Date: July 01, 2008 05:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Rescue From High Cholesterol

Cholesterol is an unsaturated waxy solid that is manufactured in the body and has important functions relative to cell membrane management. It is also known to help produce bile to digest fats and can help in metabolizing fat-soluble vitamins. Cholesterol is both made in tissue membranes and derived through the diet. This is where the basis of good and bad cholesterol comes into play. Cholesterol that is made in tissue membranes is transported by high-density lipoprotein (HDL), which delivers the cholesterol to the liver. HDL is thought to remove cholesterol from arteries and delivers it back to the liver for processing. Increased levels of HDL have also been deemed as protective against heart disease. Low-density lipoprotein (LDL), on the other hand, is dietary cholesterol that is transported and carries cholesterol from the liver to tissue membranes.

This factor is not what makes LDL cholesterol bad, instead it is the amount of cholesterol in the wrong place at the wrong time. Large amounts of cholesterol and LDL in the arteries can lead to plaques that gradually damage arteries over time, which leads to heart attack, stroke, or some other type of heart and vascular diseases. Because of these reasons, cholesterol management for heart and vascular health focuses on lowering LDL cholesterol. What is often overlooked is the value of Raising HDL cholesterol levels, which can improve removal of cholesterol from dangerous locations in the arteries.

The diet greatly influences health, and by addressing macro and micro nutrients, cholesterol health can be greatly reduced. Macro nutrients that affect cholesterol include fiber, protein, and fats. Micro nutrients are things such as vitamins and minerals, especially those that have potent antioxidant mechanisms, which can affect lipid peroxidation. Fiber, which has long been recommended by the American Heart association (AHA), lowers total and LDL cholesterol levels, while Raising HDL levels. Although fiber is straightforward, the trick with protein is to always find a good source that does not have saturated fat and cholesterol that can negate its benefits. Although whey protein is animal-based, it has been shown to lower LDL cholesterol. However, many people have looked to soy to provide cholesterol-managing protein.

When it comes to natural products, there are a few key nutrients that can help with cholesterol management. Among these are DHA, EPA, Omega-3s and 6s, Vitamin E, Vitamin B, and Niacin. Limiting oxidative stress and lipid peroxidation are also important components of cholesterol management. Although micro nutrients give a good level of protection from oxidation, a large amount of antioxidant fighters comes from botanicals, flavonoids, and carotenoids. Some flavonoids that can help with cholesterol care include cocoa, tea, and fruit.

Citrus bioflavonoids also help with antioxidant management, especially when they are combined with vitamin E. Fruits such as pomegranate and grape seed extract help to limit LDL oxidation. Botanicals such as garlic, which contain antioxidant constituents help to lower total and LDL cholesterol while still maintaining HDL levels. Other suggestions to help maintain healthy cholesterol levels include pine bark extract as well as some types of algae.

Whether you’re attempting to use just one or many of these approaches to battle cholesterol levels, there are many well-researched ways to both lower the bad and raise the good cholesterol.

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Date: November 10, 2007 11:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Are Inflammation, Immunity, And Allergic Reactions A Role For Supplements?

Inflammation, immunity diseases and allergic reactions are all connected with your immune system, and the way the body reacts to what it considers to be foreign invaders that are a risk to your health. Although you may not understand that all three have the basic underlying cause, in fact they do, and here is why.

Inflammation manifests as pain and swelling in the inflamed area, and not only can the area also get hot, but it can also raise your temperature in general, commonly called a fever. Fever is the body’s way of Raising temperature above that at which foreign organisms such as bacteria and viruses can live, so any inflammatory condition that results in fever by definition must be an immune response through the body trying to eliminate foreign invaders.

If your body gets injured in any way, your immune system responds, and usually calms down again if decides that the injury is not serious. Your immune system is actually initiated by what are known as pro-inflammatory hormones, such as prostaglandins that stimulate the nerves to signal pain and swell the blood vessels close to the injury to make room for the large white blood cells when they arrive. That also allows blood and plasma to rush out and cause swelling at the site of the injury. Other prostaglandins act to quell the immune response, and get your body back to normal.

Another such hormone is a cytokine, which informs the brain of the intrusion. Some cytokines called leukocytes stop the immune system when necessary to prevent the destruction of healthy tissue, and also halt the inflammatory response. If the leukocytes are not working properly, the body can be severely damaged as the immune system becomes uncontrolled and starts to attack healthy tissue.

Then there are the histamines that allow you to expel the agents causing the problem by sneezing, watery eyes, runny noses and scratching. They lead lymphatic fluid and blood to the site of the problem in order that the invasion can be attacked and destroyed.

It is the histamines that provide what is commonly referred to as an allergic reaction, which is really the immune system coming into action to remove invaders such as pollen, dust mites and any other agent that can cause an allergy. Immunity is caused by introducing small amounts of the agent into the blood, so that the immune system can develop a memory of them. Then, when the same invader returns at a later date, the system can immediately attack them with the antibodies that have been produced.

All of these: inflammation, immunity and allergies, are caused by the reaction of the immune system to what it perceives as an invader. Normally these are bacteria and viruses, but sometimes they react to other foreign bodies such as pollen. In some people this provokes no response at all, while in others it provokes the immune system to create antibodies against the pollen, and emit histamine to expel it.

Substances that cause allergies are referred to as allergens. Many allergens are environmental, such as dust, pollen and peanuts. Some people are allergic to certain animals, such as cats or dogs, and others to chemicals in the air such as hydrocarbon emissions, particularly when in particulate form.

The symptoms can be simple, such as a runny nose, a cough and hay fever or more complex such as hives, eczema and asthma. All of these are caused by the immune system reacting to an invader. There are also foods that cause internal inflammation, such as shellfish and whitefish, eggs and tomatoes. Many of these can be extreme, leading to serious illness and can even be fatal. So what can be done to treat people who are particularly prone to inflammation and allergic reactions?

Omega-3 fatty acids have been found to reduce inflammation, unlike their Omega-6 cousins that appear to increase it. Omega-3 oils contain chemicals known as eicosanoids, of which the prostaglandins are an example. While this might seem paradoxical, since prostaglandins are what set off the whole process, there are many types of these. Prostaglandin E2 is the type that leads to allergic immune reactions, and omega-3 fatty acids reduce the concentration of these in the blood.

Those who eat little fish tend to suffer more from inflammatory conditions such as arthritis and other conditions indicating a lack of control of the immune system. On the other hand, processed foods contain more omega-6 fatty acids that can promote these conditions. The major components of omega-3 oils are alpha-linolenic acid (ALA) and eicosapentaenoic acid (EPA) and also DHA, docosahexaenoic acid. These are all anti-inflammatories and have been shown to have very positive effects on inflammatory conditions such as rheumatoid arthritis, Crohn’s disease and eczema. Each of these is a different type of inflammatory condition caused by inappropriate immune response.

However, it not just fish oils that can help resolve problems with our immune system. Quercetin is what is known as a flavonoid. It is a strong anti-oxidant and natural anti-histamine that combats histamine release and the swelling associated with the immune response to allergens. It also counters the inflammatory agents of arthritis and so helps to reduce the pain associated with many of these conditions. It appears to work better in conjunction with bromelain, a very powerful anti-inflammatory that also possesses anti-allergen response properties. Bromelain is extracted from pineapple stems.

Another natural product is a resin extract that is obtained from the Boswellia serrata tree. It has powerful anti-inflammatory properties, and has been recommended for the treatment of arthritis (rheumatoid and osteo), Crohn’s disease and has been suggested as a treatment for asthma, though studies are still under way. However, world wide experience is that Boswellia is effective against gout, psoriasis and ulcerative colitis, to name another three totally different inflammatory conditions.

What all of this indicates are two things. First that inflammation, immunity and allergic reactions are connected conditions, and due to either poor control over or an over stimulated immune response to what the body perceives as being abnormal, in the way that hormones and other chemicals that are used to control our immunity detect it to be.

Secondly, there are many natural products that can be used as supplements to treat these effects caused by the immune system, and that their effectiveness has been proven, if not by scientific study, then by generations of traditional application as treatments of the symptoms of the conditions concerned.

However, although many have been proved by scientific study, others have not, and you should always refer to your physician before undergoing any treatment other than that prescribed. Also, there is incontrovertible evidence that the role for supplements in the treatment of inflammation, immunity and allergic reactions are beneficial. Many use nothing else.

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Date: October 06, 2006 09:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lower Cholesterol Naturally!

Because of organizations like the American Heart Association (AHA), we’ve learned a lot about cholesterol and how it affects our health. Thanks to these educational organizations, we know that high cholesterol levels can increase our risk for heart attacks and strokes and, by lowering these levels, we reduce these risks as well as keep our hearts and blood vessels healthy. We also know that our cholesterol levels can be improved through exercise, diet, and weight loss.

Although we’ve learned a lot through these educational organizations, there are still a few misconceptions about cholesterol. One of these being that not all cholesterol is harmful. There are both “good” and “bad” forms of cholesterol and a good balance between the two is what is needed for a healthy heart. Because so much emphasis is placed on lowering “bad” cholesterol levels, not enough attention is paid to the benefit of Raising “good” cholesterol levels (HDL). Research states that Raising HDL levels can provide even greater protection against cardiovascular disease than just simply lowering “bad” cholesterol levels. By Raising HDL levels by simply 1%, the risk of heart disease can be lowered by 2% in men and 3% in women. Many studies have shown that low HDL cholesterol levels are an independent risk factor in heart disease. This is extremely important because we’ve learned that despite efforts to change a person’s diet and exercise habits, some people’s cholesterol levels are still unhealthy.

Prescription drugs to lower cholesterol are now available and have been proven by multiple studies to be very successful. The statins’ effectiveness in reducing LDL (“bad”) cholesterol has produced highly significant reductions in heart attacks and strokes. Although these medications do lower cholesterol levels, their side effects must be considered. Statin drugs can cause liver irritation, reduce CoQ10 levels in the body, are associated with myopathy, and are even linked to a rare and sometimes fatal condition called rhabdomyolysis. These drugs also have a relatively small effect on good (HDL) cholesterol levels. Thankfully, there are safe and effective solutions available that can help you manage your cholesterol levels naturally. However, first we must review what we know about cholesterol and heart disease.

Cholesterol is a fat-like substance needed to help digest fats, strengthen cell membranes, make hormones and insulate nerves. Although it is found in every cell of the body, cholesterol is mainly made in the liver, as well as cells lining the small intestine. Even though our bodies make all the cholesterol we need, we also get cholesterol from the foods we eat, such as egg yolks and organ meats. All foods from animal sources contain cholesterol, while plant derived food, including peanut butter and avocado, contains no cholesterol at all.

Cholesterol is important to many functions of the body. However, too much cholesterol in the bloodstream is extremely dangerous. After blood cholesterol reaches high levels, it builds up on the artery walls, and thus increasing the risk for blood clots, heart attack, and stroke. If the cholesterol clogs any of the coronary arteries, the heart’s supply of oxygen and nutrients will diminish, resulting in coronary heart disease, angina, or even heart attack.

Because cholesterol and other fats can’t dissolve in the blood and thereby can’t travel on their own, they have to be transported to and from the cells by lipoproteins. The two major lipoproteins are low density lipoproteins (LDL or “bad cholesterol) and high density lipoproteins (HDL or “good cholesterol”) LDLs carry cholesterol throughout the body to the cells and cause artherosclerosis by clogging up our arteries with fat. On the other hand, HDL prevents the fat buildup by carrying it away from the arteries and to the liver where it can be eliminated. Although high levels of LDL are associated with cardiovascular disease, high HDL can drastically reduce your risk of heart disease. As a result, the AHA has established three guidelines to keep your heart healthy: HDL levels about 40 for men and above 50 for women, LDL levels between 100 and 159, and a total cholesterol (HDL and LDL) of under 200.

Triglycerides are fats used as fuel by the body and a source for metabolism. These levels can fluctuate easily but increased levels are almost always a sign of too much carbohydrate and sugar intake. High amounts of triglycerides make the blood less capable of transporting oxygen and are another factor for cardiovascular disease. Thankfully, the HDL and LDL blend mentioned earlier can safely and effectively lower triglyceride levels.

It has been shown that high levels of HDL cholesterol are inversely related to coronary artery disease risk. However, what people do not know is that there are different subtypes of HDl, including HDL-2 and HDL-3. HDL-3 is produced by the liver and intestines and is responsible for scooping up free cholesterol from the blood vessel walls. The cholesterol carried by HDL-3 is chemically modified, forming a larger-sized subtype, known as HDL-2, or “mature HDL.” HDL-2 transports cholesterol to the liver for processing and elimination, and its molecules are then recirculated in the blood stream. Research has shown that HDL-2 provides more heart-protection because it moves the cholesterol away from arterial walls, and holds a greater number of receptor sites which allows it to carry a larger amount of cholesterol to the liver.

