(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1461)

Date: February 25, 2007 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Neurological Health and CoQ10

Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.

Q. Isn’t CoQ10 a supplement for heart health?

A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.

Q. How does CoQ10 affect brain health?

A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.

The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.

The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.

Q. What is the blood-brain barrier and why is it important?

A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.

Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.

Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.

Q. If CoQ10 is made in the body, why take supplements?

A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.

Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.

Q. How does CoQ10 help people with Parkinson’s disease?

A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.

A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.

Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.

The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.

The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.

Q. What were the results of clinical research on Huntington’s Disease?

A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.

Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.

Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.

Q. What other diseases could benefit from CoQ10 supplementation?

A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.

In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.

ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.

Q. Can taking CoQ10 prevent neurodegenerative disease?

A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.

Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.

Q. How much CoQ10 should I take?

A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.

CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

Q. What should I look for in a CoQ10 supplement?

A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.

Conclusion

CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.

All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.

--
Buy Coenzyme Q10 (COQ10) at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459)

Date: August 21, 2006 05:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What are you really Getting?

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1353)

Date: July 26, 2006 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of taking Vitamin C Daily

Vitamin C benefits

1. maintain normal connective tissue and wound healing.

2. help strengthen bones.

3. Vitamin C is a Cofactor in the production of epinephrine (adrenalin).

4. Vitamin C helps in the production of Bile acids for digestion.

5. Vitamin C helps in the production of Thyroxin (Thyroid hormone).

6. helps in the absorption of Iron.

7. aids in amino acid metabolism.

8. helps strengthens the body during infection.

9. helps counter oxidative stress.

10. may help strengthen veins and aid in diabetic retinopathy.

11. Vitamin c may help reduce the binding of glucose to proteins in diabetics.

12. in large doses Vitamin C has shown to have an antihistamine effect and may be helpful with asthma and allergies.

13. Vitamin C is needed for the synthesis of L-Carnitine, L-Carnitine helps transport fat into cells to burn as energy.

1000mgs of vitamin C each day helps keep the doctor away ;)

for proper vitamin C intake try Alacer Emergen C drinks...

Also try: Now Vitamins for great Vitamin C!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1330)

Date: June 19, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The healing power of borage oil

Borage oil, extracted from the seed of the blue, star shaped borage flower, is gaining much attention by alternative health practitioners and main stream medicine alike for its profound medicinal properties. Whereas the oil is getting all the redit, it is actually the oil’s active component, gamma linoleic acid (GLA), which has drawn the interest of researchers. The majority of the early studies done on GLA, dating back to the late 1940’s, were conducted with the oil of evening primrose. For rezones cited in the title, more bank for the buck, borage seed oil is now thought to be s superior source of GLA compared to evening primrose oil. Other plants forms and food concentrates that contain appreciable amounts of GLA include black currant seed oil and spirulina.

Why GLA Supplementation?

A body with healthy biochemistry has the ability to produce GLA from the most essential fat linoleic acid. Linoleic acid is found most abundantly in the omega 6 family of oils, including safflower, sunflower, and corn oil. While it has been estimated that a majority of Americans and Europeans consume far to many omega 6 fatty acids in proportion to the beneficial omega 3 fatty acids (by approximately 10:1). Most biochemists agree optimal ratio of omega 6 to omega 3 fatty acids should be approximately 1:1. Despite the obvious over consumption of omega 6 oils rich in linoleic acid, some individuals lack the ability to convert linoleic acid to the much needed GLA.

As is the example with many of our modern day nutrient deficiencies, the adulteration of our food supply by today’s processing methods has much to do with the faulty fat metabolism suffered by many. A prime example is the hydrogenation process utilized to convert liquid polyunsaturated oils into semi-solid, altered saturated fats for use as margarine and commercially processed foods. Hydrogenation is accomplished by subjecting the oils to temperatures in excess of 250 C, and bombarding them with hydrogen ions in the presence of the heavy metal nickel, which irreversibly changes the chemical structure of the fatty acid molecule from a healthful “cis” configuration to a dangerous “trans” configuration. When these products are eaten in excess they are known, in some cases, to block the enzymatic conversion of linoleic acid to GLA. In addition to the damaging effects of hydrogenation, certain essential fatty acid nutrient cofactor deficiencies may exist to further complicate the conversion. Vitamins pro-A, A, C, E, B-2, B-3, B-6, pantothenic acid, B-12 biotin and the minerals calcium, magnesium, potassium, sulfur and zinc are all involved in essential fatty acid (EFA) metabolism.

Particular interest should be given to those afflicted with diabetes, cystic fibrosis, asthma, alcoholism, multiple sclerosis. For a myriad of reasons, including cofactor deficiencies, these individuals lack the enzymatic ability to convert linoleic acid to GLA and must obtain a direct source of GLA for proper hormonal regulation. In addition, excessive consumption of animal fats containing acachidonic acid competes for the same metabolic pathways occupied by GLA, thus minimizing its biological action.

These potential negating effects can simply be diverted to consuming a food source or supplement containing GLA which bypasses any previously necessary enzymatic conversion and floods the metabolic pathways with beneficial GLA. Nutrient deficiency should also be addressed. Here lies the true power of GLA.

Prostaglandins, biochemical regulators

Whereas GLA is the power, the prostaglandins deliver the punch in this biological equation. Just as linoleic acid is normally converted to GLA, GLA is further converted into the prostaglandin E1 (PGE1). Many of the benefits derived from GLA supplementation are a result of the hormonal regulatory action of the prostaglandins. Just like the “parent” precursors they are made from, the hormone-like prostaglandins orchestrate a host of important biochemical activities. Their general regulatory effects include the control of arterial muscle tone, sodium excretion through the kidneys, blood platelet “Stickiness,” inflammatory response and the immune function, just to name a few. The list may be endless as scientists continue to discover the regulating effects of prostaglandins. One way in which GLA has shown to decrease the probability of allergic and inflammatory conditions is by competing with arachidomic acid, which when left unchecked may potentiate a hyperimmune response.

Healing Power

As a result of the powerful regulating effects derived from the conversion of GLA to healthful prostaglandins, borage oil and other GLA supplements have shown to be beneficial in the treatment and relief of many classic and modern day health problems. The disease of diabetes, cystic fibrosis, asthma, multiple sclerosis are thought to be helped by bringing about a balance in an otherwise faulty fatty acid metabolism. According to a study released in the journal diabetes care, supplementation with GLA has shown promise in the reversal of diabetic neuropathy (a condition where the nerves degenerate and symptoms of pain and numbness follow). The study concluded that all diabetics should be considered for dietary protocol of GLA. Other conditions shown to benefit include high blood pressure, high cholesterol, skin conditions, arthritis, allergies, weight loss, improved behavior of hyperactive children and increased strength of hair and nails. Cited in the book, Super Nutrition For Menopause, written by the renowned nutritionist Ann Louise Gittleman, is one of the most popular applications of GLA supplementation in the relief of menstrual pain. Sufferers use a maintenance does up to the seventh day prior to menstruation, then double the dose for the duration of their menstruation. Dietary restrictions of meat, dairy and eggs during this time has also shown to compliment this regiment. Many would agree with Ms. Gittleman’s credo in allowing mother nature to cure our ails before relying on synthetic drugs which often come with side effects.

More Bang for the Buck

Now comes the challenge of acquiring a GLA supplement suited to meet your needs. With the help of the information below you may maximize your desired result while at the same time stretching your dollars. Lets take a look at the facts. We will limit out narrative to the tree most popular forms of GLA supplementation: 1) borage oil, 2) evening primrose oil and 3) black current seed oil. Potency is an important factor, as the higher the GLA content per gram, the more likelihood of greater biological activity. Borage oil contains 24% GLA, or 240mg per 1000 mg capsules. Black current seed oil contains 18%, or 180mg per 1000 mg capsule and evening primrose oil contains 10% GLA, or 100mg per 1000 mg capsule. While black currant seed may appear to run a close second to borage and have a slight edge on evening primrose, it contains a potent GLA inhibitor and should be considered last on the list. equally, if not more important than potency, is purity. Make it a practice not to purchase any oil product unless full disclosure of the method of extraction is printed on the label. If it is not, you may assume that the oil has been extracted in one of the following ways. Unfortunately, the popular use of the chemical hexane to extract oils is not required for disclosure. This method employs submerging cracked seed in a gasoline like substance (Hexane) and then slowly allowing it to evaporate off yielding 90% oil recovery. This is the most common method used to extract evening primrose oil because of the incredibly small, hard seed and low oil content. The second creative ploy is the claim that the oil has simply been extracted by a new high-tech method called supercritical fluid extraction (SCFE). This process “pregrinds” the seeds then subjects them to pressures of 6000 – 10000 psi in the presence of the gas CO-2. Under such intense pressure CO-2 gas becomes a liquid in which the seeds are submerged, ultimately yielding a 95% oil recovery. Look for oils that are labeled as “expeller pressed” without the damaging effects of light, heat and oxygen. The products should be contained in opaque (light resistant) bottles to protect them from the damaging effects of light. Optimally, you should find them in the refrigerated section of your local health food store. Due to the higher percentage of oil contained in the borage seed, as compared to evening primrose and black current, borage is typically priced well below the others making it the most potent and economical choice. All things considered an expeller pressed borage oil, contained in an opaque plastic bottle, may provide you the absolute best source of unadulterated GLA supplementation.

One company that provides such a product and always fulfills the quality requirements listed is Barlean’s Organic Oils. Their organic flax oil and borage oils are available at VitaNet.

--
Buy Barlean's Organic Oils at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1316)

Date: March 27, 2006 06:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Now Foods

Now Foods Vitamins Discount Prices

If there’s one truth to be told about the natural products industry, it is this. We will never have a shortage of companies claiming to be the best. It happens so often in fact, that distinguishing the quality from the questionable has become an exhausting task all in itself. After all, making claims is easy. What’s challenging, however, is supporting these claims with something concrete.

As no stranger to recognition, NOW takes pride in every honor that is bestowed upon us. And yes, over the past year, we have been blessed in many ways. Nothing, however, can match the sense of reward that comes from having our efforts, values and commitment to human wellness acknowledged by our peers, colleagues and valued customers. It is with the most sincere gratitude that we are once again able to share these with you.

Vitamin Retailer Magazine’s 2005 Vity Awards Every Spring, Vitamin Retailer Magazine recognizes the most outstanding dietary supplements, and honors the recipients with a Vity Award. The winning products are selected based on a number of criteria. This year, three NOW products were awarded 1st place honors.

The first was presented in recognition of our MSM 1000 mg. This marks the third consecutive year that we’ve watched our MSM excel in this category. Next was the award for Vitamin E, which went to our Natural Vitamin E-400 mixed tocopherol formula. Like MSM, this was also awarded 1st place st place for the third year in a row. Finally, the award for “Best Calcium”, which was given to our Calcium Citrate. With the calcium category regarded as one of the most competitive, taking top honors is an accomplishment that we’re all very proud of. Whole Foods Magazine Natural Choice Winner Best Sports Supplement

It should come as no surprise to anyone that there are literally hundreds of protein formulas available. When it was announced that our line of Whey proteins had earned the title of “Best Sports Supplement” from Whole Foods Magazine, we were truly honored to be selected as one of their Natural Choice winners.

Each year, Whole Foods Magazine evaluates hundreds of products, selecting only those that meet their demanding standards. Our Sports division has worked tirelessly to perfect our Whey proteins, and this award is a true testament to the efforts they have put forth. NOW is one of the very few companies that offers a line of 100% natural proteins, free of artifi cial sweeteners. Accordingly, this is an honor that we’re especially proud of. Nutrition Business Journal’s Lifetime Leadership Award, Elwood Richard

Nutrition Business Journal recently honored NOW founder Elwood Richard, with their prestigious Lifetime Leadership Award. Mr. Richard has been an active member of the natural products business since 1960 and is a strong advocate for both science and quality. He co-founded the NNFA standards committee, and sponsors industry organizations such as Citizens for Health, NNFA, ABC, AOAC and AHPA among others. His hard work, vision and commitment have inspired our entire organization

in supporting independent retailers, producing quality products and taking proactive measures towards environmental preservation.

Nutrition Business Journal’s Business Achievement Award, Environment of Sustainability In addition to the award presented to Elwood Richard, NOW was also the recipient of the NBJ Business Achievement Award for Environment of Sustainability. This honor is presented to businesses who have consistently participated in both internal and local initiatives to make positive environmental impacts. Notably, our recycling program has reduced waste output by over 50%. NOW FOODS Vitamins also conducts employee training programs, supports community conservation efforts and hosts volunteer workdays to plant vegetation, remove litter and control lakeside erosion in a local forest preserve. These actions have earned us a number of community service awards from several local recreation organizations. Finally, we help support environmental organizations, including The Nature Conservancy and World Wildlife Fund.

AOAC adopts NOW Glucosamine Method

NOW Foods’ glucosamine HPLC method has passed the AOAC’s 2-year validation process to become the fi rst offi cial method for testing the standards of this popular joint health ingredient. It was selected by the expert review panel in April of 2003 as the “best method for further laboratory validation”. It will be published in the Journal of AOAC International and become available to the industry this summer, 2005. “Having NOW’s method for glucosamine become the offi cial AOAC method is a testament to the expertise of our staff, our focus on the science, and our commitment to quality,” said Michael Lelah, technical director of NOW Foods.

DuPage County Forest Preserve District’s Shooting Star Award.

The DuPage County Forest Preserve District of Illinois recently presented NOW Foods their Shooting Star Award at their annual Forest Preserve District volunteer banquet. This award recognizes the long-term efforts that our entire organization has made in order to improve and support the quality of the East Branch Forest Preserve in Glendale Heights, IL. This is also the fi rst time that the District has given this award to a company. As the primary recipient, we look forward to furthering our environmental efforts.

Recapping our 2004 Achievements

Eight 1st Place Vity Awards, from Vitamin Retailer Magazine

United States Department of Commerce Excellence in Export Achievement Award

Nutrition Business Journal’s Effort on Behalf of Industry Award Consumerlab.com Top Rated Brand in Health Food Stores based on Customer Satisfaction Natural Nutritional Foods Association (NNFA) Crusader Award, Elwood Richard Vitamin Retailer Magazine Manufacturer of the Year (2003)

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1241)

Date: February 17, 2006 06:29 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: California Proposition 65 (Prop 65) and Progesterone Cream Warnings

Scientific Safety Information on Progesterone

California Proposition 65 (Prop 65) and Progesterone Cream Warnings Amy Kosowski, M.S., LDN

Prop 65: What is it?

Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986 , was enacted as a ballot initiative in the state of California in November of 1986. The Proposition was intended by its authors to protect California citizens and the State's drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals 1.

Proposition 65 requires the Governor to publish, at least annually, a list of chemicals “known to the state to cause cancer or reproductive toxicity .” Progesterone, as well as other human hormones, appear on this list 1. Set forth below is the information that formed the bases for the addition of progesterone to the Prop 65 list by the California Office of Environmental Health Hazard Assessment (“OEHHA”).

Prop 65 and Progesterone - Perspective

In August of 2004, OEHHA published a document stating the rationale for the addition of Progesterone to the Prop 65 list 2. This document is a review of human, animal, and in vitro studies that used progesterone, synthetic progestins, and other progestagens (progesterone-like compounds). Experimental data from the use of all of these compounds were mixed together, along with data from studies using other steroid hormone derivatives (mainly synthetic estrogens) and many different methods of administration.

Although this review covered the existing scientific literature on progesterone and its many derivative compounds, there are many problems with the type of data analysis that was employed.

First, progesterone is endogenous to humans and necessary for bone and reproductive health while progestins and other synthetic progestagens are not. Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are usually much stronger and more likely to cause abnormal physiologic responses 3, 4. Furthermore, the majority of the studies concerning the health effects of these progesterone derivatives involved combinations with synthetic estrogens 2-4.

There were very few studies mentioned in the 2004 document that used exclusively bio-identical progesterone (the kind found normally produced by humans as well as that used in progesterone creams), and those studies that did were at supra-physiologic doses (very high). The doses of progesterone ranged from 10-1000 times the dose usually recommended by manufacturers of progesterone creams 2, although in a few cases, the doses were closer to the recommended dosages.

The route of administration of progesterone is also at issue. All of the studies cited in the OEHHA document used either oral, injected, or suppository forms of hormones; none was conducted using transdermal creams. This is an important consideration because hormones absorbed through the skin are metabolized differently than hormones that are administered via other routes 5, 6.

Putting it Together

While the OEHHA Prop 65 reference document on progesterone 2 is a broad survey of the published scientific literature examining the potential effects of the pharmaceutical use of progesterone and its synthetic derivatives, it is not clear at all that these effects would be seen with the use of low-dose progesterone creams.

The OEHHA Prop 65 progesterone document evaluates a broad range of information regarding progesterone and synthetic materials that are not natural progesterone. The conclusion reached was not challenged, and it is on that basis that progesterone creams now carry the Prop 65 warning.

References:

1 California OEHHA Web Site: //www.oehha.ca.gov/prop65/p65faq.html .

2 Reproductive and Cancer Hazard Assessment Section, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency (2004) Evidence on the developmental and Reproductive Toxicity of Progesterone.

3 Campagnoli C, Abba C, Ambroggio S, Peris C (2005) Pregnancy, progesterone and progestin in relation to breast cancer risk. J Steroid Biochem Mol Biol 97(5):441-450.

4 Campagnoli C , Clavel-Chapelon F , Kaaks R , Peris C , Berrino F (2005) Progestins and progesterone in hormone replacement therapy and the risk of breast cancer. Steroid Biochem Mol Biol 2005 96(2):95-108.

5 de Lignieres B, Dennerstein L, Backstrom T (1995) Influence of route of administration on progesterone metabolism. Maturitas 21:251-257.

6 Gompel A, et al. (2000) Progestins were also proapoptotic in normal as well as in hormone-dependent breast cancer cells. Steroids 65(10-11):593-598.

7 Bu SZ ( 1997) Progesterone induces apoptosis and up-regulation of p53 expression in human ovarian carcinoma cell lines. Cancer 79(10):1944-50.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1224)

Date: January 03, 2006 08:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3 Fish Oils “Super Supplement of the Sea”

• Enteric Coated Molecularly Distilled Omega-3
• PURIFICATION METHOD Molecularly distilled as pharmaceutical DHA 250 mg Softgels
• PURIFICATION METHOD Molecularly distilled and purifi ed MaxEPA 1000mg Gels
• PURIFICATION METHOD Advanced fi ltration via active carbon treatment Omega-3 1000mg, 180/120
• PURIFICATION METHOD AAT (Advanced absorbent technology) SuperEPA 1200mg 360/240
• PURIFICATION METHOD AAT with vacuum molecular (MD) distillation Super Omega 3-6-9 1200mg
• PURIFICATION METHOD Advanced absorbent technology Molecularly Distilled Lemon Liq.
• PURIFICATION METHOD Molecularly distilled as Pharmaceutical

References
1.) Vanderhaeghe L, Karst K, Healthy Fats for Life; Quarry Healthy Books. 2003
2.) Stoll AL, Severus WE, Freeman MP, et al. Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Arch General Psychiatry. 1999
3.) Ascherio A, Rimm EB, Stampfer MJ, et al. Dietary intake of marine n-3 fatty acids, fi sh intake, and the risk of coronary disease among men. New England Journal Med. 1995
4.) Challem J, The Infl ammation Syndrome; John Wiley and Sons Publishing. 2003
5.) Giampapa R, Pero R, Zimmerman M, The Anti-aging Solution; John Wiley and Sons Publishing, 2004
6.) Croft J, Health from the Seas, Freedom from Disease; Vital Health Publishing. 2003

*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1153)

Date: December 30, 2005 06:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: D 1000IU New Peppermint Flavor "D" Lightful taste

• Once daily formula in a refreshing, tiny peppermint flavored chewable with 1000IU Vitamin D.
• Vegetarian and naturally sweetened with Xylitol
• Consuming adequate Vitamin D is especially important for people who have reduced exposure to sun, particularly buring winter months.
• It is suggested that people aged 22 to 30 make more vitamin D than people aged 62 to 80 after being exposed to the same amount of sunlight.

