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Unlocking the Benefits of Green Tea Extract Darrell Miller 8/10/23
Gymnema Sylvestre - An Herb That Promotes Healthy Glucose Metabolism Darrell Miller 10/25/22
Why you should never go gluten-free unless you have an actual allergy or disease Darrell Miller 7/15/17
What the Health: Watch the Whole Documentary Free On Youtube Darrell Miller 7/5/17
Sugar-Free Diet Plan, Benefits & Best Foods Darrell Miller 6/21/17
Is Gluten-Free Diet Necessary For People Wihtout Celiac Disease? Darrell Miller 5/18/17
Why You Shouldn't Go Gluten-Free Unless It's Absolutely Necessary Darrell Miller 5/5/17
How to grow pesticide-free organic celery Darrell Miller 4/4/17
Iodine-free salt create 'national health problem' Darrell Miller 3/31/17
Gluten-free diets: Where do we stand? Darrell Miller 3/4/17
Turmeric Believed to Be a Safer and Side-Effect-Free Pain Management Option for Arthritis Darrell Miller 2/2/17
The Conversation US: 13 ways to keep free radicals away, and why it's so important Darrell Miller 1/8/17
Even teethers labeled BPA-free may contain hormone-disruptors Darrell Miller 12/26/16
Dr. Rao of Diet Doc Warns That Going Gluten-Free Can Inadvertently Result in a Lack of Proper ... Darrell Miller 12/11/16
The Health Benefits OF Avocado Oil Darrell Miller 3/8/14
Acerola and its health benefits Darrell Miller 1/12/14
Can Melatonin Be Used For Fibromyalgia? Darrell Miller 12/28/12
Xanthan Gum Recipes Darrell Miller 12/18/12
Raspberry ketone for weight loss Darrell Miller 6/11/12
What Are The Health Benefits Of DMAE? Darrell Miller 4/26/12
Natural Vitamins for the Heart Darrell Miller 7/6/10
Fight Inflammation With Herbs from Planetary Herbals Darrell Miller 6/2/10
Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it Darrell Miller 2/25/10
Pine Bark Extract Darrell Miller 10/7/09
Ginkgo Biloba Darrell Miller 10/1/09
Schizandra Darrell Miller 8/4/09
Boost Absorption With Natural Vitamins Darrell Miller 4/17/09
Healthy Nails Darrell Miller 3/3/09
Mumps Darrell Miller 2/27/09
Re: Fight Mononucleosis By Boosting The Immune System With Herbs Darrell Miller 2/23/09
Alpha Lipoic Acid Darrell Miller 12/11/08
What is Alpha Lipoic Acid? Darrell Miller 7/18/08
Advocacy Update Darrell Miller 5/17/08
Papaya- May Be A Fountain of Youth Darrell Miller 5/31/07
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium Darrell Miller 5/18/07
Do you experience muscle pain and inflammation? Darrell Miller 4/25/07
Complete Liver Cleanse Darrell Miller 4/19/07
Regulating Blood Pressure Naturally Darrell Miller 3/28/07
l-Arginine/l-Citrulline Complex - Supports Peak Performance Darrell Miller 3/6/07
Neurological Health and CoQ10 Darrell Miller 2/25/07
Fruit and Vegetable Lightning drink mixes from Natures Plus Darrell Miller 2/6/07
What are Amino Acids? Darrell Miller 9/7/06
HDL Booster - Boost your good cholesterol Darrell Miller 3/16/06
High Absorption CoQ10 Darrell Miller 2/13/06
Benefits of Best Alpha Lipoic 35! Darrell Miller 2/12/06
Erythritol Sweetener Fact Sheet Darrell Miller 12/17/05
Tru-E Bio Complex Darrell Miller 12/8/05
Triphala Fact Sheet Darrell Miller 12/8/05
Vitaberry Plus + Super Fruit Antioxidant Darrell Miller 12/7/05
Life is more enjoyable when your stomach is prepared for it. Darrell Miller 11/28/05
Benefits of Alpha Lipoic Acid Darrell Miller 10/13/05
Benefits of Total Daily Formula Darrell Miller 10/13/05
Curcumin - Turmeric Extract Darrell Miller 8/19/05
WHAT EXACTLY IS PYCNOGENOL? Darrell Miller 7/13/05
Quercetin and Bromelain - for better health. Darrell Miller 7/4/05
Vision Quest - help fight eye problems. Darrell Miller 6/18/05
Green Power Darrell Miller 6/14/05
Home on the Range Darrell Miller 6/13/05
Basics of the Immune System Darrell Miller 6/10/05
Improove Memory ... Darrell Miller 6/9/05
AMINO ACIDS AND PROTEIN Darrell Miller 6/9/05
PYCNOGENOL ® - The Ultimate Antioxidant Darrell Miller 6/4/05
Muscle Mass - Reach Your Maximum Muscle Potential Darrell Miller 6/4/05
Glycerylphosphorylcholine Darrell Miller 5/24/05
Spectro 3 and Spectro Multivitamin Darrell Miller 5/21/05
LACTOSE INTOLERANCE AND ACIDOPHILUS ... Darrell Miller 5/18/05
related links Darrell Miller 5/18/05
Bee Propolis Darrell Miller 5/12/05
Guggul – New Benefits for Heart Health Darrell Miller 5/11/05



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Unlocking the Benefits of Green Tea Extract
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Date: August 10, 2023 10:43 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Unlocking the Benefits of Green Tea Extract

  • Powerful Antioxidant
  • Benefits of these antioxidants in fighting inflammation and chronic diseases
  • The role of bioactive compounds in green tea in improving immune function
  • Promotes Weight Loss
  • Improve Mental Efficiency
  • Green tea extract's impact on the central nervous system
  • How Natures Answer Green Tea Extract can enhance cognitive abilities
  • Promotes Heart Health

With the growing awareness about the health benefits of green tea, it comes as no surprise that it has become a popular health supplement. One potent green tea supplement that has continued to maintain attention is Natures Answer brand Green Tea Extract in an Alcohol-Free Liquid Extract. Packed with powerful antioxidants, this supplement can aid in digestion, weight management, and overall well-being.

Powerful Antioxidant

Antioxidants are substances that inhibit oxidation, a process that can lead to cellular damage. They act as scavengers, helping shield the body from harmful free radicals, which are unstable molecules that can inflict damage to our cells. This is where green tea, and particularly green tea extract, shines. Rich in antioxidants known as polyphenols, green tea plays a significant role in maintaining the body's overall health. Polyphenols, including flavonoids and catechins, are known for their potent antioxidant effects. The most notable catechin in green tea is Epigallocatechin Gallate (EGCG), widely studied for its powerful impact on health. Green tea's antioxidants help neutralize harmful free radicals, reducing oxidative stress, and subsequently lowering the risk of a host of chronic conditions including heart disease, type 2 diabetes, and even certain cancers. Thus, the antioxidants in green tea aren't just important, they're an integral part of a health-conscious lifestyle.

Boost Immune System

Green tea boosts immunity through its potent bioactive compounds, primarily polyphenols like catechins. These compounds exhibit powerful antioxidant properties, neutralizing harmful free radicals in the body. Additionally, they help increase the body's production of detoxifying enzymes, further enhancing the immune system's efficiency. Green tea also contains a type of catechin called Epigallocatechin Gallate (EGCG), renowned for its immune-boosting properties. EGCG aids in the production of T-cells, the body's first line of defense against infections. Furthermore, green tea fosters beneficial gut bacteria, which play a crucial role in maintaining a robust immune system.

Promotes Weight Loss

Green tea extract works to accelerate weight loss primarily through its active ingredients, one of which is caffeine. Although not as much as coffee, green tea does contain sufficient caffeine that can aid in fat burning and improving exercise performance. More importantly, it is loaded with potent antioxidants called catechins. The most important of these is Epigallocatechin gallate (EGCG), a substance that can boost metabolism. Studies suggest that the combination of EGCG and caffeine in green tea extract can assist in weight loss by helping the body burn more calories, even at rest, and breaking down more fat cells. Additionally, green tea extract is known to increase fat oxidation and improve insulin sensitivity, both beneficial for weight control. While the effects on each individual can vary, when combined with a balanced diet and regular exercise, green tea extract can indeed support and accelerate weight loss efforts.

Impacts Central Nervous System

Green tea extract is known to have profound effects on the central nervous system, primarily due to the presence of caffeine and an amino acid called L-theanine. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter in the brain called Adenosine. This increases the firing of neurons and the concentration of neurotransmitters like dopamine and norepinephrine, leading to improved brain function, mood, vigilance, reaction times, and even memory. On the other hand, L-theanine can cross the blood-brain barrier and has been shown to increase the activity of the inhibitory neurotransmitter GABA, which has anti-anxiety effects. It also increases dopamine and the production of alpha waves in the brain. The unique combination of these two compounds in green tea extract is believed to make it an excellent tool for maintaining and enhancing the central nervous system.

Improve Mental Efficiency

Green tea improves mental efficiency through several biological mechanisms. Primarily, it contains caffeine and L-theanine, two compounds known to enhance brain function. Caffeine, a known stimulant, works by blocking an inhibitory neurotransmitter called adenosine, which not only increases the firing of neurons but also amplifies the concentration of other neurotransmitters like dopamine and norepinephrine. This results in improved brain function, vigilance, reaction times, memory recall, and mood.

On the other hand, L-theanine is an amino acid that can cross the blood-brain barrier and has psychoactive properties. It promotes relaxation without drowsiness and can work synergistically with caffeine to enhance brain function. Furthermore, L-theanine increases the frequency of alpha waves in the brain, which leads to improved creativity and problem-solving abilities.

Moreover, green tea is rich in polyphenols and antioxidants, particularly Epigallocatechin Gallate (EGCG), which has protective effects on neurons, potentially lowering the risk of neurodegenerative disorders like Alzheimer's and Parkinson's disease. Hence, regular consumption of green tea or its extract can significantly improve mental efficiency.

Promotes Heart Health

Natures Answer Green Tea Extract Alcohol-Free Extract can help you maintain healthy cholesterol levels, reduce high blood pressure, and prevent blood clot formation that can lead to heart diseases. The polyphenol and catechin compounds in green tea extract are known to promote the health of the heart by reducing inflammation and improving blood vessels' function. Green tea maintains healthy cholesterol levels by inhibiting the absorption of cholesterol in the digestive tract and aiding in its excretion. This leads to a reduced level of LDL (bad cholesterol) in the bloodstream, while not affecting the levels of HDL (good cholesterol). Green tea extract can also lower blood pressure. The catechins it contains help to dilate blood vessels, improving their function and allowing blood to flow more easily. This can lead to a significant reduction in blood pressure, especially in cases of hypertension.

Furthermore, studies have shown that the antioxidants in green tea can prevent the oxidation of LDL cholesterol, a process that contributes to the formation of plaques in arteries and blood clot formation. By preventing this oxidation, green tea extract can reduce the risk of heart diseases and strokes.

Lastly, the anti-inflammatory nature of green tea's antioxidants helps in reducing inflammation in blood vessels, a condition that can contribute to heart disease. By reducing inflammation, blood flow improves, and the risk of heart disease decreases. In this way, green tea actively promotes heart health.

In conclusion, Natures Answer Green Tea Extract is an all-in-one supplement that can enhance your overall health and well-being in various ways. The antioxidant, anti-inflammatory, and weight management properties of this supplement can do wonders for your physical, neurological, and mental health. Incorporating Natures Answer green tea (alcohol free) liquid extract into your daily routine can help you unlock the multiple benefits that this tea has to offer. So, go ahead, give it a try, and reap the benefits of this powerful supplement!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6585)


Gymnema Sylvestre - An Herb That Promotes Healthy Glucose Metabolism
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Date: October 25, 2022 02:41 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gymnema Sylvestre - An Herb That Promotes Healthy Glucose Metabolism

Gymnema sylvestre is an herb that has been used traditionally in India for centuries. Modern research has shown that this herb may help to support healthy glucose metabolism through its ability to promote healthy pancreatic function.* In addition, gymnema exhibits potent Free-radical scavenging properties.* NOW® Gymnema Sylvestre Extract is standardized to gymnemic acids, which are the compounds that have been identified as its bioactive constituents.*

Gymnema sylvestre is a woody climbing shrub that grows in the tropical forests of central and southern India. The leaves of the plant have been used traditionally in Ayurvedic medicine for centuries.1 Modern science has validated many of the traditional uses for this herb and has identified several key active components.2-4

Promotes Healthy Pancreatic Function*

One of the traditional uses for Gymnema sylvestre was to support healthy glucose metabolism.5 This effect was thought to be due to the herb’s ability to promote healthy pancreatic function.* The primary active components in Gymnema sylvestre – gymnemic acids – have been shown in animal studies to increase insulin secretion from the pancreas.6,7 In addition, these compounds appear to help maintain healthy beta cell function and architecture.8,9 Maintenance of normal beta cell function is critical for long-term metabolic health since these cells are responsible for producing insulin in response to rising blood sugar levels.10,11

Exhibits Potent Free-Radical Scavenging Properties*

In addition to supporting healthy pancreatic function, recent research has shown that Gymnema sylvestre extracts also possess potent Free-radical scavenging properties.*12 These effects were attributed primarily to the gymnemic acids present in the herb.13 This natural Free-radical scavenging activity may help support cellular health.*

NOW® Gymnema Sylvestre Extract is standardized to a minimum of 25% gymnemic acids and provides 6:1 extract potency. For easy supplementation, take 2 capsules 1 or 2 times daily with food or water.

In Summary:

Gymnema sylvestre is an herb with a long history of use in Ayurvedic medicine. Modern science has validated many of the traditional uses for this herb and has identified several key active components, including gymnemic acids which have been shown in animal studies to increase insulin secretion from the pancreas. Additionally, extracts of Gymnema sylvestre have been shown to possess potent Free-radical scavenging properties which may help support cellular health.* NOW® Gymnema Sylvestre Extract is standardized to a minimum of 25% gymnemic acids and provides 6:1 extract potency. For easy supplementation, take 2 capsules 1 or 2 times daily with food or water.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6523)


Why you should never go gluten-free unless you have an actual allergy or disease
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Date: July 15, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why you should never go gluten-free unless you have an actual allergy or disease





People who go gluten-free may feel better because, to avoid the protein, they end up cutting out desserts and junk foods, thus losing weight. You can eat a healthy diet without gluten, but you have to be very knowledgeable. Symptoms of gluten sensitivity are very similar to those of celiac disease and wheat allergy, often including digestive issues, emotional concerns, and joint and muscle pain. people on a gluten-free diet are more likely to increase their intake of essential nutrients, especially if they replace breads and other flour products with whole foods.

Key Takeaways:

  • The complex carbohydrates provided by wheat and grain are an essential part of your diet that shouldn't be ignored.
  • The benefits from eating gluten can't be substituted in pill form. Problems will persist.
  • "Gluten free" has come to incorrectly be synonymous with "Healthy", which is not true.

"When you're on a gluten-free diet, your body is at high-risk for inflammation, which the doctor says can slow your metabolism down and actually make you gain weight."

Read more: http://www.thisisinsider.com/why-you-should-avoid-a-gluten-free-diet-2017-6

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4975)


What the Health: Watch the Whole Documentary Free On Youtube
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Date: July 05, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What the Health: Watch the Whole Documentary Free On Youtube





What the Health, a documentary about health, is available on YouTube. There are millions of people around the world that have diabetes. We are in the middle of a large epidemic and diet is the biggest contributing factor to that. There are so many foods out there that are bad for you. Bacon, for example, can cause cancer and is very bad for you. If you have deli meats everyday, then you are at risk. Smoking is not the only danger out there.

[video mp4="https://www.healthnutnews.com/what-the-health-watch-the-whole-documentary-Free-on-youtube/"]

Key Takeaways:

  • Dr. Robert Ratner suggests we are in the midst of a diabetic emergency, as there are approximately 350 million sufferers of the disease right now, worldwide.
  • Research pulled from hundreds of countries shows a direct link between processed meat and cancer.
  • The World Health organization takes the link seriously, considering the danger as equal to that of smoking, or being exposed to asbestos.

"From Salmonella and other things you eat, we have about 3,000 people die every year, in the United States, that's more than the number of people that were killed in 9/11 in the Twin Towers of New York."

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4927)


Sugar-Free Diet Plan, Benefits & Best Foods
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Date: June 21, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Sugar-Free Diet Plan, Benefits & Best Foods





The authors message in the article is to stress how important it is to cut out some of the sugars from our daily lives, and replace them with more substantial foods. He lists examples such as complex carbs and proteins as well as high fiber foods. The author also gives us a list of foods that are high in protein and fiber as well as sugar-free. On top of this he also includes things such as healthy fats and probiotics to aid digestion.

Key Takeaways:

  • Many people are trying to reduce sugar in their diets. It's important to do this properly and not merely replace the sugar with empty calories.
  • Reducing sugar in your diet can prevent or reverse damage from diseases such as Type II Diabetes, fatty liver, Crohn's, etc.
  • For a low-sugar diet, avoid added sweeteners, refined flour, processed food, cane sugar. Replace the calories with fiber, protein and healthy fats.

"Another perk is that most low-sugar or sugar-free diets don’t require calorie counting, since eliminating processed foods is usually enough to produce results on its own."

Read more: https://draxe.com/sugar-free-diet/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4861)


Is Gluten-Free Diet Necessary For People Wihtout Celiac Disease?
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Date: May 18, 2017 10:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is Gluten-Free Diet Necessary For People Wihtout Celiac Disease?





An estimated three million Americans suffer from Celiac disease, an autoimmune disorder. Many people with celiac disease have stopped consuming foods with gluten in them, however many people without the disorder have also taken up gluten-free diets. Cutting out gluten also means cutting out many nutritional whole grain foods. People with and without celiac disease who choose to cut gluten out of their diets need to be aware that they may be missing vital nutrients.

Read more: Is Gluten-Free Diet Necessary For People Wihtout Celiac Disease?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4639)


Why You Shouldn't Go Gluten-Free Unless It's Absolutely Necessary
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Date: May 05, 2017 06:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why You Shouldn't Go Gluten-Free Unless It's Absolutely Necessary





There are people who have to eat a gluten free diet due to health problems. Some can't process gluten in their bodies so eating it makes them sick. They should definitely avoid gluten. Others do so but it's not for medical reasons, it's just something they feel will be better for them. They are wrong about it. Gluten free diets should not be adopted unless you have to. This explains this and why it is.

Read more: Why You Shouldn't Go Gluten-Free Unless It's Absolutely Necessary

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4543)


How to grow pesticide-free organic celery
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Date: April 04, 2017 06:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to grow pesticide-free organic celery





Celery is one of the most consumed vegetables but can contain high levels of chemicals from pesticides. It is also a difficult vegetable to grow and demands constant care and watering. Celery takes a long time from planting to harvesting. The soil has to be right as does the amount of sun versus shade. It can be grown organically with the use of other plants as natural barriers, mulch and organic pesticides to guard against bugs and disease.

Read more: How to grow pesticide-free organic celery

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4350)


Iodine-free salt create 'national health problem'
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Date: March 31, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Iodine-free salt create 'national health problem'





Studies show that iodine deficiency is has lead to a number of complications in Israel, including harm to pregnant women. Such complications impede the successful development of children after birth as well. The culprit has been identified as de-iodized salt. Consequently, policy makers and researchers are sounding the alarm so that the problem is corrected. According to them, the health of the nation is at stake. Moreover, according to experts, consuming certain foods would help to alleviate the problem as well as purchasing iodized salt. The problem is that it is difficult to acquire and is only offered at a premium price.

Read more: Iodine-free salt create 'national health problem'

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4327)


Gluten-free diets: Where do we stand?
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Date: March 04, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gluten-free diets: Where do we stand?





Gluten free diets have gained a lot of popularity over the years. People have eliminated gluten from their diets, even if their doctors have said not to do so. The gluten free craze is something that has gained a lot of momentum over the entire world. It is the most popular diet in Hollywood. There is little research in the area.

Key Takeaways:

  • r people with celiac disease, the gluten-free diet is like insulin for diabetics
  • There's nothing specifically bad about gluten or specifically good about a gluten-free diet, outside of for these specific -- not uncommon but relatively small -- populations of people with celiac disease, which is about 1% of people in the general population
  • celiac disease is an autoimmune disorder, spurring the immune system to attack its own intestines when gluten enters the body

"Over the past few decades, millions of people around the world have distanced themselves from gluten, eliminating gluten sources from their diets."



Reference:

//www.cnn.com/2017/03/01/health/gluten-Free-diet-history-explainer/index.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4071)


Turmeric Believed to Be a Safer and Side-Effect-Free Pain Management Option for Arthritis
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Date: February 02, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Turmeric Believed to Be a Safer and Side-Effect-Free Pain Management Option for Arthritis





Arthritis is a painful and terrible disease. NSAIDs are taken in handfuls for this condition, but have their own side effects. If you suffer from this disease, you may want to look into more natural ways of treating the inflammation. Turmeric is one such natural option that can greatly ease the pain involved. Some studies have been conducted to test the effectiveness of turmeric against NSAIDs. While they both seem to be close to equally effective, turmeric does not come with any side effects.

Key Takeaways:

  • Traditionally, many people who suffer from painful conditions such as arthritis non-steroidal anti-inflammatory drugs (NSAIDs).
  • Yet the recent scare in the possible side effects associated with their use has become widespread, and more and more sufferers are turning to natural alternatives.
  • Read on to learn more about turmeric and other safe, effective natural alternatives.

"Turmeric is believed to be a safer, side-effect-free pain management option for arthritis."



Reference:

https://www.google.com/url?rct=j&sa=t&url=https://newswire.net/newsroom/pr/00094817-turmeric-believed-to-be-a-safer-and-side-effect-Free-pain-management-option-for-arthritis.html&ct=ga&cd=CAIyGmZmMDFkMTU2YWMzMmQ5OTU6Y29tOmVuOlVT&usg=AFQjCNGNztCXwda6fyFk-o716SAJqqkKiQ

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3870)


The Conversation US: 13 ways to keep free radicals away, and why it's so important
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Date: January 08, 2017 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Conversation US: 13 ways to keep free radicals away, and why it's so important





Free radicals are molecules that are missing one or more electrons. They can damage your cells, which has been linked to health problems from wrinkles to cancer. Eating a diet rich in anti-oxidants fights the proliferation of free radicals, but the holidays, with their rich array of fatty, starchy, and sweet dishes, can make it more difficult to get those healthy anti-oxidants -- in the form of fresh fruits and veggies -- into your diet. But with a little diligence and pre-planning, you can have a healthy and delicious holiday season.

Key Takeaways:

  • raditional holiday meals are laden with salt, fat and sugar, which can spike blood glucose and insulin levels when eaten in excess all in one day. They also, alas, can increase the amount of free radicals, or molecules with unattached electrons, in the body, which can do serious cellular damage.
  • If a substance is “oxidized,” it has lost electrons to another substance. In contrast, we say a substance is “reduced” when it has gained electrons from another substance.
  • Our mitochondria, which operate like little factories in our cells, are responsible for burning fuel from food and producing energy in each of our cells via a process called oxidative phosphorylation.

"The oxidizing agents that have accepted electrons become free radicals if the unpaired electrons don’t bind to other molecules. These free radicals mess with our cellular metabolism, even interfering with our DNA."



Reference:

//www.huffingtonpost.com/the-conversation-us/13-ways-to-keep-Free-radi_b_13870866.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3757)


Even teethers labeled BPA-free may contain hormone-disruptors
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Date: December 26, 2016 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Even teethers labeled BPA-free may contain hormone-disruptors





A recent report in the journal Environmental Science and Technology states that 59 different teething devices they tested all came up positive for BPA, which is a known endocrine-disrupting chemical. They also found other dangerous chemicals present in some, but this is one of the most concerning. These chemicals disrupt normal hormone function and can cause abnormal growth and development in children. The real problem is that all of the products were marked as BPA-free. Obviously, stronger measures need to be put in place to make sure companies are properly advertising their products.

Key Takeaways:

  • Some baby teething toys marketed as non-toxic might contain chemicals that could interfere with hormones involved in normal growth and development, a study suggests.
  • All of the products tested positive for one such chemical, bisphenol-A (BPA), even though most of the teethers were marketed as BPA-free, researchers report in the journal Environmental Science and Technology.
  • In animal studies, endocrine-disrupting compounds such as BPA, parabens and antimicrobials have been shown to interfere with hormones and have harmful developmental, reproductive and neurological effects.

"In lab tests for the current study, researchers found BPA as well as a range of different parabens and the antimicrobials triclosan and triclocarban in most of the teethers."



Reference:

https://www.yahoo.com/news/even-teethers-labeled-bpa-Free-may-contain-hormone-193030007.html?ref=gs

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3704)


Dr. Rao of Diet Doc Warns That Going Gluten-Free Can Inadvertently Result in a Lack of Proper ...
TopPreviousNext

Date: December 11, 2016 04:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Dr. Rao of Diet Doc Warns That Going Gluten-Free Can Inadvertently Result in a Lack of Proper ...





With the emergence of Celiac disease in recent years, there are many who have cut gluten from their diet even though they do not suffer from the condition. It has been viewed as a fad new diet, but specialists argue that it can negatively impact your diet. The concern is that the lack of fortified breads, pastas, and cereals in a diet will cause a deficiency in essential B vitamins, folate, and fiber that come from them. Doctors are advising those who do not have Celiac disease to not cut gluten from their diet.

Key Takeaways:

  • A new report by Harvard Medical School states that gluten-free dieting can easily result in a lack of proper nutrition, particularly for those without celiac disease.
  • The truth is that there are no published reports showing that a gluten-free diet produces weight loss in persons without celiac disease or gluten sensitivity.
  • Researchers are concerned that consumers who are eager to drop gluten from their diets may be lacking the essential B Vitamins, folate and fiber that comes from consuming fortified breads, cereals and pastas.

"This truth is that there are no published reports showing that a gluten-free diet produces weight loss in persons without celiac disease or gluten sensitivity"



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.marketwired.com/press-release/dr-rao-diet-doc-warns-that-going-gluten-Free-can-inadvertently-result-lack-proper-nutrition-2180287.htm&ct=ga&cd=CAIyGmZjNGVlYTM1NDU3YmZmOGU6Y29tOmVuOlVT&usg=AFQjCNGOODeko9G9f8TBQi9HahvO4AlLWg

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The Health Benefits OF Avocado Oil
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Date: March 08, 2014 09:02 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Health Benefits OF Avocado Oil

avocado fruitBenefits of avocado

Avocado oil has a high attention of healthier fats and supplement E, that is a fabulous epidermis lotion. Icy pressed virgin avocado oil, taken consistently, may help decrease levels of cholesterol and ensure against coronary illness.

Clearspring regular Avocado oil is icy pressed from oil-rich green olives and is broadly distinguished for its wellness profits notwithstanding a support to excellence.

Foul avcado oil is recognized to be a standout amongst the most restorative vegetable oils one can consume. It is a multi-reason oil that could be utilized for culinary purposes suitable for dressings and sauces and singing, because of its high smoke purpose of over 490 degrees. Natural avocado oil is additionally a top notch "transporter" oil for different qualities; avocado bearer oil is perfect for implantation with different herbs. Notwithstanding its suitability as an edible, foul avcado oil is additionally top notch for utilization as a corrective and the repair of harmed skin.avocado bearer oil is fine for making diverse seasoned oils. Despite the fact that fine for people and different primates, natural avocado oil holds a fattening corrosive known as persin, which might be profoundly poisonous to local creatures, especially pooches, felines and stallions.

This offers no issues to your general health or that of your skin, and holds a monounsaturated oil utilized within fragrance based treatment. There is nothing else in avocado oil with the exception of the 30% of oil that the foods grown from the ground holds. You can drink it without it doing you hurt. An engineered proportionate to avocado oil might fill the mark with included chemicals: one or more to enhance skin ingestion, some to protect the oil from oxidation (despite the fact that it holds its own particular cancer prevention agents), emulsifiers and surfactants to help it spread better (an oil?).

Avocado content

Actually avocado oil holds its own particular emulsifier, lecithin, and additionally the cancer prevention agents Vitamin An and Vitamin E that likewise help to administer a young looking skin. These cell reinforcement vitamins annihilate the free radicals that execute your skin cells and make you look more advanced in years. Avocado oil can help you to continue looking more youthful as you develop sequentially more senior. It likewise holds vitamin D that is so paramount in large portions of the natural methodologies inside your skin - it is not called the 'daylight vitamin' to no end.

Cell reinforcements secure you from the impacts of the less than great UV radiation held in solid daylight, the Free-radical producing pesticides, activity and modern outflows and tobacco smoke. Without some type of cell reinforcement medicine your skin would quickly wrinkled and develop old as its unit films are burst and annihilated. Vitamins An and E execute off the free radicals that cause this.

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Acerola and its health benefits
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Date: January 12, 2014 01:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acerola and its health benefits

Vitamin CAcerola:

Acerola cherries, also known as Malpighia emarginata is a small fruit bearing shrub native to central and southern America and West Indies. It is also grown in California and subtropical areas of Asia that is India and is an important source of nutrient for the people living in this area for over hundreds of years. It came into use in 1950 when some of the manufactures found that orange juices are too acidic for infants and could prove to be harmful for them. Acerola is rich in Vitamin C. A Mild portion of Acerola extract in orange juice would be less acidic and full of Vitamin C.

Health benefits:

According to a scientific study done on mice suffering from lung tumours, Acerola helps in regulating the abnormal cell growth. According to researchers, the Anthocyanins present in the fruit are mainly responsible for the action.Therefore, various surveys and studies around the globe it has been found that antioxidants in acerola have disease-fighting agents and thus play a key role in preventing and managing health problems such as cancer, hypertension, bacterial infections, and diabetes. It has Free-radicals and anti-fungal agents that prevents skin aging and helps in fighting cancer. Due to the high concentration of vitamin C and unique combination of antioxidants in it, acerola has proven to be an important health supplement. The vitamin C in it has much more anti oxidative power and is readily absorbed due to the presence of ingredients like vitamin A, niacin, vitamin B2, vitamin B1, calcium, phosphorus, protein, and iron. They can be taken in the form of powder, tables, capsules, syrups, or juices and only moderate consumption of Acerola cherries are recommended as over-dosage could cause diarrhea.