Although many prescription medications have been developed to lower bad cholesterol, there are very few medications that target good cholesterol. Therefore, patients with naturally low HDL cholesterol, who can not alter these levels through diet and exercise, have limited medical options to reduce their risk of heart disease. Multiple nutrients have been clinically shown to favorably alter good cholesterol levels including: vitamins C, E, B6, B12, niacin, folic acid, magnesium and selenium, with protein-building amino acids, powerful antioxidants such as coenzyme Q10, alpha lipoic acid, N-acetyle cysteine, and policosanol, and extracts of hawthorn, garlic, grape seed, and soy isoflavones. Although this HDL-boosting combination does not result in a significant reduction in LDL, antioxidants found in this formulation can help stabilize LDL and prevent build up in the arterial wall.

This formula combines essential vitamins and minerals, at levels recommended by the American Heart Association. It contains amino acids, antioxidants, and botanicals that have all been used safely for years. No serious adverse effects have been found following supplementation and the combination is safe to use with statin drugs.

Plant sterols, found in nuts, vegetable oils, corn, and rice are structurally similar to cholesterol and are able to block its absorption. Each day the liver receives about 800 mg of cholesterol from intestinal absorption through receptor sites. After entering these channels, the cholesterol is absorbed into the bloodstream. Since plant sterols look similar to cholesterol, they fit perfectly into these receptor sites and block the absorption, which allows the cholesterol to remain in our intestines where it can eventually be excreted. A large amount of plant sterols reduces the amount of cholesterol transported from the intestinal tract to the liver. This cholesterol reduction causes a decrease in LDL levels.

Even if a person does not have high cholesterol levels, reducing bad and Raising good cholesterol greatly reduces their risk for ever developing chronic heart disease. Due to side effects, physicians do not normally prescribe statin drugs to people without actual heart disease of high LDL cholesterol levels. Instead, they recommend dietary changes. The HDL-boosting combination and LDL-lowering pantethine and plant sterols blend can effectively help people with heart disease, uncontrolled cholesterol levels, high triglyceride levels, or people who just want to improve their heart health.

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Date: June 07, 2006 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Syndrom Healing and 5-HTP

Boomer Breakthrough – Keeping in the Game

If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves.

Mood, Anxiety and Depression

Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use.

How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels.

Serotonin the Antiaging Neurotransmitter

Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients.

Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period.

5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin.

It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia.

Pain, Per-menopause and PMS

5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at Raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants.

Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability.

Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller.

Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety.

Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain.

Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.

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Date: May 05, 2006 06:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Best Sugar Balance Svetol (green coffee extract)

Ingredients

Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids.

In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.*

Benefits

Maintains healthy blood sugar levels when used as a part of the diet*

CHLOROGENIC ACIDS

Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1

Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3

Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.

Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.

Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT).

More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year.

The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5

It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism.

A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on Raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6

RESEARCH ON SVETOL®

Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results.

In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7

Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption.

The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.*

SAFETY

Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7

*This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4.

2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402.

3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7.

4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10.

5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15.

6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.

7) Berkem.Text on Svetol®.Gardonne, France: November 2005.

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Date: December 07, 2005 10:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Green Tea Extract Fact Sheet

LIKELY USERS: People wanting antioxidant protection; Those trying to control cholesterol; People with high levels of inflammatory iron, including eaters of red meat; Those seeking to avoid caffeine, but wanting the benefits of green tea.

KEY INGREDIENT(S): Green tea extract (Camellia sinensis) 400 mg

MAIN PRODUCT FEATURES:

Total EGCg content: 50% (200 mg.) (Epigallocatechin gallate, a Catechin) Total Catechins content: 80% (by HPLC method) (Catechins are a form of Polyphenol) Total Polyphenols content: 98% (by UV method) Polyphenols, especially catechins (including EGCg), are the main active ingredients in green tea, which act as antioxidants and bind iron, which may prevent some iron-dependent inflammation.

Less than 1% caffeine content, naturally occurring (versus one cup of green tea’s roughly 40 mg. of caffeine). There should be only around 3 mg. of caffeine, per capsule.

OTHER IMPORTANT ISSUES:

• Highest dose in one capsule.
• Vegetarian form.
• One capsule contains as much EGCg as about three cups of green tea.
• Green tea may correct cholesterol imbalances by Raising HDL and lowering LDL cholesterol, while preventing LDL from oxidizing. Oxidized cholesterol is a key risk factor for cardiovascular disease.
• Green tea may also be a mild anticoagulant, or “blood-thinner”.
• Green tea has been shown to help maintain levels of desirable intestinal bacteria.

  AMOUNT TO USE: One or more Vcaps® a day, preferably with meals. Three to four capsules would provide about the same antioxidant benefits as ten cups of tea, an amount used successfully in some studies.

  COMPLEMENTARY PRODUCTS: Other antioxidants including Vitamins A, C and E, selenium, alpha lipoic acid, NAC, grape seed and skin extracts, pycnogenol and pine extracts, pomegranate and various berries.

  CAUTIONS:Due to the lack of any substantial amount of caffeine in this formula, most of the usual tea cautions are not applicable. While the mild anticoagulant effects will not normally affect most people to any great degree, some caution should be used if taking blood-thinning drugs. Green tea may help the effects of chemotherapy drugs while preventing the normal tissue damage from these drugs. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

  
  
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  Vitanet ®
  
  

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  The Refreshing Feeling of All Things New
  

  Date: December 05, 2005 07:07 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: The Refreshing Feeling of All Things New
  

  The Refreshing Feeling of All Things New.

  Springtime! We realize it's time to open the windows and let the fresh air in once again after a season of having everything shut up tight. More time spent indoors through the winter can mean months of recireculated air, less time spent outside, and overindulgence in holiday food. That's a recipe for toxic build-up. As you start to think about spring cleaning you will do inside your house, don't forget about the cleansing that is good for the mind and body. Decker Weiss, NMD To cleanse and detoxify the whole body, rely on Enzymatic Therapy's Whole Body Cleanse†. The National Cancer Institute recommends eating 20 to 35 grams of fiber a day, yet most Americans get only 15 grams. It's clear the right amount and the right type of fiber can make a real difference in cleansing our system and maintaining regularity day by day.† Taking Whole Body Cleanse for thorough periodic detoxification and Fiber Fusion to tone and renew your system on a daily basis is a great way to greet Spring.†

  A Time for Rejuvenation.

  Every day we are exposed to toxins in our food, water, and the air we breathe. The natural variation in volume and variety of today's environmental contaminants is a challenge for your body's built-in detoxification systems. Toxins Come from Many Sources: Foods that may have been exposed to pesticides, herbicides and fertilizers.

  Hormones used in Raising livestock.

  The burning of fossil fuels in automobiles and utility power plants which can affect air quality.

  Treated wastewater that flows into rivers, lakes and streams which can contain unwanted pollutants.

  Whole Body Cleanse† and Simple Cleanse † from Enzymatic Therapy handle the environmental toxins you take in from the environment (like pollutants) as well as toxins that you make yourself (like free radicals), without depleting your body's store of beneficial nutrients.† Which on is right for me?
  
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  Vitanet ®
  
  

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  Mother’s Little Breakfast Cup board Helpers
  

  Date: October 21, 2005 10:36 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Mother’s Little Breakfast Cup board Helpers
  

  Mother’s Breakfast Helpers

  It’s oft-said but still true-breakfast really is the most important meal of the day, especially when you’re expecting. To make morning eating easier while trying to do eight things at once, Jones and Hudson recommend keeping your kitchen well supplied with whole-grain versions of cereal, bread, English muffins and cereal bars (along with that old healthy-breakfast standby, oatmeal). And stocking up on yogurt, fresh fruit and soy-or whey based protein powder lets you whip up breakfast smoothies in a jif.

  While you’re at it, have plenty of good-stuff snacks on hand, including Raisins and other dried fruits, nuts and nut butters, fruit sauces, oatmeal cookies, whole-grain pita bread with hummus, low-fat cottage cheese and hard-boiled eggs.

  Minor miseries like heartburn and constipation can set in as your uterus starts elbowing other internal organs out of the way. You can head off heartburn by eating several small meals throughout the day and by taking the time to eat more slowly. Don’t lie down right after eating and when you do go to bed, keep your head elevated. The fiber in all those whole grains and produce should help keep things moving along smartly in your intestines, especially if you remember to stay well hydrated; if it isn’t enough, try adding some supplemental fiber to your daily routine.

  Another way to ease constipation is to get adequate exercise. At one time, “it was believe that an active pregnant woman would divert blood away from her growing fetus and toward her exercising muscles, resulting in a smaller baby,” say Karen Nordahl, Carl Petersen and Renee Jeffrey’s, authors of Fit to Deliver (Hartley & Marks). Ain’t so; exercise actually helps reduce the risk of pregnancy-induced diabetes and high blood pressure while giving you more energy and helping you rebound to your pre-pregnancy weigh after delivery (just check with your health practitioner first). They recommend a program that emphasizes aerobics and exercises designed to improve your balance and strengthen your body’s core muscles’, the ones that stabilize and support your back and abdomen.

  Exercise is just one component of an overall healthy lifestyle. That includes the negative stuff-you know, not smoking or drinking- and the positive stuff, like yoga and breathwork to help you feel integrated and whole. If you’re new to yoga, try taking a class with a qualified instructor, preferably someone with experience in teaching pregnant women.

  One last thing: Enjoy this special time in your life as you await the great adventure known as motherhood.

  
  
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  Vitanet ®
  
  

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  Boron for prostate support
  

  Date: October 05, 2005 09:18 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Boron for prostate support
  

  Boron for Prostate Support

  Boron – According to the study done last year at UCLA, men with highest boron intake were 65 percent less likely to develop prostate cancer than men with the lower boron intake. The researchers compared dietary patterns of 76 men with prostate cancer to that of 7,651 males with out cancer. Men in the lowest quartile of boron consumption ate about one slice of fruit per day, while those in the highest quartile ate 3.5 servings of fruit per day. The researchers found that boron’s cancer fighting effects seem to be specific for prostate cancer. Foods that are high in boron include: red wine, Raisins, peanuts, apples, pears, peaches, oranges, grapes, lima beans, and peanut butter.

  
  
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  Vitanet ®
  
  

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  Depressed? Try these “super 5” supplements
  

  Date: August 09, 2005 03:25 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Depressed? Try these “super 5” supplements
  

  Depressed? Try these “super 5” supplements

  While we must first address basic health issues and tackle them individually, nature has provided us with a number of compounds capable of treatment depression by safely Raising serotonin levels and by boosting oxygen supplies to brain cells.

  1. 5-HTP, a metabolite of the amino acid tryptophan, has the ability to boost serotonin production without the negative side effects of drugs like Prozac. It has been successfully used in clinical trials with people suffering from depression that were resistant to traditional therapies. Because it can boost serotonin without the negative side effects of antidepressant drugs, it is one of nature’s best choices as a natural remedy for depression, anxiety and sleep disorders.

  2. St. John’s worth as received considerable attention for its ability to successfully treat mild to moderate depression. Numerous studies have concluded that many patients respond as well or better to St. John’s wort than standard drugs. Not surprisingly, German doctors prescribe St. John’s wort four times as often as Prozac for depression.

  3. Ginkgo has enjoyed tremendous popularity as an herb capable of boosting memory function. Because depression is viewed by some experts as a condition of brain under-stimulation, ginkgo may be valuable in that it can boost brain cell oxygenation by enhancing blood flow. A French study found that 166 patients with mental disorders significantly improved with ginkgo therapy.

  4. Phenylalanine and Tyr osine are two amino acids which elevate serotonin levels and curb excess carbohydrate cravings. Dr. Oscar Janifer, M.D. in his book A Different Kind of Healing, comments: “I’ve had great results with tyrosine. It’s like a natural antidepressant and is a precursor to the neurotransmitter norepinephrine.” Phenylalanine acts as precursor to the amines that comprise neurotransmitters (serotonin) in the brain.

  5 . NADH, a form of niacin, plays a vital role in the energy production of all cells and is thought to boost brain cell metabolism. It is currently used for Alzheimer’s disease and seems well suited to older individuals suffering fro m depression. NADH levels significantly decline with age.

  Virtually any physical stressor can disrupt delicate chemical balances in the brain causing us to feel unexplainably sad for prolonged periods of time. Take a moment to evaluate your life, and look into natural means for assistance.

  
  
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  Vitanet ®
  
  

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  Lowering cholesterol safely
  

  Date: July 27, 2005 04:10 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Lowering cholesterol safely
  

  Lowering cholesterol safely.

  By Kim Vanderlinden, N.D., D.T.C.M.

  Atherosclerosis and its complications are major causes of death in the United States and have reached epidemic proportions throughout all of the Western world. Heart disease accounts for 36% of all deaths among Americans and ranks as the number-one killer; stroke; another complication of atherosclerosis; is the third most common cause of death.

  Foremost in the prevention and treatment of heart disease is the reduction of blood cholesterol levels. The evidence overwhelmingly demonstrates that elevated cholesterol levels greatly increase the risk of death due to heart disease. The first step in reducing risk for heart disease is keeping your total blood cholesterol level below 200 mg/dl (milligrams per deciliter).

  Not all cholesterol is bad; it serves many functions in the body, including the manufacture of sex hormones and bile acids. Without cholesterol, many body processed would not function properly.