Enjoy healthier bones and skin with Kal's new Vitamin D 1000IU Chewables.

Supplement Facts: Serving Size: 1
Vitamin D (as Ergocalciferol)(D-2) - 1000IU

Other Ingredients: Xylitol, Stearic ACid, Peppermint Flavoring, Lecithin (SOY) and Tocopherol (SOY).

--
Buy Vitamin D at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1134)

Date: December 27, 2005 05:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin C FAQ's

Vitamin C FAQ's

What is Calcium Ascorbate?

Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.

What does Calcium Ascorbate do?

Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.

Is this a necessary vitamin or can our bodies make enough to satisfy our needs?

Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.

What is the function of the Citrus Bioflavonoids?

Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.

Why are there color variations in your different Vitamin C products, and are they safe to take?

Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.

Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.

Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.

NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.

Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1099)

Date: December 27, 2005 09:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Effer-C NUTRITION YOU CAN DRINK

Effer-C NUTRITION YOU CAN DRINK 1000 mg of Vitamin C Per Serving Helps Restore Vital Electrolytes Includes CoQ10 and Alpha Lipoic Acid High in Energy-Producing B Vitamins 4 Great Tasting Flavors Vitamin C (ascorbic acid) is unquestionably one of life’s most important nutrients. Everyday we unknowing rely on it to help protect cells, produce energy, repair tissue and replenish lost electrolytes. Ironically, humans are just one of a handful of living creatures unable to produce our own supply of this vital nutrient. In fact, your dog can naturally manufacture upwards of ten times the amount of vitamin C that you might obtain in an entire day from food. To make matters worse, vitamin C can be a terribly stubborn nutrient. Not only are we incapable of producing it, but getting adequate amounts from the diet is a task all in itself. Today’s typical diet has become just that, typical. The convenience of fast food, sodium-rich snacks and over-processed heart bombs has reduced our once healthy society to a scrambling cluster of time-pressed professionals who’ve somehow forgotten what it’s like to actually prepare balanced, nutritious meals. This makes obtaining the nutrients we so desperately need, next to impossible. As if that wasn’t enough, vitamin C has a short halflife. Half lives measure the amount of time that it takes for one-half of a nutrient to be depleted from the bloodstream. In the case of vitamin C, it has a half life of just 30 minutes. For the sake of argument, let’s assume that your 7:00 AM breakfast includes an orange that contains a modest 70 mg of vitamin C. By 8:00, you’re left with only 35 mg. By 9:00, a mere 17 mg. And by the time lunch rolls around, you’ll be lucky to have any vitamin C in your system at all. This should be of great concern to anyone who doesn’t carry a bushel of oranges around at all times. Because aside from the fact that the body rapidly depletes its reserve of vitamin C, it also depends on what remains to carry out an long list of biological tasks. When it’s not there, everything suffers - energy, metabolism, immune response, cartilage integrity and so on. So how does one contend with this taxing concoction of unceasing stress, high-throttle lifestyle, endless toxins and pathetic dietary habits? It’s actually much simpler than you might imagine. Thanks to new technology in the nutritional sciences, getting the C you need no longer requires carrying around bottles of capsules or huge sacks of fruit. Effer-C™ from NOW® is an effervescent vitamin C unlike any other, and was designed to quickly replenish the vital electrolytes needed to keep you running strong. With a nutritional profile superior to other fizzy C drinks, a taste that won hands-down in blind tests and an exceptional grade of ascorbic acid, Effer-C™ is clearly the smart choice. Vitamin C Starting with a exceptional grade of Vitamin C was the first step in formulating this superior drink. Fueled by 1000 mg of highly absorbable, gentle vitamin C, you can be assured that you’re getting enough C to keep you tip-top for hours. By utilizing a buffered, non-acidic vitamin C, Effer-C™ offers fast assimilation to boost energy and restore vital electrolytes without causing gastric irritation. B-Complex Busy lifestyles rob you of so much more than just time. Physical stress and mental anxiety can drain even the healthiest individuals of energy producing, mood supporting B vitamins. As these reserves diminish, so does the ability to stay motivated, focused, patient, responsive and energetic. Effer-C™ is bursting with a full B profile that contains as much as two times the amount of certain B-vitamins found in other brands. Calcium/Magnesium Calcium and magnesium have become synonymous with strong, healthy bones. Aside from their structural supporting properties, these two minerals work synergistically to help support the body’s adenosine triphosphate (ATP) energy reserves. Individually, magnesium is present in virtually every human biological process. Many of today’s most common elements (alcohol, fluoride, processed foods) can hinder your ability to retain optimal levels of this vital nutrient. Effer-C™ brings them right back! Chromium This essential trace mineral is a primary component in the synthesis of fats, carbohydrates and proteins. Chromium also has a direct influence on the efficacy of our metabolism, in addition to how well we use glucose. Even a slight deficiency in chromium can result in fatigue, anxiety and glucose intolerance. Effer-C™ contains 20 mcg of chromium - more than even the most popular effervescent C supplement. Anti-oxidants Part of what makes Effer-C™ so effective is its unique antioxidant profile. By adding more alpha lipoic acid (ALA) than similar competing products, in addition to 5 mg of CoQ10 and zinc, Effer-C™ provides powerful protection against harmful, cell damaging free radicals. If you haven’t experienced the nutritional rush that Effer-C™ delivers, you don’t know what you’re missing. NOW makes it easier than ever to stay energized and fully replenished throughout the day, during workouts and even on the road. Available in four delicious flavors (orange, lemonlime, raspberry and cranberry Effer-C™ is a simple and effective way to maintain high levels of vitamin C and unlock the energy that’s just waiting within.

-- Buy Effer-C at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1090)

Date: December 07, 2005 01:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Immune Renew Fact Sheet

Immune Renew Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: Everyone seeking a healthy immune system; People on low carb diets or non-whole grain diets that are lacking dietary beta-glucans

KEY INGREDIENTS: Astragalus Root Extract Powder 70% polysaccharides (200 mg). Proprietary blend of 8 organically grown “medicinal mushrooms” (200 mg)

MAIN PRODUCT FEATURES: Vegetarian formula. Polysaccharides in these US-grown mushrooms grown on organic brown rice include 1,3 Beta-glucans and terpenoids. Beta-glucans may stimulate the immune system in different ways. Triterpenoids may act as mild anticoagulants. Each mushroom may have a different effect; for example, one may stimulate T-cells and another Natural Killer cells, aiding in immune defense. Mushrooms have reported beneficial effects on liver health and promoting normal cell growth.

ADDITIONAL PRODUCT INFORMATION: Some extracts from these kinds of mushrooms have been used medicinally in Japan and China. The mushrooms include Turkey Tail, Sun Mushrooms, Maitake, Cordyceps, Phellinus, Lion’s Mane, Reishi and Shiitake. The astragalus extract also contains naturally occurring astragalosides. Mushrooms may help maintain normal cholesterol and triglyceride levels

SERVING SIZE & HOW TO TAKE IT: For everyday use take one or two caps per day, either with meals or on an empty stomach.

COMPLEMENTARY PRODUCTS: Vitamin C to break down beta-glucan structures for better absorption, Inositol Hexaphosphate (IP-6), I3C, Pometrol, mixed carotenoids and antioxidants

CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. Do not take with AIDS drugs or if you have an autoimmune disease. Use with caution if using anticoagulants or blood pressure medication, as these mushrooms may have mildly synergistic effects to those drugs. Do not use if you have mold or mushroom allergies (or any sensitivities to mushrooms, cheese, etc.), which can potentially result in hives, rashes, breathing difficulties (including dry mouth or throat), stomach distress, diarrhea, or any other unusual side effect.

This information is based on my own knowledge and these references, but should not be used as diagnosis, prescription or as specific product claims.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995
2. Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 1999;19(1):65-96.
3. Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002 Nov;60(3):258-74. Epub 2002 Sep 10.
4. Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.
5. Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.
6. Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].
7. Kubo K, Nanba H. Anti-hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20:781–5.
8. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure lowering activity present in the fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988;36:1000–6.
9. Jones K. Shiitake: A major medicinal mushroom. Alt Compl Ther 1998;4:53–9 [review].
10. Taguchi I. Clinical efficacy of lentinan on patients with stomach cancer: End point results of a four-year follow-up survey. Cancer Detect Prevent Suppl 1987;1:333–49.
11. Matsuoka H, Seo Y, Wakasugi H, et al. Lentinan potentiates immunity and prolongs survival time of some patients. Anticancer Res 1997;17:2751–6.
12. Guangwen Y, Jianbin Y, Dongqin L, et al. Immunomodulatory and therapeutic effects of lentinan in treating condyloma acuminata. CJIM 1999;5:190–2.
13. Jones K. Reishi mushroom: Ancient medicine in modern times. Alt Compl Ther 1998;4:256–66 [review].
14. Kammatsuse K, Kajiware N, Hayashi K. Studies on Ganoderma lucidum: I. Efficacy against hypertension and side effects. Yakugaku Zasshi 1985;105:531–3.
15. Jin H, Zhang G, Cao X, et al. Treatment of hypertension by ling zhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Nimmi H, Xiu RJ, Sawada T, Zheng C. (eds). Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science, 1996, 131–8.
16. Suzuki H, et al. Immunopotentiating Substances in Lentinus edodes Mycelial Extract(LEM)-- Activation of Macrophage and Proliferation of Bone Marrow Cell. Nippon Shokakibyo Gakkai Zasshi. Jul1988;85(7): 1430.
17. Suzuki H, et al. Inhibition of the Infectivity and Cytopathic Effect of Human Immunodeficiency Virus by Water-soluble Lignin in an Extract of the Culture Medium of Lentinus edodes Mycelia (LEM). Biochem Biophys Res Commun. Apr1989;160(1):367-73.
18. Gordon M, et al. A Placebo-controlled Trial of the Immune Modulator, Lentinan, In HIV-positive Patients: A Phase I/II Trial. J Med. 1998;29(5-6):305-30.
19. Li JF, et al. Study on the Enhancing Effect of Polyporus Polysaccharide, Mycobacterium Polysaccharide and Lentinan on Lymphokine-activated Killer Cell Activity in vitro. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. Apr1996;16(4):224-26.
20. Li KR, et al. Anti-atherosclerotic Properties of Higher Mushrooms (a Clinico-experimental Investigation. Vopr Pitan. Jan1989;1:16-19.
21. Shouji N, et al. Anticaries Effect of a Component From Shiitake (An Edible Mushroom). Caries Res. Feb2000;34(1):94-98.
22. Levy AM. Eosinophilia and Gastrointestinal Symptoms After Ingestion of Shiitake Mushrooms. J Allergy Clin Immunol. May1998;101(5):613-20.
23. Zjawiony JK. Biologically active compounds from Aphyllophorales (polypore) fungi. J Nat Prod. 2004 Feb;67(2):300-10.
24. Oliva D. Cellular and physiological effects of Ganoderma lucidum (Reishi). Mini Rev Med Chem. 2004 Oct;4(8):873-9.
25. Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem. 2000 Jul;7(7):715-29.
26. Borchers AT, Stern JS, Hackman RM, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med. 1999 Sep;221(4):281-93.
27. Mau JL, Lin HC, Chen CC. Antioxidant properties of several medicinal mushrooms. J Agric Food Chem. 2002 Oct 9;50(21):6072-7.
28. Hirasawa M, Shouji N, Neta T, Fukushima K, Takada K. Three kinds of antibacterial substances from Lentinus edodes (Berk.) Sing. (Shiitake, an edible mushroom). Int J Antimicrob Agents. 1999 Feb;11(2):151-7.
29. Rajewska J, Balasinska B. Biologically active compounds of edible mushrooms and their beneficial impact on health. Postepy Hig Med Dosw (Online). 2004 Oct 5;58:352-7.
30. Chang R. Functional properties of edible mushrooms. Nutr Rev. 1996 Nov;54(11 Pt 2):S91-3.
31. Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov;25(11):1387-95. PMID: 15525457
32. Cheung NK, Modak S, Vickers A, Knuckles B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol Immunother. 2002 Nov;51(10):557-64. Epub 2002 Sep 20. PMID: 12384807
33. Shamtsyan M, Konusova V, Maksimova Y, Goloshchev A, Panchenko A, Simbirtsev A, Petrishchev N, Denisova N. Immunomodulating and anti-tumor action of extracts of several mushrooms. J Biotechnol. 2004 Sep 30;113(1-3):77-83. PMID: 15380649
34. Zhang YD, Shen JP, Zhu SH, Huang DK, Ding Y, Zhang XL. Effects of astragalus (ASI, SK) on experimental liver injury Yao Xue Xue Bao. 1992;27(6):401-6. Chinese. PMID: 1442065
35. Sheng BW, Chen XF, Zhao J, He DL, Nan XY. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Chin Med J (Engl). 2005 Jan;118(1):43-9. PMID: 15642225
36. Yesilada E, Bedir E, Calis I, Takaishi Y, Ohmoto Y. Effects of triterpene saponins from Astragalus species on in vitro cytokine release. J Ethnopharmacol. 2005 Jan 4;96(1-2):71-7. PMID: 15588652
37. Li C, Cao L, Zeng Q. Astragalus prevents diabetic rats from developing cardiomyopathy by downregulating angiotensin II type2 receptors' expression. J Huazhong Univ Sci Technolog Med Sci. 2004;24(4):379-84. PMID: 15587404
38. Wang SH, Wang WJ, Wang XF, Chen W. [Effect of Astragalus polysaccharides and berberine on carbohydrate metabolism and cell differentiation in 3T3-L1 adipocytes]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Oct;24(10):926-8. Chinese. PMID: 15553830
39. Shao BM, Dai H, Xu W, Lin ZB, Gao XM. Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun. 2004 Oct 8;323(1):133-41. PMID: 15351712
40. Mao SP, Cheng KL, Zhou YF. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Feb;24(2):121-3. Chinese. PMID: 15015443
41. Guo FC, Williams BA, Kwakkel RP, Li HS, Li XP, Luo JY, Li WK, Verstegen MW. Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poult Sci. 2004 Feb;83(2):175-82.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=983)

Date: November 23, 2005 06:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PeakImmune4

New from:

Daiwa Health Developement

PeakImmune4™

Clinically Shown to Triple Natural Killer (NK) Cell Activity

• A dietary supplement containing the same immune complex previously sold to a veryloyal customer base.

• May help safely and naturally to modulate your immune system to perform its roleagainst foreign invaders.

• Based on a patented and proprietary Rice Bran Arabinoxylan Compound, clinicallyshown to triple the activity of Natural Killer cells—white blood cells that are consid-ered the body’s first line of defense.

• Also doubles immune system T cell count, increases B cell count, and boosts chemi-cal messengers critical to intercellular communication for fighting pathogens.

• An immune modulator, which does not result in hyporesponsiveness or hyperrespon-siveness of the immune system; it therefore does not lose effectiveness over time, norcause the immune system to attack itself.

• No need to cycle on or off of PeakImmune4 as with some other immune products.

• Efficacy and safety shown in clinical studies and in practice by tens of thousands ofusers worldwide.

  4 capsules contain:

  Proprietary RBAC* Blend1000 mg
  Rice BranHyphomycetes Mycelia Extract (from Shiitake Mushroom)

  *RBAC (Rice Bran Arabinoxylan Compound)

  Suggested use: As a dietary supplement, take four (4) capsules before or after a meal. Forthe best results, the following two-step program is recommended:

  1st step:Take 4 capsules 3 times per day for 4 weeks.

  2nd step:After 4 weeks, reduce dosage to the maintenance level of 4 capsules daily.

  PeakImmune4 is a trademark of Daiwa Health Development, Inc.

  
  
  --
  Peakimmune4 available at Vitanet
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=962)

  ---

  Preventing Chronic Health Problems with AHCC
  

  Date: October 26, 2005 05:57 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Preventing Chronic Health Problems with AHCC
  

  Preventing Chronic Health Problems with AHCC

  In a country supposedly as healthy as ours, an estimated 175 million people suffer from one form of chronic imbalance or another. This can take the form of obesity, which is the second leading cause of preventable death in the United States, second only to cigarette smoking; challenges to heart health, blood pressure, blood glucose levels, joint and cell health ,to name just a few.

  In fact ,treating chronic health problems is what modern medicine has become .Sure, there are still many acute illnesses treated by modern medicine; but for the most part, we are fortunate enough to have long life spans and the health issues that go along with it. Therefore it is important to make sure that out immune systems are up to the task. That is where AHCC should become part of our daily lives.

  AHCC is an nutritional supplement that was developed and is manufactured solely in Japan under strict practices. It is a hybridized extract of medicinal mushrooms where the active ingredient is an oligosaccharide made from the mycelia of several species of mushrooms, grown in rice bran.

  AHCC and Cell Senescence

  Every few years, a new buzz word comes along in medical circles. The latest one to be used both in a positive and negative fashion is senescence. For example, if an unhealthy cell can be artificially made to senesce, or grow old, then it will die sooner. If senescence of healthy cells can be delayed, that is an amazing achievement.

  AHCC is the first nutritional supplement that shows principles of being able to promote certain cells in the immune system that keep us young and healthy, thus delaying immunosenesnscence.

  AHCC and the Immune System

  In order to get a full appreciation of how important taking AHCC on a daily bases is, one needs to understand the intimate role the immune system plays in our daily lives. It is responsible for riding our bodies of the unhealthy cells that are produced every day. The immune system protects us from the polluted air we breathe, the chemicaalized foods we eat, and most importantly, from the stress we bring upon ourselves just by the very nature of the way we live our lives. Our bodies were made for flight or fight capability; but never in history have we been in that mode on a daily basis. Our immune systems are under constant assault and it is up to you to take care of it even though you may not even be aware that it is there. We tend to only to think of our immune system when it is not working-when suffer mild or severe health challenges.

  Without getting into too much detail, our immune system is a complex series of cells that all communicate with each other and must be balanced correctly in order for us to stay healthy. AHCC is able to encourage the helpful cells such as the natural killer (NK) cells while suppressing the ones that foster problems.

  I am in clinical practice on a daily basis and use AHCC in almost every one of my patients. It is very versatile because of its effects on the immune system.

  A Company Committed to Excellence

  If everything I just told you wasn’t enough to convince you that AHCC should become part of your daily armamentarium, then here’s more fuel. AHCC is produced by a chemical company that is committed to excellence in manufacturing and most importantly in research. They have supported research at hospitals around the world, including local ones such as Columbia University, Harvard University and the University of California.

  In fact, I just returned from a trip to Sapporo, Japan where the product is made and where each year, a team of scientists and medical professionals gather to discuss the latest research on AHCC, GCP, and oliganol-all products made by the same company. This was the 13th annual symposium and was attended by close to 1000 professionals.

  It is remarkable to me that this company is able to produce such well-documented research while still being a nutritional supplement company, which shows it can be done. To me, this is the sign of a nutritional supplement worth recommending. If it does what it says it is supposed to do and has research to support those claims, than that is something you want in your daily diet.

  So, even though you may never have given your immune system a second thought, you really should; and the best way to help it out is by taking AHCC on a daily basis, just like I do. I recommend 500 mg per day in the summer months and 1500 per day in the winter months as a simple preventive. Stay healthy!

