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Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?
Date:
December 07, 2023 12:12 PM
Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body. While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption. GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age. The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels. In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body. This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form. But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them. So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing! Liver HealthWhen it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ. Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds. During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances? But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker! The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning. So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being! Alcohol IntoxicationAlcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells. To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes. The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group. The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver. Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels. Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy. In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management. Beautiful SkinBy activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions. Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores. Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects. Skin LighteningSkin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract. The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women. In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH. Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin. The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities. In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592) six top-notch supplements that can help you achieve your goals.
Date:
December 06, 2023 04:55 PM
If you're looking to stay in the game longer and improve endurance while promoting rapid recovery, we've got you covered! six top-notch supplements that can help you achieve your goals.For most of us, life can feel like quite the balancing act. In an ideal world, we would all have ample time throughout the day to dedicate to our health and well-being. However, reality paints a different picture, where 24 hours can seem like an insufficient amount of time to squeeze in work, school, family, and the countless responsibilities that life throws at us. In recent years, the use of supplements for recovery has gained popularity, becoming more common than ever before. Our bodies face a barrage of daily stresses, including exposure to environmental toxins, electromagnetic pollution, and the strain of intense physical activity. These factors increase our body's demands for antioxidants and essential nutrients that aid in the process of recovery. While consuming antioxidant-rich foods can certainly make a difference, it can be challenging to meet these requirements solely through our diet. That's where a well-rounded supplement regimen can play a crucial role in promoting optimal health and aiding in recovery. Even with our best efforts to exercise regularly, eat nutritious meals, and get sufficient sleep, life in the 21st century can be incredibly demanding, depleting our bodies on a cellular level. For athletes, consistent training is key to reaching desired performance levels. It's important to understand that the muscle recovery and building process primarily occurs between gym sessions. Developing a comprehensive recovery strategy during this crucial window, through the use of supplements, proper nutrition, and adequate rest, can help athletes perform at their best week in and week out. Failing to make the most of this recovery period may result in free radical damage and delayed onset muscle soreness (DOMS). To maximize the benefits, it's important to prioritize food as the primary source of vital nutrients, while also recognizing the significant role supplements can play in providing the necessary building blocks for muscle repair due to their rapid absorption rate. However, it's essential to ensure that any chosen supplements are clinically validated, demonstrating efficacy and supported by solid scientific evidence. In today's fast-paced world, there is a growing demand for quick and convenient solutions to jumpstart the recovery process. Nevertheless, when it comes to choosing supplements, it's important to remember that one size does not fit all. The market offers an overwhelming array of options, often leaving individuals feeling bewildered about which products to select. Before diving into my recommendations for the top six supplements to aid in recovery, I believe it's crucial to emphasize the significance of cellular renewal and its direct impact on the recovery process. This, in my opinion, serves as the key to achieving a quick and effective recovery. Oxidation and Free Radical DamageA fundamental key to staying young and maintaining optimal health is cellular renewal and minimizing the damage to cells over time. We all age, but studies have shown that some individuals age better than others. Have you ever wondered why? Well, recent research has linked oxidative stress to the aging process. So, what exactly is oxidative stress? Allow me to explain in simple terms – oxidation occurs when the body produces by-products commonly known as free radicals. It's almost like a machine rusting, but instead of rust forming on iron, our bodies experience the effects of aging and age-related diseases. Now, our bodies naturally produce free radicals as part of our daily metabolism, and they can also be produced as a result of environmental pollutants from everyday things like air, water, and even sun exposure. As we age, our bodies become more vulnerable to the long-term effects of oxidative stress, which simply means we accumulate too many free radicals and experience increased inflammation at the cellular level. As interesting as it may sound, the process of oxidation is actually abundant and can be beneficial for our bodies to function properly. But, and this is an important "but," this very process can also cause potential harm. You see, the oxidizing process creates these molecules called free radicals, which are electrically charged. These free radicals interact with our cells, and this interaction can lead to both positive and negative outcomes. For example, our immune system utilizes free radicals to help fight infection. However, when LDL cholesterol (often referred to as bad cholesterol) is oxidized, it can become a concern (cholesterol buildup). Let's talk about oxidative stress. It occurs when the level of free radicals overwhelms the body's natural antioxidant defense system, resulting in cell damage. As I mentioned earlier, while free radicals serve useful functions in the body, they are highly unstable molecules. If they remain uncontrolled, they have the potential to wreak havoc by causing damage to cells, enzymes, and even our DNA, which ultimately accelerates the aging process. In addition, these free radicals can also contribute to the development of various age-related diseases, including arthritis, cancer, and heart disease Now, inflammation is triggered by free radical damage, and it is this inflammation that leads to the negative effects of free radicals due to oxidation. The question then becomes, how can we address this in our daily nutritional regimen? The answer lies in the incorporation of antioxidants, which play a vital role in combating oxidative stress and minimizing the damage caused by free radicals in our bodies. You'll be glad to know that there are foods rich in antioxidant content that can help us on this journey. In fact, certain foods contain phytonutrients that, according to many health professionals, hold the potential to unlock the secrets of longevity and overall well-being. So, my dear friend, let's take a proactive approach, nourish our bodies with antioxidant-rich foods, and strive to minimize the effects of oxidative stress caused by free radicals. It's never too late to make positive choices for our health and age gracefully. Phytonutrients, also known as health boosters, are substances produced by plants to protect themselves from harmful bacteria and viruses. However, these compounds also offer significant benefits to the human body. Packed with essential nutrients, phytonutrients play an active role in promoting good health. They belong to the antioxidant family, responsible for eliminating harmful free radicals and thus slowing down the aging process. Incorporating a diet rich in high antioxidant foods like fresh fruits and vegetables is crucial as the first line of defense against aging. While vitamins A, C, and E are commonly known antioxidants, there are other antioxidants available in both food and supplement form. These antioxidant supplements play a vital role in bridging the nutritional gap left by processed foods, lacking the necessary antioxidants and nutrients to combat free radicals effectively. Let's take a closer look at my top six supplement recommendations, known for their efficacy in fighting oxidative stress and promoting optimal recovery: Beta Alanine: As an amino acid derivative, Beta Alanine is proven to enhance intramuscular carnosine content, improving the body's ability to buffer hydrogen ions. During exercise, the body accumulates hydrogen ions, contributing to fatigue and lowering pH levels. Beta Alanine supplementation can reduce fatigue, enhance exercise performance, and increase training volume. Whether it's interval training or weightlifting to improve running economy, incorporating beta-alanine can have a positive impact on endurance performance and overall training results. BCAAs: Branched Chain Amino Acids (BCAAs) have become a staple supplement for athletes due to their role in muscle and energy production during exercise. Consisting of three essential amino acids - leucine, isoleucine, and valine - BCAAs have been shown to significantly reduce muscle soreness and expedite the recovery process. Supplementing with BCAAs helps prevent muscle breakdown, as the body does not need to rely on its own muscle tissue for energy. Consequently, protein synthesis remains high, supporting muscle growth and repair. Creatine, a natural molecule found in muscle cells. When engaging in high-intensity workouts like weightlifting, Creatine helps your body produce adenosine triphosphate (ATP), a vital energy source. This amazing compound improves strength, boosts lean muscle mass, and aids in faster muscle recovery. Flavonoid Root, a breakthrough extract known for its cardiovascular benefits. This extract is packed with potent antioxidants and acts as a nitric oxide booster, promoting increased endurance during workouts. Studies have shown that it fights against free radical damage and increases the flow of oxygen-rich blood, ensuring optimal cardiovascular health. You can also boost nitric oxide with beet root, and l-citruline. Speaking of studies, a published research paper in Food and Nutrition Research (April 2016) highlighted the effects of the unique flavonoid root extract on arterial health. The study revealed that after one year of consumption, participants experienced a decrease in artery wall thickness, total cholesterol, LDL levels, and blood pressure. This indicates that the extract may help reduce the risk of oxidation-related cerebral vascular issues and improve overall cardiovascular health Glutamine. It's the most abundant amino acid in the human body and plays a vital role in muscle recovery and repair. Glutamine aids in preventing muscle soreness, optimizing post-workout recovery, and supporting muscle rebuilding. By facilitating nitrogen transport, regulating acid-base balance, and acting as an antioxidant, Glutamine ensures faster post-workout muscle recovery, giving you the freedom to train harder for better results. Protein plays a crucial role in replenishing and repairing your muscles after a workout, making it a key nutrient to consume alongside carbohydrates. By opting for a protein shake as a post-workout option, you can efficiently supply amino acids to your muscles, stimulating muscle protein synthesis, enhancing recovery, and promoting growth. It's important, though, to choose a protein shake that contains high-quality ingredients, as prioritizing quality over quantity is key when it comes to protein. Apart from protein, there are several other supplements that work through various mechanisms to provide natural, broad-spectrum antioxidant and nutrient support, ultimately contributing to optimal health and recovery. Taking preventative measures to protect the health of different body systems is much easier than trying to restore their function after damage has occurred. With this in mind, retailers should suggest a preventive program to their customers, aiming to limit free radical damage and promote recovery. As the adage goes, "an ounce of prevention is worth a pound of cure," emphasizing the significance of protecting and preserving one's health. In conclusion, the role of antioxidants, particularly phytonutrients, in maintaining overall health and combating oxidative stress cannot be overstated. These beneficial compounds not only slow down the aging process, but also enhance the body's ability to recover from physical exertion. Various supplements, including Beta Alanine, BCAAs, Creatine, Flavonoid Root, Glutamine, and Protein, each offer distinct benefits in supporting muscle growth, improving athletic performance, and promoting quicker recovery. The incorporation of these supplements into one's regimen can effectively bridge the nutritional gap left by processed foods. A preventive strategy, emphasizing a diet rich in antioxidants and high-quality supplements, holds the key to optimal health and longevity. As the saying goes, 'an ounce of prevention is worth a pound of cure'.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6591) Unlocking the Benefits of Green Tea Extract
Date:
August 10, 2023 10:43 AM
With the growing awareness about the health benefits of green tea, it comes as no surprise that it has become a popular health supplement. One potent green tea supplement that has continued to maintain attention is Natures Answer brand Green Tea Extract in an Alcohol-Free Liquid Extract. Packed with powerful antioxidants, this supplement can aid in digestion, weight management, and overall well-being. Powerful Antioxidant Antioxidants are substances that inhibit oxidation, a process that can lead to cellular damage. They act as scavengers, helping shield the body from harmful free radicals, which are unstable molecules that can inflict damage to our cells. This is where green tea, and particularly green tea extract, shines. Rich in antioxidants known as polyphenols, green tea plays a significant role in maintaining the body's overall health. Polyphenols, including flavonoids and catechins, are known for their potent antioxidant effects. The most notable catechin in green tea is Epigallocatechin Gallate (EGCG), widely studied for its powerful impact on health. Green tea's antioxidants help neutralize harmful free radicals, reducing oxidative stress, and subsequently lowering the risk of a host of chronic conditions including heart disease, type 2 diabetes, and even certain cancers. Thus, the antioxidants in green tea aren't just important, they're an integral part of a health-conscious lifestyle. Boost Immune System Green tea boosts immunity through its potent bioactive compounds, primarily polyphenols like catechins. These compounds exhibit powerful antioxidant properties, neutralizing harmful free radicals in the body. Additionally, they help increase the body's production of detoxifying enzymes, further enhancing the immune system's efficiency. Green tea also contains a type of catechin called Epigallocatechin Gallate (EGCG), renowned for its immune-boosting properties. EGCG aids in the production of T-cells, the body's first line of defense against infections. Furthermore, green tea fosters beneficial gut bacteria, which play a crucial role in maintaining a robust immune system. Promotes Weight Loss Green tea extract works to accelerate weight loss primarily through its active ingredients, one of which is caffeine. Although not as much as coffee, green tea does contain sufficient caffeine that can aid in fat burning and improving exercise performance. More importantly, it is loaded with potent antioxidants called catechins. The most important of these is Epigallocatechin gallate (EGCG), a substance that can boost metabolism. Studies suggest that the combination of EGCG and caffeine in green tea extract can assist in weight loss by helping the body burn more calories, even at rest, and breaking down more fat cells. Additionally, green tea extract is known to increase fat oxidation and improve insulin sensitivity, both beneficial for weight control. While the effects on each individual can vary, when combined with a balanced diet and regular exercise, green tea extract can indeed support and accelerate weight loss efforts. Impacts Central Nervous System Green tea extract is known to have profound effects on the central nervous system, primarily due to the presence of caffeine and an amino acid called L-theanine. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter in the brain called Adenosine. This increases the firing of neurons and the concentration of neurotransmitters like dopamine and norepinephrine, leading to improved brain function, mood, vigilance, reaction times, and even memory. On the other hand, L-theanine can cross the blood-brain barrier and has been shown to increase the activity of the inhibitory neurotransmitter GABA, which has anti-anxiety effects. It also increases dopamine and the production of alpha waves in the brain. The unique combination of these two compounds in green tea extract is believed to make it an excellent tool for maintaining and enhancing the central nervous system. Improve Mental Efficiency Green tea improves mental efficiency through several biological mechanisms. Primarily, it contains caffeine and L-theanine, two compounds known to enhance brain function. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter called adenosine, which not only increases the firing of neurons but also amplifies the concentration of other neurotransmitters like dopamine and norepinephrine. This results in improved brain function, vigilance, reaction times, memory recall, and mood. On the other hand, L-theanine is an amino acid that can cross the blood-brain barrier and has psychoactive properties. It promotes relaxation without drowsiness and can work synergistically with caffeine to enhance brain function. Furthermore, L-theanine increases the frequency of alpha waves in the brain, which leads to improved creativity and problem-solving abilities. Moreover, green tea is rich in polyphenols and antioxidants, particularly Epigallocatechin Gallate (EGCG), which has protective effects on neurons, potentially lowering the risk of neurodegenerative disorders like Alzheimer's and Parkinson's disease. Hence, regular consumption of green tea or its extract can significantly improve mental efficiency. Promotes Heart Health Natures Answer Green Tea Extract Alcohol-Free Extract can help you maintain healthy cholesterol levels, reduce high blood pressure, and prevent blood clot formation that can lead to heart diseases. The polyphenol and catechin compounds in green tea extract are known to promote the health of the heart by reducing inflammation and improving blood vessels' function. Green tea maintains healthy cholesterol levels by inhibiting the absorption of cholesterol in the digestive tract and aiding in its excretion. This leads to a reduced level of LDL (bad cholesterol) in the bloodstream, while not affecting the levels of HDL (good cholesterol). Green tea extract can also lower blood pressure. The catechins it contains help to dilate blood vessels, improving their function and allowing blood to flow more easily. This can lead to a significant reduction in blood pressure, especially in cases of hypertension. Furthermore, studies have shown that the antioxidants in green tea can prevent the oxidation of LDL cholesterol, a process that contributes to the formation of plaques in arteries and blood clot formation. By preventing this oxidation, green tea extract can reduce the risk of heart diseases and strokes. Lastly, the anti-inflammatory nature of green tea's antioxidants helps in reducing inflammation in blood vessels, a condition that can contribute to heart disease. By reducing inflammation, blood flow improves, and the risk of heart disease decreases. In this way, green tea actively promotes heart health. In conclusion, Natures Answer Green Tea Extract is an all-in-one supplement that can enhance your overall health and well-being in various ways. The antioxidant, anti-inflammatory, and weight management properties of this supplement can do wonders for your physical, neurological, and mental health. Incorporating Natures Answer green tea (alcohol free) liquid extract into your daily routine can help you unlock the multiple benefits that this tea has to offer. So, go ahead, give it a try, and reap the benefits of this powerful supplement!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6585) Curcumin and Grapeseed
Date:
September 01, 2020 11:03 AM
Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society. Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone. Two top suggested natural medicines available right now are curcumin and grape seed extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and grape seed extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous. Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation. Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells. Curcumin Must Be Absorbed To Be Useful One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil. Curcumin Makes Chemo More Effective There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells. Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news! Curcumin Protects The Body During Cancer Treatment In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective. The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement. At the end of the treatment which lasted 20 weeks the most dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6362) Broccoli is a powerful anti-aging food that you should be eatingevery day
Date:
May 17, 2019 04:00 PM
Broccoli is loaded with anti-aging ingredients such as antioxidants and collagen. Broccoli is known for its nutrition as it is packed with vitamins A and C as well as calcium and iron. The body uses vitamin C to produce collagen, which affects the outward appearance of people. The plant's antioxidants can work as an anti-inflammatory for the body, and they also get rid of free radicals which helps lessen the risks of oxidation in your cells and tissues. Key Takeaways:
"A member of the cruciferous vegetable family, broccoli is completely edible from the crowded clusters of dark green florets at its top to the very tip of its stem. It provides a lot of nutrition, being filled with vitamin A and vitamin C, and containing large amounts of calcium and iron." Read more: https://www.naturalnews.com/2019-04-15-broccoli-is-a-powerful-anti-aging-food-that-you-should-be-eating-every-day.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6330) Pu-erh tea has hepatoprotective and antioxidant properties
Date:
May 14, 2019 04:25 PM
Yunnan Tasly Deepure Biological Tea Group Company recently collaborated with scientists from Tianjin University of Commerce on research into the health benefits of pu-erh tea. The research involved rats on a high fat diet, and discovered that pu-erh tea can help defend your liver against oxidative stress and high glucose levels. Pu-erh tea also appears to be able to protect rats from weight and body fat increases and prevent lipid peroxidation. These results suggest pu-era tea has great potential for preventing fatty liver disease. Key Takeaways:
"The results showed that the treatment with Pu-erh tea extract prevented the increases of body weight and fat index, reduced oxidative stress, and inhibited lipid peroxidation — all of which contributed to the protection of the liver in rats." Read more: https://www.naturalnews.com/2019-04-16-pu-erh-tea-has-hepatoprotective-and-antioxidant-properties.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6317) Study: Taking protein supplements before going to the gym can leadto improved post-workout burn
Date:
May 03, 2019 04:08 PM
Recent research published in the Journal of the International Society of Sports Nutrition indicates that taking your protein supplement before working out can help increase your body’s fat oxidation. In a study of 11 college-aged males who took either whey or casein protein supplements prior to moderate exercise, it was found that both post-exercise fat oxidation and post-exercise energy consumption improved. Casein has more of an impact in this study than whey. This strongly suggests you should take your protein supplement before exercising. Key Takeaways:
"Published in the Journal of the International Society of Sports Nutrition, the study looked at the effect of taking protein supplements before exercise on fat oxidation and energy expenditure during and after a bout of moderate-intensity exercise. Previous research has shown that pre-exercise protein consumption may promote fat oxidation, at the same time, minimize protein degradation during exercise." Read more: https://www.naturalnews.com/2019-03-26-protein-supplements-before-gym-improve-post-workout-burn.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6253) Eating more antioxidant-rich foods can reduce your risk of kidney cancer by 32%
Date:
March 14, 2019 02:28 PM
Want to know the secret to reducing your risk of kidney cancer by 32%? It's not as difficult to conquer this secret as you might think. To reduce your risks, simply add more antioxidant rich foods to your diet. These foods are great additions to your diet and with so many choices, it is easy to eat a variety of foods that taste great and that you love that also keep you health and reduce kidney cancer risks! Key Takeaways:
"Now, a new study review has shown that antioxidants are especially potent against kidney cancer." Read more: https://www.naturalnews.com/2019-01-02-eating-more-antioxidant-rich-foods-can-reduce-your-risk-of-kidney-cancer-by-32.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6076) Daily green tea consumption found to slash dementia risk by up to86%
Date:
January 10, 2019 04:26 PM
Green tea has long been touted for its many health benefits. It is full of antioxidants that help remove oxidation and free radicals from the body system. New studies reveal that it is also very effective in offsetting the risk factors of developing dementia later in life. Dementia effects the brain's memory system and in later stages the body's neurological system. Green tea helps to break down the plaque like build up of beta amyloid in the brain by over 80% and reducing the risk of development of dementia by over 50% in patient populous with a genetic history. Key Takeaways:
"Beta-amyloid plaques is shown to trigger the onset of cognitive disorders in patients. Researchers note similar effects regardless of whether the tea was green or black." Read more: https://www.naturalnews.com/2019-01-02-daily-green-tea-consumption-found-to-slash-dementia-risk-by-up-to-86-percent.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5953) The science behind curcumin’s healing properties
Date:
January 02, 2019 05:17 PM
Nature provides many healing aids, and this spice is among one of the more useful.it has been used for thousands of years to fight and relieve inflammation and has recently been proven effective in preventing oxidation in the circulatory system brought on by smoking and diabetes. It has also proven effective in the tumor reduction treatment in certain cancer lines, which reversing the effects of oxidative stress has shown remarkable progress in the treatment and prevention areas. Key Takeaways:
"Now, two studies published in the African Journal of Traditional, Complementary and Alternative Medicines have confirmed that curcumin also has potent antitumor abilities, in addition to protecting the heart against oxidative stress caused by diabetes and nicotine." Read more: https://www.naturalnews.com/2018-12-30-the-science-behind-curcumin-healing-peoperties.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5922) Compelling study confirms the therapeutic effects of curcumin inremoving fluoride from our bodies
Date:
December 03, 2018 02:03 PM
According to statistics recently released by the CDC, 66.3% of U.S. citizens are being exposed to fluoride poisoning through the country's public water supplies. The good news is that a study in Pharmacognosy Magazine points to curcumin as a natural solution to this growing problem. According to this Indian study, curcumin can protect our brains from fluoride poisoning. If you cannot afford to install a whole-house water filter in your home, curcumin may be a safe and affordable option to protect your family from the dangerous neurological effects of fluoride. Key Takeaways:
"The researchers looked specifically at fluoride-induced toxicity on the mice’s brains, including the chemical’s impact on lipid peroxidation, or rancidity, in brain tissue. They also evaluated markers of malondialdehyde, or MDA, a well-known marker of oxidative stress and oxidative damage, in the brains of mice from each test group." Read more: https://www.naturalnews.com/2018-11-26-curcumin-removing-fluoride-from-the-body.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5869) The health benefits of eating pecans
Date:
August 03, 2018 09:53 AM
Pecans originate from the Midwestern part of the US, and their health benefits are shown to be quite substantial. Pecans are high in vitamin E, which causes them to have large amounts of antioxidants properties. They can also help clean and regulate oxidation processes in order to help contribute to the prevention of various cancers. Studies have indicated that consumption of pecans may also have the ability to help those with liver damage, but it has not been proven in human subjects as of right now. Key Takeaways:
"Referred to as Carya illinoinensis in scientific literature, pecans are a member of the Juglandaceae family, which makes it a relative of the hickory and the walnut. Pecans are also considered native to North America; their existence has predated even the earliest human settlements." Read more: https://www.naturalnews.com/2018-06-11-the-health-benefits-of-eating-pecans.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5689) 9 Reasons To Start Washing Your Face With Honey
Date:
July 17, 2018 09:54 AM
Honey may be made up of 80% sugar, but that does not take away from its amazing benefits when it comes to cleansing and protecting your skin. Honey can be much more gentle when compared to over-the-counter cleansing products, and it has natural defenses such as antibacterial compounds that cause it to be a great way to avoid potential breakouts. Honey is also full of antioxidants such as polyphenols which will help you avoid any oxidative damage that you may experience. Key Takeaways:
"It doesn’t matter what type of skin you have — whether it’s dry, oily, acne-prone, sensitive, inflamed, aging — there’s no one who can’t get better skin with honey." Read more: https://www.thealternativedaily.com/9-reasons-to-start-washing-your-face-with-honey/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5669) Vitamin E: A Closer Look at Tocotrienols
Date:
October 21, 2017 10:14 AM
Researchers have made an estimate and guessed that there are 75 trillion cells in the body. Each of those cells is surrounded by a membrane that is bean shaped. This membrane is made up of dense rows of fatty acids. These require protection from lipid peroxidation. Vitamin E is one of the popular antioxidants. Vitamin E is shaped like a tadpole, which is the perfect shape to do this job. There are two forms of Vitamin E. Key Takeaways:
"In this study, researchers found that alpha-tocopherol, when co-administered with tocotrienols, reduced tocotrienols’ inhibitory effect on HMGR." Read more: http://www.nutritionaloutlook.com/vitamins-minerals/vitamin-e-closer-look-tocotrienols
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5355) Olive oil for a healthy heart
Date:
July 30, 2017 04:14 PM
The use of olives or olive oil in a diet has been proven to reduce the number of lipid peroxidation in the bloodstream. Olive oil can help blood vessels from clotting together. It is digested well by the stomach and has been proven to help ward off certain cancers. It also helps bone health and has been used by people with memory issues and has shown that it does help. The fatty acids are also great for the skin as they nourish it well. Key Takeaways:
"The antioxidant and anti-inflammatory properties of olives provide protection against cancer since chronic oxidative stress and chronic inflammation are the key factors in the development of cancer." Read more: https://news.statetimes.in/olive-oil-healthy-heart-2/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5062) The importance of consuming foods high in Magnesium
Date:
June 12, 2017 04:14 PM
It is important to consume foods that are very high in magnesium. Magnesium is very important to our overall health and functioning. It will help people with their biological functions and optimal health. The lack of magnesium can trigger very serious health problems. Magnesium plays a vital role in your body's detoxification process. You can increase your oxidation capacity in two ways. There is a certain amount of magnesium that your body needs every day. Key Takeaways:
"Magnesium is vitally important for biological function and optimal health." Read more: https://www.healthnutnews.com/the-importance-of-consuming-foods-high-in-magnesium/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4820) Omega 3 Fatty Acid Found To Stop Liver Damage From Getting Worse
Date:
April 27, 2017 11:44 AM
Oregon State University researchers have determined an Omega 3 fatty acid can stop the progression of liver damage in lab animals for specific type of liver disease known a nonalcoholic steatohepatitis or NASH. The Omega 3 which produces this effect is docosahexaenoic acid or (DHA) a readily available dietary supplement. However, researchers caution this treatment will most generally be used clinically since the population rarely follows dietary recommendations on supplements. NASH is caused from consumption of the western diet high in sugar, cholesterol and fats and can lead to the development of liver cancer or cirrhosis. Key Takeaways:
"Characterised by liver inflammation, oxidative stress and fibrosis, NASH is a substantial risk factor for cirrhosis and liver cancer." Read more: http://www.news18.com/news/health-and-fitness/omega-3-fatty-acid-found-to-stop-liver-damage-from-getting-worse-1378455.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4490) How antioxidants aid in healthy living: Vitamins C, E and beta carotene can help ward off a ...