  Cholesterol is transported in the blood by molecules known as lipoproteins. Cholesterol bound to low density lipoprotein, or LDL, is often referred to as the “bad” cholesterol, while cholesterol bound to high-density lipoprotein, or HDL, is referred to as the “good” cholesterol. LDL cholesterol increases the risk of heart disease, strokes, and high blood pressure, while HDL cholesterol actually protects against heart disease.

  LDL transports cholesterol to the tissues. HDL, on the other hand, transports cholesterol to the liver for metabolism and excretion from the body. Therefore, the HDL-to-LDL ratio largely determines whether cholesterol is being deposited into tissues or broken down and excreted. The risk for heart disease can be reduced dramatically by lowering LDL cholesterol while simultaneously Raising HDL cholesterol levels. Research has shown that for every one percent increase in HDL levels, the risk for a heart attack drops three to four percent.

  Dietary cholesterol

  Dietary cholesterol is a major risk factor in developing atherosclerosis. The evidence is substantial. However, several studies have shown that a lower dietary cholesterol intake was associated with up to a 37% lower risk of death from any cause, or an increased life expectancy of roughly 3.4 years.

  Although dietary cholesterol intake is an important contributor to atherosclerosis, most of the cholesterol in the body is actually manufactured in the liver. Reducing dietary cholesterol alone is not always sufficient to lower blood cholesterol levels.

  Common drugs

  In an attempt to reduce blood cholesterol levels, many physicians are ignoring the need to give dietary recommendations and are instead utilizing drugs as the primary treatment. Using drugs before diet is clearly not the best approach, in terms of both effectiveness and cost. In fact, the Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Cholesterol in Adults clearly states: “Dietary therapy is the primary cholesterol-lowering treatment.”

  The drugs lovastatin (Mevacor), prevastin (Pravachol), and simvastatin (Zocor) are commonly used to lower blood cholesterol levels. The main side effect of these drugs is liver damage. In fact, due to the seriousness of the possible adverse effects on the liver, it is necessary to have periodic blood tests to determine if the drug is harming the liver. Other side effects include: muscle breakdown, muscle pain, nausea, diarrhea, flatus, abdominal pain, headache, and skin rash.

  Lowering cholesterol

  The most important first approach to lowering a high cholesterol level is to follow a healthful diet and lifestyle. The dietary changes are simple: Eat less saturated fat and cholesterol by reducing or eliminating the amounts of animal products in the diet; increase consumption of fiber-rich plant foods (fruits, grains, and legumes); and lose weight, if necessary. Lifestyle changes include; Regular aerobic exercise; stop smoking; and reduce or eliminate consumption of coffee (both caffeinated and decaffeinated).

  Here are the six key recommendations of U.S. Surgeon General, American Heart Association, and the National Research Council’s Committee on Diet and Health:

  
  1. Reduce total fat intake to 30% or less of calories; reduce saturated fat intake to less than 10% of calories; reduce the intake of cholesterol to less than 300 mg daily.
  2. Eat five or more servings daily of a combination of vegetables and fruits, especially green and yellow vegetables and citrus fruits.
  3. Increase the intake of fiber and complex carbohydrates by eating sic or more servings daily of a combination of breads, cereals, and legumes.
  4. Maintain protein intake at moderate levels
  5. Balance food intake and physical activity to maintain appropriate body weight.
  6. Limit the intake of alcohol, refined carbohydrates (sugar), and salt.

  Natural alternatives

  When there is a need for additional support to the dietary and lifestyle practices that can lower cholesterol levels, it simply makes more sense to use safer and more effective natural alternatives. When evaluating overall effectiveness, both LDL and HDL cholesterol levels must be taken into consideration. When you look at the cost, safety, and effectiveness, it is clear that natural alternatives are substantially superior to standard drug therapy.

  Keep in mind that the natural alternatives discussed are, just like the dugs, still best utilized in a comprehensive program that stresses a healthful diet and lifestyle.

  Niacin

  Niacin, or vitamin B3, has long been used to lower cholesterol levels. In fact, niacin is recommended by the National CholesterolEducation Program as the first “drug” to use to lower blood cholesterol levels.

  The safest form of niacin at present is known as inositol hexaniacinate. This form of niacin has long been used in Europe to lower cholesterol levels and also to improve blood flow. It yields slightly better results than standard niacin, but is much better tolerated, both in terms of flushing and, more importantm long term side effects.

  Gugulipid

  Gugulipid is the standardized extract of the mukul myrrh tree that is native to India. Several clinical studies have confirmed that gugulipid has an ability to lower both cholesterol and triglyceride levels. Typically, cholesterol levels will drop 14% to 27% in a four- to twelve-week period, while triglyceride levels will drop from 22% to 30%.

  The dosage of gugulipid is based on its guggulsterone content. Clinical studies have demonstrated that gugulipid extracts standardized to contain 25 mg of guggulsterone per tablet given three times per day is an effective treatment for elevated cholesterol levels, elevated triglyceride levels, or both.

  Garlic and onions

  Garlic and onions exert numerous beneficial effects on the cardiovascular system, including lowering blood lipids and blood pressure. Numerous studies have demonstrated that both garlic and onions are effective in lowering LDL-cholesterol and triglycerides while simultaneously Raising HDL-cholesterol levels.

  Final Comments

  Without question, the best approach to lowering cholesterol levels is through diet and lifestyle modifications. When additional support is require, there are safer and more effective natural alternatives to commonly prescribed drugs.

  The goal of therapy, whether natural or synthetic, is to get blood lipid levels down into target ranges as quickly as possible. Once the target range has been achieved, begin reducing the amount of medicine by half, or take it every other day. Recheck your cholesterol levels in one month. If they have stabilized or continued to improve, you may no longer need the medication. If the levels begin to rise again, return to previous dosage.

  If you are currently on a cholesterol-lowering drug, you must consult your doctor before discontinuing the medication.

  
  
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  Vitanet ®
  
  

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  Quercetin and Bromelain - for better health.
  

  Date: July 04, 2005 10:28 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Quercetin and Bromelain - for better health.
  

• Maintains Tissue Comfort by Regulating Enzymes*
• Helps Maintain Normal Blood Viscosity*
• Bromelain May Enhance Quercetin Absorption

Benefits

Down-regulates the Body’s Response to Environmental Challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10

Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges.

Maintains Tissue Comfort by Regulating Enzymes*

Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures.

Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13

Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16

Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of free-radicals such as hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19

Helps Maintain Normal Blood Viscosity*

Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by Raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.*

Bromelain May Enhance Quercetin Absorption

In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.

• *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1. Nishino, H., et. al., “Quercetin interacts with calmodulin, a calcium regulatory protein.” Experientia 1984;40:184-5.
2. Busse, W.W., Kopp, D.E., Middleton, E., “Flavonoid modulation of human neutrophil function.” J. Allergy Clin. Immunol. 1984;73:801-9.
3. Havsteen, B,. “Flavonoids, a class of natural products of high pharmacological potency.” Biochemical Pharmacology 1983;32(7):1141-48.
4. Middleton, E., “The Flavonoids.” Trends in Pharmaceutical Sciences 1984;5:335-8.
5. Otsuka, H. et. al., “Histochemical and functional characteristics of metachromatic cells in the nasal epithelium in allergic rhinitis: Studies of nasal scrapings and their dispersed cells.” J. Allergy Clin. Immunol.1995;96:528-36.
6. Fox, C.C., et. al., “Comparison of human lung and intestinal mast cells.” J. Allergy and Clin. Immunol. 1988;81:89-94.
7. Pearce, F.L., Befus, A.D., Bienenstock, J., “Mucosal mast cells III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.” J. Allergy and Clin. Immunol. 1984;73:819-23.
8. Middleton, E. Drzewiecki, G., Krishnarao, D., “Quercetin: an inhibitor of antigen-induced human basophil histamine release.” J. of Immunology 1981;127(2):546-50.
9. Bennett, J.P., Gomperts, B.D., Wollenweber, E.,“ Inhibitory effects of natural flavonoids on secretion from mast cell and neutrophils.” Arzneim. Forsch/Drug Res. 1981;31(3):433-7.
10. Middleton, E. Drzewiecki G., “Naturally occurring flavonoids and human basophil histamine release.” Int. Archs Allergy appl. Immun. 1985;77:155-7.
11. Yoshimoto, T. et. al., “Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase.” Biochemical and Biophysical Research Communications 1983;116(2):612-18.
12. Della Loggia, R., et. al., “Anti-inflammatory activity of benzopyrones that are inhibitors of cyclo- and lipo-oxygenase.” Pharmacological Research Communications 1988; 20(Supp. V):91-94.
13. Middleton, E., Suresh, A., “Quercetin inhibits lipopolysaccharide-induced expression of endothelial cell intracellular adhesion molecule-1.” Int. Arch. Allergy Immunol. 1995;107:435-6.
14. Taussig, S.J., Batkin, S., “Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application.” An Update Journal of Ethnopharmacology 1988;22:191-203.
15. Lotz-Winter, H., “On the pharmacology of bromelain: An update with special regard to animal studies on dose-dependent effects.” Planta Medica 1990;56:249-53.
16. Taussig, S.J., “The mechanism of the physiological action of bromelain” Medical Hypothesis 1980;6:99-104.
17. Ako, H. Cheung, A.H.S., Matsuura, P.K., “Isolation of a fibrinolysis activator from commercial bromelain.” Arch. Int. Pharmacodyn. 1981;284:157-67.
18. Afanas’ev, I.B. et. al., “Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.” Biochemical Pharmacology 1989;38(11):1763-69.
19. De Whalley, C.V., “Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages.” Biochemical Pharmacology 39(11):1743-50.
20. Beretz, A. Stierle, A., Anton, R. Cazenave, J., “Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin.” Biochemical Pharmacology 1981;31(22):3597-600.
21. Heinicke, R. van der Wal, L. Yokoyama, M., “Effect of bromelain (Ananase®) on human platelet aggregation. ”Experientia 1972;28(7):844.
22. Hollma, P. et. al., “Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers.” Am. J. Clin. Nutr. 1995;62:1276-82.
23. Giller, F.B., “The effects of bromelain on levels of penicillin in the cerebrospinal fluid of rabbits.” A., J. Pharm. 1962;134:238-244.
24. Bodi, T., “The effect of oral bromelain on tissue permeability to antibiotics and pain response to bradykinin; double-blind studies on human subjects.” Clin. Med. 1965;72:61-65



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Vitanet ®



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HDL and LDL Cholesterol


Date: June 25, 2005 07:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL and LDL Cholesterol


HDL and LDL Cholesterol

There are both “good” and “bad” forms of cholesterol. The “good” form of cholesterol is found in the form of high-density lipoproteins (HDLs). The ‘bad” forms of cholesterol are the low-density lipoproteins (LDLs). The types of fats we eat influence how much and what type of cholesterol we make. Saturated fats are particularly good at Raising low-density lipoprotein or LDL cholesterol. The more of this type of cholesterol we have floating around in our bloodstream, the greater our risk of developing atherosclerosis, heart attack and stroke. The more HDL cholesterol we have (high-density lipoproteins) the lower our risk of coronary heart disease.

The liver is constantly trying to clear out the bad cholesterol by dumping it into the intestines. If we have sufficient amounts of the right kinds of fiber in our diet, our bodies dispose of cholesterol waste rather than reabsorbing it back into the blood stream. If we don’t eat sufficient amounts of the right kinds of fiber, the cholesterol waste is reabsorbed and adds to the toxic stress on the body—especially the liver.

The obesity factor is emerging as much more important than previously thought.23, 24 New findings strongly suggest that even a relatively small amount of excess weight (between 10 and 20 pounds) can predispose one to the development of heart disease.25

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SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH CAPSICUM


Date: June 23, 2005 11:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH CAPSICUM


SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH CAPSICUM

The following are specific actions associated with capsicum and the conditions it can help relieve.

• • can help to stop both internal and external hemorrhaging
• • facilitates the healing of ulcers
• • high flavonoid content makes it a good antioxidant
• • boosts heart action without Raising blood pressure
• • improves the ratio of HDL to LDL cholesterol
• • supports vessel and capillary elasticity
• • helps to protect against heart disease and stroke
• • may help to minimize damage from heart attack or shock
• • works to re-build and heal injured stomach tissue
• • rich in vitamin C, it strengthens the immune system
• • promotes better digestion by boosting HCL secretion
• • acts to equalize blood pressure
• • may help to increase thermogenesis or the burning of fat
• • topical use relieves pain of arthritis, surgical scars, shingles etc.
• • used on the skin, may help to protect against frostbite
• • serves as a powerful catalyst for other herbs
• • helps to relieve psoriasis

  PRIMARY MEDICINAL APPLICATIONS OF CAPSICUM

• appetite stimulant arthritis
• asthma atherosclerosis
• bleeding (internal and external) blood pressure
• bronchitis burning feet
• chills circulatory disorders
• colds congestion
• depression diabetic neuropathy
• fatigue frostbite (prevention)
• heart ailments heart attack
• hemorrhage indigestion
• infection laryngitis
• migraines (cluster headaches) mouth pain
• nausea nosebleeds
• general pain phlebitis
• pleurisy psoriasis
• rheumatism shock
• sore throat strokes
• tennis elbow tonsillitis
• toothache ulcers
• varicose veins wound bleeding

  Substances that Complement Capsicum As previously mentioned, Capsicum is frequently added to herbal combinations in order to boost and potentiate their action.