  About the Author

  Fred Pescator, M.D., a traditionally trained physician practicing nutritional medicine, is President of the AHCC Research Association. He is the author of The Hamptons’ Diet, Thin For Good and Feed Your Kids Well. Dr.Pescator lectures around the world, and has been featured on such shows as The View, The Today Show, Deborah Norville, The O’ Reilly Factor, and Extra. Recent interviews include Woman’s Health and Fitness, Let’s Live, the New York Times, the Wall Street Journal, Fortune and more. He is also the author of numerous papers and magazine articals. Dr.Pescator is actively involved in clinical research , and is instrumental in developing and clinically testing many of the leading nutritional products. He is the President-Elect of the International and American Association of Clinical Nutritionists and a member of the National Association of Physician Broadcasters.

  The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

  AHCC 49% OFF

  
  

  
  
  --
  Buy AHCC at 49% OFF here at Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=902)

  ---

  Benefits of Total Daily Formula
  

  Date: October 13, 2005 04:45 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Benefits of Total Daily Formula
  

  Benefits of Total Daily Formula

  Mixed Carotenoids

  All fruits and vegetables contain carotenes, the plant pigments responsible for the rich variety of colors we enjoy in the natural world. Beta carotene is the most familiar member of the carotene family. But beta carotene never exists by itself; it is always found with other carotenes in foods. We need more than just beta carotene alone. Carotenes are powerful antioxidants, which means they help reduce the body's free radical burden. Research suggests that carotenes work as a team to keep us healthy.5 Total Daily Formula provides beta carotene, alpha carotene, lutein, lycopene, zeaxanthin and cryptoxanthin from natural sources such as algal extracts, carrot oil, marigold and tomatoes (Caromix®).

  Corn-Free Vitamin C

  Total Daily Formula uses only corn-free vitamin C (ascorbic acid). The full daily intake of 6 tablets provides an exceptionally generous 800 mg of vitamin C.

  Optimum B Vitamin Servings

  Total Daily Formula supplies ample amounts of all essential B vitamins. Vitamin B3 is given as niacin plus an extra helping of niacinamide, the non-flush form of this important vitamin. The body uses pantothenic acid (vitamin B5) to deal with stress, so the formula provides 150 mg, which is 15 times the RDA. Vitamin B6 is another B vitamin people may run short of, so 60 mg -- 30 times the RDA -- is supplied. The formula contains 800 mcg of folic acid, the vitamin now recognized by the FDA as essential for prevention of neural tube defects in unborn babies. Folic acid also helps prevent accumulation in the body of homocysteine, a metabolite of the amino acid methionine.6 A high blood homocysteine level is now considered to be a risk factor for heart disease.7

  Flavonoids

  Flavonoids, also known as "bioflavonoids." are plant pigments widely distributed throughout the plant kingdom.8 Previously known as "Vitamin P," because they help reduce capillary permeability (leakiness) flavonoids are now regarded as "semi-essential" non-vitamin nutrients that benefit health in a variety of ways.9 In addition to maintaining the structure of blood vessels, flavonoids function as versatile antioxidants. Flavonoids protect vitamin C from destruction by free-radicals, helping to preserve the body's vitamin C supply.10 Total Daily Formula provides 100 mg of pure flavonoids from 112 mg of citrus extract.

  Three superior sources of Calcium

  Total Daily Formula contains three of the best absorbed and most effective forms of calcium available. MCHC (microcrystalline hydroxyapatite concentrate) is a naturally-derived compound composed of calcium, plus all the minerals and organic factors in living bone tissue. MCHC has been clinically shown to benefit bone health.11 Calcium citrate malate is a very well-absorbed form of supplemental calcium shown in recent research to be helpful for postmenopausal women.12,13 Calcium glycinate is chelated with the amino acid glycine, one of the most efficient mineral carriers for effective absorption.14,15

  Magnesium glycinate

  Magnesium is essential for strong bones and healthy hearts. This versatile mineral also regulates nerve function, keeps muscles relaxed and coordinates activity of over 300 enzymes in the body.16 Total Daily Formula contains 100 percent magnesium glycinate for exceptional absorption and gentleness on the intestinal tract.17 Magnesium glycinate has been clinically tested on people with severe malabsorption with excellent results.18

  Trace Minerals

  Total Daily Formula provides - in addition to zinc, chromium, selenium and iodine - vanadium and molybdenum. Vanadium helps maintain normal blood sugar.19 Molybdenum works as a co-factor for enzymes that help detoxify and eliminate foreign substances from the body.20

  Bioperine® for Enhanced Absorption

  Bioperine® is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine®. 21 Betaine HCL - supplies HCL (hydrochloric acid) to assist digestion. All natural tablet coating made of vegetable concentrate and beta carotene.

  Scientific References
  1. Cheraskin, E. Ringsdorf, W.M., Clark, J.W. 1968. Diet and Disease. (p. 16). New Canaan, CT: Keats Publishing.

  2. Morgan, K.J. et. al. Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition. 1985;4:195-206.

  3. Lakschmanan, F.L., Rao, R.B., Kim, W.W., Kelsay, J.L. Magnesium intakes, balances and blood levels of adults consuming self-selected diets. American Journal of Clinical Nutrition 1984;40:1380-89.

  4. Mertz, W. The Essential Trace Elements. Fed. Proc. 1970;29:1482.

  5. Perry, G. Byers, T. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Annu. Rev. Nutr. 1992;12:139-59.

  6. Landgren, F., et. al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Int Med 1995;237:381-88.

  7. Clarke, R., et. al. Hyperhomocysteinemia: an independent risk factor for vascular disease. New Eng J Med 1991;324:1149-55. 8. Havsteen, B. Flavonoids, a class of natural compounds of high pharmacological potency. Biochemical Pharmacology 32(7):1141-48.

  9. Middleton, E. The flavonoids. TIPS 1984; 5:335-38.

  10. Roger, C.R. The nutritional incidence of flavonoids: some physiological and metabolic considerations. Experientia 44(9):725-804.

  11. Dixon, A. St. J. Non-hormonal treatment of osteoporosis. British Medical Journal 1983;286(6370):999-1000.

  12. Smith, K.T. et. al. Calcium Absorption from a new calcium delivery system (CCM). Calcif Tissue Int 1987;41:351-352.

  13. Dawson-Hughes, B. et. al. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. New England Journal of Medicine 1990 Sep 27;323(13):878-883.

  14. Albion Research Notes Vol. 4, No. 1, ©Albion Laboratories Jan,1995.

  15. Ashmead, H.D. Intestinal Absorption of Metal Ions and Chelate, Springfield: Charles C Thomas, ©1985.

  16. Wester, P.O., Dyckner, T. The importance of the magnesium ion. Magnesium deficiency-symptomatology and occurrence. Acta Med Scand 1992; (Suppl) 661:3-4.

  17. Albion Research Notes Vol. 3, No. 1, ©Albion Laboratories, Feb 1994.

  18. Schutte, S., et. al. Bioavailability of Mg diglycinate vs MgO in patients with ileal resections. Abstract 115, AJCN 1992;56(4).

  19. Cohen, N. et. al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin Invest 1995; 95:2501-09.

  20. Sardesi, V.M. Molybdenum: An essential trace mineral element. Nutr Clin Pract 1993; 8:277-81.

  21. Bioperine® - Nature's Bioavailability Enhancing Thermo-nutrient. Executive Summary' 1996; Sabinsa Corporation, Piscataway, N.J.

  
  
  --
  Discount Vitamins at Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=839)

  ---

  Cinnamon Bark - Live Life to the Fullest
  

  Date: September 10, 2005 01:46 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Cinnamon Bark - Live Life to the Fullest
  

  The Spice of Life

  Once traded for gold, cinnamon has also been used traditionally for its benificial properties and is currently being studied for its reputed role in blood glucose support. In addition, this precious spice offers antioxidant protection from harmful free radicals.

  One of the world's most popular and teasured spices, Cinnamon Bark has a long history of use not only for culinary purposes, but also for dyspeptic complaints such as mild spasms of the gastrointestinal tract, bloating, flatulence, and as a digestive and respitory aid.

  Cinnamon may well be worth its weight in gold.

  Live Life to the Fullest

  2 Capsules contain 1000mg Cinnamon Bark - Vegetarian - Easy to swallow

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=776)

  ---

  MSM - Natures Primary Sources of Organic Dietary Sulfur
  

  Date: August 02, 2005 03:48 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: MSM - Natures Primary Sources of Organic Dietary Sulfur
  

  
  

  Best MSM The MSM Story-One of Nature's Primary Sources of Organic Dietary Sulfur! The human body requires a continuous supply of usable sulfur, and MSM is one of the primary organic sulfur-containing molecules for use by living organisms. From life's earliest beginnings, primitive marine organisms (blue-green algae and phytoplankton) have absorbed inorganic sulfur from ocean waters and produced organic sulfur molecules, primarily dimethyl sulfonium salts. These salts are released back into the sea, where they are converted to dimethyl sulfide, which readily evaporates, ending up in the upper atmosphere. Dimethyl sulfide is then oxidized by UV light, forming DMSO and MSM. The two compounds are delivered to land masses in rain water, and absorbed by plants. MSM is a stable end-product of this process, and thus serves as a primary source of sulfur in the food chain. Though present on earth since before life appeared on dry land, and known to science since the 1950's, MSM has only recently been recognized as having importance in human nutrition. Why the Human Body Needs MSM MSM occurs naturally in the blood, body fluids and tissues. It is now believed that a minimum MSM concentration of 0.2 parts per million is necessary for the body to function normally. MSM may be the most easily absorbed and non-toxic source of nutritional sulfur occurring in nature. Sulfur is a structural mineral that maintains the strength of various tissues by forming sulfur "tie-bars" (sulfhydryl bonds) between connective tissue proteins. MSM serves as a readily available source of sulfur for this function, and thus helps maintain the pliancy of tissues and cell membranes. Repair of damaged tissue depends upon a supply of sulfur for continuation of reactions involving sulfhydryl groups (-SH). Sulfur is required for the maintenance of healthy hair, skin and nails. In view of the presence of MSM in biological systems since the beginning of evolution, it is logical to assume that all higher life forms, including humans and animals, are well adapted to use MSM as a sulfur donor. MSM Benefits Clinical research on the role of MSM in the human body has culminated in the filing of several patents covering numerous uses for MSM as a dietary ingredient for both humans and animals. As a result of these investigations, it is believed that physical and psychological stress increases in the human body when the MSM concentration falls below minimum levels, resulting in a loss of normal organ function. Based on observations, ingestion of MSM by humans has the following beneficial effects: • MSM supports maintenance of strong, healthy body tissues by donating sulfur for formation of sulfur tie-bars between connective tissue proteins.* • MSM supports normal gastrointestinal function.* • MSM improves the body's resistance to adverse physical stress.* • MSM supports mental alertness and maintenance of healthy mood.* • MSM promotes the body's processes that heal tissue.* • MSM helps modify the physiologic response to allergens.* • MSM supports normal lung function.* • MSM supports normal relaxation of muscles.* • MSM supports normal joint function.* • MSM helps maintain healthy skin.* Supplementation is Needed to Realize the Benefits of MSM Widespread in nature, MSM is found in a variety of foods, including fresh fruits and vegetables, raw milk, raw meat and raw fish. However, MSM is a volatile substance easily lost during cooking, pasteurization, food processing and storage. The average American diet thus supplies at best a marginal MSM intake, which may be inadequate to maintain the optimum MSM concentration in the body. The body's MSM concentration is also believed to decline with increasing age. Dosage Recommendations Effective dosages for the various reported uses of MSM range from 500 mg to 6 grams per day. 1000 mg per day is recommended to restore normal MSM concentrations, while higher doses may be necessary for specific uses. MSM is considered to be as non-toxic to the body as water, and is therefore completely safe at the higher dosage levels. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Scientific Abstracts and References 1. Jacob, S., Herschler, R. Introductory remarks: dimethyl sulfoxide after 20 years. Annals of the New York Academy of Sciences 1983; 411:xiii-xvii. 2. Herschler, R. Dietary and pharmaceutical uses of methylsulfonylmethane and compositions comprising it. United States Patent 4,514,421; April 30, 1985. 3. Herschler, R. Methylsulfonylmethane in dietary products. United States Patent 4,616,039; October 7, 1986. 4. Sellnow, L. MSM: An Aid From Nature. The Blood Horse, June 6, 1987:3459-3462. 5. Lawrence, R.M. Methyl-sulfonylmethane (M.S.M.) A double-blind study of its use in degenerative arthritis. International Journal of Anti-Aging Medicine 1998;1(1):50 6. Jacob, S.W., Lawrence, R.M., Zucker, M. 1999. The Miracle of MSM. New York: G.P. Putnam's Sons. -- Vitanet ®

  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=720)

  ---

  Digest Active - For Occasional Indigestion
  

  Date: June 29, 2005 02:39 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Digest Active - For Occasional Indigestion
  

  It feels great when you’ve eaten well and your body has been energized with nutrients. But with your busy schedule, you might not always be able to eat well, and your body might not have the time or energy to properly digest your meals. The result: occasional indigestion and low energy because your food doesn’t get broken down enough to release the energizing nutrients you need. And poor digestion can lead to long-term health imbalances. To reclaim the energy from your nutrients, Source Naturals, the science company, introduces DIGESTACTIV, a Bio-Aligned Formula™ designed to work with your body to stimulate optimal digestion. DIGESTACTIV contains the high potency, broad-spectrum blend of digestive enzymes found in our best-selling ESSENTIAL ENZYMES™, plus digestion-stimulating ingredients such as bromelain, papain and ginger. When you want digestive stimulation along with the nutrient releasing power of ESSENTIAL ENZYMES for occasional indigestion, take DIGESTACTIVE.

  Bio-Aligned™ Digestive Support

  DIGESTACTIV™ is scientifically formulated to support the body systems involved in healthy digestion. There are herbs and other ingredients to promote the digestive stimulant system and enzymes to promote the digestive systems for releasing nutrients from food. These ingredients work together to optimize the amount of energizing nutrients you can assimilate from your meals and to relieve occasional indigestion, occasional constipation, sour stomach, bloating and gas.

  Digestive Stimulant System

  DIGESTACTIV contains many ingredients that help stimulate your digestive process to promote healthy nutrient accessibility. Betaine HCl (hydrochloric acid) supports the acidic environment needed in your stomach to digest food. The bitter herbs gentian, ginger, peppermint and quassia all stimulate the appetite and the gastric juices needed for digestion. Bioperine® is a pepper extract that increases thermogenic, or heat generating reactions in the gastro-intestinal tract, which facilitates enhanced bioavailability of nutrients.

  Nutrient Digestion Systems

  DIGESTACTIV also contains enzymes that work throughout the varying sections and pH (or acidity) levels of your digestive system. For the carbohydrate digestive system, there are amylase, amyloglucosidase and lactase. Amylase and amyloglucosidase convert starch into smaller, simpler sugars. Lactase breaks down the milk sugar lactose, which many adults are unable to digest. For the protein digestive system, there are acid stable protease and vegetarian pancreatin to promote protein digestion in a wide range of pH levels. Additional protein digestion support comes from the pineapple enzyme bromelain, the papaya enzyme papain, and betaine HCl, which promotes the acidity level needed to denature proteins for digestion of their building blocks, amino acids. For the fat digestive system, there is lipase to promote the healthy breakdown of fats, or triglycerides, into their nutrient building blocks, fatty acids and glycerol.

  For the fiber digestive system, there are cellulase and hemicellulase to break down the sturdy cell walls in fibrous plants, thereby releasing more nutrients for digestion.

  Popular Efficacy

  DIGESTACTIV contains all the key ingredients found in the best-selling ESSENTIAL ENZYMES™. ESSENTIAL ENZYMES is a popular product because it addresses body systems in addition to symptoms* of digestive imbalance. And it works. Increasing the breakdown of nutrients in the digestive system results in fewer digestive symptoms* as well as better nutrient availability. And DIGESTACTIV has added enzymes and herbs to promote digestive stimulation for relief of occasional indigestion. Source Naturals is pleased to partner with your local health food store to bring you the unique health benefits of DIGESTACTIV. There is a revolution underway in how we think about and maintain our health, and natural food stores and outlets are at the forefront. You can benefit right now—long before word spreads to the general public—with the innovative nutrition of Source Naturals DIGESTACTIVE.

  Health Strategies for Digestive Wellness

• • Eat slowly to give your body time to generate digestive juices as well as savor your food.
• • Eat a balanced, whole foods diet to maximize your access to energizing bioavailable nutrients.
• • Drink plenty of water to supply much needed fluid for digestion.
• • Try to relax when eating, to promote the flow of your digestive juices.
• • Stay active, because regular exercise helps to promote healthy digestion.
• • Eat plenty of fiber to provide your GI tract with the bulk needed for healthy digestion.
• • Eat probiotics, beneficial bacteria that help you digest foods These include acidophilus, which is found in yogurt, and bifidus.
• • Eat prebiotic carbohydrates found in fruits and vegetables, such as FOS (fructooligosaccharides), to feed the friendly bacteria that live in your intestines and help your digestion.
• • Supplement your diet with digestion promoting products such as Source Naturals probiotics ACIDOPHILUS, LIFE FLORA™, SUPER CARROT ACIDOPHILUS™, and BIFIDYN™, prebiotic NUTRAFLORA® FOS, and fibers such as CHOLESFIBER™, GRAPEFRUIT PECTIN, GUAR GUM, OAT BRAN 1000™, and PSYLLIUM HUSK POWDER.

  DigestActiv™ is a Bio-Aligned Formula™ Multi-System Support for Occasional Indigestion

  Carbohydrate Digestive System: Amylase, Amyloglucosidase, Lactase

  Protein Digestive System: Vegetal Analog of Pancreatin, Acid Stable Protease, Bromelain, Papain, Betaine HCl

  Fat Digestive System: Lipase

  Digestive Stimulant System: Betaine HCl, Bioperine®, Gentian Root, Ginger, Peppermint, Quassia

  References
  Bland. J. (1993). Digestive Enzymes. Keats Publishing Co. Holcenberg, J. et al. (1981). Enzymes as Drugs. John Wiley and Sons: New York. 331-340. Linder, M. (1991). Nutritional Biochemistry and Metabolism. Appleton & Lange. * The term symptom as used above refers to the effects of nutrient shortages or imbalances and is not related to the diagnosis, treatment, cure, or prevention of any disease.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=533)

  ---

  GREEN COFFEE EXTRACT - Powerful Natural Antioxidant
  

  Date: June 29, 2005 11:06 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: GREEN COFFEE EXTRACT - Powerful Natural Antioxidant
  

  Green Coffee Extract

  According to the National Coffee Association’s 2001 National Coffee Drinking Trends survey, 52 percent, or 107 million, U.S. adults drink coffee each day. Although you may already enjoy coffee as your favorite way to begin the morning, new studies are revealing its impressive health benefits. GREEN COFFEE EXTRACT (GCA®) is a newly discovered powerful antioxidant that helps protect against oxidative stress caused by free radicals - a major cause of accelerated aging. Source Naturals GREEN COFFEE EXTRACT (GCA®) is a patent-pending, all-natural green coffee bean extract derived from raw, unroasted coffee beans. It is high in chlorogenic and caffeic acids, two primary compounds responsible for its antioxidant activity. GREEN COFFEE EXTRACT is naturally low in caffeine and contains at least 65 percent total polyphenol antioxidants.

  The Coffee Story

  The history of coffee dates back more than a thousand years. Originally, coffee beans were used as food. East African tribes would grind the coffee berries together, mixing the results into a paste with animal fat. Later, around 1000 AD, Ethiopians made a type of wine from coffee berries, fermenting the dried beans in water. Coffee also grew naturally on the Arabian Peninsula where it was first developed into a hot drink. Despite decades of research on coffee and caffeine, there are many misconceptions about the potential health risks associated with coffee, while many of the beneficial aspects have gone unnoticed.

