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Curcumin and Grapeseed
September 01, 2020 11:03 AM
Smoking, Chemical exposure, pesticides, nutrient deficiencies, to much sun exposure, and over the counter drugs and prescriptions can cause cancer. In the news, there are forever chemical roundup found in our water supply, it is no wonder we are laden with cancer as a society.
Fortunately, a healthy cancer preventing diet along with natural plant compounds can be far more effective and cost a lot less than conventional care alone.
Two top suggested natural medicines available right now are curcumin and grape seed extract. These two herbs are an amazing pair, curcumin is a fat soluble herb to fight oxidation on the fatty oil side in the body and grape seed extract is water soluble, making it a great antioxidant to fight oxidative stress on the water side of a cell. Cells in the body are made up of oil(fats) and water. The impact of both together on your health is virtually miraculous.
Curcumin neutralizes unstable free radicals that take electrons from nearby molecules, and stop them from creating a cascade of damaged cells. It also reduces inflammation reduces inflammation markers in the body to prevent prevent tissue degradation.
Curcumin has been shown to stop the changes that happen from free radical damage causing normal cells to become cancerous, and tumorous formations, and can even stop cancer from metastasizing or migrating to other parts of the body. Published studies anticancer activity have found that it can suppress breast, prostate, liver, skin, colon and lung cancer cells.
Curcumin Must Be Absorbed To Be Useful
One of the challenges or using curcumin for cancer prevention and treatment is that not all curcumin extracts are easily absorbable into the body. Blending curcumin in Turmeric essential oil enhances absorption and provides the additional benefits of ar-turmerone, a compound in the oil.
Curcumin Makes Chemo More Effective
There is big potential for curcumin when used with conventional treatment. BCM-95 curcumin, through research, has shown to sensitize human colon cancer cells to chemotherapy treatment where it would otherwise be resistant to this form of treatment. In some cases tumor recurrence rates can be as high as 60% but when treated with curcumin while under conventional treatment, curcumin boosted the effectiveness of the chemo drug 5-fluorouracil against cancer stem cells.
Curcumin has great potential in conjunction with conventional cancer treatment and recovery. It has been found that as chemo treatment progresses, cancer cells become resistant to the chemo treatment and the dosage has to be increased as the treatment continues increasing the toxic side effects. Fortunately, curcumin taken in conjunction with conventional cancer treatment can improve the effectiveness of chemo and so the dosage can be lowered reducing the toxic side effects for individuals. This is good news!
Curcumin Protects The Body During Cancer Treatment
In a clinical study with curcumin, it showed to alleviate side effects of one of the most common treatments of prostate cancer known as external beam radiotherapy (EBRT) where the doctor uses radiation to destroy tumorous cancel cells. This sort of therapy has many side effects making it a difficult therapy for most men. I often causes sexual dysfunction, digestive problems, urinary tract pain and loss of control. The higher the radiation dosage the more effective the treatment is but this causes significant discomfort, that is why most doctors lean towards lower dosages which makes the treatment less effective.
The clinical study administered 3000mg of BCM-95 curcumin that is 1000mg x 3 per day or a placebo one week before therapy started and during the treatment length. Each capsule of curcumin contained curcuminoids, curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oil of turmeric, this is a full spectrum curcumin supplement.
At the end of the treatment which lasted 20 weeks the most Dramatic difference between the two groups in the study was urinary symptoms. The curcumin group said a 50% decrease in symptoms or side effects of the radiation. Also, researchers noted that the curcumin did not reduce the efficacy of the EBRT.
May 23, 2019 03:50 PM
Mood and emotional health can Dramatically impact quality of life. Through the years, I have met many people who are looking for a healthy way to support peace of mind, a sense of happiness, or emotional balance in their lives.* When I learned about the ways standardized saffron can boost mood, I decided to combine it with BCM-95 curcumin, which has 4 published human studies demonstrating significant support for mood and emotional balance. The unique combination of these two ingredients provides elevated levels of benefits that are unmatched by either herb alone. You too can truly feel the difference this product can make!*
The Powerful, clinical strength botanicals in Saffron Lift provides outstanding mood support!*
Not only will Saffron Life effectively life mood, it will also promote overall health and well-being in those that consume it regularly.
Common vitamins linked to a lower risk of pancreatic cancer
May 07, 2019 04:31 PM
While pancreatic cancer is a terribly dangerous disease, a vitamin supplement regime may be able to mitigate some of the risk of developing it. A Chinese study that looked at health data from over 1.2 million people discovered a clear correlation between higher intake of vitamins and lower risk of pancreatic cancer. Specifically, the researchers believe that the vitamins, through a variety of different mechanisms, induce apoptosis in cancer cells. This demonstrates that a healthy diet combined with supplements can greatly reduce your cancer risk.
"Fortunately, there are lifestyle changes that can dramatically reduce the risk of falling victim to pancreatic cancer, including a vitamin (and mineral) regimen."
Read more: https://www.naturalhealth365.com/pancreatic-cancer-vitamin-2775.html
GREAT news: Cannabis found to reduce diabetic neuropathy pain
April 13, 2019 11:16 AM
Scientists from the University of California, San Diego have performed new research indicating that cannabis/marijuana may be highly effective at relieving the pain caused by diabetic neuropathy. The research found that cannabis compounds are an excellent match for the cannabinoid receptors found throughout the human nervous system, and on inflammatory cells. Patients who received cannabis vapors or cannabis smoke in the study reported drastically reduced pain from their neuropathy. More research is needed to fully explore these effects, to include wider use of placebos and a wider range of different dosage arrangements.
"A team of researchers from the University of California, San Diego deserves the credit for finding that cannabis has an amazing ability to greatly reduce, and in some cases completely eliminate, diabetic neuropathy pain – and all without the need for dangerous and typically ineffective pharmaceutical drugs."
Read more: https://www.naturalnews.com/2019-02-13-cannabis-found-to-reduce-diabetic-neuropathy-pain.html
Easily boost your immune system by eating more pomegranates, studyconcludes
March 27, 2019 10:34 AM
Pomegranates have long been recognized for their beautiful red seeds that present in a much more vibrant light than many other fruits. Now researchers are finding that pomegranates have several health benefits, especially when it comes to treating chronic inflammatory conditions. A study performed on mice showed that the inflammation biomarkers present within their systems were dramatically reduced when they were given pomegranate extract on a continual basis, showing that it could have a similar impact on humans.
"Scientists from King Saud University concluded that pomegranates can boost the immune system and treat diseases such as malaria."
Read more: https://www.naturalnews.com/2019-01-27-easily-boost-your-immune-system-with-pomegranates.html
Following a fiber-rich diet has a positive effect on chronicinflammatory joint diseases
February 19, 2019 07:53 AM
A diet that is high in levels of fiber as well as short-chain fatty acids can improve many areas of your physical health. For those looking to lose weight, diets high in fiber helps you fill up faster, and it also helps you stay fuller for longer periods of time. This naturally leads to a reduction in body mass. Over 22 studies have also documented how these high-fiber diets can promote heart health by reducing cardiovascular risk by nine percent.
"A study published in Nature Communications revealed following a fiber-rich diet has a positive effect on chronic inflammatory joint diseases like arthritis, resulting in stronger bones."
Read more: https://www.naturalnews.com/2019-01-14-fiber-rich-diet-for-chronic-inflammatory-joint-diseases.html
The Arjun tree holds potential for lowering blood sugar andcholesterol levels
January 08, 2019 09:58 AM
According to the Journal of Ayurveda and Integrative Medicine, Arjun Tree extract may have benefits for moderating your blood sugar and also your cholesterol levels. Diabetics are at dramatically higher risk of dying from heart conditions, perhaps because hyperglycemia tends to raise blood pressure and damage the circulatory system. The study in question focused on Wistar rats that received a high-fat diet, and found that Arjun Tree extract improved insulin sensitivity and liver triglycerides, and exhibited a pronounced anti inflammatory effect.
"In this study, which was published in the Journal of Ayurveda and Integrative Medicine, the researchers were able to determine that Arjun tree extracts exhibit anti-hyperglycemic and anti-hyperlipidemic activity."
Read more: https://www.naturalnews.com/2018-12-24-arjun-tree-lowers-blood-sugar-and-cholesterol-levels.html
Eat more bitter melon to improve your health
October 26, 2018 08:51 AM
If you are looking to improve your healthy dramatically, you must begin to understand the role that a diet can play in that. You want to be healthy, then the chances are that you need to cut out some foods that you like. If you are eating too much sugar, that is bad for you. Too many carbs, that is not good for you either. If you are to eat bitter melon on a consistent basis, your health will improve.
"Research has revealed that bitter melon (Momordica charantia) a vine that produces a strange-looking fruit with an even stranger flavor, may help treat cancer and inflammation."
Read more: https://www.naturalnews.com/2018-10-23-eat-more-bitter-melon-to-improve-your-health.html
Why your brain fails as you age, what you can do now
August 24, 2018 09:53 AM
It is the mitochondria inside your organelles that produce adenosine triphosphate, and if it does not function now then that is bad news for you. It means that your risk of developing a degenerative disease rises dramatically. No organ in your body is more dependent on energy than your brain, and older people who have their energy impaired open themselves up to such diseases. Additionally, as one ages, their mitochondria is decreased in functions and numbers.
"If your mitochondria are not functioning well, your risk for chronic degenerative diseases will radically increase."
Read more: https://www.healthnutnews.com/why-your-brain-fails-as-you-age-what-you-can-do-now/
Most Common Side Effects of Antidepressants + Natural Remedies for Depression
May 12, 2018 09:16 AM
If you are one of the millions of people battling depression, it is important that you understand the side effects that antidepressants oftentimes bring with them. These pills are the most common treatment for depression, but it does not come without its risks. Once you learn the potential risks that can come when taking these antidepressants, you may very well want to consider using some of the natural remedies for the mental health illness instead.
"Many physicians and researchers have expressed concern that the benefits of these drugs simply don’t make up for the major side effects of antidepressants."
Read more: https://draxe.com/side-effects-of-antidepressants/
Vitamin D is so important researchers worry about ethics of limiting supplementation to perform research trials
April 15, 2018 05:17 PM
In order to effectively study vitamin defriciencies, many pharmaceutical agencies hold controlled studies that are overlooked by medical physicians. These are typically done by giving some participants the vitamin supplement, while others get a placebo. In the case of vitamin D, however, experts are labeling studies to be unethical because of the potential damage that participants could face if they become deficient while on the placebo due to their vitamin D levels dramatically dropping to an unsafe level.
"In case you needed any more proof of how essential vitamin D is to good health, researchers have warned that placebo-controlled trials that involve limiting some people’s intake of the all-star nutrient could be considered unethical."
Read more: https://www.naturalnews.com/2018-04-13-vitamin-d-is-so-important-researchers-worry-about-ethics-of-limiting-supplementation-research-trials.html
12 signs you're not getting enough calcium
September 14, 2017 12:14 PM
Calcium is the most abundant mineral in the human body and is essential for many of our important body functions. The problem is, most of us are not getting enough of it in our diets. Calcium deficiency can lead to many problems including heart disease and obesity. Here are some signs that you are deficient in calcium. These signs range from broken bones to altered mental states. If you suspect that you were not getting enough calcium you may want to check out this list to see if you have any of the signs.
"Calcium is needed for the mineralisation of bones to keep them strong, so low calcium levels increase the likelihood of broken bones, and osteoporosis in later life."
Read more: http://home.bt.com/lifestyle/health/healthy-eating/12-signs-youre-not-getting-enough-calcium-11364210197295
Boy Who Suffered 100 Seizures A Day Has Zero in 300 Days After Being Prescribed Cannabis Oil
September 11, 2017 09:14 AM
Billy, an 11 year old living in Northern Ireland, will be the first person to receive a medical marijuana prescription in the United Kingdom. Billy suffers from severe epilepsy, which prevented more traditional medical treatments. His doctor agreed to prescribe it in the wake of overwhelming evidence of the success of Cannabidiol in treating his condition. Where previously Billy would experience up to 100 seizures a days - Billy has not experienced a seizure since starting his treatment 300 days ago in the United States. His mother also notes that it has helped with Billy's Autism - making better eye contact when he plays and communicates. To celebrate this largely important decision, the family is hosting an event, that already has 600 RSVP's, in support of Billy.