Acerola is thus an amazing source of vitamin C. This is a water soluble vitamin and thus it leaves the human body quickly. This is the reason for the necessity of the regular consumption for the optimum health. In order to function properly, every gland and organ in human body needs the vitamin that plays a role in fighting infection and healing body.

References:

  1.  //en.wikipedia.org/wiki/Malpighia_emarginata
  2.  //www.livinghealthy360.com/index.php/nutritional-benefits-of-acerola-cherries-8-35753/

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Can Melatonin Be Used For Fibromyalgia?
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Date: December 28, 2012 04:19 PM
Author: Darrell Miller (dm@vitanet.net)
Subject: Can Melatonin Be Used For Fibromyalgia?

Fibromyalgia is a condition that may be very frustrating and has no known cure currently. Due to its complexity and also the number of symptoms that occur during an infection with fibromyalgia, one may be moody, anxious, depressed or irritable. Melatonin, a natural hormone which controls sleep patterns, can help relieve some symptoms of fibromyalgia and promote one's feelings of well-being.

About Melatonin

Melatonin hormone is produced by the brain's pineal gland. It is majorly responsible for controlling the sleep-wake cycle; called the circadian rhythm. The secretion of melatonin is influenced by exposure to light. Whenever it gets dark, melatonin production rises. Conversely, during exposure to sunlight, the production of melatonin is lowered. Several people employ the use of melatonin supplements to promote symptoms of insomnia, since it can aid to reset one's body clock and even make it easier to fall and stay asleep.

How melanin treats Fibromyalgia

Disturbances of sleep and the frequent disruption of circadian rhythms occur during fibromyalgia. Melatonin has always been proven to synchronize the circadian rhythms and promote the quality of sleep. Excess damage by Free-radicals is quite common in fibromyalgia patients. Melatonin as well as its metabolites have been discovered to be potent scavengers of free radicals and indirect antioxidants.

Elevated Nitric Oxide In Patients

Some studies have shown that synthesis of nitric oxide is elevated in fibromyalgia patients. Melatonin acts as a potent inhibitor of a rate-limiting enzyme in the production of nitric oxide. Depression is at times a symptom or maybe an overlapping fibromyalgia condition.

Melatonin As An Antidepressant:

Melatonin has also been proven to be an antidepressant. There is a component of melatonin that has been synthesized in the pharmaceutical industry and is now being enhanced as an antidepressant. Lyrica, antiepileptic drugs, have been proven to be effective in the treatment of fibromyalgia. Melatonin has been found to work as an antiepileptic too.

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Xanthan Gum Recipes
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Date: December 18, 2012 11:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Xanthan Gum Recipes

Natural Healthy Thickener

Anyone who has wielded a ladle knows exactly what it means to get the right consistency in sauces and soups. Generally a flour, either cornstarch or arrowroot powder based additive, which is carbohydrate rich, make our soups and sauces thick, using conventional cooking methods. However, with growing concerns over carb -rich diets being linked to obesity and the recurring need for thickening required in cooking, has necessitated a switch without compromising on health.

Synthetic thickeners are not recommended though sometimes used commercially . Xanthun gum is a naturally derived form of a thickener made through the fermentation of glucose or sucrose using the harmless bacteria Xanthomonas campestris. Marketed from the 1960's, this harmless bacteria forms one of the most useful thickening agents that has been used commercially in the food industry. It has been used as an anti-settling agent, thickener and emulsifier for ice creams, smoothies, gums and confectioneries and even as a binding agent in creams ,lotions as well as other cosmetics including lipsticks.

Xanthan Gum Powder-Here are some benefits that one could look forward to:

  • * Go gluten Free-Reduce your fear of gluten by substituting flour with xanthan gum in breads, cakes and pasta. Those who suffer from gluten allergy may use this natural substitute in their diet in place of flour.
  • *Provides all your dairy based products with a creamy texture, it does not deprive you of the pleasure of a dessert .
  • * Acts as a perfect binding agent in gluten- free and even egg -free cooking.
  • *It does not alter the color or flavor of the food.
  • *Xanthan gum is known to have skin hydrating properties and thus manages to find its way into some of the most popular and commonly sold cosmetics. Being hypoallergenic and non acidic, one could find it in liquid soaps, lotions, creams, shower gels, and shampoos.
  • * Because of its ability to coagulate and form a gel, it works wonderfully in the human digestive system to cleanse the colon with absolutely no harmful effects if taken within a certain limit. All therapeutic usage however requires the careful instructions of a therapist.
  • *Rich in fiber-Every teaspoon of xanthan gum powder has 7 grams of fiber which also explains its digestive cleansing action that in some cases may cause bloating.

This polysaccharide needs to be used in small quantities thus it is not only affordable but can get easily amalgamated into home cooked food recipes with absolute ease ending up providing the most mouth watering of recipes the respite from censure .

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Raspberry ketone for weight loss
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Date: June 11, 2012 08:21 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Raspberry ketone for weight loss

Raspberry ketones

Raspberry ketones are natural compounds that are found in raspberry plants and that are able to regulate metabolism in the same manner as synephrine and capsaicin since they are chemically similar. Ketones are also responsible for the pleasant smell of raspberries and they are also used as a flavoring ingredient for processed food. Various studies have shown that these ketones are also extremely potent fat burners and this is the main reason why they are highly marketed as being an effective solution for weight loss.

It was scientifically proven that people who choose to live a healthy lifestyle and who also watch their weight can have a significant benefit from using raspberry ketone supplements. Most people can lose a considerable amount of weight by using these supplements and it works with any type of diet. It also works extremely well and burns fat even more effective when it is combined with a high protein diet that is low on fat. This is basically one of the main reasons why this supplement is so high in demand nowadays.

Weight Loss

Whenever raspberry ketone is used as a supplement the core temperature of the body is significantly raised. Therefore the metabolism rate will also be increased and it will cause the body to burn fat and calories much faster, making this compound very popular and effective when it comes to weight loss. In addition, these ketones will also make the overall fat that the body is absorbing from a regular diet to be reduced. In fact, a study conducted on rats in Japan reveals that this compound is extremely effective in fat loss after it prevented fat from accumulating in their tissues. This is a strong evidence that proves how effective for boosting metabolism and burning fat this supplement really is. Although no study was documented on humans, there are various positive feedbacks from users that prove to be effective and free of any side effects as well.

Due to the raspberry ketone effectiveness, most nutritionists and dietitians are also recommending to eat a few raspberries along with meals. People who went for a healthy diet and also consumed raspberries on a regular basis have experienced positive weight loss results. This fruit is also very delicious and is rich in fiber so it is a good addition to any meal. Raspberry ketones are also known for several other health benefits such as maintain the level of fat and cholesterol in the body. Also, by consuming this compound you can also maintain your blood pressure levels in normal range, therefore these ketones are also good for maintaining the overall health for the cardiovascular system.

So basically all these healthy and beneficial properties make raspberries a very healthy fruit. They also contain anti-oxidants which are most needed for combating the harmful Free-radicals present in the body. Since it would take many pounds of actual raspberries in order to get any significant results, supplements based on this compound are the perfect choice in order to get the recommended dosage (usually around 100-300mg).

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What Are The Health Benefits Of DMAE?
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Date: April 26, 2012 12:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Health Benefits Of DMAE?

DMAE

Dimethylaminoethanol or DMAE is anorganic compound that is metabolically produced by the adrenal glands, testes and the brain in small quantities. It is converted into testosterone, estrogen and cortisone by the body. It is a known fact that the liver processes DMAE into choline, but the molecule thus produced is charged and cannot break the blood-brain barrier. Studies have shown that DMAE methylated in the brain acts as the precursor for the manufacture of acetylcholine, a neurotransmitter that plays a key role in the conduction of signals in the brain as well as the nervous system.

DMAE also stimulates phosphatidylcholine, a crucial part of cell membranes. However, the DMAE naturally produced by the body is sufficient only to maintain healthy brain and functions. It will not improve their functions. Though DMAE is found in fish such as salmon, anchovies, and sardines, supplementation in the pill form is important because of the practical difficulties having these foods in the right form and quantity on a daily basis to derive the benefits. DMAE supplements for oral consumption are through stores that sell health foods and groceries.

Daily consumption of DMAE in the supplement form provides a number of benefits to the body. Some of the benefits are as follows:

It helps prevent as well as treat cardiovascular problems and boost the body's immune system because of its strong antioxidant properties.It protects cells from the harmful effects of Free-radicals by helping them retain the nutrients that are essential and expelling waste.As a precursor in the production of the neurotransmitter acetylcholine, it supports the functioning of the brain in a number of ways. It increases a person's attention span, relieves behavioral problems and hyperactivity or attention deficit hyperactivity disorder. It is also helpful in treating memory lapses and Alzheimer's disease.

It helps stop production of arachidonic acid which is responsible for wrinkling and aging of skin. Topical creams containing DMAE help tighten skin and reduce wrinkles and fine lines.It is found to be effective in burning fat because of its involvement in the production of acetylcholine. It increases the metabolism in the body because of its thermogenic effect.It can be beneficial as an anti-inflammatory as well.It can reduce the amount of sleep required for a person by up to one hour.It can safely be used as a substitute for anabolic steroids.

research

Research studies have shown that consumption of 200 to 500 mg of DMAE on a daily basis is helpful in improving health. However, it is important to start with a low dosage of DMAE and then gradually increase the dosage level to the optimum level. Higher dosage can cause headaches, insomnia and muscle tension. People suffering from conditions such as schizophrenia, mental depression and epilepsy should not have DMAE supplements. Pregnant and lactating women also should not have DMAE.

Summarizing, consumption of recommended amounts of DMAE is believed to be safe. Side effects due to consumption of DMAE are rare and not generally serious. However, it is important to use high-quality supplements in order to increase DMAE levels in the body and reap the benefits.

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Natural Vitamins for the Heart
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Date: July 06, 2010 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins for the Heart

It has been consistently revealed by epidemiological research that individuals with a high dietary intake of antioxidant vitamins have a risk that is lower-than-average of cardiovascular disease. This evidence seems to be especially consistent for vitamin E. Additionally, many clinical studies show that magnesium supplementation is of significant benefit in the treatment of cardiac arrhythmias and in reversing the depletion of potassium that comes along with a magnesium deficit. Many cardiovascular events like angina pectoris, congestive heart failure, and cardiomyopathy are related directly to low magnesium status. Coenzyme Q10 is an essential component in cellular energy production. This nutrient is also prevalent in the heart muscle. When tissue levels of CoQ10 are low, there is an association with several cardiovascular complications. Among these are angina, congestive heart failure, cardiomyopathy, hypertension, and mitral valve prolapse. Research has found that the trio of coenzyme Q10, vitamin E, and magnesium plays a crucial role in the maintenance of cardiac health and the prevention of disease states.

The cardio-protective effect of vitamin E seems to come from its ability to bind to LDL cholesterol, which protects it from Free-radical induce oxidative damage along with the consequent buildup of atherogenic plaque. Low levels of vitamin E in the blood are a predictive factor of heart health almost 70% of the time.

Studies on the general population have suggested that there is a link between the intake of calcium and blood pressure. Although results of the studies have not been consistent, there are several studies showing that calcium supplementation can lower blood pressure in those individuals who experience hypertension. Overall, those intakes of calcium that are sub-optimal contribute directly to hypertension. It seems that dietary calcium reduces blood pressure by normalizing intracellular calcium levels.

Supplementation with magnesium is of benefit for the treatment of cardiac arrhythmias and the prevention of potassium depletion. Both magnesium and potassium play an important role in the functioning of the heart. Several studies have found that there is improvement in heart function in those patients that have cardiomyopathies when they supplement with magnesium. Since magnesium acts in so many ways to enhance cardiac function and optimize cellular metabolism, magnesium is widely recognized as a critical nutrient for general cardiac support.

Several double-blind studies have taken place in those patients that experience various cardiomyopathies in order to show the benefits of CoQ10 supplementation. One study reported an 89% improvement rate in 80 cardiomyopathy patients who were treated with CoQ10. The coenzyme also appears to moderate blood pressure through the usual mechanism, as it lowers cholesterol levels and also stabilizes the vascular system with its antioxidant properties. Because of this, it is able to reduce vascular resistance. Several studies on CoQ10 supplementation have confirmed that this nutrient posses the ability lower both systolic and diastolic pressures by up to ten percent.

There are other nutrients that play important roles in optimizing cardiovascular health and reducing hypertension. Among these nutrients are gamma tocopherol, calcium, magnesium, l-carnitine, acetyl-l-carnitine, procyanidolic oligomers, phenolic compounds, and lycopene. As you can see there are many natural supplements that can help the cardiovascular system. Remember to always consult your doctor before adding supplements to your diet while on prescription drugs. Look to your local or internet health food store for quality vitamins, herbs, and specialty formulas to boost your health and wellness.

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Fight Inflammation With Herbs from Planetary Herbals
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Date: June 02, 2010 04:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Inflammation With Herbs from Planetary Herbals

Inflama-Care 60 tabs from PLANETARY HERBALSOur modern lives have untold benefits, as well as challenges. Our dependence on man-made toxic chemicals, junk food, nutrient imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health.

These lifestyles and environmental change can challenge immune health, so that the various components of the immune system are not able to carry out their protective functions. Or our immune systems can go into overdrive, often leading to a state called metabolic inflammation.

A Powerful Herbal Blend

Inflamma-Care is a potent, herbal response to the metabolic inflammation that can result from inappropriate immune response. The main component of inflama-care is the rhizome of the curcuma spicies, long used as a spice in India. Known worldwide as turmeric (curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines – inflammation messengers.

This world-renowned spice is supported by boswellia, which inhibits pro-inflammatory enzymes, and ginger an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skullcap, corydalis, holy basil, and hops.

Inflama-care also contains systemic enzymes to clear and protect the arteries and circulatory system. Systemic enzymes like bromelain and papain cleanse the bloodstream and enable the blood to flow smoothly. A Free-flowing bloodstream helps the body by circulating important nutrients to the cells while clearing the body of wastes.

Immune Activating Mushroom

Planetary Herbals also offers you new Full Spectrum Chaga in 1000mg tablets and a 1:4 liquid extract. Preliminary studies suggest that chaga triggers immune responses and protects the cells with antioxidant activity.

Chaga is a mushroom that is found attached to trees like birch, alder, beach, and other hardwoods, throughout the northern Chaga Full Spectrum 60 tabs from PLANETARY HERBALSlatitudes. A polyphore, the mushroom looks somewhat like coal – a brownish black mass often seen in tree trunks. In China, Siberia, Finland, Japan, Poland and North America, ancient and native peoples have long known the benefits of chaga. In an acient treaties, the Chinese monk shen nog declared in 100 BC that chaga is “a precious gift of nature.”

In modern research, chaga has been shown to have 215 phytonutrients, including 29 beta-glucans. Chaga also absorbs a nutrient from the outer birch tree bark: betulin, a natural anti-inflammatory. Among the components in chaga are triterpenes, sterols, beta-glucans, flavonoids, melanins, polyphenols, saponins, lignin, amino acids, vitamins, minerals, and fiber. This fascinating combination of nutrients is being studied worldwide.

The PhytoDynamic Difference

Both inflama-care and full spectrum chaga are formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. The result: herbal products unsurpassed for quality and consumer satisfaction.

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Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it
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Date: February 25, 2010 09:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamins and Herbs to Fight Sunburns, and Sunblock to Prevent it

Aloe Vera Sunblock SPF30 LILY OF THE DESERTSunburn is the result of excessive exposure to the sun’s ultraviolet (UV) rays. The amount of exposure that is required to cause a burn is unique to each individual, the geographical location, the time, and the atmospheric conditions. There are two types of ultraviolet rays, which are designated as ultraviolet-A (UVA) and ultraviolet-B (UVB). Both types of ultraviolet rays are dangerous. UVB rays attack the skin’s outer layers, while UVA rays attack the underlying layers of the skin.

The majority of sunburns are first-degree burns that cause the skin to become red, warm, and tender to the touch. Depending on the severity of the burn and the individual’s skin type, the burn may subsequently “cool” into a suntan or thin layers of skin may peel off. More serious sunburn can be categorized as a second-degree burn. A second-degree burn consists of extreme reddening, swelling, pain, and even blisters. This is a sign that the burn has gone deeper than just the surface layer of the skin and has caused damage and the release of fluids from cells in the lower layers of the skin. The result of this is eruptions and breaks in the skin where bacteria and other infectious organisms can enter. In the most severe cases, a burn can be accompanied by chills, fever, nausea, and/or delirium. These types of sunburns are extremely painful and are extremely dangerous for children. Sunburn can often be accompanied by dehydration.

Those people who are fair-skinned are more prone to sunburn than those darker-skinned individuals. However, no matter what your skin color, you will burn if you get enough exposure. Symptoms do not always appear while you are in the sun, as they may begin from one hour to twenty-four hours after sun exposure and they usually reach their peak in two to three days. Natural Mineral Oil Free Sunblock SPF18 4 fl oz from ALBA BOTANICA

The effects of sun exposure are becoming an increasing concern today due to the decline in the earth’s ozone layer. The ozone layer is responsible for screening out the most harmful ultraviolet rays, but it is becoming increasingly thinner all over the world. Holes that fluctuate in size have even developed in various places. Additionally, the incidence of skin cancer is growing at an alarming rate. It has been found that having two or more bad episodes of sunburn as a child can make you much more likely to develop skin cancer as an adult.

The following nutrients are recommended for prevention and treatment of sunburn: coenzyme Q10, colloidal silver, DMB, a Free-form amino acid complex, L-cysteine, a multivitamin and mineral complex, potassium, Pycnogenol, vitamin A with mixed carotenoids, vitamin C with bioflavonoids, an all-purpose bactericide spray, calcium, magnesium, essential fatty acids, silica, a vitamin B complex, vitamin E oil, and zinc.

Additionally, the following herbs may be beneficial in treating sunburn. Aloe vera gel has been noted to be remarkably effective in treating any kind of burn. It is responsible for relieving discomfort, speeding healing, and also helping to moisturize the skin and relieve dryness. A salve of calendula flowers and St. John’s wort can act as painkiller for burns and promote healing of skin wounds because these herbs have antiseptic properties.

Also, Lavender oil or chamomile oil used in a herbal bath can help to minimize the stinging and pain of sunburn. Comfrey and gotu kola tea can be made it to a compress for the affected area. Horsetail is good for tissue repair, while tea tree oil can help to heal sunburn and other skin irritation. Apple cider vinegar diluted with water is a great wash for sunburned areas.

To prevent sunburns, apply sunblock on any exposed skin before going out side to prevent skin damage before it starts.

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Pine Bark Extract
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Date: October 07, 2009 11:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pine Bark Extract

Pine Bark PictureMany Native American tribes relied on the bark of pine trees for its ability to treat a number of disorders. The Annedda pine was called the “tree of life” due to its marvelous healing benefits. Jacques Cartier, a noted explorer in 1535, wrote in his diaries about the early medicinal uses for pine tree bark. Cartier and his crew came down with scurvy after being caught in the bitter snows of Quebec and living on hard biscuits and cured meat. Multiple men died before Quebec Indians approached them and made a tea from the bark of a pine tree. After drinking the tea and applying poultices to their wounds, they were soon healed. The miraculous recovery is actually a result of the vitamin C and bioflavonoids in the bark. A French professor discovered Cartier’s account and became intrigued with studying pine tree bark. He isolated a certain kind of proanthocyanidin flavonoids from the extract and later found it to have antioxidant attributes.

Pine bark extract has become an important herbal remedy due to its antioxidant power. It is responsible for binding with collagen fibers and helping to restore elasticity in the skin. It also protects the body from Free-radical damage, which prevents excess and premature wrinkles. Pine tree bark also protects capillaries from Free-radical damage that can cause phlebitis, varicose veins, and bruising. Those people who are suffering from skin conditions like psoriasis can also be benefited from pine bark extract. Along with being an antioxidant, pine bark is a natural anti-inflammatory. It helps heal joint pain that is associated with things such as arthritis and sports injuries. This herb helps to control and prevent edema and bursitis. Pine Bark Picture Pine bark extract also helps with eyesight. It is responsible for reducing the risk of and treating diabetic retinopathy. Multiple studies have concluded that it is beneficial in improving night vision. One study even found marked improvement in visual performance in the proanthocyanidin group over a placebo group.

Additionally, pine bark extract may also help in inhibiting cellular mutations like tumors. Reports have found that this herb can help to prevent cellular deterioration in breast tumors and cardiovascular disease. There is also evidence that this herb possesses antiulcer properties that may help prevent the formation of undesirable chemicals in the stomach.

Pine bark can also benefit other conditions with its proanthocyanidin therapy. Among these are autoimmune disorders such as lupus, neural problems such as Parkinson’s disease and multiple sclerosis, and vascular problems like heart disease, atherosclerosis, and stokes. Pine bark extract can also treat common complaints such as insomnia, flu, and even the common cold. This herb is very helpful in improving memory, longevity, and the prostate.

Additionally, its stimulant properties are responsible for decreasing the production of histamines in allergic reactions like hay fever. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by pine bark extract, please feel free to consult a representative from your local health food store with questions.

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Ginkgo Biloba
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Date: October 01, 2009 11:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ginkgo Biloba

In the past decade, ginkgo has received much attention. It has been revered throughout China and other areas of Asia for thousands of years. However, its popularity increased in Western countries. An increase in sales can be attributed to interest in the benefits of ginkgo on conditions that are associated with aging like Alzheimer’s, memory loss, dementia, and circulatory disorders. Often, gingko is used to increase the blood flow to the brain, which improves memory problems like Alzheimer’s, to prevent strokes, and to increase blood circulation through vasodialation. The improved circulation is also thought to improve ear conditions, help blood flow to the retina, aid in preventing muscular degeneration, reduce frequency of asthma attacks, and help transplant recipients avoid rejection.

The ability of ginkgo to boost brain function has been studied extensively. Most importantly, ginkgo increases oxygen supply to brain cells, as the brain is the body’s most sensitive organ to oxygen deprivation. Additionally, ginkgo has been used to improve electrical transmission in nerves and supply more oxygen and nutrients to brain cells. The effect that ginkgo has on the brain and circulatory system disorders seems to be extremely promising for a variety of conditions. Ginkgo has also been found to be effective in treating migraine headaches. In one study that took place in 1975, ginkgo extract was given to individuals who were suffering from migraines. Results concluded that eighty percent of the patients showed improvement or were cured of the condition.

Ginkgo extract has also helped dementia that results from poor blood flow to the brain. Senile dementia is often recognized by depression, unusual fatigue, and memory problems. Ginkgo has the ability to help improve circulation to the brain tissue, which in turn improves brain function.

Blood platelet aggregation, or clotting, can cause serious problems in the body. Among these are strokes, heart attacks, and coronary thrombosis. It has been found that ginkgo can reduce the tendency for platelets to stick together and prevent them from forming clots in the arteries and veins.

The brain and nervous system are extremely sensitive to Free-radical damage because of the high percentage of unsaturated fatty acids. It has been found that ginkgo’s antioxidant activity is particularly powerful in these areas, along with the eye and retina. This is extremely helpful in conditions like retinopathy, cataracts and macular degeneration. The central nervous system possesses fat lipids in the cell membranes that are typically attracted by free radicals. Ginkgo can help protect these cell membranes and prevent condition which can occur in the brain and nervous system that are often associated with aging, like memory loss.

The leaves of the ginkgo plant are used to provide adaptogen, alterative, antioxidant, antiseptic, and stimulant properties. Primarily, ginkgo is extremely helpful in treating ADHD, Alzheimer’s disease, lack of attention span, blood clots, cardiovascular disorders, poor circulation, dementia, dizziness, edema, impotence, inflammation, ischemia, memory loss, lack of mental clarity, multiple sclerosis, muscular degeneration, PMS, Raynaud’s disease, senility, stress, stroke, and tinnitus.

Additionally, this herb is very helpful in dealing with allergies, angina, anxiety, arthritis, asthma, cancer, carpal tunnel syndrome, coughs, depression, lack of equilibrium, eye problems, hearing problems, hemorrhoids, lung disorders, migraines, mood swings, toxic shock syndrome, transplant rejection, varicose veins, vascular problems, and vertigo.

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Schizandra
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Date: August 04, 2009 12:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Schizandra

The schizandra plant belongs to the family of the Magnoliaceae family. The herb is a creeping woody vine that is native to both China and Japan. The fruit of the schizandra plant has a sweet, salty, bitter, hot, and sour taste. This explains the Chinese name for it, wu wei zi, which means five taste fruit. The seeds of the schizandra plant are both bitter and pungent. Along with the phytochemicals, schizandra is also rich in minerals, vitamins, and essential oils. Schizandra fruit can be found growing wildly in northern China. There, it has been used as a natural medicine for thousands of years. It is often prescribed by physicians in that region. The herb was listed in a book on pharmacy written in the sixteen century by Li Schizheng. Schizandra is used to increase energy; replenish and nourish the viscera, which are the internal abdominal organs; improve vision; boost muscular activity; and soothe both coughs and digestive upsets. In short, schizandra is an adaptogenic, Asian herb that is gaining popularity throughout the world.

This herb helps the body to heal itself. It can help increase energy in the cells of the brain, muscles, liver, kidney, glands, nerves, and the entire body. Schizandra good for adrenals and stimulates the immune system and protects against Free-radical damage, radiation, and the effects of sugar, as well as boosting stamina, normalizing blood sugar and blood pressure, and protecting against infections. This herb has a tonic action on the immune system, as well as other body system. For this reason, it can be taken regularly. Schizandra is able to help protect the body from both viral and bacterial infections.

Scientific research has determined that schizandra is antibacterial, stimulant, and protects the liver against toxins. Problems with the liver can lead to immune disorders because of the buildup of toxins. This herb has also been found to help allergies, depression, and fatigue in mice. The herb has been found to protect against the effects of alcohol in laboratory mice. Additional studies have determined that this herb has a mild regenerative effect on the liver. The herb has been used effectively in China to treat infectious hepatitis. Schizandra seems to have a liver-protective effect that is similar to that of milk thistle extracts.

In short, the berries of the schizandra plant are used to provide alterative, antibacterial, astringent, and sedative properties. The primary nutrients found in this herb are calcium, iron, magnesium, phosphorus, potassium, selenium, silicon, sodium, and vitamin C. Primarily, schizandra is extremely beneficial in treating diabetes, lack of energy, fatigue, impotence, lack of mental alertness, nervous disorders, and stress. Additionally, this herb is very helpful in dealing with aging, anxiety, arteriosclerosis, asthma, high blood pressure, coughs, diarrhea, edema, gastritis, heart palpitations, hepatitis, indigestion, infections, insomnia, kidney disorders, lung disorders, motion sickness, effects of radiation, uterine problems, and poor vision.

In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen. For more information on the many beneficial effects provided by schizandra, please feel free to consult a representative from your local health food store with questions.

Schizandra is available at your local or internet health food store in capsule or tablet forms. Always look for name brands of schizandra to ensure that you purchase a product that is high quality and pure.

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Boost Absorption With Natural Vitamins
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Date: April 17, 2009 11:20 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Absorption With Natural Vitamins

Malabsorption occurs when the body fails to properly absorb vitamins, minerals, and other nutrients from food. Even though a person’s diet is adequate, an individual with malabsorption develops various nutritional deficiencies. This problem is often the result of impaired digestion, impaired absorption of nutrients into the bloodstream from the digestive tract, or both.

Common symptoms of malabsorption syndrome include constipation or diarrhea, dry skin, fatigue, gas, mental difficulties such as depression or an inability to concentrate, muscle cramps and/or weakness, premenstrual syndrome, steatorrhea, a tendency to bruise easily, failure to grow normally, thinning hair, unexplained weight loss, and visual difficulties especially with night vision. Abdominal comfort may also be present and a combination of anemia, diarrhea, and weight loss is typical. However, in some individuals, obesity may result if fats are deposited in the tissues rather than being utilized properly by the body. Additionally, the body may begin to crave more and more food, which often leads to the consumption of many empty and/or fat calories.

Factors that can contribute to a malfunction of the absorption mechanism include digestive problems, poor diet, excess mucus covering the intestinal lining, an imbalance in intestinal bacterial flora, the use of certain medications, food allergies, and illnesses such as cancer and AIDS.

No matter how good your diet is or how many supplements you take, you will have nutritional deficiencies if you suffer from malabsorption syndrome. These deficiencies lead to other problems. The impaired absorption of protein can cause edema, while a lack of potassium can cause muscle weakness and cardiovascular problems. Anemia results for a lack of iron and folic acid, while bone loss and tetany can be caused by a lack of calcium and vitamin D. Bruising easily results from a lack of vitamin K, while night blindness comes from a deficiency of vitamin A. The failure to absorb B vitamins and to transfer amino acids across the intestinal lining interferes with the production of needed digestive enzymes and causes further malabsorption, as these nutrients are essential in the absorption process itself. This causes a vicious cycle to be produced.

Malabsorption is a factor in other medical and physical problems, along with being a serious condition in itself. The body needs all nutrients in balance because they have to be able to work together. If there is a deficiency in even a single nutrient, the body no longer functions as it should, allowing all things to go awry. This results in disease. Malabsorption is a common contributing factor to a wide range of disorders, including cancer, heart disease, osteoporosis, and all types of infection.

People with malabsorption syndrome must take in more nutrients than the average person to compensate, and to treat and correct the problem. It is best to bypass the intestinal tract as much as possible when supplying these nutrients. As a result, choosing supplements that are sustained-release and large in size should be avoided. Many people with malabsorption problems can not break down supplements taken in hard pill form. Therefore, injections, powders, liquids, and lozenges provide nutrients in forms that are more easily assimilated.

The following nutrients are recommended for dealing with malabsorption syndrome: acidophilus, vitamin B complex, bioperine, calcium, Free-form amino acid complex, garlic, magnesium, vitamin C with bioflavonoids, vitamin E, essential fatty acids, a multi-vitamin and mineral complex, proteolytic enzymes, and zinc lozenges. Additionally, the following herbs may be beneficial: alfalfa, dandelion root, fennel seed, ginger, nettle, aloe vera, peppermint, black pepper, buchu, goldenseal, irish moss, rhubarb, and yellow dock.



