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NSAIDs vs. Curcumin: Which One Relieves Joint Pain Without Stopping Healing?   
Date:
September 14, 2026 11:22 AM
Comparative Analysis of NSAIDs versus Curcumin in Musculoskeletal Tissue RepairPrimary Biological Mechanisms and Pharmacological TargetsManaging soft tissue and joint injuries presents a persistent therapeutic challenge in musculoskeletal medicine. Acute inflammation triggers pain, localized swelling, and mechanical disability, which routinely drives patients toward pharmacological relief. For decades, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, celecoxib, and diclofenac have served as primary clinical interventions. While these synthetic agents effectively extinguish acute pain signals, expanding cellular and clinical research indicates that their biochemical mechanism interrupts the fundamental repair cascades required for long-term connective tissue healing. In contrast, curcumin - a natural polyphenolic compound derived from the rhizomes of Curcuma longa (turmeric) - exhibits a distinct, multi-targeted regulatory profile that calms hyperactive inflammation while protecting the structural components of cartilage and tendon tissue.The functional divergence between these two compounds becomes clear when considering an intuitive mechanical analogy. Tissue trauma resembles damage to a commercial building, where initial inflammation functions as the construction and demolition crew tasked with clearing rubble, stabilizing the foundation, and laying down fresh structural framing. NSAIDs function like abruptly cutting electrical power to the entire work site: the noisy machinery stops instantly and the immediate disturbance ceases, but the construction workers lose the power necessary to clean the debris and erect permanent walls. Conversely, curcumin operates as an experienced site manager: it silences unnecessary chaos and prevents site vandalism while ensuring that the skilled workers - specifically chondrocytes in cartilage and tenocytes in tendons - remain fully active, supplied, and capable of completing the restoration. At the cellular level, NSAIDs exert their effects through the catalytic inhibition of cyclooxygenase enzymes, categorized as constitutive cyclooxygenase-1 (COX-1) and inducible cyclooxygenase-2 (COX-2). Membrane phospholipids damaged during injury release arachidonic acid, which COX enzymes convert into pro-inflammatory lipid mediators known as prostanoids, most notably prostaglandin E2 (PGE2). Nonselective NSAIDs block both isoforms, while selective coxibs specifically target COX-2. By shutting off PGE2 production, NSAIDs rapidly elevate pain thresholds and blunt localized swelling. However, because PGE2 also functions as a vital signaling cue for cellular recruitment, angiogenesis, and cellular proliferation, this total enzymatic shutdown strips local repair cells of the baseline signals required to orchestrate tissue regeneration. Curcumin avoids this indiscriminate pathway paralysis by acting upstream on master transcriptional control switches rather than directly neutralizing isolated enzymes. Its primary therapeutic mechanism centers on the inhibition of Nuclear Factor-kappa B (NF-kB) and Activator Protein-1 (AP-1) signaling networks. Under acute stress or chronic inflammatory loads, the NF-kB protein complex is released from its cytoplasmic inhibitor, IkBa, and translocates directly into the cell nucleus, where it drives the transcription of catabolic cytokines such as interleukin-1 beta (IL-1ß), tumor necrosis factor-alpha (TNF-a), and interleukin-6 (IL-6). Curcumin blocks the phosphorylation and degradation of IkBa, effectively keeping NF-kB trapped in the cytoplasm. By preventing this nuclear entry, curcumin attenuates the expression of pro-inflammatory cytokines and downstream matrix-degrading enzymes while preserving baseline physiological functions. Furthermore, curcumin activates the nuclear factor erythroid 2-related factor 2 (Nrf2) and antioxidant response element (ARE) pathways, which upregulate endogenous cellular antioxidants to neutralize destructive reactive oxygen species (ROS) that induce cell death in injured joints.
The Mechanisms of NSAID-Induced Inhibition in Cartilage and Tendon RepairArticular cartilage and tendons are specialized, bradytrophic connective tissues characterized by relatively low basal metabolic rates and limited endogenous vascular supplies. These physical constraints make their cellular maintenance highly vulnerable to pharmaceutical disruptions. When synthetic compounds impair cell migration, survival, or extracellular matrix secretion, the intrinsic repair capacity of these structures is substantially degraded.Cartilage maintenance depends on chondrocytes, the sole cell type residing within articular joints, which are responsible for generating and maintaining the extracellular matrix of Type II collagen and water-binding proteoglycans such as aggrecan. Because adult articular cartilage lacks a direct vascular network, major defect repair relies heavily on the recruitment and chondrogenic differentiation of subchondral mesenchymal stem cells (MSCs) through endochondral ossification. Experimental evaluations demonstrate that systemic or intra-articular NSAID exposure halts this regenerative differentiation. Both nonselective NSAIDs and selective COX-2 inhibitors interfere with chondrocyte maturation and prevent successful tissue integration following cartilage transplantation or microfracture procedures. At the cellular level, common NSAIDs - including indomethacin, ketorolac, and diclofenac - induce cell cycle arrest in chondrocytes by blocking transition from the resting G0 phase to the proliferative G1. phase, substantially reducing viable cell numbers. Concurrently, NSAIDs downregulate Bone Morphogenetic Protein-2 (BMP-2), an essential anabolic signaling molecule that orchestrates matrix synthesis. Histological analyses in animal models reveal that NSAID administration causes a marked loss of extracellular proteoglycan content and widespread chondrocyte depletion, yielding elevated modified Mankin scores that signify advanced structural degeneration. In layman's terms, proteoglycans serve as water-absorbing structural sponges that grant cartilage its elastic shock absorption. When NSAIDs deplete these molecules, the joint surface dries out, becomes brittle, and rapidly wears down under routine mechanical friction. Tendon healing is similarly susceptible to disruption by NSAIDs. Tendons operate as high-tensile structural cables composed of longitudinally arranged Type I collagen fibers, maintained by specialized fibroblasts termed tenocytes and tenoblasts. Healing after acute rupture or chronic tear progresses through an initial inflammatory phase, followed by a proliferative phase of cell migration, and culminates in a lengthy remodeling phase of collagen alignment. In vitro and in vivo studies establish that NSAIDs directly suppress the migration and proliferative capacity of tenocytes during the critical early healing window. Without an adequate cellular workforce migrating into the wound bed, provisional collagen scaffolding cannot be synthesized effectively. The disruption is particularly pronounced at the enthesis, the specialized fibrocartilaginous junction where soft tendon inserts into rigid bone. Re-establishing this transition zone requires coordinated bone remodeling and chondrogenic differentiation, both of which are hindered by COX inhibition. In animal rotator cuff repair models, early administration of NSAIDs significantly delays collagen fiber organization and impairs mechanical integration at the insertion site, resulting in a measurable decline in load-to-failure strength and overall tendon toughness. Furthermore, while prolonged inflammation contributes to pathological degeneration, the transient synthesis of PGE2 during the initial hours following injury is essential for regulating localized microvascular flow and hyperemic nutrient delivery. By eliminating this early prostanoid pulse, NSAIDs starve the repair zone of oxygen and circulating factors precisely when the cellular metabolic demand is highest. Beyond direct biochemical cytotoxicity, systemic NSAIDs introduce a physical hazard known as analgesic arthropathy. In musculoskeletal biomechanics, pain functions as a protective feedback mechanism, forcing the patient to unload an injured joint or limb to prevent structural overload. By effectively blunting the pain reflex while simultaneously undermining the cellular synthesis of proteoglycans and collagen, NSAIDs create a deceptive state of perceived recovery. Patients prematurely resume unrestricted weight-bearing and strenuous activity, placing substantial, uncompensated mechanical forces onto compromised cartilage surfaces and unhealed tendon fibers. Over time, this recurring mechanical trauma accelerates joint space narrowing, promotes microfractures in the subchondral plate, and hastens functional joint breakdown. Chondroprotective and Tenogenic Mechanisms of CurcuminIn sharp contrast to the suppressive actions of synthetic COX inhibitors, curcumin exhibits a tissue-sparing, pro-regenerative biological profile. Rather than paralyzing cellular metabolism, curcumin modulates the microenvironment by suppressing destructive catabolic enzymes while supporting the baseline anabolic signals required for cartilage and tendon reconstruction.In articular cartilage, curcumin acts as a direct chondroprotective agent by dismantling the catabolic cascade induced by pro-inflammatory cytokines. When joint tissues are exposed to elevated IL-1ß and TNF-a, chondrocytes are provoked to synthesize matrix metalloproteinases - specifically collagenases such as MMP-1, MMP-3, and MMP-13 - along with aggrecanases like ADAMTS5. These enzymes function like enzymatic shears, systematically slicing through structural Type II collagen strands and degrading aggrecan cores. Curcumin suppresses the transcription and secretion of MMP-1, MMP-3, MMP-13, and ADAMTS5 by neutralizing NF-kB and AP-1 activation. Concurrently, it upregulates Cbp/p300 Interacting Transactivator with ED-rich tail 2 (CITED2), an essential transcriptional regulator that represses matrix metalloproteinases at the genomic level. In addition to halting extracellular degradation, curcumin protects chondrocytes from inflammatory apoptosis. Exposure to oxidative stress and inflammatory cytokines typically triggers programmed cell death by activating the intrinsic caspase cascade. Curcumin suppresses this apoptotic pathway by reducing the cleavage of executioner caspase-3, downregulating the pro-apoptotic factor Bax, and elevating anti-apoptotic Bcl-2 expression. Microscopic and histological analyses of osteoarthritic cartilage treated with curcumin consistently show robust Safranin O staining, intact surface regularity, preserved chondrocyte density, and significantly reduced Osteoarthritis Research Society International (OARSI) degradation scores. Within tendon biology, curcumin promotes active tissue regeneration (tenogenesis) rather than inert scar formation. In animal models of tendon rupture and surgical repair, curcumin guides tendon-derived stem and progenitor cells (TSPCs) toward mature tenocyte differentiation. This lineage-specific differentiation is orchestrated primarily through activation of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) and Wnt/ß-catenin signaling cascades. As stem cells commit to the tenogenic pathway, they significantly upregulate crucial structural and phenotypic markers, including epithelial cell adhesion molecule (EpCAM), tenomodulin, and the master tendon transcription factor Scleraxis. Through this guided differentiation, curcumin supports the preferential synthesis and organized deposition of high-tensile Type I collagen fibers, the primary architectural building blocks of healthy tendons. Injured tendons typically fill with disorganized, loose Type III collagen, which forms a structurally inferior, compliant scar. Curcumin supplementation promotes the progressive maturation from primitive Type III collagen to densely packed, parallel Type I collagen fibrils, restoring native tensile strength and mechanical breaking force. A major clinical challenge following tendon surgery is the development of peritendinous adhesions, in which excessive fibrotic scar tissue binds the healing tendon to its synovial sheath, restricting range of motion and joint gliding. Postoperative tendon repair involves a balance between extrinsic healing (in which exterior fibroblasts infiltrate the defect and deposit messy scar tissue) and intrinsic healing (in which tenocytes within the tendon substance reconstruct the matrix). Curcumin suppresses excessive peritendinous inflammation and extrinsic fibrosis while accelerating intrinsic tenocyte repair. Biomechanical testing confirms that local or systemic curcumin administration yields lower adhesion scores, increased gliding distances, and superior functional mobility without sacrificing structural load-bearing capacity. Comparative Clinical Efficacy and Systemic Safety ProfilesTranslating cellular findings into clinical practice requires weighing therapeutic outcomes against systemic safety profiles. While synthetic NSAIDs deliver potent, rapid analgesia during acute musculoskeletal pain events, their chronic administration is constrained by systemic toxicities across multiple organ systems.In randomized, active-controlled clinical trials of knee osteoarthritis, optimized curcumin preparations have demonstrated clinical pain reduction and functional recovery comparable to standard therapeutic doses of NSAIDs. In a randomized, open-label parallel-arm study evaluating 139 patients with symptomatic knee osteoarthritis, subjects received either 500 mg of a bio-enhanced curcumin extract three times daily or 50 mg of diclofenac sodium twice daily for 28 consecutive days. Patients treated with curcumin demonstrated comparable improvements in pain intensity on the Visual Analogue Scale (VAS) and functional scores on the Knee Injury and Osteoarthritis Outcome Score (KOOS) at days 14 and 28, showing no statistically significant difference in therapeutic efficacy compared to diclofenac. However, the systemic tolerability profiles between the treatments diverged markedly. Overall adverse events occurred in only 13% of the curcumin group compared to 38% of the diclofenac cohort. In the diclofenac arm, 28% of patients developed dyspeptic symptoms severe enough to require concurrent treatment with H2-receptor antagonists or proton pump inhibitors to prevent mucosal ulceration, whereas no patients in the curcumin cohort required gastroprotective intervention. Furthermore, the curcumin cohort experienced a significant reduction in flatulence and digestive discomfort, demonstrating beneficial gastric and intestinal cytoprotective effects. These safety observations are consistent across broader systematic reviews and meta-analyses. Nonsteroidal anti-inflammatory agents inherently compromise gastrointestinal integrity by systematically depleting cytoprotective prostaglandins, leaving the gastric epithelium vulnerable to acid erosion and hemorrhage. In addition, systemic inhibition of renal and vascular COX enzymes by NSAIDs reduces renal perfusion and disrupts the balance between prostacyclin and thromboxane, elevating the risk of fluid retention, hypertension, and adverse cardiovascular thrombotic events. Curcumin does not suppress these physiological prostanoid pathways, making it free from ulcerogenic, nephrotoxic, and cardiotoxic properties at therapeutic dosages.
A longstanding limitation of standard curcumin supplementation in clinical settings has been its low oral bioavailability. Native curcuminoids are highly lipophilic, poorly soluble in aqueous gastric fluids, and subject to rapid hepatic and intestinal phase II metabolism into inactive glucuronides and sulfates, leading to swift biliary and fecal excretion. Consequently, raw culinary turmeric powders struggle to achieve the therapeutic systemic circulating concentrations required to reach poorly vascularized joint and tendon compartments. Modern pharmacognosy has addressed this pharmacodynamic hurdle through advanced delivery formulations. Modern strategies - such as co-administration with the natural alkaloid piperine (which inhibits hepatic glucuronidation), micellar dispersions, phytosomal phospholipid complexes, and bio-enhanced submicron dispersions - elevate systemic blood bioavailability by ten- to thirty-fold compared to unformulated extracts. These modern delivery platforms ensure that therapeutic concentrations reach synovial fluid, subchondral bone, and fibrous tendon sheaths without requiring excessive oral dosing. Conclusions and Translational Clinical ImplicationsThe biological and clinical evidence reveals distinct physiological paths for NSAIDs and curcumin in orthopedic recovery. While NSAIDs remain powerful tools for the brief alleviation of acute, unmanageable pain, their ongoing administration during active tissue healing presents substantial biological compromises. Tendons and cartilage require a controlled, transient inflammatory cascade to signal cell recruitment, stimulate stem cell differentiation, and direct extracellular matrix synthesis. By completely shutting down cyclooxygenase enzymes and depleting local prostaglandins, NSAIDs disrupt this regenerative cascade. The resulting cellular consequences - including chondrocyte cell cycle arrest, proteoglycan loss, suppression of tenocyte migration, and weakened collagen tensile strength at the tendon-to-bone interface - demonstrate that pain relief from NSAIDs frequently comes at the cost of the structural integrity of healing connective tissues.In contrast, curcumin provides a tissue-preserving alternative that decouples pain and inflammation control from cellular suppression. Operating upstream at the level of NF-kB and AP-1 transcriptional activation, curcumin attenuates the expression of pro-inflammatory cytokines while leaving the physiological baseline of cellular metabolism intact. In cartilage, it actively represses the matrix-degrading enzymes MMP-1, MMP-3, MMP-13, and ADAMTS5, maintains water-binding proteoglycan content, and protects chondrocytes from inflammatory apoptosis. In damaged tendons, curcumin stimulates tenogenic differentiation of local stem cells via PI3K/Akt signaling, supports the proper maturation of dense Type I collagen fibers, and prevents restrictive peritendinous scar adhesions, preserving both joint mobility and mechanical breaking strength. From a translational perspective, these findings indicate that clinical protocols should reconsider relying on continuous NSAIDs as the default intervention for connective tissue injuries, post-surgical recovery, and chronic degenerative conditions. Where synthetic NSAIDs are deemed necessary, their use should be confined to short-term acute flare-ups to avoid interrupting early tissue remodeling. For long-term joint preservation, ongoing tendinopathy rehabilitation, and chronic osteoarthritis management, optimized bio-enhanced curcumin formulations deliver pain relief and functional restoration comparable to conventional pharmaceuticals, all while preserving the biological processes required for lasting musculoskeletal repair. References: NSAID therapy effects on healing of bone, tendon, and the enthesis The Detrimental Effects of Systemic Ibuprofen Delivery on Tendon Conservative management of symptomatic knee osteoarthritis - PMC Positives and negatives of nonsteroidal anti-inflammatory drugs in (PDF) Conservative management of symptomatic knee osteoarthritis Non-steroidal anti-inflammatory drugs influence cartilage healing Is Curcumine Useful in the Treatment and Prevention of ... - PMC - NIH Efficacy and mechanisms of curcumin in the treatment of osteoarthritis Biological actions of curcumin on articular chondrocytes - PubMed Curcumin slows osteoarthritis progression and relieves ... - PMC - NIH Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Anti-inflammatory management for tendon injuries - friends or foes? The mechanistic role of curcumin on matrix metalloproteinases in Therapeutic effects of turmeric or curcumin extract on pain and Curcumin inhibits chondrocyte apoptosis and inflammation in ... - PMC Analysis of the mechanism of curcumin against osteoarthritis using Synergistic enhancement of tendon-to-bone healing via anti ... - PMC A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis A randomized, pilot study to assess the efficacy and safety ... - PubMed Effectiveness of curcuminoids in the treatment of knee osteoarthritis THE EFFECTS OF TRADITIONAL STRENGTHENING EXERCISES Putting Some Muscle into Osteoarthritis | Annals of Internal Medicine Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Calebin A, a Compound of Turmeric, Down-Regulates Inflammation The Effect of Non-Steroidal Anti-Inflammatory Drugs on Tendon-to Chiropractor in Toronto, ON, Canada :: Head and Neck Pain Investigation of the association of long-term NSAID use with ... - PMC Curcumin Improves Functional Recovery of Ruptured Tendon by Chemically modified curcumin (CMC2.24) alleviates osteoarthritis Curcumin improves age-related and surgically induced osteoarthritis (PDF) Curcumin Improves Functional Recovery of Ruptured Tendon Investigation of the effects of umbilical cord-derived mesenchymal Effect of curcumin-loaded polycaprolactone scaffold on Achilles Controlled release of curcumin from curcumin-loaded nanomicelles Efficacy and safety of combination of curcuminoid complex ... - PMC The efficacy of Curcuma Longa L. extract as an adjuvant therapy in
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6653) The Ultimate Guide to Cellular Longevity: NAD+, Methylation, and Senolytics 
Date:
September 10, 2026 10:57 AM
Introduction: Understanding Cellular Aging and Energy DeclineBiological aging represents a progressive decline in cellular maintenance, structural repair, and energy generation. Over decades, tissues experience an attrition of functional reserves, compromised stress resilience, and persistent low-grade systemic inflammation. At the cellular scale, biological degeneration is driven by a failure to generate bioenergetic fuel, repair genetic code, and clear metabolic waste.Cellular aging is characterized by interconnected biological disruptions known as the hallmarks of aging. These encompass genomic instability, epigenetic alterations, mitochondrial decay, loss of proteostasis, and cellular senescence. Rather than operating as isolated occurrences, these phenomena establish a self-reinforcing degenerative cycle: declining cellular power generation impairs enzymatic genetic repair, promoting the accumulation of damaged cells that enter irreversible growth arrest and poison surrounding healthy tissues. Mitigating cellular aging requires examining how microscopic bioenergetic pathways deteriorate and evaluating how targeted nutritional and biochemical interventions can restore cellular homeostasis. The Role of Mitochondria and ATP ProductionEvery biological function - from muscular contraction to continuous DNA replication - depends on adenosine triphosphate (ATP), the primary biochemical energy currency of living systems. Cells produce the vast majority of this energy within mitochondria through oxidative phosphorylation. Within these specialized organelles, metabolic intermediates derived from dietary carbohydrates and lipids donate high-energy electrons to the electron transport chain. The flow of these electrons across protein complexes establishes an electrochemical proton gradient across the inner mitochondrial membrane, driving ATP synthase to manufacture ATP.A youthful cell functions like an efficient municipal power grid, dynamically matching energetic demands with immediate ATP output. However, as biological aging progresses, mitochondrial efficiency declines. The electron transport chain becomes structurally leaky, inadvertently shedding electrons that react with ambient molecular oxygen to produce reactive oxygen species (ROS). While regulated levels of ROS participate in vital intracellular signaling, chronic excess induces widespread oxidative stress. Mitochondria are exceptionally vulnerable to this oxidative burden because they carry their own circular genetic material, known as mitochondrial DNA (mtDNA). Unlike nuclear DNA, mtDNA lacks the protective shielding of histone proteins and possesses rudimentary repair systems. As a result, mtDNA sustains cumulative oxidative damage, encoding increasingly defective electron transport chain proteins. This dynamic generates a bioenergetic deficit: degraded mitochondria synthesize progressively less ATP while emitting greater volumes of damaging free radicals. Deprived of optimal ATP reserves, cells lack the energy necessary to drive vital enzymatic repair cascades, accelerating structural degeneration and functional exhaustion. How Cellular Senescence Accelerates the Aging ProcessWhen healthy cells confront critical physiological damage - such as severe telomere attrition, persistent DNA double-strand breaks, or oxidative stress - they activate protective cell cycle arrest pathways governed primarily by the p53/p21^CIP1 and p16^INK4a/Rb molecular checkpoints. This defensive shutdown, termed cellular senescence, permanently prevents the replication of potentially premalignant or mutated cells.Senescent cells, colloquially known as "zombie cells," enter a state of permanent growth arrest while actively resisting programmed cell death (apoptosis). Over time, these cells accumulate within adipose depots, skeletal muscle, the vascular endothelium, and major organs, largely because immune surveillance and clearance pathways simultaneously lose functional efficiency. The systemic danger of senescent cells stems from their secretome. Rather than remaining biologically inert, senescent cells develop a hyperactive secretory state termed the Senescence-Associated Secretory Phenotype (SASP). The SASP is a destructive mixture of pro-inflammatory cytokines, chemokines, extracellular matrix-degrading matrix metalloproteinases (MMPs), and reactive oxygen species. Through this toxic secretome, even a small burden of senescent cells can impair whole-tissue architecture. SASP factors degrade surrounding structural proteins, induce insulin resistance in neighboring metabolic cells, and biochemically force adjacent healthy cells into secondary senescence. This persistent paracrine signaling fuels chronic, sterile, low-grade systemic inflammation, termed "inflammaging," which accelerates systemic tissue degeneration and elevates susceptibility to degenerative age-related pathologies. Nicotinamide Riboside (NR) and the NAD+ Salvage PathwayThe Biochemistry of NAD+ Depletion Over TimeNicotinamide adenine dinucleotide (NAD+) is an indispensable coenzyme present in every living cell. NAD+ fulfills a dual biological mandate: it serves as a central redox cofactor that shuttles electrons between cellular metabolic reactions, and it functions as an obligatory consumable substrate for regulatory enzymes that preserve cellular viability. In its redox capacity, NAD+ accepts electrons to form NADH during glycolysis, the tricarboxylic acid (TCA) cycle, and fatty acid beta-oxidation, subsequently donating those electrons to Complex I of the respiratory chain to power ATP synthesis.