  The following herbs create particularly good herbal complements with Capsicum: garlic, ginger, hawthorn berry, peppermint, myrrh, yucca, gotu kola, parsley, ro s e m a ry, echinacea, kelp, ginseng, ginkgo, bayberry, slippery elm, black walnut, papaya, pep- permint, fennel, St. John’s Wort, and lobelia.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=408)

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  CLA and Cows
  

  Date: June 22, 2005 09:52 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: CLA and Cows
  

  CLA and Cows

  Nutritional developments like that of CLA couldn’t come at a better time. America is a nation obsessed with weight, but successes in battling weight seem harder and harder to come by. Is there a nutritional reason for this? Have we been barking up the wrong tree in recent years, starving ourselves for fear of gluttony rather than looking at broader nutritional reasons for fat accumulation? For example, Dr. Cook says that modern nutritional dogma is that fat is bad. “I’m not sure the dogma’s right. We need to get down to very specific fatty acids.”51 One of the most exciting developments coming from CLA research is that modern animal-Raising techniques may be partially responsible for those of us who eat meat getting fat around the middle, even though our consumption of meat may have declined or, at least, stayed about the same in recent years.

  CLA has been declining in our diet. This one nutrient’s lack may mean many of us are gaining fat, despite eating less overall fat.52

  This desire to simply eliminate fats without looking at the broader nutritional picture has its roots deep in our culture. The desire to starve ourselves to lose weight goes back centuries. We have often thought weight gain came solely from lacking self-control when, often, nothing could be further from the truth.

  Take for example the experiences of conscientious objectors during World War II. These men who chose, for religious reasons, not to fight in the war, contributed in other ways. One group at the University of Minnesota underwent forced starvation to help scientists learn ways to help concentration camp victims recover after liberation.

  Science learned many useful things, but one thing stands out. The objectors grew more hungry as they recovered and ended up weighing five percent more after they recovered than before the experiment began. (The same can be said for refugees and concentration camp victims, who also weighed more, on average after their ordeals than before.)53 This idea of dieting being the full answer to weight loss still persists, often tragically. Many have died of anorexia, obsessed with self-image. Others have died directly from ill-conceived meal replacement programs.54 In the 1980s, Americans spent $15 billion on diet soft drinks alone,55 but consumers weighed more on average when the decade was over than when it began. You’d think all of this energy and dieting spent on the effort would have helped people lose weight. (Thankfully, many people have succeeded in losing weight and keeping it off. According to Dr. Pariza, this may well be the most significant part of CLA, not so much in losing the weight, but in helping people keep it off.56)

  To drive the point home further, consider your parents. They ate a diet that was likely higher in fat than yours. They never saw “lite” versions of snacks in the store. Yet they, in general, weighed less than we do. Why? Surely exercise may have had something to do with it, but, no one has the complete answer. It seems likely that nutrition too played a role. CLA itself may hold part of the reason. As we have seen, CLA nutrition means less fat and more protein in our bodies. Recent research is showing that the amount of CLA in cows has dropped substantially since the times of our parents. In 1963, scientists found that CLA was as much as 2.81 percent of milkfat. The amount of CLA in the milk products varied with the seasons. At some times during the year, cows ate grass. At other times, they ate feed. However, in 1992, Pariza and his colleagues did a large food survey and found that this variation in CLA is no longer occurring. Furthermore, the amount of CLA in dairy products rarely gets above 1 percent of the milkfat. 57

  In another research paper in 1994, scientists noticed that Australian cows have as much as three or four time the amount of CLA in the meat from similar American animals. Why? These differences probably “reflect different feeding conditions.” 58

  Today, farmers use more efficient feeding methods that rely less heavily on natural grasses. This means less CLA in the meat we eat, and less CLA can mean a higher percentage of fat on our bodies. Consider too that skim milk contains virtually no CLA with its no fat content. This lack of CLA may actually hinder some people’s efforts to lose weight.

  The lesson here seems to be that gluttony guilt would be better focused on balanced living. Healthy lifestyles coupled with the right supplementation can make a difference. CLA, though no magic bullet, adds to this lifestyle and could be the key that finally opens many weight (and fat) management doors. It could help many people keep the weight off.

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  Marilu Henner: Energy Personified!
  

  Date: June 14, 2005 11:50 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Marilu Henner: Energy Personified!
  

  Marilu Henner: Energy Personified! by Stephen Hanks Energy Times, January 3, 2005

  Marilu Henner is an actress, dancer and author, a health, fitness and cooking guru and a devoted mom. Now she's also an advocate for nutritional supplements. In this revealing interview, she offers her thoughts on the battle to support consumer rights and to create a better health care system in America.

  "So, you want to know what my schedule is after I finish talking with you?" Marilu Henner says, in an almost breathless voice. "Today's Tuesday, right? Tomorrow morning I leave Los Angeles [where she lives] for New York City so I can do the Tony Danza Show first thing Thursday morning, Then, I take a 9 am flight back to LA because my son has a sleepover birthday party. I have a 7 am flight to New Jersey the next morning because I'm speaking about mental health at a conference at a big country club. The next morning, I catch a 7 am flight back to LA for my son's soccer games, one at noon and the other at 2. Whew!"

  Trying to keep up with Marilu Henner would make anybody feel out of breath because the woman is energy personified. At 52, her schedule includes acting in movies, on television and in the occasional Broadway show, writing books (she's authored seven, including Total Health Makeover and Healthy Life Kitchen), teaching online diet and exercise classes through her website (marilu.com), taking Pilates classes three times a week and Raising two sons, Nicholas (10) and Joseph (8).

  But now, on top of all that, the former star of the TV show Taxi has become a health and nutrition activist, speaking out in favor of the use of dietary supplements whenever she can. This past September, Henner testified at a hearing of the House Subcommittee for Human Rights and Wellness to advocate increased funding for research and full implementation of the Dietary Supplement Health and Education Act (DSHEA). During her testimony, Marilu described why she believes consumers should have access to more information about supplements and why the products should be made more accessible through both government initiatives and private health plans. "I believe that dietary supplements should be part of a campaign to improve our nation's health," Henner testified.

  Energy Times recently caught up with Marilu at her Los Angeles home for a freewheeling conversation. Here, this vibrant yet down-to-earth celebrity displays her passion for health, nutrition and consumer issues.

  Energy Times: You've become one of the most high profile celebrities to advocate a consumer's use of dietary supplements. What was your motivation to get involved in such a public way?

  Marilu Henner: As a teenager, I had been a yo-yo dieter. I could be around 135 pounds and balloon up to 174. I knew I needed a different way of looking at my life. I couldn't concentrate on those stupid diets where I could lose 20 pounds in a week and then gain it all back over a weekend. But after my mom died at 58 in 1978, I said to myself, "It's not really about my body anymore, it's really about my health." I just became obsessed with health. I read everything I could get my hands on. I starting taking human anatomy classes, going to medical libraries and seeing nutritionists and doctors. And I started experimenting on myself, turning myself into my own guinea pig. It took me about eight years to put together a program. I always say that my health birthday was 1979, but it wasn't until 1987 that I could say I was living a completely healthy lifestyle.

  ET: Were you ever really heavy when you were performing in a show? MH: Sure. When I first performed the role of Marty in "Grease" more than 30 years ago I weighed about 175 pounds. But I hid it well. When you wear those 1950s clothes you can get away with it.

  ET: When did you start incorporating supplements into your health program? MH: Before I became pregnant with my first son in 1993, I had never been a supplement taker. But I started taking prenatal vitamins and dietary supplements when I was breastfeeding and they made me feel really good. After the pregnancy, I just kept taking them because I was getting the essential nutrients that I couldn't get from food alone. I was getting great stuff from my food, but with all the travel I do-you know, the eating on planes and in restaurants-I couldn't always shop for organic food. I had a doctor who understood the value of dietary supplements and encouraged me to use them. I've taken them ever since and I recommend them to my family and friends, as well as to people through my books and classes.

  ET: What supplements other than vitamins do you find helpful in your total nutrition program? MH: I take vitamin E, omega-3 fish oils, antioxidants, garlic, coral calcium and echinacea supplements.

  ET: So let's get back to why you decided to testify before Congress in support of supplement use. MH: I know that as soon as you put a celebrity face on an issue, people tend to pay a little more attention. When I was in Washington, I was able to tell Congress the personal stories I've heard about people who turned their lives around-from debilitating illness to vibrant health-when they got the information they need to make good choices. By good choices, I mean rejecting the manufactured foods of our society, with their over-reliance on sugar, meat and dairy, and the chemicals, hormones and steroids that usually accompany these products. Instead, we should be moving towards an organic, vegan diet that produces a sense of physical health. I also believe that a healthy diet includes the use of appropriate dietary supplements.

  ET: Do you think that government is moving fast enough to reduce the restrictions on safe supplements? MH: Things could always move faster. But I remember years ago writing letters on behalf of people who wanted supplements without needing a prescription. When I would tell people about the benefits of soy products or supplements, they'd think I was nuts. Now those ideas are mainstream. The floodgates are open and people want to know more. You can't even keep up with all the information. I think that the government knows they're not going to get away with making people have a prescription to take their vitamins.

  ET: What is the citizen's responsibility in all this? MH: We're in a real transitional phase and people should take responsibility to educate themselves. You have to question your doctors and recognize when something is or isn't working. You have to find a health practitioner who really knows their stuff.

  ET: As you said, there's so much information out there, how do you decipher it all? How can someone be an educated information consumer?

  MH: I know it's very difficult because there are so many options. Believe me, I've been doing this a long time and I'm glad I did the research. I think you have to read everything. You have to find a nutritionist/herbalist/doctor who's the real deal and knows what they're talking about. You have to recognize the symptoms in your own body and try to figure it out. I think if you start out with a good multivitamin, a calcium supplement, fish oils and vitamin E, that can be your base and you can't go wrong.

  ET: Isn't a diet built on buying organic foods much more expensive? MH: Sure, it's a little more expensive. But there's nothing more expensive than bad health. There's nothing more expensive than food being thrown away because it doesn't taste right. Organic fruit tastes so much better than the perfect-looking fruits and vegetables sprayed with pesticides.

  ET: What's your advice to people who want to start a workout and weight-loss program? MH: I'm always saying to people, "Look, you walk your dog, your cat stretches, your hamster runs on a hamster wheel. You're an animal, too, so go move, go do something." I know a lot of people believe that when you want to lose weight you have to go on these 1,200-calorie-per-day diets.

  Well, my weight is always between 120-124 pounds and I eat close to 2,000 calories a day, but everything I eat is of quality. And I burn a lot of calories because I wear comfortable shoes and I move around in my life. I'm always strong, I never get sick and I feel like an animal.

  ET: How do you view the future of healthcare policy in this country and where do you think nutritional supplements fit in? MH: I strongly believe that the general public needs more access to dietary supplements to maintain essential good health. American research and development has come up with really great products, but the American Medical Association and the drug companies have stigmatized supplements. So what's the result? Most Americans don't have access to safe supplements because they are not covered by their health plans, nor recognized as effective by the federal government. This really needs to be changed.

  I think we should take 90% of what we're spending on drugs that barely keep people alive and start spending it on prevention, nutrition and changing lifestyle habits. In this country we're all about curing the disease rather than curing the patient. We don't look at the patient holistically and try to find out how the disease developed. Your doctor should be in charge of keeping you well, not keeping you in that strange state of, what I call, "dis-ease." It's like the medical and pharmaceutical establishment wants to keep you just sick enough so you'll continue to be a paying customer. They've convinced people to think they've got to take a pill to cure themselves rather than use their own bodies.

  ET: Do you think medical schools will start training doctors to treat patients holistically and focus more on preventative medicine?

  MH: I think we're seeing a lot more nutrition and alternative medicine specialists these days. And the general public is becoming more aware of health and nutrition issues then they were years ago. There's this groundswell of people saying "Wait, I need more information. Wait, my doctor's no longer God. I can't just keep taking these pills and trying to figure out all these warning labels and side effects."

  ET: Do you plan on becoming more politically active on these issues? MH: Absolutely, I want to work with any organization that wants to improve school lunch programs, improve the healthcare system and get people more involved in understanding nutrition and disease prevention.

  
  
  --
  Vitanet ®
  
  

  Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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  Mane Attraction - lustrous Hair...
  

  Date: June 14, 2005 08:19 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Mane Attraction - lustrous Hair...
  

  Mane Attraction by Chrystle Fiedler Energy Times, February 12, 2004

• The Nature of Hair
• Hair's Natural Nutrients
• Ancient Chinese Hair Secrets
• Revive Hair Glow
• Go Natural

Everyone wants thick, lustrous hair. Think of the allure attached to the locks of Samson and Lady Godiva and-fast-forward to the present-the full heads of Antonio Banderas and Julia Roberts.