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Healthy Nails
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Date: March 03, 2009 12:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Healthy Nails

The nails are responsible for protecting the nerve-rich fingertips and tips of the toes from injury. Nails are part of the epidermis, which is the outer layer of skin. They are mainly composed of keratin, which is a type of protein. The nail bed is the skin on top of which the nails grow, as they grow from 0.05 to 1.2 millimeters each week. If a nail is lost, it takes approximately seven months for it to grow out fully.

Those nail beds that are healthy are pink, which indicates a rich blood supply. Changes or abnormalities in the nails are often a result of nutritional deficiencies or other underlying conditions. The nails are able to reveal a great deal about the body’s internal health. Nail abnormalities on either the fingers or the toes can give evidence to an underlying disorder.

There are many changes that nutritional deficiencies can produce in the nails. A lack of protein, folic acid, and vitamin C are responsible for hang nails, while white bands across the nails are an indicator for protein deficiency. Dryness and brittleness indicates a lack of vitamin A and calcium. Horizontal and vertical ridges in the nails means that there is a deficiency of the B vitamins, while an insufficient intake of vitamin B12 can lead to excessive dryness, very rounded and curved nail ends, and darkened nails. Iron deficiency can lead to nails that develop a concave shape and/or vertical ridges. White spots on the nails can be caused by a deficiency of zinc. Inadequate amounts of friendly bacteria in the body can result in the growth of fungus under and around the nails, while a lack of hydrochloric acid contributes to the splitting of nails.

The following supplements are essential in promoting healthy nail growth. Unless otherwise specified, the dosages given are for adults. For children between the ages of twelve and seventeen, the dose should be reduced to three-quarters of the recommended amount. For children between six and twelve, one-half of the recommended dose should be used, while one-quarter of the amount should be used for children under the age of six.

Acidophilus should be taken as directed on the label, as it inhibits the harmful bacteria that cause fungal infection. A Free-form amino acid complex can also be taken as directed on the label, on an empty stomach, to provide the building materials for new nails. Silica supplies silicon, which is needed for hair, bones, and strong nails. It should be taken as directed on the label. Vitamin A emulsion should be taken in dosages of 50,000 IU daily, as the body cannot utilize protein without vitamin A. Black currant seed oil is helpful for weak, brittle nails and should be taken in dosages of 500 mg twice daily. Calcium and magnesium should be taken as directed on the label, as they are necessary for nail growth.

Iron should be taken as directed by a physician, as deficiency produces spoon nails and/or vertical ridges. A vitamin B complex should be taken as directed on the label, as deficiencies result in fragile nails. To prevent hangnails and inflammation of the tissue surrounding the nail, 3,000 to 6,000 mg daily of vitamin C with bioflavonoids should be taken. 50 mg daily of zinc is beneficial for affecting absorption and action of vitamins and enzymes.

Additionally, the following herbs are helpful: alfalfa, black cohosh, burdock root, dandelion, gotu kola, yellow dock, horsetail, oat straw, borage seed, flaxseed, lemongrass, parsley, primrose, pumpkin seed, sage, butcher’s broom, chamomile, ginkgo biloba, rosemary, sassafras, and turmeric.

Healthy looking nails can tell you if your body is getting the right nutrients from your diet. When you find your nails are not looking well, consider the above vitamins, minerals and herbs to help restore healthy looking finger and toe nails. The vitamins and herbs listed can be found at your local or internet health food store.

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Mumps
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Date: February 27, 2009 02:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mumps

Mumps, a common viral illness mostly occurring during childhood, is caused by a type of virus that is known as a paramyxovirus that infects the parotid glands, which are the salivary glands that are located at the jaw angles below the ears. Symptoms include swelling of one or both glands plus headache, fever, chills, decreased appetite, sore throat, and pain when swallowing or chewing, especially when swallowing acidic substances such as citrus juices. A lot of times, one of the parotid glands will swell before the other, and as swelling in one gland subsides, the other begins to swell. Mumps travels from person to person by means of infected droplets of saliva or direct contact with contaminated materials. This illness can be contracted through sneezing, coughing, kissing, talking, breathing, drinking out of the same glass as an infected person, and sharing utensils. This virus has an incubation period that can vary from fourteen to twenty-four days, with the average period being about eighteen days. A person with mumps is contagious any time from forty-eight hours before the onset of symptoms to six days after the symptoms have started. Although this attack is not as contagious as measles or chickenpox, it is similar in that one attack usually gives lifetime immunity.

Mumps occurs most commonly in those children that range between the ages of three and ten. However, it can occur through teenage years and, rarely, in adulthood. If this illness does occur after puberty, the ovaries or testes may become involved and sterility may result. If the testicles are affected, they become swollen and painful, while abdominal pain will result if the ovaries or pancreas is affected. Other organs that can be affected by mumps in rare or severe cases include the brain, pancreas, and kidneys. All of these can potentially cause serious complications.

The following bacteria are beneficial in dealing with mumps. Unless otherwise specified, the dosages given are for adults. For children between the ages of twelve and seventeen, the dose should be reduced to three-quarters of the recommended amount. For children between six and twelve, one-half of the recommended doses should be used, while one-quarter of the amount should be used for children under the age of six. Bifidobacterium bifidus should be taken as directed on the label to provide friendly bacteria, which contains antibiotic substances that inhibit pathogenic organisms. Vitamin C with bioflavonoids helps to destroy the virus and eliminate toxins if taken in dosages of 500 mg every 2 hours until improvement is noted.

One 15 mg zinc lozenge should be taken every 4 to 6 hours to aid healing. Acidophilus should be taken as directed on the label, as it contains antibiotic substances that inhibit pathogenic organisms. A Free-form amino acid complex should be taken as directed on the label, as it is important for tissue repair and healing. 50,000 IU of vitamin A with mixed carotenoids should be taken daily, as it potentates immune function. Kelp, which contains essential minerals, iodine, and vitamins, should be taken in dosages of 1,000-1,500 mg daily. Additionally, the following herbs are beneficial in dealing with mumps: catnip, chamomile, dandelion, Echinacea, elderflower, lobelia, mullein, peppermint tea, slippery elm bark, barley, and yarrow.

Vitamin supplements are great to help fight off colds, but with the mumps always consult your doctor, if left untreated further life threatening complications may occur which is not desirable by anybody. Vitamin and Herbs are available at your local or internet health food store.



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Date: February 23, 2009 11:54 AM
Author: Darrell Miller (dm@vitanetonline.com)

Mononucleosis is an infectious viral disease that is most often caused by the Epstein-Barr virus. More rarely, it can be caused by cytomegalovirus. Both of these viruses are members of the herpes family. Once the virus enters the body, it multiplies in lymphocytes. Mono then affects the respiratory system, the lymphatic tissues, and glands in the neck, groin, armpits, bronchial tubes, spleen, and liver.

Symptoms of mono include depression, extreme fatigue, fever, generalized aching, headache, jaundice, and loss of appetite, sore throat, pain on the upper left side of the abdomen, puffy eyelids, swollen glands, and sometimes, a bumpy, red rash. Additionally, the spleen may become enlarged and liver function may be affected. Meningitis, encephalitis, and rupturing of the spleen are very rare complications that may develop as a result of mono.

The virus’s associated with mono are extremely contagious, often being transmitted from person to person by close contact such as kissing, which explains why mono is often referred to as the “kissing disease.” The disease can also be spread by sharing food or utensils, as well as through sexual contact or through respiratory droplets. The incubation period for mono is about ten days in children and thirty to fifty days in adults. A lot of mononucleosis cases occur in the military and in colleges, as living conditions are crowded and sleeping patterns are inadequate. High school students also have a high incidence of this disease. Mono is most common among children and adolescents, as about 90 percent of people over age thirty-five have mono antibodies in their blood, which means that they had the disease at some point in their lives, although many do not even know they had it.

The symptoms of mononucleosis are very similar to those of influenza, which often results in mono often being mistaken for it. However, with mono, the symptoms tend to be more persistent, with acute symptoms usually lasting from two to four weeks, and fatigue persisting for three to eight weeks after the other symptoms disappear. The disease can even linger for a year or more in some individuals. It can also produce recurring, but successively milder, attacks. If the immune system has been compromised by an organ transplant, HIV/AIDS, or other viruses, the mono symptoms can be extremely serious and chronic.

Mononucleosis is diagnosed through a blood test called a spot test. This test reveals the presence of specific viral antibodies and also confirms the presence of mono. Additionally, a liver function test can assist in the diagnosis.

The following nutrients are considered to be extremely important in dealing with mononucleosis: acidophilus, proteolytic enzymes, vitamin A with mixed carotenoids, and vitamin C with bioflavonoids. Other nutrients that have proven to be both important and helpful include: DMG, a Free-form amino acid complex, garlic, vitamin B complex, zinc lozenges, maitake extract, reishi extract, shiitake extract, a multivitamin and mineral complex, and raw thymus glandular.

Astragalus and Echinacea are also beneficial in boosting the immune system, while cat’s claw has immune-enhancing properties that act against viral infections. Dandelion and milk thistle are beneficial in protecting the liver. Goldenseal helps to fight infection, while olive leaf extract helps to inhibit the growth of viruses that cause mono. Pau d’arco balances the bacteria in the colon and spirulina contains phytonutrients that are helpful in boosting the immune system.

Whether you want to combat mono symptoms naturally or use prescription drugs, always consult your family physician before taking matters into your own hands. A correct diagnosis is important to how one might want to combat sickness in general. Natural vitamins like the ones listed above are available at your internet health food store.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Alpha Lipoic Acid
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Date: December 11, 2008 11:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Alpha Lipoic Acid

Alpha lipoic acid is the ideal antioxidant for five main reasons. It can scavenge free radicals of all kinds of both fat and water-based cell structures. It rapidly assimilates and absorbs into cells. Alpha lipoic acid boosts the action of other protective compounds. It chelates free meal ions and it also promotes normal cell replication.

Alpha lipoic acid (ALA) is both fat and water soluble, which makes it a superior Free-radical scavenger because it can protect lipid (fat) and aqueous (water) cell parts from Free-radical damage. This ability allows ALA to offer excellent cellular protection because it can easily transport across cell membranes and give oxidant protection outside and inside cell structures. ALA has the ability to freely move throughout all cell parts, scavenging for free radicals in a way that is definitely more effective than other antioxidant compounds. Vitamin C, for example, is a good antioxidant but is strictly water soluble and only affects the interior of cells. On the other hand, vitamin E is only fat soluble, meaning that it affects only the lipid portion of cell structures or the membrane, which leaves other areas unprotected.

Cellular glutathione, which is produced in the body and works to neutralize free radicals, is very difficult to artificially boost. Although oral glutathione supplements are available, they have to go through the GI route before they enter the blood stream, leaving little glutathione which actually survives this process. Because of this, cellular levels are not significantly increase by oral supplementation. ALA has been found to help regenerate glutathione by providing extra cellular protection.

If the body becomes deficient in ALA, other antioxidant compounds may not work well. ALA plays an important role in boosting the activity of protective compounds such as vitamin E. ALA dramatically extends the life and effectiveness of other vital compounds.

ALA has been used for decades to treat diabetic conditions and complications including diabetic neuropathy, with ALA actually having the ability to initiate a reverse in the condition in some cases. Additionally, ALA helps to boost glucose uptake and results in less insulin dependency in some cases. Among its other properties, ALA can protect brain tissue on a cellular level, as well as protect brain cells from certain hazardous chemicals.

Research has shown that ALA may even play a role in the treatment of neurological disorders such as Huntington’s disease. As we are all aware, LDL cholesterol has a huge role in the development of cardiovascular disease. LDL cholesterol, which is particularly susceptible to Free-radical damage, can be protected by ALA from free radical damage itself. Along with the above properties, ALA has been shown to help in strokes, cancer, cataracts, HIV, liver regeneration, and detoxification.

ALA can be purchased in tablet and capsule form and works well when it is orally ingested so that it can be easily assimilated through the walls of the gastrointestinal tract. Taking between 40 to 50 mg of ALA is recommended for best results. The primary applications of alpha lipoic acid are aging, aids, alcoholism, atherosclerosis, bell’s palsy, cataracts, cancer, cirrhosis, diabetes, diabetic neuropathy, multiple sclerosis, liver disease, radiation sickness or exposure, Alzheimer’s disease, senile dementia, stroke, Huntington’s disease, Parkinson’s disease, and heavy-metal poisoning. Have you had your alpha lipoic acid today?



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What is Alpha Lipoic Acid?
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Date: July 18, 2008 12:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Alpha Lipoic Acid?

You can be sure that a supplement has some remarkable therapeutic possibilities when it makes headlines on the five o’clock news. A recent experiment which showed the conditions of rats that had been fed a diet that was totally deficient in vitamin E tested alpha lipoic acid, which caused the rats to return to full health even though no vitamin E was replenished. The results of this test are profound, as giving these rats an alpha lipoic acid caused existing stores of vitamin E that the body was previously unable to use to be regenerated.

Alpha lipoic acid is a vitamin-like antioxidant that has been used in Europe for a long period of time. It has recently emerged as an extremely impressive therapeutic agent that scavenges Free-radicals. Recent studies have suggested that it has the ability to stop some degenerative diseases, the oxidative process of aging, and restores the health of diseased organs. Additionally, it has the ability to make up deficits of vitamin E or C and could potentially be one of the best treatments that have emerged for diabetes. Alpha lipoic acid (ALA) is considered to be more potent than vitamins E and C, as well as coenzyme Q10. Unlike other antioxidants, ALA has properties that make it superior because it is able to replace certain nutritional supplements, while potentiating others, and inhibiting tissues from deterioration that is associated with diseases. This supplement is also both fat and water soluble, which allows it to protect lipid and aqueous cell structures.

Alpha lipoic acid is a compound that is synthesized in small amounts in the body, but can also be supplied from food or supplement sources. A vitamin-like substance, it contains sulfur and also plays a crucial role in energy reactions. It can be found in liver, yeast, spinach, organ meats, broccoli, red potatoes, and red meat. When it is orally ingested, alpha lipoic acid is not compromised in the GI tract or the liver.

Numerous studies have been conducted on ALA, all of which confirm its positive effect on metabolic processes, with recent clinical tests supporting its ability to enhance Free-radical protection, slow the aging process, and guard against a variety of degenerative diseases. ALA was discovered in the 1930s, where it was originally classified as a vitamin, and later categorized as an essential coenzyme when scientists discovered that it was involved in the energy processes of cell mitochondria. It wasn’t until 1988 that scientists found that it also has powerful antioxidant effects.

Alpha lipoic acid is important because it protects us from Free-radicals which are present in a body as a result of the number of toxic substances such as auto exhaust, tobacco smoke, pollution, preservatives, and additives that we are exposed to on a daily basis. These free radicals can actually accelerate the aging process, causing premature tissue breakdown to occur. Additionally, our environment will continue to surround us with these pollutants that create free radicals.

There are things we can do to minimize our health risks, which include exercising, eating nutritiously, and not smoking. However, these measures are rarely enough to decrease our risk for certain degenerative disease a substantial amount. ALA is beneficial because it scavenges oxidants that are left behind and helps to convert carbohydrates, fatty acids and protein to energy that is needed to drive muscle movements.

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Advocacy Update
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Date: May 17, 2008 10:17 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Advocacy Update

Recently, the Natural Products Association has experienced a flurry of activity on the legislative front. One month ago, Natural Products Association members went to Washington, D.C. to meet with their representatives and discuss legislation important to the association and the industry. Many who could not visit Washington in person were part of our "virtual march" on Washington that delivered e-mails, petitions, and videos to Congress on the importance of natural products. Natural Products Day was a great success, boasting higher than ever attendance at our evening Congressional reception, and resulting in additional co-sponsors for S. 771, the Child Nutrition Promotion and School Lunch Protection Act sponsored by Tom Harkin (D-Iowa). The bill now boasts co-sponsorship of more than a quarter of the Senate. Its companion bill in the House of Representatives, H.R. 1363, sponsored by Lynn Woolsey (D-Calif.), has gained an additional five co-sponsors as the result of Natural Products Day meetings and now has 140 co-sponsors. These bills continue to build momentum, thanks to your support.

More recently, the Natural Products Association urged supporters to contact their legislators to include an amendment to the "Farm Bill" allowing food stamp recipients to purchase dietary supplements. This provision was similar to Free-standing bills that have been introduced in the current and previous Congresses by Sens. Harkin and Orrin Hatch (R-Utah) and have earned the association's support. Although the amendment advanced further than other versions in previous sessions, it did not make the final Farm Bill, which was reported out of conference today. The good news is that the Farm Bill did contain significant increases in nutrition programs and increased funding for organic farming, another supported goal of the Natural Products Association. Because of the strong effort of our supporters on the amendment's behalf, the bill was placed on Congress's radar screens and has greatly improved the chances as stand-alone legislation, S. 770, the Food Stamp Vitamin and Mineral Improvement Act, of seeing passage. We will continue to ask for support on this important bill as this legislative session progresses.

In addition, the Natural Products Association has been leading the fight to protect Dehydroepiandrosterone (DHEA), and to keep this important, safe, and effective supplement available to elderly consumers. The same players behind S. 762, which would wrongly classify DHEA as an anabolic steroid, proposed S. 2470 in late 2007 as a misplaced reaction the release of the Mitchell Report, which chronicled the abuse of steroids by professional baseball players. Although DHEA has no performance enhancing attributes, this bill was proposed to limit the access of minors to DHEA. The Natural Products Association and its supporters have worked hard to inform Congress of the benefits of DHEA, and that it is not an anabolic steroid and should not be classified as one. We have been able so far to prevent any movement on the bill, but the association continues to monitor its progress and make sure that this supplement remains accessible to the seniors who need it most.

Thanks to your help, the Natural Products Association continues to have an active presence on Capitol Hill that is felt by legislators. We could not do it without the help of you, our supporters, who know how important it is to stand up for natural products. The impact of your messages to legislators continues to help the Natural Products Association to ensure all natural products - from natural and organic foods to dietary supplements and health and beauty aids - are accessible to Americans. With your continued support we will continue to be known as a vocal group with a wide base of support through the rest of this legislative session and beyond.

To get involved, please visit our action center at www.capwiz.com/nnfa/issues/



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Papaya- May Be A Fountain of Youth
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Date: May 31, 2007 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Papaya- May Be A Fountain of Youth

Papaya- May Be A Fountain of Youth

 

Seventy years ago, when the Social Security Administration was developed during the Great Depression, age 62 was recognized as average life expectancy. These days, getting older is a whole different ball game. Not only are people living well into their 80s and 90s, they’re living better, too. People well into retirement are mountain biking, kayaking, jogging and hiking, as well as gardening, golfing and attending concerts – sometimes for their first time. Everybody, it seems, is on the go, from ages of 22 to 92.

 

Of course, you don’t have to wait until retirement to start planning for a longer more vibrant life. The best way to ensure happier and longer years ahead is to start young.

Nobody wants to spend retirement in the doctor’s waiting room or have their golden years intruded upon with illnesses or infirmities. And, most importantly, we don’t want to feel 80 years old even though our driver’s license says we are.

These desires and demands are not just wishful thinking. Huge advances in the understanding of how men and women age are being made almost daily. These findings are helping to improve our chances of living long, healthy lives. And, some of the most impressive findings have shown that using nutritional supplements can help – in particular, a specially formulated papaya preparation is able to fight two of the primary reasons we get old – oxidative stress and immune system decline.

This issue of Ask the Doctor is going to share the anti-aging secrets hidden in the papaya and how this tropical fruit may hold the key to a long, vibrant life.

 

Q. Why papaya? What does papaya have that other fruits and vegetables don’t?

A. Not many American moms put a papaya in their kids’ lunch boxes and papaya pie has yet to gain a following. But this tangy tasting fruit is now appearing fairly frequently in the produce departments of most grocery stores and its popularity seems to steadily increase each year.

The papaya’s bright orange flesh is fairly fibrous and very slippery – slicing a peeled papaya is a little like slicing a bar of wet soap. The core is filled with little black seeds that look a lot like caviar. And while eating a papaya will give you a day’s worth of vitamins A and C as well as potassium taking Fermented Papaya Preparation (or FPP) might just give you an additional 30 years of healthy vibrant life.

 

Q. What exactly is Fermented Papaya Preparation (FPP)?

A. It’s a specialized nutritional supplement. Backed by more than 30 studies to date, FPP has been used in Japan for decades. It’s also an extremely popular supplement in France and other parts of Europe. FPP begins with fresh, ripe papayas that are slowly fermented by a natural process that takes several months to complete. The fermented papaya is then dried and ground into a fine powder. This phytonutrient-rich powder can then be sprinkled in the mouth, dissolved, and swallowed.

 

Q. How was FPP developed?

A. Japanese scientists noticed that individuals with higher amounts of papaya in their diets experienced certain health benefits.

Researchers who study aging decided to look at the papaya’s chemistry to see if it might have properties that could contribute to longevity. Several plant chemicals in the papaya showed promise. And when they combined papaya with specific yeasts and traditional Japanese fermentation techniques, FPP was born. This unique substance was then subjected to scientific studies to see its health impact; they determined that FPP is a superior antioxidant, a powerful immune-booster, and one of Japan’s secrets to a long healthy life.

 

Q. How does FPP help people live longer and healthier?

A. While getting older is an indisputable fact of life, aging, per se, is not. We can’t do much about our annual birthdays and we really shouldn’t even if we could. Every age is a cause for celebration and every life experience, both the difficult and the sublime, should be treasured.

However, we don’t have to accept the consequences of aging that can make a mockery of the “Golden Years” - heart disease, Alzheimer’s disease, Parkinson’s disease, osteoporosis, arthritis, and cancer. Our parents and grandparents and the generations that preceded them might have had little say in how they aged. But we can. We can slow down the harmful effects of aging and FPP can help by reducing oxidative stress and immune system decline.

Additionally, fighting oxidative stress helps people retain their youthful appearance longer. Oxidative damage is the number one factor in facial aging.

 

Q. What exactly does oxidative stress mean and what does it have to do with aging?

A. One theory of aging is that harmful molecules called free radicals wreak havoc in our cells. Many of our body’s normal metabolic processes produce free radicals. For example, free radicals are a normal by-product in the production of ATP (the energy molecule) from glucose. Certain types of white blood cells destroy invading microbes by the production of free radicals. Free radicals are also formed by the many normal enzymatic actions that take place every minute every day.

However, outside sources can also cause free radical formation, as well. If we are exposed to pollutants in the environment, chemicals, additives and preservatives in the food we eat, or even direct sunlight, excess production of free radicals can occur, causing profound damage. This free radical frenzy is called oxidative stress, and is linked to almost every disease of aging including arthritis, heart disease, cataracts, Alzheimer’s disease, Parkinson’s disease, and cancer. In fact, the reason why these are called diseases of aging is because the longer we are alive, the longer we are subjected to these free radical assaults.

 

Q. How does FPP affect the decline of our immune systems as we age?

A. Our immune systems consist of specialized tissues, organs, and cells, including several different kinds of white blood cells. Each type of white blood cell works in specific ways to keep us healthy and free of disease. They not only stand guard – on the alert for invaders – they can fight and eradicate microbes, too.

However, as we age, our white blood cells become less efficient in keeping viruses and bacteria from infecting us. They often mistake invaders for good guys, like nutrients. As they age, white blood cells may recognize foreign invaders, but be too tired to fight and let them in. This age-associated immune decline also results in single cancer cells being able to “take hold” and grow into tumors. By the time the white blood cells realize their mistake, the cancer is a widespread disease.

That’s why older members of society have more urinary tract infections, more pneumonia, more cases of bacterial meningitis, tuberculosis, herpes zoster, and much more cancer than younger adults do. Moreover, mortality rates for these diseases are often 2-3 times higher among adults than younger people with the same disease.

FPP steps in and takes charge. One kind of white blood cells, the macrophage “eats” and digests bacteria, viral particles, and free radical fragments. Research has shown that FPP helps macrophages work faster and ingest more disease-causing microbes. Scientists have also discovered that FPP increases the production of a chemical protein called interleukin that’s secreted by macrophages. Interleukin plays an important part in wound healing and keeping minor infections from becoming major infections.

Another important immune system cell is the natural killer (NK) cell, a white blood cell that is continually on the prowl for cancer cells. As the immune system ages, NK cells have trouble “seeing” cancer cells. Researchers have discovered that FPP boosts the activity of NK cells. Increased NK cell activity can result in the increased killing of cancer cells as well as cells infected by viruses.

 

Q. How does FPP help protect us from free radical damage?

A. FPP contains unique and powerful antioxidants. Antioxidants are molecules that neutralize free radical damage. Antioxidants do this by donating an extra electron to the free radical without becoming frenzied or worked up into a free radical themselves. Although the antioxidant has donated an electron, it has a more stable “personality” and is less reactive. This action stops the domino effect and ongoing Free-radical damage.

If you consider your body a temple, think of free radicals as stealing bricks from your temple’s foundation. FPP acts not only as policeman, but as a builder as well. It doesn’t just stop the theft of bricks; it helps create new ones, keeping the foundation strong and young.

FPP does this by affecting super oxide dimutase (SOD) and glutathione peroxidase (GPX), the very genetic pathways that eliminate free radicals from the system. FPP is more than an antioxidant – it doesn’t turn into a pro-oxidant if you happen to take a large dose the way standard antioxidants can. Consider it an “antioxidant plus.”

Since aging is largely determined by how well our bodies can fight oxidative damage, using FPP can slow down the clock as it bolsters natural abilities with its own potent neutralizing activities.

 

Q. What else does science say about FPP?

A. As the subject of over 30 clinical studies, FPP has been shown to inhibit dangerous hydroxyl free radicals. In addition, it is also being considered for its immuno-protective effects.

Researchers and medical professionals have been studying FPP for years, tracking its effect on the immune system and aging. In fact, no less a personage then Dr. Luc Montagnier, co-discover of HIV 1 & 2 virus, has been conducting research on this natural immune booster.

Dr. Montagnier recommends using FPP as part of a tri-therapy (including antibiotics) that reduces the proliferation of the virus and stimulates the immune system. Since FPP has antioxidant and immuno-stimulative properties, it seems like an obvious choice for a combined approach to combating AIDS. Because of the higher free radical production in stage II of HIV infection, Montagnier believes that reducing this oxidative stress at the earliest stage of HIV infection may be a key factor.

In HIV-infected patients, the glutathione system is depressed even at the early stages. As part of a combination treatment, FPP increased the numbers of CF4 lymphocytes helped with weight gain and increased hemoglobin levels.

One scientific study showed the ability of FPP to inhibit dangerous hydroxyl and hydroxyl-like free radicals, while enhancing the production of protective super oxide. Other research by Dr. Lester Packer, a professor of Molecular Pharmacology and Toxicology at the University Of Southern California School Of Pharmacy, shows FPP to have natural iron chelating effects and prevents lipid peroxidation.

And, in one randomized, double blind, placebo-controlled clinical trial, patients with cirrhosis of the liver were given FPP or a placebo. The results showed that 81.2% of the patients survived in the FPP group compared to 38.5% of participants in the placebo group.

These studies and many others like it, show that FPP can neutralize the effects of oxidative stress on disease states as well as slowing the normal aging process.

 

Q. So if we can prevent oxidative damage to our cells AND prevent decline in our immune systems, how much longer can we expect to live?

A. Most theories of aging and almost all researchers who study aging claim there IS a limit to how long the human body can remain viable. However, the oldest age achieved so far was 128 by a woman named Ma Pampo who lived in the Dominican Republic. Other notable oldsters include Jeanne Louise Calment of France, who lived to be 121; Elena Slough, of Trenton New Jersey who lived for 114 years and 112-year old Mary Dorothy Christian who lived and died in San Pablo, California.

Right now, Japanese women have the longest life span of any country in the world, with an average life expectancy of 85.93 years. Japanese men live an average 78.87 years. Japan also has more centenarians – people living to age 100 and beyond – than any other country as well. There is no reason why the rest of the world, the USA included, can’t achieve these average life expectancies and, hopefully, even surpass them.

 

Q. Is FPP safe?

A. Yes, it is. Many health-conscious people in Japan and Europe have used FPP for many years as an anti-aging product without any side effects.

 

Q. What is the recommended dosage level of FPP?

A. Dosages of FPP vary depending on individual needs and usage. For basic anti-aging support, 3 grams per day is fine. For additional support, up to 9 grams per day is recommended. To add a boost to your immune system when you need it, start out with 6-9 grams a day for the first 2-3 days (at the beginning of a cold, for example) and then move back down to 3 grams per day.

For individuals looking for optimum immune support, Dr. Montagnier advises morning and evening doses, preferably on an empty stomach.

 

Conclusion

As America’s Baby Boomers turn 65, they are living proof that the milestone is no longer the herald of old age. It’s just one more stepping stone from where we’ve been – to where we are – and on to where we want to go. Using Fermented Papaya Preparation, we can feel younger, look younger and live younger – to a very old age.



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The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
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Date: May 18, 2007 01:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium

The Awesome Foursome: Coenzyme Q10, L-Carnitine,

D-Ribose, Magnesium

 

The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.

 

Coenzyme Q10:

Energy Recycling through the Electron Transport Chain

Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from Free-radical attack. But its most important function in the body is its central role in energy metabolism.

Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.

In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.

What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.

Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.

 

L-Carnitine:

Transporting the Cellular Energy Fuel

Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.

 

D-Ribose:

Rebuilding the Cellular Energy Pool

As long as cells and tissues have plenty of oxygen, the pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.

When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.

Ribose is the only compound used by the body to refill this energy pool.  Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency.  Ribose is made naturally in the cells from glucose.  In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis.  So when energy pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.

    Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy.  Even when oxygenated blood flow returns, refilling the energy pool may take ten or more days.  But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the pool can ever refill without the assistance of supplemental ribose.  Conditions like ischemic heart disease or congestive heart failure fall into this category.  In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.

 

Magnesium:

Switching on the Energy Enzymes

Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism.  Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work.  Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.

    Magnesium deficiency reduces the activity of important enzymes used in energy metabolism.  Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function.  Small changes in magnesium levels can have a substantial effect on heart and blood vessel function.  While magnesium is found in most foods - particularly vegetables - deficiencies are increasing.  Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.

 

Supporting the Links in The Energy Cycle Chain – the Synergy

Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.

The cell needs a large, sustained, and healthy pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.

The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy pool supplied with substrate, but the value of energy pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.

Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.

These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.

The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.

L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.



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Do you experience muscle pain and inflammation?
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Date: April 25, 2007 03:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Do you experience muscle pain and inflammation?

FlexAgility MAX

 

Everyone experiences muscle pain and inflammation due to overuse and exertion. We’ve all had those softball games, weekend camping trips or chore-intensive days when our body lets us know we’ve overdone it.

So, what can you do about it? Well, fortunately, there is a proprietary formula with clinically studied ingredients that provides a natural solution: FlexAgility MAX.

FlexAgility MAX is designed to reduce pain and inflammation due to overuse. Its clinically studied ingredients have been shown to help balance the body’s own inflammatory response. Let’s take a look at FlexAgility MAX and answer a few questions you may have about it.

 

Q. What is inflammation? Why does it happen?

A. Inflammation is actually an essential part of your body’s natural healing process. When some form of physical stress affects the body, the immune system responds by supplying defensive compounds to the stressed site. This is what causes the fluid build-up, pain and redness we typically associate with inflammation. And until the situation is resolved those symptoms will stick around. So, why is that good? Because without these signals – pain and inflammation – we’d probably do even more damage. In a sense, pain and inflammation are very effective stop signs.

The problem is, if our bodies are continuously bombarded by factors that trigger inflammation, these defenders (and their symptoms) are always around. This can mean unnecessary pain and inflammation following overuse and exertion.

 

Q. What does FlexAgility MAX have to do with inflammation?

A. FlexAgility MAX provides triple-action activity against occasional pain and inflammation, with powerful antioxidant Free-radical scavengers, the enzyme bromelain, and a natural COX-2 inhibitor.

 

Q. So what is COX-2 and why should I inhibit it?

A. We’ve all been hearing a lot in the news about COX-2 inhibition and may have wondered about its connection to pain and inflammation. Let’s take a look:

Cyclooxygenase is an enzyme that comes in two main types, abbreviated for convenience: COX-1 and COX-2. The COX enzymes regulate compounds involved with inflammation, including prostaglandins. COX-1 is found throughout the body, and maintains the integrity of the stomach lining, circulation and kidneys.

COX-2 on the other hand, cruises along the central nervous system – it’s much more attuned to our brain’s sense of “what hurts.” Primarily activated by inflammatory stress, COX-2 generates prostaglandins – the hormone-like defensive compounds that cause the responses we associate with pain and inflammation due to overuse.

You can understand why so much research has focused on COX-2 inhibition. Decreasing its activity means short-circuiting the “inflammation cascade” that follows occasional overuse.

Because COX-1 is associated with a healthy stomach lining, it is not an enzyme you want to inhibit. Unfortunately, many products don’t know the difference between COX-1 and COX-2 – filing both with one blast.

Fortunately, there are ingredients in FlexAgility MAX that can tell them apart. One of them is IsoOxygene.

IsoOxygene is a patented hops extract shown in scientific studies to significantly inhibit COX-2, while leaving COX-1 alone. And, it is a 20 times more potent COX-2 inhibitor than other tested popular botanic products, including curcumin and grape seed.

 

Q. How do antioxidants support the body during times of inflammation due to overuse?

A. Overall, the body ahs a pretty darn good repair system. However, oxidative stress due to free radical damage can take its toll, especially during times of occasional physical stress. Free radicals and reactive oxygen species can damage cells, because they are hungry, unstable molecules in search of electrons. To find them, they attack other cells. These pillaged cells then become free radicals themselves, setting off a chain reaction of oxidative stress.

Free radicals are formed during the body’s normal functions, and can have benefits, such as neutralizing viruses and bacteria. However, in doing do, they erode the body’s own antioxidant defenses, too. And, free radicals typically become very active during times of inflammation due to overuse or other stressors.

The good news is that the herbal and antioxidant elements in FlexAgility MAX help support the body’s own natural anti-inflammatory defenses.

Take vitamin C, for instance. This extremely well-known antioxidant has been scientifically studied for its beneficial effects on muscle, collagen and connective tissue health. Collagen and connective tissue is what helps hold us together – literally.

And famous antioxidant, green tea, has been well-studied for the benefits of a polyphenol called epigallocatechin-3-gallate, or simply EGCG. In scientific and clinical studies, EGCG from green tea works as an overall antioxidant, scavenging free radicals, and supporting healthy collagen. In fact, one study showed that green tea polyphenols supported collagen health by 50% versus only 16% in controls.

The green tea extract in FlexAgility MAX is especially focused on these beneficial polyphenols. It’s standardized to contain 70% polyphenols – half from EGCG. The green tea acts in concert with elderberry and ginger in the formula to help prevent oxidative stress to the body due to occasional overuse.

Anthocyanins are natural antioxidants found in berries and vegetables. Black elderberry extract, one of the herbal ingredients in FlexAgility MAX, was shown in scientific studies to be more bioavailable – that is, more readily used by the body – than the natural bioflavonoids of other plants. Again, antioxidants help keep the body in optimum health- especially during times of physical stress.

 

Ginger, used for centuries in Ayurvedic medicine, provides strong, natural antioxidant activity. In fact, a recent scientific study found more than 50 separate antioxidants in ginger root.

Of course, there are many components of plants that show strong antioxidant properties. A scientific study comparing flavonoid antioxidant activity and inflammation have shown that rutin was the most effective in reducing the inflammation cascade.

 

Boswellia serrata is a tree found growing in the dry, hilly regions of India. Extracts of boswellia have been used in Ayurvedic practice for centuries. Boswellia also has antioxidant properties that help reduce free radical damage.

Another antioxidant ingredient in FlexAgility MAX, N-acetylcysteine (NAC), even helps the body produce more of its own antioxidants, cysteine and glutathione. In a double-blind, placebo-controlled clinical study, N-acetylcysteine inhibited occasional pain and inflammation due to overuse and attenuated fatigue by 26% compared to controls!

N-acetylcysteine has also been shown in scientific tests to act as an antioxidant, supporting healthy collagen and synovial fluid.

The last ingredient, bromelain, provides the enzymatic pathway used by FlexAgility MAX. Bromelain is a proteolytic enzyme derived from pineapple. Clinical and scientific studies showed benefits from bromelain in reducing pain and inflammation from occasional overuse.

So, there you have it- the triple action of FlexAgility MAX: COX-2 inhibition (and COX-1 sparing), antioxidant benefits, and enzyme support.

 

Q. Is there another product you’d recommend that I use with FlexAgility MAX?

A. One other product I recommend without hesitation is GS-500, a glucosamine sulfate supplement that has been shown to help build and support cartilage. The body’s connective tissue and cartilage include a natural compound called glucosamine. Supplemental glucosamine sulfate is up to 98% absorbable, so more glucosamine reaches the target structures. It has been clinically studied on its effect in building cartilage.

 

 

About Enzymatic Therapy:

 

Like Chris, Enzymatic Therapy is a trailblazer. Since our founding in 1981, we’ve been leading the industry with innovative natural products. After all, in 1993, Enzymatic Therapy introduced glucosamine sulfate, shown to help build and support cartilage, to the United States. Our product, GS-500, is up to 98% absorbable, so more glucosamine reaches the target structures.

In the intervening years, Enzymatic Therapy has been at the frontline of innovation and invention. Many revolutionary precuts, including Saventaro, Cell Forte, Heartburn Free, Petadolex Patented Brain Support, Whole Body Cleanse, Earth’s Promise, Hot Plants for Him and Hot Plants for Her have been introduced by Enzymatic Therapy.

One of the newest products, (and the reason you’re reading this) is FlexAgility MAX. FlexAgility MAX works with the body’s own natural anti-inflammatory pathways to relieve pain and reduce inflammation due to occasional overuse. Our proprietary FlexBend of ingredients, combined with antioxidants and the proteolytic enzyme, bromelain, is unique among natural products.



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Complete Liver Cleanse
TopPreviousNext

Date: April 19, 2007 04:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Complete Liver Cleanse

Complete Liver Cleanse

Technical Data Sheet

 

DESCRIPTION:

The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day.

One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification.

Complete Liver Cleanse:

Includes ingredients for various aspects of liver and gallbladder support:

-Herbal ingredients that support liver and gallbladder health

-Detoxifying ingredients that keep bound toxins from being reabsorbed

-Phytosterols to block cholesterol absorption in the intestines

-Fiber that moves cholesterol and toxins out of the body

-Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan

Fibers

-Simple, two week liver cleanse program

FORMULA:

Each 3 capsules contain:

Calcium (as calcium D-glucarate) 13 mg

Proprietary PuraFiber Blend: 1 mg

Viscofiber Oat B-Gucan Concentrate, phytosterols

(beta sitosterol, campesterol, stigmasterol, brassicasterol,

and other plant sterols), and glucomannan

Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg

One part Milk Thistle Extract, standardized to contain 80%

Silymarin bound to two parts phosphatidylcholine (soy) using

a patented process

Burdock (Arctium lappa) Root Extract 4:1 100 mg

Calcium D-Glucarate 100 mg

Boldo (Peumus boldus) Leaf Extract 2:1 75 mg

Turmeric (Curcuma longa) Rhizome Extract 50 mg

Standardized to contain 90% curcuminoids

Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg

Artichoke (Cynara scolymus) Leaf Extract 30 mg

Standardized to contain 13-18% caffeylquinic

Acids calculated as chlorogenic acid

Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal.

Other ingredients: See label for most current information

Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the U.S., Canada and internationally.

This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by U.S. patent 4,845,123.

HOW DOES IT WORK?

The Liver

Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions.

Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon.

Liver Detoxification

Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide.

The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American.

Herbal Liver Support

One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% silymarin, the plant’s most bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract.

Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification.

Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes.

Phytosome Process

A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, phosphatidylcholine is an important building block of cell membranes.

When milk thistle (or other herbs) are bound with phosphatidylcholine, the phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comparison to the individual herb alone.

To test whether binding an herb with phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system.

Other Herbal Liver Supportive Ingredients

Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and Free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits.

For instance, dandelion root extract supports healthy bile flow from the gallbladder.

Burdock Root:

Burdock is originally native to Europe and Asia, but was introduced to North America, probably during colonial times. The plant is commonly found in the northern United States, and is very recognizable, with large, heart-shaped leaves. It has a long history of traditional use for gastrointestinal support.

Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines.

Boldo:

Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern Europe. The leaves are considered the health supportive part of the plant. This herb has a long history of use in Chile, and became known in Western countries in the late 19th century.

In scientific studies, boldo appears to have strong Free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time.

Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated.

Turmeric:

Turmeric (Curcuma longa) is a perennial shrub native to southern Asia with a long history as both a food ingredient and for health support.

More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function.

In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits.

Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function.

Detoxification

Calcium d-glucarate:

The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile.

However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted.

Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges.

Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body.

Phytosterols

Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder.

Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells.

High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health.

LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day).

One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils.

The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy.

Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines.

The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system.

Fiber and detoxification

Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts.

Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA.

SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health.

Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan.

Konjac:

Konjac, (Amorphophallus Konjac) is a tuber native to Asia, rich in glucomannan polysaccharide. This viscous material is made into a jelly, noodles and other foods. It has been used in Japan for at least a thousand years.

As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid.

Oat beta-glucan:

Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits.

In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial.

Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion.

Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber.

Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit.

RECOMMENDATIONS:

Three capsules in the morning and three capsules at bedtime for 14 days.

LABEL PRECAUTION:

Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.



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Regulating Blood Pressure Naturally
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Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

Regulating Blood Pressure Naturally

 

High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.

In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.

In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.

Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.

 

Blood pressure guidelines from the National Heart, Lung, and Blood Institute.

Category

Systolic (mm/Hg)

Diastolic (mm/Hg)

Result

Normal

Less than 120

And Less than 80

Excellent!

Prehypertension

120-139

Or 80-89

Make changes in eating and drinking habits, get more exercise and lose any extra pounds.

Hypertension

140 or higher

Or 90 or higher

You have high blood pressure. Talk to your healthcare professional on how to control it.

 

Q. What exactly is blood pressure?

A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”

 

Q. What is considered high blood pressure?

A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.

However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.

Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.

To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.

For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.

 

Q. What courses high blood pressure?

A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:

 

Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.

 

Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.

 

Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.

 

Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.

 

Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.

 

Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.

 

Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.

 

As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.

 

Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.

 

Q. What are the blood pressure numbers I should see?

A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.

 

Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?

A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.

However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.

Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.

Let’s take a look at each:

Stevia leaf extract

Supports healthy blood pressure levels according to clinical studies.

Hawthorn extract

Supports the heart and balance sodium and fluid levels.

Olive leaf extract

Scientifically shown to support healthy blood pressure.

Dandelion leaf

Helps reduce fluid retention

Lycopene

Clinically shown to support arteries, circulation and heart health.

 

Stevia:

Stevia (Stevia rebaudiana) originated in South America, and is often used as a sweetener. Glycosides in stevia, particularly stevoside, give the plan its sweet flavor 0 anywhere from 100 to 200 times sweeter than sugar.

The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.

In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.

And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!

Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.

A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.

 

Hawthorn extract:

Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.

The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.

The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.

And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.

Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.

Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.

 

Olive leaf extract:

Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.

But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.

 

Dandelion leaf extract:

Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.

Medicinally, dandelion has been used for centuries, dating back to ancient Greece. Leaves intended for medicinal use are harvested before flowering, to ensure the most nutrients.

They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.

The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.

 

Lycopene:

If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater Free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.

And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.

So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.

 

Q. What can I expect taking this herbal combination?

A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.

When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.

 

Tips for Accurate Blood Pressure Monitoring:

-Relax for about 5 to 10 minutes before measurement.

-If you have just come inside from cold outdoors allow yourself to warm up.

-Remove tight-fitting clothing and jewelry.

-Unless your physician recommends otherwise, use left arm to measure pressure.

-Sit, don’t stand.

-Remain still and do not talk while using the monitor.

 

Q. Are there any side effects?

A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.

 

Conclusion:

High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.

 

In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.



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l-Arginine/l-Citrulline Complex - Supports Peak Performance
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Date: March 06, 2007 02:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: l-Arginine/l-Citrulline Complex - Supports Peak Performance

  • Free-form amino acid combination
  • Arginine supports muscle metabolism and energy
  • Arginine supports heart function and circulation
  • Arginine easily converts into nitric oxide (NO)
  • l-Arginine/l-Citrullinne Complex supports liver detoxification

l-Arginine and l-Citrulline are two amino acids bundled into a single powerful supplement. Both are key intermediates in the Krebs urea cycle, where they participate in the detoxification of ammonia via the production of urea. In addition, any arginine not converted to urea enters general circulation where it is distributed to various tissues and metabolized for other uses such as protein synthesis. l-Arginine is probably best known for its role in cardiovascular health and the formation of nitric oxide (NO). The formation of NO mediates smooth muscle relaxation in the blood vessel wall, and thus reduces the workload of the heart. Many nerve cells also use NO as a signaling molecule. Erectile function, for example, is mediated by the release of NO from the autonomic nerves in the penis. Also, l-Arginine is an important factor in muscle metabolism promoting energy during exercise and increased recovery after a workout.

1 tablet contains:

l-Arginine (as l-Arginine HCI) 750 mg

l-Citrulline 250 mg

Suggested Use: 1 tablet four times daily.



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Neurological Health and CoQ10
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Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from Free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.



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Fruit and Vegetable Lightning drink mixes from Natures Plus
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Date: February 06, 2007 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fruit and Vegetable Lightning drink mixes from Natures Plus

Enjoy the Rainbow – the Color Wheel of Fruits and Vegetables

 

We’ve all heard the statistics, and have probably seen the signs in the produce section of our favorite grocery store: eating 5 servings of fruits and veggies a day is important,

 

Chances are also pretty good that we’ve also seen the newest food pyramid, encouraging Americans to “eat a rainbow of frits and vegetables.” That is, choose from the rich variety of colors for the best all-around health benefits.

 

In this Ask the Doctor, we’re going to look at the unique health components of different colored fruits and vegetables, and why they’re so important. Plus, we’ll learn about supplemental options, like fruit and vegetable drink mixes, for those days when our diets just aren’t that great.

 

Q. What’s the big deal about fruits and vegetables?

A. Well, for the main reason that they are whole foods – created by nature (or at least generations of farming) and are rich in a variety of nutrients. Processed foods can’t match the health benefits of strawberries or broccoli – items that have fiber, vitamins, and enzymes built right in.

 

Q. What does “eating a rainbow” of fruits and vegetables really mean?

A. This is simply an easy way of remembering to get as much color variety in your diet as possible to maximize your intake of a broad range of nutrients. The colors of fruits and vegetables are often a tangible clue to the unique vitamins and other healthy substances they contain. Getting a variety of colors, therefore, means getting a variety of the essential nutrients your body needs to stay healthy and strong.

 

Enjoying the Rainbow: Fruit and Vegetable Benefits:

Color

Source

Nutrients

Benefits

Red

Tomatoes, Berries, Peppers, Radishes

Lycopene, Anthocyanins, Ellagic Acid, Bioflavonoids including Quercetin, and Hesperidin

Reduces risk of prostate cancer; lowers blood pressure; scavenges harmful Free-radicals; reduces tumor growth; reduces LDL cholesterol levels and supports joint tissue in cases of rheumatoid arthritis

Orange/ Yellow

Carrots, Yams, Squash, Papaya

Beta-carotene, Zeaxanthin, Flavonoids, Lycopene, Vitamin C, Potassium

Reduces age-related macular degeneration; lowers LDL (bad) cholesterol; fights harmful free radicals; reduces risk of prostate cancer, lowers blood pressure; promotes collagen formation and healthy joints; encourages alkaline balance and works with magnesium and calcium to build healthy bones

White

Mushrooms, White Tea, Flaxseed/ Pumpkin

Beta-glucan, EGCG (epigallocatechin gallate), SDG (secoisolariciresinol digulcoside), lignans

Provides powerful immune boosting activity; activates natural-killer cells, B-cells and T-cells; may reduce risk of colon, breast and prostate cancers; boosts immune-supporting T-cell activity; balances hormone levels and may reduce risk of hormone-related cancers

Green

Wheat Grass, Barley Grass, Oat Grass, Kale, Spinach, Cabbage, Alfalfa Sprouts, Mustard Greens, Collard Greens

Chlorophyll, Fiber, Lutein, Zeaxanthin, Calcium, Folate, Glucoraphanin, Vitamin C, Calcium, Beta-Carotene

Reduces cancer risks; lowers blood pressure; normalizes digestion time; supports retinal health and reduces risk of cataracts; builds and maintains bone matrix; fights harmful Free-radicals; boosts immune system activity; supports vision and lowers LDL cholesterol levels

Purple/ Blue

Blueberries, Pomegranates, Grapes, Elderberries, Eggplant, Prunes

Anthocyanins, Lutein, Zeaxanthin, Resveratrol, Vitamin C, Fiber, Flavonoids, ellagic acid, quercetin

May protect brain cells against Alzheimer’s and other oxidative-related diseases; supports retinal health; lowers LDL cholesterol and prevents LDL oxidation; boosts immune system activity and supports healthy collagen and joint tissue; supports healthy digestion; improves calcium and other mineral absorption; fights inflammation; reduces tumor growth; acts as an anticarcinogen in the digestive tract, limits the activity of cancer cells –depriving them of fuel; helps the body fight allergens

 

Q. Can you tell me a little more about the healthy components of fruits and vegetables?

Let’s take a look at some of the most well-studied and important nutrients:

 

Quercetin is found in apples, onions and citrus fruits (also is hawthorn and other berries and apple-related fruits usually used in traditional herbal remedies and modern supplements). It prevents LSL cholesterol oxidation and helps the body cope with allergens and other lung and breathing problems.

 

Clinical studies show that quercetin’s main points of absorption in the body appear to be in the small intestine – about 50%. The rest – at least 47% is metabolized by the colonic micro flora – the beneficial bacteria such as Lactobacillus acidophilus and Bifidobacterium longum. You may consider adding these beneficial bacteria (found in yogurt) either through the diet or a supplemental form.

 

Ellagic Acid is a component of ellagitannins – dietary polyphenols with antioxidant (and possibly anticancer) properties. Polyphenols are the basic building blocks of many plant-based antioxidants. More complex phenolic compounds, such as flavonoids are created from these molecules.

 

Ellagic acid is found in many fruits and foods, namely raspberries, strawberries, pomegranates, and walnuts. Clinical studies suggest that ellagitannins and ellagic acid act as antioxidants and anticarcinogens in the gastrointestinal tract.

 

Ellagitannins are durable antioxidants, and happily, they do not appear to be diminished by processing, like freezing. This means the benefits are still strong, even in frozen packs of raspberries or strawberries, or some of the better multi-ingredient supplement drink mixes.

 

In scientific studies, ellagic acid also showed an anti-proliferative effect on cancer cells, decreasing their ATP (adenosine triphosphate) production. ATP is the molecule that provides the primary energy source for the cells in our bodies. In a sense, ellagic acid seems to deprive cancer cells of their fuel.

 

Beta-Carotene: Probably the best-known of the carotenoids, beta-carotene is converted by the body into vitamin A. Many vegetables, especially orange and yellow varieties, are rich in this nutrient. Think summer squash, yams and of course, carrots.

 

Beta-carotene has long been associated with better eyesight, but it has other benefits, too. In a scientific study, beta-carotene decreased cholesterol levels in the liver by 44% and reduces liver triglycerides by 40%.

 

Lycopene is a carotenoid mostly found in tomatoes, but also in smaller amounts in watermelon and other fruits. Clinical studies have shown that lycopene consumption may decrease the risk of prostate cancer. In fact, high intakes of lycopene are associated with a 30% to 40% reduced risk. And, as good as beta-carotene is, its cousin, lycopene, seems to be an even stronger nutrient, protecting not just against prostate cancer, but heart disease as well.

 

Lutein is found in many fruits and vegetables, including blueberries and members of the squash family. Lutein is important for healthy eyes, and in fact it is found in high concentrations naturally in the macular region of the retina – where we see fine detail. It is one of the only carotenoids, along with its close sibling zeaxanthin, that is found in the macula and lens of the eye.

 

Lutein also supports your heart, too. In a scientific study, lutein reduced atherosclerotic lesion size by 43%. In other words, high intakes of lutein may actually help prevent coronary artery disease!

 

Interestingly, as is the case with lycopene, cooking or processing foods with lutein may actually make it more easily absorbed.

 

In clinical studies, men with high intakes of lutein (and its close cousin, zeaxanthin, found in broccoli and spinach) had a 19% lower risk of cataract, and women had a 22% decreased risk, compared to those whose lutein intakes were much lower.

 

Vitamin C: One of the best-known nutrients out there, vitamin C keeps our immune system strong; speeds wound healing, and promote strong muscles and joints. A Free-radical fighter, vitamin C prevents oxidative damage to tissues, builds strength in collagen and connective tissue, and even reduces joint pain.

 

Sources of vitamin C are scattered throughout the spectrum of fruits and vegetables. Oranges and other citrus are the most commonly associated with vitamin C, but it also is present in tomatoes, and to a lesser extent in berries and cherries.

 

Potassium: Most Americans are deficient in potassium. For the most part, it’s hard to get too much of this valuable mineral. Potassium does great things for our hearts. Higher intakes of dietary potassium from fruits and vegetables have been found in clinical research to lower blood pressure in only 4 weeks.

 

Many researchers believe that the typical American diet has led to a state of chronic, low-grade acidosis – too much acid in the body. Potassium helps change pH balance to a more alkaline environment in the body and increases bone density.

 

This was proven in the long-running Framingham Heart Study which showed that dietary potassium, (along with magnesium and fruit and vegetable intake) provided greater bone density in older individuals.

 

Fiber is another food component many just don’t get enough of – especially if they’re eating a “typical American diet.” Fruits, vegetables and whole grains are excellent sources of fiber. However, fiber from a good fruits and vegetable drink mix should be derived from inulin and chicory root. This soluble fiber source not only adds to the overall amount of fiber you need (25 to 38 grams a day), but also provides a nice “nesting ground” for the beneficial bacteria that populate the intestines. And, even though some fiber has a bad rap for inhibiting mineral absorption, inulin and chicory root are “bone building” fibers – they actually help the body absorb calcium.

 

Flavonoids are an overarching term that encompasses flavonols, anthocyanidins, and flavones, isoflavones, proanthocyanidins, Quercetin and more. They are almost everywhere: in fruits, vegetables, grains, herbs, nuts and seeds – even in the coffee, wine and tea we drink. Flavonoids are responsible for the colors in the skins of fruits and the leaves of trees and other plants.

 

Flavonoids have many health benefits. They can help stop the growth of tumor cells and are potent antioxidants. Additionally, flavonoids have also been studied for their ability to reduce inflammation.

 

Anthocyanins: High on the list of important “visible” nutrients are anthocyanins. They color fruits and vegetables blue and red.

 

Anthocyanins are members of this extended family of nutmeats, the flavonoids. Typically found in high amounts in berries, anthocyanins are readily absorbed in the stomach and small intestine.

 

As antioxidants, anthocyanins dive deep into cell membranes, protecting them from damage. IT may be one reason why the anthocyanins from blueberries are considered such an important component in battling neuronal decline, like Alzheimer’s. Blackberries, raspberries, and strawberries are also excellent sources of this flavonoids group.

 

SDG lignans, (short for secoisolariciresinol diglucoside) are polyphenolic components of flaxseed, pumpkin and other herbal sources. Much of the recent research surrounding lignans has focused on flaxseed. In scientific and clinical studies, lignans from flaxseed support hormonal balance and may have cancer-preventing abilities. In fact, in one study, flaxseed lignans reduced metastatic lung tumor by 82% compared to controls.

 

The lignans in pumpkin seed, also considered a major source, target 5-alpha reductase activity.

 

This enzyme catalyzes the conversion of testosterone into the more potent dihydrotestosterone (DHT). DHT, like testosterone, is a steroid hormone or androgen. Androgens are responsible for the development and maintenance of masculine sex characteristics in both men and women. Excess levels of DHT can cause serious problems with prostate or bladder health. That’s why modulation of the 5-alpha reductase enzyme is so important – it helps maintain healthy testosterone and DHT levels. By balancing the levels of these key hormones, pumpkin seed lignans provide protection for prostate and bladder cells.

 

In addition, pumpkin seed has been shown to modulate the enzyme aromatase. Aromatase is present in the estrogen-producing cells of the adrenal glands, ovaries, testicles, adipose tissue, and brain. Aromatase converts testosterone, an androgen, into estradiol, and estrogen.

 

Inhibition of the aromatase conversion can help maintain a balance of healthy testosterone levels in women, which has been shown to strengthen pelvic muscles and reduce incidence of incontinence.

 

In fact, a clinical study, involving a pumpkin extract in conjunction with soy, resulted in significant support for bladder health. After two weeks of supplementation, 23 of the 39 postmenopausal women enrolled in the study showed great improvement in urinary frequency and sleep. By the end of the six week study, 74.4 percent of participants found pumpkin extract safely and significantly improved “nocturnia,” that is, the need to urinate frequently at night. For individuals with 2 to 4 episodes of nocturnia prior to the stud, and 81.8% improvement was seen – also showing great improvement in sleep quality. After all, if you don’t have to wake up every couple of hours to go to the bathroom you’re bound to get better sleep.

 

Beta glucan: Mushrooms are intense immune-boosting powerhouses due to their beta-glucan content. Three well-studied power-house mushrooms that contribute beta glucan to the diet include maitake, reishi and shiitake.

 

The most significant constituents of mushrooms are long chain polysaccharides (molecules formed from many sugar units) known as beta-glucan. These huge molecules act as immunoregualtors in the human body, helping to stabilize and balance the immune system.

 

This includes specific support of white blood cells, or lymphocytes, the primary cells of the immune system. Lymphocytes fall broadly into three categories: T cells, B cells, and natural killer (NK) cells.

 

In one clinical study, 165 patients with various types of advanced cancer were given maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, and 62% of lung cancer patients. Plus, when maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.

 

In another clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.

 

And, in a scientific study of human breast cancer and myeloma cancer and myeloma cancer cell lines, shiitake compounds provided a 51% antiproliferative effect on the cells – inducing “apoptosis’ – the programmed cell death that should occur naturally.

 

While beta-glucan are distributed throughout the mushroom body, the beta-glucan concentrations are significantly higher in the mycelium – the interwoven fibers or filaments that make up the “feeding structure” of the mushroom.

 

Bioflavonoids are commonly found in bright yellow citrus fruits, including lemons, limes and oranges. They are responsible for the bright pigment found in the skin of the fruit, and are considered a “companion” to vitamin C, seeming to extend the value of the nutrient within the body.

 

Hesperidin is just one of the valuable bioflavonoids found in citrus. Hesperidin appears to lower cholesterol levels, as well as support joint collagen in examples of rheumatoid arthritis.

 

Epigallocatechin gallate (EGCG):

Polyphenols, most notably EGCG, or epigallocatechin gallate, are well-studied and powerful components of tea. EGCG has been shown to reduce colon and breast cancer risk. Green tea also boosts the immune system and encourages T-cell formation – part of the front-line defense of our bodies against sickness and disease.

 

Q. I’ve been seeing articles about fruits, vegetables and supplements touting “high ORAC value.” What does this mean?

ORAC is an acronym for Oxygen Radical Absorption Capacity, and is simply a measurement of antioxidant activity of nutrients. Oxygen radicals, or free radicals, are unstable molecules. They grab electrons from other cells to use for themselves, and in the process can damage them. It is believed that free radical activity plays a role in the development of many diseases such as heart disease and cancer, and also plays a role in aging.

 

Antioxidants help prevent this damage by “loaning out” extra electrons to stabilize free radicals/ Consider any fruit or vegetable with a high ORAC rating as having a lot of “antioxidant power.”

 

I know I should eat more fruits and vegetables, but it just seems so hard to get five servings a day.

The number one excuse I hear for not buying frits and veggies is that “fruits and vegetables are too expensive.” But are they really? Certainly, fresh foods that aren’t in season and have to be shipped a distance can be a bit pricey. If anyone added up how much spend on fast food, or prepackaged or processed snacks, it would probably be shocking.

 

Luckily, there are many ways to get your “Daily 5”. For instance, frozen fruits and veggies retain much of their nutrient profile. They can be an excellent alternative when certain foods are out of season. So too, are fruit and vegetable drink mixes – excellent supplemental sources of some of the nutrients our bodies need most.

