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Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?
Date:
December 07, 2023 12:12 PM
Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body. While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption. GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age. The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels. In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body. This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form. But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them. So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing! Liver HealthWhen it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ. Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds. During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances? But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker! The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning. So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being! Alcohol IntoxicationAlcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells. To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes. The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group. The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver. Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels. Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-Scale clinical trials is necessary to validate its efficacy. In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management. Beautiful SkinBy activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions. Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores. Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects. Skin LighteningSkin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract. The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women. In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH. Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin. The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities. In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592) Omega-3s found to benefit children diagnosed with behavioraldisorders
Date:
April 26, 2019 03:15 PM
It is common knowledge that omega-3s can promote heart health, but now studies are showing that they can also help children who are suffering from behavioral disorders. A study was published within the Journal of Dietary Supplements that showed kids aged six to twelve showed great improvement in regards to their overall health status and quality of life when they were given doses of omega-3s on a regular basis. The study evaluated exactly 942 children, so the findings are quite consistent. Key Takeaways:
"To evaluate the effectiveness of omega-3 fatty acid supplementation, the researchers used the Kidscreen-10 and the Strengths and Difficulties Questionnaires (SDQ). The SDQ examines 25 positive and negative attributes, which are divided among five scales: emotional symptoms, conduct problems, hyperactivity or inattention, peer relationship problems, and prosocial behavior." Read more: https://www.naturalnews.com/2019-03-17-omega-3-benefits-children-with-behavioral-disorders.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6196) 5 powerful reasons to start eating garlic TODAY
Date:
April 23, 2019 02:41 PM
Garlic is an essential ingredient in many kitchens, and also demonstrates an impressive array of health benefits. For example, garlic can encourage higher production of hydrogen sulfide, which helps to keep your blood vessels open and supple, reducing your risk of heart disease. Garlic can help mitigate metabolic syndrome and reduce your risk of several types of cancer, including stomach cancer. By neutralizing enzymes that help break down bone, garlic may also help to ward off osteoarthritis, too. Key Takeaways:
"Garlic, a member of the onion family, has a centuries-long history of medicinal use on a global scale." Read more: https://www.naturalhealth365.com/garlic-heart-disease-2766.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6162) Can Gut Bacteria Affect Your Mental Health?
Date:
April 02, 2019 02:06 PM
There are two different microbes called Coprococcus and Dialister that are now showing a correlation between depression and the absence of these two floras. A study was done in which 1,000 participants filled out assessments that analyzed their quality of life. Those who were shown to have significant signs of depression were more likely to have a deficiency in the two previously mentioned forms of gut flora. Since the microbes in our gut are responsible for other conditions such as childhood Leukemia and inflammatory diseases, their correlation to mental wellness is not a complete shock. Key Takeaways:
"Researchers from Belgium recruited more than 1,000 people in order to examine their gut microbiome. Of them, 173 participants were diagnosed with depression or fared poorly in a survey assessing their quality of life." Read more: https://www.medicaldaily.com/can-gut-bacteria-affect-your-mental-health-429678
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6111) Can CBD oil help with pain, and can raisins really help you sleep?
Date:
March 09, 2019 09:44 AM
1.There is scientific support for the use of cannabis-based medicines to manage chronic pain. However, medicinal marijuana is not availabe in all states. Where it is not available, some are using CBD oil as an alternative. CBD is cannabidiol, a compound derived from cannabis. 2.Hot compresses are sometimes prescribed to treat a condition called blepharitis, which affects the eyelids. It can be difficult to keep a hot compress hot for more than a short time. Hand warmers and reheatable Dry Eye Relief Masks are a good alternative. 3.Eating a handful of raisins before bedtime can reduce the number of bathroom trips during the night. Key Takeaways:
"I live in an upscale retirement community, and a large number of people here are using marijuana oil to relieve pain without side effects." Read more: https://www.seattletimes.com/life/wellness/pharmacy-marijuana-senior-citizens/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6071) Higher omega-3s status linked to less depression in population withheart failure
Date:
September 20, 2018 05:11 PM
A recent American College of Cardiology study of 108 chronic heart failure patients noted that patients with higher omega-3 index levels as a result of oral supplementation appear to suffer less from depression than the control group. Roughly 20 percent of chronic heart failure patients become clinically depressed. The promising results suggest that increased omega-3 index levels may result in better social functioning and reduced cognitive symptoms of depression as measured by the widely-used Hamilton Depression Scale. More research is needed, however, to better understand the impact of omega-3 indexes on depression. Key Takeaways:
"A recent pilot study has linked a higher Omega 3 Index with lessened symptoms of depression in a cohort of subjects suffering from chronic heart failure." Read more: https://www.nutraingredients-usa.com/Article/2018/08/22/Higher-omega-3s-status-linked-to-less-depression-in-population-with-heart-failure
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5769) Psoriasis: 7 Tried And Tested Natural Remedies
Date:
May 22, 2018 09:16 AM
Psoriasis is a condition in which red, scaly patches of skin appear on the skin's surface. The symptoms of psoriasis can appear in anyone, but those who smoke or are obese and have other related conditions are more prone to developing the skin condition. There are many natural remedies that can reduce the appearance and irritating symptoms that go along with psoriasis such as salt baths, apple cider vinegar, and even aloe vera. While there is no official cure for psoriasis, these remedies can at least help ease the symptoms. Key Takeaways:
"Here's a list of the tried and tested natural remedies for treating psoriasis." Read more: https://doctor.ndtv.com/skin/psoriasis-7-tried-and-tested-natural-remedies-1841466
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5600) Top Nutrient-Dense Foods & Their Benefits
Date:
August 12, 2017 07:14 AM
Nutrient dense foods provide high nutrients with a low calorie intake. Some nutritionists are pushing the idea that we need to eat foods that are nutritionally dense. They claim this is healthier than just fewer calories and making up for lost nutrition with supplements. They have gone as far as to give foods a density score, a scale with which they rank foods nutritional value by servings. Also mentioned is how modern farming techniques are making foods once thought to be "super foods" less nutritionally dense. Finally, some practical advice on what foods should be consumed is given. Read more: Top Nutrient-Dense Foods & Their Benefits
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5112) Oolong Tea Benefits the Brain, Heart, Skin & More
Date:
May 14, 2017 11:44 AM
In the article “Oolong Tea Benefits the Brain, Heart, Skin & More” It shows that there are many benefits for using Oolong Tea, which is made in China. Some benefits are that can prevent cancer, it can decrease causes for heart diseases. They can also reduce your chances of being obese, of getting diabetes, and in both inflammation and oxidative stress. You will also have a raise in cognitive function, and healthy organs like healthy skin, and healthy bones. Key Takeaways:
"On a large scale, the consumption of oolong tea is associated with a decreased risk of death from heart disease" Read more: https://draxe.com/oolong-tea-benefits/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4614) Anti-inflammatory Cannabis Compound Useful in Itching, Other Skin Treatment
Date:
April 23, 2017 06:44 PM
A recent study by the American Academy of Dermatology has show that the use of a cannabinoid for three weeks can eliminate severely itchy skin. The key ingredient is the chemical component THC or tetrahydrocannabinol which has anti-inflammatory properties. The importance of this study suggests that a topical ointment consisting of cannabinoids can reduce or eliminate several skin conditions which have proven hard to treat with typical ointments. These conditions include eczema and psoriasis. One caveat however, this study has only been based on a small sampling of participants and no large scale studies have been performed as of yet. Read more: Anti-inflammatory Cannabis Compound Useful in Itching, Other Skin Treatment
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4464) In praise of turmeric, the magic yellow spice.
Date:
March 23, 2017 02:44 PM
For those who pursue optimum health, Turmeric is a spice that should not be overlooked. Turmeric boasts a myriad of wonderful health benefits including it's anti-inflammatory and anti-cancer properties. Turmeric can be added to a great many meals and can also easily be added to smoothies if you want to find ways to incorporate it into your diet. Read on to find out more creative uses of turmeric, and how to make it more easily absorbed in the body. Key Takeaways:
"The magic is in the Curcumin which is the potent compound within turmeric." Read more: https://www.lorrainepascale.com/in-praise-of-turmeric-the-magic-yellow-spice/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4272) B vitamins may have 'protective effect' against air pollution
Date:
March 15, 2017 06:44 AM
The article discusses a recent study which suggests that high dosage of vitamin B may provide protection against the negatives of air pollution. This study was done on a small scale, and there are plans to attempt to replicate this affect in larger cities with more air pollution.A large portion of the population lives in a city with significant environmental pollution. If this study is proven true on a larger and more significant scale it may be lead to a decrease in the health affects from pollution in major cities Read more: B vitamins may have 'protective effect' against air pollution
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4154) Is the water you're drinking linked to causing heart attacks and cancer?
Date:
February 28, 2017 12:59 PM
Water chlorination has been the cheapest method of disinfection for over a century. Chlorine efficiently disinfects large quantities of water. It is generally used to prevent outbreaks such as salmonella, and can even inactivate the human norovirus. For these reasons, the EPA classifies chlorine as a pesticide. Even though chlorine is an effective pesticide, on a grand Scale, it is hard to measure how quickly microorganisms learn to evolve and resist the persistent use of this chemical. Could widespread dependence on chlorine contribute to accelerated microbial resistance? Key Takeaways:
"Could widespread dependence on chlorine contribute to accelerated microbial resistance?" Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4044) Is Pineapple Acidic and Can Pineapple Cause Acid Reflux?
Date:
February 27, 2017 10:59 AM
If you suffer from acid reflux, you probably go out of your way to avoid overly acidic foods. However, there is much debate on where pineapple lands on the pH spectrum. Pineapple is indeed acidic, but it also contains bromelain, which has been known to fend off acid reflux. It may still cause acid reflux in those more sensitive to acids, but pineapple usually has an alkalizing effect on stomach acids. If you are willing to give it a try, pineapple has some great health benefits that include a low calorie count and moderate levels of essential vitamins and minerals. Key Takeaways:
"But for those unaffected by acid reflux, pineapple is an excellent source of vitamins and minerals to keep the body running smoothly." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4034) Greatist: Your Ideal Weight Isn't What You Think
Date:
February 18, 2017 02:59 PM
Many people have attempted dieting with a goal weight in mind, But is physical and mental health a factor in this. Science is unable to tell you what you should weigh they can only give you a generalization with body mass index. What really matters is that your are taking in enough calories and exercising a healthy amount. This along with good sleeping habits can keep you from going hopping on and off the Scale often. Key Takeaways:
"Your BMI tells you almost nothing about your nutritional status, body fat percentage, or strength, and therefore tells you almost nothing about how healthy you are (or aren’t)." Reference: //www.huffingtonpost.com/Greatist/your-ideal-weight-isnt-wh_b_12851632.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3970) Low levels of manganese in welding fumes cause neurological problems
Date:
January 10, 2017 10:59 AM
Recently a new study has found that welders that are exposed to airborne manganese at some estimated levels that are under safety standards set by federal law have developed neurological problems. In general the current standards that are set for safety might not be adequate enough to protect welders from the dangers that come with it. Key Takeaways:
""We found that chronic exposure to manganese-containing welding fumes is associated with progressive neurological symptoms such as slow movement and difficulty speaking," said Brad A. Racette, MD, a professor of neurology and the study's senior author." Reference: https://www.sciencedaily.com/releases/2016/12/161228171126.htm
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3764) Development of castor oil.
Date:
January 03, 2017 09:46 PM
There are about hundreds of castor oil factories in China, of which only about 10% castor oil manufacturers start working; large processing plants have around 20; only nine plants have tens of thousands processing capacity. About 70% of Chinese castor oil processing factories in stop production or semi-shutdown state, because there are no adequate, high-quality raw material castor sources. At the end of the 1980s, China extends and built several large Scale castor oil factories, each factory's total amount of annual output of castor oil are in 10 -15 thousand tons, total production capacity is about 55,000 tons per year. The world's major markets of castor oil were concentrated in North America and Europe, of which the France, Britain, Netherlands, United States, Germany, five countries accounted for 61% of annual fuel consumption. India castor oil used in making soap has about 1.6-1.8 million tons, the textile industry uses 2-3 thousand tons, chemical industries use 2-3 thousand tons, lubricating oil use 5-6 thousand tons, the rest for exporting. In Japan's castor oil use amount, paints accounted for 28.6%, the surfactant is 12.3%, cosmetic raw material is 8.2%, resin is 5.7%, hardened oil is 17.8%, sebum oil is 12.9%, others is 14.5%. Japan needs to import large quantities of castor beans every year; they are mostly imported from China, Pakistan, Indonesia, Sri Lanka, Philippines, Vietnam, Ethiopia, Brazil and other countries. Castor oil in the United States for the production of plastics and resins was accounted for 25.9%, fatty acids accounted for 12.7%, lubricating oil accounted for 6.3%, paint accounted for 23.7%, cosmetics (mainly synthetic waxes) accounted for 2.1%, others such as inks, surfactants accounted for 29.1%, these castor oils are imported from foreign countries. Every year, the world needs 700 thousand tons of castor oil, convert into 1.6 million tons castor beans. Nowadays, gasoline resource was gradually reduced, transportation, live used gasoline was rapidly increasing, use gasoline as a raw material for synthetic material will be increasingly constrained in cost. And the United States study found that long-term exposure to polymers which synthesized by gasoline was harmful to human health. California and some other states have enacted laws and regulations for this, to restrict and gradually prohibit using synthetic resin in city buildings, interior facilities and human health-related sites and articles, which is polymerized from petroleum, natural gas cleaved into monomers raw materials, it makes castor oil's demand was rising sharply. Castor cultivation in China is very commonly; there is no open planted regional division. South from Hainan Island, north to Heilongjiang is cultivated. Because castor hybrids with drought resistance, thin ridge resistant, saline-alkaline tolerance, well-adapted, simple to manage, less invest, high efficiency and other salient features, no matter grain field or hills, rocky land, saline-alkali soil and even around the house can be grown it. So anywhere in China can be planted castor. Related Products
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3738) Calcium Supplements and the Heart: Clearing Up the Confusion
Date:
November 26, 2016 12:59 PM
The Institute of Medicine has recommended 1000-1200 mg of calcium daily for most adults, and the tolerable upper intake level has been set at 2000-2500 mg of calcium daily. Even a recent observational study from the MESA cohort suggested an association between calcium supplements and coronary artery calcium, but it is important to note that in observational studies, the association does not prove causation. In the large-Scale Women's Health Initiative calcium and vitamin D trial, we found no association between calcium and vitamin D supplementation and coronary artery calcium measured at the end of the 7-year trial. Key Takeaways:
"We know that both calcium and vitamin D are essential for bone health, but concerns have been raised from selected reports in recent years about heart risk." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3513) How Much Should You Push Yourself with Depression?
Date:
November 23, 2016 12:59 PM
Depression is a reality that affects all too many. One of the toughest decisions is knowing when to push and when to cut yourself some slack. The key to making this decision above all is to know yourself. Find out what it is about yourself that can help you identify your triggers for stress and learn to combat them with the perspective and experience of Therese J. Borchard. Key Takeaways:
"Do you typically push yourself too much or do you need to be pushed? That will help you know what to do when you get depressed. If you constantly beat yourself up for not doing everything perfectly in recovery, or in life, maybe you should throttle back to part-time (if you can afford it) and try to allow yourself to heal. If you typically need other people to inspire you to change, then maybe pushing yourself is the right thing to do." Reference: //psychcentral.com/blog/archives/2016/11/05/how-much-should-you-push-yourself-with-depression/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3495) These are the biggest mistakes people make when trying to eat healthy
Date:
November 15, 2016 07:04 AM
There are some common pitfalls to avoid when you decide to start eating healthier. Just because something is labeled “healthy” doesn’t make it so. Check your labels and know your ingredients and then be sure to keep your portions under control as well. You still need to count your calories when you are eating healthy so you know if you are eating too much or too little, as both are common problems. Key Takeaways:
"Ignoring moderation because "it's healthy!" - so you're eating fresh, whole foods." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3446) Curcumin Helps Alleviate Depression
Date:
October 26, 2016 08:24 PM
Curcumin is a phenolic acid that can be sourced from the cooking spice turmeric. It acts as a powerful antioxidant in humans and protects the body's cells from dangerous free radicals (harmful by-products that are released into the cells during oxygen related reactions). Provisional studies suggest that it may also have many more health benefits. There is also some evidence that curcumin or turmeric may help alleviate the symptoms of certain skin diseases, viral infections, diabetes, colitis, stomach ulcers, and high cholesterol. Once again, the ancient herbal remedy is being celebrated as a modern wonder drug. But perhaps the most promising results have been seen in the use of curcumin to treat depression. Curcumin vs. ProzacIf there's one thing Big Pharma fears more than anything else it's competition from the outside. Because herbal medicines have far fewer and less serious side effects than prescription pills, they would be the logical choice - if only they worked as well. Well, there is now irrefutable, ironclad scientific evidence that an herbal remedy is every bit as effective at treating depression as one of the most popular prescription antidepressants. When researchers with the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India conducted a controlled clinical study comparing the effects of curcumin and Prozac, they didn't expect to make national, even global news. Although the popular herbal remedy is widely used in India, curcumin had never been subjected to rigorous scientific testing for the treatment of major depressive disorder (MDD). The most serious and chronic form of the disease, major or clinical depression affects about 3 percent of population at any given time. The idea that a chemical compound from a popular native spice could compete with Prozac seemed far- fetched to those conducting the study. But after 60 patients diagnosed with MDD were randomly administered curcumin, fluoxetine (Prozac), and a combination of the two, the results spoke for themselves. With the help of the Hamilton Depression Rating Scale, 17-item version (HAM-D17), researchers determined that curcumin was just as effective as Prozac at treating serious depression. Because the study utilized the latest research tools and followed strict testing guidelines, it became the first published report that indicated the efficacy of turmeric or curcumin in the treatment of depression. What the report did not take into account, however, were the serious side effects those who take Prozac endure; the most serious of which include anxiety, seizures, racing heartbeat, trouble sleeping, and suicidal ideation. How Curcumin Treats DepressionShortly after the results of the aforementioned study made news, researchers started looking for answers. It was not enough for Western scientists to know that curcumin is effective in the treatment depression, they also had to know how. As you might imagine, the how has proved more challenging than the if. This is not at all surprising, since curcumin has diverse biological properties that are difficult to study separately. So, while the mechanism of action is poorly understood, the effects of curcumin intake are well documented, particularly with regard to neurotransmitters. As their name implies, neurotransmitters send messages to the billions of neurons in the human brain. Some of these neurotransmitters are responsible for regulating brain functions such as mood, memory, appetite, and sleep. Known as "feel-good" neurotransmitters because they help maintain mood balance, dopamine and serotonin play a role in depression. How do we know? For starters, studies have confirmed that people who suffer from clinical depression have consistently low levels of both neurotransmitters. Once again, we aren't sure how curcumin extract works its magic, but testing has shown that those who take it have higher serotonin and dopamine levels. That fact alone might account for the improved mood those that take the dietary supplement have consistently reported. Although researchers will undoubtedly get to the bottom of this ancient mystery, it enough for most patients to know that curcumin is a safe and effective treatment option. Related Products //vitanetonline.com/description/90352/vitamins/Curcumin/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3332) The Most Powerful Antioxidant known to man.
Date:
August 10, 2016 04:46 PM
The powerful antioxidant I am taking about is Curcumin. ORAC (Oxygen Radical Absorbance Capacity), is a Scale that measures foods antioxidant power. BCM-95 is a patented curcumin extract, that has a higher absorption rating than other curcumin products on the market. one gram of BCM-95 is said to have 15,000 ORAC score. Compared to blueberries which have a 600 ORAC score per gram of berries. BCM-95 is 25 times stronger than blueberries gram for gram. In order to maintain health and prevent disease, we need to consume lots of antioxidant rich foods. Taking BCM-95 curcumin can help prevent and reverse diseases you may or may not have. A diet change is essential to maintaining good health, but if dietary changes are difficult, adding a supplement like BCM-95 curcumin can have the same effect. What is stopping you from making life changes?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3254) Can Argan Oil Help My Skin Look Younger?
Date:
September 17, 2015 10:19 PM
Argan oil has risen to become a very important component when it comes to skin care. The trick lies in its composition. Unlike other products in the same class, it has a very unique composition. This oil has sterols, polyphenols, carotenoids, natural antioxidants and not forgetting essential fatty acids. Below are some of the skin problems that can be cured by Argan oil:
Sunburn refers to dry scaly skin condition as a result of being exposed to intense sunshine. Argan oil is high in vitamin E content which plays a very big role in curing this condition. It helps prevent sunburns due to its moisturizing ability. However, in cases where the sunburn has already occurred it can be used to treat the condition. Due to this particular quality; vitamin E has been linked to preventing skin cancer.
As people age, the skin tends to lose its elasticity quality and as such wrinkles begin to appear. However, this oil helps to prevent and/or cure this problem. It does this by rehydrating the skin, hence restoring the skin’s natural elasticity properties.
Psoriasis is a disease that affects the skin. Its main symptoms are appearance of red patches on the skin covered with Scales. The compounds present in argan oil help alleviate the problem through nourishing it with essential nutrients. As a result it helps the skin retain moisture, effectively treating the condition.
Have you ever experienced rashes that arise due to after-shave? This condition is very common in men after shaving as well as women after shaving their legs and/or bikini lines. These bumps are very uncomfortable and unsightly. Argan oil has been proven to heal this condition. Regular use of argan oil is not just for cosmetic purposes, but majorly for the general health of the skin. Its many unique natural compounds do not only preserve and soften the skin but also help in healing various skin conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3218) Is Cocoa Butter Good For The Skin? Why?