"Before taking the CBD oil, Billy suffered from up to 100 seizures a day, which was severely damaging to his health, because one seizure could kill him."
Read more: https://www.civilized.life/articles/boy-who-suffered-100-seizures-a-day-completely-cured-with-cannabis-oil/
Olive Oil Can Help Preserve Memory And Prevent Alzheimer's
June 24, 2017 12:14 PM
Alzheimer's disease affects nearly 44 million people worldwide. According to a study done by researchers at Temple University in Pennsylvania, olive oil can help preserve memory and essentially prevent Alzheimer's disease. Dominico Pratico, lead researcher of the study, stated that olive oil helps reduce inflammation and activates a process in the brain called autophagy. Autophagy is a way that the cells in the body break down and clean out unwanted debris in the body. Mice were given olive oil in the study, and the mice that received the olive oil showed signs that the olive oil made their memory improve and lessened the signs of Alzheimer's. The researchers from this study plan to continue researching the effects of olive oil and Alzheimer's in older mice to see if they can eradicate the disease in mice altogether.
"When the team studied the brain tissue from both groups of mice, they noticed "dramatic" differences in nerve cell appearance and function. As compared to the mice that didn't consume the oil, the brain cells of rodents in the oil group showed a dramatic increase in nerve cell autophagy activation."
Read more: http://doctor.ndtv.com/news/olive-oil-can-now-help-preserve-memory-and-prevent-alzheimers-1715610
Jarrow challenges FDA on probiotics
June 05, 2017 11:14 AM
Jarrow Formulas Inc. has released a 32 page comment challenging the FDA on it's stance on probiotics. It notes how the FDA won't approve the term probiotics in several cases, instead using the phrase active cultures and just how the FDA labels probiotics in general. The company also takes issue with the fact that fermentation is considered chemical alteration under the current guidelines. The draft was vetted by the supplement company's lawyers and could dramatically change dietary guidelines if accepted.
Read more: Jarrow challenges FDA on probiotics
9 Reasons to add Chlorella superfood to your diet
May 09, 2017 03:44 PM
Many overlook the importance of establishing and maintaining a healthy diet. Foods such as chlorella can have dramatically positive benefits on those who include it as part of their daily meals. Chlorella is a form of green alga that has a wealth of nutrients, binds heavy metals, supercharges the immune system, improves cholesterol, keeps blood pressure on track, provides a number of additional benefits as well. Thus, adding this superfood may give you the boost that you have been missing!
"Like spirulina, chlorella is a green alga with a host of health benefits. Though it has been around forever, this single-celled alga remained well hidden in freshwater ponds in the Far East until the end of the 19th century."
Read more: http://www.naturalnews.com/2017-05-01-9-reasons-to-add-clean-chlorella-to-your-diet.html
What's The Difference Between Pre & Probiotics?
May 09, 2017 11:44 AM
Maintaining good digestive health is paramount to overall good health and physical well-being. Much of digestive health is predicated on the balance of bacteria in the digestive system, because it dictates how well nutrients are absorbed as well as the ability to fight infection. Ignoring issues associated with digestive health may lead to problems such as inflammatory bowel disease, diabetes, and other issues that can have a dramatic influence on the overall health of a person.
"Research is showing that our gut flora performs pivotal roles in metabolism, nutrient digestion, absorption and synthesis, as well as immune function, hormonal regulation and disease prevention."
Read more: https://www.thehealthychef.com/2017/05/whats-the-difference-between-pre-probiotics/
Food NOT Chemo Holds ‘Cure’ For Colon Cancer
March 17, 2017 03:59 PM
Chemotherapy has long been the chosen therapy for patients suffering from cancer, but if you have colon cancer, perhaps it is not chemo that you should be interested in. Instead, perhaps it is the foods that you are eating that you should consider. How does the food that you eat help with colon cancer?
"Colon cancer is one of the world’s most prevalent and lethal forms of cancer and is believed to be driven primarily by the Western diet."
Rewires Your Brain and Slashes Anxiety Levels, but Beware
March 14, 2017 03:59 PM
Thedocumentary, Ride the Tiger: A Guide Through the Bipolar Brain, focused on current concepts treatment. Drugs available don't work in all patients and lifestyle changes are recommended when possible. It's recommended that bipolar patients and people suffering from other disorders There has been some positive outcomes from devices using light and magnets to stimulate the brain but a healthy diet, exercise, vitamin supplements and probiotics can address these disorders. Patients have also received benefits through exercise and proper sleep patterns. Doing all this, patients have found they can slowly get off their drug treatment regimens.
""By seeking to understand how the bipolar brain malfunctions, researchers believe they can get closer to understanding the inner workings of the brain, potentially unlocking treatments for other types of psychiatric problems as well.""
Alabama dad shares cannabidiol oil's positive impact on daughter's seizures
March 11, 2017 05:59 AM
Evidence is mounting that marijuana provides several medical benefits and more states are legalizing it for medical use. Tennessee lawmakers are currently debating legislation called Carly's Law which was named after a young girl named Carly Chandler who was treated with Cannabidiol (CBD) oil for seizures to great success. Dustin Chandler, Carly's father, speaks out about how CBD oil dramatically decreased his daughter's seizures and why the legislation is so important to patients like Carly.
Read more: Alabama dad shares cannabidiol oil's positive impact on daughter's seizures
10 Reasons to Start Drinking Bone Broth
January 23, 2017 02:59 PM
If you would like an inexpensive way to make yourself healthier, look no further than bone broth. The bones used to make these broths are full of nutrients that can help with multiple issues. Just a few of the benefits include boosting the immune system, reducing inflammation, assisting in bone repair, and boosting hair and nail growth.
"Bone broth, the old-timey staple that's making a Dramatic comeback is the latest superfood sweeping the country, and for good reason. It's said to contain several health benefits as well as ingredients to make us look younger, and it's a cheap, easy to prepare comfort food."
Top 5 weight loss tips of 2016
December 16, 2016 10:59 AM
Keeping yourself in a healthy weight range is very important. It can ward off disease and different types of cancer, but it is easier said than done. There are some tips to help lose weight this season. Brushing your teeth after you eat can aid in weight loss, and also making sure the changes you make are not too drastic can help keep you motivated to lose weight.
"Weight loss doesn’t start at the dinner table or even at the grocery store; it starts in the kitchen"
This simple ancient Japanese technique helps improve physical and mental health
December 08, 2016 04:59 PM
Jin Shin Jyutsu physio-philosophy is an art of harmonizing the life energy in the body. Born of innate wisdom and passed down from generation to generation by word of mouth, the Art had fallen into relative obscurity when it was Dramatically revived in the early 1900's by Master Jiro Murai in Japan.
"To prevent health problems, we must sincerely understand what makes our organs work, how they are connected and energized."
Can Chitosan Really Absorb Fat?
June 06, 2014 05:11 AM
What is a chitosan
Chitosan is a naturally produced supplement that is recommended by nutrition experts and doctors as a great remedy for weight loss and high cholesterol, which results in a lower risk to develop bothersome cardiovascular problems and facilitates a better looking physique. Chitosan is made from the outer shell of crustaceans, such as shrimp or lobster. The outer shell is processed and a special form of "sugar", also known as a polysaccharide, is obtained. Unlike other types of artificially created sugars, Chitosan possesses unique properties that make it a great addition to a healthy diet for individuals who want to manage their weight and prevent obesity.
November 22, 2012 11:03 AM
Among beverages, many varieties of tea exist including oolong, green and black tea. they are in fact quite similar in their natural state and chemical composition. However, the benefits of black tea extract has begun proving its mettle after the rather heavy overdose of information and research on green tea. The important ingredient that has made tea a rage in alternative medicines in the modern times is the contents of polyphenol which is beneficial in reducing fat absorption and aiding weight loss. In fact, while green tea extract has about 30-40% of water soluble polyphenol, black tea has about 10% .
What has however been proven through recent clinical studies is that the four kinds of polyphenols found in black tea extract are more active on adipose tissue mass, liver lipid content thereby suppressing body weight more effectively as compared to green tea. Green tea is the fresh plucked leaves of the camellia sinesis plant while black tea extract is made from the fermented leaves. While the green tea leaves are only lightly dried, black tea leaves are fully oxidized. Both contain flavonoids known for their beneficial effects on the human body .
However because of the excessive oxidation in black tea, the flavonoids convert to complex theaflavins and thearubiglins.These are antioxidant known to be tremendously potent in effectively countering cancers, stroke and heart ailments. Potent Health Benefits *Its proven to affect on triglycerides present in the blood thus affecting body weight issues Dramatically. In fact clinical observations have proved that it induces reduced levels of cholesterol with no side effects on fat soluble vitamins.
It's safe usage could not have been proved better:
An intake up to three cups is said to have beneficial effect but again discretion should be maintained in cases of hypertension, blood pressure and anxiety, who could do without the effect black tea extract has on blood circulation and heightening of alertness.Without a doubt black tea extract remains one of the most common proven natural formulas with great benefits.
Health benefits of Omega 3-6-9 fatty acids
March 08, 2012 06:50 AM
What AreThe Benefits Of Omega-3-6-9?
In order to maintain the normal function of the body, it is important that our diet consists of the right amounts of various fatty acids. These are organic compounds made up of carbon chains of various lengths, with one end having an acid group and a hydrogen on the end all attached to the carbons in the chain. Omega-3-6-9 fatty acids are vital ingredients that play important roles in the body.
Omega-3 fatty acids are referred to as essential fatty acids because they cannot be synthesized in the body and must be obtained from foods such as nuts, fish or plant oils such as canola and sunflower. These essential fatty acids exists in three types, alpha-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid each with an important role to play in the body.
The alpha-linolenic acid help to reduce the high risks of stroke and heart disease by lowering cholesterol level and slowing down the production of harmful triglyceride in the liver while at the same time raising the level of high-density lipoproteins, HDL or good cholesterol in the body. They also prevent the accumulation of harmful fat in the arteries and promote the elastic nature of the blood vessels.
Both eicosapentaenoic and docosahexaenoic acids promote the development of the eye and brain, reduces risks of cardiovascular diseases, and may aid in preventing Alzheimer's disease. A study based on eicosapentaenoic and docosahexaenoic acids conducted on a ten year period on individuals who had high risk of death from heart disease revealed a 40% decrease in cardiovascular disease and a Dramatic reduction in mortality rate.
Omega-6 fatty acids are also essential fatty acids that cannot be produced by the body and must be obtained from chicken, eggs, dairy products and various plant oils such as corn oil, rice bran oil among others. In association with its derivative, the alpha-linoleic acid they aid in production of prostaglandin which plays a vital role in promoting the normal function of the brain, nerve and immune system.
They also help in reducing incidences of coronary artery disease by lowering the level of cholesterol in the arteries. By consuming the right amounts of essential fatty acids, a balance is achieved and both essential oils work synergistically to promote the overall health of the body by preventing various inflammatory disorders.
Omega-9 fatty acids are a class of unsaturated fats commonly found in animals fats and vegetables and are also called monosaturated fats or oleic acids. They are usually produced by the body unlike the essential fatty acids but can also be obtained from various plant oils such as sunflower, olive, canola as well as other mono-saturated fats. Research studies have revealed that the mono-saturated fatty acids may help in reducing the risk of stroke and cardiovascular diseases.
This is because, they have been found to play an important role in increasing the level of high-density lipoproteins or good cholesterol and decreasing the level of high-density lipoproteins or bad cholesterol in the body. They also prevent the unwanted plaque deposits in the arteries and this reduces the risk of developing coronary artery disease. Despite the fact that Omega-3-6-9 individually play different roles in the body, it is clear that striking a balance of the essential fatty acids plus non-essential fatty acids is important for promoting the overall health of the body.