The primary enzymatic driver of age-related NAD+ destruction is CD38, a membrane-bound glycohydrolase expressed on immune cells that is upregulated in response to chronic SASP exposure. Concurrently, lifelong genotoxic damage causes persistent activation of Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that cleaves the glycosidic bonds of NAD+ to assemble branched poly(ADP-ribose) chains at DNA lesion sites. Because PARP-1 consumes NAD+ without directly recycling the molecule, chronic DNA damage depletes intracellular NAD+ pools, impairing bioenergetics and limiting sirtuin activity. How NR Efficiently Boosts Cellular NAD+ LevelsThe mammalian body maintains its NAD+ supply through three distinct biosynthetic routes: the de novo pathway from dietary L-tryptophan, the Preiss-Handler pathway from nicotinic acid (niacin), and the NAD+ Salvage Pathway. The de novo pathway requires substantial energy expenditure, consuming roughly sixty milligrams of dietary tryptophan to yield a single milligram of NAD+. The Preiss-Handler pathway, while effective, can induce cutaneous prostaglandin-mediated flushing at therapeutic intakes. Consequently, the salvage pathway serves as the primary mechanism for maintaining intracellular NAD+ pools.The salvage pathway recycles the breakdown product nicotinamide (NAM), which is released whenever NAD+-consuming enzymes execute their functions. Under normal conditions, cells convert free nicotinamide into nicotinamide mononucleotide (NMN) via the rate-limiting enzyme nicotinamide phosphoribosyltransferase (NAMPT), after which NMN adenylyltransferases (NMNAT1–3) complete the conversion into NAD+. However, NAMPT expression declines with advancing age, chronic inflammation, and metabolic stress, limiting the recycling capacity of the cell. Nicotinamide Riboside (NR) is a naturally occurring pyridine nucleoside that bypasses this enzymatic bottleneck. Upon cellular entry via equilibrative nucleoside transporters, NR is directly phosphorylated into NMN by nicotinamide riboside kinases (NRK1 and NRK2) using a single molecule of ATP. Because the NRK pathway remains intact and robust across the lifespan, NR provides an efficient alternative entry point into the NAD+ salvage cascade. Clinical evaluations in humans confirm the safety, bioavailability, and pharmacokinetics of oral NR supplementation. Randomized, double-blind, placebo-controlled trials reveal that oral NR chloride produces dose-dependent increases in steady-state whole blood NAD+ concentrations. Dosing regimens of 100 mg, 300 mg, and 1,000 mg daily elevate blood NAD+ levels by approximately 22%, 51%, and up to 142%, respectively, within two weeks of administration, maintaining these elevations throughout continuous use. High-resolution metabolomic analyses also demonstrate parallel elevations in nicotinic acid adenine dinucleotide (NAAD), establishing it as a reliable biomarker of active intracellular NAD+ synthesis without hepatic or systemic toxicity. Sirtuin Activation and DNA Repair MechanismsReplenishing intracellular NAD+ supports functions beyond mitochondrial ATP generation. NAD+ functions as an obligatory cofactor for sirtuins (SIRT1 through SIRT7), a family of class III histone and non-histone protein deacetylases that regulate stress resilience, metabolic homeostasis, and cell survival. Sirtuins couple the removal of acetyl groups from target lysine residues to the stoichiometric cleavage of NAD+, producing nicotinamide and O-acetyl-ADP-ribose. In states of NAD+ deficiency, sirtuin enzymes remain inactive regardless of cellular demand.In the nucleus, SIRT1 coordinates defense against cellular decline. When activated by restored NAD+ levels, SIRT1 deacetylates peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1a), the master transcriptional coactivator of mitochondrial biogenesis. This deacetylation stimulates mitochondrial replication and assembly, expanding functional respiratory capacity. Concurrently, SIRT1 deacetylates the p65 subunit of nuclear factor-kappa B (NF-kB), suppressing the transcription of pro-inflammatory cytokines. In the mitochondria, SIRT3 utilizes NAD+ to deacetylate metabolic enzymes and superoxide dismutase 2 (SOD2), enhancing the organelle's capacity to neutralize reactive oxygen species. At the same time, cellular NAD+ levels directly regulate genomic integrity through PARP-1. When genotoxic stress or oxidative damage induces single- or double-strand DNA breaks, PARP-1 binds to the damaged termini using its zinc-finger domains. Bound PARP-1 hydrolyzes NAD+ to synthesize extensive, negatively charged poly(ADP-ribose) polymers on itself and adjacent histones. This modification relaxes chromatin architecture and establishes an electrostatic scaffold that recruits base excision repair and homologous recombination complexes. Recent discoveries demonstrate close crosstalk between sirtuins and PARP-1 during DNA repair. PARP-1 recruits SIRT1 to double-strand breaks, where SIRT1 deacetylates the chromatin-remodeling ATPase BRG1 to displace nucleosomes and facilitate homologous recombination. However, because PARP-1 and SIRT1 draw from the same intracellular NAD+ pool, severe NAD+ depletion forces a biological compromise: PARP-1 consumes the scarce remaining cofactor to address DNA damage, leaving sirtuins deactivated. Restoring NAD+ via NR prevents this deficit, enabling concurrent genomic repair and sirtuin-mediated metabolic defense. Quercetin: A Powerful Senolytic and mTOR RegulatorClearing Senescent "Zombie" Cells from TissuesThe accumulation of senescent cells has driven interest in senolytics: molecules that selectively eliminate senescent cells while sparing healthy, non-senescent populations. Senolytic agents exploit a specific vulnerability in senescent cells. Because senescent cells produce cytotoxic, pro-inflammatory SASP factors that would normally induce their own death, they become dependent on upregulated Senescent Cell Anti-Apoptotic Pathways (SCAPs) to survive. The SCAP network involves anti-apoptotic proteins (such as BCL-2 and BCL-xL), the PI3K/Akt kinase cascade, and cyclin-dependent kinase inhibitors.Quercetin is a polyphenolic flavonoid found in capers, red onions, apples, and the flower buds of Sophora japonica. Beyond its classical antioxidant properties, quercetin functions as a senolytic compound that exerts multi-target inhibitory effects across the SCAP network. By inhibiting the upstream PI3K/Akt survival axis and downregulating anti-apoptotic defenses, quercetin disrupts the signaling that protects senescent cells from intrinsic apoptosis. Deprived of these survival signals, senescent cells undergo programmed cell death. Preclinical studies demonstrate that senolytic protocols utilizing quercetin - often combined with the tyrosine kinase inhibitor dasatinib - reduce senescent cell burden across multiple tissues. This targeted clearance lowers circulating SASP factors, attenuates tissue fibrosis, restores endothelial reactivity, and improves functional health span. By removing senescent cells, quercetin mitigates the primary driver of chronic, low-grade inflammaging. Modulating the mTOR Pathway for Optimal AutophagyThe mechanistic Target of Rapamycin (mTOR) is an evolutionarily conserved serine/threonine protein kinase that coordinates cellular metabolism by balancing anabolic growth with catabolic recycling. Operating within two multiprotein complexes - mTORC1 and mTORC2 - the mTOR pathway integrates signals from amino acids, growth factors, and intracellular energy levels. In nutrient-rich environments, mTORC1 promotes protein synthesis, lipogenesis, and cellular growth, while suppressing catabolic breakdown. Conversely, nutrient scarcity downregulates mTORC1, activating autophagy.Autophagy is an intracellular degradation system that packages damaged organelles, misfolded protein aggregates, and biological debris into double-membraned autophagosomes for lysosomal degradation and recycling. A specialized branch of this pathway, mitophagy, selectively targets and clears damaged mitochondria. In modern metabolic conditions characterized by continuous caloric intake, mTORC1 can remain persistently active. This persistent signaling suppresses autophagy, causing damaged organelles and toxic aggregates to accumulate within tissues. Quercetin functions as a natural modulator of mTOR signaling. By inhibiting upstream PI3K/Akt signaling and activating intracellular energy sensors, quercetin attenuates overactive mTORC1, mimicking the metabolic effects of caloric restriction. This down-regulation relieves inhibition on the ULK1 autophagy initiation complex, stimulating both general autophagy and mitophagy. As autophagy proceeds, cells clear protein aggregates and eliminate damaged mitochondria, supporting cellular longevity and proteostasis. Enhancing Absorption: Phytosomes and Dietary FatsDespite the biological activities of quercetin identified in experimental models, its clinical translation has historically been limited by poor oral bioavailability. Raw quercetin aglycone is a crystalline, hydrophobic polyphenol with poor solubility in water and gastrointestinal fluids. When ingested in unformulated powder forms, quercetin molecules aggregate in the gut lumen, resisting dissolution and passive absorption. Consequently, the vast majority of an unformulated dose passes into the colon unabsorbed, where it undergoes microbial degradation without reaching meaningful systemic concentrations.To address these pharmacokinetic limitations, advanced delivery systems such as phytosomes were engineered. A phytosome is a 100% food-grade molecular complex where individual polyphenolic molecules are bound to dietary phospholipids, typically sunflower-derived phosphatidylcholine. Unlike a classical liposome - which encapsulates water-soluble compounds inside an aqueous core enclosed by a lipid bilayer - a phytosome forms an amphiphilic complex at the molecular level. The polar head of the phosphatidylcholine molecule forms hydrogen bonds with the hydroxyl groups of the quercetin molecule, while its lipophilic fatty acid tails extend outward. This structural arrangement shields the polar regions of the flavonoid, creating a lipid-compatible complex that integrates smoothly into the intestinal mucosa.
The Importance of Methylation in Healthy AgingVitamin B-Complex and Choline as Essential Methyl DonorsMethylation is an essential biochemical process occurring billions of times each second across all human tissues. It involves the transfer of a single-carbon unit - a methyl group consisting of one carbon atom bound to three hydrogen atoms - (CH3) - from a donor molecule to diverse recipients, including DNA, RNA, structural proteins, neurotransmitters, and membrane phospholipids. This transfer of one-carbon units is coordinated by the methionine-homocysteine cycle, which sustains genetic stability, detoxification pathways, and cellular repair.At the center of this pathway sits S-adenosylmethionine (SAM), the universal methyl donor in human biology. When a methyltransferase enzyme transfers a methyl group from SAM to an acceptor molecule, SAM is converted into S-adenosylhomocysteine (SAH). SAH functions as a potent competitive inhibitor of intracellular methyltransferases. To maintain functional methylation, SAH is rapidly hydrolyzed into homocysteine, a sulfur-containing amino acid that must be remethylated or cleared through transsulfuration. Homocysteine clearance proceeds through two distinct remethylation pathways. The primary route operates across most tissues via the enzyme methionine synthase, which requires vitamin B12 in its active methylcobalamin form. Methionine synthase transfers a methyl group from 5-methyltetrahydrofolate (5-MTHF, the active form of folate) to homocysteine, regenerating methionine. The ongoing production of 5-MTHF depends on the enzyme methylenetetrahydrofolate reductase (MTHFR), which utilizes riboflavin (vitamin B2) as a cofactor. Alternatively, excess homocysteine can be routed into the transsulfuration pathway by vitamin B6 (as pyridoxal-5'-phosphate) to synthesize cystathionine, cysteine, and ultimately the antioxidant glutathione. A secondary remethylation pathway, active predominantly in hepatic and renal tissues, bypasses folate entirely. In this route, dietary choline is oxidized to betaine (trimethylglycine or TMG). The enzyme betaine-homocysteine S-methyltransferase (BHMT) then transfers a methyl group from betaine directly to homocysteine, yielding methionine and dimethylglycine. When dietary intake of active B-vitamins or choline is insufficient, or when genetic variations like MTHFR polymorphisms reduce pathway flux, the methylation cycle slows. Homocysteine accumulates in circulation, promoting vascular and neurological inflammation, while SAM reserves decline, restricting cellular methylation capacity. Understanding DNA Methylation and Epigenetic HealthEvery somatic cell in an organism carries an identical genetic code. Cellular differentiation and tissue-specific functions are governed by the epigenome: a regulatory layer of chemical modifications that dictates gene expression without altering underlying DNA sequences. DNA methylation represents the primary and most stable epigenetic modification. In this process, DNA methyltransferase (DNMT) enzymes utilize methyl groups donated by SAM to add a methyl tag to cytosine bases adjacent to guanine residues, forming 5-methylcytosine within CpG dinucleotide sites.Under physiological conditions, DNA methylation maintains genomic stability and coordinates transcription. Methylation of promoter regions condenses chromatin, repressing transposable elements and silencing genes inappropriate for a given cell type. Conversely, hypomethylated promoters maintain an open chromatin state, allowing transcription factors to bind and initiate gene expression. During biological aging, this epigenetic landscape undergoes progressive dysregulation, a phenomenon termed "epigenetic drift". Aging cells experience global hypomethylation alongside focal hypermethylation of specific gene promoters. Global loss of methyl tags destabilizes the genome, activating retrotransposons and pro-inflammatory pathways. Simultaneously, hypermethylation at targeted promoter sites silences critical tumor suppressor genes and DNA repair complexes. This systematic change in DNA methylation patterns is consistent across populations, allowing researchers to develop molecular "epigenetic clocks". Algorithms such as the Horvath clock, PhenoAge, and GrimAge quantify biological age by profiling the methylation status of specific CpG sites across the genome. These clocks assess whether individuals are aging faster or slower than their chronological years. Ensuring a steady supply of methyl donors and preventing unnecessary SAM depletion supports DNMT activity, maintaining epigenetic patterns and genomic stability. How the Methylation Cycle Impacts Energy and Cognitive FocusBeyond long-term epigenetic regulation, the methylation cycle directly modulates immediate biochemical processes that govern daily energy, neurotransmission, and cognitive focus. Compromised methylation capacity frequently manifests as cognitive slowing, executive fatigue, and reduced physical stamina.A major consumer of methyl reserves is the endogenous synthesis of creatine. Approximately 40% of all SAM-derived methyl groups in the human body are utilized by guanidinoacetate N-methyltransferase (GAMT) in the liver to synthesize creatine. Creatine then translocates to the brain and skeletal muscle, where it is phosphorylated into phosphocreatine. Phosphocreatine functions as a rapid energy buffer, donating a high-energy phosphate group to regenerate ADP into ATP in milliseconds during demanding physical or cognitive tasks. When methyl donor availability falls, endogenous creatine synthesis drops, depleting phosphocreatine reserves and increasing susceptibility to neuromuscular and cognitive fatigue. Methylation is equally central to central nervous system architecture. SAM provides methyl groups to convert phosphatidylethanolamine into phosphatidylcholine, the predominant phospholipid comprising neuronal cell membranes and the myelin sheaths that insulate axons. Intact myelin preserves rapid action potential conduction throughout the nervous system. Furthermore, free choline derived from this pathway is the direct precursor to acetylcholine, the neurotransmitter required for attention, working memory, and learning. The methylation cycle also governs monoamine neurotransmitter metabolism. SAM is required for the synthesis of adrenaline (epinephrine) from noradrenaline, while catechol-O-methyltransferase (COMT) relies on SAM to degrade dopamine and norepinephrine within the prefrontal cortex. Sluggish methylation disrupts this balance, contributing to cognitive fatigue, mood variability, and impaired mental performance. Building a Comprehensive Longevity ProtocolSynergizing NR, Quercetin, and Methylated B-VitaminsLongevity supplementation often falters when single molecules are administered in isolation, ignoring interconnected metabolic pathways. Designing an effective cellular longevity protocol requires combining complementary mechanisms that reinforce one another while preventing secondary metabolic deficits. The combination of Nicotinamide Riboside, Quercetin Phytosome, and Methylated B-Vitamins illustrates this multi-target synergy.This synergy is grounded in the direct biochemical intersection between the NAD+ salvage pathway and the methylation cycle. When high-dose NR is supplemented to boost systemic NAD+, sirtuins and PARP enzymes consume the newly synthesized cofactor, generating substantial quantities of free nicotinamide (NAM). This intracellular nicotinamide faces two primary metabolic fates: it can be recycled back into NAD+ through the NAMPT-dependent salvage loop, or it can be cleared via methylation. When the influx of nicotinamide exceeds salvage recycling capacity, the excess is cleared to avoid feedback inhibition of sirtuin enzymes. To accomplish this, the enzyme nicotinamide N-methyltransferase (NNMT) transfers a methyl group from SAM directly onto nicotinamide, forming 1-methylnicotinamide (1-MNA/MNAM), which is subsequently excreted in urine. Prolonged, high-dose precursor administration without nutritional methyl support can elevate NNMT flux, depleting intracellular SAM reserves. As methyl groups are consumed clearing nicotinamide, the cellular SAM-to-SAH ratio falls, which can elevate circulating homocysteine and reduce methyl availability for DNA methylation and neurotransmitter synthesis. Co-administering a fully methylated B-complex alongside choline or betaine addresses this potential bottleneck. Providing active methyl donors (such as 5-MTHF, methylcobalamin, and betaine) maintains the one-carbon donor pool. Even during increased NNMT activity, SAM pools remain stable, protecting DNA methylation fidelity and maintaining homocysteine within safe parameters. Quercetin reinforces this protocol through complementary mechanisms. By clearing senescent cells and reducing SASP-mediated inflammation, quercetin downregulates CD38, the primary enzyme responsible for age-related NAD+ degradation. Suppressing CD38 prevents unnecessary breakdown of newly synthesized NAD+, enhancing the efficiency of NR supplementation. Furthermore, while NR provides the NAD+ necessary to activate SIRT1-driven mitochondrial biogenesis, quercetin concurrently modulates mTORC1 to stimulate autophagy. This coordinated action ensures that newly generated mitochondria operate in an environment cleared of proteotoxic cellular debris. The Crucial Role of Magnesium Glycinate and Zinc in Cellular FunctionLongevity protocols require essential mineral cofactors to function efficiently. Without adequate divalent minerals acting as enzymatic cofactors and structural stabilizers, metabolic longevity pathways cannot operate at full capacity. Among these, magnesium and zinc are required for cellular repair, genomic stability, and energy production.Magnesium serves as an obligatory cofactor in over 300 enzymatic reactions, primarily through its interaction with ATP. In biological systems, ATP exists predominantly as a chelate with a divalent magnesium ion, forming biologically active Mg2+ -ATP. Every enzymatic reaction that synthesizes, transfers, or consumes cellular energy - including the enzymes of the NAD+ salvage pathway (NRK and NMNAT) and DNA polymerases - strictly requires Mg2+ -ATP as its substrate. Magnesium deficiency impairs these phosphorylation reactions, reducing the cellular utilization of NAD+ precursors. Additionally, magnesium is an essential cofactor for the enzymes that activate dietary B-vitamins into their active forms. Supplying magnesium as magnesium glycinate provides high gastrointestinal bioavailability, minimal laxative effect, and yields glycine to support inhibitory neurotransmission and restful sleep. Zinc serves as a vital structural component for more than 3,000 human transcription factors and enzymatic proteins. Its most prominent structural role in longevity occurs within zinc-finger motifs. These are specialized protein conformations stabilized by a zinc ion coordinated to cysteine and histidine residues. The DNA damage sensor PARP-1 utilizes three zinc-finger domains to identify, track, and physically bind to single- and double-strand DNA breaks. Without adequate intracellular zinc, PARP-1 cannot properly assemble or dock onto damaged chromosomes, impairing DNA repair and increasing genomic instability. Zinc is also an obligatory structural component of copper/zinc superoxide dismutase (Cu/Zn-SOD or SOD1), the primary cytosolic antioxidant enzyme that dismutates superoxide radicals into hydrogen peroxide, protecting mitochondrial membranes and nuclear DNA from premature senescence. Integrating Prebiotics (like Acacia and Inulin) for Gut-Derived Longevity MarkersA comprehensive cellular longevity framework must extend beyond somatic tissues to encompass the gut microbiome. The intestinal microbiome functions as a central regulator of systemic inflammatory tone, immune development, and metabolic signaling. Age-associated dysbiosis - characterized by the loss of beneficial commensals and an overgrowth of pathobionts - frequently leads to breakdown of the intestinal barrier.The gut epithelium consists of a single-cell monolayer sealed by tight junction proteins, including zonula occludens-1 (ZO-1), occludin, and claudins. When this physical barrier is disrupted by poor dietary fiber intake or dysbiosis, gut permeability increases. This allows lipopolysaccharide (LPS), a component of the outer membrane of Gram-negative bacteria, to enter the portal and systemic circulation. The resulting "metabolic endotoxemia" activates Toll-like receptor 4 (TLR4) on immune cells, inducing NF-kB and systemic pro-inflammatory cytokine production. This persistent gut-derived inflammation exacerbates the SASP, accelerates tissue senescence, upregulates CD38, and drains systemic NAD+ reserves.
These short-chain fatty acids, particularly butyrate, exert direct protective effects on systemic longevity. Butyrate provides the primary metabolic fuel for colonic epithelial cells, supplying more than 70% of their baseline energy needs and supporting mitochondrial function within colonocytes. Furthermore, SCFAs upregulate the expression of epithelial tight junction proteins (ZO-1, occludin, and claudin-1), restoring intestinal barrier integrity and preventing the translocation of inflammatory LPS into systemic circulation. Systemically absorbed butyrate also functions as an endogenous histone deacetylase (HDAC) inhibitor, suppressing pro-inflammatory gene expression and supporting regulatory T cell (T_reg) development. Reducing metabolic endotoxemia dampens systemic inflammation, protecting vascular function and preventing premature NAD+ depletion. Conclusion: The Integrated Cellular Longevity MatrixCellular longevity is achieved not by addressing isolated biomarkers in isolation, but by systematically supporting interconnected biological pathways. As bioenergetic capacity declines, cellular senescence accelerates, epigenetic patterns degrade, and gut barrier integrity weakens. A comprehensive approach addresses these biological vulnerabilities simultaneously.
Quercetin Phytosome clears senescent cells and modulates mTORC1, stimulating autophagy while dampening the inflammatory SASP cascade that accelerates CD38-mediated NAD+ destruction. Methylated B-vitamins, active folate, and choline replenish SAM reserves, balancing the methyl requirements of NNMT-mediated nicotinamide clearance, preserving epigenetic DNA methylation, and maintaining neurotransmitter production. Magnesium glycinate and zinc provide the structural and catalytic foundation required for ATP utilization, B-vitamin activation, and PARP-1 zinc-finger DNA repair docking. Finally, prebiotic fibers generate short-chain fatty acids like butyrate, reinforcing the intestinal barrier and preventing metabolic endotoxemia from fueling systemic inflammation. By coordinating energy replenishment, cellular waste clearance, epigenetic maintenance, and the suppression of systemic inflammation, this unified approach directly addresses the underlying drivers of cellular aging to support long-term physiological vitality.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6650) Can DMAE Help With Cellular Cleanup?
Date:
May 28, 2026 01:38 PM
Yes, DMAE - and specifically its highly bioavailable pharmaceutical ester counterpart, centrophenoxine (meclofenoxate) - hits cellular cleanup mechanisms. However, the way it interacts with a stalled system in Parkinson's Disease (PD) is fundamentally different from standard macroautophagy upregulators like fasting or mTOR inhibitors. Instead of just forcing the cell to create more cleanup vesicles, DMAE addresses the structural and mechanical "traffic jams" that cause the system to stall in the first place. The Parkinson's Stagnation: An Autophagic Traffic JamIn Parkinson’s pathology, the primary breakdown in cellular quality control occurs within the autophagic-lysosomal pathway. The accumulation of misfolded a-synuclein proteins builds up into toxic aggregates (Lewy bodies). This doesn't just form static waste; it actively paralyzes the cell's transport machinery, halting macroautophagy, chaperone-mediated autophagy (CMA), and mitophagy (the clearing of damaged, radical-producing mitochondria).Here is how a healthy version of this pathway is structured: As shown above, a healthy cell relies on seamless transport where an autophagosome encapsulates debris and fuses with an acidic lysosome to form an autolysosome for enzymatic destruction. In a stalled Parkinson's state, this crucial fusion and trafficking step is paralyzed. How DMAE Alters Cleanup DynamicsDMAE approaches this bottleneck through two precise biochemical mechanisms:1. Re-greasing Vesicle Trafficking TracksTo build an autophagosome and move it to a lysosome, a neuron requires highly fluid lipid membranes.