Date:
March 06, 2014 03:27 PM
Cocoa butter Doubtlessly, there are few preferred healthy skin items over cocoa butter and some few that likewise makes you feel great deductively notwithstanding feeling extraordinary because of the way your skin looks so great, but Cocoa butter is good solid skin reinforcement, and for additional data on characteristic healthy skin items with a great experimental foundation. Therefore it is good for the skin. Reasons to why cocoa butter is good for your skin: Powdered cocoa butter contains a lot of diverse antioxidants which behave synergistically presenting a massive bothersome resistant to the cost-free radicals which eliminate your skin layer cells along with lead to quick getting older. Therefore, therefore, is it doesn't suitable natural skin care solution. Let's have a look at which record again. Precisely why your 'ideal' natural skin care solution? In order to solution which question, we need to have a look at precisely what antioxidants tend to be, along with precisely what hot cocoa butter can perform them, along with after that the reason why it is advisable than additional natural skin care merchandise on the market. Totally free radicals tend to be small substances kinds in the body's fat burning capacity while vitality is generated coming from blood sugar in the mitochondria of each and every cell phone within your body. Fortunately they are shaped simply by experience of toxins including pesticides, along with particularly the several poisonous pieces of cigarette light up. Cigars along with water lines tend to be believe it or not harmful than tobacco, along with filtration system guidelines make not any difference towards the production connected with cost-free radicals. What exactly that they do is always to eliminate cells, when they're pores and skin cells you continue to grow older. Your skin layer wrinkles along with dries up, and you begin to take on the style connected with an individual many years over the age of you're. These people try this by way of a procedure often known as oxidation, along with antioxidants can certainly keep the idea. These people reduce the effects of your cost-free radicals, and forestall your skin layer cells coming from getting ruined. Contents of cocoa Powdered cocoa butter contains several different antioxidants that can eliminate away from numerous diverse cost-free radicals along with superoxides, as well as hydrogen peroxide. Vitamin e is really a powerful antioxidant -- your strongest of all the so-called antioxidant vitamin supplements in fact, and will quickly eliminate away from hydrogen peroxide along with any oxidizing agent. Others tend to be vitamin supplements A new along with G, however they can not strategy the potency of vitamin E. Furthermore, it contains phytochemicals (posh title pertaining to place chemicals) including flavanoids which might be also powerful antioxidants. Polyphenols are very effective in neutralizing cost-free radicals, and the hot chocolate mass polyphenols tend to be in particular successful. In fact, hot chocolate butter boasts a greater antioxidant awareness and then possibly blueberries as well as other so-called superfoods. In order that hot cocoa butter to work, it will email numerous of the pores and skin cells as is possible, that involves do away with the idea properly directly into your skin layer. The epidermis is incredibly absorbent all of which will eliminate cost-free radicals in the reduced absolute depths of the pores and skin as soon as they're created, along with ahead of they are able to do injury. It is clinically demonstrated which hot chocolate butter will certainly keep pores and skin degradation a result of the harmful consequences from the UV light in the rays of the sun -- UV rays builds cost-free radicals which are very effective in doing damage to pores and skin. Merely go through the influence connected with sunburn! However, there is additional in order to hot chocolate butter than which. It contains a substantial percentage connected with vitamins as well as lime Scale, potassium, magnesium, zinc, manganese, copper along with metal, all of which come in a highly bioavailable style which make them far better which business vitamins. Not just that, though. Furthermore, it contains tryptophan, involved in the development connected with serotonin, your 'feel good' neurotransmitter, and also dopamine along with phenylethylamine, many beneficial materials. It is a mental faculties food as well as food to your pores and skin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3049) What Health Benefits Juniper Berry Oil Posses
Date:
February 19, 2014 03:18 PM
What is juniper berry With regards to Super foods, berries are right on top of the agenda on the grounds that they are packed with gainful cell reinforcements. One such berry that can help you a great arrangement is the juniper berry oil and through the years, experimental exploration has indicated what a wonder it is. Organically talking, the juniper berry isn't a real tree grown foods yet the juniper's seed cone. It's viewed as a berry as a result of its Scales. The juniper is an evergreen tree and there are obviously 6 types of this tree whose berries are palatable and utilized for a ton of useful purposes. Juniper berries oil are widely utilized within European cooking, particularly meat based arrangements as it gives one of a kind quality. Gin significant others likewise may be amazed to discover that juniper berries are the essential element in gin. However the juniper berry is eminent for its notoriety as a home grown answer for an unimaginably long rundown of conditions and afflictions. How it makes a difference The juniper is truth be told a helpful tree as a large portion of its parts are utilized for a medicinal readiness or the other. In this way, the berries, leaves, bark and even oil determined from the berries and wood are utilized within different ways. Benefits of juniper berry Basically a severe berry, the juniper berry holds various unpredictable oils or key oils, strand, vitamin C, flavoring and entire parcel of dynamic fixings that makes it the achievement healer that it is. Note that juniper berries might be taken as teas and the squashed berries could be connected on the skin also for an assortment of sicknesses. Here is a glance at a portion of the employments of the juniper berry and how it can help us lead healthier lives: Juniper is recognized to be a herb with the most astounding consequences for kidneys. It is additionally used to cure different urinary tract contaminations and it can uproot uric harsh corrosive from the figure. Juniper makes the kidneys work rapidly and the form transforms more pee, making it a great diuretic additionally. People confronting water maintenance issues can feel a great deal of alleviation with the juniper berry and its oil due to its diuretic lands. Oil from the juniper berry has a disinfectant impact and it comes as an extraordinary easing to individuals experiencing urethritis and cystitis. Suffering from digestive issues? The Berry may very well be your reply as it can help diminish tooting and colic and help processing. It additionally moves issues, for example, bloating, belching and acid reflux. As a digestive help, it is remarkable as it expands the longing, soothes gas and expansions the generation of gastric harsh corrosive. Juniper berry oil additionally has calming qualities and it is of superb assistance to those experiencing joint inflammation, gout and different conditions, for example, ailment. These joint related ailments happen due to the liquid maintenance around these joints and the juniper berry with its diuretic activity assuages this weight extensively. Skin afflictions, for example, dandruff, skin inflammation and contender's foot can additionally be treated with topical provision of the juniper berry. Juniper helps in invigorating the muscle tone and discernibly decreasing the impacts of ageing for generally individuals. Menstrual spasms are frequently a significant number of the most troublesome parts of a lady's life; however these can additionally be lessened fundamentally with the assistance of the juniper berry. Numerous cultivators even utilize the juniper to enhance the uterus tone and to help the individuals who have moderate or late beginning periods. Concentrated oils of the juniper are utilized topically for lung clogging and hack while it is additionally pivotal in helping those experiencing respiratory contaminations. The unpredictable oils help in clearing up bronchial entries and disposing of bodily fluid. It has a high convergence of insulin and aides in mending the pancreas. Essential oils extricated from juniper berries can help in soothing toothache and making gums stronger. It can additionally be utilized to oversee hair fall. Finally, the juniper berry is utilized by numerous to thin down and since it even scrubs the poisons from the form, it is an extraordinary general purifier also. Safety measures Juniper does have some noteworthy symptoms and its vital that you're attentive to them before you begin utilizing them as any type of medicine. Avoid the juniper berry oil in the event that you have extreme kidney issues as it can disturb the issue and cause further harm. If you utilize more than the endorsed sum, chances are that you could experience the ill effects of loose bowels, kidney torment, high circulatory strain, quick pulse and purplish pee. When taken inside, it can affect the assimilation of iron and different minerals. Open wounds are best not treated with juniper on the grounds that it can cause inconvenience and swelling. Juniper causes uterine fits and could prompt brought down ripeness, so ladies who are endeavoring to get pregnant must escape juniper. Pregnant ladies ought not to utilize juniper as it can cause uterine compressions and reason a premature birth. Diabetics must be cautious while utilizing juniper as it can raise the levels of glucose in the form. Juniper when taken in prudent sums and with individuals, who don't have the shown issues as said above, could be a blessing as it furnishes them with a considerable measure of help.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3025) What Are The Benefits Of Pure Hempseed Oil?
Date:
March 18, 2013 04:40 PM
Hempseed oil is oil that is obtained from hemp seeds. Unrefined Hempseed oil that is cold pressed is green in color and dark to clear light. It also has a nutty pleasant flavor. If the Hempseed oil has a dark the color then the flavor becomes more grassier. Refined hemp oil is colorless and clear with little flavor. It lacks antioxidants and natural vitamins. Refined Hempseed oil is used primarily to manufacture products of body care. Industrial Hempseed oil is used to produce paints, lubricants, inks, plastic and fuel. This oil has also found some limited use in industries that produce shampoos, detergents and soaps.
Hempseed has had a good relationship with humanity. Hempseed high in fatty acids Studies that have been conducted recently shows that it contains essential fatty acids and amino acids that are necessary for human life. It also has a rare protein referred to as globule Edestins that is similar to Globin that is fond in blood plasma of humans.
Pure Hempseed oil has high nutritional value because it consist 1:3 ratio of omega 3 to omega 6 essential fatty acids .This ratio matches with the balance that human body requires. In recent years, it has received attention as possible feed stock for large Scale production of bio-diesel. This oil makes incredible cosmetic grade oil and quality dietary oil that are superior because of its high nutritional value. It is used also as a skin care recipes because it has base ingredients that helps the skin to regenerate and heal. Pure Hempseed oil is highly emollient and this property makes it to be used to regenerate and nourish the skin directly. Hempseed oil is capable of penetrating the skin deeply unlike other oils that sits on top of the skin. Its deep penetrative property prevent the skin from aging because it allows essential fatty acids to penetrate the outer layer of skin fully thus encouraging a healthy moisture balance. Hempseed oil contains a rich balance of essential oils Pure Hempseed oil contains one of the richest and balanced natural sources of essential oils that are good for human consumption. The essential fatty acids help to restore wasting bodies and also improve immune system that is damaged. It is therefore not a surprise that modern researchers have studied this oil in relation to modern immune that attacks AIDS virus. Hempseed oil is surely nature's oil that is most balanced for human nutrition (1:3 LNA to LA ratio) and it can be digested easily. In fact, modern research indicates that this oil can provide all our essential fatty acid requirements for life. Rich in Omega-3 This is made possible because it has a balanced 80 percent essential fatty acid content of the oil. Omega 3, a component that is found in Hempseeds helps to prevent: growth retardation, motor in coordination, tingling in legs and arms, behavioral changes, visual impairment and learning inability, high blood pressure, high triglycerides, tissue inflammation, dry skin, edema, low metabolic rate, sticky platelets and other kinds of immune dysfunctions. Rich in Omega-6 Omega 6 a component that is also found in Hempseeds helps in preventing: loss of hair ,skin eruptions ,liver degeneration ,kidney degeneration ,behavioral disturbances, drying up of glands excessive water loss from the skin that is accompanied by thirst, failure of wound healing ,susceptibility to infections ,growth retardation sterility in males ,arthritis like conditions, miscarriage in females, circulatory and heart problems. Prolonged absence of both omega 3 and 6 in your diet can be fatal and should be avoided. Pure Hempseed oil is is ideal to be used in mayonnaise, dips and salad dressing because of its nutty pleasant flavor .It can be taken as an additional supplement for well being and general health. However it is not suitable to be used for frying because its benefits are reduced.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2832) History And Uses Of Xylitol
Date:
February 07, 2012 07:50 AM
Xylitol is the 5-carbon sugar which is found within the birch tree sap and it's naturally found in the fibers of various vegetables and fruits. This is a sugar-alcohol sweetener commonly used as the sugar substitute. History of xylitol Although discovered in the 19th century during the Second World War, Xylitol has been recognized ever since the tardy 1800s. The researchers from Germany and France were the first individuals to try to produce this product approximately 100 years ago, but ended up creating syrup-like consistency mixture. This product became commercially available in the 1960s and the commercial process is still the same as it was during the 1960s. Before 1943, the scientists' categorized this sugar with various sugary carbohydrates (polyols) and it lingered so till the beginning of the war-associated deficiency of sugar which initiated the call for an alternate sugar. This initiated further research in to the xylitols insulin-independent properties, this resulted in discovery of its other biological benefits. In 1962 this chemical was introduced in the infusion therapy demonstrating that it can be introduced to ill individuals. The commercial production process involves extraction of Polysaccharides rich in Xylose from various agricultural by-products and hardwoods. These are hydrolyzed with various intense acidic treatments and then it is purified before hydrogenation is done. This process needs a lot of harsh chemicals and is quite expensive and inefficient. It was until 1970 that the odontological benefit of xylitol was ascertained in Finland, Turku. The initial study of the effects of this sugar on the dental plaque began during the same year. This resulted in large Scale production of xylitol, in 1974 by the Finnish sugar company. Sugar-free dental product was first launched in Finland which was a xylitol chewing-gum. How xylitol works This sugar can prevent cavity in various ways by actually blocking the tooth decaying process. The bacteria causing decay cannot ferment this sugar into acids as it does with other sugars including dextrose, fructose, glucose and sucrose. This results in production of less acidic by-product thus interfering with the dental plaque environment which favors decaying. This results in prevention of tooth demineralization. The high pH condition caused by xylitol sugar is not favorable for the cariogenic bacteria which are responsible for decaying. This results in fewer bacteria in the plaques and long-term exposure has an effect on which type of bacteria will prevail within the plaque. This also inhibits the growth of specific xylitol-sensitive bacteria strain. Since they cannot breakdown this sugar, they end up not reproducing and growing in population. The lack of fermentable sugars results in creation of anti-cavity effect. The starvation effect created by this sugar prevents accumulation of cariogenic bacteria in the plaques. Long term xylitol exposure results in change of predominant cariogenic bacteria to xylitol-resistant strains from xylitol-sensitive. This xylitol-sensitive strain of bacteria cannot colonize the plaque since they have less adhering capabilities. The less acidic condition in the dental plaque interface created by this sugar can initiate demineralization. Demineralization occurs when the plaque interface is at a pH of 5.5 or below since fewer bacteria live in the plaques. Studies have showed that demineralized tooth samples immersed in a solution containing 20% xylitol experienced a great remineralization degree. This is noted in the deep and middle tooth layers.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2558) Does Stress Deplete The Body Of Minerals?
Date:
September 24, 2011 04:06 PM
Minerals Heavy traffic after a long day’s work, trying to sleep and your neighbour’s dog keeps barking and when you wake up in the morning your kids show you their report cards and they failed a couple of subjects then you’re late in getting to work because you had to have that discussion with your kids, you get called off into the boss’ office and he tells you that what you’re doing and the reasons behind it are unacceptable. That’s stress, in the modern world many people believe although there are no conclusive studies about it yet, stress is the number one silent killer in the world. I mean think about it, aside from the health implications, how many violent acts have been caused by stressed People? Every day in the news you see stressed out people doing things they probably will not do otherwise had they controlled there stress factors. Stress and its health effects though in a more minor Scale has been proven to exist like stress induced ulcers or allergies induced by stress so having more detrimental effects to the health is not that far fetch. So in the question of whether the body can be depleted by stress of minerals I would say yes however more than that lets find out how. Stress and Minerals Commonly stress is triggered by environmental circumstances which in turn if left unattended can lead to depression however recent studies have come across more evidence that the true culprit maybe a chemical imbalance in the brain. This is where we see that initial relationship between stress and minerals as certain mineral depletion in the body can lead to inefficient functioning of vital organs and one of them is the brain which is where stress just like any other emotion we have originates. In the US, modernisation has depleted our soil of its mineral contents which in turn also affects the food we eat. Aside from food intake, mineral deficiency can also be caused by an underlying heath issue that an individual may have. From diarrhea to malnutrition the possibilities are wide. Another way that stress has been proven to be related to minerals is in the way it is absorbed. Many studies have shown that some minerals are affected by stress due to inhibiting its absorption in some way. The key for this inhibition property of stress for proper mineral absorption is in the chemicals and hormones it initiates the body to release. When the body is stressed, the normal response for it is to release hormones and chemicals such as adrenaline, noradrenaline and cortisol. These substances counteract the efficient absorption process that our body otherwise will have if they were in absence. Different minerals maybe affected in different ways but nonetheless affected. Calcium for example will not be absorbed well by the bones in the presence of cortisol and with high adrenaline levels magnesium may be lost through urine and potassium is another mineral that does not react well with cortisol and has marked stress as an inhibitor for its absorption because of this.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2458) What is Schizandra Fruit Good for?
Date:
May 17, 2011 02:57 PM
Schizandra and your Health.Schizandra fruit refers to the berries of schizandra. It is widely used in China and the plant is considered one of the 50 fundamental herbs in Traditional Chinese Medicine. It is a highly prized ingredient to a health tonic historically prepared for Chinese royalty and nobility. In recent years it has become available to more people across the globe as cultivation increases to meet large-Scale productions. Also, herbal supplements that contain extracts of schizandra fruit are becoming popular. Schisandra chinensis is an indigenous plant species of, as the name suggests, China. However, its native range goes as far north as Asiatic Russia. It is cultivated for its leaves, bark, and berries. The name of the fruit in Chinese translates as “the berry that possesses all five basic flavors,” inasmuch as the Chinese believe it contains organic compounds responsible for its unique taste: salty, sweet, sour, bitter, and spicy. The berries are often dried and made into tea that can be served hot or cold. Scavenges Reactive Oxygen Species Reactive oxygen species, or ROS, are natural by-products of cellular respiration, the process of energy metabolism that takes place within each individual cell. These include peroxides, singlet oxygen, and free radicals. ROS can interrupt cellular activities and even damage DNA synthesis, the reason why each cell has its own antioxidant defense. That being said, cells are overwhelmed by ROS as we age. The process of aging has been tied to the weakening antioxidant defense of cells. Free radicals are also believed to be responsible for the fast progression of many life-threatening diseases, such as cancer. Schizandra fruit is a natural remedy for oxidative stress, the cellular damage brought on by ROS. The berries are rich in antioxidants that help replenish the antioxidant stores of the body. Displays Hepatoprotective Properties Schizandra fruit is particularly good for the liver. Practitioners of Chinese herbal medicine believe that its berries rejuvenate the liver, the kidneys, and the circulatory system by washing away the toxins these tissues have amassed over the years. The cleansing properties of juices and tinctures that contain schizandra have been ascribed to the organic compounds naturally occurring in the fruit. Lignans are a class of polyphenolic substances that occur naturally in nature. Schizandrin, deoxyschizandrin, gomisin, and pregomisin are lignans unique to the schizandra fruit. The antioxidant properties of lignans are well established, but those found in the berries of this plant species have an affinity toward hepatocytes, or liver cells. It protects liver cells from oxidative damage and raises the capacity of liver to deal with drugs and their harmful metabolites during first pass metabolism. Increases Physical Working Capacity Schizandra fruit is a symbol for youth in the East, and for good reason. For one, it is an adaptogen that increases tolerance to stress and raises the physical capacity of the human body. It is also an aphrodisiac believed to enhance libido and improve sexual performance. Modern herbalists believe its aphrodisiac effects are attributable to its stress-relieving properties. You too can experience the health benefits of schizandra by picking up a bottle at your health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2296) Liver Protection With Lipoic Acid and R-Lipoic Acid
Date:
May 05, 2011 03:42 PM
Early biochemistry studies pioneered by Linus Pauling associated R-Lipoic acid with orthomolecular medicine in that proponents argued that it biological roles provide protection against diseases. Succeeding research in the latter half of the 20th century supported its status as an essential nutrient, but more recent studies proved that all it is produced in vivo by almost all mammals, including human beings. In the past few years Lipoic acid has been strongly linked to glutathione as its supplementation appears to raise levels of endogenous glutathione. Strengthens Antioxidant Defense Lipoic acid is believed to raise the antioxidant capacity of the human body. Its biological roles benefits all cells, most notably hepatocytes, the cells that make up a significant fraction of the liver. For one, it affects productions of glutathione throughout the body. Glutathione is tripeptide that protects cells from the damage caused by reactive oxygen species, such as free radicals. Furthermore, it is a major transport of toxins found in the systemic circulation, facilitating their excretion through the urine. R-Lipoic acid has been observed to be the form of Lipoic acid that is capable of activating nuclear factor erythroid-derived-2-like 2, commonly abbreviated as NFE2L2, the protein that binds to DNA sequences responsible for regulating the antioxidant defense of the human body. Proponents believe that oral intake of R-Lipoic acid produces more visible results than its racemic counterparts. Displays Higher Bioavailability Research on Lipoic acid is one of the most advanced, starting in the 20th century and spanning over 5 decades. It is widely accepted that the forms available in the market are not bioequivalent. Most of the studies in the 1950’s utilize the enantiomer S-Lipoic acid and R/S-Lipoic acid race mixture because they were cheaper to produce. Recent developments in chiral chemistry have increasing allowed for large-Scale productions of R-lipoic acid. Many scientists today believe that R-Lipoic acid is superior to racemic forms. Its rate and extent in availability after oral administration has been noted to be far better, and thus its efficacy is expected to be more remarkable. It is postulated that its higher bioavailability allows it to effective fill the roles of endogenous lipoic acid, not to mention manage to influence the master regulator of antioxidants. Shows Vitamin-like Properties The popularity of R-Lipoic acid lies in vitamin-like properties. Researchers are particularly enthusiastic about its purported benefits on human health, though more studies are needed. It is one of the organic compounds needed for enzyme function just like vitamins, and supplementation is believed to produce preventative benefits against diseases. Its pervasive roles at the cellular level enable it to affect energy metabolism, leading to healthy weight loss.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2287) How Does Nattokinase Help Improve Cardiovascular Health
Date:
April 29, 2011 04:01 PM
Nattokinase And Your HealthNattokinase is an organic compound that occurs naturally in the Japanese food natto, or fermented soybeans. It is an enzyme that acts on fibrous proteins responsible for blood clothing, and as such has been commercially touted to work like thrombolytic medications to a certain degree. Its synthesis involves fermentation that results from adding the bacterium Bacillus subtilis to boiled soybeans. Natto is a traditional dish in Japan. It has enjoyed long-standing popularity among the Japanese people since feudal times largely owing to its reinvigorating effects on the blood. In recent years, laboratory studies point to the presence of chemical compounds in fermented soybeans. The enzyme nattokinase appears to be the active ingredient, improving fibrinolytic activities in animal subjects. Breaks Down Blood Proteins Proteases are enzymes capable of reducing proteins into smaller peptide chains in the digestive system or anywhere in the body. A special kind of protease called plasmin is found in the blood. It is the primary enzyme that facilitates the catabolism of fibrin clot, or coagulated blood protein. Fibrinolysis is the process initiated by the enzyme plasmin to dissolve compacted red blood cells. Thrombolytic drugs work on the principle of raising the levels of plasmin in the blood. Streptokinase is one of these drugs. It is commonly administered in the treatment of myocardial infarction, or heart attack to avoid complications. Natto has been compared to streptokinase, and oral intake of nattokinase has been observed to stimulate productions of plasmin. Prevents Blood Coagulation Nattokinase has been extensively studied in Japan, though well designed large-Scale randomized clinical trials are still needed to establish its purported benefits to human health. There is buzz around nattokinase in the pharmaceutical industry especially as early studies suggested that it may ameliorate complications of cardiovascular diseases, notably in the removal of platelet-fibrin emboli. There have been numerous citations on the blood-thinning capacity of nattokinase. This enzyme is also believed to have an inhibitory effect on platelet aggregation. Thrombocytes, or platelets, are necessary for containing excessive bleeding. However, aggregation of platelets may result in thrombosis in patients with history of atherosclerosis and other disorders of the blood vessels. Nattokinase is a blood thinner that affects both platelets and fibrins. Improves Cardiovascular Health In addition to its thrombolytic and anticoagulant properties, nattokinase has been reported to promote normal flow of blood. Natto has been linked to the alleviation of high blood pressure and has seen desirable outcomes in hypertensive patients. Recent studies have shown that nattokinase is responsible for producing antihypertensive and vasodilator effects when natto enters the systemic circulation. It is postulated that nattokinase inhibits angiotensin-induced vasoconstriction. The Japanese have always believed that natto is good for the blood. Nattokinase remains under scrutiny, but clinical trials are well underway. A growing body of literature devoted on promoting its alleged health benefits draws so much on decades-long anecdotal evidence. If you want to improve cardiovascular health, give Nattokinase a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2285) Does Aloe Vera Juice Help with Digestive Problems?