  Polyphenols: Powerful Antioxidants

  Phenolic compounds, or polyphenols, are a widespread family of compounds found in all plants including grapes, coffee and tea. They possess outstanding antioxidant and free radical scavenging properties, which may help defend cells and protect the body against the effects of aging. The high antioxidant activity observed in research on coffee is believed to be mostly due to the phenolic acids. GREEN COFFEE EXTRACT contains a number of polyphenols called hydroxycinnamic acids, with the two most prominent being chlorogenic and caffeic acids. Caffeic acid is the most abundant phenolic compound in coffee. In vitro and in vivo studies show that these acids protect against low-density lipoprotein (LDL) oxidation and lipid peroxidation.

  Glucose Metabolism

  There is accumulating evidence that certain dietary polyphenols, such as chlorogenic acid, may have biological effects in the small intestine that alter patterns of glucose uptake. Chlorogenic acid has been shown to inhibit glucose 6 phosphate (Glc-6-Pase) activity. Glc-6-Pase is an enzyme that has a key role in regulating glucose metabolism. An in vivo study on rats demonstrated that chlorogenic acid improved glucose tolerance.

  Natural Wellness

  Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN COFFEE EXTRACT.

  References:
  Nardini, M. et al. 2002. Absorption of phenolic acids in humans after coffee consumption. J Agric Food Chem (50):5735-5741. Arion, W.J. et al. 1997. Chlorogenic acid and hydroxynitrobenzaldehyde: new inhibitors of hepatic glucose 6-phosphatase. Archives of Biochemistry and Biophysics. 339 (2):315-322. Rodriquez de Sotillo, Delcy V. & Hadley, M. 2002. Chlorogenic acid modifies plasma and liver concentrations of: cholesterol, tracylglycerol, and minerals in (fa/fa) Zucker rats. J. Nutr Biochem 13:717-726.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=525)

  ---

  HISTORY
  

  Date: June 25, 2005 10:57 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: HISTORY
  

  HISTORY

  Ginkgo has achieved unprecedented popularity within the last decade and has become a familiar household term. Because interest in treating diseases like Alzheimer’s has escalated over the last decade, the biochemical capabilities of ginkgo in regard to brain function have been investigated and are still being researched. Ginkgo is one of those herbs that has become intrinsically connected with notions of herbal elixirs capable of pre s e rving youth and promoting longevity.

  Ginkgo comes from the oldest species of tree in the world dating back some 200 million years. Some ginkgo trees have been known to live well over an average of 1000 or more years. The ginkgo tree is also known as the “maidenhair tree” and would have probably become extinct if the trees had not been cultivated in Far Eastern temple gardens and nurtured by Oriental monks.

  Ginkgo is a deciduous conifer with separate male and female types. It resembles the pau d’arco tree and like pau d’arco, possesses an unusual immunity to insects and diseases. Ginkgo’s remarkable hardiness enabled it to survive the atomic blast at Hiroshima. Because of its unprecedented longevity, ginkgo biloba has sometimes been referred to as a living fossil.

  Ginkgo has been used in China for over 5000 years. The Chinese refer to the fruit of the ginkgo tree as pa-kwo. This fruit is sold in markets throughout China and resembles dried almonds. Ginkgo fruit is pleasant tasting when fresh, but can become quite disagreeable if allowed to get overly ripe. Asians have relied on extracts of the fan-shaped ginkgo leaf since 3,000 B.C. to heal a wide variety of ailments.

  The Chinese have been acquainted with the curative powers of ginkgo for centuries and have typically used the herb for ailments related to aging, such as circulatory disorders, mental confusion and memory loss. In China, ginkgo seeds, called baigou, are considered lung and kidney tonics and are used in conjunction with acupuncture. Ginkgo seeds also help to tonify the urinary system, so they are used in cases of incontinence and excessive urination.1

  Practitioners of Chinese medicine routinely use ginkgo leaves. Ginkgo was introduced into Eu rope in 1730 and was we l l received, not for its medicinal value, but for its ornamental appeal. It is used extensively in landscaping because of its lovely fern-like leaf. It was brought to America in 1784 to the garden of William Hamilton who lived in Pennsylvania.

  Decades passed before the healing properties of ginkgo we re investigated. Consequently, it has been part of the herbal repertoire only since the 1980s. During this time, it became technically feasible to isolate the essential components of ginkgo. Pharmacologically, there are two groups of substances which are significant compounds found in ginkgo: the flavonoids, which give ginkgo its antioxidant action, and the terpenes, which help to inhibit the formation of blood clots. The majority of scientific interest has focused on Ginkgo’s ability to improve the circulation of blood. O ver the past twenty years, scientific testing on the plant has dramatically escalated. Ha rva rd professor Elias J. Core y, Ph . D , synthesized ginkgo’s active ingredient, ginkgolide B, for the first time in the laboratory. Consequently, stepped-up research in this country and in Eu rope resulted. Ginkgo has been the subject of over 300 scientific studies and continues to intrigue scientists. Much modern research has confirmed ancient applications of ginkgo as well as discovered new ones.

  Ginkgolide, the active component of the herb, is what creates most of ginkgo’s biochemical attributes. Exactly how ginkgolide B functions is not yet known. One theory is that the compound somehow interferes with a chemical found in the body called PAF (platelet activating factor). PAF has been implicated in cases of graft rejection, asthma and other immune disorders. PAF antagonists have been identified from a variety of medicinal plants. These compounds help to explain the pharmacological basis of several traditional medicines and provide a valuable new class of therapeutic agents.

  Particular attention has been paid to ginkgo’s powerful actions on the cardiovascular system. Thousands of Europeans use this herb for peripheral circulatory disorders. As a circulation booster, ginkgo has accumulated some impressive credentials. Because proper circulation is vital to each and every body function, virtually all body systems can benefit from ginkgo therapy.

  Ginkgo’s relationship to brain function has also spawned considerable interest. In 1985, Rudolf Weiss said of ginkgo,

  “ Significant improvement in mental states, emotional lability, memory, and the tendency to tire easily, have been reported.”

  Ginkgo is currently planted in groves and used for a number of medicinal purposes. It is harvested in the summer and can be used in extract, tincture or infusion forms. The therapeutic properties of ginkgo seem endless. Continuing re s e a rch promises to further uncover additional health benefits of this remarkable botanical. Ginkgo extracts are among the leading prescription medications in France and Germany. Currently, millions of prescriptions for ginkgo are written by physicians worldwide.

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=447)

  ---

  America's Most Wanted
  

  Date: June 14, 2005 05:23 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: America's Most Wanted
  

  America's Most Wanted

  by Brian Amherst Energy Times, January 6, 2000

  The United States eats well, a little too well, according to experts. Amply supplied with a large supply of high-calorie food, our diets might seem to be chock full of every conceivable nutrient. Well, to the question "Getting all the right vitamins, minerals and other nutrients?" the most appropriate answer seems to be "Not exactly." Eating a lot doesn't equal eating a lot of the most important vitamins and minerals. So, which vitamins and minerals are likely to show up in short supply in the typical American diet? Calcium certainly sits at the top of list. According to the most recent Continuing Survey of Food Intake by Individuals, which is conducted by the United States Department of Agriculture (USDA), women and girls age 12 and up are not consuming adequate calcium from their diet. Research reveals that about 1200 mg. day suffices for those over age 50 and 1000 mg a day should be adequate if you're between the ages of 19 and 50. Since strong bones are formed during "the first three decades of life," says Laura Bachrach, MD, of Since strong bones are formed during "the first three decades of life," says Laura Bachrach, MD, of Stanford University, ". . .osteoporosis is a pediatric disease." For long-range protection against that bone-weakening disease, kids should eat calcium-rich, low-fat dairy products and plenty of leafy greens (broccoli, cabbage, kale) as well as salmon (with bones), seafood and soy. But the calcium campaign does not end in early adulthood. Bone mass begins to deteriorate at about age 30. Menopausal hormonal changes can exacerbate bone brittleness. Medical conditions, including cancer, liver disease and intestinal disorders; prescription drugs; tobacco and alcohol indulgence; or a decline in activity, especially the weight-bearing kind, also jeopardize bone strength. According to the National Osteoporosis Foundation, about one in every two American women will break a bone after age 50 due to osteoporosis. That translates into about half a million fractured vertebrae and more than 300,000 shattered hips. Frequently, those breaks are life-threatening.

  Crucial Calcium

  The critical role of calcium in many body functions is perhaps the most extensively clinically documented among nutrients. Researchers in the Department of Medicine, Oregon Health Sciences University in Portland, reviewed epidemiological and clinical studies conducted over the past two years on the relationship between dietary calcium and blood pressure (J Am Coll Nutr October 1999: 398S-405S). "Nearly 20 years of investigation in this area has culminated in remarkable and compelling agreement in the data," the researchers report, "confirming the need for and benefit of regular consumption of the recommended daily levels of dietary calcium." Investigators at the State University of New York, Buffalo School of Dental Medicine, presented results of their studies of calcium and vitamin C and gum disease at the June 26, 1998 meeting of the International Association for Dental Research. Two separate inquiries revealed that people who consumed too little calcium as young adults, and those with low levels of vitamin C in their diets, appear to have nearly twice the risk of developing periodontal disease later in life than folks with higher dietary levels of either nutrient.

  Calcium: Much Documented Researchers offer extensive evidence of calcium's benefits on many fronts: n Osteoporosis poses a threat to older men as well as women, according to Randi L. Wolf, PhD, research associate at the University of Pittsburgh Graduate School of Public Health. Dr. Wolf presented her award-winning study to an October 3, 1999 meeting of the American Society for Bone and Mineral Research. Dr. Wolf suggests that men increase their consumption of calcium, particularly after age 80, to avoid age-related declines in the amount of calcium absorbed. According to Dr. Wolf, "It appears that the hormonal form of vitamin D, which is the main regulator of intestinal calcium absorption, may have an important role. We are conducting more research to better understand the reasons for why calcium absorption declines with age in men." n Scientists at Tufts University in Boston did some earlier work on the calcium-vitamin D connection and reported it in the September 4, 1997 New England Journal of Medicine. Using the National Academy of Sciences (NAS) increased recommended daily intake of 1200 milligrams of calcium and 400 to 600 international units of vitamin D for people over 50, the Tufts researchers found that with supplementation of the nutrients, men and women 65 and older lost significantly less body bone and, in some cases, gained bone mineral density. n Two studies published in American Heart Association journals show that atherosclerosis and osteoporosis may be linked by a common problem in the way the body uses calcium. The September 1997 Stroke revealed that, in a group of 30 postmenopausal women 67 to 85 years old, bone mineral density declined as atherosclerotic plaque increased. Researchers reporting in Circulation (September 15, 1997) advanced the theory that the osteoporosis-atherosclerosis connection may be related to a problem in handling calcium. n For people who had colon polyps removed, taking calcium supplements decreased the number of new polyps by 24% and cut the risk of recurrence by 19%, according to researchers at the University of North Carolina, Chapel Hill, School of Medicine. The study, published in the January 14, 1999 New England Journal of Medicine, was a first in crediting calcium with anti-cancer properties.

  The D Factor

  Without adequate vitamin D, your absorption of calcium slips and bone loss can accelerate, increasing the risk for fractures. Fifty percent of women with osteoporosis hospitalized for hip fractures at Brigham and Women's Hospital in Boston had a previously undetected vitamin D deficiency (Journal of the American Medical Association, April 28, 1999). University of Pittsburgh Cancer Institute researchers told participants at the April 14, 1997 meeting of the American Association for Cancer Research that vitamin D "significantly inhibits highly metastatic, or widespread, prostate cancer in animals," suggesting its potential for treating men with similar conditions. Few foods that Americans eat, except dairy, contain much vitamin D, but we can usually synthesize sufficient amounts from as few as five minutes' exposure to the sun. But as skin ages, its ability to act as a vitamin D factory decreases. According to Michael F. Holick, the director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center, upwards of 40% of the adult population over age 50 that he sees in his clinic are deficient in vitamin D. Recently, the National Academy of Sciences (the official body that decrees the required amounts of necessary nutrients) increased the daily recommendations of vitamin D to 600 IU for people over 71, 400 IU for those aged 51 to 70 and 200 IU for people under 50. The best dietary sources, apart from dependable supplements, are dairy and fatty fish like salmon. Four ounces of salmon provide about 300 IU.

  The Facts About Fats

  The American lust for low-fat, high-carbohydrate diets filled with sugary foods has exploded into nothing short of "obsession," according to experts at the General Research Center at Stanford University Medical Center (Am J Clin Nutr 70, 1999: 512S-5S). That mania oftens robs us of the crucial balance of omega-3 and omega-6 fatty acids typical of the Mediterranean diet that protect us from heart disease by controlling cholesterol and making blood less likely to form clots. These fatty acids cannot be made by the body but are critical for health: n Omega-3 fatty acid (linolenic acid) comes from fresh, deepwater fish (salmon, mackerel, sardines) and vegetable oils such as canola, flaxseed and walnut. n Omega-6 fatty acid (linoleic acid) found primarily in raw nuts, seeds and legumes and in saturated vegetable oils such as borage, grape seed, primrose, sesame and soybean. The American Heart Association recommends limiting total fat consumption to 30% of daily calories. Saturated fats like those in dairy and meat products as well as vegetable oil should comprise 10% of total calories; total unsaturated fat (fish oils, soybean, safflower nuts and nut oils) should be restricted to 20 to 22% of daily calories.

  Be Sure About B12

  Vitamin B12 presents a particular problem for the elderly because older digestive systems often don't secrete enough stomach acid to liberate this nutrient from food. (The elderly have no problem absorbing B12 from supplements, because it's not bound to food.) Vitamins generally moderate the aging process but, ironically, that process and the diseases that frequently accompany it affect vitamin metabolism (Schweiz Rundsch Med Prax 83, 1994: 262-6). And because of those changes, we need more of certain vitamins. This is the case for vitamins D, B6, riboflavin and B12. Crucial for health, B12 is necessary to prevent anemia, and, according to recent studies, needed (along with folate and B6) to help stave off heart disease. B12, with thiamine and niacin, boosts cognition (Adv Nutr Res 7, 1985: 71-100). Screening for vitamin B12 deficiency and thyroid disease is cheap and easy and can prevent conditions such as dementia, depression or irreversible tissue damage (Lakartidningen 94, 1997: 4329-32). In the January 5-12, 1999 issue of Circulation: Journal of the American Heart Association, the AHA urged doctors to screen levels of homocysteine (the amino acid byproduct of protein digestion that damages arteries, causes heart disease and, possibly, strokes) in patients at high risk for heart disease. They also recommended all Americans to up their daily levels of vitamins B6 and B12, as well as folic acid. Since fruits, vegetables or grains lack B12, vegetarians need B12 supplements. And they're a good idea for the rest of us, too.

  Folic Acid Benefits

  Folic acid made headlines in the early 1990s when the U.S. Public Health Service declared that "to reduce the frequency of neural tube defects [spina bifida, or open spine, and anencephaly, a lethal defect of the brain and skull] and their resulting disability, all women of childbearing age in the United States who are capable of becoming pregnant should consume .4 milligrams (400 micrograms) of folic acid per day." This recommendation followed voluminous research that showed taking folic acid was associated with a significantly reduced risk of birth defects. (The advisory is based on the fact that nearly half of all pregnancies are unplanned. If you think you are pregnant, consult your health practitioner for supplementary advice.)

  A Team Player

  Folic acid's efficacy intensifies when it works with other nutrients. Among many studies on the preventive powers of folic acid on birth defects, one published in The New England Journal of Medicine (327, Dec. 24, 1992: 1,832-1,835), disclosed an even greater decrease in neural tube defects when supplements of folic acid contained copper, manganese, zinc and vitamin C. As a warrior against homocysteine, folic acid joins the battalion of B12 and B6 in detoxifying this harmful protein. At the University of Washington's Northwest Prevention Effectiveness Center, researchers recently analyzed 38 published studies of the relationship between folic acid, homocysteine and cardiovascular disease and, according to associate professor Shirley A. Beresford, MD, folic acid and vitamin B12 and B6 deficiencies can lead to a buildup of homocysteine.

  Compelling Evidence

  Canadian researchers reported in the Journal of the American Medical Association (275, 1996: 1893-1896) that men and women with low folic acid have a 69% increase in the risk of fatal coronary heart disease. This 15-year study of more than 5,000 people stressed the need for dietary supplementation of folic acid. Folic acid also has been credited with the potential to protect against cancers of the lungs, colon and cervix. It appears to help reverse cervical dysplasia, the precursor cells to cervical cancer, especially for women taking oral contraceptives, which may cause a localized deficiency of folic acid in the cells of the cervix. According to Shari Lieberman, PhD, and Nancy Bruning, authors of The Real Vitamin & Mineral Book (Avery), folic acid derivatives work with neurotransmitters, the chemicals that permit signals to be sent from nerve fiber to nerve fiber. A lack of folic acid can cause some nervous-system disorders, such as depression, schizophrenia and dementia; it also may be related to some forms of mental retardation. Other supporting roles of folic acid, according to researchers: the formation of normal red blood cells, important for preventing the type of anemia characterized by oversized red blood cells; strengthening and improving white blood cell action against disease; limiting production of uric acid, the cause of gout.

  The Best Sources

  Many foods are rich in folic acid: beef, lamb, pork and chicken liver, spinach, kale and beet greens, asparagus, broccoli, whole wheat and brewer's yeast. But experts believe that only 25 to 50% of the folic acid in food is bioavailable. Processing also reduces an estimated 50 to 90% of its content. Folic acid supplementation overcomes these obstacles with little risk, as it has no known toxicity. Women taking folic acid who are current or former users of oral contraceptives may require additional zinc. And be sure to augment your folic acid supplement with its synergistic counterpart, vitamin B12.

  Focus on Fiber

  The American Heart Association came out squarely behind fiber in a June 16, 1997 issue of its journal Circulation: Double your daily intake to lower cholesterol and the risk of heart disease. The American diet is consistently low in fiber, notes Linda Van Horn, PhD, RD, author of the article. Twenty-five to 30 grams a day from foods (or supplements) are not only heart healthy but seem to aid weight control.

  Iron Problem

  Getting enough iron? An estimated 25% of adolescent girls in the United States are iron deficient, according to an October 12, 1996 issue of the British medical journal The Lancet, which reported that girls who took iron supplements performed significantly better on verbal tests than those who took a placebo. "Teenage girls should be regularly tested for iron deficiency because rapid growth and the onset of menstruation during puberty increase the body's need for iron," says Ann Bruner, MD, of the Johns Hopkins Children's Center and a lead author of the study.USDA data reveal that women up to age 50 also tend to get much less than recommended levels of iron, a lack of which leads to anemia, a deficiency of red blood cells, hemoglobin or volume of blood. For kids, deficiency is more common from six months to four years and during the rapid growth spurts of adolescence when the body is growing so quickly that the body's iron stores may sink to dangerous levels. Vegetarian women run the greatest risk for deficiency, as meat is iron-rich; foods like beans, grains and vegetables also contain some iron. Supplements, of course, supply easily absorbable iron. And to absorb iron from vegetarian sources, take vitamin C with your meals. That boosts the amount of this mineral you will take in. Bear in mind, however, that certain folks-older men and post-menopausal women-generally have adequate dietary supplies of iron. Of greater concern, in fact, is excessive iron, and for these folks iron-free multivitamin and mineral supplements are available.