What Are the Health Benefits of Phosphatidyl Serine
February 21, 2012 07:53 AM
Phosphatidyl Serine is a phospholipid produced by the brain that brings about a number of beneficial effects to the human body. It is found in every cell of the body but it is abundantly available in the brain. Though it is manufactured naturally in the brain, this type of fat can also be derived from meat, vegetables, dairy products and supplements. In fact, lots of Phosphatidyl Serine supplements are offered on the market today because of its helpful benefits to the human body. So what are the health benefits of Phosphatidyl Serine?
Basically, Phosphatidyl Serine is a powerful nutrient that improves the cardiovascular and overall fitness and boosts the cognitive function of an individual. It increases one's mental clarity, focus, concentration and alertness. Phosphatidyl Serine is actually considered as ‘brain food' that nourishes and enhances the functions of the brain even at an old age. Intake of Phosphatidyl Serine can significantly reduce the individual's risk of suffering from life threatening diseases. In fact, clinical studies show that Phosphatidyl Serine contains powerful components that prevent an individual from developing hypertension and treat atherosclerosis.
Phosphatidyl Serine and Memory
Phosphatidyl Serine is also proven to be effective in boosting the cognitive function of the user. Studies show that the phospholipid can significantly enhance the focus and concentration of an individual. Furthermore, it improves one's learning abilities and helps in alleviating the symptoms of age-related memory loss. This type of fat regulates the production and release of neurotransmitters in the brain. Phosphatidyl Serine is also effective in preventing the development of dementia and treating it.
Studies show that production of Phosphatidyl Serine in the brain decreases with age. This results to the increased occurrence of age-related memory problems as one gets older. Phosphatidyl Serine is even effective in treating the symptoms of Alzheimer's disease that is mainly triggered by a disruption in the normal functioning in the part of the brain that controls memory, thought and language. Intake of 300g of Phosphatidyl Serine daily for two months can reduce the symptoms of the debilitating condition.
Some studies revealed that Phosphatidyl Serine has the ultimate capacity to boost the health of the cell membranes and lower the level of stress hormone in the body. This substance is also believed to be effective in reducing the impact of stress to an individual. Phosphatidyl Serine combats exercise-induced stress by reducing the level of cortisol produced by the adrenal glands during stressful situations.
A clinical study in 1990 shows that intake of Phosphatidyl Serine can significantly reduce the symptoms of depression in elderly women. Researchers claimed that depression is mainly triggered by chemical imbalances in the brain or a stressful event such as accidents and death of a spouse, children and relatives. By mitigating the impact of stress, Phosphatidyl Serine prevents the occurrence of the debilitating symptoms of depression.
Phosphatidyl Serine is also beneficial in building muscles during workout and endurance trainings. It Dramatically increases the recovery time of the muscle builders between workouts. It reduces muscle soreness during workouts and increases the physical performance of an individual.
Some researchers claim that Phosphatidyl Serine can help children who have been diagnosed with ADHD. Furthermore, the substance is believed to be effective in regulating the mood of the user.
Natural Remedies To Control Blood Sugar
June 17, 2010 01:32 PM
Diabetes has now been found to be the seventh leading cause of death in the United States and Canada. It is a chronic disorder of carbohydrate, fat, and protein metabolism. The disease starts off as a variety of metabolic changes that are associated with hyperinsulinemenia and hyperglycemia. When this happens, Insulin Resistance Syndrome results, which is a precursor to actual, full-blown, diabetes. If left untreated, insulin resistance will develop into full-blown diabetes, which includes greatly magnified risks of heart disease, stroke, eye and kidney disease, and loss of nerve function. It should be noted that diabetes is the principal cause of adult blindness and limb amputation.
Type 2 diabetes is the most common form of diabetes. In this type of diabetes, the body either does not produce enough insulin or the cells ignore the insulin. Insulin is crucial for the body to be able to use glucose for energy. The body breaks down all of the sugars and starches that you consume into glucose, while insulin takes the glucose from the blood into the cells. When glucose builds up in the blood instead of going into the cells, the cells may be starved for energy immediately, and high blood sugar glucose levels over time can cause damage to your eyes, kidneys, nerves, and heart. Diabetes occurs in people of all ages and races, with some groups having a higher risk for developing it than others. Diabetes is more common in African Americans, Latinos, Native Americans, and Asian Americans, as well as the older aged population.
Non-insulin-dependent diabetes, also known as type 2 diabetes, is a disease that is strongly associated with a sedentary lifestyle and the modern western diet. Inadequate physical activity, along with a diet that is high in refined sugars, saturated fats, and proteins, and simultaneously low in dietary fiber has resulted in an obesity epidemic throughout the United States and Canada. With this epidemic has risen the prevalence of type 2 diabetes. In fact, obesity is a main factor in type 2 diabetes, with almost 90% of those diagnosed with type 2 diabetes being obese at the time of diagnosis. Although there is still a disagreement as to whether obesity actually causes type 2 diabetes or whether diabetes causes obesity, there is one thing that is clear: the disease involves a huge disturbance to the metabolic balance of the body and weight is a major factor in blood sugar management. This disturbance leads to Dramatic consequences for the individual.
In order to reduce the risk of type 2 diabetes, it is crucial that one prevents the onset of insulin resistance. Unfortunately, millions of North Americans unknowingly suffer from this syndrome. This places them at an increased risk for cardiovascular and neurological dysfunctions. Research has shown that complications that are associated with the development of insulin resistance may be mitigated effectively by conscientious dietary and lifestyle changes along with weight loss.
Vitamins B3, B6, B12, C, E, biotin, coenzyme Q10, and the trace elements chromium, magnesium, manganese, and zinc are all crucial for proper blood sugar defense and metabolic support, as well as the regulation of glucose metabolism. Supplementation with these nutrients at levels that are determined to be suitable for optimal nutritional health by cited nutritional authorities is an important part of product-rating criteria. Nutritional experts ask themselves whether the product in question contains vitamin B3, vitamin B6, vitamin B12, vitamin C, vitamin E, biotin, coenzyme Q10, chromium, magnesium, manganese, and zinc at potencies that are up to 100% of the potencies for these nutrients in the Blended Standard.
Excess weight seems to be a key factor in type 2 diabetes so it seems to reason that reducing body fat can help one improve insulin sensitivity. Losing weight is no easy task but is possible with consistent work. Fortunately, heath food stores have vitamin formulas that may help improve insulin sensitivity, but this is no substitute for good clean eating and exercise. For additional information on these supplements, please contact your local health food retailer.
March 05, 2009 01:31 PM
Inflammation is a normal part of the body’s defense against pathogens. The increase in body temperature, flood of toxic free radicals and inflammation-signaling proteins, and release of killer macrophage cells are the main signs of an inflammatory event that is the body’s long-established means of defending against a clear and present danger. This adaptive response can now become a cause for debilitating disease. It is even thought that the aging process may be linked to the very defense mechanism that keeps us healthy when we are young. As we grow older, our ability to regulate inflammation begins to diminish. Instead of protecting us, inflammation becomes silent and systemic, allowing degenerative disease to take root. The symptoms of silent inflammation are extremely different from acute inflammation of redness, heat, swelling, and pain, and can lie undetected until it has been around for far too long.
Silent inflammation causes the body to turn on itself, as its immune system begins attacking its own organs. Over time, inflammatory cytokines such as C-reactive protein, interleukin-6, and inflammation producing eicosanoids like prostaglandin E-2 and leukotrienes B-4, start to destroy tissue all over the body. In response to this attack, the body produces even more inflammatory cytokines and free radicals, which creates a self-perpetuating cycle. Silent inflammation damages arteries, destroys nerve cells and organs, compromises the immune system, and promotes cancerous growths. Despite how well they feel today, those with silent inflammation are on a fast track toward degenerative disease. On the good side, preventative measures that are taken today to reduce inflammation can prevent degenerative diseases like cardiovascular heart disease, cancer, diabetes, and Alzheimer’s tomorrow.
When there are equal numbers of good and bad eicosanoids, a state of wellness is able to prevail within the body. However, when they become chronically unbalanced, many problems result. This balance is, interestingly, highly dependant upon the level of insulin that is found in the body. High insulin levels, whether they are induced by sugar overload, the onset of insulin resistance, or the hormonal effects of excess fat, set the stage for systematic inflammation. As insulin levels climb, oxidative stress increases Dramatically, causing the production of inflammatory cytokines. Along with being too high in refined sugar, the average North American diet is filled with inflammation-promoting fats and scarce in inflammation-reducing omega-3 fats; the consequence of this chronic fatty acid imbalance in an increase in systemic inflammation.
As inflammation rises, so does the production of cortisol, which is produced in the adrenal glands and is intricately involved in the body’s response to stress. In an attempt to reduce inflammation, cortisol increases blood pressure, elevates blood-sugar levels, and suppresses the immune system. This means that systemic inflammation produces chronically elevated levels of cortisol, which then place a heavy physiological burden on all organs, causing a Dramatic increase on the risk of degenerative disease.
Fortunately, changing the balance within the body to favor the production of anti-inflammatory eicosanoids can be achieved through a conscious dietary change. By simply increasing your dietary intake of fatty fish, eating raw nuts and grains rich in healthy fats, and supplementing with a high-quality cold-pressed fish oil or flaxseed oil, and concurrently decreasing your intake of red meats, eggs, high-glycemic foods, and foods high in saturated fats, chronic inflammation can be reduced greatly. Vitamin supplements can boost ones antioxidant intake and help fight inflammation as well. Quality vitamins are available at your local or internet health food store.
Red Pepper, Cayenne, Capsicum
December 18, 2008 04:51 PM
A remarkable whole body stimulant, Capsicum can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain, and fight off infection. One study on African plants found that Capsicum, when regularly ingested, is highly beneficial in hemorrhoids varicose veins, anorexia, liver congestion, and vascular conditions. The therapeutic actions of capsicum can be attributed to the alkaloid or glucoside content of the herb.
Capsicum boosts peripheral circulation and stimulates organ secretion as it expedites the therapeutic delivery and action of other herbs. This allows the medicinal benefits of these herbs to reach the inflamed tissue more rapidly because of enhanced blood flow. Cayenne insures rapid and even distribution of the active parts of the rest of the herbs to critical parts of the body, which include those that are involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation.
For this reason, cayenne is included in many other blends, as even extremely small quantities can Dramatically increase the efficiency of most other herbs. Capsicum stimulates everything from blood flow to peristaltic action in the stomach, to intestinal transit time. Capsicum’s ability to stimulate organ secretion and heart action makes it one of the strongest natural stimulants that are known.
Capsicum is also known to be unequaled in its ability to boost circulation and increase heart action. Cultures that consume significant amounts of cayenne pepper in their diets have been found to have lower rates of cardiovascular disease. A variety of desirable actions on the entire cardiovascular system can be produced by Capsicum, with its extraordinary ability to enhance cardiovascular performance and lower blood pressure. Capsicum is considered a superior food for the heart by herbalists, where capsicum in hot water is thought to help lessen the severity of heart attacks.
Many studies have also been done on Capsicum’s ability to reduce the risk of developing atherosclerosis by reducing blood cholesterol and triglyceride levels. When cayenne is ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels that ordinarily results was significantly inhibited. Additionally, bile acids and free cholesterol were subsequently eliminated from the body through the stool.
Another bonus of Capsicum is its ability to lower blood serum cholesterol, as it decreases blood pressure. There is additionally evidence that suggested that the herb is able to initiate other mechanisms that help in fighting hypertension. Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it is not shocking that is also facilitates the faster removal of toxins from the blood stream and lymphatic system.
Additional benefits of Capsicum include its ability to boost the circulatory system, as it has the ability to help in preventing cold hands and feet, as well as Reynaud’s Syndrome. Capsicum also has antioxidant capabilities, making it a great scavenger of free radicals. Anti-cancer research has also found that Capsicum does demonstrate anticancer properties, as it inhibits certain enzymes that initiate the mutation of cells. This implies that taking Capsicum can give the body some protection against cellular mutation.
