon, sodium, vitamins A, B-complex, and C, and zinc. Primarily, sarsaparilla is extremely beneficial in treating joint aches and pains, arthritis, blood impurities, eczema, gas, glandular problems, hormone imbalance, inflammation, psoriasis, skin diseases, and syphilis.

Additionally, the herb is very helpful in dealing with age spots, appetite loss, cods, congestion, edema, sore eyes, fevers, gout, impotence, leprosy, menopausal symptoms, metabolism disorders, skin parasites, chronic rheumatism, ringworms, primary tuberculosis, and sores. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen to prevent prescription drug interaction. For more information on the many beneficial effects provided by sarsaparilla, please feel free to consult a representative from your local health food store with questions.

Sarsaparilla root is available in capsule and tablet forms at your local or internet health food store. It is recommended that you look for name brands like Solaray, Natures Way, and Natures Plus to ensure quality and purity of the product you purchase.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2039)

Date: June 18, 2009 10:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Colostrum

After going through puberty, our bodies gradually decrease in the production of immune and growth factors that generally combat disease. After losing these vital components, we are much more susceptible to the aging process, which shortens our life expectancy. Colostrum and its other components have the ability to fight off bacterial and viral invaders as well as stimulate tissue repair, which is something that becomes increasingly vulnerable as we age by boosting the immune system. For all of these reasons, it is important for an adult to supplement with colostrum.

Colostrum should be collected during the first 24 hours after birth. Also, a colostrum supplement should be processed in a USDA licensed facility. This insures the consumer that USDA guidelines are being followed. Additionally, consumers should make sure that products labeled Colostrum are actually 100% colostrum, not colostrum or concentrates of milk whey. Lastly, colostrum that is mixed with other supplements or herbs and additives may have a diluted colostrum concentration, which means the benefits you could obtain from this supplement may be compromised.

Even though colostrum has no interactions with drugs, side effects may be experienced from a cleansing or healing crisis, which is a necessary but somewhat inconvenient and adverse result. Fortunately, once the healing crisis is complete, you will feel substantially better and in good terms of health. Mediations may need to be re-evaluated by your medical profession for dose and need.

Although colostrum is generally believed to be very safe for those mothers who are pregnant and nursing, one should probably ask their medical professional prior to taking colostrum or its specific agents while they are pregnant. Just like any other supplement or drug, it is better to be overly safe and check with a healthcare provider before jeopardizing a pregnancy.

Colostrum is recommended specifically for children who have not already received the mother’s breast milk, as breast milk would have already provided the benefits that would be obtained through colostrum supplementation. Those children with flu, colds, bacterial or viral infections, or children who have been on long or short-term antibiotics or other drugs are good candidates for colostrum supplementation. Therefore, colostrum supplementation is safe and may be recommended for these types of children.

Many people wonder if colostrum products can pass on mad cow disease. At this time, no case of mad cow disease has been reported in the United States. With awareness of the disease being so high, it is extremely unlikely that one would contract mad cow disease from a colostrum product.

The overall supplementation of colostrum and other products that contain derivatives of colostrum has been shown to extremely safe. Additionally, it has been shown that colostrum is equally effective, whether it be taken by injection or by mouth. It has also been shown that the long-term administration of colostrum preparation is very safe to the human body. Because infants and the elderly are the two main groups that are especially at risk for infections, many people may wonder just how safe colostrum products are for these two groups of people. Not only is oral administration safe, it is also very effective and easily accepted by both of these groups.

Colostrum is available in capsule of tablet forms at your local or internet health food store. Look for name brands like Kal and Source Naturals to ensure quality and purity of the product you purchase.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Colostrum is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2020)

Date: June 11, 2009 06:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boswellia Extract

The boswellia family of trees are specifically known for their fragrant, gummy sap, which possesses many medicinal uses. Among these, especially, if the use as an anti-inflammatory. It is believed that the frankincense of the bible was actually an extract from the resin of the Boswellia tree. Boswellia, which is also known as boswellin, has a long history of use in Ayurvedic healing. The resin is called salai guggal and has been used to treat asthma, arthritis, various inflammatory conditions, and to relieve joint pain and pain that results from sports injuries. The resin of the boswellia tree is also though to be helpful for treating back pain as well as some other chronic intestinal disorders.

The boswellia plant is a genus of trees that are known mainly for their fragrant resin. This resin has many pharmacological uses, particularly as anti-inflammatories. There are four main species of boswellia, producing true frankincense. Each type of resin is available in various grades. These grades depend upon the time of harvesting. The resin of the boswellia plant is hand sorted for quality. Anyone who is interested in frankincense is advised to obtain a small sample from each reputable dealer to determine the difference between each resin.

Boswellic acids are the main compounds that are believed to be at the source of boswellia’s anti-inflammatory properties. These acids have the ability to inhibit the enzymes that induce pain and inflammation in the body.

A few studies have been conducted on boswellia’s effect on sports injuries and arthritis. Among these, some have shown that boswellic acids may contain anti-inflammatory benefits that are extremely powerful. These benefits are similar to those found in ibuprofen and aspirin. One study done on rheumatoid arthritis patients found that pain and swelling were reduced after three months of treatment with boswellia. Those who used boswellia occasionally reported mild gastrointestinal distress, like heartburn and nausea, but there were no other reports of serious side-effects.

Boswellia has a long tradition of safe and effective use as a mild anti-inflammatory to alleviate pain and stiffness. It is also used to enhance mobility without serious side effects. However, further research is needed to confirm the long-term safety and effectiveness of this extract. Boswellia seems to be best taken as needed in order to reduce pain and stiffness, as opposed to being taken regularly as a maintenance herb.

The resin of boswellia is used in many herbal formulas because of its analgesic and anti-inflammatory properties. Primarily, this extract is most useful in dealing with arthritis, asthma, inflammatory conditions, joint pain, and sports injuries.

A boswellia standardized extract is recommended by many doctors. When dealing with rheumatoid arthritis or osteoarthritis, 150 mg of boswellic acids are taken three times per day. For example, if an extract contains 37.5% boswellic acids, 400 mg of the extract would be taken three times daily. Treatment with boswellia should generally last between eight and twelve weeks. Generally, boswellia is safe when used as directed. Rare side effects include diarrhea, skin rash, and nausea. Any inflammatory joint condition should be closely monitored by a health care professional. To date, there are no well-known drug interactions with boswellia.

Boswellia comes in capsule form at your local or internet health food store. When making a purchase always read the label to ensure that the product is standardized to its active acids to ensure quality and purity and to ensure that the herb when taken regularly will function as intended.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Boswellia is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2017)

Date: January 29, 2009 03:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hoodia

Some companies are already manufacturing a blend of cheaper ingredients with hoodia, and claiming it is better than hoodia alone. This means that you might find a product that contains 1,000 mg of total ingredients, but it could contain as little as 50 mg of hoodia. As a general rule, the other ingredients are only included to make the product cheaper. All hoodia supplies are the same strength worldwide. The stems of the plant are picked, dried, and milled, leaving a powder about 5 percent of the original weight, which is why some quote it as a 20:1 extract. However, don’t be misled. Despite what a label may lead you to believe, you’re only getting 50 mg of hoodia.

The minimum dosage that is necessary to have a usable effect is about 800 to 1,200 mg of actual hoodia each day. This amount will help to reduce your appetite so that you can eat smaller meals and, consequently, lose weight. If you think you’d like to try hoodia, look for a product that has been naturally extracted and grown or ethically wild crafted without the use of chemical fertilizers, pesticides, or preservatives, preferably in a vegetarian capsule.

Make sure that the product you use is a true standardized full-spectrum herbal supplement that does not include any fillers, binders, or common allergens. Also, keep in mind that even though safety reports to date are encouraging, no long-term safety studies have been performed. Additionally, there is no data on the possible interactions hoodia may have with other drugs.

Hoodia is a non-stimulating herb, which makes it more suitable for a large range of people. Herbal stimulants such as guarana or kola nut, which both contain caffeine, can cause a large range of side effects such elevated heart rate and blood pressure, nervousness, and sleeplessness. P57, the active ingredient in hoodia, has no sedative effects.

Losing weight and maintaining an ideal weight also requires changing attitude and lifestyle. If your main goal is to quickly lose weight so you can fit into your bathing suit, you may be able to achieve that lighter weight, but without exercise, you’re still going to look flabby. Even though the subjects in the hoodia clinical study did not exercise, you should, as exercise plays an important role in losing and managing weight along with overall health.

Weight loss should be about your overall health. Without the proper eating habits, especially nutrition and exercise, you won’t be able to accomplish much. It’s true that less weight puts less stress on your cardiovascular system, but you need to exercise to strengthen your heart muscles. Proper nutrition and exercise also helps to prevent many other health problems, which includes fighting off many digestive ailments.

If you’re considering trying hoodia for weight loss, experts suggest that you supplement with 800 to 1,200 mg a day, divided into two doses and taken with water. For best results, follow the manufacturer’s dosage instructions since products may vary. You should also follow a reduced-calorie diet of natural, unprocessed foods. Even though you can probably lose weight on a diet like this without supplementing with hoodia, adding hoodia may help you to stick to your diet better.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1962)

Date: October 01, 2008 12:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Control Blood Sugar Naturally

Diabetes is an inflammatory condition caused by the autoimmune system, and manifests as resting hyperglycemia. Your blood glucose levels have to be maintained within fine concentration limits: both too high and too low a blood glucose concentration can be dangerous to your well being.

Your blood glucose level is generally controlled by insulin and glucagons, both of which are biosynthesized in the pancreas. Insulin works by making the glucose bioavailable to the mitochondria to convert into energy, while glucagon, the lesser known of this twosome, stabilizes the level of insulin and mobilizes it to do its job. There are two types of diabetes, known as Type I and Type II or A and B.

Type I diabetes, also known as juvenile onset diabetes, is an autoimmune condition in which the immune system destroys Beta cells because they are recognized as being foreign. It is the Beta cells that generate insulin, and so the condition can be fatal. Patients with Type I diabetes must take insulin throughout their lives, and while potential cures are currently under investigation, none are yet available. Although insulin can be effective it does not guarantee survival, and a better form of treatment is required.

Type II diabetes is by far the more common of the two, and is a form of resistance to insulin, where the body cells cannot use insulin properly. The pancreas initially reacts to this by producing more insulin in response to the increased blood glucose level, but through time it loses its ability to produce insulin as a reaction to an increase in blood sugar, even though this occurs as a result of digesting a meal.

The exact causes of either type of diabetes are not known for sure, although the general mechanism by which they work is known. However, Type II diabetes is believed to be due to some form of interaction between genetics and environment, and it is known that the majority of Type II sufferers are obese and also over 40.

The treatment for this type of diabetes is rarely insulin, but a controlled diet, control of your cholesterol level and blood pressure, exercise and specific medicines designed for sufferers of this form of diabetes. However, there are also natural supplements that can be used to control your blood sugar levels. Diabetes was the sixth leading cause of death of the USA in 1999, with 450,000 deaths, and by 2005 had reached about 300 million sufferers world wide. It is therefore a serious and widespread condition, though Type II is less serious than Type I.

It is important to do what you can to control your diabetes, since after several years it can lead to problems with your nerves, eyes, kidneys and gums, and can also lead to heart disease. With diabetes you are at least twice as likely to have a stroke or heart problem as those without it, although you can reduce the risk of this by keeping your blood pressure under control, and the levels of fats in your blood to a minimum. Stopping smoking helps, and there are some natural treatments that can also help you control your diabetes.

The most important means of control is to reduce your blood sugar levels. While there are natural products that will help you to do that, do not stop taking the medication prescribed by your doctor, but use these in addition to what you are already taking. Among specific substances that can help are:

Chromium: chromium helps your body to use insulin properly. When taken in the form of chromium picolinate, it helps to replace chromium that diabetics appear to be short of. Human studies have indicated that chromium can decrease insulin levels and improve the metabolism of blood sugar in those with Type II diabetes. Some claim that chromium is harmful to health, but the general opinion is that it helps, though you should consult your doctor before using it.

Cinnamon: If you take cinnamon daily, your blood sugar levels should gradually decrease. It appears to enable your cells to make better use of the insulin your blood, although there still discussion as to the mechanism by which this occurs and of the active ingredient in cinnamon that promotes it. Some claim it to be a flavonoid known as methylhydroxychalcone polymer, or MHCP. However, others claim it not to be MHCP, but polyphenol type-A polymer. Whichever it is, many people are finding cinnamon to be effective in reducing high levels of blood sugar to a more manageable level.

Milk Thistle: It is known that antioxidants can help to control blood sugar, and the flavolignins in Silymarin marianum, an herbal extract available from milk thistle seeds, work in this manner. It is also good for protecting the liver from toxins. Although it is not clear how it is done, silymarin appears to help to control Type II diabetes possibly by way of liver digestion of sugars in the blood. The liver processed glucose and improving its function through the consumption of milk thistle could help reduce blood sugar as well. Mulberry: The Chinese make what is known as “sugar control herbal tea” from mulberry leaves, green tea and jasmine. Mulberry leaves contain adenine, pectin and choline, and also high levels of Vitamins A and B types. This tea is used by the Chinese to control blood sugar levels, which might occur through the antioxidant effect of the mulberry constituents.

Salacia oblonga: This is an herb used in India and Sri Lanka that appears to cause a dramatic drop in the levels of insulin and sugar in the blood. It binds to enzymes in the intestine that break carbohydrates down into sugars, and so reduces the amount of sugar in your blood. That in turn reduces the amount of insulin released by the pancreas.

Apple Cider Vinegar: There is evidence that apple cider vinegar can help to control your blood sugar levels if taken before a meal. Just two tablespoons appears sufficient to give a noticeable result. This is one of those home remedies that might be just anecdotal, but might also work, so is worth trying.

Zinc: It has been discovered that diabetics suffer a deficiency in zinc. This mineral plays a part in the storage and production of insulin in your body, and a deficiency could cause an increase in your sugar level. Oysters, pecans, almonds, lamb and chicken are all good sources of zinc.

Glyconutrient complexes: we know that diabetes is an autoimmune disease for type I individuals. Supporting a properly function immune system requires a good diet as well as a diet rich in Glyconutrients. The polysaccharides found in glyconutrient formulas can help the immune system communicate better with the body and just possibly correct some autoimmune diseases which attach our cells.

These are the natural supplements that people are taking to help control their blood sugar and diabetes. It is important that you take nothing that interferes with the medicines given to you by your physician, so you should let your doctor know of any natural supplement that you are using in addition to your prescription medicines. However, it is possible to control your blood sugar with natural supplements, and those mentioned above are just a few of the natural substances available that can help diabetics control their condition and so avoid the side effects.

--
Buy Blood Sugar Vitamins at Vitanet ®,LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1906)

Date: July 08, 2008 03:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garcinia Cambogia

Garcinia cambogia is a small tree bearing a small pumpkin-like fruit of the citrus family, and is steadily appearing in an increasing number of weight loss supplements. It is indigenous to parts of Africa and Asia, and the rind is commonly used in Indian cookery.

Although the fruit is particularly sour to the taste, it is used in form of an extract of the rind and claimed to act as an appetite suppressant and also to increase the body’s capacity to metabolize fat. Although there are conflicting claims being made about its efficacy, or lack of it, research shows that it definitely has promise as an agent to prevent and fight obesity and its use is steadily increasing in this respect.

The active ingredient is hydroxy citric acid, otherwise known as HCA, contained in the form of the potassium and calcium salts of the acid in the aqueous extract of the garcinia cambogia rind. It forms up to 30% by weight of the rind. It is tasteless and odorless, and so far found to have no toxic effects on humans. Animal studies have also been generally favorable.

HCA works in two specific ways both to reduce the desire to eat and to inhibit the storage of fat in the body. In each case, as with so many supplements that have an inhibitory effect on a physiological or psychological function or on a metabolic process, it involves an interaction with enzymes.

Citrate lysase is an enzyme in the body that helps to prevent lipogenesis and instead promotes the conversion of carbohydrates into fat. When this enzyme is inhibited from carrying out its intended part in the body’s metabolism, the process of carbohydrate oxidation is boosted, or, in other words, the excess carbohydrate is burned off, or changed into energy.

More fats could also be expelled unchanged from the body, but irrespective of that the end result is that less carbohydrate tends to be converted to fat. Garcinia cambogia, however, has not been found to reduce the body’s uptake of essential fatty acids which are necessary for health. Had this occurred, you would feel a raging hunger as opposed to the appetite suppressing properties the extract is claimed to have.

The oxidation of carbohydrates can also lead to thermogenesis, or the boosting of the metabolism by increasing your body temperature. An increase in the metabolic rate helps weight reduction through an increased calorie demand while your body is at rest. However, that is not the only way in which the HCA extract works to help reduce your weight, or at least help to maintain it at a healthy level. Let’s return to its specific appetite suppression properties.

Serotonin (5-hydroxytryptamine) is a neuroreceptor found in the central nervous system. It has many regulatory effects on the body, one of which is appetite. Although it is by no means the only chemical in the body that has an effect on the appetite, serotonin is a significant factor. As you get hungry, serotonin is released in the hypothalamus, an area of the brain that regulates sleep and eating. The release of serotonin increases when you see and or smell food. It is the agent that starts canine salivation, and a ravenous hunger in those that have no immediate access to food.

It also causes you to snack, and, as you eat, the serotonin level in the hypothalamus continues to increase until it reaches a point where it provides the hypothalamus with a feeling of repletion or satisfaction. You then stop eating. So the more serotonin is produced, the quicker you stop feeling hungry.

Garcinia cambogia extract has the effect of stimulating the emission of serotonin into the hypothalamus, and so suppresses your hunger quicker. You don’t stop eating altogether, but attain that feeling of satisfaction much quicker and so tend to eat less with each meal. This can not only help you maintain your weight at a healthy level, but also to reduce weight in the obese.

Although the extract can work through each of these mechanisms, it does not have such a significant effect on a very fatty diet. It can help if you switch to a relatively healthy diet, lower in fats, but the effect might not be strong enough to compensate for a poor diet in terms of fat content.

Studies have indicated an anti-oxidant activity that likely comes from the xanthones and xanthone derivatives that are also contained in the fruit. In fact there are other recorded uses of garcinia cambogia, and it has been used in traditional Indian medicine to treat fevers, dysentery, open wounds, ulcers and tumors.

According to a study carried out for the National Cancer Institute there is no documented toxicity effects on humans, and there is no regulation regarding the use of garcinia cambogia. It has not been evaluated by the FDA.

However, there are contra-indications in the case of pregnant and lactating women, more as a safety measure than for any particularly known risk. Alzheimer patients should avoid taking HCA since there is a possibility of it promoting the synthesis of acetylcholine in the brain, and its glycemic action renders it unsuitable for diabetics.

Conversely, this same action is a positive benefit by reducing the craving of healthy adults for sweet foods. However, HCA is frequently taken in combination with chromium due to the latter’s positive effect on the regulation of blood sugar levels. Nevertheless, diabetics should avoid any supplement containing chromium without professional medical advice.

