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Glutathione Supplementation Can Boost Your Antioxidant potential and more!
October 27, 2022 10:47 AM
Glutathione is a small peptide molecule composed of three amino acids: Cysteine, glutamic acid, and glycine. It is produced by every cell of the body, with especially high levels in the liver.* Glutathione is critical for healthy immune system function and is necessary for proper detoxification processes.* It also plays a critical role in maintaining cellular health by directly neutralizing free radicals, as well as by maintaining the activity of vitamins C and E.* This product has glutathione in its reduced, active form for optimal bioavailability.*
Glutathione has many benefits, which is why it is often referred to as the "master antioxidant."* It is involved in numerous biochemical reactions in the body, including DNA synthesis and repair, protein synthesis, enzyme activity, and cell signaling.* Glutathione also helps to Detoxify the body by binding to heavy metals and other toxins so that they can be excreted from the body.* In addition, glutathione has been shown to boost energy levels, improve mental clarity and focus, and even promote weight loss.* As you can see, there are many good reasons to make sure you are getting enough glutathione!
How to Increase Your Glutathione Levels
There are a few things you can do to make sure your glutathione levels stay high. First, eat a diet rich in sulfur-containing foods like garlic, onions, eggs, and cruciferous veggies. You can also supplement with N-acetylCysteine (NAC), which is a precursor to glutathione. Taking methylated B vitamins will also help because they are needed for glutathione production. Finally, make sure you are getting enough vitamin C since it is necessary for glutathione recycling.
One of the best ways to increase your glutathione levels is to supplement with Glutathione. This product provides 500 mg of pure reduced L-glutathione per capsule. It is GMO free, vegan friendly, and does not contain any artificial colors or flavors. Glutathione is a pharmaceutical grade product that is manufactured in an FDA-inspected facility in accordance with Good Manufacturing Practices (GMP). With Glutathione, you can be sure you are getting a high quality product that will help you maintain optimal health!
As you can see, there are many good reasons to make sure you are getting enough glutathione. If you want to maintain optimal health, consider supplementing with Glutathione. With 500 mg of pure reduced L-glutathione per capsule, it is one of the most potent products on the market. You can be sure you are getting a high quality product that will help you maintain optimal health! Order your bottle today!
Glutathione: The Most Important Molecule You've Never Heard Of
October 22, 2022 10:17 AM
Glutathione is a small peptide molecule composed of three amino acids: Cysteine, glutamic acid, and glycine. It is produced by every cell of the body, with especially high levels in the liver.* Glutathione is critical for healthy immune system function and is necessary for proper detoxification processes.* It also plays a critical role in maintaining cellular health by directly neutralizing free radicals, as well as by maintaining the activity of vitamins C and E.* Milk thistle extract and alpha lipoic acid are included as complementary ingredients.
What does that mean for your health? In short, glutathione is one of the most important molecules for your overall health and wellness. Read on to learn more about this incredible molecule and how you can make sure you're getting enough of it.
Why You Need Glutathione
Your immune system is your first line of defense against illness and disease. Glutathione plays a critical role in immune system function, so making sure you have enough of it is crucial to maintaining your health. Glutathione is also necessary for proper detoxification processes. It helps your body eliminate toxins and other harmful substances. In addition, glutathione plays an important role in cellular health. It directly neutralizes free radicals, which can damage cells and lead to chronic diseases like cancer. Glutathione also helps keep vitamins C and E active, which are both important for cellular health. Milk thistle extract and alpha lipoic acid are included as complementary ingredients to help support glutathione production.
Getting Enough Glutathione
You can get glutathione from certain foods, such as broccoli, cabbage, spinach, and garlic.* However, the best way to ensure you're getting enough glutathione is to take a supplement. supplements are the most bioavailable form of glutathione, which means they're better absorbed by the body.* Look for a supplement that contains all three amino acids (Cysteine, glutamic acid, glycine) in a 2:1:1 ratio. You should also make sure that the supplement you choose includes milk thistle extract and alpha lipoic acid as complementary ingredients.
Glutathione is a small but mighty molecule that plays a pivotal role in overall health and wellness. If you're not already taking a glutathione supplement, now is the time to start! Look for a supplement that contains all three amino acids in a 2:1:1 ratio, as well as milk thistle extract and alpha lipoic acid. Your body will thank you for it!
Betaine aka TMGs Many Benefits as a Methyl Donor
October 21, 2022 12:29 PM
Methylation is a process in the body that helps to produce DNA, keep hormones in balance, and support detoxification. You need methyl groups for this process to happen, and TMG (trimethylglycine) donates methyl groups to help with methylation. TMG also supports cardiovascular health and cognitive function while reducing inflammation.
Not sure if TMG is right for you? Keep reading to learn more about this methyl donor’s benefits.
Benefit #1: TMG Promotes Healthy Methylation
As we just touched on, one of the main benefits of TMG is that it promotes healthy methylation. As we know, methylation is important for DNA production, hormone balance, and detoxification support.
TMG provides the extra push of methyl groups needed to keep these processes running smoothly which is why it’s often taken as a supplement. If you have difficulty methylating or you have a genetic mutation that affects methylation, TMG may be a good supplement for you to consider. Check with your doctor first, of course!
Benefit #2: TMG Supports Cardiovascular Health
TMG also known as betaine, can improve cardiovascular health by reducing homoCysteine levels. HomoCysteine is an amino acid that at high levels has been linked to heart disease. While more research needs to be done in this area, initial studies are promising.
In one study of nearly 500 participants, researchers found that those who took TMG had lower levels of homoCysteine than those who didn’t supplement with the nutrient . While this doesn’t prove causation, it’s an interesting correlation worth noting—especially given that other studies have found similar results .
benefit #3: May Reduce Inflammation
Chronic inflammation has been linked to many diseases such as heart disease, arthritis, and even cancer. Some studies suggest that TMG may help reduce inflammation levels in the body . In one animal study, rats given TMG had reduced lung inflammation compared to rats who weren’t given the supplement . More research needs to be done in this area but initial studies are promising.
TMG is a nutrient known as a methyl donor which means it provides methyl groups needed for processes like DNA production and hormone balance. It also supports cardiovascular health and cognitive function while reducing inflammation. If you have difficulty methylating or you have a genetic mutation that affects methylation, TMG may be a good supplement for you to consider. Check with your doctor first!
New Formula by Source Naturals: Wellness N-A-Cetin Immune Protocol Contains The Power of NAC & Quercetin for Immune Support
October 19, 2022 03:30 PM
In our quest to discover new immune support strategies, help has come from an unlikely place: NAC & quercetin. Renewed interest has uncovered strong ties to the immune system, which is why Wellness N-A-Cetin™ Immune Protocol offers these ingredients in abundance. Let's take a closer look at how these two substances can help keep your immune system strong.
The Benefits of NAC
N-Acetyl Cysteine (NAC) is a well-known antioxidant with many benefits for overall health. It has been linked to a healthy inflammatory response in lung tissue, and studies show that it also supports a healthy inflammatory response. NAC is often taken as a supplement to help improve respiratory health, and it is particularly helpful during times when we are more susceptible to illness.
The Benefits of Quercetin
Quercetin is a substance found in many fruits and vegetables, especially citrus fruits and berries. It is typically known for its seasonal health benefits, but recent studies have shown that it also supports a healthy inflammatory response. Quercetin is a powerful antioxidant that can help to boost the immune system and protect against cells damage.
This wonderful formula also contains Vitamin C, D-3, Zinc, and Bromelain, which makes for a powerful immune formula.
Vitamin C is one of the most popular immune-boosting ingredients on the market. It's been shown to help fight off colds and other respiratory infections. Vitamin D-3 is another important ingredient for maintaining a healthy immune system. It helps regulate the immune system and has anti-inflammatory properties. Zinc is another vital mineral for keeping the immune system functioning properly. It helps the body create new cells and enzymes, which are needed to fight off infection. Bromelain is an enzyme that helps reduce inflammation and swelling. It's often used as a natural treatment for allergies and sinus infections.
NAC and quercetin found in Source naturals Wellness N-A-Cetin immune protocol are two substances that have many benefits for immune health. They are both powerful antioxidants that can help to boost the immune system and protect against cell damage. If you are looking for a new way to support your immune system, consider adding wellness immune protocol to your daily supplement routine.
Everything You Need to Know About DMG (Dimethylglycine)
October 11, 2022 10:24 AM
DMG (Dimethylglycine) is a derivative of the amino acid Glycine that can be found in foods such as beans, brown rice and pumpkin seeds. DMG is an important methyl donor that participates in numerous biochemical pathways and is important for glutathione synthesis.* It also helps to promote optimal cellular oxygen utilization and supports the production of cells involved in the immune response.* While you may not have heard of DMG before, this compound plays an important role in keeping your body healthy. Read on to learn everything you need to know about DMG.
What is DMG?
DMG is a small molecule that donates methyl groups (CH3). Methylation is a process that occurs throughout the body and is essential for many biochemical reactions, including the production of DNA, enzymes, hormones and neurotransmitters. DMG is involved in methylation reactions involving homoCysteine, folate, cobalamin (vitamin B12) and NADH.*
DMG also supports glutathione synthesis, which is important because glutathione is a key antioxidant that protects cells from damage caused by free radicals.* Furthermore, DMG promotes optimal cellular oxygen utilization and supports the production of cells involved in the immune response.*
Health Benefits of DMG
Because of its involvement in so many biochemical pathways, DMG has a wide variety of potential health benefits. Some of the most well-researched benefits include support for cardiovascular health, brain function and exercise performance.
Cardiovascular Health: DMG has been shown to support cardiovascular health by reducing blood pressure and improving blood flow.* It does this by dilating blood vessels and reducing inflammation.*
Brain Function: DMG has also been shown to support brain function, particularly in aging adults. One study found that supplementing with DMG improved mental clarity, memory and cognitive function in seniors.* The compound may also help improve focus and concentration.
Exercise Performance: Finally, DMG has been shown to improve exercise performance. One study found that athletes who supplemented with Dimethylglycine had increased VO2 max – a measure of cardiovascular fitness – compared to those who didn’t supplement.* Furthermore, another study found that cyclists who supplemented with DMG had reduced heart rate and perceived exertion during exercise.* This suggests that dimethylglycine may help improve endurance exercise performance.
DMG (Dimethylglycine) is a derivative of the amino acid Glycine that can be found in foods such as beans, brown rice and pumpkin seeds. This compound plays an important role in numerous biochemical reactions in the body and has a wide variety of potential health benefits. Supplementing with DMG 100-500 mg per day is generally well tolerated with few side effects reported. If you do experience any adverse effects when taking DMG ramp up your dosage slowly to give your body time to adjust.
New Pure N-acetyl cysteine (NAC) Powder, See the many benefits!
August 19, 2022 11:20 AM
N-acetyl Cysteine (NAC), A Powerful antioxidant, Immune supplement, and much more
If you are looking for a powerful antioxidant and immune support supplement, look no further than Now Foods N-acetyl Cysteine (NAC). This supplement is derived from the amino acid Cysteine, and helps to form protein structures, promote glutathione formation, and support healthy brain and neuronal tissues.* NAC is a stable form of Cysteine that can help maintain normal, balanced immune system function.* So if you are looking for an excellent antioxidant and immune support supplement, consider Now Foods N-acetyl Cysteine!
What is N-acetyl Cysteine (NAC)?
N-acetyl Cysteine (NAC) is a powerful antioxidant that helps protect the body from free radicals. It also helps to maintain healthy levels of glutathione, a critical antioxidant that plays a role in maintaining liver health. NAC has been shown to be beneficial for a variety of conditions, including chronic obstructive pulmonary disease (COPD), bronchitis, and asthma. Additionally, NAC has been shown to be helpful for people with diabetes and those who are obese or overweight.
How does NAC support brain health and neuronal tissues*
Neuroprotection is a property of NAC that supports brain health and neuronal tissues. This is likely due to NAC's ability to scavenge free radicals, as well as its ability to regulate glutamate levels. Additionally, NAC has been shown to increase brain-derived neurotrophic factor (BDNF) levels, which are important for neuron growth, survival, and plasticity. Altogether, these properties of NAC make it an important tool for maintaining healthy brain function.
How does NAC support lung health*?
NAC has long been known for its ability to support the health of the lungs. In fact, it was originally developed as a treatment for tuberculosis. Today, it is still used to help manage lung conditions, including asthma and COPD. NAC helps to improve lung function by clearing out mucus and other debris, and by fighting inflammation. It can also help to protect the lungs from damage caused by pollution and other environmental factors.
How does NAC support respiratory health*?
NAC has been shown to support respiratory health by helping to prevent and clear mucus from the lungs. It can be helpful for people with chronic bronchitis, emphysema, and other respiratory conditions. NAC can also be beneficial for people who smoke or are exposed to secondhand smoke.
What are the benefits of taking Now Foods N-acetyl Cysteine (NAC)*?
Now Foods N-acetyl Cysteine (NAC) is a powerful antioxidant that helps protect cells from damage. It also helps break down mucus and improve breathing in people with chronic obstructive pulmonary disease (COPD). NAC can also help clear up skin problems such as acne and eczema.
Antioxidants to Protect Your Body from Non Ionizing Radiation
July 20, 2022 03:12 PM
Non ionizing radiation is all around us. It comes from many different sources, including our cell phones, laptops, and other electronics. While it is not as dangerous as ionizing radiation, it can still do a lot of damage to our bodies. This damage can lead to health problems down the road. That's why it's important to protect yourself with antioxidants. We will discuss the three best antioxidants to protect your body from non ionizing radiation: vitamin C, NAC, and greens!
What is non ionizing radiation and why should we be concerned about it?
Non-ionizing radiation is a type of electromagnetic radiation that does not have enough energy to remove electrons from atoms or molecules. Despite its relatively low energy, non-ionizing radiation can be harmful to human health. This is because it can cause damage to DNA and other cellular structures. Prolonged exposure to non-ionizing radiation has been linked to an increased risk of cancer, as well as other health effects such as eye damage, skin burns, and interference with the body's natural electrical systems. While the risks associated with non-ionizing radiation are typically lower than those associated with ionizing radiation, it is still important to take steps to reduce exposure when possible. For example, individuals can limit their exposure to non-ionizing radiation by avoiding unnecessary x-rays, using cell phone hands-free devices, and keeping laptops at a distance from the body. By taking these simple precautions, we can help reduce our risk of developing health problems from non-ionizing radiation exposure.
How to protect yourself from non ionizing radiation?
Extended exposure to certain types of non-ionizing radiation can be harmful. For example, prolonged exposure to ultraviolet (UV) radiation can damage the DNA in cells and lead to skin cancer. Additionally, high levels of microwave radiation can cause thermal injuries, such as burns. To protect yourself from harmful non-ionizing radiation, it is important to limit your exposure and take precautions to reduce your risk. For example, you can avoid prolonged sun exposure by wearing sunscreen and staying in the shade. You can also limit your exposure to microwave radiation by avoiding cell phone use and standing at least three feet away from microwave ovens while they are in use. By taking these simple steps, you can significantly reduce your risk of harm from non-ionizing radiation.
The best antioxidants for protecting your body from non ionizing radiation?
When it comes to protecting your body from non ionizing radiation, vitamins C and E are often thought of as the best antioxidants. However, studies have shown that glutathione (GSH) and N-acetyl Cysteine (NAC) may be more effective. GSH is a potent antioxidant that helps to protect cells from damage, and NAC has been shown to increase GSH levels in the body. Both of these nutrients are found in leafy greens, making them an excellent addition to your diet. Green tea is also a good source of antioxidants, and regular consumption has been linked with a reduced risk of cancer. Whether you're exposed to non ionizing radiation on a daily basis or just want to boost your antioxidant intake, adding more greens to your diet is a good place to start.