 

More recently, the American Institute of Cancer Research discovered a reason many adults don’t eat their vegetables is – I’m not making this up – “a fear of flatulence.”

 

Of course, for people not accustomed to the fiber in fruits and veggies, there is some reason to think it’ll increase gas. When cell walls break down, and fiber passes through the system, it can create flatulence. Folks who eat fruits and vegetables every day generally don’t have this problem. Their systems are already accustomed to it.

 

For those just starting out on a better diet, however, start slowly – it helps your body adapt. Cooking vegetables can help, too, because it begins breaking down the cell walls early on.

 

One thing is certain, however. The “Typical American Diet” and good health are mutually exclusive. The increase in type 2 diabetes, heart disease, high cholesterol, and hypertension all point to the abuse our bodies suffer by eating diets high in fatty meats, processed sugars, and refined grains.

 

Q. Can I just drink fruit and vegetables drinks in place of 5 servings of fruits and vegetables?

Green drinks and fruit and vegetable drink mixes aren’t meant to replace whole foods, but they can be an excellent substitute when you’re rushed or traveling or just trying to fill everyday nutritional gaps. Their whole food ingredients absorb very easily and gently in the gut, and many of these drink mixes contain healthy doses of fiber, too.

 

Green drink mixes and food-based drink mixes combine many colorful fruits and vegetables and sometimes grasses in a healthy, mixable supplement assortment. While there have been many advancements in the field of green drinks, there are only a few that take the primary reason we eat into consideration: taste!

 

Happily, there are some companies out there with great-tasting drink mixes that also formulate based on the color concept, ensuring you get the broadest assortment of nutrients from a full range of fruit and vegetable colors to promote optimal health.

 

High-quality fruit and vegetable drink mixes offer the best from nature’s color wheel in a convenient and great-tasting supplement. So, the next tie you feel like taking a coffee break – try a fruit and veggie break instead. Your body and spirit will thank you.

 

 



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What are Amino Acids?
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Date: September 07, 2006 12:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are Amino Acids?

Amino acids are the smallest molecules that comprise protein, commonly referred to as the “building blocks of life” – they build all body and tissue protein. Seventy-five percent of the body’s solid weight is made up of proteins and their constituent amino acids. Unable to be efficiently stored in the body, amino acid reserves must be re-supplied continuously.

Twenty three amino acids support the growth, repair and maintenance of about 1600 different types of proteins in the human body, including muscles, connective tissues, hormones, enzymes, antibodies, hair, skin, nails and blood.



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HDL Booster - Boost your good cholesterol
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Date: March 16, 2006 12:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HDL Booster - Boost your good cholesterol

 

                                      

 

 

HDL BOOSTER

(Product No. 02922)

 

 

 

DESCRIPTION:

 

HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*  

 

HDL Booster:

 

·         Formulated by Dr. Dennis Goodman, Chief of Cardiology at Scripps Memorial Hospital

·         Clinically studied to increase good cholesterol levels up to 23%*1

·         All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association

·         Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2

 

STRUCTURE/FUNCTION:

 

HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*  

 

FORMULA:

 

Two tablets (one serving) contain:

 

Vitamin C (ascorbic acid)                                                          148 mg

Vitamin E (as natural mixed tocopherols)                                    35 IU

Niacin (as niacinamide)                                                              21 mg

Vitamin B6 (as pyridoxine HCl)                                                  3 mg

Folic Acid                                                                                 301 mcg

Vitamin B12 (as cyanocobalamin)                                              20 mcg

Magnesium (from magnesium amino acid chelate)                       10 mg

Selenium (as L-selenomethionine)                                               49 mcg

Proprietary Blend                                                                      388 mg

   hawthorn (Crategus oxyacantha) berry extract,         

   taurine, garlic (Allium sativum) bulb, grape seed (Vitis

   vinifera) extract, grape skin (Vitis vinifera) extract,

   N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine

   max) isoflavones, tocotrienols

L-Arginine (as L-arginine HCl)                                                  153 mg

L-Carnitine (as L-carnitine L-tartrate)                                        51 mg

Coenzyme Q10 (CoQ10)(ubiquinone 10)                         25 mg

Policosanol                                                                                7 mg

 

Other ingredients: See label for most current information.

 

Contains no: sugar, salt, yeast, wheat, gluten,  corn, dairy products, artificial coloring, artificial flavoring, or preservatives.  This product contains natural ingredients; color variations are normal. 

 

INTRODUCTION:

 

Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5

 

Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4

 

Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4

 

Types of Cholesterol

 

Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5

 

LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6

 

Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7

 

The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7  

 

HOW IT WORKS:

 

HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9

 

Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at Scripps Memorial Hospital to evaluate the effects of a proprietary supplement on lipid profiles. The dietary supplement, which mirrors HDL Booster and contains a combination of antioxidants, B-vitamins, amino acids, and botanical extracts, was developed by Dr. Goodman, the leading cardiologist at Scripps. The trial involved 50 people, who were evaluated prior to the study, then again at three and six months. After three months of supplementation, good cholesterol levels increased in all groups.* The changes were more pronounced at the six-month time point, where good cholesterol rose up to 23 percent and levels of HDL-2 (the best cholesterol) increased 50 percent in one subset of participants (HDL <40 mg/dL).*1 Additionally, the supplement also helped maintain healthy triglycerides levels that were already within the normal ranges.* Decreases in homocysteine, an amino acid found in the blood that plays a role in cardiovascular health, were observed as well.*1,10

 

The following chart summarizes the benefits of each of the ingredients in HDL Booster:

 

Ingredient

Benefit

Vitamin C

An antioxidant clinically shown to support the health of the cardiovascular system and increase HDL-2 cholesterol levels.*11,12 An important factor in many metabolic reactions, including the conversion of cholesterol to bile salts and the formation of healthy connective tissue. Vitamin C provides protection for the inner lining of the arteries.*13,14

Vitamin E

Another powerful antioxidant, which inhibits the oxidation of low density lipids by inactivating free radicals.* Thought to inhibit the breakdown of certain fatty acids that help form cell structures, especially membranes13

Also supports healthy cholesterol levels already within the normal range.*15,16

Niacin

In lipid metabolism, supports normal cholesterol production and metabolism to help retain healthy cholesterol levels that are already within normal limits.*13 Increases good cholesterol levels, particularly HDL-2 (the best cholesterol).*17 Through peripheral vasodilatation, niacin also supports the retention of healthy blood pressure that is already within the normal range.*13

Vitamin B6

An essential coenzyme for normal amino acid metabolism. In particular, vitamin B6 is necessary for the breakdown of homocysteine, an amino acid that plays a supporting role in cardiovascular health.* Also involved in the production of circulating antibodies.13 High levels of circulating vitamin B6 have been associated with reduced levels of C-reactive protein, another important indicator of heart health.*18

Folic Acid        

Another homocysteine lowering agent, folic acid is essential for the formation of red and white blood cells and involved in the synthesis of certain amino acids.*13

Vitamin B12

A ubiquitous coenzyme necessary for DNA synthesis. Also lowers homocysteine levels.*13

Magnesium

Increases HDL levels, supporting a healthy lipid profile, and helps maintain healthy blood pressure already within the normal limits.*19 Magnesium is a constituent of many coenzymes and is required for normal functioning of muscle and nervous tissue.20

Selenium

An essential trace mineral with powerful antioxidant capabilities.*20 Research has revealed that selenium supports cardiovascular function.*21

L-Arginine

An important amino acid and precursor to nitric oxide (NO), which is important for the health of the cardiovascular, immune, and nervous systems.*22 In clinical study, an L-arginine-enriched diet increased good cholesterol levels.*23

L-Carnitine      

A naturally occurring hydrophilic amino acid derivative, both produced in the kidneys and liver and derived from dietary sources. Along with coenzyme Q10, L-carnitine is a key factor in metabolism, supporting the production of cellular energy.*24 Also shown to increase good cholesterol (HDL) levels.*25 L-carnitine supports healthy blood flow.*26

Coenzyme Q10 (CoQ10)

A fat-soluble nutrient present in the mitochondria of virtually all cells, CoQ10 is an essential factor for cellular energy production.27 Also a powerful free radical scavenger, clinically shown support arterial health.*27,28

Supplementation significantly improves good cholesterol levels.*29 Additionally, CoQ10 supports healthy heart contractility and circulation.*

Policosanol

A unique mixture of essential alcohols, including octacosanol, tetracosanol, hexacosanol and triacontanol, derived from sugar cane.30 In a clinical study, supplementation resulted in a 14 percent increase in HDL cholesterol over an 8-week period.*31

Hawthorn Berry Extract

Helps retain healthy cholesterol levels already within the normal range.* Supports the muscle strength of the heart, helping to maintain healthy heart rhythm, contractility, and vascular circulation.*32 A source of antioxidant constituents that protect against oxidative damage.* Supports the health of veins and arteries.*33,34 Also helps maintain healthy blood pressure levels already within the normal ranges.*

Taurine

An essential amino acid, present in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. Possesses both antioxidant and membrane-supportive properties.*35 Helps maintain a healthy lipid profile by increasing good (HDL) cholesterol levels.*36,37

Garlic Bulb

A powerful antioxidant that possesses wide-ranging cardiovascular health benefits.*38 Clinically shown to increase good cholesterol levels, particularly HDL-2 cholesterol.* 39

Grape Seed Extract

A source of Free-radical scavenging phytonutrients, known as polyphenols.* Promotes healthy circulation.* Also supports cardiovascular health by increasing HDL cholesterol levels*40,41

N-Acetyl-L-Cysteine (NAC)

A derivative of the amino acid, cysteine, NAC is a key intermediary in the conversion of cysteine into glutathione, one of the body’s primary cellular antioxidants.* Supports the health of the cardiovascular and immune systems.* Also shown to significantly increase in HDL cholesterol.*42

Alpha Lipoic Acid (ALA)

An antioxidant and vital cofactor necessary for the production of cellular energy, ALA helps recycle other important antioxidants, including vitamins C and E, CoQ10, and glutathione. Also helps maintain healthy blood flow and healthy heart contraction.*43

Soy Isoflavones

Provide antioxidant protection, supporting cardiovascular and immune system health.* Soy protein-enriched diet has been shown

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High Absorption CoQ10
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Date: February 13, 2006 05:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: High Absorption CoQ10

The human heart beats more than two and a half billion times in an average lifetime. The energy required for this miracle of nature is enormous, and maintaining heart tissue energy levels is essential. A vitamin-like nutrient found in the human body, Coenzyme Q10 or CoQ10 supports heart function. Without adequate CoQ10, cells become energy-deficient. When nourished with optimal levels of CoQ10, your body tissues, including the liver, nerves and muscles function optimally. With its high energy requirements, the heart needs to be supplied with CoQ10 at all times. Numerous clinical studies have shown significant improvements in heart function with oral administration of CoQ10. Immune cells need large amounts of energy, and CoQ10 helps make it available. A versatile antioxidant, it stabilizes membranes and protects them from Free-radical damage. A fat-soluble nutrient, CoQ10 is difficult to absorb, so we’ve added Bioperine. Preliminary Trails on humans have shown significant increases in absorption of Bioperine-enhanced nutrients. High absorption CoQ10, a pharmaceutical grade supplement, is now available in three different forms: 30mg/60 caps; 100mg/30 caps; and 100mg/60 caps. High Absorption CoQ10 with bioperine


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Benefits of Best Alpha Lipoic 35!
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Date: February 12, 2006 03:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Best Alpha Lipoic 35!

Benefits

Supports the Body’s Defense Against Free Radicals*

Recycles Antioxidant Nutrients such as Vitamin C and Vitamin E*
Helps Maintain a Healthy Blood Sugar Level when used as part of the diet*

Alpha-lipoic Acid––the "Ideal Antioxidant"
The antioxidant potential of a substance is based on a number of criteria, including:
1) Ability to quench specific Free-radicals.
2) Ability to bind or "chelate" metal ions that can generate free radicals.
3) Supports function of other antioxidants.
4) Absorption/bioavailability.
5) Concentration in tissues, cells and extra cellular fluids.
6) Ability to function as an antioxidant in fatty and watery environments.


The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.

As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3
1) ALA is easily absorbed when consumed orally.
2) ALA is readily converted to DHLA in various tissues.
3) As a pair, ALA and DHLA neutralize superoxide, hydroxyl, peroxyl, and hypochlorus radicals.
4) ALA and DHLA form stable complexes with metal ions such as iron, manganese, copper and zinc ions.
5) ALA and DHLA scavenge free radicals in fatty environments and watery environments.
6) DHLA recycles other important antioxidants.


DHLA-regenerates vitamin C, vitamin E and glutathione

Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants.

DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7

Alpha-lipoic Acid and Blood Sugar

Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10



Safety

Suggested Adult Use: One to six capsules daily with food.

Alpha-lipoic acid is considered safe, and no adverse effects have been seen with long-term supplementation.1

Scientific References
1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50.
2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63.
3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31.
4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21.
5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561.
6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637.
7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87.
8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4.
9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14.
10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804.


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Erythritol Sweetener Fact Sheet
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Date: December 17, 2005 10:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Erythritol Sweetener Fact Sheet

Erythritol Sweetener Fact Sheet

Neil E. Levin, CCN, DANLA 11/4/04

LIKELY USERS: People on low-carb diets, People on calorie-restricted diets, People on restricted blood sugar diets, People concerned about dental caries (cavities).

KEY INGREDIENT(S): Erythritol crystals

MAIN PRODUCT FEATURES

Physical properties:

A transparent white brilliant appearance, Free-flowing crystalline powder. A very clean, sweet taste profile, similar to sucrose with no significant after-taste. The dry form exhibits a strong cooling effect. Has a similar look and taste to sugar. Erythritol will brown like sugar. Sweetness: Only about 70% as sweet as sugar; one teaspoon is equivalent to one teaspoon of sugar in baking measurements.

Fewer calories than white sugar: less than 0.2 calories per gram, only 5% as much as sucrose A sugar alcohol that is not a source of “impact carbs” that raise blood sugar Suitable for low-carb (carbohydrate-restricted) diets “Zero” glycemic index sweetener, also rated “zero” on the insulinemic index Does not affect serum glucose or insulin levels. Will not promote tooth decay Laxative effects are unlikely, unlike some other sugar alcohols OTHER IMPORTANT ISSUES: No artificial sweeteners, designated as GRAS (generally regarded as safe) status by the FDA. Pesticides: Absent (at ppm level)

AMOUNT TO USE: One or more teaspoons, as desired. 1.5 teaspoon has about the sweetness of a teaspoon of sugar.

SYNERGISTS: Flavor mixes well with other sweeteners, can be blended with them to “cut” them and improve their flavor.

CAUTIONS: Large doses are unlikely to have a laxative effect, unlike most other sugar alcohols. Doses of 1 gram per kilogram (2.2#) of body weight, equivalent to 68 grams per 150-pound adult, are typically well tolerated by adults. No other known cautions.



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Tru-E Bio Complex
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Date: December 08, 2005 04:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Tru-E Bio Complex

Tru-E Bio Complex TM

Neil E. Levin, CCN, DANLA 7/27/05

LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed

MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements.

NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32

Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32

This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7

Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols.

All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU).

Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet.

Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market.

We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32

Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23

SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal.

SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds

CAUTIONS: None.

SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

REFERENCES:

1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
2. Schneider C (2005) Chemistry and biology of vitamin E. Mol Nutr Food Res 49(1):7-30.
3. Pfluger P, Kluth D, Landes N, Bumke-Vogt C, Brigelius-Flohe R (2004) Vitamin E: underestimated as an antioxidant. Redox Rep 9(5):249-254.
4. Liu M, Wallin R, Saldeen (2002) Effect of mixed tocopherols on ecNOS, SOD, and PKC in leukocytes in human subjects. Nutr Res 22:1253-1263.
5. Saldeen T, Li D, Mehta JL (1999) Differential Effects of a- and g-Tocopherol on Low-Density Lipoprotein Oxidation, Superoxide Activity, Platelet Aggregation and Arterial Thrombogenesis. J Am Coll Cardiol 34:1208-1215.
6. "Packer L, Valacchi G. (2002) Antioxidants and the response of skin to oxidative stress: vitamin E as a key indicator. Skin Pharmacol Appl Skin Physiol 15(5):282-90."
7. Sen CK, Khanna S, Roy S. (2004) Tocotrienol: the natural vitamin E to defend the nervous system? Ann N Y Acad Sci 1031:127-42.
8. Dial S, Eitenmiller RR. 1995. Tocopherols and tocotrienols in key foods in the U.S. diet. In: Ong ASH, Niki E, Packer L, eds. Nutrition, Lipids, Health, and Disease. Champaign, IL: AOCS Press. Pp. 327–342.
9. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000). Institute of Medicine
10. JASPREET K.C. AHUJA, JOSEPH D. GOLDMAN, and ALANNA J. MOSHFEGH. Current Status of Vitamin E Nutriture. Ann NY Acad Sci 2004 1031: 387-390.
11. Bauernfeind, J. Tocopherols in Foods. In: Vitamin E: A Comprehensive Treatise. Marcel Dekker, Inc., New York and Basel, pp. 99-167, 1980.
12. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
13. Weber, P., Bendich, A. and Machlin, L.J. Vitamin E and Human Health: Rationale for Determining Recommended Intake Levels. Nutrition 13:450-460, 1997.
14. Acuff RV et al. Am. J. Clin. Nutr. 1998;67:459-64
15. Acuff RV et al, Am. J. Clin. Nutr. 1994, 60:397-402
16. Behrens, W.A. and Madere, R. Tissue Discrimination between Dietary RRR-Alpha- and All-Rac-Alpha-Tocopherols in Rats. J. Nutr. 121:454-459, 1991.
17. Burton G et al, Am. J. Clin. Nutr. 1998,67:669-84
18. Ferslew, K.E., Acuff, R.V., Daigneault, E.A., Woolley, T.W. and Stanton, P.E. Pharmacokinetics and Bioavailability of the RRR and All Racemic Stereoisomers of Alpha-Tocopherol in Humans after Single Oral Administration. J. Clin. Pharmacol. 33:84-88, 1993.
19. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
20. Ogihara, T., Nishida, Y., Miki, M. and Mino, M. Comparative Changes in Plasma and RBC Alpha-Tocopherol after Administration of dl-Alpha-Tocopheryl Acetate and d-Alpha-Tocopherol. J. Nutr. Sci. Vitaminol. 31:169-177, 1985.
21. Traber M et al, FEBS Letters 1998,437:145-148
22. Traber MG, et al. J Lipid Res. 1990,31(4):675-85
23. Weiser, H. and Vecchi, M. Stereoisomers of Alpha-Tocopheryl Acetate. II. Biopotencies of All Eight Stereoisomers, Individually or in Mixtures, as Determined by Rat Resorption-Gestation Tests. Internat. J. Vit. Nutr. Res. 52:351-370, 1982.
24. Polidori MC, Mecocci P, Stahl W, et al. Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab Res Rev 2000;16:15–9.
25. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, and Mordan LJ. gamma-Tocopherol Detoxification of Nitrogen Dioxide: Superiority to alpha-Tocopherol. PNAS 1993; 90: 1771-1775.
26. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 Feb;81(2):508-14. PMID: 15699242
27. Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M, Miyazawa T. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317
28. Kline K, Yu w, Sander BG, et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. (1999), Nutr Cancer, 33 : pp : 26 – 32
29. The Chicago Health and Aging Project, Martha Clare Morris, Denis A Evans, Christine C Tangney, Julia L Bienias, Robert S Wilson, Neelum T Aggarwal and Paul A Scherr. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. American Journal of Clinical Nutrition, Vol. 81, No. 2, 508-514, February 2005
30. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388
31. Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem. 1992 Oct 2;35(20):3595-606. PMID: 1433170
32. Soelaiman IN, Ahmad NS, Khalid BA. Palm oil tocotrienol mixture is better than alpha-tocopherol acetate in protecting bones against Free-radical induced elevation of bone-resorbing cytokines. Asia Pac J Clin Nutr. 2004 Aug;13(Suppl):



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Triphala Fact Sheet
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Date: December 08, 2005 04:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Triphala Fact Sheet

Triphala Fact Sheet

Neil E. Levin, CCN, DANLA 6/30/05

LIKELY USES: Antioxidant Colon Cleansing, Detoxifying, Digestive, Liver and bile health

KEY INGREDIENTS: Triphala 500 mg, in a combination of fruit powders and extracts

MAIN PRODUCT FEATURES: Triphala is a combination of three fruits (Harada, Amla, and Behada) that has been used in Ayurvedic herbalism for thousands of years. Triphala's historical use as a digestive cleanser and tonifier has been backed up with numerous modern scientific studies demonstrating the positive effects of its component herbs on the gastrointestinal tract. In addition, Triphala has been shown to be a potent antioxidant, protecting cells against the damaging effects of free radicals. May help to dispel worms. Mild-acting internal cleansing; supports liver and gastrointestinal function

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW offers the first - and only - Triphala supplement to combine the fruit powders (400 mg) with the extracts (100 mg) of the fruits (doses given per tablet, there are three tablets per serving). Authorities like Dr. Andrew Weil consider Triphala to be a superior bowel tonic, rather than a laxative, with its benefits increasing over time. Laxatives typically are habit-forming and do not enhance normal body elimination of wastes; this is not the case with (moderate doses of) Triphala. This formula is suitable for vegetarians and is offered in tablet form.

SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every three tablets provide 1,200 mg. (1.2 gram) Triphala powder and 300 mg. (0.30 gram) Triphala extract. Both the powder and the extract provide the three fruits in equal ratios, by weight. Take one to three servings per day, between meals.

COMPLEMENTARY PRODUCTS: Fiber sources (psyllium, pectin, etc.), Detox Support, Plant Enzymes, Virgin Coconut Oil, Dr. Verghese Liver Formula, Bentonite Powder, Probiotics (GR-8 Dophilus, 4x6 Acidophilus, etc.), Electrolytes (minerals) CAUTIONS: none

PRODUCT SPECIFIC: Contraindicated during pregnancy and lactation; avoid during menstruation; not appropriate for the very young or very old or the convalescent.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems.

Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES: Abraham S, Kumar MS, Sehgal PK, Nitish S, Jayakumar ND. Evaluation of the inhibitory effect of triphala on PMN-type matrix metalloproteinase (MMP-9). J Periodontol. 2005 Apr;76(4):497-502. PMID: 15857087 Al-Rehaily AJ, Al-Howiriny TA, Al-sohaiani MO, Rafatullah S. (2002) Gastroprotective effects of 'Amla" Emblica officinalis on in vivo test models in rats. Phytomedicine 9(6):515-522.

Arora S, Kaur K, Kaur S. Indian medicinal plants as a reservoir of protective phytochemicals. Teratog Carcinog Mutagen. 2003;Suppl 1:295-300. PMID: 12616620 Jagetia GC, Baliga MS, Malagi KJ, Sethukumar Kamath M. The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation. Phytomedicine. 2002 Mar;9(2):99-108. PMID: 11995956 Jagetia GC, Malagi KJ, Baliga MS, Venkatesh P, Veruva RR (2003) Triphala, an Ayurvedic Rasayana Drug, Protects Mice Against Radiation-Induced Lethality by Free-Radical Scavenging. J Alt Complement Med 10(6):971-978. Jagetia GC, Rao Sk,, Baliga MS, Babu K (2004) The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary study. Phytother Res 18(7):561-565.

Kaur S, Michael H, Arora S, Harkonen PL, Kumar S. The in vitro cytotoxic and apoptotic activity of Triphala--an Indian herbal drug. J Ethnopharmacol. 2005 Feb 10;97(1):15-20. Epub 2004 Dec 25. PMID: 15652269 Kaur S, Arora S, Kaur K, Kumar S. The in vitro antimutagenic activity of Triphala--an Indian herbal drug. Food Chem Toxicol. 2002 Apr;40(4):527-34. PMID: 11893411 Sabu MC, Kuttan R (2002) Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol 81:155-160. Sairam K, Rao CV, Dora M, Babu K, Kumar V, Agrawal VK, Goel RK (2002) Antiulcerogenic effect of methanolic extract of Emblica Officinals: an experimental study. J Ethnopharmacol 82:1-9. Sandhya T, Lathika KM, Pandey BN, Mishra KP. Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drug. Cancer Lett. 2005 May 14; [Epub ahead of print] PMID: 15899544 Tamhane MD, Thorat SP, Rege NN, Dahanukar SA (1997) Effect of oral administration of Terminalia chebula on gastric emptying: an Experimental study. J Postgrad Med 43(1):12-13. Vani T, Rajani M, Sarkar S, and Shishoo CJ. Antioxidant Properties of the Ayurvedic Formulation Triphala and its Constituents. International Journal of Pharmacognosy Vol 35, No. 5, 1997:313-3

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Vitaberry Plus + Super Fruit Antioxidant
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Date: December 07, 2005 05:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitaberry Plus + Super Fruit Antioxidant

Vitaberry Plus +™ Super Fruit Antioxidant

By Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive Free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),
- Catalase (neutralizes peroxides),
- Functions similar to reduced Glutathione (GSH),
- Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent),
- Functions similar to Glutathione S-transferase (GST),
- Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/

ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697

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Life is more enjoyable when your stomach is prepared for it.
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Date: November 28, 2005 12:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Life is more enjoyable when your stomach is prepared for it.

PepZin GI for the stomach.

Life is more enjoyable when your stomach is prepared for it.

With the inevitable ups and downs of every day life, the importance of maintaining a healthy stomach is just good common sense. Because it is the immune system’s first line of defense, compromising the lining of the stomach could have a ripple effect in other parts of the body. Many things can impact the stomachs mucosal lining, including bacterial imbalances, poor metabolism of carbohydrates, too much aspirin, alcohol use, or just a spicy diet.

PepZinGI, from Doctor’s Best, is an exclusive, patented complex of zinc and l-carnosine that offers remarkable stomach support. A special chelated form of zinc that breaks down more slowly in the stomach, PepZinGI is able to exert its effects directly on the cells lining the stomach for a longer period of time. Clinical trials involving controlled, double-blind comparative studies of patients with gastric discomfort clearly demonstrated the superior ability of zinc-l-carnosine to help the body cope better. By helping to prevent Free-radical damage, supporting cell growth and metabolism, and maintaining proper balance of bacteria in the stomach, PepZin GI can provide effective support of its crucial mucosal lining.*

*These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Pepzin GI 120VC from Doctors Best


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Benefits of Alpha Lipoic Acid
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Date: October 13, 2005 05:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Alpha Lipoic Acid

Benefits of Alpha Lipoic Acid

  • Supports the Body’s Defense Against Free Radicals*
  • Recycles Antioxidant Nutrients such as Vitamin C and Vitamin E*
  • Helps Maintain a Healthy Blood Sugar Level when used as part of the diet*

    Alpha-lipoic Acid––the "Ideal Antioxidant"

    The antioxidant potential of a substance is based on a number of criteria, including:
    1) Ability to quench specific Free-radicals.
    2) Ability to bind or "chelate" metal ions that can generate free radicals.
    3) Supports function of other antioxidants.
    4) Absorption/bioavailability.
    5) Concentration in tissues, cells and extra cellular fluids.
    6) Ability to function as an antioxidant in fatty and watery environments.

    The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.

    As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3
    1) ALA is easily absorbed when consumed orally.
    2) ALA is readily converted to DHLA in various tissues.
    3) As a pair, ALA and DHLA neutralize superoxide, hydroxyl, peroxyl, and hypochlorus radicals.
    4) ALA and DHLA form stable complexes with metal ions such as iron, manganese, copper and zinc ions.
    5) ALA and DHLA scavenge free radicals in fatty environments and watery environments.
    6) DHLA recycles other important antioxidants.

    DHLA-regenerates vitamin C, vitamin E and glutathione

    Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants.

    DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7

    Alpha-lipoic Acid and Blood Sugar

    Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10

    Scientific References

    1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50.

    2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63.

    3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31.

    4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21.

    5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561.

    6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637.

    7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87.

    8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4.

    9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14.

    10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804.



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    Benefits of Total Daily Formula
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    Date: October 13, 2005 04:45 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Benefits of Total Daily Formula

    Benefits of Total Daily Formula

    Mixed Carotenoids

    All fruits and vegetables contain carotenes, the plant pigments responsible for the rich variety of colors we enjoy in the natural world. Beta carotene is the most familiar member of the carotene family. But beta carotene never exists by itself; it is always found with other carotenes in foods. We need more than just beta carotene alone. Carotenes are powerful antioxidants, which means they help reduce the body's free radical burden. Research suggests that carotenes work as a team to keep us healthy.5 Total Daily Formula provides beta carotene, alpha carotene, lutein, lycopene, zeaxanthin and cryptoxanthin from natural sources such as algal extracts, carrot oil, marigold and tomatoes (Caromix®).

    Corn-Free Vitamin C

    Total Daily Formula uses only corn-free vitamin C (ascorbic acid). The full daily intake of 6 tablets provides an exceptionally generous 800 mg of vitamin C.

    Optimum B Vitamin Servings

    Total Daily Formula supplies ample amounts of all essential B vitamins. Vitamin B3 is given as niacin plus an extra helping of niacinamide, the non-flush form of this important vitamin. The body uses pantothenic acid (vitamin B5) to deal with stress, so the formula provides 150 mg, which is 15 times the RDA. Vitamin B6 is another B vitamin people may run short of, so 60 mg -- 30 times the RDA -- is supplied. The formula contains 800 mcg of folic acid, the vitamin now recognized by the FDA as essential for prevention of neural tube defects in unborn babies. Folic acid also helps prevent accumulation in the body of homocysteine, a metabolite of the amino acid methionine.6 A high blood homocysteine level is now considered to be a risk factor for heart disease.7

    Flavonoids

    Flavonoids, also known as "bioflavonoids." are plant pigments widely distributed throughout the plant kingdom.8 Previously known as "Vitamin P," because they help reduce capillary permeability (leakiness) flavonoids are now regarded as "semi-essential" non-vitamin nutrients that benefit health in a variety of ways.9 In addition to maintaining the structure of blood vessels, flavonoids function as versatile antioxidants. Flavonoids protect vitamin C from destruction by Free-radicals, helping to preserve the body's vitamin C supply.10 Total Daily Formula provides 100 mg of pure flavonoids from 112 mg of citrus extract.