  Ante Up the Antioxidants

  Antioxidant nutrients help protect the body from oxygen-scavenging molecules called free radicals. The products of pollution, the body's own metabolic processes and other sources, free radicals are linked to heart disease, cancer and other chronic health problems. The most important antioxidants, which include vitamin C, E, beta carotene, and selenium, are often lacking in the American diet. Plus, optimal amounts of vitamin E cannot be consumed from food. You need supplements. The bottom line: even though we live in a land of plenty, you can still miss vital nutrients. So make sure to consume these vital substances.

  Sprouts: Nutritional

  Source of Missing Nutrients In the search for the nutrients missing from America's diet, one big help is the sprout. The sprout is truly one of nature's heavyweights: fresh, tiny and moist, its power punch of vitamins, minerals, protein, chlorophyll and disease-busting phytochemicals land it in a weight class far beyond that of its full-grown competitors. Size does NOT matter to this nutritional giant. A championship belt currently wraps around the miniscule broccoli sprout, catapulted into the ring by Paul Talalay, MD, professor of pharmacology and molecular sciences at Johns Hopkins University. Dr. Talalay discovered that the seedlings contain substantially more of the cancer-fighting substance sulforaphane than mature plants (Proc. Natnl. Acad. Sci. USA, 94, 10367-10372). Sprouts, the quintessential health food of the Sixties, provide a wonderfully varied and versatile way to get your daily greens. Raw or cooked, strong or mild, vegetable and grass sprouts and their algae cousins add low-calorie texture to recipes and a rich, diverse complement of nutrients and fiber.

  Ancient Asia to the Modern Lab

  Asians stir-fried sprouts as one of the earliest fast foods as long as 5,000 years ago. The ancient Chinese relied on sprouts for year-round vegetables in colder regions of their vast country. Today, researchers studying sprouts and adult plants have identified their important chemoprotective and other health-bolstering substances. In Paul Talalay's research project at Johns Hopkins, scientists found that three-day-old broccoli sprouts contain up to 50 times more sulforaphane than mature plants, which prompts the body to produce an enzyme that prevents cancer tumors from forming. Uniform levels of the compound saturate the shoots, unlike the chemically uneven adult plants. The Brassica family of broccoli and cabbage is richly endowed with phytochemicals that also help reduce estrogen levels associated with breast cancer. Other phytochemical compounds in the Brassica family are associated with the prevention of stomach and lung cancers. Most of the initial landmark work on phytochemicals' cancer-fighting powers has taken place since 1989 under the aegis of the National Cancer Institute's "Designer Food Program," which isolated, for example, the isoflavones in beans that seem to neutralize cancer-gene enzymes.

  Strong Suit: Soy and Spirulina

  The isoflavones and phytosterols in soy produce an estrogenic effect that appears to relieve menopausal symptoms and help prevent breast cancer. Soy foods expert Mark Messina, PhD, has done extensive work on the subject, some of which has been published in the Journal of the National Cancer Institute 83, 1991: 541-6. Researchers also have synthesized a bone-strengthening form of soy isoflavones called ipriflavone, following impressive clinical trials in the treatment of osteoporosis (American Journal of Medicine, 95 [Suppl. 5A] (1993): 69S-74S). Spirulina and other micro-algae are fascinating organisms that inhabit a niche between the plant and animals kingdoms. Named for its tiny spirals, spirulina, a blue-green algae, grows in saline lakes but is cultured for maximum nutritional content. In her book Whole Foods Companion (Chelsea Green), Dianne Onstad notes that spirulina contains "the highest sources of protein, beta carotene and nucleic acids of any animal or plant food." Its nucleic acids, she says, benefit cellular regeneration; its fatty acids, especially GLA and omega-3 acids, make it one of the most complete foods. Sprouts, like any other produce, should be rinsed thoroughly before serving. People at high risk for bacterial illness-young children, the very elderly or folks with weakened immune systems-should limit their consumption of raw sprouts. But no matter how you eat them, you may find more spring in your step from these tiny, sprouting nutritional wonders.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=352)

  ---

  Defeat Depression
  

  Date: June 13, 2005 01:18 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Defeat Depression
  

  Defeat Depression

  by Cal Orey Energy Times, August 2, 1999

  Depression plagues the creative and the mundane. The disparate desperate driven to distress by depression include painters, poets, actors and musicians as well as truck drivers, clerks, electricians and physicists. The victim list encompasses Vincent van Gogh, Emily Dickinson, Audrey Hepburn, Virginia Woolf and Ludwig von Beethoven, as well as millions of other sharers of melancholy misery.

  More than 17 million American men and women experience depression in one form or another every year, according to the National Mental Health Association (NMHA) in Alexandria, Virginia. This includes the deeply destructive major, or clinical, depression, the wide mood swings of bipolar disorder (manic-depressive illness), and dysthymia, a milder, long-lasting form of emotional suffering.

  Twice as Many Women In the depression scenario, women suffer twice as much: Two times as many women as men endure clinical depression, reports the NMHA. The mood-deteriorating effects of the hormonal disruptions women are heir to may be partly to blame.

  According to the National Institute of Mental Health (NIMH), about one of 10 Americans wades through at least one depressive swamp sometime during his or her life.

  The good news: Research shows that diet and lifestyle can lower your risk of depression.

  Birth of the Blues

  Nowadays, mounting evidence suggests that depression may result more from physiological factors than psychological woes.

  Some of the hidden reasons why you may be depressed include: nutritional deficiencies, exacerbated by overdosing on too much caffeine, sugar, alcohol and high fat foods; allergies; anxiety and chronic stress; and a chemical imbalance in the brain's gray matter. According to the NMHA, people with depression often possess too little or too large a quantity of the neurotransmitters norepinephrine, serotonin and dopamine. Changes in levels of these brain chemicals may cause, or contribute to, clinical depression.

  The NMHA also reports that an imbalance of melatonin, a chemical made by the body's pineal gland (located at the base of the brain), contributes to a form of wintertime depression called seasonal affective disorder (SAD). This hormone is made at increased levels in the dark. Therefore, the body may oversupply this hormone during winter's shortened daylight hours.

  Plan B

  Since the B vitamins are often involved in the production of energy, and a large component of depression may encompass the inability to get out of bed and deal with the world, experts believe that at least some of the signs of depression are linked to B deficiencies. For instance, studies cited in the Encyclopedia of Natural Medicine (Prima) by Michael Murray, ND and Joseph Pizzorno, ND, demonstrate that folate deficiency and lack of vitamin B12 can compromise mental health (Drugs 45, 1993: 623-36; Lancet 336, 1990: 392-5).

  Inositol: This vitamin is also part of the B vitamin complex, and it, too, has shown its ability to lift spirits. Research work in Israel shows that daily inositol given to 28 depressed patients for four weeks produced an overall positive effect. (Eur Neuropsychopharmacol 7:2, May 1997: 147-55). Inositol is found in whole, unprocessed grains, citrus fruits (except lemons) and brewer's yeast.

  NADH: Allan Magaziner, DO, in his book The Idiot's Complete Guide To Living Longer & Healthier (Alpha), reports that brain energizing NADH, a metabolite of vitamin B3, enhances the production of the key neurotransmitters dopamine, noradrenaline and serotonin. "In a recent clinical trial," he claims, "nearly all patients given NADH for depression reported improvement in their symptoms and the absence of side effects or adverse reactions."

  Moody Spotlight

  Another substance winning the spotlight for its effect on mood is SAM-e: S-adenosylmethionine. In New York on February 24, a symposium coordinated by the American Health Foundation met to hear researchers present information from studies of SAM-e's ability to possibly ease depression.

  "SAM-e is a natural product. You and I have it but as people age it declines in production in the body. And that's why we believe supplementation in older people is a beneficial means of bringing that back up and helping people that have depression," said the lead symposium researcher, John H. Weisburger, PhD, MD, Director Emeritus, American Health Foundation in Valhalla, New York.

  Another researcher, Teodoro Bottiglieri, PhD, Associate Professor of Biomedical Studies and Neurology, Director of Neuropharmacology at Baylor University reported: "SAM-e has been shown to enhance brain dopamine and serotonin neurotransmitter metabolism and receptor function. It may also aid in the repair of myelin that surrounds nerve cells. These mechanisms are likely to be responsible for the antidepressant effect of SAM-e."

  (Bottiglieri is co-author with Richard Brown, MD, and Carol Colman of Stop Depression Now, a report on the powers of SAM-e just published by G.P. Putnam's Sons.)

  SAM-e was first touted as an antidepressant in Italy in 1973. It's been reported that nearly 40 clinical trials demonstrate its beneficial effects as a natural antidepressant.

  For instance, an analysis of more than 1000 people suffering depression showed that the effect of antidepressants in patients taking SAM-e was 17% to 38% better than dummy preparations. Conventional antidepressants show a 20% effectiveness rate (Bressa G. Acta Neurol Scand S154, 1994: 7-14).

  5-HTP: Another popular supplement to boost mood and relieve depression is hydroxytryptophan. "This medication is actually a brain chemical that is metabolized from tryptophan into serotonin," says Magaziner. And since low serotonin levels have been linked with depression, and certain prescribed medications may up serotonin levels, 5-HTP is in demand.

  "One of the more impressive studies supporting the efficacy of 5-HTP for depression evaluated 100 people who had previously found conventional antidepressant therapy to be inadequate. Forty-three of these folks reported a complete recovery, and eight showed significant improvement," reports Magaziner. Not only has 5-HTP been shown to work slightly better than drugs known as SSRIs (these include Prozac), he adds, it has fewer side effects than standard antidepressants, too. DHEA: Medical experts also believe that levels of the hormone DHEA (dehydroepiandrosterone) may influence mood. Ray Sahelian, MD, in his book All About DHEA (Avery) reports an interesting study conducted by Dr. Owen Wolkowitz of the Department of Psychiatry, University of California, San Francisco. A group of six depressed middle-aged and elderly individuals who took DHEA found that within a month they had better memory and mood. (Biological Psychiatry 41, 1997: 311-18.) "In addition," adds Sahelian, "other studies have also found that DHEA increases energy levels and a sense of well being." But follow package directions: Some people complain of greater irritability and overstimulation with DHEA, when they take large amounts.

  Herbal Relief

  St. John's wort: still the most touted natural therapy for defeating depression. In Europe, 23 clinical studies, reviewed in the August 3, 1996 British Medical Journal, found that this herb, also known as Hypericum perforatum, can be helpful in alleviating cases of mild to moderate depression. The work, which included 757 patients, has shown that hypericum produced fewer side effects than conventional anti-depressants.

  Although experts have never satisfactorily explained exactly how St. John's wort benefits the brain, some theorize that it boosts serotonin levels. And it can help SAD sufferers.

  "In a recent study of 20 people with SAD, four weeks' worth of St. John's wort significantly alleviated feelings of depression. Those people who added full-spectrum lights to the treatment program gained an even greater benefit," notes Dr. Magaziner.

  Valerian: Anxiety and stress, which can cause depression and insomnia, may be helped by this herb, says the prolific Dr. Sahelian in his book Kava: The Miracle Antianxiety Herb (St. Martin's). In 101 Medicinal Herbs (Interweave), Steven Foster reports that "Ten controlled clinical studies have been published on valerian...one of which suggests that valerian should be used for two to four weeks before daily mood and sleep patterns improve."

  Amino Acid Help

  Amino acids, the building blocks of protein, may also help improve mood. (For more on protein, see page 65.) These chemicals are used by the body to construct neurotransmitters, brain chemicals that facilitate mental activity.

  For instance, the amino acid L-tyrosine is necessary for the formation of transmitters adrenaline and dopamine. This substance, therefore, is given to alleviate depression and anxiety.

  The substance L-dopa which is given to victims of Parkinson's disease is concocted from tyrosine. And several antidepressants alleviate bad moods by boosting the interaction of brain chemicals related to tyrosine.

  In addition, since tyrosine is used to make adrenaline, this amino acid may be helpful for folks trying to cope with the mood problems related to stress.

  Another amino acid that experts believe useful for better moods, L-methionine, is used by the body to make choline, a crucial substance for brain function. (Choline goes into the formation of acetylcholine, a neurotransmitter.)

  Methionine has been given to people suffering from schizophrenia and depression as well as to those with Parkinson's. Methionine plays a number of crucial roles in the brain and body since it helps form other vital proteins.

  Depressive Smoking

  For those concerned about preserving a positive mood, researchers are positive that smoking worsens depression. A study at the Department of Behavioral Services at the Henry Ford Health System in Michigan found that daily smokers run twice the risk for major depression compared to those who only smoked occasionally.

  Unfortunately, the investigators found that not only did smoking seem to lead to depression, depression, in turn, led to more smoking (Archives of General Psychiatry, 2/99).

  "Smokers who have depression tend to see their smoking become a daily habit and it may be because they use nicotine to medicate their depressed mood," reported Naomi Breslau, PhD, who headed the research. Over a five year period, the researchers looked at about a thousand young people aged 21 to 30. They found that daily smokers generally start smoking in adolescence, and those who report early depression are three times as likely to eventually become daily smokers.

  If you're feeling down, don't give up hope. Although depression can prove to be a depressingly complicated malady, daily, healthy habits can offset its effects. Getting consistent exercise, dousing your cigarettes and turning to herbal and nutritional help to treat mild depression may defeat those blues.

  
  
  --
  Vitanet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=329)

  ---

  Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
  

  Date: June 13, 2005 10:31 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
  

  Botanical Arsenal by Fred Thomas Energy Times, May 3, 1999

  The complexities surrounding the various types of cancer stem from the variety of ways in which these diseases can wreak their havoc. Luckily, the equally complex world of plants contains novel compounds that can help our bodies fight off cancer's deadly progress.

  Research Expands

  Research into these botanical compounds is mushrooming. An example: The mighty maitake, a fungus with flair, alternately known as the king (it can grow as large as a basketball, worth its weight in silver to the ancient Japanese); the prince; the Hen of the Woods (it sticks out of from trees when it grows in the wild); and the dancing mushroom to those who leaped for joy when they found one growing in its native northeastern Japan.

  Researchers today dub it with a new moniker: Herbal Heavyweight.

  Mushroom with Potential

  The maitake, with such other medicinal mushrooms as shiitake and reishi, historically has been eaten to promote general well-being and vitality. In the modern lab, however, scientists focus on the potent immune enhancing powers of maitake, which spotlight its cancer fighting potential.

  Twenty years ago, maitake, Grifola frondosa, was an obscure, largely unavailable mushroom. A series of significant Japanese studies then catapulted it into prominence-and popularity.

  Maitake Magic

  Hiroaki Nanba, PhD, of the department of immunology at Kobe Women's College of Pharmacy on Kobe, Japan, and a leading international researcher on maitake, conducted the preliminary tests on the mushroom, demonstrating that it stimulates immune function and inhibits tumor growth.

  In 1986, Dr. Nanba fed powdered maitake to mice injected with tumor cells; 86.3% displayed inhibited tumor growth.

  Dr. Nanba and his colleagues went on to run additional mouse tests, finally reporting that this potent mushroom "directly activates various effector cells (macrophages, natural killer cells, killer T-cells, etc.) to attack tumor cells."

  From then, maitake mushrooms were headed to fame as cancer ninjas.

  Stoking The Immune Engine

  Like other mushrooms, maitake is rich in complex polysaccharides, immunomodulators that successive tests after Dr. Nanba's have shown to be effective in cancer and AIDS treatment.

  The polysaccharides in maitake have a unique structure, rendering them some of the most powerful to be studied (Chem Pharm Bull 1987:35:1162-8).

  What makes maitake a particularly hot property is beta-D-glucan, its primary polysaccharide. Studies show that the body absorbs it readily, at which point it effectively stimulates interleukin-1, natural killer cells and macrophages, anti-tumor warriors that battle solid cancers (Chemotherapy 1990;38:790-6; also International Conference on AIDS, Amsterdam, 1992).

  Effective And Safe

  In addition to lab tests, trials on people have shown that maitake may offer powerful therapy against liver and stomach cancer (studies in China), breast and colon cancer (US research) and Kaposi's Sarcoma, the virulent cancer attacking AIDS sufferers.

  Importantly, studies show that no side effects or interactions accompany maitake's efficacy.

  Maitake fortunately has won the interest and enthusiasm of the scientific community. Currently, researchers at the Cancer Treatment Centers of America, headed by Denis Miller, MD, are completing an exhaustive test of the anticancer and immunostimulatory actions of maitake on folks with advanced colorectal cancer. These investigators hypothesize that the polysaccharide beta-glucans derived from the fruitbody of maitake fight tumors and boost immune function. "Though it cannot be said that maitake ...[is] the cancer cure," said Dr. Nanba in his closing remarks at the Adjuvant Nutrition in Cancer Treatment Symposium in Tampa, Florida, in October 1995, "one can safely say that they do maintain the quality of life of patients and improve the immune system, resulting in the possible remission of cancer cells with no side effects."

  More Bodily Benefits

  Maitake maven Dr. Nanba also has tested-with strongly positive results-the effect of maitake on blood glucose, insulin and triglycerides in mice, whose levels of all three substances declined when they were fed the mushroom (H. Nanba working paper, Anti-Diabetic Activity by Maitake Mushroom, 1994).

  With colleagues, Dr. Nanba showed that maitake lowered blood pressure in hypertensive rats (Chem. Phann. Bu//36:1000-1006,1988). Other studies suggest it may accelerate weight loss.

  This admirable adaptogen (meaning it helps the body adapt to stress and normalize its functions) is water soluble and may be eaten in food or taken as a supplement. Vitamin C is believed to intensify maitake's beta-glucans and enhance their absorption.

  Tea Time

  It's not just what you eat that may help protect against cancer, but what you drink as well. Research from China and Japan, where tea is the everyday drink and rates of several cancers like breast and prostate are lower, may persuade you to turn over a new leaf in your own beverage choice. One of the first studies to spark interest in tea came from Shanghai (Journal of the National Cancer Institute, June 1, 1994), where people who drank two to three cups a day were found to have about a 60% reduction in the risk of cancer of the esophagus. The reason: tea leaves contain compounds called polyphenols, potent antioxidants.

  In fact, in tests at the University of Kansas, three of these, known as catechins, far outshone the common antioxidant vitamins C and E. Clinical trials are just starting, but early results are encouraging. A team of Chinese scientists reported that in a third of people with precancerous mouth sores who drank three cups of a mixture of green and black tea the lesions shrank significantly.

  Researchers at the Saitama Cancer Center in Japan found that green tea seems to improve the prognosis of breast cancer. They followed a group of women with early-stage tumors for seven years. Those who drank more than five cups of green tea a day were only half as likely to suffer a recurrence as patients who consumed fewer than four cups a day.

  Lung Help

  And at the University of Indiana, toxicologist James Klaunig found that the lungs of cigarette smokers who drank the equivalent of six cups of tea a day suffered 40 to 50 percent less damage from the toxins in smoke, potentially lowering their risk of lung cancer and other pulmonary problems. Simultaneously, research from Purdue University suggests tea's cancer-discouraging powers go beyond being an antioxidant. Scientists Dorothy and D. James Morre showed that a tea catechin dubbed EGCG inhibits a growth-promoting enzyme on the surface of many cancer cells-happily without affecting normal cells. And researchers at the Ohio State University College of Medicine found that EGCG counteracted another enzyme, urokinase, that helps cancer cells spread. To top it off, Mayo Clinic scientists recently showed that EGCG prompted prostate cancer cells to commit suicide (Cancer Letters, Aug. 14, 1998).

  Tea Research

  So far, most tea research has focused on green tea, and investigators agree it's more potent than the black tea most Americans favor. But because both kinds come from the same plant, Camellia sinensis (it's the processing that makes the difference as black tea is fermented, green tea isn't) both contain cancer-fighting polyphenols, just in different quantities. As long as the tea you drink (even decaffeinated) is fresh brewed, it's likely to provide some benefit; powdered and prepared teas probably don't. And adding milk may dilute the effect.