Other ways to reduce your exposure to non ionizing radiation?
There are a number of ways to reduce your exposure to non ionizing radiation. One is to simply turn off routers and other devices when they are not in use. Another is to move cell phones out of the room where you sleep, or at least keep them on airplane mode during the night. If possible, it is also advisable to avoid using microwave ovens and instead opt for stove-top cooking. Additionally, there are a number of newer devices on the market that emit low levels of radiation, so it is worth doing some research to see if these might be a better option for you. Ultimately, the best way to reduce your exposure to radiation is to be aware of the sources around you and take steps to minimize your exposure.
Non-ionizing radiation is a type of electromagnetic radiation that has been linked to several health risks, including cancer. While the risks associated with non-ionizing radiation are typically lower than those associated with ionizing radiation, it is still important to take steps to reduce exposure when possible. By taking simple precautions, such as avoiding unnecessary x-rays and using cell phone hands-free devices, we can help reduce our risk of developing health problems from non-ionizing radiation exposure. Additionally, there are a number of ways to reduce our exposure to this type of radiation, including turning off routers and other devices when they are not in use, moving cell phones out of the room where we sleep, and avoiding microwave ovens. By being aware of the sources of non-ionizing radiation around us and taking steps to minimize our exposure, we can help protect ourselves from its harmful effects.
How to Support a Healthy Immune System?
May 21, 2022 10:19 AM
It's no secret that a strong immune system is key to keeping you healthy. A robust defense against invading viruses and bacteria can help you stay well all year long, and even support healthy aging. But what are the best ways to support your immune system? Here we will discuss four simple tips that can help keep your immune system functioning at its best!
What is the immune system and what does it do?
The immune system is a complex network of cells and proteins that work together to protect the body from infection. One of the main roles of the immune system is to identify foreign invaders, such as viruses and bacteria, and destroy them. The immune system also helps to remove damaged or abnormal cells from the body, preventing them from causing disease. In order to carry out these functions, the immune system must be able to distinguish between normal, healthy cells and foreign or abnormal cells. To do this, the immune system uses a variety of specialized cell types and proteins. white blood cells are a type of cell that is important in immunity. They circulate through the body looking for foreign invaders and damaged or abnormal cells. When they find these cells, they release substances that destroy them. antibodies are proteins that are produced by the immune system in response to an infection. They attach to foreign invaders and mark them for destruction by other cells of the immune system. The immune system is constantly changing and adapting in order to better protect the body against disease. This process is known as immunization, and it occurs when the immune system encounters and defeats a new virus or bacteria.
The benefits of a strong immune system?
A strong immune system is the key to maintaining good health. It helps the body fight off infections and diseases, and also helps to repair tissue damage caused by injury or illness. There are a number of ways to boost the immune system, including eating a healthy diet, exercising regularly, and getting enough sleep. Additionally, there are a number of supplements that can help to support the immune system, such as vitamin C, echinacea, and garlic. By taking steps to boost the immune system, we can help to protect ourselves against a wide range of illnesses.
Four ways to support your immune system?
There are many ways to support your immune system. Vitamin C is a powerful antioxidant that can help to protect cells from damage. NAC (N-acetylCysteine) is an amino acid that helps to produce glutathione, a key molecule for detoxification. Echinacea is a herb that has been traditionally used to help fight infection. Garlic is a well-known natural remedy that has antibacterial, antifungal and antiviral properties. All of these substances can be found in supplement form, and they can also be found in many foods. For example, citrus fruits contain vitamin C, broccoli and Brussels sprouts contain glutathione-boosting compounds, echinacea can be found in capsules, teas and tinctures, and garlic is a common ingredient in many cuisines. By including these immune-supporting nutrients in your diet, you can help to keep your immune system strong and healthy.
Additional tips for keeping your immune system healthy?
In addition to getting plenty of rest and exercise, there are a few other things you can do to support your immune system. First, make sure you’re getting enough vitamins and minerals. Vitamin C is known for its immune-boosting properties, so consider taking a supplement or eating foods rich in vitamin C, such as oranges, strawberries, bell peppers, and broccoli. You should also make sure you’re getting enough vitamin D, which you can get from spending time in the sun or by taking a supplement. Vitamin E and N-acetylCysteine (NAC) are also thought to support immunity, so consider adding these to your diet as well. Finally, probiotics are “good” bacteria that live in your gut and help keep your digestive system healthy. Probiotics can be found in fermented foods like yogurt and sauerkraut, or you can take them in supplement form. Purchasing a few of these in vitamin supplement form and consuming them daily can ensure you get enough of the needed vitamins to support a healthy immune system. By following these tips, you can help keep your immune system healthy and strong.
A strong immune system is essential for good health. It helps to protect the body against infection and disease, and it also helps to repair tissue damage caused by injury or illness. There are a number of ways to boost the immune system, including taking vitamin supplements, eating a healthy diet, exercising regularly, and getting enough sleep. Are you getting what you need to better support your immunity?
High Fiber Diet May Reduce Risk of Dementia
April 29, 2022 03:54 PM
A high fiber diet may reduce the risk of developing dementia, according to a study published in the journal Neurology. The study found that people who ate the most fiber were 30% less likely to develop dementia than those who ate the least fiber. This is an important discovery, as dementia is becoming increasingly common around the world. There are currently about 47 million people living with dementia, and this number is expected to grow to 135 million by 2050.
What is dementia and what are the symptoms?
Dementia is a general term for a decline in mental ability due to disease or injury. symptoms can vary greatly from person to person, but may include problems with memory, mood, and thinking. People with dementia may have difficulty remembering recent events or familiar faces, and they may become confused about time and place. They may also have trouble completing familiar tasks, such as cooking a meal or getting dressed. As the disease progresses, people with dementia may lose the ability to communicate or take care of themselves. Dementia is not a normal part of aging, and it can affect people of all ages. There is no one test that can diagnose dementia, and doctors often use a combination of medical tests, brain scans, and neurological exams to make a diagnosis. There is no cure for dementia, but there are treatments that can help people manage the symptoms and improve their quality of life.
What causes dementia?
Dementia is a complex neurological disorder with no known underlying cause. While some theories suggest that environmental factors such as exposure to certain toxins or injuries may play a role, the exact mechanisms underlying dementia remain uncertain. Some researchers have proposed that dementia may be related to problems in the functioning of certain proteins in the brain, while others have suggested that chronic inflammation may also be involved. However, there is still much work to be done in terms of understanding the biological mechanisms underlying this debilitating and often devastating illness. Ultimately, identifying the precise causes of dementia will help inform more targeted and effective treatments for this disease, allowing those affected by it to live fuller and healthier lives.
How can a high fiber diet reduce the risk of developing dementia?
A diet rich in fiber has been linked with a reduced risk of developing dementia. Fiber is a type of carbohydrate that the body cannot digest, and it is found in plant-based foods such as fruits, vegetables, and whole grains. Foods high in fiber are known to promote gut health, and some studies have suggested that gut inflammation may play a role in the development of dementia. In addition, fiber-rich foods tend to be high in antioxidants and other nutrients that have been linked with brain health. For these reasons, increasing your intake of fiber-rich foods may help to reduce your risk of developing dementia.
What are some good sources of fiber?
There are many good sources of fiber, including both plant-based and animal-based foods. Psyllium husk, which is made from the soluble fibers found in the seeds of a Mediterranean shrub called Plantago ovata, is a popular option due to its high concentration of dietary fiber and other nutrients. Inulin, meanwhile, is a type of carbohydrate that is naturally found in many fruits, vegetables, and legumes. Both psyllium husk and inulin are excellent sources of nutrition that can help promote good digestive health and overall well-being. Other common sources of dietary fiber include whole grains like oats and barley, as well as beans, lentils, nuts, and seeds. Whether you are looking for plant-based or animal-based sources of fiber, there are plenty of options out there to suit your needs.
How much fiber should you eat each day?
There is no single answer to the question of how much fiber you should eat each day. The amount of fiber that your body needs will depend on a number of factors, including your age, sex, and overall health status. In general, most health experts recommend consuming between 25 and 35 grams of fiber per day. This can typically be achieved by eating a balanced diet that includes a variety of fiber-rich foods, including fruits, vegetables, nuts, seeds, whole grains, and legumes. Furthermore, it is important to remember that fiber needs can vary depending on your symptoms or underlying condition. So if you are experiencing any gastrointestinal issues or other health concerns, it is best to consult with your doctor to determine the right amount of dietary fiber for your body.
Are there any risks associated with eating a high fiber diet?
While fiber is an essential part of a healthy diet, it is important to be aware of the potential risks associated with eating too much fiber. Fiber is a type of carbohydrate that the body cannot digest, and it is typically found in plant-based foods such as fruits, vegetables, and whole grains. When fiber is not broken down by the body, it can bind to other nutrients and substances in the digestive tract and cause them to be eliminated from the body before they are absorbed. This can lead to nutrient deficiencies and other health problems. In addition, consuming large amounts of fiber can also cause bloating and gas.
How can you prevent dementia from developing?
There is no one definitive cause of dementia, but there are a number of risk factors that have been identified as contributing to its development. These can include things like a genetic predisposition, lifestyle factors like drinking and smoking, and certain health conditions. Because these risk factors can vary widely from person to person, there is no one strategy that will prevent dementia in everyone. However, there are some general measures that anyone can take to lower their risk of developing dementia. These might include maintaining healthy eating habits, staying physically active, and avoiding excessive exposure to environmental toxins. Additionally, early diagnosis and treatment for any existing health conditions can also play an important role in reducing the likelihood of dementia. By taking these proactive steps, it is possible to greatly reduce your risk of developing this debilitating condition.
Vitamins and Dementia
Some studies have suggested that certain vitamins may help to prevent dementia. Vitamin B6, B12, and folic acid are involved in the metabolism of homoCysteine, a substance that has been linked to an increased risk of Alzheimer's disease. Vitamin E is an antioxidant that helps to protect cells from damage, and it has been suggested that this may help to slow the progression of dementia.
Fruits and vegetables can help the body combat dementia
Recent studies have suggested that diet may also play a role in the development of dementia. In particular, fruits and vegetables appear to offer some protection against the disease. The antioxidants found in these foods help to fight inflammation and damage to cells, both of which are thought to contribute to the development of dementia. In addition, fruits and vegetables are a good source of vitamins and minerals, which are essential for brain health. Thus, incorporating more fruits and vegetables into your diet may help to reduce your risk of developing dementia.
N Acetyl Cysteine: A Decades-Old Remedy With Many Uses
April 27, 2022 11:53 AM
Did you know that N Acetyl Cysteine has been around for decades? This powerful supplement was first discovered in the 1950s and has been used as a remedy for many health issues since then. We will discuss the many benefits of N Acetyl Cysteine and how you can start using it to improve your health!
Glutathione and aging
As we age, our natural levels of glutathione tend to decline. This is a major cause of many of the negative effects associated with the aging process, including reduced energy and slower recovery times after illness or injury. Fortunately, there are steps that we can take to increase our levels of glutathione, thus slowing down the aging process and keeping us feeling young and vibrant for longer. Some of these steps include eating a healthy diet rich in antioxidant-rich foods like fruits and vegetables, engaging in regular physical activity to improve circulation, and reducing stress levels through relaxation techniques like yoga and meditation. With these strategies in place, we can help to keep our bodies strong, boost our energy levels, and stay young well into old age. Fortunately, there is a supplement that could help, it is called N Acetyl Cysteine, this substance is a precursor to Glutathione and has been shown to boost glutathione levels.
What is N Acetyl Cysteine and what are its benefits?
N acetyl Cysteine has been used as a supplement for many years, and its popularity is likely due to the many benefits it offers. The main function of this compound is to promote the production of glutathione, a powerful antioxidant that protects our bodies from oxidative stress and harmful free radicals. In addition, n acetyl Cysteine has been shown to help reduce symptoms of certain mental health disorders, including anxiety and depression. Furthermore, studies have found that n acetyl Cysteine may lower blood pressure and improve heart health by increasing blood flow and improving blood vessel function. Overall, it is clear that n acetyl Cysteine has been an effective nutrient for many years and continues to be widely used by those looking for an easy way to support their health.
How can you start using N Acetyl Cysteine to improve your health?
N acetyl Cysteine (NAC) is a powerful antioxidant that can help to protect cells from damage. It has been shown to be particularly effective in guarding against liver damage, and is often used as a treatment for hepatitis C. NAC can also help to improve lung function and relieve respiratory conditions such as bronchitis and asthma. In addition, NAC has been shown to boost levels of glutathione, which is a key molecule involved in detoxification. As a result, NAC can help to cleanse the body of harmful toxins and pollutants. NAC is available in supplement form, and can be taken orally or intravenously. It is generally well tolerated, with mild side effects such as nausea and vomiting occasionally reported. When taking NAC supplements, it is important to start with a lower dose and increase gradually as tolerated. Those with pre-existing medical conditions should always speak to their doctor before taking any new supplement. Overall, NAC is a safe and effective way to improve your health and protect your cells from damage.
What is the recommended daily dosage for N Acetyl Cysteine per day?
The standard recommended dosage for N-acetyl Cysteine (NAC) is 600 mg per day. However, some studies have used dosages as high as 2,400 mg per day. The most common side effect of NAC is nausea, which can be minimized by taking the supplement with food. NAC is also sometimes used as a treatment for chronic bronchitis, and the recommended dosage for this condition is 1,200 mg per day. When used for this purpose, NAC is typically taken in divided doses of 600 mg twice per day. There is currently no consensus on the optimal dosage of NAC for any particular condition, and further research is needed to determine the ideal dosage for different applications. In acute circumstances, one might need 4000mg to 6000mgs daily in divided dosages, always work your way up to higher dosages as needed.
What are some of the most common uses for this supplement?
There are many different uses for NAC, or N-acetyl Cysteine. This potent antioxidant supplement has been found to be effective in addressing a wide range of health concerns, including asthma and COPD, chronic sinusitis, liver disease, and particularly serious conditions such as cancer. Additionally, NAC has been shown to provide support for the immune system in general and may also serve as a detoxifying agent by helping to eliminate waste products like heavy metals from the body. Overall, there are numerous benefits to using NAC as part of a well-balanced diet. Whether you are looking to improve your respiratory health or strengthen your immune system, this versatile supplement can help you achieve your goals.
NAC, or N-acetyl Cysteine, is a complex compound that is composed of various amino acids, including glutamate, glycine, and Cysteine. These specific amino acids all play important roles in the function of NAC and affect its many beneficial properties. For example, glutamate increases metabolism and energy levels, while glycine promotes tissue healing and regeneration. Cysteine, on the other hand, facilitates the transport of oxygen and serves as a natural antioxidant. When taken together, these different components work synergistically to promote overall health and wellbeing by supporting key physiological processes such as digestion and immune response. Whether taken as a supplement or consumed through food sources like eggs and milk products, NAC is a versatile substance that is vital to many aspects of our daily health and well-being.
NAC and liver health
N-Acetyl-Cysteine (NAC) is a compound that has numerous benefits for liver health. Studies have shown that NAC can help to protect the liver from damage caused by alcohol and other toxins. It does this by helping to replenish levels of glutathione, a key antioxidant that helps to detoxify the liver. NAC also helps to reduce inflammation and improve blood flow to the liver. As a result, it can be an effective treatment for both acute and chronic Liver diseases. In addition, NAC has been shown to improve the overall health of people with Liver cirrhosis. Consequently, N-Acetyl-Cysteine is a compound that has many benefits for liver health and should be considered as part of any comprehensive treatment plan.