" We're naturally attracted to hair as humans; it catches the light, it frames the face, we like the feel of it," says Catherine Jones, ND, LAc, a resident naturopathic physician at Bastyr Center for Natural Health in Seattle, Washington. "Fair or not, historically in many cultures, rich, thick hair has been a sign of fertility and strength."

Along with that allure, latching onto natural ways to have great-looking hair gives you the benefits of looks and health. Every hair starts with a shaft that grows from a root. "The root is contained deep within the hair follicle," says Dr. Jones. "Each one has a sebaceous or oil gland, which supplies the hair with necessary lubrication as it approaches the surface of the scalp." Each hair follicle has its own growth cycle, including a resting period, the telogen phase, when hair falls out. Because of these constant hair phases, each of us loses, on average, about 100 hairs a day.

" The number of hairs the average person loses in a day tends to increase in the fall as the leaves fall from the tree and tends to decrease in the spring as the bulbs emerge from the soil," Dr. Jones says. "We really are connected to nature." Stress-due to rapid weight loss, infection, anemia, prolonged illness, hormonal changes, hypoactive thyroid disease, autoimmune conditions, eczema or psoriasis-can influence hair growth and loss.

The Nature of Hair

Hair consists of proteins, lipids (fats), carbohydrates and pigment (gray hair has reduced pigment; white, none at all). Each shaft's structure is divided into a medulla, a cortex and an outer cuticle. " The cuticle is coated with an outside lipid-like layer, which protects the hair," says Dr. Jones. "As the hair grows out of the follicle, the cortex and cuticle become keratinized and harden." Dry or damaged hair is more susceptible to breakage. "The condition of the cuticle affects how the light reflects off the hair, giving it highlights and luster," Dr. Jones says. "Luster is affected both by what occurs inside the body as the hair is developing and what happens to the hair after it has grown from the shaft."

Sun, heat, moisture, pollution and hair products, dyes and bleaches can all dull the hair. "Applying chemical solutions to the hair, color, permanent waves or curl relaxers, damage the protein molecules that wrap around the shaft, leaving hair brittle and dull," says Christina Pirello, author of Glow: A Prescription for Radiant Health and Beauty (HP Books).

Conditioners and oils can leave a residue or weigh hair down. Hair sprays and products that contain alcohol can dry and damage the hair, as can using blow dryers and curling irons.

Hair's Natural Nutrients

To combat hair-Raising havoc, feed your hair natural nutrients for health. Silica and plants that contain silica/silicon both strengthen hair and promote growth. "Silica is a good mineral for hair health," says Walter Siegordner, founder of The Aurora Group, a personal care company. "It helps in the keratinization process of the cells that produce hair."

" Silica is a mineral that is involved in the synthesis of bone and connective tissue," adds Dr. Jones. "The hair follicle contains connective tissue so silica may promote the health and function of the follicle itself." Silica-containing herbs include nettles (Urtica dioica), horsetail (Equisetum arvense), oatstraw (Avena sativa) and alfalfa (Medicago sativa).

Sea plants like seaweed and kelp also provide vital nutrients. "Sea plants are essential ingredients in many natural shampoos and can be used to fortify damaged hair," says Pirello. "They're rich in vitamin A that prevents the build-up of dead skin cells, which can clog the hair follicles, inhibiting the growth and health of the hair, and also contain vitamin B, linked to the prevention of oily hair, baldness and dandruff. Calcium found in sea plants is essential to the structure of the hair shaft."

Eaten on s daily basis, sea plants are rich in nutrients that help maintain healthy, shiny hair, free of split ends, Pirello says. Try wakame in soups and salads, kombu or kelp in bean and vegetable dishes, nori in sushi, and hiziki and arame as side dishes. Since hair health is affected by digestive health, the fiber found in whole grains also helps. "Fiber prevents accumulation in the intestines that can result in the formation of toxins," says Pirello.

Miso, she adds, is especially good hair food. It "is rich in living enzymes that ease digestion, fortify the quality of the blood nourishing the body and hair, and provide us with essential oils, vitamins and minerals."

Key nutritional support includes adequate protein and amino acids, essential fatty acids such as cold-pressed flax seed oil and fish oil, copper, vitamin A, vitamin E, vitamin D, biotin, iron and vitamin B5 (pantothenic acid). Zinc and selenium can help combat the effects of hyperthyroidism, which can result in thinning, lackluster hair.

Vitamin C can boost adrenal health. "When the adrenals are overtaxed and become fatigued, hair follicles will go into a resting phase," says Dr. Jones. (If you have a medical condition, she adds, check with your health care practitioner first before taking supplements.)

Ancient Chinese Hair Secrets

In Traditional Chinese Medicine, hair is associated with the kidneys' qi, energy that originates in these organs, and with blood quality. " From the traditional Chinese perspective, excess amounts of fat, protein, dairy, sugar, alcohol and salt in the diet acidify the body, damage the Kidney qi and are not good for the hair," says Dr. Jones. A diet rich in vegetables and grains is a great way to support healthy hair. "Iron and mineral-rich foods are considered blood builders and hair tonics. Foods such as blackstrap molasses, seaweed, nettles, and the herb polygonum multiflorum (also known as He Shou Wu and Fo-Ti) have been used throughout the years. Fo-Ti has also been used to prevent graying of the hair and support the immune system."

Revive Hair Glow

" Hair is extremely strong but at the same time it's extremely delicate," says Barsoum Bouchar, a cosmetologist and owner of the Virtuoso Salon in Birmingham, Michigan. "Many products work against the hair texture, so the cuticle is always raised. This causes tangles and split ends. With blow dryers, chemicals, colors and styling elements, the hair is tremendously abused." If you don't have to chemically treat the hair, he says, don't.

When replenishing the hair it's important to remember that it's composed of 97% protein and 3% moisture, says Bouchar. Shampoo cleanses the hair and removes buildup. "A moisturizer brings moisture back into the hair and smoothes the cuticle down, which is what makes hair shiny and gives it bounce. The one key ingredient in both shampoo and moisturizers is aloe vera. It heals the hair." " Avoid products with harsh surfactants like sodium laurel sulfate and propylene glycol," warns Siegordner. "These decrease the circulation in the scalp, reducing the pathway for nutrition to the hair bulb." Conditioners that aren't natural can also cause build-up. "When you apply heat to the hair through blow drying or styling, you end up 'burning' the hair," says Bouchar.

To stimulate hair growth, add a few drops of essential oils of rosemary, lavender and thyme to jojoba and almond oils, and rub into the scalp. Leave it overnight and then rinse it off. " Essential oils have antimicrobial and antifungal properties, stimulate the circulation to the hair follicles and combat dryness. They also smell good," says Dr. Jones.

For hair that's not chemically treated, "a vinegar rinse cleanses the hair, removes build-up and boosts shine," says Bouchar. Use one part vinegar to ten parts water, apply after a shampoo, comb though and rinse it off. To naturally lighten the hair, use the same ratio in a lemon rinse for five minutes for, say, four days in a row, and then stop.

If you want to color your hair, choose natural elements, too. "The best natural dye is henna," says Bouchar. "It's organic, just like hair is." Blonde hair becomes warmer with a coppery tone, brunette hair takes on a mahogany hue, gray hair looks like highlights.

Go Natural

To find a good natural hair stylist, Bouchar suggests asking which products they use and why. If your hair is chemically treated, it's especially important to work with a stylist you trust for the best care.

Keep your eye on the big picture when it comes to hair health. "Be proactive and treat the body holistically," urges Dr. Jones. "Nourish the glands, the organs and the vessels that are responsible for getting the necessary nutrients to the hair follicle. Pay attention to the physical, emotional and mental aspects of health. Once hair is lost it may come back but it will likely be thinner than it was before. It's important to take care of what you have."



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Vitanet ®



Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Power Protein


Date: June 11, 2005 05:04 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Power Protein


Power Protein by Joanne Gallo Energy Times, August 4, 1999

Chances are, if you've been trying to lose weight, build muscle, or increase your energy levels, then you've been hearing about protein. This essential nutrient has stolen the spotlight of the health industry as the alleged key to vitality and a solid physique.

With books like Protein Power (Bantam) and Dr. Atkins' New Diet Revolution (Avon) firmly implanted on The New York Times bestseller list, and protein bars and shakes growing in popularity, more people than ever are seeking to tap into the power of protein.

But before you go on an all-out protein-blitz, how can you decide what's best for you?

The Purpose of Protein

No doubt about it, protein performs a variety of roles. First and foremost, it is used to manufacture and repair all of the body's cells and tissues, and forms muscles, skin, bones and hair. Protein makes up the connective tissue that forms the matrix of bones; keratin is a type of protein used to make hair and nails.

It is essential to all metabolic processes; digestive enzymes and metabolism-regulating hormones (such as insulin, which influences blood sugar levels) are all made of protein. This nutrient also intricately takes part in transport functions: Without sufficient protein the body cannot produce adequate hemoglobin, which carries nutrients through the blood. Lipo-proteins are fat-carrying proteins which transport cholesterol through the bloodstream.

Protein helps regulate fluid and electrolyte balance, maintaining proper blood volume. Immunoglobulins and antibodies that ward off diseases are also comprised of protein.

Any protein that you eat that is not utilized for these purposes is stored as fat, although some may be broken down, converted to glucose and burned for energy. This can occur during intensive workouts, or when the body runs out of carbohydrates from the diet or glycogen from its muscle and liver stores.

"Even though the body can depend on the fat it has stored, it still uses muscle protein, unless it is fed protein as food," explain Daniel Gastelu, MS, MFS, and Fred Hatfield, PhD, in their book Dynamic Nutrition for Maximum Performance (Avery). "When dietary circumstances cause the body to use amino acids as a source of energy, it cannot also use these amino acids for building muscle tissue or for performing their other metabolic functions."

One can see why it is so important to eat a sufficient amount of protein daily in food, shakes or bars. Without it, bone tends to break down, the immune system can become impaired, and muscle strength drops as the body uses up muscle protein for energy.

Acid Trip

Proteins are built of chains of amino acids, and 20 different kinds of these building blocks are necessary for protein synthesis within the body. Eleven of them can be manufactured by the body through a process called de novo synthesis; these are referred to as non-essential amino acids. The other nine, which must be obtained from the diet, are known as essential amino acids. (Although some amino acids are called "non-essential," in actuality they are vital: The body needs all 20 amino acids to function properly.)

Some of the more familiar non-essential amino acids include: n Carnitine helps remove fat from the bloodstream n Arginine helps burn sugar Essential amino acids include: n L-tryptophan, a precursor of the neurotransmitter serotonin, helps create calm moods and sleep patterns n L-lysine, required for the metabolism of fats n L-methionine a component of SAM-e (a supplement intended to relieve depression and arthritis, see p. 45)

The body forms and destroys protein from amino acids in a constant cycle of synthesis and degradation. You must consume protein regularly to replace the lost amino acids that are oxidized when protein is broken down and used for fuel. The amount of amino acids lost each day depends on what you eat and how much exercise you do.

Athletes vs. Weekend Warriors

Protein intake in the general population is still adequate, notes Gail Butterfield, PhD, RD, director of Sports Nutrition at Stanford University Medical School. "But we're learning that what is true for the general population may not be true for the athletic population," she says. "With heavy training there is greater protein degradation and you need to increase your intake. Thus, protein requirements are higher for athletes than regular people."

Also, if you diet or restrict your eating in any way, you may also not be getting enough protein.

Certainly, if you work out, eating protein is important. Providing four calories of energy per gram, protein keeps blood sugar steady during exercise. After exercise, it helps replenish and maintain stores of glycogen (stored muscle fuel) and decreases the loss of amino acids, as recent research has shown (J Appl Physiol 81 (5), Nov. 1996: 2095-2104). Lab studies in animals show that protein consumed after you run, lift weights, bike, etc..., helps stimulate muscle growth (Jrnl of Nut 127 [6], June 1997: 1156-1159)

High-protein diets are frequently touted to promote weight loss and increased energy. One of the most influential: the so-called 40-30-30 formula, developed by Barry Sears in his book The Zone: A Dietary Roadmap (HarperCollins), which describes a diet whose calories are 40% carbohydrates, 30% protein and 30% fat. The rationale: when you eat too many carbohydrates, your body uses these starches for energy instead of burning body fat. A high protein diet is supposed to keep your blood sugar balanced and stimulate hormones that burn body fat instead of carbohydrates for energy.

Other fitness experts such as Sherri Kwasnicki, IDEA International Personal Trainer of the Year of 1998, say that while protein is a necessary component of any diet, extreme high-protein plans aren't necessary for recreational fitness buffs. However, she notes that maintaining muscle mass is the key to aging gracefully, and getting enough protein is critical for that.

Protein Sources

Many people today won't eat meat and dairy for ethical reasons, or to avoid the antibiotics and other chemicals in the Raising of poultry and cattle. But that doesn't have to prohibit adequate protein intake. All soybean products, including tofu and soymilk, provide complete proteins, which supply ample quantities of all the essential amino acids.