    Three superior sources of Calcium

    Total Daily Formula contains three of the best absorbed and most effective forms of calcium available. MCHC (microcrystalline hydroxyapatite concentrate) is a naturally-derived compound composed of calcium, plus all the minerals and organic factors in living bone tissue. MCHC has been clinically shown to benefit bone health.11 Calcium citrate malate is a very well-absorbed form of supplemental calcium shown in recent research to be helpful for postmenopausal women.12,13 Calcium glycinate is chelated with the amino acid glycine, one of the most efficient mineral carriers for effective absorption.14,15

    Magnesium glycinate

    Magnesium is essential for strong bones and healthy hearts. This versatile mineral also regulates nerve function, keeps muscles relaxed and coordinates activity of over 300 enzymes in the body.16 Total Daily Formula contains 100 percent magnesium glycinate for exceptional absorption and gentleness on the intestinal tract.17 Magnesium glycinate has been clinically tested on people with severe malabsorption with excellent results.18

    Trace Minerals

    Total Daily Formula provides - in addition to zinc, chromium, selenium and iodine - vanadium and molybdenum. Vanadium helps maintain normal blood sugar.19 Molybdenum works as a co-factor for enzymes that help detoxify and eliminate foreign substances from the body.20

    Bioperine® for Enhanced Absorption

    Bioperine® is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine®. 21 Betaine HCL - supplies HCL (hydrochloric acid) to assist digestion. All natural tablet coating made of vegetable concentrate and beta carotene.

    Scientific References
    1. Cheraskin, E. Ringsdorf, W.M., Clark, J.W. 1968. Diet and Disease. (p. 16). New Canaan, CT: Keats Publishing.

    2. Morgan, K.J. et. al. Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition. 1985;4:195-206.

    3. Lakschmanan, F.L., Rao, R.B., Kim, W.W., Kelsay, J.L. Magnesium intakes, balances and blood levels of adults consuming self-selected diets. American Journal of Clinical Nutrition 1984;40:1380-89.

    4. Mertz, W. The Essential Trace Elements. Fed. Proc. 1970;29:1482.

    5. Perry, G. Byers, T. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Annu. Rev. Nutr. 1992;12:139-59.

    6. Landgren, F., et. al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Int Med 1995;237:381-88.

    7. Clarke, R., et. al. Hyperhomocysteinemia: an independent risk factor for vascular disease. New Eng J Med 1991;324:1149-55. 8. Havsteen, B. Flavonoids, a class of natural compounds of high pharmacological potency. Biochemical Pharmacology 32(7):1141-48.

    9. Middleton, E. The flavonoids. TIPS 1984; 5:335-38.

    10. Roger, C.R. The nutritional incidence of flavonoids: some physiological and metabolic considerations. Experientia 44(9):725-804.

    11. Dixon, A. St. J. Non-hormonal treatment of osteoporosis. British Medical Journal 1983;286(6370):999-1000.

    12. Smith, K.T. et. al. Calcium Absorption from a new calcium delivery system (CCM). Calcif Tissue Int 1987;41:351-352.

    13. Dawson-Hughes, B. et. al. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. New England Journal of Medicine 1990 Sep 27;323(13):878-883.

    14. Albion Research Notes Vol. 4, No. 1, ©Albion Laboratories Jan,1995.

    15. Ashmead, H.D. Intestinal Absorption of Metal Ions and Chelate, Springfield: Charles C Thomas, ©1985.

    16. Wester, P.O., Dyckner, T. The importance of the magnesium ion. Magnesium deficiency-symptomatology and occurrence. Acta Med Scand 1992; (Suppl) 661:3-4.

    17. Albion Research Notes Vol. 3, No. 1, ©Albion Laboratories, Feb 1994.

    18. Schutte, S., et. al. Bioavailability of Mg diglycinate vs MgO in patients with ileal resections. Abstract 115, AJCN 1992;56(4).

    19. Cohen, N. et. al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin Invest 1995; 95:2501-09.

    20. Sardesi, V.M. Molybdenum: An essential trace mineral element. Nutr Clin Pract 1993; 8:277-81.

    21. Bioperine® - Nature's Bioavailability Enhancing Thermo-nutrient. Executive Summary' 1996; Sabinsa Corporation, Piscataway, N.J.



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    Curcumin - Turmeric Extract
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    Date: August 19, 2005 12:47 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Curcumin - Turmeric Extract

    Curcumin

    Turmeric- History and Traditional Usage

    Native to Southeast Asia, Curcuma longa is a tall
    tropical shrub with large oblong leaves and pale yellow flowers.
    The genus “Curcuma” belongs to the Zingiberaceae family, which
    includes ginger.1 The plant possesses a large root structure
    with fleshy, bulbous underground parts called “rhizomes.” These
    rhizomes, known as turmeric root, are harvested at maturity,
    dried and cured for commercial use. Chemical analysis shows that
    dried turmeric contains essential and volatile oils, with a
    curcuminoid content of 2.5 to 5.0 %.2

    In addition to its
    popularity as a spice, turmeric is used as a dye for cloth and
    coloring agent in foods and cosmetics, thanks to its rich yellow
    color. Turmeric also serves as a preservative, probably owing to
    the antioxidant and antimicrobial properties of curcumin.
    Extracts of Curcuma longa have demonstrated in vitro
    antibacterial and anti-fungal effects.3

    Turmeric is named in
    ancient Ayurvedic and Chinese herbal texts as a traditional folk
    remedy. Historically, turmeric was used externally for wounds,
    and sprains, and internally for digestive complaints,
    rheumatism, liver disorders, coughs and colds.4
    Benefits

    Protects cells and tissues by fighting free radicals.*

    Supports joint function*

    The numerous beneficial
    effects attributed to turmeric stem in large measure from the
    antioxidant properties of curcumin. Antioxidants neutralize free
    radicals, which are highly unstable molecules that can damage
    cellular structures through abnormal oxidative reactions.
    Curcumin is a potent “scavenger” of the superoxide radical, a
    free radical that initiates potentially harmful oxidative
    processes such as lipid peroxidation.5 Through this activity,
    curcumin has been shown to protect skin cells from the injurious
    effect of nitroblue tetrazolium, a toxin that generates
    superoxide radicals. Curcumin also increases survival of cells
    exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
    which stimulates superoxide and hydrogen peroxide production.
    Curcumin itself is not toxic to cells, even at high
    concentrations. Pure curcumin was shown to be less protective
    than a mixture of curcuminoids, indicating a possible synergism
    among curcuminoids.6 Because free radicals are involved in aging
    and exert harmful effects on skin, these results suggest
    curcumin may help slow skin aging.

    Curcumin demonstrates
    several other in vitro effects linked to free radical
    scavenging. Curcumin scavenges nitric oxide, a compound
    associated with the body’s inflammatory response.7 Pure curcumin
    and turmeric extracts protect red blood cells from lipid
    peroxidation induced by hydrogen peroxide.8 Curcumin has been
    shown to protect DNA from oxidative damage, inhibit binding of
    toxic metabolites to DNA, and reduce DNA mutations in the Ames’
    test.9 Although additional studies suggest an anticarcinogenic
    effect of curcumin, through protection of DNA,10 one in vitro
    study found that curcumin induced DNA damage in human gastric
    mucosal cells.11 It is speculated that curcumin may act as a
    pro-oxidant in the presence of transition metal ions such as
    copper and iron. (This is true for other antioxidants, including
    vitamin C.) Curcumin also demonstrates in vitro inhibition of
    COX-I and COX-II enzymes, which are involved in the inflammatory
    reaction.12 Together these results strongly suggest that
    curcumin is a potent bioprotectant with a potentially wide range
    of therapeutic applications.

    Animal studies- In vivo protective effects

    Through its free radical scavenging
    properties, curcumin has shown bioprotective effects in animals.
    In one study, rats were treated with isoproterenol, a chemical
    that causes cardiac hypertrophy (enlargement of the heart) due
    to abnormal collagen metabolism. Co-treatment with curcumin
    reversed the degradation of collagen and cardiac hypertrophy
    induced by isoproterenol.13 Curcumin protects mice from
    detrimental effects of radiation, by stabilizing the glyoxalase
    system, a biological system that regulates cell division.14
    Curcumin protects livers of rats from the damaging effects of
    carbon tetrachloride (CCl4), a potent hepatoxin that injures the
    liver via its free radical metabolite, CCl3.15,16 Curcumin
    protected rats from alcohol-induced brain damage, in a study in
    which oral administration of curcumin reversed lipid
    peroxidation, reduced levels of Free-radical metabolites and
    increased levels of glutathione, a major physiologic
    antioxidant.17 Curcuma longa extracts have shown
    anti-inflammatory effects in rats.18

    Human Trials

    Curcumin exhibits Free-radical scavenging ability when
    administered to humans. In an open trial (uncontrolled), 18
    healthy individuals ranging in age from 27 to 67 years consumed
    a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
    for 45 days. Before and after blood tests showed a statistically
    significant decrease in lipid peroxides.19 Preliminary trials
    have tested the anti-inflammatory action of curcumin, with
    results that verify the traditional use of turmeric as an
    anti-rheumatic herb. In a short-term double-blind, cross-over,
    comparative study, 18 people received curcumin (1200 mg daily)
    or phenylbutazone for two week periods. Both curcumin and
    phenylbutazone produced measurable improvements in joint
    flexibility and walking time. The subjects reported results only
    with phenylbutazone, which may be explained by the short
    duration of the trial.20 In a small placebo-controlled trial
    comparing curcumin to phenylbutazone, 45 patients with
    post-operative inflammation received curcumin, phenylbutazone or
    placebo. The anti-inflammatory effects of curcumin and
    phenylbutazone were comparable and superior to placebo.21
    Curcumin has not been found to produce an analgesic (pain
    relieving) effect.

    Bioperine-Nature’s Absorption Enhancer
    Boosts Curcumin Absorption*

    Traditional Ayurvedic herbal
    formulas often include black pepper and long pepper as
    synergistic herbs. The active ingredient in both black pepper
    and long pepper is the alkaloid, piperine. Experiments carried
    out to evaluate the scientific basis for the use of peppers have
    shown that piperine significantly enhances bioavailability when
    consumed with other substances.22 Several double-blind clinical
    studies have confirmed that Bioperine® increases absorption of
    nutrients.23

    Curcumin is poorly absorbed in the intestinal
    tract, limiting its therapeutic effectiveness. Oral doses are
    largely excreted in feces, and only trace amounts appear in the
    blood. Concomitant administration of 20 mg of piperine with 2
    grams of curcumin increases the bioavailability of curcumin by
    2000%.24

    Scientific References


    1. Majeed, M., Badmaev,
    V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
    Piscataway, NJ: NutriScience Publishers.
    2. Srimal, R.C.
    Turmeric: a brief review of its medicinal properties.
    Fitoterapia 1997;68(6):483-93.
    3. Ammon, H.P.T., Wahl, M.A.
    Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
    4.
    Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
    The Protocol Journal of Botanical Medicine, Autumn
    1995:43-46.
    5. Rao, N.S., Rao, M.N.A. Free radical scavenging
    activity of curcuminoids. Arzneim.-Forsch./Drug Res.
    1996;46(2):169-171.
    6. Bonté. F. et al. Protective effect of
    curcuminoids on epidermal skin cells under free oxygen radical
    stress. Planta Medica 1997;63:265-66.
    7. Rao, S., Rao, M.N.A.
    Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol.
    1997;49:105-7.
    8. Lalitha, S., Selvam, R. Prevention of
    H2Os-induced red blood cell lipid peroxidation by aqueous
    extracted turmeric. Asia Pacific J Clin Nutr
    1999;8(2):113-14.
    9. Deshpande, S.S., Maru, G.B. Effects of
    curcumin on the formation of benzo[a]pyrene derived DNA adducts
    in vitro. Cancer Letters 1995;96:71-80.
    10. Subramanian, M., et
    al. Diminution of singlet oxygen-induced DNA damage by curcumin
    and related antioxidants. Mutation Research
    1994;311:249-55.
    11. Blasiak, J., Trzeciak, A., Kowalik, J.
    Curcumin damages DNA in human gastric mucosa cells and
    lymphocytes. Journal of Environmental Pathology, Toxicology and
    Oncology 1999;18(4):271-76.
    12. Ramsewak, R.S., DeWitt, D.L.,
    Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
    activities of Curcumins I-III from Curcuma longa. Phytomedicine
    2000;7(4):303-308.
    13. Nirmala, C. Anand, S., Puvanakrishnan,
    R. Curcumin treatment modulates collagen metabolism in
    isoproterenol induced myocardial necrosis in rats. Molecular and
    Cellular Biochemistry 1999;197:31-37.
    14. Choudhary, D.,
    Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
    system by curcumin. Journal of Ethnopharmacology
    1999;64:1-7.
    15. Park, E-J. et al. Protective effect of
    curcumin in rat liver injury induced by carbon tetrachloride. J
    Pharm. Pharmacol. 2000;52:437-40.
    16. Deshpande, U.R. et al.
    Protective effect of turmeric (Curcuma longa L.) extract on
    carbon tetrachloride-induced liver damage in rats. Indian
    Journal of Experimental Biology 1998;36:573-77.
    17.
    Rajakrishnan, V. et al. Neuroprotective role of curcumin from
    Curcuma longa on ethanol-induced brain damage. Phytotherapy
    Research 1999;13:571-74.
    18. Arora, R.B. Basu, N., Kapoor, V.,
    Jain, A.P. Anti-inflammatory studies on Curcuma longa
    (Turmeric). Indian J Med Res 1971;59(8):1289-95.
    19.
    Ramirez-Bosca, A. et al. Antioxidant curcuma extracts decrease
    the blood peroxide levels of human subjects. Age
    1995;18:167-69.
    20. Deodhar, S.D., Sethi, R. Srimal. R.C.
    Preliminary study on antirheumatic activity of curcumin
    (diferoyl methane). Indian J Med Res 1980;71:632-34.
    21.
    Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
    anti-inflammatory property of curcumin (diferoyl methane) in
    patients with postoperative inflammation. International Journal
    of Clinical Pharmacology, Therapy and Toxicolgy
    1986;24(12):651-54.
    22. Atal, C., Zutshi, U., Rao, P.
    Scientific evidence on the role of Ayurvedic herbals on
    bioavailability of drugs. Journal of Ethnopharmacology
    1981;4:229-232.
    23. Bioperine®–Nature's Bioavailability
    Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
    Corporation, Piscataway, N.J.
    24. Shoba, G., et al. Influence
    of piperine on the pharmacokinetics of curcumin in animals and
    human volunteers. Planta Medica 1998;64(4):353-6.

    © 2002
    Doctor's Best, Inc. Revised 8/13/02

    *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.



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    WHAT EXACTLY IS PYCNOGENOL?
    TopPreviousNext

    Date: July 13, 2005 09:42 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: WHAT EXACTLY IS PYCNOGENOL?

    WHAT EXACTLY IS PYCNOGENOL?

    Pycnogenol is a super antioxidant which consists of a highly bioavailable flavonoid called proanthocyanidin. This compound can be extracted from either pine bark or grape seed, and both sources are virtually identical. Biochemists will confirm that as a class, the proanthocyanidin bioflavonoids, regardless of their source, possess the same biochemical activity with very slight exceptions.

    The differences lie in the varying concentrations of the flavonoid and its purity. Extraction processes for each source d i ffer and may contribute to the cost of the type of Pycnogenol in question. Regardless of its source, Pycnogenol has demonstrated extraordinary antioxidant capabilities.

    NATURE’S BEST DEFENSE AGAINST FREE RADICALS: ANTIOXIDANTS

    Potent substances called antioxidants, which scavenge for dangerous free radicals, afford us the best prospect for disease prevention, toxin protection and sustained longevity and vigor. According to many experts, making sure we arm our cellular systems with adequate supplies of antioxidants should be our first health priority. “It has now been established that more than 60 human diseases involve Free-radical damage, including cancer, heart disease and the acceleration of the aging process. All that you really need to know is that your body is under constant free - radical atta ck, and that you need to keep your antioxidant defenses strong.”1 The role of Pycnogenol as an exc e ptional free radical scavenger is just beginning to emerge, and the protective potential of Pycnogenol is impressive, to say the least. It’s only a matter of time before scientific data supports the fact that this family of nutrients is far more effective in its antioxidant capacity than previously assumed.

    OTHER ANTIOXIDANTS

    Some of the most common of free radical scavengers or antioxidants include:

  • • Vitamin E
  • • Vitamin C
  • • Vitamin A and Beta Carotene
  • • Coenzyme Q-10
  • • Selenium

    While all of these are excellent cellular protectants, the compound missing from the above list may be the most remarkable of all.

    PYCNOGENOL: THE HERCULES OF ANTIOXIDANTS

    Pycnogenol provides some of the most potent compounds known to nutritionally support and potentiate the body’s defense system against oxidants. Continually emerging research supports the fact that Pycnogenol may be the best antioxidant nature has to offer. In this regard, it is 50 times more potent than vitamin E and 20 times more so than vitamin C.2 Pycnogenol is considered by some health experts to be the greatest nutritional breakthrough of our century.

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    Quercetin and Bromelain - for better health.
    TopPreviousNext

    Date: July 04, 2005 10:28 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Quercetin and Bromelain - for better health.

  • Maintains Tissue Comfort by Regulating Enzymes*
  • Helps Maintain Normal Blood Viscosity*
  • Bromelain May Enhance Quercetin Absorption
  • Benefits

    Down-regulates the Body’s Response to Environmental Challenges Quercetin is a member of the flavonoid family, a diverse group of low molecular-weight compounds found throughout the plant kingdom. Flavonoids exhibit numerous biological activities, many of which are directly beneficial to human health. Quercetin, which belongs to the “flavonol” subgroup, is one of the most versatile and important flavonoids. Quercetin has a broad range of activity, much of which stems from its interaction with calmodulin, a calcium-regulatory protein.1 Calmodulin transports calcium ions across cellular membranes, initiating numerous cellular processes. Quercetin appears to act as a calmodulin antagonist.1 Through this mechanism, quercetin functions at the cell-membrane level with a membrane-stabilizing action.2 Quercetin inhibits calmodulin-dependent enzymes present at cell membranes such as ATPases and phospholipase, thereby influencing membrane permeability.3 Quercetin affects other calmodulin-dependent enzymes that control various cellular functions, including the secretion of histamine from mast cells.4 A number of investigations have corroborated quercetin’s ability to reduce histamine secretion from mast cells in various tissues, and also from basophils.5,6,7,8,9,10

    Quercetin modifies the body’s response to antigenic substances.* Suppression of histamine secretion from mast cells is one of quercetin’s most clinically important effects. Quercetin acts on ATPase at the membranes of histamine-containing granules in mast cells.3 Mast-cell degranulation and subsequent release of histamine into the bloodstream is an integral part of the body’s response to environmental challenges.

    Maintains Tissue Comfort by Regulating Enzymes*

    Quercetin’s enzyme-inhibiting action extends to enzymes such as phospholipase, which catalyzes the release of arachidonic acid from phospholipids stored in cell membranes.4,10 Arachidonic acid serves as the key substrate for substances such as thromboxanes, inflammatory prostaglandins and leukotrienes. In addition, quercetin inhibits the enzymes cyclooxygenase and lipoxygenase, which catalyze the conversion of arachidonic acid into its metabolites.4,10,11,12 Reducing levels of these metabolites, as well as histamine levels, is beneficial in maintaining the normal comfort level of body tissues and structures.

    Quercetin has also been shown to limit the function of adhesion molecules on endothelial cells.13 Adhesion molecules are involved in physiologic processes that influence tissue comfort.13

    Bromelain is a complex substance derived from the pineapple stem largely composed of proteolytic (protein-digesting) enzymes. Bromelain acts by a variety of mechanisms to help maintain tissues in a normal state of comfort.14,15 Several investigators, including Taussig16 and Ako, et. al.,17 have presented evidence that bromelain is a fibrinolytic agent, i.e., it induces the breakdown of fibrin, a plasma protein that blocks tissue drainage. The generally accepted mechanisms involve direct proteolysis of fibrin by bromelain and activation of plasmin, a serum protease.16 Plasmin acts on fibrinogen (the precursor to fibrin), forming peptides which stimulate PGE1, a prostaglandin that helps maintain tissue comfort.16

    Helps Maintain Health of Blood Vessels by Modifying Oxidation of LDL Cholesterol* — Quercetin’s Antioxidant Action Quercetin is a versatile and effective antioxidant that scavenges a variety of Free-radicals such as hydroxyl and lipid peroxy radicals.18 Quercetin also chelates ions of transition metals such as iron, which can initiate formation of oxygen free radicals.18 LDL cholesterol is vulnerable to oxidation by lipid peroxides. Oxidized LDL is absorbed by macrophages and arterial endothelial cells, leading to the formation of “foam cells,” and eventually plaque deposits, in arterial walls. Quercetin has been shown to protect LDL from oxidation, both by lipid peroxides and transition metal ions.19

    Helps Maintain Normal Blood Viscosity*

    Quercetin inhibits blood platelet aggregation (clumping), by potentiating PGI2, an anti-aggregatory prostaglandin, and by raising platelet cyclic AMP levels.20 Human studies have revealed that bromelain also reduces platelet aggregation.21 These properties qualify both quercetin and bromelain as valuable dietary ingredients for maintaining cardiovascular health.*

    Bromelain May Enhance Quercetin Absorption

    In addition to the actions described above that support the effects of quercetin, bromelain may also assist the absorption of quercetin in the G.I. tract. (Quercetin is generally believed to be poorly absorbed, although a recent study by Hollman et. al.,22 which concluded that humans do in fact absorb appreciable amounts of quercetin, contradicts this assumption.) Studies have shown that bromelain enhances absorption of antibiotics, presumably by increasing permeability of the gut wall.23, 24 Given that quercetin is a low molecular-weight compound, it is plausible that simultaneously ingested bromelain likewise enhances quercetin absorption.

  • *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
  • Scientific References

    1. Nishino, H., et. al., “Quercetin interacts with calmodulin, a calcium regulatory protein.” Experientia 1984;40:184-5.
    2. Busse, W.W., Kopp, D.E., Middleton, E., “Flavonoid modulation of human neutrophil function.” J. Allergy Clin. Immunol. 1984;73:801-9.
    3. Havsteen, B,. “Flavonoids, a class of natural products of high pharmacological potency.” Biochemical Pharmacology 1983;32(7):1141-48.
    4. Middleton, E., “The Flavonoids.” Trends in Pharmaceutical Sciences 1984;5:335-8.
    5. Otsuka, H. et. al., “Histochemical and functional characteristics of metachromatic cells in the nasal epithelium in allergic rhinitis: Studies of nasal scrapings and their dispersed cells.” J. Allergy Clin. Immunol.1995;96:528-36.
    6. Fox, C.C., et. al., “Comparison of human lung and intestinal mast cells.” J. Allergy and Clin. Immunol. 1988;81:89-94.
    7. Pearce, F.L., Befus, A.D., Bienenstock, J., “Mucosal mast cells III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.” J. Allergy and Clin. Immunol. 1984;73:819-23.
    8. Middleton, E. Drzewiecki, G., Krishnarao, D., “Quercetin: an inhibitor of antigen-induced human basophil histamine release.” J. of Immunology 1981;127(2):546-50.
    9. Bennett, J.P., Gomperts, B.D., Wollenweber, E.,“ Inhibitory effects of natural flavonoids on secretion from mast cell and neutrophils.” Arzneim. Forsch/Drug Res. 1981;31(3):433-7.
    10. Middleton, E. Drzewiecki G., “Naturally occurring flavonoids and human basophil histamine release.” Int. Archs Allergy appl. Immun. 1985;77:155-7.
    11. Yoshimoto, T. et. al., “Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase.” Biochemical and Biophysical Research Communications 1983;116(2):612-18.
    12. Della Loggia, R., et. al., “Anti-inflammatory activity of benzopyrones that are inhibitors of cyclo- and lipo-oxygenase.” Pharmacological Research Communications 1988; 20(Supp. V):91-94.
    13. Middleton, E., Suresh, A., “Quercetin inhibits lipopolysaccharide-induced expression of endothelial cell intracellular adhesion molecule-1.” Int. Arch. Allergy Immunol. 1995;107:435-6.
    14. Taussig, S.J., Batkin, S., “Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application.” An Update Journal of Ethnopharmacology 1988;22:191-203.
    15. Lotz-Winter, H., “On the pharmacology of bromelain: An update with special regard to animal studies on dose-dependent effects.” Planta Medica 1990;56:249-53.
    16. Taussig, S.J., “The mechanism of the physiological action of bromelain” Medical Hypothesis 1980;6:99-104.
    17. Ako, H. Cheung, A.H.S., Matsuura, P.K., “Isolation of a fibrinolysis activator from commercial bromelain.” Arch. Int. Pharmacodyn. 1981;284:157-67.
    18. Afanas’ev, I.B. et. al., “Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.” Biochemical Pharmacology 1989;38(11):1763-69.
    19. De Whalley, C.V., “Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages.” Biochemical Pharmacology 39(11):1743-50.
    20. Beretz, A. Stierle, A., Anton, R. Cazenave, J., “Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin.” Biochemical Pharmacology 1981;31(22):3597-600.
    21. Heinicke, R. van der Wal, L. Yokoyama, M., “Effect of bromelain (Ananase®) on human platelet aggregation. ”Experientia 1972;28(7):844.
    22. Hollma, P. et. al., “Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers.” Am. J. Clin. Nutr. 1995;62:1276-82.
    23. Giller, F.B., “The effects of bromelain on levels of penicillin in the cerebrospinal fluid of rabbits.” A., J. Pharm. 1962;134:238-244.
    24. Bodi, T., “The effect of oral bromelain on tissue permeability to antibiotics and pain response to bradykinin; double-blind studies on human subjects.” Clin. Med. 1965;72:61-65



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    Vision Quest - help fight eye problems.
    TopPreviousNext

    Date: June 18, 2005 08:34 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Vision Quest - help fight eye problems.

    Vision Quest by Phyllis D. Light, RH Energy Times, February 11, 2004

    Since your eyes are in constant use every day, exposed to the damaging energy of sunlight and pollutants that waft through the air, these delicate orbs are often in danger of wearing out.

    To keep this vital part of your anatomy functioning as you age, you have to feed and care for your eyes properly. Otherwise, you are in real danger of losing your vision and independence.

    Your vision may be in danger. Experts estimate that 8 million Americans over the age of 55 are at serious risk of blindness linked to a condition called age-related macular degeneration (AMD). AMD can wipe out your central vision and is the primary cause of blindness in Western society.

    While AMD causes no pain, it blurs the sharp, central vision necessary for driving, reading and other activities where you need to see either up close or straight ahead. During AMD, the macula, the part of the eye that allows you to pick out fine detail, is destroyed. The macula sits at the center of your retina, the nerve center at the back of your eye that senses light and sends optic signals to the brain.

    Age is not the only risk factor for AMD. Scientists have isolated a genetic defect that can lead to some forms of macular degeneration (Nature Genetics 2001; 27:89-93). Smoking and excessive exposure to sunlight are other hazards best avoided if you want to save your sight.

    In many cases, AMD progresses so slowly that victims of this condition don't even notice that their vision is deteriorating until much of it is irrevocably gone.

    Dry and Wet AMD

    Wet AMD occurs when blood vessels in back of the retina start to overgrow and leak blood. As this occurs, blood and other fluids push on the macula and quickly damage its sensitive nerve endings. When wet AMD occurs, you lose your central vision rapidly. If straight lines appear wavy to you, you may be suffering from wet AMD. If you notice this or other unusual vision changes, contact an eye care specialist as soon as possible. You need what is called a comprehensive dilated eye exam that can uncover signs of AMD.

    Dry AMD strikes the eye when light-sensitive cells in the macula slowly deteriorate, gradually blurring central vision in the affected eye. As dry AMD progresses, a blurry spot in the center of your vision may appear. Eventually, as more of the macula becomes dysfunctional, the central vision in the eye can gradually disappear.

    The most common sign of dry AMD is slightly blurry vision. This can make it hard to recognize faces and also make it harder to read without very bright light. Dry AMD generally attacks both eyes, but vision can be lost in one eye while the other eye stays normal. In the early stages of dry AMD, drusen, yellow deposits that gather under the retina, may form. Dry AMD progresses in three stages:

  • • Early AMD: Small drusen form but vision is unaffected.
  • • Intermediate AMD: Many medium drusen appear or, alternately, one large drusen occurs. Center vision is often blurred and reading requires bright lights.
  • • Advanced Dry AMD: Drusen formation is accompanied by deterioration of tissue in the macula. Blurs in central vision expand, eventually destroying most vision. Note: Because of the fast destruction it causes, wet AMD is an advanced form of this disorder that is considered more severe than the dry version.

    Vitamins and Minerals for AMD

    Fortunately, scientists have found ways to combat AMD: An analysis of a study called the national Age-Related Eye Disease Study (AREDS) shows that more than 300,000 Americans could avoid losing their sight to AMD if they took daily supplements of antioxidant nutrients and zinc.

    This conclusion, reached by scientists at Johns Hopkins' Wilmer Eye Institute, is based on research involving more than 4,500 adults suffering various stages of AMD. The study demonstrated that people who already had some AMD could lower their risk of the more advanced form of this condition by 25% when they took vitamin C, natural vitamin E and beta carotene along with zinc. Those suffering from advanced AMD lowered their chances of losing vision by about 19%. (Supplements did not affect the risk of cataracts or the chances of some vision loss for people in the early stages of AMD.)

    " Without treatment to reduce their risk, we estimate that 1.3 million adults would develop the advanced stage of AMD," says Neil M. Bressler, MD, professor of ophthalmology at Johns Hopkins and author of the current study, published in Archives of Ophthalmology (11/03).

    According to Dr. Bressler and the other researchers, people who now have intermediate AMD (some vision loss) in one eye have about a 1 in 16 chance of having their vision deteriorate until they have advanced AMD. They also calculate that about 1 in 4 of those with intermediate AMD in both eyes and 43% of those with advanced AMD in one eye will develop advanced AMD in five years without treatment.