Capsicum has also been found to be an impressive pain killer, an anesthetic to ulcerated tissue, an aid in weight loss, a helper in psoriasis and rhinitis, and a reliever of fevers and chills. The list goes on and on, about the benefits of this amazing herb. Cayenne or red pepper can be found at your local health food store.
Alpha Lipoic Acid
December 11, 2008 11:19 AM
Alpha lipoic acid is the ideal antioxidant for five main reasons. It can scavenge free radicals of all kinds of both fat and water-based cell structures. It rapidly assimilates and absorbs into cells. Alpha lipoic acid boosts the action of other protective compounds. It chelates free meal ions and it also promotes normal cell replication.
Alpha lipoic acid (ALA) is both fat and water soluble, which makes it a superior free-radical scavenger because it can protect lipid (fat) and aqueous (water) cell parts from free-radical damage. This ability allows ALA to offer excellent cellular protection because it can easily transport across cell membranes and give oxidant protection outside and inside cell structures. ALA has the ability to freely move throughout all cell parts, scavenging for free radicals in a way that is definitely more effective than other antioxidant compounds. Vitamin C, for example, is a good antioxidant but is strictly water soluble and only affects the interior of cells. On the other hand, vitamin E is only fat soluble, meaning that it affects only the lipid portion of cell structures or the membrane, which leaves other areas unprotected.
Cellular glutathione, which is produced in the body and works to neutralize free radicals, is very difficult to artificially boost. Although oral glutathione supplements are available, they have to go through the GI route before they enter the blood stream, leaving little glutathione which actually survives this process. Because of this, cellular levels are not significantly increase by oral supplementation. ALA has been found to help regenerate glutathione by providing extra cellular protection.
If the body becomes deficient in ALA, other antioxidant compounds may not work well. ALA plays an important role in boosting the activity of protective compounds such as vitamin E. ALA Dramatically extends the life and effectiveness of other vital compounds.
ALA has been used for decades to treat diabetic conditions and complications including diabetic neuropathy, with ALA actually having the ability to initiate a reverse in the condition in some cases. Additionally, ALA helps to boost glucose uptake and results in less insulin dependency in some cases. Among its other properties, ALA can protect brain tissue on a cellular level, as well as protect brain cells from certain hazardous chemicals.
Research has shown that ALA may even play a role in the treatment of neurological disorders such as Huntington’s disease. As we are all aware, LDL cholesterol has a huge role in the development of cardiovascular disease. LDL cholesterol, which is particularly susceptible to free-radical damage, can be protected by ALA from free radical damage itself. Along with the above properties, ALA has been shown to help in strokes, cancer, cataracts, HIV, liver regeneration, and detoxification.
ALA can be purchased in tablet and capsule form and works well when it is orally ingested so that it can be easily assimilated through the walls of the gastrointestinal tract. Taking between 40 to 50 mg of ALA is recommended for best results. The primary applications of alpha lipoic acid are aging, aids, alcoholism, atherosclerosis, bell’s palsy, cataracts, cancer, cirrhosis, diabetes, diabetic neuropathy, multiple sclerosis, liver disease, radiation sickness or exposure, Alzheimer’s disease, senile dementia, stroke, Huntington’s disease, Parkinson’s disease, and heavy-metal poisoning. Have you had your alpha lipoic acid today?
Control Blood Sugar Naturally
October 01, 2008 12:10 PM
Your blood glucose level is generally controlled by insulin and glucagons, both of which are biosynthesized in the pancreas. Insulin works by making the glucose bioavailable to the mitochondria to convert into energy, while glucagon, the lesser known of this twosome, stabilizes the level of insulin and mobilizes it to do its job. There are two types of diabetes, known as Type I and Type II or A and B.
Type I diabetes, also known as juvenile onset diabetes, is an autoimmune condition in which the immune system destroys Beta cells because they are recognized as being foreign. It is the Beta cells that generate insulin, and so the condition can be fatal. Patients with Type I diabetes must take insulin throughout their lives, and while potential cures are currently under investigation, none are yet available. Although insulin can be effective it does not guarantee survival, and a better form of treatment is required.
Type II diabetes is by far the more common of the two, and is a form of resistance to insulin, where the body cells cannot use insulin properly. The pancreas initially reacts to this by producing more insulin in response to the increased blood glucose level, but through time it loses its ability to produce insulin as a reaction to an increase in blood sugar, even though this occurs as a result of digesting a meal.
The exact causes of either type of diabetes are not known for sure, although the general mechanism by which they work is known. However, Type II diabetes is believed to be due to some form of interaction between genetics and environment, and it is known that the majority of Type II sufferers are obese and also over 40.
The treatment for this type of diabetes is rarely insulin, but a controlled diet, control of your cholesterol level and blood pressure, exercise and specific medicines designed for sufferers of this form of diabetes. However, there are also natural supplements that can be used to control your blood sugar levels. Diabetes was the sixth leading cause of death of the USA in 1999, with 450,000 deaths, and by 2005 had reached about 300 million sufferers world wide. It is therefore a serious and widespread condition, though Type II is less serious than Type I.
It is important to do what you can to control your diabetes, since after several years it can lead to problems with your nerves, eyes, kidneys and gums, and can also lead to heart disease. With diabetes you are at least twice as likely to have a stroke or heart problem as those without it, although you can reduce the risk of this by keeping your blood pressure under control, and the levels of fats in your blood to a minimum. Stopping smoking helps, and there are some natural treatments that can also help you control your diabetes.
The most important means of control is to reduce your blood sugar levels. While there are natural products that will help you to do that, do not stop taking the medication prescribed by your doctor, but use these in addition to what you are already taking. Among specific substances that can help are:
Chromium: chromium helps your body to use insulin properly. When taken in the form of chromium picolinate, it helps to replace chromium that diabetics appear to be short of. Human studies have indicated that chromium can decrease insulin levels and improve the metabolism of blood sugar in those with Type II diabetes. Some claim that chromium is harmful to health, but the general opinion is that it helps, though you should consult your doctor before using it.
Cinnamon: If you take cinnamon daily, your blood sugar levels should gradually decrease. It appears to enable your cells to make better use of the insulin your blood, although there still discussion as to the mechanism by which this occurs and of the active ingredient in cinnamon that promotes it. Some claim it to be a flavonoid known as methylhydroxychalcone polymer, or MHCP. However, others claim it not to be MHCP, but polyphenol type-A polymer. Whichever it is, many people are finding cinnamon to be effective in reducing high levels of blood sugar to a more manageable level.
Milk Thistle: It is known that antioxidants can help to control blood sugar, and the flavolignins in Silymarin marianum, an herbal extract available from milk thistle seeds, work in this manner. It is also good for protecting the liver from toxins. Although it is not clear how it is done, silymarin appears to help to control Type II diabetes possibly by way of liver digestion of sugars in the blood. The liver processed glucose and improving its function through the consumption of milk thistle could help reduce blood sugar as well. Mulberry: The Chinese make what is known as “sugar control herbal tea” from mulberry leaves, green tea and jasmine. Mulberry leaves contain adenine, pectin and choline, and also high levels of Vitamins A and B types. This tea is used by the Chinese to control blood sugar levels, which might occur through the antioxidant effect of the mulberry constituents.
Salacia oblonga: This is an herb used in India and Sri Lanka that appears to cause a Dramatic drop in the levels of insulin and sugar in the blood. It binds to enzymes in the intestine that break carbohydrates down into sugars, and so reduces the amount of sugar in your blood. That in turn reduces the amount of insulin released by the pancreas.
Apple Cider Vinegar: There is evidence that apple cider vinegar can help to control your blood sugar levels if taken before a meal. Just two tablespoons appears sufficient to give a noticeable result. This is one of those home remedies that might be just anecdotal, but might also work, so is worth trying.
Zinc: It has been discovered that diabetics suffer a deficiency in zinc. This mineral plays a part in the storage and production of insulin in your body, and a deficiency could cause an increase in your sugar level. Oysters, pecans, almonds, lamb and chicken are all good sources of zinc.
Glyconutrient complexes: we know that diabetes is an autoimmune disease for type I individuals. Supporting a properly function immune system requires a good diet as well as a diet rich in Glyconutrients. The polysaccharides found in glyconutrient formulas can help the immune system communicate better with the body and just possibly correct some autoimmune diseases which attach our cells.
These are the natural supplements that people are taking to help control their blood sugar and diabetes. It is important that you take nothing that interferes with the medicines given to you by your physician, so you should let your doctor know of any natural supplement that you are using in addition to your prescription medicines. However, it is possible to control your blood sugar with natural supplements, and those mentioned above are just a few of the natural substances available that can help diabetics control their condition and so avoid the side effects.
Gac Fruit Oil
August 25, 2008 07:04 PM
Most people have never heard of gac fruit, yet it is very popular in South East Asia, particularly in China and Vietnam. The fruit is grown on vines that reach the size of a cantaloupe and from North East Australia across to China and Vietnam it is used as both a food and a medicine. It is only fairly recently that it has found use in the West as a health food
So what’s so special about this fruit, known also as baby jackfruit and sweet gourd? Its bright red color should provide a clue, since it is jam packed full of beta carotene, lycopene and other strong antioxidants that not only helps to support the immune system, but also helps to retard the effects of aging. It has been used in Vietnam in particular to overcome the effects of an endemic deficiency in vitamin A, and is rich in provitamin A carotenoids. It is also widely used in Chinese medicine to treat a variety of complaints.
Antioxidants and Free Radicals
Antioxidants can boost health in a number of ways, and it might help you understand better the benefits that gac fruit can provide to explain what antioxidants do and why they are such an essential part of our diets. Every millisecond of every day of our lives, our natural metabolism of the conversion of blood glucose to energy generates small oxygenated molecules known as free radicals.
Free radicals are molecules that possess an unpaired electron and are highly unstable. Electrons generally travel in pairs, and when one of that pair is lost through a chemical reaction, the other electron has only one purpose in its short life: to pair up with another electron and it will do whatever it has to in order to achieve that. It is called a free radical, and its life is short. Free radicals destroy body cells, and this can have a Dramatic effect, both visually on your skin, and internally on your general health.
Apart from those generated by your body’s own biochmemistry, free radicals are present in car emissions and other pollutants such as pesticides, smog and fried and barbecued foods. They are also formed in your skin by excessive exposure to the UV component of the sun’s radiation. That is why the skin of those living in hot climates tends to age earlier.
Free radicals are what make you look older as you grow older: they destroy skin cells as they are formed, but that is one of the least of their effects. They can also oxidize low density lipids (LDL) that carry cholesterol around your body, causing it to deposit fatty plaques on the walls of your arteries, which is a serious cardiovascular condition known as atherosclerosis.
Antioxidants can donate an electron to free radicals without then becoming free radicals themselves, and so destroy them as they are formed. However, the antioxidant can then lose its reducing power. Free radicals do not roam the blood seeking victims as many imagine them to, but react almost instantly, as soon as they are formed. It is important, therefore, that antioxidants are present in or close to every cell of your body. To achieve this, they must be bound to a fatty molecule, and the problem with many phytonutrients is that they have no associated fats or oils to carry them into the fatty tissues of the body.
Nutritional Constituents of Gac Fruit
Not so with gac fruit, because in addition to the beta carotene and lycopene content, it is also rich in long-chain fatty acids, particularly linoleic and alpha linoleic acids. Not only that, but its beta carotene content is around ten times that of carrots, and it contains 70 times the lycopene of tomatoes! Vitamin C is another very powerful antioxidant, and gac contains 60 times the Vitamin C of oranges. It is also rich in other free radical busters, such as xeoxanthins and alpha-tocopherol, a form of vitamin E.
Altogether, gac fruit contains a free radical killing arsenal that should be enough to scare even the most courageous free radical back to where it came from. Other constituents of gac are numerous minerals, particularly zinc and iron.
That is why the sweet gourd is such a prized fruit, and why Southeast Asian women have skins that western women of the same age would die for! Antioxidants help to prevent the disruption and destruction of skin cells that are the major reason for aging looks, and why skin creams are packed with vitamins A and E, both strong antioxidants.