The supplement should be standardized on the HCA content, and an average dose is around 500 mg – 1000 mg of 50% extract a day. However, this varies, and the most important aspect of such extracts is that when changing brands; be sure to compare the strength of the relative extracts and change your dosage accordingly.

Although the benefits of garcinia cambogia to those seeking to lose weight are debated, there is ample evidence to suggest that a regular intake of the extract is beneficial – and not only with respect to the maintenance of healthy weight.

--
Buy Garcinia Cambogia at Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1833)

Date: June 23, 2008 03:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: B Vitamin Complex

The vitamin B supplement you take is a mixture of nutrients that, although they share the same vitamin letter, are in fact distinctly different chemical entities. The reason that they share the same reference letter of the alphabet is that they are all essential water soluble vitamins (Vitamin C being the only other), they frequently work in synergy with each other and they often come from common sources and have similar properties in the body. They were therefore at one time believed to be just the one chemical entity.

They are essential in that they must form part of our diet because our bodies cannot manufacture these substances from others, and although most share common biochemical and health functions, there is no health function that requires all of them, and none of them can be totally replaced by another.

The B-Vitamin complex that you take can consist of as many as eight different B vitamins, each of which is essential for a healthy body and at one time it was believed that this mixture was only one single vitamin. That is why they are collectively known as vitamin B and were subsequently allocated numbers: it was only later that the individual components were discovered.

These eight are vitamin B-1 (thiamine), vitamin B-2 (riboflavin), vitamin B-3 (niacin), vitamin B-5 (pantothenic acid), vitamin B-6 (pyridoxine), vitamin B-12 (cobalamins), biotin and folic acid (folate). They are found in yeast, liver, tuna, bananas and rice among other sources, and, as with all vitamins, without them life would not be possible. Not all vitamins are found in each of these food sources, and vitamin B-12, for example, is available in nutritional quantities only from animal sources.

Knowing what they are is all very well, but what does your body do with the B vitamin supplement that you take? Before considering that, the reason that a regular supply is important is because of their water solubility. This is a useful property for a vitamin to possess, because it means that they can easily be transported by the body fluids to the tissues where they are needed. The downside, however, is that they are consequently also easily flushed from the body, and your body cannot store any of the B vitamins.

You therefore must have a regular dietary source that can be augmented through supplementation. This is particularly desirable in alcoholics, those on diets to lose weight and vegans who are advised to take a regular vitamin B-12 supplement.

A lack of vitamin B will make you feel tired and lack energy because they play a big part in your body’s metabolism of blood glucose into energy. They also help to maintain a healthy immune system, keep your nervous system in tip-top condition and maintain good healthy skin, hair and muscles. The B complex is also very important in maintaining healthy blood and liver, and each and every component of the mixture has a specific part to play, both on individually and by interaction with others in the B complex.

Rather than examining what your body does with the supplement as a whole, let’s have a look at each component, and what your body does with that. Taking them one at a time, thiamine (B1) helps you to burn carbohydrates to generate energy. It is highly water soluble and must be taken daily. In the form of thiamine pyrophosphate it plays a key part in the metabolism of carbohydrates to energy, and also in the metabolism of certain amino acids. If you rely heavily on a high carbohydrate diet, you will need a good regular supplement of thiamine to be able to convert them to energy.

Vitamin B2 (riboflavin) also plays a part in fat and carbohydrate metabolism and the formation of adenosine triphosphate (ATP), the molecule of energy. It plays a significant part in the health of your skin and a deficiency is associated with mouth ulcers, cracked lips, flaky skin and bloodshot watery eyes. It also activates vitamin B6 and folic acid, one of the cases where the B vitamins work together synergistically.

Vitamin B3, or niacin, is well known to women as a component of some shampoos, and helps to promote health hair. However, this vitamin also takes part in the process of energy creation within your body, and helps to maintain a good muscle tone within the digestive tract. It is also used as a supplement for the treatment of diseases related to high levels of LDL cholesterol and is useful for the treatment of atherosclerosis.

Pantothenic acid is also found as a component of shampoos, so no prizes for guessing one of its functions. Vitamin B-5 plays a significant part in the energy-producing Krebs Cycle, or Citric Acid Cycle, that is used by every cell in your body to generate energy just where it is needed. It is also needed to synthesize acetylcholine, a neurotransmitter needed for good brain function and it helps to reduce stress. Pantothenic acid is also closely involved in the production of cholesterol in your liver: cholesterol is not all bad, and is needed by your body to produce some of the steroid hormones and also vitamin D.

Amino acids are the small units that are used to biosynthesize proteins and ultimately the genes and DNA that determine who you are. The major factor involved in processing these amino acids is Vitamin B6 (pyridoxine), one of the lesser known of the vitamin B complex. It synthesizes and breaks up different amino acids to produce a variety of other compounds, such as the hormones serotonin, melatonin and dopamine.

Deficiencies in these hormones can be very serious, Parkinson’s disease believed to be connected with a dopamine deficiency for example, and other disorders include kidney stones, anemia and many skin complaints. Although deficiency of vitamin B6 is rare, it can occur in alcoholics and those with chronic kidney problems. It is believed that many diets are deficient, however, and a good vitamin B supplement would ensure that this did not occur.

Vitamin B-12 is one where deficiency can occur, particularly in alcoholics and vegans. It is available in sufficient quantities only from meat sources, and a supplement is indicated in anyone with a low meat intake in their diet. It is used by your body for the replication of DNA and to allow the normal activity of your body cells. It also helps to control homocysteine levels in conjunction with vitamin B6 and folic acid: homocysteine is a high-risk amino acid associated with atherosclerosis and cardiovascular disease that can lead to Alzheimer’s disease, heart attacks and strokes.

The seventh, biotin (sometimes referred to as vitamin B7) also takes part in the metabolism of energy, but deficiencies have not been known, and the final known member of the B vitamin complex is folic acid. This is essential for cell growth and the synthesis of RNA and DNA in the body. RNA (Ribonucleic acid) is responsible for the synthesis of proteins in your body, and the well known Deoxy-ribonucleic acid (DNA) holds the genetic information of your body. Folic acid is therefore essential in the growing fetus, and any other cellular system that rapidly regenerates such as blood cells and the various cells of the immune system.

Without folic acid your body would be more susceptible to bacterial and viral attack, and less able to protect you from foreign invaders into your body tissues. Although deficiency is not common, folic acid is present in fresh food only and degrades when stored at room temperature and when cooked. A supplement is therefore advisable during pregnancy to help to prevent neural tube defects.

It is evident that the Vitamin B complex plays many parts in the chemistry of your body, and that a supplement can be of benefit in assuring that there are no deficiencies. A good B complex can be found at your local or internet health food store.

--
Buy a B-Complex at Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1825)

Date: June 17, 2008 10:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Chromium Picolinate

Chromium picolinate, broken down, is chromium that is bonded to an amino acid. The chromium portion of the compound is not well absorbed by the body. Therefore, the amino acid picolinate is added to aid in absorption.

Studies have shown that 90 percent of the adult population in the United States has a chromium deficiency in their diet. The best source of chromium is true brewer’s yeast, but it is found in grains and cereals in smaller amounts. Refined forms of these foods are likely to be lacking in sufficient chromium levels. Strenuous physical activity requires a larger intake of chromium in the diet.

Chromium picolinate, a chromium supplement, has profound effects on the body’s overall nutrition and health. It has increased in popularity in recent years because it helps to reduce body fat and increase lean body mass. Research has proven that it can aid in treating:

* High blood sugar
* High blood fat
* Obesity
* Food cravings
* Osteoporosis
* Lack of energy
* Trouble controlling weight
* Low metabolism

In the late 1950s, chromium picolinate was discovered to be essential for proper blood sugar control. It is a key part of desensitizing the body to insulin. Without chromium, blood sugar levels are elevated because insulin is blocked from doing its job. Chromium is one of the essential trace minerals. Its most important function is to work with insulin, which is a hormone. Insulin is responsible for the body’s ability to break down carbohydrates, proteins and fats naturally. Your metabolism affects every cell in your body. All bodily functions are dependent on the proper use and breakdown of these chemicals.

A deficiency of chromium in your diet will lead to an impairment of insulin activity. This insulin resistance allows more glucose to remain in your body, resulting in weight gain and loss of energy.

Insulin is the most important hormone involved in metabolism. Everyone’s body requires proper insulin function to be healthy. Insulin is secreted whenever you eat. It then binds to cells to activate sugar absorption from your bloodstream. The body’s sugar (glucose) is its strongest energy source. The cells use it to fuel the body’s essential functions like metabolism and building muscles.

Because of these needs, chromium picolinate can be used as a supplement to promote weight loss and treat high cholesterol and diabetes. It is an essential supplement for healthy metabolism, especially in older people. People who lack enough chromium picolinate in their diets usually have trouble keeping weight off and feel run down regularly.

Chromium Picolinate and Weight Loss:

Chromium picolinate is not a viable quick fix for permanent weight loss. It is, however, a valuable addition to a healthy and well-designed weight loss program. People who are overweight are generally insulin resistant. For this reason, additional chromium supplementation aids in healthier metabolism and more productive use of insulin. The result is increased weight loss when used in conjunction with proper exercise and a well-balanced diet.

Dietary Interactions and Safety:

Chromium picolinate has been shown in studies to be safe for use with most medications. However, as with any dietary supplement, it is important to discuss your use of this supplement with your physician before planning any dietary changes.

Chromium picolinate was safe in studies in which it was used in amounts exceeding 500 times the recommended daily dosage. The production of this dietary supplement is under the highest quality and safety conditions available. No side effects have been reported since chromium picolinate has been available on the market.

Most daily multiple vitamins contain the recommended daily allowance of chromium picolinate. However, since it is so difficult for the body to absorb effectively, most people need more supplementation than is generally recommended.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1818)

Date: May 16, 2008 02:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coral Calcium

The health benefits of coral calcium were discovered in 1979, when a British journalist representing the Guinness Book of records traveled to Okinawa to talk to Shigechiyo Izumi, who at 115 years old was at the time the world’s oldest documented living human being. Not only was the journalist impressed and surprised at how healthy such an old man was, but he also found that good health to be shared by the majority of Okinawa’s aged residents.

After his report was filed on his return to England, a team of researchers were sent to the island to make further investigations in the phenomenon. They found that the key to their longevity was the water they were drinking. The water of Okinawa appeared unique, and coral calcium was discovered.

It was not only the calcium, of course, that made such as difference but the whole mineral balance of the water. Okinawa is formed of coral reefs built up over millennia, and rainwater filters down through the coral collecting minerals and other nutrients on its way. This water is both alkaline, with a pH of 8.6, and closely resembles the natural mineral composition, not only of the human skeleton but also of body fluids such as blood plasma and amniotic fluid. It seemed the ideal stuff to bottle, and there are now over 4 million users of coral calcium in Japan alone.

The commercial use of Sango coral, as it is called, is controlled by the Japanese government, and living coral is left untouched: only the dead coral sand lying on the ocean bed is used. The sand is collected and cleaned, and then pulverized and the calcium and all the rest of the minerals it contains are easily absorbed by the body.

It is this ease of absorption that renders coral calcium so useful. Most minerals find it difficult to pass from the intestine to the bloodstream, but this is not a problem for the minerals in Sango coral. Because they do not come from inorganic mined minerals, but from natural organic sources, they are present in a very bio-available form and are readily absorbed into the bloodstream. It not only contains the common minerals calcium, magnesium, potassium, sodium, and so on, but also many trace elements that are essential for life. Not only that, however, but they also contain antioxidants to help prevent the oxidative stress caused by free radicals, and also at a pH that allows the minerals to become naturally ionic very readily.

It is this ionic form of each mineral that permits it to be so readily available to your system. This was a major discovery at the time, since the form that inorganic minerals generally come in had been a problem prior to this to the extent that only 10% was absorbed by the body. In comparison, 95% of the coral calcium and other minerals are able to be easily absorbed since they are in an ionized form – an even higher absorbency than colloidal minerals allow.

Why are minerals so important and how can they possible lead to such an effect on the elderly of Okinawa? In fact minerals are very important components of human metabolism and biochemistry. Most believe vitamins to be significantly more important to human health than minerals, but this is not the case. Many vitamins are useless without the synergistic effect of minerals, and the reverse is also the same.

For example, calcium needs vitamin D to be present before it can be used by the body to strengthen bone structure. There are many other such interactions involving vitamins and minerals, and without chelation (the rendering of large organic molecules to a soluble form by combining them with metal ions) many of the essential biochemical processes of life would be impossible. Coral calcium contains all the minerals found in your body, and in very similar proportions, so that you are able to use it to maintain that all important synergism and not throw the mineral balance of your body out of balance. This is very easy to do if you take individual mineral supplements.

However, there is still more to come from this remarkable substance. It is also rich in antioxidants that spell death for free radicals. Free radicals can’t really die, because they are not living entities but molecules that have a free electron, and free electrons like to pair up with other electrons. Free radicals are therefore very aggressive when near any body cell from which they can rob an electron, and that, unfortunately, destroys the cell.

Not only that but they also oxidize molecules from which they take the electron, and if that is a low density lipoprotein, or LDL, that happens to be carrying some cholesterol to one of your arteries that needs a bit of repair work, then it will cause the LDL to deposit the cholesterol immediately and form plaques that constrict and narrow your arteries. That is called atherosclerosis and it can kill you or give you a stroke. Cholesterol is essential for good health, but once the free radicals get to work you are better without it.

However, Sango coral contains substances that prevent the free radicals from oxidizing other substances, and in so doing destroy them. That’s what antioxidants do. They prevent free radicals from oxidizing other molecules and creating all sorts of havoc with your health. Excessive amounts of free radicals have been associated with over 80 different conditions, and one of the benefits of coral calcium is that it is one of the most powerful antioxidants known.

It is not only the mineral content and antioxidant properties of coral calcium that are of benefit to the human body, but also its pH. The various fluids of your body are maintained at a specific pH, which is a measurement of the acidity or alkalinity of a fluid. This should be slightly alkaline without being caustic. If your body fluids are too acidic it becomes difficult for you to absorb minerals and vitamins, and it is essential for you maintain a balance of from around 6.4 to 7.0 Any lower than that and you will find it difficult to sleep and you will feel listless with no energy.

You can measure the pH of your body by testing your urine with pH strips available at any pharmacy. Coral calcium can be used to maintain a good pH level that allows your body to absorb the nutrients it needs, and keep you feeling not only well, but young and sprightly just like Shigechiyo Izumi did at 115 years old.

--
Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1791)

Date: May 15, 2008 01:21 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Copper

Copper is an essential trace mineral necessary for life, and it is necessary for the proper function of certain enzymes that allow certain biochemical functions of the body to take place. Without copper neither plant nor animal life would be possible.

Dietary sources include nuts, grains, seeds, beans and other vegetable protein sources. Although it is also obtained from animal sources, these tend to be rich in zinc, and for reasons that will be discussed shortly, the presence of zinc can deplete copper absorption. Other common sources are copper cooking utensils and drinking water from copper pipes. After digestion, copper is absorbed into the body through the stomach and the small intestine. It is also possible for copper to be absorbed through the skin from copper bracelets.

Once absorbed, copper is bound to albumin and taken by the blood to the liver, where it is bound to a plasma protein known as ceruloplasmin. Among the enzymes with which copper is associated as a ‘helper’ are Cytochrome C oxidase, used in the conversion of glucose to energy, Dopamine hydroxylase, an essential component in the biochemical production of adrenaline, and superoxidase dismutase, that protects against the oxidative damage of cell tissue. Of particular benefit are its anti-inflammatory and antioxidant properties, and its role in energy production. Because of its antioxidant effect, copper could well play a very important role in protecting against atherosclerosis, and cardiovascular disease, the ravaging effects of free radicals on body cells and also certain forms of cancer.

Copper is also important in electron transport, and is responsible for the blue coloration of the blood of most molluscs and many arthropods. This is because rather than hemoglobin, these animals use the copper-based hemocyanin for oxygen transport in the blood. Rather than the iron-containing hemoglobin making the blood of these creatures red as it is with mammals, theirs is blue due to the hemocyanin. Copper salts are generally green and blue, as are the blue copper proteins plastocyanin and azurin.

So how is copper used by the body? It is, after all, fairly toxic, as little as 30 grams being fatal to humans, bringing on similar symptoms to those of arsenic poisoning. It is in fact the reason for its toxicity that also renders it so useful to the body. The toxicity is largely due to the ability of copper to accept and donate electrons as it changes between oxidation states. This results in the generation of very reactive radicals that can cause severe oxidative stress. The complete reason for its toxicity has yet to be determined, but the stress caused to body cells by free radical oxidation is a very serious condition.

It is this rapid change in its oxidation state that is valuable to the enzymes with which it is associated. The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase. In doing so the copper is converted to the monovalent state.

It also helps to aid in the production of the strong antioxidant Superoxide dismutase (SOD). What this enzyme does is to catalyze the formation of oxygen and hydrogen peroxide by the dismutation of superoxide, a negative ion consisting of two oxygen atoms and a free electron, and hence a very powerful free radical. Dismutation is the simultaneous oxidation and reduction of the species, rendering the free radical relatively harmless. This type of action on free radicals is a very powerful one, and essential in the body’s fight against such free radical species that are so dangerous to animal cells.

SOD exists in more than one form, and can also contain zinc, manganese and nickel in addition to copper. The internal fluid (cytosol) of practically all eukaryotic cells (cells containing a nucleus) contain a form of Superoxide dismutase dependent on copper and zinc, while most mitochondria contain an SOD with manganese.

Another of the important uses that your body can find for copper lies in the production of hemoglobin. This is because copper is needed for the storage and release of iron to produce hemoglobin, the protein in red blood cells. It is believed that ceruloplasmin is involved in the catalytic formation of ferric iron by the oxidation of ferrous iron, so allowing the iron to be attached to a protein that transfers it round the body to enable its use in the biosynthesis of various ferrous compounds, especially of hemoglobin.

Copper bracelets are commonly worn by arthritis sufferers, and there is a scientific explanation for that. As previously inferred, it is believed to be possible to absorb copper through the skin and copper is known to be involved in the formation of collagen and is a commonly used treatment for arthritis and osteoporosis. Part of its effect on arthritis is likely due to the antioxidant effect of the SOD that helps to reduce the inflammation at arthritis sites.

Although a deficiency in copper can lead to serious health problems, an excess is also harmful. Potential conditions include neurological problems, liver damage and bone abnormalities, although deficiency is far more common because of the competition between copper and zinc. Zinc is a copper antagonist, as is iron and manganese, and copper imbalances can be moderated by the use of these as supplements.

The symptoms of a copper deficiency include fatigue, hair loss, stunted growth, anorexia and a host of other conditions. Luckily, however, a deficiency is rare and most people receive a sufficient amount of copper in their diet. Supplements are available to ensure an adequate intake.