2. Direct a-Synuclein DisruptionClassically, DMAE is famous in longevity research for dissolving lipofuscin - the cross-linked "wear-and-tear" pigment aggregate that accumulates in aging cells. While lipofuscin is structurally distinct from the amyloid-like sheets of a-synuclein, modern molecular profiling has revealed that DMAE derivatives possess a powerful cross-over effect:
Mechanics of Clearance: DMAE vs. Traditional Autophagy Inducers
Summary: In Parkinson’s disease, cellular cleanup stalls because toxic accumulations of misfolded alpha-synuclein proteins physically paralyze the autophagic-lysosomal pathway, creating a mechanical traffic jam that prevents waste-carrying autophagosomes from fusing with digestive lysosomes. Rather than simply triggering the creation of more cleanup vesicles like standard autophagy inducers do, DMAE and its highly bioavailable derivative, centrophenoxine, address this bottleneck structurally. It serves as a direct biochemical precursor to vital membrane phospholipids like phosphatidylcholine, restoring lipid bilayer fluidity and essentially "re-greasing the tracks" so stalled cellular transport machinery can resume normal trafficking and waste elimination. Beyond restoring membrane dynamics, DMAE compounds actively disrupt protein aggregation by changing the conformation of alpha-synuclein, which prevents individual monomers from stacking into the toxic, insoluble sheets that choke the cell's internal quality control. This action mirrors its well-documented ability to dissolve lipofuscin, the cross-linked "wear-and-tear" aging pigment that accumulates in aging cells. While free-base DMAE struggles to penetrate the central nervous system effectively due to competition with choline transporters, the lipophilic ester centrophenoxine easily crosses the blood-brain barrier, making it the superior vehicle for restoring neural membrane fluidity and clearing out stalled neurodegenerative debris.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6641) Unlocking the Benefits of Green Tea Extract
Date:
August 10, 2023 10:43 AM
With the growing awareness about the health benefits of green tea, it comes as no surprise that it has become a popular health supplement. One potent green tea supplement that has continued to maintain attention is Natures Answer brand Green Tea Extract in an Alcohol-Free Liquid Extract. Packed with powerful antioxidants, this supplement can aid in digestion, weight management, and overall well-being. Powerful Antioxidant Antioxidants are substances that inhibit oxidation, a process that can lead to cellular damage. They act as scavengers, helping shield the body from harmful free radicals, which are unstable molecules that can inflict damage to our cells. This is where green tea, and particularly green tea extract, shines. Rich in antioxidants known as polyphenols, green tea plays a significant role in maintaining the body's overall health. Polyphenols, including flavonoids and catechins, are known for their potent antioxidant effects. The most notable catechin in green tea is Epigallocatechin Gallate (EGCG), widely studied for its powerful impact on health. Green tea's antioxidants help neutralize harmful free radicals, reducing oxidative stress, and subsequently lowering the risk of a host of chronic conditions including heart disease, type 2 diabetes, and even certain cancers. Thus, the antioxidants in green tea aren't just important, they're an integral part of a health-conscious lifestyle. Boost Immune System Green tea boosts immunity through its potent bioactive compounds, primarily polyphenols like catechins. These compounds exhibit powerful antioxidant properties, neutralizing harmful free radicals in the body. Additionally, they help increase the body's production of detoxifying enzymes, further enhancing the immune system's efficiency. Green tea also contains a type of catechin called Epigallocatechin Gallate (EGCG), renowned for its immune-boosting properties. EGCG aids in the production of T-cells, the body's first line of defense against infections. Furthermore, green tea fosters beneficial gut bacteria, which play a crucial role in maintaining a robust immune system. Promotes Weight Loss Green tea extract works to accelerate weight loss primarily through its active ingredients, one of which is caffeine. Although not as much as coffee, green tea does contain sufficient caffeine that can aid in fat burning and improving exercise performance. More importantly, it is loaded with potent antioxidants called catechins. The most important of these is Epigallocatechin gallate (EGCG), a substance that can boost metabolism. Studies suggest that the combination of EGCG and caffeine in green tea extract can assist in weight loss by helping the body burn more calories, even at rest, and breaking down more fat cells. Additionally, green tea extract is known to increase fat oxidation and improve insulin sensitivity, both beneficial for weight control. While the effects on each individual can vary, when combined with a balanced diet and regular exercise, green tea extract can indeed support and accelerate weight loss efforts. Impacts Central Nervous System Green tea extract is known to have profound effects on the central nervous system, primarily due to the presence of caffeine and an amino acid called L-theanine. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter in the brain called Adenosine. This increases the firing of neurons and the concentration of neurotransmitters like dopamine and norepinephrine, leading to improved brain function, mood, vigilance, reaction times, and even memory. On the other hand, L-theanine can cross the blood-brain barrier and has been shown to increase the activity of the inhibitory neurotransmitter GABA, which has anti-anxiety effects. It also increases dopamine and the production of alpha waves in the brain. The unique combination of these two compounds in green tea extract is believed to make it an excellent tool for maintaining and enhancing the central nervous system. Improve Mental Efficiency Green tea improves mental efficiency through several biological mechanisms. Primarily, it contains caffeine and L-theanine, two compounds known to enhance brain function. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter called adenosine, which not only increases the firing of neurons but also amplifies the concentration of other neurotransmitters like dopamine and norepinephrine. This results in improved brain function, vigilance, reaction times, memory recall, and mood. On the other hand, L-theanine is an amino acid that can cross the blood-brain barrier and has psychoactive properties. It promotes relaxation without drowsiness and can work synergistically with caffeine to enhance brain function. Furthermore, L-theanine increases the frequency of alpha waves in the brain, which leads to improved creativity and problem-solving abilities. Moreover, green tea is rich in polyphenols and antioxidants, particularly Epigallocatechin Gallate (EGCG), which has protective effects on neurons, potentially lowering the risk of neurodegenerative disorders like Alzheimer's and Parkinson's disease. Hence, regular consumption of green tea or its extract can significantly improve mental efficiency. Promotes Heart Health Natures Answer Green Tea Extract Alcohol-Free Extract can help you maintain healthy cholesterol levels, reduce high blood pressure, and prevent blood clot formation that can lead to heart diseases. The polyphenol and catechin compounds in green tea extract are known to promote the health of the heart by reducing inflammation and improving blood vessels' function. Green tea maintains healthy cholesterol levels by inhibiting the absorption of cholesterol in the digestive tract and aiding in its excretion. This leads to a reduced level of LDL (bad cholesterol) in the bloodstream, while not affecting the levels of HDL (good cholesterol). Green tea extract can also lower blood pressure. The catechins it contains help to dilate blood vessels, improving their function and allowing blood to flow more easily. This can lead to a significant reduction in blood pressure, especially in cases of hypertension. Furthermore, studies have shown that the antioxidants in green tea can prevent the oxidation of LDL cholesterol, a process that contributes to the formation of plaques in arteries and blood clot formation. By preventing this oxidation, green tea extract can reduce the risk of heart diseases and strokes. Lastly, the anti-inflammatory nature of green tea's antioxidants helps in reducing inflammation in blood vessels, a condition that can contribute to heart disease. By reducing inflammation, blood flow improves, and the risk of heart disease decreases. In this way, green tea actively promotes heart health. In conclusion, Natures Answer Green Tea Extract is an all-in-one supplement that can enhance your overall health and well-being in various ways. The antioxidant, anti-inflammatory, and weight management properties of this supplement can do wonders for your physical, neurological, and mental health. Incorporating Natures Answer green tea (alcohol free) liquid extract into your daily routine can help you unlock the multiple benefits that this tea has to offer. So, go ahead, give it a try, and reap the benefits of this powerful supplement!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6585) The Many Benefits of Grape Seed Extract
Date:
October 25, 2022 11:46 AM
Did you know that grape seeds are actually a potent source of antioxidants? NOW® Grape Seed Extract is a highly concentrated extract with a minimum of 90% polyphenols, including oligomeric proanthocyanidins (OPCs), which are the potent water-soluble free radical scavenging compounds found in grape seeds.* A growing body of research indicates that grape seed OPCs may help to support the health of vascular, bone, kidney, brain and other tissues by supporting a healthy, balanced immune response to oxidative and metabolic stress.* The Antioxidant Power of Grape Seeds* The natural world is full of antioxidants. These nutrients scavenge harmful toxins and byproducts that can damage cells, leading to inflammation. Inflammation is a major contributing factor in numerous degenerative diseases, so it's important to do everything we can to keep it in check. Some of the best sources of antioxidants are fruits and vegetables—grape seeds included. Grape seeds are an especially rich source of antioxidants due to their high concentration of polyphenols. Polyphenols are micronutrients that have been shown to have numerous health benefits.* NOW® Grape Seed Extract is a highly concentrated extract with a minimum of 90% polyphenols, including oligomeric proanthocyanidins (OPCs), which are the potent water-soluble free radical scavenging compounds found in grape seeds.* A growing body of research indicates that grape seed OPCs may help to support the health of vascular, bone, kidney, brain and other tissues by supporting a healthy, balanced immune response to oxidative and metabolic stress.* What does this mean for your health? Preliminary research suggests that grape seed extract may support cardiovascular health, cognitive function, and healthy aging.* So if you're looking for a way to incorporate more antioxidants into your diet, consider giving grape seed extract a try! In Summary: NOW® Grape Seed Extract is a concentrated source of polyphenols—micronutrients shown to have numerous health benefits.* If you're looking for an easy way to incorporate more antioxidants into your diet, consider giving grape seed extract a try! *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. [*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.]
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6520) Gardenia, widely used in TCM, found to prevent cognitive impairmentand neurotoxicity
Date:
May 09, 2019 09:56 AM
Nobody wants to think about losing their memories as they begin to age. Luckily, a Chinese medicinal herb called gardenia has been shown to contain components that can help improve cognitive function. Scientists studied mice that were given daily doses of gardenia, and the research revealed that a component called GJ-4 had the ability to help repair cognitive damage, reduce brain inflammation, and even help expand the body's ability to hold antioxidants which help promote brain function. Key Takeaways:
"In the study, researchers looked at Chinese herbs, which have been used medicinally for thousands of years, as a good source for potential drugs for Alzheimer’s." Read more: https://www.naturalnews.com/2019-03-28-gardenia-found-to-prevent-cognitive-impairment-and-neurotoxicity.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6291) Is this cruciferous vegetable the key to brain regeneration?
Date:
April 24, 2019 03:12 PM
Scientists have been researching ways of achieving brain regeneration for decades, but the article suggests that cruciferous vegetables is a method of regenerating the brain. An MIT scientist discovered that the growth of nervous tissue is aided by phyto-substances, which is a nutrient that can be found in common vegetables, like broccoli. A compound found in broccoli also has more positive effects on the body, as it has anti-inflammatory properties. Broccoli is helpful for elderly patients that suffer from degenerative diseases. Key Takeaways:
"This natural process of brain regeneration is expedited by certain beneficial phyto-nutrients, and hampered by certain toxic elements." Read more: https://www.naturalnews.com/2019-03-09-is-this-cruciferous-vegetable-the-key-to-brain-regeneration.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6177) Reduces homocysteine levels and acts as an Alzheimers bodyguard?
Date:
March 12, 2019 01:50 PM
The prevalence of Alzheimer's is steadily growing, and researchers are growing more and more concerned at the apparent epidemic. Approximately one in six adults will end up experiencing some form of dementia, and this statistic alone is enough to motivate medical experts to find solutions. Some physicians are finding that taking in adequate amounts of omega-3 fatty acids each day can help prevent the stiffening and inflammation of cells that have the potential to lead to a drop in cognitive function related to dementia. Key Takeaways:
"The influence of marine-based omega-3 fats on physical and mental health has been the subject of intense research for decades, and there’s compelling evidence they can help ameliorate a variety of psychiatric illnesses and degenerative brain disorders, including Alzheimer’s." Read more: https://www.healthnutnews.com/reduces-homocysteine-levels-and-acts-as-an-alzheimers-bodyguard/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6073) Omega-3 Deficiency Symptoms + 3 Steps to Overcome Them
Date:
February 28, 2019 08:47 AM
Omega-3s have a wide variety of benefits for your brain and cardiac health, as well as keeping inflammation in check and hormones in balance, so you definitely shouldn’t let yourself become deficient. Omega-3s are an essential fatty acid, meaning the body cannot produce them on its own. A deficiency can cause inflammation, digestive troubles, and pain in muscles and joints, as well as changes in the appearance of skin and hair. Deficiencies can also cause or worsen ADHD symptoms or depression. A lack of omega-3s can even result in poor brain development in children and neurodegenerative symptoms in adults. Key Takeaways:
"“Omega-3s” is another name for omega-3 fatty acids. These fats are found in the human body, as well as in certain foods like oily fish. Essential fatty acids are “essential” because the body cannot synthesize them on its own, therefore humans must get these fats from the diet." Read more: https://draxe.com/omega-3-deficiency/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6060) Zinc can protect against oxidative stress when it's taken togetherwith chocolate and tea
Date:
February 08, 2019 03:48 PM
As human cells burn energy in their processes, they give off "exhaust", if you will(cellular expiration), which can cause damage to components of the cell and surroundings. One of the byproducts in this respiration is superoxide, which may have a role in the aging process and other degenerative problems. However, there may be a metal that may help without hurting: zinc. And, some reseachers say, taking zinc with items such as chocolate or wine may enhance the process zinc has in breaking down the superoxide. Key Takeaways:
"A study published in the journal Nature Chemistry suggests that the nutritional benefits of zinc can be bolstered when combined with a natural compound found in chocolate and tea." Read more: https://www.naturalnews.com/2019-02-04-zinc-protects-against-oxidative-stress-with-chocolate-and-tea.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6011) Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's
Date:
January 04, 2019 08:12 AM
Pyrroloquinoline quinone (PPQ) is a microbe that is derived from plants, and it is showing to have neurological benefits that are associated with the prevention of Alzheimer's progression. This particular microbe is able to reduce inflammation in the brain, which can lead to several neurological conditions. It also helps patients in post-stroke recovery because it is able to reduce the area of the brain that is impacted by stroke activity. Most importantly, it helps in the prevention of Alzheimer's due to how it can neutralize levels of oxidative stress. Key Takeaways:
"Glutamate is an important chemical in the brain, but too much of it results in excitotoxicity, a risk factor in both stroke and neurodegenerative disease. PQQ protects the brain from overstimulation by glutamate and the resulting death of brain cells." Read more: https://www.naturalnews.com/2018-12-15-ppq-can-prevent-alzheimers.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5928) PQQ is effective in combating neurodegeneration that can affect theaging brain
Date:
December 21, 2018 08:53 AM
A nutrient called Pyrroloquinoline quinone (PQQ) has shown potential for combating the degenerative neurological symptoms of Alzheimer’s, according to research published by Life Extension. Mice that were given a PQQ supplement developed smaller deposits of toxic proteins in their brains compared to the mice that did not, and also demonstrated better recall, memory, motor skills and learning relative to the control group. Other research suggests PQQ may help with Parkinson’s symptoms, and improve blood circulation within the brain. Key Takeaways:
"But there are many ways in which a person can reduce their risk of neurodegeneration as they age, like healthy eating." Read more: https://www.naturalnews.com/2018-12-13-pqq-combats-neurodegeneration-that-can-affect-the-aging-brain.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5916) Why your brain fails as you age, what you can do now
Date:
August 24, 2018 09:53 AM
It is the mitochondria inside your organelles that produce adenosine triphosphate, and if it does not function now then that is bad news for you. It means that your risk of developing a degenerative disease rises dramatically. No organ in your body is more dependent on energy than your brain, and older people who have their energy impaired open themselves up to such diseases. Additionally, as one ages, their mitochondria is decreased in functions and numbers. Key Takeaways:
"If your mitochondria are not functioning well, your risk for chronic degenerative diseases will radically increase." Read more: https://www.healthnutnews.com/why-your-brain-fails-as-you-age-what-you-can-do-now/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5721) Gut microbes play a significant role in the central nervous system digestive health is linked to your risk of neurodegenerative diseases
Date:
August 07, 2018 09:53 AM
Neurodegenerative diseases like Alzheimers are becoming more and more common in the United States, and pose an increasing risk to aging populations. A recent study has identified gut microbes as one of the causes of these diseases - a huge breakthrough in the field, and one with significant implications for how we view our brain's health. These microbes release chemicals that can change the nature of the brain. It's a finding that shows that caring for our digestive health can be one of the most important steps to preventing diseases like Alzheimers, later on. Key Takeaways:
"They reached their conclusions after examining gut microbes and changes in mouse models of multiple sclerosis. They discovered the compounds produced by the breakdown of tryptophan cross the blood-brain barrier and activate an inflammatory pathway that can limit neurodegeneration." Read more: https://www.naturalnews.com/2018-07-30-gut-microbes-play-a-significant-role-in-the-central-nervous-system.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5695) Avocados are one of the simplest and most satisfying ways to prevent degenerative disease
Date:
August 06, 2018 09:53 AM
Avocados are an incredibly nutritious food rich in fiber, potassium, a plethora of vitamins and healthy fats like oleic acid. Avocados have a lot of uses in protecting against degenerative diseases. For example, the healthy fats in avocados can lower cholesterol. Avocado also contains compounds that can help to control blood sugar, protect your joints from arthritis and reduce the impact of oxidative stress on your liver. Avocados are also tasty and satiating, which can be useful qualities for helping people stick to diets and keep their weight under control. Key Takeaways:
"Without a doubt, the avocado is a fruit that needs to be part of everyone’s diet." Read more: https://www.naturalnews.com/2018-08-02-avocados-are-one-of-the-simplest-ways-to-prevent-degenerative-disease.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5693) Bitter melon extract found to help treat diabetes with its anti-obesity effects
Date:
July 26, 2018 09:09 AM
Bitter melon may be an unusual thing to incorporate into your diet. But, you may want to look into some recipes. It turns out that there is a wealth of study data that shows that bitter melon is a potent health ally, particularly when it comes to individuals who are fighting a losing battle with weight and some of the chronic conditions that go with it. There's scientific proof attesting to the fact that bitter melon aids the body in balancing its metabolism with lipid intake. It also benefits a syndrome marked by high levels if glucose in the blood and weight gain around the middle. It also tends to dampen the body's accumulation of adipose tissue. So, while it may not be a taste treat, it may be beneficial, nonetheless, to put some bitter melon on your plate. Key Takeaways:
"Bitter melons may taste unpleasant to some people, but its health benefits cannot be denied." Read more: https://www.naturalnews.com/2018-06-13-bitter-melon-extract-found-to-help-treat-diabetes-with-its-anti-obesity-effects.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5679) Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)
Date:
July 04, 2018 05:54 PM
A recent Kristina University study suggests that fermented turmeric may help protect brain cells from being degraded by inflammation and oxidative stress. The same researchers found that fermented turmeric may also help protect against the impact of the amnesiac compound scopolamine. Researchers subjected scopolamine-treated mice to mazes and inflicted oxidative stress on rat brain cells to test whether fermented turmeric offered any protection. Preliminary results suggest that fermented turmeric could have value as an alternative or complementary treatment for neurodegenerative diseases symptoms. Key Takeaways:
"It could serve as an alternative or complementary therapy for age-induced neurodegenerative diseases like Alzheimer’s disease." Read more: https://www.naturalnews.com/2018-07-02-scientists-study-neuroprotective-effects-of-fermented-curcuma-longa-turmeric.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5655) Boysenberries found to improve cholesterol, help prevent heart disease
Date:
July 01, 2018 05:54 PM
Researchers from Japan have discovered that eating boysenberries can help in the prevention of heart disease and even lower one's cholesterol. In fact, boysenberries contain even more polyphenols than raspberries do. These nutrients help stave off degenerative conditions, such as heart disease. They also supply consumers with a healthy amount of antioxidants and that reduces several chronic conditions, like atherosclerosis. In addition, boysenberries help with the reduction of cholesterol excretion, especially in a person's small intestine. Key Takeaways:
"Eating delicious boysenberries can improve cholesterol and prevent heart disease, reported a Japanese study." Read more: https://www.naturalnews.com/2018-06-28-boysenberries-found-to-improve-cholesterol-help-prevent-heart-disease.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5653) 4 Natural Ways To Remove Age Spots - How To Remove Aging Signs And Dark Spots
Date:
October 04, 2017 12:14 PM
There are 4 natural ways to remove aging signs from your skin. You can also get rid of dark spots that are on your skin. Our face and hands are affected the most. Our eating habits as well as our skin care routines are both very important things. They are important because they prevent and reduce aging spots on our skin. Age spots are a common sign of aging and they could appear around 40 years. https://www.youtube.com/watch?v=c5gF-zAHRds&rel=0Key Takeaways:
"Spending a couple of hours outside is important for our bodies to generate vitamin D. However, spending too much time, especially during the summer, damages the top layers of our skin and accelerates the degenerative process."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5309) Foundations in Health
Date:
August 04, 2017 09:14 AM
The key to a house that will last for a long time is a strong foundation. The same goes for your health. In nutritional therapy, there are five pillars of foundational health. When these pillars are very weak, opportunities for many different degenerative conditions are introduced. Through this lens, taking charge of your overall health becomes a lot more accessible. If you ignore the foundation, that will lead to relying on pharmaceuticals or other conventional therapies. Key Takeaways:
"The five pillars of foundational health are digestion, blood sugar balance, mineral balance, fatty acid balance and hydration. Holding these essential components together is a whole foods diet." Read more: https://www.echoak.com/2017/08/foundations-in-health/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5083) Advantages And Disadvantages Of CBD Oil
Date:
July 25, 2017 12:14 PM
There are some advantages and disadvantages of CBD oil. CBD oil is a derivative of cannabis. The origin of this oil is the marijuana plant. It does not intoxicate anyone that uses it. There have been several controversies that have emerged because its parent plant is used for recreational use. But, there are many indications of the health benefits it offers. Marijuana consists of some quantity of CBD. One of the benefits of CBD oil is decreased anxiety. Key Takeaways:
"CBD oil can help in managing anxiety attacks by changing the response produced by brain receptors towards serotonin." Read more: http://reportshealthcare.com/advantages-disadvantages-cbd-oil/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5033) CBD and Your Brain
Date:
June 14, 2017 12:14 PM
CBD is found in cannabis sativa otherwise known as marijuana and is useful in treating many neurological disorders such as depression, anxiety and even epilepsy. Unlike THC, CBD has no psychoactive effects. CBD has been found to protect brain cells from harm in neurodegenerative diseases like Alzheimer's. Best of all CBD has literally zero side effects! Research shows that CBD has opened many doors leading to a cure for depression and anxiety. CBD has been proven to reduce swelling, pain and inflammation caused by injury and arthritis even when applied topically. CBD may not be a medical cure all but it has been proven to be a very useful tool in the treatment of many medical conditions. Key Takeaways:
"When various brain injuries from animal models were examined, it was found out that CBD boosted a number of viable brain cells." Read more: https://www.cashinbis.com/cbd-and-your-brain/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4831) Eat This One Food To Get Rid Of Brain Fog
Date:
March 18, 2017 06:44 AM
Omega-3 fatty acids play an important role in our health including anti-inflammation, reducing the risk of chronic diseases, maintaining brain function. ALA, DHA and EPA are 3 types of omega-3s that are most beneficial to our brain such as effects on depressive conditions, post-stroke, neuropathic pain, migraines, neurodegenerative disease and improving cognitive performance. ALA comes from plants. DHA and EPA are found in fatty, cold-water fish and shellfish. A balance of sources from plants and seafood will help you to find the right balance of these essential fatty acids, which is fundamental to prevent inflammation. Make sure to consult with your healthcare provider to find out the amount that is best for your unique condition. Key Takeaways:
"A well-balanced diet with natural sources of ALA, DHA, and EPA is fundamental to maintaining a healthy ratio that prevents inflammation and promotes long-term health." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4199) Cannabidiol (CBD) Inhibits Cancer Growth According to Medical Researchers, Announces Phillip Fry
Date:
March 12, 2017 04:59 AM
More and more, the non-psychoactive marijuana extract called Cannabidiol or CBD is becoming an alternative treatment. Research has existed that pointed to CBD's uses for treating nausea in chemotherapy patients, fighting neurodegenerative diseases and seizures in patients, but the most recent findings could indicate that CBD is more useful than ever imagined. Recent studies have concluded that CBD, which is an extract that doesn't have the psychoactive aspects marijuana is known for, shows significant signs of fighting cancers cells for a number of different types of cancer. The scientific community is publishing a record number of research, much of it pointing to the marijuana extract, CBD, having unknown but possibly lifesaving potential. Key Takeaways:
"Chemical components of Cannabis, called cannabinoids, activate specific receptors throughout the body to produce pharmaacologic effects" Read more: http://www.digitaljournal.com/pr/3259779
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4111) Researchers identify how inflammation spreads through the brain after injury
Date:
March 09, 2017 02:59 PM
Researchers have identified a new mechanism by which inflammation can spread throughout the brain after injury. This mechanism may explain the widespread and long-lasting inflammation that occurs after traumatic brain injury, and may play a role in other neurodegenerative diseases. This new understanding has the potential to transform how brain inflammation is understood, and, ultimately, how it is treated. Key Takeaways:
"This new understanding has the potential to transform how brain inflammation is understood, and, ultimately, how it is treated." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4097) Mushrooms 'can reduce dementia' by boosting nerves in the brain
Date:
January 31, 2017 10:59 AM
Dementia is a serious issue for the elderly. There isn't too much known about it. Here one option for possibly lessening the chances of it is mentioned. Mushrooms can help. They help the nerves in the brain. It's definitely work a look, especially if dementia runs in your family or if you are just concerned about it in general. Key Takeaways:
"Current drug therapy for neuro-degenerative diseases is ineffective with many side effects - and it only provides a short-term delay in progression." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3856) Running may boost your brain wiring
Date:
December 21, 2016 07:59 AM
If you want to boost your brain function, try running. A study conducted at the University of Arizona found that brain scans of runners showed greater cognitive function that in those of people who do not regularly exercise. The areas that were more active in runners were also identified as the areas that deteriorate with older age, so there is the question as to whether or not physical activity will help stave off Alzheimer’s and other cognitive issues later in life. Key Takeaways:
"Make running your New Year’s resolution if you want to boost your brain function, say scientists who have found that cross country runners have greater connectivity in brain areas linked to planning and decision-making." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3680) Fruits and vegetables may slow ALS
Date:
November 16, 2016 01:04 PM
We know we should eat more fruits and vegetables, but it turns out that a diet high in these too foods may also help with diseases like ALS. Studies are showing that the foods we eat play a huge rule in both triggering and the prognosis of the disease. Lunch meats and milk should be avoided, while foods high in fiber and some meats may actually help. Key Takeaways:
"New research at Columbia University's Mailman School of Public Health reveals that foods like fruits and vegetables that are high in antioxidant nutrients and carotenoids are associated with better function in amyotrophic lateral sclerosis (ALS) patients around the time of diagnosis." Reference: https://www.sciencedaily.com/releases/2016/11/161101102618.htm
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3454) Top 10 amazing, indigenous, all-natural cures from around the world
Date:
November 05, 2016 10:54 AM
When it comes to medicine what you put in to your body is important. For centuries people used natural cures from around the world to cure what ails them. Today we are quick to look to traditional medicine but perhaps it is time we step off the beaten path. Key Takeaways:
"Try the top 10 amazing, indigenous, all-natural cures from around the world, and never suffer another side effect, never perpetuate illness, and never, ever eat cancer again." Reference: //www.naturalnews.com/055836_natural_cures_indigenous_medicine_healing_plants.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3391) Bulletproof coffee - coconut and butter does improve health
Date:
September 23, 2016 02:44 PM
A cup of coffee is a common thing that most of people drink in the morning. However, since many people realized that coconut oil and butter are healthy fats (Axe, 2016), they started replacing cream with them. This coconut and/or butter coffee is known as bulletproof coffee and it is a new trend of healthy morning drink. It has been extremely popular all over the world.
Coconut oil has so many benefits for your body, such as:
· Increases your energy - its ingredient, MCT (Medium Chain Triglycerides), is absorbed by the body and metabolized as fuel more quickly (Tifanny, 2016).
· Improves your immune system - There is a lot of lauric acid in coconut oil that is effective to prevent and cure many viruses (WebMD in Tifanny, 2016).
· Improves brain function – Its fatty acid plays an important role in memory and brain functions (Axe, 2016).
· Promotes heart health – Coconut oil contains good cholesterol that is good for your heart (Axe, 2016).
· Acts as anti-inflammatory – Antioxidant content makes coconut an effective anti-inflammatory food that help reduce arthritis (Axe, 2016).
· Is good for hair and skin – It is able to smoothen and tighten the skin, as well as maintain healthy hair (Axe, 2016).
On the other hand, butter also offers many advantages for your health, such as:
· Prevents and treats many diseases - Omega 3 fatty acids in butter are essential for growth, as well as prevention and treatment of arthritis, coronary artery disease, cancer, inflammation, and high blood pressure (Leonard, 2016).
· Improves your brain, blood circulation, and hormonal system – It helps prevent neurodegenerative and heart diseases, increase energy expenditure, and act as anti-inflammatory (NN, 2014).
· Is good for bones and blood circulation – Butter contains vitamin K that plays an important role in blood clotting and keeping the bones strong (Leonard, 2016).
· Helps with weight loss – It makes you feel full for a longer period and its conjugated linoleic acid (CLA) is an effective aid for losing weight (Leonard, 2016).
· Reduces caffeine sensitivity – Butter fat can protect the stomach from shakes and nausea caused by caffeine (Leonard, 2016).
· Boosts the energy – It provides more sustained energy for the body (Leonard, 2016).
· Accelerates metabolism and digestion – Vitamin A, D, and E contained in butter are easily absorbed by the body and stored in gastrointestinal tract (Axe, 2016).
Based on the facts above, coconut and butter coffee is a healthy drink. However, excessive consumption of this bulletproof coffee is not good. Healthy fats can only function effectively in the body if the amounts taken are mooderate, not more and not less. Moreover, drink this coffee as the replacement of your breakfast is not recommended since it does not have enough essential nutrients (Gunnars, 2016).