Date:
March 04, 2017 02:59 PM
When it comes to boosting antioxidant intake, recent research indicates there's little benefit from taking diet supplements. A better way, according to a report in the September issue of Mayo Clinic Health Letter, is eating a diet rich in antioxidant-containing foods. Antioxidants such as vitamins C and E, carotene, lycopene, lutein and many other substances may play a role in helping to prevent diseases such as cancer, cardiovascular disease, Alzheimer's disease and macular degeneration. Key Takeaways:
"Antioxidants are everywhere. Energy drinks, skin treatments, vitamin supplements, and cold remedies, and all extol the virtues of their special combination of health giving ingredients." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4072) Importance of Antioxidants and How Can We Get Them from Various Foods
Date:
December 18, 2015 04:29 AM
Antioxidants, also known as anti-oxidation agents, are nutrients that help reduce the harmful effects of oxidants in the body. We all know that our body cells need oxygen for energy and growth. As our body cells use oxygen to create energy and sustain life, free radicals are released in the process as a byproduct. Antioxidants help combat the damage caused by oxidation. If you have ever left a slice of apple in open air, you must have seen that after some time the flesh of the fruit turns brown. This is a result of oxidation. However, if you apply a little lemon juice on the slice, and then leave it in open air, the apple slice will remain white. This is because of the antioxidant present in lemon juice. Similarly, the antioxidants present in the food we consume do the same thing, neutralizes the free radicals, and thus keeps our cells protected. Studies have proven that people who consume antioxidant-rich food are at lower risk of developing many diseases, including cancer. Thus, it is very important for you to include these important nutrients in your everyday diet. Foods Rich in AntioxidantsThese important nutrients exist in many foods, and you can easily get them through a well-balanced diet. Nutrients having antioxidant benefits include vitamin C, vitamin E, selenium, beta-carotene, and manganese. A large group of phytochemicals also works as antioxidants.
One of the richest sources of vitamin C is sweet red peppers, and one single cup of these peppers can provide you 190 mg or 200 percent of your required daily intake. You can enjoy 100 percent of your daily intake from a single cup of green peppers, orange juice, Brussels sprouts, and broccoli. One cup serving of cauliflower, cantaloupe, tomatoes, grapefruit, blackberries, and raspberries offers 32 percent of women’s and 25 percent of men’s suggested daily intake.
The richest source of vitamin E includes hazelnuts, almonds, sunflower seeds, pinto beans, peanuts, and vegetable oils like canola, corn, and safflower oil. 1 cup of cooked beans, 1-tablespoon vegetable oil and a one-ounce serving of seeds and nuts, offers 2 – 7 mg of vitamin E. These make 13 to 47 percent of your suggested daily intake. Certain vitamin C rich foods also fulfill 10 percent of your daily-required intake of vitamin E including blackberries, raspberries, broccoli, tomatoes, and sweet peppers.
Phytochemical antioxidants like carotenoids, resveratrol, and flavonoids can easily be identified because of the pigments they offer to the vegetables and fruits, like orange, red, yellow, purple and blue colors. Purple and dark blue fruits include blackberries, blueberries and grapes, and these are rich in resveratrol. Carrots, pumpkin, tomatoes, oranges, and red peppers are rich in carotenoids, which offer them a shade of red, orange, and yellow. Dark greens, particularly leafy greens, are rich sources of antioxidants, but the presence of green chlorophyll hides the other colors.
Dark chocolates are rich in flavonoids, but to enjoy the benefits you need to opt for those that have cacao solids. Milk chocolates and white chocolates do not offer flavonoids. Wine, tea, and coffee are also sources of flavonoids. You can find selenium in beans, nuts, and animal products like milk, beef, pork, chicken, and fish. The best sources of manganese are nuts, pineapple, beans, sweet potatoes, and brown rice. References //www.buzzle.com/articles/antioxidant-rich-foods-list-of-antioxidants-in-food.html //healthyeating.sfgate.com/natural-sources-antioxidants-8024.html //www.buzzle.com/articles/antioxidants-how-they-work.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3236) Vitamins that Help Balance Uric Acid in the Body
Date:
February 10, 2015 05:58 PM
What is a uric acid?
Uric acid is a waste product that can found in the body. It is a by-product of fructose metabolism. Therefore, a person with a diet rich in fructose will have a higher level of uric acid unless they can take certain measures to ensure that the levels are checked.
Effect of high uric acid
Very high levels of this waste product are associated with certain painful conditions. One of these conditions is gout. Gout is a type of very painful arthritis that will commonly affect the big toe. It is characterized by extreme pain and most people who have this condition are often on medication to regulate it for most of their lives. It is the most common disease associated with high uric levels, but not the only one.
People with High Blood pressure and obesity also exhibit higher levels of the acid in their systems. It is important to note however, that uric acid functions as both an anti-oxidant as well as a pro-oxidant. For this reason, you do not want to lower its levels too much, so as not to miss its anti-oxidation properties. You want to have optimal levels of the acid in your body and the following vitamins and natural spices can help you achieve this easily.
Vitamins to Regulate Uric Acid
Vitamin C: Vitamin C has been recommended in many health advice articles as being especially useful to lowering the levels of uric acid in your body. However, it is important to be very careful when taking Vitamin C for this purpose since taking too much could have the opposite effect; that of increasing the levels of this acid in your body. Vitamin C can be found in many natural supplements but you are likely to get good results with the natural sources, which are fruits such as oranges and lemons as well as in vegetables.
Vitamin B5: This vitamin is very important in breaking down excess uric acid in the body. Also known as pantothenic acid, it is actually the necessary ingredient in the body for the excretion of this acid. Most people who have excess uric acid have a Vitamin B5 deficiency. Stress is a major cause of low levels of this vitamin.
Vitamin B9: Also known as folic acid, this vitamin has been used by many people suffering from gout to help lower the levels of uric acid in the cells. Although there are no real studies that show its efficiency, many people who take folic acid supplements have claimed a reduction in the intensity of gout symptoms.
Natural Herbs and Spices that can help, there are also a number of natural herbs and spices that can greatly help to reduce the levels of uric acid in the body. This is because certain herbs have been known to have higher anti-oxidation properties than even fresh fruit and vegetables. Some of the herbs and spices associated with uric acid control include; cloves, ginger, rosemary and turmeric. These four spices also have anti-inflammatory properties that can be very useful to those suffering from gout.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3167) Can Guggle Extract Improve Bile And Fat Metabolism?
Date:
May 05, 2014 08:13 PM
Guggul extract on weight loss It is good to maintain a healthy lifestyle. If you do not do so, falling prey to a number of health complications is inevitable. Among the causes of these complications, fats metabolism happens to play a big part. There are numerous ways to help deal with problems associated with fat metabolism; guggle extract is one of them. A plant found in Asia and North African parts is widely used in weight loss programs. Its bark contains some sap that is extracted to offer the desired product. Many people are asking questions on how this extract helps improve both bile and fat metabolism. How effective guggul extract The sap obtained is also referred to us gum guggle or rather guggglesterones. These plant steroids are responsible for the positive effects the herb on the body fat metabolism. How does it help reduce cholesterol? It simply prompts an increase in the functioning of the thyroid. Biologically, this helps enhance metabolism. It occurs because food digestion is improved while at the same time the conversion of carbohydrates to fats is inhibited thus reducing cholesterol levels in blood. Perhaps that is why it is used in most weight loss programs. Other health benefits of guggle extract Furthermore, guggle extract improves bile functioning due to its cholesterol reduction characteristics. It kills two birds with one stone. As seen earlier, it inhibits formation of cholesterol on blood. Second, it helps in the excretion cholesterol from the body system. It is able to do this effectively due to the presence of phytochemicals. They inhibit farnesoid X receptor, which happens to be the bile acid receptor responsible for cholesterol levels in the body. It even blocks oxidation of low-density lipo-proteins thus enabling the breakdown of cholesterol into manageable compounds. Finally, there is no doubt on if guggle extracts helps improve bile and fat metabolism. There may be a few people who question its effectiveness, but numerous studies have cemented the truthfulness of the idea. This herb also has other uses thus check out for our next article to understand more about it. Source
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3112) Supplements That Can Improve Focus
Date:
March 23, 2014 07:57 AM
About focus A focused mind is one that is able to concentrate on a particular issue and think about it, discuss it or deal with it and pay special attention to that subject. This explains why people have different focus abilities as brought about by their varying environments and capabilities. Enhanced minds quickly grasp ideas as opposed to low minded ones. A determined mind therefore understands and interpret facts more readily in an effective way, and this is why it is important for individuals to to be focused at school. However, there are instances where learners have limited focus abilities, but this can be improved by use of focus supplements. The following are the supplements that can be used to boost an individual's focus levels. Supplement that can help improve focus
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3074) The Health Benefits OF Avocado Oil
Date:
March 08, 2014 09:02 AM
Benefits of avocado Avocado oil has a high attention of healthier fats and supplement E, that is a fabulous epidermis lotion. Icy pressed virgin avocado oil, taken consistently, may help decrease levels of cholesterol and ensure against coronary illness. Actually avocado oil holds its own particular emulsifier, lecithin, and additionally the cancer prevention agents Vitamin An and Vitamin E that likewise help to administer a young looking skin. These cell reinforcement vitamins annihilate the free radicals that execute your skin cells and make you look more advanced in years. Avocado oil can help you to continue looking more youthful as you develop sequentially more senior. It likewise holds vitamin D that is so paramount in large portions of the natural methodologies inside your skin - it is not called the 'daylight vitamin' to no end.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3052) Is Cocoa Butter Good For The Skin? Why?
Date:
March 06, 2014 03:27 PM
Cocoa butter Doubtlessly, there are few preferred healthy skin items over cocoa butter and some few that likewise makes you feel great deductively notwithstanding feeling extraordinary because of the way your skin looks so great, but Cocoa butter is good solid skin reinforcement, and for additional data on characteristic healthy skin items with a great experimental foundation. Therefore it is good for the skin. Reasons to why cocoa butter is good for your skin: Powdered cocoa butter contains a lot of diverse antioxidants which behave synergistically presenting a massive bothersome resistant to the cost-free radicals which eliminate your skin layer cells along with lead to quick getting older. Therefore, therefore, is it doesn't suitable natural skin care solution. Let's have a look at which record again. Precisely why your 'ideal' natural skin care solution? In order to solution which question, we need to have a look at precisely what antioxidants tend to be, along with precisely what hot cocoa butter can perform them, along with after that the reason why it is advisable than additional natural skin care merchandise on the market. Totally free radicals tend to be small substances kinds in the body's fat burning capacity while vitality is generated coming from blood sugar in the mitochondria of each and every cell phone within your body. Fortunately they are shaped simply by experience of toxins including pesticides, along with particularly the several poisonous pieces of cigarette light up. Cigars along with water lines tend to be believe it or not harmful than tobacco, along with filtration system guidelines make not any difference towards the production connected with cost-free radicals. What exactly that they do is always to eliminate cells, when they're pores and skin cells you continue to grow older. Your skin layer wrinkles along with dries up, and you begin to take on the style connected with an individual many years over the age of you're. These people try this by way of a procedure often known as oxidation, along with antioxidants can certainly keep the idea. These people reduce the effects of your cost-free radicals, and forestall your skin layer cells coming from getting ruined. Contents of cocoa Powdered cocoa butter contains several different antioxidants that can eliminate away from numerous diverse cost-free radicals along with superoxides, as well as hydrogen peroxide. Vitamin e is really a powerful antioxidant -- your strongest of all the so-called antioxidant vitamin supplements in fact, and will quickly eliminate away from hydrogen peroxide along with any oxidizing agent. Others tend to be vitamin supplements A new along with G, however they can not strategy the potency of vitamin E. Furthermore, it contains phytochemicals (posh title pertaining to place chemicals) including flavanoids which might be also powerful antioxidants. Polyphenols are very effective in neutralizing cost-free radicals, and the hot chocolate mass polyphenols tend to be in particular successful. In fact, hot chocolate butter boasts a greater antioxidant awareness and then possibly blueberries as well as other so-called superfoods. In order that hot cocoa butter to work, it will email numerous of the pores and skin cells as is possible, that involves do away with the idea properly directly into your skin layer. The epidermis is incredibly absorbent all of which will eliminate cost-free radicals in the reduced absolute depths of the pores and skin as soon as they're created, along with ahead of they are able to do injury. It is clinically demonstrated which hot chocolate butter will certainly keep pores and skin degradation a result of the harmful consequences from the UV light in the rays of the sun -- UV rays builds cost-free radicals which are very effective in doing damage to pores and skin. Merely go through the influence connected with sunburn! However, there is additional in order to hot chocolate butter than which. It contains a substantial percentage connected with vitamins as well as lime scale, potassium, magnesium, zinc, manganese, copper along with metal, all of which come in a highly bioavailable style which make them far better which business vitamins. Not just that, though. Furthermore, it contains tryptophan, involved in the development connected with serotonin, your 'feel good' neurotransmitter, and also dopamine along with phenylethylamine, many beneficial materials. It is a mental faculties food as well as food to your pores and skin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3049) Are Pumpkin Seeds Healthy For Men and Women?
Date:
February 04, 2014 06:45 PM
Pumpkin seed Pumpkin seeds have been gaining traction around health circles in recent months and all for the right reasons. These greenish flat-shelled seeds that pumpkin lovers have been throwing away for years have been proven through tests to contain a whole lot of nutrients. 1. magnesium According to www.whfoods.com, tests showed improved insulin regulation helping reduce prevalence of diabetes thanks to the various unique protein types in pumpkin seeds Pumpkin seeds are rich in omega 3 fats that help prevent BPH - Benign Prostatic Hypertrophy a condition where the prostrate gland becomes enlarged.They also contain cancer-fighting compounds known as cucurbitacins that kill cancer cells.According to www.health.yahoo.net , recent research has shown that eating pumpkin seeds lowered risk of breast cancer in post menopausal women by 23%. Pumpkin seeds contain tryptotophan that converts various amino-acids to serotonin which is known to improve sleep and lower depression Thanks to the zinc, manganese and various types of Vitamin E, pumpkin seeds are also great anti-oxidants for the body for both men and women of all ages. According to www.healthyeating.sfgate.com, pumpkin seeds improve blood flow in the body by thinning blood due to its vitamin E elements and also helps in blood clotting and bone development due to vitamin K. 1. Rich in magnesium which aids in heart-related ailments
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3002) Astaxanthin Protects The Eye And More!
Date:
November 13, 2013 02:52 PM
Astaxanthin is a carotenoid that is commonly found in the marine environment. It is naturally found in salmon, krill, trout, crayfish, shrimp, crustaceans and yeast. It is the chemical that is responsible for the red color in cooked shellfish and salmon meat. The algae Haematoccus has the richest natural source of astaxanthin. Astaxanthin can also be produced synthetically, but due to the synthetic product consisting of different steriosmers it is not preferred to be used in some cases. Unlike beta-carotene it has two more oxygenated groups on each of its ring structure, these additional functional groups make it a highly potent antioxidant and give it a configuration that is more polar than that of other carotenoids. Vitamin E has been known as the strongest antioxidant both in topical use in cosmetics and in internal use, but research has shown that astaxanthin has a greater antioxidant strength than Vitamin E. For example in the quenching of singlet oxygen it has an antioxidant strength five hundred times stronger than Vitamin E. Unlike many other antioxidants it has the ability of crossing the blood-brain barrier and enter into the eyes, brain and central nervous system (CNS). Most diseases of the CNS and eye are caused by increased generation of free radicals or by a decrease in the ability to remove free radicals from the body. Some of the diseases that are caused by problems with inflammation and oxidation include Glaucoma, Cataracts, and Huntington’s disease. These can be prevented by taking astaxanthin. It has anti-inflammatory properties that are related to its strong antioxidants properties. It suppresses some of the inflammatory mediators such as, prostaglandin E-2 (PGE-2), tumor necrosis factor –alpha (TNF-a), and nitric oxide. Unlike other anti-inflammatory drugs like acetaminophen that can damage the liver and aspirin that may cause stomach bleeding, astaxanthin doesn’t have any side effects. In people suffering from rheumatoid arthritis and carpal tunnel syndrome it has the ability of reducing pain. Studies have shown that it is able to reduce pain in rheumatoid arthritis by 40% after 8 weeks of continuous use. It prevents Ultra Violet induces oxidative stress of the skin and prevents the photo aging of the skin. It prevents UV induced formation of wrinkles and collagen degradation in the skin. It may be applied on the skin or taken orally. In people participating in sports it eliminates the soreness of joints after exercise, and reduces the pain caused by inflammation. This enables athletes to train harder and as a result increase their endurance, skill, and strength. This is through its ant-inflammatory and ant-oxidant effects in the mitochondria (energy producing organelle). It strengthens the immune system, research by scientists has shown that it causes increase in production of T cells, stimulates the proliferation of lymphocytes, amplify the cytotoxicity of natural killer cells, decrease damage of DNA, and increases significantly delayed type hypersensitivity syndrome. It prevents heart disease and reduces the risk of people already suffering from heart disease form getting a stroke or heart attack. It improves the blood lipid profiles by increasing HDL (high density lipoprotein) and decreasing LDL (low density lipoprotein). The liver main function of the liver and kidney is the detoxification and removal of harmful substances in the body. These activities lead to the formation of free radicals. Astaxanthin being a strong antioxidant helps by destroying these free radicals hence it eliminates their oxidative effects. As a result of its immune benefits Astaxanthin also has anti-tumor properties and as a result it prevents the development of cancer. Its prevention of cancer is also caused by its antioxidant properties and by it regulating gene expression.
References 1. //www.peakhealthadvocate.com/2826/astaxanthin-benefits-include-eye-heart-health/ 2. //articles.mercola.com/sites/articles/archive/2013/02/10/cysewki-discloses-astaxanthin-benefits.aspx 3. //www.lef.org/magazine/mag2013/apr2013_Astaxanthin-Provides-Broad-Spectrum-Protection_01.htm 4. //www.vitguide.com/astaxanthin-benefits/ 5. //www.greenmedinfo.com/blog/astaxanthin-supercharged-health-benefits
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2890) How Does Chlorella Improve Your Health?
Date:
November 04, 2013 05:06 AM
What is Chlorella Chlorella is made by two cycle periods that determine the total cell size and length. A timer usually runs through the G1 phase and it leads to the cell attainment prior to S phase without further growth requirement. The cycle is consistent with increments of size control. It multiplies rapidly through photosynthesis and requires only three basic conditions to reproduce namely; water, carbon dioxide and sunlight. There are various health benefits of chlorella including; Vitamins Chlorella is rich in various types of vitamins including; A, B1, B2, B6, B12, C and E. It provides the nutrients as a whole food bundle that is way superior than manufactured formula. Minerals Chlorella is rich in magnesium that helps in improving blood sugar levels, mental health and heart health. It also contains other rich minerals including; iron, potassium and calcium. Amino Acids Chlorella is a rich protein source and it also contains important amino acids. The amino acids are used by the body for rebuilding neurotransmitters and lean tissues. Detoxification Chlorella is very effective in binding with toxic chemicals and heavy metals. The toxins are removed from the body hence bringing a positive health impact. Energy Chlorella increases the body energy. It is also very effective in elevating moods and it is way stronger than taking super food. Cancer Chlorella has amazing cancer-fighting abilities due its rich natural carotenoids that prevent oxidation. It also has the ability to nourish the system. Diabetes Chlollera helps to improve blood sugar levels and insulin over time. It can also improve insulin resistance and diabetes. Heart Disease Chlollera offers protection against heart disease by improving LDL cholesterol and triglyceride. It also has strong antioxidant properties. Obesity Chlollera has unique properties that can lower body fat. It can also improve insulin sensitivity and aid fat metabolism. Reference: www.jstor.org, www.naturalnews.com
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2874) What Is Ubiquinol?
Date:
August 23, 2013 02:54 PM
Coenzyme Q10 (Co10) is a naturally-occurring chemical compound in the body which fuels cell growth and enhances enzyme functions. It exists in three forms; ubiquinone (fully oxidized), semiquinone (partially reduced), and ubiquinol (fully reduced). So, ubiquinol is basically a reduced form of Co10, it is a strong antioxidant that can neutralize free radicals. Free radicals refer to a reactive and unstable atom that can trigger many medical conditions such as cardiovascular issues, weak immunity and even cancer.
Ubiquinol is found in almost every organ, tissue and cell in mammals. This lipid-soluble benzoquinol can be acquired through supplementation, biosynthesis and from diet (in small amounts). Ubiquinol plays an integral role in transferring electrons within the body, thereby leading to ATP synthesis. The antioxidant property of ubiquinol is very essential in the functioning of the cellular systems.
Ubiquinone is naturally converted into ubiquinol by the body to produce energy for the cells. The failure of this process can lead to insufficient energy levels in the body. The ability of the body to generate Coenzyme Q10 reduces with age and so does the ability to convert ubiquinone into ubiquinol. Therefore, older people should use ubiquinol supplements to boost their energy levels. Apart from older people, those who suffer from neurological, cardiovascular, diabetes and liver conditions may also have low ubiquinol levels.
There are many health benefits associated with ubiquinol. First, it offers a sufficient amount of energy which the heart needs to work well. It's also a strong antioxidant that protects the heart, and other vital body organs from free radicals. When it comes to energy, ubiquinol is an essential component in 95 percent of the energy produced in the body. Daily intake of ubiquinol supplement can help reduce fatigue and muscle pains; the common symptoms of insufficient Coenzyme Q10 in the body. Since ubiquinol is a strong fat soluble antioxidant, it can protect the body from oxidation, thereby providing an anti-aging benefit. Do you feel fatigued, run down with no energy? Consider Ubiquinol as a natural safe energy boosting supplement.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2850) What is Monk Fruit And Why Is It Healthy?
Date:
July 24, 2013 10:24 AM
Monk fruit also known as luo han guo is a green melon cultivated in central Asia. It has been cultivated for many years by the Buddhist monks. The fruit contains an intensely sweet compound known as mogroside. It is a healthy, natural alternative to sugars and artificial sweeteners. The fruit is extracted in order to get mogroside which is many times sweeter than sugar. Monk fruit is crushed, combined with water, filtered and spray-dried to produce a sweet-zero-calorie powder known as fruit-sweetness. This sugar is used in several foods and beverages. Health benefits Ancient Chinese and Buddhist used monk fruit as treatment for various ailments, such as constipation, sunstroke and coughing. Modern research shows that mogroside can be used to treat diabetes since it contains a low glycemic index and can stimulate insulin secretion. In china, monk fruit was also used for many years to treat obesity and diabetes. The fruit contains antioxidants with anti- inflammatory benefits. British Journal of Nutrition reported that use of monk fruit by animals showed a reduction in lipid peroxidation or cell damage as well as urinary albumin levels. This shows that it protects kidneys from diabetic damage. Monk fruit strengthens the immune system, digestive tract, respiratory system as well as glands. This fruit is capable of eliminating and defending people against various health-related issues. The fruit reduces cholesterol, triglycerides and improve liver function. Furthermore, it increases good cholesterol while protecting the liver. It prevents cholesterol oxidization (due to its antioxidant potential) this results to reduced risk of heart diseases and strokes. Monk fruit extract has an antihistamine effect. The extract tends to counter an allergic response by soothing the mast cells that produces chemicals such as histamine. This chemical is related to both allergies and asthma. It is considered one of the best non-sugar sweeteners. It is combined with supplements used to promote and maintain a healthy weight.