There is still much to be learned about the interaction between copper and enzymes, and there is also a great deal still to be learned of its role in human metabolism and biochemistry than is currently known. However, sufficient is known already for us to be certain that copper is a very important trace element and that we should be certain that our intake is sufficient, given that zinc iron and manganese compete to prevent copper being absorbed by the body.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1790)

Date: May 06, 2008 05:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Grapefruit Seed Extract

Grapefruit seed extract is regarded as being natural antibiotic that is effective against a broad range of bacterial infections. It has also been used to treat parasitic infections and a range of viral infections as well as having found uses for a wide variety of medical conditions.

So what is it about grapefruit seed that is so special? Most people are acquainted with grapefruit, which as a member of the citrus family of fruits, and not to be confused with grapes which are a totally different type of plant. Grape seed extract is also a useful natural medication, but used for totally different conditions.

Because of its efficacy against parasitic and viral infections, grapefruit seed extract is very useful in treating various forms of food poisoning. But, how was this remarkable property of the simple grapefruit seed noticed? The answer to that depends very much upon what version of the story of Einstein Laureate physicist and immunologist Dr. Jacob Harich you believe.

Dr. Harich was not only a scientist but a hobby gardener in Florida, and the two versions of his story tell either that he decided to investigate why grapefruit seeds tasted so bitter, or why the grapefruit seeds in his compost heap failed to compost, or rot. Whichever story is correct, and perhaps both are, the result was the discovery that grapefruit seeds appeared to be a very effective antibiotic.

In fact it has been shown to be effective against over 800 strains of bacteria and viruses and also effective against many fungi that lead to illness in humans. Because of this it is used in cased of food poisoning that involve bacterial infection of the gastrointestinal tract. In fact during the latter part of the 1980s, grapefruit seed extract was tested against a number of known antibiotics and found to be as effective as any of them. Similar results obtained in a number of tests in the USA and elsewhere in the world, and it appears that it is an excellent treatment for the symptoms of food poisoning.

Not only that, but it has been found effective in the treatment of some immunodeficiency diseases, presumably because its antimicrobial properties does much of the work that the immune system would normally do, and so relieves it of much of its hard work. This allows the immune system to concentrate on conditions which are exacerbated by deficiencies in its operation.

Bifidobacteria and Loactobacilli are bacteria that are beneficial to the digestive system. The measure of a good broad spectrum antibiotic is that it does not affect the beneficial bacteria, and grapefruit seed extract has no effect on the former and only a mildly inhibiting effect on the latter. It is also non toxic to humans, which is another measure of a good antibiotic. You would have to drink about two pints of the extract, around 4000 time the normal dose, for the treatment to be potentially fatal.

Among the many uses of the extract are not only in controlling gastrointestinal infections, but also general fungal conditions of the skin, vaginal infections and yeast infections, and also colds and sore throats. It is also believed to support the immune system, not only by its antimicrobial properties but through its effect on intestinal health upon which much of our immune system is dependent. It can also protect patients with symptoms of AIDs and other immunodeficiency conditions from infection.

Its effect on yeast infections around the nether regions of small children has been documented, and it has also been found to be very safe to young children. In fact many mothers have it as a permanent addition to their medicine cabinet.

It is not that long ago when doctors believed all diseases to be due to bacteria or viruses. It is now becoming clear that a large proportion is actually due to fungal infections and parasites. Many conditions such as allergies, circulatory disease and some forms of arthritis have been shown to be due to fungal infections that weaken the immune system. Grapefruit seed extract has been found to be effective in treating many types of fungal disease.

In using the extract in this way, and to treat bacterial infections, it is best to start with a low dose and gradually increase it. This is because when fungi and bacteria are destroyed they release toxins, and too high a dose could result in too much toxin being produced for your body to handle. If you take it gradually you will get the same result, but without the risk of the nausea and diarrhea which the toxins can cause.

Despite all of these benefits, grapefruit extract has not been given the credit it deserves, and much research has still to be done to establish the constituents of the seed that confer these properties. Among these are known to be proanthocyanadins, a class of flavanols with strong antioxidant properties, and a diphenol hydroxybenzene complex that destroys bacteria through the cytoplasmic membrane to prevent the uptake of amino acids and cause leakage of the cell contents. Other active components are Vitamins C and E, tocopherols, limonoids and sterols, in addition to a number of important minerals.

However, there is still much work to be done, although the extract will continue to be used by many devotees for the treatment, not only of food poisoning symptoms, but also of conditions such as acne, athlete’s foot, gingivitis, cold sores, sinusitis and parasitic infections. It appears to be practically a cure-all.

There appear to be no drug interactions, although some medications do react with grapefruit juice, such as some treatments for high blood pressure. If your treatment advises you not to take grapefruit juice, then do not take grapefruit seed extract. Another factor to be aware of is that since the extract is an effective bactericide, then it could deplete the digestive tract of friendly bacteria essential for digestion. You are advised, therefore, to take a supplement of acidophilus, which is easily taken in the form of yoghurt type drinks specifically formulated or dietary supplement for the purpose.

--
Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1783)

Date: February 19, 2008 04:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benfotiamine A Natural Solution Or Miracle Substance To Control Blood Sugar?

The term "miracle" has been in use for hundreds of years when it comes to products that are claimed to aid health. Does this mean that it's always false? Not necessarily. Occasionally a seemingly "new" product will enter the spotlight and draw the attention of the public. Often, after a series of tests and trials, these products fade into oblivion because they didn't actually perform in the ways purported. There are exceptions to this rule; as with the supplement benfotiamine.

Benfotiamine is a natural solution to many problems in the human body. This product is one of nature's best sources of thiamine; or B-1. The FDA has approved this additive as a dietary supplement. Vitamin B-1 is a necessary substance in the body because it maximizes the results of your carbohydrate intake. It also helps with stress, improves your mental health and strengthens your general nervous system.

Benfotiamine is commonly found in trace amounts within such substances as roasted garlic, onions, leeks and shallots. Many years ago, a Japanese pharmaceutical company attempted to bring attention to this substance. Unfortunately, their efforts gained little traction. Recently, a physician produced a published article detailing the benefits of benfotiamine and since then the product has rapidly gained popularity.

This product has been tested for individuals with conditions pertaining to diabetes, but the full scope of clinical testing does not end there. Benfotiamine has been tested for decades for its effects and capabilities in helping all types of conditions.

For those with diabetes, this substance has been reported to alleviate sciatica as well as improve general cellular and circulation health. Neuropathy is a painful condition encountered by individuals with diabetes. There are several other related conditions that have all responded well to this supplement.

This supplement has helped many with diabetes, but also helps those without it. This supplement has also been reported to have benefits for: nerve health, improved blood pressure, fibromyalgia and has been used in the treatment of Alzheimer's disease. It has been suggested that benfotiamine contains many anti-aging properties that help the body.

Vitamin B-1 is reported to combat motion sickness. It helps in the treatment of the painful condition known as "shingles," helps lessen post-operative dental pain and even repels biting insects. B-1 is found naturally in many products including whole wheat foods, dairy products, peanuts, oatmeal and rice husks.

Benfotiamine has no known interactions with prescription medications and, in turn, helps replenish the body with thiamine. There are some prescription drugs that will cause a B-1 deficiency if no supplements are taken.

Benfotiamine is lipid-soluble (or fat-soluble) and this quality means the idea of "overdosing" is nearly impossible. It metabolizes quickly and does not build up in the human body. There are certain individuals who require a higher dose to be most effective. Those who love caffeine, who are pregnant, who smoke or drink alcohol may have a B-1 deficiency.

There are many forms of this product, but capsules seem to be the most common outside of the food groups. The effects are noted to take anywhere from two to three weeks to fully develop. If you are interested in starting a regimen of benfotiamine, or any supplement, consult your physician first.

--
Control Blood Sugar with Vitanet ®, LLC Help!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1720)

Date: January 21, 2008 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Seniors Need More Than a Multiple with Only 100 Percent of the RDA

The aging process is a gradual one. That might seem obvious, and it is, but it is the fact that it is gradual that causes people not to notice the small but significant changes in their body that are taking place. Aging is more than just the oxidation of skin cells that cause them to wrinkle, but involves specific functional cell changes, such as their ability to multiply.

As this slows down the immune system is affected, and we find it more difficult to recover from injury and disease. Oxidation becomes more prevalent and free radicals become more common as the natural antioxidants of our bodies become overwhelmed. We are less able to recover from the effects of environmental stress, such as UV radiation from the sun, pollution and the effects of heat. We find it increasingly difficult to deal with a lack of nutrition or toxins in our food from pesticides. In short, we become less capable of dealing with attack by invaders, but do not notice this gradual lack of immune response.

Age also affects our joints from the vertebrae in the neck to the joints of our toes. The net result is a compression of the bones that causes a reduction in height. We also develop more body fat and less muscle tissue, which is a significant consideration in planning the nutritional needs of the elderly. However, of more critical importance when discussion the nutritional needs of our aging population is the possibility of malabsorption.

Malabsorption is an inability of the digestive system to absorb nutrients from food, and occurs in people of any age although it tends to be more prevalent in seniors. It is predominantly due to a dysfunction of the liver, the pancreas or the small intestine that are the three major physical components of the human digestive system.

The liver produces bile that is needed to process the fats in your food, and if the bile is not delivered to the small intestine, then malabsorption is possible. The same is true of the enzymes that are produced by the pancreas These enzymes are important components in the biochemistry that allow us to absorb nutrition from our food, and since most of this absorption occurs in the small intestine, this too is essential for proper absorption. When any of these three are reduced in efficiency, as they are with advancing years, then malabsorption will occur.

When this occurs in seniors, however, it is essential that a multiple supplement with more than 100% of the RDA (Rcommended Daily Allowance) is used. This type of nutritional deficiency can be very serious at an age when so many normal biochemical processes are slowing down, and it is important that steps are taken to avoid the serious problems that can arise.

The immediate symptoms of malabsorption are diarrhea and weight loss, although the more serious longer term effects are anemia due to a deficiency in folic acid and iron and a reduction in the blood’s ability to form clots due to a deficiency in vitamin K absorption. There are others, but not all problems associated with aging are actually due to malabsorption, or even with aging.

Many of the problems associated with aging are now believed to be connected with the patient’s lifestyle and diet. Heart disease such as atherosclerosis is now known to begin earlier in life, as are many other conditions once believed to be associated with age. A loss of cognitive ability can be age related, but also due to cigarette smoking and excessive alcohol consumption. However, irrespective of all this, it is essential that the aged are provided with vitamin and mineral supplements offering more than 100% RDA.

Calcium is of particular importance for older women who are particularly prone to osteoporosis due to malabsorption of calcium from their food. At least 1000mg daily should be taken, and extra magnesium and vitamins A and E will also be necessary since they are needed for the proper absorption of calcium. The extra does not infer that all of the supplement will be absorbed, but that enough should be to help reduce the possibility of bone density problems.

The elderly are particularly prone to vitamin B deficiencies, particularly of vitamin B12, due to absorption problems and a good vitamin B complex supplement is needed. Chromium too can be seriously depleted in the aged, and this mineral is necessary to enhance the activity of insulin. It is also believed to play a part in the metabolism of carbohydrates, proteins and fats. There are no known consequences of an excess of chromium so a good supplement can be provided. It is believed that vitamin B and chromium together are required for cardiovascular and neurological health that are so important as we age.

One important supplement for the elderly is Coenzyme Q10. Many older people are prescribed drugs such as statins for the treatment of high cholesterol levels. Statins work by depressing the biochemical synthesis of cholesterol by blocking the action of mevalonate, and this is known to interfere with the metabolism of Coenzyme Q10, otherwise known as ubiquinone.

CoQ10 is essential in allowing the production of energy within the cell mitochondria by allowing electron transfer back and forth between NAD and NADH to allow the production of adenosine triphosphate (ATP). A supplement of this important enzyme is therefore essential in maintaining the energy levels of the aged who are being prescribed statins.

Almost 20% of the elderly on prescription drugs are also taking herbal remedies and supplements, and there could be an interaction between them. Anybody taking prescription drugs should consult their physicians before taking natural remedies or any form of supplement, and this is particularly true of the elderly.

However, where the elderly are safely taking a vitamin and mineral supplement, it is extremely important that this contains more than just the RDA. Absorption problems are very common in the elderly, and this excess can make sure that they receive more than they would otherwise, if not the whole recommended dosage of the particular substance involved. Better safe than sorry, especially where an excess is not known to cause harm.

--
Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1703)

Date: January 18, 2008 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Give Your Health A Boost With Silica Hydride A Powerful Antioxidant

Hydride ions are strong proton acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.

A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.

Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.

This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.

The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.

This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.

An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.

Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.

In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.

Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.

Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.

Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.

If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.

--
Buy Silica Hydride at Vitanet®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1697)

Date: December 25, 2007 11:18 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Hormone Balance for Women

The majority of women are affected by moderate-to-severe menopausal symptoms and premenstrual syndrome (PMS) at some point in their life. PMS that is clinically diagnosed consists of symptoms that are so severe and pervasive that careers, social interactions, and family lives are negatively affected. This occurs in eight to twenty percent of women in the Western world. Menopause and PMS are both characterized by a severe fluctuation or major falling of the female hormones estrogen, progesterone, and prolactin. Since many examples of women who are barely affected by natural changes exist, it can be logically inferred that female hormones are capable of remaining close to balanced, while others experience hormones that swing abruptly from one extreme to the next, causing severe mood swings. Although changes in hormone levels are the reason menopause and PMS occur, women do have some control over the severity of their symptoms.

There are many natural approaches to hormone balance along with other medical interventions that can be used either separate or together. However, one must remember that women are biologically programmed to have multiple children, which therefore, would limit the number of menstrual cycles in a lifetime. Additionally, women are now living thirty years past menopause, an experience that is relatively new. Also, a lot of the pain and anguish that is associated with menopause and PMS is actually related to obesity, high-calorie eating habits, and inactivity. Normal body weight and regular exercise often leads to mild or inconsequential PMS.

In 2002, estrogen and progesterone hormone replacement therapy, which is the standard treatment for menopausal symptoms, came under scrutiny after the publication of research that found that supplementation of estrogen significantly increases the risk for breast and ovarian cancer. Supplementing estrogen also does not protect against cardiovascular disease. As a result, US-dispensed prescriptions for estrogen declined from ninety-one million in 2001 to fifty-seven million in 2003. It has been found that a lot of the excess risk for breast and ovarian cancer was due to prescriptions being refilled indefinitely instead of hormone replacement therapy only being used at the onset of menopause. Additionally, supplemental estrogen was not paired and balanced with progesterone, causing a greater risk. Either way, the door to natural alternatives was opened wide, especially for those patients who have a family history of reproductive cancer. Natural therapy for menopause and PMS is based upon phytoestrogens.

Phytoestrogens are plant compounds that contain chemical structures which resemble estrogen. These plant compounds can exert weak estrogenic or antiestrogenic effects. Isoflavones from legumes such as soybean, red clover, licorice, as well as lignans like flaxseed and milk thistle are the most common and familiar phytoestrogens. Black cohosh has been shown to have antiestrogenic effects only. Phytoestrogens have been proven to reduce the risk for estrogen-dependent breast, uterine, and ovarian cancers as well as hot flashes, night sweats, and sleep disturbances. Although phytoestrogens do a good job at protecting women from symptoms of excess estrogen, phytoestrogens cannot replace estrogen when there isn’t enough. They don’t help with vaginal wall atrophy and dryness, thinning hair, lack of sexual desire, menopause-related urogenital itching, or infertility. For the best results, supplements of soy and red clover isoflavone should be taken 2-3 times daily. Although there are no herbal alternatives that actually raise levels of estrogen, natural medicine such as dong quai, licorice, milk thistle, ginseng, pycnogenol, and pollen for menopause and calcium, magnesium, B6, chastre tree, dong quai, and ginseng for PMS can balance existing female hormones and provide relief from symptoms.

--
Vitanet, LLC ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1682)

Date: November 02, 2007 12:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Looking For A Calcium But Not Sure Which Is Best For You?

Calcium is essential to good health, but if you are looking for calcium it can be confusing to decide in which form you take it. There are so many available and every one claims to be good for you, so why the difference? Why not just sell the best and let us all know what it is? Well, this same argument could be applied to all supplements that are sold in different forms, and also to many foodstuffs.

The supplement best for you might not be the best for the next person due to dietary requirements each persons diet is different, so it is better to learn about what is available then make your choice based upon knowledge rather than ignorance. It is not only the source of the calcium you have to bother about, but also the other vitamins that have be present to make sure that that the calcium is absorbed by the body in the way that you want it to be.

To understand that then you need to learn why the body needs calcium, other than just the bones and teeth that everybody knows about. After all, why else do we need calcium? It is only contained in bones and teeth – right? Wrong!

Although 99% of calcium is contained in your bones and teeth, 1% is contained in the blood, muscles and central nervous system. With out that 1% we would all die. Without teeth we would not. Calcium is essential for blood clotting and for the proper function of our muscles, brain and central nervous system. Calcium combines with phosphorus to create healthy bones and teeth, and is essential early in life to build up a strong skeleton. Note that phosphorus is also necessary so we also need an adequate supply of that mineral.

Calcium is essential to allow muscles to properly contract. Without that ability, muscles could not work, and a deficiency of calcium causes muscle cramps and spasms. The movement of the smooth muscles is regulated by a protein that is bound to calcium. This is just one of the uses of the calcium in the body that most people are unaware of.

Calcium also takes part in the binding process of the blood platelets during the coagulation of blood. Although most people are aware of the need for vitamin K and fibrin, in fact calcium is also essential in its interaction with the platelets in the coagulation cascade that eventually results in a blood clot that stops bleeding. Basically, without calcium, the blood could not form a clot. In addition to its effect on blood clotting, calcium also plays an essential part in the movement of ions through the membranes of nerve cells, and without it intercellular communication could not occur. Our nerve impulses would not occur and the body again would not be in a working condition.

However, the body has a way of modulating the calcium level in the blood past a minimum level needed for effective nerve cell communication, and below a certain level it can even use the calcium in the bones to divert to the more needy areas of the body. It is therefore not possible for the body to fail through a lack of calcium. The skeleton would disintegrate first. Nevertheless, nobody wants a disintegrating skeleton since that would be counterproductive to effective movement of the body, so a good source of calcium is essential for overall bodily health, not just that of the teeth and the bones.

There are many sources of calcium, but some are more suitable for absorption by the body than others. Chalk, or calcium carbonate, is an excellent source of calcium, but will fail to promote bone growth if your diet does not contain sufficient potassium, vitamin D, magnesium and strontium needed to make it work to build healthy bones. It is the most common on the shelves, and likely the cheapest, but not necessarily the best source. It is basically chalk or limestone, and only 10% of the supplement will actually become available for your body to use.

The bioavailability of a calcium supplement is a figure that indicates how much of the calcium is actually absorbed by the body during digestion. It is important that the supplement is digested and absorbed properly or the calcium will not be available for use. This availability is called the ‘bioavailability’. Calcium citrate has a bioavailabilty of 50%, but the size of the citrate part of the molecule is so large that only 10.5% of the molecule is available to the body as calcium. Not much more than the carbonate.