    In their view, older people at risk of AMD blindness should take daily supplements of 500 milligrams of vitamin C, 400 milligrams of natural vitamin E, 15 milligrams of beta carotene, 80 milligrams of zinc as zinc oxide and 2 milligrams of copper as cupric oxide. Evidence also exists that a diet which is high in fat can cause AMD to progress to an advanced stage. The exceptions: The healthy fats found in fish and nuts (Archives of Ophthalmology 2003; 121:1728-37).

    Lutein Protection

    Oddly enough, some of the same pigments that color vegetables and other foods also color your eyes. And scientists believe that those pigments, which are classified as carotenoids, help protect the eyes by helping them fight off the negative effects of caustic molecules called free radicals. Free radicals are formed when the energy from sunlight strikes the eyes and disrupts the composition of natural chemicals found there.

    When scientists compared healthy eyes with eyes suffering from AMD, they found that AMD eyes contained lower levels of lutein and zeaxanthin, carotenoid pigments contained in egg yolk, spinach, broccoli and other dark green vegetables (Ophthalmology 2003; 109:1780). Furthermore, they found that levels of these chemicals generally decline as you grow older.

    " This research is a major step toward large-scale clinical studies to prove the extent to which lutein and zeaxanthin protect against age-related macular degeneration," says Paul S. Bernstein, MD, PhD, at the University of Utah School of Medicine at Salt Lake. "We know that these carotenoids are specifically concentrated in the macula of the human eye."

    Dr. Bernstein adds that, as you age, taking supplements containing lutein and other antioxidants may lower your AMD risk. In his investigation, people with AMD who did not take lutein had one-third less lutein in their eyes than older people whose vision was normal.

    Avoiding Cataracts

    Another eyesight hazard is cataracts, in which the eye's lens-the part that focuses incoming light onto the retina-becomes cloudy. Cataracts form when the proteins found in the normally clear lens become damaged; signs include progressively blurred vision (especially outdoors), focusing problems, seeing streaks of light from headlights and stoplights, and colors that look faded.

    Cataract is the leading cause of blindness worldwide, according to the World Health Organization. One of every six Americans 40 and older suffers from some degree of cataract; it affects half of all Americans who reach age 80. Nuclear cataracts, the most common form of this disorder, develop in the center of the lens and tend to grow slowly. Cataracts may also develop at the back of the lens; this form is linked to eye trauma and long-term use of certain medications, including steroids.

    Like AMD, cataracts become more common as people age. Up to 40% of individuals between the ages of 75 and 85 have them, compared with only 5% to 10% of those folks under the age of 65. And like AMD, sunlight exposure and smoking increase the risk of developing cataracts, as does the presence of diabetes.

    Lutein and zeaxanthin, the carotenoids that are so plentiful in the macula, are also found in the lens (although in lower concentrations), leading many researchers to believe that these nutrients may help drop your risk of cataract development. Early studies indicate that an increased intake of lutein and zeaxanthin reduces one's chances of needing cataract surgery, the most common surgery in the United States (American Journal of Clinical Nutrition 1999; 70(4):509-16; 517-24).

    Antioxidants and the Lens

    Scientists believe that Free-radical damage is a leading cause of cataracts, and so it isn't surprising that antioxidants have proved useful in preventing this problem.

    Almost 500 women filled out diet questionnaires as part of a very large research effort called the Nurses' Health Study; those who had taken vitamin C supplements for 10 years or longer enjoyed the lowest rates of nuclear cataracts (Archives of Ophthalmology 2001; 119:1009-19).

    So the answer to lowering your risk of eye problems is clear, whether you are already in your mature years or plan to be someday: Lead a healthy, eye-friendly lifestyle, eating a diet filled with colorful fruits and vegetables. Take frequent walks and jogs around the block.

    And yes, when you kick back and take your just-as-frequent doses of antioxidant supplements, you're allowed to take your sunglasses off and see the world clearly.



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    Green Power
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    Date: June 14, 2005 06:11 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Green Power

    Green Power

    by Charles Scott Energy Times, January 4, 2005

    If you want to stave off infections, aging-even liver cancer-get your fill of chlorophyll, a vital nutrient in plants.

    The green in plants possesses unique powers. Green landscapes soothe the soul. A verdant expanse of green vegetation offers comfort, peace and ecological consolation. What makes some plants, including vegetables, green: Chlorophyll, a substance that is also a crucial nutrient for better health.

    Chlorophyll is a special chemical that consists of molecules which enable plants to collect sunlight. In a complex molecular process, vegetation then uses chlorophyll to harness the power from the sun's rays and build carbohydrates from carbon dioxide and water. Those carbohydrates form the basic nutritional building blocks that we and other animals need to survive and thrive.

    Besides enabling the creation of carbohydrates, research shows that chlorophyll itself can help lower our risk of diseases like cancer. A recent study in China demonstrates that daily supplements of a chemical derived from chlorophyll can protect DNA, the genetic material in cells. When DNA is damaged and malfunctions, cells may reproduce wildly and become cancerous tumors. The latest experiments, performed by scientists affiliated with the Johns Hopkins Bloomberg School of Public Health and Oregon State University (OSU), show that chlorophyll and its chemical relatives may insulate DNA from unhealthy changes linked to aflatoxin, a fungus that often contaminates corn, peanuts and soybeans. In China, liver cancer associated with aflatoxin is a widespread problem.

    " In the area of China in which we did our study about one in 10 adults die from liver cancer, and it's the third leading cause of cancer deaths worldwide," says George Bailey, PhD, a professor of environmental and molecular toxicology at OSU. "The findings of this research could be enormously important to many areas of China, Southeast Asia and Africa, where aflatoxin-related liver cancer is a real concern. Many of these deaths might be preventable with supplements that cost pennies a day."

    This research looked at about 180 people in Qidong, China. When people in the study were given supplements containing chlorophyll derivatives, they had less than half the DNA damage of people who didn't take supplements.

    According to the scientists, chlorophyll and similar substances may act as interceptor molecules, blocking the absorption of carcinogens. As John Groopman, professor at the Johns Hopkins School of Public Health, observes, the supplements these people took "...can effectively reduce aflatoxin levels, which should reduce the risk of liver cancer."

    Closer to home, other researchers point out that chlorophyll-rich vegetarian foods may help protect us from carcinogens in the typical American diet.

    If you've ever enjoyed a hunk of grilled meat, you've consumed substances scientists call heterocyclic amines, which are contained in the charred part of meat cooked on a grill. Studies have shown that these tasty tidbits can increase your risk of breast and other types of cancer. (Your risk from charred meat greatly increases if you are also a smoker.) However, if you eat a food like spirulina, a blue-green algae high in antioxidants that also contains plenty of chlorophyll, its protective substances can bind with these carcinogens within your digestive tract and keep them from being absorbed.

    Green Keeps You Younger

    While we always hear that eating more fruits and vegetables enhances our health, new research shows that eating green foods adds extra power to an anti-aging program.

    Two experiments at the University of South Florida Center for Aging and Brain Repair, published in the Journal of Neurobiology (7/15/02), show that spirulina and other greens can help shield the brain from the antioxidant damage that accumulates as one ages and may help reverse declines in learning and memory.

    The first study found that a diet rich in spinach helped lab animals stay smart as they grew older. Spinach's benefits, according to the researchers, are due to its rich antioxidant content, which can counteract free radicals (caustic molecules) created in the body during normal metabolism and increased by exposure to environmental pollutants, sunlight and radiation. When free radicals attack, cell walls and other cellular structures are compromised and DNA can malfunction. A lifetime of Free-radical damage can slow your thinking and may be one of the causes of Alzheimer's and Parkinson's diseases, says Dr. Paula Bickford, lead author on the project.

    The second study found that the protective effect of green plants may be linked to their ability to reverse age-related accumulations of potentially harmful inflammatory substances in the brain. In this research, spirulina improved neuron function, lowered inflammation in the brain and reduced levels of chemicals linked to oxidative damage. In fact, spirulina didn't just slow the deterioration of neurotransmitter interactions caused by aging, it actually improved their function.

    " Not all foods are created equal," says Dr. Bickford. "Cucumbers taste good and have lots of fiber. But unlike spirulina and apples, they are not rich in phytochemicals that have antioxidant or anti-inflammatory effects in the brain."

    Green Immunity

    Aside from assisting brain function, spirulina also seems able to help pump up the immune system. Researchers at the University of California at Davis found that adding spirulina to cultured immune system cells significantly increases the production of infection-fighting cells called cytokines.

    A number of previous laboratory studies have found that spirulina can balance immune response: While easing allergic reactions, this powerful green food also was found to enhance the ability of immune cells called macrophages to both destroy bacteria and eliminate cancerous cells.

    " We found that nutrient-rich spirulina is a potent inducer of interferon-g (13.6-fold increase) and a moderate stimulator of both interleukin-4 and interleukin-1b (3.3-fold increase)," notes Eric Gershwin, professor at UC Davis. "Together, increases in these cytokines suggest that spirulina is a strong proponent for protecting against intracellular pathogens and parasites, and can potentially increase the expression of agents that stimulate inflammation, which also helps to protect the body against infectious and potentially harmful micro-organisms."

    What this means for you: Spirulina holds the potential to help the body protect itself against battalions of infectious invaders. " People have used foods like yogurt and spirulina throughout history," says Judy van de Water, PhD, associate professor at UC Davis. "Through research, we are learning exactly how these foods improve immune system function and how they are a beneficial addition to our diet."

    Throughout the history of life on earth, the healthy development of animal and human life has depended on green plants. Today, as our environment deteriorates and our bodies are under attack from an increasingly polluted world, we need those health-boosting greens more than ever.



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    Home on the Range
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    Date: June 13, 2005 03:52 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Home on the Range

    Home on the Range

    by Janis Jibrin, RD Energy Times, September 5, 1999

    Got chicken? Americans can't seem to get enough of this bird. Last year each of us ate, on average, just about 80 pounds of chicken, a whopping increase over the 49 pounds we each devoured in 1980 and an eight-pound increase from 1995. Part of this food's popularity comes from its lean image as a healthier, less fatty alternative to red meat (don't forget to take the fatty skin off). Chicken's also a cheap protein source: At many popular supermarkets you'll find weekly specials at about a dollar a pound.

    But at health food markets, chicken can cost upwards of $1.69 a pound. These birds may be touted as raised in an organic, stress-free environment and on a vegetarian diet, free of antibiotics. For many people, this poultry is a better buy.

    The Alternative Chicken

    Most of the supermarket chicken you pick up in grocery refrigerated cases are broilers, birds bred to mature in about eight weeks. In comparison, in the '60s, chickens needed 14 weeks to become adult poultry. Conventionally-raised broilers eat grain mixed with whatever's cheapest on the market, such as recycled cooking oil that's been used to fry fast foods and animal parts.

    These birds reside in chicken coops the size of football fields and don't see the light of day until transported to the slaughterhouse. On the other roost, alternatively raised chickens are brought up in a variety of ways (see box), but usually enjoy a more relaxed life and diet.

    Chickens on the farm receive antibiotics for two reasons: To fight off the diseases that can run rampant through a crowded chicken coop and to encourage faster growth.

    Antibiotics Stimulate Growth

    Mark Cook, PhD, professor of animal science at the University of Wisconsin at Madison, explains, "Gut bacteria trigger an immune system assault, which makes chickens a little feverish, suppresses appetite and slows growth. Antibiotics stimulate growth indirectly, by keeping bacteria levels down, and preventing the immune reaction." When birds get sick, they often get dosed with even more antibiotics.

    This widespread antibiotic use has come home to roost and may contribute to the growth of bacteria that, frequently exposed to chemicals, have evolved ways to keep from being killed by pharmaceuticals.

    This development threatens human health. Bacterial infections that people contract, once easily cured by penicillin or other drugs, are now tougher to eradicate. For instance, campylobactor, a common bacteria found in chicken, and responsible for some food poisonings, now demonstrates signs of resistance to drugs like floroquinolones. A powerful class of antibiotics, floroquinolones used to dependably conquer this infection.

    "Floroquinolones are an extremely important class of antibiotics, used to treat many types of infections such as urinary tract infection, a wide variety of gastrointestinal illnesses, pneumonia, almost everything," says Kirt Smith, DVM, PhD, epidemiologist, acute disease epidemiology section, Minnesota Department of Health.

    A study by Dr. Smith, published in the New England Journal of Medicine (340, 1999: 1525-32), showed that the percent of floroquinolone-resistant campylobactor appearing in infected people in his state-Minnesota-climbed from a little over 1% in infected people during 1992 to 10.2% in 1998. He and other scientists strongly suspect that the rise is a direct consequence of the Food and Drug Administration's (FDA) decision to allow floroquinolones in poultry feed beginning in 1995.

    Although it was nearly impossible for Dr. Smith to trace the precise origin of campylobactor poisoning, he believes chicken was usually the source-and not just U.S. chicken. Many of the infected people had returned from Mexico and other countries.

    "Sales of floroquinolones for poultry use in Mexico has increased dramatically," notes Dr. Smith.

    Many alternative chicken producers do not use any antibiotic-laced feed at all. Other farmers adjust the feed to lower gut pH, making it more acidic and lowering chances of bacteria. At the U. of Wisconsin, Dr. Cook is developing antibodies to suppress the immune response to bacteria so chickens won't need antibiotics to spur growth. Buying and dining on chicken raised with little or no antibiotics could beneficially lower your risk of contracting a hardy bacterial infection. Better to catch campylobactor from an antibiotic-free chicken than a conventional chicken, speculates Dr. Cook. "There's less likelihood the bug will be resistant, and a better chance your problem can be cured with antibiotics," he explains.

    And, looking beyond your own immediate health risk, buying antibiotic-free chicken makes a small contribution to stopping the spread of antibiotic resistant bugs. A Matter of Taste Conventionally raised chickens get little exercise and live only eight weeks, so they're tender but bland.

    "There's not much taste in a modern chicken. Free range or organically grown, older birds usually have more taste," notes Dr. Cook.

    The days of barnyard chickens happily clucking and strutting around in picturesque nature have disappeared with the family farm. Today, chickens lead a meager existence. After hatching, baby chicks are tossed into a gigantic hen house that is home to up to 30,000 birds. Their short lives are lived within the United States Department of Agriculture (USDA) mandated 3/4 square foot per chicken. In that squeeze, birds can catch "chicken influenza," especially in winter when it's too cold to let in much fresh air.

    Laying hens don't experience much more of a peaceful existence. These birds live their years with about five other hens, so crowded they can't flap their wings. Cages, suspended in the air, let eggs roll into a holding area. So they don't peck each other, hens are often debeaked, a painful process that can cause infection.

    Hens go through natural laying and "dry" cycles. Growers manipulate this cycle by "forced molting," depriving hens of food for four to 14 days to keep them constantly laying. By the end of two years, hens are worn out. Their inactivity weakens their bones enough that electrical stunning, the usual method for knocking chickens out before slaughter, shatters their bones. So some wind up being plucked and boiled alive, according to Mary Finelli, program director for farm animals and public health at the Humane Society of the United States. The meat from these hens, tougher than other birds, was probably in your deli lunch sandwich. It's also used in the school lunch program or may end up in dog food.

    "Generally, organically-grown broilers and hens have it better because room to move is part of the organic certification process," says Finelli. Finelli suggests visiting chicken suppliers to find out how chickens are treated. Or, she advocates a Humane Society book listing reliable firms. For a local producer call the society: 202-452-1100. According to a Consumer Report report, some growers force chickens out the last week of their lives to brand them "free range." So free range isn't a prime standard for choosing a decently raised chicken. However, turkeys thrive outdoors, so choosing Free-range turkey is often a good idea for better tasting poultry.

    In any case, organic is your best bet for chicken without pesticides. Make it your main choice for your 80 pound yearly consumption!

    To fight cruel treatment of poultry:

    • Forced Molting Ban. Forced molting is shocking hens for more eggs. To support petitions banning forced molting write: Docket Manage-ment Branch, FDA, Dept. Health & Human Serv-ices, 12420 Parklawn Drive, Room 1-23, Rock-ville, MD 20857. Include docket # 98P-0203/CP

    • Downed Animal Protection Bill (House Bill 443, Senate Bill S515) spares some animals from the tortuous journey from chicken house to slaughterhouse. Mandates humane euthanization.



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    Basics of the Immune System
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    Date: June 10, 2005 03:01 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Basics of the Immune System

    Basics of the Immune System

    by Leonid G. Ber, MD Energy Times, September 1, 1998

    In a world filled with pathogens and microbes, good health and resistance to disease is no accident. It requires a vigorous and vigilant immune system. The immune system should be viewed as an internal security force that is constantly checking the identity of everything entering and already existing in the body. A cell or substance may be recognized as "non-self" and a potential enemy if it does not have the right molecular make-up. A cell displaying molecules produced according to a different blueprint than the body's own code may be recognized as foreign. To eliminate alien material that may harm the body, the immune system must take swift action.

    Recognizing entities that originate outside the self forms the key to overall immune system response. This key is carried in the body by cells called macrophages (ma-kro-fajs), a name derived from a Greek term meaning "big eater." Macrophages eat or engulf foreign cells and molecules. When a macrophage encounters something that it distinguishes as being "non-self" or abnormal, it can attack the enemy with a series of assault weapons, including Free-radicals (reactive substances) and enzymes, that dissolve and weaken the intruder. In fact, an enzyme produced by macrophages called lysozyme is recognized as one of nature's most powerful anti-infective agents. These chemical defenses, along with engulfment and complete digestion by macrophages, can effectively stymie invasion by disease-causing pathogens.

    Disease Invasion

    Harmful invasion can originate in the body's own cells as well as begin from outside sources. While we are constantly exposed to bacteria, viruses, fungal cells and parasites, destructive cancerous growths often start within the body.

    Every day, thousands of the body's cells mutate into possible cancers. Under most circumstances, the immune system keeps these cells under control. But when the immune "security" system slips up, these harmful growths multiply unrecognized.

    Getting Specific

    The initial immune response that recognizes invaders is called a "non-specific defense mechanism" since this immune response is generally the same toward all invaders. This counter-attack entails battling every invader pretty much identically: a macrophage can engage, dissolve, weaken, engulf, digest, eliminate. However, if, despite the initial immune efforts, the problem persists, a macrophage can tag an invader and "introduce" it to the rest of the immune system, thus recruiting more specialized types of immune cells to enter the battle. This tagging function endows macrophages with the name "antigen-presenting cells." (Antigens are substances that can provoke specific responses by the immune system.)

    Most antigens are proteins. Proteins are relatively large molecules made of smaller units called amino acids. The specific geometric organization of amino acids is what conveys uniqueness to each protein. (Your genetic code forms a blueprint for the production of your own, individual proteins.) Protein molecules produced by one human being can act as an antigen for another human being. That's why organs transplanted from one person to another can be rejected by the immune system. Unless organs are transplanted from one identical twin to another (who share the genetic blueprint for protein creation), doctors must use immune-suppressing drugs to curtail organ rejection. At the same time as these medicines prevent transplant rejection, they also make people more susceptible to infectious diseases and cancer.

    Specialized Immunity

    After one set of immune cells chemically tags antigens (invaders) for recognition, other highly specialized parts of the immune system go into action: Cells called T cells or T lymphocytes acknowledge the invaders and can take the further action (second line of defense) that is necessary to render them harmless.

    T cells get their name from the thymus (an organ located behind the sternum) where they originate. The thymus, most active when we're young, usually shrinks and apparently slows or shuts down its activity about the age of forty.

    A wide variety of T cells inhabit lymph nodes (soft, usually round, pea- or nut-sized organs) and other body areas. For instance, natural killer cells, as their name implies, are a particularly aggressive type of T cell. Another type of T cell is called T helper (a cell that supports development of immune response). T suppressors halt immune response when infection ends.

    In order to make all these different cells work in concert, cytokines or messenger molecules are produced that facilitate constant communications between all the parts of the immune system.

    The B Team

    Other organs of the immune system include:

    *bone marrow: a powerful cell producing organ where the majority of immune cells are born;

    *spleen: an abdominal organ that forms a reservoir for the production of immune cells.

    Lymph nodes oversee particular segments of the body where they collect and recycle tissue fluids. Like an early warning system, lymph nodes react when an invader is detected in the part of the body that it controls.

    Yet another step in the so-called immune cascade entails action by lymphocytes, called B cells, which originate in the bone marrow. These cells produce antibodies which are immune proteins (immunglobulins) that attack specific antigens.

    While traveling in the blood, an antibody can bind to an antigen, curtailing its harmful action. This bound up molecule forms a complex easily recognized by scavenging macrophages which make a quick meal out of the unlucky invader.

    After enemy cells are removed from the body, knowledge of this victory resides in the immunological memory prolonging your resistance toward specific disease pathogens indefinitely. That's why someone who has recovered from a disease like the measles may be impervious to reinfection.

    Rules for Optimum Immunity

    Even though the immune system consists of a complex team of hard-working cells, enhancing your immunity is relatively easy:

    Maintain a healthy lifestyle. Avoid continuous stress and negative emotions or cope with them through exercise or meditation. Consistent, moderate exercise can boost the immune system. Massage can also help although extreme care must be taken when inflammation or disease is already present.

    Sleep 7-8 hours a day. Sleep allows the body to recover and rebuild. Protein synthesis, vital for a healthy immune system, increases during the night.

    Stick to a healthy diet. Your immune system consists of trillions of cells. Consequently, nutrients important for cell health boost the immune system. A balanced low-calorie diet rich in complex carbohydrates, "good" fats (including fish oils, olive oil and flaxseed oil) along with vitamins, minerals and phytonutrient antioxidants from fresh fruits and vegetables can fortify immune cells. Plus, drinking plenty of water helps improve circulation of lymph fluid.

    These recommendations are not hard to meet once they become a part of your daily routine. However, extra immune security may be necessary during flu season, while traveling long distances (airplanes are notorious sources of pathogens) or when working extensive hours in front of a computer screen. In addition, exposure to x-rays, immunosuppressive chemicals, ultraviolet radiation (the sun) or simply aging may give your immune cells extra burdens.

    Your "specific" immune system does not respond immediately to the challenge of invasion by an infectious organism. Instead, it may require about 2 weeks for an effective reaction after antigen recognition and alerting T cells. During this period, the macrophages' non-specific defense assumes a crucial role in keeping infection in check.

    Enhanced activity by macrophages is especially important for recognizing and destroying cancer cells. The most dangerous cancers are those that can mimic normal cells and avoid the immune system's wrath. Few substances can activate macrophage function in the body (aloe vera contains substances that contribute to this process). The most powerful macrophage activator recognized by the scientific community is a sugar-like substance called beta-1,3-D-glucan. Beta-glucan, extracted from the cell walls of common Baker's yeast, when taken in certain small amounts, can prevent infection by making macrophages more active in recognizing and attacking infectious bacteria, fungi and certain viruses.

    This kind of activation can encourage macrophages to attack previously unrecognized tumor cells. As a result, tumors may be eradicated as the immune system mobilizes and produces what may be known as "spontaneous healing."

    Hungry Macrophages

    When a macrophage works overtime fighting disease, its demand for nutrients and energy increases dramatically. Vitamin C, known for its immune supporting function, seems to be especially important for maintaining fully active macrophages. Vitamin C collects in macrophages, often reaching forty times the concentration found in surrounding blood. What are conventionally considered normal amounts of vitamin C in the body may be insufficient to keep macrophages well supplied with this antioxidant. Therefore, extra amounts of vitamin C can keep the immune system in fighting trim.

    Scientists are only now beginning to uncover the secrets of the highly organized immune system. One thing's certain: The immunity security team depends on proper lifestyle, nutrition and supplements to maintain the critical defenses necessary for good health.

    Dr. Ber received his doctorate in internal medicine from the Yaroslavle, State Medical Institute in Yaroslavle, Russia.



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    Improove Memory ...
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    Date: June 09, 2005 05:49 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Improove Memory ...

    Mesmerizing Memory by Cal Orey Energy Times, January 1, 1999

    In the 60s, the same rock 'n' rollers who belted out "One pill makes you larger and one pill makes you small," often espoused the belief that certain pills could expand the mind. While counter-culture pill purveyors were pilloried for their pill-popping claims, 90s nutritional research has uncovered a stash of supplements that may amplify mental improvement.

    Like a blues singer bending a high note, researchers are now humming with dramatic assertions that certain nutritional supplements can sustain and enhance concentration and memory function. For instance, studies reveal possible benefits for cognitive powers from vitamin C, magnesium and Ginkgo biloba. A recent report in the Journal of the American Medical Association (JAMA 278:1327-1332) said that an extract of Ginkgo biloba "can stabilize and, in some cases, improve the cognitive function and social behavior of demented patients."

    A researcher in the Proceedings of the National Academy of Sciences noted that a daily dose of vitamin E may "help protect the brain and its memories from the ravages of time." And the beat goes on: other evidence indicates that zinc, iron and boron may pump up short-term memory attention span and cut the time it takes to perform mental tasks.

    Neuronutrients
    Neuronutrients-mentally helpful vitamins, minerals, fatty acids, amino acids and trace elements-offer an exciting key to keeping mental functions from succumbing to the degenerations of aging and disease. According to Dharma Singh Khalsa, MD, author of Brain Longevity (Warner Books) and an energetic campaigner for mental fitness through nutrition and exercise, vitamin E "can not only prevent deterioration of the brain, but actually reverse an important element of deterioration." Dr. Khalsa describes vitamin E as one of the most potent antioxidants, a fighter of the electrically charged free radicals that attack and break down cell membranes and nerve endings.

    Lester Packer, PhD, professor of molecular and cell biology at UC Berkeley, told a joint 1996 United Nations-World Health Organization conference on Aging that "there is a growing body of evidence indicating that the free radical theory of aging and aging-related disease is valid," and that dietary and supplemental antioxidants can help fight illness and mental deterioration.

    Vitamin E and other memory aids are believed to protect brain chemicals called neurotransmitters, "the ferrymen of the brain's communication system," that influence concentration and memory. Experts say that sustaining the level of these nerve chemicals in the brain can potentially improve all mental processes.

    Brain Well-Being
    "Your brain is intricately bound up with your physical state of well-being and is, therefore, vulnerable to any kind of physical abuse, especially that of chemical or substance abuse," report Thomas H. Crook III, PhD, and Brenda Adderly, MHA, co-authors of The Memory Cure (Pocket Books).

    Too much alcohol, for example, commonly causes progressive mental decline, according to Secrets of the Superyoung (Villard) by David Weeks and Jamie James. The authors also point out that "the memory tends to worsen noticeably after 15 years of alcohol drinking, and much sooner in people who go on massive binges."

    "The effects of cigarette smoke are subtler because the poisonous effects of carbon monoxide in each puff are temporarily offset by the alerting effects of the nicotine," they add. Can't remember the name of that singer cavorting in a music video? Tests have shown that smokers are worse at connecting peoples' names to their faces than nonsmokers.

    Cognition Ignition
    A first step in beginning your brain-boosting regimen consists of intensified intellectual activity, insists Rebecca Rupp, writer of Committed to Memory: How We Remember and Why We Forget (Crown): n Keep working: The mental challenges and social interactions of a job prevents lapses in the brain's synapses.

    n Learn something new: A second language, musical instrument, or unique puzzles and games keep neurons working like new.

    n Turn off the TV: Read. Studies show that passively watching TV requires less concentration than eating cereal. Mental rejuvenation also requires physical activity. Exercise increases oxygen flow to the brain, which supports memory, concentration and cognition. One study has shown that exercise significantly brightened the moods of middle-aged and older women, regardless of whether they were pre- or post-menopausal, with or without hormone replacement therapy.

    Supplemental Brain Help
    As you provide for your physical and mental vitality through healthy exercise and diet, you can augment your regimens with other supplements that research has shown to boost brain power.

    Antioxidants, including the previously mentioned vitamin E (You haven't forgotten vitamin E already, have you?), provide crucial help for vigorous cerebral function. The free radicals created by tobacco smoke, air pollution, ultraviolet light and certain carcinogenic chemicals deconstruct cell membranes and may foster microscopic brain cell havoc. Antioxidant enzymes convert free radicals to more neutral, benign substances and nutritional antioxidants can neutralize free radicals by linking up with them.

    Vitamin C, a brainy antioxidant all star, performs so well that, according to Dr. Khalsa, its levels in the brain are almost 15 times higher than in other parts of the body. This nutrient, he asserts, aids mental and physical longevity. In a UCLA study, people who ingested at least 300 mg of vitamin C daily lived more than six years longer than those who ingested less.

    Mental Fat
    As a brain protector, selenium ranks high. Your brain consists of about 60% fat and selenium is a master at restricting detrimental fat oxidation. At the same time, zinc takes part in antioxidant processes that quell free radicals and strengthens neuronal cell membranes, protecting nerves from damage.

    Added to this mix, magnesium also scavenges Free-radicals, according to Dr. Khalsa. Plus, experts recommend grape seed extract (phytochemicals that protect a wide range of cellular structures) to safeguard nerve cells and mental capacity.

    B Vitamins for the Mind
    John W. Rowe, MD, president of Mount Sinai Hospital and School of Medicine in New York and author of Successful Aging (Pantheon) states that "there is a significant relationship between blood levels of folic acid and vitamins B12 and cognitive decline." In other words, these vitamins seem to be necessary to eliminate a protein called homocysteine, which has been implicated in the development of coronary heart disease and cognitive problems. (Support for Dr. Rowe's conclusion appeared in the American Journal for Clinical Nutrition 63-306.)

    Iron Mind
    Iron also may strengthen memory. Since iron is involved in distributing oxygen to brain cells (and every other cell in the body), when you lack this mineral you may find it hard to concentrate. In the early 1990s, Harold Sandstead, MD, professor of preventive medicine at the University of Texas, discovered that women whose diets lack zinc and iron experienced more difficulties on standard exams than women with an adequate dietary supply. In his study of women aged 18 to 40, Sandstead found that giving these women more zinc and iron raised their scores on memory tests and average of 20%.

    Boron plays a crucial part in mental function. Scientists at the USDA's Human Nutrition Research Center have linked boron deficiencies to chronic lethargy and fatigue. In brain studies, they found that the electrical activity of the gray matter in the boron deficient indicated increased drowsiness and mental sluggishness.