Reference
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2849) Why Is Acai, Goji, Pomegranate, Noni And Mangosteen Called Super Fruits?
Date:
January 15, 2013 04:55 PM
Health Benefits Of Super Fruits "Super fruits" is an idiom that is frequently used to refer fruits that have extraordinary antioxidant and nutrient qualities and provides benefits over and above the basic nutrition. Exotic fruits such as acai berries, goji berries, mangosteen, noni and pomegranate have earned this distinguished status. These fruits have exceptional amounts of vitamins, antioxidants and phytochemicals that play a significant role in preventing various diseases. Each of these super fruits restrains its own distinctive set of properties that prove to be extremely beneficial for the overall health of the body. Health Benefits Associated With Super Fruits: Acai Berry: Acai berry is a rich source of dietary fiber, protein and a compound called anthocyanins. It also includes high levels of omega-6 as well as omega-9 fatty acids, which are believed to have a protective effect on the cardiovascular system and heart. In addition, the anthocyanins compound present in the acai berry helps in lowering the blood cholesterol level. Mangosteen: This fruit is abundantly grown in south Asian and due to its fine flavor it is also referred to as "The Queen of Fruits". Mangosteen retains high levels of phytochemicals known as xanthones that offer this fruit a unique medicinal property which is not found in other common fruits. Mangosteen also includes other powerful natural compounds such as polysaccharides, catechins, quinones, polyphenols and stilbenes. Each of these compounds are believed to be effectual in preventing diseases such as, osteoporosis, atherosclerosis, high blood pressure, kidney stones, glaucoma, cataract, Alzheimer's, neuralgia etc. The fruit is also used to treat aging, depression, obesity, allergies, skin diseases, ulcers, fevers, diarrhea and pain. Noni: Noni juice is known to restrain more than 150 nutrients, including protein, all the essential amino acids, vitamins A, B1, B2, B3, C and E, minerals such as iron, calcium, magnesium, selenium and potassium, polysaccharides, phytonutrients and digestive enzymes. Noni is one of the most unique super fruits. Noni juice can help to normalize blood sugar levels; decrease inflammation, arthritis and joint pain; enhance digestive function, cleanse colon, remove parasites; reduce irritable bowel syndrome, diarrhea, constipation and menstrual cramps; prevents gastric ulcers; relives pain, mental depression and atherosclerosis. Goji Berry Juice: This miraculous berry is rich in polysaccharides. It also includes fiber, 18 amino acids, 21 minerals, Vitamins A, C, B, & E, protein and Omega-3 and Omega-6 fatty acids. Goji juice is a potent antioxidant that prevents premature aging. It also stabilizes molecules called free radicals that damage the DNA and gives rise to several diseases. Moreover, Goji juice helps in reducing the risk of cancer by averting DNA mutation, curtailing growth of tumors and by managing the peroxidation of lipids. This distinctive fruit helps to relieve insomnia and headache, improve functions of the heart, assist in digestion, aid to regulate weight, promote sexual health, improve fertility, enhance memory functions, and alleviate dry cough. Pomegranate: Pomegranate is one of the oldest known super fruits. It is rich in vitamins A, B and C, potassium, magnesium, phosphorous, calcium and sodium. Pomegranates are very high in dietary fiber which boosts the digestive system. Additionally, medical evidences reveal that a unique amalgamation of polyphenols found in pomegranate helps to lower LDL or bad cholesterol in the blood which eventually benefits the heart. Moreover, pomegranate's natural antioxidant and anti-inflammatory properties aid to slow down the development of cancer especially, prostate and lung cancer. Overall, super fruits are extremely valuable for our body due to its high anti-oxidant and nutrient content that helps to reinforce the body's natural defenses and make it healthier and less prone to most type of diseases.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2812) Camellia Sinesis
Date:
November 22, 2012 11:03 AM
Black Tea Among beverages, many varieties of tea exist including oolong, green and black tea. they are in fact quite similar in their natural state and chemical composition. However, the benefits of black tea extract has begun proving its mettle after the rather heavy overdose of information and research on green tea. The important ingredient that has made tea a rage in alternative medicines in the modern times is the contents of polyphenol which is beneficial in reducing fat absorption and aiding weight loss. In fact, while green tea extract has about 30-40% of water soluble polyphenol, black tea has about 10% . Benefits: What has however been proven through recent clinical studies is that the four kinds of polyphenols found in black tea extract are more active on adipose tissue mass, liver lipid content thereby suppressing body weight more effectively as compared to green tea. Green tea is the fresh plucked leaves of the camellia sinesis plant while black tea extract is made from the fermented leaves. While the green tea leaves are only lightly dried, black tea leaves are fully oxidized. Both contain flavonoids known for their beneficial effects on the human body . However because of the excessive oxidation in black tea, the flavonoids convert to complex theaflavins and thearubiglins.These are antioxidant known to be tremendously potent in effectively countering cancers, stroke and heart ailments. Potent Health Benefits *Its proven to affect on triglycerides present in the blood thus affecting body weight issues dramatically. In fact clinical observations have proved that it induces reduced levels of cholesterol with no side effects on fat soluble vitamins. It's safe usage could not have been proved better:
An intake up to three cups is said to have beneficial effect but again discretion should be maintained in cases of hypertension, blood pressure and anxiety, who could do without the effect black tea extract has on blood circulation and heightening of alertness.Without a doubt black tea extract remains one of the most common proven natural formulas with great benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2732) Niacin And Niacinamide?
Date:
November 18, 2012 10:32 AM
Niacin Vs Niacinamide Niacin Niacin also known as nicotinic acid is an organic compound and it is one of the essential human nutrients. Niacin deficiency can result to pellagra. It is also used for reducing cardiovascular issues. A chemist called Hugo Weidel first described niacin in 1873 in his studies of nicotine in the oxidation of nicotine using nitric acid. The name niacin was derived from nicotinic acid + vitamin. Niacinamide Niacinamide is also known as nicotinamide or nicotinic acid amide. It is the amide of niacin. Niacianamide is part of B-vitamin and it is water soluble. Niacinamide is derived from niacin. These two are components of B3-vitamin and they are often used as supplements interchangeably. However, there are some critical differences between these two vitamin B3 components. Niacinamide is derived from niacin and the body is able to convert niacin into niacinamide. Niacinamide can also be made by our body from an amino acid known as trytophan which is usually present in animal foods. A chemical compound known as an amide is what makes niacinamide. Amide is defined by a nitrogen atom which is combined with a carbonyl group or C=O. Therefore, the main distinction between these two components is that niacinamide is a derivative of niacin. Different Pharmacological Properties Although the two are used interchangeably, they have different pharmacological properties. Their physical effects on the body also differ and people who are sensitive to their effects may prefer to use one over the other. Their usefulness in treating different conditions for instance high cholesterol, circulatory problem and osteoarthritis can also differ. Because of the pharmacological properties difference in niacin and niacinamide, different people can have different physical reactions when they take one as opposed to the other. High niacin doses can cause flushing a condition that causes blood vessels to widen. This makes the capillaries under the skin to expand to allow more blood to flow making the skin to become red and itchy. Niacinamide does not have the effect of skin flushing and that is why it is preferred over niacin in the treatment of pellagra, a condition that results due to lack of vitamin B3. The only affect that niacinamide may cause is excessive sweating. Niacin And Cholesterol Niacin on the other hand it is preferred in the treatment of high cholesterol levels while niacinamide is not preferred in this treatment. This is because since niacinamide is a derivative of niacin, the cholesterol lowering properties in niacinamide are inhibited. Niacin is also preferred in treating circulatory problems because of its effects on the blood vessels and the role it plays in lowering high cholesterol levels hence preventing hardening of the arteries. This in addition reduces the risk of heart attacks. On the other hand, Niacinamide may also be preferred for treating osteoarthritis and diabetes. The two can be used in treating physical and emotional stress. Either niacin or niacinamide may be used for treating anxiety and depression. For these two components of Vitamin B3 to be effective, doctors recommend that they ought to be taken in combination with Vitamin B1, B2 and C.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2721) Grape Seed Extract
Date:
November 13, 2012 07:58 AM
Grape seed extract ( also known as vitis viniferal) is a substance derived or sourced by manufacturers and industries from whole grape seeds. Grape seed extract was discovered in the Ancient Greece and many parts or sections of the grape were commonly used for different medicinal purposes. Its Contents: Grape seeds have a high concentration of Vitamin E, linoleic acid, Flavonoids and Opcs. Its health benefits. Its said to help protect the body against cancer. Studies done by scientists in laboratories have demonstrated that grape seed can actually help fight and protect against the free Radicals attacks in the body ( Radical attacks are Chemical by products which are known to lead or cause damage to the DNA of the body thus leading to cancer). Grapeseed extract and Diabetes According to a 2009 study on 32 type 2 diabetic subjects at high cardiovascular risk, it was seen that extract played a significant therapeutic role or part in decreasing cardiovascular risks.The grape seed extract greatly improved the markers of glycemia and inflammation which showed that the grape seed extract helped in decreasing cardiovascular risks in the type 2 diabetic patients.It is also known to help in eye diseases related to diabetes. Heart Disease: Still in 2009, a study done on patients with a Metabolic syndrome revealed that the extract significantly lowered the chances of having type 2 diabetes and developing a heart disease. It can also help in a type of poor circulation called 'chronic venous insufficiency'. In addition it helps in high cholesterol conditions, it reduces swelling caused in injuries. The primary cause for aging is 'oxidative stress' which is normally caused by free Radical attacks (Mentioned earlier). To protect against Oxidation the body needs Vitamin E and C, the extract contains a high concentration of Vitamin E which helps curb oxidation. Grape seed extract (as noted earlier) also helps in fighting the free Radicals that cause oxidation thus slowing down the aging process.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2713) C and Bioflavonoids
Date:
October 31, 2012 04:47 PM
A supplement of super bio C vitamin is essential to the body because of the unique properties it possesses. Taking this supplement will enable a person reap the full benefit of a normal vitamin C compound without experiencing side effects normally associated with common Vitamin C sources. Such side effects include excessive acidity in the stomach. Additionally, intake of C vitamin has been found to have immense benefit to the health of the human body. It performs some core functions such as detoxification of the body and boosting the immune system. Also people who are nursing injuries will find this Vitamin helpful as it accelerates the healing process through its ability to repair tissues fast. Bioflavonoids Bioflavonoids on the other hand, are plant compounds which occur naturally. They are popular for their antioxidant properties. Recent studies show that Bioflavonoids play an even greater role in preventing elimination of vitamin C from the body. Therefore they are helpful as they protect Vitamin C from complete oxidation. This means that the human body will benefit by having vitamin C retained longer. A combination of these two compounds helps to promote better health of a person. Some benefits include improved eyesight, better cardiovascular health and an improvement in the structure of the connective tissues. They also help to improve the skin appearance through its replenishing and nourishing properties. Further to this, combination of vitamin C and Bioflavonoids can go a long way to lower the effect of some common but serious diseases such as cancer and gastrointestinal disorders. More so, Arthritis and atherosclerosis are among the diseases that can be prevented by intake of the compounds mentioned. Research shows that intake of both vitamin C and Bioflavonoids alleviates allergies and inflammation in the body. It can also help the body fight Colds and other respiratory infections. have you had your bio C today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2698) The benefits of the hawthorne berry
Date:
June 27, 2012 12:14 PM
It is in the autumn that the hawthorn flowers will give way to the red berries which are a very rich source of antioxidants and of course, flavonoids. The benefits of using them are numerous and most of the times people will get eat them because they can prevent the damage caused by free radicals, they will protect the blood vessels, they will stimulate the circulation and also strengthen the heart. The hawthorne berry benefits: Dilates blood vessels,Reduces LDL levels (bad cholesterol), Prevents damaging effects of free radicals, Strengthens the heart, Regulates the heart beat. Uses The main reason to why people are using hawthorn berries is because they have a lot of heart benefits. People who have heart problems will certainly have chest pains as well associated with them and these pains are one of the things that these berries can help with. People who have a high blood pressure will also respond positively most of the times when using these berries. Because these berries will improve the blood circulation, there is going to be less strain put on the heart. By using hawthorne berry preparations, the harmful plaque that forms around the arteries and blood vessels will be diminished. Mainly, this extract is going to help people in having the damaging LDL cholesterol in the body reduced. Antioxidants Hawthorn berry contains two main heart benefitting constituents and they are the OPCs and the flavonoids. They are both very rich in protective antioxidant properties, which will prevent the oxidation caused by the free radicals. This is not only going to be beneficial for the capillaries and heart, but also for the entire body. Benefits Flavonoids can easily dilate the blood vessel, strengthen them and also protect the entire blood vessel system in order to eventually increase the blood flow. People who are exposed to inflammatory agents or are suffering from inflammation, will be happy to know that the OPCs and the antioxidant properties of Hawthorne berries will help them in this regard. For instance, the astringent hawthorn preparations can be used externally in order to soothe skin irritations, bug bites, minor cuts and acne. On top of that, using the extracts created from hawthorn berries will strengthen the heart and regulate the heartbeat. Preparations For those who want to prepare a tincture, they will only need to soak some Hawthorne berries in alcohol for several weeks. What this will do is draw out their properties and concentrate them in the alcohol. More to that, the berries can be made into syrups, jams and jellies. Most of the times though they are used to flavor brandy or into wine fusions. Also, tea made using the berries of hawthorn trees are the best for enjoying a great healthy state for the heart. History The preparations of hawthorn berries have a long history of use and mainly their benefits were concentrated in heart tonics. Dioscorides, a green herbalist from the I (first) century recorded that hawthorn was used back then as a strengthener and as a tonic. In the sixteenth century, Paracelsus, a Swiss physician reported that he used Hawthorne's cardio-tonic effects. A few centuries later, it was used by American doctors in order to treat circulatory and heart disorders. Even today, Hawthorne is used a lot and studied even more to unravel more of its beneficial secrets.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2660) Can L-Carnosine Be Used As An Anti-Aging Vitamins?
Date:
April 18, 2012 07:31 AM
Carnosine And Your Health Carnosine has gained widespread popularity as an anti-aging compound despite some skeptical voices in the scientific community. Many studies lend credence to its value for treating the signs of aging and its antioxidant properties are well researched. Carnosine is also widely used as a supplement to prevent complications from diabetes such as nerve and kidney damage. This article will discuss the details of what it is, what it seems to do in the body and how it may be able to help people restore a more youthful state of health. Discovered in Russia more than a century ago, Carnosine is an amino acid and is found primarily in muscle, skeletal and nervous tissue (including the brain). As such the primary dietary sources are animal products such as fish, poultry and red meat. It is common for vegetarians to become deficient in it, making them ideal users of carnosine supplements. Glycation There is a gradual decline in carnosine levels as we age, which lends credence to the claims of its anti-aging properties. The most clearly established property of carnosine is its ability to act as an anti-glycation agent. Glycation is a process the body goes through to release energy from sugar but which ends up producing harmful substances. Carnosine can neutralize some of these already formed substances and also prevent the process from forming new ones. Some researchers believe glycation may be the key behind the benefits of caloric restriction, making carnosine the long awaited magic pill that can mimic its effect as a longevity treatment without the deprivation of restricting food intake. Antioxidant Properties In addition to carnosine's anti-glycation effect, it also has antioxidant properties. The oxidation process which the body goes through naturally produces the well known "free radicals" which slowly damage the cells and are thought to play an important role in the aging process. Carnosine can neutralize this protecting the cells. This also has a beneficial effect at keeping the telomeres from shortening, which is thought to be the main cause of the aging process. Telomeres are the buffers at the ends of DNA code that protect the code from being corrupted, so when the telomeres become shorter there is less protection and a greater chance of things going wrong. This makes carnosine's protective benefits of great importance in the fight against aging. Carnosine Protects The Cells From Damage Like Radiation Studies show that carnosine can protect the cells from radiation damage, which is particularly useful for cancer patients who have to undergo radiological treatment. It also promotes the healing of wounds and protects cell membranes. Some studies demonstrate that it can literaly repair old cells and make them younger. As it binds easily to toxic metals, turning them into powerful antioxidants, it is very effective at protecting the body from their harmful impact. Some of the most promising uses of carnosine are for the treatment and prevention of Alzheimer, the signs of aging in the skin, cataract, nerve and kidney damage and heart disease. The recommendation for use as a supplement is 500 miligrams, though the body can deal safely with much larger doses. Give Carnosine a try today and experience the difference yourself.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2636) What Is L-Carnosine And What Does It Do?
Date:
March 30, 2012 08:28 AM
What Is L-Carnosine L-Carnosine is basically a combination of 2 vital amino acids-L-histidine and beta-alanine. It is naturally present in the body, mainly in the muscle, and in many animals too. Carnosine can be broken down easily into the two amino acids, but it is good to know that these amino acids work much better when combined to form L-Carnosine. L-Carnosine has the remarkable ability to revitalize, that is, to make older cells younger and lengthen their life cycle. This compound is commercially available and is the only one that has the rare and distinctive ability to rejuvenate cells. What does L-Carnosine do? In simple language, L-carnosine is able to transform itself into so many compounds with each performing or enhancing a number of crucial body functions such as: May bind to dangerous metal compounds to make them inactive. Turning the resultant metal compound/carnosine into useful antioxidants which in turn can be anti-ulcer agents Protecting and stabilizing cell membranes, keeping cells safe from dangerous free radicals Protecting healthy cells from damage caused by radiation Fighting allergies Enhances blood flow to the brain Acts like a neurotransmitter, helping messages move from one nerve to the other. This helps fight dementia, as in Alzheimer's disease and Parkinson's disease, and boost memory. Blocks guanylate cyclase activation, an enzyme associated with cancer, migraine, asthma, and septic shock. Special derivatives of carnosine can help get rid of the accumulation of sugar compounds and abnormal protein in the eye. A variety of these compounds may cause glaucoma, cataracts, and macular degeneration. Carnosine works like a catalyst to boost the work of so many other compounds and nutrients. Benefits of using L-carnosine Although L-carnosine benefits haven't been extensively researched, according to initial studies it may help in: Dealing with complications related to cataracts, diabetes, neuropathy, and kidney failure. It may also help in slowing down aging in skin, minimizing wrinkles as well as breakdown of elasticity in skin. It can help to prevent joint inflammation, atherosclerosis, and formation of cataract. Carnosine has been known to prevent and reduce cell damage occasioned by beta amyloid-the substance found in Alzheimer's patent's brain. Additionally, carnosine appears able to help get rid of the helicobacter pylori bacterium, the organism associated with stomach cancer and peptic cancer. Therefore, it can significantly help protect and heal both peptic and gastric ulcers. Other possible L-carnosine benefits Increase muscle endurance and strength Improves heart function Speeds healing of wound A powerful antioxidant that can deal with even the worst free radicals Reduces inflammation and boosts immunity It helps pull out or chelate some heavy metals from your body May help autistic children Act as anti-cancer agent in the body Stabilizes cell membranes and slows down lipid peroxidation to protect the process of aging of the brain L-carnosine can help in preventing or even treating age-related conditions like: Cell aging/cellular senescence Neurological degeneration Cross-linking of eye lens Build up of damaged proteins Brain circulatory deficit Muscle atrophy Cross-linking of collagen in the skin DNA chromosome damage LDL cholesterol oxidation Formation of AGEs i.e. advanced glycation end-products. What is stopping you from taking L-Carnosine today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2623) The Benefits of the Amazing Duo of CoQ10 and Red Yeast Rice
Date:
March 11, 2012 03:08 PM
What Is Cholesterol? Cholesterol is a substance produced by the liver that provides a number of benefits to the body. A problem occurs when the level of blood LDL or bad cholesterol goes beyond a normal level. High level of bad cholesterol in the body can inflict damage to the arteries during the process of oxidation which can lead to the heavy accumulation of stiffened fats and deposits in the walls of the arteries. This can constrict the arteries that eventually lead to a minimal flow of oxygen-rich blood to the heart and brain. Inadequate supply of blood to the heart and brain can trigger heart attack and stroke. When the kidney perceives an inadequacy in the supply of blood to the brain and heart, it produces substances that help in increasing the supply of blood to these organs. However, in effect, it also increases blood pressure. Many serious health complications emanate from abnormally high levels of bad cholesterol or low density lipoprotein (LDL) in the body. As people get older, their awareness about maintaining an optimum level of cholesterol should increase significantly. Undeniably, cardiovascular diseases that are triggered by high levels of cholesterol in the body have been one of the major causes of death worldwide. Red Yeast Rice Intake of red yeast rice is considered to be one of the most effective alternative ways to lower the level of cholesterol in the body. It is produced by fermenting a certain type of red yeast that is poured over the rice. Researchers believed that red yeast rice contains high levels of substance lovastatin that inhibits the production of enzyme HMG-CoA reductase which is responsible in regulating the production of cholesterol in the body. Red yeast rice actually contains sufficient amount of monacolin K and 8 more monacolin substances that are work like statin drugs in reducing the level of cholesterol. Basically, the substances prevent the liver from producing alarming level of bad cholesterol. Lowering Effects of LDL Red yeast rice is a great alternative choice for patients who are searching for non-prescription ways of lowering their cholesterol. A clinical study shows that red yeast rice can significantly lower the level of cholesterol in the body by as much as 20% without exposing the victim to the risk of suffering from muscle pain. Another study reveals that after taking 1800mg of RYR daily for 12 weeks, the users' bad cholesterol level have significantly drop by 27%. Red yeast rice is actually an FDA-recognized dietary supplement. It is renowned for its capacity to work similar to a statin drug that effectively drives the body to achieve an optimum level of cholesterol. A number of scientific studies revealed that intake of red yeast rice can significantly lower the levels of bad cholesterol and triglycerides in the body. Furthermore, studies show that continuous intake of red yeast rice can contribute a lot in improving the amount of total cholesterol. Together with red yeast rice, CoQ10 make an amazing duo in lowering the level of bad cholesterol in the body and promote overall cardiovascular health. Intake of CoQ10 is highly recommended to people who take red yeast rice because CoQ10 provides energy and strength to the heart when pumping blood to other organs. When used together, CoQ10 and red yeast rice can increase the transfer of oxygen and energy between the cells and the blood which leads to a significant reduction in the level of cholesterol produced.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2607) What Makes Ubiquinol The Best Form Of COQ10?
Date:
March 08, 2012 11:48 PM
Benefits of Ubiquinol Ubiquinol is an active antioxidant form of CoQ10. It is pre-converted and ready-to-use diet supplement. Hence, it is easily absorbed and utilized by the body. Research studies show that ubiquinol has proved to be much more effective than ubiquinone and has all vital health benefits as CoQ10. Ubiquinol is the next generation supplement which provides support for a healthy body and mind. It helps you to live a healthy life by raising your CoQ10 plasma level. It also plays an important role in production of energy levels. Moreover, it protects the cells of the body from oxidative kind of stress which can eventually damage proteins, DNA, and lipids. Benefits of Ubiquinol: Cardiovascular health: Clinical studies show that ubiquinol improves the overall cardiovascular health. Cardiac patients who have been taking high dosages of statins like Lipitor, Zocor, etc for a long period of time have decreased levels of coenzyme Q10 as these statins inhibit the body's production level of coenzyme Q10. The low levels of CoQ10 in the body can result in cardiomyalgia, fibromyalgia, atherosclerosis, etc. Thus, if these patients take ubiquinol which is an antioxidant then it neutralizes the oxidation of LDL. Cognitive Health: It helps to increase the stamina and energy and promotes general health and wellness. Anti-aging support: Due to degeneration and advanced age, the aged people have less CoQ10 biosynthesis and body's conversion ability also diminishes in such subjects. A collaborated study carried out on middle aged people demonstrated that subjects who were given this supplement showed marked improvement in their physical and mental activities. Thus ubiquinol by and large promotes life extension and improves the overall mental health by compensating for the age-related conversion disability. Power to other organs: Ubiquinol plays an important role in igniting energy levels within the cells of vital organs like heart, kidneys, liver, and lungs. Thus it naturally helps you to sustain your energy levels. Protects Cells: Ubiquinol protect cells of vital organ like heart from further damage and from constant attack by free radicals. Neuronal Health: Ubiquinol benefits the neurological system and promotes brain health. Studies carried out on patients who had Parkinson's disease have proved that it reduces the functional decline in these patients. Oral Health: Ubiquinol impacts the oral health and significantly enhances the salivary coenzyme Q10 levels. It affects all aspects of mouth, teeth, lips, tongue, and salivary glands. Renal Health: Studies show that Ubiquinol gives significant renal protection to patients who have chronic kidney disease. Your body constantly produces powerful antioxidants daily when you are young. But as you age, your body can not sustain this natural production level forever. Hence ubiquinol supplementation is important to promote overall good health. Ubiquinol can be used as a dietary supplement. Its ready-to-use formula is eight times more effective as it can be readily absorbed by your body. Thus it is an ideal diet supplementation for current CoQ10 users.