Calcium aspartate is highly soluble and produced by reacting calcium with aspartic acid to form the soluble salt. It is much easier to assimilate and be absorbed by the body than any of the forms above. The amino acid, aspartic acid, delivers the calcium exactly to where it is needed, where it is absorbed and used. Although a bioavailability figure is not available, it is not the amount of calcium that is significant here but the fact that it comes with its own transportation system and is immediately available where needed.

If you want to calculate the availability for yourself, find the molecular weight of the particular calcium product, and then the weight of the calcium contained within it. For example, in calcium carbonate, CaCO3, the molecular weight is 100 (40 + 12 + 3x16) and the atomic weigh of calcium is 40, so the amount of calcium present in 1000g calcium carbonate is 40% or 400g. Only 25% of calcium carbonate is absorbed, so only 10%, or 100g, of calcium is available for each 1000g supplement.

Calcium citrate on the hand (Ca3(C6H5O7)2.4H2O) has a molecular weight of 570, so the amount of calcium present is 3*40*100/570 = 21%. Since the bioavailability of calcium citrate is 50%, the amount of calcium available is only 10.5%, or 105g in 1000g citrate. You can carry out the same calculation on all the molecules if you know how much is absorbed by the body.

The bioavailability is calcium aspartate is 85%. Its molecular formula is [C4H6NO2]2Ca, and molecular weight 304. The calcium availability is therefore 40*100/304 = 13.16%. If 85% is absorbed, then 1000g provides 80% of 13.16 x 10 = 115.6g. The aspartate therefore wins it.

Amino acid chelates can also be used as a source of calcium, and its bioavailability is improved tremendously by including vitamin D and magnesium in the supplement. The bioavailability of these calcium chelates are not quoted, but is claimed to be high. Whether or not it is as high as the aspartame is debatable, though it is claimed to be.

Calcium is a very important mineral for human health, and there are several different supplements that can be used. The bioavailability of the calcium is different in each supplement, though the organic forms, calcium aspartate and amino acid calcium chelates appear to be the highest. When looking for a calcium supplement look for one with additional minerals added as mentioned above to help improve absorption and usability by the body.

--
Buy Calcium at Vitanet, LLC ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1612)

Date: October 18, 2007 03:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamin and Herbal Alternatives For Joint Health

Joint tissue breaks down and arthritis sets in for a number of reasons, and there are several natural alternatives for joint health that can be use to prevent this and to treat affected joints.

Thyroid problems can slow down the production of adrenal hormones that are responsible for the production of cortisone and cosrtisol. These are anti-inflammatories, that when unavailable or in low supply can result in joint inflammation. If you suffer joint pain in the mornings that tends to improve as the day goes on, then it is likely that is the cause since adrenal activity can improve as the day progresses.

One of the main reasons for joint tissue breakdown is osteoarthritis whereby the cartilage wears down until it fails to provide the necessary protection against impact between the bones in a joint, or against the friction generated when two bones rub together. Injuries to joints can have the same effect, whereby an injury to a hip or knee can appear to clear up and then later the cartilage wears out sooner than expected. This can take several months or many years, depending on the severity and nature of the injury concerned.

Continual wear and tear can also cause joint tissue to break down. Athletes and other sportspersons often suffer twenty years or more after retirement from their sport due to the gradual wearing down of cartilage while they were active. Once they stop, this continues to a lesser extent until the cartilage is eventually worn away sufficiently for it to stop protecting the joint.

Problems with the auto-immune system can lead to rheumatoid arthritis and inflammation of the joints. This weakens them and can eventually completely destroy the tissue. In such cases the tissues in the joint tend to swell and become extremely painful. Gout can also damage joints, especially in the big toe. This is caused through a built up of needle sharp uric acid crystals. Another cause is a deficiency in sodium and potassium in the diet that are needed to help maintain calcium in solution. When these metals are in deficiency due, for example, to an adrenal problem or some other reason, calcium can deposit right in the joints, causing undue pain.

Calcium and vitamin D deficiencies are commonly associated with arthritis sufferers, and protein deficiencies are also believed to be a contributing factor of rheumatoid arthritis, and it is also true that degenerative arthritis can accompany rheumatoid arthritis. This occurs in almost 40% of cases, and diet and nutrition are now being recognized as a major cause of both types. Deficiencies in folic acid or its natural form of folate, vitamin E, zinc and selenium have all been associated with degeneration of joint tissue, so it makes sense that a supplement of these substances can help to avoid these conditions.

Standard medical treatment, however, is for the relief of pain and reduction of inflammation through the prescribing of non-steroidal anti-inflammatory drugs (NSAIDs). Typical NSAIDs are aspirin, ibuprofen and naproxen. Although it relieves pain, paracetamol is not an anti-iflammatory. An alternative to blocking the inflammatory reponse is to help to regenerate the damaged joint tissue.

However, reducing the inflammatory response to tissue damage does not address the underlying problem, but masks it. Not only that, but there are side effects associated with the use of NSAIDs. Excessive doses can create serious gastrointestinal problems, such as bleeding, ulcer perforation and even death is possible in severe cases. Anti-inflammatories cause gastric problems in up to 20% of cases

The newer Cox-2 inhibitors act on the enzyme that causes the inflammation within the joint, and while these can be very effective, they are still masking the underlying problem. Incidentally, the Cox-2 inhibitors should not be used with NSAIDs, and both increase the possibility of a myocardial infarction or heart attack. Also, if you are taking aspirin to reduce the risk of heart problems, you should be careful not to use other NSAIDs since they can interfere with the effects of the aspirin.

More effective in the long run is to treat the conditions with substances that deal with the cause of the problem. Vitamin C, for example, improves the lubrication effect of the synovial fluid in the joints, and vitamin E is a strong antioxidant that can help to repair damaged tissue and improve the circulation within the joints. Joints have very low blood circulation levels, which is a problem when trying to direct drugs to the joint tissues. Vitamin C is also good for improving the integrity of connective tissue. Zinc, manganese and copper are also instrumental in developing strong connective tissue and helping to repair the damage done to the joints.

Horsetail is a commonly used herbal remedy that can be taken as a tea, tincture or in capsules. It is the richest natural herbal source of silicon, which is used by the body to form connective tissue and collagen. Damaged connective tissue is rapidly repaired by horsetail, and its strength and elasticity significantly improved. It is commonly used in the treatment of arthritis and osteoporosis.

Cat’s Claw is used for its beneficial effect on the immune system, and frequently used successfully to treat osteoarthritis and rheumatoid arthritis. However, this treatment is used more to help reduce the inflammatory effects of the condition than to effect a long lasting cure. Gotu Kola, also called Indian pennywort, is traditionally used for treating arthritis. The fresh leaves are effective in reducing the inflammation and pain, and help to improve the quality of life of arthritis sufferers. In Australia, it is referred to as ‘the arthritis herb’ and two leaves a day are said to be effective.

Another popular remedy is MSM (methylsulfonylmethane), although it is claimed to provide pain relief rather than a cure. Amino acids also seem to help, and L-cysteine helps promote collagen and connective tissue. It appears to work best when taken in combination with vitamin E and selenium that are powerful antioxidants. L-arginine has a similar effect in the reconstruction of joint tissue, again helping to repair damaged connective tissues.

There are therefore two approaches to treating both rheumatoid and osteoarthritis, one providing pain relief and reducing inflammation, and the other repairing the damage done to the joint tissues. Vitamins, minerals, trace minerals and herbal remedies are used in both, though it is better to use a combination that provides pain relief and also helps to regenerate strong connective tissues in the joints.

When using combinations of remedies it is important that possible interactions are understood, and you should always seek the advice of your physician when using non-prescription remedies of any kind.

--
Buy Vitamins And Herbs at Vitanet, LLC ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1597)

Date: April 21, 2007 01:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Scientific Method of Evaluating the Effectiveness of Natural Medicines

Author Dale Ericsson, M.D.; Shinian Cao, M.D.; Fred Crawford, Ph.D; Dale Haufrect, M.D. and Tommy E Hall, Jr.; USA

Introduction

It has been traditionally assumed that long chain mucopolysaccharide and other natural ingredients found in aloe vera are active only in aloe vera are active only in their unadorned and non-modified state. There is little scientific evidence, however, to support this conclusion. In fact, certain isolated components of aloe vera have pronounced specific pharmaco-therapeutic effects. The purpose of this series of experiments is to evaluate this unique method of scientifically evaluating biological and herbal products and to specifically compare fractionally distilled aloe preparation from a traditional ale preparation.

Conclusion

Utilizing the scientific method of white blood cell (T lymphocyte) culture, stimulation and metabolic turnover rates of more than 25 substances it was determined that:

1. the pivotal study had demonstrated that this type of T lymphocyte cell culture metabolic analysis is useful for evaluation the safety and efficacy of a variety of treatments in which there is only antidotal or clinical studies to support the therapeutic effect.

2. This technique of single blinded study has been employed to define the efficacy as well as compare fractionally distilled aloe vera (warren Aloe) and a traditional aloe vera product. Application of this type of blinded study to two different forms of aloe vera showed that the following conclusion may be expressed with certainty.

• Fractionally distilled aloe (Warren Aloe) of Aloe vera breaks apart the long chains of mucopolysaccharides. These long chains prevent maximum effect.
• These shorter chains are then more effective in statistically increasing activity of cell cultures in the following manner.
• Fractionally distilled Aloe produces virtually the same cellular metabolic responses as found with natural Aloe juice.
• Mitochondrial stimulation with increased fructose turnover appears greater in those patients while taking fractionally distilled aloe, while at the same time the insulin/glucose interaction is about the same with both aloe preparations.
• There appears a decreased calcium, magnesium and zinc metabolic turnover in those patients on natural aloe juice.
• Alpha lipoic acid turnover is decreased in patients taking natural aloe juice.

This data suggest that the fractionally distilled Aloe vera is bio-pharmaceutically active and provides specific changes in T cell cultures when compared to baseline and with natural aloe vera juice.

This information has been condensed. For entire report refer to EXPLORER! For the processional magazine; volume thirteen: number Two: Pages 15-19.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1525)

Date: March 24, 2007 11:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Peppermint Oil for IBS

Irritable bowel syndrome (IBS) is a painful and frequently frustrating disorder of the intestines that’s often difficult to treat. Fortunately, there are scientifically studied natural products that effectively reduce the distressing symptoms of IBS.

Q. What is IBS?

A. IBS causes crampy pain, gassiness, bloating, and alterations in bowel habits. IBS is termed a functional disorder, because when the colon is examined, there is no visible sign of disease. While IBS causes significant pain and distress, no actual damage is occurring in the intestines.

There is a wide variability in IBS. Symptoms may be mild and fairly well tolerated. Or, the pain, discomfort, and bowel dysfunction may be disabling, limiting social interactions, employment, or travel.

While some individuals with IBS have diarrhea (frequent, loose stools with an urgent need to move the bowels), others have constipation (hard, infrequent stools that are difficult to pass). And, still others may experience both. Individuals with IBS also may have painful abdominal cramps and feel an urgent need to move the bowels, but are unable to do so.

Q. What causes IBS?

A. The small intestine receives digestive material from the stomach and delivers it to the large intestine (colon). About two quarts (2,000 ml) of digestive material enter the colon from the small intestine every day. The colon absorbs water and salts from the material, which is progressively moved through the colon. This progressive movement continues until most of the fluid and salts are absorbed into the body and stool is formed. The stool passes to the left side of the colon, where it is stored until a bowel movement occurs.

Because researchers haven’t been able to find actual damage in the colon, it once was suggested that individuals with IBS have emotional problems or are overly susceptible to stress. While stress may cause symptoms of IBS to intensify, it doesn’t cause the condition.

Recent study has determined the colon muscle of an individual with IBS spasms after only mild stimulation. It’s thought the symptoms of IBS are produced by hyperactivity of the intestines. In other words, the intestines of individuals with IBS are more reactive to stressors and diet than usual. Almost everyone has experienced abdominal queasiness in response to everyday stress or certain foods. This may result in a brief bout of diarrhea or an upset stomach. However, this response is exaggerated in individuals with IBS.

Q. How prevalent is IBS?

A. IBS is very common. In fact, it’s one of the most frequent problems seen by family physicians. It’s the most common disorder diagnosed by gastroenterologists (physicians specializing in the treatment of digestive disorders). The overall prevalence rates range from 10% to 20% of the general population in most industrialized countries. As a result, the pain and disabling symptoms associated with IBS result in significant socioeconomic costs, as wall as reduction in quality of life for many individuals.

Q. What are the symptoms of IBS?

A. Normal bowel function varies from person to person. Some people move their bowels daily, while others may only have two to three stools a week. A normal bowel movement is soft, formed, and is easily passed without cramping or pain.

IBS, however, causes abdominal cramps and pain, which are often severe and disabling. Bowel movements may be irregular and alternate between diarrhea and constipation. The diarrhea may be quite loose and watery. Mucous may be passed. There is often much straining, urgency, and feeling of incomplete evacuation (emptying). Abdominal bloating and passing of gas is common. Nausea, lack of appetite, heartburn, and belching may also be present. Sleep may be disrupted resulting in fatigue and lack of energy. Understandably, persons with IBS often feel anxious and depressed.

Diagnosis of IBS is usually based on the continuous presence or recurrence of these symptoms for at least three months. Other intestinal conditions must be ruled out. These include Chron’s disease, ulcerative colitis, inflammatory bowel disease, colon cancer, inflammatory conditions of the stomach or pancreas, ulcers, infectious disease, or gastroesphageal reflux disease.

Q. Are there clinically demonstrated natural alternatives to the over-the-counter drugs prescribed by my doctor?

A. Yes, both enteric-coated peppermint oil and clown’s mustard (in combination with other herbs) have significant scientific research behind them. Both have been demonstrated to benefit individuals with IBS.

Q. What is clown’s mustard and what does it do?

A. The scientific name for clown’s mustard is Iberis amara. Other names for this herb are wild candytuft and bitter candytuft. Clown’s mustard is a white-flowering plant from Spain, where it grows in dry soil on hillsides and in cornfields. It is also grown in Britain, France, and the United States. Iberis amara is a member of the Brassicaceae family. Iberis refers to its place of origin, the Iberian Peninsula. Amara means bitter. The key components of clown’s mustard are glycosides and flavonoids that have specific actions on gastrointestinal tract tone.

Q. Is there scientific evidence that clown’s mustard benefits people with IBS?

A. There has been very impressive research on clown’s mustard (in combination with other herbs). And, it has been used with great success in Germany for many years to treat IBS and other gastrointestinal diseases.

In a study of an herbal combination containing clown’s mustard, 20 patients were given the herbal combination for three to 32 days. They all had been diagnosed with chronic functional disorders for at least one to 20 years. The symptoms the patients experienced included pressure and pain in the abdomen, belching, heartburn, vomiting, nausea, fullness, lack of appetite, constipation, and diarrhea. The patients have been treated for their problems with a variety of antacids, anti-spasmodic agents, and motility-inducing substances. For the purposes of the study, the patients stopped taking these medications and received treatment only with the herbal combination.

Abdominal pressure and pain in the abdomen was the most common of all the experienced symptoms, with 11 of the patients rating it as severe. After six days of treatment, only sic of the patients continued to rate their abdominal pain and pressure as severe. After two weeks, this symptom had completely resolved for 16 of the patients. Diarrhea had been rated as severe in five of the patients. By day 14, only one patient continued to have moderate diarrhea.

Medications prescribed and taken for cardiovascular diseases, arthritis, and autoimmune diseases often cause gastrointestinal problems. Because these conditions are chronic, these medications must be taken for a long time, often for life. With long-term use, these medications can cause erosion of the stomach lining and actual ulcers. Many of these medication-caused symptoms are similar to IBS symptoms: pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Most, if not all, of the individuals who have gastrointestinal problems caused from medications experience two or more of these IBS symptoms.

Forty patients who were taking medications for various types of cardiovascular disease and arthritis, and who are experiencing gastrointestinal problems related to their medications, were enrolled in a study. These symptoms included pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Twenty patients received clown’s mustard combined with other herbs that support gastrointestinal motility. Three days after the trial started, a significant improvement of all s symptoms was noted in those taking this combination. By day 14, abdominal pressure and pain, nausea, and heartburn were completely eliminated in the herbal combination group. Several other clinical trials that were conducted in Germany report similar results.

Q. How does this herb compare to prescription drugs?

A. A study compared clown’s mustard (combined with other herbs) to Reglan (metoclopramide), which is frequently prescribed to reduce the symptoms of IBS. While metoclopramide is a very effective medication, it also has numerous side effects. Metoclopramide can cause fatigue, anxiety, agitation, jitteriness, insomnia, yellowing of the skin or eyes, changes in vision, hallucinations, and seizures. Because of these serious side effects, metoclopramide must not be taken longer than 12 weeks.

In comparison study, 77 subjects were randomized to receive treatment of either clown’s mustard in a combination with other herbs, or metoclopramide. All subjects had pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. The subjects took 20 drops of their assigned treatment after meals three times daily. The duration of treatment was one to two weeks.

In both groups, a parallel improvement of all symptoms was observed. At no point in the study was a statistically significant difference in symptoms found. Both treatments significantly reduced pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. In short, both metoclopramide and the clown’s mustard herbal combination worked well at reducing the symptoms of IBS.

However, side effects occurred more frequently and severely in the metoclopramide group. Given the lack of differences noted between the products at reducing symptoms of IBS, it would seem sensible to choose the treatment with the fewest reported side effects and no limits on duration of use.

Q. What evidence supports use of enteric-coated peppermint oil capsules for IBS?

A. Peppermint oil has been shown to relax intestinal smooth muscle. In Great Britain, peppermint oil is currently being prescribed for IBS by physicians and it has been used as a digestive aid and to soothe upset stomachs for generations.

Peppermint oil has also been studied for use in an important examination of the colon. A colonoscopy is a procedure of viewing the interior lining of the large intestine (colon) using a colonoscope, a slender, flexible, hollow, lighted tube about the thickness of a finger. A study published in the New England Journal of Medicine supports the idea that even people who are not at risk for colon cancer should have this test. The American Cancer Society recommends that men and women at average risk of colon cancer should have a colonoscopy every 10 years, beginning at age 50.

During a colonoscopy, individuals are sedated and almost no discomfort is experienced. The insertion of the colonoscope into the rectum and up through the colon causes some spasming. This is a natural and expected event and the physician performing the exam administers medications that effectively reduce the spasms.

A recent study compared the use of peppermint oil and commonly used medications to reduce the colonic spasming in colonoscopy. The peppermint oil was introduced directly into the colon. Effective reduction of colon spasming was observed in 88% of the patients.

In a critical review and meta-analysis of peppermint oil for irritable bowel syndrome published in The American Journal of Gastroenterology, eight randomized controlled trials were identified. The studies collectively showed peppermint oil is superior to placebo in improvement of the symptoms of IBS. Because of the good results of these trials, the authors of the review urged additional study of peppermint oil in IBS.

However, straight peppermint oil is rapidly absorbed into the blood stream from the stomach. In recent studies comparing enteric-coated peppermint oil capsules and non-enteric coated oil, both preparations provided effective symptom relief. However, the studies concluded the enteric-coated capsules delivered the benefit of the peppermint oil directly to the intestines. In the treatment of IBS, enteric-coated supplemental peppermint is most definitely preferred.