Date:
March 28, 2011 02:01 PM
Aloe vera and your ColonAloe vera juice is one of the oldest herbal remedy for digestive problems that up to now remains in common use. It is extracted from the succulent plant aloe vera, which is known for its medicinal properties all over the world. Cultivation of this medicinal aloe predates written history, and its place of origin has eluded scholars for centuries. The fact that it is widely distributed across the globe today makes it a ready source of medicine in treatment of common digestive ailments. Also, large-Scale production has contributed to its growing popularity worldwide. You may have heard of aloe vera juice as a health tonic. Folk medicine practices in just every continent highly value this medicinal aloe for its cleansing properties, but the first recorded use for illnesses of the gastrointestinal tract is in an Egyptian medical papyrus. In Greek and Roman antiquity aloe vera extracts in the form of juice were prescribed by physicians who practiced humorism to patients afflicted with constipation, diarrhea, indigestion, and stomach cramps. Both De Materia Medica by Greek botanist and pharmacologist Pedanius Dioscorides and Naturalis Historia by the Roman natural philosopher Gaius Plinius Secundus made mentions of its medicinal powers known to cleanse not only the alimentary canal but also the blood. Heals Ulcerations of the Gastrointestinal Tract It is common knowledge that aloe vera promotes the healing of wounds and other skin lesions. Aloe vera juice works on the same principle when ingested. This medicinal plant contains phytochemicals that increases the rate of healing of skin lesions and damaged epithelial cells of the gastrointestinal tract. There is a growing body of literature devoted to the effects of this medicinal aloe on inflammatory intermediaries present in the processes that are implicated in lesion of body surfaces, including the inner walls of the alimentary canal. Inhibits Growth of Harmful Strains of Bacteria Aloe vera juice has long been postulated to have antibacterial properties, and scientific evidence in support of this claim has surfaced in the past few years. One of the reasons why aloe vera speeds up the recovery of wounds is the fact that it is both bacteriostatic and bactericidal in nature, which means it inhibits the growth of bacteria and actively eliminates them at the same time. In addition, aloe vera contains polysaccharides that benefit probiotics, or friendly bacteria. By raising the number of helpful strains of bacteria such as lactobacillus, populations of harmful bacteria are curbed. Induces Peristaltic Movement of the Intestines There is strong scientific evidence that aloe vera juice is particularly beneficial for individuals afflicted with constipation. For one, anthroquinone glycosides found in aloe vera have been noted to accelerate defecation by adding bulk to the impacted feces and attracting water to soften the stool. Furthermore, aloe vera stimulates the muscle cells within the intestinal walls, which consequently produce contractions. The resulting peristaltic movement moves the ball of food, leading to the evacuation of the bowels. Aloe vera is an excellent remedy to take daily to maintain good intestinal health as well as skin health. Take your aloe daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2260) Agave Nectar
Date:
April 08, 2010 04:31 PM
Comments by Craig Gerbore, CEO of Madhava: Reading through the attack articles and blogs that have surfaced recently one could think that using agave is bad for one's health. These claims are utterly false and misleading. They are extreme views drawn from extreme examples and applied way out of context. They are propagandizing and clearly designed to frighten, not educate. All of the fears and concerns associated with the overconsumption of sugars and calories in general have been unfairly cast on agave. What is a "healthy" sweetener? One that you use moderately and sensibly. Health concerns related to fructose and caloric sweeteners are all dependant on the overconsumption of them. All foods have calories and it is the overall consumption of calories that lead to obesity and related issues, not any one food source. Agave's caloric value is comparable to the other sweeteners in the category. Due to its greater sweetness though, less agave is used compared to the others, so agave actually can reduce caloric consumption per serving. This is due to a higher fructose content. The higher content does not mean higher consumption though, due to the smaller portion used. But, it is not the single serving that matters, it is the number of servings which lead to the overconsumption issues which may result in health concerns. As a reference point, 9-10 teaspoon servings of agave would be the approximate caloric equivalent of one 16 oz soft drink. With this perspective, is agave really being overconsumed as a choice of sweetener for home use? Every single health issue which the attackers have tried to associate with agave is really the result of a caloric overconsumption issue. There are no documented issues with normal, moderate consumption of agave or sweeteners in general as part of our everyday diet. For reasons unknown, some have attempted to isolate agave from the real world and real world conditions with the goal of inhibiting agave's use. They play on people's fears, reference false information and fail to address health issues in any meaningful way. The purpose of this article is to debunk the controversial misinformation surrounding agave. All information debunking the myths and misinformation is based on current science and facts. It is our goal to provide you with useful information so that you can make your personal nutritional choices in a well-informed, science-based manner. The Agave Controversy: Exposing the fraudulent article by Rami Nagel By Dr. Susan Kleiner, PhD, RD, FACN, CNS, FISSN And Craig Gerbore, CEO Madhava The controversy about agave syrup was manufactured by the publication of a single article on the internet, which has been reproduced and adapted for virtually every other article produced on the internet and other media venues. That article, written by Rami Nagel and published on Naturalnews.com, was highly biased and full of inaccuracies, half-truths and misinformation about agave. Since the Naturalnews.com article has been the sole source of nearly all other popular articles in public media, we want to set the record straight with science-based, reliable information to offer a more balanced resource to those interested in learning more about agave syrup. Who is the author, Rami Nagel? According to the description on the Naturalnews.com website, Rami Nagel is a "citizen journalist". This means that Mr. Nagel is self-employed, and not employed as an in-house journalist by the website. He wrote and published the article without any editorial or content oversight, and the editor of the website, Mike Adams, makes it clear that the article was not checked for incorrect or inaccurate information or facts. The introduction to the article, written by Mr. Adams, states that readers had written to comment that Mr. Nagel's resources were biased with conflicts of interest due to their financial interests in competing sweeteners, such as brown rice syrup. So even the website editor himself states that the article is not fact-checked, and it is biased and unbalanced. Who is Russ Bianchi? The sole resource interviewed for the article is Russ Bianchi, identified by the author as Managing Director and CEO of Adept Solutions, Inc. Mr. Bianchi has clear conflict of interest ties to the sweetener industry. We have documentation of the fact that Mr Bianchi had plans to market a product named Replace. It was to be touted as a low calorie alternative sweetener composed of natural and artificial ingredients! Mr Bianchi was prevented from marketing this sweetener as the result of a lawsuit against him by the owner of the formula. Mr Bianchi is quoted by Nagel extensively and exclusively. Many, if not all, of his statements are blatantly false or misrepresentations of fact. He is clearly propagandizing against agave nectar. Was anyone else interviewed for this article? Yes. Craig Gerbore, president and owner of Madhava Agave Syrup, was extensively interviewed by the author but no parts of that interview were included in the article. It is important to note that neither Mr Nagel or Mr Bianchi have not made themselves available for questions on their statements since the articles appearance. They remain out of sight and have entirely avoided the controversy their statements created. What is agave nectar? The opening line of this paragraph in the article by Mr. Nagel states: "The principal constituent of the agave is starch, such as what is found in corn or rice." This is absolutely false. There is no starch in agave. The source of carbohydrate in agave syrup is inulin, a polysaccharide made up primarily of strings of fructose units. Starch is a polysaccharide made up of strings of glucose molecules. They are significantly different, and this difference is why agave syrup is naturally sweet. The very basis of the argument presented by Mr. Nagel is false. The Process The agave plant is a succulent, similar to a cactus. The agave sweetener comes from both the Salmiana agave plant and the agave Tequilana (Blue Agave) which are both organically farmed in Mexico and certified organic by USDA approved certifiers. As the salmiana plant grows it produces a stalk called the "quiote" and when this is removed, a natural liquid called "aquamiel". The liquid is collected from the plant, while Blue agave pinons are harvested and shredded to remove the similar juice. Either can be naturally processed thermally or by enzymes into agave nectar. The juice of the plant is not naturally sweet. The string of connected fructose units that makes up the major proportion of inulin does not have a sweet taste, but when the fructose units are separated (the process is called hydrolysis) by the addition of an enzyme, similar to digestion, or thermally for most blue agave, the syrup becomes quite sweet. That is the entire processing chain for agave nectar. There are no additives, other ingredients or chemicals in Madhava agave nectar. It is absolutely pure and organic and GMO free. ? Mr. Nagel claims that agave syrup is a "refined corn fructose" similar to high fructose corn syrup. This is absolutely false. There is no relationship between agave syrup and high fructose corn syrup in any way, including the source of the product, or the manufacturing process. ? Mr. Nagel refers to a "confidential FDA letter" from Mr. Martin Stutsman, claiming that agave is fraudulently labeled. We contacted Mr. Stutsman at the United States Food and Drug Administration, and his response made it clear that there was never a "confidential FDA letter". He did publish a public letter referenced in an FDA document as "FDA letter from Martin Stutsman to Dr. Eric Wilhelmsen (Wilhelmsen Consulting), May 8, 2000", regarding evaporated cane juice, a topic wholly unrelated to agave syrup. ? He continued in his response to us that the paragraph in Mr. Nagel's article inaccurately reflected the substance of his comments in the document. This link will take you to the original document in which the letter was referenced (reference #2): //www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/FoodLabelingNutrition/ucm181491.htm In fact, Mr. Nagel fabricated the entire story of the letter. Mr. Stutsman is a lawyer, not a doctor. The quotes were completely taken out of context from the document, and the quotes never referred to agave syrup at any time. Nagel goes on to further misrepresent Mr. Stutsman's intent in the published document by weaving in other inaccurate information that is thoroughly unrelated to the original document. Mr Bianchi's subsequent statements on labeling issues are false and without merit. Mr. Nagel is clearly caught red-handed. He has misrepresented the words of a government official, lied about the facts, and twisted the information to achieve his own agenda. This strategy is repeated throughout the article. ? Mr. Nagel continues his deceptive writing by referring to a quote by the late Dr. Varro Tyler in his book, The Honest Herbal. The first line of the paragraph is a direct quote from the book. Nothing else in that paragraph remotely resembles anything else found in Dr. Tyler's book. Mr. Nagel is trying to claim that agave syrup contains large quantities of saponins, and that they can be harmful to health. Here is the debunking of that paragraph: 1. Dr. Tyler does not include the variety of agave plant used for agave syrup. 2. The entire discussion is about the use of the sword-shaped leaves and the stem. Agave syrup is produced from the natural liquid in the plant. The saponins are isolated from the leaves of the plant. 3. There is no documented evidence to suggest agave syrup contains worrisome levels of saponins and the entire rest of the discussion about health dangers is fabricated and false. Sugars People are going to continue to consume sweet food and drink. There are only three categories of choice to sweeten food. Those are artificial sweeteners, stevia, or caloric sweeteners from natural sources, sugars. Most people will not choose artificial. Many will not choose stevia. That only leaves the category of sugars. In this group, agave is a good choice due to its organic quality, ease of use, neutral flavor, low glycemic index and the fact that less is used to equal the sweetness of the others in the category. The sweeteners in this category are composed of three primary sugars used to sweeten foods: glucose, fructose and sucrose. These sugars belong to a class of compounds known as carbohydrates. "Saccharide" is a term that denotes sugar, or substances derived from sugar. Monosaccharides are simple or single sugars; disaccharides are derived from two joined monosaccharides and when they are hydrolyzed, or separated, they yield two molecules of simple sugar. Strings of more than two sugar molecules are called polysaccharides. This category includes compounds such as starches, cellulose and inulin. Glucose and fructose are monosaccharides. Glucose and fructose are found abundantly in nature in fruits and plants. Sucrose is the disaccharide formed by the joining of glucose and fructose, also known as table sugar. When comparing their relative sweetness, glucose is the least sweet tasting, sucrose is next, and fructose is the sweetest of the three sugars, measured as 1.4 times sweeter than table sugar. Because it is so sweet, people typically use less fructose when sweetening foods compared to sucrose. ? In the article by Mr. Nagel he states , "fructose is not what is found in fruit. Commonly, fructose is compared with its opposite and truly naturally occurring sweetener, known as ‘levulose' (made by nature)..." Another fabrication. In fact, levulose is just another name for fructose. There are various nomenclatures used in the scientific naming of compounds. Fructose and levulose are exactly the same thing; the names are interchangeable. It is no different than if you called your father, "dad", and your sibling called your father, "father". He would still be the exact same person. Fructose and levulose are different names for the exact same thing: a sugar found in nature. Mr. Bianchi also is quoted to say that the body does not recognize the fructose in agave. This is another false piece of propaganda which demonstrates just how far he is reaching. If this were true, it would have no impact on us. He immediately contradicts himself with the claims of detrimental effects caused by the overconsumption of fructose. Using Sugars Sugars can be compared to each other in their ability to raise blood sugar levels by using the Glycemic Index. The Scale is set from zero to 100, where low numbers do not have much impact on blood sugar levels, and high numbers raise blood sugar levels quickly. Fructose is very low on the Scale. Because agave syrup is high in fructose, it has a rating of 32 or lower. Honey, which has a higher proportion of glucose to fructose, has a Glycemic Index of 58. Sucrose has a Glycemic Index of 68, and glucose, serving as the index standard, is 100. All sugars, whether fructose, glucose, sucrose or others, contribute 4 calories per gram to our total diet. 1 teaspoon of sugar = 4 grams = 16 calories In addition to calories, sugars sweeten our foods offering a desirable taste and adding enjoyment and pleasure to our dining. During cooking and baking, sugars allow for browning and the unique consistencies of syrups, candies, frostings and frozen desserts. The varieties of sugars, such as crystallized table sugar, brown sugar, raw sugar, molasses, honey and agave nectar, among others, contribute different properties and flavors to foods. When you add your own sugar to foods you are in control of how much sugar you use. Most people would never add as much sugar as do the food manufacturers. Moderate amounts of sugar can certainly be enjoyed as part of a healthy diet for an active individual. Natural sugars are easily metabolized and utilized by the body, offering a very efficient source of fuel for physical and mental activity. Of course, sugars should be used in moderation in the diet. This can control calories and help create a diet that is dense in nutrients. Impact of sugar on health and disease ? The remainder of Mr. Nagel's article works to link agave syrup with the increased incidence of obesity, diabetes, metabolic disease, and the general rise of morbidity and mortality in the population. This is an overconsumption issue involving far more than the occasional use of agave. Here are the facts: • Rats that are fed a high fructose diet become obese and will develop the chronic diseases associated with obesity: insulin resistance, diabetes and metabolic disease. • No one should eat a diet that reflects this type of experimental diet. • Too much sugar in the diet, whether from fructose, glucose or sucrose, can be unhealthy. Diets high in sugar promote tooth decay and periodontal disease; create an overabundance of calories and a deficit of nutrients. This scenario typically leads to weight gain and the development of chronic disease. • Active individuals can include a moderate amount of added sugar in their diet without negative health consequences. When calorie intake is balanced with physical activity, sugar serves as an efficient source of fuel for muscles, the brain and the central nervous system. • According to the World Health Organization (2003), individuals can healthfully include 10% of their daily calories from added sugars. This translates into 200 calories for a 2000 calorie diet, or 12½ teaspoons of added sugar daily. Clearly, one can safely add a couple of teaspoons of sweetener to a cup of tea or coffee, or have a little sweetened food without worrying about their risk of developing disease. • Agave syrup, which is sweeter than other sugars and low on the Glycemic Index Scale, is a good choice to include as one of the added sugars in your diet because you will use less sugar (and therefore fewer calories) and minimally raise blood sugar levels. Just a teaspoon of agave: the healthy use of sweeteners in your diet We all want to live healthier and longer lives. Diet and nutrition plays a key role, impacting our health and our ability to perform physically and mentally now and into the future. Food offers us not only sustenance, but also pleasure and enjoyment. Food is present in so many parts of our lives: at celebrations, business events, family events, religious and spiritual occasions, sports outings, the focus of our family meals, intimate dinners, and sometimes just the excuse to socialize. Sweet foods make us feel good. Sugar allows for the elevation of serotonin in our brains, the "feel good" neurotransmitter that elevates mood, helps us focus, and in the evening, helps us relax and sleep. Sugar is a source of energy for our muscles, brain and central nervous system. Without sugar our bodies will not function at peak capacity. Too much sugar, however, is not good. In small amounts sugar energizes us, but in large doses, repeated throughout the day, day in and day out, sugar puts stress on the body. The extra calories can lead to weight gain and obesity, which in time can lead to chronic disease. In the short term, high sugar intakes can lead to a nutritionally deficient diet and a sense of being on an emotional roller coaster. So be selective about your use of sugars and use them in moderation in your diet. Just like all foods, a variety will enhance the nutritional content of your diet and the flavor and tastes that you can enjoy. Since sugars come in different forms and have different flavors, they can be used most effectively in specific foods and beverages. For instance, agave syrup is liquid and less viscous than honey, making it easy to mix into cold liquids like iced tea and coffee, and is great to add to cold unsweetened cereals for a little sweet taste. Agave's mild flavor allows chefs and bakers to sweeten foods lightly, without overpowering the taste of the dish. Pay attention to how much sugar is added to your diet every day. Read labels so that you know when sugar is added to manufactured foods. Keep the consumption of added sugars in your diet to no more than 10% of your total daily calorie intake so that you have plenty of room for nutrient dense foods like fruits, vegetables, grains, dairy, protein-rich foods, nuts, seeds and healthy oils. Remember that nutrition is a science based on facts. We are making great advances in our understanding of the science of foods and nutrition. Beware of people with hidden agendas using fear tactics to influence your choices. Don't take their opinion at face value. What are their credentials? What conflicts of interest do they have? If they do not disclose conflicts, then assume that they are manipulating the truth. Most of all enjoy food. Think about what you need to eat to promote whole health. Don't overindulge, but don't deprive yourself of the bounty of wonderful tastes, either. Use celebrations as occasions to enjoy your favorite foods and try new ones. A teaspoon or two of sugar easily fits into the diet of an active, healthy person. Agave syrup offers an organic low-glycemic choice for those looking for that option. Resources for this article: Charley H. Food Science, 2nd Edition. John Wiley & Sons, New York, NY, 1982. Figlewicz DP et al. Effect of moderate intake of sweeteners on metabolic health in the rat. Physiology and Behavior 98:618-624, 2009 Johnson RK et al. Dietary sugars intake and cardiovascular health: A scientific statement from the American Heart Association. Circulation: Journal of the American Heart Association, 2009 Tyler VE. The Honest Herbal, Third Edition. Pharmaceutical Products Press, New York, NY, 1993.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2152) Now foods and GMP Practices
Date:
February 04, 2010 12:36 PM
Author: Michael Lelah, Ph.D, Technical Directory, Now Foods It should come as no surprise that 2009 was a challenging year with regard to the timeliness of order delivery, not just at NOW, but on an industry-wide Scale. Many of the brands you carry have not been able to meet your demands. In 2009 all medium-sized dietary supplement manufacturers, including NOW Foods, were officially required to meet the FDA's new dietary supplement cGMPs (current good manufacturing practices). NOW has placed very high quality standards on our products, and has been certified by NPA's stringent GMPs since 2000. Now that the FDA has started auditing manufacturers in our industry, we have found that the FDA requirements for the cGMPs are more strict than the early interpretations of experts. This has resulted in ourselves and our industry being less prepared than anticipated, affecting the order fulfillment rates of many companies. We are actively working to respond to this. Let's review the new FDA cGMPs. Good Manufacturing Practices, or GMPs, are manufacturing control systems designed to ensure that health products are manufactured in a consistent and safe manner. Standard operating procedures, specifications for all ingredients and products, and lab testing are cornerstones of GMPs. The FDA cGMPs are considerably rigorous, and by the FDA's own estimates, 25% of the brands you carry could be out of business as a result of not being able to meet their new cGMPs. Moreover, even for reputable brands, there is a lack of clarity on what the FDA expects, as much of this is new. You might be wondering what all of this has to do with your orders? We at NOW Foods, along with other reputable manufacturers have increased our quality control efforts to meet the new FDA cGMPs. There are more requirements for ingredients and finished products, more documentation and more testing. The breadth of NOW's product line requires testing of thousands of ingredients. Based on the extensive nature of these efforts, coupled with disruptions in the supply chain, your orders have most likely been affected. We are now better prepared to serve you. We are taking the safety of our products to entirely new levels and doing everything in our power to expedite the delivery of NOW products to your door. Here are just a few examples of what we're doing:
Here's what you can expect from NOW Foods in 2010:
At NOW Foods we are continuing to work hard to meet your needs, despite the increased challenges to our supply chain. We hope and anticipate that as we move into 2010, you will reap the benefits of our quality and fulfillment efforts.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2123) Birch
Date:
August 21, 2009 12:08 PM
The birch species are generally small to medium-size trees or shrubs. They are mostly found in northern temperate climates. The leaves are simple and may be toothed or pointed. The fruit is a small samara, although the wings may be obscure in some species. The bark of all birches is characteristically marked with long historical lenticels and often separates into thin papery plates. The plant is practically imperishable because of the resinous oil that it contains. Its decided color gives the plant the common names Red, White, Black, Silver, and Yellow to different species. The buds of the tree form early and are full grown by midsummer. The branch is prolonged by the upper bud. The wood of all the species is close-grained and has a satiny texture that is capable of taking a fine polish. The leaves of the different species vary little. The flowers of the birch plant are monoecious, and open with or before the leaves. They are borne on three-flowered clusters. The staminate aments are pendulous, and clustered or solitary in the axils of the last leaves of the branch of the year. They form in early autumn and remain rigid during the winter. The Scales of the staminate aments are broadly ovate, rounded, and yellow or orange in color when mature. Each Scale has two bractlets and three sterile flowers. These Scales bear two or three fertile flowers. Each flower consists of a bare ovary. The ovary is compresed, two-celled, and grouped with two slender styles. The ovule is solitary. The ripenened pistillate ament bears tiny winged nuts, packed in the protecting curve of each brown and woody Scale. These nuts are pale chestnut brown and compressed. The seed fills the cavity of the nut. All of the birch species are easily grown from seed. Birch bark tea was used by Native Americans to relieve headaches. Some people also used this tea, which was made from the leaves and bark, for fevers and abdominal cramps. The properties that birch bark possesses allow it to help to heal burns and wound. It also is able to cleanse the blood. Birch bark also contains a glycoside that decomposes to methyl salicylate. This is a remedy for rheumatism that is used both in Canada and in the United States. A decoction of birch leaves is also recommended for baldness. Additionally, this herb works as a mild sedative for insomnia. The bark and leaves of the birch plant are used to provide anthelmintic, anti-inflammatory, anti-rheumatic, astringent, blood purifier, diaphoretic, diuretic, and stimulant properties. The primary nutrients found in this herb are calcium, chlorine, copper, fluoride, iron, magnesium, phosphorus, potassium, silicon, sodium, and vitamins A, C, E, B1, and B2. Primarily, birch is extremely beneficial in dealing with blood impurities, eczema, pain, rheumatism, and urinary problems. Additionally, this herb is very helpful in treating canker sores, cholera, diarrhea, dysentery, edema, fevers, gout, and bleeding gums. One should consult their health care provider before considering supplementing with any medications. This will insure that a person obtains the best results possible. For more information on the many benefits provided by birch, please feel free to consult a representative from your local health food store with more questions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2061) Nutritious Amaranth
Date:
April 09, 2009 03:08 PM
Amaranth is an herb full of vitamins. It was traditionally used by Native Americans in both Central and North America as a survival food. This herb has been cultivated for thousands of years in many different cultures due to the fact that it grows well in most climates and uses a very small amount of water. Amaranth contains a huge amount of protein and a lot more calcium than milk provides. It also contains the amino acid l-lysine, which is not often found in plants. Amaranth seeds were used by the Aztecs in their pagan ceremonies. Additionally, mature seeds of the amaranth plant were eaten raw, mixed with cornmeal, or added to soups. The leaves, which taste similar to spinach, can also be eaten. Often, amaranth is used for gastroenteritis or the stomach flu. It helps to lessen the irritability of the tissues. A strong decoction of amaranth can be used to remove worms and other parasites from the digestive tract. Applying amaranth topically can help to reduce tissue swelling. The herb can be used with bandages for medical treatment. Additionally, it can help stop excess bleeding which is often caused by sore gums, nosebleeds, and heavy menses. Amaranth is highly digestible and is recommended for infant formulas. Amaranth is a traditional food plant in Africa with the potential to improve nutrition greatly. There are several species of amaranth grown in Asia and the Americas for grain. Ancient grains still used to this day include three species: Amaranthus caudatus, Maranthus cruentus, and Amaranthus hypochondriacus. Even though amaranth was grown on a small Scale in parts of Mexico, Guatemala, Peru, India, and Nepal, there is a huge potential for future cultivation in the U.S. and tropical countries. Because of this, this herb is often referred to as “the crop of the future.” Because of a weedy life history, amaranth grains grow very rapidly, with their seedheads weighing up to 1 kilogram and containing a half-million seeds. Amaranthus species have a 30% higher protein value than rice, wheat flour, oats, rye and other cereals. Amaranth was revived in the 1970s because of it is very palatable, easy to cook, and a protein that is well suited to human nutritional needs. This herb was recovered in Mexico from wild varieties, now being commercially cultivated. A popular snack sold in Mexico City, this herb is often mixed with chocolate or puffed rice. Its use has recently spread to Europe and parts of North America. Amaranth is a pseudo grain because it has a very similar flavor and cooking ability to grains. Along with protein, amaranth provides a great source of dietary fiber and dietary minerals including iron, magnesium, phosphorus, copper, and manganese. The leaves, seeds, and flowers of the amaranth plant are responsible for all of the health benefitis provided. Amaranth’s properties include: alterative, astringent, demulcent, diuretic, and nutritive. Primarily, amaranth is used for diarrhea, dysentery, excessive menstruation, and nosebleeds. Amaranth can also be used for canker sores, bleeding gums, stomach and mouth ulcers, worms, and wounds. For more information on the benefits of this herb, please contact your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1990) Inositol And Choline
Date:
December 11, 2008 12:19 PM
Inositol is a member of the vitamin B complex family, being referred to as vitamin B8, but is not strictly a vitamin because it is biosynthesized in your body. Vitamins are essential substances that are not manufactured by your natural biochemistry, and must be taken in your diet. However, to all intents and purposes it works like a member of the vitamin B family. The main function of myo-inositol (the commonest isomer of inositol) is in the health of cell membranes, particularly those that comprise the marrow, eyes, intestines and the brain. Without proper regulation of the cell membrane, the cell cannot function effectively. Some of its effects include healthy hair and controlling estrogen levels. It is also believed to help to reduce cholesterol levels in the blood. A deficiency will result in hair loss, eczema, increased blood cholesterol levels and eye abnormalities. You might also suffer constipation, although this is not as serious a condition as those preceding. It is present at highest levels in the heart and brain, which indicates where it is mostly used, although it also helps the liver to break down fats and enables the nerves and muscles to operate as they should. Those that are depressed are frequently found to have low inositol levels in their spinal fluid, so it is believed to play a part in that condition. It is known that the substance takes part in the function of the neurotransmitter serotonin, which is known to play a part in depression, and initial signs are that its use in the treatment of depression could be effective. Neurotransmitters are responsible for passing messages across the gap (synapses) between nerve cells, their messages being decoded by the neuroreceptors. A healthy nervous system depends on healthy neurotransmitters. For these reasons, inositol has also been tried on other conditions of the nervous system. These include bipolar disorder, bulimia, panic disorder, obsessive compulsive disorder and attention deficit disorder. So far, results have been inconclusive as to its effectiveness, but it is early days yet and field tests are continuing. A test carried out in Beersheva, Israel, in 1997, found that treatment with inositol produced significant improvement in the depression of 28 patients after four weeks on the Hamilton Depression Scale1, and 21 patients tested with panic disorder (with and without agoraphobia) showed significant improvements in their condition, including agoraphobia. Results on 13 patients with obsessive compulsive disorder also showed significant improvement. These were all double-blind tests. However, not all tests have been so conclusive, and a study on 42 people with sever depression who did not respond to conventional antidepressant, also failed to respond when inositol was added to their medication.2 Results are therefore not conclusive. Four hundred people took part in a double-blind test that indicated a possible improvement in the symptoms of polycystic ovary syndrome when treated with inositol 3,4 and another that inositol treatment on patients taking lithium could help reduce the symptoms of psoriasis, a skin condition believed to be caused by a reaction of the immune system and nerves.5 The supplement has also been found to be just as effective as Luvox (fluvoxamine – similar to Prozac) after four weeks treatment. Although these results are good, they are inconclusive, and more data is need before any indisputable conclusions can be drawn. However, treatment with inositol might be worth considering if conventional treatment for these conditions has been unsuccessful. The most common natural form of inositol is myo-inositol, an isomer of cyclohehexanehexol, a carbocyclic polyol that form the structural basis for secondary messengers in the cells of eukaryotes. A secondary messenger system is one whereby a signaling molecule is released in response to a signal from a primary messenger such as a neuroreceptor, which then activates certain intracellular proteins known as effector proteins that exert a response from the cell. An example is cAMP (cyclic adenosine monophosphate) that is a secondary messenger that activates protein kinases and allows them to phosphorylated proteins. Eukaryotes are organisms that contain cells composed of complex components contained within a cellular membrane, and that also contain a nucleus. Examples are fungi, plants and all animals. Examples of non eukaryotes include the bacteria family. It is frequently recommended that inositol is most effective when taken with an equal amount of choline, although this might be due to the fact that when inositol deficiency is detected, choline is also frequently deficient. Both are vitamin B family like, and both are lipotropic, in that they aid the breakdown of fats in the body. It is not clear whether this is true or not, but taking both would certainly not harm you, and might be of great benefit. Inositol is not essential, because it can be obtained from beans, nuts, seeds, whole grains, cantaloupe, brewer’s yeast, liver and vegetables. Bacteria in the gut also act on the phytic acid (inositol hexaphosphate) contained in citrus fruits to form inositol. However, be careful if you drink a lot of coffee. It destroys inositol, and if you are taking the supplement medicinally, steer clear of coffee during your period of treatment because it will lose its effect. Excessive coffee drinking can also result in a general depletion of inositol from your diet, and hence a deficiency. In such a case you are advised to take a supplement, preferably along with choline that might also be deficient. Although there have been no adverse side effects reported, no specific longer term safety studies have been carried out on inositol. Because of the way it works, inositol should be avoided by people with liver or kidney disease, and also by expectant or nursing women. It should be avoided by young children until safety tests have been carried out, and it is believed that it can cause manic effects in those suffering bipolar disorder. Other than for these specific cases, trials with many times the average daily intake of the substance, it currently appears safe to take inositol as a long-term supplement. However, as with all such supplements intended for specific disorders, you should seek the advice of your physician. References: 1. Levine J: Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev,Beersheva, Israel ur Neuropsychopharmacol, 1997 May, 7:2, 147-55 2. Nemets B, Mishory A, Levine J, et al. Inositol addition does not improve depression in SSRI treatment failures. J Neural Transm. 1999;106:795-798. 3. Gerli S, Mignosa M, Di Renzo GC. Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2003;7:151-9. 4. Gerli S, Papaleo E, Ferrari A, et al. Randomized, double-blind, placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS. Eur Rev Med Pharmacol Sci. 2007;11:347-354.