At present there are no known side effects of ubiquinol, but if you are on multi-drug therapy or are already taking other supplementations, then please consult your doctor prior taking this diet supplementation Ubiquinol.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2605) Lecithin And Its Brain Boosting Properties
Date:
March 02, 2012 07:10 AM
LecithinLecithin is a group of fatty substances, which occur in the tissues of plants and animals. It composed of fatty acids, choline, phosphoric acid, triglycerides, glycolipids, B vitamins, glycerol, and phospholipids. Liver produces this substance daily if you follow a complete nutritional diet. Lecithin is also inevitable for all cells in your body,protecting your cells from oxidation, and it is a major building block of cell membranes. It also supports the circulatory system of your body because it is a fat emulsifier too. Its Discovery The first isolation of lecithin was done by a French pharmacist and chemist, Theodore Gobley in 1846 and he named phosphatidylcholine Lechithine in 1850. He isolated it originally from egg yolk. Today, lecithin can very easily be extracted mechanically or chemically from soybean, grape seed, and sunflower. However, in plants, the most common source of lecithin is soybean. This substance is used for medicinal purposes and as a food supplement. Sometimes, it is used as an emulsifier in cooking for preventing sticking. Your body gets adequate amount of lecithin from your diet because it is naturally found in foods such as soybeans, egg yolk, peanuts, yeast, legumes, fish, wheat germ, grains, etc. It is also available in the market in the form of capsules, granules, and powder. This is also used as a supplement for promoting weight loss. Besides, you can also take lecithin in the form of pill or mixed in health shakes. Health benefits of lecithin It is believed that lecithin is beneficial for solving a number of health problems. So it is effective for:
* Cell communication, Brain Boosting Properties of Lecithin The major brain chemical for improving memory is acetycholine and the deficiency of this chemical is the major cause of declining memory. This chemical can be derived from nutrient choline. Fish is a rich source of acetylcholine. It can also be obtained from eggs, nuts, peanuts, soy beans, liver, etc. Eating more egg is beneficial for enhancing your memory. There are lots of studies has been conducted for finding the effectiveness of lecithin in improving the memory. As per the findings of experts, lecithin is highly effective for improving concentration, memory, and for preventing Alzheimer's disease and maniac depression (bipolar disorder). Lecithin helps to run your brain smoothly by improving insulation around the nerves. A major part of cell membranes consists of lecithin and it is essential for the proper functioning and growth of nerve. Organ meats and egg yolks are rich sources of lecithin but the usage of these products is very less due to the fear of cholesterol. Experts think that this is the major reason for the increase of concentration and memory problems. If you use lecithin properly, you can improve your concentration, memory, mind and nerves.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2599) What Are The Health Benefits Of L-Carnosine?
Date:
February 28, 2012 07:53 AM
L-CarnosineAmong the numerous natural compounds in the body, L-Carnosine is also one such beneficial compound that is naturally contained in the human body. Numerous health benefits are offered by this compound, and it plays an integral role in maintaining the wellness of an individual. However, as people begin growing old, are frequently stressed or have undergone some sort of a trauma, then the levels of this compound in the body are decreased. What is L-Carnosine? This compound is basically a dipeptide that comprises of alanine and histidine, which are two different types of amino acids. The brain, heart, kidneys, muscles, skin and the stomach are the organs where L-Carnosinecan be naturally found. Due to its potent antioxidant traits, this dipeptide is regarded as an effective anti-aging agent. What Are The Health Benefits Of L-Carnosine? As mentioned, Carnosine is an integral dipeptide in the body and quite an array of benefits are offered by it. Due to the intense antioxidant qualities of L-Carnosine, the free radical damaged caused within the body is minimized. Free radicals are not good for the cells present in the body since they damage and kill cells, and can also alter DNA too. Thus, Alzheimer's disease, heart disease, cancer and skin damage, are some of the health problems people can suffer from as a result of altered DNA, damaged and dead cells due to free radicals. In comparison to vitamin E, this compound can protect cell membranes from oxidation more effectively because it is water-soluble. Other Carnosine Benefits The compound also helps in healing wounds as well. The connective tissues in the body are effectively repaired thanks to the antioxidant qualities of Carnosine, and the skin is ideally healed. The compound also helps reducing the risk of wound infection too. Cataracts and other eye conditions can also be relieved with the help of the health benefits offered by this compound. Even though this compound is naturally contained in the eye, however, as people get older, its amount lessens. Thus, primary and mature senile cataracts can be effectively cured with eye drops containing L-Carnosine. Even the heart is kept healthy by this compound as well. The heart tissue muscle is strengthened by this compound and enzymes that enable the heart muscles to contract are also activated by it. How to Increase the Level of L-Carnosine in the Body? Those who want to increase the amount of this beneficial dipeptide in their body should eat a diet that essentially includes fish, meat and poultry. Dietary supplements can also supply the body with this compound. L-Carnosineis contained in certain multivitamin supplements, which contain various other amino acids, minerals, vitamins and other special nutrients. Thus, the overall positive effective of this compound in the body can be further enhanced by taking such supplements. As long as the supplement being used contains nothing but natural ingredients, supplementing this compound in the body can help an individual avail many health benefits. L-Carnosine is, therefore, an important dipeptide and those who are growing old should consider supplementing it through diet or supplements.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2595) Guggul: An effective remedy to lower cholesterol levels in the body
Date:
February 22, 2012 11:34 PM
GuggulGuggul is a popular herb in Indian Ayurvedic medicine that is used to treat several ailments. Due to its miraculous healing properties, it has been used for centuries in India to treat a range of health conditions. Recently many clinical studies have been carried out to find out the potential health benefits of herb guggul. Research has shown that guggul helps in lowering total body cholesterol, especially the bad ones-LDL and triglycerides. Before we move on to find the positive effects of guggul on heart and cholesterol levels, let us find out the more about this wonder herb. Guggul Herb: Botanically known as Commiphora mukul, guggul is a small shrub reaching up to a height of 4-6 ft. It is found in Central Asia, more common in India. It possess red colored flowers, thorns on branches and oval pulpy fruits. Guggul is prepared from the gum resin that is excreted by the bark of the plant. It contains phytosterols named guggusterones, aromatic acids, steroids, sterols, lignans, fatty acids, organic acids and diterpenes. According to Indian traditional system of medicine, Ayurveda, guggul contains hot potency which helps in treating diseases caused by vata dosha prominence. It treats coating and obstruction of channels that helps in treating and preventing atherosclerosis and other medical conditions caused due to high levels of lipids in the body. Raw guggul exudate is not safe and it is always used after purification in milk. How does the herb guggul help maintain good cholesterol levels? The exact mechanism by which guggul lowers cholesterol levels is still not understood, but many theories have been proposed. 1. Guggul works by blocking the synthesis of cholesterol in the liver. Hence liver does not release excess LDL or bad cholesterol in the blood, thereby reducing the risk of many heart diseases. 2. According to studies, guggul has an impact on the functioning of throid gland and production of bile acids in the body, both of which play an important role in the metabolism of cholesterol. 3. Studies have indicated the role of guggul in preventing oxidation of cholesterol. Oxidation of LDL cholesterol leads to formation of plaques in blood vessels and causes Atherogenesis. The antioxidant action of guggul inhibits cholesterol oxidation and reduces the risk of Atherosclerosis. The cholesterol lowering properties and antioxidant action make guggul a beneficial Anti-Atherogenesis agent. It can lower cholesterol levels by 14-17 percent and reduce triglycerides by 22-30 percent. Guggul and heart benefits: Guggul helps in promoting overall cardiovascular health. It reduces the adhesion of platelets and this reduces the rick of cardiovascular diseases. Studies have shown that Guggul when taken along with Inula racemosa helps in reducing chest pain and dyspnea associated with angina. It has potential cardi-protective benefits that keep your heart health. It helps in lowering blood sugar level and treating any inflammatory heart condition. Health supplements are prepared from the extract of this highly beneficial plant. Consult your health provider before you start taking guggul supplements. When taken in recommended doses, guggul helps you keep your heart healthy and fit so that you can live a healthy life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2589) Use Turmeric Herb Instead Of Cox-2 Inhibitor for Pain Relief
Date:
February 17, 2012 07:15 AM
What Is a Cox-2 Inhibitor? Cox-2 Inhibitor is a form of NASID. NASID stands for Non-steroidal anti-inflammatory drug which function to bring inflammation down. It is one of popular painkillers. It is very useful since medical science has gained information about serious problem about inflammation. Yet, it has been reported that it causes fast heart rate. It is a risky heart rhythm condition which is also named with atrial fibrillation. Medical experts said that it is a serious problem because it might lead to the risk of heart failure. Besides, it might also cause stroke and even death. As a form of NASID, Cox-2 Inhibitor will crucial to bring the inflammation down from a disease such as arthritis and an injury. In the United State, the common form of arthritis is Osteoarthritis. In short, this is the primary benefit of it. Besides that, it also functions as pain reducer. It is done by blocking proteins and enzymes made naturally by the body. However, it brings harm for our body on the other side. It seems to be side effects. Earlier research has noticed that it leads to the death. Inflammation solution As the solution, you can pick turmeric herb. It appears in a form of yellow colored spice. Similar to Cox-2 Inhibitor, it is very helpful for relieving the pain for arthritis. It is a perennial herb which originally grows in India. In the past, Indian people use it for cooking. Curcurmin becomes the most important part of turmeric. It is the most medicinal part contained in turmeric. We can easily find it in form of yellow color. Besides India, China has already use this herb in their daily live. For both Indian and Chinese, this herb has significant function as an anti-inflammatory. Besides, it also can be used as an antiseptic and several powerful ways. Besides for curing arthritis, turmeric herb is able to inhibit the spread and the growth of cancer cell. It has been proved by a university of Texas study. The result concluded from its research shows that turmeric herb prevents the breast cancer to be spread out to the lungs. It works together with our body by identifying the mutated cells and then it kills them. To make it more effective, it is suggested to combine turmeric herb with cruciferous vegetables. Other benefits of Turmeric Another benefit taken from turmeric herb is a protection toward our heart. For several countries especially the United State, heart disease has become the number one killer. In this case, this herb will play the role to prevent the oxidation of cholesterol. It is very important since the oxidized cholesterol might lead to the heart attack and stroke. It is because this oxidized cholesterol is able to damage blood vessels. Cox-2 Inhibitor has benefits yet they are not equal with the side effects created such as heart attack and also stroke. Having had similar function, turmeric herb is highly recommended to take for pain relief. For long time, it has been used for anti-inflammatory too. In short, turmeric herb is better choice than Cox-2 Inhibitor.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2581) Various Health Benefits of Acai Berry-The Wonder Fruit
Date:
February 12, 2012 07:32 PM
Acai berry is a highly nutritious fruit that grows in Amazon valley situated in the rain forests of the Northern Brazil. Being very small in size, it grows on palm trees that are known as Euterpe Oleracea. Acai berry is rich in fatty acids, amino acids, fibers, anti-oxidants, minerals and various vitamins. The fruit itself is very delicious tastes like chocolate candy. As acai berry is so rich in antioxidants, it provides sufficient nutrition for fighting off all the harmful effects of free radicals, decreases high cholesterol levels, lowers high blood pressure and helps in reliving the joint pain. Aside from being a great source of energy, it helps body in fighting off infections by strengthening the immune system. Today acai berry is regarded as a top super food. Acai berry also contains large amounts of trace minerals, and phytonutrients. Its ORAC score (a measure of antioxidant levels) is much higher than any other vegetable or fruits tested on gram for gram basis. Its high fiber and protein content helps in boosting the body's immune system. Various Health Benefits of Acai berry 1. Weight Loss-Acai berry helps in increasing the body metabolism rate within few days thereby helping you in shedding those extra pounds. 2. Regular intake of Acai berry fruit helps all those who suffer due to lack of sleep. Its amazing nutrients help in inducing sleep in the people. 3. Acai berry helps in removing harmful toxins from the body. 4. It minimizes the inflammation of stomach and liver to a great extent and assists in oxidation. 5. It helps all those who are suffering from depression and strengthens the cardiovascular system. It also regulates the nervous system in the body leading to better functioning by various body organs. 6. It provides relief to all those who are suffering from acute arthritis pain. 7. Speeds up recovery process in case of injuries. 8. Controls diabetes and stabilizes blood sugar level. 9. Sharpens eyesight and improves the functioning of digestive system. 10. Antiviral properties- Acai berry is rich in Anthocyanins (compounds found in red wine) which have good antiviral properties and boost your immune system which help you in fighting off diseases and illnesses. 11. Antiallergenic properties- Due to the presence of Antocyanins, the Acai berry has excellent antiallergenic properties. 12. Good fiber content- Fiber contents helps in cleansing your body by flushing out toxins. It also make you feel full with less food. Acai berries have 4 grams of fiber for every 100 grams of serving. 13. Lowers bad cholesterol-Acai berries are rich in Omega-9 and Omega-6 fatty acids that lowers LDL cholesterol which hardens arteries leading to heart disease. Best Colon Cleansing Agent Acai berry is a good colon-cleansing agent and also helps in detoxifying the body in a natural way. It acts swiftly on the midriff region, and enhances the weight loss in your tummy area. You can get Acai berry in various forms such as pills, snack bars, powder and fruit juices. Many world class companies offer their Acai berry products to world wide customers. You can even get freeze dried Acai berries as they have the highest concentration of nutrients in them.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2572) Benefits Of Zeaxanthin
Date:
February 07, 2012 08:14 AM
With aging, our eyes and the associated muscles weaken. They can degenerate and lose our ability to see properly. Eyes enable us with vision to see the world, and losing the eyesight will halt affect our daily activities and movements. People are frequently worried about losing their sight, and try to find supplements that can prevent the loss of vision. However, this debility can be prevented. Supplements should be ideally be all natural, healthy, and with no side effects. Zeaxanthin is an important nutrient for eye health. This is found in found in green leafy vegetables, and also in other foods like eggs. Zeaxanthin fulfills most of the requirements that most people look in a supplement. WHAT IS ZEAXANTHIN Zeaxanthin and lutein are carotenoids that filter out the harmful high-energy wavelengths of light, and also act as antioxidants in the eye. This helps to maintain and protect healthy eye cells. Out of the six hundred carotenoids found in nature, only these two, Zeaxanthin and Lutein are deposited in high quantities in the retina (macula) of the eye. Unfortunately, our body does not synthesize the zeaxanthin and lutein it requires. This is the reason why green vegetables, eggs and other sources of these carotenoids are essential to proper nutrition. Daily intake of zeaxanthin and lutein through diet, beverages, fortified foods or nutritional supplements and is very important for the protection and continuation of good eye health. Studies have indicated that zeaxanthin and lutein can help to lessen the chance of chronic eye illnesses, including cataracts and age-related macular degeneration (AMD). Zeaxanthin, is also a bioflavonoid, that besides its benefits to ocular health, has been linked to providing many health benefits, including its anti-inflammatory property. Because of zeaxanthin being a carotenoid category bioflavonoid, its main action is over the blood vessels; it works by supporting the blood vessels around the retina area with their proper function. ZEAXANTHIN BENEFITS Zeaxanthin is both an anti-inflammatory phytochemical and an antioxidant; hence this has been used as a preventative measure for macular degeneration and cataracts. Its antioxidant properties keep eyes from being damaged from the harmful ultraviolet rays of the sunlight. Overall, zeaxanthin keeps the eye healthier, and looking younger. ZEAXANTHIN AGAINST CATARACT: Our natural eye collects and focuses light on the retina, and to properly provide this function continuously, the lens must remain clear throughout life. A major cause of cataracts is oxidation of the lens, which clouds it. Antioxidant nutrients, like zeaxanthin and lutein neutralize the free radicals or the unstable molecules associated with this oxidative stress associated with retinal damage. Thus, these phytochemicals play a role in cataract prevention. Higher dietary intakes of vitamin E, zeaxanthin and lutein can considerably reduce the risk of cataract formation. ZEAXANTHIN AGAINST AGE-RELATED MACULAR DEGENERATION (AMD): Zeaxanthin and lutein reduces the risk of AMD. In fact, studies like AREDS2 (Age-Related Eye Disease Study) are being conducted with supplements containing ten mg lutein along with two mg zeaxanthin each day, how it affects or lowers the chance of developing this degeneration. FOOD SOURCES OF ZEAXANTHIN Zeaxanthin is naturally found in some green leafy vegetables like kale and spinach. Other sources of zeaxanthin include egg yolk, yellow squash and bell-peppers. This makes zeaxanthin available as a completely natural nutrient, with no side effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2559) Can Apple Cider Vinegar Help With Cholesterol And Triglycerides?
Date:
December 05, 2011 09:40 PM
Apple Cider Vinegar And CholesterolApple cider vinegar is a classification of vinegar which is derived from apple or cider. As you can observe, apple has an acidic taste which makes it possible to be processed into a type of vinegar. Apple cider vinegar is pale yellow to amber in color. This kind of vinegar may be pasteurized or unpasteurized. Non - processed or unpasteurized form of apple cider vinegar has a semi - solid or firm appearance because of its thickness and cobweb - like make - up. This form of apple cider vinegar is considered to be the “mother of vinegar”.Apple cider vinegar is yielded by mashing the fruit and squeezing out the juice it contains. Friendly microorganisms such as bacteria and yeasts are usually combined into the extracted juice to allow alcoholic fermentation. These microorganisms are the ones responsible for converting the sugar contained in the apple extracted juice into its alcohol form. Apple cider vinegar undergoes a second fermentation process. The alcohol produced from the first fermentation process is converted into its vinegar form by adding an ample amount of acetic acid – forming bacteria specifically known as Acetobacter. As a result, the juice extract will have a sour taste because of the acetic acid and malic acid it contains after several fermentations. In the food industry, apple cider vinegar is commonly used as an ingredient of salads, marinades, food preservatives and the like. Aside from its acetic acid content, apple cider vinegar also contains amino acids, vitamins and minerals. Clinical studies on whether apple cider vinegar can help control the amount of bad cholesterol and triglycerides in the blood have shown significant results. Yes, apple cider vinegar can have promising effects on the regulation of serum cholesterol and triglycerides. However, the studies also revealed that this fruit extract must not serve as a substitute for the medications prescribed by your doctor to regulate blood cholesterol and maintain or improve cardiovascular health. In animal studies, apple cider vinegar has shown positive effects on lowering triglycerides by almost 50 %. However, effects on Low Density Lipoprotein or the so – called “bad cholesterol” are not that efficient. Needless to say, the American Heart Association stated that a good lifestyle and balanced diet can effectively reduce the amount of bad cholesterol and triglycerides in the blood. Apple cider vinegar will also greatly help in lowering these substances in the blood. Other studies have also revealed that the acetic acid content in apple cider vinegar stimulates the expression of the genetic material which activates fatty acid oxidation enzymes. As a result of this biological process, there will be a significant lowering or control of body fat accumulation by the liver. This is the reason why apple cider vinegar can also be employed as a weight loss agent. Apple cider vinegar is all – natural. Therefore, safety is relatively established. However, health experts still suggest that before you start using this product, you have to consult your doctor and discuss your current and past health condition as well as the other medications you are taking. This will reduce the incidence of adverse health reactions and drug to drug interactions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2540) How Much Turmeric Should Be Taken For Alzheimer's?
Date:
October 05, 2011 02:08 PM
Turmeric is an herb which is a perennial plant included in the family of gingers. This plant is considered to be rhizomatous and has been found to be abundant in tropical countries such as South Asia. For its cultivation, this plant must grow in a climate with a temperature of 20 to 30 degrees Celsius and ample amount of yearly rain. In these kind of climates, this herb can grow healthy and abundantly. In some countries, an annual collection of rhizomes is done and then reproduced and grown the next season. Turmeric is commonly used as a culinary spice or ingredient. It is dried in extreme temperatures of ovens and ground into a yellow to orange powder. This spice is common in many Asian dishes. Aside from its culinary use, it can also be helpful in maintaining the health of the human body. The known active ingredient of turmeric is Curcumin. This chemical substance has a unique slightly metallic taste and peppery in flavor. It also has a mustard–like aroma. Hence, it is considered to be an important condiment in many Middle Eastern recipes. In addition to Curcumin, turmeric consists of about 5 % of essential oils. With its many health benefits, one of the most interesting is its effect on the brain in helping prevent the onset of Alzheimer’s disease. Clinical studies and surveys reveal that people who consume large quantities of curry have a lesser risk and incidence of having Alzheimer’s disease. Therefore, intensive studies are being conducted to test and prove its safety and effectiveness as a chemical substance which can greatly help in the prevention of the increasing number of Alzheimer’s disease cases. Other factors are also considered such as the individual’s diet, familial history, social and economic status as well as lifestyle. Alzheimer’s disease has been closely related to the increasing damage of brain cells due to oxidation. This brain damage will significantly cause an effect to the person’s memory thus Alzheimer’s disease occur. Curcumin in the turmeric has the potent capacity to prevent this cellular damage thus slowing the development of such disease. Studies have also shown that Curcumin can significantly impede certain mechanisms that are involved in the progress of Alzheimer’s disease. Aside from its benefit in decreasing the risk of Alzheimer’s disease, turmeric also has a potential anti – inflammatory property and can effectively regulate blood cholesterol levels. The recommended dosage of turmeric has not yet been officially established. Therefore, if you are planning to supplement with turmeric, it would be best that you should consult your doctor. The dosage of this supplement varies from person to person in terms of age, weight, other health conditions and status of his/her Alzheimer’s disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2482) What Is the Life Span Of Human Cells And How Do Antioxidants Help?
Date:
August 25, 2011 10:38 AM
The human body is composed of many different cells. These cells have varying functions as well as life span. The human cells, in general, are very complex. Some cells may last only within a day while others may be for life. Like for example, one blood component known as neutrophil lasts only within 24 hours. On the other hand, another blood component which is red blood cell has a life span of 120 days. One human cell which lasts for a lifetime is the stem cell. Stem cells are undifferentiated cells which are the source of blood cells. They supply the body throughout life both with red and white blood cells. Here is a brief outline of some cells of the human body with their corresponding life spans. 1. Granulocytes such as eosinophils, basophils and neutrophils – half day to 3 days 2. Stomach and colon lining cells – 2 to 4 days 3. Sperm cells – 2 to 3 days 4. Epithelial cells of the small intestines – 5 to 7 days 5. Platelets – 10 days 6. Skin epidermal cells – 14 to 28 days 7. Lymphocytes, macrophages and endothelial cells – 2 months to a year, but may vary 8. Pancreatic cells – a year or more 9. Bone cells – 25 to 30 years As shown above, these human cells have an expected time of death. However, if the body is exposed to harmful toxins, their life span significantly decreases. As we know for a fact, the body undergoes many biological reactions almost every second. The reaction is called oxidation process which is essential to the body. However, such reaction has harmful by – products in the form of free radicals. Free radicals can cause the body significant damage. Free radicals can cause destruction and death of the healthy cells of the body and also affect the body’s cellular division. This kind of chemicals can potentially tamper DNA replication during cell division. Once cellular division is tampered, abnormal growths would likely happen. Aside from the naturally occurring free radicals, external stressors can also cause damage to the cells of the body. Some of these include pollutants, harmful chemicals and irritants. These harmful chemicals can potentially lead to the development of certain disease conditions such as heart diseases, stroke and cancer. Fortunately, there are many antioxidants which can greatly help in the prevention of free radical damage by protecting the cells of the body. Antioxidants are molecules which can effectively prevent the oxidation of other molecules. There are many natural antioxidants found among plants and animals. Some common antioxidants are glutathione, vitamin C and vitamin E. Other nutrients which have antioxidative property include beta – carotene, lutein, lycopene, vitamin A and selenium. Fruits and vegetables are great sources of antioxidants. Nuts, grains, meat, poultry products and fish are also good sources of such cell – protecting chemicals. In addition, dietary supplements of antioxidants are also widely available in the market. However, health experts highly suggest that before supplementation of antioxidants, medical evaluation must be done first to be completely safe.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2407) How Does Lycopene Help Improve Prostate Health?