In fact, an enteric-coated peppermint oil capsule containing rosemary and thyme is extremely effective in the treatment of IBS. All three of these oils are classified as volatile oils, derivatives found in plants that impart taste and aroma. The combination of peppermint, thyme, and rosemary oils in enteric-coated capsules provides significant relief in IBS-related pain.

Q. Can clown’s mustard and other herbs be taken with enteric-coated peppermint oil?

A. Yes, peppermint oil capsules and clown’s mustard can be used together. However, depending on the symptoms, individuals with IBS may want to start with one supplement and then add the other if needed.

Q. How do consumers find these formulas?

A. Fortunately, herbal combinations containing clown’s mustard and enteric-coated peppermint oil capsules are both available at health food stores, natural product supermarkets, pharmacies, and from health professionals. Most knowledgeable sales personnel and health professionals can direct consumers to the most effective products.

Q. What should customers look for when purchasing peppermint oil?

A. As mentioned before, enteric coating of the peppermint oil is extremely important. The coating prevents the oil from being absorbed in the stomach. The enteric coated-capsule moves through the stomach to the small intestine and eventually to the colon, where it is released for maximum benefit.

Q. What is the dosage for peppermint oil?

A. The German Commission E approved peppermint oil for the treatment of irritable colon. In enteric-coated form, the Commission E recommends 0.6 ml per day. Enteric-coated peppermint capsules are available.

Q. Are there side effects or other contraindications?

A. Sometimes, the enteric-coated peppermint oil capsules may cause a transient burning sensation in the rectum when moving bowls. Reducing the dose will correct this.

Individuals who must refrain from alcohol should not take clown’s mustard in an herbal tincture, which may contain alcohol.

Q. What else can IBS patients do to feel better?

A. Food allergies or food intolerance may be associated with IBS. Dairy products and certain grains may trigger a painful episode of IBS. Determining those foods that initiate the problems and eliminating them from your diet can be very helpful.

Many people report their symptoms occur after a meal. Hyperactivity of the intestine of IBS is the response. Often, the strength of this response after a meal is in direct relation to the number of calories and he amount of fat in the meal. Reducing saturated fat, limiting calories, and increasing fiber intake may be helpful.

Stress also stimulates the intestinal hyperactivity. Relaxation training may reduce some IBS symptoms. Listening to therapeutic audiotapes, hypnosis, counseling, and biofeedback all have been shown to improve the healing response in persons with IBS.

Conclusion

IBS can be painful and frustrating, capable of causing much distress. While currently there is no cure for IBS, the symptoms can be managed. The pain, abdominal discomfort, and bowel problems of IBS all respond well to treatment with the use of key herbs, including clown’s mustard, and enteric-coated peppermint oil. These herbal combinations can be both effective and safe in treating IBS. Clown’s mustard and enteric-coated peppermint oil are both effective front-line natural alternatives for IBS treatment.

--
Buy Peppermint Oil at Vitanet Discount Vitamin Store ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1494)

Date: March 08, 2007 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Revita

Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.

Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.

To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.

Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.

Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.

Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.

In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."

In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:

• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.

• 78.9% of subjects showed an increased mean value of hair diameter.

• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."

Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.

Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:

• Total Number of Hairs: Significantly Increased

• Total Number of Terminal Hairs: Significantly Greater

• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher

• Hair Follicle Activation: Intensive

In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.

Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.

Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.

The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.

Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.

Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.

Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.

Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.

Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.

If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.

Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.

The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.

Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.

After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.

Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.

MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.

The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.

MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.

Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.

The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.

According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.

The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.

Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.

Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.

The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.

Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.

Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.

Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.

L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.

The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.

Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.

In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.

Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.

Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.

Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.

Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.

After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.

This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.

Q. Is Revita safe ?

A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.

Q: Can I use hair sprays, mousses, gels, etc.?

A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.

Q: Can I have my hair colored or permed while using Revita ?

A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.

Q: What is SLS/SLES free ?

A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.

Q: Can I blow dry my hair after using Revita ?

A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.

Q: Who is a candidate for Revita ?

A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.

Q: What type of results should I expect with Revita ?

A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.

Q. Does Revita have any systemic side effects ?

A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.

Q. Does Revita work for women?

A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.

Q. I am using other topical treatments. Can I use Revita at the same time ?

A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.

Q. Do I need to use Revita for a long time ?

A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.

Q: Is stress a factor in hair loss?

A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1480)

Date: February 27, 2007 09:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Are there negative interactions with medicine?

No, there are no known negative interactions with any medication. However, you should always consult with your physician prior to altering prescription drug therapy.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1469)

Date: November 03, 2006 12:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pycnogenol: Heart, Blood Sugar and Cellular Health

Pycnogenol (pronounced pic-nojen-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France. Pycnogenol® consists of particularly bioactive flavonoid species and its purity is in strict accordance with the United States Pharmacopoeia. Pycnogenol® was initially developed 35 years ago in Europe. During the past years it evolved as one of the most thoroughly researched nutritional supplements, with over 200 studies published in peer-reviewed journals. Seventy of these studies were clinical with in total more than 4,000 patients. Pycnogenol® taken in dosages from 25mg to 300mg is well tolerated and Pycnogenol® was attributed “generally recognized as safe” (GRAS) by the FDA.

Pycnogenol® supports healthy capillaries

The “Career” of Pycnogenol® began in Europe, where it was first used to maintain vein and capillary health. Pycnogenol® has been shown to strengthen blood vessel walls, with 15 clinical trials showing fast relief from ankle and foot discomfort. A recent study with 200 passengers on long-haul flights showed that Pycnogenol® taken before departure and again during the flight supports foot comfort and healthy circulation. Travelers typically comment that with Pycnogenol® it is much easier to put shoes on again upon arrival. Clinicians in Germany discovered that Pycnogenol® also supports healthy capillaries in the eyes. Retinal capillaries may be affected by imbalanced blood sugar levels. In a multi-center field study with 1169 subjects Pycnogenol® supported healthy capillaries in the retina and improved visual acuity to some extent.

Pycnogenol® benefits the cardiovascular system

More detailed investigation of the interaction of Pycnogenol® with blood vessel walls at the University of Florida, Tampa led to an amazing discovery. Pycnogenol® stimulates an enzyme in blood vessel walls that is responsible for generating the most important vascular mediator, known as “nitric oxide” (NO). NO triggers relaxation of the arteries and supports clear blood flow. Hence, NO is the body’s mediator for maintaining healthy blood pressure levels and circulation. NO plays such an important function for cardiovascular health that Dr. Louis Ignarro (UCLA) and his co-workers received the Nobel Prize for this discovery in 1987.

A number of factors, including aging, can interfere with the body’s efficient production of NO. Supplementation with Pycnogenol® for four weeks was shown to restore NO production and improve blood supply to the fingertips of elderly people in a Japanese study. Microscopic evaluation of blood vessel diameter at the root of fingernails showed an increased diameter of capillaries allowing better blood perfusion. Specific sensors applied to the legs showed increased oxygen and decreased carbon dioxide presence. Better blood, nutrient and oxygen supply with Pycnogenol® benefits everybody. Italian researchers were able to show that regular intake of Pycnogenol® helps defy muscle cramps and minor pain in athletes.

The relaxation of arteries has a favorable effect on blood pressure. In two clinical studies Pycnogenol® taken for at least eight weeks was found to significantly support normal blood pressure.

Pycnogenol® stimulated NO generation directly translates into clear blood flow. This was first demonstrated at the University of Arizona, Tucson in smokers. Pycnogenol® dose-dependently, starting at a single dose of 25mg, countered the typical effects of cigarette smoking on the blood. Also, Italian vascular specialists found that Pycnogenol® supported the circulation of individuals on flights between New York and London.

Pycnogenol® supports healthy blood sugar levels

Pycnogenol® can support normal glucose levels when taken as part of a healthy diet and lifestyle plan. A clinical investigation has confirmed the significant glucose-lowering effect of Pycnogenol®. It was noted that Pycnogenol® did not affect insulin levels. Pycnogenol® appears to facilitate previously insulin-resistant cells to uptake sugar from the blood stream by yet unknown mechanisms.

Pycnogenol® limits cellular irritation

Two clinical studies carried out in Germany this year with student volunteers demonstrated that Pycnogenol® has a potent effect in preventing cellular irritation. Pycnogenol® inhibits a molecular “main-switch” in immune cells that triggers the onset of cellular irritation in any part of the body. Moreover, Pycnogenol® was found to inhibit so-called COX enzymes, which are involved with minor pain-sensation related to cellular irritation.

Pycnogenol® sooths menstrual pain

Japanese gynecologists discovered in 1999 that regular supplementation with Pycnogenol® soothes the normal discomfort of menstrual pain, particularly during cramping. Another clinical investigation of 47 women in year 2004 confirmed the effect of Pycnogenol® in addressing menstrual pain. This year a double-blind, placebo-controlled, multi-center field study with 116 women again confirmed these results. Pycnogenol® is not suitable for on-demand relief during menstruation. The studies show that Pycnogenol® reached highest efficacy when taken regularly for months.

Pycnogenol® helps to support respiratory health

Challenges to normal respiratory function may result from incidents the immune system perceives as harmful. Pycnogenol® offers valuable help in supporting respiration due to its immune-modulating effect and its ability to limit cellular irritation. A study at the University of Arizona found that Pycnogenol® supports clear breathing and lowers mediators of cellular irritation in the blood stream. More recently, a placebo-controlled clinical study at the University of California, Loma Linda described how Pycnogenol® supported healthy respiration in 60 children aged 6-18 years. Pycnogenol® needs to be taken continuously for prolonged periods of time for maximum benefit to the respiratory system.

Pycnogenol® is investigated in clinical trials all over the world. New findings are posted on the website www.pycnogenol.com.

Frank Schonlau Ph.D. is a biochemist who has spent nine years in medical research at the University Clinic of Munster Germany. His area of expertise covers vascular disorders, inflammation and dermatology. He has published more than 20 studies and review articles in the medical literature. Since entering the dietary field in 1999 he was involved in numerous studies on Pycnogenol® and communication of new health discoveries.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1414)

Date: February 12, 2006 03:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Best Alpha Lipoic 35!

Benefits Supports the Body’s Defense Against Free Radicals* Recycles Antioxidant Nutrients such as Vitamin C and Vitamin E* Helps Maintain a Healthy Blood Sugar Level when used as part of the diet* Alpha-lipoic Acid––the "Ideal Antioxidant" The antioxidant potential of a substance is based on a number of criteria, including: 1) Ability to quench specific free-radicals. 2) Ability to bind or "chelate" metal ions that can generate free radicals. 3) Supports function of other antioxidants. 4) Absorption/bioavailability. 5) Concentration in tissues, cells and extra cellular fluids. 6) Ability to function as an antioxidant in fatty and watery environments. The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes. As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3 1) ALA is easily absorbed when consumed orally. 2) ALA is readily converted to DHLA in various tissues. 3) As a pair, ALA and DHLA neutralize superoxide, hydroxyl, peroxyl, and hypochlorus radicals. 4) ALA and DHLA form stable complexes with metal ions such as iron, manganese, copper and zinc ions. 5) ALA and DHLA scavenge free radicals in fatty environments and watery environments. 6) DHLA recycles other important antioxidants. DHLA-regenerates vitamin C, vitamin E and glutathione Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants. DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7 Alpha-lipoic Acid and Blood Sugar Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10 Safety Suggested Adult Use: One to six capsules daily with food. Alpha-lipoic acid is considered safe, and no adverse effects have been seen with long-term supplementation.1 Scientific References 1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50. 2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63. 3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31. 4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21. 5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561. 6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637. 7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87. 8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4. 9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14. 10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804. -- Buy Doctors Best Vitamins at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1217)

Date: December 13, 2005 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coenzyme Q10 and Cardiovascular Health.

CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!

CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.

CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.

As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”

“The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.

Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1012)

Date: December 08, 2005 04:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butterbur Extract Fact Sheet

Butterbur Extract Fact Sheet

LIKELY USERS: People wanting to support healthy blood flow to the brain and healthy neurological function 1-6,10 Those maintaining normal seasonal immune responses 7-10

KEY INGREDIENTS: 75 mg of Guaranteed Potency Butterbur Root (Petasites hybridus) Extract, min. 15 Sesquiterpenes as Petasines; 200 mg of Feverfew Leaf (Tanacetum parthenium) min. 0.4% Parthenolides

MAIN PRODUCT FEATURES: Butterbur (Petasites hybridus) is a native shrub of Europe, North America, and Asia that has been used by herbalists for centuries. Modern scientific studies have demonstrated that Butterbur supports healthy blood flow to the brain and healthy neurological function.1-6, 10 In addition, Butterbur may help to maintain balanced seasonal immune responses.7-10 In a synergistic base of guaranteed potency Feverfew leaf.11-26

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW Butterbur is free of harmful levels of Pyrrolizidine Alkaloids (PAs), the undesirable compounds naturally found in Butterbur, so it is safe to use regularly.

SERVING SIZE & HOW TO TAKE IT: Take one VCap one to three times per day, or as directed by your physician.

COMPLEMENTARY PRODUCTS: Magnesium, Ulcetrol, B-2, B-12, Fish Oil (EPA, DHA), SAM-e, Ginger, Ginkgo Biloba

CAUTIONS: None.

SPECIFIC: Do not discontinue use abruptly; taper off use if discontinuing. Discontinue use at least 14 days before surgery or oral surgery. Use with caution if you have ragweed allergies or blood disorders and let your physician know that you plan to use it before you take it. May be contraindicated for pregnant women.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

1. Diener HC, Rahlfs VW, Danesch U (2004) The First Placebo-Controlled Trial of a Special Butterbur Root Exract for the Preventio of Migraine: Reanalysis of Efficacy Criteria. Eur Neurol 51:89-97.
2. Lipton RB, Gobel H, Einhaupl KM, Wilks K, Mauskop A (2004) Petasites hybridus root (butterbur) is an effective preventative treatment for migraine. Neurology 63:2240-2244.
3. Pothmann R, Danesch U (2005) Migraine Preventiuon in Children and Adolescents: Results of an Open Study With a Special Butterbur Root Extract. Headache 45:196-203.
4. Rapaport AM, Bigal ME (2004) Perventive migraine therapy: what is new. Neurol Sci 25:S177-S185.
5. Wu SN, Chen H, Lin YL (2003) The mechanism of inhibitory actions of S-petasin, a sequiterpene of Petasites formosanus, on L-type calcium current in NG108-15 neuronal cells. Planta Med 69(2):118-124.
6. Wang G-J, Wu X-C, Lin Y-L, Ren J, Shum AY-C, Wu Y-Y, Chen C-F (2002) Ca2+ channel blockin effect of iso-S-petasin in rat aoritic smooth muscle cells. Eur J Pharmacol 445(3):239-45.
7. Lee DKC, Carstairs IJ, Haggart K, Jackson CM, Currie GP, Lipworth BJ (2003) Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis. Clin Exp Allergy 33:882-886.
8. Lee DKC, Haggart K, Robb FM, Lipworth BJ (2004) Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids. Clin Exp Allergy 34:110-114.
9. Lee DKC, Gray RD, Robb FM, Fujihara S, Lipworth BJ (2004) A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis. Clin Exp Allergy 34:646-649.
10. (No Author) (2001) Petasites hybridus (Butterbur). Alt Med Rev 6(2):207-209.
11. Hayes NA, et al. The Activity of Compounds Extracted from Feverfew on Histamine Release from Rat Mast Cells. J Pharm Pharmacol. Jun1987;39(6):466-70.
12. 2 Groenewegen WA, et al. A Comparison of the Effects of an Extract of Feverfew and Parthenolide, a Component of Feverfew, on Human Platelet Activity In-vitro. J Pharm Pharmacol. 1990;42(8):553-57.
13 Capasso F. The Effect of An Aqueous Extract of Tanacetum parthenium L. on Arachidonic Acid Metabolism by Rat Peritoneal Leucocytes. J Pharm Pharmacol. Jan1986;38(1):71-72.
14. 4 Bejar E. Parthenolide Inhibits the Contractile Responses of Rat Stomach Fundus to Fenfluramine and Dextroamphetamine but not Serotonin. J Ethnopharmacol. Jan1996;50(1):1-12.
15. 5 Prusinski A, Durko A, Niczyporuk-Turek A. [Feverfew as a Prophylactic Treatment of Migraine]. Neurol Neurochir Pol. 1999;33(Suppl 5):89-95.
16. 6 Barsby RW, et al. Feverfew Extracts and Parthenolide Irreversibly Inhibit Vascular Responses of the Rabbit Aorta. J Pharm Pharmacol. Sep1992;44(9):737-40.
17. 7 Pittler MH, Vogler BK, Ernst E. Feverfew for Preventing Migraine (Cochrane Review). Cochrane Database Syst Rev. 2000;(3):CD002286.
18. 8 Pattrick M, et al. Feverfew in Rheumatoid Arthritis: A Double-blind, Placebo Controlled Study. Ann Rheum Dis. 1989;48:547-49.
19. 9 Makheja AM, et al. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostaglandin Leukotri Med. 1982;8:653-60. 20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada . Ottawa , Canada
20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada. Ottawa, Canada.
21. 14 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press; 1996:119-21.
22. 15 PDR for Herbal Medicines, 2nd ed. Montvale , NJ: Medical Economics Company; 2000:307.
23. 16 Pribitkin ED. Herbal therapy: what every facial plastic surgeon must know. Arch Facial Plast Surg. Apr2001;3(2): 127-32.
24. 17 Schmidt RJ. Plant dermatitis. Compasitae. Clin Dermatol. Apr1986;4(2):46-61.
25. 18 Heck AM, et al. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. Jul2000;57(13): 1221-7.
26. 19 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London : The Pharmaceutical Press; 1996:119-21.

--
Butterbur at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=996)

Date: December 07, 2005 02:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: TMG Fact Sheet

TMG Fact Sheet

LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.

MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.

TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.

Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.

ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.

TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.

DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.

SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.

COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.

People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.

This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

General:

Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791

Methylation:

Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review].

Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30.

Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review].

Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.

Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.

Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.

Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

Homocysteine:

Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.

Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361

Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203

Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266

Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].

van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.

Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.

Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.

Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499

Liver function:

Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].

Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.

Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.

Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329

Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277

Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.

Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887

Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612

Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.

McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907

Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.

Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439

Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].

Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644

Autism & Seizures:

Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.

Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.

Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.

Immunity:

Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.