References
https://authoritynutrition.com/3-reasons-why-bulletproof-coffee-is-a-bad-idea/
https://draxe.com/healthy-fats/
//nextshark.com/neil-degrasse-tyson-reveals-just-how-broke-you-are-compared-to-bill-gates/
//thecoconutmama.com/coconut-oil-coffee/
//www.naturallivingideas.com/add-butter-to-coffee/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3311) Inflammation Pain Got You Down? EPA Fish Oil Can Help
Date:
October 12, 2015 12:55 AM
There's absolutely no doubt as to whether fish oil contains anti-inflammatory benefits. The main question is how one can tap into these benefits. How fish oil helps in inflammation pain is well understood. Basically, fish oil contains EPA and DHA which are Omega 3 fatty acids. Our body cannot make these essential fats on its own, and it's therefore important to have them in included in the diet just like other minerals and vitamins. Effects of Inflammation Pain Fish oil has shown to have potential benefits to all these diseases, but the main question is how one substance could help so many different conditions. However, fish oil contains essential omega 3 fats that benefit a wide variety of health conditions, either related or caused by inflammation. How EPA helps inflammation EPA (Eicosapentaenoic acid) is an omega 3 fatty acid present in fish oil and is used by the body as a building block for manufacturing a group of chemicals with anti-inflammatory effects. This simply means that EPA acts as the fuel for the ability of our body to make its own anti-inflammatory chemicals. Scientists and nutritionists have shown that our modern diet is deficient in these omega 3 fatty acids. They also suggest that this may serve as an explanation of the current epidemic of inflammatory pain related illnesses that are being experienced in most western countries. EPA fish oil dosage In order to achieve significant anti-inflammatory effects, you must take a large daily dose of EPA-rich fish oils. One study has shown that patients suffering from disabling pain are able to achieve a significant pain relief that could not be helped by prescriptive pain medications, after taking high doses of fish oil for a prolonged period of time. In this study, all the patients had suffered severe disabling pain that could not be relieved through prescriptive pain medications. The pain was caused by something different in each of the cases. One of the patients had second and third-degree burns over large parts of his body and was still experiencing pain despite taking morphine. Another patient had suffered a disc herniation in his neck. In all these cases, patients experienced significant relief after taking high doses of EPA fish oils and were able to return to their normal daily living. The fish oil daily dosage included 3200 mg to 7000 mg of EPA and DHA combined. Assessing your need for omega 3 The expected results from taking fish oil largely depend on your current intake of omega 3 fats. If your body is currently depleted on omega 3 fats, it will certainly take much longer before it reaches the optimal levels of omega 3 and to achieve the full benefits of EPA. To determine your current omega 3 status, a simple blood test can measure your Omega-Index. Resources: //www.webmd.com/diet/what-to-know-about-omega-3s-and-fish
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3227) Wheatgrass - A Superfood To Improve Your Energy Levels
Date:
August 15, 2015 01:52 AM
The most nutritious of all cereal grasses is wheatgrass. It is richest in nutrients when it is grown in clean soil and just before the development of its stem. The most interesting factor is that it does not contain gluten. This article aims to list some of the health benefits of wheatgrass and how it can boost energy levels.) Wheatgrass contains over 90 minerals including Mg, Ca, Na, etc. It has a rich concentration of alkaline minerals. It contains a number of enzymes such as Lipase (splits fat), Amylase (helps in digestion), Protease (helps to digest protein), and Transhydrogenase (strengthens the heart muscle,etc. , among others). Wheatgrass contains high doses of vitamin C, almost twice the amount of Vitamin A as in carrots and a full complement of B vitamins. A teaspoon of wheatgrass powder is nutritionally equivalent to 50 g of spinach salad and supplies an equivalent amount of energy. Wheatgrass contains 19 amino acids.
Benefits of Taking Wheatgrass Containing a high number of enzymes vitamins and minerals, it boosts vitality and energy levels. It enhances detoxification and aids in maintaining the correct acid-alkaline base in the body. The high vitamin content helps to increase endurance and stamina levels in the body. Chlorophyll contained in the wheatgrass works to increase production of hemoglobin in the body. With increased blood circulation, the body’s metabolism is improved with increased energy levels. Chlorophyll also serves to alkalize the blood. This slows down aging, increases energy levels, and slow down/prevent degenerative diseases such as arthritis and gout. The B vitamins and iron in wheatgrass reduce tiredness and fatigue and give way for a more energy in their place. The quick and easy absorption of wheatgrass also contributes to effective assimilation of the nutrients that it contains in the body.
Wrapping up, wheatgrass is one of nature’s most nourishing superfoods that you can lay your hands on.
References https://www.nutrifiz.co.uk/10-benefits-wheatgrass-drinks-revealed/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3194) What Are Glycosaminoglycans (GAGs) And What Herbs Contain Them?
Date:
July 21, 2015 08:53 PM
Glycosaminoglycans refers to a linear unbranched polysacharide chain molecule composed of disaccharides repeats with a high negative charge due to the presence of Uronic acid components and sulfate esters with some hydoxyl (OH) groups as part of its structural components. They have varying molecular size and sulfation depending on the tissue they are located on and their state. They function to attract cations and maintain the hydration of the extracellular membrane (E.C.M). Glycoaminoglycans are classified into different groups based on different categories which include; glycosidic linkages in their structure, type of the sugar moiety, sulphate groups numbers and the location of the sulfate groups. Based on this various classification categories six major groups of GAGs exists, namely; heparin, hyaluronan, dermatan sulfate, heparin sulfate, chondroitin sulfate, and keratan sulfate. GAGs have a high solvation degree and and are as well highly viscous. This is beneficial to the body in that it helps to cushion and lubricate various connective tissues and body joints respectively. It therefore protects an individual from joint pains due to poor lubrication of the joints causing the bone to slide over each other. They also form the building blocks of proteoglycans which are the major building blocks of the extracellular matrix. Due to this property they are vital in determining the cellular activities such as cell division because the cell division machinery has to attach itself to the extracellular matrix before the division process is initiated. Some body tissues such as the nerve cells and the muscle cells require continuous cell division to replace worn out cells for the normal functioning. This means that structural deformities in the extracellular matrix will hinder the division process to occur and is most likely to lead to some neurodegenerative complexions. Recent studies have linked GAGs to play a role in the cell biology of cancer.They have been established as the key macromolecules affecting cell properties and functions through interaction with key growth factors or by acting directly as receptor molecules. Through this it has been findings they play a vital role in the cell signaling process thus playing a role in the cancer disease progression.Heparin and heparin sulfate have been indicated through studies to have anti-tumor effects by preventing the process of angiogenesis which is the first step in cancer metastasis.Some have been associated with anti-coagulant properties.
Therefore GAGs are important molecules which play a vital role in protection against various forms of cancers. GAGs aremostly obtained from animal sources. The animal sources include shark fish and ray skeletons. Plants are also sources of GAGs, however their digestion by the human system is not possible. Seaweed is one herb that is rich in GAGs. However as earlier explain the digestion of the sea weed by the animal digestive system is quite a challenge. It is therefore recommended that we eat foods rich in proteins, and carbohydrates which can be used to synthesize GAGs in the body. In summary, GAGs are heteropolymers which acts as the building blocks of the extracellular matrix in animals. The body has the ability to synthesize GAGs naturally hence nutritional supplement is required for the body to obtain key components necessary for the synthesis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3178) Dental Benefits of Xylitol; Protect your teeth against decay.
Date:
October 07, 2014 08:34 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3161) Importace of vitamin k-2
Date:
June 06, 2014 04:08 AM
We all know that calcium is needed for healthy bones and teeth. If calcium deficiency in the body is neglected for many years, it may cause bone disease in old age, which is also known as osteoporosis in medical terms, and many other complications. Vitamin K-2 works to help with the absorption of the calcium ions in the body. Calcium supplements Calcium supplements or tablets are normally recommended by doctors all over the world to overcome calcium deficiency. There are tablets that one can use to replenish the calcium in their body. Therefore, calcium supplements and one's bone health are closely related to each other. By taking vitamin K-2, there will be no need of taking the supplements. Where can you find calcium Calcium is mostly found in our bones, teeth, blood and cells. Almost 98% of calcium present in the body is concentrated in the bones where it is needed for the right development of the skeletal system. It has also a lot of vitamin K 2 which will help in absorption of the calcium important in the formation of bones. Calcium supplements and one's bone health are connected by the very fact that they will not only help in overcoming calcium deficiency in the body, they will also help in preventing many degenerative diseases that are related to the skeletal system for instance osteoporosis. Our immune system is the one that is responsible for maintaining the health of our bones. However, as we age our immune systems becomes weak and do not perform at its maximum due to other health conditions. At this age, doctors nowadays advocating for nutritional supplements for bone health and health specialists. Liquid calcium supplements together with the tablet forms offer many benefits in respect to the overall well being of your body. The vitamin K-2 will help in keeping the immune system strong, giving us strong bones. Source:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3132) What Are The Health Benefits Of PABA
Date:
May 10, 2014 04:30 AM
Para-amino benzoic acid or PABA is generally not known, yet in any case it is a paramount supplement, however it is considered as one of the B-complex vitamins. The perplexity is maybe justifiable because PABA assumes a paramount part in the production in the collection of a standout amongst the most essential B-complex vitamins and folic acid. Benefits of folic acid The numerous vital benefits of folic acid have been generally recorded, the most critical likely being the avoidance of genuine conception deformities, especially spina bifida; and additionally insurance against stroke, cardiovascular malady and even certain malignancies. In reality, sufficient supplies of folic acid are viewed as so significant to wellbeing that staple sustenance, for example, bread are routinely enhanced with it. In any case the regular Western eating regimen is accepted by numerous nutritionists to be seriously insufficient. PABA's part in empowering the union of the body's vitamin might subsequently be viewed as sufficient in itself to make it a vital supplement in its own particular right. Nevertheless there is much more to para-aminobenzoic acid than this. The supplement has additionally been considered a general agains oxidant, help check the maturing and degenerative impacts of harming free radical action; and as a mitigating which may be gainful in the lightening of the indications of the menopause and osteoarthritis. The calming properties of PABA likewise make it a specific most loved by dietary specialists in battling glitches of the resistant framework, for example, thyroiditis, and a possibly deadly condition known as scleroderma, in which stringy tissue develops through the skin. Moderate supplements of PABA were an old yet now unfashionable, medication for skin conditions, vitiligo, in which the skin loses its common pigmentation, bringing about unattractive and humiliating blotches. For most individuals, in any case, the great thing about PABA is that, it is not just promptly accessible from the nourishments, which embody a steadily adjusted eating regimen, yet can additionally be made by the body. Therefore, in customary circumstances, and in case you're in sensibly great wellbeing, you presumably need not bother with a different day by day supplement of PABA. Anyhow like all the B complex vitamins, PABA regardless capacities best in the vicinity of a great supply of every last one of others, thus it’s habitually found in restrictive multi-vitamin arrangements. The better quality ones usually incorporate around 30-50mg; a little add up to make it certain, however worth having as a protection strategy when you're pointing for ideal comprehensive nourishment, and especially when you acknowledge the supplement's pivotal part in the combination of folic acid.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3116) VITAMIN - D3:A reservoiur of benefits to sheenful life
Date:
January 03, 2014 05:29 PM
Vitamin D3 Sources
Apart from the tablets or liquid vitamin D-3 supplements, fortified milk, breads, cereals and eggs are lesser vitamin D3 sources. Lists of health benefits for Vitamin D-3:
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2950) What Is GABA And Why Is It Important For The Brain
Date:
December 21, 2013 01:22 AM
The human brains need various supplements to make it work better. One such supplement is the gamma aminobutyric acid, abbreviated as GABA. It is the second most important neurotransmitter for the brain. The neurotransmitters allow synapses that transfer information to gray matter in human. This amino acid gives human an inhibiting experience thus making one calm. This makes it possible for one to have a feeling of well being and tranquility. GABA on Human Body GABA is useful in the human body because it acts as neurotransmitters. This means you are protected from nerve impulses. This neurotransmitter cools the brain. Research has shown that it helps to increase alpha wave production. This is related to the feeling of relaxation we have in brains. With enough GABA, it is known to prevent the feeling of insomnia. This comes when neurons firing decreases to make one have a restful sleep. The calming effect helps an individual’s brain to have elevated moods which is an important part for reducing blood pressure. To enable an individual have more concentrations when working, they need to have increased levels of GABA. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2933) Coconut Oil for Memory Enhancement
Date:
December 27, 2012 12:53 PM
Coconut oil has been widely used for centuries for various purposes. Mainly, it is a cooking ingredient, used for frying and for adding flavor to meals. Aside from this, many nations have different ways of using it as treatment for various illnesses. Countries like Jamaica, Panama, and India believe that ingesting the oil helps prevent contracting any disease and helps in the speedy recovery when sick. Topical Uses: People from the Philippines and Thailand use the oil for massaging to provide relief from painful muscles and joints. Other topical uses are for moisturizing of the skin and for the healthy growth of hair. Since 2008, new studies have been conducted to test the effects of coconut oil in enhancing the memory and to cure Alzheimer's disease. MCT (Medium Chain Triglycerides) Benefit: The most astounding find is the presence of MCT or medium chain triglycerides in coconut oil in high concentration. This MCT creates a string of processes that ultimately helps in curing neurodegenerative diseases. MCT against Amyloid-Beta
Amyloid-beta is a protein that forms into plaques in the brains. They decrease the efficient functioning of the nerve cells that then causes the decline in memory. Most drugs prescribed to Alzheimer patients target these plaques, to dissolve them and consequently see an improvement. Studies done on dogs by incorporating MCT in their diets showed that the levels of amyloid-beta has declined, which is a very positive effect. Likewise, energy levels in the brain have gone up among the test subjects. MCT to Promote Ketone One cause of Alzheimer's disease is the inability of the brain to metabolize glucose and transform it to energy. As you all know, glucose is the main energy source of the body that provides it the energy it needs to function. This glucose comes from the carbohydrate that comes from food sources. Without this fuel, the brain cells could degenerate. Fortunately, glucose is not the only source of energy for the brain. It can also come from ketones, which are produced from fats in the liver. However, the liver does not continually produce this. The human body, being smart as it is, only produces ketones when the glucose level drops in order to compensate for the loss of energy source. This is why people who have cognitive disorders often go on a fat and protein diet to trigger the production of ketones, by lowering their intake of carbohydrates. Still, maintaining such a diet for long periods is hard. The good thing is studies have shown that ingesting MCT has increased the level of ketones in the body, regardless of the amount of glucose present in the system. It is believed that MCT is converted to ketone, thus, providing the brain the energy it needs. MCT and Omega-3 Fatty Acids Another study done on dogs showed an increased level of omega-3 fatty acids in their brain. Omega-3 fatty acids have many benefits to the body, including improvement of brain function. They support the effective transmission of energy from one neuron to another through the synapses. This consequently makes learning easier, promotes faster reactions, and heightens memory. Unfortunately, this fatty acid is not produced in the body and people have to rely on food sources, such as fish and nuts. Studies have shown that MCT from coconut oil induces the production of omega-3 from fats that are already present in the body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2781) Coq10 and its benefits
Date:
October 26, 2012 11:04 AM
CoQ10 We insist that vitamins and essential nutrients should be an essential part of our daily diet. But are we aware that some vitamins and chemical nutrients are also created naturally in our bodies? One such essential compound is known as Coq10. Found in most living organisms, Coq10 also known, as ubiquinone is a chemical that boosts the levels of energy produced in the body. It monitors the functioning of the mitochondria and cells that are useful for metabolizing the fat in the body. Without the presence of this essential compound, there could be some serious problems. Here are its respective virtues for people. Heart And Muscle Repair Scientific studies have proved that the enhanced production ofCoq10 has helped to solve some major health issues for people. The enhanced production of the compound was instrumental in strengthening the muscles and tissues of the heart. This meant that adequate levels of Coq10 help to reduce the congestion in the heart and veins. Also, the presence of this ubiquitous compound will also help in getting respite from muscular dystrophy. Also, those, who are vulnerable to breathing problems and arrhythmia, can also find a solution through such a compound in their bodies. Immunity And Blood Pressure Those, who have the problem of high blood pressure, would be advised to eat more of things like fish or meat as these contain Coq10 in good amounts. Adequate levels of this chemical will aid in reducing the levels of blood pressure and improving the circulation of blood in the body. Also, Coq10 is known for improving the person's immunity against the common degenerative diseases as well as cancers and malignant tumors and so on. Thus, it can be safely said that Coq10 is a powerhouse of nutrients that help to keep disastrous afflictions at bay. You should have more of it.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2694) What Are Benefits of Goji Berries
Date:
August 12, 2012 11:54 PM
Goji Berry Found extensively in Asia and southeastern Europe, the wolfberry, also known as the Goji berry, is one of the most important medicinal plants. It belongs to the same fraternity as pepper, tomatoes, potatoes and other such similar plants. The Goji Berry is mainly found in the wilderness of the Himalayas as well as the snowy expanses of Tibet. The plant has a number of health benefits and virtues. Here is a look at them. 1-Vitamins and Proteins Among the different medicinal plants, Goji berries are rare because they have a lot of proteins. The plant is full of amino acids and it is one of the best sources of proteins. On the other hand, the plant has a number of valuable vitamins as well. It is the sources of vitamin C and it provides adequate quantities of this vitamin. Thus, if you take care to include theGoji berries in your diet, you could manage to have a lot of vitamins in your diet. Thus, these berries are really valuable from that aspect. 2-Minerals Vitamins and proteins are really important for our nutrition and health. However, the body and mind also needs a number of essential minerals. In that matter, the Goji berries are a rich sources of minerals that provide overall nutrition and health. It is the source for 24 source minerals and carotenoids which are found in veggies like carrots and tomatoes. Also, these berries have minerals like selenium, iron, potassium and other such healthy and nutritious minerals. Thus, if you eat Goji berries to a good extent, you can end up having a number of valuable minerals in your body. 3-Anti-inflammatory and Anti-Bacterial One of the best things about eating the Goji berries is that you can end up having a better protection and security against microbial infections and inflammations. The berries carry many valuable antiseptic properties. These properties end up curing most of your skin inflammations, allergies and bacterial and fungal infection to a great extent. Thus, these berries are known for their antibacterial and medicinal properties and virtues. 4-Antioxidant Properties The berries are also valued across the world for their immense and effective antioxidant properties. The berries can help to reverse the ill effects and degenerative diseases. The antioxidants in the berries keep the deteriorative diseases in good check. Thus, they help to keep the body's immune systems safe and secure from any disease or damage. Thus, the berries should be taken to counter some terrible diseases. 5-Cures Other Problems As a medicine, Goji berries are known for curing a number of well-known and common problems. However, they are also useful in solving problems of the kidney and liver. They also lend a helping hand in curing backache and they make the mind alert and active. This is why they are used to make a variety of tea in China. Goji berries are really valuable plants that should be consumed. They provide all-round protection and security to the body and mind. So, we need to plant Goji berries in our county too.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2673) The Health benefits of L-Arginine
Date:
June 08, 2012 08:10 AM
What is L-Arginine? L-Arginine, also referred to as Arginine, is a non-essential amino acid-it's produced naturally in the body-and it is vital for the normal functioning of pituitary gland. This substance comes from natural sources such as nuts, sesame seeds, sunflower seeds, popcorn, chocolate, brown rice, raisins, carob, oatmeal, gelatin desserts, protein rich foods, and whole wheat bread. Men, whose seminal fluids consist of up to 80 percent of this amino acid, especially need L-Arginine as a deficiency could cause infertility. L-Arginine is not only obtained from food sources but through supplementation as well. As we age, the production of this amino acid decreases in the body and this is thought to cause many degenerative processes associated with aging. Thus, Arginine is vital for maintaining your overall health as well as sexual health. Arginine deficiency Deficiency of L-Arginine can delay sexual maturity, impair insulin production, cause liver lipid metabolism and glucose tolerance. Functions of L-Arginine L-Arginine amino acid performs various functions in the body, including: It is a component of collagen, enzymes, ejaculate, hormones, connective tissues, and skin. It plays an important role in the manufacture of protein molecules such as insulin and creatine. It's a precursor of nitric oxide as well as other metabolites. Health benefits of L-Arginine Although the benefits of Arginine supplements are debated, proponents state that Arginine converts into nitric oxide inside the body and enlarges or dilates the blood vessels. This helps better circulation and it's one of the reasons it is used to cure erectile dysfunction. This amino acid produces positive results as it enhances blood circulation, especially to the genitalia. Arginine is also a key component in sperm and seminal fluid production, so it's used to treat sterility in men. Other health benefits of L-Arginine include: Boosts energy Aids in muscle-building Helps maintain blood-sugar levels Increases immune function Increase fertility in females Improves blood flow and decreases clogged arteries Increases sperm count Helps in liver detoxification Maintains nitrogen balance Promotes body fat burning Promotes better bone density Provides anti-oxidant properties Reduces effects of alcohol toxicity Reduces blood pressure Reduces heart and vascular disease, cholesterol risk and stroke Helps reduce body fat Helps remove excess ammonia Aids faster healing of wounds L-Arginine anti-aging properties One last benefit to note about L-Arginine is the fact that it simulates the production of human growth hormone (HGH), IGF, and testosterone. As your body ages, it produces less and less of these hormones which directly affects the aging process. These hormones are responsible for reducing body fat, keeping the skin elastic, and increasing sexual stamina. While your body won't turn into that of a teenager, taking L-Arginine supplements can make you feel and look younger. Conclusion Just as other forms of supplementation, you should take caution while using L-Arginine. This means that you have to get a doctor's approval before you take this drug. You should carefully follow the drug's instructions on dosage and frequency. As long as you take L-Arginine with care, you can greatly enhance your overall health and wellbeing.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2652) What Is Glutathione Good For?
Date:
April 14, 2012 08:03 AM
What is Glutathione? Glutathione (GSH)is a tripeptide derived from non-proteinaceous amino acids. Contains apeptide bond between the group unusual amino of the cysteine group and the carboxylside chain of glutamate. Glutathione, an antioxidant, helps protect cells from reactive species of oxygen such as free radicals and peroxides. Glutathione is nucleophilic at sulfuracceptors and conjugated electrophilic attack poisonous. Groups thiolare maintained in a reduced state to a concentration of about ~ 5 mM in animal cells. Indeed, glutathione reduces any link disulfideformed with in proteins cytoplasmic cysteines by acting as a donor of electrons.In the process, glutathione is converted to its oxidized form glutathione disulfide (GSSG). Glutathione is found almost exclusively in its reduced form, since the enzyme that turns its oxidized form, glutathione reductase,is constitutively active and inducible to oxidative stress.In fact, the ratio of reduced glutathione to oxidized glutathione in cells is often used scientifically as a measure of cellular toxicity. H2O2+ GSSG + 2 ------- 2GSH H2O.
Advantages of the Glutathione Before discussing the benefits of L-Glutathione, let's first talk a little about the nutrient. Glutathione is an antioxidant enzyme dominant which is soluble in water.It is absorbed mainly in the liver.It helps fight against free radical damage.The free radical damage is harmful relatives. Glutathione is involved in a variety of other functions in the body. The function of Glutathione - Benefits of Glutathione Glutathione works in DNA synthesis and repair, protein and prostaglandin synthesis, and amino acid transport.It helps in the metabolism of carcinogens and toxins.Immune system is improved through the use of Glutathione, and contributes to the prevention of cellular oxidative damage, and activation of enzymes. Glutathione also helps and maintains the functions of other antioxidants. Glutathione deficiency There is the possibility of a deficiency of glutathione. It usually occurs during aging.For example, it is seen in macular degeneration related to age, diabetes, and lung and gastrointestinal diseases. It may be the cause of pre-eclampsia, Parkinson's, AIDS and other neurodegenerative diseases. Where to get Glutathione Some sources of glutathione include fruits such as tomatoes, watermelon, grapefruit, oranges, peaches and cantaloupe.It is found in vegetables such as avocados, potatoes, spinach, okra, acorn squash, and asparagus.It is found in most meats as well. Other sources of vegetables such as broccoli, cabbage, Brussels sprouts, cauliflower, kale, parsley, and not only provide GSH - glutathione peroxidase, but it also stimulates the body to make more BA.Since cooking destroys much of glutathione, you will get more to eat raw or steamed vegetables for the best benefits of Glutathione. Reduced glutathione is in a supplementation that we personally use a company called source naturals a Natural Product meeting the above requirements.The nutrient content in their signature product - Total Balance.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2633) The Major Health Benefits Of Hemp
Date:
April 06, 2012 07:47 AM
Hemp Protein Hemp is the only food with the largest amount of protein available on earth. It is easily digestible and it is the only food with a wide range of proteins. These include important fatty acids and amino acids. It is the only food that supplies the human body with all dietary needs at once. Thus, it is the only food that is capable of sustaining human life alone without other nutritional supplements. Apart from being a good source of proteins, hemp supplies the body with important minerals and vitamins. However, the most important component of this food is the essential fatty acids. These include the alpha-linolenic (omega 3) and linoleic acids (omega 6). These two categories of fat are important in the body because human body is not capable of manufacturing them. Therefore, they have to be consumed in the daily meals. The ratio of omega 6 to omega 3 in hemp is 3:1. This is close to the 4.0 on average as the optimum recommendation of the world health organization for a human diet. It plays an important role in various organs of the body including: Heart health Hemp has important nutrients are that are essential for the good health of the human heart. These are the essential fatty acids which play a very important role in ensuring the health of the heart. Several studies have revealed that substituting saturated fats with healthy polyunsaturated reduced risk of cardiac arrest. Such fats are found in hemp and are important in preventing sudden cardiac arrhythmia. They also reduce levels of cholesterol in the blood. Hemp has important fats that also decrease build-up of cellular in the arteries. This is very important as it is associated with a condition known as atherosclerosis. Phytosterol contained in hemp plays an important role in reducing cholesterol in the blood by about ten percent. Brain health Human brain has a large portion that includes essential fat acids. Since hemp supplies the body with these fats, it becomes essential for brain health. It is also vital for proper memory function. Diseases such as Parkinson's and Alzheimer's are preventable with consumption of hemp. The Omega 3 and omega 6 fatty acids also help in delaying or reducing neurological effects that come with these diseases. This improves the kind of life led by individuals with such diseases. Skin health Essential fatty acids play an important role in ensuring healthy skin. Perhaps, this is why hemp seed has been used as an ingredient in various cosmetic products. The Lipids allow the acids to permeate via the skin. Hemp component in the cosmetic products help to nourish the skin directly. Hemp is also very beneficial to people with psoriasis and eczema skin conditions. These are just the major benefits of hemp in the human body. Others include increasing of metabolic rate and energy levels, improving immunity and organic function, among others. Hemp is also crucial in the prevention of degenerative diseases and this proves why it is crucial for positive human health. This food provides a lasting solution to various health complications and you may as well try it and enjoy its benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2628) How Do Carbohydrate Blockers Like White Kidney Bean Extract Work?