Health Benefits of Gac
Most of the health benefits of gac are provided by its antioxidant properties. Thus, if you have a high cholesterol level, gac can help you to avoid atherosclerosis by preventing the oxidation of the LDL cholesterol, which is the precursor to it depositing on your artery walls. The body needs cholesterol, but levels should be kept to within certain limits or the resultant atherosclerosis can narrow your arteries leading to cardiac problems and strokes, particularly in the very narrow arteries of the brain.
Gac also supports the immune system and helps to maintain prostate health, largely through its alpha tocopherol, or vitamin E content. Vitamin E is easily destroyed by free radicals, which is where the beta carotene is of benefit. This is the body’s first line of defense against free radicals, and each molecule can neutralize up to 20 free radical molecules before it is destroyed. This helps to save other antioxidants such as vitamin E.
Lycopene is particularly beneficial to the prostate and current research indicates that it can help to prevent prostate cancer and cardiovascular disease, plus some other diseases such as macular degeneration that affects your sight. Perhaps this is one reason why the gac fruit membranes are used in Vietnam to promote healthy vision, and they also help to cure dry eyes. Lycopene remains in your body fat longer than normal beta carotene, and recent studies have found that men with high amounts of lycopene in their body fat are up to 50% less likely to suffer heart attacks as those with low amounts.
Gac fruit is jam-packed full of nutrients and antioxidants, and has no known side effects. It is used in Asia for weddings and other special occasions, and is grown on lattices in many gardens, although it has a short season. However, gac fruit is not known as the “Fruit from Heaven” for no reason, and if you were allowed the choice of only one fruit in your life, then this would be the one.
August 15, 2008 11:53 AM
In the recent past, DHEA has shown scientists its amazing abilities within the human body. Clinical tests have created a huge amount of interest for both scientists and consumers, with estimates of about 500 in-depth clinical studies on DHEA taking place. These tests, which have been conducted at some of the most prestigious medical research centers and universities in the country, have proven DHEA to be one of the most important anti-aging and anti-disease substances of the 21st century.
DHEA is a crucial and important hormone that is produced in the adrenal glands. It is often called the mother hormone, as it forms the base for the biochemical actions of hormones like testosterone, estrogen, progesterone, and corticosterone. These hormones control important body functions that determine metabolism, energy output, endocrine mechanisms, and reproductive capabilities. DHEA directs the entire endocrine systems through activating and inhibiting enzymes. In its many clinical studies, DHEA has shown an unusually wide variety of physiological benefits. Although it has been known for many years that DHEA is made by the adrenal glands, the function of DHEA in the body has only been recently studied.
DHEA is produced by the adrenal glands, but it can also be found in non-patented prescription drugs and other over-the-counter forms. A lot of these supplements contain a synthetic DHEA-S. A lot of people consider Dioscorea extract, which can be found in Mexican Wild Yam, to have a natural source of DHEA. There are a lot of naturally occurring compounds that can mimic the actions of DHEA and, at the time, do not require a prescription. Wild Yam and Mexican Yam can give a botanical precursor of DHEA, which is considered a substantial source by a lot of health advocates. A great number of studies on DHEA that is derived from Mexican Yam have been conducted, with results concluding that DHEA derived from Mexican Yam and Dioscorea extract is a great idea. However, some controversy surrounds the value of Wild Yam as a valuable source of DHEA.
DHEA is used in the body to make other hormone, as it is the most dominant of all the hormones present in the body. It contributes to the proper growth of brain cells, inhibits the conversion of carbohydrates to fats, decreases the formation of blood clots, regulates hormones, decreases the stickiness of platelets that can clump to cause heart attacks and strokes, increase estrogen in women and testosterone in men, lowers LDL cholesterol, enhances overall immunity, and decreases symptoms of an enlarged prostate.
DHEA helps to reduce menopausal symptoms, promotes thermo genesis, helps to increase muscle mass, stabilizes blood sugar, inhibits appetite and discourages eating, boosts endurance, inhibits diseases associated with aging, helps to restore collagen and skin integrity, fights fatigue and depression, helps to inhibit certain tumors, improves calcium absorption to discourage osteoporosis, acts as an anti-inflammatory, and helps to lower blood pressure.
DHEA levels Dramatically vary in each individual and can drop as a result of stress or other conditions such as blood sugar, fever, hypertension, nicotine ingestion, alcohol consumption, drinking coffee, and the presence of various diseases. Taking birth control pills and other synthetic hormones can also deplete levels of DHEA. When any of these occur, supplementation is needed. Therapeutic doses range from 5 to 25 milligrams per day which can be found here at VitaNet, LLC.
August 03, 2008 07:49 AM
Feverfew is often used in the treatment of migraines and fever, but it has also long been used as an anti-inflammatory agent. It is thought to be similar to aspirin in the way it reduces inflammation. Aspirin works by blocking the production of prostaglandins, which cause inflammation in the body, among many other functions. Similar to aspiring and other anti-inflammatory drugs, feverfew works to inhibit the production of prostaglandins, which reduces inflammatory reactions that occur in the body. Not only may feverfew help with inflammation in cases of pain, but it also helps in cases of arthritis.
One of the oldest diseases known to man, arthritis involves one or more of the movable joints in the body. Arthritis is a general name for a variety of diseases that are characterized by joint pain and inflammation. Striking both the young and old, it is an extremely debilitating condition with symptoms ranging from mild aching to severe pain and deformity. Inflammation can often be found along with the pain, as well as morning stiffness, swelling, and tenderness being common in most cases. Arthritis has been shown to either appear suddenly, or come on slowly over an extended period of time. Diet has been found to be a primary factor in most cases, although some types of arthritis may be inherited or the result of a viral infection.
Conventional treatment of arthritis has involved the use of NSAIDs to help with inflammation and pain, but they do nothing to heal the problem. They may also inhibit the body’s own natural immune function as they temporarily eliminate symptoms. Some evidence has even shown that the use of anti-inflammatory medication for a long time may lead to further joint damage and serious side effects such as gastrointestinal, kidney, and liver problems. Because of this, many people are finding relief with natural healing. Although there are a variety of types of arthritis, the three most common forms are osteoarthritis, in which the joints wear out because of injury or normal wear and tear; rheumatoid arthritis, which is a condition that results from the immune system attacking the body tissue; and gout, which is painful inflammation that results because of excess uric acid in the blood. Rheumatoid arthritis has been found to benefit the most from the use of feverfew. Feverfew may be useful due to its ability to inhibit the formation of inflammation-promoting compounds, with properties similar to NSAIDs but with less potential complications and side effects.
Along with the treatment of arthritis, feverfew has many other possible uses. Included in these uses are: fever, high blood pressure, insect repellent, psoriasis and eczema, menstrual cramps, allergies, digestion, as a sedative to relax and induce sleep, and for its antimicrobial properties to inhibit the growth of staphylococcus aureus and other bacteria.
Because the parthenolide content of feverfew plants vary Dramatically depending on the soil and location of cultivation, it is necessary to buy commercial products from reputable companies who have high quality control measures in place. The best preparations are ones using as little heat as possible, since parthenolide is highly unstable when in contact with high heat, such as freeze-drying. Freeze-dried capsules are extremely easy to use and can easily be found in many health food stores.
(OPC) Grape Seed Extract
May 03, 2008 12:49 PM
Back in the early 1930’s scientists discovered that proanthocyanidins found in grape seeds, green tea, and several other foods are powerful antioxidants that can help the body fight free radicals. Over the year’s research continued to mount on the benefits of proanthocyanidins and in the 1990’s grape seed took the spot light.
Research studies suggested in the 1990’s that moderate use of red wine daily has significant health benefits and mainstream press popularized this notion. Supplement manufactures jumped on the bandwagon and produced a product that was alcohol free with the same benefits of drinking red wine. This was good news for those who don’t want to drink on a regular basis but the manufactures didn’t back up their product with any research at that time.
Proanthocyanidins are a group or class of flavonoids found in many plants as discussed above. Scientists discovered polymecric and oligomeric proanthocyanidins (OPC), but the oligomeric has a smaller molecular weight and can pass through the intestinal walls easier than the polymecric proanthocyanidins (PPC). This means that if you are not consuming the OPC extract for of grape seed then you are probably getting very little benefit from the supplement.
If you are taking a grape seed extract supplement and there is no OPC listed on the label, the manufacture is most likely just tableting or encapsulating crushed grape seeds that aren’t standardized to the most active form OPC. This will Dramatically reduce the cost of grape seed extract, so if you see a low prices grape seed extract at your health food store, be weary of the product if it doesn’t say OPC.
When one consumes true OPC grape seed extract, one can experience many health benefits including cardiovascular benefits. Have you had your OPC Grape seed extract lately?
Boost Skin And Joint Health With Natural Supplements
January 19, 2008 10:37 AM
A lot of health conscious adults are now attempting to keep a youthful appearance for as long as possible by exercising, taking growth hormone enhances, and using expensive cosmetics. However, studies have proven that the major signs of aging in the skin, joints, and eyes occur due to a progressive collagen and hyaluronic acid degradation in our tissues. Researchers believe that supplementation of these key nutrients can actually reverse sings of aging.
Normal functioning of the skin requires that there be normal physiological substances in and around the skin cells. Of the many substances that are required for normal functioning, collagen is one of the most important. Collagen provides structural support to skin, which helps to maintain skin tone, subtleness and elasticity. All of these give the skin its amazing beauty. Without enough collagen, our body would actually lose any connective properties and its ability to hold together, causing the sagging and wrinkles that are associated with age.
Hyaluronic acid is also a vital component of the skin's structure. HA is a big part of the space between living cells and is also present in both the dermis and epidermis, where it allows skin to retain moisture and acts as a lubricant between the collagen matrix of the skin. Younger looking skin typically has higher levels of HA, but it has been observed that hyaluronic acid content declines as we age, most Dramatically after the age of 50. Most people after the age of 40 have already lost a lot of HA and may require supplementation. High concentrations of hyaluronic acid and chondroitin sulfate are able to reach the corium layers of the epidermis and provide cellar level nourishment to the skin. This then reveals a more vibrant and younger looking complexion.
Doctors believe that osteoarthritis affects more than 20 million Americans, with that number reaching 40 million by the year 2020. Some doctors believe we're headed for an epidemic of degenerative joint disease. Osteoarthritis is a degenerative joint condition marked by the erosion of the cartilage at the ends of the bones. Cartilage is the shock absorber of the joint, with regular wear and tear on the joints eventually softening, fraying, and thinning the substance. Other things that can cause cartilage degradation and osteoarthritis have recently been identified by scientists, including: weak quadriceps muscles, eroding cartilage, and changes in bone structure. Certain genes also play a role in predetermining cartilage status, and left untreated and unchecked, this can become extremely debilitating.
Since normal joint function requires healthy cartilage and bones, one of the most important substances required for the normal functioning of joints is collagen. As we age, it has been observed that there is a decrease in the production and concentration of collagen in the joints. The lack of this vital structure leads to joint pain and inflammation. Common treatments today include the prolonged use of painkillers and anti-inflammatory drugs, steroids, NSAIDs and COX-2 inhibitors which temporarily relieve pain and cover up the symptoms while the disease moves further. More often, these treatments worsen the condition instead of helping it due to their harmful side effects. A natural supplement containing Collagen II can not only halt the progression of arthritis but can also improve the condition and provide relief to sufferers.
Give Your Health A Boost With Silica Hydride A Powerful Antioxidant
January 18, 2008 05:25 PM
Hydride ions are strong proton acceptors and hence fatal to free radicals. Silica hydride is consequently a powerful antioxidant that can be used to protect your body against the ravaging effects of these free radicals that destroy the cells of your body, and due to its other unique properties this is a molecule that could be a very useful participant in the various redox reactions that occur naturally within our bodies every microsecond of every day of our lives.
A free radical is a positively charged molecule that is deficient in an electron. Whereas stable compounds consist of electron pairs, a free radical consists of electron pairs and one unpaired electron. Although such a compound is not stable, it does not immediately disintegrate but grabs the nearest electron it can find. This would normally be an electron in the nearest body cell to it, whether it is a blood cell, a cell in an artery wall or a skin cell. The result is that the cell that loses the electron is disrupted.