5. Allan SJ, Kavanagh GM, Herd RM, et al. The effect of inositol supplements on the psoriasis of patients taking lithium: arandomized, placebo-controlled trial. Br J Dermatol. 2004;150:966-969.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1948) Pinolenic Acid - Appetite Control
Date:
April 25, 2008 02:50 PM
Mention "pine nuts" and peoples’ mouths are apt to start watering for a taste of garlicky pesto or fragrant pilaf. Ironically, the same ingredient that is so irresistible in gourmet cooking may help curb our out-of-control appetites. But only a particular variety of pine nut—Pinus koraiensis from Korea—will do. Source Naturals PineSlim is a Korean pine nut oil (PinnoThin™). A small-Scale study suggests that PineSlim may reduce feelings of hunger by increasing concentrations of appetite-suppressing hormones. The study also suggests that a feeling of fullness is experienced 30-60 minutes after taking PineSlim. For best results, PineSlim should be taken while following the Maximum Metabolism Weight Loss Plan™ enclosed in every bottle. Enjoying good food is part of a healthy lifestyle, but too often we don’t know when to stop. PineSlim can help by addressing one of the most basic of the dozen deep metabolic systems identified by Source Naturals as critical to your optimal health: Hormones/Metabolism. Less Calories for Improved Health According to a National Health and Nutrition Examination Survey, an estimated 66% of U.S. adults are overweight. A normal body fat level is one of the factors associated with many markers of good health, including insulin efficiency, healthy inflammation response, good circulation, and normal cell regeneration. One of the best ways to achieve healthy weight is by curbing the amount of calories we take in—but that’s not always easy to do. Now an ancient Asian food source may help. Korean Pine Nuts—Traditional Asian Food The Korean pine nut (Pinus koraiensis) has been used as a food source for centuries and is often served as a snack at social events in China. Korean pine nuts grow on evergreen trees that produce seeds (commonly referred to as nuts) that are rich in oil, particularly oleic, linoleic, and pinolenic acids. Pinolenic acid is a fatty acid, which may influence healthy blood pressure. According to recent research, pinolenic acid also may increase concentrations of the satiety hormones glucogon-like peptide-1 (GLP- 1) and cholecystokinin (CCK). Appetite-Suppressing Hormones Both GLP-1 and CCK are hormones that have been found to increase satiety and suppress appetite in normal-weight humans. They are believed to work by delaying gastric emptying. Retaining food in the stomach for a longer period of time may prolong a feeling of fullness. In a randomized, double-blind trial, 18 overweight women received 3.00 grams of Korean pine nut oil (PinnoThin™)—the same amount as one daily dose of Pine Slim—or an olive oil placebo before a carbohydrate meal. Hormone measures of CCK and GLP-1 were taken from blood samples, and subjective measures of appetite were recorded. The study demonstrated a significant increase in appetite-suppressing CCK and GLP-1 hormones at 30-60 minutes after supplementation. Your Source for Advanced Nutrition The plant world offers an abundance of health promoting compounds. Today exciting discoveries are emerging from research into the health benefits of botanicals. The development of PineSlim reflects Source Naturals’ commitment to manufacturing supplements on the cutting edge of nutritional science. We are glad to partner with your local health food store in bringing you nutritional resources that help you take charge of your health. References: Causey JL (3/28/06) Korean Pine Nut Fatty Acids Induce Satiety-producing Hormone Release in Overweight Human Volunteers, American Chemical Society Abstract, “Health Benefits of Lipids” Symposium. ABSTRACT 0117: TECH-3. Fontana L. (2006) Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 295(13): 1577-1578. Masoro EJ. (2005) Overview of caloric restriction and ageing. Mech Ageing Dev. 126: 913-922. Sugano M, Ikeda I, Wakamatse K, Oka T. (1994) Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. British Journal of Nutrition. 72:775-783.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1773) Lutein - A plant pigment provides sun protection from the inside out.
Date:
July 09, 2007 01:21 PM
A plant pigment provides sun protection from the inside out. Energy on earth begins with the sun’s rays, which spark the photosynthesis in plants that ultimately powers all life. (Petroleum is the residue of prehistoric plants crushed over eons into liquid form.) But the sun’s energy is not totally benign for us humans; excess exposure can cause skin to wrinkle and eyesight to dim. Enter lutein. This plant chemical, reddish-orange like the setting sun, has become a hot commodity over the past several years because of its ability to protect both eyes and skin against sun damage. A member of the carotenoid family of nutrients, lutein is generally paired with its partner, Zeaxanthin, in a wide variety of foods, including egg yolks, fruits, corn and leafy greens such as spinach (where its bright color is masked by the green of chlorophyll). That’s a good thing, since your body can’t make lutein and so needs to obtain it from your diet. Skin Shield The sun produces a whole spectrum of light rays, from the visible (red through violet) to the invisible or ultraviolet (UV). UV rays—both ultraviolet-A (UVA) and ultraviolet-B (UVB)—are troublemakers. They attack collagen, the protein that gives skin its shape, which leads to wrinkles and other signs of aging. What’s worse, UV is also capable of damaging skin cell DNA, a process that can promote cancer development. And UV isn’t the only culprit: The sun’s visible blue rays are believed to help create harmful molecules called free radicals within the skin. The clue to lutein’s importance in fending off skin damage lies in the fact that it is found throughout both the outer (epidermis) and inner (dermis) skin layers, where as an antioxidant it fights free radicals and as an orange pigment it soaks up blue light. In one study, using lutein both orally and topically produced improvements in skin hydration and suppleness (Skin Pharmacology and Physiology 4/19/07). Lutein has also shown an ability to counter the inflammation and immune system suppression associated with excess UV exposure (Journal of Investigative Dermatology 2/04). Lutein Gleanings What is it? A red orange carotenoid found in a number of fruits and vegetables, generally with a similar compound called Zeaxanthin. What does it do? This powerful antioxidant helps protect the eyes against both cataracts and age-related macular degeneration (AMD); it also appears to defend the skin against sun damage and has been associated with reduced arterial wall thickness, a measure of cardiovascular health. The Eyes Have It Your eyes, like your skin, are directly exposed to the sun’s UV rays. Such exposure can cloud the eye’s lens to create cataracts. It can also disrupt the retina at the back of the eye particularly the macula, the part of the retina responsible for clear central vision—which can result in age-related macular degeneration. Not surprisingly, the eye is yet another one of the body’s lutein hot spots. This pigment is especially concentrated in the macula; in fact, of the 600 or so carotenoids that exist in nature, only lutein and Zeaxanthin are found within this all important structure. So it also isn’t surprising to learn that they Eye Disease Case Control Study, one of the first large-Scale investigations into carotenoids and eye health, found a link between reduced AMD risk and high levels of lutein and Zeaxanthin. Current research has focused on the use of supplemental lutein in AMD patients, with promising results. It isn’t only the outside of your body that may benefit from lutein. When oxidized by free radicals, LDL cholesterol settles into arterial walls. Lutein may help slow this process; in one study, people with the most lutein in their blood had 80% less vessel-wall thickening than those with the least (circulation 6/19/01). So enjoy some fun in the sun. But respect the power of those golden rays, and let lutein help make playtime a safe time. –Lisa James.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1584) Neurological Health and CoQ10
Date:
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases. Q. What is CoQ10? A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body. Q. Isn’t CoQ10 a supplement for heart health? A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage. Q. How does CoQ10 affect brain health? A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production. The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced. The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced. Q. What is the blood-brain barrier and why is it important? A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree. Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle. Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier. Q. If CoQ10 is made in the body, why take supplements? A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body. Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10. Q. How does CoQ10 help people with Parkinson’s disease? A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration. A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This Scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment. Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months. The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10. The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease. Q. What were the results of clinical research on Huntington’s Disease? A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease. Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness. Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10. Q. What other diseases could benefit from CoQ10 supplementation? A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s. In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health. ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation. Q. Can taking CoQ10 prevent neurodegenerative disease? A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases. Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection. Q. How much CoQ10 should I take? A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day. CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect. Q. What should I look for in a CoQ10 supplement? A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor. Conclusion CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body. All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459) New Study Promotes “Omega-3 Index”…
Date:
September 12, 2006 02:16 PM
A large scientific review has concluded that omega-3 fatty acids are indeed beneficial to heart health—so much so that if warrants a new measure of cardiovascular risk, which the authors suggest should be called the “Omega-3 Index.” Published online in the journal Cardiovascular Research (dol: 10.1016/J.Cardiores.2006.08.019), researchers reviewed epidemiological and four large-Scale intervention studies and concluded that majority of evidence supports the beneficial activity of omega-3s. The mechanism behind the benefits, as proposed by the authors, is the incorporation of EPA and DHA, two types of omega-3s, into cell membranes, which replace other fatty acids and change the properties of the cell. The “Omega-3 Index” would be defined as the percentage of EPA plus DHA in red blood cell membranes, relative to other fatty acids. Based on data from the literature, the authors assessed that an omega-3 index value of eight percent or above is associated with a 90 percent reduction in the risk of sudden cardiac death.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1378) Remifemin symptomatic relief, scientifically supported*
Date:
August 26, 2006 02:41 PM
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1358) Cayenne pepper is a very hot ground spice
Date:
February 01, 2006 11:30 AM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1200) Omega-3’s Fight Postpartum depression
Date:
January 23, 2006 02:42 PM
Omega-3’s Fight Postpartum depression Tucson, AZ—Marine-sourced omega-3 essential fatty acids (N-3 EFAs) combat postpartum depression (PPD), according to a study published online in acta Psychiatrica Scandinavia (www.blackwell-synergy.com). In the eight-week trial, test subjects were randomized to receive 0.5 g/d (n-6), 1.4 g/d (N-3) or 2.8 g/d (n-7) n-3 EFAs (as EPAX omega-3 oil provided by Epax AS, Previously a division of Pronova Biocare AS [www.provona.com]). All groups had reductions in mean scores on Edinburgh Postnatal and Hamilton Rating depression Scales (51.5 percent and 48.8 percent, respectively); changes from baseline were significant within each group and when combining groups. The researchers concluded results of the study support further study of n-3 fatty acids as a treatment for PPD. “Omega-3 fatty acids were assessed in a double-blind dose-ranging trial,” said Marlene Freeman, M.D., director of the Women’s Mental Health Program and assistant professor of Psychiatry, Obstetrics & Gynecology, and Nutritional Sciences at the University of Arizona College of Medicine. “A combination of omega-3 EPA and DHA fatty acids provided by EPAX AS was utilized. Among all three doses, patients with postpartum depression improved substantially during the trial. Scores on depression measures decreased by approximately 50 percent and differences were statistically significant.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1192) Thyroid Health
Date:
January 05, 2006 10:29 AM
Fact: Millions of Americans trying to lose weight are horrified to see their bathroom Scales inching uncontrollably upwards. And these numbers increase every single year. Making matters worse, many of these same people are shocked to find their energy levels slipping inexorably downwards. I guess I’ve just got a slow metabolism…” “You can’t get as much done when you start getting older…” “Why am I always so cold?” Sound a little too familiar? What if there was a safe and natural way to energize your metabolism and keep it operating at its youthful, maximum efficiency? While it is true that metabolism slows somewhat with age, its not inevitable that every one of us is destined to end up with more weight to move around and less energy to get there. There are people in their 30’s, 40’s, 50’s, 60’s and beyond with all the vibrant energy they need. There are people who end every day with a list of important accomplishments completed. So what’s their secret? It may well be a healthy, fully functioning thyroid.The human thyroid is a butterfly-shaped gland located in the front of the neck that wraps around the trachea. It has but one job - to produce the two critical thyroid hormones we need to keep our metabolism efficient. In fact, these hormones are indispensable for our bodies to convert calories into energy – and that’s the crux of metabolism. These two hormones, triiodothyronine and thyroxine, or T3 and T4 respectively, are produced in the thyroid when the iodine in our system teams up with the amino acid L-tyrosine. Sounds simple, right? Think again. Human metabolism is a highly intricate process that can be adversely affected by a wealth of variables. One important variable that we can control, is the nutrient mix our thyroid keeps on hand to operate. In order for metabolism to occur with any respectable level of effectiveness, the body must have a full supply of thyroid supporting nutrients on hand at all times. If you aren’t willing to deliver the nutrients it needs to function properly, chances are, it won’t be able to do what it’s supposed to (which is to keep your metabolism fired up and your energy resources fully charged).Don’t despair. There is good news. Encouraging and maintaining healthy thyroid function may be easier than you might imagine. This master gland of metabolism is often very responsive to the right combination of thyroid supporting nutrients. Yes, a healthy diet will promote a healthy thyroid, but some of the nutrients that are especially helpful in supporting healthy thyroid function are not likely to be found in your local market. That is, unless you happen to be shopping in India or Ireland. So just what are the critical nutrients for a healthy, energized thyroid? L-Tyrosine. This amino acid plays an essential role in the production of thyroid hormones, in addition to hormones that affect mood including epinephrine, norepinephrine, serotonin, and dopamine. And while our body can naturally produce some Tyrosine from other amino acids, as we age, our bodies may not be able to keep up with the needs of a demanding thyroid. During metabolism, tyrosine joins forces with iodine in order to produce the thyroid hormones needed to efficiently convert (metabolize) the calories from our diet into expendable energy. A weak reserve of tyrosine can leave us feeling sluggish. As a result, our body reacts by storing more calories as fat for energy. Iodine. Another key player in the metabolism game. Without it, metabolism simply can not take place. The thyroid is the only gland in the human body capable of absorbing this trace element. Typically found in shellfish and iodized salts, iodine is stored in the thyroid gland until needed for the production of the thyroid hormones triiodothyronine and thyroxine. When combined with L-tyrosine and other nutrients these two work synergistically to produce T3 and T4 thyroid hormone. Moreover, iodine deficiencies have been linked to the formation of goiters, decreased energy and lack of concentration. Irish Moss. A natural vegetarian source of many thyroid-supporting nutrients, including Iodine, a key component in healthy metabolism. Irish moss has been consumed for thousands of years, and many herbalists encourage its use to contribute to sound glandular health. Selenium. This naturally occuring trace mineral is well known for its strong antioxidant properties and natural synergism with other vitamins. Supplementing with selenium is essential for anyone concerned with sluggish thyroid performance. Guggul. Technically known as Guggulsterone, the Gug¬gul tree is native to India, and emits a resinous sap that has been used for centuries as part of India’s traditional medicine known as Ayurveda. Studies have shown that the purified plant sterol extract from Guggulsterone can promote healthy thyroid function, and assist the body in maintaining normal production of thyroxine and triiodo¬thyronine. Simply put, the thyroid gland relies heavily on a host supporting nutrients to produce the hormones needed to ensure that metabolism goes off without a hitch. Without these vital nutrients, our ability to metabolize food may slow down. Here’s an easy way to remember how this process works. The less thyroid supporting nutrients we have, the less thyroid hormone (T3 and T4) we produce. The less thyroid hormone we produce, the less efficient our metabolic process becomes. The less effective our metabolic process becomes, the less energy we produce. The less energy we produce, the more prone we are to weight gain and fatigue. NOW® Thyroid Energy was scientifically formulated to help maintain healthy thyroid function by incorporating a powerful blend of thyroid sup¬porting nutrients. With a full gram of L-Tyrosine (the direct precursor to thyroid hormone production) in addition to Iodine from Kelp, Selenium, Guggul, Zinc, Copper and a perfectly balanced blend of B vitamins, NOW® Thyroid energy just may be the boost you’ve been looking for.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1164) The Free Radical Theory
Date:
December 14, 2005 12:11 PM
The popular theory has been the subject of a great deal of research. Developed by Denham Harman, M.D., Ph.D., at the University of Nebraska in 1956, the free radical theory proposes that unstable molecules known as free radicals are responsible for inflicting extensive cellular damage, which causes cell death and dysfunction and eventually, disease. The most common type of free radicals are oxygen derived, and free radical damage is often referred to as oxidation. Environmental sources of free radicals include radiation (I.E., sun exposure, X-rays), ozone and nitrous oxide, heavy metals (i.e., mercury, cadmium, lead), smoke, alcohol, saturated fat, and other chemicals and pollutants. The body itself generates free radicals in performing essential bodily functions including energy production and immune activities. Fortunately, the body also has the ability to create antioxidants to neutralize the free radicals and prevent extensive cellular damage. When free radicals are not neutralized by antioxidants, they inflict large-Scale cellular damage which can cascade and lead to age-related degenerative diseases such as osteoarthritis, osteoporosis and age –relaged macular degeneration. For example, free radical damage to joint cells may cause the cartilage to become rough or break down, and can lead to the development of osteoarthritis. Antioxidants are needed to comb at free radicals and prevent this cellular damage. “Oxidative stress can lead to DNA mutations, cell death, and disease, all of which contribute to aging,” said Gerald R. Cysewski, president and chief executive officer (CEO) at Cyanotech corp. “Antioxidants are produced naturally by the body to combat oxidative stress by neutralizing free radicals. Increasing the amount of antioxidants in one’s system by consumption of supplements can provide further protection from the damaging effects of free radicals.” Because the body is continually assaulted by free radicals, antioxidant supplementation is often necessary. “by taking certain nutrients that our bodies stop producing over time, supplements help us to maintain a youthful look and health, which in turn enhances the quality of life,” Alkayali said. “Furthermore, supplements can help decrease oxidative stress that may otherwise accompany age-related illness and disease.” Many Substances are known antioxidants including certain enzymes, vitamins, phytochemicals and minerals, and include Vitamin C, Vitamin E, alpha-lipoic acid, coenzyme Q10 (CoQ10), Carotenoids, Selenium, superoxide dismutase, melatonin, quercetin, catechins, and zinc. Consuming a diet high in plant sources of powerful antioxidants is an important step to deter ageing, because nutrients from foods are often highly bioavailable and can act synergistically to increase their health benefits. Garlic contains several antioxidant phytochemicals and minerals including allicin, beta-carotene, quercetin, selenium and zinc, and may have a protective effect against stomach and colorectal cancers. Catechins are potent antioxidants flavonoids, with the best known source being green tea; they include gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC) and epigallocatechin gallate (EGCG). These antioxidants are being studied for their powerful abilities to combat free radical damage. In particular, EGCG has been researched for its reported protection against certain cancers and Alzheimer’s disease. Green Foods such as seaweed, sea vegetables, young grain grasses and shoots, broccoli, cabbage and other green leafy vegetables pack a nutritional punch due to their concentratged amounts of antioxidant carotenoids, vitamins and the enzyme superoxide dismutase (SOD). SOD is produced by the body and neutralizes free radicals known as superoxide radicals, which cause damaging fat oxidation. GliSODin is a patented form of SOD derived from cantaloupe and bound to a wheat protein for superior bioavailability. “GliSODin promotes the body’s production of its own endogenous antioxidants, including SOD, catalase and glutathione peroxidase, in virtually every cell,” said Eric Anderson, brand manager at P.L. Thomas. “This activation of the cellular antioxidant defenses across the whole body creates a state of alertness against any shock of oxidative stress, including sun rays, to which our body may be exposed.” Pomegranates contain two powerful antioxidants—ellagic acid, derived from fruit’s seeds, and punicaligans, found in the juice. “Research has shown that the juice from the pomegranate, rich in polyphenols, reduces oxidative stress by helping to produce enzymes to fight free radicals,” Alkayali said. NeoCell Corp. manufactures of ellagic-acid based Pomegranate Power, while P.L. Thomas supplies POM40p, a kosher-free pomegranate juice extract standardized to 40-precent punicocides, polyphenols belong to the punicalagin family. Consumer demand is on the rise for products that address degenerative health conditions, including supplements that support function of the bones, joints, eyes. According to a June 2005 report by the freedonia group, “Bone and joint care products will continue to dominate the health maintenance segment, spurred by a growing customer base and a plethora of new and improved products expected to soon enter the marketplace.” The report also projected rapid gains for vision care. “Demand for vision care products will be propelled by aging baby boomers who are becoming aware of debilitating eye conditions and seeking both preventive measures and ameliorative treatments.” Dietary Supplements can help prevent and ease symptoms of age-related diseases affecting the joints, bones and eyes, including osteoarthritis, osteoporosis and age-related macular degeneration (AMD).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1013) All SAM-e supplements are not created equal
Date:
October 26, 2005 12:41 PM
All SAM-e supplements are not created equal During the manufacture of SAM-e, two forms are produced known as the S,S and the R,S isomers. The S,S isomer is the biologically active form in the human body, whereas the R,S form is considered to be inactive. Double Strength SAMe 400 utilizes Italian SAM-e to yield the highest available percentage of the active pure S,S form on the market. Double Strength SAMe 400 contains an average of nearly 80% of the active S,S form. Other SAM-e products contain as little as only 50% of the active form. A higher content of the active form yields a more potent product. The molecule SAM-e itself is highly unstable. It will degrade quickly in conditions of heat, light and moisture. To increase its stability, it must be formed into a salt. It is important to note that SAM-e used for dietary supplements exists in a number of salt forms. Double Strength SAMe 400 utilizes the SAM-e tosylate disulfate salt form. This salt has been the most extensively utilized form in clinical trials of SAM-e. Because of the unstable nature of pure SAM-e it is also highly susceptible to degradation in an acidic environment like the stomach. To be utilized effectively, it must pass through the stomach for absorption in the small intestine. For this reason, only enteric-coated formulas should be used. Double Strength SAMe 400 tablets are enteric-coated to maximize the utilization and benefit of the SAM-e by the body.