Date:
February 19, 2012 08:14 AM
Weight Loss And Carb Blockers With so many weight loss products available in the market, it becomes difficult to find the right one that actually works. Many dieters are turning to starch blockers such as White Kidney beans that help in reducing the absorption of carbs in the body, hence getting rid of extra flab. Let us look at the science behind starch or cabohydrate blockers. How does Carbohydrate Blocker work? Starch is the non-nutritious and empty calorie form of carbohydrate that is found in bread, pasta, rice and potatoes. These evil foods have become the staple diet of many people. During the process of digestion, all the forms of carbohydrates are converted in to simple sugars. Sugar is further metabolised for energy, and excess sugar is stored either in the muscle tissue and liver or in the form of fat deposits. This breaking down of carbs is done with the help of an enzyme, alpha amylase. Recent studies have found that some substances contain specific ingredients that help in blocking the enzyme amylase. This ingredient is known as Phase 2 Carb Controller and it blocks tha action or function of alpha amylase. This results in slowing down of absorption and digestion processes. This reduces conversion of extra sugar in to fat and hence reduces calorie impact. So actually it is not starch blocker, as they do not block everything; rather it is starch enzymen blocker. White Kidney Beans as Carbohydrate blocker: White kidney beans are large beans that can be used to prepare soup and pasta dishes and other italian dishes. They are also called cannellini beans and have a mild delicious flavor. It has been studies that white kidney beans contain a specific ingredient called Phase 2 Carb Controller that helps in blocking the action of enzyme alpha amylase. According to the latest studies, white kidney beans may help the body stop carbs from breaking down in to sugars, hence there is no excess sugar to get converted in to fat. Experts say that Phase 2 Carb Controller selectively targets only the starchy white component of carbohydrates and do not affect the digestion of healthy carbohydrates such as whole grains and fruits. It inhibits body's digestion of specific complex carbs, which are then eliminated from the body. This helps you get rid of unhealthy stored fat, giving you healthy, fat free body. What are the other benefits of White kidney beans that may assist in weight loss: According to studies, white kidney beans also help in regulating the blood sugar levels. Normal blood sugar levels do not require breakdown of complex carbs and this also helps in losing weight. White kidney beans also contain high amounts of fibre, which aids in digestion and keeps you satisfied, thereby avoiding untimely bingeing of high calorie snacks. Other health benefits of White kidney beans: White kidney beans are useful in lowering triglycerides, coronary artery disease and degenerative arthritis. Clinical studies on white kidney beans or starch blockers have shown that carbohydrate blocker do allow complex carbs to pass through the small intestine undigested. Research is still going on to find the further action of Phase 2 Carb Controller present in white kideny beans in losing weight.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2584) Omega-3 Oil- Learn Why it is So Important for Your Health
Date:
February 13, 2012 09:24 PM
Omega-3 fatty acids are good polyunsaturated fats that are so essential for maintaining excellent health and for our well-being, but unfortunately 8 out of 10 people do not get enough! There are three types of omega-3 fatty acids, EPA, DHA, and ALA. You can get ALA from walnuts and canola oil whereas other two are there in oily fish. Of these three, the best ones are only available from the oily fish. In case of ALA, you would need tons of it to get any desired benefits. Another thing to know about them is that they are essential fats that are not produced within the body, so they have to come from outside source. Lets have a close look at various health benefits of Omega-3 fish oil for you and your family: 1. Cancer prevention-Many studies have revealed that adequate intake of Omega-3 can reduce instances of colon, testicular, ovarian and breast cancer. 2. About thirty percent of brain is actually DHA fat, and when Omega-3 is consumed on regular basis, one can see amazing improvement in concentration and memory. 3 Reverse Heart Disease-Omega-3 helps in reducing instances of plaque build up in arteries. People usually suffer strokes due to atherosclerosis (plaque build up), which get clogged over a period of time in the same way as drains get clogged due to their regular usage. 4. Boosts Immune System- The immune system of body is controlled by essential fatty acids in the regulatory system. Any shortage of Omega-3 fatty acids can lead to the breakdown of immune system. You can reduce various immune disorders by bringing about a balance in the intake of Omega-6 and Omega 3 fatty acids. 5. Fights Various Degenerative Diseases-In degenerative diseases, the structure or function of affected tissues deteriorate over a period of time. You can reduce this process by increasing the consumption of Omega-3 fish oil supplements. They are very beneficial for older people. 6. Increases Fertility-The main reason for infertility in females is the thickening of cervical mucus that impedes the movement of sperms. Aside from that, many vaginal secretions also act as spermicides. In both these cases, deficiency of fatty acids contributes to the problem. Even in males, healthy reproductive and sexual functioning of sex glands is possible only with good concentration of Omega-3 fatty acids in sex glands. 7. Promotes Healthy Skin-Omega-3 fatty acids are important for your skin health. Each skin cell is wrapped up in membrane that consists of substances derived from Omega 6 and Omega 3 fatty acids. Where to get omega-3 You can get Omega-3 from fish oils. You will have to take at lest two servings of fatty fish for required quantities of Omega 3 fish oil. With issues such as toxin and mercury contamination in fish, Omega-3 fatty acid supplements are better alternatives. Why omega-3 fish oil supplements? The best Omega-3 fish oil pills contain purified and concentrated oil without any risk of toxin or mercury contamination. Many reputable manufacturers now provide fish oil capsules with high concentration of EPA and DHA fatty acids with low levels of mercury. You should definitely include Omega-3 fish oil caps in your daily diet to get all the health benefits that your body deserves.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2575) Grape Seed or Pine Bark Extract, Which Is Best?
Date:
October 27, 2011 07:26 AM
Pine Bark Vs Grape Seed ExtractPine Bark Extract and Grape Seed Extract are two well known products that are effectual in combating ADD. Pycnogenol however, is more expensive since it is a patented form of pine bark extract that is being sold in many health stores world-wide. The potent properties of both Pycnogenol and Grape Seed Extract are their proanthocyanidins or flavan-3-ols contents that are normally found in fruits and vegetables. The reason why these chemicals are beneficial is their capacity in aiding vitamin C to work better for the brain. Vitamin C is essential for the production of norepinephrine, serotonin, and dopamine (neurotransmitters involved in ADD). Vitamin C is also useful in providing the body with antioxidants that can help fight free radicals that are very injurious for your health and may lead to a dreadful disease such as cancer. In addition, another role of vitamin C in the body is its capacity to aid the body in chelating detrimental toxic heavy metals by flushing them out from the body. Pine Bark Extract and Grape Seed Extract are also effective natural anti-histamines anti-inflammatory agents and immune boosters. Both extracts are also proven to be influential in terms of regulating enzymes that have significant effects in metabolism. Since the extracts are able to inhibit the breakdown of dopamine and norepinephrine, then it will also lead to a faster reuptake of dopamine.
Active IngredientsProanthocyanidins has been the subject of interest by many researchers in the scientific investigations that they have conducted because of its promising effects that could treat various venous conditions. The compound has been proven to be effectual in strengthening the walls of your capillaries, arteries and veins hence, is very useful in protecting you from ailments that involves the mentioned vital body parts. The benefits of Pine Bark and Grape Seed are already published in many health magazines worldwide as well as in many TV shows like the 60 minutes. The antioxidant content of the extracts derived from Pine Bark and Grape Fruit contains liberal amounts of antioxidants that also acts as an antimugenic agent hence, could prevent DNA mutation. Since the extracts have such innate capability of inhibiting the mutation of DNA, it can be a cure to many chronic degenerative diseases that are caused by environmental mutagens. Another benefit of OPCs is its relevant effects on peripheral venous insufficiency. This specific problem in the legs causes so much pain and discomfort which could also lead to disability. With OPC, relevant improvement in the condition could be noted as evidenced by a decrease in the pain felt, edema and cramps. Comparing both extracts in terms of efficacy is so difficult to determine because Pine Bark Extract and Grape Seed Extract has similar components that are all beneficial to one’s health. The compounds that both extracts have are very useful to one’s health therefore comparing the two would be rootless considering all the health benefits that both extracts could offer.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2528) Can Alpha GPC Really Help With Memory And Growth ?
Date:
September 29, 2011 11:52 AM
What Are The Benefits Of Alpha GPC? L-Alpha Glycerylphosphorylcholine, or abbreviated as Alpha GPC, is a natural compound which is choline in nature. It is considered to be an acetylcholine precursor which is now being studied as a treatment for the degenerative disease called Alzheimer’s disease. This chemical compound also has a parasympathomimetic property and is widely used as a nutritional supplement for enhancing memory and concentration. The other name of Alpha GPC is Choline Alfoscerate. Alpha GPC has the capacity to rapidly transport choline to the central nervous system by passing through the blood - brain barrier. Alpha GPC can be extracted from highly distilled soy phospholipids such as lecithin. Inside the body, this chemical compound can be found in high quantity in neuronal membranes. Some of its benefits are: 1. IMPROVES ACETYLCHOLINE LEVEL. As mentioned earlier, Alpha GPC can cross the blood – brain barrier. Once inside the brain, it positively influences brain activity by enhancing the production of acetylcholine. Acetylcholine is a neurotransmitter which is responsible for improving the individual’s learning process. Acetylcholine acts on both the peripheral and central nervous system. In the former, this neurotransmitter functions as the main neurotransmitter in the autonomic nervous system. It is also involved in the contraction of body muscles. In the latter, acetylcholine acts as an anti – excitatory chemical in the cholinergic system. 2. MEMBRANE COMPONENT. Another health benefit of Alpha GPC is that it can effectively protect nerve cells thus improving the transmission of impulse. Aside from maintaining the integrity of the nerves and nerve cells, Alpha GPC also serves as a precursor of the phospholipids found on membranes. 3. INCREASE HUMAN GROWTH HORMONE. Studies on Alpha GPC have revealed that it can relatively influence the action of the body’s Growth Hormone – Releasing Hormone (GHrH), thus improving the release of growth hormones. In addition, it can also enhance the effects of human growth hormone especially among young individuals. 4. A MODALITY FOR DEMENTIA. Alpha GPC has been long studied for the treatment of senile dementia. Initial result of such studies revealed that patients supplemented with Alpha GPC showed improvement but on a smaller extent. Further studies are still being conducted so that efficacy and safety as well as the appropriate dosage will be determined. 5. INFLUENCES GABA. Studies reveal that Alpha GPC significantly increase the synthesis and release of Gamma Amino – Butyric Acid or GABA. Increased synthesis of GABA is also potentiated by atropine. GABA is considered as the principal inhibitory brain chemical among mammals. It has a significant role in controlling neuronal excitation all over the nervous system. Like acetylcholine, GABA is also one of the primary responsible chemicals for the control of muscle tone. Alpha GPC is formulated as supplement. It is available in 300 to 1,200 milligram oral supplements. Though it is generally safe, it is important that you should consult your doctor first before using this supplement. This would significantly avoid the occurrence of adverse effects and drug interactions. Appropriate dosage will also be determined by your doctor. Remember, any medication or supplement varies from person to person on its therapeutic and adverse effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2468) What Causes Glycine Malabsorption?
Date:
September 09, 2011 04:33 PM
Glycine Glycine is known to be the smallest amino acid in the human body and it is present in both water and fatty based environments. This has been one of the most researched amino acid to date and most results indicate that it has an important role in normal bodily function maintenance. It has the ability to supply collagen to the human body as one of its main functions. Studies have also found that glycine is also used to build both fibrous and muscle tissues which is why it has been used as a treatment for degenerative diseases. Aside from this main function glycine also plays such a wide range of roles in other bodily functions as it is playing a part in numerous system processes, from aiding in blood sugar conversion to affecting the nervous system it truly has made itself essential to the body. That is why any malabsorption or lowering of glycine levels in the body can cause harmful and detrimental effects in any person’s well being. Furthermore, it also has been proven in many studies that glycine has an antioxidant effect which aids in the body’s war against free radicals. In recent years there has been an increase in the popularity of glycine, so much so that some food products have been fortified with it just to up their value in the consumer’s eyes as they know that America is getting more and more health conscious as the days go by. Since the body is capable of producing this substance it is considered as a non essential amino acid. It is seldom that the body will totally run out of this substance however lowered levels due to various reasons are absolutely possible. Which brings me back to how is malabsorption of Glycine caused. Glucose and Galactose Presence Studies have been done to show how glycine absorption can be impaired and what they were able to find out is that there is a competition between forms of sugar like glucose and galactose and glycine for intestinal transport. The results show that there was a decrease in absorption of both substances whenever the other is present. For glycine the drop in absorption was over 50 percent and for the sugars there was also significant decrease in uptake and absorption. What this entails in the real world is that regions with high carbohydrate diets maybe affected and may have cases of Glycine absorption impairment more so than other regions with lower carbohydrate diets however this is not taking into account any gastrointestinal damage that may also affect glycine absorption. Anesthesia Administration In cases that a person has gone through surgery they may suffer from Glycine malabsorption, this is not something to be that worried about as anesthesia is not consistently present in the body and realistically very few individuals have surgery often and surgery that requires anesthesia I might add. Studies have shown that local anesthesia is the one that is more harmful to glycine absorption compared to general anesthesia. If you have a glycine malabsorption problem, supplementing with the amino acid will help restore these low levels. Grab some glycine and feel the difference it can make in your energy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2426) Is Cod Liver Oil Good for My Health?
Date:
July 30, 2011 01:19 PM
Deactivates Pain Chemicals The nutrient profile of cod liver oil makes it an excellent source of eicosapentaenoic acid, or EPA, and docosahexaenoic acid, or DHA. These omega 3 fatty acids have long been identified by scientists as anti-inflammatory compounds. Numerous studies have documented that they exert an inhibitory effect on chemicals that sensitize tissues to pain, cause excessive inflammation, and bring on rheumatism. Nourishes Joint Cartilage Cod liver oil is a traditional treatment for joint pain characteristic of arthritis. In recent years, it has been noted as the leading therapeutic remedy for rheumatoid arthritis and osteoarthritis. Research has shown that it is capable of switching off enzymatic processes responsible for the destruction of cartilage tissue in arthritis. Also, its fatty acid content nourishes the proteins found in joint cartilage. Protects Nervous Tissue The myelin sheaths that insulate the axons of nerve cells located in the brain and spinal cord require fatty acids to support their physiological functions. In particular, DHA is the principal fatty acid that nourishes nervous tissue. Cod liver oil has been utilized as an adjunct medication for multiple sclerosis in studies, and reports suggest its potential as a mainstay of treatment for other neurological disorders. Enhances Brain Function In addition to their known role in the upkeep of myelin sheaths, fatty acids are directly involved in the development of brain function. In fact, they are a major component of breast milk. For years, nutrition experts have suggested consumptions of cod liver oil to combat neurodegenerative disorders as well as enhance cognitive capacities as it contains high levels of compounds proven as effective nootropics. Alleviates Skin Conditions The nutrient profile of cod liver oil is particularly good for the skin. Apart from the fact that it counters inflammatory agents that cause hypersensitive skin conditions, such as eczema and psoriasis, it also promotes tensile strength and maintains skin elasticity. Cod liver oil is a good source of omega 3 fatty acids, essential fatty acids, vitamin A, vitamin, D, and vitamin E, all of which contribute to skin health. Prevents Heart Disease Cod liver oil maintains heart health and even reverses cardiovascular disorders. Medical professionals have supported this nutritional supplement as it has been clinically proven to cut the risk of heart disease. It alters the profile of lipids present in the blood and appears to reduce cholesterol. For decades, lower incidence of cardiovascular disorders has been tied to populations that consume high amounts of cod.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2381) Does Boron Really Help Improve Bone Health?
Date:
July 01, 2011 11:06 AM
Boron and Bone Health
Boron is now widely considered an essential mineral, though its daily value is still a matter of debate. The physiological roles of this chemical element in the human body were unknown in the first half of the 20th century, but in recent years scientific research has proven that it is necessary for the calcium metabolism and vitamin D utilization, both of which significantly contribute to overall bone health. There has not been any figure set in the dietary reference intake for boron largely owing to the fact that its nutritional importance has not been discovered until recently. As a result, important data on the safety of boron intake as a dietary mineral remains under investigation. Nonetheless, the scientific community is convinced that the presence of boron is required for many different metabolic processes. Plants need relatively higher amounts of boron to survive. It follows that plant-based foods are very good sources of dietary boron whereas animal products have negligible amounts of this element. This chemical element was first noted to have a positive effect on joint health. The studies that followed have been observed that boron supplements alleviate symptoms of osteoarthritis in human trials. Promotes Bone Health Concentrations of boron in the synovial fluid and joint cartilage help determine the health of joints and bones. It has been reported that people who have higher amounts of elemental boron rarely develops degenerative joints diseases like osteoarthritis and symptoms of joint pain. Also, epidemiologic studies have shown that populations noted for healthy consumptions of boron have lower incidence of arthritis. More recent studies have shown that boron intake is directly proportional to bone density. For one, it has been documented that supplementation of boron has an impact on bone strength in patients with osteoporosis. Clinical trials have produced very promising results as far as the treatment of bone loss is concerned. There is very good scientific evidence that boron supplements are superior to placebo. Inhibits Bone Resorption The skeletal system is the primary depot for minerals in the human body. Chemical elements obtained from the diet are stored in the bones or otherwise utilized by tissues and organs. In particular, more than half of the overall body concentrations of calcium, potassium, and magnesium are found in the bones, which are constantly remodeled to draw minerals out in response to the needs of body tissues. The process of bone resorption is responsible for releasing the minerals from the bones into the blood. On the other hand, the process of bone resorption takes care of building bone tissue. If consumptions of dietary minerals are insufficient, resorption exceeds formation, as is the case with osteoporosis. The presence of boron promotes mineral retention in the bones, thereby increasing bone mass and density. If you are experiencing osteoporosis, give boron a try!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2356) Improve Immune System, Digestion, Muscle Recover, The Skin, And More with OptiZinc
Date:
May 31, 2011 03:45 PM
Zinc And Your Health.OptiZinc is a patented zinc supplement in which the trace element zinc is bound to the essential amino acid methionine. It is especially formulated to guarantee absorption of zinc at a rate far superior to other zinc supplements. Hence, it is commercially touted to be the form of zinc best suited for people diagnosed with zinc deficiency. Decades-long studies have recorded noticeable effects on health. Increases Immune Function Zinc has long been tied to the immune system. For one, all white blood cells that contain granules in their cytoplasm secrete zinc at certain immune responses. In addition, several other cells in the employ of the immune system utilize zinc signaling for cell-to-cell communication. OptiZinc increases availability of elemental zinc for use by immune cells and modulates immune function in the process. Promotes Healthy Metabolism Zinc is one of the trace elements that are pervasive at the cellular level. Proteins that belong to all enzyme classes necessitate the presence of zinc to activate their catalytic activities. The scientific community has long come to a conclusion that zinc is absolutely necessary for healthy metabolism, and thus the daily zinc needs of the body must be met to avoid impairment of physiological functions. Aids Digestive Processes OptiZinc is particularly good for the gastrointestinal tract. It contains up to 200 per cent of the recommended daily value for zinc to ensure absorption and aid digestion at the same time. Zinc ions are directly involved in the antimicrobial activities that take place in the intestines. Digestive enzymes that contain zinc are responsible for the breakdown of peptide bonds of proteins during digestion. Accelerates Muscle Recovery Supplementation of OptiZinc is likely to benefit people who engage in regular physical activities, especially athletes and bodybuilders. This formulation of zinc contains an equal ration of zinc to methionine, an essential amino acid necessitated in the biosynthesis of many other amino acids. OptiZinc speeds up the recovery of skeletal muscles after subjected to intense exercise. Improves Skin Conditions It is well established fact that a deficiency in zinc leads to higher incidence to acne. Severe cases even result in progressive hair loss and skin ulcer formation. These skin conditions are in fact a symptom of a metabolic disorder affecting the uptake of zinc, whether congenital or acquired. OptiZinc have been reported to alleviate zinc deficiency-induced skin problems and promote healthy-looking skin. Scavenges Free Radicals OptiZinc is a noted free radical scavenger. Its efficacy in preventing oxidative stress has been associated to the prevention of a diverse variety of illnesses, which include eye problems, prostate inflammation, and neurodegenerative diseases. This special formulation of zinc delivers the highest absorbable amounts of zinc into the systemic circulation to effectively prevent radical damage.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2313) The Amino Acid Glycine Is A Component Of Collagen And Essential For Good Health?
Date:
March 23, 2011 03:45 PM
What Is The Amino Acid Glycine And How does it Work In the BodyGlycine is the smallest amino acid found in the human body. It is present not only in water-based environments but also in fatty tissues. Being one of the earliest amino acids to be discovered, it has been a subject of numerous studies in the last century. The abundance of data points to its indispensable role in maintaining the overall health of the body since it is quite ubiquitous at the cellular level. Supplies Amino Acid Requirement of Proteins in Cells It is a widely accepted fact that glycine is an amino acid necessitated for the production of proteins that the human body uses and accounts for more than 30 per cent of the protein group called collagen. Human cells in particular utilize glycine in manufacturing fibrous and muscle tissues, the reason why it has been in use in treatment of degenerative diseases. The total absence of glycine in the human body is impossible, given the role it plays in protein synthesis, but low levels of glycine can be harmful. Converts into Glucose and Helps Regulate Blood Sugar Glucogenic amino acids are a number of amino acids that can be converted into glucose. First on the list is glycine, which does not only aid against a sudden drop in blood sugar but also provides the body with enough glucose to support cellular functions. Feelings of weakness characteristic of fibromyalgia and chronic fatigue are often attributable to an impaired capacity to produce enough energy. The process of gluconeogenesis converts non-carbohydrate compounds into glucose as a response. Displays Inhibitory and Excitatory Neuronal Activities While GABA is the primary inhibitory neurotransmitter in human beings, glycine is also known to display inhibitory activities in the central nervous system. The spinal cord, brainstem, and the forebrain have all been identified to employ this amino acid in gylcinergic neurotransmission, which may be inhibitory or excitatory. It is postulated that glycine plays a major role in various mental disorders, and several studies concerning its psychoactive potential are well underway. Scavenges Free Radicals and Reactive Oxygen Species Although it is not considered an essential amino acid, which means the body produces quantities adequate to support physiological functions, depleting levels of glycine is not uncommon especially in individuals suffering from malnutrition and malabsorption. Glycine supplements have seen a surge in popularity in the latter half of the century as they are also known for their antioxidant activities. Enzymes responsible for antioxidant defenses necessitate glycine, which is an antioxidant in itself. Supplementation of glycine has risen in the past few years especially when studies associating this amino acid to degenerative diseases have started to surface. A number of scientists believed that age-related and other degenerative diseases such as arthritis and osteoporosis may be classified as deficiency diseases in that these diseases can easily be prevented or reversed with diet modifications. The incorporation of glycine in food products has also been reported to contribute to the upkeep of protein complexes needed by joints, muscles, and other parts of the body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2256) How Does Cherry Fruit Extract Help with Gout?
Date:
March 07, 2011 04:39 PM
Cherry fruit extracts contain the micronutrients and phytochemicals found in cherries. They are available as supplements widely touted to display antioxidant and anti-inflammatory properties. Cherries, the fruits, are in fact very high in anthocyanins, which have a long association with the prevention of inflammation, even including the type that results in most known cardiovascular diseases. Also, research on anthocyanins in connection with its chemopreventative potential has yielded the most reliable public data. Individuals suffering from gout will definitely benefit from cherry fruit extracts as supported by an abundance of reports and anecdotal evidence concerning its efficacy.
Stabilizes Metabolism of Purine NucleotidesThe development of gout is greatly attributable to an anomaly in the metabolism processes involving purine nucleotides. A class of organic compounds classified as purines is necessary for life and present in many chemical reactions. They are a major component of ATP, the primary energy of cells, and several nucleotide bases of DNA and RNA are purines. The problem lies in its final metabolic product, uric acid, which at high levels condense into urate crystals that are deposited in tendons and ligaments, as is the case with gout and tophus. Cherry fruit extracts bring about twofold effects. First, they stabilize purine metabolites, notably uric acid, and, second, they facilitate the effective excretion of uric acid. If you consume a lot of foods high in purines such as animal products, especially beef, pork, and seafood, taking cherry fruit extracts will make sure that the uric acid they produce gets out of your system. Affects Releases of Inflammatory Mediators While high levels of uric acid is the causation of gout attacks, the painful inflammation that ensues is triggered by an entirely different group of endogenous compounds in the employ of the immune system. Eicosanoids have long been identified to precipitate pain not only during gout attacks, but in all inflammatory responses of the human body. These compounds are released locally by the cells around the joints containing urate deposits in an attempt to fight off the degenerative effects of uric acid on the surrounding tissues. They deal with the joints the same way they get rid of pathogens during infections, bringing on the redness, swelling, and pain characteristic of gout. A group of bioflavonoids called anthocyanins that are known to interfere with the releases of eicosanoids are abundant in cherries, and intake of cherry fruit extracts deliver these flavonoids into the region of pain. Normalizes Acidic Digestive Environments Cherries belong to the group of foods that are alkaline forming. With gout thriving in an acidic setting, it is just prudent to carefully reassess your diet and cut down on foods high in purines. Not surprisingly, your doctor may tell you to minimize consumptions of meat products especially if you suffer from recurrent gout attacks. Cherry fruit extracts rebalances the pH level of your gastrointestinal tract, and supplementation will keep your body in an alkaline state in the long run, protecting you not only against gout but also against the aging process.
If you suffer from gout or other uric acid buildup disease, give cherry fruit extract a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2248) Why Do We Need Essential Fatty Acids (EFA's) And What Source Is Best?