Safety:

Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=988)

Date: December 07, 2005 01:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Allibiotic CF Fact Sheet

Allibiotic CF Fact Sheet

LIKELY USERS: People seeking support of the immune system and intestinal flora

KEY INGREDIENTS: Allicin (“AlliSure” patented, stabilized allicin from fresh garlic); Olive Leaf Extract (Olea Europaea with 18% minimum Oleuropein content); Elderberry extract, from fruit/berry, 60:1 concentrate (equivalent to 2,500 mg. of fresh berries of Sambucus nigra); Oil of Oregano (wild oregano from Origanum vulgare) ImmunEnhancer AG (trademarked Arabinogalactan from Larch Tree, Larix occidentalis)

MAIN PRODUCT FEATURES: AlliSure is the clinically tested, patented and stable form of allicin. Not allicin potential, but actual allicin. Allicin represents the immune supporting nutrients of raw garlic, and is chemically similar to penicillin, though with different physical properties. AlliSure shares garlic’s abilities to help maintain healthy cholesterol and blood pressure levels, and also has been shown to raise levels of a key T cell to enhance immune system function. Like raw garlic, AlliSure has antimicrobial properties linked to its ability to react with sulfur-containing metabolic enzymes. Allicin is also shown in studies to play a role in controlling blood sugar and abnormal cell growth.

Black Elderberries have strong antioxidant properties, containing flavonoids like anthocyanidins. They have been studied in relation to inhibition of viral replication and of minor inflammations.

Olive Leaf has been used as an antioxidant, cholesterol and blood viscosity regulator, and vasodilator. But its most important use has been as a way to help the body deal with undesirable organisms in the vital respiratory and intestinal areas.

Oil of Oregano (wild oregano, wild marjoram) contains carvacrol and thymol, which are responsible for much of its antimicrobial activities. It also has some anti-inflammatory effects.

Arabinogalactan from Larch tree bark (ImmunEnhancer AG) can help speed the immune system’s response to undesirable organisms and is often compared to Echinacea. It has also been shown to promote the growth of beneficial intestinal bacteria.

ADDITIONAL PRODUCT INFORMATION: Patented and trademarked ingredients enhance quality controls and have clinical research. Rosemary Oil provides antioxidant protection for the capsule contents. Enteric coating protects the capsule from stomach acid to deliver its contents past the stomach. This helps to assure full potency and reduces the possibility of the oils repeating.

SERVING SIZE & HOW TO TAKE IT: One softgel twice daily, preferably with meals. Try one before using the full dose.

COMPLEMENTARY PRODUCTS: Probiotics, Antioxidants, D-Flame

CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Discontinue use if any uncomfortable side effects occur. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

ALLICIN:

Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Adv Ther. 2001 Jul-Aug;18(4):189-93. (AlliSure was used in this study.)

Abramovitz D, Gavri S, Harats D, Levkovitz H, Mirelman D, Miron T, Eilat-Adar S, Rabinkov A, Wilchek M, Eldar M, Vered Z. Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet. Coron Artery Dis. 1999 Oct;10(7):515-9. PMID: 10562920

Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997 Oct;41(10):2286-8. PMID: 9333064

Cellini L, Di Campli E, Masulli M, Di Bartolomeo S, Allocati N. Inhibition of Helicobacter pylori by garlic extract (Allium sativum). FEMS Immunol Med Microbiol. 1996 Apr;13(4):273-7. PMID: 8739190

Chowdhury AK, Ahsan M, Islam SN, Ahmed ZU. Efficacy of aqueous extract of garlic & allicin in experimental shigellosis in rabbits. Indian J Med Res. 1991 Jan;93:33-6.

Eilat S, Oestraicher Y, Rabinkov A, Ohad D, Mirelman D, Battler A, Eldar M, Vered Z. Alteration of lipid profile in hyperlipidemic rabbits by allicin, an active constituent of garlic. Coron Artery Dis. 1995 Dec;6(12):985-90. PMID: 8723021

Elkayam A, Mirelman D, Peleg E, Wilchek M, Miron T, Rabinkov A, Oron-Herman M, Rosenthal T. The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Am J Hypertens. 2003 Dec;16(12):1053-6. PMID: 14643581

Feldberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Sundstrom DC, Thompson NH. In vitro mechanism of inhibition of bacterial cell growth by allicin. Antimicrob Agents Chemother. 1988 Dec;32(12):1763-8.

Focke M, Feld A, Lichtenthaler K. Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase. FEBS Lett. 1990 Feb 12;261(1):106-8.

Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. Nutr Cancer. 2000;38(2):245-54. PMID: 11525603

Patya M, Zahalka MA, Vanichkin A, Rabinkov A, Miron T, Mirelman D, Wilchek M, Lander HM, Novogrodsky A. Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Int Immunol. 2004 Feb;16(2):275-81. PMID: 14734613

Rabinkov A, Miron T, Mirelman D, Wilchek M, Glozman S, Yavin E, Weiner L. S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):144-153. PMID: 11118647

Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998 Feb 2;1379(2):233-44. PMID: 9528659

Sela U, Ganor S, Hecht I, Brill A, Miron T, Rabinkov A, Wilchek M, Mirelman D, Lider O, Hershkoviz R. Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Immunology. 2004 Apr;111(4):391-9. PMID: 15056375

Shadkchan Y, Shemesh E, Mirelman D, Miron T, Rabinkov A, Wilchek M, Osherov N. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J Antimicrob Chemother. 2004 May;53(5):832-6. Epub 2004 Mar 24. PMID: 15044429

Tsai Y, Cole LL, Davis LE, Lockwood SJ, Simmons V, Wild GC. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Planta Med. 1985 Oct;(5):460-1. PMID: 3001801

Uchida Y, Takahashi T, Sato N. [The characteristics of the antibacterial activity of garlic (author's transl)] Jpn J Antibiot. 1975 Aug;28(4):638-42. PMID: 1099271

Yasuo Yamada and Keizô Azuma. Evaluation of the In Vitro Antifungal Activity of Allicin. Antimicrob Agents Chemother. 1977 April; 11(4): 743–749.

ELDERBERRY:

Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 423.

Gruenwald J, Brendler T, Jaenicke C, et al. (eds). PDR for Herbal Medicines. Montvale, NJ: Medical Economics, 1998, 1116–7.

Mascolo N, Autore G, Capasso G, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987;1:28–31.

Murkovic M, Abuja PM, Bergmann AR, et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. Feb2004;58(2):244-9.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press, 1996, 104–5.

Yesilada E. Inhibitory Effects of Turkish Folk Remedies on Inflammatory Cytokines: Interleukin-1Alpha, Interleukin-1Beta and Tumor Necrosis Factor Alpha. J Ethnopharmacol. Sept1997;58(1):59-73. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radical Biol Med 2000;29:51–60.

Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995;1:361–9.

OLIVE LEAF EXTRACT:

American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.

Bennani-Kabchi N, et al. Effects of Olea europea var. oleaster leaves in hypercholesterolemic insulin-resistant sand rats. Therapie. Nov1999;54(6):717-23.

Bisignano G, et al. On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. J Pharm Pharmacol. Aug1999;51(8):971-4. Gonzalez M, et al. Hypoglycemic activity of olive leaf. Planta Medica. 1992;58:513-515. Visoli F, et al. Oleuropein protects low density lipoprotein from oxidation. Life Sciences. 1994;55:1965-71. PDR for Herbal Medicines, 2nd edition. Montvale, NJ: Medical Economics Company; 2000:557.

Petroni A, et al. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.Thromb Res. Apr1995;78(2):151-60. Pieroni A, et al. In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves. Pharmazie. Oct1996;51(10):765-8. Zarzuelo A, et al. Vasodilator effect of olive leaf. Planta Med. Oct1991;57(5):417-9. OREGANO OIL (OIL OF OREGANO, WILD OREGANO, WILD MARJORAM):

Dorman HJ, et al. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. Feb2000;88(2):308-16. Force M, et al. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. May2000;14(3):213-4.

Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999;86:985–90.

Kelm MA, Nair MG, Strasburg GM. Antioxidant and Cyclooxygenase Inhibitory Phenolic Compounds from Ocimum sanctum Linn. Phytomedicine. Mar2000;7(1):7-13. Lamaison JL, et al. Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv. 1991;66(7):185-8.

Ponce MM, Navarro AI, Martinez GMN, et al. In vitro effect against Giardia of 14 plant extracts. Rev Invest Clin 1994;46:343–7 [in Spanish].

Stiles JC, Sparks W, Ronzio RA. The inhibition of Candida albicans by oregano. J Applied Nutr 1995;47:96–102.

Tantaoui EA, Beraoud L. Inhibition of growth and aflatoxin production in Aspergillus parasiticus by essential oils of selected plant materials. J Environ Pathol Toxicol Oncol 1994;13:67–72. ImmunEnhancer AG (Larch tree Arabinogalactan)

Corado J, et al. Impairment of Natural Killer (NK) Cytotoxic Activity in Hepatitis C Virus (HCV) Infection. Exp Immunol. 1997;109:451-457. Currier NL, Lejtenyi D, Miller SC. Effect over time of in-vivo administration of the polysaccharide arabinogalactan on immune and hemopoietic cell lineages in murine spleen and bone marrow. Phytomedicine. 2003 Mar;10(2-3):145-53. PMID: 12725568

Egert D, et al. Studies on Antigen Specificity of Immunoreactive Arabinogalactan Proteins Extracted from Baptisia tinctoria and Echinacea purpurea. Planta Med. 1992;58:163-165. Gonda R, et al. Arabinogalactan Core Structure and Immunological Activities of Ukonan C, An Acidic Polysaccharide from the Rhizome of Curcuma longa. Biol Pharm Bull. 1993;16:235-238. Hagmar B, et al. Arabinogalactan Blockade of Experimental Metastases to Liver by Murine Hepatoma. Invasion Metastasis. 1991;11:348-355. Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev. 1999 Apr;4(2):96-103. Review. PMID: 10231609

Kim LS, Waters RF, Burkholder PM. Immunological activity of larch arabinogalactan and Echinacea: a preliminary, randomized, double-blind, placebo-controlled trial. Altern Med Rev. 2002 Apr;7(2):138-49. PMID: 11991793

Levine PH, et al. Dysfunction of Natural Killer Activity in a Family With Chronic Fatigue Syndrome. Clin Immunol Immunopathol. 1998;88:96-104. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr. 2001 Aug;20(4):279-85. PMID: 11506055

Rolfe RD. The Role of Probiotic Cultures in the Control of Gastrointestinal Health. J Nutr. Feb2000;130(2S Suppl):396S-402S.

Salyers AA, Vercellotti JR, West SE, Wilkins TD. Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon. Appl Environ Microbiol. 1977 Feb;33(2):319-22. PMID: 848954

Uchida A. Therapy of Chronic Fatigue Syndrome. Nippon Rinsho. 1992;50:2679-2683.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=987)

Date: October 13, 2005 05:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Alpha Lipoic Acid

Benefits of Alpha Lipoic Acid

Helps Maintain a Healthy Blood Sugar Level when used as part of the diet*

Alpha-lipoic Acid––the "Ideal Antioxidant"

The antioxidant potential of a substance is based on a number of criteria, including:
1) Ability to quench specific free-radicals.
2) Ability to bind or "chelate" metal ions that can generate free radicals.
3) Supports function of other antioxidants.
4) Absorption/bioavailability.
5) Concentration in tissues, cells and extra cellular fluids.
6) Ability to function as an antioxidant in fatty and watery environments.

The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.

As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3
1) ALA is easily absorbed when consumed orally.
2) ALA is readily converted to DHLA in various tissues.
3) As a pair, ALA and DHLA neutralize superoxide, hydroxyl, peroxyl, and hypochlorus radicals.
4) ALA and DHLA form stable complexes with metal ions such as iron, manganese, copper and zinc ions.
5) ALA and DHLA scavenge free radicals in fatty environments and watery environments.
6) DHLA recycles other important antioxidants.

DHLA-regenerates vitamin C, vitamin E and glutathione

Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants.

DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7

Alpha-lipoic Acid and Blood Sugar

Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10

Scientific References

1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50.

2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63.

3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31.

4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21.

5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561.

6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637.

7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87.

8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4.

9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14.

10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804.

--
Discount Herbs at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=840)

---

Sytrinol can lower Cholesterol by 27% - 34%

Date: September 20, 2005 09:56 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Sytrinol can lower Cholesterol by 27% - 34%

Sytrinol – MultiPronged Heart Health

According to the American Heart Association, more than 60 million Americans suffer from on of more forms of cardiovascular imbalances. When we add in those individuals with blood cholesterol concerns, we see over 100 million Americans who may be in need of specific diet and lifestyle recommendations for achieving and maintaining heart health.

Aside from the generalized recommendations that we typically hear for heart health (lose weight, exercise more, and eat less fat and more fruits and vegetables) There are a number of potentially beneficial dietary supplements that may help to maintain cholesterol levels in the normal range. Among supplements there is a wide range of safety and efficacy between products—but a newer product called Sytrinol stands out for its clinical effectiveness.

Sytrinol is a patented blend of polymethoxylated flavones (from citrus) and tocotrienols (from palm fruit). One of the factors that sets Sytrinol apart from existing natural products for heart health is its multipronged approach to controlling multiple factors related to overall heart health—including control of cholesterol, cellular irritation, oxidation, triglycerides, and others.

Cholesterol Conundrum

While it is unarguable that cholesterol is an important contributor to overall heart health, it couldn’t be further from the truth that cholesterol is the “only” or even the most important factor when it comes to protecting your heart. Did you know that approximately HALF of all serious heart challenges each year are experienced by people with NORMAL cholesterol levels? If Cholesterol is not to blame, then what is?

In addition to total cholesterol levels (the “number” that you may know as 200 to 240 of other values in “mg/dl” units), we know how that LDL and HDL matter a lot (Low-density lipoprotein—the “bad” cholesterol, and High-density lipoprotein—the “good” cholesterol). We also know that some forms of the bad and LDL can be “Badder” than others—specifically those with lots of structural protein called “apolipoprotein B” (which tends to encourage LDL cholesterol to become embedded in your blood vessel linings—bad!). In addition to our total cholesterol, LDL, HDL, and the various apoproteins, we also need to know our triglyceride levels, our levels of cellular irritation, what our free radical load looks like, and what our antioxidant defenses are. Sytrinol addresses each of these important aspects of heart and health simultaneously.

The Sytrinol Solution

Polymethoxylated Flavones (PMFs) in Sytrinol are just what they sound like – flavonoid compounds with extra methoxy groups compared to “regular flavones. Like all flavonoids, the PMFs deliver potent antioxidant activity, but the PMF version is about three times more potent in its ability to address cholesterol levels (20% - 30% reduction in clinical Studies). The two primary PMFs are nobiletin and tangeretin.

In addition to the PMFs, Sytrinol contains palm tocotrienols—one of the most potent antioxidant nutrients known. An interesting effect of tocotrienols is a reduction in cholesterol synthesis in the liver—by a mechanism similar to (but safer than) the commonly utilized mechanism of inhibition of the HMG-CoA Reductase Enzyme.

Sytrinol is known to work via several unique mechanisms to reduce triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL). First, by reducing DGAT activity (Diacylglycerol acetyl transferase) and increasing liver PPAR (Peroxisome porliferator-activated receptor)—Sytrinol can reduce overall synthesis of TG (DGAT inhibition). The overall effect is to reduce TG levels in the blood by two complementary mechanisms.

In terms of LDL effects, Sytrinol also reduces both Apolipoprotein B levels (ApoB—needed for the synthesis of LDL particles) and MTTP levels (microsomal triglyceride transfer protein-needed to transfer fat into the new LDL particles). By reducing levels of both these tructural LDL components, Sytrinol reduces overall LDL levels, and thus total cholesterol levels, in the blood.

The clinical results behind Sytrinol are impressive—showing a reduction in levels of total, LDL, and triglycerides by 27% - 34% within 4 weeks. In one of these studies, ApoB levels were reduced (suggesting reduced LDL) and ApoA1 levels were increased (suggesting increased HDL)—as would be expected based on the biochemistry of PMFs and tocotrienols.

Sytrinol is also wonderfully safe—and at the effective dose of 300mg daily, users will benefit from its multipronged effects. One aspect of Sytrinol safety that I especially like is the finding that, unlike some flavonoids like naringin from grapefruit, there are no known risks of drug interactions with the form of citrus derived PMFs found in Sytrinol (certain grapefruit flavonoids can interfere with liver enzymes needed to metabolize many prescription drugs).

Summary

Not since Red Yeast Rice was removed from the market by the FDA, have we had a truly effective, multimechanism solution for cholesterol control (and nearly total heart health). There are certainly other options for addressing heart health and cholesterol levels, but among the available choices, such as policosanol, guggulipid, niacin, and plant sterols, we’re looking at about half the cholesterol-lowering ability (10% - 15% in most cases) compared to Sytrinol. If youre in the “borderline” zone of cholesterol levels (about 240mg/dl and below), you should absolutely consider Sytrinol to keep your cholesterol levels under control.

References

Kurowska EM, manthey Ja. Hypolipidemic effects of absorption of citrus polymethoxylated flavones in hamsters with diet-included hypercholesterolemia. J Argic food chem.. 2004 may 19;52(10):2879-86.

Kurowska EM, manthey Ja, Casaschi A, Theriault AG. Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, Tangeretin. Lipids 2004 feb;39(2):143-51.

Manthey JA, Grohmann K, Montanari A, Ash K, Manthey CL, Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human moncytes. J Nat Prod. 1999 mar;62(3)441-4.

Mora A, Paya M, rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem Parmacol. 1990 Aug 15;40(4):797-7.

Takanaga H, Ohnishi A, Yamada S, Matsuo H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol exp. Ther. 2000 Apr;293(1):230-6.

By: Shawn M. Talbott, PH.D.

Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=791)

---

Source Naturals - Scientific Formulation

Date: August 20, 2005 11:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals - Scientific Formulation

“Formulation is an art—based on science, traditional approaches, and a thorough understanding of an issue. My prime responsibility is to design and create formulas that are comprehensive and effective. I strongly believe in supporting the whole person and in empowering people to take control of their health through nutrition and self-education.” –Linda Meltzer, C.N., Research Specialist

Scientific Formulation

Formulation at Source Naturals begins with our highly trained research and product development staff. Our researchers conduct an exhaustive review of the scientific literature on each nutrient or botanical.

Their investigation covers traditional approaches, modern medical interventions, and current studies.

Dosage, delivery method, optimal ratios and combinations of ingredients, biochemical interactions of nutrients and herbs, the quality and form of raw materials—all are scrutinized in a quest for product efficacy. Members of our research, product development, quality control, regulatory affairs and manufacturing groups regularly attend quality circle meetings. At these meetings, team members contribute their particular expertise to resolve complex issues in the development of formulas, labels and literature.

Source Naturals researchers have all the scientific knowledge and tools of the supplement industry at their fingertips— but they also have something other companies may lack. Our expert formulators understand the need to address nutritional symptoms* at their root cause: body system imbalances. The ultimate expression of this quality-assured formulation method is our line of Bio-Aligned Formulas™. These products address nutritional symptoms* by supporting the multiple body systems involved.

Only by this holistic method of bringing alignment to your interdependent body systems can vibrant health be attained.

Source Naturals labels and literature explain the structure-function benefits of each product. Corroborated research backs these statements, from authoritative sources such as biochemistry texts, respected journals, herbal pharmacopoeia and homeopathic Materia Medica.

Our labeling and literature are reviewed by attorneys who specialize in FDA law. This ensures that claims are accurate and appropriate according to the Dietary Supplement Health and Education Act (DSHEA).