Date:
August 18, 2011 10:16 AM
Lycopene is a bright red carotenoid pigment and phytochemical found in tomatoes and other red fruits and veggies, like red carrots, watermelons and papayas however not strawberries. Although most chemical carotenes has vitamin A activity, lycopene does not. Lycopene is an essential intermediate in the biosynthesis of many carotenoids and in algae, plants, and other photosynthetic organisms. An Anti-Oxidant? A term that describes a large range of more about 600 pigments which give plants their red, orange or yellow colouring is carotenoid. Some of the most commonly known in a regular Western region diets are alpha-carotene, beta-carotene, lutein, zeaxanthin, and lycopene. Attention has been paid most to alpha-carotene and beta-carotene since these are the ones that can be synthesized by our body to form vitamin A, one of the body’s very powerful antioxidants. Lycopene, in particular, is has even been credited with some of the many anti-oxidant functions previously credited to beta-carotene. Prostate Health Prostate cancer is most common among men over the age of 50. The cause of this type of cancer, like almost all other cancers, is unknown, but some studies indicate alteration in testosterone metabolism possibly plays a role in its development. Prostate cancer generally grows slowly and can be undetected until late in the stage of the decease since it does not show any symptoms in the early stages. Symptoms can include painful urination, a feeling of incomplete emptying of the bladder, or blood showing with the urine. According to some studies prostate cancer patients that supplement with lycopene in addition to surgical procedures to remove the testicles may experience, less bone pain, and live longer than those who does not supplement. It has also shown that groups of patient that were tested with lycopene supplementation has a higher survival rate after a time frame of two years and no adverse side effects were observed in these men as well. This is achieved through lycopenes proven role in keeping the pathways open between cells which is vital in allowing the immune system to hold off cancer cells in its early stages. Although more research is still required to iron out what exact amount of lycopene will be most effective, the current results are already encouraging. However eating a moderately sized tomato a day can approximately provide 4 mg of lycopene and other tomato products, like an 8-ounce tomato juice or tomato paste provides up to 15 mg of lycopene just to give all the men out there an estimate. These are small portions of the diet that could easily be added without any major adverse effect to weight or health and seems too small to ignore given the possible benefits and minimal negative effects if any. Additional Lycopene Benefits It also has been found that lycopene can possibly as important as beta-carotene in protecting against the process of oxidation of Low Density Lipids (LDLs), also known as the “bad cholesterol”, which is now held to be the main cause of atherosclerosis, or hardening of the arteries which leads to cardio-vascular diseases like stroke or heart attack. Grab Some Lycopene today and experience the benefits for yourself!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2398) Fight Pain Improve Blood Sugar And Heart Health with OPC Pine Bark Extract
Date:
June 07, 2011 11:36 AM
How Does OPC Pine Bark Boost Your Health?OPC pine bark has become increasingly popular in the supplement industry due to obvious reasons. It is one of the best antioxidant formulas available today. There has been so much research involved in its development, and the studies that followed have published largely positive results. In the past few years it has received a lot of good press, which has significantly contributed to its commercial success. OPC stands for oligomeric proanthocyanidin, a class of flavonoids. OPC has been in use as a nutritional supplement since the 1980s. To this day, it remains an important source of polyphenolic antioxidants. Moreover, it has been linked to a diverse variety of health benefits, and laboratory studies concerning its effects on human health are well publicized. Pine bark extracts are one of its best known sources. Promotes Heart Health OPC pine bark has long been associated with heart health. For one, it has shown to help lower lipid levels in the blood, including cholesterol, triglycerides, and lipoproteins. It interferes with the productions of bad cholesterol into the blood and protects the blood vessels from lipid peroxidation. In addition, it facilitates normal flow of blood and combats chronic venous insufficiency. It contributes to the upkeep of blood vessel walls and keeps the veins and arteries in prime working condition. By so doing, it promotes proper circulation to the deepest reaches of the body and back to the heart. Improves Kidney Function OPC pine bark is particularly good for the kidney as it appears to improve renal function, especially in the context of metabolic syndrome. Central obesity, insulin resistance, diabetes mellitus, and high blood pressure are all symptoms of metabolic syndrome, which takes its toll on the kidneys. Kidney problems have been observed in people with elevated levels of albumin in the urine. When filters of the kidney are damaged, proteins from the blood such as albumin leak into the urine. OPC pine bark restores health to the capillaries in the kidneys that filters waste materials from the blood. Counteracts Pain Chemicals Sufferers of joint pain are likely to benefit from OPC pine bark. Joint pain is often tied to osteoarthritis, the most common form arthritis. It is often accompanied by stiffness and reduced mobility. OPC pine bark has been used as a therapeutic treatment for osteoarthritis and other causes of joint pain. There is good evidence that OPC pine bark is effective in counteracting pain chemicals and relieving inflammatory pain. In several randomized, double blind, placebo controlled studies, regular intake of OPC improved joint pain and stiffness, reduced reliance on analgesics, enhanced physical function. Prevents Oxidative Stress OPC pine bark is free radical scavenger, first and foremost. It is arguably the most researched plant polyphenol largely owing to its potent antioxidant capacity. As an antioxidant, it prevents radical damage from progressing to oxidative stress and promotes cellular longevity. OPC Pine bark may also help manage blood sugar. What is stopping you from taking OPC pine back daily?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2325) Control Cholesterol, Loose Weight, Regulate Blood Sugar, And More With Inositol
Date:
June 02, 2011 12:10 PM
What Does the B Vitamin Inositol Do for the Body? Inositol is an organic compound that functions within the human body in the same way as nutrients. Its vitamin-like activities are believed to be similar to other B vitamins. It plays an important role in the upkeep of cells, breakdown of fats, effects of insulin, activities of serotonin, and regulation of cholesterol, among others. It is usually obtained from plant-based food products that contain lecithin. Myo-inositol is the form most widespread in nature. It is also the form most active within the body as it has been associated with many physiological functions. It is no longer classified as an essential nutrient in that our body is capable of synthesizing it in adequate amounts. That being said, its vitamin-like activities and desirable health benefits have contributed to its popularity as a supplement. Reduces Cholesterol Levels One of the biological roles of inositol is to help regulate cholesterol levels in the systemic circulation. This nutrient even reduces overall lipid levels. It limits the conversion of very-low-density lipoproteins to low-density lipoproteins, or bad cholesterol. In addition, it promotes the releases of high-density lipoproteins, or good cholesterol, which contains lower amounts of lipids. By so doing, it lowers free fatty acids and other lipids in the blood and protects the blood vessels from lipid peroxidation. Modulates Serotonin Activities Inositol is directly involved in the activities of what we refer to as the happiness hormone, which is the neurotransmitter serotonin. In fact, this nutrient has very visible impact on the effects of serotonin on mood, appetite, sleep, and muscle contraction. Healthy levels of inositol increases the overall tolerance of the human body to risk factors and creates a general feeling of physical well being. Induces Weight Loss Fat metabolism relies on the presence of inositol, the reason why this B-vitamin-like compound is commercially touted to aid weight loss. Inositol participates in the chemical reactions that lead to the breakdown of fats. Consumptions of foods rich in inositol have shown to increase effective utilization of fat reserves found in adipose tissues, such as the unwanted subcutaneous body fat. Proponents of supplementation believe that inositol induces breakdown of fats even while sleeping. Regulates Blood Sugar The hormone insulin is responsible for regulating blood sugar levels throughout the day. It sends signals to individual cells that promote the uptake of glucose from the blood. Glucose is of course what fuels cellular activities, and thus contributes to the metabolism of compounds utilized by cells. Inositol enables insulin to initiate signal transduction and communicate effectively with cells in the process. Improves Mental Disorders Inositol has long been linked to the improvement of mental disorders. It has been observed that individuals diagnosed with clinical depression have low levels of inositol in their cerebrospinal fluid. Supplementation appears to rebalance brain chemicals, enhance mood, and improve mental illnesses, such as bipolar disorder, obsessive-compulsive disorder, anxiety disorder, panic attacks, major depression, and Alzheimer’s disease.
Improve Your Health with Inositol.Grab some inositol today and improve your cardiovascular health naturally!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2318) Protect Your Heart with Wheat Germ Oil
Date:
May 26, 2011 02:04 PM
Wheat Germ And Heart Health.Wheat germ oil can protect your heart and entire cardiovascular system from damage, particularly from the effects of cholesterol and conditions such as peripheral artery disease. Atherosclerosis is a condition caused by the free radical oxidation of LDL cholesterol that is then precipitated and deposited onto your interior artery walls. This eventually blocks your arteries, causing strokes and heart failure depending on where the affected arteries are situated. Peripheral artery disease (PAD) is a condition where the arteries in your legs are blocked or partially blocked so that blood cannot reach your feet. This causes infections and pain. By taking wheat germ oil, you can zap the free radicals before they can do damage to your cholesterol and hence to your arteries, and also prevent PAD the same way. The policosanol, another component of the oil, helps with this by increasing the proportion of HDL (good cholesterol) to LDL - bad cholesterol. There is then less LDL to undergo free radical oxidation, making the work of the antioxidants protecting it much easier.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2310) Why Are Fresh Sprouts Like Alfalfa, Barley, and Wheat So Good for Your Health?
Date:
May 24, 2011 11:22 AM
Sprouts For A Healthier Body!Fresh sprouts are among the healthiest of all foods. They are rich in enzymes that are not found in the human body. These enzymes help facilitate better absorption of vitamins and minerals. Alfalfa, barley, and wheat are examples of plants that are capable of sprouting when soaked in water. They are best consumed fresh when they still contain all of their nutrients. They make excellent ingredients to salads and sandwiches that can complement any meal. They can be processed in juicing machines, too. You might have heard of the nutritional value of grasses and legumes. Wheatgrass is becoming increasingly popular nowadays as they have been receiving a lot of good press lately. Wheatgrass and barley grass has in fact earned the moniker superfoods. Alfalfa, on the other hand, is a legume recently rediscovered for its phytochemical content. It has been a forage crop for centuries, but human consumptions have steadily increased in the past few years. Apart from the fact that wheat, barley, alfalfa can be consumed as fresh sprouts, they also bring similar benefits to human health. Restore Normal pH Levels Proponents of the alkaline diet believe that the body is in a constant cycle of alkalinity and acidity, which is partially dependent on the foods that we eat. The body raises alkalinity with every acidic by-products of digestion to maintain pH balance. That being said, a significant fraction of the human diet is acid-forming, tipping the balance in the process. Fresh sprouts are often linked to the alkaline diet, which aims to restore pH balance of the body. Have High Nutrient Content Alfalfa, barley grass, and wheatgrass are very good sources of vitamins and minerals. They are particularly rich in dietary minerals that help the body function at its best. Plus, they contain amino acids, essential fatty acids, dietary fiber, and carbohydrates in amounts adequate to complement any other foods that make up a healthy diet. One of the very noticeable improvements after months of consuming fresh sprouts is the increase in red blood cell count. Cleanse the Body of Toxins Aside from the fact that fresh sprouts are effective free radical scavengers, they also improve the natural antioxidant defense of the human body. Wheat, barley, and alfalfa are reliable sources of potassium, magnesium, manganese, and selenium, all of which are involved in chemical reactions that lead to effective removal of toxic by-products of metabolism. Fresh sprouts are capable of neutralizing reactive oxygen species such as free radicals. Furthermore, they facilitate the excretion of toxins. Promote Heart Health Fresh sprouts are particularly good for the cardiovascular system. They maintain the health of red blood cells. They limit the releases of low-density lipoproteins into the blood, thus lowering bad cholesterol and free fatty acids. They help control high blood pressure and promote normal blood flow. They maintain healthy levels of blood sugar by improving glucose metabolism. And, of course, their antioxidant profile enables them to protect the heart and arterial walls from lipid peroxidation. Have you had your sprouts today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2304) Vitamin B2 Is Good for Nutrient Metabolism, Cellular Energy, And More
Date:
May 10, 2011 11:11 AM
Vitamin B2 is an essential nutrient. As its name suggests, it belongs to the B complex group of vitamins. The monosaccharide ribose is part of its chemical composition together with the ring moiety called flavin that gives its yellow coloration. Hence, it is also known by the name riboflavin. Inside the human body, it plays a central role in the synthesis of flavoproteins, which are involved in many chemical reactions, especially in the metabolism of other micronutrients and bioactive molecules. Deficiency in riboflavin is quite common as it is routinely excreted through the urine. Common symptoms include sore throat, seborrheic dermatitis, lower blood count, all of which have been tied to higher incidence of esophageal cancer. Chronic ariboflavinosis, the medical condition caused by vitamin B2 deficiency, has been reported to contribute to carcinogenesis. The good news is that it can be easily reversed with regular intake of foods rich in riboflavin or supplementation. Aids Nutrient Metabolism It is not a coincidence that vitamin B2 deficiency is often accompanied by deficiencies in other vitamins and minerals. In some cases, deficiencies may be attributed to impaired liver function or intestinal absorption. That being said, low levels of riboflavin do impact the metabolism of other vitamins, such as vitamin A, vitamin B3, vitamin B6, and vitamin B9, among other water-soluble micronutrients. Metabolites of riboflavin are required in the conversion of these vitamins to their active forms, for example, from vitamin A to retinoic acid, vitamin B6 to pyridoxic acid, vitamin B9 to folic acid. Furthermore, the metabolism of bioactive compounds, including fats, proteins, and carbohydrates, also necessitates the presence of this vitamin, the reason why it greatly impacts growth and development in children. Increases Cellular Energy In addition to its physiological potential in intermediary metabolism, vitamin B2 is also present in the generation of adenosine triphosphate, the primary transport of energy that powers intracellular activities. Adenosine triphosphate is synthesized in three different metabolic pathways, and one process called oxidative phosphorylation necessitates the involvement of flavin adenine dinucleotide, one of the active forms of riboflavin. Vitamin B2 is an important cofactor in all chemical reactions that result in an increase or decrease of oxidation state. These reactions are collectively called oxidation-reduction, or simply redox. Metabolites of riboflavin are reliable oxidizing agents capable of carrying high-energy electrons needed for oxidative phosphorylation. They also participate in beta oxidation, another metabolic pathway that yields cellular energy. Scavenges Free Radicals A nucleic acid derivative of riboflavin is an important constituent of a special class of organic compounds called flavoproteins. These proteins are found in almost all cells of the human body, and one of their functions is to protect the cells from oxidative stress brought on by free radicals. Vitamin B2 is present in the production of cellular energy and the removal of harmful by-products of energy metabolism. Insufficient intake of vitamin B2 is deleterious to human health, inasmuch as its biological roles are quite pervasive at the molecular level. Do you get enough Vitamin B-2?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2292) What is the Amino Acid Taurine and How Does It Boost My Health
Date:
April 26, 2011 02:26 PM
Taurine is a nutrient that improves cellular processes by regulating mineral salts in the human body. Many people consider it as an amino acid as it is derived from seafood and meats. It is not an amino acid in the strictest sense, but a naturally occurring sulfonic acid. It is pivotal to removing the water in the bile. Bile acids are produced in the liver in the presence of taurine and stored in the gallbladder. Enhances Physical Capacity Many energy drinks describe taurine as an active ingredient. Several groups of researchers believe it affects athletic performance, drawing on its biological roles. For one, taurine is necessary for the upkeep of skeletal muscles, and in athletes appears to lengthen duration of physical exertion. Also, it is implicated in chemical reactions in the nervous system, boosting mental clarity. Counteracts Hypertension There is evidence that taurine has an effect on blood flow. In the circulatory system, taurine is important to regulating the level of water and minerals. It is widely accepted that it modulates the movement of elements and their metabolites in the blood, such as calcium, potassium, and sodium. In fact, taurine has been observed to significantly decrease high blood pressure in hypertensive patients. Promotes Liver Health Taurine is especially good for the health. Numerous studies have noted the effects of high levels of taurine on liver cells. It has been proven effective in removing any adiposity in the organ. Clinical trials have published results that emphasize its benefits to people with liver diseases, such as hepatitis and cirrhosis. It has also been observed that high intake of taurine counters hangover. Lowers Serum Lipid Levels In the liver, taurine plays an important role in inhibiting the releases of apolipoproteins, a class of proteins that bind with lipids to form lipoproteins. Apolipoprotein B makes up very-low-density lipoproteins and low-density lipoproteins, or what we refer to as bad cholesterol. This is the reason why taurine has been suggested to help people afflicted with cardiovascular diseases. Normalizes Blood Sugar It has been postulated that taurine protects the beta cells of the pancreas, the organ responsible for the manufacture of the insulin. Patients diagnosed with type 1 diabetes mellitus have been reported to experience an improvement in insulin levels. Taurine is also helpful for type 2 diabetes as it also appears to enhance glucose sensitivity of cells, thereby decreasing glucose levels in the blood. Scavenges Free Radicals Taurine is an antioxidant known for its wide-ranging benefits. It is almost always associated with oxidative stress brought on by physical exertion as it protects the skeletal muscles from the damaging effects of free radicals. More importantly, it protects the liver, the pancreas, and the circulatory system from the toxic by-products of metabolism, notably during oxidation of chemical compounds. Given the health benefits of Taurine, everybody should be taking some daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2282) Is There Any Benefit to Taking Grape Seed Extract?
Date:
April 15, 2011 02:12 PM
Grape Seed Extract And Your Health!Grape seed extract has been linked to many health benefits. It is entirely derived from grape products, but contains higher concentrations of organic compounds naturally occurring in grape seeds. It has long been known that grapes are excellent sources of bioactive compounds while grape seeds have more phytochemicals. In addition to their long list of all-natural antioxidants, such as tocopherols, flavonoids, and oligomeric proanthocyanidins, grape seed extracts contain the essential fatty acid linoleic acid, the reason why they are exceptionally good for the skin.Accelerates Wound Healing The circulatory system is the best venue for nutrient distribution throughout the body. The tissues that have direct access to the blood vessels are more likely to receive nourishment and heal faster in the process. Grape seed extracts induce the productions of proteins called vascular endothelial growth factor, which stimulates the growth of healthy blood vessels, thereby accelerating wound healing in any part of the body. Improves Bone Density Grape seed extracts have been noted to increase bone mass and strength. The bones are the primary storage of inorganic minerals in the human body, like elemental calcium. As such, they undergo a lifetime cycle of resorption and reabsorption to respond to the mineral needs of other body parts. Any imbalance in the process may result in bone porosity. It is postulated that the phytochemical content of grape seed extracts inhibits bone resorption. Promotes Integumentary Health Oligomeric proanthocyanidins, or OPCs, are of special note for their unique antioxidant activities. They are capable of scavenging free radicals and preventing cellular damage. At the same time, they protect the skin, the scalp, and the rest of the integumentary system from the harmful oxidative effects of ultraviolet rays. Grape seed extracts are particularly rich in OPCs, which have been tied to impede skin tumor growth. Shows Cardioprotective Effects Grape seed extracts contain an abundance of organic compounds that promote cardiovascular health. First, it has shown to be effective in lowering low-density lipoproteins, also known as bad cholesterol. Second, its antioxidant properties prevent the oxidation of bad cholesterol, which results in the formation of arterial plaques if subjected to oxidative stress. Third, grape seed extracts reduce complications of preexisting cardiovascular disorders. Eases Digestive Problems Grapes have long been reputed as a digestive in many cultures. Grape seed extracts, having flavonoids with bioactive properties, serve as a cleanser of the alimentary canal. They aid digestion and modulate the effects of enzymes on food. The same organic compounds limit the growth of microorganisms that populate the colon, which is the cause of many disorders of the gastrointestinal tract. Prevents Tooth Decay Grape seed extracts contain phenolics that interfere with the metabolism of sugars in the oral cavity. The bacteria that take up residence in the mouth rely on the availability of saccharine compounds, and they thrive well in the presence of simple sugars, such as sucrose, fructose, and glucose. Dental carries result from an abundance of these sugars and a growing bacterial population. Grape seed extracts impact both. As you can see, grape seed extract has many health benefits. All who want to keep their body’s working in tip top shape should be taking grape seed extract daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2275) What Does The Ayurvedic Herb Amla Do For The Body?
Date:
February 22, 2011 02:25 PM
Alma And Your HealthAmla is an herb famed for its high content of antioxidants, notably vitamin C. The berries, which are utilized as a source of food and in the production of dietary supplement, come from the plant species Phyllanthus emblica, or more commonly identified as Emblica officinalis, but other parts of the plants such as the leaves and bark have also been used in preparations in treatment of various diseases. Also known as Indian gooseberry in the vernacular, amla is an important herbal remedy in Ayurvedic medicine, a system of medical practices native to India. It is also extensively used in Unani practices, which cover the countries of the Middle East, largely owing to the influence of earlier Hippocratic medicine on the region. Scavenges Free Radicals Amla is touted to be among the fruits that contain exceptionally high concentrations of vitamin C. The berries yield up to 445mg per 100g, which is at least 20 times higher than the ascorbate content of oranges. In addition, the plant produces a unique free cascading antioxidant now called emblicanin, purported to have very strong antioxidant properties, seeking out free radicals and effectively scavenging large numbers by converting into another form of antioxidant after neutralizing the first. As you might already know, free radicals significantly contribute to the process of aging by producing effects related to oxidation. While the body manufactures endogenous agents that come to its defense, it has long been discovered that free radicals are able to multiply at an exponential rate and cause irreversible damage at the cellular level. This is the reason why supplementation of vitamin C as well as other antioxidants is advocated by the scientific community. Lowers Bad Cholesterol One of the studies concerning amla that have promising preliminary results is its use as a therapeutic remedy for elevated levels of blood cholesterol. There have been reports that the high density of tannins in amla is responsible for its effects on the production of low-density lipoproteins in the liver. These lipoproteins, notoriously labeled as bad cholesterol, is the main transports of cholesterol and triglycerides in the bloodstream and in the process gets attracted to the arterial walls, resulting in buildup of plaques associated to atherosclerosis and related heart diseases. Inhibits Bone Resorption Amla has also shown to have an effect on osteoclasts, which is involved in the degeneration of bone and cartilage tissues related to osteoporosis and many cases of arthritis. Intake of amla has been observed to induce death in osteoclasts and alter the gene expression in osteoclasts, thereby reducing bone resorption. That being said, it prevents further damages to bone and joints in patients of arthritis and osteoporosis. There have been many scientific researches concerning the age-old applications of amla in many common ailments, such as fever, cough and colds, and constipation, age-related diseases such as rheumatoid arthritis and diabetes, and even enhancing the memory. Most of these studies are limited to India and has largely drawn on anecdotal evidence of the local communities.
If you want to give your body a health boost, try the Ayurvedic herb Alma today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2242) Taurine - Essential or Non-Essential Amino Acid - You Decide?
Date:
February 17, 2011 10:56 AM
Amino Acid Taurine Is Essential For More Than You ThinkTaurine is an organic compound with acidic properties, which is synthesized in the pancreas in adults, but an essential amino acid in infants. Many neutraceutical products for infants are fortified with taurine, inasmuch as some newborns do not have the enzymes required to synthesize taurine. Taurine deficiency in adults results from deficiencies in other organic compounds, notably methionine and cysteine, which are its immediate precursors within the body. Helps in Brain Development It has long been postulated that taurine plays an important role in the human brain, especially in infants, protecting the nerve cells from possible neonatal damages. Taurine continues to affect the nervous system as we age, acting on gamma-aminobutyric acid, or GABA, and consequently enhances inhibitory synaptic transmissions. In addition, taurine is alleged to stimulate continuous activation of synapses characteristic of long-term potentiation, which memory and learning ability stem from. Stabilizes Glucose Levels Taurine is a powerful inhibitor of glycation, a process by which sugar molecules attach themselves to other biomolecules without the aid of enzymes, and thus subsequently impair the functions of these biomolecules. This process may take place inside or outside the body, but the substances that result from this process, which are referred to as advanced glycation end-products or AGEs, contribute to the formation of a number of major disorders in later life such as cardiovascular diseases, Alzheimer’s disease, age-related deafness and blindness, and cancer. Taurine keeps the cells from taking up AGEs from the blood, which is slowly excreted in the urine. Regulates Adipose Tissues It has also been observed that dietary taurine influences the metabolic pathways that give rise to the formation of adipose tissues, the fat reserves of the human body. These fat depot appear anywhere in the body, but are commonly tied to the subcutaneous fats, those that we see on the belly, chest, arms, and thighs. Moreover, body fat percentage has been an indicator of obesity, which is central to the use of taurine in regulating adipose tissues. Influences Lipid Absorption Taurine is a major component of bile, the fluid produced by the liver, stored in the gallbladder, and secreted in the small intestines to aid in the digestion of triglycerides, cholesterol, and other lipids. Also, several studies point to the effect of taurine on the binding of proteins to lipids to form lipoproteins, compounds that have been notoriously labeled as bad cholesterol. Not surprisingly, taurine has been suggested to maintain healthy levels of blood cholesterol and prevent cardiovascular diseases. Fights Oxidative Stress Sodas have become a part of our daily diet today, but little did we know that they are risk factors for oxidative stress, the continued peroxidation of cellular structures. Fructose in sodas and other sweetened beverages is the most dangerous of all sugars, inasmuch as it releases by-products called AGEs, which are highly reactive to oxidation. AGEs do not get excreted right away and are instead absorbed by cells, leading to irreversible damages to neuronal and vascular tissues in later life. Intake of taurine removes this problem. Have you had your Taurine Today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2239) Lycopene is More than Just a Tomato Extract!