Date:
February 15, 2011 05:03 PM
EFA's can boost Your HealthEssential fatty acids are organic compounds that the human body necessitates to support healthy functions of organs and tissues but lack the ability to synthesize. Two fatty acids make up this group: (1) alpha linolenic acid, or ALA, and (2) linoleic acid, LA. Also referred to as EFAs, they are ubiquitous at the cellular level, but known to play an active role in neuronal and vascular tissues as well as in inflammation. Maintains Cellular Health One of the most recent advancements in cellular science is the discovery of lipid rafts, which are a part of the bilipid layer of cell membranes specialized for trafficking of cellular molecules, such as proteins and receptors. Also, these lipid rafts have an effect on the viscosity of cell membranes, thereby influencing fluidity that governs membrane-dependent functions of cells such as cellular signaling and phagocytosis, the mechanism by which cells swallow extracellular debris including pathogenic stimuli. Due to its being less stiff and more fluid, essential fatty acids make up cell membranes. Modulates Neuronal Activities It has long been postulated that learning and memory is influenced by the availability of intracellular substances known as endocannabinoids in a process called retrograde signaling. Unlike other neurotransmitters, endocannabinoids act on presynaptic cells while produced in postsynaptic cells, and by so doing enhances the signal transmission between nerve cells. Essential fatty acids are converted into endocannabinoids, which are produced on demand, and thus daily intake of EFA is a must. In addition, EFA has for years been in use as a treatment for depression and in the prevention of neurodegenerative diseases. Regulates Inflammatory Responses The right amounts of essential fatty acids present inside the human body significantly contribute to the inflammatory responses of the immune system. There are chemical compounds that are produced by the body only in the presence of essential fatty acids, and a number of these compounds are essential to the process of healing and other processes implicated during inflammation. This is the reason why intake of EFA is highly regarded as a therapeutic remedy for reducing inflammatory diseases such as arthritis and autoimmune illnesses. Promotes Cardiovascular Health There is high risk of heart attack and related cardiovascular diseases in populations with low levels of essential fatty acids. Especially for individuals who are dependent on drugs that are known to cause oxidative stress in vascular tissues, susceptibility to damages of the blood vessel linings sets the stage for the buildup of macrophages and bad cholesterol in the form of arterial plaques. These plaques contribute to the thinning of the vascular passageways characteristic of atherosclerosis. There is a reason why alpha linolenic acid and linoleic acid are considered essential fatty acids. They are a vital component of a healthy body with well-functioning organs and tissues. Good thing we have a wide list of food sources rich in EFA, which includes the oils of hemp, soya, canola, and wheat germ. EFA is also abundant in seeds of sunflower, chia, pumpkin, and flax.
EFA's should be an essential part of everyone's diet, have you had your EFA's today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2237) Lycopene - A Powerful antioxidant with great promise
Date:
December 10, 2010 06:11 PM
Lycopene
Lycopene is a tetraterpene carotene that is largely responsible for the red color of tomatoes and other fruits and vegetables such as carrots and papayas, although it is not a form of Vitamin A as other carotenes are. It is responsible for the production of the pigment beta-carotene which does have Vitamin A activity, and that is also found in carrots and similarly colored foodstuffs. The health benefits of lycopene have been studied in relation to its possible antioxidant activity and its effect on atherosclerosis and other conditions of the cardiovascular system, and also in its potential anti-cancer properties. Although these properties are still under investigation, there is traditional and anecdotal evidence that is can be used to ward of cancer, heart disease and macular degeneration, a degenerative condition of the retina that results in loss of central vision. It can be taken as a supplement as a form of insurance, even though the firm medical evidence for its use has yet to be established. While not claiming this to be the case with lycopene, many such traditional uses have eventually been proved to have a firm foundation in science, and many of the initial results and studies with lycopene are tending that way.
The Antioxidant Properties of LycopeneCarotenoids tend to possess antioxidant properties, and lycopene is as much a carotenoid as the powerfully antioxidant beta-carotene. The problem is that studies focusing specifically on lycopene are rare, and that while such properties can be assumed by association, they have not been conclusively proved for lycopene. Nevertheless, the health benefits of tomatoes are largely assumed to be due to their high lycopene content, particularly powerful when cooked.
These studies have been inconclusive, although everything is pointing toward lycopene being a powerful antioxidant displaying all the properties of Vitamin A and perhaps more. A lycopene supplement is believed to be safer than Vitamin A which can be toxic in large quantities (300,000UI +), and lycopene is used as an approved food coloring. Have you had your Lycopene today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2206) Glutathion, Antioxidants, And The Body
Date:
July 14, 2010 02:41 PM
Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis. A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids. The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell. Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion. Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well. Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2171) Take Control Of your Inflammation With Supplements
Date:
May 27, 2010 12:40 PM
Chronic inflammation is often induced by uncontrolled oxidative stress (free radical damage). It is the principle mechanism by which degenerative disease takes hold. By reducing oxidative stress and changing the balance within the body to favor the production of anti-inflammatory chemical messengers, one can lower their levels of inflammation. This can be achieved through conscious changes to diet and lifestyle, which includes appropriate supplementation. By consuming foods that are rich in omega-3 essential fatty acids, EPA, and DHA, derived from fish oil or flax seeds, one can greatly influence and reduce inflammation. When the body has appropriate balances of omega-3 and omega-6 essential fats, the production of anti-inflammatory prostaglandins is favored and inflammation is kept in check. Increasing the consumption of foods that are rich in omega-3s or supplementing with a high quality fish oil suppresses the formation of harmful prostaglandins and also promotes the synthesis of beneficial prostaglandins. Since the average North American diet contains 10 to 20 times the amount of omega-6 oils that we need, the most sensibly dietary approach is to reduce sources of omega-6 oils and supplement with a high dose of omega-3 oils in order to achieve the optimal 4:1 ratio of omega-6 to omega-3. Supplementing with flaxseed oil is another effective way to optimize your omega-6 to omega-3 ratio. Anti-inflammatory EPA can be manufactured in the body by converting the alpha-linolenic acid that is often found in flaxseed oil. Supplementing with this oil, along with restricting omega-6 fatty acid intake, raises tissue EPA levels to those comparable to fish oil supplementation. It should even be noted that flaxseed oil contains more than twice the omega-3 fats as fish oil. Additionally, alpha-linolenic acid can be found in a variety of other plant source including pumpkin seeds, walnuts, and other nuts. However, flaxseed is by far the richest source of omega-3 oil, carrying 58% by weight. Another nutrient that plays a crucial role in inflammation is gamma tocopherol. This nutrient acts through a mechanism that is unavailable to alpha tocopherol by reacting with RNO radicals to subdue inflammation. Gamma tocopherol also has the ability to reduce inflammation by inhibiting COX-2 , which is an enzyme that has a central role in the inflammatory process as it controls the synthesis of the inflammatory prostaglandin. The consuption of gamma tocopherol has been found to reduce several other inflammatory protagonists at the site of inflammation. Strong evidence has found that this form of vitamin E exhibits potent anti-inflammatory properties that are extremely important for human disease prevention and therapy. Similar to essential fatty acids is resveratrol and green tea polyphenols each of which have the ability to inhibit the activation of NFkB and control a wide variety of inflammatory pathways. Green tea polyphenols are also believed to be neuroprotective, as they invoke a spectrum of cellular mechanisms such as the chelation of metals, scavenging of free radicals, and modulation of mitochondrial function in nerve tissues. Green tea polyphenols are now considered to be therapeutic agents that can alter brain processes and serve as neuroprotective agents in the progression of neurodegenerative disorders like Alzheimer’s and Parkinson’s disease. There are a wide variety of nutrients that are involved in fighting systemic inflammation. These nutrients and nutrient categories include EPA and DHA, linolenic acid, gamma tocopherol, alpha-lipoic acid, vitamin C, flavonoids, procyanidolic oligomers, and the phenolic compounds found in green tea, turmeric, and olive extracts. When changing your diet from saturated fats to unsaturated fats and adds more fruits and vegetables to their diet along with antioxidant vitamin supplements, one can successfully reduce inflammation naturally and live a healthier happier life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2162) The Good and Bad of an iron supplement
Date:
April 25, 2010 06:04 PM
The dark side of iron supplementation comes when iron is consumed in amounts that are excessive to the body’s needs. Although unbound iron is more likely to cause oxidative challenges through the generation of free radicals, excessive iron supplementation in any form can cause huge problems for the cell. The overload of iron can cause deterioration of the gut lining, vomiting and diarrhea, abdominal and joint pain, liver damage, loss of weight, and intense fatigue. In children, acute doses as low as 3 grams can cause death.
About one out of every 250 North Americans suffer from haemochromatosis, which is a genetic defect that is common in a lot of those people of northern European descent. This disorder causes the body to accumulate and abnormally store high levels of iron. Those people with haemochromatosis store twice as much iron as others, which places them at increased risk for iron-related diseases. Symptoms of these diseases generally occur after fifty years of age and often include things ranging from fatigue, abdominal pain, achy joints, impotence, and symptoms that mimic diabetes. Several studies have produced evidence which suggests that high levels of iron contribute to noticeable increases in the risk for cardiovascular disease. This is likely due to non-haeme iron’s aggressive pro-oxidant nature. Iron levels are one of the strongest biochemical markers for the progression of atherosclerosis, which results from increased oxidation of LDL cholesterol. A study in 1995 conducted on Finnish men found that those who had high body stores of iron also had a substantially increased risk of heart attack. Those men who posses the highest levels of stored iron often showed a levels of risk that was up to three times that of men who possessed the lowest levels of stored iron.
Disorders in iron accumulation contribute to a whole host of other disease states, all of which are degenerative in nature. Studies have shown that chronic iron overload contributes to increased infections, cancer, arthritis, osteoporosis, diabetes, and various congenitive dysfunctions. The only way to remove excess iron is through blood letting, unless you are a woman with regular menses. That is why, for men, iron overload can provide quite a problematic issue. Recent research has found But for those who need iron, it can easily be obtained through a vitamin supplement at your local or internet health food store. Men should avoid iron supplements and products containing iron, but women on the other hand due to monthly blood loss should supplement with iron regularly.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2157) Glucosamine and Joing Pain
Date:
April 05, 2010 04:34 PM
A decline in the amount of glucosamine production occurs along with the normal aging process. This compound is involved in the natural cushioning of the joints, which means that damage and pain can result from a lack of glucosamine. When the natural cushion is gone, the bone and cartilage may rest against each other, which in turn causes deterioration. Not only can this occur in the joints, but it can also occur in the spinal column.
Glucosamine sulfate has proven to be an effective treatment for osteoarthritis. In fact, some have found that this treatment works better than conventional therapies. This is because it does more than just mask the pain. Rather, it actually aids in rebuilding and stimulating joint repair. Also, glucosamine Scientific evidence shows that glucosamine metabolism is altered when osteoarthritis is present within the body. It has been found that glucosamine supplements provide an effective treatment for this condition. Studies, up to this point, have found substantial improvement in those individuals who are treated with glucosamine. There is little risk, if any, involved in the use of glucosamine for the treatment of osteoarthritis. Studies have shown that this compound is very safe and does not possess any known precautions or risks. One study even determined that glucosamine sulfate has the ability to help stimulate the defense mechanisms that are present within the stomach lining. Pain and anti-inflammatory medications, on the other hand, often cause stomach problems such as ulcers.
Glucosamine sulfate has been shown to be an essential part in treating osteoarthritis. Scientific results showed significant improvement in swelling, pain, and degeneration of joints with the use of glucosamine sulfate. Not only is this compound important for reducing the symptoms that are involved with osteoarthritis, but the supplement has been found to actually reverse the degenerative process and induce healing. This compound should be considered to be a form of treatment for osteoarthritis.
It should be noted that when taking this, or any other supplement, one should consult their health care provider before beginning any type of supplementation. Glucosamine may not be recommended in some situations. Do not take glucosamine without first talking to your doctor if you are pregnant or could become pregnant. Similarly, be sure to consult your doctor first if you are breast feeding a baby. For more information on the many beneficial effects provided by glucosamine, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2135) DHEA and Your Health
Date:
March 16, 2010 12:27 PM
When DHEA levels are normal, it aids the immune system in maintaining balance and fighting diseases and infection. This, in turn, protects the body form a variety of serious problems that can occur, including cancer. Although the full extent of DHEA's benefits is not entirely known, there is a great deal of evidence that links low levels of DHEA to conditions such as cancer, Alzheimer's disease, arthritis, osteoporosis, chronic fatigue syndrome, diabetes, fertility problems, lupus, rheumatoid arthritis, multiple sclerosis, allergies, PMS, and even weight problems. Many people even believe that this hormone is the single most important factor in maintaining health.
Scientific studies have determined that individuals with cancer seem to have lower levels of DHEA than those individuals who are healthy. It has been found that DHEA has the ability to inhibit one of the most important enzymes that is responsible for the feeding of cancer cells. Research has also concluded that DHEA can help in a variety of types of cancer, including colon, lung, skin, breast, lymphatic, gastric, prostate, and ovarian. It is believed that DHEA aids in slowing the growth of cancer. This hormone also blocks some of the enzymes that are responsible for cancer proliferation, which helps to prevent the activity of cancer and stops damage from occurring. Alzheimer's condition is extremely frightening, as it deals with the loss of memory and senility. It has been found that levels of DHEA in Alzheimer's patients are forty-eight percent lower than the normal, healthy level established by the control group. DHEA is responsible for protecting the brain cells from damage and deterioration. Also, it is useful with other degenerative conditions that deal with senility. In healthy individuals, DHEA can be found abundantly in brain tissue, which protects against aging and damage. DHEA is a precursor for cortisol and adrenaline, both of which are stress hormones. DHEA can become depleted when the body is under stress due to the effect on the adrenal glands. Because of this, chronic stress can lead to lower levels of DHEA, which can be detrimental to one's health. It has been found the prolonged stress can lead to cases of depression, with depression being helped by the addition of DHEA. Individuals with depression have found favorable results when using DHEA. It has been shown that DHEA therapy is free of side effects when taken in proper amounts. Some problems that occur when excess amounts of DHEA are supplemented include acne, rapid heartbeat, irritability, and headaches. The majority of people solve these problems by lowering the amount they are taking. For more information on the many beneficial effects provided by DHEA, please feel free to contact a representative from your local or internet health food store. Dhea is a hormone naturally found in the body now available over the counter at your local health food store. ~video~
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2130) Vitamins
Date:
March 05, 2009 01:31 PM
Inflammation is a normal part of the body’s defense against pathogens. The increase in body temperature, flood of toxic free radicals and inflammation-signaling proteins, and release of killer macrophage cells are the main signs of an inflammatory event that is the body’s long-established means of defending against a clear and present danger. This adaptive response can now become a cause for debilitating disease. It is even thought that the aging process may be linked to the very defense mechanism that keeps us healthy when we are young. As we grow older, our ability to regulate inflammation begins to diminish. Instead of protecting us, inflammation becomes silent and systemic, allowing degenerative disease to take root. The symptoms of silent inflammation are extremely different from acute inflammation of redness, heat, swelling, and pain, and can lie undetected until it has been around for far too long. Silent inflammation causes the body to turn on itself, as its immune system begins attacking its own organs. Over time, inflammatory cytokines such as C-reactive protein, interleukin-6, and inflammation producing eicosanoids like prostaglandin E-2 and leukotrienes B-4, start to destroy tissue all over the body. In response to this attack, the body produces even more inflammatory cytokines and free radicals, which creates a self-perpetuating cycle. Silent inflammation damages arteries, destroys nerve cells and organs, compromises the immune system, and promotes cancerous growths. Despite how well they feel today, those with silent inflammation are on a fast track toward degenerative disease. On the good side, preventative measures that are taken today to reduce inflammation can prevent degenerative diseases like cardiovascular heart disease, cancer, diabetes, and Alzheimer’s tomorrow. When there are equal numbers of good and bad eicosanoids, a state of wellness is able to prevail within the body. However, when they become chronically unbalanced, many problems result. This balance is, interestingly, highly dependant upon the level of insulin that is found in the body. High insulin levels, whether they are induced by sugar overload, the onset of insulin resistance, or the hormonal effects of excess fat, set the stage for systematic inflammation. As insulin levels climb, oxidative stress increases dramatically, causing the production of inflammatory cytokines. Along with being too high in refined sugar, the average North American diet is filled with inflammation-promoting fats and scarce in inflammation-reducing omega-3 fats; the consequence of this chronic fatty acid imbalance in an increase in systemic inflammation. As inflammation rises, so does the production of cortisol, which is produced in the adrenal glands and is intricately involved in the body’s response to stress. In an attempt to reduce inflammation, cortisol increases blood pressure, elevates blood-sugar levels, and suppresses the immune system. This means that systemic inflammation produces chronically elevated levels of cortisol, which then place a heavy physiological burden on all organs, causing a dramatic increase on the risk of degenerative disease. Fortunately, changing the balance within the body to favor the production of anti-inflammatory eicosanoids can be achieved through a conscious dietary change. By simply increasing your dietary intake of fatty fish, eating raw nuts and grains rich in healthy fats, and supplementing with a high-quality cold-pressed fish oil or flaxseed oil, and concurrently decreasing your intake of red meats, eggs, high-glycemic foods, and foods high in saturated fats, chronic inflammation can be reduced greatly. Vitamin supplements can boost ones antioxidant intake and help fight inflammation as well. Quality vitamins are available at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1974) Turmeric Extract (Curcumin)
Date:
February 10, 2009 01:18 PM
Curcumin is a potent antioxidant and anti-inflammatory that has the potential to provide far-reaching health benefits. It has been shown to be helpful in rheumatoid arthritis, inflammatory bowel disease, pancreatitis, Alzheimer’s disease, heart disease, diabetic retinopathy, and cancer. All of these diseases share underlying inflammation that curcumin may help to diminish. If you have ever eaten curry or cooked with the spice turmeric, you’ve consumed curcumin. It is obtained from the roots of Curcuma longa and consists of several curcuminoids. Turmeric is biologically related to ginger. Curcumin works as an antioxidant, boosting levels of glutathione S-transferase, which is one of the body’s principal antioxidants. This antioxidant blocks the formation of prostaglandin E2, which is a compound that promotes inflammation within the body. Curcumin also inhibits two inflammation-promoting enzymes: COX-2 and 5-LOX. Additionally, curcumin is able to prevent mutations to DNA, which is an effect that helps to maintain younger, healthier cells. A study conducted at the University of Arizona Health Sciences Center in Tucson had researchers using a curcumin rich turmeric extract to treat rheumatoid arthritis in laboratory animals. The extract blocked joint inflammation as well as the breakdown of joint cartilage and bone. It did this by inhibiting the genes that are involved in inflammation. Curcumin also holds tremendous promise in preventing cancer, as well as an adjunct treatment. Studies on animals have found that curcumin can protect against colon, intestinal, oral, and skin cancers. Its benefits come from several mechanisms. First of all, it blocks the cell-growth cycle in cancer cells, which eventually leads to destruction. It also reduces free radicals and inflammation, both of which can lead to cancer-causing cell mutations. Many studies have found that curcumin can protect the liver against a variety of toxic compounds, which is important news for those people who are suffering from liver diseases like hepatitis or cirrhosis. In a recent study, researchers reported that curcumin increased the clearance of creatinine and urea, which are signs of improved kidney function. Additionally, curcumin reduced liver damage from toxic chemicals and excess iron. Another study found that curcumin has the ability to inhibit the activation and spread of the liver cells that play a role in the development of cirrhosis. Japanese doctors have recently used curcumin, drugs, or placebos to treat 89 patients that have ulcerative colitis. These doctors found that a combination of curcumin and conventional medications resulted in the greatest benefits over six months of treatment. Patients in this study took 1,000 mg of curcumin after breakfast and again after dinner. Inflammation is the underpinning of all chronic degenerative diseases, making curcumin likely to be beneficial for many different conditions. So far, research has identified curcumin’s benefits for diabetic retinopathy, lung disorders, and skin problems such as psoriasis. A dose of 3.6 g of curcumin reduced PGE2 levels by two-thirds in only one hour. After consuming curcumin daily for one month, PGE2 levels were 57 percent lower than before supplementation began. Turmeric has been used as a culinary spice for at least 2,000 years. It was listed in an Assyrian herbal in 600 BC, used by ancient Greeks, and widely recommended in Ayurvedic medicine. Native to India and other regions of South Asia, it may reduce the risk of Alzheimer’s disease and help maintain mental function. Curcumin is safe in amounts of 500 to 8,000 mg daily, with most supplements providing 500 mg of curcumin.
Turmeric has been proven safe in larger amounts, but is usually limited by taste as a spice. One should look for a standardized supplement that contains at least 90 percent curcumin. Standardized Turmeric can be found at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1964) Cat's Claw Bark
Date:
December 19, 2008 09:54 AM
We are currently living in a time when vital health issues that greatly affect our families are a huge concern. Cat's claw has been shown to offer a huge array of therapeutic actions, as it is currently drawing a huge amount of attention in health-care. Because cat's claw has anti-tumor, anti-inflammatory, and anti-viral capabilities, it is currently being widely used in Europe for the treatment of cancer, aids, arthritis, and several other degenerative diseases. Cat's claws emergence could not have been better timed, as many people feel that the war on cancer is being lost, with new potentially fatal viruses continuing to evolve and the over-prescription of antibiotics making us even more vulnerable to infection. Recently, taking supplements such as cat's claw is becoming more of the rule than the exception. It is safe to say that almost all of us want to know how to reduce our risk of cancer, protect ourselves from toxins and pollutants, boost our immune system to fight off new viral strains and bacterial diseases, and prevent premature aging and degenerative diseases. Additionally, many of us have found that treating the disease after the fact is much less desirable than the protecting our immune systems, as a well-nourished and healthy immune system can keep us from developing diseases, including cancer. Cat's claw has the ability to fortify immunity, works to scavenge free radicals, and eases inflammation. Cat's claw was traditionally used by Peruvian natives in a variety of applications. They apply its leaves for headaches, use teas for infections including influenza, and have placed plants in antipyretic baths for fevers. Additionally, gargles are used frequently and poultices of the boiled crushed bark have been applied to affected areas. Peruvian tribal medicine has also vigorously rubbed infusions of the raw bark on parts of the body, such as the limbs. The vines of cat's claw are often macerated with a pestle or stems are allowed to stand in water for several hours. In Peruvian culture, snuffing or smoking the dried leaves or bark occurs on occasion. Also, enemas are used in some regions of the tropical South America, but they are relatively rare in the Amazon. Cat's claw can be taken in many forms including a dried, powdered form that is usually available in gelatin capsules; compressed tablets; a decoction or tea; or a liquid suspension that are in the form of gels or extracts, which can often be taken in soft gelatin form. Some experts seem to think that cat's claw extracts have not yet proven their potency and therefore, they recommend taking reliable sources of the plant which use the inner bark of the vine. The alkaloid content of some plants can vary significantly because of many different factors, so only reputable sources of cat's claw are recommended to be purchased. Many studies that have taken place in Europe have shown that cat's claw has extremely low toxicity, even when it is taken in large doses. Anyone who has had a transplant or any pregnant or nursing women should not take cat's claw. Taking cat's claw can potentially cause diarrhea or adjust bowel consistency in some people.
If one is looking for a immune boosting herb from the Amazon look no further, cat's claw can help the sick get well and keep the healthy person free from disease by boosting the immune system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1950) Glucosamine Sulfate
Date:
October 02, 2008 09:36 AM
Cartilage has several roles to play in your body, an example of which is to form curved body parts that would otherwise be unsupported, such as the external contours of your ears or a large part of your nose. Without cartilage you ears and nose would flop around a lot, and it is also contained in the spine, to prevent your discs from grinding against each other. However, the part that we are interested in is as a shock absorber between the bones of your joints. It allows bones to slide over one another without damage, either through friction or shock, and is also nature’s shock absorber, helping to support your weight while you are active. Thus, your cartilage protects from impact damage when you are running or jumping down from a height. This type of cartilage, known as articular cartilage, is bathed in a lubricating fluid known as synovial fluid, which introduces its own problems when your cartilage becomes damaged. This damage can occur in several ways: as the result of a fall, for example, or direct contact with the joint when playing a physical contact sport such as football or soccer. It can also become damaged through wear and tear over a period of time, such with long distance runners or soccer players (again), and is also associated with age. Many years of continual use, especially amongst those with active rather than sedentary occupations, eventually lead to wear and damage. Problems with the joint structure itself, known as osteoarthritis, can also damage the cartilage, as can being overweight for a lengthy period. You can also experience cartilage damage if you are bedridden or other wise immobile for long periods, because the cartilage needs regular movement to function correctly. This is connected with the blood supply, which will be discussed shortly. Cartilage is constructed of cells known as chondrocytes that generate a fibrous matrix known as collagen, a mixture of amino acids known as elastin that allows the cartilage to return to its original shape after deformation, and non-collagenous matrix tissue containing proteins, water and proteoglycans that contain sulfated glycosaminoglycan chains. That last mixture is often referred to as ‘ground substance.’ One of the problems with cartilage is its lack of a direct blood supply, and it relies on the compression and decompression of the articular cartilage, or on the flexing of elastic cartilage, to create a pumping action that drives blood to the chondrocytes. This is why inactivity can cause cartilage damage, due to a lack of blood supply, and why it is repaired more slowly than other body components. Once an injury or wear and tear damages a joint, the body’s natural defense, the immune system, is activated, and the major part of that involved in cartilage damage is the inflammatory response. The joint becomes inflamed, the quantity of synovial fluid is increased to provide more protection and swells the joint, and enzymes (hyaluronidase) are produced which, although part of the natural defense system, actually degrade the synovial fluid and the cartilage. This increases the amount of inflammation and the process becomes self-perpetuating, leading to the condition known as degenerative joint disease (DJD) because the body is unable to produce enough glucosamine to generate the proteoglycan needed for repair. This is where glucosamine sulfate enters the scene. Glucosamine is a precursor for glycosaminoglycans (GAG), which as mentioned as above are components of proteoglycans in the cartilage matrix ground tissue. It has been shown to stimulate the biosynthesis of proteoglycan, and analysis has shown its presence within articular cartilage after administering it orally to patients with cartilage disease. It therefore makes its way to the right place. Glucosamine is administered in the form of glucosamine sulfate, the highly electrically charged sulfate groups believed to aid in the compression properties of cartilage. It is rapidly absorbed into the bloodstream, although only about a quarter of the oral dose is eventually available to the body, and high concentrations accumulate in the liver, kidneys and in articular cartilage where it is used in the biosynthesis of GAG. When in solution, glucosamine sulfate separates into ions: sulfate and glucosamine. Glucosamine ions are involved in the synthesis of GAG, that then combine with proteins to form proteoglycans, a component of the non-collagenous matrix of the cartilage. Although glucosamine is the major active component, there is evidence that the sulfate group contributes the stability of the matrix of the connective tissue since the uptake of sulfate ions increases with the amount of glucosamine sulfate used. Another consideration here is that sulfate is an important part of proteoglycans, and glucosamine sulfate promotes not only the synthesis of glycosaminoglycans, but also of proteoglycans in general. Glucosamine is also active in regenerating the lubricating properties of the synovial fluid, and in hindering the activity of hyaluronidase, the enzyme that breaks down the hyaluronic acid in the synovial fluid.