Vegan Power

In the past vegetarians were told to combine particular foods to make sure they consumed all the essential amino acids at each meal. (For example, beans with either brown rice, corn, nuts, seeds or wheat forms "complete" protein.) Today, diet experts aren't so picky. Eating a variety of plant-based foods throughout the day is just as effective as combining them at one meal.

Vegans who avoid all animal products should eat two servings at sometime during the day of plant-based protein sources, such as tofu, soy products, legumes, seeds and nuts.

Protein On-The-Go

The newest sources of protein are bars and shakes, which are growing steadily in popularity. Protein bars now constitute about 12% of the so-called energy bar market, with sales increasing about 38% per year. These bars generally provide at least 20 grams of protein, including soy and whey protein and calcium caseinate (milk protein). The benefits: bars supply protein along with carbohydrates for energy; protein powders, on the other hand, provide quickly digested, easily absorbed amino acids.

Edmund Burke, PhD, author of Optimal Muscle Recovery (Avery), suggests "If you need extra protein, you may benefit from the convenience of a mixed carbohydrate-protein supplement... choose a supplement that's healthy and low in fat."

Amino acid supplements are also growing in popularity, reported to build muscle and burn fat, or improve mood by boosting brain neurotransmitters. The amino acids glutamine, phenylalanine, tyrosine and 5-HTP (a form of tryptophan) are all used to boost spirits and enhance brain function.

And if you still ponder the merits of those high protein diets, do keep in mind that protein may be better at controlling hunger than carbohydrates or fat since it steadies blood sugar, so it may help you stick to a reduced-calorie plan. But excess protein can't be stored as protein in the body: It is either burned for energy or converted to fat. And carbs are still the body's top energy source, so forgoing too many can leave you tired and sluggish.

Still, with so many vital functions-and a variety of sources to choose from-you can't afford to not explore the benefits of protein.



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Vitanet ®



Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Thanks for the Memory


Date: June 11, 2005 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Thanks for the Memory


Thanks for the Memory by Estelle Sobel , February 6, 2002

Thanks for the Memory By Estelle Sobel

"I feel like every day, I lose my memory more and more. It started when I couldn't find my car keys, sometimes I forget directions. My mother has Alzheimer's so I'm concerned," says Jerry Solowitz, a 63 year old man.

Ellen Lerner, 37, sometimes worries that she can't keep track of everything in her job as a public relations executive. "I feel like stress can get to me easily, and I worry because I forget simple things like where I put a file."

Should these people be concerned?

"Yes," says Lynda Toth, Ph.D., co-author with Pavel Yutsis, M.D., of Why Can't I Remember? Reversing Memory Loss (Avery, 1999).

Jerry should start a specific program with a health practitioner who specializes in memory loss, due to lots of unsuspected new causes for memory dysfunction. Ellen needs to make lifestyle changes, as stress can definitely lead to memory loss.

"Cortisol, which is one of the stress hormones, can be harmful because it keeps calcium in the memory pathway too long and destroys the neurons, which is very damaging to the brain," notes Toth.

Why Does Memory Fail?

Memory fails for several reasons, says Augustine DiGiovanna, M.D., author of Human Aging: Biological Perspectives, (McGraw-Hill 2000), and Professor of Biology at Salisbury State University in Salisbury, MD.

Normal Aging: Much of diminished memory as we age is due to reduced blood flow to the brain from atherosclerosis, which is hardening and narrowing of the arteries. Decreased blood flow causes neurons to shrink and function less effectively.

Also, as we age we lose neurons and neuron connections that can lead to memory loss. So the way people think, how much they remember, and the mental activities they do determine how many brain cells survive through the years.

Finally, as people live longer, the chance is greater that the body's immune system and other defense mechanisms won't be able to protect against certain diseases that affect the brain and memory (Parkinson's, strokes, Alzheimers, atherosclerosis).

A Starving Brain: The brain is not getting fed the nutrients it needs (vitamins, minerals, amino acids, glucose). Without the right "food" the brain's energy levels become lowered and stop powering the memory cells. Then, free radicals can do more dirty work and continue to rust memory cells.

Drink And Sink: Alcohol passes through the blood-brain barrier and slows down the processing of information between memory neurons. Memory loss increases over time, as memory tissues shrink.

Sad Stories: Depression can imbalance the neurotransmitters and electrical charges of neurons.

Tense and Tight: High blood pressure can constrict and narrow blood vessels, limiting blood and oxygen flow to the brain.

Memory-Sustaining Supplements

One way to boost brain power is to take the right supplements.

Ginkgo biloba: The powerful medicinal herb ginkgo biloba increases blood flow and circulation to the head by dilating blood vessels in the brain, allowing more oxygenated blood to get to the neurons. It also protects against free radical damage.

Research: Ginkgo biloba extract displayed a significant effect on helping the mental abilities of people 50-59 years old (Phytotherapy Research 13, 1999: 408-415).

Pregnenolone: This powerful hormone regulates the balance between excitation and inhibition in the nervous system and helps enhance memory and brain function, possibly by repairing a fatty substance that is part of the myelin sheath that surrounds nerve cells. Research: A St. Louis University School of Medicine study on mice showed that pregnenolone enhanced memory and helped mice to navigate mazes better.

Huperzine A: This herbal supplement is derived from club moss found in China; in purified form it inhibits the enzyme that breaks down acetylcholine, a neurotransmitter produced in the brain that you need for memory.

Research: Studies conducted by Alan Mazurek, M.D., found that huperzine A in purified form improves memory, enhances focus and concentration and has been used to improve memory loss in Alzheimer's patients (Alt. Ther. in Health Med. 5 [2], March 1999: 97-98).

Another study in The Journal of Neuroscience Research showed that huperzine A is a potent inhibitor of cholinesterase, which penetrates the brain and produces a dose-dependent increase of the neurotransmitters acetylcholine, norepinephrine and dopamine in rat cortex (41, 1995: 828-835).

Phosphatidylserine (PS): This substance, which occurs naturally in nerve cell membranes, helps keep fatty substances soluble and cell membranes fluid and helps reduce levels of cortisone which are damaging to tissues.

Research: Phosphatidylserine encourages a sense of calm by Raising the levels of alpha brain waves and increasing the production of acetylcholine (Neuropsychobiology 24, 1990-1991: 42-48).

Vitamin E: This potent antioxidant attaches to bad cholesterol and helps prevent free radical damage to cells.

Research: Age-related processes like memory function and problem solving can be affected by free radical damage. Several studies show that vitamin E might slow the effects of Parkinson's disease and Alzheimer's disease (JAMA 282, August 18, 1999: 621). Acetyl-l-carnitine: Increases cognitive performance because it rejuvenates cellular membranes of mitochondria, the storehouses of energy contained in every living cell.

Alpha-Lipoic Acid: Preserves memory tissue by increasing glutathione levels, which protect fat stores in neurons from being damaged.

Nine Ways to Remember

Dr. Lynda Toth suggests the following ways to make the most of what you've now got.

1) Power Up Your Smile. Remove dental fillings and replace them with porcelain or ceramic ones. The mercury in metal fillings may be harmful (some believe) and can affect the brain and nervous system, inflaming memory tissue and preventing the entry of nutrients into the cells.

2) Don't Be a Tin Man/Woman Avoid exposure to aluminum. Don't use aluminum pots to cook in. Aluminum accumulates in memory tissue, damaging cells. In fact, autopsies of Alzheimers patients show they have unusually huge amounts of aluminum in the brain. But no one knows where this aluminum comes from.

3) Eat Right. Eat organic and pesticide-free foods. Pesticides get into the cells and can damage DNA.

4) A Matter of Taste. Avoid foods with artificial coloring, monosodium glutamate (MSG, often called "natural flavors" or "natural seasoning"). Also avoid processed foods with taste enhancers called exito toxins such as l-cysteine and aspartic acid.

5) In the Raw. Make sure that your diet consists of enzyme-rich 50% raw foods (fruits and vegetables) to feed the brain. Eat less animal fats.

* Drink green juices to support levels of the brain's clean-up enzymes.

*Eat lots of fiber, which helps remove toxins from the body. Pick up psyllium fiber.

*Limit intake of processed sugar, caffeine and alcohol to lessen the load on the liver and pancreas.

6) Cut Bait. Watch the fish that you eat. Lots of ocean and inland-caught fish are contaminated with mercury. Go for deep, cold water fish such as cod. Avoid shark and swordfish.

7). Oil Up. Supplement your diet with omega-3 fatty acids, such as cod liver oil or flaxseed oil. These fats lubricate memory cells.

8) Work That Body. Stay fit and exercise. Exercise helps oxygenate the body, reduces cholesterol, and builds and energizes new memory cells which reduces wear and tear on the brain function.

9) Do Mind Games. Read, listen to music. Tune into different radio stations than the ones you normally listen to. Do crossword puzzles and a wide selection of word games which can stretch your brain and give it a tough workout.

Student of Life

You need to keep learning your whole life to keep your brain and memory in tip top shape. The brain is adaptable, and you are always building new neurons, says Dr. Toth, which means that there is no limit to how long it can develop. Anything that stimulates the brain will help it to grow. That's why as you get older it's even more important to take classes, start a new hobby, travel. In fact, the challenge of learning and doing new things (without stopping in a fit of frustration) causes your brain to grow, says Dr. Mazurek.

The Good News

As people get older, their brains may actually improve and repair themselves through a complicated process that is designed to eliminate faulty neurons that are prone to making mistakes. At the same time, brain activity goes on that results in the development of new and improved connections with neighboring neurons.

Research also shows that memory improves if you train people to have faith in themselves. (The brain helps those who help themselves.) Apparently, a confident perspective can encourage the brain to actually improve to the point where its new-found abilities may increase to the point where it fulfills expectations.

So keep your chin up and stay away from the artery-clogging saturated fat that can cut off the brain's blood supply. It's all in the attitude, says Dr. DiGiovanna. And, of course, the key to a long and happy life with your brain is also on the end of your fork and in that bottle of supplements.

Estelle Sobel, is the co-author of Beautiful Skin: Every Woman's Guide to Looking Her Best at Any Age (Adams Media, May 2000).



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NATTOKINASE - A Systemic Enzyme for Healthy Circulation ...


Date: June 04, 2005 10:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NATTOKINASE - A Systemic Enzyme for Healthy Circulation ...


Nattokinase

You may not have worried about the effects of aging when you were younger. But now, you are interested in staying fit. Maintaining your cardiovascular health – for women as well as men – may be one of your greatest concerns. Every tissue in your body relies on your heart to circulate blood through approximately 60,000 miles of your blood vessels. This complex network requires a holistic health approach. Enzymes, which accelerate chemical reactions, can help with a lot more than just your digestion. Systemic enzymes are a special class of enzymes that work on every system in your body to support your overall health. Source Naturals has searched around the globe to bring you NATTOKINASE, a systemic enzyme from Japan that supports the fibrinolytic blood clearing system. Reach for NATTOKINASE to promote your cardiovascular health today.

Supports Healthy Circulation

Source Naturals introduces the science of NATTOKINASE, the natural way to support healthy circulation. A systemic enzyme derived from the fermented soy food natto, nattokinase supports your body’s mechanisms for clearing blood to maintain your cardiovascular health.

Systemic Enzymes

If you are a mature man or women, then maintaining cardiovascular health may be one of your greatest concerns about aging. Every tissue in your body relies on your heart to circulate six liters of blood through approximately 60,000 miles of your arteries, veins and capillaries. This complex network requires a holistic health approach. You might think that all enzymes are just for digestion. Actually, enzymes accelerate thousands of chemical reactions in your body. And systemic enzymes are a special enzyme class that work on every system in your body to support your complete, or systemic, health. Different systemic enzymes, such as papain, bromelain, pancreatin and nattokinase, each work in different ways. The results can include reducing cellular irritation, promoting clear blood flow and supporting balanced immune reactions for your shortterm comfort and long-term health.

An Ancient Japanese Health Secret

The legend about the discovery of natto begins thousands of years ago with Yoshiie Minamoto, a famous Japanese warrior, who was forced to pack hot cooked soybeans in straw for traveling. When the soybeans were later unpacked, the sticky mess was considered spoiled. But when the horses, notoriously picky eaters, preferred this soy food, then people began consuming natto and discovering its health benefits.

How It Works

Healthy circulation occurs when your blood flows smoothly. It takes complex cascades of events to maintain this cardiovascular balance. Source Naturals NATTOKINASE can help. NATTOKINASE doesn’t inhibit blood clot formation. Instead, it works to support healthy circulation in three ways. First, nattokinase assists the fibrinolytic blood clearing system by breaking down cross-linked fibrin protein deposits in the blood. Second, in preliminary studies, natto extracts promote clear blood flow by reducing Euglobulin Lysis Time (ELT). Third, nattokinase supports blood clearing by breaking down Plasminogen Activator Inhibitor–1 (PAI-1), an inhibitor of an enzyme that helps keep blood flowing. Lifestyle conditions such as high stress, high glucose levels and high amounts of adipose tissue are associated with increased PAI-1 levels. Healthy circulation can do wonders to support your total health. When your circulation isn’t balanced, then your tissues aren’t getting enough nutrients and your blood isn’t clearing enough wastes away, which can increase cellular irritation and decrease overall cell health. Alternately, systemic enzymes such as nattokinase support healthy circulation so your tissues can get optimal levels of nutrients delivered and wastes removed for your better health.