Date:
February 08, 2011 04:38 PM
Lycopene is a naturally occurring antioxidant, and a very powerful one at that. Like beta-carotene, it is a carotenoid, a phytochemical that gives certain plants their orange or bright red pigmentation. While lycopene belongs to a group of carotenoids called carotene, known precursors of vitamin A, it does not get converted into vitamin A inside the human body, which is not a bad thing, inasmuch as lycopene in itself exhibits antioxidant properties that surpass the effects of vitamins. Tomatoes are very rich in lycopene, and indeed consumptions of tomatoes have been reported to show the antioxidant properties of lycopene. Papayas, pink guavas, and watermelons are also good sources of this compound, but the plant source identified to have the highest concentrations of lycopene is Gac, in English also known as Sweet Gourd, a bright red fruit native to Southeast Asia and largely unknown to the rest of the world. With that, a significant fraction of the total lycopene consumption worldwide is derived from tomatoes. Reactive Oxygen Species (ROS) Chemical reactions in the human body that respond to the presence of oxygen are part of a process called oxidation, which takes place everywhere else in nature. These reactions entail a change in the oxidation number of atoms or molecules involved in the movement of electrons between molecules inside the body, giving rise to toxic by-products collectively known as reactive oxygen species. When cells produce the energy that they use to power their physiological functions, they also produce reactive oxygen species, or ROS, which is now believed to be a key factor in the progression of physical infirmities associated with the aging process of human beings and other mammals. That being said, ROS are actually in the employ of the immune system, and particularly effective against pathogens, which may be invasive extracellular matter or harmful microorganisms. Every single cell make use of enzymes that change the chemical makeup of unnecessary ROS, which must always be kept in check as they damage cells even at low amounts. These enzymes outmaneuver the damaging activities of ROS, thereby protecting the cells. In spite of that, the human body is known to produce more ROS as we age or during long-standing exposure to stress.
Lycopene versus ROSOne type of ROS is singlet oxygen, a form of oxygen that is highly reactive to free radicals. In fact, singlet oxygen is a known catalyst of free radicals especially when it gets excited at the molecular level. Lycopene is the best known carotenoid to counter the damaging effects of singlet oxygen in the human body, and reported to have antioxidant properties far superior to vitamin E and glutathione. The good thing about lycopene is that its bioavailability compounds when exposed to heat, so cooking tomatoes actually brings out the goodness of this chemical compound. Lycopene acts against the proliferation of cancer cells in a number of mechanisms, and, to date, there have been innumerable reports in support of the role of lycopene against most known types of cancer.
Have you had your Lycopene today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2232) The Krebs Cycle - Our Lifes Blood!
Date:
January 13, 2011 05:00 PM
The Krebs Cycle, also known as the Citric Acid Cycle, is an important series of biochemical reactions that are intrinsic to cellular respiration and the generation of energy from oxygen and glucose in aerobic organisms. Although humans can generate energy anaerobically, they cannot do so for long periods and oxygen is essential for life because it fuels the Krebs Cycle. Without this cycle, there would be no available energy to maintain our vital processes.
What is The Krebs CycleWe shall first discuss exactly what the Krebs Cycle is and then its importance in the body. The process takes place within the mitochondria of the body cells. A. The cycle begins with the ten-step pathway of glycolysis, during which glucose is converted to two molecules of pyruvate: no oxygen is required for this step. Basically: Glucose + 2NAD+ + 2P + 2ADP = 2Pyruvate + 2NADH + 2H+ + 2ATP The pyruvate can then undergo aerobic or anaerobic respiration to generate energy. The Krebs Cycle is the aerobic route, and significantly more efficient that the alternative fermentation. B. The two pyruvate molecules are then oxidized to two of Acetyl CoA with the release of carbon dioxide. The two acetyl groups of the Acetyl CoA are donated to Oxaloacetate in the presence of water to form Citrate. C. Citrate then undergoes a number of chemical reactions to arrive back at Oxaloacetate again and the cycle starts all over again by reacting with more Acetyl CoA from Pyruvate and oxygen to form Citrate again. During the cycle more ATP is produced and electrons and other species are sent into the Electron Transfer Chain where most energy is generated. During this cycle three major events occur: 1. During the various transformations of Citrate, specifically when Succinyl-CoA is converted to Succinate, one Guanosine Triphosphate group (GTP) is generated, which then donates a phosphate to Adenosine Diphosphate (ADP) to create the energy molecule Adenosine Triphosphate (ATP). 2. Over the whole cycle, three molecules of Nicotinamide Adenine Dinucleotide (NAD) are reduced to NADH that donates its electrons to the electron transport chain that is responsible for the generation of large quantities of ATP. 3. A molecule of Flavine Adenosine Dinucleotide (FAD) is reduced to FADH2, again donating its electrons to the electron transport system and the generation of energy. Factor 2 and 3 are of more significance to energy generation than factor 1, and are the major means by which the Krebs Cycle generates energy. Electron Transport Chain The Krebs Cycle takes place within the mitochondria, structures that are contained in each of your body cells. Also within these mitochondria are a series of membranes that are very important in the generation of energy. The major energy produced in your body cells comes from the Electron Transport Chain, a series of chemical reactions between an electron donor and an electron acceptor. Such reactions drive the transport of hydrogen ions (H+) across the membranes in the mitochondria. The electron donors are species such as NADH, FADH2 and succinate and the electron acceptors are oxygen molecules. Hence the importance of oxygen in the process of aerobic respiration. The H+ ions are driven across the membranes and result in the conversion of ADP to ATP energy. In essence, the hydrogen atoms and electrons take part in a progressive chain of redox reactions, and at the end react with oxygen molecules and change it to water. The Ultimate Products Ultimately, through the whole chain and cycles of: Glucose to pyruvate (glycolysis) Pyruvate to Acetyl CoA + CO2 (oxidation) Acetyl CoA to Citrate and the entire Krebs Cycle (reduction and oxidation) Krebs Cycle products to the Electron Transfer Chain Electron Transfer Chain to Water and ATP (redox) Final oxidation of hydrogen atoms to water Basically: Glucose + Oxygen + 30ADP = Carbon Dioxide + Water + 30ATP This is not balanced of course, and the ATP could be anything from 29 to 38, though 29.85 is the most accurate calculation to date. The entire process of glycolysis, oxidation, Krebs Cycle and Electron Transport Chain is powered by a series of enzymes and a small amount of ATP energy. Glucose and oxygen are used up as the raw materials and ATP energy molecules are the product. It has been calculated that the total ATP yield obtained from one molecule of glucose lies between 29.5 and 30 molecules of ATP. The Importance of the Krebs Cycle to Your Body Were it not for the Krebs Cycle you would not be able to generate energy efficiently from your food. In particular, the carbohydrate content of your food. Carbohydrates are available in your diet from two sources: simple and complex carbohydrate foodstuffs such as cereals and grains, and fats and oils from animal and vegetable sources. They are also available from proteins, which are composed of amino acids at the head of the molecule with a carbohydrate tail. Carbohydrates by definition contain only carbon, hydrogen and oxygen molecules, and can be converted to glucose within your body. Proteins can be deaminated and then the carbohydrate portion again converted to glucose. In fact, your body will initially use the carbohydrates in your diet as a source of glucose for its glycolysis to pyruvate, then the fatty tissue in your body, then the proteins will be deaminated so your body can get to the carbohydrate they contain. Were it not for the Krebs Cycle, your body could not use the glucose as described above to generate energy. The only option open to it would be anaerobic respiration, or energy production in the absence of oxygen. ATP is still generated, but much less efficiently. Anaerobic Respiration Anaerobic respiration is basically respiration without oxygen. If there was no Krebs Cycle, then this is the only way your body would have to create energy. Because no oxygen is actually needed for glycolysis or the Krebs Cycle, anaerobic respiration can proceed right to the end of the Electron Transport Chain. Then instead of oxygen being used as the terminal electron donor, it has to be another species such as nitrate or sulfate. Because the Reduction Potential of these species is much lower than that of oxygen, the amount of ATP energy produced is also much lower. Your body tries to compensate by producing even more pyruvate and the excess is removed through lactic acid fermentation. Although this also generates ATP energy enough for short-term use, it leads ultimately to lactic acidosis and a reduction in pH, causing pain and vomiting. Ultimately, if oxygen is not forthcoming, the brain runs short of the energy needed for it to work and you die. There is insufficient ATP generated from anaerobic respiration to maintain human life. Conclusion The Krebs Cycle is of critical importance for the production of energy: not just the energy to enable you to run fast, but to enable your metabolic processes to continue. It is needed for both aerobic and anaerobic respiration, and while lactic acid fermentation can be used by your muscle cells as a brief but effective means of generating short-term energy, it is insufficient to maintain the needs of your metabolism. Without the Krebs Cycle, mammalian and most other animal life would not be viable and the world would be populated by anaerobic bacteria.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2217) Melatonin, What is it, Sleep And How it Helps!
Date:
December 22, 2010 03:20 PM
What is Melatonin?Melatonin, or N-acetyl-5-methoxytryptamine, is a hormone secreted during the hours of darkness by the light-sensitive pineal gland located in the brain and also by bone marrow, epithelial cells and lymphocytes. Melatonin plays a role in the human circadian cycle because of the fact that it is secreted only when it is dark. It can therefore be used to treat sleeping disorders, although it also affects conditions such as fibromyalgia and depression. Melatonin is also a powerful antioxidant, particularly protecting the DNA from free radical oxidation and studies have indicated a potential application in inhibiting the aggregation of amyloid beta protein in the brain that promotes Alzheimer's disease. It not only reduces the production of cholesterol in the gall bladder, but also increases the rate of conversion of cholesterol to bile, thus reducing the amount available for oxidation in the arteries that leads to atherosclerosis. A melatonin supplement is also believed to be an effective treatment for migraine and helps the gall bladder to expel gallstones, rendering them less likely to become a problem.
Melatonin and SleepMelatonin is a hormone that is secreted mainly by the pineal gland, a small pea-sized gland in the brain that is sensitive to light in that it secretes this hormone only during the hours of darkness. For this reason, melatonin can be used to help people sleep earlier and awake earlier, by shifting the circadian cycle to an earlier time. An interesting factor learned from the effect of light on melatonin is that it is suppressed only by blue light (460-480 nanometers) and by wearing blue filtering glasses it is possible to achieve the same effect as taking a supplement of the hormone. That is, to sleep earlier and waken earlier. People suffering jet lag, or who have to adapt to differing shift work patterns, benefit by taking melatonin, and it has also been used in helping with benzodiazepine withdrawal and helping people to stop smoking. You must let your doctor know you are using it, and in many countries it is available only by prescription.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2212) Free Radicals and how to Combat Them!
Date:
November 30, 2010 02:41 PM
Vitamin C and EChances are you have heard about antioxidants. They’re everywhere: in the news, on the internet, and, of course, in our body. The first group of antioxidants that spurred the war against free radicals are Vitamin C and Vitamin E. As early as the 15th century, seafarers knowingly consumed citrus fruits in treatment of scurvy, which today we refer to as a disease caused by a deficiency of Vitamin C. On the other hand, intake of green leafy vegetables results in healthy cells in the body, touted lately as one of the benefits of Vitamin E. Since the latter half of the 20th century the term antioxidants have come into wide use, sparking a series of studies that led scientists and health professionals to a much more well-informed understanding of how important these vitamins are to human life. Antioxidants and Free Radicals Two things about biochemistry that have been a part of our growing concern about eating right are antioxidants and free radicals, which you might have learned outside the classroom. The human body deploy free radicals for the purpose of killing harmful microorganisms, but somehow these chemical entities get out of control. It should be noted that most known free radicals are short-lived, explaining how we survive as they are toxic to the body. When not properly disposed of, free radicals are one of the reactive oxygen species that create a chain reaction damaging everything, including DNA. The problem arises when the body fails to detoxify these reactive oxygen species, and then the latter run amok inside the body. This is when antioxidants come into the picture. Vitamin C, Vitamin E, and Peroxyl Radicals Vitamin C and Vitamin E are lipids that protect the interior of cells from the outside environment and play a role in storing energy for use by the human body. Different groups of lipids encompass several major chemical reactions in the body, including securing the proper functions of physiological communication lines. In a process called lipid peroxidation, peroxyl radicals go on a killing spree by depriving the lipids of electrons, which continues as they bring in more radicals. The human body make use of Vitamin C and Vitamin E to police the proliferation of lipid radicals in time to deactivate lipid radicals and avoid unwanted effects on cell membranes. Ascorbate and Tocopherol as Co-Antioxidants In chemical reactions, the body utilizes forms of tocopherol in Vitamin E and ascorbate ions in Vitamin C. These antioxidants work on the principle of pairing with peroxyl radicals, taking on radical forms, ascorbate and tocopherol, to stop the oxidation process initiated by free radicals. At the molecular level, ascorbate makes an ideal antioxidant as it does not react with oxygen and terminates harmful peroxyl radicals that continue to oxidize. Studies say that Vitamin C and Vitamin E are co-antioxidants in that ascorbate works with tocopherol. For example, when continuing oxidation damage lipids, tocopherol, Vitamin E, removes the harmful radicals, and ascorbate recycles Vitamin E back to its usable tocopherol form. The Perfect Match Alpha Lipoic Acid recycles both Vitamin C and Vitamin E because alpha lipoic acid is both water and fat soluble.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2198) Vitamin A, C, E as Antioxidants
Date:
September 12, 2010 06:20 PM
Vitamin A,C,E can boost health Vitamins A, C and E are known as the antioxidant vitamins, and as such they play a role in protecting your body from the effects of oxidative stress or damage by free radicals. They also play other functions, such as the supporting role Vitamin A has with respect to your immune system, but as a general class they are used very much for their antioxidant properties.A consequence of this is that they should be included in your diet to protect you from damage to your arteries through the effects of atherosclerosis. This is a condition brought about by the free -radical oxidation of LDL cholesterol in your arteries leading to deposition of cholesterol plaques. These plaques progressively block up your arteries until they are so narrow that a small blood clot will block an artery, potentially causing a stroke or even heart failure.
Vitamin A, C, E
In order to prevent this, it is advisable to take a vitamin supplement containing Vitamins A,C and E. This will help protect you from strokes and heart disease caused by narrowing of the arteries by destroying the free radicals that cause it.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2187) Atherosclerosis and Policosanol
Date:
July 31, 2010 02:18 PM
Policosanol has been proposed as a treatment for a condition known as atherosclerosis, and prior to discussing the supplement and how it works, we shall first discuss the condition and what causes it. Cholesterol has a bad name, yet without it you could not live. Among its uses are the formation and maintenance of cell membranes, the production of hormones such as testosterone, its use by the liver as a raw material for bile and the metabolism of the fat-soluble vitamins, A, D, E & K. It also helps protect the arteries from damage. So cholesterol is necessary. However, it is only sparingly water soluble, and has to be transported by large fatty molecules that are also water soluble: low density and high density lipids (LDL and HDL cholesterol). LDL lipids generally carry cholesterol in the blood to the areas of the body where it is needed, while the HDL lipids carry it back to the liver for metabolizing. Free radical oxidation of LDL lipids causes them to deposit on arterial walls, and progressively block them leading to atherosclerosis. Even small blood clots can block the arteries leading to stoppage of the heart or strokes if the artery is in the brain.
Policosanol is a supplement, obtained in the USA from fatty alcohols extracted from beeswax and wheat germ, and in Cuba from other plant waxes, that is believed to reduce this problem and possibly even help to reduce the extent of atherosclerosis. HDL lipids can also reduce the extent of LDL arterial plaques. Studies are still under way, although the known side effects are only slight and many claim that Policosanol has improved their condition substantially.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2177) Glutathion, Antioxidants, And The Body
Date:
July 14, 2010 02:41 PM
Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges. Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis. A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids. The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell. Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion. Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well. Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2171) Antioxidants and your health
Date:
May 17, 2010 10:44 AM
There is an impressive amount of scientific evidence supporting the health benefits of supplementing with a wide variety of antioxidants. Consequently, there are many health practitioners who have begun to recommend high dietary intakes of these crucial nutrients in order to prevent against oxidative stress. It was anticipated over two decades ago by leading researchers that high-dose supplementation with antioxidants is developing a significant role in the prevention and treatment of a lot of today’s common illnesses. It should be noted that antioxidants do not work in isolation. When an antioxidant neutralizes a free radical, it, itself, is oxidized and must be regenerated by another antioxidant before it can be used again. Because of this, it is crucial to supplement with a wide variety of antioxidants, in order to reflect what actually occurs in nature. Vitamin C, an aqueous-phase antioxidant, is the main guard against oxidative attack in the extra-cellular matrix, as well as within the cytoplasm of the cell. Vitamin C happens to be a substrate for eight different enzyme systems that are involved in various cellular functions. Among these functions are collagen synthesis, ATP synthesis in the mitochondria, and hormone biosynthesis. Its main antioxidant partners are vitamin E and beta carotene, both of which help to regenerate vitamin C. Of all the antioxidants, it seems as if vitamin E offers the greatest protection against heart disease because of its ability to protect the cardiovascular system from oxidative damage. It is lipid-soluble, making it an important component of the cell membrane, where it works to protect the cell against lipid peroxidation and control oxidation-induced inflammatory events. Recently, the gamma tocopherol form of vitamin E has shown a great deal of promise in its ability to reduce the risk of several oxidative stress related disease. Beta-carotene is a member of a diverse group of photosynthetic pigments. It plays a huge role in human nutrition. As an antioxidant, it possesses a double-bond structure that allows it to react effectively with single oxygen radicals, absorbing and diffusing their energy. Beta-carotene also acts as a precursor for vitamin A by supplying a portion of the body’s requirement for the vitamin. This act alone plays a central role in the chemistry of vision. Beta-carotene and vitamin A both prevent the oxidation of cholesterol, reduce oxidative damage to DNA, and disable oxygen free radicals that are produced by exposure to sunlight and air pollution. These antioxidants are also involved in the activation of gene expression and the control of cell differentiation. When combined together, vitamin C, vitamin E, and beta-carotene produce and important antioxidant trio that plays a huge role in fighting oxidative and inflammatory events. There are several other antioxidants that should be noted due to their ability to work synergistically with the vitamin C, vitamin E, and beta-carotene trio. These include vitamin A, alpha-lipoic acid, lycopene, coenzyme Q10, and the antioxidant mineral, selenium. In order to determine whether a nutrient provides antioxidant support, scientists question whether the product contains vitamin C, vitamin E, vitamin A, beta-carotene, alpha-lipoic acid, lycopene, coenzyme Q10, and selenium and to what strength these vitamins and minerals are per serving.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2160) The Good and Bad of an iron supplement
Date:
April 25, 2010 06:04 PM
Iron holds a crucial role in the physiology of the body. It is a central part of the haemoglobin and myoglobin molecules. Iron is indispensable to the body’s ability to transport gases into and out of the cell. It is necessary in many important enzymes that are involved in energy production, metabolism, and DNA synthesis. Some iron is lost when red blood cells are broken down and excreted in the bile. However, because of iron’s importance, the body is able to conserve iron at all costs, as the kidneys do not eliminate the metal. The dark side of iron supplementation comes when iron is consumed in amounts that are excessive to the body’s needs. Although unbound iron is more likely to cause oxidative challenges through the generation of free radicals, excessive iron supplementation in any form can cause huge problems for the cell. The overload of iron can cause deterioration of the gut lining, vomiting and diarrhea, abdominal and joint pain, liver damage, loss of weight, and intense fatigue. In children, acute doses as low as 3 grams can cause death. About one out of every 250 North Americans suffer from haemochromatosis, which is a genetic defect that is common in a lot of those people of northern European descent. This disorder causes the body to accumulate and abnormally store high levels of iron. Those people with haemochromatosis store twice as much iron as others, which places them at increased risk for iron-related diseases. Symptoms of these diseases generally occur after fifty years of age and often include things ranging from fatigue, abdominal pain, achy joints, impotence, and symptoms that mimic diabetes. Several studies have produced evidence which suggests that high levels of iron contribute to noticeable increases in the risk for cardiovascular disease. This is likely due to non-haeme iron’s aggressive pro-oxidant nature. Iron levels are one of the strongest biochemical markers for the progression of atherosclerosis, which results from increased oxidation of LDL cholesterol. A study in 1995 conducted on Finnish men found that those who had high body stores of iron also had a substantially increased risk of heart attack. Those men who posses the highest levels of stored iron often showed a levels of risk that was up to three times that of men who possessed the lowest levels of stored iron. Disorders in iron accumulation contribute to a whole host of other disease states, all of which are degenerative in nature. Studies have shown that chronic iron overload contributes to increased infections, cancer, arthritis, osteoporosis, diabetes, and various congenitive dysfunctions. The only way to remove excess iron is through blood letting, unless you are a woman with regular menses. That is why, for men, iron overload can provide quite a problematic issue. Recent research has found that long-term supplementation with iron at doses less than 5 mg/day can lead to iron-overload toxicity. Because of this, it is recommended that the upper limit of iron intake be at 5 mg/day when considering a product’s rating. Any product that contains iron at a daily dose greater than this limit is penalized with this rating criterion. But for those who need iron, it can easily be obtained through a vitamin supplement at your local or internet health food store. Men should avoid iron supplements and products containing iron, but women on the other hand due to monthly blood loss should supplement with iron regularly.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2157) NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE
Date:
December 10, 2009 04:23 PM
NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE™NADH is the biologically-active form of vitamin B-3 (niacin), and is involved in a wide range of functions throughout the body. An easier way to understand it, is to think of NADH as a biological spark plug that makes it possible for us to become and remain energetic, active, and functioning at our best. Remove the “spark” and some of the most basic human functions will inevitably suffer. This is not speculation. It is the result of decades of scientific investigation that has examined the link between nutrition and chronic conditions; notably those related to cellular life cycles and apoptosis, excessive fatigue, enzyme decline, free radical expansion, cognitive disparity, intracellular balance, normalized aging, and many more important aspects of human health.* Based on a wealth of ongoing studies, we have a great understanding of the benefits of NADH. Not only is it an effective source of cellular energy, it is also one the body’s versatile electron donors—the molecule most frequently degraded during oxidation. Because of these characteristics NADH is, however, also very unstable with regard to light and oxygen, which leads to a very rapid loss of overall effectiveness. Additionally, poor lifestyle choices, such as the use of tobacco, excessive consumption of alcohol, drugs, and prescription medications, sleep deprivation, genetically-engineered foods, and a host of others can all inhibit the activity of NADH within the body. Hope is not lost, however. NOW® NADH contains a patented form of NADH from Panmol® - the first natural stabilized, stomach acidresistant form of this unique vitamin B3 supplement. Panmol® uses a patented process to naturally preserve its effectiveness. The end result is a highly stable, and bioavailable NADH which can easily withstand the harsh, acidic environment of the stomach and digestive tract; a breakthrough in the battle against many of todays’ most chronic conditions. NOW® NADH is available in both 10 and 20 mg potencies. Both varieties have been further enhanced with 200 mg of Bioenergy RIBOSE™ to support its cellular energy support properties.* Who Stands to Benefit from NADH With a proper supply of amino acids and/or B3 vitamins (niacin) the human body is, in fact, capable of producing a limited reserve of NADH. Under chronic strain however, the body’s need for NADH increases. As we age, the body’s ability to manufacture NADH becomes increasingly limited. With this in mind, the following groups stand to benefit the most from incorporating NOW® NADH into their supplement regimen.