BenefitsEnhances Mood and Neural Function* SAM-e has been studied for decades now for its potential role in enhancing mood and supporting healthy neural metabolism. In a double-blind placebo trial published in 1976, 30 individuals were given either SAM-e intramuscular injections (15 mg three times daily) or placebo. Individuals were assessed for improved mood and affect. It was found that 100% of patients in the SAMe group showed significant improvements in mood, while only 30% of the placebo group showed any improvement.1 The improvement seen with SAM-e in this trial was rapid, with a response time of between 4 and 7 days. A second Italian double-blind placebo controlled study was published in 1987. Again, individuals showing signs of decreased affect and mood were administered 200 mg SAM-e as daily intramuscular injections, or a placebo, for four weeks. Each group consisted of 20 patients, with all medial and laboratory results being normal. Rating Scales were used to monitor changes and the authors found that the treatment with SAM-e was significantly superior to placebo and was very well tolerated.2 Researchers had known that SAM-e injections showed benefit in mood enhancement based on the results of multiple clinical trials. However, with injections, chronic administration is always challenging. For this reason, oral doses are superior in terms of ease of administration. Studies were conducted to assess the efficacy of oral SAM-e preparations. One such study was published in 1990. In this double-blind placebo-controlled trial, individuals were given increasing doses of SAM-e from 200 mg to 800 mg twice daily, or placebo, over the 21 day period of the trial. In the placebo group, one of the six individuals showed an enhancement of mood of 50% according to the rating Scales, whereas 6 of the 9 individuals given the oral SAM-e showed a 50% or greater improvement in mood and affect.3 It was concluded that oral SAM-e, like SAM-e injections, can significantly enhance mood without significant side effects. Another double-blind placebo controlled trial looked at the effects of administering 1600 mg of SAM-e, or placebo, daily to 80 women aged between 45 and 59. The administration took place for 30 days, after which the women were assessed for improvements. Rating Scales were administered at 10 and 30 days. SAM-e supplementation significantly enhanced mood and affect in the women compared to placebo administration.4 SAM-e was also seen to be well tolerated, as three women in the placebo group and two women in the SAM-e group complained of minor side effects which did not interfere with continuation of treatment.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=899) Folic acid enhances Chemotherapy
Date:
October 10, 2005 12:05 PM
Folic acid enhances Chemotherapy Scientists have discovered that cancer cells have a natural attraction to folic acid. This safe constituent of vitamin B is now being used as a nontoxic “Trojan horse” to carry chemotherapy directly to various cancers. Researchers reported at the 4th annual Gene, Drug Therapy and Molecular Biology meeting that the vitamin can be used with conventional chemotherapy drugs and a variety of new gene therapies to destroy cancer cells. Scientists have repeatedly found that folic acid is overexpressed in certain cancers: specifically, cancers of the ovary, cervix, endometrium, kidney, breast, brain, lung and colon. Scientists found that folic acid is especially overexpressed on tumors that are resistant to conventional chemotherapy. Dr. Philip Low of Purdue University and chief scientific officer at Endocyte, Inc. based in Lafayette, Indiana, told attendees that folic acid could become a perfect carrier for many types of tumor targeting. Endocyte researchers estimate that cancers that overexpress the folate receptor are diagnosed in about 300,000 people each year in the US. This new specific targeting approach exploits cancer cells' insatiable appetite for folic acid. Compared to healthy cells, researchers say that cancer cells have 500,000 times greater affinity for folic acid. The folic acid that these cells ravenously seek can be used to target and deliver drugs to easy-to-find and hard-toreach cancer cells at the same time while avoiding normal, healthy cells. Folic acid does not trigger an immune response in the human body. It is readily available, easy to produce on large Scale, and can be attached to a great number of drugs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=829) Guys should forget the six-pack abs and just lose the beer belly.
Date:
September 24, 2005 12:00 PM
Time for a Gut Check Guys should forget the six-pack abs and just lose the beer belly. When a woman noticed her husband standing on the bathroom Scale and sucking in his stomach, she said, “I don’t think that’s going to help.” “Sure it will,” he responded. “It’s the only way I can see the numbers.” Funny line, sure. But whether you’re talking about “love handles,” a “spare tire” or the proverbial “beer belly,” having a tummy that hangs over your belt buckle is no laughing matter. It’s not even a matter of the quest for “six-pack abs” or a “washboard stomach.” It’s a matter of health. Consider this: A recent study appearing in the American Journal of Clinical Nutrition showed that a man’s waist size can be a good predictor for the development of type 2 diabetes. A Harvard Health Professionals team, led by Dr. Youfa Wang, an assistant professor at the John Hopkins University Bloomberg School of Public Health, analyzed data from more than 27,000 men who were tracked for more than 13 years. The team found that men with larger waists or a higher body mass index (BMI) were both at greater risk for type 2 diabetes than slimmer men. (You find your body mass index by dividing your weight in kilograms by the square of your height in meters. If your waist size is 40 inches or less, a BMI of 25 or over means you’re overweight.) “Abdominal fat measured by waist circumference can indicate a strong diabetes risk, whether or not a man is considered overweight or obese according to his BMI,” says Wang. The Harvard team found that men with waist sizes of 40 to 62 inches were 12 times more likely to develop diabetes and suggested that the current recommended waistline of 40 inches or below for men may need to be lowered. Flatten Up Okay, now that we’ve scared the bejeezes out of all you guys under 6-foot-4 who by your pants in the big-man store, let’s talk about what you have to do to shop anywhere in the mall. Again, this is not about looking like a Greek ab god. This is about diminishing your risk for a myriad of health problems and being able to comfortably bend over for a ground ball during the pickup softball game. And there are no shortcuts, so forget about liposuctioning those years of accumulated lard. Despite what all those TV makeover shows say, liposuction can only really enhance your body aesthetic if you lose a large chunk of the surface fat first. “Those makeover shows have it all backwards,” says Dr. Bruce Nadler, a fitness trainer who also happens to be a plastic surgeon. “They do surgery on someone’s midsection and then have them doing intense workouts when they are supposed to be recuperating from surgery. I wouldn’t do liposuction until you see what diet and exercise can accomplish. When you have all the weight in the midsection the dangerous fat is deep within the body. So liposuction may make you look better but it won’t necessarily improve your health.” The Gut Check Plan Talk to any exercise expert worth their weight in body fat, including Nadler, and they will tell you that on of the biggest fitness fallacies is the notion that intense abdominal workouts and use of abdominal machines (like those sold through those interminable infomercials) are the keys to getting a flatter and more “ripped” midsection. In fact, for many people it’s not physiologically possible to achieve a flat tummy because abdominals are not designed to be flat. And the idea of “spot reduction,” exercising the area where you want to lose the fat, is now considered a myth. Research has shown that fat is lost all over your body, not just in the area that you work. It’s not that you can’t benefit from doing abdominal exercises. Crunches, situps and leg raises, when done properly, are great for muscle tone and endurance (and you do burn calories), but the real key to achieving a wonderful waist size is losing body fat. How do you do that? “Dropping a few inches from your midsection,” says Nadler, “depends on four things- calorie reduction through proper diet (eating very little fat, consuming complex carbohydrates and doing it all in smaller portions), stepping up aerobic activity (such as running an bicycling, which burns excess calories quickly and safely), and resistance weight training (which not only increases metabolism and helps burn more excess calories, but also builds and strengthens the abdominal wall).” Then, adds Nadler, when you’ve just about reached your waist=reduction goal, but genetics still won’t give you a flatter stomach, “that’s where plastic surgery may come in as icing on the cake.” Nadler also advises men not to panic if they don’t notice a substantial weight reduction during a training program. “When people are doing weight and resistance training they are too hung up on the Scale,” insists Nadler. “Muscle weighs more than fat so don’t judge your progress by what you weigh, but on what your percentage of body fat is. That’s the number you want to see going down.”
So how long does it take for men with an oversized gut to lose the excess? “Depending on how much they have to lose,” Nadler says, “it takes anywhere from three to six months.” By the way, for men in their 30s and up, there are also two important side benefits to decreasing the waist size and firming up the gut: better overall posture and diminishing the potential for chronic back pain. So get to work guys; suck it up so you can stop sucking it in. -Stephen Hanks
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=796) PepZin GI™ helps relieve occasional discomfort.
Date:
September 20, 2005 05:40 PM
PepZin GI™ helps relieve occasional discomfort.* CLINICAL TRIALS In a randomized, multi-center, placebo-controlled double blind study, 299 patients suffering with symptoms of gastric discomfort were randomly allocated to receive either a zinc-L-carnosine complex or a placebo, or a control drug or its placebo for 8 weeks. Improvement ratings for a range of symptoms were taken at various points during the trial and compared with before treatment data. Of the 258 people who completed the trial, 136 were in the zinc-Lcarnosine group. Of the group, 92% of the participants were rated as “moderately improved” or better on an improvement Scale across the category of symptoms including heartburn, tenderness, epigastric pain, diarrhea and constipation after 8 weeks.3 In another study, 28 patients with gastric discomfort were given a zinc-L-carnosine compound and monitored for 8 weeks. Improvement was rated on a Scale of subjective and objective symptoms. After 4 weeks, the rate of those cases that were considered to be “significantly improved” was 68.4%. After eight weeks, the “significantly improved” number was 68.8%. Over 60% of these patients remained in the “significantly improved” category well after discontinuation of the treatment, suggesting a lasting effect of the zinc-L-carnosine compound beyond the time it is taken.4 Maintains a healthy GI environment.* The mineral zinc in PepZin GI™ is a critical component to a number of physiological processes in our bodies. Some of these functions include growth and metabolism of cells, healing of wounds,and maintenance of carbohydrate and lipid metabolism.2 PepZin GI™ may also be able to favorably maintain the bacterial balance of the stomach and GI tract. Studies suggest that the zinc-L-carnosine co m pound may have effects on certain strains of harmful bacteria and, therefore, may be able to help maintain a GI environment that is favorable to health.1 By supporting the bacterial balance in the stomach, PepZin GI™ can help maintain a healthy mucosal lining. Supports the health of gastric cells.* PepZin GI™ has been studied for its ability to prevent free radical damage to gastric cells. In one such study, rat gastric cells were exposed to ethanol and hydrogen peroxide, two substances known to cause free radical damage to living cells. Cells were bathed in hydrogen peroxide, ethanol, zinc-L-carnosine, or a combination of zinc-L-carnosine with either ethanol or hydrogen peroxide. While the cells bathed in ethanol and hydrogen peroxide solutions all exhibited signs of damage due to free radical production, the cells that were bathed in zinc-L-carnosine were largely protected from the effects of free radical damage. The authors concluded that the zinc compound directly protected gastric mucosal cells from oxidant stress and alcohol induced damage.5 Additional research further confirms the gastro-protective effects of PepZin GI™. In another rat study, stomach lesions were induced by administration of the chemical monochloramine, a known pro-oxidant (producer of free radicals). One of the groups of rats was fed the zinc-Lcarnosine compound prior to being exposed to monochloramine. The researchers found that the size of the lesions in the group pre-treated with zinc-L-carnosine was significantly less than the lesions in the control group. The authors concluded that the zinc compound exerted a beneficial protective effect against monochloramine-induced stomach lesions.6 The zinc-L-carnosine in PepZin GI™ has also been shown to slow the development of aspirin induced stomach damage in rats. The researchers measurably detected lower levels of TNF-alpha in rats given zinc-L-carnosine as compared to the control rats. TNF-alpha is an inflammatory cytokine that is known to be released in response to gastric damage.7 These results may suggest a role for PepZin GI™ in protecting gastric cells by occasionally reducing the levels of certain cytokines in minor inflammation of the stomach. Scientific References 1. Kuwayama H, et al. Polaprezinc. Nippon Rinsho 2002 Feb; 60 Suppl 2:717-720. 2.Matsukura T,Tanaka H. Applicability of zinc complex of l-carnosine for medical use. Biochemistry (Moscow) 2000;65(7):817-823. 3.Miyoshi A, et al. Clinical evaluation of Z-103 on gastric ulcer - a multicenter double-blind comparative study with cetraxate hydrochloride. Jpn PharmTher 1992;20(1):199-223. 4.Misawa T, et al. Clinical study of Z-103 - clinical effects on gastric ulcer and influence on endocrine function. Jpn PharmTher 1992; 20(1):245-254. 5. Hiraishi H, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacl Ther 1999;13:261-269. 6. Kato S, Nishiwaki H, et al. Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Dig Dis Sci 1997;42(10):2156-2163. 7.Naito Y, et al. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci 2001;46(4):845-851.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=792) The Role of Naturally Occurring Progesterone in the Body
Date:
July 25, 2005 09:50 PM
The Role of Naturally Occurring Progesterone in the Body In light of the previous section, it is vital to keep in mind that when progesterone is produced and maintained, most of the negative side effects of estrogen are neutralized. Unfortunately, in far too many women, progesterone levels fail to do the job. Let’s discuss exactly what progesterone is responsible for. A woman’s ovaries produce two key hormones: estrogen and progesterone during her ovulatory years. The corpus luteum makes progesterone just before ovulation which rapidly escalates during the two week period following ovulation. The primary task of progesterone is to support implantation and sustain pregnancy. It does this by inhibiting uterine contraction and by suppressing the immune system’s response to the developing embryo as a foreign body.2 During the last two weeks of a woman’s menstrual cycle, progesterone is considered the dominant female hormone. During pregnancy, the placenta takes over the task of progesterone synthesis. Progesterone is also made in limited amounts in the adrenal glands of both men and women and in the testes of the male. PROGESTERONE SECRETION RATES The following breakdown gives general guidelines of amounts and time of progesterone secretion: Approximately twelve days following ovulation, if fertilization has not occurred, progesterone levels decline rapidly, which initiates the shedding of the uterine lining, also known as menstruation. In time, progesterone is transported through the bloodstream to the liver where it is metabolized and excreted as waste through the kidneys (urine) and the bile. Typically, pregnancy tests are reacting to increased levels of HCG or of progesterone in the urine, indicating that pregnancy has occurred. (Note: What is crucial to remember is that a woman’s cycle, regardless of her age, may not be characterized by the above Scale. A number of factors may cause estrogen to remain dominant, even after progesterone is supposed to take over in the latter half of the cycle. Even young women who suffer from nutritional deficiencies, stress, etc. may experience an estrogen dominance, suggesting the need for natural progesterone supplementation.) THE THREE-FOLD ACTION OF PROGESTERONE 1. It ensures the implantation and development of a fertilized egg and subsequent embryo and fetus. 2. It acts as a precursor to other steroid hormones such as cortisone which is produced in the adrenal glands and contributes to the production of the sex hormones including testosterone. 3. It exerts a number of desirable physiological actions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=656) RECENT RESEARCH
Date:
July 15, 2005 09:16 AM
RECENT RESEARCH A recent study (August, 1996) exploring the effect of Hypericum perforatum on depression re vealed some fairly stunning results. The British Medical Jo u rn a l published the results of one major studies, which consisted of twenty - three randomized trials, including a total of 1757 outpatients with mainly mild or moderately seve re depressive disorders. Testing was conducted with single preparations and combinations of extracts of the plant, and with placebo and anther drug treatment. As just mentioned, the results were very promising. In all aspects of the study, Hypericum extracts were shown to be “significantly superior” to placebo and similarly effective as standard antidepressants. There were nearly twice the number, percentage-wise, of dropouts due to side effects from the standard drugs than those taking the Hypericum extracts. Side effects occurred in eighty-four patients using standard antidepressants, while only fifty patients taking the Hypericum extracts experienced side effects. And the scores on the Hamilton depression Scale, which measures severity of one’s depression, showed those taking Hypericum treatments scored slightly higher than those taking the standard antidepressant and significantly higher than those taking the placebo. 9 This study provides some firm ground for St. John’s wort to stand on in the treatment of depression, both in sheer numbers and its quality of treatment. Another contemporary study, carried out in 1995 by Witte, et. al, showed the Linde study to be accurate in its findings. This particular study, carried out as a multicenter, placebo-controlled double-blind trial, used a highly concentrated Hypericum preparation to treat ninety-seven outpatients. The course of the illness was assessed with the Hamilton Depression Scale, the von Zerssen Depressivity Scale and the Clinical Global Impression Scale. The authors of the study noted this in their abstract: Treatment resulted in an appreciable improvement in the symptoms of depression, and the seventy percent response rate (n=43) corresponded to that of chemical antidepressants. The preparation also showed an anxiolytic effect. The substance [hypericum] was extremely well tolerated, and no side effects were reported by any of the patients.10 Again, this study’s findings correlate that of the Linde and other studies in that treatment with Hypericum is at least as effective as standard synthetic antidepressants without producing near the number of side effects. The Nursing Times also reported on recent findings dealing with Hypericum’s effect on depression. Stating that psychiatric medications are notorious for their undesirable side effects, and that the need for safer antidepressants is widely acknowledged, the blurb refers to a double-blind study, done by G. Harrer and H. Sommer (published in Phytomedicine, 1994 (1): 3-8), using St. John’s wort on 105 patients experiencing mild to moderate depression. They were aged twenty to sixty-four and had diagnoses of “neurotic depression or temporary depressive mood.” Patients were divided into two groups and monitored over four weeks, with one group receiving 300 mg of Hypericum extract three times daily and the other group receiving a placebo. All patients received psychiatric evaluations before the start of the study and after two and four weeks of treatment.11 The results of the study support the findings of other recent studies dealing with Hypericum and depression: 67 percent of the Hypericum group had responded positively to the treatment without any adverse side effects, whereas only 28 percent of the placebo group displayed any improvement. Harrer and Sommer state that the patients treated were experiencing strictly mild forms of depression; combining this with the study’s results and the results of other studies suggest that Hypericum treatment can be a very effective treatment for mild to moderate depression without severe side effects. The authors themselves even recommended that Hypericum should be considered as a remedy of choice. 12 These and other studies point to the strong possibility of using St. John’s wort, and specifically hypericin, on a wide Scale to treat various forms of depression. Linde’s study suggests that St. John’s wort may have its most valuable asset in that of few or no side effects, something many sufferers of depression are very concerned about. The authors do note, however, that more research is necessary, especially in determining the severity and nature of depression, length of treatment, treatment dosage, preparation of Hypericum extracts, and occurrence of long-term side effects. Nevertheless, the results of this study and others are extremely promising for the millions of those who suffer from depression.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=627) WHAT IS A FREE RADICAL?