Free radicals are formed in the body through its normal biochemistry, and also promoted by pollutants such as cigarette smoke, pesticides and traffic fumes. Excessive exposure to the ultraviolet radiation of sunlight or sunbeds also creates free radicals, as does excessive exercise, believe it or not. As stated earlier, these chemicals have only one purpose in your body: to grab an electron from wherever they can, and in doing so they destroy the cells that make up your body tissue.
This can lead to premature aging, heart disease and many other problems with your health. Antioxidants such as vitamins C and E are important parts of your diet, and silica hydride is an other supplement which has been relatively recently discovered to have antioxidant properties. A component of glacial streams, this substance is generally in colloidal form, or in the form of small particles maintained in suspension by the interaction of positive and negative charges on the surface of the tiny particles of which it consists.
The interface between the silica and water can be saturated with reduced hydrogen to form a surface that is overall negatively charged and can hence neutralize free radicals that are seeking the free electrons available from the negative charge. This is otherwise described as a reducing or anti-oxidant effect. All anti-oxidants play their part in neutralizing the properties of free radicals that result in the destruction of body cells.
This leads to premature aging of your skin, if a skin cell is affected, if it is a cell in your artery wall, then the artery will become damaged, and if a blood cell then you can suffer from any one of a number of abnormal blood conditions. The stealing of an electron from one molecule by another is scientifically termed 'oxidation', and the substances that prevent this from occurring are called antioxidants, or reducing agents.
An antioxidant will destroy free radicals by providing the extra electron, or chemically, a negatively charged hydrogen ion. This occurs practically instantaneously, in microseconds in fact, as soon as the free radical is formed, so you need a good supply of antioxidants in your body at all times. Free radicals do not roam your bloodstream looking for likely candidate cells to destroy – they do it right away with the nearest available, so antioxidants must be present at the time that the free radicals are created.
Other beneficial effects of such antioxidants are an increase in the potential for the mitochondria to generate energy within your cells, an increase in the hydration of body cells and a decrease in lactic acid build–up that occurs as the result of exercise. The negative charges of silica hydride atoms are very strong antioxidants and can Dramatically increase the energy production of mitochondria. It has been shown to do so by up to six times in Chinese hamsters. There is more on this claim for such a significant effect on your energy production later.
In addition to its action as an antioxidant, silica hydride is an electron donor to other antioxidants that have been neutralized by reaction with a free radical. When antioxidants do their work they are not destroyed, but neutralized. They act by giving an electron to the free radical, and are then one electron deficient themselves. This could virtually turn them into free radicals also were it not for the other electron donors available. Silica hydride is one of these. Thus, Coenzyme Q10, another very powerful antioxidant, can have is potency regenerated by silica hydride. If you take a silica hydride supplement, you are not only taking an effective antioxidant, but also a substance that can recharge the batteries of other powerful antioxidants.
Another side effect of this substance is that the reacted hydrogen atoms can also be used in the body to maintain a slightly alkaline pH which is an additional health benefit. pH is a measure of the acidity and alkalinity of the body fluids, and should be maintained slightly alkaline, other than in the stomach where the digestive juices are strongly acidic.
Silica hydride is not essential to the body, so you cannot suffer from a deficiency of it. It is not known to be contained in any foodstuff or water source, and appears to be available only as a supplement. Consequently no optimum dosage has been determined, though the supplements available contain from 200 to 250 mg per capsule. Likewise, side effects from it are unknown since there have been few scientific studies carried out on it. It has, however, been described as the ‘perfect antioxidant’.
Some of the claims made for the substance include reducing lactic acid concentration during exercise. Lactic acid production during exercise causes tiredness and cramps, and silica hydride is said to increase the body’s production of adenosine triphosphate (ATP) a substance essential for the production of energy in your body. This is through the reduction of nicotinamide adenine dinucleotide (NAD) to the reduced form NADH as a part of glycolysis and the citric acid cycle. Glycolysis is the metabolism of glucose to energy by the mitochondria.
If the claim that silica hydride effects this reduction of NAD to NADH six or seven times stronger than normal were true, then it would indeed be a significant energy booster invaluable to most athletes.
Passing on the Peptides: The Rise of Gluten-Free Diet And Fiber
January 02, 2008 03:22 PM
When going down the isles of any health food store, you'll find more and more cereals, breads, crackers, desserts, and supplements that claim to be gluten-free. Gluten refers to the peptides in wheat, rye, and barley that are problematic for gluten-sensitive individuals and cause great amounts of damage to the small intestine of those with celiac disease. About two million people in the US have celiac disease, and possibly more that have yet to be diagnosed. Gluten-free foods can help people with celiac disease, as well as many other conditions, feel better. There is currently no FDA regulation that defines the term "gluten-free" in labeling of foods, as long as the claim is not misleading.
Many companies currently provide an extensive selection of gluten-free supplements so that they can meet the needs of gluten-free living. For those consumers desiring a daily multivitamin/mineral supplement, there are large varieties available from many different manufacturers. Many manufacturers are trying to create a product that is able to support the digestion of gluten. They want the peptide to be broken down so that its individual amino acid will no longer damage the gut or create food sensitivities.
Supplemental digestive enzymes have been shown to give an increased advantaged to those who use a gluten-free diet along with enzymes. The Salba seed was recently introduced to those suffering from any level of gluten intolerance as a good source of fiber. It is the perfect solution because it is extremely high in fiber content for every serving and is a whole food source of fiber, which makes it better for you than a supplement that is manufactured solely to deliver fiber. Salba can be purchased as a seed and ground and pure cold-pressed oil. Because the vast majority of gluten-free foods that are available today are manufactured for great taste instead of nutrition, Salba is a great solution because it can be incorporated into gluten-free foods. Therefore, adding all the nutrition that is lacking in the products themselves, without adding any taste. Salba is also assimilated into the body easily because it is a whole food.
By not labeling the absence or presence of gluten on products, retailers and consumers are greatly challenged. Although wheat is one of the major gluten-containing grains, it’s important to remember that rye, barley, and other grains are also a source of gluten. Retailers are able to help consumers determine which supplements are gluten-free by being more knowledgeable about ingredients containing gluten that are included in dietary supplements. For example, grains are used in the processing of many ingredients, so it is often necessary to seek out the hidden gluten. Among those ingredients that should be avoided by consumers seeking gluten-free products are modified starch, vegetable gum, and caramel. Gluten-intolerant consumers often deal with the issue of managing their own health while being around those who do not have to handle gluten-intolerant issues. Due to Salba’s neutral taste and ease of use, it is the perfect solution of gluten-free and non gluten-free members who are found in the same household and eating the same foods. Salba can help the whole family to improve their health Dramatically.
Turmeric and Alzheimer’s Disease
May 10, 2007 12:38 PM
Turmeric and Alzheimer’s Disease
Compare these findings to people over the age of 65 living in the
So what are people who are living in
Q. How can curry prevent these changes in the brain? Isn’t that a lot to expect from a spice?
A. Evidently, it’s not too much to expect from this spice. Curry comes from the turmeric plant – Curcuma longa is the plant’s official name. Curcumin, a plant compound in turmeric, is the source of curry’s instantly recognizable bright yellow pigment. When it comes to the scientific research of Curcuma longa, the terms curcumin and turmeric are both used. Both refer to the same thing- tumeric extract.
There have been more than 1300 studies on tumeric and its health benefits for humans. Research has shown tumeric is able to help the body get rid of cancer-causing toxins. Turmeric also blocks estrogen receptors and enzymes that promote cancer. And it’s been found to stop the growth of new blood vessels in cancerous tumors – an important factor in keeping cancer from getting larger and spreading throughout the body.
But one of turmeric’s most exciting health benefits is its ability to reduce, prevent, and stop inflammation. While inflammation is a normal and needed response to injury or disease, chronic inflammation can cause damage to tissues. And researchers are now finding inflammation plays a huge role in Alzheimer’s disease.
Q. I’ve always heard that Alzheimer’s disease was caused by complex growths in the brain called plaques and tangles. How can simple inflammation cause such a devastating disease?
A. You are right. Plaques and tangles are indeed the hallmarks of Alzheimer’s disease. But researchers looking at the brain damage caused by Alzheimer’s have always noted the presence of inflammation wherever plaques and tangles form. In the past, this inflammation was thought to be simply a consequence of Alzheimer’s disease. Now scientists believe the inflammation itself starts a chain reaction ultimately contributing to the development of Alzheimer’s disease.
` When cells in the brain are disrupted by inflammation, amyloid, and a protein normally found in the brain, beings to act chaotically. This chaos results in the creation of beta-amyloid, protein that is toxic to cells in the brain. Sticky deposits of beta0amyloid build up and collect around the cells, making dense clumps or plaques. Because the brain can’t break the plaques down and get rid of them, they stay right where they are and slowly accumulate.
Tangles result when long protein fibers that act like scaffolding for brain cells begin to twist and tangle. The cell is damaged and eventually dies. But the tangled proteins remain in the brain even after the dead neuron has been cleared away. And inflammation might be the culprit causing the long protein fibers to start tangling.
The consequence of these abnormalities of protein in the brain is more than the cell death they cause. They also act as roadblocks interfering with electrochemical messengers being shot from cell to cell. Therefore, the remaining healthy cells’ activity is diminished as well.
Research of identical twins has repeatedly shown that if one twin has Alzheimer’s disease, the other has a 60% chance of developing the disease, too. Scientists from the Karolinska Institute in
In fact, the inflammatory process might occur years before the onset of Alzheimer’s, and be the result of any number of infections people can contract. That’s why current research is searching for ways to protect brain cells from inflammation. And why some countries have low rates of Alzheimer’s disease, like
Q. Why curry? Couldn’t other lifestyle difference account for the low rates of Alzheimer’s disease in
A. That’s a good question. When researchers begin studying a disease, like Alzheimer’s, they look for trends to help them determine how and why the disease occurs. For example, we all now know the connection between cigarettes smoking and long cancer. But, it wasn’t until the 1930’s that doctors noticed the trend fro cigarette smokers to have more lung cancer than people who didn’t smoke.
So it has been with researchers studying Alzheimer’s disease. They know Alzheimer’s disease has an important connection to inflammation. They also know turmeric reduces inflammation. And when researchers noticed these trends – that people in India eat high amounts of curry from turmeric and have very little Alzheimer’s disease – they began to theorize that turmeric might be able to prevent or even treat the illness. And the research they designed around these trends has unequivocally found turmeric to be on common denominator.
Q. What have the turmeric studies shown so far?
A. Simply amazing findings are coming from curry research. Not only does turmeric slow down cancer growth, it’s also been found to correct the cystic fibrosis defect in mice, help prevent the onset of alcoholic liver disease, and may slow down other serious brain diseases like multiple sclerosis.
Researchers from the
And now the UCLA Alzheimer’s Disease Research Center (ADRC) is using turmeric in clinical trials and studying the effect of this powerful spice in patients diagnosed with this devastating disease. Clinical trials are the gold standard of medical research. But it’s rare in Alzheimer’s disease. And it’s even more rare when all-natural herbs and spices like turmeric are used in hopes the positive benefits will be discovered. The head of the UCLA’s research team was recently interviewed and stated that setting out to hopefully prove turmeric’s ability to prevent and treat Alzheimer’s disease was “tremendously exciting.”
Q. I recently read that one of the non-steroidal anti-inflammatory drugs (NSAID) was found to prevent Alzheimer’s disease. Is this true?
A. Scientists recently studied ibuprofen, one of the NSAIDs investigated for Alzheimer’s disease Prevention. Ibuprofen belongs to a family of drugs that includes naproxen, indomethacin, nabumetone, and several others. These drugs are used most often to get rid of headaches, mild arthritis, and other kinds of pain and inflammation.