  Astragalus Against Tumors

  Astragalus, an herb commonly used in Asia to boost stamina, has impressed western doctors for its potential for helping people cope with chemotherapy. As John Diamon, MD, W. Lee Cowden, MD and Burton Goldberg point out in the Definitive Guide to Cancer (Future Medicine), "Astragalus appears to protect the liver against the harmful toxic effects of chemotherapy and may be effective in treating terminally ill liver cancer patients." (They cite a study in the Jrnl of Ethnopharmacology 1990, 30:145-149.) In addition, they point out, research in Japan supports using a ginseng-astragalus combination to improve the function of natural killer (NK) cells which can boost immunity (Japanese Jrnl of Allergy, 37:2, 1998, 107-114).

  Other studies confirm astragalus' potential in fighting off cancer. Research at the General Hospital of PLA, Beijing, showed that flavonoids (pigments) in astragalus could help protect cell membranes from oxidative damage caused by ultraviolet exposure (Chung Kuo Chung Yao Tsa Chih, 21(12):746-8; 1996 Dec).

  A study of laboratory animals at Cunma University in Maebashi, Japan, found that Astragalus could help preserve immune function against the harmful side effects of chemotherapy (Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 15(2):101-3, 1995 Feb).

  Garlic Benefits

  Like a flame attracting moths, garlic bulbs have irresistibly drawn the attention of medical researchers. A study at Aarhus University, Denmark, found that skin cells in laboratory dishes treated with garlic supplements lived longer, healthier lives than untreated cells (Jrnl Ethnopharm, 1994. 43:125-133).

  Meanwhile, a long list of research demonstrates that garlic's phytochemicals may fight tumors and reduce the carcinogenicity of the pollutants and chemicals that assault us daily. A study in China reported in the American Journal of Chinese Medicine showed that garlic helped slow tumors in lab animals (1983, 11:69-73). Another study in the Journal of Nutrition found that compounds in garlic could "suppress the growth of human colon tumor cells" (126, 1355-1361).

  Added to those benefits, Robert A. Nagourney, MD, reports in the Journal of Medicinal Food (1:1, 1998, 13-28), garlic may "modify the carcinogenicity of foodstuffs." In other words, studies show that garlic can make chemicals in foods like pork less likely to cause your cells to become cancerous. (Ind J Physiol Pharmacol, 39:347-353).

  DNA Protection

  DNA, the stuff that genes are made of, face constant threats from free radicals, caustic molecules that can alter cellular structure and possibly cause genetic mutations that lead to cancer. But research into what are called oligomeric proanthocyanidins (OPC), flavonoids (pigments) derived from fruits vegetables, grape seed extract and the bark of maritime pine trees shows that OPC may be able to shield DNA from injury.

  In particular, studies of a grape seed extract called Activin have demonstrated this substance can help liver cell DNA escape a destructive process called peroxidation (FASEB, 11:3, 2/28/97).

  In these experiments, Activin demonstrated the ability to inhibit the growth of tumor cells as well as slow the replication enzymes of HIV viruses. This protective ability proved to be more potent than that of vitamin C, beta carotene and vitamin E.

  Future Promise

  What does the future promise to reveal? Scientists believe that many unexamined plants probably contain undiscovered phytochemicals that hold great potential for helping us fight the cancer epidemic.

  Certainly, if the next few years produce as many results as the past decade, the next millennium will witness a long line of cancer-prevention discoveries. Before long, you should be able to take advantage of these potent substances.

  As you gulp your garlic, tip your tea cup, mull your maitake, acquire Activin and await your astragalus, you may meditate on what may soon be added to our growing anti-cancer arsenal. Undoubtedly, scientists with a botanical bent will be uncovering more coveted anti-cancer secrets before too long.

  
  
  --
  Vitanet ®
  
  

  Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=326)

  ---

  Bone Power - Natures Plus
  

  Date: June 11, 2005 04:41 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Bone Power - Natures Plus
  

  Bone Power by no author Energy Times, May 1, 1997

  Patricia Q. stopped smoking 20 years ago. At 61, she is active, tries to exercise regularly, eats properly and takes a multivitamin. Most would consider Patricia's lifestyle a sufficient safeguard against the diseases of aging. But one debilitating possibility still concerns her: Osteoporosis-bone thinning. She worries that her bones may have begun weakening almost a decade ago. Although her good health habits can slow the demineralization of her bones, osteoporosis may still take its toll. And as her neck and back begin to obviously round, a possible sign of bone weakness, Patricia frets about her future.

  The weakening of bones brought on by age makes them more prone to fracture. One of every two women older than age 50 suffers an osteoporosis-related fracture during her lifetime. Osteoporosis literally means "porous bones," bones that deteriorate and particularly increase the risk of damage to the hip, spine and wrist. In extreme cases, everyday activities assume danger: fractures can result from simply lifting a bag of groceries or from what would otherwise be a minor fall. Some women, fearful of fractures, eliminate many seemingly innocuous activities from their daily lives. Their fear is well founded. Complications from these fractures are a major killer of women.

  As women grow older, the risk grows, too. Ten million individuals already have the disease, and 18 million have low bone mass, placing them at risk for osteoporosis.

  But research shows that osteoporosis may be preventable and controllable. Regardless of age, eating right, getting enough calcium and performing weight-bearing exercises, can lower your risk for this disease.

  Understanding Your Bones

  Bones are not static structures but living tissue constantly reformed in a process called remodeling. Every day old bone is removed and replaced with new bone tissue. When more bone is broken down than is replaced (demineralization), bones weaken. When the structure loses sufficient density, you face eminent danger of a fracture.

  Generally speaking, bones continue to increase their density and calcium content until you reach your 30s, at which point you probably have attained your peak bone mass. Afterward you may either maintain this mass or begin to lose calcium yearly, but you rarely can increase bone density. The loss of bone density can increase at menopause, when your body ceases producing estrogen, a hormone required to improve bone strength. In addition, some medications, used for a long period, compromise bone density.

  Stop Calcium Loss

  Eating a diet rich in nutrients that help your bones stay strong should be the first step in stopping or slowing the process of osteoporosis. Calcium, magnesium, vitamin D, phosphorus, soy-based foods and fluoride compose the major nutrients that strengthen bone.

  At this moment, 98 percent of your body's calcium resides in your bones, the rest circulates in the blood, taking part in metabolic functions. Because the body cannot manufacture calcium, you must eat calcium in your daily diet to replace the amounts that are constantly lost. When the diet lacks sufficient calcium to replace the amount that is excreted, the body begins to break down bone for the calcium necessary for life-preserving metabolic processes.

  Calcium in the diet can generally slow calcium loss from bones, but it usually doesn't seem to replace calcium already gone. The National Institutes of Health recommend 1000-1200 milligrams of dietary calcium per day for premenopausal women and 1200-1500 milligrams for menopausal and postmenopausal women

  Good sources of calcium include milk and milk products, yogurt, ricotta, cheese, oysters, salmon, collard greens, spinach, ice cream, cottage cheese, kale, broccoli and oranges.

  If you cannot tolerate dairy products, calcium supplements are an easy way to consume calcium. Take supplements with a meal to aid absorption of calcium from the stomach.

  In Total Health for Women, Dr. Kendra Kale, clinical assistant professor of medicine at the University of Pennsylvania School of Medicine, urges women to read supplement labels. Scrutinize the fine print to see how many grams are considered "elemental"or "bioavailable"-the form of calcium your body will absorb. If you're taking a 750 milligram supplement, chances are only 300 milligrams are elemental. You should also check that the pill will dissolve within 30 minutes and meets the United States Pharmacopoeia (USP) standards. If tablets do not break down within 30 minutes, they may pass through you unabsorbed and you won't digest the calcium from them that you need.

  Absorbing calcium from your digestive tract also requires the presence of vitamin D. Ten to 15 minutes of sun exposure daily usually satisfies vitamin D requirements since most people's bodies can use sunlight to manufacture this substance. So walking to work, or going outside for lunch should supply sufficient ultraviolet light to facilitate calcium absorption.

  As we age, however, our body's ability to produce vitamin D gradually diminishes. Our diets can make up the difference: Good dietary sources of vitamin D include egg yolks, liver and fish or nutritional supplements. Many foods, like milk, are supplemented with vitamin D.

  Magnesium is another mineral that helps to build bones. Found in leafy, green vegetables, nuts, soybeans, seeds and whole grains, your daily requirement of magnesium should be about half of your calcium intake.

  Absorbing calcium for bone health also requires phosphorus, but be careful not to get too much of a good thing: excess phosphorus can actually increase your body's need for calcium. This can present a problem for people who drink bottle after bottle of cola soft drinks or who eat an abundance of processed foods which are often high in phosphorus.

  New Soy Research

  New research suggests that soy foods, like tofu or soy milk may be vital for preserving bones. A study of more than 60 postmenopausal women who consumed either diets rich in soy's isoflavones or milk protein found that eating soy restored calcium to some of the women's bones. Even though the researchers didn't think such a replacement due to soy was even possible!

  The researchers at the University of Illinois believe that isoflavones behave in the body in some of the same ways that estrogen does. The study measured bone density at the lumbar spine, a part of the body at the small of the back that is liable to fractures due to osteoporosis.

  Fluoride: Not Just For Teeth

  Although most people associate the mineral fluoride with strong teeth, fluoride is just as important for bone strength. Surveys report that osteoporosis is reportedly less common in communities that drink fluoridated water. Fluoride combines with calcium in the bones to slow mineral loss after mid-life. Good sources of this mineral include fish, tea and most animal foods.

  Cut Back on Alcohol and Coffee

  According to the National Osteoporosis Foundation, consuming lots of caffeine is thought to increase the calcium excreted in your urine. In addition, high levels of protein and sodium in your diet are also believed to increase calcium excretion. And although more studies of protein and sodium are needed to precisely determine how these substances influence calcium loss you should limit the caffeine, protein and salt you take in.

  On top of those findings, researchers say that the diuretic action of alcohol and caffeine speed skeletal calcium loss. They believe alcohol may interfere with intestinal absorption of calcium.

  Pumping Up

  Along with a bone-friendly diet, your exercise program should also be designed to preserve bone. Weight-bearing exercise-exercise that places stress on the bones-strengthens bone density and wards off osteoporosis. Weight-bearing exercises include weight lifting, walking, jogging and jumping rope.

  Exercise possesses many benefits for preserving bone, according to Miriam Nelson, Ph.D., author of Strong Women Stay Young. Among them: exercise can help you retain the balance necessary to resist falls and strengthen the muscles that keep you erect. Studies performed on women of all ages found that by doing strength training exercises two times a week for a year, without use of estrogen or hormone replacement therapy (HRT), women, on average, added three pounds of muscle and lost three pounds of fat. They were also 75 percent stronger with improved balance and bone density.

  Although strength training can be performed by anyone at any age, Nelson recommends that if you have an unstable medical condition or if you have recently undergone surgery, wait until you recover and speak with your doctor before beginning an exercise program. If you have not exercised in a long time, consult a health practitioner knowledgeable in sports medicine before beginning an exercise program.

  Other Options

  Drug therapies are now available to combat osteoporosis. One of the most popular is HRT, which supplies estrogen to women undergoing menopause. However, medical experts are still arguing over HRT 's possible role in increasing your risk of cancer, particularly breast cancer.

  According to Jan Rattner-Heilman, co-author of Estrogen, the Facts Can Change Your Life, the conflicting studies that balance the benefits and risk of HRT are bound to confuse the average consumer. Estrogen is recommended to prevent bone loss and forestall heart disease and possibly Alzheimer's disease. Most women take estrogen to ease the discomforts of menopause such as hot flashes, and many experts do not believe that it unduly increases the risk of breast cancer for those at low risk.

  Heilman warns, however, that estrogen probably should not be taken by women especially at risk for breast cancer risk or those who are already suffer the disease.

  Patricia Q. is reluctant to try HRT. "I'm at risk for breast cancer-my mother had it-so I won't take estrogen. I'd rather do what I can without medications. My preference is to watch my diet and exercise as much as I can. That gives me my best chance to avoid osteoporosis."

  Doctor Nelson agrees with this perspective She believes that exercise possesses enough benefits to make it the treatment of choice. "The difference between estrogen and strength training is that strength training has a huge spillover effect; you aren't just decreasing one type of disease. You become stronger with more muscles and less fat, and you become more fit. This decreases your chances for many types of diseases, not just osteoporosis. It can decrease risks for heart disease, diabetes, sleep disturbances, hypertension and more."

  If you believe you are at risk for osteoporosis, ask your doctor about the benefits of bone mineral density screening. DEXA scan (dual energy x-ray absorptiometry) measures the bone density in a 15-minute test. But the test is expensive: the cost of this test ranges from $75-200 or more and may not be covered by your health insurance. But financial help may be on the way. A Bone Mass Standardization Act has been introduced in Congress to ensure that the cost of bone mass measurement is covered under Medicare and that standards for coverage are clear and consistent for anyone with medical insurance.

  Fighting Osteoporosis at Different Ages

  Childbearing years (30-40): These years are particularly important for preserving bone through exercise and good nutrition. Eat plenty of low-fat dairy products, vegetables and soy. Perform weight-bearing exercise such as walking, jogging and weight lifting to attain the greatest amount of bone and muscle possible. Being active reduces risk of injury and makes you stronger. If you smoke, now's the time to stop.

  Menopausal years (late 40s-50s): During this time, muscle, bone and estrogen decreases. Minimize loss through diet, walking and weight lifting. Your exercise intensity may have to be decreased but you should not stop being physically active.

  Post Menopause (over 60): Focus on reducing your risk of falling. Minimize balance problems and increase muscle strength through exercise.

  
  
  --
  Vitanet ®
  
  

  Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=291)

  ---

  Stevia, Xylitol Sugar alternatives ...
  

  Date: June 09, 2005 06:15 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Stevia, Xylitol Sugar alternatives ...
  

  Xylitol

  Stevia

  Sugar Solution by Kristin Daniels Energy Times, January 4, 2002

  Sugar Solution by Kristin Daniels

  Low blood sugar-a blood sugar recession-can make the good times recede. While you can't live without blood sugar, too much or too little wreaks havoc on your body and mind. And when blood sugar dips low enough to cause hypoglycemia you may feel like your emotions have been shredded. Knowing how the body regulates blood sugar allows you a measure of control in keeping blood sugar in the proper groove, and makes life a little sweeter. Hypoglycemia occurs when you feel dragged out because of low blood sugar. Ironically, this low blood sugar syndrome may be caused by an overabundance of sugar in your meals and snacks. Those who point to hypoglycemia as a widespread problem claim that up to two of three women in America suffer from hypoglycemia. That would make it an epidemic of monstrous proportions. In a survey of 1000 folks complaining of hypoglycemia, published in the Hypoglycemia Support Foundation's winter 2000 edition, researchers found that low blood sugar sufferers complained of hypoglycemic discomforts in several main categories: 94% of the people in the study reported nervousness, 89% mentioned irritability, exhaustion affected 87%, depression struck 86% and drowsiness hit 73%. Other miseries included fatigue, cold sweats, tinnitus (ringing of the ears), rapid heart rate, blurry or double vision, confusion, sudden hunger, convulsions, sweating, sleeping problems, paleness, muscle pain, memory loss, crying jags, fainting and dizziness.

  Body of Evidence
  Hypoglycemia may result from munching endless sweets and never exercising (physical activity improves your body's handling of sugar). Many sufferers of hypoglycemia may view it as a disease, but the experts pigeonhole it, technically, as a condition or syndrome. R. Paul St. Amand, MD, Professor of Endocrinology at UCLA, points out that "in certain people, the body is unable to process carbohydrates without adverse consequences. Hypoglycemia, or low blood sugar, is the name often used to denote a whole disease. But more accurately it is only one of a cluster of symptoms that together make up a syndrome." According to herbalist Cynthia Hartson, ND, at Better Health Chiropractic and Natural Family Health Care in Mission Viejo, California, when you eat too many processed foods you set yourself up for a big fall in blood sugar. "...As with many conditions out there, you don't catch diseases, this one or any; you create an environment in your body that allows these symptoms (and conditions) to occur." Your body breaks down carbohydrates, including those in vegetables, fruits, breads and grains, into simpler sugars. As these carbohydrates pour into the blood in the form of glucose, cells in the pancreas secrete the hormone-like substance insulin. Insulin is supposed to persuade cells to take up this in-flow of glucose and use it as fuel. But if, during this process, blood sugar drops too low, the pancreas releases glucagon, which stimulates the release of glucose into the blood to bring blood sugar levels back up. Overindulging in sweets and processed foods may upset this blood sugar balancing act. Americans consume about 120 pounds of sugar per person annually, a voluminous avalanche compared to preindustrial times when we only took in about seven pounds a year. When you eat your way through this much sugar, Dr. St. Amand claims, your body's "...excess amounts of carbohydrates (generate) an overproduction of insulin. As your blood sugar drops, your brain tunes out. Because a massive amount of carbohydrates drives your insulin and glucagon down, the fats (stored as carbohydrates) in your body can't be released (for energy) and you crave more carbohydrates." As you continue to consume large amounts of carbohydrates, the pancreas secretes greater amounts of insulin to properly transport the excesses of circulating blood sugar. Eventually, every time you eat sugar, your pancreas may release excessive insulin, which drives and keeps your blood sugar low enough to make you feel like lying down in a corner and telling the world to go away. And there's more bad physiological news: Your adrenal glands respond to this stress by producing adrenaline and dumping it into the bloodstream in overabundance, causing anxiety, trembling and panic attacks: frequent signs of a hypoglycemic reaction. Adrenaline is supposed to stimulate the liver to release glycogen (stored sugar) to get your blood sugar back to a functioning level. But once again, as your sugar cycle degenerates, the pancreas increasingly produces more insulin to drive down your blood sugar level. Your blood sugar may drop and stay down.

  Numbers Game
  Many conventional doctors dismiss hypoglycemia as an illusion. But Dr. St. Amand states that doctors are "hung up on numbers." The glucose tolerance test, typically used to diagnose hypoglycemia, is based on numbers and the numbers often don't add up. Signs of hypoglycemia typically show up to two to three hours after a meal or snack containing lots of processed foods, when there is a rapid release of sugar into the small intestine, followed by rapid glucose absorption into the bloodstream and the consequent production of a large amount of insulin. These reactions occur so rapidly and unpredictably that catching them in a glucose tolerance test is often impossible. (Of course, see your health practitioner if you suffer persistent health problems that may be caused by a serious underlying condition or disease.)

  Diary of a Maddening Condition
  Keeping a food diary can help you discover what foods set off your hypoglycemia. Be honest, and record everything: your food, drinks, even breath mints! Note the time you eat, the time you sleep, the exercise you do, and your moods to see what triggers low blood sugar. Once you identify your triggers, remove them. When recommending ways to dodge hypoglycemia, Dr. St. Amand says, "It is not what you add but what you remove" that's most important. Items that often cause problems include:

• * Sugar (obviously) of all kinds: table sugar, corn syrup, honey, sucrose, glucose, dextrose or maltose.
• * Starches such as potatoes, rice, pasta and processed white breads.
• * Fruit juices.
• * Caffeine (coffee, tea, chocolate and soft drinks), which intensifies the action of insulin. The National Hypoglycemia Association says that foods which many hypoglycemia sufferers find to be helpful are those high in soluble dietary fiber and complex carbohydrates: whole grains, legumes and vegetables, which may be absorbed more gradually than processed items. Slower carbohydrate absorption may help prevent the major swings in blood sugar levels that foments hypoglycemia. Eating smaller meals and snacking often may ease blood sugar fluctuations. Incorporate fats into your snacks to decrease the flow of carbohydrates into your bloodstream and decrease carbohydrate cravings. Whole-wheat crackers with natural peanut butter, vegetables dipped in organic olive oil, packaged nuts and seeds, rice cakes, and soy cheese may slow sugar absorption. Your food diary should also record your activity level, the amount of water you drink, and indicate the times you feel stressed. While your diary may show that the stresses and lifestyle items that most frequently trigger your hypoglycemia are different than those that cause problems in others, you will probably discover that exercise significantly helps to dispel low blood sugar discomforts. Exercise tones your muscles, improves circulation and aids in digestion. It increases circulation and helps your muscles metabolize sugars more effectively.