NAC, its sulfur content, and mucus elimination
NAC, or N-acetyl Cysteine, is a sulfur-containing amino acid that plays an important role in mucus production and elimination. The sulfur content of NAC helps to thin mucus and make it less sticky, making it easier to clear from the lungs. In addition, NAC helps to break down mucus and remove it from the body. As a result, NAC is often used as a supplement to treat respiratory conditions such as bronchitis and chronic obstructive pulmonary disease (COPD). NAC is typically taken in the form of capsules or tablets, and the recommended dose depends on the individual. However, side effects are rare and generally mild, making NAC a safe and effective option for those seeking to improve their respiratory health.
N Acetyl Cysteine may lower blood pressure
One of these is its ability to lower blood pressure. A review of several studies found that N-acetyl Cysteine was effective at reducing blood pressure in people with hypertension. In one study, participants who took N-acetyl Cysteine had an average reduction in systolic blood pressure of 9.5 mmHg, compared to those who took a placebo. Other studies have shown similar results, suggesting that N-acetyl Cysteine may be an effective treatment for high blood pressure. While more research is needed to confirm these findings, N-acetyl Cysteine may offer a safe and natural way to lower blood pressure.
N Acetyl Cysteine may help blood clots - thrombosis
Blood clots are a necessary part of the body's natural healing process. They help to stop bleeding by sealing off damaged blood vessels. However, sometimes blood clots can form in healthy blood vessels, causing a potentially deadly condition called thrombosis. N Acetyl Cysteine is a compound that helps to break up blood clots and prevent thrombosis. It works by preventing the formation of a protein that is essential for clotting. In addition, N Acetyl Cysteine helps to improve the flexibility of blood vessels, making them less likely to rupture. As a result, this compound may help to reduce the risk of thrombosis and improve overall cardiovascular health.
Powerful antioxidant helps us burn fat, lose weight and avoid premature aging
April 27, 2019 11:30 AM
Milk thistle is known for being good for the liver, but researchers are finding more and more evidence that points to an antioxidant called glutathione being a key component as well. The powerful antioxidant called glutathione allows our bodies to kick up their natural fat burning abilities which helps trigger weight loss in an almost effortless manner. Studies have also shown that a deficiency in glutathione can cause weight gain through a reduction in mitochondrial fat burning.
"Glutathione is synthesized from the amino acids cysteine, glycine and glutamate. But, as we age, two of these “building blocks” – cysteine and glycine – decline, causing shortfalls in glutathione production."
Read more: https://www.naturalhealth365.com/antioxidant-lose-weight-2793.html
This deficiency often leads to brain shrinkage, psychosis and Alzheimer
April 09, 2019 10:21 AM
There are serious health consequences associated with being deficient in vitamins B3, B6 and B12, including many with neurological or psychiatric elements. B vitamins are very important to healthy brain function, and can also play a role in whether and how quickly diseases like dementia and Alzheimer’s develop. Specifically, being deficient in these vitamins can increase levels of homocysteine, which is associsted with sharply increasing the risk of dementia and Alzheimer’s. Getting enough of the most important B vitamins can suppress homocysteine and help keep your brain healthy.
"It should come as no surprise that nutrition is a foundational consideration to optimize and maintain cognitive function."
Read more: https://www.healthnutnews.com/this-deficiency-often-leads-to-brain-shrinkage-psychosis-and-alzheimers/
Reduces homocysteine levels and acts as an Alzheimers bodyguard?
March 12, 2019 01:50 PM
The prevalence of Alzheimer's is steadily growing, and researchers are growing more and more concerned at the apparent epidemic. Approximately one in six adults will end up experiencing some form of dementia, and this statistic alone is enough to motivate medical experts to find solutions. Some physicians are finding that taking in adequate amounts of omega-3 fatty acids each day can help prevent the stiffening and inflammation of cells that have the potential to lead to a drop in cognitive function related to dementia.
"The influence of marine-based omega-3 fats on physical and mental health has been the subject of intense research for decades, and there’s compelling evidence they can help ameliorate a variety of psychiatric illnesses and degenerative brain disorders, including Alzheimer’s."
Read more: https://www.healthnutnews.com/reduces-homocysteine-levels-and-acts-as-an-alzheimers-bodyguard/
Male infertility can be caused by a taurine deficiency
January 03, 2019 08:50 AM
Scientists recently conducted a study that showed their male mice who had low levels of cysteine dioxygenase were also facing signs of low fertility rates. Cysteine dioxygenase is commonly known as CDO, and some refer to it in the medical field as tourine. Due to the high levels of tourine showing to increase fertility levels in male mice and vice versa, researchers are now presuming that the same may be true for human males facing the same issues.
"The study suggested that a deficiency in taurine, a vital amino acid which is found abundantly in the male reproductive system, can deform sperm and may lead to male infertility."
Read more: https://www.naturalnews.com/2018-12-21-male-infertility-could-be-caused-by-a-taurine-deficiency.html
Reduce your risk of developing an autoimmune disease withglutathione
November 21, 2018 12:15 PM
The 50 million Americans living with some kind of autoimmune disease share a deficiency of “master antioxidant” glutathione. Glutathione helps control and moderate the immune system, and reduce oxidative stress and inflammation, but lifestyle issues like lack of sleep, dietary factors, obesity and inadequate exercise can cause you to developed a glutathione deficiency. Supplements like N-acetyl-cysteine can help increase the amount of glutathione in your cells, while alpha-lipoic acid promotes recycling of oxidized glutathione. You can also address glutathione deficiency by eating a better diet and moderating your blood sugar.
"Research has shown that people with an autoimmune disease are always deficient in this antioxidant."
Read more: https://www.naturalnews.com/2018-10-24-glutathione-reduces-risk-for-autoimmune-disease.html
Health Benefits of Vitamin B9
September 01, 2018 09:53 AM
Vitamin B9, which naturally occurs in food as folate and is artificially added to food in the form of folic acid, is a crucial and versatile nutrient. Natural dietary sources include green, leafy vegetables, liver and mushrooms, but many other foods can be fortified with Vitamin B9 in the form of folic acid. Vitamin B9 plays an important role in cardiac health, mood, production of red blood cells and other bodily processes. It is also very important during pregnancy, when a deficiency can harm both mother and baby.
"Vitamin B9 is a member of the B-vitamin family and is essential for amino acid metabolism, cellular homeostasis, DNA methylation and neurotransmitter synthesis."
Read more: https://www.healthaid.co.uk/healthaid-blog/vitamin-b9-benefits
Vitamin B6 Benefits, Food Sources, Dietary Allowance & Deficiency
May 22, 2018 05:16 PM
Pyridoxamine (aka Vitamin B6) is a water soluble vitamin of the B Complex family with a range of important nervous system and stress regulation functions. B6 helps regular immunity, protect the skin, prevent cognitive decline (especially in seniors) and provide for a steady, healthy emotional state and sleep cycle. Foods rich in B6 run the gamut from plant-based sources like chickpeas, tofu, brown rice and avocados to beef liver, chicken breast, yellow tuna and other animal sources.
"In the research test groups, it was shown that Vitamin B6 benefits cognitive health in such a way that it can significantly reduce serum total homocysteine (tHcy) levels. This process is especially helpful when B6 is taken in supplement form; even then, it can better aid cognitive health when used alongside additional vitamins such as B12."
Read more: https://healthyfoodmaster.com/vitamin-b6-benefits-food-sources-dietary-allowance-deficiency/
Vitamin B12: 4 Health Benefits, 4 Symptoms Of Deficiency, And 4 Foods To Eat
February 20, 2017 10:59 AM
This gives you the scoop on vitamin B12. It lets you know four benefits of it, exactly what it does with the body, and it also tells us what to look for if we're not getting enough. You also learn about four foods that will help you get more of this essential vitamin.
"Vitamin B12 is an essential nutrient that’s involved with a lot of important processes in the human body."
Nourish your bones with vitamins - The Detroit News
December 13, 2016 06:59 AM
Bones are constantly being broken down and rebuilt to make it stronger. To decrease the chance of the "replacement bones" of being weaker, there are a few vitamins that will make your bones stronger. These vitamins include Vitamin D, Calcium, Magnesium, Vitamin K, Vitamin B12, and Folate. These vitamins can be taken in pill form or be found in certain foods.
"Vitamin B12 and folate support bone health by helping to keep levels of homoCysteine, a compound that stimulates the breakdown of bone, low. This role is further confirmed by genetic studies that reveal a link between an increased risk of osteoporosis in older adults and a common gene mutation (MTHFR C677T) that can lead to high homoCysteine levels."
Improving Liver Health - Does NAC Help Improve Liver Health?
September 25, 2015 01:33 AM
All organs in our body have purposes why they exist. This includes our football size liver. Many people take their liver health for granted. Since it is an internal organ, we do not see the actual effects of toxins and unhealthy lifestyle as they slowly destroy the liver. However, we might feel the results from time to time. Our liver has the size of a football, making it a star football player in our digestive system where everything passes through it. It cleanses the blood by taking away hazardous chemicals, converting the liquid into bile, which is then used to break down fat from the food we eat. The liver also stores glucose, a sugar that quickly boosts energy. So how do we take care of our liver?
How to Take Care of Liver Health
It is okay to enjoy and have fun, but to do it every day with a lot of alcohol is dangerous. Drinking too much alcohol leads to the swelling of liver cells.
Controlling what you eat and good amount of exercise will help you avoid non-alcoholic fatty liver diseases, a condition that might lead to severe liver damage.
There are some medicines such as Tylenol and cholesterol drugs that may hurt your liver when taken in uncontrolled doses. Also avoid taking medicines with alcohol, because they are not a good combination, or joining different drugs together.
Many studies say that liver diseases are caused by the lack of Glutathione or GSH in our body. That is why NAC comes to the rescue.
NAC is a small protein powerful to restore intracellular level of Glutathione or GSH, an effective antioxidant. The GSH is most needed by those who have liver diseases because it protects the liver against toxicity. When you are suffering from stress caused by a chronic liver disease, there is the reduction of glutathione, which is why there is a need to supplement it. NAC also helps to protect against present liver damages by reducing a wide range of chronic, deteriorating issues which include liver inflammation and impaired glucose control.
Taking good care of our liver health is like grooming a football superstar. Always watch out of the things you are doing to it.
What Is Vitamin B-6 And What Is Its Health Benefits?
January 05, 2014 09:19 AM
Vitamin B6 is a water soluble vitamin that is part of the vitamin B complex group that consists of pyridoxal (PL), pyridoxine (PN), pyridoxal 5 phosphate, pyridoxine 5 phosphate, 4-pyridoxic acid (PA), pyridoxamine 5 phosphate, and pyridoxamine. Pyridoxine is the form that is commonly given as a vitamin B-6 supplement. Vitamin B6 is also found in most multivitamin mineral supplements.
The benefits of vitamin B-6 include:
The amount of vitamin B-6 that is needed daily by the body depends on age and sex. Men and women between the ages of 19 and 50 need 1.3mg/day, women who are 51 years and older need 1.5 mg/day, pregnant women need 1.9 mg/day, and men over 51 years need 1.7 mg/day.
Below are some of the foods that contain vitamin B6 (the amount of vitamin B6 they contain is in mg)
Fruits- per carrot juice contains 0.27 mg per 125mls, prune juice contains 0.30mg per 125 mls. and one avocado fruit contains 0.26 mg.
Grains- 30 g of wheat bran contains 0.35 mg of vitamin B6, 30 g of bran contains 0.20 mg
Meats- 75 g of cooked beef liver contain 0.76-0.78 mg, 75g of cooked beef contains 0.14-0.26 mg, 75 g of salmon or tuna contain around 0.67 mg, and other fish (trout, cod, mackerel, snapper, bluefish, and herring contain 0.30-0.39 mg.
Legumes- 0.75 of a cup of soybean contains 0.30 mg, 0.75 of a cup of chickpeas contains 0.84 mg, and 0.75 of a cup of lentils contains 0.26 mg.
The symptoms and signs of vitamin B6 deficiency include:
anemia, depression, convulsion, irritability, morning sickness, and sore tongue.
You can easily meet your daily requirements of vitamin B-6 by taking vitamin B-6 supplements. Athletes who are taking protein and amino supplements should also take vitamin B6 supplements to improve their body’s intake of the proteins and amino acids consumed.
How Does Creatine Boost Muscle Strength?
October 28, 2013 11:13 PM
How Does Creatine Boost Muscle Strength?
First of all what is Creatine? Creatine is a protein that is produced by the human body and converted to creatine phosphate and stored in muscles. The stored form can then be utilized for energy by the muscles. It is also found in meat and protein rich food products such as fish. Some clinical studies have surmised that creatine as an oral supplement enhance muscle strength and increase lean muscle bulk.
What Creatine Can Do?
Many young athletes utilize creatine supplements as part of their muscle building routines. Although there have been varied responses to these diet supplements creatine continues to thrive on the market as a sports and health vitamin. Other uses of it include lowering triglycerides in the body as well as homoCysteine both of which play a role in heart attacks and strokes. Creatine also promotes better endurance and muscle strength among patients with chronic obstructive pulmonary disease, Parkinson's disease and Muscular Dystrophy. Clinical trials are still under way.
Creatine, like all other medications and supplements may cause some adverse effects. It is important that you consult a health service provider or pharmacist before initiating the use of the supplement. The common side effects of Creatine include muscle cramps, weight gain, muscle strain, abdominal discomfort, changes in bowel movements, dizziness as well as liver and kidney dysfunction. This is due to the fact that this protein is metabolized in the liver and the kidney.
Creatine should be taken in the recommended dose. Taking more than the recommended dosage can result to severe adverse events such as Rhabdomyolysis which is the medical term for the breakdown of muscles, the components released after massive muscle cell death can damage the kidney and lead to kidney failure. The recommended dose for adults is 2g daily. Using creatine for prolonged periods may eventually lower your body's production of creatine and may lessen its effects.
When used judiciously and properly you can benefit from the positive effects of Creatine.
Can our health benefit from supplmenting choline?
November 18, 2012 11:01 AM
Choline, discovered in 1864 by the German chemist, Adolph Strecker, is an essential nutrient, usually grouped under the vitamin B family. While the human body does synthesize small amounts of choline, dietary consumption is a must in order to maintain a healthy body. Deficiency of choline can lead to a number of serious health issues including neurological problems, insomnia, accumulation of fat in the liver, damage to the kidneys and also cardiovascular disease. There are a range of important functions that choline performs in the body.
Some of the key health benefits of choline are:
Maintenance of brain health: The neurotransmitter or the messenger molecule, acetylcholine, that transmits signals from the brain to the muscles and various organs in the body such as the liver, heart, lungs etc, is synthesized using choline. Thus, it plays a very important role in memory and muscle control. Research also suggests that choline has a calming effect on the brain and helps reduce panic and anxiety attacks.
Maintenance of cell membranes: The integrity and flexibility of cell membranes depends on the presence of satisfactory amounts of choline thus making it a prerequisite for appropriate cell metabolism.
Maintenance of Liver health: Choline is responsible for preventing the accumulation of cholesterol and fat deposits in the liver hence preventing hepatosteatosis, a condition more commonly known as fatty liver.
Anti inflammatory benefits: Studies have revealed that inflammatory markers such as Interleukin-6, C-reactive protein, HomoCysteine, etc., which are associated with various illnesses such as Diabetes, Alzheimer's disease, Cardiovascular disease, Osteoporosis and also various cancers, show reduced levels if adequate amounts of choline are consumed in the diet.
Apart from those stated above there are many more health benefits of choline and hence it is very important to consume foods that are rich in this nutrient. In addition to seafood and meat, foods that have high choline content include, Dairy and poultry products like Skim milk and Egg yolk, peanut butter; Vegetables such as Cauliflower, broccoli, tomatoes, Asparagus, Green beans and Fruits like Bananas and Oranges. Soybeans, due to their high lecithin content, are also a fantastic source of choline. Seeds like flax seed, sesame seeds and grains like corn, barley and oats are also rich in choline content.