Date:
July 13, 2005 09:57 AM
WHAT IS A FREE RADICAL?Free radicals are unstable, unpredictable structures that pose a potential threat to healthy molecules on a cellular level. In their atte mpt to become stable, they assault and randomly impact healthy molecules, altering their functions in the process. TO COMPLETLEY ELIMINATE FREE RADICALS, YOU MUST STOP BREATHING The very act of breathing oxygen activates these reactive chemical structures. To make matte rs wo rse, because our generation, more than any other, is exposed to a number of potentially harmful environmental substances, free radical formation can reach epidemic proportions. Some of the more dangerous of these include:
EVEN EXERCISE HAS ITS PERILS Exercising, as beneficial as it is, can initiate the release of free radicals within our cellular systems. Aerobic exercising produces oxidation products. Many of these compounds are not neutralized by our internal safety mechanisms and an overload can occur. Supplementing the diet with efficient antioxidants is highly recommended for eve ryone, but especially for those who exercise on a regular basis. WHY ARE FREE RADICALS SO DANGEROUS A free radical can destroy a protein, an enzyme or even a complete cell. To make matte rs wo rse, free radicals can multiply through a chain reaction mechanism resulting in the release of thousands of cellular oxidants. When this happens, cells can become so badly damaged that DNA codes can be altered and immunity can be compromised. Contact with a free radical or oxidant on this Scale can create cellular deterioration, resulting in cancer and heart disease. Tissue breakdown from this oxidative stress can also occur which can contribute to aging, arthritis and whole host of other degenerative conditions. “Through free radical reactions in our body, it’s as though we’re being irradiated at low levels all the time. They grind us down.”3 PREMATURE AGING AND FREE RADICALS: Frequently, the oxidative stress caused by free radicals results in what we refer to as the aging process. While aging is inevitable, many of us hasten its outcome by not protecting ourselves, hence, we age prematurely. The early onset of wrinkling, arthritis, circulatory disorders, diabetes, heart disease and hardening of the arteries can result from free radical damage that could have been minimized by consistently taking strong antioxidants like Pycnogenol. More and more research suggests that it is a lack of certain protective nutrients, like the bioflavonoid compounds contained in Pycnogenol, which increases our risk of cancer and other degenerative diseases.4 WHY A NUTRITIOUS DIET DOES NOT AFFORD US ENOUGH PROTECTION “They (antioxidants) may be much more important that doctors thought in warding off cancer, heart disease and the ravages of aging—and, no, you may not be getting enough of these nutrients in your diet.”5 Clearly, while diet modifications are invaluable, diet alone cannot provide the kind of physiological defense the body requires to inhibit free radicals before they cause biological harm. While there is no way to escape our exposure to free radicals, we can minimize potential cellular destruction by reducing their numbers.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=605) History
Date:
June 24, 2005 01:13 PM
HISTORY Because 20th century medical practices have routinely over - prescribed antibiotics, the notion of a natural antibiotic with virtually no side-effects is intriguing to say the least. Echinacea is one of several herbs which possesses antibacterial, antiviral and antifungal properties. In a time when new life-threatening microbes are evolving and pose the threat of modern-day plagues, herbs such as echinacea are particularly valuable. More and more health practitioners are focusing on fortifying the immune system to fight off potential infections rather than just treating infection after it has developed. Echinacea is enjoying a renaissance today. During the late 1980’s, echinacea re-emerged as a remarkable medicinal plant. In addition to its infection fighting properties, echinacea is known for its healing properties as well. As was the case with so many herbs, echinacea lost its prestige as a medicinal treatment with the advent of antibiotics. It has experienced a resurgence over the last two decades. Echinacea has several other much more romantic names including Purple Coneflower, Black Sampson and Red Sunflower. It has also become the common name for a number of echinacea species like E. angustifolia, E. purpurea, and E. pallida. The genus derives its name from the Greek word echinos which refers to sea urchin. This particular association evolved from the prickly spiny Scales of the seed head section of the flower. Historically, echinacea has sometimes become confused with Parthenium integrifolium. The word echinacea is actually apart of the scientific latin term, echinacea angustifolia, which literally translated means a narrow - leafed sucker. The plant grows wild as a perennial exclusively in the midwestern plains states, but can be cultivated almost anywhere . Echinacea leaves are pale to dark green, coarse and pointy. Its florets are purple and its roots, black and long. Echinacea has a strong Native American link in the Central Plains. Native Americans are credited with discovering the usefulness of this botanical without knowing its specific chemical properties. It was routinely used by Na t i ve Americans to treat toothaches, snakebite, fevers and old stubborn wounds. Native Americans thought of echinacea as a versatile herb that not only helped to fight infection, but increased the appetite and s t rengthened the sexual organs as well. The juice of the plant was used to bathe burns and was sprinkled on hot coals during traditional “sweats” used for purification purposes. It is also believed that some Native Americans used echinacea juice to protect their hands, feet and mouths from the heat of hot coals and ceremonial fires.1 According to Melvin Gilmore, An American anthropologist who studied Native American medicine in the early part of this century, Echinacea was used as a remedy by Native Americans more than any other plant in the central plains area. In time, early white settlers learned of its healing powers and used the plant as a home remedy for colds, influenza, tumors, syphillis, hemorrhoids and wounds. Dr. John King, in his medical journal of 1887 mentioned that echinacea had value as a blood purifier and alterative. It was used in various blood tonics and gained the reputation of being good for almost every conceivable malady. It has been called the king of blood purifiers due to its ability to improve lymphatic filtration and drainage. In time, echinacea became popular with 19th century Eclectics, who were followers of a botanic system founded by Dr. Wooster Beech in the 1830’s. They used it as an anesthetic, deodorant, and stimulant. By 1898, echinacea had become one of the top natural treatments in America. During these years, echinacea was used to treat fevers, malignant carbuncles, ulcerations, pyorrhea, snake bites and dermatitis. In the early twentieth century, echinacea had gained a formidable reputation for treating a long list of infectious disease ranging from the commonplace to the exotic. The Lloyd Brothers Pharmaceutical House developed more sophisticated versions of the herb in order to meet escalating demands for echinacea. Ironically, it was medical doctors who considered echinacea more valuable than eclectic practitioners. Several articles on echinacea appeared from time to time in various publications. Its attributes we re re v i ewed and, at times, its curative abilities ranged from the sublime to the ridiculous. In 1909, the Council on Pharmacy and Chemistry of the American Medical Association decided against recognizing echinacea as an official drug, claiming that it lacked scientific credibility. It was added to the National Formulary of the United States despite this type of negative reaction and remained on this list until 1950. Over the past 50 years, echinacea has earned a formidable reputation achieving worldwide fame for its antiviral, antifungal and antibacterial actions. Consumer interest in echinacea has greatly increased, particularly in relation to its role in treating candida, chronic fatigue syndrome, AIDS and malignancies. Practitioners of natural medicine in Eu rope and America have long valued its attributes. In recent, years, German research has confirmed its ability to augment the human immune system. Extensive research on echinacea has occurred over the last twenty years. Test results have s h own that the herb has an antibiotic, cortisone-like activity. Echinacea has the ability to boost cell membrane healing, protect collagen, and suppress tumor growth. Because of its immuno-enhancing activity, it has recently been used in AIDS therapy. Research has proven that echinacea may have p rofound value in stimulating immune function and may be particularly beneficial for colds and sore throats.3
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=412) CLINICAL APPLICATIONS OF CAPSICUM
Date:
June 23, 2005 11:20 AM
CLINICAL APPLICATIONS OF CAPSICUM Capsicum is a remarkable whole body stimulant that can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain and fight off infection. One very authoritative work on African plants suggests that Capsicum’s “regular ingestion is highly beneficial in hemorrhoids, varicose veins, anorexia, liver congestion and vascular conditions . . .the indigenous inhabitants of Africa and of the Antilles are remarkably free form all of these conditions as they use Capsicum fruit in their diet.”10 Most of the therapeutic actions of Capsicum are attributed to the alkaloid or glucoside content of the herb.11 The latest scientific studies conducted with Capsicum will be discussed in subsequent sections. Herbal Catalyst Because Capsicum boosts peripheral circulation and stimulates organ secretion, it expedites the therapeutic delivery and action of other herbs. In other words, the medicinal benefits of these herbs reach infected or inflamed tissue more rapidly due to enhanced blood flow.12 Consider the following statement: “Cayenne will insure the rapid and even distribution of the active principles of the rest of the herbs to critical function - al centers of the body, including those involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation. Cayenne is included in several other blends for this reason. In extremely small quantities it can dramatically increase the efficiency of most other herbs.”13 Many health practitioners believe that the key to healing is CAPSICUM stimulation. Capsicum stimulates eve rything from blood flow to peristaltic action in the stomach, to intestinal transit time. The re m a rkable ability of Capsicum to stimulate organ secretion and even heart action makes it one of the strongest natural stimulants known. Se veral different kinds of herbal blends targeting various body systems will utilize Capsicum to boost the formula’s efficacy. Cardiovascular Tonic Capsicum is said to be unequaled for its ability to boost circulation and increase heart action. Interestingly, cultures who consume significant amounts of cayenne pepper in their diet have much lower rates of cardiovascular disease.14 Capsicum exerts a variety of desirable actions on the entire card i ovascular system. It has the extraordinary ability to enhance cardiovascular performance while actually lowering blood pressure.15 A quote taken from a card i ovascular publication re a d s , “Capsaicin has also been shown to prolong cardiac action potential in atrial muscle . . .”16 Michael T. Murray, N.D., has stated, “ Cayenne pepper [Capsicum] should be recommended as a food for its beneficial antioxidant and cardiovascular effects.”17 Herbalists have considered Capsicum as a superior “f o o d” for the heart. In fact, in cases where a heart attack is suspected administering capsicum in hot water has been thought to help lessen the severity of the attack. Capsicum can also be placed on or under the tongue in emergencies involving heart attack, stroke or hemorrhaging. 18 Note: Using Capsicum for any heart-related problem, especially a suspected heart attack should never take the place of medical attention or a physician’s care. CAPSICUM Blood Cholesterol Reducer Various studies have conclusively demonstrated that Capsicum reduces the risk of developing atherosclerosis (hardening of the a rteries) by reducing blood cholesterol and triglyceride levels .19 Additional clinical studies conducted in India found that when cayenne was ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels was significantly inhibited. In addition, bile acids and free cholesterol were subsequently eliminated from the body through the stool.20 Interestingly, these tests revealed that using Capsicum was actually more effective in reducing cholesterol that capsaicin alone.2 1 Daniel Mowrey, Ph.D., emphatically points out that this is just one of many examples of the superiority of whole botanicals as opposed to their isolated components.22 Note: Using Capsicum in combination with Hawthorn is a particularly good cardiovascular tonic. Blood Pressure Equalizer While an added bonus of Capsicum’s capability to lower blood serum cholesterol is a decrease in blood pressure, additional evidence strongly suggests that the herb initiates other mechanisms that fight hypertension .23 “Cayenne, according to another study, also reduces the blood pressure in an even more direct manner: a number of years ago, a team of researchers discove red that capsaicin acts in a reflexive manner to reduce systemic blood pressure, a kind of coronary chemoreflex.”24 Adding Garlic to Capsicum creates an even better therapeutic blend for treating hypertension. Blood Detoxification CAPSICUM “Cayenne is a kind of catalyst in the blood purification process . . . it acts as a diaphoretic, stimulating the excretion of wastes in the swe a t . ”25 Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it would only stand to reason that it would also facilitate the faster removal of toxins from the bloodstream and lymphatic system. You may have already noticed that Capsicum is frequently added to blood-purifying herbal combinations. Circulatory Booster Researchers have found that the simulating action of Capsicum on surface capillaries can help to pre vent cold hands and feet.2 6 For this reason, it may be helpful for Reynaud’s Syndrome. Old remedies using Capsicum have even recommended placing it in socks to warm the feet and to help prevent frostbite. An old folk cure for a chilled body was a steaming hot cup of Capsicum tea. Free Radical Scavenger The rich flavonoid content of Capsicum gives it significant antioxidant capabilities. A recent study conducted in 1995 showed that Capsicum has a higher ascorbic acid content than chiles from the jalapeno or serrano varieties .27 Vitamin C and bioflavonoids can scavenge for dangerous free radicals which cause tissue damage and can predispose organs to degenerative diseases. Free radicals are found everywhere and are created as by-products of metabolic p rocesses including the act of breathing itself. Pollutants can expose the body to free radicals. An interesting study done in Mexico City and published in 1993 found that Capsicum extract was able to modulate the mutagenic activity of urban air samples.28 In other words, these potentially dangerous nitro - a romatic compounds found in polluted air were kept from mutating by red chile extract.29 Chemical breakdowns of Capsicum have also found that CAPSICUM the pepper is high in Provitamin A, which significantly contributes to its healing ability and immune fortification.30 Anti-Carcinogenic Compound Anti-cancer research recently tested Capsicum on laboratory rats and found that it does indeed demonstrate anti-cancer properties by inhibiting certain enzymes which can initiate the mutation of cells.31 What this implies is that taking Capsicum can afford the body some protection against the cellular mutation which occurs in malignant growths. Capsicum actually inhibited the formation of dangerous metabolites under laboratory conditions where they should have normally been activa t e d .3 2 This study implies that Capsicum may have many more sophisticated bio-chemical actions than previously thought. An Impressive Pain Killer Capsaicin has recently emerged as a remarkably effective pain reliever and has become the subject of recent clinical research . Applying capsaicin in cream or ointment form to painful joints, scar tissue or other painful conditions involving peripheral nerves confuses pain transmitters. In other worlds, capsaicin temporarily disrupts sensory nerve cell biochemistry there by impeding the relay of pain sensations from the skin surface. It does this by inhibiting a neurotransmitter called substance P. This specific compound is thought to be the main mediator of pain impulses from peripheral nerve endings.33 Substance P has also demonstrated its ability to inhibit inflammatory pain generated in arthritic joints in much the same way.34 Today, several over-the-counter topical preparations utilize capsaicin for the pain of arthritic joints. The ability of Capsicum to control severe and unresponsive pain is significant, to say the least. Modern clinical utilization of topical capsaicin may offer signifi-cant relief for a number of painful conditions including: diabetic neuropathy, cluster headaches, post-amputation pain, post-mastectomy pain, shingles and painful scar tissue.35 POST-SURGICAL PAIN In the early spring of 1996, prime time national news show s reported that scientists had found that individuals who had suffered from chronic pain in post-surgical scars (heart bypass, arterial grafts, etc.) were successfully treated with topical preparations containing capsaicin. While this may have been news to many of us, clinical studies had been already published for several years that capsaicin held profound value for various kinds of pain which did not respond to established medical treatments. Typically surgical scars and regions around them can produce persistent pain or can be very sensitive to the touch even when completely healed. This type of pain phenomenon seems to respond well to capsaicin ointments and creams. POST-MASTECTOMY PAIN When capsaicin preparations were applied following mastectomy or breast reconstruction, pain was significantly relieved. Se veral double blind studies found that using capsaicin creams four times daily for 4 to 6 weeks resulted in much less frequent occurrence of sharp, jabbing pain.3 6 All thirteen patients studied had a 50 percent or greater improve m e n t .3 7 Various unpleasant sensations other than pain also improved with topical applications of capsaicin creams.38 MOUTH SORES FROM RADIATION OR CHEMOTHERAPY A fascinating study conducted at the Yale Pain Management Center discove red that capsaicin could ve ry significantly lessen pain caused by mouth sores which frequently develop after chemotherapy or radiation.39 Apparently delivering the capsaicin in the form of soft candy (taffy) enabled the substance to be retained in the mouth long enough to desensitize the nerve endings causing the pain. Each one of the eleven case studies re p o rted that their pain had decreased and in two patients, it stopped entirely.40 DIABETIC NEUROPATHY Diabetic neuropathy is a painful nerve condition which can develop in cases of prolonged diabetes. Several double-blind studies have supported the considerable value of capsaicin creams for relieving the pain associated with this disorder.41 The results of a controlled study using Capsicum for seve re cases of diabetic neuropathy which did not respond to conventional therapy were published in 1992. A cream containing Capsicum was applied to painful areas four time a day and pain was carefully e valuated for 8 weeks at two-week intervals. The results we re impressive, to say the least. In the 22 patients who used the Capsicum the following results we re re c o rded: “Capsaicin tre a tment was more beneficial than vehicle treatment in the overall clinical improvement of pain status, as measured by physician’s global evaluation and by a categorical pain severity Scale . . . In a follow-up study, approximately 50 percent of the subjects reported improved pain control or were cured . . .”42 No t e : While there was a burning sensation when the Capsicum c ream was first applied, some subjects found that its magnitude and duration lessened with continued application.43 SHINGLES The FDA has approved capsaicin-based ointments for the treatment of pain that results from diseases like shingles. Again, numerous studies have documented the value of capsaicin for decreasing the miserable nerve-related pain associated with shingles. The general consensus derived from these tests were that approximately 50 p e rcent of people suffering from shingles responded well to capsaicin creams, some even after 10 to 12 months.44 Note: If blisters accompany a shingles outbreak, it is better to wait until they have healed before using any capsaicin-based ointments or creams. RELIEF FOR BURNING FEET Frequently an uncomfortable “burning” sensation in the feet will occur in many people, particularly in diabetics. As ironic as it may seem, using capsaicin creams may actually alleviate this burning. “In various studies, diabetics who treated their burning feet with capsaicin got greater improvement and we re able to walk more easily than those not using the cream.”45 In addition, using topical applications of capsaicin as opposed to strong, oral drugs is much more preferable. ARTHRITIS PAIN Clinical tests have confirmed that topical capsaicin ointments substantially alleviate the miserable pain that characterizes osteoand rheumatoid arthritis.46 These studies revealed that using 0.075 capsaicin cream reduced tenderness and pain.47 Dr. Michael T. Murray writes: “ . . . seventy patients with osteoarthritis and thirty - one with rheumatoid arthritis received capsaicin or placebo for 4 weeks. The patients were instructed to apply 0.025 percent capsaicin cream or its placebo to painful knees four times daily. Significantly more relief of pain was reported by the capsaicin-treated patients than by the placebo patients throughout the study . . .”48 Anyone suffering from osteo or rheumatoid arthritis should evaluate the effectiveness of capsaicin ointments for joint pain. Ester Lipstein-Kresch, M.D., has studied the effectiveness of capsaicin creams for arthritis and has stated: “You need to apply it three or four times a day on the affected area for at least two weeks before you’ll see any improvement. An initial burning sensation at the site is not unusual for the first few days, but this goes away with continued application.”49 Note: Capsaicin is also useful for tennis elbow due to its ability to block the transmission of pain. MIGRAINE HEADACHES (CLUSTER TYPE) Topical applications of capsaicin ointments intranasally may also help to relieve the pain of a specific kind of migraine headache called cluster headaches. Cluster headaches are characterized by s e ve re pain which typically radiates around one eye. The term “cluster” refers to the fact that these headaches tend to occur in clusters of one to three per day and can recur at intervals. Headache pain and severity we re reducing in groups using intranasal capsaicin.5 0 This type of capsaicin treatment should be done under a physician’s care. There is some speculation that capsaicin may be more effective in pre venting migraines before they develop into a full blown attack.51
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=405) Vision Quest - help fight eye problems.