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=736)

---

Strontium Bone Maker 60 VC - Strengthen Bones

Date: July 27, 2005 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Strontium Bone Maker 60 VC - Strengthen Bones

Benefits

Helps maintain strong, healthy bones.*

In Vitro and Animal Studies

Strontium is a bone-seeking mineral incorporated by ionic substitution for calcium onto the crystal surface of bone.2 In the test-tube (in vitro), strontium inhibits the activity of osteoclasts, bone cells that break down bone, or “resorb” bone as part of the normal bone remodeling process.3 The effect of strontium, in the form of strontium ranelate (a salt of strontium and ranelic acid), was studied in monkeys over a six-month period. Strontium altered the remodeling of bone in the monkeys, resulting in decreased bone resorption with a concomitant maintenance of bone formation. A trend toward increased volume of osteoid, the organic matrix of bone, was observed, although this was not associated with defects in bone mineralization.4 In another animal study, monkeys fed strontium at high doses for six weeks showed a marked increase in bone strontium content. No harmful effects on bone mineral chemistry or structure occurred.5 At low doses, strontium has been shown to increase the number of bone forming sites in thighbones of adult rats, without adverse effects on the mineral content of bone or mineralization of the organic bone matrix.6 Strontium was shown to reverse bone loss induced by estrogen deficiency in rats.7

Clinical Trials

Human clinical trials have examined the effect of strontium on bone in postmenopausal women. In the dose-ranging (Phase 2) PREVOS trial, women in early menopause were administered strontium ranelate or a placebo for two years. Strontium ranelate was given at daily doses of 125 mg, 500 mg or 1 gram. (Total weight of compound; strontium plus ranelic acid). Compared to women in the placebo group, who lost bone, women on strontium at the 1 gram dose showed statistically significant increases in bone mineral density (BMD) of the hip, thigh and lumbar spine. Biochemical markers of bone formation, such as serum alkaline phosphatase, increased. No effect on markers of bone resorption was observed, leading to the conclusion that strontium ranelate, at the 1 gram daily dose, increased bone formation without decreasing bone resorption proportionally. It was concluded that 1 gram per day is the minimum effective daily dose of strontium ranelate in these women.8

In another Phase 2 trial (STRATOS trial), 353 postmenopausal women with osteoporosis, who had experienced at least one spinal fracture, took strontium ranelate for two years at daily doses of 500 mg, 1 gram or 2 grams. Women on the 2-gram dose showed a significantly greater increase in lumbar spine BMD than those on placebo. The number of subjects who had new spinal deformities was significantly reduced.9 As in the PREVOS trial, serum levels of alkaline phosphatase, a marker of bone formation, increased, while markers of bone resorption (breakdown) decreased. The overall conclusion is that the minimum effective daily dose of strontium ranelate (whole compound) is 1 gram in early postmenopausal non-osteoporotic women and 2 grams in postmenopausal women with osteoporosis.10

Phase 3 efficacy studies on strontium ranelate have been conducted on 1649 subjects in 12 countries. These studies began with an open-run (non-controlled study period in which subjects took calcium and vitamin D supplements to normalize their blood levels of these nutrients.11 Following this, two parallel groups were administered 2 grams daily of strontium ranelate or placebo for 3-years. The subjects continued to take calcium and vitamin D during the study. In subjects on strontium ranelate, BMD increased in the lumbar vertebrae by 14.4 percent and in the thighbone by 8.3 percent. The number and risk of vertebral fractures decreased.12

Safety

Suggested Use: Take two capsules daily. Calcium intake must also be adequate. Do not take this product with calcium supplements.

Strontium ranelate was well-tolerated in the trials discussed above. The incidence of adverse events in subjects on strontium ranelate was statistically equivalent to the placebo groups, and no negative effects on hematology and other biochemical parameters have been observed.

In view of the fact that subjects on the strontium trials also took calcium, and in some cases vitamin D, to maintain normal blood levels of these nutrients, it is important to ensure calcium and vitamin D intakes are adequate when supplementing with strontium. This is underscored by earlier research on animals suggesting that increasing the intake of strontium via diet may demineralize bone when calcium is deficient.13 In rats with chronic kidney failure, strontium has been shown to cause osteomalacia, a condition in which bone is softened due to lack of mineral content. For this reason, people on kidney dialysis should not use strontium supplements.14

Scientific References

1. Shorr E, Carter AC. The usefulness of strontium as an adjuvant to calcium in the remineralization of the skeleton in man. Bull Hosp Joint Dis 1952; 13:59 -66.

2. Dahl SG, Allain P, Marie PJ, et al. Incorporation and distribution of strontium in bone. Bone 2001;28(4):446-53.

3. Baron R, Tsouderos Y. In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation. Eur J Pharmacol 2002; 450:11-17.

4. Buehler J, Chappuis P, Saffar JL, et al. Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis) Bone 2001;29(2):176-79.

5. Boivin G, Deloffre P, Perrat B, et al. Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration. J Bone Miner Res. 1996 Sep;11(9):1302-11.

6. Grynpas MD, Hamilton E, Cheung R, et al. Strontium increases vertebral bone volume in rats at a low dose that does not induce detectable mineralization defect. Bone 1996;18(3):253-9.

7. Marie PJ, Hott M, Modrowski D, et al. An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 1993;8(5):607-15.

8. Reginster JY, Deroisy R, Dougados M, et al. Prevention of early postmenopausal bone loss by strontium ranelate: the randomized, two-year, double-masked, dose ranging, placebo-controlled PREVOS trial. Osteoporosis Int 2002; 13:925-31.

9. Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis––a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab 2002;87(5):2060-66.

10. Reginster JY, Meunier PJ. Strontium ranelate phase 2 dose-ranging studies: PREVOS and STRATOS studies. Osteoporosis Int 2003; 14(Suppl 3):S56-S65.

11. Meunier PJ, Reginster JY. Design and methodology of the phase 3 trials for the clinical development of strontium ranelate in the treatment of women with postmenopausal osteoporosis. Osteoporosis Int 2003;14(Suppl 3):S66-76.

12. Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004;350(5):459-68. 13. Grynpas MD, Marie PJ. Effects of strontium on bone quality and quantity in rats. Bone 1990;11:313-19.

14. Schrooten, I, Cabrera W, Goodman WG, et al. Strontium causes osteomalacia in chronic renal failure in rats. Kidney Int 1998;54:448-56.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=697)

---

Fight Hay Fever - Help Your Sinus...

Date: July 11, 2005 09:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Hay Fever - Help Your Sinus...

HANDLING SPRING(HAY)

The National Institute of Health’s branch of Allergy and Infectious Diseases re p o rt that 40 to 50 million Americans suffer from allergies in one form or another. Many experience food allergies that a re treated somewhat diff e rently from hay fever allergies. Hay fever comes from airborne allergens, generally from pollen or pollutants.

The symptoms of allergy occur when an immune system is overactive. The immune system often recognizes something as foreign and treats it as foreign by attacking it, when in fact it really isn’t a substance the body should be concern e d with. This over-activity of the immune system leads to the release of substances including histamine that cause the symptoms of hay fever.

The most common symptoms include a runny nose and itching eyes and scratchy throat. Sometimes, an allergy will precede a sinus infection by causing swelling in the nasal membranes preventing fluids f rom exiting the sinus passages. An infection then ensues. However, most people who feel pressure over their sinuses, never develop an infection and so can be adequately treated with the supplements mentioned here. Many people experience a tickle or a shallow cough that comes from the throat rather than the lungs. They may also experience a change in emotions, becoming quite irritable or moody.

These airborne allergies can often be g rouped by season. Those people sensitive to tree pollens usually have more severe allergies in the springtime. Those sensitive to grasses are often worse in mid-summer. Those allergic to weeds have their symptoms peak in the fall. There are some unfortunate people who have allergies all summer long who may be allergic to a few plants in each group. Those who have symptoms of allerg i e s all winter long probably are allergic to molds and mildew or household animals and dust mites. On occasion, it takes a real detective to determine from where the allergies come.

There are several methods used to diagnose a cause of an allergy. In a scratch test, drops of an allergen are put on small scratches on the arm or the back. Are action is considered positive if swelling or redness occur around the scratch. A blood sample can also be used to meas ure antibody response to certain allergens. It is often helpful to determine the allergen which cause the hayfever to reduce the symptoms. There are also practitioners who use kinesiology or electronic devices to determine the cause of allergies.

The most common treatment of allergies is with antihistamines. Their side effects include drowsiness and drying of the mucous membranes of the nose and mouth. Many of the newer prescription antihistamines don’t cause drying but often have serious drug interactions and the consumer must be very careful in combining the prescription antihistamines with antifungal drugs, and blood thinning as well as asthma medication. There are some natural products that can be taken to decrease allergy symptoms. They are often equally effective without the side effects of antihistamines.

QUERCETIN

One of the more popular is quercetin. Quercetin is a bioflavonoid found in red apples, red onions, brussels sprouts, kale, peas, bell peppers, pears and asparagus. It is also found in bee pollen and propolis, two plant materials found in the beehive. It is possible to consume a fair amount of quercetin through your diet. If you have allergies, however, diet is often not enough and you may need a supplement to get enough quercetin to ontrol your symptoms. It appears quercetin decreases allergic symptoms by stopping the release of histamine. If you start taking quercetin and other nutritional supplements I will mention below before an allergy attack, they are likely to be more effective. However, don’t let that discourage you from taking them even after the symptoms have started. A common dose is 300mg to 600mg per day.

BROMELAIN

Bromelain is a nutrient often extracted f rom pineapple. Found in many digestive formulas, it is an enzyme that helps absorption. If it is found in a combination formula, chances are, it is there to help with the absorption of the other nutrients such as quercetin. Bromelain also has an anti-inflammatory effect. When someone develops allergy symptoms, part of the reason is due to the inflammatory response to substances such as histamine that are released as the allergy takes hold. This causes inflammation in the tissues which then manifests with redness and swelling.

VITAMIN C

Vitamin C is useful in many conditions including hay fever. Higher doses are often required in the treatment of allergies: 2,000mg is beneficial and you can take up to 4,000mg or more during acute symptoms. It also stabilizes capillaries, reducing the swelling in the throat, nasal passages and around the eyes. If you are taking a multi-vitamin or a combination product that contains Vitamin C, I still recommend additional supplementation.

NETTLE (URTICA DIOICA)

Stinging nettle is probably a plant many a re familiar with, especially if it has come into contact with your skin, but it also has an historical use in the treatment of allergy. In fact, in double blind studies it was shown to decrease the symptoms of allergy, specifically runny nose.

EPHEDRA (MA HUANG)

The active component of the ephedra herb is ephedrine, an alkaloid. It is used in OTC asthma medication. As a natural herb, ephedra in small doses can be v e ry useful in decreasing the symptoms of colds, asthma, cough and in this case, hay fever. It is in many Chinese and American formulas that I use and I feel v e ry comfortable using 100mg to 200mg of ephedra that contain small doses of 2.5mg to 8mg of ephedra alkaloids per day. I feel comfortable using dosages of up to 15mg of ephedra alkaloids .

FEVERFEW

Feverfew is another herb with a variety of uses. You will find it in headache formulas, in fever reducing formulas, and many hay fever formulas. Like bromelain, it has an anti-inflammatory effect and reduces the swelling that occurs during a hay fever attack.

Homeopathic formulas can also be useful to reduce hay fever. There is no re ason why the herbs I’ve mentioned cannot be combined with homeopathic formulas. You may want to take them at separate times of the day.

So, if you suffer from hay fever, don’t give up. You can use these nutrients singly or in combination. You can take a formula that contains all of them and then add to that additional vitamin C for instance, or additional nettle. It may require trial and error to find the right amounts in combination that will work for you.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=571)

---

Quercetin and Bromelain - for better health.

Date: July 04, 2005 10:28 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Quercetin and Bromelain - for better health.

Benefits

Down-regulates the Body’s Response to Environmental Challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10

Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges.

Maintains Tissue Comfort by Regulating Enzymes*

Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures.

Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13

Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16

Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of free-radicals such as hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19

Helps Maintain Normal Blood Viscosity*

Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.*

Bromelain May Enhance Quercetin Absorption

In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.

Scientific References

1. Nishino, H., et. al., “Quercetin interacts with calmodulin, a calcium regulatory protein.” Experientia 1984;40:184-5.
2. Busse, W.W., Kopp, D.E., Middleton, E., “Flavonoid modulation of human neutrophil function.” J. Allergy Clin. Immunol. 1984;73:801-9.
3. Havsteen, B,. “Flavonoids, a class of natural products of high pharmacological potency.” Biochemical Pharmacology 1983;32(7):1141-48.
4. Middleton, E., “The Flavonoids.” Trends in Pharmaceutical Sciences 1984;5:335-8.
5. Otsuka, H. et. al., “Histochemical and functional characteristics of metachromatic cells in the nasal epithelium in allergic rhinitis: Studies of nasal scrapings and their dispersed cells.” J. Allergy Clin. Immunol.1995;96:528-36.
6. Fox, C.C., et. al., “Comparison of human lung and intestinal mast cells.” J. Allergy and Clin. Immunol. 1988;81:89-94.
7. Pearce, F.L., Befus, A.D., Bienenstock, J., “Mucosal mast cells III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.” J. Allergy and Clin. Immunol. 1984;73:819-23.
8. Middleton, E. Drzewiecki, G., Krishnarao, D., “Quercetin: an inhibitor of antigen-induced human basophil histamine release.” J. of Immunology 1981;127(2):546-50.
9. Bennett, J.P., Gomperts, B.D., Wollenweber, E.,“ Inhibitory effects of natural flavonoids on secretion from mast cell and neutrophils.” Arzneim. Forsch/Drug Res. 1981;31(3):433-7.
10. Middleton, E. Drzewiecki G., “Naturally occurring flavonoids and human basophil histamine release.” Int. Archs Allergy appl. Immun. 1985;77:155-7.
11. Yoshimoto, T. et. al., “Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase.” Biochemical and Biophysical Research Communications 1983;116(2):612-18.
12. Della Loggia, R., et. al., “Anti-inflammatory activity of benzopyrones that are inhibitors of cyclo- and lipo-oxygenase.” Pharmacological Research Communications 1988; 20(Supp. V):91-94.
13. Middleton, E., Suresh, A., “Quercetin inhibits lipopolysaccharide-induced expression of endothelial cell intracellular adhesion molecule-1.” Int. Arch. Allergy Immunol. 1995;107:435-6.
14. Taussig, S.J., Batkin, S., “Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application.” An Update Journal of Ethnopharmacology 1988;22:191-203.
15. Lotz-Winter, H., “On the pharmacology of bromelain: An update with special regard to animal studies on dose-dependent effects.” Planta Medica 1990;56:249-53.
16. Taussig, S.J., “The mechanism of the physiological action of bromelain” Medical Hypothesis 1980;6:99-104.
17. Ako, H. Cheung, A.H.S., Matsuura, P.K., “Isolation of a fibrinolysis activator from commercial bromelain.” Arch. Int. Pharmacodyn. 1981;284:157-67.
18. Afanas’ev, I.B. et. al., “Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.” Biochemical Pharmacology 1989;38(11):1763-69.
19. De Whalley, C.V., “Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages.” Biochemical Pharmacology 39(11):1743-50.
20. Beretz, A. Stierle, A., Anton, R. Cazenave, J., “Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin.” Biochemical Pharmacology 1981;31(22):3597-600.
21. Heinicke, R. van der Wal, L. Yokoyama, M., “Effect of bromelain (Ananase®) on human platelet aggregation. ”Experientia 1972;28(7):844.
22. Hollma, P. et. al., “Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers.” Am. J. Clin. Nutr. 1995;62:1276-82.
23. Giller, F.B., “The effects of bromelain on levels of penicillin in the cerebrospinal fluid of rabbits.” A., J. Pharm. 1962;134:238-244.
24. Bodi, T., “The effect of oral bromelain on tissue permeability to antibiotics and pain response to bradykinin; double-blind studies on human subjects.” Clin. Med. 1965;72:61-65

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=546)

Date: June 30, 2005 09:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Echinacea - Choosing The Ideal Immune Support

Echinacea By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Echinacea, pronounced ek-i-NAY-see-a, is one herb that has become a “household” name in the 1990’s. Many refer to it as “Purple Cone Flower” because of its large purple daisy petals, which contain a hard and spiny center cone. These spines probably give the plant its name, since sea animals with spines are called “echinoderms”. Echinacea is indigenous to the U.S., and can be found both growing wild in many areas as well as in cultivated gardens. There are actually nine different species of the plant; two are most popular as remedies: Echinacea angustifolia and Echinacea purpurea. Echinacea has a long history of use by Native Americans, who have utilized the herb for a wide variety of treatments ranging from stings, poisoning, toothaches and swollen glands to colds and sore throats. It has also been touted as an ideal natural remedy for snake bites. In particular, the benefit of Echinacea as a treatment for snake bites brought national attention to the herb in the last half of the 1800’s. Dr. H.F.C. Meyer of Pawnee City, Nebraska first tried to interest Eclectic Physicians (doctors who used natural medicines) to use Echinacea as an herbal remedy for snake bites by volunteering to be bitten by a rattlesnake to prove its effectiveness. Although his dramatic offer was rejected, his enthusiasm and concerted efforts led to renewed interest and investigative studies on Echinacea, resulting in the herb’s emergence as one of the most popular natural plant therapies by the turn of the century.

Extensive studies on Echinacea’s medicinal properties continue to mirror the earlier usages of the herb as experienced by indigenous people. In fact, Echinacea is part of the official materia medica listed in the German Commission E. Monographs, a universally recognized publication reputed to be the official information authority on herbal medicines. The Commission lists a number of medicinal applications for Echinacea as an ideal treatment for such conditions as colds, chronic infections of the respiratory tract and lower urinary tract ailments, as well as topically for chronic ulcerations and slow healing wounds.

Echinacea has been shown to be a potent immune system stimulant. Nature’s Answer® offers an outstanding Echinacea fluid herbal extract formula in a unique blend that contains both Echinacea angustifolia root and Echinacea purpurea whole plant. Fluid extracts that feature both whole plant and root parts in the formula insure that the highest levels of the whole herb’s active constituents are maintained. A further advantage to this kind of supplement lies in its delivery system– liquids are faster to absorb and easier to assimilate by the body than tablets or capsules. Nature’s Answer®’s Echinacea formulas are available in either alcohol-free or organic alcohol forms. In addition, the alcohol-free supplements are also offered in a tasty grape or tangy orange flavor.

Two popular blends featuring Echinacea with other supportive herbs are Immune Boost™ and Re-Zist™. Immune Boost™ combines Echinacea with Wild Indigo and Maitake Mushroom. Re-Zist™ contains Echinacea, Goldenseal, Wild Indigo, Cayenne and Myrrh for potent support.

Echinacea is also recognized for its ability to enhance the resistance of cells to viruses, especially when used after cells have been exposed to colds and flus. As a preventative, formulas such as Nature’s Answer®’s Echinacea/Goldenseal (alcohol-free, organic alcohol) are ideal. This is an excellent supplement for soothing sore throats and helping to shrink swollen glands. An added benefit to the formula is the presence to berberine, the active ingredient in Goldenseal, which provides further wellness enhancement.