Some people find that glucosamine, taken either alone or in conjunction with chondroitin sulfate and/or methyl sulfonyl methane (MSM), is more effective than the non-steroidal anti-inflammatory drugs (NSAIDs) used to reduce inflammation (e.g. Aspirin and Ibuprofen) and without the side effects of these substances. MSM contains dietary sulfur, which is necessary for cell structure and healthy cell repair. Methyl sulfone methane is know to be beneficial for painful conditions such as arthritis, and also improves the blood circulation. It might also play a part in helping glucosamine sulfate get to the site of the cartilage damage.
Glucosamine is a large molecule, however, and finds it difficult to make its way to the area around the joint due to the lack of a direct blood supply. It is therefore taken in relatively large doses to ensure that sufficient amounts get to where it is needed. Many people insist that glucosamine sulfate is very effective in reducing, or even eliminating, their pain, and it is finding increasing popularity in the treatment of arthritis and other conditions involving cartilage damage.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1907) Red Yeast Rice
Date:
August 04, 2008 04:07 PM
Many natural substances that are capable of lowering blood fats and cholesterol levels that are potentially harmful have emerged. No one is suggesting that there is a magic pill that will promote healthy cholesterol levels, but nature has provided us with some specific compounds that are capable of enhancing both dietary and lifestyle changes in order to improve cardiovascular health. One of the most impressive of these compounds is that of red yeast rice, which is a fermented food substance that has been traditionally used for its red-coloring abilities in meats and other foods. Additionally, red yeast rice offers some extremely beneficial therapeutic effects, as it is the source of certain compounds that can successfully reduce cholesterol. Pharmaceutical companies have been making cholesterol lowering drugs for many years, but natural supplements are now available which offer the consumer a way to lower cholesterol in natural way. This is extremely good news for those people who are suffering from moderately elevated cholesterol levels and is looking to avoid synthetic drug preparations and the side effects that follow. Most of us are now aware that high serum cholesterol level is what predisposes us to cardiovascular disease along with other degenerative conditions. Learning how to control our cholesterol levels, especially the LDL and blood triglyceride levels, while keeping HDL cholesterol at desirable levels can be an extremely frustrating task. By decreasing our consumption of animal fats and certain types of oils, eating more fiber and taking prescription drugs or natural alternatives, we can easily accomplish our goal. Dietary changes should be targeted first, but turning to cholesterol-lowering prescription drugs has both its pros and cons. Pharmaceutical preparations come with considerable side effects. Some of the drugs that are most effective contain enzymatic inhibitors that prevent the synthesis of cholesterol. Red yeast rice accomplishes the same enzyme inhibition but is considered a natural alternative that safely promotes healthy serum cholesterol levels. Coronary heart disease refers to the damage that is done to the heart when the coronary arteries become blocked or narrowed because of a buildup of plaque or oxidized cholesterol. When cholesterol buildup breaks off and lodges in the heart or brain, this causes a heart attack or stroke. An extremely common disorder of developed nations, coronary heart disease causes more deaths in the US than any other disease. Many people who die from heart disease are ironically in otherwise good health. High blood pressure, which is a related disorder, is similar in the fact that both can be a silent killer. The symptoms of coronary heart disease include impotence, heart attack, or stroke. Although the mortality rates from coronary heart disease have declined over the last twenty years, the reason for this decline is shown to be the better medical technology that is available. Claiming more than one million deaths every year, coronary heart disease is still a major issue facing the American society.
In order to help us prevent heart disease, we have been given many dietary guidelines. However, many of us are not motivated enough to make the dietary changes that could literally save our lives. The major causes of coronary heart disease include obesity, smoking, alcohol, high protein and high saturated fat diet, lack of exercise, high blood pressure, high cholesterol levels, and a genetic predisposition.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1852) What is Alpha Lipoic Acid?
Date:
July 18, 2008 12:36 PM
You can be sure that a supplement has some remarkable therapeutic possibilities when it makes headlines on the five o’clock news. A recent experiment which showed the conditions of rats that had been fed a diet that was totally deficient in vitamin E tested alpha lipoic acid, which caused the rats to return to full health even though no vitamin E was replenished. The results of this test are profound, as giving these rats an alpha lipoic acid caused existing stores of vitamin E that the body was previously unable to use to be regenerated. Alpha lipoic acid is a vitamin-like antioxidant that has been used in Europe for a long period of time. It has recently emerged as an extremely impressive therapeutic agent that scavenges free-radicals. Recent studies have suggested that it has the ability to stop some degenerative diseases, the oxidative process of aging, and restores the health of diseased organs. Additionally, it has the ability to make up deficits of vitamin E or C and could potentially be one of the best treatments that have emerged for diabetes. Alpha lipoic acid (ALA) is considered to be more potent than vitamins E and C, as well as coenzyme Q10. Unlike other antioxidants, ALA has properties that make it superior because it is able to replace certain nutritional supplements, while potentiating others, and inhibiting tissues from deterioration that is associated with diseases. This supplement is also both fat and water soluble, which allows it to protect lipid and aqueous cell structures. Alpha lipoic acid is a compound that is synthesized in small amounts in the body, but can also be supplied from food or supplement sources. A vitamin-like substance, it contains sulfur and also plays a crucial role in energy reactions. It can be found in liver, yeast, spinach, organ meats, broccoli, red potatoes, and red meat. When it is orally ingested, alpha lipoic acid is not compromised in the GI tract or the liver. Numerous studies have been conducted on ALA, all of which confirm its positive effect on metabolic processes, with recent clinical tests supporting its ability to enhance free-radical protection, slow the aging process, and guard against a variety of degenerative diseases. ALA was discovered in the 1930s, where it was originally classified as a vitamin, and later categorized as an essential coenzyme when scientists discovered that it was involved in the energy processes of cell mitochondria. It wasn’t until 1988 that scientists found that it also has powerful antioxidant effects. Alpha lipoic acid is important because it protects us from free-radicals which are present in a body as a result of the number of toxic substances such as auto exhaust, tobacco smoke, pollution, preservatives, and additives that we are exposed to on a daily basis. These free radicals can actually accelerate the aging process, causing premature tissue breakdown to occur. Additionally, our environment will continue to surround us with these pollutants that create free radicals.
There are things we can do to minimize our health risks, which include exercising, eating nutritiously, and not smoking. However, these measures are rarely enough to decrease our risk for certain degenerative disease a substantial amount. ALA is beneficial because it scavenges oxidants that are left behind and helps to convert carbohydrates, fatty acids and protein to energy that is needed to drive muscle movements.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1839) Multiple Vitamins
Date:
June 11, 2008 04:51 PM
Multiple vitamins should be designed with one purpose in mind. They should provide you the ability to properly balance your regular diet with the additional vitamins, minerals, amino acids and antioxidants needed to make your diet nutritionally complete. It is rare that people follow the recommended daily allowances in their regular diets. For this reason, multi-vitamins were developed to provide the missing nutrients to your daily diet. Vitamins designed with this purpose will automatically provide you with the essential additional nutrition you need to boost your health and wellness. The Correct Multi-vitamin Make-Up: A good multivitamin supplement will contain all of the following ingredients. It is designed to balance an average diet and boost health and wellness. * Major vitamins * Minerals * Amino acids * Carotenoids * Tocopherols * Tocotrienols * Antioxidants Antioxidants are an important part of any diet because they attack and neutralize free radicals. These fragments of chemicals are caused by: * Normal metabolism * Pollution * Ultraviolet radiation * Rancid oil * Other toxins Scientists believe that free radicals are one of the elements responsible for aging and degenerative diseases like Alzheimer's, arthritis and cancer. It is because of the nutrient deficiencies in our regular diets that we have become more susceptible to degenerative diseases. Mixed Tocopherols and Tocotrienols: Vitamin E is a series of related compounds. The four main forms are alpha, beta, delta and gamma. Most multi-vitamin supplements only contain large amounts of alpha tocopherol. A healthy diet needs a mixture of them all. When too much alpha tocopherol is induced, gamma tocopherol is depleted. This causes deficiencies because gamma tocopherol is crucial to good health as well. For this reason, it is important that your tocopherol intake is balanced. A mixed intake of all tocopherols is more effective in preventing cardiovascular disease. Tocotrienols are potent antioxidants that complement the alpha tocopherol. The combined nutrients are much more effective at preventing oxidation. This is why you must have a balanced combination of tocopherols and tocotrienols to maintain a healthy diet and a healthy body. To accomplish this you must have a balance of all of the compounds that make up vitamin E. Mixed Carotenoids: These are the red, orange and yellow plant pigments that are found in all of our fruits and vegetables. All of these contain different amounts of carotenoids, but the colors are often hidden by the plant's chlorophyll content. Examples of foods containing large amounts of carotenoids include: * Kale * Collard greens * Swiss chard * Broccoli Tomatoes contain Lycopene, which is a red carotenoid found in tomatoes. It is a potent antioxidant that reduces the risk of prostate cancer. Unfortunately, carotenoids are better absorbed through the ingestion of supplements than from foods. Multi-vitamins usually only contain beta carotene. It is important to find one that contains beta carotene, alpha carotene, lycopene, lutein and zeaxanthin. The Bottom Line: A complete multiple vitamin supplement is necessary as a part of a daily health and wellness regimen. The best multi-vitamin contains a healthy balance of everything listed above in the correct dosages. It is important to do your homework and be sure the multi-vitamin you choose will do its job correctly. Learn as much as you can about your own body's individual nutritional needs. By giving your body proper nutrition, you help it to fight off illness and diseases much more efficiently. A complete multi-vitamin will: * Strengthen your immune system * Decrease your risk of cancer, heart disease and osteoporosis * Increase your level of energy * Elevate your moods * Help you to enjoy a healthier, more productive life Choose a multi-vitamin that has been developed based on the latest science and technology. You will be taking a well-rounded supplement that was designed to properly complement a typical daily diet.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1814) Antioxidants For The Body
Date:
June 10, 2008 11:27 AM
Eating the fruits and vegetables that naturally contain antioxidants is the best way to get them into your system. Mixing them into a well-balanced and healthy diet is the best method of all. This way you reap the benefits of all of the antioxidants in a natural combination. The benefit of dietary antioxidants is that they slow the chemical process of oxidation. This oxidation is what causes narrowing of the arteries and heart-related health problems due to cholesterol deposits. Eating a regular variety of herbs, vegetables and fruits that contain antioxidants is the best way to maintain good health. Some foods that contain antioxidants include:
* Tomatoes Antioxidant supplements are available, lab testing have shown that they are just as effective as their natural counterparts. Natural foods contain ranges of antioxidants that work together synergistically. These combinations of antioxidants are much more effective. More Benefits: Antioxidants and other nutrients are needed by the body to protect against cell damage. They also may reduce the risks of certain forms of cancer. It has been discovered that the mitochondria (cell power plants) are a major source of oxidant production. They are also a target for the damaging effects of the very oxidants that they produce. This is a major cause in the advancement of cellular aging, called apoptosis. It is believed that in apoptosis, each cell has a fixed number of cell divisions that it is capable of. After the cell has used its allotted number of divisions, it ceases to function. Oxidative damage is also a contributing factor of DNA mutation, which causes further malfunction of the cells. Most Common Antioxidants: The following is a list of the most common antioxidants, what benefits they offer and where to find them: *Beta-carotene keeps the skin healthy and promotes growth and development of bones. It also helps to prevent night blindness and fight infection. Beta-carotene is found in vegetables and fruits: carrots, cantaloupe, apricots, broccoli, peppers, tomatoes, spinach, sweet potatoes and pumpkin. * Vitamin C destroys free radicals inside and outside cells. It helps in the healing of wounds, preventing bruising, formation of connective tissue, iron absorption and keeping gums healthy. Vitamin C is being studied for its beneficial effects in reducing cataracts, cancer and heart disease. Foods high in vitamin C include tomatoes, citrus fruits and juices, berries, mango, papaya, peppers, cabbage, spinach, broccoli and potatoes. * Vitamin E acts as the essential fat protector in cell membranes and red blood cells. It reduces the risk of heart disease, cancer and other diseases associated with age. Vitamin E is found in peanut butter, nuts, seeds, vegetable oils, margarine, whole grains, wheat germ, salad dressings and avocado. * Selenium helps the body maintain healthy hair and nails. It also enhances immunity and, along with Vitamin E, prevents cell damage. Vitamin E reduces the risk of cancers, especially prostate, lung and colorectal. The best sources of Selenium include brazil nuts, garlic, meat, eggs, poultry, seeds, seafood and whole grains. The amount of selenium found in plants depends on the soil content in which they are grown. Antioxidants benefit the body by providing a layer of protection for the tissues and cells. They are the front line of the body's protection against free radicals. Free radicals are unstable by-products of oxygen that cause premature aging and degenerative diseases. They also come from environmental sources, such as pollution, UV rays and other toxins. Foods rich in antioxidants help to clean free radicals from the body. They also help to prevent various age-related diseases, cancers and heart disease. Maintaining a healthy, nutritionally balanced body that has the ability to fight disease and infection is a prime way to live a long, disease free and happy life. Regular ingestion of antioxidant rich foods or supplements is the best method to achieve this.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1813) Trace Minerals
Date:
May 09, 2008 11:09 AM
Colloidal trace minerals are just as important to our health and well being as vitamins. Practically since birth we have had it pounded into us that we must eat our vitamins if we are to be healthy. The fact is that vitamins are of little use to you without minerals which are as essential for your metabolism as any vitamin is. The essential minerals are the inorganic equivalents of the essential organic vitamins. They work together to maintain the biochemistry that keeps you alive. Take calcium, for example. That is a mineral needed for healthy teeth and bones, among many other things, but it is no good without vitamin D. Magnesium and potassium are also needed for healthy bones. Take blood clotting: vitamin K is the blood clotting vitamin, but blood will not clot without calcium. How is energy generated in your body from the carbohydrates and sugars that you eat? They are converted to glucose that is converted to energy in every cell in your body and used in-situ. Your heart gets the energy to beat from cells in the heart – energy does not float around the blood waiting to be used. It is generated by means of the production of a substance known as ATP – adenosine triphosphate of which phosphorus is an essential component. Without the mineral phosphate none of us would be alive – nor would any form of life for that matter. ATP is the universal molecule of life. So far we have discussed some of the seven major minerals: calcium, magnesium, potassium, phosphorus, sulfur, sodium and chlorine. There are many more that your body needs, and estimates vary from 45 to 70 trace minerals, without which you would find it difficult to function properly. Although your body can make many of the organic substances needed for life from vitamins, amino acids, fatty acids and proteins, it cannot make minerals which have to be taken in as part of your diet. They must be taken in your regular diet or as a supplement. In the USA a major mineral is one that is needed in amounts greater than 100 mg (0.1g) a day, and trace minerals are required at less than 100 mg a day. So one that is needed at 100.1 is major, and one at 99.9 mg is trace. Is there a difference in the source of trace minerals, or would any source be good enough? The answer lies in the construction of the human body, and the way in which it absorbs minerals. Your body is not designed to absorb metallic minerals. The way that such minerals are available in your diet is as part of larger organic molecules, and this is the way they must be taken as a supplement. Thus, you can’t just drink a soluble metal salt because it will pass straight through you with only around 5% absorption, if it doesn’t poison you first. For supplement purpose, metallic minerals are chelated, or combined with larger organic molecules such as proteins and amino acids, and this increases absorption to as high as 50%. The necessity of trace minerals in the human diet was not discovered, as much as the result of a number of studies on various societies and remedies that appeared to have no basis for their effects. The Hunzas and Azerbaijanis, for example, are known to live very long lives, and investigations into this showed their diet was very rich in colloidal trace minerals from glacial water and food grown in soil enriched by that water. It was through studies such as this and also investigation into the metabolites obtained from liver extracts that indicated the importance of many trace minerals. Take arsenic, for example. A known poison in larger quantities, trace quantities have been found to be metabolized by the liver, and while no studies have been carried out on the use of arsenic as a trace element in human biochemistry, studies on rats and human liver extracts have indicated that it could have a part to play in normal growth and reproduction. Trace minerals take part in many enzyme reactions, and physicians now agree that many health conditions could be enzymic in origin. It follows, then, that trace elements are important in maintaining good health. It is certainly true that we cannot live without any of the seven major minerals. And it is just as certain that many of the trace minerals are just as import to human biochemistry as the major ones. It is certainly true of vegetables, which are less complex biological entities than humans, and if tomatoes need at least eight known minerals for good growth then it is certain that we will need a lot more. No studies are needed to convince us of that. Take zinc, for example. Zinc is essential for proper liver function, wound healing and reproduction: spermatogenesis, the proper development of the primary and secondary male sex organs, and all area of the female reproduction process. Zinc is classed as a trace element, as is selenium, a deficiency of which can lead to heart disease, mental retardation and impaired function of the thyroid. Selenium deficiency is not common in the West but is in China where many areas are depleted of selenium. However, if zinc and selenium are known to be essential, how many of the other seventy or so trace minerals are also essential to human health? The trace minerals in general are believed to protect us from some degenerative conditions, the effects of environmental pollution and help to protect us from the effects of an excessive intake of toxic minerals. Although there have been insufficient studies carried out on most trace minerals, it is known that they should be taken in chelated form, metallic in nature or not. It is also known that such minerals should be taken as a balanced mixture as found in nature. A bullet approach, using an individual mineral to treat a certain condition, could lead to an imbalance in the body, and severe side effects, some of which might not yet be known. What is known is that certain minerals are tolerated by each other in specific relative concentrations, but if this balance is upset then they can inter-react and produce unpleasant side effects on, for example, the delicate balance of minerals in the blood. It is becoming increasingly clear that modern farming methods have resulted in mineral depletion of the soil, and that our normal diet now only contains a small number of the minerals that our forefathers were taking. Plants draw up minerals from the soil when they grow, and we take in these when we consume them or the animals that live on them. Saturation of the soil year in year out by chemical fertilizers low in or devoid of trace minerals has resulted in a sterile environment for our feedstock, and has made colloidal trace mineral supplements almost mandatory for good health. Today’s plants can contain fewer than 20 minerals, compared to the 70 plus of our ancestors. Life expectancy is increasing in spite of our increasingly poor diet rather than because of it, and is due more to medical advances than to advances in agriculture. A mineral supplement does seem necessary, but when you take one it should be balanced so that no one mineral is in excess at the expense of another. This helps to reduce the possibility of overdosing on an individual substance while maintaining a natural balance of minerals in your body to make sure that your normal biochemistry is not interrupted by some deficiency or excess that has yet to be discovered. While this might seem a spurious argument, you can be certain that those in the past that used cadmium and lead as cosmetics would rather have known the effects of these toxic substances that eventually killed them.