In the studies, the average dose of ibuprofen was 800mg a day. Patients took the product for two years. While the results suggested that ibuprofen might reduce the risk of developing Alzheimer’s, ibuprofen’s side effects are too harmful to be a valid lifelong prevent aid treatment. Ibuprofen, like other NSAIDs, can cause gastrointestinal bleeding when used at high dosages over a long period of time. Long term use of ibuprofen can also lead to analgesic nephropathy, a kind of kidney damage caused by NSAIDs.
As we discussed earlier, turmeric appears to block and break up brain plaques that cause the disease and helps reverse some of the damage already present. Ibuprofen does not provide any protection against free radical damage. No anti-inflammatory medicine can do this.
Q. If I eat curry will I be protected against Alzheimer’s disease? There aren’t many foods or recipes I make that require curry, do I need to eat it every day? And how much do I need?
A. If you enjoy Indian cuisine, by all means, enjoy these delicious foods. You’ll benefit your brain and your appetite. But you make a good point, American meals rarely contain curry. That’s why supplements that contain extracts are suddenly quite popular. In fact, there are numerous turmeric/curcumin supplements on the market today.
But like all nutritional supplements, some turmeric supplements are superior to others. You need to read their labels to make sure the turmeric extract you are buying will provide the protection you need. Look for high-potency turmeric extract from turmeric (Curcuma longa) rhizome. And make sure the extract is standardized to contain 90% curcuminoids, the active ingredient in turmeric responsible for the positive research findings.
Researchers once thought that preventing for Alzheimer’s disease would elude them for decades. In fact, several scientists privately speculated the disease might never be ameliorated. They thought the origin of the disease was too complex and the symptoms of the disease were too profound.
That’s why ongoing research on turmeric is so exciting. A safe, natural, and effective way to protect against Alzheimer’s disease almost seems too good to be true. But, the nation of
Memory And Focus
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased Dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a Dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
Safe Solutions for Chronic Pain
March 30, 2007 12:09 PM
Safe Solutions for Chronic Pain
One of the biggest challenged in healthcare today is the problem of pain. There are simply too many people living each and every day with ongoing, unremitting chronic pain. And there are far too many healthcare providers who – for a variety of reasons – are failing to adequately address this serious problem.
Recently, 368 doctors who routinely care for patients with chronic pain agreed to take part in a unique study. The doctors were surveyed about the pain medicines hey prescribe, what kind of treatment goals they hope to achieve, and how they felt about their ability to help their patients. They were also presented with four chronic pain vignettes or mock case studies and asked to select the best treatment for each scenario from multiple choice answers.
Sadly, many doctors chose the worst treatment options in the case studies. The medications they reported using in their practices did not reflect current pain treatment standards. They tended to set low treatment goals 0 instead of aiming for a least a 75% reduction of pain for their patients, they settled for 10% to 20% reductions. And many of the doctors admitted they lacked confidence in their ability to relieve their patients’ pain and suffering.
Adding to the challenge are the almost daily news announcements about dangerous side effects in certain pain medications. Synthetic prescription COX-2 inhibitors, once hailed as the safest of drugs, have been linked to heart attacks, strokes, blood clots, and intestinal bleeding. The over-the counter (OTC) drugs aspirin and ibuprofen kill over 16,000 people each year. And acetaminophen, the most widely used pain reducer in the
As a doctor specializing in chronic pain disorders, I know that optimal pain management can be a real challenge. However, I also know:
-You do not have to live in chronic pain.
-Your chronic pain, no matter what the cause, can be reduced, and usually
-Chronic pain can be relived both effectively and safely with powerful all-natural
Q. What is chronic pain?
A. Sudden, or acute, pain occurs when pain signals immediately fire in your nervous system alerting you to an injury, like a broken ankle, or an illness, such as appendicitis. Once the injury heals or the illness is cured, the transmission of pain signals stop.
Ongoing – or chronic pain – is much different. Chronic pain persists. Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial injury, such as sprained back muscles, or an initial illness, such as a serious infection. There might be an ongoing cause of pain, such as arthritis, cancer, or fibromyalgia. Chronic pain also occurs without any past injury or evidence of body damage.
The most common kinds of chronic pain are headache, low back pain, cancer pain, arthritis pain, and neurogenic pain (pain resulting from damage to nerves or to the nervous system itself). While chronic pain differs in its origin and where it occurs, it is generally your body’s way of saying that something urgently needs attention, and will not o away unless its underlying causes are addressed.
These causes can usually be determined if you remember the acronym “SHIN”. This stands for Sleep, Hormonal deficiencies, Infections/Inflammation/Impingement, and Nutritional deficiencies. When these are treated, pain often resolves.
Q. Why is it so hard to effectively reduce chronic pain?
A. Unfortunately, many physicians’ entire education in pain management consists of “giving nonsteroidal anti-inflammatory drugs or NSAIDs (pronounced en-sayds), COX-2 inhibitors, or acetaminophen and considering narcotics if the patient has cancer.
Some NSAIDs, like aspirin and ibuprofen, are available over-the-counter, while others, like the synthetic COX-2 inhibitors are only available with a doctor’s prescription. These mediations are usually inadequate and often toxic when used for chronic pain. And they do not address the problem(s) that the pain is trying to alert you to.
Q. What exactly are COX-2 inhibitors?
A. COX-2 inhibitors do pretty much what their name implies – they inhibit a natural enzyme in our body called the clclooxygenase-2, or COX-2, enzyme. There are two COX enzymes – COX-1 and COX-2 and both complete several actions in our bodies. One very important action that both COX-1 and COX-2 enzymes share is the speeding up of our body’s production of prostaglandins. These hormone-like substances are made by the cells of the body and have several important functions.
Some of the most powerful prostaglandins cause inflammation, pain, and fever when we are sick or injured. Prostaglandins also protect the lining of the stomach from the damaging effects of acid. Other prostaglandins make sure our platelets (important blood cells) make blood clots when needed. Still others help our kidneys get rid of unwanted salt and water. And researchers have just recently recognized the importance of still another prostaglandin that protects our heart and blood vessels.
The NSAIDs reduce pain by reducing prostaglandin production by blocking or inhibiting the COX enzymes. In theory – less prostaglandins, less pain and welling seems reasonable. But if you really stop and think about it, it’s pretty easy to understand why this method of pain relief might result in significant consequences.
Pain and inflammation are often needed for healing. And just as needed is the protection of our stomach lining, blood clotting ability, assisting kidney function, and keeping our blood vessels healthy. And scientists are beginning to understand if you interfere with one natural response, you may be disrupting the body’s ability to prevent extremes and imbalances.
That’s why using aspirin and ibuprofen can result in stomach ulcers, kidney problems, and internal bleeding. And that’s why using synthetic COX-2 inhibitors can result in high blood pressure, blood clots, heart attacks, and strokes.
Q. Why are we just now learning about the dangers of COX-2 inhibitors and other NSAIDs?
A. That’s a good question!
Many people over the age of 65 have chronic pain conditions and are frequent users of OTC and prescription NSAIDs. This age group also experiences heart disease and Alzheimer’s disease in greater numbers. So, if a 70 year old woman who’s been using Celebrex for the past two years for arthritis in her knees suddenly has a heart attack one morning, it would not be entirely unexpected.
For the past five or six years, researchers have been studying the possibility that NSAIDs may prevent certain cancers, Alzheimer’s disease, and other health problems. The ongoing, close scrutiny of large group of people taking these medications by scientists who were conducting these studies has resulted in the discovery of these dangers.
Q. What kind of natural compounds relieve chronic pain?
A. There are many – glucosamine, Omega-3 fatty acids, the B vitamins – the list goes on and on. Instead of disrupting normal bodily responses, these natural compounds work in harmony with our body to eliminate chronic pain. Three very powerful and very effective all natural plant compound pain and inflammation relievers are Sweet Cherry, Boswellia serrata, and White Willow Bark.
For many years there have been anecdotal or personal reports that claimed eating Sweet Cherries, specifically Prunus avium, wipes out back pain, arthritis, and gout. While anecdotal reports generally don’t account for much in the world of science, he sheer numbers of testimonials proclaiming the Sweet Cherry’s amazing ability to reduce pain made researchers sit up and take notice.
When Sweet Cherries were examined in the lab, it was easy for scientists to understand how this natural fruit is able to relieve pain. It seems Sweet Cherry’s bright red color is the key. Like many deeply colored fruits, Sweet Cherries are full of flavonoids called anthocyanins and proanthocyanidins.
These powerful plant compounds scavenge and destroy altered oxygen compounds called free radicals. Many degenerative, chronic diseases have been associated with the tissue damage caused by free radicals, including arthritis, heart disease, peripheral artery disease, and cancer. Cherry fruit extract is a natural anti-inflammatory compound, making it an excellent treatment for arthritis, fibromyalgia, and other chronic pain and inflammation diseases.
A pain relieving plant compound that comes from the bark of a tree, Boswellia serrata has been used by Indian healers for hundreds of years to reduce painful inflammation. When 20th century researchers looked at extracts of Boswellia Gum Resin in the laboratory they discovered the presence of powerful plant compounds, called boswellic acids.
Researchers found Boswellic Acids reduce inflammation in several ways. They open constricted blood vessels, improving blood flow to joints. They balance levels of leukotrienes – specific chemicals in the body that cause inflammation. And Boswellic Acids block two inflammatory chemicals that increase in asthma and inflammation of the colon. In addition to being helpful in treating these 2 illnesses, Boswellia has also been clinically studied and found to be quite effective in osteoarthritis and rheumatoid arthritis without any evidence of ulcers or stomach irritation.
Another bark extract, White Willow Bark is one of the oldest and most effective pain relievers. For over 2,000 years extracts from the bark of the White Willow tree have been used to ease aches and pains and reduce fevers. It is the original source of aspirin, but when used as the entire plant medicine, White Willow Bark is much safer than aspirin and quite effective.
White Willow Bark’s active ingredient is salicin and the combination of other compounds in the bark significantly enhances its pain killing power. In two large clinical trials of patients with chronic low back pain. White Willow Bark was found to be not only safer and much more effective than standard prescription therapies, it was also 40 percent more cost effective.
Salicylic acid from White Willow Bark lowers the body’s levels of prostaglandins, easing both acute and chronic pain. White Willow Bark reduces the pain and swelling of arthritis, headache, back and neck pain, muscle aches, and menstrual cramps. But, unlike aspirin, it doesn’t cause stomach bleeding or other known adverse effects.
Q. Do Sweet Cherry, Boswellic Acids, and White
A. They do indeed. Because they reduce both pain and inflammation by a broad combination of actions, these natural extracts have been proven to be excellent against arthritis, back pain, and pain from inflammatory intestinal diseases (Crohn’s disease and ulcerative colitis), and would be expected to be helpful in most kinds of pain.
Sweet Cherry, Boswellic Acids, and White Willow Bark relieve inflammation without causing stomach irritation, stomach ulcers, high blood pressure, blood clots, heart attacks, or strokes. That’s because these natural pain killers don’t disrupt the balance of enzymes or interfere with the body’s ability to prevent extremes and imbalances.
However, as with any pain therapy, Sweet Cherry, Boswellic Acids, and White Willow Bark work best when they are used as part of a comprehensive treatment plan to relieve the most common underlying causes of chronic pain or SHIN.
In addition, although these excellent natural remedies can often offer quick pain relief, natural remedies for severe chronic pains work best when they are given at maximum allowed doses and given 6 weeks to show their full effectiveness in combination with treating the pain’s underlying causes. The best chronic pain relief results when doctors and patients work together to meet the goals of treatment.
Some important last notes: Many causes of chronic pain are serious and life threatening. Everyone who is living with chronic pain must consult their doctor or other healthcare practitioner to determine the reason for their ongoing discomfort. In other words – make sure you know why you are having chronic pain and what’s causing the pain you want to relieve.
There are some types of chronic pain that only respond to opioids, or narcotic pain relievers. Morphine sulfate is an excellent pain medication and is used to relieve surgical pain, the pain of heart attacks, and pain from serious injuries. Morphine is also the very best drug for chronic cancer pain and non-malignant chronic pain. While many people fear opioids, these powerful pain killers can Dramatically improve quality of life. If you are suffering with chronic cancer pain and you are hesitant to use morphine or another opioid, I urge you to discuss your concerns with your doctor other healthcare provider. No one with cancer should live with untreated or under-treated pain.