Many studies have focused on Echinacea’s possible use for ailments such as psoriasis and early rheumatoid arthritis. The herb also acts as an overall anti-inflammatory tonic. Nature’s Answer®’s Blood Support™ (alcohol-free) combines Echinacea with Dandelion, Licorice and other herbs for an anti-inflammatory effect. Allertone™ (alcohol-free) blends Echinacea with Mullein Leaf to help support the respiratory and sinus areas.

Most herbal practitioners suggest using Echinacea for short-term periods. There has been evidence to suggest that the herb loses its effectiveness when used over longer periods of time. Also, in the case of autoimmune illnesses, some people believe Echinacea may OVER-stimulate the immune system, although there is no solid research to back this contention. Echinacea is probably most effective if used in frequent doses for 5-7 days at the early onset of symptoms. It may also serve as a preventative during periods after known exposure or during extra stress, taking it two to three times a day every other or every third day. The German Commission E lists no known drug interactions or side effects with Echinacea. It is indeed one of the safest and most effective herbs for natural immune support today.

Echinacea seems well suited to life in the 90’s with all the stresses upon our immune systems. Its importance and effectiveness as an immune stimulant is as true today as it was in 1927 when Dr. Liebstein stated:

“Nature has probably destined Echinacea to be used for remedial purposes only, as a sustainer of vitality, an organizer of the defensive powers of the system, to such an extent as to be justly crowned the greatest immunizing agent in the entire vegetable kingdom....” written in 1927 by Dr. A. M. Liebstein (Foster, 1991)

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=539)

---

REFERENCES

Date: June 25, 2005 08:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: REFERENCES

REFERENCES

1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=507)

---

Herbal Forms

Date: June 25, 2005 10:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbal Forms

Herbal Forms

Extract: An extract made from ginkgo leaves is available in Europe and is used for cerebral arteriosclerosis in peripheral circulatory disorders of the elderly.

Tincture: Ginkgo tincture is often combined with other herbs such as periwinkle and used for circulatory problems and venous disorders.

Infusion: Infusions of ginkgo are used for arteriosclerosis, varicose veins and hemorrhoids.

Capsules: Powd e red forms of ginkgo can be used to enhance brain function and memory.

Storage: Keep in a dark container in a cool, dry environment.

Regulatory Stauts:
U.S.: none
U.K.: none
Canada: none
France: over-the-counter drug status
Germany: over-the counter drug status

Recommended Usage: Ginkgo should be taken in normal dosages and, if possible, at the same times eve ry day. In the case of ginkgo, taking it consistently for 12 weeks is recommended. Although injections of Gingko have sometimes been used, oral ingestion of a tablet or capsule is therapeutically effective. More advanced p reparations of ginkgo make it possible to obtain higher concentrations of flavoglycosides in smaller amounts of extract.

Safety: Ginkgo extracted from the leaves of the ginkgo tree is considered nontoxic and is virtually without side-effects. It can be safely used with other supplements without interaction and has no reported toxicity. In rare cases, some gastric upset or incidence of headache or skin rash have occurred, which may indicate that the individual is allergic to the substance. The fruit pulp of ginkgo can produce seve re contact dermatitis and other allergic reactions. The leaf extract of ginkgo is usually the only form that is available and is extremely safe.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=446)

---

RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available

Date: June 24, 2005 05:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available

The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.

Bio-Aligned Antioxidant Support

RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.

Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.

Healthy Heart

Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.

Nourishing the Brain

Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.

Liver Support

Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.

Immune Defense

The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.

Skin & Connective Tissue

Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.

Clear Vision

Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.

Energy Generation

Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.

DNA Protection

DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.

Living Longer, Living Better Strategies for Wellness

• Stop Smoking: Smoking depletes the body of vitamins C and E along with other antioxidants.

Wellness Revolution

Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.

References

Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.

Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf

Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein

Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts

Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric

Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE

Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc

Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=422)

---

VANADIUM W/CHROMIUM - Supports Healthy Blood Sugar Levels

Date: June 24, 2005 05:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: VANADIUM W/CHROMIUM - Supports Healthy Blood Sugar Levels

Today’s sedentary lifestyles and sugar-rich, nutrient-poor foods are contributing to the rise of obesity in our society. The result: challenges to your body’s system of balancing blood sugar levels and insulin activity. Maintaining a healthy diet and lifestyle helps keep blood sugar levels in the normal range, but sometimes you need nutritional support when you don’t have time to make those healthy food choices. Source Naturals, the science company, introduces VANADIUMW/CHROMIUM for blood sugar support. Research shows that these two important minerals help maintain normal blood sugar levels when used as part of your diet.

Vanadium works together with chromium to support healthy blood sugar levels. Research has shown that both of these important minerals play a key role in normal insulin function.

Vanadium: Balances Insulin Activity Vanadium, named after Vanadis the Norse goddess of beauty, belongs to a group of biologically important metals known as transition elements. These metals have a natural tendency to form complexes with organic compounds called coordination compounds that serve important biological functions.

Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. The sugar that remains in the blood can create problems by binding with protein molecules, resulting in damaged, non-functioning structures, in a process called glycation. Some evidence suggests that vanadium supports these vital metabolic processes because of its ability to mimic the actions of insulin.

More Absorbable Form of Vanadium

Absorption of dietary vanadium and supplemental vanadium is poor. It is estimated that less than 5% of dietary vanadium is absorbed. Organic forms of vanadium, such as bis-glycinato oxovanadium or BGOV, are recognized as being more absorbable. BGOV is an organically bound, bioavailable form of vanadium complexed with the amino acid glycine. Glycine, an amino acid found in the protein of all life forms, generates superior vanadium absorption.

Chromium: Supports Glucose Metabolism Chromium is a trace element the body needs in very small amounts, but it plays a significant role in human nutrition. Its most important function is to help regulate the amount of glucose in the blood. Insulin plays a role in this process, by regulating the movement of glucose out of the blood and into the cells. Chromium is a key constituent of the compound known as glucose tolerance factor (GTF). This mineral enhances the effectiveness of insulin, encouraging glucose to enter cells, where it can be burned for fuel.

Chromium participates in glucose metabolism by enhancing the effects of insulin. Insulin binds to insulin receptors on the surface of cells, activating those receptors and stimulating glucose uptake by cells. Through its interaction with insulin receptors, insulin provides cells with glucose for energy and prevents blood glucose levels from becoming elevated. Glucose buildup in the bloodstream is associated with adverse changes in lipid profiles and increased challenges for cardiovascular health. Some studies examining the effects of chromium supplementation on lipid profiles have observed reduction in serum total cholesterol, LDL cholesterol, and triglyceride levels. Source Naturals VANADIUM W/CHROMIUM includes ChromeMate®, a patented compound of chromium and niacin with proven GTF activity.

Wellness Nutrition

Taking responsibility for your health is at the heart of the wellness revolution. Sometimes life may seem like it’s passing you by and you may not have time to focus on staying healthy. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you products like VANADIUM W/CHROMIUM to help you maintain a healthy balance.

References:

Anderson, R.1998. Chromium, glucose intolerance and diabetes. Journal of the American College of Nutrition 17(6):548-555. Jellin, J., et al. 2004. Vanadium Monograph. Pharmacists Letter/Prescribers Letter Natural Medicines Comprehensive Database. Therapeutic Research Facility. Nandhini, S., et al. 1993. Insulin-like effects of bis-glycinato oxovanadium complex on experimental diabetic rats. Indian Journal of Biochemistry and Biophysics 30:73-76.

--
Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=420)

---

GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....

Date: June 21, 2005 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....

GPC (GlyceroPhosphoCholine): Versatile Life Support Nutrient

Parris Kidd, Ph.D.

GPC or GlyceroPhosphoCholine (pronounced gli-sero-fos-fo-ko-lean) is a nutrient with many different roles in human health. It reaches extremely high concentrations within our cells, and its abundance in mother's milk suggests it is crucial to life processes. Clinically, GPC has been most intensively researched for its brain benefits. Biologically, it has great importance for the skeletal "voluntary" muscles, the autonomic nervous system, kidneys, liver, and reproductive organs. GPC goes beyond being a brain nutrient; it is a nutrient for vitality and long life.

Marked Benefits to the Brain

As a dietary supplement, GPC's brain benefits are unique. It boosts mental performance in healthy young people, as shown by three double-blind trials. In trials on middle aged subjects, GPC improved several physiologic measures of mental performance: reaction time, visual evoked potential, and EEG delta slow waves. In the elderly, GPC improves mental performance and provides noticeable revitalisation. In 11 human trials with 1,799 patients, memory, attention, and other cognitive measures improved. So did mood (including irritability and emotional lability), and patients often developed renewed interest in relatives and friends. GPC was well tolerated, and generated no bad drug interactions. A large trial on elderly subjects with memory challenges published in 2003 concluded GPC had significant benefits for these individuals.

GPC Supports Normal Brain Function

Circulatory deprivation or surgery can challenge healthy brain function. GPC can speed recovery and support improved quality of life. In four trials with GPC on 2,804 subjects who experienced difficulties under these circumstances, up to 95% showed good or excellent improvement. GPC consistently improved space-time orientation, degree of consciousness, language, motor capacity, and overall quality of life. The investigators concluded GPC offered marked benefits, with an excellent benefit-to-risk profile. Up to half of patients who survive bypass surgery experience problems with memory and other mental performance. A double-blind trial conducted with bypass survivors for six months determined that the GPC group had no remaining memory deterioration, while the placebo group failed to improve.

GPC Works Through Multiple Mechanisms

GPC supports human health through a variety of mechanisms:

1. It helps keep choline and acetylcholine available to the tissues. Choline is an essential nutrient and GPC appears to be the body's main choline reservoir. GPC in mother's milk represents the baby's main source of dietary choline. Acetylcholine (ACh) is an important substance employed extensively throughout the body. ACh is a major brain transmitter; the motor nerves use ACh to drive the skeletal ("voluntary") muscles; the autonomic nervous system uses it to pace all the organs. ACh is also central to mental and physical endurance, and mind-body coordination.

2. GPC is a major cell-level protectant, not as another antioxidant but in pivotal roles of osmotic pressure regulator and metabolic antitoxin. GPC for osmotic regulation can reach very high concentrations in the kidney, bladder, liver, brain, and other organs. As metabolic protectant, GPC shields proteins against urea buildup.

3. GPC is a major reservoir for cell membrane omega-3 phospholipids. These substances are the major building blocks for cell membranes. Enzymes couple GPC with the omega-3 fatty acid DHA, to make the phospholipid PC-DHA. This makes membranes especially fluid, enabling membrane proteins to perform with better efficiency. GPC produces PC-DHA in the skeletal muscles, wherein fluidity is essential for contraction. Muscles that function abnormally can show GPC deficiency.

4. GPC contributes to both male and female in reproduction. As spermatozoa mature, GPC is used to make PC-DHA that makes their membranes fluid to enable motility. With men, the lower their semen GPC the greater the likelihood of poor sperm motility and with it, infertility. Once semen is inserted into the female, an enzyme in uterine secretions breaks down the semen's GPC into substances that energize the sperm to achieve fertilization.

Dosing, Safety, Tolerability, Compatibility

Oral intake of GPC in the clinical trials was usually 1,200 milligrams (mg) per day, taken early in the day on an empty stomach. A reasonable dietary supplementation regimen is 1200 mg/day, taken in divided doses (AM and PM) between meals for 15-30 days, and thereafter 600 mg/day for maintenance. Symptomatic subjects can take 1200 mg/day until adequate improvement is achieved. Young, healthy subjects may experience benefit from daily intakes as low as 300 milligrams. GPC is very safe, being compatible with vitamins and nutrients and with pharmaceuticals. In clinical trial comparisons, GPC's benefits surpassed the nutrients acetylcarnitine and CDP-choline.

GPC: Nutrient for All Ages

GPC is unmatched for its support of active living and healthy aging. In some 23 clinical trials GPC improved mental performance in all functional categories. GPC can revitalize the aging brain, facilitating growth hormone (GH) release and boosting nerve growth factor actions. GPC's ample presence in human mother's milk suggests it could be conditionally essential. By supporting mental integrity, mind-body integration, the autonomic system, and the body's other organs, GPC enhances the active lifestyle. GPC is remarkable nutritional support for optimal health at any age.

Parris M. Kidd, PhD is a cell biologist trained at the University of California, Berkeley and San Francisco. Since entering the dietary supplement field in 1983, he has published many in-depth reviews of integrative medicine in the journal Alternative Medicine Reviews, and is science columnist for totalhealth magazine. Dr. Kidd is internationally recognized for his accomplishments in dietary supplement product development, documentation and quality control.

Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=388)

Date: June 21, 2005 05:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Keto - The Key to Healthy Aging

7-Keto " The Key to Healthy Aging

The global population is aging at an alarming rate and causing an explosion in health care costs, insurance premiums, cosmetic surgery and more. In the U.S. alone, more than one million baby boomers are expected to live to 100 years of age or older. This increased life expectancy presents a whole new set of health concerns that the medical community has not had time to address, since there is a greater need to care for age-related health problems in this ever-growing elderly population.1

Aging and the Decline in Vital Nutrients

We all grow old at the same rate but people age at different rates. Aging is a process of gradual changes that occur to varying degrees in each of us. Interestingly, the aging process is composed of different components and interactions, some of which can be impacted. One such component is the declining level of essential biological compounds, which causes our bodily functions to slow and become dysfunctional. Our organs don?t work efficiently, our immune system becomes lazy, we lack energy, our metabolism drops and we gain weight easily.1 7-oxo DHEA (7-Keto™) is a naturally occurring compound that declines with age.2 Replacing this key metabolite helps promote a healthy immune system and maintains resting metabolic rate at levels that accelerate weight loss during standard weight reduction programs.

Aging and a Healthy Immune System

Numerous changes occur in the immune system with advancing age, probably contributing to decreased immune responsiveness. Although all segments of the immune system are affected, investigators have most consistently identified declines in cellular or T-cell mediated immune function in the elderly. The decline in T-cell immune function is generally associated with an increased susceptibility to foreign organisms. For example, individuals with age-related declines in cellular immunity have an impaired response to vaccinations, making them more susceptible to health imbalances even though they have had their shots. In a clinical study presented at the Federation of American Societies for Experimental Biology meeting in April 2004, the effect of 7-Keto on elderly immune function was evaluated. Healthy elderly adults were given 7-Keto orally twice daily over a period of one month. The study revealed that 7-Keto augmented several key T-cell mediated immune function parameters compared to placebo administration.4

Age-Related Weight Gain

Age-related weight gain and obesity are approaching epidemic proportions in our country.5 Weight gain is a disorder of energy balance involving energy intake and/or expenditure. Low energy expenditure, a drop in resting metabolic rate (RMR), is a challenge during most weight loss attempts due to age, calorie restriction, lack of physical activity or a combination of factors. RMR represents 60% of total daily energy expenditure. Maintaining a higher RMR as we age and during weight reduction programs helps us achieve and maintain a normal weight. Furthermore, compounds with the thermogenic potential to achieve even minimal increases in daily energy expenditure of 2-3% may have clinical relevance in preventing the decline in RMR with calorie restricted diets or weight loss, and in decreasing the risk of regaining weight. 7-Keto, a non-stimulant thermogenic compound, has been shown to significantly increase energy expenditure in humans.6 A recently completed clinical study, also presented at the Federation of American Societies for Experimental Biology 2004 meeting, revealed that administration of 7-Keto to overweight adults in conjunction with a calorie restricted diet effectively reversed the decline in RMR normally associated with dieting. Obese participants following a calorie-restricted diet demonstrated a 5.4% increase in daily RMR with 7-Keto.7 The magnitude of the increase in RMR by 7-Keto is clinically relevant, and represents a promising agent for enhancing thermogenesis and weight loss in obese individuals on calorie-restricted diets. Additionally, 7-Keto has been shown in two confirmatory published clinical studies to result in three times more weight loss compared to diet and exercise alone. It has a favorable side effect profile and is easy and convenient to take.8,9 Our life expectancies will likely be longer than those of our parents, and our quality of life during those years will depend on how well we take care of our bodies now. Undoubtedly, the science of aging will give rise to new and exciting technologies to help us age more gracefully and healthfully. Maintenance of healthy immune function is keenly needed for improved quality of life in the elderly. Dietary manipulation and supplementation has been identified as a method of immune system renewal, and supplements such as 7-Keto may play an important future role as immune system modulators. Moreover, the addition of 7-Keto to any weight loss program will offer vital support of energy expenditure and help with the attainment of a manageable and healthy weight into our older years.

References

1. 1995 White House Conference on Aging, ?Executive Summary: The Road to an Aging Policy for the 21st Century," February 1996: 17-18. 2. Marenich LP. Secretion of Testosterone, Epitestosterone, Androstenedione, and 7-Keto-Dehydroepiandrosterone in Healthy Men of Different Ages. Prob Endokrinol. 1979; 25(4): 28-31. 3. Ginaldi L, De Martinis M, D?Ostilio A, Marini L, Loreto MF, Quaglino D. Immunological Changes in the Elderly. Aging 1999; 11(5): 281-286. 4. Zenk JL, Kuskowski MA. The Use of 3-acetyl-7-oxo-dehydroepiandrosterone for Augmenting Immune Response in the Elderly, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 5. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and Trends in Obesity Among US Adults. 1999-2000. JAMA 2002;288:1723-1727. 6. Astrup A. Thermogenic Drugs as a Strategy for Treatment of Obesity. Endocrine 2000;13(2):207-212. 7. Zenk JL, Leikam SA, Kassen LJ, Kuskowski MA. A Prospective, Randomized, Double Blind Study to Evaluate the Effect of HUM5007 and 7-oxo DHEA on Resting Metabolic Rate in Overweight Adult Men and Women on a Calorie Restricted Diet, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 8. Kalman DS, Colker CM, Swain MA, Torina GC, Shi Q. A Randomized, Double-Blind, Placebo Controlled Study of 3-Acetyl-7-Oxo-Dehydroepiandrosterone in Healthy Overweight Adults. Current Therapeutic Research 2000;61: 435-442. 9. Zenk JL, Helmer TR, Kassen LJ, Kuslowski MA. The Effect of 7-Keto Naturalean on Weight Loss: A Randomized, Double-Blind, Placebo-Controlled Trial. Current Therapeutic Research 2002; 63:263-272.

John L. Zenk, M.D., is Chief Medical and Scientific Officer for Humanetics Corporation and President and Medical Director of Minnesota Applied Research Center, both located in Eden Prairie, MN. He has spoken nationally and internationally on the subjects of integrating conventional and complementary medicine, anti-aging technologies, evaluating the effectiveness of alternative medicine, and dietary supplement research and development. He is author of the book Living Longer in the Boomer Age, and co-author of the book Age Wise and is a frequent contributor to national media. He has served as Principal Investigator for 15 controlled clinical studies, three of which were recently published in national peer-reviewed journals, and has presented abstracts at the 11th World Congress for Food Science and Technology and the Federation of American Societies for Experimental Biology.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=383)