Maintenance of adequate levels of choline is imperative in order to maintain optimal health. It is therefore very important to have periodic health checkups so that any deficiencies are identified and addressed as soon as possible.
November 17, 2012 11:58 AM
Vitamin B-6 was discovered by Paul Grorgy in 1930 when doing nutritional studies. He discovered the substance was able to cure a certain skin disease when he tested it in rats. Vitamin B-6 exists in three forms namely pyridoxine, pyridoxamine and pyridoxal. These three are precursors of PLP (pyridoxal 5-phosphate). PLP plays an important role as a cofactor for most enzymes in the body.
Vitamin B-6 has many health benefits.
To begin with, it helps maintain a healthy heart. It prevents the formation of a substance, homoCysteine, which damages the lining of blood vessels resulting to the building up of plaque. This happens when the body attempts to repair the damage. It prevents the buildup, reducing chances of a myocardial infarction. It lowers blood pressure, prevents platelet aggregation and it also lowers levels of cholesterol in the body.
Vitamin B-6 from supplements or diets reduces the chances of having Parkinson's disease. In women, it strengthens their immune system and it also promotes proper hormone balance in case of any fluctuations. Vitamin B-6 deficiency exposes one to the carpal tunnel syndrome. It is a disorder that is characterized by a burning or tingling sensation and pain that is felt on the wrist or hand after being strained repetitively. It also causes numbness, loss of strength in hands/ fingers, diminished coordination and swelling. Studies have indicated that increased levels of vitamin B-6, from diets or supplements, reduce symptoms of carpal tunnel syndrome.
Toxic potential in grams per day.
Vitamin B-6 however becomes toxic if taken in excess. It does not relieve the symptoms immediately. Sometimes it takes up to six weeks before noticing any relief. Those suffering from this syndrome should take fifty milligrams of vitamin B-6 twice or thrice daily. You should never take more than two hundred milligrams of vitamin B-6unless you have been recommended to do so by a doctor.
Vitamin B-12 Energy Boost?
October 13, 2012 07:26 PM
Vitamin B-12 is among the most useful of all vitamins, because it is important to every single part of the body. In particular, it plays a vital role in producing energy, which it achieves by speeding up the body's metabolism. It also encourages red blood cells to be produced, something which is important in maintaining good circulation, as well as helping the body to maintain its levels of the iron it needs for healthy blood. This in turn gives a boost to energy.
Other tasks accomplished by vitamin B-12, which can be found either in animal-based foods or in dietary supplements, include helping nerve cells to develop. This is necessary for both the brain and the central nervous system to operate properly. Vitamin B-12 also plays a role in keeping blood sugar levels at their correct level, by balancing the levels of the chemical homo-Cysteine found in the blood. This, again, boosts energy and prevents feelings of fatigue.
The Health benefits of P-5-P
July 20, 2012 07:51 AM
P-5-P or Pyridoxal-5-phosphate
P-5-P or the most commonly called Pyridoxal-5-phosphate is known to be the most active form of the Vitamin B6. This is known to be converted from organic compounds pyridoxal, pyridoxine and pyridoxamine. The Vitamin P-5-P is a coenzyme which support several other enzymes in the body which play a important role in biosynthesis. This also makes optimum use of the vitamin B6 by improving the body metabolism and many other biological process as well. The vitamin B6 traditionally comes in the form of pyridoxine hydrochloride which the body finds difficult to synthesize in its existing state. Hence, this pyridoxine hydrochloride is processed and is formed as Pyridoxal-5-phosphate to help the body to use the vitamin B6 effectively.
There are a lot of benefits of the vitamin P-5-P
Let us have a look at some of them.
Pyridoxal-5-phosphate uses the information from the genes ad helps to produce proteins.P-5-P is also helpful in the formation of hemoglobin, histamine and neurotransmitters and is also helpful in the metabolism of amino acids, fats and glucose.Pyridoxal-5-phosphate also helps in the conversion of dopa which is a useful substance used in the treatment of Parkinson's disease. Dopa is converted to dopamine which is a neurotransmitter which is produced in the brain and is released by the hypothalamus.
The P5P is also helpful in the utilization of the food sources for the formation of energy and also helps in the easy release of glycogen which is the stored energy.P5P also converts glutamate into GABA which is gamma amino butyric acid which is again a neurotransmitter which is known to be found in the mammals. This is found in their central nervous system.The Pyridoxal-5-phosphate also helpful in the process of decarboxylation which is the conversion of histidine to histamine.
This also converts SAM-e to propylamine which is known to be a precursor of polyamines.The Vitamin P5P is also responsible to lower the homocystenie levels which are caused by the intake of high amounts of methionine.The Vitamin Pyridoxal-5-phosphate helps in the treatment of irregular heartbeat , which is a condition termed as arrhythmia.This plays a important role in the treatment of myocardial infections. This prevents the blood platelets from sticking to each other which usually causes blood clots.The enzymes produced by the Pyridoxal-5-phosphate also helps in the formation of different kinds of amino acid reactions which keeps the carbon ions stable. This process is very important in the metabolism of the cells.The P5P also helps in the metabolism of the amino acids.
Here it helps in converting methionine to Cysteine and also converts tryptophan to niacin.Pyridoxal-5-phosphate also plays a vital role in the formation of glucose. This process is known as gluconeogenesis.This also acts a important co-enzyme in the process of glycogenolysis which happens in the liver and muscles and this is known to be a reaction which occurs due to presence of glycogen.The P5P also helps in the formation of antibodies and also assists in the process of hemoglobin synthesis as well.
To keep it simpler, the vitamin P5P performs many functions which is very beneficial to the whole human body. The P5P deficiency can also happen in many individuals and even such symptoms are hard to identify. Any person suffering from the P5P deficiency will have symptoms like muscle weakness, irritability or depression. Consulting a physician and taking necessary supplements will help to overcome the P5P deficiency.
What Is Glutathione Good For?
April 14, 2012 08:03 AM
What is Glutathione?
Glutathione (GSH)is a tripeptide derived from non-proteinaceous amino acids. Contains apeptide bond between the group unusual amino of the Cysteine group and the carboxylside chain of glutamate. Glutathione, an antioxidant, helps protect cells from reactive species of oxygen such as free radicals and peroxides. Glutathione is nucleophilic at sulfuracceptors and conjugated electrophilic attack poisonous. Groups thiolare maintained in a reduced state to a concentration of about ~ 5 mM in animal cells. Indeed, glutathione reduces any link disulfideformed with in proteins cytoplasmic Cysteines by acting as a donor of electrons.In the process, glutathione is converted to its oxidized form glutathione disulfide (GSSG). Glutathione is found almost exclusively in its reduced form, since the enzyme that turns its oxidized form, glutathione reductase,is constitutively active and inducible to oxidative stress.In fact, the ratio of reduced glutathione to oxidized glutathione in cells is often used scientifically as a measure of cellular toxicity. H2O2+ GSSG + 2 ------- 2GSH H2O.
Advantages of the Glutathione
Before discussing the benefits of L-Glutathione, let's first talk a little about the nutrient. Glutathione is an antioxidant enzyme dominant which is soluble in water.It is absorbed mainly in the liver.It helps fight against free radical damage.The free radical damage is harmful relatives. Glutathione is involved in a variety of other functions in the body.
The function of Glutathione - Benefits of Glutathione
Glutathione works in DNA synthesis and repair, protein and prostaglandin synthesis, and amino acid transport.It helps in the metabolism of carcinogens and toxins.Immune system is improved through the use of Glutathione, and contributes to the prevention of cellular oxidative damage, and activation of enzymes. Glutathione also helps and maintains the functions of other antioxidants.
There is the possibility of a deficiency of glutathione. It usually occurs during aging.For example, it is seen in macular degeneration related to age, diabetes, and lung and gastrointestinal diseases. It may be the cause of pre-eclampsia, Parkinson's, AIDS and other neurodegenerative diseases.
Where to get Glutathione
Some sources of glutathione include fruits such as tomatoes, watermelon, grapefruit, oranges, peaches and cantaloupe.It is found in vegetables such as avocados, potatoes, spinach, okra, acorn squash, and asparagus.It is found in most meats as well. Other sources of vegetables such as broccoli, cabbage, Brussels sprouts, cauliflower, kale, parsley, and not only provide GSH - glutathione peroxidase, but it also stimulates the body to make more BA.Since cooking destroys much of glutathione, you will get more to eat raw or steamed vegetables for the best benefits of Glutathione.
Reduced glutathione is in a supplementation that we personally use a company called source naturals a Natural Product meeting the above requirements.The nutrient content in their signature product - Total Balance.
What Vitamins And Minerals Are For Mental Alertness?
August 29, 2011 10:33 AM
There are many vitamins and minerals which can help improve the health and functioning of the nervous system. Vitamins and minerals are significantly involved in many biological processes of the body. It influences the activities of the organs of the body including the brain. In fact, deficiencies on vitamins and minerals may result to psychological or even psychiatric symptoms in certain individuals. People with psychiatric problems are also prescribed with vitamin and mineral supplements which serve as one of its conventional treatment.
The vitamins and minerals which are good for the improvement of brain function and improvement of mental alertness are the following:
1. THIAMINE OR VITAMIN B1. Generally, insufficient amount of this enzyme may result to mild psychiatric symptoms. Studies revealed that people with inadequate amount of this vitamin has the symptoms of fearfulness, anxiety, depression, agitation and behavioral instability. This vitamin is necessary for the activity the body’s enzyme called pyruvate dehydrogenase. This enzyme is required for the conversion of pyruvate to acetyl – coenzyme A. If pyruvate is not catalyzed into acetyl – coenzyme A, the excess pyruvate in the body might be converted into lactate which can cause muscle pains and also psychiatric symptoms such as anxiety. Deficiency of this vitamin must be suspected when the person is alcoholic or malnourished.
2. RIBOFLAVIN OR VITAMIN B2. This vitamin is closely associated with major depression in relation to oxidative stress. Riboflavin is required for the metabolism of protein, fats and carbohydrates. The building blocks of these macronutrients are important for the maintenance of brain health and proper functioning of the nervous system. It can improve the energy levels and functioning of the brain, thus improving an individual’s mental alertness.
3. PYRIDOXINE OR VITAMIN B6. Studies show that low level of vitamin B6 is directly related to depression. Inside the body, pyridoxine is converted into its biochemical active form called pyridoxal phosphate which is important for mental alertness and brain functioning. Pyridoxine acts as a coenzyme involved in the synthesis of brain chemicals such as serotonin, dopamine and gamma aminobutyric acid (GABA). This vitamin is also involved in the metabolism of carbohydrates and amino acids which are essential for boosting energy levels.
4. COBALAMIN OR VITAMIN B12. Deficiency of this vitamin is closely related to decrease mental functioning. Vitamin B12 is a cofactor of the enzyme methionine synthase which is important in the conversion of homoCysteine to methionine. This is required for the production of energy in fatty acids and proteins which is important for the methylation reactions of brain chemicals.
5. VITAMIN C. This vitamin is considered to be a cofactor of the neurotransmitter dopamine and is involved in the conversion of dopamine to norepinephrine. These brain chemicals are important for the maintenance of proper mental alertness.
6. FOLATE. Decreased mental alertness and depression is a common symptom of low levels of folate in the body. This mineral is involved in the methylation and synthesis of DNA. It is important for the development of brain function and improvement of mental alertness.
7. MAGNESIUM. This mineral is involved in many reactions of the body. Individuals with decreased mental alertness are found to have low levels of magnesium in their cerebrospinal fluids.
8. ZINC. This is a mineral which is important in the catalyses of many enzyme sin the body. It is found in high amount in the brain which is important for nervous activities.
Can Vitamin B12 Boost Mental Alertness?
July 18, 2011 12:01 PM
The body needs various nutrients in order to make vital biological reactions possible. These bodily reactions are necessary for energy production, immune system enhancement and health improvement. These nutrients are classified into two, macro and micronutrients. In addition, these micronutrients are further divided into vitamins and minerals. These vitamins are needed by individuals to help the body grow normally. Vitamins can be supplied by the food we eat. However, the body can make certain vitamins such as vitamin D and K. Individuals who are in strict vegetable diet usually need vitamin B12 supplement. In this article, we will be focusing on Vitamin B 12 or also known as cyanocobalamin.
Vitamin B 12 is also a water– soluble vitamin. It is considered as essential because it is not produced by the body. Excellent sources of this vitamin include fish, shellfish, meat, milk and milk products. Vitamin B 12 is also available in supplements in combination with other vitamin B complex. Like the other B vitamins, vitamin B 12 is also necessary in maintaining healthy brain cells and in the normal production of red blood cells. Riboflavin is also a component of DNA which is the cells’ genetic material. Vitamin B 12 in the stomach combines with a substance called intrinsic factor so that it can be absorbed into the blood stream.
Vitamin B 12 boosts mental alertness because it facilitates normal formation of body cells most especially the nerve cells. Vitamin B 12 is also an important component of the myelin sheath. Myelin sheath is necessary for the proper functioning of the nerves. Myelin sheath functions by increasing the speed of the movement of the impulse. With the presence of myelin sheath, the impulse hops from one sheath to another instead of just moving continuously along the nerve fiber. This is the reason why vitamin B 12 is commonly employed for boosting mental alertness and concentration. In fact, it is also commonly employed for treatment of memory loss and Alzheimer’s disease.
Vitamin B 12 can also help lower the risk of cardiovascular diseases by decreasing the concentration of homoCysteine in the blood stream. Studies show that high levels of homoCysteine can greatly lead to atherosclerosis which is the narrowing of arterial walls. It can also increase the tendency of abnormal blood clotting thus increasing the risk of clotting – related disorders. These factors can precipitate heart attacks and cerebrovascular accidents or commonly known as stroke.
Another function of vitamin B 12 is its involvement with energy metabolism in every cell of the body. Therefore, vitamin B 12 is not only good for enhancing mental alertness but also increasing energy levels. It is also required by the body so that other nutrients from the diet can be absorbed and readily utilized by the cells.
Vitamin B 12 is relatively safe. It usually comes in combination with other B vitamins in the form of tablets, capsules, or liquid which can be bought over –the – counter.
Boost Energy, Improve circulation Heart Disease, And More with Methycobalamin (B12)
June 16, 2011 11:45 AM
Methylcobalamin is an organic compound that displays vitamin B12 activities inside the human body. It is one of the active forms of vitamin B12, and as such believed to be the most bioavailable of all vitamin B12 supplements. In fact, all other forms of vitamin B-12 in the market are converted into methylcobalamin when ingested. Its high absorption rate enables it to produce visible health benefits.
Influences Energy Production
Vitamin B12 is an indispensable component of many cellular activities. It is quite pervasive at the cellular level, inasmuch as it is directly involved in chemical reactions that lead to the production of adenosine triphosphate(ATP), the primary source of energy that fuels all metabolic processes within cells.
In particular, methylcobalamin participates in DNA synthesis, allowing each cell to effectively perform its physiological roles. Healthy levels of methylcobalamin protect the cells from DNA damage, and contribute to the rate of metabolism. Vitamin B12 deficiency seriously affects energy production.
Promotes Circulatory Health
Studies on anemia led to the discovery of vitamin B12. The causes for anemia were uncovered at the turn of the 20th century. High consumptions of liver appeared to cure anemia as liver are high in the dietary mineral iron. It was also later identified that vitamin B12 also cure one specific case of anemia.
Pernicious anemia is one of the many types of megaloblastic anemia, in which red blood cells appear large but immature. This results from a deficiency in vitamin B12. Methylcobalamin supplements have shown the best recovery rate for this type of anemia, promoting circulatory health in the process. The presence of methylcobalamin in the blood powers DNA synthesis and nourishes red blood cells.