  Review Time
  Ask your relatives to find others in your family who suffer diabetes, hyperinsulism or hypoglycemia. Roberta Ruggiero, president of the Hypoglycemia Support Foundation, Inc., and author of the book The Dos and Don'ts of Low Blood Sugar (Lifetime), notes that genetics plays a large role in reactive hypoglycemia. "In a survey of confirmed hypoglycemics," she states, "it was found that approximately 64 percent of them had one or more family members who had been diagnosed with diabetes." If you know someone in your family suffers this kind of problem, you can find it helpful to see what works for them to relieve the discomforts of low blood sugar. And you can share with them what works for you. Together, you can slip the shackles of hypoglycemia and sweeten your days.
  
  --
  VitaNet ®
  VitaNet ® Staff
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=263)

  ---

  VITAMIN A and CAROTENOIDS - What are they good for?
  

  Date: June 09, 2005 09:27 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: VITAMIN A and CAROTENOIDS - What are they good for?
  

  Vitamins

  In 1912, Casimir Funk coined the term 'vitamine' to refer to a 'vital factor' he proposed was an essential component present in foods. His conjecture dovetailed with other research, leading to the isolation in the 1930's and 40's of the compounds we now call vitamins.

  Vitamins are chemical substances which play a variety of roles in the human body. They are core components of any nutritional supplementation program.

  While many people are aware of vitamins as necessary substances for good nutrition, few have a grasp of the extraordinary complexity of the roles they play in our bodies. As you'll see below, vitamins are involved in trillions of biochemical interactions every minute to keep us alive and functioning. For example, B-vitamins are converted into coenzymes which are directly necessary for the production of ATP energy from food, a process that goes on continuously in every cell in the body and which in turn fuels myriad physiological events such as muscle contraction, brain activity or tissue repair.

  Source Naturals offers a full line of vitamins in bioactive forms, allowing you to tailor a nutritional supplementation plan to your individual needs.

  VITAMIN A and CAROTENOIDS

  Vitamin A

  Vitamin A is a generic term for a class of fat-soluble substances called retinoids, which can either be consumed preformed or synthesized by the liver from plant pigments called carotenoids (see 'Carotenoids', below). An essential nutrient, vitamin A is perhaps best known for its role in vision.

  The outer segments of the rods, a type of light-sensitive cell in the retina of the eye, contain a pigment called rhodopsin (or 'visual purple') that mediates vision in dim light. Cone cells mediate color vision via three additional pigments. Both rods and cones are surrounded by pigmented epithelial cells that store vitamin A. Rhodopsin is formed from a protein called opsin and a vitamin A-dependent compound called 11-cis retinal. As light strikes the rods and cones it is absorbed by the pigment molecules, and retinal is split off from opsin. This chemical change allows an electrical impulse to be sent to the optic nerve and thus to the brain. The pigment must then be regenerated from opsin and retinal. Repeated small losses of retinal during this process require a constant replenishment of vitamin A to the eyes.

  Vitamin A also plays an extremely important role in epithelial cell differentiation. Cell differentiation is the process by which a cell undergoes a change to a specialized cell type, allowing it to perform particular functions in the body. It is not yet understood precisely how vitamin A is involved in this process. One hypothesis is that it directly affects gene expression through its interaction with chromatin, a complex of DNA, RNA and protein in the cell nucleus. These interactions affect the process of transcription of DNA to messenger RNA, leading to synthesis of a specific group of cellular proteins.

  Each one of us carries in our DNA a unique genetic blueprint. This genetic material is the same in every cell of our bodies. It is only because of this mysterious and magical process of differentiation that we have specialized cell types - and therefore eyes, ears, lungs and hearts.

  Vitamin A is necessary, either directly or indirectly, for the healthy growth and functioning of many of our tissues and organ systems, including the eyes, the skin, the bones, the reproductive system, and the natural defenses. It is not yet known whether this requirement is due to the role of vitamin A in cell differentiation or whether there are other physiological processes for which vitamin A is essential.

  Carotenoids

  Vitamin A is related to a class of nutrients called carotenoids, including alpha and beta carotene, lycopene and lutein. Carotenoids are botanical pigments whose colors range from red to orange to yellow. Some carotenoids, particularly beta carotene, can be converted into vitamin A predominantly in the intestinal mucosa and to some extent in the liver. Carotenoids are completely non-toxic; their conversion into vitamin A is well-regulated by the body, making them extremely safe sources of this essential nutrient.

  In addition to their role as safe sources of vitamin A, carotenoids are powerful nutrients in their own right. Their primary claim to fame is their powerful antioxidant action, particularly against singlet oxygen. Singlet oxygen is an 'excited' ion of oxygen which, while not technically a free radical, is nonetheless highly reactive. It causes 'oxidative' reactions which can impair or destroy membranes, enzymes and DNA. It can also lead to the formation of free radicals which can cause additional damage.

  Certain carotenoids such as beta carotene, because of their chemical structure, can neutralize singlet oxygen by absorbing its extra energy and dissipating it throughout the carotenoid molecule, releasing the energy as heat and converting the singlet oxygen back to 'normal' oxygen. One molecule of beta carotene can quench up to 1000 molecules of singlet oxygen.

  In addition to their role as singlet oxygen quenchers, carotenes provide antioxidant protection against free radicals as well. In nature, they protect plants from photo-oxidative reactions; in humans, certain carotenoids, notably beta carotene, may help protect the skin from such reactions. Other carotenoids may provide more localized protection to particular organs. Lutein and zeaxanthin, for example, are selectively concentrated in the retina of the eye. Along with vitamins C and E, carotenes are among the most important nutrient antioxidants in the human body.

  
  
  --
  VitaNet ®
  VitaNEt ® Staff
  
  

  Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=250)

  ---

  Menopause Multiple - Eternal Woman
  

  Date: June 03, 2005 05:54 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Menopause Multiple - Eternal Woman
  

  Menopause

  Menopause happens to all women, but affects each woman uniquely. For some, the end of fertility (and the end of concerns about contraception) brings a sense of freedom. For others, it is a time of troublesome symptoms or perhaps the need for certain lifestyle adjustments. Menopause is a bridge to a point in life when many women report feeling more confident, empowered and energized than in their younger years. MENOPAUSE MULTIPLE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems: hormonal regulation, bone metabolism, cardiovascular health, energy generation and circulation.

  After menopause, the ovaries no longer secrete two critical steroid hormones in the amount or pattern characteristic of a regular menstrual cycle. These two hormones are estrogen and progesterone. The transition from regular ovarian function to its absence is often called the perimenopause or perimenopausal transition. The time involved can range from one to 10 years. More than one third of the women in the United States, about 36 million, have been through menopause. With a life expectancy of 81 years, a 50-year-old woman can expect to live more than one third of her life after menopause. Low estrogen levels are linked to some uncomfortable symptoms in many women. The most common and easy to recognize symptom is hot flashes -- sudden intense waves of heat and sweating. Some women find that these hot flashes disrupt their sleep, and others report mood changes. Other symptoms may include irregular periods, vaginal or urinary tract infections, urinary incontinence (leakage of urine or inability to control urine flow), and inflammation of the vagina. Because of the changes in the urinary tract and vagina, some women may have discomfort or pain during sexual intercourse. Many women also notice changes in their skin, digestive tract, and hair during menopause. Because the menopausal years place unique nutritional demands on a woman’s body, Source Naturals created MENOPAUSEMULTIPLE. This comprehensive formula brings together optimal amounts of the finest phytonutrients and herbs--including genistein, black cohosh, and chaste berry--plus vitamins and minerals known to support the biochemistry of mature women.

  Bio-Aligned Formula™

  MENOPAUSE MULTIPLE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with female hormone function.

  Hormonal Regulation

  Hot flashes are related to hormone levels. As estrogen declines, FSH and LH (folliclestimulating and luteinizing hormones) increase, causing blood capillaries to dilate. This brings more blood and higher temperatures to the skin. Soy isoflavones and other herbs can mimic the effects of estrogen. Support for the adrenal glands is important since they account for most estrogen production after menopause.

  Musculoskeletal System

  During and after menopause, a woman’s hormonal balance and biochemistry change. Lower estrogen levels may affect bone density. Phytonutrients and calcium are important to maintain healthy bones in postmenopausal women. Calcium and magnesium work together in the metabolism of bone.

  Heart & Circulation

  Menopause increases concern for the health of the heart and circulatory system. Soy isoflavones and other ingredients may help maintain healthy cholesterol levels. To regulate homocysteine levels for cardiovascular health, vitamins B-6, B-12, and folic acid are critical.

  Liver Support

  Among its many functions, the liver has the important job of promoting hormonal balance by processing excess levels of hormones. The powerful antioxidant, N-acetyl cysteine, helps the liver detoxify chemicals and milk thistle is a liver protectant.

  Energy Generation

  The fatigue that is common during menopause makes nutritional support for energy and metabolism especially important. Metabolism can influence weight, energy levels, and mood. MENOPAUSE MULTIPLE contains ingredients that support energy generation, including the advanced nutrients CoQ10 and lipoic acid and ginkgo biloba.

  Antioxidants: Anti-Aging

  Antioxidants help protect the circulatory system, which is important as estrogen declines. Antioxidants also defend tissues and cell membranes in all your body systems from free radicals, which are formed during normal cellular metabolism. Some important antioxidants: vitamin E, vitamin C, selenium, zinc, and manganese all have strong antioxidant powers.

  Lifestyle Tips for a Healthy Transition

  Get Moving. Exercise is a powerful remedy for many menopause complaints and may help prevent future menopause-related diseases. It promotes better, more restorative sleep, and it stimulates production of endorphins, or “feel good” brain chemistry. Some women report having fewer hot flashes when they exercise regularly. Eat Well. A balanced diet low in saturated fat and high in whole grains, fruits and vegetables, with adequate water, vitamins and minerals contributes to good health. Women at perimenopause and beyond have special dietary concerns, because both heart disease and osteoporosis are greatly affected by diet. A balanced diet is also important for bone development and maintaining bone strength. Some women – especially those who are elderly and have reduced appetites, who diet frequently, who don’t consume diary products, or who have eating disorders – may not consume adequate vitamins and minerals to maintain optimal bone mass. There is evidence that the natural, estrogenlike compounds in soybeans and many other plant foods used in MENOPAUSE MULTIPLE may reduce hot flashes and vaginal dryness and increase bone density in women after menopause. Studies suggest that body cells respond to plant estrogens as if they were weaker versions of the human hormone. So consuming more of these estrogen-mimicking compounds may help compensate for the loss of estrogen naturally as women age. Prevent Bone Loss. Osteoporosis is one of the most preventable of bone diseases. Exercise maintains the strength of bones through aerobics, stair climbing, hiking, or walking. Prevention focuses on nutrition for bones, including a sufficient calcium intake of 1000 to 1500 mg/day.

  Musculoskeletal System: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Boron, Calcium, Magnesium, Manganese, Vitamins A, B-6, B-12, C, D & E, Folic Acid

  Heart and Circulation: Black Cohosh, Coenzyme Q10, Dong Quai, Licorice, Soy Isoflavones, Magnesium, Vitamins B-6, B-12, & E, Folic Acid

  Hormonal Regulation: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Vitex, Vitamins B-5 & C

  Liver Support: Coenzyme Q10, N-Acetyl Cysteine, Dandelion, alpha-Lipoic Acid, Silymarin, Selenium, Vitamin C, Biotin

  Antioxidant Defense: Coenzyme Q10, N-Acetyl Cysteine, alpha-Lipoic Acid, Silymarin, Selenium, Zinc, Vitamins A, C & E

  Energy Generation: alpha-Lipoic Acid, Coenzyme Q10, Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-5, & B-6, Niacinamide

  References
  Abraham, G.E. & Grewal, H.G. 1990. JRM, 35:503. Anderson, J.W., et al. 1995. The New England Journal of Medicine, 335(5): 276-82. Avioli, L. V. (1993). Calcium and Bone: Myths, Facts and Controversies in the Osteoporotic Syndrome: Detection, Prevention and Treatment, 3rd ed. (Avioli ed.) New York: Wiley-Liss. Christy, C.J. 1945. American Journal of Obstetrics & Gynecology, 50:45. Colborn, Theo. 1996. Our Stolen Future. New York: Dutton. Murkies, A.L., et al. 1995. Maturitas, 21:189-95. Nielsen, F.H., et al. 1987. FASEB J, 1:394-97. Raines, E.W., & Ross, R. 1995. Journal of Nutrition, 125:624S-30S. Tranquilli, A., et al. 1994. Gynecological Endocrinology, 8(1):55-8.

  
  
  --
  VitaNet ®
  VitaNet ® Staff
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=173)

  ---

  Life Minerals - Why are Minerals So Important?
  

  Date: June 02, 2005 01:14 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Life Minerals - Why are Minerals So Important?
  

  Why Are Minerals So Important?

  The value of adequate mineral intake for overall health cannot be overstated. Their effects are vast and broad; their deficiencies devastating. Minerals are components of body tissues and fluids that work in combination with enzymes, hormones, vitamins and transport substances. Minerals participate in nerve transmission, muscle contraction, cell permeability, tissue structure, blood formation, acid-base balance, fluid regulation, blood pressure control, protein metabolism and energy production. The human body requires large amounts of some minerals, and trace amounts of others, while some minerals – such as Lead, Mercury and Aluminum – are toxic to the body. Those minerals that are essential to health in relatively high amounts – Calcium, Phosphorus, Potassium, Sulphur, Sodium, Chlorine, and Magnesium – are called macrominerals. Trace minerals – Zinc, Manganese, Copper, Iron, Chromium, Selenium, Iodine and Molybdenum, to name a few – are those which are present in the body in minute amounts, but are just as essential to health as the major minerals. One of the main functions of minerals in the body is to activate enzymes. Magnesium, for example, activates over 300 different enzymes, while Zinc “turns on” over 100. Enzymes are catalysts, functioning in the cells to accelerate chemical reactions. All of these chemical reactions collectively are referred to as “metabolism”, which is the very basis of life.

  Why Do We Need Minerals Now More Than Ever?

  
  I. The Decreasing Levels of Minerals in Today’s Foods Unlike the compost fertilizers of the past, today’s “high-tech” fertilizers do not replace many of the nutrients essential to both the natural growth of crop plants and to human beings, who depend on them for adequate nutrition. As a result, even a “good” diet may provide less nutrition than is generally required. In addition, many modern food additives bind minerals so tightly in food that they can no longer be absorbed or utilized by the body. A moderate intake of one such additive, EDTA (estimated American daily intake is 50-100 mg), was found in a scientific study to reduce iron absorption by 50%! Dietary studies have shown that mineral deficiencies are so prevalent, it’s rare that anyone gets even the minimum RDA levels of them all. The following are examples of the unfortunate findings:

• • A study by the USDA in the mid-1980s on Chromium status in adults found that NONE of the people tested consumed even the lower level of the Chromium “Safe & Adequate Intake” range of 50 to 200 mcg.
• • It is estimated that up to 90% of all Americans may be Magnesium-deficient, even by RDA standards (considered by many Magnesium experts to be already too low).
• • A study published in the prestigious American Journal of Clinical Nutrition in the late 1970s found 70% of Americans getting less than the 15 mg RDA for Zinc, with most getting only 8- 11 mg per day.
• • Among Americans who do not eat a high-dairy diet or take Calcium supplements/antacids regularly, virtually no one will achieve the current 1000 mg per day RDA for Calcium.
• • According to nutritionists, women not taking Iron supplements would need to consume a 3000 calorie diet daily(!) to regularly achieve the U.S.RDA for Iron of 18 mg. Yet most women, especially those who are weight-conscious, consume less than 2000 calories a day, many as little as 1200-1500 calories!

  
  II. The Increasing Need for Minerals in Today’s Environment and Lifestyle Various aspects of the modern environment and lifestyle — some of which are discussed here — severely affect mineral nutrition in the body.

• • The results of studies conducted in Michigan and Maryland medical facilities show that physical and psychological stress in healthy adults produces acute deficiencies of trace minerals despite otherwise adequate dietary intake. Given the fact that many adults in America are not healthy by medical standards, the loss of minerals with stress is possibly even greater than has been measured.
• • In addition, many of the prescription drugs that Americans commonly take chelate, or bind, with one or more minerals, making those minerals unavailable to the body. For example, diuretics flush Potassium out of the body and deplete Magnesium, and sedatives can lower blood levels of Calcium and Magnesium.
• • Heavy metal toxicity is also a major problem in modern America. Cadmium, Mercury and Lead, for example, are cumulative poisons, toxic even in low doses, and are increasingly prevalent in our environment because of their industrial uses. In the 1960s alone, over 200 million pounds of lead per year were released into the environment from the use of leaded gasoline. Data, published in 1987, indicates that people who have a good supply of the minerals Calcium, Zinc, Iron, Selenium, Copper, Chromium, and Manganese in their diets are largely protected against heavy metal poisoning. Conversely, if these minerals are deficient in the diet, there is a much greater danger of heavy metal toxicity.
• • Poor diet, cigarettes, alcohol, drugs, and the heating and spoiling of polyunsaturated fats all deplete mineral levels and produce damaging free radicals in the body. Minerals such as Selenium, Iron, Copper and Manganese, and Vitamins, such as C, work in the body to neutralize free radicals and thus diminish their harmful effects.

  What Is The Krebs’ Cycle? And What Are “Krebs’ Cycle Minerals”?

  The Krebs’ Cycle is the energetic root of life, taking place in every cell of the body. It produces 90% of the body’s total energy in the form of ATP. Krebs’ Cycle Minerals are those which are bound to the organic acids used in the Krebs’ Cycle. Such mineral complexes are increasingly becoming the standard in mineralinclusive supplements because they’re so good at what they do: Transport. They are especially effective at penetrating various cell membranes and organelle membranes, thus carrying their mineral partners inside the cell. Many of these organelles have membranes to keep out biochemical invaders; therefore, not just any substance can penetrate cells and their organelles.

  Source Naturals’ Life Minerals™: Optimal Mineral Supplementation

  All this technical and scientific information has been brought together by the experts at Source Naturals into one comprehensive multi-mineral formula: Life Minerals™. Many of the minerals in Life Minerals™ — Calcium, Magnesium, Potassium, Manganese and Iron — are bound to some of the best known transport agents in the body, the Krebs’ Cycle organic compounds. In addition, there are minerals not usually found in other mineral supplements, such as Silicon, Boron, Copper, and Molybdenum. Plus there are the Vitamins B6, C and D3, which have been shown to significantly enhance mineral absorption and utilization. In addition to the Krebs’ Cycle minerals, Life Minerals™ also uses superior forms of other minerals. The Zinc is OptiZinc™ Zinc Monomethionine, shown in scientific studies to be highly bioavailable, offering increased absorption. The Chromium is ChromeMate®, the non-yeast Glucose Tolerance Factor Chromium, believed by many to be the most superior form of Chromium. Copper Sebacate, a more bioavailable form of Copper, is also included. Minerals are crucial to both the structure and function of the body in hundreds of ways. But what good are mineral supplements if your body cannot utilize them to their fullest advantage? Supplementing your diet with Life Minerals™ is an important aid against deficiencies that may be more significant than suspected. By providing minerals with the highest bioavailability, and including significant potencies of each, Source Naturals’ Life Minerals is your best chance of reaping all the benefits that minerals have to offer.