• Those who work in stressful, cognitively-demanding professions
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2115) L-Cysteine
Date:
May 08, 2009 10:00 AM
L-Cysteine is what is known as a non-essential amino acid, meaning that it can be biosynthesized by the body and hence not an essential part of your diet. Due to its possessing a thiol side chain, it is termed a hydrophilic amino acid with an affinity for aqueous systems. Because of this it is relatively highly reactive, and is therefore an important component of a large number of enzymes and proteins. Although, after all, it is not an essential amino acid, deficiencies can occur in the young and in the old, and also in those suffering certain metabolic diseases. Dietary sources include high-protein foods such as chicken, turkey, pork, dairy products and vegetables such as cereals, broccoli, garlic and onions. The biochemistry of this amino acid begins with another amino acid known as serine, and also methionine. The latter is fist converted to homocysteine, which is then combined with serine to form cystathionine. This is then converted into cysteine and alpha- ketobutyrate. The thiol group is highly reactive and gives cysteine its biological properties. L-Cysteine possesses strong antioxidant properties due to the thiol group which easily undergoes redox reactions. However, it is for its detoxification effect on the body that the amino acid is mainly taken as a supplement. It is, therefore, these properties that we shall discuss first. Cysteine can reduce the toxic effects of alcohol, such as a hangover or the more serious liver damage. The by-product of alcohol metabolism that does most damage and is responsible for the majority of the negative after-effects of excessive alcohol consumption is acetaldehyde. L-Cysteine converts acetaldehyde into the more acceptable acetic acid, and so prevents the aldehyde from having too much of a negative effect on your health and well-being. However, the results obtained from such studies have been from animals only, and the therapeutic effects of cysteine have not yet been tested on humans. What has been tested and is known is that L-cysteine is effective in the detoxification of heavy metals in the body. A common source of heavy metal toxicity is mercury from amalgam fillings in the teeth. Although the Environmental Protection Agency (EPA) declared in 1989 that dental amalgams are a hazardous substance under the Superfund law, many people still have them in their mouths. The thiol group and L-cysteine has a high affinity for mercury and other heavy metals, as previously stated, and a supplement can be used to remove from the body any mercury leached from mercury-based tooth fillings. It can also be used to bind to copper, lead and cadmium. Lead and cadmium are particularly toxic to the human body, and even though lead is no longer used in plumbing or paints, and cadmium in toys or paints, there are still many sources of these two heavy metals available that can lead to human toxification. An L-cysteine supplement can be used to remove these heavy metals from the body. Any proteins containing cysteine will tightly bind heavy metals such as lead, cadmium, molybdenum, cobalt and mercury, and allow them to be excreted by the body in the usual fashion. This direct involvement in heavy metal detoxification is a very useful property of this amino acid. Another detoxification application of L-cysteine is in direct involvement in protecting cellular glutathione levels, and also the prevention of the death of liver cells by acetaminophen poisoning. The latter is of particular interest to many people since acetaminophen is better known as paracetamol, and since this is a freely available over-the-counter drug, overdoses are not unknown. The result of an overdose is the necrosis of liver cells, with eventual liver failure and death. The treatment of choice is N-acetylcysteine. If used within 10 hours of the overdose it is extremely effective, and even from 16 to 24 hours it is better than other controls. It is believed that the acetylcysteine liberates cysteine which, when available to the liver, enables the biosynthesis of glutathione. Glutathione can then maintain the production of the fifth metabolite required for the specific detoxification of the paracetamol/acetaminophen. L-Cysteine is also an essential component in the biosynthesis of coenzyme A, an enzyme essential for the production of energy from fats and carbohydrates. It is also a very important component of hair, from which it is commercially produced. Without an adequate intake of L-cysteine the growth of healthy hair would not be possible. There are several supplemental uses of L-cysteine including the treatment of bronchial conditions for which the amino acid can help to liquefy and clear mucus from the airways and lungs. It is also used to protect against side effects of chemotherapy treatment of cancers and for medical treatments for excessive exposure to radiation. However, there are certain situations in which L-cysteine should be avoided when at all possible. Diabetics should not use it, and neither should those suffering from cystinuria, whereby large quantities of amino acids, including cystine, are excreted in their urine. L-cystine, incidentally, is formed by oxidation of L-cysteine. Paradoxically the amino acid is one of the several hundred additives made to tobacco by the cigarette companies. Although, as with the majority of tobacco additives, its purpose is unknown there are two possible reasons for its inclusion. L-Cysteine is a known expectorant, so it could be added to promote the expectoration of mucus in the lungs which is promoted by smoking, and it also increases the production off the antioxidant glutathione that is depleted in smokers. There are several other non-medical uses for the amino acid, but it is for is its detoxification properties that it is most used as a supplement. However, because it is largely derived from human hair or duck feathers, it may not be classed as kosher or halal in spite of many claims made to that effect, though the more expensive source of microbial fermentation from corn sugar can be. The substance is recognized as safe by the FDA, and must be labeled as L-cysteine when it is present in a preparation intended for its therapeutic effects. Keep in mind however, that it should be avoided by diabetics.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2005) L-Carnitine
Date:
May 07, 2009 05:45 PM
L-carnitine is amino acid essential for the metabolism of fats into a form of energy necessary for extended aerobic activity. Originally discovered in Russia, and Germany a year later, the structural formulation of carnitine, as it is correctly known, was determined in 1927, although it is physiological and biochemical activity was not understood until the 1960s. The amino acid is biosynthesized in the liver and kidneys from lysine and methionine. The vitamins niacin, B6, C and iron are essential for this reaction to take place. However, the supply of L-carnitine has to be supplemented by the diet, good sources being dairy products, red meat, nuts and seeds, pulses and fruits such as apricots, bananas and avocado. Most of the L-carnitine supply of the body is stored within the muscle tissue. However, it is not unusual for conditions to arise making it difficult for the body to obtain all the carnitine required. L-carnitine enables fatty acids to be transported into the mitochondria, where cell metabolism occurs. The biochemistry is discussed below, although in simple terms the amino acid allows body fats, in the form of triglycerides, to be made more readily available for the generation of energy required for extended exertion. In this way, body fats can be used for energy and the supplies of glycogen stored by the liver can be retained for emergency use. By providing the energy for endurance and stamina in this way, carnitine makes use of an otherwise unavailable energy source, and has the added benefit of reducing body fat stores and reducing strain on the heart. Although there is generally a plentiful supply of L-carnitine available in a healthy diet, supplementation can ensure that a deficiency does not occur. Supplements are available in the form of L-carnitine or its acetylated derivative, acetyl L-carnitine. In order for fatty acids to be used in the production of energy, their long-chain acetyl groups have to get inside the mitochondria where they are oxidized to the acetate to be used for the production of energy via the Citric Acid or Krebs cycle. In order for the biochemistry to take place, fatty acids must be rendered suitable for binding to the carnitine molecule. The chemical grouping with a good affinity for L-carnitine is the acetyl or acetyl group, available in the molecule acetyl coenzyme A (CoA). The free fatty acid, therefore, is attached to coenzyme-A by means of a thioester bond, catalyzed by means of the enzyme fatty acetyl-CoA synthetase. The reaction is then completed by means of in organic pyrophosphatase. In this way, the fatty acid in the form of an acetyL-carnitine derivative can be transported through the mitochondrial wall. This transportation takes place by means of several steps. These are: 1. As explained, the acetyl-CoA is attached to L-carnitine by means of the enzyme carnitine acetyltransferase I. This enzyme is conveniently located on the outer mitochondrial membrane. 2. The enzyme carnitine-acetylcarnitine translocase helps the acetyL-carnitine through the membrane. 3. Another enzyme, carnitine acetyltransferase II, located on the inner mitochondrial membrane, converts the acetyL-carnitine to acetyl-CoA, liberating the carnitine which returns to the muscle mass. L-carnitine is the only known substance that allows fatty acids to cross the mitochondrial membrane, and therefore deficiencies must be avoided. Another way in which carnitine is used in energy production is in the Krebs cycle itself. Part of this cycle involves the conversion of guanine diphosphate to the higher energy form guanine triphosphate. In this way energy can be stored in much the same way as it is in the conversion of ADP to ATP. Succinyl CoA is involved in this conversion, and one of the by-products of it is a corresponding succinate, that is then converted to a fumarate by the action of L-carnitine fumarate. Carnitine, therefore, has two parts to play in the production of long-term energy from the fatty acids contained in body fats. Since the fatty acid triglycerides contained in body fats are a major source of energy in the heart and skeletal muscles, it is easy to understand how L-carnitine is believed to lead to the increased energy levels required for stamina and staying power. A major reason for its effect on longer-term or extended energy requirements is that in enabling stored body fats to be used for immediate and longer-term energy requirements, L-carnitine allows emergency glycogen stores to be retained for use once immediate fatty acid supplies or those of carnitine have been depleted, and so allows the energy supply to be extended even farther. Research has also suggested that the amino acid can possibly be used to treat liver and kidney disease, diabetes and chronic fatigue syndrome. As with many supplements, the question is often asked how does L-carnitine work in practice as opposed to the claims made for it by the supplement providers? Recent research indicates mixed results, but sufficient to justify its use. It is generally accepted that a supplement is necessary when there is a deficiency, but once that deficiency has been corrected further intake is unnecessary. However, it is also believed that during long and extended periods of exercise a carnitine deficiency does occur as L-carnitine is used up, and the supplement is necessary to ensure sufficient energy supply throughout the period of exercise. There has also been a case reported in the Journal of Clinical Neurology (Negoro, Tsuda, Kato & Morimatsu, 1995) where a deficiency, caused by anorexia nervosa damaging the liver to the extent that it was unable to synthesize L-carnitine, was remedied by means of an oral supplement. Studies on endurance athletes have been mixed, ranging from no effect to L-carnitine being found to promote weight loss. Carnitine has no unknown harmful side effects, and has been studied for medical applications other than as an energy supplement. For example it possesses extensive antioxidant properties, and can be used as a supplement against oxidative stress and the prevention of the lipid peroxidation that is a precursor to atherosclerosis. Its use in osteoporosis and reducing bone mass is also being studied. The concentration of L-carnitine diminishes with age, and affects fatty acid metabolism in a number of tissues. Bones are particularly affected since they require continuous reconstruction. Without detailing the biochemistry involved in this, administration of carnitine helps to reduce the speed by which this occurs. Trials are so far been carried out only on animals. In studies on both healthy volunteers and patients with type II diabetes, L-carnitine was found to improve storage of glucose in both groups, although its oxidation increased only in the group with diabetes. Other studies carried out include improving the function of neurotransmitters in the brains of elderly patients and in the treatment of Alzheimer's and Parkinson's disease, and other neurological disorders. In conclusion then, although the jury is out on the use of L-carnitine is an energy-giving or weight-loss supplement, it appears to be effective where the body's stores of carnitine could be depleted such as with long-term exercise, natural deficiencies or deficiencies caused through age. It is also under study in the treatment of various medical conditions. On balance, it would appear that the prospective benefits of L-carnitine render it worthy of use.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2004) Protect The Liver with Glutathione And Cysteine
Date:
April 23, 2009 01:54 PM
The tripeptide L-glutathione is synthesized in the body from L. glutamic acid, L-cysteine and glycine, a reaction that can occur in any cell of the body although it is essential that it also occurs in the liver. Should glutathione concentrations drop, they can be increased by supplementing with cysteine or any other of the three amino acids that are used in the biosynthesis of this important if substance The tripeptide exists in two forms: the reduced form (GSH) which contains a sulfhydryl (SH) functional group attached to the cysteinyl part of the molecule, and the oxidized form glutathione disulfide (GSSG). As electrons are lost from the reduced form, two molecules combine to create a dimer formed by a disulfide bridge, the process which can be reversed through reduction of the GSSG. Such electrons are lost during its reaction with free radicals, in which the free radicals are neutralized by the donation of an electron from the oxidized version of glutathione. The definition of a free radical is a molecule that is lacking one electron from an electronic pair. Its prime purpose is then to steal an electron from the nearest molecule to it. In doing so, it can not only destroy that molecule, but also destroy body cells and lead, not only to premature aging, but also to some potentially fatal conditions. It is an unusual peptide in that it involves a link between the cysteine amino grouping and the carboxyl functional group of the glutamic acid. It is a powerful antioxidant, acting as an effective free radical scavenger and protecting the body cells from the effects of free radical oxidation. However, it is on its detoxification effect in the liver that we shall focus here prior to discussing some other uses to which the body puts glutathione in its two manifestations. Much of the detoxification is connected with the thiol group in the molecule. Take mercury for example. The thiol grouping forms a strong Hg-sulfydryl chemical bond within the liver, in the form of a glutathione-mercury chelate. In this form mercury is unable to exert any toxic effect on the body and can be excreted in the normal manner. The same reactive pathway is followed by other heavy metals that can bond to thiol groupings. In this way L-glutathione can protect the liver from the effects of a number of toxic heavy metals such as cadmium and chromium. This is an important property of the amino acid, particularly in industrial and urban environments where the population is more prone to exposure to heavy metals than their rural counterparts. However, the end result on the glutathione is that it is removed from the body, and, particularly with city dwellers, a supplement may be required to maintain a healthy concentration of this amino acid in the body and in particular in the liver. Therefore, although L-glutathione is not considered an essential amino acid, in that it is biosynthesized within the body, a supplement is sometimes required, particularly by those who live in large cities. It is important to consider the form in which the glutathione supplement is administered. This is because of the presence of gamma-glutamyltranspeptidase within the digestive system. This enzyme appears to destroy L-glutathione before it can be absorbed in the intestine so normal oral forms of supplementation are likely to be ineffective. Possible forms of effective administration include buccal (between the cheek and teeth) and hypodermically. An alternative means of supplementation is to take substances such as selenium, methionine, alpha-lipoic acid, vitamin C and glutamine that stimulate the biosynthesis of glutathione. Also, since the substance utilizes the raw materials of L-cysteine, glutamic acid and glycine in its intracellular production, supplementation with these amino acids should also help to produce L-glutathione. That said, let's return to its antioxidant properties and its effect on the liver that contains the largest stocks of glutathione in the body. It is generally regarded as the most important antioxidant in the body. It protects cellular cytoplasm from oxidation by reducing disulfide groups and maintaining a highly reducing environment within the cytoplasm. It reacts with hydrogen peroxide and other oxidative agents, and is converted to the oxidized form GSSG. It is then reduced back to GSH through the combination of the reducing agent and an enzyme. The reducing agent is nicotinamide adenine dinucleotide phosphate (NADPH), the enzyme being glutathione reductase. The implications that this strong reducing effect has on the liver are significant. Reduced GSH L-glutathione levels have been found in patients suffering from HIV, hepatitis C and other liver diseases. Supplementation with GSH has been found to restore normal levels of glutathione to the liver, and it has been demonstrated that the treatment has improved such conditions significantly. Atherosclerosis is a condition of the arteries caused by the deposition of plaques formed from oxidized low-density lipoproteins, otherwise known as bad cholesterol. The strong antioxidant effect of GSH prevents this from LDLs from being oxidized and deposited on the arterial wall. There are other results of glutathione supplementation that indicate the effectiveness of antioxidants in the treatment of serious liver conditions, and there are no doubts that combating the effects of free radicals and oxidizing agents within the liver has a positive effect on many potentially serious liver diseases. Many of these are exacerbated by the generation of free radicals by relatively modern pollution sources such as pesticides, petrol and diesel emissions, tobacco fumes and various other chemical emissions. A strong antioxidant such as L-glutathione cannot be anything other than an effective means of reducing the biological effect of these oxidants. It protects not only the liver but also the lungs and cardiovascular system. For all these reasons a supplement consisting of L-glutathione or its constituent parts, glutamic acid, cysteine and glycine, provide significant protection against the stresses and strains of modern living. Increased pollution levels and heightened oxidative stress levels within the body are playing havoc with our body defenses, and GSH is an important one of them that can easily be enhanced by supplementation. There are no known reactions to L-glutathione supplementation, but pregnant women and babies should receive expert medical advice prior to taking it.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1996) Detoxify With L-Citrulline
Date:
April 13, 2009 03:51 PM
L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood. It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea. The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea. The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-hydroxyarginine, and then into L-citrulline with the release of nitric oxide. So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells. Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred. In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure. Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery. During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow. It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels. It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid? Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise. Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted. Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.
L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1993) Guarana Seed Extract
Date:
November 17, 2008 11:24 AM
Guarana comes from the Amazon basin, and has been used by the natives of the Amazon rain forest to treat conditions such as diarrhea, arthritis, fatigue and even to reduce hunger. It is, in fact, a climbing plant of the Sapondacaea family, although it is the fruit for which it best known. Each contains a single seed that contains around five times the amount of caffeine of a similarly sized coffee bean. An interesting piece of trivia is that the reason why such seeds are rich in caffeine is that the substance is poisonous to certain pathogens that would otherwise attack the berry. The same is - true of all seeds that contain caffeine: it is a means of self-defense. Obviously it is an effective defense since the berries appear to relatively immune to such common plant diseases. Guarana is named after the Guarani tribe of South America, and the language is spoken by many in the area around Paraguay, Bolivia and Brazil, and also parts of Argentina. In fact over 67% of Paraguayans speak the language. There is a myth that when child of the Guarana village was killed by an evil god, a more benevolent deity planted the child's left eye in the forest and the right eye in the village. The left eye gave rise to the wild form of the plant, and the right eye the cultivated form. This likely came about because of the appearance of the fruit when it is split open: it has the appearance of eyeballs. However, what is true is that Guaranis made tea from the seeds, and also a bread known as guarana bread by mashing the powder into a dough and shaping it into a cylindrical bread. It is dry roasted and milled to a fine powder, also known as Brazilian cocoa, but it has never quite managed to compete commercially against the coffee! However, it has its local adherents to whom it is a staple drink. However, back to the health benefits of the seed. They were recognized as early as the 17th century when Father Felip Betendorf introduced it into Western civilization, but over the centuries since then it has been found that even in spite of the caffeine content it has been demonstrated to have brain-boosting properties and able to increase tasks requiring mental attention. It is certainly known to be an energizer, and able to give a boost to your brain when you really need it. So why should this be, and how does it do this? The flavor is a bit like chocolate, hence its nickname of Brazilian cocoa, and has been approved by the FDA as a food additive. Extracts from the berry have been shown to possess strong antioxidant properties, and also act as bactericides and fungicide, few of which can be put down the caffeine content. In fact the seed has been proposed for use in the food industry as a natural antioxidant and preservative and as stated below, that is more acceptable to people than synthetic chemicals. This is probably in response to the fact that synthetic antioxidants are in decline whereas the natural antioxidants such as vitamins, C and E and the various tocopherols and carotenoids are increasing in prominence due to them being more readily accepted by the consumer than the synthetics such as butylhydroxytoluene(BHT). These antioxidants are commonly used as food preservatives, in that they slow down the oxidation of foodstuffs, and people are increasingly feeling that natural products are preferable for this application than synthetic. Guarana seeds have been found to be exceptionally high in proanthocyanadins with powerful antioxidant properties. They are fatal to free radicals and help to prevent cardiac disease and to improve cellular activity. They also display antimicrobial and antifungal activity. Chemically, they consist of up to 60% starch, pectins, saponins, proteins, and the aforementioned caffeine (3% - 5%). The guarana paste can contain up to 7% caffeine that can be dangerous to those with cardiac problems. Guarana also contains tannins at levels of up to 12%, including catechin and some proanthocyanadins. The astringency of these tannins represents a problem to their use in the beverage and food industry, although the substance is regarded as safe by the FDA. They have little if any nutritional value and can react with alkaloid and proteins to form unwanted complexes. Were it not for tannins guarana would be more acceptable to the food industry. However, it is for their energy-boosting properties that the guarana berries and seeds are most prized by many. The fact they it has been traditionally used as a stimulant and aphrodisiac indicates that there is something behind these claims. Studies on mice, hamsters and other animals have supported these effects. It has been found to posses the two desirable properties (to some) of stimulating the nervous system and curbing the appetite. Consequently, it is used in diet and weight loss pills, and also to maintain high energy levels. In fact weight loss pills are used by many people to maintain their energy levels while not eating. This is a definite bonus to those that want to lose weight, but dislike the lethargy that a strict diet can cause. There is a downside to that of course, and that is insomnia and an increased heartbeat, and also nervousness and feeling 'on edge'. Once people stop using guarana they suffer withdrawal symptoms such as nervousness, irritability and headaches. The upshot is that it is basically the high caffeine content of guarana that allows its use as a stimulant that can boost not only energy, but also reduce appetite and act as an effective weight loss supplement. However, used excessively it can lead to nervousness and while it is included as an ingredient in many foods and drinks, you should be careful when using it as an energizing supplement if you have any heart problems at all.
Otherwise, guarana is used to energize the body naturally, and is not only very commonly used for this purpose in South America, but also increasingly so in the USA and elsewhere with some very good results.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1936) Guggul
Date:
November 10, 2008 10:30 AM
Guggul is a natural herb supplement that may help lower cholesterol, yet few in the Western hemisphere know much about it. Guggul is otherwise known as the Mukul myrrh tree, and is a plant of the Burseracae family with small red or pink flowers. It is found across central Asia over to North Africa, although is very common in the northern areas of India where the climate is more semi-arid than equatorial. Guggul does not like a lot of water and can thrive in ground where the soil has few nutrients. Its Latin name is Commiphora wightii, and it grows about 12 feet high. It has been predominantly used in the Ayurvedic medicine of ancient India, and like many such ancient remedies and treatments, is now used in modern medicine to treat specific conditions: conditions such as some forms of heart condition, where it has been found to be able to lower your blood cholesterol levels, weight loss and some forms of arthritis and other inflammatory conditions. However, it has been used so successfully over the years, particularly in India, which it is now in danger of extinction and is contained in the Red Data List of the World Conservation Union that lists endangered species. So what is so special about this plant that makes it so popular? To get the answer to that we have to go back a bit in its history, although not quite as far as the two or three thousand years that it is known to have been used in traditional Hindu medicine. The active ingredient is found in the sap of the tree, and is used to fight against obesity and other diseases that can be caused by excess weight or cholesterol, such as arthritis, obesity and atherosclerosis. Until recently it has had very little support for its claims from conventional medicine. It was in the 1960s that an ancient Sanskrit text was found that recommended guggul as a treatment for high cholesterol levels. Since that discovery, research has focused on the plant's anti-cholesterol properties, and a great deal of evidence has been gathered supporting the claims of that ancient text. So much so that the Indian government has approved the use of guggul for the treatment of high cholesterol levels, largely because it has been found very effective in reducing the levels of 'bad' LDL cholesterol in the blood while increasing the levels of the beneficial HDL cholesterol. Several trials have supported this, including one study involving 228 patients that showed the extract to be equally as effective as the anti-cholesterol drug clofibrate. That is not all, and other studies included one in which a decrease in LDL cholesterol of almost 13% was measured in a double blind study involving 61 subjects, of which around half received a placebo. An average 12.7% reduction in LDL cholesterol, 12% in triglycerides and 11.7% in total cholesterol was experienced by the group given the guggul extract. Every 1% drop in total cholesterol is associated with a 2% decrease in the risk of heart disease. Guggul reduces the levels of harmful cholesterol in your blood by converting it into bile. The plant extract contains substances given the name guggulsterones that block the activity of a protein that regulates the metabolism of cholesterol in your body known as FXR (the Farsenoid X Receptor). This protein can increase the risk of you contracting heart disease by preventing the liver from converting cholesterol into bile acids, so that the concentration of cholesterol in your blood continues to build up. The problem with bile acids is that once they reach a certain concentration in your body, the FXR comes into play and stops more being produced. Guggulsterones prevent the FXR from doing this, and so helps the liver to destroy more cholesterol. There is a reason for the body not allowing too much bile acid to be generated, but for those with excess cholesterol, it is more beneficial for this regulation to be prevented, and more cholesterol to be destroyed by the liver. It is the resin of the plant that is prized, being extracted from the bark in much the same way as rubber is tapped. It is also used in fragrances and perfumes in addition to its medicinal uses, and the dosage generally recommended is 1500 mg (1.5 grams) twice daily. However, it is not recommended for those suffering liver disease, irritable bowel syndrome, Crohn's disease or any form of diarrhea, and should not be taken by those on beta blockers. It is not only for its cholesterol-lowering properties that guggul is prized, however. Another property it possesses is its ability to render blood platelets less sticky, and so reduce the risk of coronary disease, and prevent the formation of blood clots and thrombosis. Another use it has found is in the field of weight loss, where it has been found effective in reducing the weight of obese adults. It does so by the activation of lipolytic enzymes and increased levels of triiodothyronine (T3), believed to be due to the formation of T3 from T4 (thyroxine) in the liver. T3 increases the metabolic rate, and the rate of the breakdown of glycogen and gluconeogenesis: the biosynthesis of glucose. It also causes cholesterol to be broken down and increases the rate of lipolysis - the breakdown of fats stored in fat cells in the body. Studies have shown that those taking guggul lost up to 6 times the weight of a control group within 15 days, and the practice is going along with the theory. Not only that, but when you are on a diet, your body is likely to respond by decreasing levels of triiodothyronine, and so reducing the rate at which fat burns. Hence, your diet does not help you top reduce weight as quickly as it could. Guggul, however, stimulates the production of T3, and so you are not only taking less fat into your body, but are also burning it up at an accelerated rate. Other uses to which the resin has been put are based upon its anti-inflammatory properties. It has been found to be an effective treatment for some forms of arthritis and also in the treatment of acne. The active inflammatory ingredient is believed to be myrrhanol A, a polypodane-type triterpene, which would also explain the antioxidant effect of guggulipid on lipid peroxidation.