Prevents Heart Disease
Methylcobalamin is particularly good for the heart and the blood vessels. Its presence in the bloodstream influences the levels of organic compounds, such as homoCysteine, which are implicated in the death of myocardial cells and the formation of risk factors of cardiovascular diseases. The same endogenous compounds are incriminated in life-threatening conditions such as heart attacks.
Elevated levels of homoCysteine in the blood raise the levels of asymmetric dimethylarginine, or ADMA, which directly cause cardiovascular disease. Regular intake of methylcobalamin has been observed to lower serum levels of homoCysteine, which in turn lower ADMA concentrations in the bloodstream.
Improves Neuropathic Disorders
Neuropathy refers to damage to nerve cells to the extent of producing symptoms, such as muscle weakness, impaired reflexes, gait abnormalities, muscle twitch, tingling sensation, difficulty swallowing, speech impairment, urinary incontinence, and erectile dysfunction, among others.
Vitamin B12 is one of the many causes of peripheral neuropathy. Not surprisingly, supplementation of methylcobalamin significantly improves symptoms in very little time. Methylcobalamin has also shown encouraging results as an adjunct treatment for diabetic neuropathy. As a result, it also corrects the symptoms tied to neuropathic disorders, notably reflex impairment and muscle weakness.
Pick Up some Methylcobalamin (b-12) today and feel the difference!
How Does Taurine Help the Brain?
May 13, 2011 01:09 PM
Taurine is an amino acid often added to energy drinks. There have been several theories on how taurine affects brain chemicals and improve cognitive function. For many years, it has been compared to caffeine due to its effects on the human brain that appear to enhance mood. Its exact mechanisms of action remain a mystery to the scientific community, but recent studies are believed to be closing in.
It has long been known that taurine crosses the blood brain barrier, allowing it to exert some effects on several neurotransmitters found in the central nervous system. It has been tied to the alleviation of many mental illnesses, such as epilepsy, post traumatic stress disorder, clinical depression, bipolar disorder, and anxiety, making it the subject of a number of studies in the past few years.
Rebalances Brain Chemicals
It has been postulated that taurine influences the activities of neurotransmitters in the brain, but only recently has brain scientists been able to actually track its activities in the brain. A team of researchers at Cornell University managed to find a site for the neurological activity of taurine, with initial results pointing to its relationship with gamma the neurotransmitter aminobutyric acid, or GABA. The researchers do not discount the possibility that taurine may even have a receptor of its own.
Whether taurine interacts with brain chemicals is no longer debatable as it creates homeostasis in the central nervous system. It acts on receptors that the researchers discovered to be the same receptors present in GABAergic mechanisms. That being said, scientists remain inconclusive as to how its interaction with GABA receptors provides energy-boosting benefits as it is marketed in the food and drug industries.
Prevents Neuron Damage
The scientific community is convinced that taurine has neuroprotective properties. High levels of taurine in the brain have been observed to protect brain tissues from cerebral ischemia. Taurine has been linked to many metabolic pathways that are known to promote neurological health, such as the activation of glycine receptors and the regulation of enzymes called Cysteine-dependent aspartate-directed proteases.
In addition, taurine serves as antioxidants that protect nerve cells from cellular damage brought on by oxidative stress. The presence of taurine within cells reduces damage from calcium excesses and increases mitochondrial events. For decades, supplementation of taurine has benefited sufferers of brain ischemia, epileptic seizures, panic attacks, anxiety symptoms, and even alcohol withdrawal.
Enhances Cognitive Function
Taurine has already been associated with physiological functions the hypothalamus controls, such as sleep-wake cycle and responses to fatigue. In several laboratory studies, administrations of taurine by way of intraperitoneal injection have successfully induced social interaction in animal subjects. It is one of the amino acids that affect cognitive development, especially in children. While it is one of the most abundant amino acids in the brain, it is depleted as we age, making supplementation a good option.
Protect your brain with Taurine by taking it daily!
I Am a Vegetarian, Should I be Taking a B-12 Vitamin Supplement?
February 28, 2011 12:52 PM
Vitamin B12 And Your Health
Vegetarians are especially in risk of deficiency in vitamin B12 in that there are no plant sources known to contain significant levels of this essential nutrient. While the body is capable of storing this vitamin in the liver enough to meet the daily needs for several years, those who are following a strict vegan diet for long periods of time are in danger of developing many different medical conditions, including heart diseases, neural impairment, and anemia. Most vegetarians do not realize the seriousness of vitamin B12 deficiency as its symptoms often materialize in later life when the damage may no longer be reversible. Fortunately, total vegetarians do have options without renouncing their beliefs, inasmuch as Vitamin B12 supplements have shown to meet the nutritional needs of the body.
Removes Neurological Problems
One of the mishaps of long-term vegetarianism is the incidence of neural tube defects in babies, inasmuch as developments in the nervous system in the first periods of pregnancy is compromised in women who have very low levels of vitamin B12 does not have enough even with excessive quantities of folate. Nerve cells in particular are very sensitive to the absence of this vitamin. Many vegetarians are under the impression that plants contain every nutrient that the human body needs, which is completely misleading. Only bacteria have the enzymes required to manufacture vitamin B12, and these bacteria are present in the gut of animals. The good news is that vitamin B12 supplements that are available in the market today are good source of the active forms of this vitamin, and has stood the test of time in reversing the deficiencies brought on by malnutrition.
Prevents Cardiovascular Diseases
High levels of homoCysteine are another consequence of low levels of vitamin B12 in the blood. A rise in homoCysteine concentrations in the blood serum is a very important risk factor for cardiovascular diseases, and may come to an extent that is no longer reversible. Atherosclerosis and coronary heart disease are among the disorders tied to elevated homoCysteine in the bloodstream, the reason why supplementation vitamin B12 has been used to treat certain medical conditions involving the heart and the blood vessels. The availability of vitamin B12 is in fact inversely proportional to the quantities of homoCysteine produced by the body, and supplementation starting in the early years has shown to remove all the dangers related to homoCysteine.
Supplies the Body with Energy
It is a known fact that vitamin B12 supplements affect chemical processes implicated in the production of energy. They are now widely accepted to be good for individuals involved in endurance sports and for the regular guy who usually relies on caffeine. Vitamin B12 stimulates the conversion of fatty acids into cellular energy, and influences the production of red blood cells, producing the vitality we need minus the jittery effects of coffee. For athletes, it does not only provide energy but also ensures cardiovascular health as homoCysteine levels are directly proportional to exercise duration.
If you do not eat much red meat and do not take a supplement, you might be deficient or boarder line at best in vitamin B12. Taking a supplement is the easy way to boost B12 and improve your health.
Taurine - Essential or Non-Essential Amino Acid - You Decide?
February 17, 2011 10:56 AM
Amino Acid Taurine Is Essential For More Than You Think
Taurine is an organic compound with acidic properties, which is synthesized in the pancreas in adults, but an essential amino acid in infants. Many neutraceutical products for infants are fortified with taurine, inasmuch as some newborns do not have the enzymes required to synthesize taurine. Taurine deficiency in adults results from deficiencies in other organic compounds, notably methionine and Cysteine, which are its immediate precursors within the body.
Helps in Brain Development
It has long been postulated that taurine plays an important role in the human brain, especially in infants, protecting the nerve cells from possible neonatal damages. Taurine continues to affect the nervous system as we age, acting on gamma-aminobutyric acid, or GABA, and consequently enhances inhibitory synaptic transmissions. In addition, taurine is alleged to stimulate continuous activation of synapses characteristic of long-term potentiation, which memory and learning ability stem from.
Stabilizes Glucose Levels
Taurine is a powerful inhibitor of glycation, a process by which sugar molecules attach themselves to other biomolecules without the aid of enzymes, and thus subsequently impair the functions of these biomolecules. This process may take place inside or outside the body, but the substances that result from this process, which are referred to as advanced glycation end-products or AGEs, contribute to the formation of a number of major disorders in later life such as cardiovascular diseases, Alzheimer’s disease, age-related deafness and blindness, and cancer. Taurine keeps the cells from taking up AGEs from the blood, which is slowly excreted in the urine.
Regulates Adipose Tissues
It has also been observed that dietary taurine influences the metabolic pathways that give rise to the formation of adipose tissues, the fat reserves of the human body. These fat depot appear anywhere in the body, but are commonly tied to the subcutaneous fats, those that we see on the belly, chest, arms, and thighs. Moreover, body fat percentage has been an indicator of obesity, which is central to the use of taurine in regulating adipose tissues.
Influences Lipid Absorption
Taurine is a major component of bile, the fluid produced by the liver, stored in the gallbladder, and secreted in the small intestines to aid in the digestion of triglycerides, cholesterol, and other lipids. Also, several studies point to the effect of taurine on the binding of proteins to lipids to form lipoproteins, compounds that have been notoriously labeled as bad cholesterol. Not surprisingly, taurine has been suggested to maintain healthy levels of blood cholesterol and prevent cardiovascular diseases.
Fights Oxidative Stress
Sodas have become a part of our daily diet today, but little did we know that they are risk factors for oxidative stress, the continued peroxidation of cellular structures. Fructose in sodas and other sweetened beverages is the most dangerous of all sugars, inasmuch as it releases by-products called AGEs, which are highly reactive to oxidation. AGEs do not get excreted right away and are instead absorbed by cells, leading to irreversible damages to neuronal and vascular tissues in later life. Intake of taurine removes this problem.
Have you had your Taurine Today?
Can N-Acetyl Cysteine Boost Liver Health And Function?
February 10, 2011 12:31 PM
N-Acetyl Cysteine (NAC) And The Liver
N-Acetyl Cysteine or NAC is an antidote for poisonous effects of paracetamol overdose. It targets the cells in the liver, raising their capacity to deal with harmful metabolites. There are a number of researches well underway that scrutinizes a variety of medical conditions for which this compound could be of use. It is a known precursor of antioxidants and in itself a scavenger of peroxides and free radicals.
Hepatocytes are the cells that take on most of the functions of the liver and account for more than 70 per cent of the liver’s total mass. These cells are responsible for the presystematic metabolism of drugs, also known as the first-pass effect, rendering most drugs innocuous before they are released into the bloodstream. The total amounts of bioactive substances that are distributed to the rest of the body are also largely regulated by hepatocytes, notably carbohydrates. In addition, they are involved in the biosynthesis of protein, cholesterol, phospholipids, and bile salts as well as the functional reserves for protein.
Hepatocytes and Toxins
Certain drugs produce toxins when broken down by hepatocytes. A classic example is the metabolism of ethanol into acetaldehyde, which is a toxic compound, a probable carcinogen, and an air pollutant emitted by combustion of cars and tobacco smoking. While hepatocytes are known for their detoxifying responses to toxic substances entering the body, the metabolism of toxins actually takes up a great deal of time, resulting in certain toxins getting released into the bloodstream prior to first-pass effect.
That being said, continued exposure to toxins wears down hepatocytes, and high concentrations of what we refer to as poisons is certain to bring damage to the liver. This is what happens during overdose of paracetamol, or acetaminophen. In an effort to metabolized excessive amounts of the drug, the liver cells produce by-products that are essentially poisons, which under normal circumstances can be contained well.
NAC and Glutathione Production
The major antioxidant synthesized by the human body called glutathione comes to the liver’s defense when toxic by-products are produced. Hepatocytes in particular are so dependent on glutathione in the quenching of toxins that it has been observed that any challenge to the manufacture of this endogenous antioxidant will ultimately result in liver failure.
Glutathione is released by hepatocytes in large amounts especially during the metabolism of alcohol and drugs, but during overdose the ravaging activities of ethanol or drug metabolites overwhelm the detoxifying effects of antioxidant reserves in the body. Simply put, the defense mechanisms in the employ of the body have limits. NAC resolves this problem.
The presence of NAC in the body augments the liver’s ability to produce the needed amounts of glutathione to effectively counter the harmful properties of invasive substances. In fact, the liver completely recuperates in a matter of weeks even after life-threatening conditions given that NAC is introduced in the human body in time to avoid subsequent damages to other vital organs. Indeed its application has proven to save lives in fatal cases of paracetamol poisoning.
N-Acetyl Cysteine is available at your local or internet vitamin store in capsule or tablet forms. Always choose name brands like Source Naturals to ensure quality and purity of the product you buy for better liver health.
Have you had your NAC today?
How to detoxify from heavy metal aluminum toxitity
November 09, 2010 06:04 PM
Although aluminum is not a heavy metal, it can be toxic if present in excessive amounts or small amounts if it is deposited in the brain. Many of the symptoms of aluminum toxicity are similar to those of Alzheimer’s disease and osteoporosis. Aluminum toxicity can often lead to colic, rickets, gastrointestinal disturbances, poor calcium metabolism, extreme nervousness, anemia, headaches, decreased liver and kidney function, forgetfulness, speech disturbances, memory loss, softening of the bones, and weak, aching muscles. Since aluminum is excreted through the kidneys, toxic amounts of aluminum can often impair kidney function.
When aluminum salts accumulate in the brain, seizures and reduced mental function can often result. In order to reach the brain, aluminum must pass the blood-brain barrier, which is an elaborate structure that filters the blood before it reaches the vital organ. Although elemental aluminum does not ordinarily pass through this barrier, certain aluminum compounds, such as aluminum fluoride, will. Many municipal water supplies are treated with aluminum sulfate and fluoride. These two chemicals readily combine with each other in the blood and are poorly excreted in the urine. The absorption of high levels of aluminum and silicon in the intestines can result in the formation of compounds that accumulate in the cerebral cortex and prevent nerve impulses from being carried to and from the brain in the proper manner. This situation can be aggravated by a chronic calcium deficiency.
People who have spent their career in aluminum smelting plants for long periods have been known to experience dizziness, impaired coordination, and a loss of balance and energy. When aluminum accumulates in the brain, the above symptoms are often caused. Perhaps the most alarming thing to note it that there is evidence to suggest that long-term accumulation of aluminum in the brain may contribute to the development of Alzheimer’s disease. It has been estimated that an ordinary person ingests about 3 and 10 milligrams of aluminum a day. Aluminum, being the most abundant metallic element in the earth’s crust, is primarily absorbed in the body through the digestive tract, but can also be absorbed through the lungs and skin. Additionally, aluminum can be absorbed by and accumulate in the body tissues. Since aluminum permeates our air, water, and soil, it can be found naturally in varying amounts in almost all food and water. Aluminum is also used to make cookware, cooking utensils, and foil, along with being present in many other everyday products including over-the-counter painkillers, anti-inflammatories, douche preparations, antacids, baking powder, food processing, antiperspirants, toothpaste, dental amalgams, bleached flour, grated cheese, table salt, beer, and municipal water supplies.
The following nutrients are very helpful when dealing with aluminum toxicity: apple pectin, calcium, magnesium, coenzyme A, garlic, kelp, lecithin capsules or granules, l-glutathione, a multivitamin and mineral complex, SAMe, vitamin B complex, N-Acetyl Cysteine, and vitamin E. Additionally, the following herbs are great for blocking damage to the body from toxic heavy metals and radiation when taken regularly: burdock root, Echinacea, ginseng, ginkgo biloba, and fiber. Other recommendations to help prevent aluminum toxicity include maintaining a diet that is high in fiber and includes apple pectin; using only stainless steel, glass, or iron cookware, with stainless steel being the best; and being aware of the products that contain aluminum by reading labels and avoiding those that contain aluminum. Sulfur container foods like N-Acetyl Cysteine can help find up heavy metals and eliminate them from the body. If you suspect you have heavy metal toxicity, consult your health care provider immediately.
Glutathion, Antioxidants, And The Body
July 14, 2010 02:41 PM
Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, Cysteine, and glycine. Due to the chemical nature of sulphur-containing Cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges.
Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis.
A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids.
The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell.
Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion.
Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well.
Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.
Build Healthy Bones With A Good Bone Builder Supplement
May 22, 2010 12:17 PM
Since bones are living tissue, healthy bones need at least 24 bone-building materials in order to be at their best. These materials include both trace elements and protein. The most important minerals to bone health are calcium, magnesium, phosphorus, and potassium. The balance between these minerals is just as important as well. Strong bones need a lot of calcium, but calcium supplementation must include the presence of magnesium, as it increases the retention of calcium within the bone. Phosphorus is another important component in bone formation, as it must be in proper balance with calcium. If you take too much of it, which can be gained through soft-drink consumption or high protein intake, it will suck the calcium out of the bone, therefore, weakening the bone’s integrity. Vitamins D and K are also essential for increased calcium deposition.
Silicon, boron, and zinc are also required in order to strengthen the bone’s mineral matrix. Vitamin C stimulates the formation of the collagen matrix, which is an extremely important protein component that creates a structure for calcium crystallization. Silicon increases the bone-mineral density. Additionally, it seems to have a role in the prevention and treatment of osteoporosis. Silicon deposition is found in areas of the body that experience active bone growth. Because of this, it is suggested that this mineral may be involved in the growth of bone crystals as well as the process of bone mineralization. Zinc is also important for the proper action of vitamin D, as its status plays a huge role in bone health. When an increase in zinc excretion takes place, accelerated depletion of bone-mineral content also results. This situation is very common among osteoporosis sufferers. Diets that are low in zinc have also been shown to slow adolescent bone growth as well.
Lastly, vitamins B6, B12, and folic acid are necessary for reducing mineral loss as they modulate blood homoCysteine levels. Vitamin B6 is a water-soluble vitamin used in the metabolism of amino acids. Vitamin B12 is one of eight B vitamins which is crucial for the normal functioning of the brain and nervous system, as well as the formation of blood. It is normally involved in the metabolism of every cell of the body. It affects DNA synthesis and regulation as well as fatty acid synthesis and energy production. Folic acid is a form of the water-soluble vitamin B9. It occurs naturally in food and can also be taken as a supplement.
The scientific evidence that has been found has supported the need for long-term supplementation with several key nutrients in order to maintain bone health. This is especially true for those women who are in their peri- and post-menopause years. Supplementation with vitamins D, K, C, B6, B12, folic acid, as well as the minerals boron, calcium, magnesium, silicon, and zinc at levels that are declared to be suitable for optimal nutrition health by nutritional authorities is an important component of product-rating criteria. Researchers question whether each product contains vitamin D, vitamin K, vitamin C, vitamin B6, vitamin B12, folic acid, boron, calcium, magnesium, silicon, and zinc at potencies that are up to 100% of the potencies for these nutrients that are stated in the Blended Standard.
Look to your local or internet vitamin store for bone building formulas that contain all these essential vitamins to help the body support a healthy bone structure. Remember to always choose name brands like Eithical nutrients and Solaray to ensure you buy a high quality complete bone building supplement.
Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it
February 25, 2010 09:47 AM
Sunburn is the result of excessive exposure to the sun’s ultraviolet (UV) rays. The amount of exposure that is required to cause a burn is unique to each individual, the geographical location, the time, and the atmospheric conditions. There are two types of ultraviolet rays, which are designated as ultraviolet-A (UVA) and ultraviolet-B (UVB). Both types of ultraviolet rays are dangerous. UVB rays attack the skin’s outer layers, while UVA rays attack the underlying layers of the skin.
The majority of sunburns are first-degree burns that cause the skin to become red, warm, and tender to the touch. Depending on the severity of the burn and the individual’s skin type, the burn may subsequently “cool” into a suntan or thin layers of skin may peel off. More serious sunburn can be categorized as a second-degree burn. A second-degree burn consists of extreme reddening, swelling, pain, and even blisters. This is a sign that the burn has gone deeper than just the surface layer of the skin and has caused damage and the release of fluids from cells in the lower layers of the skin. The result of this is eruptions and breaks in the skin where bacteria and other infectious organisms can enter. In the most severe cases, a burn can be accompanied by chills, fever, nausea, and/or delirium. These types of sunburns are extremely painful and are extremely dangerous for children. Sunburn can often be accompanied by dehydration.
Those people who are fair-skinned are more prone to sunburn than those darker-skinned individuals. However, no matter what your skin color, you will burn if you get enough exposure. Symptoms do not always appear while you are in the sun, as they may begin from one hour to twenty-four hours after sun exposure and they usually reach their peak in two to three days.
The effects of sun exposure are becoming an increasing concern today due to the decline in the earth’s ozone layer. The ozone layer is responsible for screening out the most harmful ultraviolet rays, but it is becoming increasingly thinner all over the world. Holes that fluctuate in size have even developed in various places. Additionally, the incidence of skin cancer is growing at an alarming rate. It has been found that having two or more bad episodes of sunburn as a child can make you much more likely to develop skin cancer as an adult.
The following nutrients are recommended for prevention and treatment of sunburn: coenzyme Q10, colloidal silver, DMB, a free-form amino acid complex, L-Cysteine, a multivitamin and mineral complex, potassium, Pycnogenol, vitamin A with mixed carotenoids, vitamin C with bioflavonoids, an all-purpose bactericide spray, calcium, magnesium, essential fatty acids, silica, a vitamin B complex, vitamin E oil, and zinc.
Additionally, the following herbs may be beneficial in treating sunburn. Aloe vera gel has been noted to be remarkably effective in treating any kind of burn. It is responsible for relieving discomfort, speeding healing, and also helping to moisturize the skin and relieve dryness. A salve of calendula flowers and St. John’s wort can act as painkiller for burns and promote healing of skin wounds because these herbs have antiseptic properties.
Also, Lavender oil or chamomile oil used in a herbal bath can help to minimize the stinging and pain of sunburn. Comfrey and gotu kola tea can be made it to a compress for the affected area. Horsetail is good for tissue repair, while tea tree oil can help to heal sunburn and other skin irritation. Apple cider vinegar diluted with water is a great wash for sunburned areas.
To prevent sunburns, apply sunblock on any exposed skin before going out side to prevent skin damage before it starts.
Oil Skin Treatment
February 12, 2010 12:31 PM
Oily skin is the result of the sebaceous glands, which are the oil-secreting glands, produce more oil than is needed for proper lubrication of the skin. The excess oil is responsible for clogging pores and causing blemishes. Oily skin is most likely a result of heredity. However, it is known to be affected by factors such as diet, hormone levels, pregnancy, birth control pills, and the cosmetics that you use. Humidity and hot weather stimulate the sebaceous glands to produce more oil. However, it can occur at any age. A lot of people have skin that is oily only in certain areas and dry or normal in others. This condition is known as combination skin. Generally, the forehead, nose, chin, and upper back tend to be the areas that are more oily than other areas.
Oily skin does have some positive aspects. This type of skin is slow to develop age spots and discoloration, fine lines, and wrinkles. Often, it doesn’t freckle or turn red in the sun. It actually tans evenly and beautifully. On the negative side, oily skin is extremely prone to breakouts, even past adolescence. Oily skin also has a chronically shiny appearance, an oily or greasy feeling, and enlarged pores. The following nutrients are recommended for the prevention and maintenance of oily skin. The dosages recommended are for adults unless otherwise specified. For children between the ages of twelve and seventeen, the dosages should be reduced to three-quarters the recommended amount.
Flaxseed oil capsule or liquid in dosages of 1,000 mg daily or 1 tsp daily is helpful in supplying needed essential fatty acids. This nutrient is a good healer for most skin disorders. 25,000 IU of vitamin A for three months is necessary for healing and construction of new skin tissue. Vitamin B complex should be used as directed on the label as B vitamins are important for healthy skin tone. 1,000 to 1,500 mg of kelp should be taken daily. This nutrient is responsible for supplying balanced minerals that are needed for good skin tone.
Vitamin E should be taken in dosages of 200 IU daily or 400 IU every other day to protect against free radicals. 50 mg of zinc should be taken daily for tissue repair. This nutrient also enhances immune response. Grape seed extract should be taken as directed on the label, as it is a powerful antioxidant that protects skin cells. 500 mg of L-Cysteine should be taken on an empty stomach, as it contains sulfur which is needed for healthy skin. 1 tsp of lecithin granules should be taken three times daily before meals. This nutrient is needed for better absorption of the essential fatty acids. SOD should be taken as directed on the label. It acts as a free radical destroyer. Tretinoin should be used as prescribed by a physician. This nutrient acts as a gradual chemical peel, unclogs pores, and speeds up sloughing off of top layers of skin. It helps to expose new, fresh skin.
Additionally, the following herbs may be beneficial: aloe vera, burdock root, chamomile, horsetail, oat straw, thyme, lavender, lemongrass, licorice root, rosebuds, and witch hazel. If you have a oily skin, washing the affected area two or three times daily will help keep the skin oil free and reduce acne along with a healthy diet low in sugar and vitamin supplements.
May 08, 2009 10:00 AM
L-Cysteine is what is known as a non-essential amino acid, meaning that it can be biosynthesized by the body and hence not an essential part of your diet. Due to its possessing a thiol side chain, it is termed a hydrophilic amino acid with an affinity for aqueous systems. Because of this it is relatively highly reactive, and is therefore an important component of a large number of enzymes and proteins.
Although, after all, it is not an essential amino acid, deficiencies can occur in the young and in the old, and also in those suffering certain metabolic diseases. Dietary sources include high-protein foods such as chicken, turkey, pork, dairy products and vegetables such as cereals, broccoli, garlic and onions.
The biochemistry of this amino acid begins with another amino acid known as serine, and also methionine. The latter is fist converted to homoCysteine, which is then combined with serine to form cystathionine. This is then converted into Cysteine and alpha- ketobutyrate. The thiol group is highly reactive and gives Cysteine its biological properties.
L-Cysteine possesses strong antioxidant properties due to the thiol group which easily undergoes redox reactions. However, it is for its detoxification effect on the body that the amino acid is mainly taken as a supplement. It is, therefore, these properties that we shall discuss first.
Cysteine can reduce the toxic effects of alcohol, such as a hangover or the more serious liver damage. The by-product of alcohol metabolism that does most damage and is responsible for the majority of the negative after-effects of excessive alcohol consumption is acetaldehyde. L-Cysteine converts acetaldehyde into the more acceptable acetic acid, and so prevents the aldehyde from having too much of a negative effect on your health and well-being. However, the results obtained from such studies have been from animals only, and the therapeutic effects of Cysteine have not yet been tested on humans.
What has been tested and is known is that L-Cysteine is effective in the detoxification of heavy metals in the body. A common source of heavy metal toxicity is mercury from amalgam fillings in the teeth. Although the Environmental Protection Agency (EPA) declared in 1989 that dental amalgams are a hazardous substance under the Superfund law, many people still have them in their mouths.
The thiol group and L-Cysteine has a high affinity for mercury and other heavy metals, as previously stated, and a supplement can be used to remove from the body any mercury leached from mercury-based tooth fillings. It can also be used to bind to copper, lead and cadmium. Lead and cadmium are particularly toxic to the human body, and even though lead is no longer used in plumbing or paints, and cadmium in toys or paints, there are still many sources of these two heavy metals available that can lead to human toxification.
An L-Cysteine supplement can be used to remove these heavy metals from the body. Any proteins containing Cysteine will tightly bind heavy metals such as lead, cadmium, molybdenum, cobalt and mercury, and allow them to be excreted by the body in the usual fashion. This direct involvement in heavy metal detoxification is a very useful property of this amino acid.
Another detoxification application of L-Cysteine is in direct involvement in protecting cellular glutathione levels, and also the prevention of the death of liver cells by acetaminophen poisoning. The latter is of particular interest to many people since acetaminophen is better known as paracetamol, and since this is a freely available over-the-counter drug, overdoses are not unknown. The result of an overdose is the necrosis of liver cells, with eventual liver failure and death.
The treatment of choice is N-acetylCysteine. If used within 10 hours of the overdose it is extremely effective, and even from 16 to 24 hours it is better than other controls. It is believed that the acetylCysteine liberates Cysteine which, when available to the liver, enables the biosynthesis of glutathione. Glutathione can then maintain the production of the fifth metabolite required for the specific detoxification of the paracetamol/acetaminophen.
L-Cysteine is also an essential component in the biosynthesis of coenzyme A, an enzyme essential for the production of energy from fats and carbohydrates. It is also a very important component of hair, from which it is commercially produced. Without an adequate intake of L-Cysteine the growth of healthy hair would not be possible.
There are several supplemental uses of L-Cysteine including the treatment of bronchial conditions for which the amino acid can help to liquefy and clear mucus from the airways and lungs. It is also used to protect against side effects of chemotherapy treatment of cancers and for medical treatments for excessive exposure to radiation.
However, there are certain situations in which L-Cysteine should be avoided when at all possible. Diabetics should not use it, and neither should those suffering from cystinuria, whereby large quantities of amino acids, including cystine, are excreted in their urine. L-cystine, incidentally, is formed by oxidation of L-Cysteine.
Paradoxically the amino acid is one of the several hundred additives made to tobacco by the cigarette companies. Although, as with the majority of tobacco additives, its purpose is unknown there are two possible reasons for its inclusion. L-Cysteine is a known expectorant, so it could be added to promote the expectoration of mucus in the lungs which is promoted by smoking, and it also increases the production off the antioxidant glutathione that is depleted in smokers.
There are several other non-medical uses for the amino acid, but it is for is its detoxification properties that it is most used as a supplement. However, because it is largely derived from human hair or duck feathers, it may not be classed as kosher or halal in spite of many claims made to that effect, though the more expensive source of microbial fermentation from corn sugar can be.
The substance is recognized as safe by the FDA, and must be labeled as L-Cysteine when it is present in a preparation intended for its therapeutic effects. Keep in mind however, that it should be avoided by diabetics.
May 02, 2009 11:41 AM
Methionine is an essential amino acid, meaning that it is not synthesized by the body, and so has to be taken as part of your diet. It also contains sulfur, one of two sulfur-containing amino acids that can form proteins, the other being Cysteine. It is a precursor for taurine, which is an aminosulphonic acid, and not strictly an amino acid, which together with Cysteine supports the health of your cardiovascular system and helps to eliminate toxins from the body.
Maintenance of Cell Membranes
It is also an important intermediary in the maintenance of cell membranes. Phospholipids are fat-soluble components of the cell membrane, phosphatidylcholine being a very important example. Also known as lecithin, this substance is derived from choline, itself biosynthesized in a chemical pathway involving S-adenosylmethionine.
This substance is made in the body from ATP (adenosine triphosphate) and methionine with the help of the enzyme methionine adensosyltransferase. Known as SAM (or SAM-e), S-adenosylmethionine employs a number of metabolic pathways in its reaction, though generally aminopropylation, transmethylation and transsulfuration. These add aminopropyl, sulfo and methyl groups to a number of substances, the most common being the methylation of proteins, nucleic acids and lipids.
Phosphatidylcholine is produced by the enzyme-catalyzed sequential methylation of phosphatidylethanolamine, SAM donating the methyl groups. The maintenance of the integrity of the cellular membrane by phosphatidylcholine is critical to all of the basic processes in human biology, including communication between cells, flow of information and bioenergetics.
A by-product of this reaction is homoCysteine, formed in the liver from the S-adenosylhomoCysteine that SAM is changed to after donating methyl groups. Excess homoCysteine in the blood can create the risk of myocardial infarction and cardiovascular disease. SAM is also of use in the treatment of depression and of arthritis.
Creatine is a substance well known to athletes as being useful in provide short-term energy for high-intensity training. Although available in the diet, about 50% creatine used by the body is biosynthesized from methionine and two other amino acids, glycine and arginine. It allows a burst of energy lasting about 10 seconds, carried out without the use of glycogen reserves or fatty tissue.