  
  
  --
  VitaNet ®
  VitaNet ®
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=162)

  ---

  Genistein 1000mg Eternal Woman - Soy Supplement ...
  

  Date: June 02, 2005 10:30 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Genistein 1000mg Eternal Woman - Soy Supplement ...
  

  Genistein - Eternal Woman

  For most of human history, we existed in a world that was very different from the one today. Our endocrine systems evolved in an environment without synthetic chemicals. Unfortunately, today we’re surrounded by artificial hormone-mimicking compounds that disrupt the subtle biological processes that determine growth and reproduction. Receptors on our cells meant to receive natural bodily hormones can also accept molecules other than the ones they were intended to receive, placing our endocrine systems under considerable duress. Fortunately, certain plants contain estrogen-like compounds that are also accepted by hormone receptors in the human body – but with beneficial effects. Soybeans, which contain the isoflavone Genistein, can help regulate and maintain normal menstrual cycles and menopausal transitions. Source Naturals GENISTEIN is a concentrated form of the essence of the soybean.

  The Secret of Soy

  Not surprisingly, it was Ben Franklin who first introduced America to soybeans. Always on the lookout for beneficial imports, he was intrigued by the soybean cheese he saw in England. Today, tofu and other soy products are gaining popularity here in the West, in good part due to the reported benefits to populations that consume a considerable amount of soy products.

  Some researchers have postulated that the high intake of soy foods by Asians may be a key factor in their low incidence of certain health problems that are common in the West. For example, epidemiological studies show that women in Asia have a higher occurrence of normal trouble-free menopause. There is no Japanese word for hot flashes. Soy foods contain high concentrations of phytonutrients including phytosterols and isoflavones. Isoflavones are an important class of bioflavonoids whose properties have been well researched. Of the seven isoflavones contained in soybeans, the most active are genistein and daidzein. Source Naturals GENISTEIN contains over 11 mg of genistein, 42 mg of daidzein, and 86 mg of total isoflavones per four 1000 mg tablets.

  Genistein and Estrogen

  The subject of scientific studies since 1966, genistein research has been published in many journals including the American Journal of Clinical Nutrition and the Annals of the New York Academy of Science. Genistein has been shown to bind to the same receptor sites as estrogen. This helps to maintain normal menstrual cycles and menopausal transitions. By competing for human estrogen receptors, genistein causes excess estrogen to be sent to the liver for elimination. Conversely, when there is too little estrogen (the situation during menopause), phytoestrogens – genistein and daidzein – substitute for the lack of human estrogen, mitigating the effects of its absence.

  Genistein and Cell Growth

  One of genistein’s most promising functions is its ability to inhibit capillary proliferation. By neutralizing a growth factor called vascular endothelial (vegF), genistein protects cells. Genistein also shows pronounced inhibition of tyrosine kinase, the enzyme that interferes with normal cell growth. Soybeans are the only significant dietary source of genistein; however, the amount of soy foods necessary to meet the body’s needs can be difficult to incorporate into today’s diet. In Asia, the daily intake can be up to 20 times that of a Western diet. Source Naturals GENISTEIN is made from the germ of isoflavone-rich soybeans, using a chemical- free process that yields a consistent standardized isoflavone content. It requires approximately 400 pounds of soybeans to yield just one pound of finished product. With GENISTEIN, Source Naturals brings the remarkable properties of a time-honored food plant into your wellness program today.

  References
  

• • Colborn, Theo. Our Stolen Future. New York: Dutton, 1996.
• • Fotsis, T., et al. (1995). Journal of Nutrition, Vol. 125, 790S-797S.
• • Messina, M. & Messina, V., (1994). The Simple Soybean and Your Health. New York: Avery Publishing Group.
• • Molteni, A., et al. (1995). The Journal of Nutrition, Vol. 125, 751S-756S.
• • Persky, V. & Van Horn, L. (1995). Journal of Nutrition, Vol. 125, 709S-712S.

  
  
  --
  VitaNet ®
  VitaNet ® Staff
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=149)

  ---

  Tonalin CLA and Diet Tonalin CLA - May Help Loose Weight ...
  

  Date: June 01, 2005 12:45 PM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: Tonalin CLA and Diet Tonalin CLA - May Help Loose Weight ...
  

  Tonalin CLA and Diet Tonalin CLA

  Dramatic new research has identified a fatty acid that may positively influence body composition. Conjugated Linoleic Acid (CLA), found mainly in meat and dairy products, used to be abundant in our diets. But with the trend to lower fat diets, our CLA intake also is declining. It is an irony that so many Americans seem to be getting fatter, even as we eat less fatty foods. Researchers at the University of Wisconsin may have found an explanation for this paradox. Their studies suggest CLA may be an important nutrient for optimal body composition, possibly helping to reduce body fat and increase muscle. Aware consumers are unlikely to go back to the unhealthy, meat-laden diets of the past. But today CLA is available from pure sunflower oil. Introducing: Source Naturals TONALIN CLA.

  Research Uncovers an Unrecognized Fatty Acid

  CLA is a term referring to a group of derivatives of the essential fatty acid, linoleic acid. CLA, a polyunsaturated fatty acid, is found naturally in certain foods, especially meat and dairy products. CLA has been known for more than 18 years, but studies of its relationship to body composition are more recent. Studies now suggest that CLA may positively influence our bodies’ efficiency in using food, and have a beneficial effect on the balance between fat and muscle in our bodies. Clinical trials are now underway to explore the mechanism by which CLA works, and to determine whether the results of these laboratory and animal tests are also applicable to humans.

  Additional Benefits

  CLA may have a number of other benefits for our bodily systems. In fact, the University of Wisconsin researchers first discovered CLA’s role in influencing body composition as a result of research they were carrying out on CLA’s other properties. Among other important functions, CLA may be beneficial for our cardiovascular system due to its role in helping maintain normal cholesterol levels.

  CLA: Insufficient in Today’s Diet

  CLA used to be abundant in our diets. Today, however, Americans are eating less beef and full-fat dairy products. This translates to lower levels of CLA in our diets. CLA content is also much lower than it used to be in beef. Researchers believe this may be related to changes in the way cattle are fed. The green grass eaten by grazing cows is rich in polyunsaturated fatty acids including linoleic acid. Cows have a unique digestive system that converts linoleic acid to CLA - a close chemical relative of linoleic acid. The CLA is then stored in the cows’ tissues. It is possible that, since cattle today are predominantly fed oats, barley and hay rather than grazing on grass, they are no longer producing as much CLA.

  A Plant-Based Alternative

  Now, with Source Naturals TONALIN™ CLA, you can derive the benefits of CLA without consuming large amounts of animal fat. TONALIN CLA is manufactured by a proprietary process from sunflower oil. Source Naturals TONALIN CLA is available in 1000 mg softgels, consisting of 600 mg of CLA standardized to contain 40% cis-9-trans-11-octadecadienoic acid, one of CLA’s most important constituents. Three softgels - the suggested daily use - provide approximately the same amount of CLA as eating five pounds of beef, or 45 one-ounce slices of processed American cheese, or almost a gallon of ice cream every day! Source Naturals TONALIN™ CLA is available in 30, 60 and 120-capsule bottles.

  References
  Belury, Martha A. & Vanden Heuvel, John P. (1997). Nutrition & Disease Update Journal: 1(2) (in press). Chin, S. F. et al. (1992). Journal of Food Composition and Analysis:5. 185-97. Pariza, M. et al. (1996). Abstract of Speech at Environmental Biology ‘96, Food Research Institute, University of Wisconsin: Madison. Parodi, P.W. (1994). Australian Journal of Dairy Technology. Dairy Research and Development Corporation: Victoria. Conjugated Linoleic Acid is licensed under U.S. patents: 5,428,072; 5,430,066; and 5,554,646. Tonalin™ is a trademark of Pharmanutrients USA.

  
  
  --
  VitaNet ®
  VitaNet ® Staff
  
  

  (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=141)

  ---

  CAT’S CLAW - Herbal Protection from the Amazon ...
  

  Date: June 01, 2005 09:45 AM
  Author: Darrell Miller (dm@vitanetonline.com)
  Subject: CAT’S CLAW - Herbal Protection from the Amazon ...
  

  Cat's Claw

  Another health secret of the Amazon rainforests is now being revealed in an exciting new product from Source Naturals called CAT’S CLAW or Uncaria tomentosa. Like Pau D’ Arco before it, the herb Cat’s Claw has been used in traditional Peruvian herbalism for hundreds of years, but it is only now getting the attention it deserves in the United States.

  Source Naturals® Cat’s Claw – An Amazonian Treasure for the Western World

  This unique herb is actually a high-climbing vine found in the highlands of the Peruvian Amazon. It is named for its claw-like thorns that resemble a cat’s claw. The bark from the Uncaria tomentosa vine is harvested for two important reasons: first, many of the highly active components are found in the bark; and second, the bark can be harvested without needless destruction of the vine, thereby protecting the delicate Amazon ecosystem.

  The biologically active constituents in Source Naturals CAT’S CLAW have uniquely protective properties. Researchers have discovered that components extracted from the herb can enhance the body’s natural defenses, help to keep the system balanced in the face of environmental stressors, and can support intestinal health.

  Ongoing studies are being performed to determine the exact constituents in the vine which are responsible for these activities. Oxindole alkaloids, a group of compounds that strongly affect human physiology, have been identified in some of the vine extracts. Researchers have also isolated compounds, called quinovic acid glycosides, that seem to have high free radical scavenging potential. In addition, polyphenols, triterpenes and plant steroids have been isolated from herb extracts.

  campesterol, stigmasterol, and Betasitosterol hold the most promise. Betasitosterol is a white, waxy substance that has been extensively studied because of its close resemblance in structure and properties to cholesterol, and for its powerful shielding potential. Betasitosterol so closely resembles cholesterol that it binds the cholesterol absorptive sites and prevents cholesterol absorption. The presence of these additional compounds may further explain the herb’s protective and rejuvenating characteristics. While research unravels the multi-faceted properties of this unique Amazonian herb, the intrinsic benefits can be enjoyed by all who choose to be proactive in their quest for optimal health.

  Reference:
  

• • Aquino et al. J. of Nat. Prod. 52: 679-685, 1989.
• • Aquino et al. J. of Nat. Prod. 53: 559-564, 1990.
• • Cerri et al. J. of Nat. Prod. 51: 257-261, 1988.
• • Montenegro de Matta et al. Il Farmaco Ed. Sc. 51: 527-535, 1975.
• • Stuppner et al. Chromatographia. 34: 597-600, 1992.
  
• The above information has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.



--
VitaNet ®
VitaNet ® Staff



(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=129)

---

Important Information for Allergy Sufferers


Date: May 13, 2005 09:52 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Important Information for Allergy Sufferers


Important Information for Allergy Sufferers

Richard Conant, L.Ac. C.N.

Imagine you are one among millions who greet each spring with worry about the flood of pollen that fills the air this time of year. When the pollen season arrives, as it inevitably does, you find yourself with two choices. You can either take over-the-counter antihistamines and put up with unpleasant side-effects, or endure the sneezing, runny nose, itchy, watery eyes and other discomforts of hay fever.

If there was a natural ingredient, a nutritional substance found throughout nature in many foods and plants, that could offer an alternative, would you not be interested?

Quercetin, one among hundreds of flavonoids found throughout the plant kingdom, is this ingredient. Quercetin has been researched in numerous pharmacological studies. The results of this work strongly suggest that quercetin helps to stabilize the fundamental process in the body which causes an allergic reaction. Quercetin, as shown in test-tube ("in vitro") studies, prevents the release of histamine from "mast cells," immune cells that stand guard in the tissues which meet the outside environment—the nasal passages, the lungs, the digestive tract and skin. While this has yet to be confirmed by human clinical trials, in the picture that emerges from the research so far, quercetin looks like a rescue nutrient for allergy sufferers.

Reports from Quercetin Users

I have seen numerous reports from individuals who have indeed achieved significant reductions in allergic sensitivity by using quercetin. And this includes food allergies as well as environmental allergies. Anecdotal stories like these carry little weight among scientists, because they do not provide evidence that the observed result will be repeated in other cases. Only placebo-controlled, double-blind studies can produce this kind of scientific proof. Yet, when anectodal evidence (this includes physician "case reports") correlates with the results of pharmacological research such as we have on quercetin, I believe it should be taken seriously. And quercetin is a nutrient that works effectively when taken as a dietary supplement.

For example, one gentleman writes that his wife, who is allergic to pollen and dust, is now "sneeze-free" after using quercetin for three years. A Pennsylvania woman writes that her husband, also a long time allergy sufferer, "seems to be nearly allergy free" after one month of use. Another man says that "quercetin has literally changed my life." These are not isolated cases; a respected nutritionist who specializes in allergies and environmental problems has seen many similar outcomes with a quercetin. Clearly something significant is going on with respect to quercetin as a nutritional approach for overcoming allergies.

Bear in mind, though, that quercetin does not function like an antihistamine medication; it is not a quick fix. As a nutrient that helps to normalize body functions naturally, quercetin needs time to work, and should be taken for at least two or three weeks to achieve these results.

Quercetin Quiets the Allergic Response

Exerting a broad range of biological effects, quercetin is perhaps the most active and versatile flavonoid. In test-tube studies, quercetin acts directly on the mast cell in a way that quiets the allergic response.

An allergic reaction occurs when IgE antibodies, positioned on the mast cell surface, come in contact with a potential allergy-causing substance like pollen. The mast cell is then signaled to release histamine from storage granules located inside the cell, through a process called "degranulation." The histamine circulates throughout the body, causing the runny nose, itching and other discomforts associated with allergies.

Quercetin stabilizes mast cell membranes, in effect turning down the allergic response signal. Quercetin also slows other mechanisms which are involved with inflammation, such as the production of inflammatory prostaglandins and leukotrienes. This adds to its membrane-stabilizing effect, and its value in allergy control.

Quercetin appears to substantially raise the threshold for initiation of an allergic reaction. In allergy sufferers this threshold is low, for reasons which are not well understood. They may have more IgE antibodies than normal, making the mast cells overly "trigger happy." Histamine has its proper place in the immune response that defends us against truly harmful foreign substances in the body. But like many chemicals produced by the body, histamine is a two-edged sword. In allergy-prone individuals, the mast cells have become overreactive, releasing too much histamine, unnecessarily. With quercetin in the bloodstream, histamine release from mast cells is kept under control. Quercetin's ability to down-regulate both the inflammatory and allergic responses makes it, I believe, a highly important nutrient for humans to consume on a regular basis.

Quercetin-the Scientific Evidence

Several studies, published in respected journals such as the Journal of Allergy and Clinical Immunology and others, have demonstrated quercetin's ability to control the release of histamine from mast cells. (Quercetin has the same effect on basophils, a type of white blood cell that also contains histamine.) In these experiments, mast cells taken from both animals and humans are exposed in the test tube to various substances—called "antigens"— that stimulate histamine release. The researchers then add an inhibiting agent such as quercetin to the mixture and measure the differences in histamine output. Quercetin has shown itself to be one of the more powerful histamine inhibitors, more powerful, in fact, than disodium cromoglycate, an anti-asthma drug.

Quercetin has other beneficial properties. A strong antioxidant, Quercetin has a higher level of antioxidant activity than both vitamin C and vitamin E. (Quercetin enhances the antioxidant activity of vitamin C; quercetin and vitamin C are true synergists.) Quercetin has been shown to block the oxidation of LDL cholesterol by free radicals. Quercetin also protects cell membranes from being injured by oxidized LDL. The damage that oxidized LDL causes to the delicate membranes of blood vessel linings allows plaque deposits to form, setting the stage for atheroslcerosis. These observations point to quercetin as a key nutrient for maintaining cardiovascular health.

Like all flavonoids, quercetin is not classified as an essential nutrient, although flavonoids were once called "Vitamin P." In view of its many beneficial actions, quercetin is a nutrient that clearly has important roles to play in human nutrition, for allergy sufferers, and for everyone.


• Activated Quercetin from Source naturals 50tbs
• Activated Quercetin from Source Naturals 100tbs
• Activated Quercetin from Source Naturals 100 caps
• Activated Quercetin from Source naturals 200 caps
• Quercetin Bromelain and Vitamin C from Solaray 60caps
• Quercetin Bromelain and Vitamin C from Solaray 120caps
• Quercetin 1000mg 60ct from Kal
• Quercetin 500mg 90ct from Solaray
• Quercetin Nutra Drops 4 fl.oz.
• Quercetin with Bromelain and Ester C 60ct from KAL
• Quercetin and Bromelain complex from Doctors Best 180ct (Best Value)
• Quercetin 400mg 100ct Natures Life


--
VitaNet ®
VitaNet ® Staff


(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=47)

---

Delivers 1000 IU vitamin D


Date: May 10, 2005 04:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Delivers 1000 IU vitamin D


Delivers 1000IU Vitamin D

100% Vegetarian, high potency Vitamin D is vegetable cellulose capsules.

Vitamin D has been extensively studied for it's positive effects on bone health. It has been shown to effecively help promote the absorption and utilization of calcium and phosphorus by the body to enhance bone mineralization.

Although Vitamin D can be made in the skin from the provitamin 7-dehydrocholesterol, it requires sunlight to become activated. During the winter months, many people may not receive enough sunlight to convert vitamin D to its active form. Taking 1000 IU of Vitamin D can help maintain Vitamin D stores in the body.

• 1 convenient vegetarian capsule provides 1000 IU vitamin D as Ergocalciferol D-2.
• Dry, water-dispersable form for individuals with difficulty digesting fats or for those on fat-restricted diets.
• 100% Vegetarian Formyla




Vitamin Dry D 1000IU 60 vegicaps




--
VitaNet®
VitaNet® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=24)

---

Red Yeast Rice can Lower Cholesterol. Scientific Studies prooven


Date: May 09, 2005 11:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Red Yeast Rice can Lower Cholesterol. Scientific Studies prooven


Department of Biochemical Pharmacology, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100083, China.

Long-term effects of Cholestin (Monascus purpureus rice; red yeast rice) on serum lipids and severity of atherosclerosis were examined in rabbits fed for 200 days on a semi-purified diet containing 0.25% cholesterol. Serum total cholesterol was 25 and 40% lower, respectively, in rabbits fed 0.4 or 1.35 g/kg/day of Cholestin (Monascus purpureus rice; red yeast rice) compared to controls. This treatment also lowered serum LDL cholesterol. This 200-day treatment significantly reduced serum triglycerides and atherosclerotic index (ratio of non-HDL-cholesterol to HDL-cholesterol). Although similar reductions of total, LDL-cholesterol and triglycerides were observed, a parallel group of rabbits fed lovastatin (0.0024 g/kg/day) failed to reduce the index significantly. Apolipoprotein A(1) was increased and apolipoprotein B was reduced in all treatment groups. Severity of atherosclerosis was reduced significantly in all treatment groups. The sudanophilic area of involvement was 80.6% in controls, and reduced significantly; to 30.1% on the low dose (Monascus purpureus rice; red yeast rice), and 17.2% on the high dose. Lovastatin reduced severity of lesions by 89% (sudanophilia) and 84% (visual). Visual grading of lesion severity showed reduction by 38% and 68%.

PMID: 12873712 [PubMed - indexed for MEDLINE]

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=14)