Lifestyle Strategies for Maintaining Cardiovascular Health

Eat a Healthy Diet: A diet low in cholesterol, saturated fats and trans-fatty acids, and high in complex carbohydrates and fiber is important for your cardiovascular health. Good choices include fruits and vegetables, whole grains, lean red meats, fish and poultry without skin (up to 6 oz per day), lowfat or fat-free dairy products, beans and peas, and healthy fats such as olive oil in limited amounts. Avoid sugar, which has been reported to increase risk factors linked to heart disease. Some healthy cooking tips include using a rack to drain off fat when you broil, roast or bake; using wine, fruit juice or marinades to baste; broiling instead of pan-frying; using a vegetable oil spray to brown or sauté foods; and cooking with egg whites instead of yolks. Exercise Regularly: Maintaining healthy cholesterol levels is important for supporting your cardiovascular system. Exercise may increase heart healthy HDL cholesterol and lower blood triglycerides (fats), partly because of the decrease in total body fat and increase in muscle mass that usually accompanies exercise. A recent study reported that dietary changes improve cholesterol levels only when an aerobic exercise program is also included. Regular aerobic exercises—brisk walking, jogging, swimming, biking, aerobic dance, and racquet sports—are the best forms of exercise for lowering LDL and Raising HDL levels. Experts recommend that people aim for a routine of 30 minute brisk walks most days of the week; an excellent goal is 20 to 25 miles a week, but in terms of Raising HDL levels, more is better. Resistance (weight) training offers a complementary benefit by reducing LDL levels. Quit Smoking: Cigarette smoking lowers HDL cholesterol levels and is directly responsible for approximately 20% of all deaths from heart disease. The toxic effects of cigarette smoke damage blood vessels in the heart and legs. In fact, smoking doubles an individual’s risk of heart attack with any level of blood cholesterol. The importance of breaking this habit cannot be emphasized enough. Drink Alcohol Only in Moderation: Many studies have reported that modest consumption of alcohol increases HDL levels and protects against heart disease and possibly stroke. However, since alcohol consumption can cause other health problems, you should consult your health care professional about alcohol use. It has been suggested that antioxidants in red wine such as flavonoids and polyphenols contribute to alcohol’s protective properties. Take the Right Supplements: Many supplements can help support your heart health. Folic acid, one of the B vitamins, supports arterial health by balancing homocysteine levels. Magnesium, potassium, and calcium all help to maintain heart muscle health. Antioxidants such as betacarotene, vitamin C, vitamin E, and those found in extracts of green tea support blood vessel integrity. And omega-3 fatty acids, such as those found in flax seeds, cod liver oil, and other dietary supplements support healthy blood flow. Additionally, you can take LIFE FORCE, Source Naturals’ best selling multiple. Systemic enzymes such as nattokinase are a new class of natural compounds that can have a significant impact on your cardiovascular, joint and immune health. Source Naturals is pleased to partner with your local health food stores and participating health professionals – the only places where you can find these natural health advances – to bring you NATTOKINASE. Try this ancient Japanese secret to support your cardiovascular health today.

References
Sumi, H. et al. (1990). Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematologica. (84): 139-143. Fujita, M. et al. (1995). Transport of nattokinase across the rat intestinal tract. Biological and Pharmaceutical Bulletin 18(9): 1194-1196. Yamamoto, K. et al. (2002). Plasminogen activator inhibitor-1 is a major stress-regulated gene: implications for stress-induced thrombosis in aged individuals. Proceedings of the National Academy of Sciences. 99(2): 890-895.



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Male Response - Re-align your body systems ...


Date: June 03, 2005 12:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Male Response - Re-align your body systems ...


Male Response

Between 10 and 15 million American men experience challenges to libido and sexual performance, according to the National Institutes of Health. Fatigue, stress, inactivity and an unhealthy diet can result in decreased vigor and desire. In addition, the normal aging process may result in a slowing of response, according to the National Institute on Aging. MALE RESPONSE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems that can negatively impact male sexual function: hormonal function, energy generation, circulation, the brain and nervous system, and the prostate gland.

Bio-Aligned Formula™

MALE RESPONSE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with male sexual function.

Hormonal Function

Hormones are chemicals released into the bloodstream that control numerous body functions. Testosterone is the most important of the male sex hormones. Produced by the testes, it is responsible for the development and maintenance of the male sex organs, contributes greatly to the level of sexual desire, and helps regulate energy and mood. MALE RESPONSE contains herbs and nutrients that may support hormonal function, including nettles, Panax ginseng, saw palmetto, tribulus, zinc, and vitamin B-5.

Energy Generation

Fatigue and poor energy can takes a toll on one’s desire or capacity for sexual intimacy. MALE RESPONSE combines a variety of herbs and nutrients to help revitalize energy levels, nourish the adrenals, and/or invigorate the sexual response. These include ashwagandha, Panax ginseng, Siberian ginseng, zinc, and vitamins B-5 and B-6.

Circulation

Proper circulation of blood is vital for male sexual response. MALE RESPONSE contains several herbs known for their effect on blood flow. For example, yohimbe contains yohimbine, an alkaloid from the bark of a native African tree, which can stimulate selected portions of the nervous system and increase blood flow to enhance the sexual response. Additional ingredients that support healthy circulation include ginger, ginkgo, and vitamin E.

Brain and Nervous System: Libido Stress and emotions often affect sexual desire and libido. MALE RESPONSE provides supportive nutrients for the healthy functioning of the nervous system, including copper, and vitamins B-5 and B-6. In addition, it contains herbs traditionally known for their aphrodisiac and/or rejuvenating properties. These include ashwagandha, avena sativa (oats), Panax ginseng, tribulus, and yohimbe.

Prostate Gland

A healthy reproductive system is an important part of a balanced approach to sexual function. Specific ingredients such as zinc support male reproductive health and are essential for the proper functioning of the prostate gland. Vitamin E, an antioxidant, supports normal prostate tissue functioning and sperm production. Additional support is provided by nettle, saw palmetto, and tribulus.

Lifestyle Tips for Healthy Male Response: A Strategy for WellnessSM

• • Eat well: Diet is perhaps the most significant single factor in generating virility. A diet rich in whole foods, with adequate protein from sources such as fish, chicken, turkey, lean beef, tofu or legumes, is crucial. The prostate gland contains high amounts of zinc, which is needed for sperm production and healthy testosterone levels. Foods high in zinc include seafood, meat, root vegetables, legumes, pumpkin seeds, nuts and whole grains. It is also important to follow a low-fat, low-cholesterol diet, since elevated cholesterol levels and the resulting buildup of plaque in blood vessels, can affect male reponse by impairing blood flow.
• • Stop using tobacco. Nicotine, tobacco’s active ingredient, constricts the small blood vessels, interfering with healthy circulation.
• • Use alcohol in moderation and avoid illicit drugs. Alcohol is a nervous system depressant, which can interfere with sexual function. Steady drinking can inhibit male response by inhibiting blood flow.
• • Get moving. Moderate, but not extreme, amounts of exercise help you relax, boost your energy levels, increase your physical awareness and ultimately stimulate your sexuality. Regular exercise has an impact on vasocongestion, Raising blood supply to the organs, while walking, stretching, swimming and resistance exercise help raise testoterone levels.
• • Contact a counselor. Counseling can help reduce the anxiety often associated with male performance. It can also address issues at work or home that may be contributing factors.

  Male Response is a Bio-Aligned Formula™ Multi-System Support for Sexual Vigor

  References
  Comas, M. et al. Bromatological study of maca. (Lepidium meyenii). Alimentaria 1997, 35(286): 85-90. Dini, A. et al. Chemical composition of Lepidium meyenii. Food Chemistry 1994, 49(4):347-9. Kapoor, L.D. Tribulus—indications and use. CRC Handbook of Ayurvedic Medicinal Plants. Boca Raton: FIAC/FASP; 1990. Physicians’ Desk Reference, 52 ed. Montvale, N.J.:Medical Economics Co.; 1998. Physician’s Desk Reference Medical Dictionary. Baltimore:Williams & Wilkins; 1995.

  
  
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  Gluco Sciense - Take Control of your Blood Sugar ...
  

  Date: June 02, 2005 10:51 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Gluco Sciense - Take Control of your Blood Sugar ...
  

  Gluco Sciense for Blood sugar

  Sedentary lifestyles, obesity, and sugar-rich diets are prevalent in our society. The result: challenges to your multiple, interdependent body systems involved with blood sugar levels and insulin activity. Now is the time to learn how a healthy diet and lifestyle can help you maintain healthy blood sugar levels. For further support, Source Naturals offers you GLUCO-SCIENCE™, a breakthrough formula. GLUCO-SCIENCE is uniquely effective because it is a Bio-Aligned Formula™. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance. GLUCO-SCIENCE can help bring your body’s systems for carbohydrate metabolism back into alignment.

• GLUCO-SCIENCE™ Maintains Healthy Blood Sugar Levels When Used as Part of Your Diet

  A Bio-Aligned Formula™

  GLUCO-SCIENCE is a comprehensive herbal-nutrient formula, based on the newest clinical research into key herbs and special ingredients. Source Naturals studied the scientific research, and then designed GLUCO-SCIENCE. This Bio- Aligned Formula provides targeted nutrition to five different body systems involved with healthy blood sugar levels and insulin activity.

  Glucose/Carbohydrate Metabolism

  GLUCO-SCIENCE supports glucose/carbohydrate metabolism with a range of nutrients. B-vitamins are required for glycolysis and the Krebs cycle, the metabolic pathways by which the body converts glucose into cellular energy. Chromium is believed to work closely with insulin to facilitate the uptake of glucose into cells. Manganese is also involved in glucose uptake. The formula also features herbs from several traditions, such as Gymnema sylvestre.

  Insulin/Pancreatic Activity

  Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. Certain nutrients (see chart) support these vital metabolic processes, including mediation of insulin release and activity, and enhancing insulin sensitivity. N-acetyl cysteine protects pancreatic beta cells from oxidative damage in animal studies. In addition, vanadium, zinc, and selenium are notable for their insulin-like actions.

  Heart and Circulatory System

  Vitamin E supports a healthy lipid status, while myricetin has been shown in animal studies to influence triglyceride levels. Gymnema sylvestre and vitamin C are involved with lipid metabolism. Additional heart-healthy ingredients include CoQ10, garlic, fenugreek, and hawthorn.

  Nervous System

  Antioxidants are important for a healthy nervous system. Lipoic acid helps prevent lipid peroxidation, which can impact nerve function. Many B-vitamins are vital to the metabolic processes of the nerves or are present in the phospholipids of cell membranes. Methylcobalamin, an active form of vitamin B-12, supports the central nervous system. Other supportive ingredients are included (see chart).

  Vision

  GLUCO-SCIENCE provides antioxidants, nutrients and herbs with an affinity for eyes and the physiological processes involved in sight. Alpha-lipoic acid, quercetin, and vitamin C support healthy lens function. Bilberry, shown to support microcirculation in animal studies, is widely recognized for supporting vision.

  Lifestyle Tips for Healthy Blood Sugar Levels: A Strategy for WellnessSM

• • Eat a Glucose-Healthy Diet: Fiber: Soluble fiber helps modulate glucose absorption and lowers plasma cholesterol levels. Adding 50 grams per day to your diet could help lower blood sugar up to 10%. Foods high in soluble fiber include oranges, grapefruits, Raisins, zucchini, oatmeal, oat bran, strawberries and apples. Viscous fibers, including guar gum, psyllium, and galactomannan can be helpful— they should be taken with liquid and mixed with carbohydrate foods. Protein: A high-protein, low-carbohydrate diet is associated with healthy blood sugar levels. Fat: Too much fat may increase your risk for heart disease and/or hardening of the arteries, which compromises circulation. Monounsaturated fats such as olive oil, however, are helpful for managing blood sugar. Glycemic Index: Avoid sugar and other foods with a high glycemic index. Different carbohydrates evoke different glycemic responses. Beans, peas, and oats, for example, raise blood glucose levels much less than bread and potatoes. The Glycemic Index, a useful educational tool in choosing foods to help modulate blood glucose levels, is available in the American Journal of Clinical Nutrition [1995;62:871S-93S (88)], or go to the Internet at www.mendosa.com/gilists.htm.
• • Maintain a Healthy Weight: If you are overweight, lose weight. Although a Body Mass Index (BMI) between 18.5 and 22 is considered “healthy,” problems arise at a BMI of 22, especially for women.
• • Exercise: Exercise lowers blood sugar and helps reduce risks associated with elevated levels, such as nerve and eye damage. Exercise also improves insulin sensitivity, and supports heart function and circulation. Try to get 20-45 minutes of aerobic exercise at least 3 days per week.
• • Maintain Healthy Blood Pressure Levels: If your blood pressure is 140 over 90 or higher, you are more likely to experience challenges to healthy blood sugar levels. Eat a “DASH Diet” containing 8-10 servings of fresh fruits and vegetables, 2-3 servings of low-fat dairy products and less than 2,400 mg of sodium per day.
• • Stop Smoking: Smoking raises glucose levels and aggravates related health problems.
• • Manage Stress: During stress, the level of many hormones increases and stores of glucose are released into your bloodstream, clogging and weakening vessels and capillaries. You can relax and reverse the hormonal response to stress by practicing deep breathing, meditating or doing yoga, exercising regularly, or talking with friends, family, or a support group.