Glycine and arginine combine to release ornithine as a by-product, and form guanidino acetate. SAM donates a methyl group to the latter to form creatine, about 95% of which is then stored in the skeletal muscle tissue. The stored creatine phosphate has the effect of allowing the muscle cells to hold more water, which also enables an enhanced level of protein synthesis, and hence an increase in muscle bulk, which also results from the increased blood flow resulting from the short-term high-intensity exercise that creatine allows.
Creatine can also increase the levels of MRF4 (myogenic transcription factor), resulting in an increasing in the myonuclei provided by satellite cells to damaged muscle tissue, that not only repair damaged muscle fibers, but also increase their ability to grow.
Detoxification of the Liver
Substances that help the liver to process fats, or lipids, are known as lipotropic, and the important lipotropics in human biochemistry are imositol, betaine, choline and methionine. They prevent fat from accumulating in the liver, and methionine is also useful in its effect of glutathione. This is a substance that helps the liver to neutralize toxins, such as excessive doses of acetaminophen, and its supplies are regulated by methionine.
Methionine and Autism
Research into autism is closely studying the Methionine/Glutathione Transsulfuration Pathway. This pathway is a very important biochemical means of detoxification, whereby toxins are methylated and then excreted. This pathway seems to be disrupted in autistic individuals.
Not only that, but disruption can lead to oxidative stress which results in many health problems. An example of this is the build-up of the oxidant homoCysteine when there is insufficient Vitamin B6 to convert it into Cysteine. This has been discussed previously, and is discussed again below.
Although research is in its infancy, it appears that AIDS sufferers also have decreased levels of methionine in their blood. It is believed that the process of AIDS could be linked to this, particularly the dementia that can occur as a result of the deterioration of the nervous system.
It is also hoped that it can help with some symptoms of Parkinson's disease, and pancreatitis. Initial research into this use of methionine has been very promising, as are studies into its use for urinary tract infections. It appears to operate like cranberry in this respect, preventing bacteria from attaching to the cell walls and multiplying in the urinary tract.
Methionine is believed to be essential for the formation of collagen, and for healthy pliable skin, hair, nails and other forms of connective tissue. For this reason it is often used as a supplement for the treatment of arthritis, although an excess should be avoided for reasons discussed above. S-Adenosylmethionine generates homoCysteine during the biosynthesis of phosphatidylcholine, and this can cause cardiovascular problems.
So stick to the recommended doses when you use methionine as a supplement. Used properly, and according to instructions, it offers many health benefits, and can also be used to bulk up your muscle tissue and give increased energy when you need it most.
Dietary sources include fish, eggs, lentils, onions, garlic, meat, seeds, spinach and yoghurt. A good supplement would be from 800mg - 1000mg per day, and is best taken along with a B vitamin complex, or at least folic acid and vitamins B6 and B12, in order to prevent the increased generation of homoCysteine.
Methionine also promotes the excretion of estrogen, so is a possible supplement for women on oral contraceptives that lower the production of this hormone. The elderly might also benefit from a supplement although, if taken for any specific condition, your health professional should be consulted first, as they should be for any supplement.
Nevertheless, methionine is a very useful supplement, and can be taken to prevent a large number of conditions. Research is continuing on its effect on AIDS patients, and Parkinson's, and it is hopeful that it will one day be recommended to help people suffering from these conditions.
Protect The Liver with Glutathione And Cysteine
April 23, 2009 01:54 PM
The tripeptide L-glutathione is synthesized in the body from L. glutamic acid, L-Cysteine and glycine, a reaction that can occur in any cell of the body although it is essential that it also occurs in the liver. Should glutathione concentrations drop, they can be increased by supplementing with Cysteine or any other of the three amino acids that are used in the biosynthesis of this important if substance
The tripeptide exists in two forms: the reduced form (GSH) which contains a sulfhydryl (SH) functional group attached to the cysteinyl part of the molecule, and the oxidized form glutathione disulfide (GSSG). As electrons are lost from the reduced form, two molecules combine to create a dimer formed by a disulfide bridge, the process which can be reversed through reduction of the GSSG. Such electrons are lost during its reaction with free radicals, in which the free radicals are neutralized by the donation of an electron from the oxidized version of glutathione.
The definition of a free radical is a molecule that is lacking one electron from an electronic pair. Its prime purpose is then to steal an electron from the nearest molecule to it. In doing so, it can not only destroy that molecule, but also destroy body cells and lead, not only to premature aging, but also to some potentially fatal conditions.
It is an unusual peptide in that it involves a link between the Cysteine amino grouping and the carboxyl functional group of the glutamic acid. It is a powerful antioxidant, acting as an effective free radical scavenger and protecting the body cells from the effects of free radical oxidation. However, it is on its detoxification effect in the liver that we shall focus here prior to discussing some other uses to which the body puts glutathione in its two manifestations.
Much of the detoxification is connected with the thiol group in the molecule. Take mercury for example. The thiol grouping forms a strong Hg-sulfydryl chemical bond within the liver, in the form of a glutathione-mercury chelate. In this form mercury is unable to exert any toxic effect on the body and can be excreted in the normal manner. The same reactive pathway is followed by other heavy metals that can bond to thiol groupings. In this way L-glutathione can protect the liver from the effects of a number of toxic heavy metals such as cadmium and chromium.
This is an important property of the amino acid, particularly in industrial and urban environments where the population is more prone to exposure to heavy metals than their rural counterparts. However, the end result on the glutathione is that it is removed from the body, and, particularly with city dwellers, a supplement may be required to maintain a healthy concentration of this amino acid in the body and in particular in the liver. Therefore, although L-glutathione is not considered an essential amino acid, in that it is biosynthesized within the body, a supplement is sometimes required, particularly by those who live in large cities.
It is important to consider the form in which the glutathione supplement is administered. This is because of the presence of gamma-glutamyltranspeptidase within the digestive system. This enzyme appears to destroy L-glutathione before it can be absorbed in the intestine so normal oral forms of supplementation are likely to be ineffective. Possible forms of effective administration include buccal (between the cheek and teeth) and hypodermically.
An alternative means of supplementation is to take substances such as selenium, methionine, alpha-lipoic acid, vitamin C and glutamine that stimulate the biosynthesis of glutathione. Also, since the substance utilizes the raw materials of L-Cysteine, glutamic acid and glycine in its intracellular production, supplementation with these amino acids should also help to produce L-glutathione.
That said, let's return to its antioxidant properties and its effect on the liver that contains the largest stocks of glutathione in the body. It is generally regarded as the most important antioxidant in the body. It protects cellular cytoplasm from oxidation by reducing disulfide groups and maintaining a highly reducing environment within the cytoplasm. It reacts with hydrogen peroxide and other oxidative agents, and is converted to the oxidized form GSSG. It is then reduced back to GSH through the combination of the reducing agent and an enzyme. The reducing agent is nicotinamide adenine dinucleotide phosphate (NADPH), the enzyme being glutathione reductase.
The implications that this strong reducing effect has on the liver are significant. Reduced GSH L-glutathione levels have been found in patients suffering from HIV, hepatitis C and other liver diseases. Supplementation with GSH has been found to restore normal levels of glutathione to the liver, and it has been demonstrated that the treatment has improved such conditions significantly.
Atherosclerosis is a condition of the arteries caused by the deposition of plaques formed from oxidized low-density lipoproteins, otherwise known as bad cholesterol. The strong antioxidant effect of GSH prevents this from LDLs from being oxidized and deposited on the arterial wall. There are other results of glutathione supplementation that indicate the effectiveness of antioxidants in the treatment of serious liver conditions, and there are no doubts that combating the effects of free radicals and oxidizing agents within the liver has a positive effect on many potentially serious liver diseases.
Many of these are exacerbated by the generation of free radicals by relatively modern pollution sources such as pesticides, petrol and diesel emissions, tobacco fumes and various other chemical emissions. A strong antioxidant such as L-glutathione cannot be anything other than an effective means of reducing the biological effect of these oxidants. It protects not only the liver but also the lungs and cardiovascular system.
For all these reasons a supplement consisting of L-glutathione or its constituent parts, glutamic acid, Cysteine and glycine, provide significant protection against the stresses and strains of modern living. Increased pollution levels and heightened oxidative stress levels within the body are playing havoc with our body defenses, and GSH is an important one of them that can easily be enhanced by supplementation. There are no known reactions to L-glutathione supplementation, but pregnant women and babies should receive expert medical advice prior to taking it.
April 15, 2009 01:20 PM
Thrombophlebitis is when inflammation occurs in the veins due to the formation of a blood clot in that vein. This problem usually occurs in the extremities, especially the legs. Thrombophlebitis can be considered superficial if it affects the subsutaneous vein, which is one of the veins near the skin’s surface.
In superficial thrombophlebitis, the affected vein can be felt and may be seen as a reddish line under the skin. Additionally, swelling, pain, and tenderness to touch can occur. If widespread vein involvement is included, the lymphatic vessels may become inflamed. Superficial thrombophlebitis is a relatively common disorder that can be brought about by trauma infection, standing for long periods of time, lack of exercise, and intravenous drug use. The risk of superficial thrombophlebitis can be increased by pregnancy, varicose veins, obesity, and smoking. Thrombophlebitis can also be associated with environmental sensitivities to allergies. This condition is usually diagnosed according to physical findings and a medical history that indicates an increased risk.
Deep thrombophlebitis (DVT) affects the intramuscular veins farther below the skin’s surface. DVT is a much more serious condition than superficial thrombophlebitis because the veins affected are larger and located deep within the musculature of the leg. These veins are responsible for the transport of 90 percent of the blood that flows back to the heart from the legs. Symptoms of DVT may include pain, warmth, swelling, and bluish discoloration of the skin of the affected limb. These symptoms are often accompanied by fever and chills. The pain is typically felt as a deep soreness that is worse when standing or walking and gets better with rest, especially with elevation of the leg. The veins directly under the skin may become dilated and more visible. Inflammation situated in a vein in the pelvis is referred to as pelvic vein thrombophlebitis.
The reason or reasons for the formation of the clots in the veins are often unknown. However, in most cases, clots are probably the result of a minor injury to the inside lining of a blood vessel. If the vessel lining receives a microscopic tear, clotting is initiated. Platelets clump together to protect the injured area, and a series of biochemical events is initiated that results in the transformation of fibrinogen, a circulating blood protein, into strands of insoluble fibrin, which are deposited to form a net that traps blood cells, plasma, and yet more platelets. This results in a blood clot. Other possible causes of the formation of DVT include abnormal clotting tendencies; poor circulation; certain types of cancer; and Behcet’s syndrome, which is a condition that affects small blood vessels that predispose an individual to the formation of clots. The following factors increase the risk of DVT: recent childbirth, surgery, trauma, the use of birth control pills; and prolonged bed rest.
The following nutrients are recommended for the prevention and treatment of thrombophlebitis: acetyl-l-carnitine, coenzyme Q10, flaxseed oil, garlic, l-Cysteine, lecithin granules, l-histidine, magnesium, MSM, Pycnogenol, vitamin C with bioflavonoids, vitamin E, zinc, and vitamin B complex. Additionally, the following herbs may be beneficial: alfalfa, pau d’arco, red raspberry, rosemary, yarrow, butcher’s broom, cayenne, ginger, plantain, witch hazel, skullcap, valerian root, ginkgo biloba, goldenseal, hawthorn, and olive leaf extract.
Natural vitamins are a great way to help prevent conditions such as these. If you suspect that you have thrombophlebitis, consult your doctor before trying to take the problem into your own hands. Natural vitamins such as the ones listed above can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
April 05, 2009 01:40 PM
Attention deficit hyperactivity disorder (ADHD) is the newest name that has been given to a group of disorders of the central nervous system. With the long list of names this disorder has been given over the years, it is often confusing as to which criteria are for a diagnosis of ADHD or ADD. It is estimated that between 3 and 5 percent of children in the United States have ADHD, meaning that at least one child in a classroom of twenty-five to thirty children will have ADHD. There are three times as many boys diagnosed with ADHD, but the condition is increasingly being diagnosed in girls as well.
Although ADHD was primarily thought of as a childhood disorder, it can be found in adults as well. Experts have estimated that as many as 8 million adults may be affected, but 80 percent of them do not realize it. Some studies show that there is significant decline in ADHD symptoms as a person ages, while others estimate that between 30 and 70 percent of children with ADHD will carry some symptoms into adulthood. ADHD is a more complex disorder in adults, but it manifests itself into a problem with self-regulation. Without this self-control, an adult’s ability to do tasks is impaired. This condition can lead to marital conflicts, substance abuse, and financial problems. Infidelity is common because ADHD adults easily become bored with things, including spouses.
Factors that have been linked to the development of ADHD include heredity, anxiety, allergies, smoking during pregnancy, hyperinsulinemia, oxygen deprivation at birth, environmental stress or pollutants, artificial food additives, injury, infection, lead poisoning, and prenatal trauma. More emphasis has been placed on the role of diet in ADHD in recent years. Many people with these conditions react to certain preservatives, dyes, and salicylates in foods. These problems can cause the balance of chemistry in the brain to be thrown off, which produces undesirable changes in behavior. A low-protein diet may also be a contributing factor. Although a hotly debated topic for decades, studies have definitely shown that food additives do play a major role in hyperactivity.
Many researchers feel that ADHD is being over-diagnosed nowadays. It is difficult to accurately diagnose this condition because many of the symptoms appear in the normal, healthy children at many times during childhood. In fact, more than 60 percent of parents suspect that their child has ADHD at some point in their upbringing. What may merely be creativity or a high energy level can be diagnosed as ADHD. A diagnosis of ADHD should be made by a team of specialists who are experts in the disorder and it is wise to get a second opinion.
One should considered nutritional deficiencies and dietary measures for treating ADHD. The following nutrients are recommended: calcium, magnesium, GABA, a multivitamin and mineral complex, Omega-3 fish oil, Pycnogenol, Quercetin, SAMe, acetylcholine, DMAE, l-Cysteine, phosphatidyl serine, vitamin C with bioflavonoids, and zinc. Additionally, the following herbs may be beneficial: ginkgo biloba, ginseng, mullein oil, valerian root, catnip, chamomile, gotu kola, hops, kava kava, lemon balm, licorice, lobelia, oats, passionflower, skullcap, St. John’s wort, thyme, and wood betony.
Creating a nutritionally sound diet for children and adults can go a long way to controlling ADHD and ADD in general. Reducing sugar intake and adding good quality food that hasn’t been over processed which removes the needed vitamins, minerals and phytonutrients we all need to live healthy lives. The above vitamins, minerals and herbs are suggested to be helpful for those suffering as well as those who aren’t, but always consult your health care provider before adding dietary supplements to ones diet while on prescription drugs. Quality vitamins can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins, minerals, and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
Fight Inflammation naturally
March 19, 2009 02:36 PM
Lupus is a chronic inflammatory disease that often affects many of the body’s organs. An autoimmune disease, it occurs when the immune mechanism forms antibodies that attack the body’s own tissues. The majority of experts believe that lupus is caused by a virus that has yet to be identified. According to this theory, the immune system develops antibodies in response to the virus that proceed in attacking the body’s own organs and tissues. This causes inflammation of the skin, blood vessels, joints, and other tissues to result. Other possible contributing factors to the development of lupus include heredity and estrogen and testosterone hormones.
This disease was named lupus, which means wolf, due to the butterfly-shaped rash that many people get over their cheeks and nose, which gave them what many people considered to be a wolf-like appearance. However, the rashes may appear elsewhere on the body, including the chest, ears, hands, shoulders, and upper arms. At least 90 percent of those people who contract lupus are women, with women of Asian background appearing to be at greater risk for developing lupus than other women. Although lupus may occur at any age, it usually develops between the ages of fifteen and thirty-five.