Date:
June 18, 2005 08:34 AM
Vision Quest by Phyllis D. Light, RH Energy Times, February 11, 2004 Since your eyes are in constant use every day, exposed to the damaging energy of sunlight and pollutants that waft through the air, these delicate orbs are often in danger of wearing out. To keep this vital part of your anatomy functioning as you age, you have to feed and care for your eyes properly. Otherwise, you are in real danger of losing your vision and independence. Your vision may be in danger. Experts estimate that 8 million Americans over the age of 55 are at serious risk of blindness linked to a condition called age-related macular degeneration (AMD). AMD can wipe out your central vision and is the primary cause of blindness in Western society. While AMD causes no pain, it blurs the sharp, central vision necessary for driving, reading and other activities where you need to see either up close or straight ahead. During AMD, the macula, the part of the eye that allows you to pick out fine detail, is destroyed. The macula sits at the center of your retina, the nerve center at the back of your eye that senses light and sends optic signals to the brain. Age is not the only risk factor for AMD. Scientists have isolated a genetic defect that can lead to some forms of macular degeneration (Nature Genetics 2001; 27:89-93). Smoking and excessive exposure to sunlight are other hazards best avoided if you want to save your sight. In many cases, AMD progresses so slowly that victims of this condition don't even notice that their vision is deteriorating until much of it is irrevocably gone. Dry and Wet AMD Wet AMD occurs when blood vessels in back of the retina start to overgrow and leak blood. As this occurs, blood and other fluids push on the macula and quickly damage its sensitive nerve endings. When wet AMD occurs, you lose your central vision rapidly. If straight lines appear wavy to you, you may be suffering from wet AMD. If you notice this or other unusual vision changes, contact an eye care specialist as soon as possible. You need what is called a comprehensive dilated eye exam that can uncover signs of AMD. Dry AMD strikes the eye when light-sensitive cells in the macula slowly deteriorate, gradually blurring central vision in the affected eye. As dry AMD progresses, a blurry spot in the center of your vision may appear. Eventually, as more of the macula becomes dysfunctional, the central vision in the eye can gradually disappear. The most common sign of dry AMD is slightly blurry vision. This can make it hard to recognize faces and also make it harder to read without very bright light. Dry AMD generally attacks both eyes, but vision can be lost in one eye while the other eye stays normal. In the early stages of dry AMD, drusen, yellow deposits that gather under the retina, may form. Dry AMD progresses in three stages:
Vitamins and Minerals for AMD Fortunately, scientists have found ways to combat AMD: An analysis of a study called the national Age-Related Eye Disease Study (AREDS) shows that more than 300,000 Americans could avoid losing their sight to AMD if they took daily supplements of antioxidant nutrients and zinc. This conclusion, reached by scientists at Johns Hopkins' Wilmer Eye Institute, is based on research involving more than 4,500 adults suffering various stages of AMD. The study demonstrated that people who already had some AMD could lower their risk of the more advanced form of this condition by 25% when they took vitamin C, natural vitamin E and beta carotene along with zinc. Those suffering from advanced AMD lowered their chances of losing vision by about 19%. (Supplements did not affect the risk of cataracts or the chances of some vision loss for people in the early stages of AMD.) " Without treatment to reduce their risk, we estimate that 1.3 million adults would develop the advanced stage of AMD," says Neil M. Bressler, MD, professor of ophthalmology at Johns Hopkins and author of the current study, published in Archives of Ophthalmology (11/03). According to Dr. Bressler and the other researchers, people who now have intermediate AMD (some vision loss) in one eye have about a 1 in 16 chance of having their vision deteriorate until they have advanced AMD. They also calculate that about 1 in 4 of those with intermediate AMD in both eyes and 43% of those with advanced AMD in one eye will develop advanced AMD in five years without treatment. In their view, older people at risk of AMD blindness should take daily supplements of 500 milligrams of vitamin C, 400 milligrams of natural vitamin E, 15 milligrams of beta carotene, 80 milligrams of zinc as zinc oxide and 2 milligrams of copper as cupric oxide. Evidence also exists that a diet which is high in fat can cause AMD to progress to an advanced stage. The exceptions: The healthy fats found in fish and nuts (Archives of Ophthalmology 2003; 121:1728-37). Lutein Protection Oddly enough, some of the same pigments that color vegetables and other foods also color your eyes. And scientists believe that those pigments, which are classified as carotenoids, help protect the eyes by helping them fight off the negative effects of caustic molecules called free radicals. Free radicals are formed when the energy from sunlight strikes the eyes and disrupts the composition of natural chemicals found there. When scientists compared healthy eyes with eyes suffering from AMD, they found that AMD eyes contained lower levels of lutein and zeaxanthin, carotenoid pigments contained in egg yolk, spinach, broccoli and other dark green vegetables (Ophthalmology 2003; 109:1780). Furthermore, they found that levels of these chemicals generally decline as you grow older. " This research is a major step toward large-Scale clinical studies to prove the extent to which lutein and zeaxanthin protect against age-related macular degeneration," says Paul S. Bernstein, MD, PhD, at the University of Utah School of Medicine at Salt Lake. "We know that these carotenoids are specifically concentrated in the macula of the human eye." Dr. Bernstein adds that, as you age, taking supplements containing lutein and other antioxidants may lower your AMD risk. In his investigation, people with AMD who did not take lutein had one-third less lutein in their eyes than older people whose vision was normal. Avoiding Cataracts Another eyesight hazard is cataracts, in which the eye's lens-the part that focuses incoming light onto the retina-becomes cloudy. Cataracts form when the proteins found in the normally clear lens become damaged; signs include progressively blurred vision (especially outdoors), focusing problems, seeing streaks of light from headlights and stoplights, and colors that look faded. Cataract is the leading cause of blindness worldwide, according to the World Health Organization. One of every six Americans 40 and older suffers from some degree of cataract; it affects half of all Americans who reach age 80. Nuclear cataracts, the most common form of this disorder, develop in the center of the lens and tend to grow slowly. Cataracts may also develop at the back of the lens; this form is linked to eye trauma and long-term use of certain medications, including steroids. Like AMD, cataracts become more common as people age. Up to 40% of individuals between the ages of 75 and 85 have them, compared with only 5% to 10% of those folks under the age of 65. And like AMD, sunlight exposure and smoking increase the risk of developing cataracts, as does the presence of diabetes. Lutein and zeaxanthin, the carotenoids that are so plentiful in the macula, are also found in the lens (although in lower concentrations), leading many researchers to believe that these nutrients may help drop your risk of cataract development. Early studies indicate that an increased intake of lutein and zeaxanthin reduces one's chances of needing cataract surgery, the most common surgery in the United States (American Journal of Clinical Nutrition 1999; 70(4):509-16; 517-24). Antioxidants and the Lens Scientists believe that free-radical damage is a leading cause of cataracts, and so it isn't surprising that antioxidants have proved useful in preventing this problem. Almost 500 women filled out diet questionnaires as part of a very large research effort called the Nurses' Health Study; those who had taken vitamin C supplements for 10 years or longer enjoyed the lowest rates of nuclear cataracts (Archives of Ophthalmology 2001; 119:1009-19). So the answer to lowering your risk of eye problems is clear, whether you are already in your mature years or plan to be someday: Lead a healthy, eye-friendly lifestyle, eating a diet filled with colorful fruits and vegetables. Take frequent walks and jogs around the block. And yes, when you kick back and take your just-as-frequent doses of antioxidant supplements, you're allowed to take your sunglasses off and see the world clearly.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=374) Catch Your Breath
Date:
June 14, 2005 05:56 PM
Catch Your Breath by Carl Lowe Energy Times, October 10, 2004 Asthma is on the rise. This serious breathing problem already afflicts 300 million people around the world and is expected to hinder the lung function of 400 million people in 20 years (Annual World Asthma Meeting, 2/17/04). In the US, asthma continues to strike our kids. According to the US Environmental Protection Agency (2/24/03), the rate at which kids developed asthma doubled between 1980 and 1995. By 2001, 6.3 million American kids had asthma. The cost of treating all these kids: more than $3 billion a year. Few researchers are prepared to state definitively why asthma rates have continued to climb during the past two decades. However, many investigators point to factors that seem inextricably linked to this disorder, which is marked by wheezing, shortness of breath and coughing spells. CO2 Buildup A report from the American Public Health Association and researchers at Harvard puts a lot of the blame for the high rate of asthma on global warming, smog and the atmosphere's growing burden of carbon dioxide. These are linked to industries and car exhaust that release pollution. In this increasing burden of toxins released into the atmosphere, the rate of asthma among toddlers has grown to be particularly worrisome. Their rate of asthma has climbed more than twice the national average: by 160% between 1980 and 1994. According to these researchers (Inside the Greenhouse: The Impacts of CO2 (Carbon Dioxide) and Climate Change on Public Health in the Inner City), global warming-which involves large increases in atmospheric carbon dioxide released by internal combustion engines and and industrial processes-has fomented the asthma epidemic in several ways: • Extra heat in the atmosphere has stimulated rapid plant growth that results in more fungus, pollen and spores; this causes allergies that often lead to asthma. Weeds like ragweed, which release allergenic particles, have greatly increased during the past few years. • Extreme weather has caused more floods and damp houses, leading to more indoor air pollution from molds. • Diesel pollutants are now combining with pollen and mold to irritate lungs, causing troublesome allergic reactions. Bus Fume Hazards The report notes that in neighborhoods like Harlem, in New York City, 25% of all children suffer asthma. Rates are particularly high in children who live in apartments that are located along bus routes. A finding that surprised the scientists is the fact that carbon dioxide released by city traffic and the burning of coal and natural gas persists over urban areas, causing a dome of CO2 pollution. Research on air quality in New York City, Phoenix and Baltimore shows that these lingering CO2 domes contain from 400 parts per million (ppm) of carbon dioxide to 600 ppm. Those levels are significantly above the global average of 379 ppm. Over the course of the earth's history, going back more than 400,000 years before the Industrial Age, research shows the atmosphere has averaged only 180 to 280 ppm. Nighttime Distress Breathing difficulties that increase at night can point to asthma, according to Robert Fink, MD: "Asthma can be a nocturnal disease, at its worst between 10 pm and 4 am, when cortisol [a hormone that regulates many bodily functions] levels are lowest" (Pediatric Asthma: Diagnosis and Treatment Goals, Medscape). Dr. Fink says that if problems with breathing are bad enough to interfere with sleep, a health practitioner should be consulted to analyze the difficulty. Diet and Asthma Although nobody can guarantee protection against asthma, research suggests that eating plenty of fruits and vegetables can significantly reduce your risk. For instance, a study in Australia found that people who ate the most apples and pears reduced their chances of suffering from this breath-robbing disorder. In research involving about 1,600 people, aged 20 to 44, they found that those who consumed the largest quantity of these fruits enjoyed the lowest rate of asthma (AJCN 2003; 78:414). This is the latest study to confirm the fact that apples and other fruits help to keep lungs healthy. " There is extensive evidence from studies over the last 10 to 15 years that a diet rich in fruits and vegetables is beneficial to lung health," observes Carol Trenga, PhD, a research scientist at the University of Washington in Seattle. "The most compelling evidence is linked to fruits high in vitamin C, which are associated with improved lung function in the general population of adults and children." Produce for Smokers Quitting smoking represents one of the best ways to reduce lung disease. But even if you smoke, research on smokers has found that those who ate a moderate amount of fruits and vegetables have fewer lung problems (American Thoracic Society 97th International Conference 5/2001). And you don't have to change your diet very much to make a difference: In that research, merely eating one and half pieces of fruit a day or eating about a tablespoon of vegetables daily significantly dropped smokers' chances of serious lung disease. Fruits and Veggies to the Rescue In a study at the University of Nottingham, United Kingdom, scientists looking at the diets of more than 2,500 people found that eating five or more apples or three tomatoes a week increased lung function. Eating apples and tomatoes also reduced the risk of wheezing. " The likelihood is that any effect is due to the concerted action of all the nutrients in apples and tomatoes, especially the antioxidants that are particularly rich in the peel of apples and contribute to the coloring of tomatoes," says researcher Sarah Lewis, PhD. " Antioxidants may work by protecting the airways against the insult of tobacco smoke and other atmospheric pollutants," she adds. Dr. Trenga recommends that everyone eat at least five servings of fruits and vegetables a day. She also notes, "[I]t is reasonable to suggest modest supplementation with for example, vitamin C (250-500 mg twice/day) and vitamin E (up to 400 IU per day), in at-risk populations as a complementary therapy after considering the specific needs of the individual...These levels are very safe and have other health benefits (such as vitamin E and heart disease) in addition to potentially improving lung health." Herbal Relief Since asthma is linked to allergies, herbs that help to quell respiratory allergies can possibly lower your risk of asthma. A blend of standardized herbal extracts that contains Phyllanthus emblica (Indian gooseberry or amla), Terminalia chebula (Harda or Haritaki), Terminalia bellerica (bedda nut tree), Albizia lebbeck (Indian walnut), Zingiber officinale (ginger root), Piper longum (Indian long pepper), and Piper nigrum (black pepper) has been found to improve breathing and reduce the effect of allergies (FASEB J 2004; Vol II:A912, Abs. 600.8). Other studies have shown that these herbs can relieve nasal congestion, ease sneezing and clear bothersome mucus (J Am Coll Nutr 22(5): Abs 46, 2003). Antibiotic Avoidance Avoiding antibiotics may also lower the risk of asthma. " Over the past four decades there has been an explosive increase in allergy and asthma in westernized countries, says Mairi Noverr, PhD, a researcher who has looked at the lin between antibiotic use with asthma and allergies. " We propose that the link between antibiotic use and dysregulated pulmonary immunity is through antibiotic-induced long term alterations in the bacterial and fungal GI microflora." In other words, Dr. Noverr's research shows that beneficial bacteria in people's intestines, which take part in strengthening immunity and regulating the immune response to pollen, may have been harmed by the overprescription of antibiotics by physicians. Dr. Noverr and his fellow researchers gave lab animals antibiotics before exposing them to candida albicans (a yeast infection). They then exposed the animals to mold spores. The result: a greater sensitivity to inhaling the spores and breathing problems similar to what people experience during hay fever season (104th General Meeting American Society of Microbiology). " The studies presented here are the first direct demonstration that antibiotic therapy can promote the development of an allergic airway response," says Dr. Noverr. On a global Scale, the outlook for asthma is worrisome. As other countries continue their industrial growth, the burden on the earth's atmosphere will grow. Meanwhile, few serious measures are being taken to reduce global warming, and the national diet frequently neglects lung-friendly vegetables and fruits. But within that uncertain scenario, you can boost your chances of healthy lungs: Eat more apples. Stay away from smoky buses. Hope for clear skies.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=355) Power Meals - Shakes, smoothies and bars help make getting good nutrition easy.
Date:
June 14, 2005 08:28 AM
Power Meals by Phyllis D. Light, RH Energy Times, March 12, 2004 Choices, choices, choices: For convenience, nutrition and either low-calorie or low-carb dieting, you now have an enviable range of choices. Shakes, smoothies and bars help make getting good nutrition easy. Whatever your inclination, drinks and bars offer a shortcut to daily nutrition without cooking. And whether you use them as meal replacements, diet aids or healthy snacks, these power meals fill you up without filling you out. That's the main reason these items have grown in popularity in natural food stores among the nutritionally knowledgeable searching for healthier alternatives to fast food. No matter how hectic your day, you have no excuses anymore for missing your daily required antioxidants and minerals. Either select a bar suited to your taste, or put your blender or food processor to work in creating drinks that use fresh fruits and veggies, yogurt, low-fat milk or ice and protein powders for maximum nutritional output. Quality note: always be sure to use organic foods for the best nutritional content, flavor and taste. Powerful Nutrition Prepared protein shake mixes and bars are ideal for losing weight, expanding personal energy or building muscle. Protein mixes are available in an assortment of flavors that are generally high in amino acids (protein building blocks) and low in carbohydrates. Of course if you are on a low-carb diet, forsake putting fruits and vegetables in your shakes; these items are too high in carbohydrates. What's more, bars not only provide a wealth of different tastes, but different bars are also tailored to different needs-whether you're seeking to lose weight, gain muscle or replace a meal, there's a bar out there just for you. If you use power shakes as meal replacements and you are on a low-carbohydrate diet, make sure the drink supplies plenty of protein and few carbohydrates. If you use either shakes or bars to replace one or more meals during the day, take a fiber supplement in addition. Fiber, which contains no calories, helps speed food through your digestive tract and may lower your risk of heart disease and cancer (Lancet 5/2/03). And remember: powders and bars should also be low in sugars and saturated fats. The weight-loss benefit: If you drink high-protein shakes or eat bars that taste good and leave you feeling satisfied, you'll have a better chance of sticking to your diet long enough to lose a significant amount of weight. Drink to Lose Research into weight loss has established protein shakes and bars as reliable diet aids. A study of 100 dieters between the age of 35 and 65 found that people who drank a daily soy protein shake lost more than 14 pounds each in three months (Eur J Clin Nutr 2003; 57:514). And in a study reported in the Journal of American Dietetic Association (3/01), folks who had a protein shake in place of one daily meal lost almost twice as much weight over 12 weeks than those who ate their regular food with the same amount of calories. Drinking your breakfast in the form of a protein shake can both increase your metabolism and help curb your appetite for the rest of the day. Researchers at Harvard University found that metabolism rose faster after eating a high-protein breakfast and that blood-sugar levels stayed high for about six hours after the meal (AHA Annual Conference on Cardiovascular Disease Epidemiology and and Prevention, 3/6/03). In comparison, when a sugary breakfast is consumed, blood-sugar levels rise quickly but fall rapidly, causing fatigue, tiredness and sleepiness. Protein shakes are especially effective when you are on a weight-loss plateau, trying to lose those last few tenacious pounds. (But shakes, smoothies and bars should not be your only meals of the day. Eat at least one low-calorie meal daily to supply nutrients that may not be in your shakes or bars.) Smoothie Operator Made with fruits and vegetables, smoothies are a tasty way of getting extra amounts of nutrients and soluble fiber. Using low-fat milk, yogurt, buttermilk or kefir, plus ice, creates a tempting and wholesome blend that lights up the taste buds. Powdered mixes can be used for added protein. Fruits and vegetables in your smoothies not only fill you up on relatively few calories, but they boost your energy and supply plenty of bioflavonoids (healthy, natural chemicals from plants), antioxidants, vitamins and minerals. The fiber in smoothies can help reduce cholesterol, relieve constipation and aid in the prevention of high blood pressure. For reduced calories and added heart health benefits, low-fat or no-fat milk products can be used in place of cream or regular milk in most recipes. For the best taste sensation, combine sour and sweet fruits together. Adding raw fruits and vegetables to smoothies provides natural enzymes that help with digestion and act as catalysts in hundreds of chemical reactions throughout the body. (You can also take enzymes in supplemental form.) Enzymes are not present in cooked foods since the heat of cooking destroys them. Nutrition for Kids If you have trouble getting your children to eat their fruits and vegetables, try giving them smoothies. Children can't resist these naturally sweet and healthy creations. According to Sally Fallon, author of Nourishing Traditions (New Trends Publishing), smoothies should be "high in quality, contain healthy fats, be naturally sweet, and contain fresh seasonal fruits and vegetables." Fallon also believes children should consume what are called lacto-fermented foods, including yogurt and kefir, which are aged to contain the kinds of friendly bacteria that normally live within our digestive tracts. For kids, Fallon also encourages the use of cream or cultured milk to ensure adequate fat and calcium, so important for the development of growing bodies. Smoothies are an interactive drink as far as children are concerned, since they love to help blend them. For extra nutrition power, add nutritional yeast, nut butters or ground flaxseeds. These supply additional vitamins and minerals, along with healthy fats. You can also add silken tofu to bump up the protein content. If your child is lactose intolerant, try mixing smoothies with rice milk, soy milk or juice. Bars Designed With A Woman's Needs in Mind The modern woman is a multitasking wonder, constantly juggling work and home responsibilities. So it's no wonder that bars aimed at women are among the most popular bars there are. Many women, in eyeing the bathroom Scale, shortchange themselves of the nutrients they need. That's why a woman's bar needs to provide minerals like calcium, a bone-building necessity. Women also need to ensure that a bar contains enough of the B vitamins, particularly folate. This is especially true if a woman is pregnant, or wants to be: Folate is crucial in helping to prevent neural tube birth defects. Folate also teams up with two other B vitamins, B6 and B12, to control homocysteine. This protein metabolism byproduct, when present in excessive amounts, is associated with heart disease. Another popular ingredient in women's bars is soy, which has been duly recognized for its heart benefits. Studies also indicate that soy may help keep bones strong. (Not to mention the fact that the moisture soy holds helps make a bar's texture that much more appealing!) The Protein Game If you are unsure about how much protein you need each day, you are not alone. Are you getting too much, not enough, or just enough? Most people need between 45 and 60 grams of protein daily, and most protein shakes contain about 14 and 20 grams of protein per serving (check your labels). No matter what your nutritional needs are, you may find an answer in a smoothie, shake or bar. When it comes to power nutrition, tasting is believing!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=338) Best Bread ...
Date:
June 13, 2005 07:30 PM
Best Breads by Jane Lane Energy Times, December 9, 1999 Few of us can resist the seductions of freshly baked bread, warm and fragrant, poised on the edge of a steaming bowl of soup or painted with an aromatic swath of rosemary scented oil. Even those of us from the most culinary challenged households can recall the pleasures of the simple plump white dinner roll or flaky biscuit piled in a basket on the dinner table. Bread has blossomed from sideshow status beside the dinner plate to a full-Scale mealtime headliner, a scrumptious star enriched by nutritious grains, herbs, fruits and vegetables. Contemporary cooks build meals around crunchy cornbread or chewy focaccia, presenting soups or salads as satisfying counterpoints. Want to jump into the bread baking basket or hone your skills? Two top vegetarian chefs shared with Energy Times their passion for bread and their expertise in baking. See if you don't find that ardor contagious. Nancy Lazarus is a chef at the famed Moosewood Restaurant in Ithaca, New York, established in 1973 to serve up natural fare with a homecooked, vegetarian emphasis. The bill of fare changes daily at Moosewood, but there's one constant: a cup or bowl of soup, a salad and a thick slice of bread. Some loyal customers have ordered the daily special for 20 years. That's why bread occupies a cherished spot at Moosewood. Nancy Lazarus tells why and offers some of Moosewood's favorite bread recipes: "Cooking is like art; baking is like science; bread is like magic. No matter how much science you apply, you'll never have complete control: It'll do its own thing on some level, which is part of its charm, if you're charmed by that sort of thing. Breads come out differently depending on heat and humidity, the heat of the oven; yeast is a variable that can be slower or faster acting. "There are bread machines, of course, and they work. But they're not as satisfying as the real thing, the kneading, which can be almost therapeutic, and the control over the ingredients to your own specifications. "Bread is not that difficult. Know your own oven, to begin: Good insulation is important and how the heat travels around inside. Convection ovens are a wonderful thing. "There are difficult breads we recommend you buy at a good bakery: baguettes, Italian, French and Cuban that are crusty outside and soft inside. "But focaccia is easy. It's a yeasted bread that's better to make at home than buy because it's so fresh and you can control the toppings. It only requires one slow and one quick rising but you have to be there for a while. "Then there are quick breads that use baking soda or powder, like cornbread. If you want a good meal at home and can make only one thing, make a quick bread. They're satisfying and delicious warm from the oven; and the aroma of bread fills the house. A corn bread with tomato soup for supper is a nurturing meal good for vegans. "Popovers are fast and simple, a middle American 50s treat, but you do need a hot oven and 45 minutes. Also easy to make: sweet breads- carrot, banana, zucchini-and biscuits. "To reduce the fat in denser quickbreads and cakes, use applesauce. It gives body and moistness. "The number of wheat-sensitive people is rising dramatically. A theory I think makes sense is that in the last 30 years the varieties of wheat grown has been reduced to 1 or 2 that are more easily cultivated and harvested with the machinery available. People are overloaded with one type of wheat. "Gluten is the offending substance in wheat and some oats; try rice, tapioca and potato flours, which are denser and more fine and don't produce a good crust. Improve the crust by baking in a preheated cast iron skillet. "Also investigate chickpea flour. You don't make a loaf of bread with it- use it for flatbreads like papadam, which is in Indian cookbooks. And it's good for batter for vegetables. "Spelt is the closest to wheat flour in consistency but some people can be sensitive to it. "Visit a natural food store to check out the flours. The mills sometimes print handouts with recipes and a lot of those are real good, especially for what works with their flour. Or you may run into a baker who will whet your appetite with ideas and recipes. "Bread is the supreme comfort food. It can speak to us, and reassure us. The magic of bread and how it varies: There's something appealing in that. In today's world, food is predictable, and that's reassuring to some people. At Moosewood, things are always different, and that's good." Claire Criscuolo puts an intensely personal spin on the eclectically ethnic style of cooking at her esteemed vegetarian restaurant, Claire's Corner Copia. That 25-year-old institution in New Haven, Connecticut, reflects her zest for the freshest ingredients, robust flavors and inspired combinations. Claire, a teacher and advocate for healthful cuisine, pours her passion into her breadmaking as well: "Healthy bread is like anything else-it has healthy ingredients. We use the best organic unbleached flour and yeast, pure vanilla, whole eggs (not dried and powdered), whole milk and organic sour cream. You want to use good, fresh ingredients. It's the essence of healthy cooking. "I tell my staff, 'Don't use your soup pot as a garbage pail. Bread is the same. If the ingredients aren't at their freshest for serving, then they aren't right for other uses in the kitchen. "Our bread is very important at Claire's. We make a country white and a honey wheat in a pinwheel loaf-400 a day-and challah for the morning French toast with sauteed bananas or as buns for veggie burgers. "It's not practical to bake bread every day. We let our bread rise several times, punching it down again and again. For the home cook, it's time consuming. Even I'm happy to buy a good loaf of bread. "But anybody can bake bread. Combine flour, water and yeast and watch it grow! It's delights all your senses. And it a gratifies and satisfies. I was kneading it all by hand until we got up to 12 loaves a day. "I love a good oatmeal molasses bread; a whole wheat bread with walnuts, rosemary and finely chopped sweet onion sauteed in olive oil for a roasted vegetable sandwich; or an anadama bread with split pea soup. "Bread is part of a meal. It requires time and effort, but I can't think of many things worthwhile that don't."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=333) Don't Be Blue - Does winter got you singing the blues?