Guggul is a versatile plant, and a good supplement to take for anybody suffering increased lipid or cholesterol levels, and who wants to increase the weigh-loss effect of their diet. However, make sure that you purchase a supplement standardized on its guggulipid content.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1933) Green Tea Extract
Date:
October 23, 2008 01:43 PM
Green tea is a form of tea made from the leaves of the Carmellia Sinensis, a shrub that is native to China and has spread to other areas of Asia including Japan and the Middle East. Drinking it is believed to impart many health benefits, including the prevention of obesity, heart disease and some forms of cancer and it has been used in traditional Chinese medicine for over 400 years. Tea is known to have been consumed in China for around 5,000 years, and used, not only in Chinese medicine, but also in that of Japan, Thailand and India for a number of ailments including regulating blood sugar, treating wounds and digestive problems. The drinking of green tea to benefit the heart and other vital organs is described in the Kissa Yojoki (Book of Tea), written in 1191 by Eisai, a Japanese Zen priest. This two-part book talks about the various medicinal benefits of green tea, such as preventing fatigue, curing beriberi, quenching thirst, clearing the thoughts, maintaining health of the urinary tract and improving digestive problems. It also explains how to grow tea and how to prepare and use the leaves. The methods of treatment of various ailments and medical conditions are described in the second part of the book. The active ingredients in green tea are catechins, polyphenols with strong anti-oxidant properties. Antioxidants are important components of your diet due to their effect on free radicals. These are small molecules, generally oxygenated, such the superoxide cation and hydrogen peroxide that are generated during normal metabolic processes and also ingested in pollutants such as traffic and factory fumes and insecticides. Free radicals are also formed by the effect of the ultra-violet component of sunlight on your skin and other tissues. The effect of free radicals on your body can be devastating, and they not only destroy cell membranes but also oxidize such molecules as the low density lipids (LDL) that carry cholesterol around your bloodstream. This allows the LDLs to be absorbed by the white blood cells and then deposited as fatty plaques in the walls of your arteries. The end result is a thickening and hardening of the arteries that leads to a condition known as atherosclerosis, where the blood supply to the brain and heart muscle is restricted, which can in turn lead to strokes and heart disease. Their effect on your cells is to cause cancer and premature aging, among others, and free radicals are also believed to play a part in conditions such as Alzheimer’s and Parkinson’s disease and also inflammatory diseases such as arthritis and diabetes. They can also cause damage to your DNA. It is essential, therefore, that these free radicals are destroyed as quickly as they are generated, and that is what antioxidants do. You might be more familiar with the antioxidants Vitamins A, C and E, and phytochemicals such as flavonoids and carotenoids, but there are many substances available to you that are even more powerful such as the polyphenols found in green tea. Epigallocatechin gallate (EGCG) is the most powerful of these with antioxidant properties at least twenty five times that of Vitamin E, and 100 times that of Vitamin C. EGCG comprises around 10-50% of the total catechin content of the tea and studies indicate that it likely helps to protect against DNA damage by free radicals, to protect against oxidation of LDL, provide protection against the damage of ultra-violet radiation and to protect you from the free radicals that are generated by smoking tobacco and general airborne pollution. There are suggestions that the bioavailability of EGCG can be increased by consuming black pepper when drinking green tea, possibly due to the presence of piperine in the pepper. The piperine appears to retard the intestinal glucuronidation of EGCG and so allow more of it to be absorbed as opposed to excreted. So if you are using green tea for health reasons, spice up your food with a small amount of black pepper - that's all it needs. You don't have to smother your food in it! It should be stressed that these tests were carried out on animals, although the biochemistry involved is much the same. The oxidation of fat by your metabolism to provide energy is a very important factor in weight control. If the contribution of the fats you ingest to the energy generated by your metabolism is low, then the fats can go on to be deposited in your body. This is not only unsightly, in that it can basically make you look 'fat', but is also dangerous to your health. Fat deposits around your midriff and round the major organs of your body can be extremely damaging and a severe risk to your health. It has been shown by a recent study in the UK (Birmingham University) that those taking green tree extract displayed a 17% increase in fat oxidation over those given a placebo. Not only that, but the ratio of fat oxidation to the overall energy expenditure showed a similar differential between the study and the control group. This provides evidence of green tea extract being able to control your weight by burning fat, and also to improve the tolerance to glucose and sensitivity to insulin of healthy people. Many other health claims have been made for green tea extract, although many of these have little, if any, scientific basis. Among these are the claims that it can treat multiple sclerosis and be used to treat cancer, although claims that it can prevent the destruction of cell membranes due to its oxidative effect are supported by the biochemistry, if not the medical proof. There are cases where theoretical biochemistry can explain many of the applications of ancient remedies without needing modern day studies to support it. Some of the research supporting the green tea theories include: 1. In 2006, a study was announced that had followed over 40,500 Japanese men and women, aged between 40 and 79, that had no history of coronary heart disease, stroke or cancer starting in 1994. It was found that those who drank at least 5 cups of tea per day had a 16% lower risk of dying from any cause and a 26% less risk of dying from cardiovascular disease than those that drank less than one cup of tea each day. Since cardiovascular disease and cancer are the major causes of death world-wide, these are significant results. 2. Again in 2006, it was reported in the American Journal of Clinical Nutrition that studies indicated that a higher consumption of green tea was associated with a reduction in human mental impairment when compared to the average. 3. Yale University School of Medicine reported later that year that, in spite of smoking more than their western counterparts, Asians suffered lower rates of cancer and heart disease, and put that down to them drinking over 4 pints of green tea daily. It was the polyphenol content of green tea and its antioxidant effect that was proposed for this result, known commonly as the 'Asian paradox'. A specific reason given for this was the antioxidant effect preventing the oxidation of LDL cholesterol, and its subsequent deposition in the artery walls. 4. Another component of green tea is the amino acid L-Theanine that promotes relaxation, and it is believed that this could help to fight stress by inhibiting the excitation of cortical neurons.
There is a lot more evidence for the health benefits of green tea, and once again it appears that the ancients have been proved correct. Perhaps we should pay more attention to ancient remedies, although without the proper evidence much of it is ignored - for the time being at least. Green tea, however, has generally been accepted due to the research and studies carried out on ECGC (Epigallocatechin gallate) and in additional to the traditional form, is also available as a dietary supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1923) Green Coffee Bean Extract
Date:
October 22, 2008 04:59 PM
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs. The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition. However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here. The Free Radical Theory of Aging Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them. Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging. Free radicals are generated in the body in four different ways: 1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher. 2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes. 3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting. 4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products. In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body. So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell. Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron. Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals. It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol. The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level. Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging. A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life. There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1922) Glycine
Date:
October 11, 2008 10:26 AM
The non-essential amino acid glycine is needed to generate muscle tissue and also for the conversion of blood glucose into energy. It is referred to as being ‘non-essential’ because the body can manufacture its own glycine, and is therefore not an essential component of your diet. Other uses to which glycine is put by the body includes the maintenance of a healthy nervous system, and is necessary for the proper functioning of the digestive system. Amino acids play three essential roles in the human body: 1. They are the building blocks of proteins: proteins comprise about half of the dry weight of the majority of your body cells, and without them there would be no life. They are produced using monomers known as amino acids, and there are about 20 different amino acids used to make the vast variety of proteins that make up the human body. Proteins are needed to form enzymes, the catalysts that permit the majority of chemical reactions within our bodies, and also genes, the building blocks of DNA. 2. More relevant here, amino acids play an important role in the production of ATP (adenosine triphosphate) from ADP (adenosine diphosphate) by phosphorylation with creatine phosphate. The more creatine phosphate available, the more ATP can be produced. Since ATP is the molecule responsible for the generation of energy, then the more ATP available the more energy is generated. Although creatine is available from many food sources, it is destroyed by cooking, and over half of what you use is made from the three amino acids, glycine, arginine and methionine. The energy produced in this way is very short-lived, and last only a few seconds - more on that later. 3. Glycine is heavily involved in the production of collagen, which is the substance that maintains the flexibility of your skin and other connective tissues while still maintaining their strength and firmness. Without glycine your skin would become slack due to the degrading effect of sunlight, free radicals and oxidation. The non essential amino acid, glycine, is believed to offer other benefits to the human body, but it is the second of those above, the production of ATP, which interests us here. ATP is an extremely important nanomolecule, second in importance to the body only to DNA, and possibly also RNA since the two are linked. RNA makes copies of your DNA structure for use in cell division and growth. When a cell expends energy for whatever reason, such as when I am typing this, or when your heart beats, or even when your liver synthesizes a protein, one of the phosphate groups is removed from the adenosine triphosphate molecule, and converts it to adenosine diphosphate (ADP). The ATP is then said to be 'spent', just as your energy is spent when you are tired and can exercise no more. The ADP is then immediately reconverted to ATP in the mitochondria, a part of every cell in your body. A cell can contain hundreds, or even thousands, of mitochondria, the number depending upon that particular cell's need for energy. Hence, cells in your muscles, or in your liver where most of the body's chemistry takes place, contain thousands of mitochondria whereas those in your scalp contain a lot less. Once changed to ATP, a phosphate is again lost when energy is expended, and so the cycle continues. Glucose is needed allow the ADP to be converted to ATP, hence the need for sugars, or the carbohydrates from which they are manufactured in your body. Each cell can contain up to a billion molecules of ATP, although the couch potatoes among you probably have a lot less! Your store of ATP molecules last about 2 to 5 seconds before being changed to ADP although more rapidly for athletes that expend a lot of energy. Then the energy stored in the form of glycogen in the liver kicks in for another 4 - 6 seconds. Additionally, you cannot expend more energy that the (eventual) sugars that you take in your diet, which can be in the form of ordinary 'sugar' (sucrose), fruit (fructose), glucose, carbohydrates that are metabolized into sugars, or any other member of the sugar family (e.g. lactose, maltose, etc.). Glycine is one of what are called glucogenic amino acids, which refers to their ability to provide glucose to the blood. Because it helps to maintain proper blood glucose levels, it is often prescribed for conditions that are caused by low glucose levels, such as hypoglycemia that shows symptoms of fatigue and tiredness, and also anemia and what is known as CFS (chronic fatigue syndrome). The one activity of the human body, in fact that of any mammal, for which ATP is essential, is the heartbeat. Without that no mammal could survive, or any other creature that relies on a circulation system for life. The only reason you heart has to beat is to pump your blood around your body, and it is your blood that contains the oxygen and nutrients needed to sustain life. Your cardiovascular health relies on lots of ATP being available to power each and every heartbeat. Analysis of the heart during the final stages of heart failure has revealed that there is a general decrease in the myocardial arginine: glycine amidinotraferase (AGAT) gene expression, which is indicative of the necessity of this enzyme for proper heart function. The enzyme is responsible for the first stage in the biosynthesis of creatine from glycine. Creatine is well known to athletes, and while it is available naturally from some food sources, it can be destroyed during cooking, and at least 50% of the creatine needed by the body is produced in the liver, pancreas and kidneys. It is creatine phosphate that is broken down into creatine and phosphate, the latter of which is used by the mitochondria to regenerate ATP from ADP.
The study carried out on the reduced AGAT levels found in heart failure patients indicates the importance of glycine to heart health. Without a good supply of glycine, there will insufficient creatine produced biochemically to generate the phosphate needed to for the ATP to produce the energy required to keep the heart pumping with the required strength. The energy provided by the mitochondria is used locally by the cells in which it is produced, and within a few seconds of that production. As explained earlier, ATP stores are used up within 2 - 5 seconds, and glycogen stores within another 4 - 6 seconds. That is why sprinters cannot keep running at maximum speed for more than around 10 seconds or so, because the immediate availability of glycine, and hence creatine, are insufficient to last longer than that. That is one reason why they have to finish those 100 meters as fast as possible, because otherwise they would run out of energy. Other than trying to win, of course! However, when it comes to the heart, ATP stores are essential, and the cells in your heart require a constant supply of ATP from creatine, which itself depends upon your intake or biosynthesis of glycine. Since dietary sources are insufficient to meet all your needs, and destroyed by cooking, a glycine supplement is the only way to ensure a sufficient intake. You cannot undernourish your heart and remain healthy.
ATP biosynthesis is essential if that of glycine theoretically is not, but the fact that 50% of your glycine requirement has to be produced by your body and the other 50% is sensitive to heat during cooking, a supplement of glycine could be essential to many people.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1912) Lutein 20mg (FloraGlo)
Date:
September 26, 2008 03:49 PM
Maintains Healthy Visual Function* It has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the first four weeks of the study, plasma levels increased five-fold from pre-supplement measures, and then remained at this level for the duration of the study. It was also shown that, due to increased deposition of lutein in optical tissues, macular pigment density increased by an average of 5.3% at the 4-week mark, and continued to increase until the duration of the study.1 A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids might play a protective role in supporting the maintenance of healthy vision.2 The Age-Related Eye Disease Study (AREDS) was a landmark study of the effects of diet and antioxidant supplementation on eye health. The study enrolled over 3500 subjects aged 55 to 80 years who were followed for approximately 6 years. Among the data collected in this multi-faceted study was a self-administered Food Frequency Questionnaire (FFQ). The AREDS Report No. 22 examined the data from the FFQs and determined that, of the nutrients evaluated, only lutein and zeaxanthin were directly related to maintaining eye health with statistical significance3. These findings corroborated similar results of an earlier multi-center study published in the Journal of the American Medical Association that also found that those with a higher intake of lutein and zeaxanthin maintained healthier eye function.4 These promising results have spurred the design of a second major clinical trial (AREDS2), which is currently enrolling participants to study the impact of supplemental xanthophylls (FloraGLO® Lutein and zeaxanthin) and other nutrients on age-related eye health.5 In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were divided into three groups and received either 10 mg FloraGLO® lutein, 10 mg FloraGLO® lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the FloraGLO® lutein and FloraGLO® lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group.6 These results demonstrate FloraGLO® lutein’s beneficial effect on maintaining healthy visual function. Newly published research has demonstrated that lutein and zeaxanthin supplementation may enhance visual performance under glare conditions. Forty healthy subjects took daily doses of 10 mg FloraGLO® Lutein plus 2 mg zeaxanthin for six months. They were evaluated for changes in macular pigment, glare disability and photostress recovery at the onset of the study, and at 1, 2, 4 and six months. After six months, subjects experienced an average increase in macular pigment optical density (MPOD) of 39% compared to baseline, and all but two participants experienced some increase in MPOD. This increase in MPOD was also directly related to measured improvements in visual performance after exposure to bright light, as well as photostress recovery.7 This study suggests another way in which lutein and zeaxanthin can help support optimal visual function in healthy individuals. Potent Antioxidant Protection* Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species.8 More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol9 demonstrating its potential as a high-powered antioxidant. A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems.10 Supports Healthy Skin* A recent randomized, double blind, placebo-controlled study has demonstrated the positive effects of oral and topical administration of lutein on skin health parameters (surface lipids, hydration, photoprotective activity, skin elasticity and skin lipid peroxidation). Forty female subjects were divided into four treatment groups. Treatment options included oral administration of 5 mg of FloraGLO® Lutein twice daily or placebo and topical administration of 50 ppm FloraGLO® Lutein twice daily or placebo. Each treatment group received either an active oral treatment with a placebo topical treatment, a placebo oral treatment with an active topical treatment, both active treatments, or both placebo treatments. Statistically significant improvements were seen in all five parameters tested in all treatment groups compared to the group receiving only placebos. The greatest overall improvements were seen in the group receiving both active oral and topical treatments, while lesser but still significant improvement was seen in both the active oral only and the active topical only groups. Additionally, oral administration of lutein conferred superior photoprotective activity (as measured by skin surface redness after exposure to ultraviolet light) and prevention of lipid peroxidation (as indicated by levels of malondialdehyde in skin lipids after exposure to ultraviolet light) than either topical lutein or placebo.11 Diverse Cinical Benefits* Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.12 Suggested Adult Use: One softgel daily with food, or as directed by a health care professional. Does Not Contain: milk, egg, wheat, sugar, sweeteners, starch, salt, or preservatives. Scientific References 1. Berendschot TT, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Opthalmol Vis Sci. 2000 Oct; 41(11): 3322-6. 2. Berendschot TT, et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Opthalmol. 2002 Dec; 120(12): 1732-7. 3. Age-Related Eye Disease Study Research Group. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol. 2007 Sep; 125(9): 1225-32. 4. Seddon JM, et al. Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration. JAMA. 1994 Nov; 272(18):1413-1420. 5. www.nei.nih.gov/neitrials/viewStudyWeb.aspx?id=120. Clinical Studies Database. Age-Related Eye Disease Study 2 (AREDS2). Last Updated 2/28/2008. Viewed 5/15/2008. 6. Richer S, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr; 75(4): 216-230. 7. Stringham JM and Hammond BR. Macular pigment and visual performance under glare conditions. Optom Vis Sci. 2008 Feb; 85(2):82-8. 8. “Lutein and Zeaxanthin”. PDR Health. www.gettingwell.com/drug_info/nmdrugprofiles/nutsupdrugs/lut_0164.shtml 9. Chitchumroonchokchai C, et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr. 2004 Dec; 134(12): 3225-32. 10. Krinsky NI. Possible biologic mechanisms for a protective role of xanthophylls. J Nutr. 2002; 132: 540S-542S. 11. Palombo P, et al. Beneficial Long-Term Effects of Combined Oral/Topical Antioxidant Treatment with the Carotenoids Lutein and Zeaxanthin on Human Skin: A Double-Blind, Placebo-Controlled Study. Skin Pharmacol Physiol. 2007; 20: 199-210. 12. Mares-Perlman JA, et al. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002; 132: 518S-524S.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1901) Ginkgo Biloba Extract
Date:
September 19, 2008 09:25 AM
Ginkgo biloba, also known as the maidenhair tree, grows naturally in two small areas of Eastern China. It is believed that even these sources are artificial, and planted and maintained by monks over many centuries, and that there are no true natural sources of the tree left. Other than these, all living ginkgo trees are now artificially farmed. The ginkgo seeds contain nuts that are a traditional food in China, served at Chinese New Year, and on other special occasions such as weddings, and is also used in traditional Chinese medicine. The seeds have been used in the treatment of coughs and asthma, and during the late 1970s and 80s, the uses of ginkgo biloba in medicine was extensively investigated with a view to determine the range of conditions that the tree could be used to treat. Given that many ancient Chinese remedies have found to be effective, and with a relevant scientific basis, this was a logical step. It has been established that ginkgo biloba could have three possible effects on the body. These are:
* Improvement in circulation including that in the small capillaries. The last of these has been responsible for many cardiovascular conditions, and disorders of the kidneys, lungs and central nervous system, and is due to the effect of the platelet-activating factor (PAF) that ginkgo appears to inhibit. Before delving deeper into the possible beneficial effects of Ginkgo, let us first examine the active ingredients believed to be involved in the perceived beneficial effects. Ginkgo leaf extract contains terpenoids (bilobalides and ginkgolides) and flavonoid glycosides. Flavones can reduce the fragility of capillaries, and protect the body from blood loss through damaged capillaries, particularly in the brain. The Ginkgolides, particularly ginkgolide B, inhibit the platelet-activating factor and so increase the fluidity of the blood that improves circulation, again particularly in the micro-capillaries of the brain. This is also why it is believed to reduce the incidence of cerebral thrombosis and resultant strokes. The antioxidant effect of ginkgo biloba extract (GBE) has been widely studied, and by scavenging free radicals the extract can help to prevent cell membrane damage, and so prevent cells from being destroyed. It has been established that pretreatment of cells with GBE can prevent such damage in rats. The anti-inflammatory properties of ginkgo biloba, as seen in some asthma patients for example, is thought to be due to the inhibition of the platelet-activating factor (PAF) by ginkgolide B, PAF playing a significant part in the inflammatory response to allergens, and PAF is now believed to be responsible for conditions such as asthma, renal diseases, central nervous system disorders and ischemia, a restriction in the blood supply, particularly to the brain. It follows, therefore, that the effect of GBE on these conditions is likely to be due to PAF inhibition, and a reduction in the inflammatory response to a number of conditions. What evidence is there for this? In fact, results of the trials carried out have been inconclusive one way or the other. Hence, a trial published by the Journal of the American Medical Association reported no effects after a 6 week trial of Ginkgo on Alzheimer’s and memory disorders. However, other trials have indicated positive effects after 6 weeks, and it could be that the GBE has to be taken for more than 6 weeks for any effects to be noticed. It is certainly believed to be a longer term treatment rather than have instant results, although some tests have shown improvement in concentration for up to 2.5 hours after treatment. The bulk of the evidence is favorable on the effect of GBE on memory disorders. Test on rats, in which the blood flow to the brain was mechanically blocked by carotid compression, indicated that ginkgo biloba promoted an increase in the glucose and ATP levels in the brain neurons. Other trials have indicated that neurological damage in mice subjected to neurotoxins was reduced by the administration of GBE, and while not conclusive with respect to humans, the effect of GBE on the brain appears to be more than just opinion. To sum up, ginkgo biloba is believed to be effective in treating the following disorders by virtue of its effect in improving the fluidity of the blood, protecting fragile capillaries from damage, exerting an antioxidant effect on free radices, and so prevent damage to cell membranes, and its inhibiting effect on platelet-activating factor: Circulation Problems Circulation problems in the arteries can lead to blood clots that in turn cause strokes and cardiac problems. By preventing blood clots through the inhibition of PAF, ginkgolide B can help to maintain a healthy circulation system that also help to maintain circulation in the very small capillaries that feed the brain. Atherosclerosis This is caused by hardening and blockage of the arteries, and one of the effects of ginkgo biloba is to soften the arteries, help to unblock them and to prevent plaque formation by its antioxidant effect on the free radicals that cause the plaque by oxidation of LDL lipids. This is particularly true of the cerebral arteries. Memory Impairment The increased blood flow to the brain that GBE promotes can help to improve memory, although test are indicating that treatment has to continue for 6 weeks or more for it to be effective. Reduced blood flow to the brain is a common cause of memory impairment. Alzheimer’s disease Ginkgo biloba has been used in the treatment of the symptoms of this condition, although it cannot be cured. It is thought that the improved circulation in the brain makes best use of the unaffected brain cells, improving memory and cognitive thought. Reynard’s Disease This is a condition where the extremities fail to warm up after being exposed to cold, and is caused by poor circulation in the small capillaries in which the blood pressure is very low. They symptoms are numbness and pins and needles, and GBE helps to overcome this condition due to improvement in the circulation and protection of the capillaries by rendering them less fragile. Vertigo GBE can help to reduce the symptoms of vertigo such as nausea and dizziness. This is believed, once again, to be due to an improvement in blood circulation.
There are few doubts that ginkgo biloba extract improves the circulation, particularly in the micro-capillaries in the brain and extremities of the body, and also possesses antioxidant properties, both of which help to maintain and improve the memory, and that combined with its effect on the platelet-activating factor, most of the properties of GBE is due to its capacity to maintain and improve circulation, particularly through those blood vessels closest to the blood-brain barrier.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1894) Essential Fatty Acids (omega-3) ( Primrose Oil)
Date:
September 11, 2008 09:04 AM
A deficiency in essential fatty acids can be linked to many ailments. When the body lacks linoleic acid in the diet, adverse symptoms result. Such symptoms include: acne, changes in personality or behavior, gallbladder dysfunction, slow healing wounds, cardiovascular problems, prostate inflammation, thirst due to excessive perspiration, arthritis, miscarriage, poor growth, kidney problems, muscle tremors, skin disorders, and sterility in males. Low contents or a lack of linolenic acid in the diet can also cause many adverse symptoms. These symptoms include poor growth, learning disability, tingling in the extremities, impaired motor coordination, and poor vision. When adequate amounts of dietary fatty acids are obtained in the deficient person, adverse symptoms will disappear. Unfortunately, long-term deficiencies of essential fatty acids can eventually lead to death. Because the human body requires forty-five known essential nutrients and requires linoleic acid more than any other, researchers estimate that the body needs at least three to six grams a day of linoleic acid in order to prevent deficiency symptoms. This is equivalent to one to two percent of your daily caloric intake. However, a much larger amount can be helpful to encourage and preserve optimum health. Although the requirements are different for each person, factors such as stress, diet, and amount of physical activity that is engaged in daily must be taken into account. For example, an obese person who eats a lot of saturated fats will need a lot more essential fatty acids than a thin person who is cautious about the amount of saturated fats that are included in their diet. Saturated fats interfere with the absorption and metabolism of linoleic acid. A well-balanced diet will include primary nutrients such as vitamins B3, B6, C, zinc, and vitamin A. This will help the body to utilize essential fatty acids much more efficiently. It should be mentioned that the ability of lipids to hold high levels of oxygen has negative effects for those who are obese. By having increased oxygen in fat reserves, one can experience lipid oxidation, which leads to free radical formation, which in turn increases many tissue pathologies. In order to avoid this process, a diet or supplementation that is rich in antioxidant nutrients such as vitamins A, C, and E is encouraged. Many factors can get in the way of fatty acid metabolism. These include a diet that is high in saturated fats and cholesterol, aging, alcohol, high blood sugar, viral infections, and aspirin use. It is recommended that people stay away from fats that have been altered from their normal, health-giving state to the point in which they actually cause damage to the cells of the body. In an ideal state, a person who is health conscious will avoid any foods that are deep-fried, as they are especially dangerous to the human body. However, because we are all humans, it is almost impossible to eat a perfect diet in this day and age.
Therefore, taking an essential fatty acid supplement is a great idea that is recommended by many health experts to offset the damage that is often done to your body by consuming the unwanted, yet inevitable, bad fats. Essential fatty acids can regulate hormone production in the body and stabilize ones emotional state if it is due to a hormone imbalance. Have you had your essential fatty acids today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1888) |