So use chelated trace mineral by all means, but make sure that they are balanced and tested so that nothing is present that can upset the normal balance of minerals in your body. If they work for tomatoes they should work for you!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1786) Curcumin, Curcuminoids, and Curamin
Date:
April 30, 2008 10:40 AM
Curcumin, a potent antioxidant and anti-inflammatory, possesses many potentially far-reaching health benefits. After many studies preformed on humans, animals, and in-vitro, it has been found that curcumin may be helpful in rheumatoid arthritis, inflammatory bowel disease, pancreatitis, Alzheimer’s disease, heart disease, diabetic retinopathy, and cancer. All of these previously listed diseases share an underlying inflammation, which can be diminished by curcumin. If you have ever eaten curry or cooked with the spice turmeric, you’ve consumed curcumin. Curcumin, which consists of several curcuminoids, is the active constituent of turmeric, which is used in curry. Turmeric is biologically related to ginger. Curcumin works as an antioxidant by boosting levels of glutathione S-transferase, which is one of the body’s main antioxidants. It also blocks the formation of the prostaglandin E2, which is compound that promotes inflammation within the body. Curcumin also inhibits the activity of nuclear factor kappa beta, which is another substance that is involved in inflammation. Additionally, it reduces the activity of COX-2 and 5-LOX, which are two more inflammation-promoting enzymes. Lastly, curcumin prevents mutations that can result in DNA, which helps to maintain healthier, younger cells. Curcumin taken as a supplement can help with any conditions and diseases including rheumatoid arthritis, cancer, liver and kidney protection, ulcerative colitis, and other inflammatory diseases. A study using a curcumin-rich turmeric extract done at the University of Arizona Health Sciences Center in Tucson, treated rheumatoid arthritis in laboratory animals. The results showed that this extract blocked joint inflammation as well as the breakdown of joint cartilage and bone by inhibiting the genes that are involved in inflammation. Curcumin also holds a great amount of promise in preventing cancer and also as an adjunct treatment. Animal studies have shown that curcumin can protect against colon, intestinal, oral, and skin cancers as its benefits come from several mechanisms. First of all, it blocks the cell-growth cycle in cancer cells, which leads to cell destruction. Additionally, it reduces free radicals by its antioxidant properties, which can lead to cancer-causing cell mutations. Studies have also found that curcumin can protect the liver from a variety of toxic compounds. One recent study left researchers reporting that curcumin increased the clearance of creatinine and urea, which are signs of improved kidney function. It also reduced liver damage from toxic chemicals and excess iron. Japanese doctors have recently used curcumin to treat patients with ulcerative colitis. A combination of curcumin and conventional medications has led to the best benefits over six months of treatment. Since inflammation is the root of all chronic degenerative diseases, curcumin is likely to be beneficial for many different conditions. So far, research has identified curcumin’s benefits for diabetic retinopathy, lung disorders, and skin problems including psoriasis. Turmeric, which is the source of curcumin, has been used as a culinary spice for the past 2,000 years, was used by ancient Greeks, and is now a widely recommended Ayurvedic medicine. It is native to India and other regions of South Asia. By eating a lot of curry, which is rich in curcumin, you may reduce the risk of Alzheimer’s disease and help to maintain mental function. One study proved that people who often ate curry had half the risk of becoming mentally impaired. By eating curry on occasion, the risk of mental decline can be reduced by a little more than a third. Curcumin can be safely taken in amounts from 500 to 8,000 mg daily. Look for a standardized supplement containing at least 90 percent curcumin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1777) Health And Applications Of Coenzyme Q10
Date:
April 17, 2008 02:57 PM
Coenzyme Q10 is a critical cofactor in the biological energy process. It is a powerful antioxidant and plays a vital role in our health and wellness. Coenzyme Q10 is involved in many disease states, consuming adequate coenzyme Q10 can ensure that one maintains good health which can reduce the risk of chronic disease such as the ones listed below: Cardiovascular disease
Neurodegenerative disease
Neuromuscular disease
Many prescription drugs can cause Coenzyme Q10 to deplete especially statin drugs (cholesterol meds). Beta blocking drugs and anti-diabetic drugs can also leach the body of vital Coenzyme Q10 which could lead to the above diseases if left un-checked over time.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1760) Ubiquinol
Date:
April 16, 2008 01:10 PM
Coenzyme Q10 is an important cofactor that is found in nearly every cell of the body. Coenzyme Q10 is naturally produced by the body as well as attained through the foods we eat or in supplement form. With out it, every cell in our body could not produce energy to function and we would die. Coenzyme Q10 has the capability to regenerate antioxidants, protecting cells and DNA from oxidative stress which naturally occurs in the body every day. Some may say that coenzyme Q10 exists in only one form, but in fact this substance exists in at least three forms in the body naturally. These three forms are CoQ ubiquinone, CoQH ubisemiquinone and COQH2 ubiquinol all of which are metabolically active forms of coenzyme Q10. Ubiquinone has been commercially available for more than 30 years normally consumed orally, but recently stable forms of Ubiquinol have been made available for consumption which is of great interest by many researchers. The former ubiquinone when ingested had to be reduced by an enzymatically driven conversion from ubiquinone to Ubiquinol in the digestive tract. This conversion is done by the transfer of electrons effectively reducing the coenzyme Q10 to a more usable form Ubiquinol. Once Ubiquinol is produced the body can more easily manufacture ATP which is directly used by cells for cellular energy. In young individuals, 90 percent of coenzyme Q10 found in the blood is in the Ubiquinol form. This being the case, the old form (ubiquinone) was less absorbable then the newer Ubiquinol that can go right to work in the body. Ubiquinol is considered the strongest lipid soluble antioxidant that is biosynthesized, providing an active defense against oxidative stress that damages, cells, proteins, lipids, and DNA. Some scientists believe that cellular damage from free radicals cause our bodies to age. The older we get the less our bodies produce coenzyme Q10 which in its self is an antioxidant and restores other antioxidants in the body to fight the war against free radicals. Eating foods rich in antioxidants and or supplementing with antioxidants may slow the aging process. With age, disease, and some prescription medications, the old form of coenzyme Q10 can not easily follow the process of absorption in the intestinal tract where it is reduced and shuttled through the lymphatic system into the circulatory system (blood). This is why Ubiquinol was so highly sot after. Ubiquinol is already reduced, the preferred form coenzyme Q10 the body wants to circulate and retain. When one ages, energy levels always drop and one tends to slow down and feel tired sooner in the day, this may be because of a drop in coenzyme Q10 in the blood. Many recent studies suggest that the plasma Ubiquinol ratio is reduced in response to cardiovascular disease, neurodegenerative disease, cancer, fatigue and especially in type-2 diabetes. Supplementing with Ubiquinol can help restore plasma levels and boost ones energy levels and possibly slow diseases. To sum it up, if you are over 45, suffering from a degenerative disease or cancer, feel tired and run down, or taking prescription medications, conventional coenzyme Q10 is not what you want to take to elevate plasma levels. Ubiquinol is needed because the body can not adequately produce the most abundant form of coenzyme Q10 in he blood (Ubiquinol). So for those who want to maintain health and wellness, look for Ubiquinol in their local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1757) Fight Night Blindness, Boost Eye And Vascular Health With Bilberry
Date:
March 19, 2008 09:01 PM
Weakness of blood vessels is often seen during the aging process when blood vessels become fragile. Dark bilberry fruit has been shown to reduce blood vessel permeability, improve capillary resistance, and provide antioxidant properties, to scavenge free radicals. One way to fight the aging process of the body is to promote health in the vascular system by eating nourishing foods, exercising, and learning how to handle stress. Evidence shows that eating five servings or more a day of fruit and vegetables can reduce the risk of heart disease, cataracts, and some other disorders that related to blood vessel health. The dark pigment in fruits and vegetables has many health advantages. A lot of people think that the only way to improve blood vessel health is to reduce blood cholesterol, minimizing the risk of a heart attack. That is an essential goal, but blood vessels should also have strength and integrity to maintain their health in order to carry nutrients and oxygen through the body to feed the tissues. As we age, eye function begins to diminish and causes a lot of people to fear that they are losing their eyesight. The blood vessels decline in function, but there are other factors such as the reduction of arrestin and rhodopsin. Arrestin is a protein while rhodopsin is the light sensitive pigment that can be found in the retina. The dark pigment of fruits and vegetables is extremely important to blood vessels and the health of the structures and proteins of the eyes. Brilliant colored fruits and vegetables may prevent strokes, heart disease, and help long-term vision because they improve integrity of blood vessels. Bilberry fruit has been studied for over 40 years for its supportive effects on blood vessel health, blood circulation, and lymph flow. Blood vessels in the brain, heart, eyes, stomach, veins in the legs, and actually anywhere in the body have the potential to leak. In many regions bilberry extract has been used to support individuals with microcirculatory disorders including varicose veins, atherosclerosis, and degenerative retinal conditions including macular degeneration and cataracts. Diabetes, atherosclerosis, poor diet, lack of exercise, smoking, excess alcohol and an inability to handle stress can all contribute to blood vessel disorders and cause the capillary’s membrane to thicken, therefore, increasing capillary permeability causing edema and leaking of fluid. During the aging process, oxidative damage occurs by free radicals in the eyes, which then causes a loss in the transparency of the lens. Symptoms that occur because of this are blurred vision, increased sensitivity to glare, reduced visual acuity, color perception, and light sensitivity. When the eye structure begins to break down, vision impairment and cataract formation result. Bilberry extract has been shown to improve vision and twilight vision, helping the retina adapt to darkness and glare. With aging, a gradual degenerative process is experienced which is caused by free radical damage to our body’s genetic material, cell membranes, and tissues. Free radicals attack blood vessel endothelial cells, and they begin to rupture. Antioxidants help to prevent AMD and reduce the damage of the retina’s photo receptors. In summary, blood vessel health is an important part of age management. By improving diet, managing stress, exercising, and supplementing with bilberry extract, one can promote the health of blood vessels throughout the body, and therefore, support the eyes.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1726) Boost Skin And Joint Health With Natural Supplements
Date:
January 19, 2008 10:37 AM
A lot of health conscious adults are now attempting to keep a youthful appearance for as long as possible by exercising, taking growth hormone enhances, and using expensive cosmetics. However, studies have proven that the major signs of aging in the skin, joints, and eyes occur due to a progressive collagen and hyaluronic acid degradation in our tissues. Researchers believe that supplementation of these key nutrients can actually reverse sings of aging. Normal functioning of the skin requires that there be normal physiological substances in and around the skin cells. Of the many substances that are required for normal functioning, collagen is one of the most important. Collagen provides structural support to skin, which helps to maintain skin tone, subtleness and elasticity. All of these give the skin its amazing beauty. Without enough collagen, our body would actually lose any connective properties and its ability to hold together, causing the sagging and wrinkles that are associated with age. Hyaluronic acid is also a vital component of the skin's structure. HA is a big part of the space between living cells and is also present in both the dermis and epidermis, where it allows skin to retain moisture and acts as a lubricant between the collagen matrix of the skin. Younger looking skin typically has higher levels of HA, but it has been observed that hyaluronic acid content declines as we age, most dramatically after the age of 50. Most people after the age of 40 have already lost a lot of HA and may require supplementation. High concentrations of hyaluronic acid and chondroitin sulfate are able to reach the corium layers of the epidermis and provide cellar level nourishment to the skin. This then reveals a more vibrant and younger looking complexion. Doctors believe that osteoarthritis affects more than 20 million Americans, with that number reaching 40 million by the year 2020. Some doctors believe we're headed for an epidemic of degenerative joint disease. Osteoarthritis is a degenerative joint condition marked by the erosion of the cartilage at the ends of the bones. Cartilage is the shock absorber of the joint, with regular wear and tear on the joints eventually softening, fraying, and thinning the substance. Other things that can cause cartilage degradation and osteoarthritis have recently been identified by scientists, including: weak quadriceps muscles, eroding cartilage, and changes in bone structure. Certain genes also play a role in predetermining cartilage status, and left untreated and unchecked, this can become extremely debilitating. Since normal joint function requires healthy cartilage and bones, one of the most important substances required for the normal functioning of joints is collagen. As we age, it has been observed that there is a decrease in the production and concentration of collagen in the joints. The lack of this vital structure leads to joint pain and inflammation. Common treatments today include the prolonged use of painkillers and anti-inflammatory drugs, steroids, NSAIDs and COX-2 inhibitors which temporarily relieve pain and cover up the symptoms while the disease moves further. More often, these treatments worsen the condition instead of helping it due to their harmful side effects. A natural supplement containing Collagen II can not only halt the progression of arthritis but can also improve the condition and provide relief to sufferers.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1698) Natural Supplements Like Fish Oils And Phosphatidylserine Can Boost Memory
Date:
January 14, 2008 03:24 PM
We often think of our brain as being different from other organs, but the brain undergoes changes over time, just like the heart. Up until recently, brain aging and everything that goes along with it was associated with neuron failure. Actually, brain neurons do not undergo massive die-off with age. Although some neurons are lost, the brain continues to grow new ones, though at a slower pace. Decreasing cognitive function is now believed to start as early as one's late thirties, which is the result of a lowered vascular function for oxygen and nutrient supply, increased oxidative stress, and decreased production of neurotransmitters. Other issues impact memory too such as normal aging, emotional trauma, alcoholism, depression, seizures, dementias, stroke, neurodegenerative illnesses, and obesity. All of these can lead to devastating changes in mood and memory. Additionally, it is widely known that the use of cholesterol-lowering drugs can severely impact skills that involve brain functions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1688) L-Glutathione Can Eliminate Toxins in the Liver
Date:
December 07, 2007 11:54 AM
L-glutathione is the reduced form of glutathione, and is a tripeptide synthesized in the animal and plant tissues from glycine, cysteine and glutamate. Commonly known as GSH, it contains thiol groups that are maintained in a reduced state, and is a very powerful antioxidant, considered to be the key antioxidant and protective substance in the body. Glutathione can reduce any disulfide groups in the cytoplasm within the body of the cell, and ensures that the cytoplasm is a strongly reducing medium protecting against oxidation. It has a synergistic effect with other antioxidants to protect the body against free radicals and oxidizing agents that cause so much damage to the body through what is commonly referred to as ‘oxidative stress’. However, there is more to it than that and it attaches itself to toxic chemicals and drugs in the liver and renders them into a state suitable for elimination from the body. These toxic materials include poisonous pesticides, hydrogen sulfide, carbon monoxide, heavy metals such as mercury, cadmium and chromium and many other substances that we come into contact with due to present day pollution of our atmosphere and foodstuffs. Glutathione can also help protect the body from the effects of chemotherapy and evidence is suggesting possible links with the control of some cancers, diabetes, atherosclerosis and many other degenerative conditions caused by free radical attack and the effects of pollutants. The way that GSH acts in the cells is that the redox state of the glutathione-glutathione disulfide couple is critical to the health of the intercellular and intracellular fluid. GSH in the reduced state of glutathione reacts with an oxidative agent such as hydrogen peroxide to form the oxidized form, glutathione disulfide and water. It hence mops up oxidizers such as peroxides and free radicals within the cytoplasm of the body’s cells, and also in between the cells. The disulfide is then converted back to GSH by the combined action of the enzyme glutathione reductase and NADPH (the reducing agent nicotinamide adenine dinucleotide phosphate). The cycle then repeats so that two molecules of glutathione continue to reduce damaging oxidizing agents without themselves being consumed. In so doing, the NADPH becomes oxidized. A continuous supply of NADPH is needed to allow GSH to undergo these biochemical reactions, and up to 10% of our blood glucose is used by the pentose phosphate pathway by which NADPH is synthesized. Since this cycle consumes no glutathione, it would appear that a supplement is unnecessary. However, this is not the case since the molecule takes part in other reactions in the body, particularly in the elimination of toxic heavy metals from the body. Mercury is highly reactive with the thiol that GSH is, and so will bind to form a stable Hg-sulfydryl bond in the liver. This mercury-glutathione chelate is unable to bind to other proteins or gain access to the body cells, and is eventually harmlessly secreted. The same is true of many other heavy metals that are reactive with thiol’s. In this way the body is protected from the harmful effects of these heavy metals. However, it results in the loss of the glutathione, and the pollution of modern day living can take a heavy toll of the GSH content of our bodies. For this reason a glutathione supplement is recommended, especially for city dwellers that may be exposed to more heavy metals than those residing in rural areas. However, the form in which this supplement is taken is very important, because the human digestive tract contains a significant amount of gamma-glutamyltranspeptidase. That is an enzyme which apparently destroys glutathione before it can be absorbed. However, it can be absorbed directly into the bloodstream by dissolving the pill between the teeth and inner cheek. It has also been suggestion that the supplement could be administered by injection. Others have suggested that rather than administer a supplement, individuals could take other supplements that contain the materials needed to stimulate the formation of GSH. Substances such as vitamin C, selenium (important in GSH biochemistry), methionine, alpha-lipoic acid and glutamine could all help to increase the body’s production of glutathione. A supplement of the constituent parts of cysteine, glycine and glutamic acid should also help. The dosage ranges recommended vary widely from 50mg to 500mg daily, and the effects of supplementation are not yet well know. Some specific conditions that this wonder antioxidant is useful in treating include liver disease such as hepatitis, cirrhosis and so on. Patients suffering from these diseases show a massive reduction in their GSH content and prior GSH treatment appeared to offer a significant degree of protection in controlled clinical investigations. Patients suffering from chronic hepatitis C have been found to be associated with reduced GSH levels, particularly if also HIV positive. Similar deficiencies have been noted in some lung conditions such as asthma and other pulmonary conditions. In such cases it has been demonstrated that administration of GSH supplements sufficient to restore normal levels of the substance improved the patients’ conditions by a significant amount. Its effect on atherosclerosis appears to be significant since a decreased level of GSH peroxidase has been recorded in such patients in addition to an increase in lipid peroxides, indicating that oxidation of the arterial wall had been occurring. Anti-viral therapies that rely on GSH biochemistry for their action have been found to be less effective in those with low GSH levels, and other studies have confirmed that supplementing with GSH improves the response to interferon treatment. These results indicate the activity of oxidizing agents and free radicals in liver conditions, and in fact this has been demonstrated by tests carried out in New York and Philadelphia in the 1990s. This suggests that the liver is prone to damage by oxidative stress, and that GSH levels may be able to be used as an indication of potential liver disease. What is evident is that a strong case can be made for glutathione supplementation as protection against potential liver, pulmonary and cardiovascular diseases, especially by those exposed to specific polluting agents such as primary or secondary tobacco smoke, auto and diesel fumes and chemicals and pesticides. L-glutathione is useful, not only for the elimination of toxins in the liver, but also in protecting this large and vital organ from the oxidative stress that modern living brings. L-Glutathione and its precursors are sold over the counter at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1649) Milk Thistle May Help With Cirrhosis, Gallstones, and Hepatitis Liver Problems
Date:
November 14, 2007 12:34 PM
Milk thistle, botanically Silybum Adans, is a member of the daisy family that is native to the Mediterranean, the Middle East and North Africa but has also been introduced to California and parts of the eastern side of the USA, and can help with problems such as cirrhosis, gallstones and hepatitis. Although it has been recorded as being used in medieval times as a tonic for the liver, it is only relatively recently that its chemical components have been investigated. Analysis indicated the presence of hitherto unknown flavonoids which were given the name of silymarin. In general, flavonoids are strong antioxidants found in many fruits and vegetables that eat up the free radicals that cause so much damage to our bodies. Free radicals are very unstable molecules that are generated through pollution, such as smoking, car fumes, perticides etc, and that destroy body cells accelerating aging. They also oxidise the low density lipids (LDL) that carry water-insoluble cholesterol through the blood to the arteries where it is needed to repair damage, resulting in excess deposition and the atherosclerosis that can cause strokes and heart disease. Antioxidants mop these up like a sponge, and are some of the healthiest types of molecules that we can consume. The silymarin group of flavonoids are particularly attracted to the liver where they act as antihepatoxic agents that prevent the liver from becoming poisoned. But why should the liver be poisoned I can hear you ask, and what are the poisons involved? Can we avoid them? It is a very relevant question, and one that will make you wonder, every time you leave your home, especially if you live in a big city or an industrialized area. Smoking cigarettes, working with volatile organic compounds that you can breathe in, such as paint and printing ink solvents, the exhaust fumes of cars and diesel engines, factory chimneys belching out tons of smoke, analgesics such as paracetamol, pesticides on your fruit and vegetables that you have failed to wash off, alcohol, etc, etc, etc… All of these have to be removed from your body or you will die, awash with all these poisons that you have ingested, some deliberately and some not. The organ that does this is your liver: the powerhouse chemical plant of your body that carries out millions of biochemical reactions every day. Your liver converts all of these poisons into molecules that can be flushed away through your body naturally. However it places great stresses upon it, and even your liver needs a rest sometimes, or even just a little rejuvenating tonic would keep it happy. Milk thistle has been used for just that purpose, especially when the liver has been toxified with excess alcohol, pesticide poisoning or even hepatitis. The silymarin initially coats the cells of the liver by binding to the cell membranes of the cell walls, so that the toxins are hindered from entering the cells. Its antioxidant properties then neutralise any free radicals present that are causing the damage to the liver cells. It also helps to stimulate the production of proteins to help the healing process, and reduces the fibrosis that is the development of fibrous masses outside the liver cells caused by damaged cells excreting materials such as collagens outside the cells into the general body of the liver. Finally, milk thistle helps to prevent the activity of the immune system in causing inflammation of the damaged cells. Silymarin acts very specifically on the liver, and is often used by physicians in the treatment of such liver conditions as jaundice, hepatitis, liver cancer and cirrhosis. In addition to its own effects it appears that it stimulates the production of glutathione that is also a very powerful natural tripeptide antioxidant produced by the body when it is under oxidative stress. Its effect on cancer and some diseases is not curative, but to allow the liver to continue to detoxify the body when otherwise it might fail and lead to toxicity problems from which the patient might not be able to recover. Due to the remarkable regenerative powers of the liver, milk thistle is able to stimulate it into repairing its damage and grow fresh cells to replace the damaged ones. This is the reason for its effectiveness in otherwise very serious degenerative diseases. It is often prescribed by doctors for patients who are taking a number of different medications. Which help the liver to metabolize these medications, since without it, it might struggle to provide the true efficacy of the prescribed drugs. So far we have been concentrating on the liver, but milk thistle has other properties not connected directly with the hepatic function. It can help to promote the production of bile in the gall bladder and so give the digestive system a boost when needed, where it also acts as a mild laxative. However, it can also help patients suffering from both lose stools and constipation due its effect. It can also help to relieve gallstones, though medical tests are generally carried out first to ensure that they are not too large for the milk thistle to handle. It is also an anti-inflammatory, and is useful in the treatment of acne and other inflammatory responses, and also for inflammations in the gall bladder, kidney and bladder. There are few serious side effects, although, as milk thistle rids the body of toxins, these toxins can cause problems such as diarrhea, headaches and abdominal pain. Keep in mind that you are releasing poisons from the liver into your system so that they can be expelled by the usual means, and they will put up a fight along the way. However, the milk thistle will usually win in the end. There currently appear to be no long term issues with taking milk thistle as a supplement over a long period, and it is good way to maintain a healthy liver. Keep in mind that the liver is the body’s chemical plant, where most of the biochemical reactions of life take place, and without we cannot survive. It makes sense, therefore, to look after your liver, and milk thistle is one way of doing that; some would say the best way.
So remember that, although milk thistle may help with cirrhosis, gallstones and hepatitis liver problems, you should be prepared for a short struggle before it wins the day. Always consult your family physician for a clear diagnosis before self prescribing herbs as treatment. Your physician can advise you as the correct course of action to take once diagnosed with a liver blood test first. But, to boost overall health and wellness milk thistle is a great herbal supplement to take on a daily basis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1631) Natural Vitamin and Herbal Alternatives For Joint Health
Date:
October 18, 2007 03:58 PM
Joint tissue breaks down and arthritis sets in for a number of reasons, and there are several natural alternatives for joint health that can be use to prevent this and to treat affected joints. Thyroid problems can slow down the production of adrenal hormones that are responsible for the production of cortisone and cosrtisol. These are anti-inflammatories, that when unavailable or in low supply can result in joint inflammation. If you suffer joint pain in the mornings that tends to improve as the day goes on, then it is likely that is the cause since adrenal activity can improve as the day progresses. One of the main reasons for joint tissue breakdown is osteoarthritis whereby the cartilage wears down until it fails to provide the necessary protection against impact between the bones in a joint, or against the friction generated when two bones rub together. Injuries to joints can have the same effect, whereby an injury to a hip or knee can appear to clear up and then later the cartilage wears out sooner than expected. This can take several months or many years, depending on the severity and nature of the injury concerned. Continual wear and tear can also cause joint tissue to break down. Athletes and other sportspersons often suffer twenty years or more after retirement from their sport due to the gradual wearing down of cartilage while they were active. Once they stop, this continues to a lesser extent until the cartilage is eventually worn away sufficiently for it to stop protecting the joint. Problems with the auto-immune system can lead to rheumatoid arthritis and inflammation of the joints. This weakens them and can eventually completely destroy the tissue. In such cases the tissues in the joint tend to swell and become extremely painful. Gout can also damage joints, especially in the big toe. This is caused through a built up of needle sharp uric acid crystals. Another cause is a deficiency in sodium and potassium in the diet that are needed to help maintain calcium in solution. When these metals are in deficiency due, for example, to an adrenal problem or some other reason, calcium can deposit right in the joints, causing undue pain. Calcium and vitamin D deficiencies are commonly associated with arthritis sufferers, and protein deficiencies are also believed to be a contributing factor of rheumatoid arthritis, and it is also true that degenerative arthritis can accompany rheumatoid arthritis. This occurs in almost 40% of cases, and diet and nutrition are now being recognized as a major cause of both types. Deficiencies in folic acid or its natural form of folate, vitamin E, zinc and selenium have all been associated with degeneration of joint tissue, so it makes sense that a supplement of these substances can help to avoid these conditions. Standard medical treatment, however, is for the relief of pain and reduction of inflammation through the prescribing of non-steroidal anti-inflammatory drugs (NSAIDs). Typical NSAIDs are aspirin, ibuprofen and naproxen. Although it relieves pain, paracetamol is not an anti-iflammatory. An alternative to blocking the inflammatory reponse is to help to regenerate the damaged joint tissue. However, reducing the inflammatory response to tissue damage does not address the underlying problem, but masks it. Not only that, but there are side effects associated with the use of NSAIDs. Excessive doses can create serious gastrointestinal problems, such as bleeding, ulcer perforation and even death is possible in severe cases. Anti-inflammatories cause gastric problems in up to 20% of cases The newer Cox-2 inhibitors act on the enzyme that causes the inflammation within the joint, and while these can be very effective, they are still masking the underlying problem. Incidentally, the Cox-2 inhibitors should not be used with NSAIDs, and both increase the possibility of a myocardial infarction or heart attack. Also, if you are taking aspirin to reduce the risk of heart problems, you should be careful not to use other NSAIDs since they can interfere with the effects of the aspirin. More effective in the long run is to treat the conditions with substances that deal with the cause of the problem. Vitamin C, for example, improves the lubrication effect of the synovial fluid in the joints, and vitamin E is a strong antioxidant that can help to repair damaged tissue and improve the circulation within the joints. Joints have very low blood circulation levels, which is a problem when trying to direct drugs to the joint tissues. Vitamin C is also good for improving the integrity of connective tissue. Zinc, manganese and copper are also instrumental in developing strong connective tissue and helping to repair the damage done to the joints. Horsetail is a commonly used herbal remedy that can be taken as a tea, tincture or in capsules. It is the richest natural herbal source of silicon, which is used by the body to form connective tissue and collagen. Damaged connective tissue is rapidly repaired by horsetail, and its strength and elasticity significantly improved. It is commonly used in the treatment of arthritis and osteoporosis. Cat’s Claw is used for its beneficial effect on the immune system, and frequently used successfully to treat osteoarthritis and rheumatoid arthritis. However, this treatment is used more to help reduce the inflammatory effects of the condition than to effect a long lasting cure. Gotu Kola, also called Indian pennywort, is traditionally used for treating arthritis. The fresh leaves are effective in reducing the inflammation and pain, and help to improve the quality of life of arthritis sufferers. In Australia, it is referred to as ‘the arthritis herb’ and two leaves a day are said to be effective. Another popular remedy is MSM (methylsulfonylmethane), although it is claimed to provide pain relief rather than a cure. Amino acids also seem to help, and L-cysteine helps promote collagen and connective tissue. It appears to work best when taken in combination with vitamin E and selenium that are powerful antioxidants. L-arginine has a similar effect in the reconstruction of joint tissue, again helping to repair damaged connective tissues. There are therefore two approaches to treating both rheumatoid and osteoarthritis, one providing pain relief and reducing inflammation, and the other repairing the damage done to the joint tissues. Vitamins, minerals, trace minerals and herbal remedies are used in both, though it is better to use a combination that provides pain relief and also helps to regenerate strong connective tissues in the joints. When using combinations of remedies it is important that possible interactions are understood, and you should always seek the advice of your physician when using non-prescription remedies of any kind.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1597) Active Coenzyme Q10 
Date:
July 07, 2007 01:30 PM
Active CoQ10
The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.
In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. What is ubiquinol? Is it the same or different from CoQ10?
A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.
Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?
A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.
So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.
Q. What are the health benefits of CoQ10 and Ubiquinol?
A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.
In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.
Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?
A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.
Q. How might ubiquinol be important for the heart?
A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.
The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.
Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.
The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.
Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.
Q. What have been the results of research studies with Ubiquinol?
A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.
Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Should I take CoQ10 or ubiquinol? How much should I take?
A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.
Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.
Conclusion
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Dental Cavity
Calcium deficiency
What is a PABA
A handful of sunshine everyday is what our body requires to retain its sheen and keep our health problems at bay. Human skin when exposed to ultraviolet rays of the sun manufactures vitamin D-3 orcholecalciferol for its consumption. It is recommended that lighter skin individuals receive 10 to 15 minutes of sunlight daily. Darker individuals, on the other hand, should receive almost double the amount of sunlight, up to 25 to 30 minutes daily. Other best natural food source for vitamin- D3 is fish products, such as: cod liver oil, tuna, salmon and sardines.
What is GABA
Cod liver oil is a dietary supplement obtained from the liver of a group of fishes collectively known as cod. It is an all natural remedy for a diverse variety of disorders, and as such remains one of the most popular supplements to this day. Recent studies have confirmed many of its age-old health claims. It is now common knowledge that it aids joint health, treats skin conditions, and improves brain function. 
Laboratory studies have indicated lycopene to possess strong antioxidant properties, as would also be assumed from its strongly conjugated chemical structure. This would account for its perceived effect upon age-related macular degeneration, and also its possible anti-cancer properties. Several studies have also been carried out using tomato juice in treating atherosclerosis, an oxidative condition involving cholesterol deposition on the internal walls of the arteries. 
Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges. 
Iron holds a crucial role in the physiology of the body. It is a central part of the haemoglobin and myoglobin molecules. Iron is indispensable to the body’s ability to transport gases into and out of the cell. It is necessary in many important enzymes that are involved in energy production, metabolism, and DNA synthesis. Some iron is lost when red blood cells are broken down and excreted in the bile. However, because of iron’s importance, the body is able to conserve iron at all costs, as the kidneys do not eliminate the metal. 
that long-term supplementation with iron at doses less than 5 mg/day can lead to iron-overload toxicity. Because of this, it is recommended that the upper limit of iron intake be at 5 mg/day when considering a product’s rating. Any product that contains iron at a daily dose greater than this limit is penalized with this rating criterion. 
Glucosamine is formed in the body from glucose. This compound is found naturally occurring in the joints of the body. It is important as a precursor and stimulant of the construction of proteoglycan synthesis, which forms the basis of cartilage. Also, glucosamine is important for the synthesis of substances that compose tendons, ligaments, the respiratory system, and the mucous membranes of the digestive and respiratory tracts. 
sulfate therapy helps to prevent joint destruction. Glucosamine sulfate is responsible for helping to heal, relieve pain, reduce inflammation, and improve damage to joint tissue, without causing the side effects that are often associated with drug therapy. 
DHEA is a naturally occurring hormone that is produced within the adrenal glands. The most abundant hormone found in the body, it is sometimes referred to as the “mother hormone.” When hormone levels are too low or out of sync, the body is unable to function as intended. DHEA levels reach their peak in the body around age twenty-one. After that, the levels tend to decline over the years. This substance is a precursor hormone that can be metabolized into other adrenal hormones and act with other hormones. 