    Huperzine Boost
    Borrowed from Chinese folk medicine, Huperzine A (HupA) recently has attracted attention from researchers who credit it with enhancing cognitive function and helping folks suffering from disease-related dementia. HupA is an extract of the club moss Huperzia serrata and has been used for centuries in China to treat fever, inflammation and, most recently, dementia. Dr. Alan Kozikowski, professor of chemistry in the neurology department at Georgetown University's Drug Discovery Program, a researcher who first synthesized HupA and studied it extensively, reported in the Journal of the American Medical Association (JAMA, 277 (10):776-March 1997), that HupA is safe, having been used to treat 100,000 people in China.

    HupA basically protects the brain from free radical damage (due to low levels of antioxidant defenses) and maintains or enhances crucial neurotransmitter action. More specifically, HupA helps reduce the breakdown of acetylcholine, the vital neurotransmitter, and makes this substance more bioavailable. In addition, HupA helps make choline accessible to the brain for the synthesis of acetylcholine, according to a study in Neuropharmacology (30, 1991: 763-768).

    Normally, the brain manufactures sufficient levels of the chemical phosphatidylserine, a lecithin-derivative that helps boost neurotransmitter release, but deficiencies of vitamin B12 and folic acid, or of essential fatty acids, may retard that production. Low levels of phosphatidylserine in the brain are related to impaired mental function and depression in the elderly. Scientists reporting in Aging (5, 1993; 123-33) describe "good results" using phosphatidylserine in the treatment of age-related cognitive ills.

    Ginkgo Brain Power
    Researchers also have demonstrated that Ginkgo biloba extract (GBE) increases brain function mostly by boosting acetylcholine receptors and the transmission of nerve impulses, with no significant adverse reactions. GBE is effective not only for folks with Alzheimer's; it also helps when mental function is impaired by vascular deficiencies or depression. Keep in mind that experts believe that GBE requires about 12 weeks of supplementation to reach optimal effectiveness.

    Another ingredient in what seems like an alphabet-soup of brain nourishment is DHA (docosahexaenoic acid), an omega-3 fat essential for normal brain function. Researchers met recently at The New York Hospital-Cornell Medical Center's Nutrition Information Center to discuss "Keeping Your Brain in Shape: New Insights into DHA." Their findings revealed links between low levels of DHA and Alzheimer's, depression, memory loss, attention-deficit/hyperactivity disorder (ADHD) and certain behavioral traits including aggression and hostility.

    Mostly Fat
    Since so much of the brain is fat, material like DHA forms the building block of brain tissue and the primary structural fatty acid in its gray matter. Although it is critical for mental and visual well being, the average American's consumption of DHA has declined since we're eating less of DHA's dietary sources: animal organ meats and eggs.

    Researchers from the National Institutes of Health point out, however, that fish is an excellent dietary source of DHA. In their studies, they discovered that depression rates in Japan and Taiwan, where fish ranks a top spot on the menu, are significantly lower than in North America and Europe.

    DHA also is crucial to the neurological development of children, according to findings published in Pediatrics (vol. 101, no. 1, January 1998). Researchers suggest that DHA-rich breast milk should be the model for infant formulas that enhance babies' neurological development. Scientists also have correlated some behavioral problems in children-ADHD, for example-to DHA deficiencies.

    If you are a vegetarian, or have other cause for concern about a potential lack of DHA in your diet, you can rely on dietary supplementation of DHA. Bruce J. Holub, PhD, of the University of Guelph in Canada provided vegetarians in his research project with DHA supplements over a 42-day period and substantially increased their DHA blood levels.

    The bottom line to enhanced mental performance is to take a balanced approach, says Robert Snider, MD, who specializes in preventive medicine in Massena, New York. "Maintaining brain power includes exercise, stress reduction and good nutrition." The message to keep in mind: Don't lose your nutritional balance or you could lose a piece of your peace of mind.

    Recommended Reading: & Brain Builders (Reward Books, 1995), by Richard Leviton.

    Brain Longevity (Warner Books, 1997), by Dharma Singh Khalsa, MD.

    Omega 3 Oils to Improve Mental Health, Fight Degenerative Diseases and Extend Life (Avery, 1996), by Donald Rudin, MD, and Clara Felix.

    Successful Aging (Pantheon, 1998), by John W. Rowe, MD, and Robert L. Kahn, PhD.



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    AMINO ACIDS AND PROTEIN
    TopPreviousNext

    Date: June 09, 2005 09:48 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: AMINO ACIDS AND PROTEIN

    Amino Acids

    AMINO ACIDS AND PROTEIN

    Next to water, protein is the most abundant substance in the human body. Complex mega-molecules of protein are the structural building blocks of tissue. The thousands of different proteins in our bodies are composed of 20 molecules called amino acids. In the last 20 years, research has shown the benefits of amino acid supplementation to such diverse areas of human biochemistry as metabolism, enzyme and neurotransmitter production and antioxidant protection. Source Naturals utilizes the latest-breaking research to bring you a highly comprehensive line of amino acid supplements.

    Amino Acids

    DNA provides the instruction manual for life, RNA reads the manual and the genetic information is expressed by proteins. Proteins are the most abundant macromolecules in living cells constituting 50% or more of their dry weight. They create the structure of our cells and tissues, and play an essential role in virtually all of the biochemical events that animate those tissues.

    The term "protein" refers to a set of macromolecules that encompasses an extensive variety of structure and function&endash;from helical rods with the tensile strength of steel to elastic sheets to huge molecular machines with hinged jaws that snap closed to hold other molecules in place. Amazingly, all proteins, in their remarkable variety, are built out of a set of 20 simple molecules called amino acids.

    Amino acids are one of the four types of small molecules out of which all life is constructed. The other three are: palmitic acid (see "Essential Fatty Acids," page #), adenine and glucose. All amino acids share a common chemical "backbone" which consists of an a -carbon atom to which four substituent groups are bonded: a nitrogen-containing amino group (H2N), a carboxyl group (COOH), a hydrogen atom and an "R" group. The "R" group or side chain (figure #) varies in electric charge, size, structure and solubility in water, giving each amino acid its distinct chemical properties. Since all amino acids (except glycine) contain at least one asymmetrical carbon atom, each one exists in at least two forms: the l form and its mirror image or stereoisomer, the d form. While both forms are found in biological systems, only the l form is present in proteins.

    Amino acids are linked together like beads on a string to form proteins, sometimes called peptides because of the peptide bonds that link the amino acids together. They range in size from simple two-amino-acid dipeptides to polypeptides which contain more than 1800 connected amino acids. The chemical backbone of the amino acids and their sequence constitutes the primary structure of a protein. Polypeptide chains then fold into specific 2 and 3-dimensional configurations that are unique for each type of protein. The pattern of folds, along with the chemical nature of the amino acid side chains contained in it, give a protein its characteristic biological activity. For example, the connective tissue proteins collagen and elastin give structure to cellular organelles and tissues, while proteins called enzymes catalyze and facilitate metabolic chemical reactions.

    Nine of the 20 amino acids involved in protein synthesis are considered "essential";they cannot be synthesized by the body and must be obtained from food sources. The term "non-essential" is sometimes used to classify the other eleven amino acids. However, this word is perhaps a misnomer; a better term might be synthesizable. These amino acids are just as vital to human metabolism as the "essential" amino acids; so vital that the body can synthesize them. They are, however, more available, more versatile, and more interchangeable.

    When the presence or absence of a particular amino acid will determine whether a protein can be created or not, that amino acid is called a rate-limiting factor for that protein. For example, the tripeptide glutathione, a compound that forms an important part of the body's protective mechanisms, is made of the amino acids glutamic acid, glycine and cysteine. Glutamic acid and glycine tend to be plentiful in the diet, and can be easily interconverted. Cysteine is the rate-limiting factor for glutathione; the amount of cysteine in the diet will determine the amount of glutathione that can be manufactured by the body.

    Amino acids have a special role to play in brain nutrition, because all neurotransmitters are derived from amino acids or related compounds such as choline. Brain neurotransmitters, specifically, are biochemical keys to the workings of the mind. They are substances that perform chemical transmission of nerve impulses between neurons or between neurons and other cell types such as muscle. They work in the following way: an electric current (or action potential) travels down the length of a neuron, or nerve cell, until it reaches the synapse - a narrow gap between two cells. The incoming nerve impulse triggers the release of neurotransmitter (NT) molecules, which diffuse across the synaptic gap. The neurotransmitter molecules bind with receptor proteins embedded in the membrane of the post synaptic neuron and activate a physiological response. Excitatory neurotransmitters propagate a new action potential while inhibitory NT's inhibit the development of new action potentials.

    The amino acid precursors of neurotransmitters are able to cross the blood-brain barrier, a structural feature of brain anatomy that prevents many substances from contacting brain tissue. Thus, it is possible to influence brain metabolism (and therefore emotional states) through the mechanism of neurotransmitter synthesis. The enhancement of neurotransmitter production is one of the most exciting advancements to occur in the field of nutrition in modern times.

    A major portion of the amino acid requirement in humans is derived from the proteins in food. Successive proteolytic enzymes attack the peptide bonds, cleaving one amino acid at a time from the polypeptide chain. Ultimately, free amino acids as well as small peptides (especially dipeptides) are absorbed through the mucosal cells of the small intestine. The small peptides are then further hydrolyzed so that only free amino acids enter the liver and portal vein. This sounds like a fairly straightforward process. However, the presence of a particular amino acid profile in a certain food does not guarantee the assimilation of those amino acids when the food is ingested. There are three types of amino acids: acidic, basic and neutral; each of these classes has a different transport mediator. Therefore, there is competition for the carrier between any two amino acids in a certain class, both in the digestive tract and at the blood-brain barrier. Thus, the isolation of "Free-form" amino acids is an important aid to nutritional engineering. In many cases, the consumption of high potencies of a particular amino acid allows that nutrient to overwhelm the competition for absorption. The resulting increase in blood and tissue levels will yield the benefits conferred by that nutrient.

    The isolation of Free-form amino acids is an important advancement in the field of nutrition science. Amino acid supplements offer a broad range of choices to complement your nutritional program.



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    PYCNOGENOL ® - The Ultimate Antioxidant
    TopPreviousNext

    Date: June 04, 2005 02:04 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: PYCNOGENOL ® - The Ultimate Antioxidant

    Pycnogenol

    Pycnogenol® is a breakthrough in antioxidant protection that demonstrates how important natural nutrition can be for your health. Antioxidants are a class of biological molecules that function to scavenge and neutralize free radicals. Free radicals are molecules with unpaired electrons that cause damage at the cellular level, and which unfortunately are unavoidable. Antioxidants – the most famous of which thus far have been Vitamin C and Vitamin E – work to protect living tissue by neutralizing free radicals, thereby interrupting many of their harmful activities. Pycnogenol®, one of the most powerful antioxidants yet discovered, is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima. It is 20 times more potent an antioxidant than Vitamin C, and 50 times more so than Vitamin E.

    Free radicals are a real threat

    Uniquely vulnerable targets of free radical attack that require a regular supply of antioxidants just to maintain a basic level of function include fatty acids – especially those in cell membranes – and sulfhydral proteins, which form one of the most common types of chemical bonds found in biological organisms. The importance of these substances for overall health cannot be overstated, as they are critical components not only of tissues throughout the body, but most importantly, of the principal regulatory organs – the brain and liver – and every blood vessel. Free radical attack on fatty acids – known as lipid peroxidation – and related destruction of sulfhydral proteins can lead to diminished function of cell membranes and whole organs. This, in turn, can contribute significantly to decreases in quality of life.

    Free radicals are believed to be active in the development of cumulative damage to the system, as well as in many of the undesirable effects of aging. Free radicals are constantly being produced due to the natural intake of oxygen and generation of energy by the body’s cells. However, their production is heightened by pollutants such as tobacco smoke, alcohol, solvents, and oxidized cholesterol from foods. Therefore, health scientists suggest we may need to increase our intake of antioxidants either from foods or from supplements – such as Vitamin A and Beta Carotene, Vitamins C and E, Selenium, Cysteine, and now, Pycnogenol®.

    Potent antioxidant protection from nature - Pycnogenol®

    Originally discovered by renowned scientist Jacques Masquelier, Pycnogenol® is a natural 85% to 95% concentrate of proanthocyanidins extracted from the bark of the Maritime Pine. Proanthocyanidins are a special class of highly bioavailable, water-soluble bioflavonoids with unparalleled free radical scavenging activity. They readily cross the Blood-Brain Barrier to provide antioxidant protection to the central nervous system, and stay in the bloodstream for approximately 72 hours. Thirty years of sound European research shows that proanthocyanidins from Pycnogenol® are highly beneficial with no evidence of adverse effects, even after more than ten years of use. They also show no loss in potency after 12 years of storage.

    Better health for an active life

    As a potent antioxidant, Pycnogenol® is valuable for protecting the liver from free radical attack. Since the liver is the main detoxifying, nutrient-assimilating, and energy-generating organ of the body, this may mean more potential for activity in your life. Pycnogenol® may also aid recovery for athletes on strenuous workout regimes and in competition.

    Healthy capillaries through healthy collagen

    A major beneficiary of the protective actions of Pycnogenol® is collagen, the most abundant protein in the body. Collagen is responsible for maintaining the integrity of “ground substance,” the basic material in functional fluids, mucus linings, and connective tissue such as tendons, ligaments, cartilage, and most importantly, blood vessels linings. It is highly vulnerable to free radical attack, and a number of discomforting and depreciating processes are associated with its destruction. There is evidence showing that Pycnogenol® can provide remarkable support for the prevention of collagen destruction, and it has received much attention for its special affinity for capillaries, the smallest blood vessels. Pycnogenol® helps strengthen capillary linings in three key ways. First, Pycnogenol® functions to scavenge the free radicals that may compromise the integrity of collagen. Second, Pycnogenol® contains catechin, which is thought to stabilize collagen by forming hydrogen bonds and cross-linking collagen. Third, Pycnogenol® is Vitamin C-sparing, meaning it can fill in for C in a number of functions; this frees some Vitamin C – required for the synthesis of hydroxproline, a major structural amino acid of collagen – for use in building collagen. People who smoke and women who take oral contraceptives can reduce their heightened risk of Vitamin C depletion by taking advantage of Pycnogenol®’s Vitamin C-sparing activity.

    Look to Source Naturals® for 25 mg, 50 mg, 75 mg, & 100 mg tablets of this natural wonder!

    References

  • • Hagerman, A. and L. Butler. “The specificity of proanthocyanidin-protein interactions.” Journal of Biological Chemistry 256 (1981): 4494-97.
  • • Kuttan, R., et al. “Collagen treated with catechin becomes resistant to the action of mammalian collagenase.” Experienta. 37 (1981): 221-23.
  • • Masquelier, J. Natural Products as Medicinal Agents “Pycnogenol®s: Recent Advances in the Therapeutical Activity of Proanthocyanidins” (pp. 243-65). Stutgart, Germany: Hippokrates Verlag, 1981.
  • • Maunier, M.T., E. Duroux, and P. Bastide. “Free-radical scavenger activity of procyanidolic oligomers and anthocyanosides with respect to superoxide anion and lipid peroxidation.” Plantes Medicinales et Phytotherapie, 23.4 (1989): 267-74.



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    Muscle Mass - Reach Your Maximum Muscle Potential
    TopPreviousNext

    Date: June 04, 2005 09:49 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Muscle Mass - Reach Your Maximum Muscle Potential

    The serious athletes of today know how much it takes to fulfill their competitive goals: careful training, a strong will, and also the right kind of nutrition. Sports science now makes available key nutrients which help assure that strenuous workout regimes will show results. Results that are both nutritionally sound and dramatically visible, without the need for dangerous steroids or chemicals. MUSCLE MASS™ is such a state-of-the-art sports science formula.

    THE PURPOSE OF MUSCLE MASS ™ is to help translate distant goals for greater strength and power into quicker, awesome reality. It is the premier formula combining all essential nutrients known to maximize muscle development and optimize strength.

  • • Gamma Oryzanol: This safe, natural rice bran extract, heavily researched in Japan since the 1950s, is rightfully winning raves among athletes who have discovered its startling developmental properties.
  • • Ornithine: Celebrated by the Life Extension and Eat to Win books, this Free-form amino acid also has noticeable building effects, and in addition, adds tone and definition to the results.
  • • Lipotropic Factors: Helping to turn excess fats into energy quickly are LCarnitine, L-Methionine, Choline, and Inositol.
  • • Branched Chain Amino Acids: L-Leucine, L-Isoleucine, and L-Valine protect muscles during stressful exertion by providing extra nitrogen and energy.
  • • Special Herbs: Chosen from both the American and Chinese herbal traditions for their building and energizing qualities are Saw Palmetto, Ginseng, and others.
  • • Co-Nutrients: For the oxygenating, transporting and catalyzing contributions are included Glycine, B-5, B-6, Betaine, and Licorice Root.

    In sum, all these balanced, cutting-edge factors combine to assist you in meeting the challenges you’ve set for your body. Power, endurance, strength, tone, and the winner’s circle are now closer.



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    Glycerylphosphorylcholine
    TopPreviousNext

    Date: May 24, 2005 10:05 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Glycerylphosphorylcholine

    Dietary supplement

    Abstract A dietary supplement for promoting healthy hormonal balance in adult human subjects, and especially in elderly subjects, that comprises a secretagogue for stimulating the release by the pituitary, and the conversion by to Insulin-Like G, in combination with 7-keto dehydroepiandosterone (7-keto DHEA). The dietary supplement also includes other interacting ingredients for delivering antioxidants for retarding damage at the cellular level caused by the presence of free radicals, and natural herbs for promoting physiological health.

    Other References Jamieson, J. et al., "The Role of Intermediates as an Alternative to High Injections," American College for Advancement in Medicine, (Oct. 30, 1997).

    Claims

    What is claimed is:

    L-lysine monohydrochloride, glycine, and gamma aminobutyric acid.

    L-dopa

    7-keto dehydroepiandrosterone

    resveratrol

    L-arginine

    acetyl-L-carnitine.

    L-glutathione.

    n-acetyl cysteine



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    Spectro 3 and Spectro Multivitamin
    TopPreviousNext

    Date: May 21, 2005 10:20 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Spectro 3 and Spectro Multivitamin

    Spectro ®

  • Considered by many to be the premier multivitamin/mineral supplement.
  • Complete vitamin
  • Complete mineral
  • Digestive enzymes
  • Herbs
  • Comes in a large range of sizes.

  • Spectro Iron Free multivitamin 100ct

  • Spectro Iron Free Multivitamin 250ct

  • Spectro Iron Free Multivitamin 360ct

  • Spectro 3 multivitamin 180ct

  • Spectro 3 Multivitamin 90ct

  • Spectro 3 Iron Free multivitamin 180ct

  • Spectro 3 Iron Free multivitamin 90ct

  • Spectro Smoothie drink mix 720g

  • Spectro Vegetarian multivitamin 90ct

  • Spectro Vegetarian Multivitamin 180ct



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    LACTOSE INTOLERANCE AND ACIDOPHILUS ...
    TopPreviousNext

    Date: May 18, 2005 06:21 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: LACTOSE INTOLERANCE AND ACIDOPHILUS ...

    Lactose intolerance is a common condition. It occurs as the body is not able to digest the milk sugar found in dairy products. Symptoms can include stomach cramps, gas, diarrhea, indigestion and general stomach discomfort. Some individuals have a difficult time digestive and assimilating milk products. Acidophilus has been added to some commercial brands of milk products to aid in digestion. The addition of Lactobacillus acidophilus has been found to help improve lactose absorption and reduce the problems of some people with lactose intolerance. The acidophilus contains an enzyme that may be missing in individuals with lactose intolerance. This enzyme is responsible for changing the lactose to lactic acid. One study found that the addition of acidophilus to low fat milk improved the lactose absorption by four times in lactose sensitive individuals. The results were better over a week period and lasted for a week after the dis- continuation of the acidophilus milk.17

    15111

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    related links
    TopPreviousNext

    Date: May 18, 2005 06:17 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: related links

    SN0955

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    Bee Propolis
    TopPreviousNext

    Date: May 12, 2005 05:14 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Bee Propolis

    Propolis



    Bees create propolis by collecting a resinous sap from trees and then mixing it with wax back at the hive. They use this material much the way people use caulk: to seal their homes. Chemically, propolis is exceedingly complex and contains a rich variety of potent terpenes and benzoic, caffeic, cinnamic,and phenolic acids. It's also high in flavonoids, which by themselves may account for many of the benefits attributed to propolis-and some researchers refer to propolis as a type of flavonoid.


    One of the most significant medical journal articles described how the caffeic acids in propolis and honey might prevent colon cancer, which kills some 60,000 Americans each year. Chinthalapally V. Rao, Ph.D., of the American health Foundation, Valhalla, N.Y., reported in Cancer Research (Sept.15,1993; 53:1482-88) that these caffeic acids prevented the formation of precancerous tissue in rats after they were exposed to cancer-causing chemicals.


    Most medical articles, however, still point to the value of propolis as a powerful, natural antibiotic. That doesn't mean eating propolis will let you throw away your antibiotics - only that you may not need them quite as often.


    Why would bees need substances with broad antibacterial and antiviral properties? Any beekeeper will tell you the answer. Bees are very susceptible to bacterial and viral infections, which can destroy hives the way the bubonic plague ravaged Europe in the 17th century.


    Two medical journal articles document the activity of propolis specifically against Staphylococcus aureus, the bacterium that causes dangerous and often deadly surgical infections, blood poisoning, and a type of pneumonia. Five to 10 percent of all patients hospitalized in the United States develop such infections, and S. aureus has become resistant to all but one pharmaceutical antibiotic.


    In a Chinese study, researchers found that extracts of propolis - specifically, sinapic, isoferulic, and caffeic acids - inhibited the growth of S. aureus (Qiao Z, China Journal of Chinese Materi Medica, Aug. 1991;16:481-2). A European study reported that ethanol extracts from propolis had a "marked synergistic effect" on the anti-staph activity of two antibiotics, streptomycin and cloxacillin, and a moderate effect on several others (Krol W, Arzneimittel-Forschung, May 1993;43:607-9).


    Another scientific investigation discovered that propolis inhibited the activity of several streptococcal bacteria species that cause dental caries.Japanese researchers reported that propolis-fed laboratory fats had far fewer caries than those given a regular diet. Propolis protected specifically against Streptococcus mutans and several other strep species (Ikeno K, Caries research, 1991;25:347-51). These strep species are closely related to the germ that causes strep throat.


    Propolis works against bacteria in several ways. One study reported that it prevented bacterial cell division and also broke down bacterial walls and cytoplasm, which is how some prescription antibiotics work (Takaisi-KikuniNB, Planta Medica, June 1994;60:222-7).


    Perhaps more remarkable is that propolis acts against viruses, which antibiotics do not. A number of medical journal reports have discussed the role of propolisin fighting upper respiratory infections, such as those caused by the common cold and influenza viruses (Focht J, Arzneimittel-Forschung, Aug. 1993;43:921-3). Other investigators have reported that the cinnamic acid extracts of propolis prevent viruses from reproducing, but they worked best when used during the entire infection (Serkedjieva J, Journal of Natural Products, March 1992;55:294-302).


    Underpinning many of the benefits of propolis is that some of its components,like the flavonoids and ethanols, function as antioxidant Free-radical scavengers. A study published in the Journal of Ethnopharmacology (Jan. 1994;21:9-13)noted that some of the antioxidant phenols in propolis functioned similarly to vitamin E. In another article, researchers described that propolis had anti-inflammatory properties and that it could also prevent blood clots(Drugs Under Experimental & Clinical Research, 1993; 19:197-203).

  • Bee Propolis 60ct
  • Propolis 500mg 60 caps
  • Propolis Plus from Solaray
  • Propolis Tincture 1 fl.oz.
  • Propolis Thyme Tincture 1 fl.oz.

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    Guggul – New Benefits for Heart Health
    TopPreviousNext

    Date: May 11, 2005 09:00 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Guggul – New Benefits for Heart Health

    Gum Guggul–New Benefits for Heart Health from an Age-Old Herb

    by Richard Conant, L.Ac., C.N.

    The 1990's have seen a growing interest in herbs from India's ancient Ayurvedic tradition. One Ayurvedic herb in particular, "gum guggul," stands at the forefront, thanks to its rather remarkable benefits for the heart and cardiovascular health. A relative of myrrh and frankincense, gum guggul is a resin tapped from India's Commiphora mukul tree. Known more commonly in the Far East as simply "guggul," the herb has proven to be one of the most effective natural cholesterol-lowering agents ever discovered. Cholesterol reductions with guggul can be twenty percent or higher, and the herb also raises HDL, the more beneficial form of cholesterol. Studies also show guggul may help prevent atherosclerosis, by retarding the formation of fatty, cholesterol-laden deposits in blood vessel tissues.

    Recent research on guggul has revealed that guggul also blocks the oxidation of LDL cholesterol, by acting as an antioxidant. LDL, which carries cholesterol from the liver to the rest of the body, is generally regarded as a key element in the development of atherosclerosis. But only when it is oxidized by free radicals does LDL accumulate in arteries. It its unoxidized or "native" state, LDL is more or less benign. Checking LDL oxidation is vital to keeping blood vessels free of plaque.1 (This is one of the major reasons why antioxidants are so important.) Guggul, by both lowering blood cholesterol and acting against LDL oxidation, now stands out as one of the world's most valuable herbs for heart health.

    Guggul first caught the attention of the scientific world in1966, thanks to an Indian medical researcher who submitted a doctoral thesis on gum guggul.2 Her interest had been kindled by references to the herb in a centuries-old Ayurvedic text. Apparently, poor cardiovascular health and atherosclerosis were a problem back then just as they are today. Translated from Sanskrit, this text describes, in elegant detail, a condition called "coating and obstruction of channels." The cause, according to the ancient writers? Faulty metabolism due to overeating of fatty foods and lack of exercise. Death was said to be the end result of leaving this condition uncorrected. The recommended treatment plan emphasized diet and herbs, chiefly gum guggul.3

    References to guggul in ancient literature actually go back even farther. The herb is mentioned in the Vedas, the holy scriptures of India believed to be anywhere from 3,000 to 10,000 years old. One stanza is translated as follows: "Disease (consumption) does not afflict and the curse never affects whom the delicious odor of the healing Guggul penetrates (spreads). The diseases also flee away in all directions from him like horses and deer, O Gugulu! Either born from Sindhu or from the sea. I chant your name for the removal of diseases."3

    Struck by the obvious similarity between "coating and obstruction of channels" and atherosclerosis, the Indian researcher decided to study gum guggul's effect on blood fats in rabbits. Over a two-year period, the animals were fed hydrogenated vegetable oil to artificially raise their cholesterol levels. Guggul was administered to one group of rabbits, while the rest served as controls. At the end of the study the rabbits given guggul had normal cholesterol and blood lipid levels. Their arteries showed no fatty streaks or plague deposits. This caught the attention of the Indian scientific community, and numerous clinical trials ensued, both on animals and humans. In study after study, guggul consistently produced substantial reductions in cholesterol and triglyceride levels, while raising HDL.

    The active ingredients in guggul are a group of natural plant sterols. Among these, substances called "guggulsterones" are the most important ingredients for the cholesterol and blood fat lowering properties of guggul, with the other sterols acting as a synergistic supporting cast.4 A number of mechanisms are suggested, although not definitely proven, for how the herb works; these include reducing the synthesis of cholesterol in the liver, enhancing cholesterol removal from the gut, stimulating thyroid function and increasing the number of receptors in the liver for uptake of LDL.3,5

    Guggul extracts are now standardized for guggulsterone content. The herb naturally contains about 2 percent guggulsterones. Quality extracts contain a minimum of 2.5 percent, which assures the user is getting a product potent enough to produce results. Since the late 1980's clinical trials have used the standardized extract.6,7,8 The product is readily available in the U.S.

    The ability of guggulsterones to prevent oxidation of LDL was discovered in a 1997 study done by scientists at the Central Drug Research Institute in Lucknow, India.9 This study sheds light on how guggul works against "coating and obstruction of channels." Remember that oxidized LDL forms the plaque that coats and eventually obstructs blood vessels. The researchers mixed LDL from human blood with a free radical promoting agent, either alone or in combination with guggulsterones. Samples were then analyzed for the presence LDL oxidation byproducts. The results showed that guggulsterones strongly protect LDL from being oxidized. Guggulsterones block the formation of hydroxyl radicals, a potent type of Free-radical that attacks cell membranes.

    Guggulsterones may also help keep the heart muscle itself healthy. When the heart muscle is deprived of oxygen, a condition known as "myocardial ischemia," it can be severely damaged by free radicals. The body tries to counter this with SOD, a key enzyme present in cells that neutralizes free radicals. SOD levels are significantly reduced in damaged heart tissues. Guggulsterones have been found to reverse this decrease by more than two-fold.10

    Like the writer of that age-old verse found in the Vedas, contemporary herbalists hold gum guggul in the highest regard. Backed as it is by scientific research linked to centuries of traditional use, gum guggul has a bright future as a natural resource for maintaining normal cholesterol and blood fats, and for protecting heart health.

    References

    1. Heinecke, J.W. Free radical modification of low density lipoprotein: mechanisms and biological consequences. Free Radical Biology & Medicine 1987;3:65-73.

    2. Satyavati, G.V. Effect of an indigenous drug on disorders of lipid metabolism with special reference to atherosclerosis and obesity (Medoroga) M.D. thesis (Doctor of Ayurvedic Medicine). Banaras Hindu University, varanasi, 1966.

    3. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.

    4. Dev, S. A modern look at an age-old Ayurvedic drug-guggulu. Science Age July 1987:13-18.

    5. Singh, V. et. al. Stimulation of low density lipoprotein receptor activity in liver membrane of guggulsterone treated rats. Pharmacological Research 1990;22(1):37-44.

    6. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.

    7. Agarwal, R.C. et. al. Clinical trial of gugulipid-a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.

    8. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.

    9. Singh, K., Chandler, R. Kapoor, N.K. Guggulsterone, a potent hypolipidaemic, prevents oxidation of low density lipoprotein. Phytotherapy Research 1997;11:291-94.

    10. Kaul, S. Kapoor, N.K. Reversal of chnages of lipid peroxide, xanthine oxidase and superoxide dismutase by cardio-protective drugs in isoproterenol induced myocardial necrosis in rats. Indian Journal of Experimental Biology 1989;27:625-627.

  • Solaray Guggul 60ct
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  • Doctors Best Guggul "Guggulow" 90ct


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