  Help Maintain Healthy Blood Sugar levels with Gluco-sciense.

  Glucose/Carbohydrate Metabolism American Ginseng, Bitter Melon, Blueberry, Fenugreek, Gymnema sylvestre, Maitake, Myricetin, Pterocarpus marsupium, Chromium, Magnesium, Manganese, Vitamins B-1, B-2, B-5, B-6 & B-12, Biotin, Inositol, Niacinamide Insulin/Pancreatic Activity alpha-Lipoic Acid, Bitter Melon, Gymnema sylvestre, Maitake Fruit Body, Myricetin, N-acetyl-L-Cysteine, Pterocarpus marsupium, Taurine, Chromium, Manganese, Selenium, Vanadium, Zinc Heart and Circulatory System Bilberry, Blueberry, CoQ10, Fenugreek, Garlic, Grape Seed, Gymnema sylvestre, Hawthorn, Myricetin, Taurine, Siberian Ginseng, Magnesium, Selenium, Vitamins B-6, C & E, Folic Acid, Niacinamide Nervous System alpha-Lipoic acid, Glutamine, Magnesium, Taurine, Vitamins B-1 & B-6, Biotin, Choline, Inositol, Methylcobalamin Vision alpha-Lipoic Acid, Bilberry, Quercetin, Taurine, Zinc, Vitamins B-6, C & E

  
  
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  Date: May 20, 2005 05:33 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  

  Between 10 and 15 million American men experience challenges to libido and sexual performance, according to the National Institutes of Health. Fatigue, stress, inactivity and an unhealthy diet can result in decreased vigor and desire. In addition, the normal aging process may result in a slowing of response, according to the National Institute on Aging. MALE RESPONSE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems that can negatively impact male sexual function: hormonal function, energy generation, circulation, the brain and nervous system, and the prostate gland.
  

  Bio-Aligned Formula™ MALE RESPONSE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with male sexual function. Hormonal Function Hormones are chemicals released into the bloodstream that control numerous body functions. Testosterone is the most important of the male sex hormones. Produced by the testes, it is responsible for the development and maintenance of the male sex organs, contributes greatly to the level of sexual desire, and helps regulate energy and mood. MALE RESPONSE contains herbs and nutrients that may support hormonal function, including nettles, Panax ginseng, saw palmetto, tribulus, zinc, and vitamin B-5. Energy Generation Fatigue and poor energy can takes a toll on one’s desire or capacity for sexual intimacy. Male Response combines a variety of herbs and nutrients to help revitalize energy levels, nourish the adrenals, and/or invigorate the sexual response. These include ashwagandha, Panax ginseng, Siberian ginseng, zinc, and vitamins B-5 and B-6. Circulation Proper circulation of blood is vital for male sexual response. MALE RESPONSE contains several herbs known for their effect on blood flow. For example, yohimbe contains yohimbine, an alkaloid from the bark of a native African tree, which can stimulate selected portions of the nervous system and increase blood flow to enhance the sexual response. Additional ingredients that support healthy circulation include ginger, ginkgo, and vitamin E. Brain and Nervous System: Libido Stress and emotions often affect sexual desire and libido. MALE RESPONSE provides supportive nutrients for the healthy functioning of the nervous system, including copper, and vitamins B-5 and B-6. In addition, it contains herbs traditionally known for their aphrodisiac and/or rejuvenating properties. These include ashwagandha, avena sativa (oats), Panax ginseng, tribulus, and yohimbe.

  Prostate Gland A healthy reproductive system is an important part of a balanced approach to sexual function. Specific ingredients such as zinc support male reproductive health and are essential for the properfunctioning of the prostate gland. Vitamin E, an antioxidant, supports normal prostate tissue functioning and sperm production. Additional support is provided by nettle, saw palmetto, and tribulus. Lifestyle Tips for Healthy Male Response: A Strategy for WellnessSM • Eat well: Diet is perhaps the most significant single factor in generating virility. A diet rich in whole foods, with adequate protein from sources such as fish, chicken, turkey, lean beef, tofu or legumes, is crucial. The prostate gland contains high amounts of zinc, which is needed for sperm production and healthy testosterone levels. Foods high in zinc include seafood, meat, root vegetables, legumes, pumpkin seeds, nuts and whole grains. It is also important to follow a low-fat, low-cholesterol diet, since elevated cholesterol levels and the resulting buildup of plaque in blood vessels, can affect male reponse by impairing blood flow. • Stop using tobacco. Nicotine, tobacco’s active ingredient, constricts the small blood vessels, interfering with healthy circulation. • Use alcohol in moderation and avoid illicit drugs. Alcohol is a nervous system depressant, which can interfere with sexual function. Steady drinking can inhibit male response by inhibiting blood flow. • Get moving. Moderate, but not extreme, amounts of exercise help you relax, boost your energy levels, increase your physical awareness and ultimately stimulate your sexuality. Regular exercise has an impact on vasocongestion, Raising blood supply to the organs, while walking, stretching, swimming and resistance exercise help raise testoterone levels. • Contact a counselor. Counseling can help reduce the anxiety often associated with male performance. It can also address issues at work or home that may be contributing factors.

  References Comas, M. et al. Bromatological study of maca. (Lepidium meyenii). Alimentaria 1997, 35(286): 85-90. Dini, A. et al. Chemical composition of Lepidium meyenii. Food Chemistry 1994, 49(4):347-9. Kapoor, L.D. Tribulus—indications and use. CRC Handbook of Ayurvedic Medicinal Plants. Boca Raton: FIAC/FASP; 1990. Physicians’ Desk Reference, 52 ed. Montvale, N.J.:Medical Economics Co.; 1998. Physician’s Desk Reference Medical Dictionary. Baltimore:Williams & Wilkins; 1995.
  
  

• Male Response 45 tab

• Male REsponse 90ct





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Guggul – New Benefits for Heart Health


Date: May 11, 2005 09:00 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Guggul – New Benefits for Heart Health


Gum Guggul–New Benefits for Heart Health from an Age-Old Herb

by Richard Conant, L.Ac., C.N.

The 1990's have seen a growing interest in herbs from India's ancient Ayurvedic tradition. One Ayurvedic herb in particular, "gum guggul," stands at the forefront, thanks to its rather remarkable benefits for the heart and cardiovascular health. A relative of myrrh and frankincense, gum guggul is a resin tapped from India's Commiphora mukul tree. Known more commonly in the Far East as simply "guggul," the herb has proven to be one of the most effective natural cholesterol-lowering agents ever discovered. Cholesterol reductions with guggul can be twenty percent or higher, and the herb also raises HDL, the more beneficial form of cholesterol. Studies also show guggul may help prevent atherosclerosis, by retarding the formation of fatty, cholesterol-laden deposits in blood vessel tissues.

Recent research on guggul has revealed that guggul also blocks the oxidation of LDL cholesterol, by acting as an antioxidant. LDL, which carries cholesterol from the liver to the rest of the body, is generally regarded as a key element in the development of atherosclerosis. But only when it is oxidized by free radicals does LDL accumulate in arteries. It its unoxidized or "native" state, LDL is more or less benign. Checking LDL oxidation is vital to keeping blood vessels free of plaque.1 (This is one of the major reasons why antioxidants are so important.) Guggul, by both lowering blood cholesterol and acting against LDL oxidation, now stands out as one of the world's most valuable herbs for heart health.

Guggul first caught the attention of the scientific world in1966, thanks to an Indian medical researcher who submitted a doctoral thesis on gum guggul.2 Her interest had been kindled by references to the herb in a centuries-old Ayurvedic text. Apparently, poor cardiovascular health and atherosclerosis were a problem back then just as they are today. Translated from Sanskrit, this text describes, in elegant detail, a condition called "coating and obstruction of channels." The cause, according to the ancient writers? Faulty metabolism due to overeating of fatty foods and lack of exercise. Death was said to be the end result of leaving this condition uncorrected. The recommended treatment plan emphasized diet and herbs, chiefly gum guggul.3

References to guggul in ancient literature actually go back even farther. The herb is mentioned in the Vedas, the holy scriptures of India believed to be anywhere from 3,000 to 10,000 years old. One stanza is translated as follows: "Disease (consumption) does not afflict and the curse never affects whom the delicious odor of the healing Guggul penetrates (spreads). The diseases also flee away in all directions from him like horses and deer, O Gugulu! Either born from Sindhu or from the sea. I chant your name for the removal of diseases."3

Struck by the obvious similarity between "coating and obstruction of channels" and atherosclerosis, the Indian researcher decided to study gum guggul's effect on blood fats in rabbits. Over a two-year period, the animals were fed hydrogenated vegetable oil to artificially raise their cholesterol levels. Guggul was administered to one group of rabbits, while the rest served as controls. At the end of the study the rabbits given guggul had normal cholesterol and blood lipid levels. Their arteries showed no fatty streaks or plague deposits. This caught the attention of the Indian scientific community, and numerous clinical trials ensued, both on animals and humans. In study after study, guggul consistently produced substantial reductions in cholesterol and triglyceride levels, while Raising HDL.

The active ingredients in guggul are a group of natural plant sterols. Among these, substances called "guggulsterones" are the most important ingredients for the cholesterol and blood fat lowering properties of guggul, with the other sterols acting as a synergistic supporting cast.4 A number of mechanisms are suggested, although not definitely proven, for how the herb works; these include reducing the synthesis of cholesterol in the liver, enhancing cholesterol removal from the gut, stimulating thyroid function and increasing the number of receptors in the liver for uptake of LDL.3,5

Guggul extracts are now standardized for guggulsterone content. The herb naturally contains about 2 percent guggulsterones. Quality extracts contain a minimum of 2.5 percent, which assures the user is getting a product potent enough to produce results. Since the late 1980's clinical trials have used the standardized extract.6,7,8 The product is readily available in the U.S.

The ability of guggulsterones to prevent oxidation of LDL was discovered in a 1997 study done by scientists at the Central Drug Research Institute in Lucknow, India.9 This study sheds light on how guggul works against "coating and obstruction of channels." Remember that oxidized LDL forms the plaque that coats and eventually obstructs blood vessels. The researchers mixed LDL from human blood with a free radical promoting agent, either alone or in combination with guggulsterones. Samples were then analyzed for the presence LDL oxidation byproducts. The results showed that guggulsterones strongly protect LDL from being oxidized. Guggulsterones block the formation of hydroxyl radicals, a potent type of free-radical that attacks cell membranes.

Guggulsterones may also help keep the heart muscle itself healthy. When the heart muscle is deprived of oxygen, a condition known as "myocardial ischemia," it can be severely damaged by free radicals. The body tries to counter this with SOD, a key enzyme present in cells that neutralizes free radicals. SOD levels are significantly reduced in damaged heart tissues. Guggulsterones have been found to reverse this decrease by more than two-fold.10

Like the writer of that age-old verse found in the Vedas, contemporary herbalists hold gum guggul in the highest regard. Backed as it is by scientific research linked to centuries of traditional use, gum guggul has a bright future as a natural resource for maintaining normal cholesterol and blood fats, and for protecting heart health.

References

1. Heinecke, J.W. Free radical modification of low density lipoprotein: mechanisms and biological consequences. Free Radical Biology & Medicine 1987;3:65-73.

2. Satyavati, G.V. Effect of an indigenous drug on disorders of lipid metabolism with special reference to atherosclerosis and obesity (Medoroga) M.D. thesis (Doctor of Ayurvedic Medicine). Banaras Hindu University, varanasi, 1966.

3. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.

4. Dev, S. A modern look at an age-old Ayurvedic drug-guggulu. Science Age July 1987:13-18.

5. Singh, V. et. al. Stimulation of low density lipoprotein receptor activity in liver membrane of guggulsterone treated rats. Pharmacological Research 1990;22(1):37-44.

6. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.

7. Agarwal, R.C. et. al. Clinical trial of gugulipid-a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.

8. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.

9. Singh, K., Chandler, R. Kapoor, N.K. Guggulsterone, a potent hypolipidaemic, prevents oxidation of low density lipoprotein. Phytotherapy Research 1997;11:291-94.

10. Kaul, S. Kapoor, N.K. Reversal of chnages of lipid peroxide, xanthine oxidase and superoxide dismutase by cardio-protective drugs in isoproterenol induced myocardial necrosis in rats. Indian Journal of Experimental Biology 1989;27:625-627.

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Date: May 09, 2005 06:10 PM
Author: Darrell Miller (dm@vitanetonline.com)


It's in the Blood

Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

“The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

“Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

"Blur of Products"

With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while Raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

“The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

“Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

“The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while Raising levels of HDL cholesterol.

Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

“In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

New Weapons

There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

“Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/

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