Date:
June 13, 2005 09:49 AM
Don't Be Blue by Phyllis D. Light, RH Energy Times, October 10, 2003 Have the gray skies of winter got you singing the blues? Do you feel tired, lost your creative spark, need extra sleep, can't get control of your appetite? If you nod in agreement to these queries, you may be one of the millions of people affected by SAD (seasonal affective disorder), also known as the "winter blues" or "cabin fever." Time to lighten up, throw off those lowdown winter blues and step up to more enjoyable feelings. Experts who study the winter blahs now acknowledge that you can blame much of winter's crankiness, moodiness and restlessness on short, cloudy days and a lack of sunlight. Low levels of sunlight trigger changes in hormones, increasing levels of melatonin (a hormone that normally helps you go to sleep) and decreasing serotonin (a hormone that improves mood). For many people, this hormonal tumult translates into a craving for sugary foods, a need for more sleep and a reduced sex drive. Although the exact cause of SAD is not known, researchers believe the pineal gland plays an important role in this disorder. This gland, located beneath the brain, makes melatonin in response to the amount of light that enters your eyes. Melatonin hormone is only produced in darkness. The darker your bedroom, the greater your melatonin production. Conversely, melatonin production usually stops in the morning when you open your eyes to the day's new light. But research shows that the production of melatonin climbs too high in folks who suffer from SAD. That excessive amount of the hormone results in a sedative effect upon the body. Many people with SAD suffer muscular aches and pains, along with headaches and a faltering immune system. Consequently, they often feel like they have the flu all winter long. Blue Lady More women than men suffer from SAD (and, apparently, depression in general), though the reason is unclear. According to Norman Rosenthal, MD, author of Winter Blues (Guilford Press), "about 6% of the US population may suffer from SAD, with an additional 14% suffering from subsyndromal [less severe] SAD." Because less sunlight reaches the northern latitudes, folks in Washington state and Alaska suffer the highest rates of SAD. People in sun-soaked Florida suffer the least. How do you escape SAD? If a winter vacation to the sunny South is out of the question for you, a natural program can brighten the wintry gray days and provide relief. Turn on the Light The most common treatment for SAD is light (also called phototherapy), which cuts back the body's manufacture of melatonin. Sitting in front of a special light box for about 30 minutes each morning during the winter months can often offset SAD. But the effects of this treatment vary from individual to individual, and some may be more sensitive to the light therapy than others. For artificial light treatment, consult an appropriately trained healthcare professional who can design a plan that finds the optimal intensity, length and time of day for the treatment that best works for you. Researchers at Columbia University have found that timing the light therapy with the nuances of a person's biological clock doubles its effectiveness (Archives of General Psychiatry 1/15/01). On the other hand, walking in natural light can banish these problems, and research finds that natural light frequently offers the best results (Journal of Affective Disorders 1996 Apr 12; 37(2-3):109-20). In this study, people either participated in a daily walk outdoors in natural light or were treated for half an hour in artificial light. At the end of the study, participants were tested for melatonin and cortisol (stress hormone) levels. Both were found to be lower after exposure to natural light than artificial light. Roll up those sleeves when you're outdoors this winter: Curiously enough, studies show that light produces physiological effects by being absorbed through both the eyes and the skin. Research now shows that light on the skin alters the hemoglobin in the blood. "This research suggests that SAD might be a disorder of the blood rather than a brain disorder," says Dan A. Oren, MD, of the Yale University School of Medicine (Science 1/12/98). Vitamin D Need If you suffer from seasonal depression, you may also not be getting enough vitamin D. During the sun-reduced winter months, stores of this fat-soluble vitamin drop, since the skin makes it when exposed to sunlight. When you step out into daylight, the sebaceous glands near the surface of your body produce an oily substance from cholesterol that rises to the skin's surface. Then, ultraviolet B rays from the sun convert this oily substance (7-dehydrocholesterol) into what is called previtamin D3. Finally, body heat converts previtamin D3 into vitamin D3 (a form of vitamin D). Twenty minutes of daily sunlight exposure on the hands, arms and face can give adequate amounts of vitamin D to light-skinned people. Dark-skinned people may need longer exposure. Supplements can help: In one study, researchers found that people who took vitamin D had significant improvement in depression Scale scores (Journal of Nutrition, Health & Aging 1999; 3(1):5-7). As far as vitamin D production goes, you can never receive too much sunlight (although overexposure resulting in a burn is never a good idea). The body absorbs vitamin D from the skin as needed and never accepts more than is required. (If you take supplements, follow package directions so you don't get too much of a good thing.) Food sources of vitamin D include eggs, fortified milk, cod liver oil, salmon and other fish. Walk Away the Blues Research also shows that exercise can chase the winter blues and that a little bit of exertion goes a long way. Exercise physiologists at Duke University found that little as eight minutes of physical activity can improve your mood. Exercise stimulates the brain to produce endorphins, feel-good hormones that help reduce pain and depression. Physical activity can also increase serotonin levels, those neurotransmitters that brighten emotions. These two hormones work together to make you feel better: Serotonin improves the functioning of your mind while endorphins produce beneficial effects on your body. In one study, researchers reported that exercise increased vitality and improved mood even in cases of prolonged depression (Psychological Medicine 1998 Nov; 28(6):1359-64). To banish SAD, engage in an outdoor activity in natural light, or get active indoors under bright lights. As you can see, much of the research into low, wintry moods suggests that sun worshippers may have been right all along: Exposure in winter to our friendly, local neighborhood star offers impressive mood benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=318) The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease
Date:
June 09, 2005 05:22 PM
The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease Presented at the 2005 World Garlic Symposium
Many of the world’s top-level scientists gathered in Washington D.C. this week for the 2005 Garlic Symposium, entitled, “Significance of Garlic and its Constituents in Cancer and Cardiovascular Disease.” The conference provided current scientific information about the effect of garlic and its constituents on health and performance. The symposium was held at the Georgetown University Conference Center on April 9-11, 2005. “For the first time in seven years authorities in various fields of garlic research from all over the world to provide the latest updates, specifically regarding aged garlic extract and its actions in diseased states including heart disease and cancer,” commented Dr. Matthew Budoff, M.D. cardiovascular researcher at UCLA. “Garlic has been used medicinally for thousands of years in virtually all ancient cultures. Now, new metabolic roles for garlic are being proposed and there are many promising lines of research.” Presentation highlights included:
Effect of aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study that determined that the atherosclerotic plaque burden detected by electron beam tomography (EBT) changed significantly with the use of aged garlic extract, Patients in Dr. Budoff’s study were able to significantly lower their total cholesterol, blood pressure, homocysteine and LDL cholesterol oxidation levels with aged garlic extract supplementation.
“Garlic is turning out to be a major player in cancer and heart disease prevention and control, especially in combination with drug treatments,” said Richard Rivlin, M.D. of Strang Cancer Prevention Center at Cornell. “It’s also showing us that we can start early. It’s madness to treat cancer and heart disease in their advanced stages. We need to start early and aged garlic extract is an excellent way to do that.” Almost 400 scientific studies have been completed on aged garlic extract, done in major universities worldwide. These studies have focused on a variety of heart disease risk factors such as cholesterol, high blood pressure, homocysteine levels, inhibiting LDL oxidation, anti-platelet aggregation and adhesion, stimulating blood circulation; in addition to other studies on immune stimulation, cognitive effects, liver function and anti-tumor effects. . Abstracts PRECLINICAL PERSPECTIVE ON GARLIC AND CANCER. John A. Milner, National Cancer Institute, Rockville, MD 20892 Mounting evidence points to the anticancer properties of fresh garlic extracts, aged garlic, garlic oil, and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis. A block in carcinogen activation through modulation of cytochrome P450-dependent monooxygenases and/or acceleration of carcinogen detoxification via induction of phase II enzymes likely account for some of this protection. The block in preneoplastic lesions and/or tumors in several sites suggests a generalizable mechanism. The efficacy of water- and lipid-soluble allyl sulfur compounds against chemical carcinogenesis appears comparable, although more studies are needed. A shift in sulfhydryl groups, redox status or enzyme catalysis may account for some of the phenotypic changes. They may also account for the observed hyperphosphorylation of specific cell cycle related proteins and histone hyperacetylation; both of which have been correlated with suppressed tumor cell proliferation. Several forms of allyl sulfur compounds are effective in blocking cell division and inducing apoptosis, but notable differences in the efficacy among these various compounds and across tumor types are evident. While the expression of many genes and proteins can be influenced by allyl sulfides; the challenge is to determine which is responsible for a phenotypic change. Additional studies are needed with more modest exposures and over prolonged periods and that utilize transgenic and knockout models to assist in the identification of molecular targets. Finally, additional research is needed to identify sensitive “effect” and “susceptibility” biomarkers that can ultimately be used to identify responders from non-responders. INHIBITION OF CORONARY ARTERIAL PLAQUE ACCUMULATION BY GARLIC. Matthew Budoff, Harbor-UCLA Medical Center, UCLA School of Medicine, California, USA Effect of Aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study to determine whether the atherosclerotic plaque burden detected by electron beam tomography (EBT) will change at a different rate under the influence of AGE or placebo. EBT can non-invasively quantitate the amount of coronary calcification and track atherosclerotic plaque over time. Nineteen of 23 patients completed the study protocol. The patients were well matched for age, gender, statin use and cardiac risk factors. Patients underwent EBT and blood testing at baseline, and then again after 12 months of randomization. The average change in the calcium score (Volumetric method) ± SD for the AGE group (n = 9) was 7.5 ± 9.4% over the one year. The placebo group (n = 10) demonstrated 22.2 ± 18.5% annual progression, significantly greater than the treated cohort (p = 0.01). While there were no significant changes in cholesterol parameters, or C Reactive protein between the groups, high density lipoproteins and plasma homocysteine in the AGE group demonstrated a trend toward improvement compared to the placebo patients. Thus, although this is a small-Scale trial, it demonstrates the potential of AGE to inhibit the rate of atherosclerosis (progression of coronary calcium), as compared to placebo over one year. Larger studies need to be performed to assess this potential anti-atherosclerotic therapy and the impact on coronary events. INFLUENCE OF GARLIC ON ENDOTHELIAL DYSFUNCTION IN HYPERHOMOCYSTEINEMIA. N. Weiss, N. Ide, T. Abahji, L. Nill, C. Keller, U. Hoffmann. Klinikum der Universität München, D-80336 Munich, Germany Endothelial dysfunction (ED) due to decreased bioavailable nitric oxide (NO) by increased vascular oxidant stress plays a critical role in the vascular pathobiology of hyperhomocysteinemia (hhcy). Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. We performed a placebo-controlled, blinded, cross-over study to examine whether AGE prevents macro- and microvascular ED during acute hhcy induced by an oral methionine challenge in healthy subjects. Acute hhcy leads to a significant decrease in flow-mediated vasodilation of the brachial artery as determined by vascular ultrasound, indicative of macrovascular ED, as well as a decreased number of recruited nailfold capillaries during postischemic reactive hyperemia as determined by videomicroscopy, and to a decreased ratio of acetylcholine (endothelium-dependent) vs. sodium nitroprusside (endothelium-independent) iontophoresis induced skin perfusion as measured by laser doppler flowmetry, indicative of microvascular ED. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute hhcy on endothelium-dependent brachial artery vasodilation and on acetylcholine-induced stimulation of skin perfusion. Whether or not this is accompanied by changes in biochemical parameters of ED is still under investigation. It is concluded that AGE may at least partly prevent a decrease in bioavailable NO during acute hhcy.
Bibliographies David Heber, MD, PhD, FACP, FACN Professor, UCLA Department of Medicine - Division of Clinical Nutrition, at the David Geffen School of Medicine, UCLA, and UCLA School of Public Health; Director, UCLA Center for Human Nutrition; Director, NIH Center for Dietary Supplement Research in Botanicals (CDSRB); Director, NCI-funded Clinical Nutrition Research Unit; Vice Chair, UCLA Collaborative Centers for Integrative Medicine; Member, UCLA's Jonsson Comprehensive Cancer Center Matthew Budoff, MD, FACC Matthew Budoff, MD, FACC, is an associate professor of medicine at the UCLA School of Medicine and program director for the Division of Cardiology, as well as director of the Electron Beam CT Laboratory at Harbor-UCLA Medical Center in Torrance, Calif. He completed his undergraduate work at University of California, Riverside, and earned his medical degree at George Washington University in Washington D.C. Dr. Budoff’s efforts to identify and modify risk factors for cardiovascular disease using electron beam CT have been extensively published. His latest research focuses on the progression of arteriosclerosis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=257) Phase 2 Carbohydrate Blocker from Source Naturals ...
Date:
June 01, 2005 09:37 AM
Source Naturals Phase 2® CARBOHYDRATE BLOCKER allows you to enjoy the foods you love without the calories! It’s a clinically proven, non-stimulant, all-natural nutritional ingredient that "neutralizes" all the digestive enzyme alpha amylase before it can convert starch into glucose and then fat. Essentially, it allows foods such as potatoes, breads, pasta, rice, corn and crackers (carbohydrates) to pass through the system with less caloric intake. Derived from the white kidney bean, it’s the first nutritional ingredient that has been clinically and scientifically proven to neutralize starch. Weight Control Is Acute Health Concern Excess weight is the number one cause of death in the United States–with more than 300,000 lives lost per year. Statistics confirm 110 million overweight Americans, of whom 39 million are more than 30 pounds overweight. The number of overweight individuals has grown by epidemic proportions in the Western world and the trend is a grave one. According to Journal of American Medical Association research, during the past ten years overweight Americans have increased by 65 percent. And a new risk group is comprised of “fast-food-loving” children, of whom one in three now tips the Scales at "overweight." Weight Loss Is An Uphill Battle One thing we know for certain about weight management is that for many people it becomes a lifetime struggle. And when these individuals lose weight, they more often than not gain it back. In fact, once off their diet, people rebound and put on an additional 10 percent, ending up heavier than before. One major “offender” when it comes to weight issues is the impact of carbohydrate consumption. Why do we gain weight when we eat carbohydrates? Complex carbohydrates are digested by alpha amylase, which breaks them down, principally as glucose. This glucose is then stored as energy or fat. It was theorized that a product that could block this activity would reduce the amount of carbohydrates converted to glucose. People balk at dramatic changes in lifestyle, no matter how many times your doctor may say “the best way to lose weight is to push yourself away from the table." So the goal is to identify a convenient way to cut down on caloric consumption, principally carbohydrates. Powerful Starch Control CARBOHYDRATE BLOCKER supports the dieter's quest for a healthy and simple weight loss when used in conjunction with the Maximum Metabolism Weight Loss Plan™. Several clinical studies have shown it to be effective in weight management. Carbohydrates (common foods such as pasta, bread, baked goods, rice, grains and potatoes) are high in calories. And a typical Western diet gets half its daily caloric intake from starch. CARBOHYDRATE BLOCKER is available in tablets or tasty, fruit-flavored, chewable wafers. Both contain Phase 2 (Formerly Phaseolamin 2250™), a highly refined derivative of white kidney beans. CARBOHYDRATE BLOCKER works by inhibiting alpha amylase, an enzyme that breaks down starch into glucose so that it can be absorbed in the body, thus decreasing caloric intake. With CARBOHYDRATE BLOCKER, undigested starch may pass through the body unabsorbed. Taken just before meals, CARBOHYDRATE BLOCKER may limit the conversion of carbohydrate calories to glucose. CARBOHYDRATE BLOCKER is manufactured through a proprietary process and studies prove that it’s safe and easy to use. The studies indicate that there is no effect on the digestion and absorption of other foodstuffs, namely protein.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=128) Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
Date:
May 24, 2005 09:52 AM
Cognitive Improvement in Mild to Moderate Alzheimer's Dementia After Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Maria De Jesus Moreno Moreno, MD Instituto Nacional de la Senectud, Mexico City, Mexico
in both men and woman they consistently improved after 90 and 180 days versus baseline with adiministration of GPC three times a day, whereas in the placebo group they remained unchanged or worsened. Statistically significant differences were observed between treatments after 90 and 180 days. Keypoints: references: Bartus RT, Dean RL III, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction, Science. 1982;217:408-414. 2. Larson EB, Kukull WA, Katzman RL. Cognitive impairment: Dementia and Alzheimer's disease. Annu Rev Public Health. 1992;13:431-449. 3. Hofman A, Rocca WA, Brayne C, et al, for the European Prevalence Research Group. The prevalence of dementia in Europe: A collaborative study of 1980-1990 findings. Int d Epidemiol. 1991;20:736-748. 4. Blackwood W, Corsellis JAN, eds. Greenfield's Neuropathology. 3rd ed. London: Arnold; 1976. 5. Geldmacher DS. Cost-effective recognition and diagnosis of dementia. 5emin Neurol. 2002;22:63-70. 6. Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459. 7. Perry EK. The cholinergic hypothesis--ten years on. Br Med Bull. 1986;42:63-69. 8. Giacobini E. From molecular structure to Alzheimer therapy. Jpn d Pharmacol. 1997;74:225-241. 9. Giacobini E. Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: From tacrine to future applications. Neurochem Int. 1998;32:413-419. 10. Brinkman SD, Smith RC, Meyer JS, et al. Lecithin and memory training in suspected Alzheimer's disease. J Gerontol. 1982;37:4-9. 11. Davis E, Emmerling MR, Jaen JC, et al. Therapeutic intervention in dementia. Crit Rev Neurobiol. 1993;7:41-83. 12. Amenta E Parnetti L, Gallai V, Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropiate approaches? Mech Ageing Dev. 2001;122:2025-2040. 13. Sigala S, Imperato A, Rizzonelli P, et al. k-Alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eurd Pharmacol. 1992;211:351-358. 14. Govoni S, Battaini E Lucchi L, et al. Effects of alpha-glycerylphosphorylcholine in counteracting drug-induced amnesia: Through cholinergic and non-cholinergic mechanisms [in Italian]. Basi Raz Ter. 1991;21:75-78. 15. Canonico PL, Nicoletti F, Scapagnini U. Neurochemical and behavioral effects of alpha-glycerylphosphorylcholine [in Italian]. Basi Raz Te~ 1990;20: 53-54. 191 CLINICAL THERAPEUTICS ® 16. Parnetti L, Amenta E Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: An analysis of published clinical data. Mech Ageing Dev. 2001;122:2041-2055. 17. Venn RD. The Sandoz Clinical Assessment-Geriatric (SCAG) Scale. A general-purpose psychogeriatric rating Scale. Gerontology. 1983;29:185-198. 18. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991;19:330-341. 19. Frattola L, Piolti R, Bassi S, et al. Multicenter clinical comparison of the effects of choline alphoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia. Curt Ther Res Clin Exp. 1991;49:683-693. 20. Muratorio A, Bonuccelli U, Nuti A, et al. A neurotropic approach to the treatment of multi-infarct dementia using L-c~-glycerylphosphorylcholine. Curt Ther Res Clin Exp. 1992;52:741-75l. 21. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: APA; 1994. 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. 23. Folstein ME Folstein SE. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198. 24. Loeb C, Gandolfo C. Diagnostic evaluation of degenerative and vascular dementia. Stroke. 1983;14:399-401. 25. Hamilton M. A rating Scale for depression.J Neurol Neurosurg Psychiatry. 1960;23:56-62. 26. Hamilton M. Development of a rating Scale for primary depressive illness. BrJ Soc Clin Psych& 1967;6:278-296. 27. Rosen WG, Mohs RC, Davis KL. A new rating Scale for Alzheimer's disease. AmJ Psychiatry. 1984;141:1356-1364. 28. Reisberg B, Ferris SH, De Leon MJ, et al. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry. 1982;139:1136-1139. 29. National Institute of Mental Health. Clinical global impressions. In: Guy W, ed. ECDEU Assessment for Psychopharmacology. Revised edition. Rockville, Md: National Institute of Mental Health; 1976:217-222. 30. Burns A, Russell E, Page S. New drugs for Alzheimer's disease. Br J Psychiatry. 1999;174:476-479. 31. Kumar V, Anand R, Messina J, et al. An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors. Eur J Neurol. 2000;7:159-169. 32. Knapp MJ, Knopman DS, Solomon PR, et al, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991. 192 M. Moreno 33. Lindstrom MJ, Bates DM. Newton-Rapshon algorithms for linear-mixed effects models for repeated measure data. J Am Stat Assoc. 1998;83:1014-1022. 34. Thai LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology 1996;47:705-711. 35. Rogers SL, Friedhoff LT, for the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303. 36. Rogers SL, Doody RS, Mohs RC, Friedhoff LT, for the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158:1021-1031. 37. Corey-Bloom J, Anand R, Veach J, for the ENA 713 B352 Study Group. A randomized trial evaluating the efficacy and the safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1:55-65. 38. Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. BMJ. 1999;318: 633-638. 39. Amenta E Bronzetti E, Del Valle M, Vega JA. Effects of alpha-glycerylphosphorylcholine in neuroanatomy of aging brain in experimental animals [in Italian]. Basi Raz Te~: 1990;20:31-38. Address correspondence to: Scientific Department, Italfarmaco SpA, via dei Lavoratori 54, 20092 Cinisello Balsamo, Milan, Italy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=98) Garlic for Treating Hypercholesterolemia - A Meta-Analysis ...
Date:
May 12, 2005 12:44 PM
Garlic for Treating Hypercholesterolemia - A Meta-Analysis of Randomized Clinical Trials
DATA SOURCES: Systematic literature searches were conducted on the MEDLINE, EMBASE, BIOSIS, Cochrane Library, AMED, and CISCOM databases. Manufacturers of commercial garlic preparations and experts in the field were asked about published or unpublished trials.
STUDY SELECTION: Selected trials were required to state that they were randomized, double-blind, and placebo-controlled; use garlic monopreparations; include persons with mean total cholesterol levels of at least 5.17 mmol/L (200 mg/dL); and report total cholesterol level as an end point. There were no language restrictions.
DATA EXTRACTION: Two reviewers, blinded to key identifiers of each paper, independently extracted data in a standardized manner and assessed methodologic quality by using the Jadad Scale. Discrepancies were settled through discussion.
DATA SYNTHESIS: In the 13 trials included in the meta-analysis, garlic reduced total cholesterol level from baseline significantly more than placebo (P < 0.01); the weighted mean difference was -0.41 mmol/L (95% CI, -0.66 to -0.15 mmol/L) (-15.7 mg/dL [CI, -25.6 to -5.7 mg/dL]). Six diet-controlled trials with the highest scores for methodologic quality revealed a nonsignificant difference between garlic and placebo groups; the weighted mean difference was -0.11 mmol/L (CI, -0.30 to 0.08 mmol/L) (-4.3 mg/dL [CI, -11.7 to 3.1 mg/dL]).
CONCLUSIONS: The available data suggest that garlic is superior to placebo in reducing total cholesterol levels. However, the size of the effect is modest and the robustness of the effect is debatable. The use of garlic for hypercholesterolemia is therefore of questionable value.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=38) Study Says Supplements Could Save Billions in Health Care Costs
Date:
May 09, 2005 05:52 PM
Study Says Supplements Could Save Billions in Health Care CostsA study released at a House subcommittee hearing in late September on the cost savings and health benefits of selected dietary supplements projected a $15 billion reduction in health care costs over a five-year period from calcium and folic acid. The study, commissioned by the Dietary Supplement Education Alliance (DSEA) and conducted by the Lewin Group, found that the five selected supplements—omega-3 fatty acids, glucosamine, and saw palmetto along with calcium and folic acid—could make a significant impact on health care costs while positively affecting consumers’ health status. DSEA asked the Lewin Group to put a dollar figure on the benefits of calcium and folic acid because the Food and Drug Administration (FDA) allows health claims on products containing these nutrients. Since the study began, FDA also authorized qualified health claims on omega-3s, and the National Institutes of Health has implemented large-Scale studies of saw palmetto and glucosamine. “Many industry experts have long believed that dietary supplements provide consumers with long-term health benefits by reducing the incidence of debilitating health problems, and this study proves it,” said Elliott Balbert, president and CEO of Natrol, Inc. (Chatsworth, CA) and president of DSEA. “The findings provide evidence to support both the cost savings and quality-of-life benefits of these particular supplements.” DSEA commissioned the Lewin Group to critically review the research literature on the five supplements for consistency, validity, and impact (i.e., size of the effect; to develop estimates of the potential health care expenditure savings that could result from daily use of two of the supplements; and to suggest areas of future research for supplements where there is emerging evidence. The Lewin Group arrived at the $15 billion figure by focusing on two specific health issues: hip fractures (including hospital and nursing facility expenses) in the case of calcium along with vitamin D, and neural tube defects in the case of folic acid. Joan DaVonzo, vice president of the Lewin Group, said at a news teleconference following the Sept. 22 hearing that the savings in health care costs from supplementing calcium intake might be even larger than the projected $13.9 billion if other types of fractures were included. Dr. Jeffrey Blumberg, professor of nutrition at Tufts University and one of the witnesses who testified before the House Subcommittee on Human Rights & Wellness chaired by Rep. Dan Burton (R-IN), told reporters the health benefits—and potential cost savings—of folic acid supplementation went far beyond the $1.1 billion estimate for neural tube defects. He said folic acid has been shown to help prevent other types of birth defects as well as reducing the risk of cardiovascular disease and certain types of cancer. “It’s not a one nutrient/one disease relationship,” Blumberg said. “Research shows that the typical American diet does not always provide a sufficient level of nutrients. This study just reveals the tip of the iceberg in the ability of supplements to contribute to a healthier America,” said Elwood Richard, president and founder of supplement manufacturer NOW Foods (Bloomingdale, IL), in response to the study. DaVonzo acknowledged that the potential for the five supplements studied went beyond the dollar figures projected in the study. For instance, in the case of saw palmetto and its reported prostate health benefits, “The impact could be huge,” she said. “It’s no surprise to anyone in the industry that dietary supplements are safe, affordable, and effective, and this study not only confirms that statement, but will, more importantly, reach an audience well beyond industry,” said David Seckman, executive director and CEO of the National Nutritional Foods Association. “An even more critical finding is the fact that dietary supplements can dramatically cut health care costs if used regularly—a point that won’t be lost on any American consumer, the media, and lawmakers aware of the staggering—and rising—cost of health care in this country.” To help spread the message beyond the halls of Congress, DSEA prepared an audio news release and was organizing a satellite media tour. DSEA vice chairman Jon Benninger said the hope was to commission followup studies on other nutrients “as funding allows.” Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/
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