There are two different types of lupus: systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE). SLE is a systemic disease that affects many different parts of the body and severity ranging from mild to life-threatening. The first symptoms in many cases of SLE seem to resemble those of arthritis, with swelling and pain in the fingers and other joints. The disease can also appear suddenly, with acute fever and the characteristic red rash appearing across the cheeks. Additionally, there may be red, scaling lesions elsewhere on the body, with sores possibly forming in the mouth.
Other symptoms of SLE include abdominal and chest pains, blood in the urine, fatigue, hair loss, loss of appetite, low-grade fever, nausea, poor circulation in the fingers and toes, shortness of breath, ulcers, vomiting, and weight loss. Many times, the lungs and kidneys are also involved, as about 50 percent of those with SLE develop nephritis, which is inflammation of the kidneys. The brain, lungs, spleen, and heart may also be affected in serious cases. Additionally, SLE can cause excessive bleeding and an increased susceptibility to infection. Amnesia, deep depression, headaches, mania, paralysis, paranoia, psychosis, seizures, and stroke may also be present if the central nervous system is involved.
DLE is a less serious disease, which primarily affects the skin. The butterfly rash forms over the nose and cheeks, with other possible lesions elsewhere, primarily on the scalp and ears. These lesions, which are small, yellowish lumps, can recur or persist for years. When they disappear, they often leave scars or permanent bald patches on the scalp. Although DLE is not necessarily dangerous to overall health, it is a chronic and disfiguring skin disease.
Both types of lupus follow a pattern of periodic flare-ups, with alternating periods of remission. These flare-ups can be caused by the sun’s ultraviolet rays, fatigue, pregnancy, childbirth, infection, some drugs, stress, unidentified viral infections, and chemicals.
In order for a diagnosis to be made, the following eight symptoms have to occur either separately or at the same time: abnormal cells in the urine; arthritis; butterfly rash on the cheeks; low white blood cell count, low platelet count, or hemolytic anemia; mouth sores; seizures of psychosis; sun sensitivity; and the presence of blood of a specific antibody that is found in 50 percent of people with lupus.
The following nutrients are considered to be extremely important in dealing with lupus: calcium, magnesium, l-Cysteine, proteolytic enzymes (Serrapeptase and nattokinase), essential fatty acids, glucosamine sulfate, garlic, raw thymus glandular, vitamin C with bioflavonoids, zinc, acidophilus, kelp, a multivitamin and mineral complex, pycnogenol, vitamin A, vitamin E, alfalfa, goldenseal, burdock root, feverfew, pau d’arco, red clover, licorice root, milk thistle, and yucca.
Natural alternatives can help support the body in the fight against lupus, but one should always consult a physician before taking matters into their own hands regarding this disease. Natural supplements like the ones listed above can all be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
B Vitamin Complex
June 23, 2008 03:19 PM
The vitamin B supplement you take is a mixture of nutrients that, although they share the same vitamin letter, are in fact distinctly different chemical entities. The reason that they share the same reference letter of the alphabet is that they are all essential water soluble vitamins (Vitamin C being the only other), they frequently work in synergy with each other and they often come from common sources and have similar properties in the body. They were therefore at one time believed to be just the one chemical entity.
They are essential in that they must form part of our diet because our bodies cannot manufacture these substances from others, and although most share common biochemical and health functions, there is no health function that requires all of them, and none of them can be totally replaced by another.
The B-Vitamin complex that you take can consist of as many as eight different B vitamins, each of which is essential for a healthy body and at one time it was believed that this mixture was only one single vitamin. That is why they are collectively known as vitamin B and were subsequently allocated numbers: it was only later that the individual components were discovered.
These eight are vitamin B-1 (thiamine), vitamin B-2 (riboflavin), vitamin B-3 (niacin), vitamin B-5 (pantothenic acid), vitamin B-6 (pyridoxine), vitamin B-12 (cobalamins), biotin and folic acid (folate). They are found in yeast, liver, tuna, bananas and rice among other sources, and, as with all vitamins, without them life would not be possible. Not all vitamins are found in each of these food sources, and vitamin B-12, for example, is available in nutritional quantities only from animal sources.
Knowing what they are is all very well, but what does your body do with the B vitamin supplement that you take? Before considering that, the reason that a regular supply is important is because of their water solubility. This is a useful property for a vitamin to possess, because it means that they can easily be transported by the body fluids to the tissues where they are needed. The downside, however, is that they are consequently also easily flushed from the body, and your body cannot store any of the B vitamins.
You therefore must have a regular dietary source that can be augmented through supplementation. This is particularly desirable in alcoholics, those on diets to lose weight and vegans who are advised to take a regular vitamin B-12 supplement.
A lack of vitamin B will make you feel tired and lack energy because they play a big part in your body’s metabolism of blood glucose into energy. They also help to maintain a healthy immune system, keep your nervous system in tip-top condition and maintain good healthy skin, hair and muscles. The B complex is also very important in maintaining healthy blood and liver, and each and every component of the mixture has a specific part to play, both on individually and by interaction with others in the B complex.
Rather than examining what your body does with the supplement as a whole, let’s have a look at each component, and what your body does with that. Taking them one at a time, thiamine (B1) helps you to burn carbohydrates to generate energy. It is highly water soluble and must be taken daily. In the form of thiamine pyrophosphate it plays a key part in the metabolism of carbohydrates to energy, and also in the metabolism of certain amino acids. If you rely heavily on a high carbohydrate diet, you will need a good regular supplement of thiamine to be able to convert them to energy.
Vitamin B2 (riboflavin) also plays a part in fat and carbohydrate metabolism and the formation of adenosine triphosphate (ATP), the molecule of energy. It plays a significant part in the health of your skin and a deficiency is associated with mouth ulcers, cracked lips, flaky skin and bloodshot watery eyes. It also activates vitamin B6 and folic acid, one of the cases where the B vitamins work together synergistically.
Vitamin B3, or niacin, is well known to women as a component of some shampoos, and helps to promote health hair. However, this vitamin also takes part in the process of energy creation within your body, and helps to maintain a good muscle tone within the digestive tract. It is also used as a supplement for the treatment of diseases related to high levels of LDL cholesterol and is useful for the treatment of atherosclerosis.
Pantothenic acid is also found as a component of shampoos, so no prizes for guessing one of its functions. Vitamin B-5 plays a significant part in the energy-producing Krebs Cycle, or Citric Acid Cycle, that is used by every cell in your body to generate energy just where it is needed. It is also needed to synthesize acetylcholine, a neurotransmitter needed for good brain function and it helps to reduce stress. Pantothenic acid is also closely involved in the production of cholesterol in your liver: cholesterol is not all bad, and is needed by your body to produce some of the steroid hormones and also vitamin D.
Amino acids are the small units that are used to biosynthesize proteins and ultimately the genes and DNA that determine who you are. The major factor involved in processing these amino acids is Vitamin B6 (pyridoxine), one of the lesser known of the vitamin B complex. It synthesizes and breaks up different amino acids to produce a variety of other compounds, such as the hormones serotonin, melatonin and dopamine.
Deficiencies in these hormones can be very serious, Parkinson’s disease believed to be connected with a dopamine deficiency for example, and other disorders include kidney stones, anemia and many skin complaints. Although deficiency of vitamin B6 is rare, it can occur in alcoholics and those with chronic kidney problems. It is believed that many diets are deficient, however, and a good vitamin B supplement would ensure that this did not occur.
Vitamin B-12 is one where deficiency can occur, particularly in alcoholics and vegans. It is available in sufficient quantities only from meat sources, and a supplement is indicated in anyone with a low meat intake in their diet. It is used by your body for the replication of DNA and to allow the normal activity of your body cells. It also helps to control homoCysteine levels in conjunction with vitamin B6 and folic acid: homoCysteine is a high-risk amino acid associated with atherosclerosis and cardiovascular disease that can lead to Alzheimer’s disease, heart attacks and strokes.
The seventh, biotin (sometimes referred to as vitamin B7) also takes part in the metabolism of energy, but deficiencies have not been known, and the final known member of the B vitamin complex is folic acid. This is essential for cell growth and the synthesis of RNA and DNA in the body. RNA (Ribonucleic acid) is responsible for the synthesis of proteins in your body, and the well known Deoxy-ribonucleic acid (DNA) holds the genetic information of your body. Folic acid is therefore essential in the growing fetus, and any other cellular system that rapidly regenerates such as blood cells and the various cells of the immune system.
Without folic acid your body would be more susceptible to bacterial and viral attack, and less able to protect you from foreign invaders into your body tissues. Although deficiency is not common, folic acid is present in fresh food only and degrades when stored at room temperature and when cooked. A supplement is therefore advisable during pregnancy to help to prevent neural tube defects.
It is evident that the Vitamin B complex plays many parts in the chemistry of your body, and that a supplement can be of benefit in assuring that there are no deficiencies. A good B complex can be found at your local or internet health food store.
Supports Healthy Blood Pressure
April 18, 2008 03:59 PM
3 tablets contain:
Suggested Use: 3 tablets mid-morning and 2 tabs mid-afternoon between meals on an empty stomach.
April 08, 2008 08:41 PM
A unique blend of compounds, including alpha-lipoic acid, N-acetyl Cysteine, quercetin, and grape seed extract, which is designed to reactivate and recycle vitamin C in the body, making it more available for immune support and free radical scavenging.
The well-known benefits of vitamin C are recharged in this formula, which is designed to make more vitamin C available for immune support and free radical scavenging. The unique blend of compounds in systemic C may reactivate and recycle vitamin C in the body, providing increased antioxidant activity for healthy aging, heart health and immune support.
Vitamin C (as calcium ascorbate) 1 g
Systemic C - Vitamin C with Optimized Vitamin C Activity!
March 28, 2008 04:22 PM
What could be even better than vitamin C? source naturals systemic C, of course, a vitamin C that is designed to upgrade the important benefits of this powerful antioxidant. The systemic C formula is designed to make more vitamin C available for immune support and free radical scavenging.
After vitamin C carries out its antioxidant function of neutralizing free radicals, it is oxidized and spent. The unique blend of compounds in systemic C, including alpha lipoic acid, n-acetyl Cysteine, quercetin, and grape seed extract, helps to reactivate and recycle vitamin C in the body. this provides the body with increased antioxidant activity, an upgraded, robust C for healthy aging, immune, heart, and skin health. Reactivating vitamin C allows this important vitamin to continue its vital functions.
L-Glutathione Can Eliminate Toxins in the Liver
December 07, 2007 11:54 AM
L-glutathione is the reduced form of glutathione, and is a tripeptide synthesized in the animal and plant tissues from glycine, Cysteine and glutamate. Commonly known as GSH, it contains thiol groups that are maintained in a reduced state, and is a very powerful antioxidant, considered to be the key antioxidant and protective substance in the body.
Glutathione can reduce any disulfide groups in the cytoplasm within the body of the cell, and ensures that the cytoplasm is a strongly reducing medium protecting against oxidation. It has a synergistic effect with other antioxidants to protect the body against free radicals and oxidizing agents that cause so much damage to the body through what is commonly referred to as ‘oxidative stress’. However, there is more to it than that and it attaches itself to toxic chemicals and drugs in the liver and renders them into a state suitable for elimination from the body.
These toxic materials include poisonous pesticides, hydrogen sulfide, carbon monoxide, heavy metals such as mercury, cadmium and chromium and many other substances that we come into contact with due to present day pollution of our atmosphere and foodstuffs. Glutathione can also help protect the body from the effects of chemotherapy and evidence is suggesting possible links with the control of some cancers, diabetes, atherosclerosis and many other degenerative conditions caused by free radical attack and the effects of pollutants.
The way that GSH acts in the cells is that the redox state of the glutathione-glutathione disulfide couple is critical to the health of the intercellular and intracellular fluid. GSH in the reduced state of glutathione reacts with an oxidative agent such as hydrogen peroxide to form the oxidized form, glutathione disulfide and water. It hence mops up oxidizers such as peroxides and free radicals within the cytoplasm of the body’s cells, and also in between the cells. The disulfide is then converted back to GSH by the combined action of the enzyme glutathione reductase and NADPH (the reducing agent nicotinamide adenine dinucleotide phosphate).
The cycle then repeats so that two molecules of glutathione continue to reduce damaging oxidizing agents without themselves being consumed. In so doing, the NADPH becomes oxidized. A continuous supply of NADPH is needed to allow GSH to undergo these biochemical reactions, and up to 10% of our blood glucose is used by the pentose phosphate pathway by which NADPH is synthesized.
Since this cycle consumes no glutathione, it would appear that a supplement is unnecessary. However, this is not the case since the molecule takes part in other reactions in the body, particularly in the elimination of toxic heavy metals from the body. Mercury is highly reactive with the thiol that GSH is, and so will bind to form a stable Hg-sulfydryl bond in the liver. This mercury-glutathione chelate is unable to bind to other proteins or gain access to the body cells, and is eventually harmlessly secreted. The same is true of many other heavy metals that are reactive with thiol’s.
In this way the body is protected from the harmful effects of these heavy metals. However, it results in the loss of the glutathione, and the pollution of modern day living can take a heavy toll of the GSH content of our bodies. For this reason a glutathione supplement is recommended, especially for city dwellers that may be exposed to more heavy metals than those residing in rural areas.
However, the form in which this supplement is taken is very important, because the human digestive tract contains a significant amount of gamma-glutamyltranspeptidase. That is an enzyme which apparently destroys glutathione before it can be absorbed. However, it can be absorbed directly into the bloodstream by dissolving the pill between the teeth and inner cheek. It has also been suggestion that the supplement could be administered by injection.
Others have suggested that rather than administer a supplement, individuals could take other supplements that contain the materials needed to stimulate the formation of GSH. Substances such as vitamin C, selenium (important in GSH biochemistry), methionine, alpha-lipoic acid and glutamine could all help to increase the body’s production of glutathione. A supplement of the constituent parts of Cysteine, glycine and glutamic acid should also help. The dosage ranges recommended vary widely from 50mg to 500mg daily, and the effects of supplementation are not yet well know.
Some specific conditions that this wonder antioxidant is useful in treating include liver disease such as hepatitis, cirrhosis and so on. Patients suffering from these diseases show a massive reduction in their GSH content and prior GSH treatment appeared to offer a significant degree of protection in controlled clinical investigations. Patients suffering from chronic hepatitis C have been found to be associated with reduced GSH levels, particularly if also HIV positive.
Similar deficiencies have been noted in some lung conditions such as asthma and other pulmonary conditions. In such cases it has been demonstrated that administration of GSH supplements sufficient to restore normal levels of the substance improved the patients’ conditions by a significant amount. Its effect on atherosclerosis appears to be significant since a decreased level of GSH peroxidase has been recorded in such patients in addition to an increase in lipid peroxides, indicating that oxidation of the arterial wall had been occurring.
Anti-viral therapies that rely on GSH biochemistry for their action have been found to be less effective in those with low GSH levels, and other studies have confirmed that supplementing with GSH improves the response to interferon treatment. These results indicate the activity of oxidizing agents and free radicals in liver conditions, and in fact this has been demonstrated by tests carried out in New York and Philadelphia in the 1990s.
This suggests that the liver is prone to damage by oxidative stress, and that GSH levels may be able to be used as an indication of potential liver disease. What is evident is that a strong case can be made for glutathione supplementation as protection against potential liver, pulmonary and cardiovascular diseases, especially by those exposed to specific polluting agents such as primary or secondary tobacco smoke, auto and diesel fumes and chemicals and pesticides.
L-glutathione is useful, not only for the elimination of toxins in the liver, but also in protecting this large and vital organ from the oxidative stress that modern living brings. L-Glutathione and its precursors are sold over the counter at your local or internet health food store.