Even chronic pain can often be eliminated when SHIN is in combination with powerfully effective natural pain relievers. But, because some people may need to take pain relievers the rest of their lives, the medications they use must be safe as well as effective. The very safest come from natural plant compounds that have been studied for their ability to relieve chronic pain. You can become pain free and Sweet Cherries, Boswellic Acids, and White Willow Bark can help.
CoQ10 for Heart Health
March 28, 2007 12:39 PM
CoQ10 for Heart Health
More than 40% of all deaths in the
One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health Dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. For what health conditions is CoQ10 used?
A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.
Q. Why is CoQ10 especially important to heart health?
A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.
Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.
Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.
In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.
Q. What studies support this fact?
A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?
A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.
The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.
Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?
A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.
While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?
A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:
1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.
2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.
3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at
4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.
Q. How much CoQ10 should I take?
A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.
CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What are some other heart-friendly supplements?
A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.
Q. What supplements support healthy blood pressure and cholesterol?
A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.
CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.
The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.
Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.
Supplements good for reducing stress and boosting energy!
March 26, 2007 02:05 PM
More and more Americans are feeling overworked, overtired, and overcome by life’s demands. We just do not have the energy we need to meet our responsibilities to the people we care about. More importantly, we don’t even have the energy to have fun! It seems that a constant feeling of fatigue has become part of the American way of life.
Research has shown that the same processes that cause lack of energy can rob us of sleep, saddle us with excess weight, disrupt our hormonal balance, and create significant amounts of stress in our daily lives. Chronic stress can Dramatically contribute to fatigue, sleep disorders, irritability, and anxiety. The research simply confirms what most of us already know – uncomfortable stress can really wear us out mentally and physically! It can take away the satisfaction of a job well done. It can take away our ability to believe in ourselves. And, sadly and maybe most importantly, continual stress can take the fun and joy out of life.
In a separate issue of Ask the Doctor, we discuss the energy and sleeping needs of people suffering from chronic fatigue syndrome and fibromyalgia. In this issue, I discuss the 3-step process I call “Vitality 101.” People do not have to accept pain, insomnia, or fatigue. It’s time for everyone to feel great and have a life they love!
Step 1 – Nutrition
Good overall nutrition is important for everyone! As a foundation product to support energy levels, a powdered drink mix is a pleasant, easy way to ensure that you are taking all of the necessary vitamins, minerals, and amino acids that you need to have great energy all through your day.
The following chart lists the most critical ingredients. You can see that almost all of the vitamins and minerals work together to help improve energy levels and overall health.
In addition to the powdered energy drink mix, it is important that you also take a high potency vitamin B-complex supplement. This should include niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, which are especially important to restore the energy production needs of your body. It is also critical to get enough water, as most Americans are chronically dehydrated.
Step 2 – Rest Your Body
Having trouble sleeping is one of the most troubling symptoms of stress. While the stress is wearing us down and making us tired, it’s also keeping us tense and unable tot relax. The result? That easy drift into sleep becomes harder and harder. And if we are lucky enough to actually get some shut-eye, stress will often wake us up, sometimes several times a night.
This occurs because excess stress suppresses the sleep center in the brain. It is important to break the “stress/insomnia cycle” early, before it results in pain and hormonal and immune dysfunction!
Because good quality sleep is how the body repairs and re-energizes itself, it may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Look for a supplement that has a blend of herbs that promote deep sleep, such as valerian, L-theanine, hops, passionflower,
Step 3 – Manage Excess Stress Levels
In this fast paced world, it is important to learn to manage the stressor in our lives. Glandular extracts, such as raw adrenal extract, can offer natural support to help our bodies deal with the effects of stress and, in turn, can boost your energy levels. Exercise is another stress buster. Using your body physically is important for good health. Find something that is fun for you, however, or you are unlikely to stick with it!
Q. Does stress zap my energy in any other ways besides making me lay awake at night and causing me to be a zombie the next morning?
A. Most people are familiar with the body’s Dramatic response to an emergency. The heart pounds, the muscles constrict, and the lungs expand – and while this is happening, we are capable of greater than normal strength and speed. This response is the body’s way of rescuing itself when faced with an emergency. We don’t have to think about it to make it happen. It’s automatic.
The same can be said of a chronic stress response. Whether we’re late for a business meeting because we’re stuck in traffic, or worrying about how we are going to pay for our children’s college tuition, our response to stress happens automatically. The difference between the two is that the body’s response in an emergency starts and resolves itself quickly. The response to being stuck in traffic may not.
The body makes the “stress hormone”, cortisol, to handle the normal stresses of day-to-day living. But in an emergency situation, the adrenal glands, located above the kidneys, secrete increased amounts of this hormone until the emergency passes. Then the body returns to its normal function. Unfortunately, however, chronic stress is more complex. When our body is subjected to increased amounts of the hormone, cortisol, for an extended time, it can lead to a condition known as “adrenal burnout” or “adrenal fatigue.” While it’s true that very large amounts of cortisol can have damaging effects on our hormones, too little cortisol doesn’t allow us to respond to stress properly. It’s really a matter of balance.
Q. How can I control the stress in my life and re-energize?
A. Many people who are under constant stress may have adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.
The good news is that changes in our hormone levels can return to normal when stress is decreased. The key in learning how to deal with daily stress is to allow the body to return to its normal state. I discuss additional techniques for coping with stress in my recent book Three Steps to Happiness! Healing Through Joy (see my website, www. jacobeitelbaum .com, for more information). In addition to stress control, it is important to supplement your adrenals with a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy, which uses the concentrated forms of bovine (cow) or porcine (pig) glands, can improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacked and thus repaired the malfunctioning gland.
If you are one of the unlucky folks with stressed-out adrenal glands, you should see great results from taking raw adrenal supplements. Be sure to buy adrenal extract supplement that contains both whole adrenal and cortex adrenal.
The best adrenal supplement should also contain vitamin C, vitamin B6, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.
Did your grandmother ever tell you to eat your liver so that you didn’t get “tired blood?” Well, it turns out that she was right. Liver extract is another glandular extract that can help improve energy levels.
Liver extract is an excellent source of highly bioavailable nutrients including iron, B vitamins (especially B12), and other minerals. The stamina and energy-enhancing benefits of liver are widely touted. Liver extract has been shown to support healthy function of the liver and increase the energy levels inside our body.
Because heat will destroy the key components in the liver, a high quality liver extract supplement should be cold-processed and encapsulated to enhance speed and absorption of nutrients from liver. A high quality aqueous liver extract supplement should also contain vitamin B12 to support healthy blood iron and oxygen levels to energize.
Q. It will be great to get a good night’s sleep. Are there also any other natural alternatives that could help promote relaxation and increase my energy levels during the day?
A. Yes, there are. Rhodiola rosea is an all-natural herb that has long been used to help relieve stress and increase energy. Rhodiola has also been used to lift our moods, improve sexual satisfaction, and even help in certain nervous system disorders. First used in Siberia and
In clinical trials, the most effective Rhodiola rosea extract was found to contain 3% rosavins and 1% salidroside. While there are many Rhodiola supplements in health food stores, only those containing these specific amounts can provide the best results.
Altered digestion, food intolerances, decreased energy, fatigue, cognitive problems, and sleeplessness create the need for changes in daily living routines. These can include alterations in diet; exercise modifications; alterations in activities of daily living according to one’s energy level; and sleep/rest management. All may require the assistance of a professional clinician, such as a chiropractor, nutrition specialist, physical and/or occupational therapist, mental health professional, or sleep therapist.
Super busy lives demand super strength nutrition. Begin each day with a powdered nutritional supplement after getting at least 8 hours of sleep each night. In addition to the nutritional beverage mix, a vitamin B complex supplement should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients to combat your fatigue. Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Rhodiola rosea, and ginseng can offer additional natural nutritional support in your busy life to boost your energy levels. These nutritional supplements can be used daily and you will feel energized to get through each day’s challenges and opportunities!
March 08, 2007 12:27 PM
Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.
Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.
To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.
Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.
Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.
Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.
In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."
In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:
• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.
• 78.9% of subjects showed an increased mean value of hair diameter.
• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."
Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.
Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:
• Total Number of Hairs: Significantly Increased
• Total Number of Terminal Hairs: Significantly Greater
• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher
• Hair Follicle Activation: Intensive
In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.
Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.
Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.
The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.
Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.
Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.
Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.
Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.
Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.
If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.
Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.
The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.
Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.
After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.
Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.
MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.
The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.
MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.
Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.
The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.
According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.
The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.
Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.
Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.
The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.
Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.
Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.
Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.
L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.
The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.
Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.
In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.
Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.
Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.
Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.
Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.
After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.
This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.
Q. Is Revita safe ?
A. Revita primarily contains compounds that are not only safe in topical use, but actually Dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.
Q: Can I use hair sprays, mousses, gels, etc.?
A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.
Q: Can I have my hair colored or permed while using Revita ?
A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.
Q: What is SLS/SLES free ?
A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.
Q: Can I blow dry my hair after using Revita ?
A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.
Q: Who is a candidate for Revita ?
A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.
Q: What type of results should I expect with Revita ?
A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.
Q. Does Revita have any systemic side effects ?
A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.
Q. Does Revita work for women?
A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.
Q. I am using other topical treatments. Can I use Revita at the same time ?
A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.
Q. Do I need to use Revita for a long time ?
A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.
Q: Is stress a factor in hair loss?
A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.
Chronic Fatigue Syndrome and Fibromyalgia
February 28, 2007 12:02 PM
This is a fast paced world. We are all busy; living our full lives, burning the candle at both ends. We all get tired. We all get sick from time to time and maybe even depressed. But the illness called chronic fatigue syndrome is not like the normal ups and downs that we experience in everyday life. People with chronic fatigue syndrome feel overwhelming fatigue, and often pain as well. This is an illness that does not go away with a few good nights’ sleep. It drags on and on and doesn’t resolve itself. It steals vigor and energy over months, and sometimes even years.
In this issue of Ask the Doctor, we will talk about powerful vitamins, minerals, amino acids, and herbs combined in scientifically validated formulas that people with chronic fatigue syndrome or fibromyalgia can use every day. These nutrients help address some root problems of chronic fatigue syndrome and fibromyalgia by restoring energy and health to sufferers.
Q. What is chronic fatigue syndrome?
A. Chronic fatigue syndrome (CFS) also known as chronic fatigue and immune dysfunction syndrome (CFIDS), or myalgic encephalomyelitis (ME), is a group of symptoms associated with unrelenting and debilitating fatigue. The profound weakness of CFS causes a persistent and substantial reduction in activity level. You feel too tired to do normal activities or are easily exhausted for no apparent reason.
Besides extreme fatigue, symptoms of CFS include general pain, mental fogginess, flu-like symptoms, and gastrointestinal problems. A list of symptoms includes:
The number of symptoms and the severity of these symptoms can vary among people. The symptoms of CFS hand on or reoccur frequently for more than six months.
Q. Are chronic fatigue syndrome and fibromyalgia considered being the same illness?
A. Fibromyalgia syndrome (FMS) is a painful shortening of muscles throughout the body. FMS is basically a sleep disorder characterized by many tender knots in the muscles. These tender knots, called tender or trigger points, are a major cause of the achiness that people with fibromyalgia and CFS feel.
Approximately 80 percent of chronic fatigue syndrome patients have received and overlapping diagnosis of fibromyalgia syndrome. For most people, fibromyalgia and chronic fatigue syndrome are the same illness.
Q. What causes chronic fatigue syndrome?
A. There are many causes that can trigger CFS. Current research is looking at the roles of neuroendocrine dysfunction, viruses, environmental toxins, genetic predisposition, food sensitivities, yeast overgrowth, faulty digestion, or a combination of these factors.
For many people, CFS is triggered by a bout with a viral illness (like a cold or the flu), or even a stressful event. CFS is usually a mix of underlying causes. It is like a domino effect in that each problem can trigger another problem, and so on. For example, fatigue and poor sleep can trigger a weakened immune system, which can, in turn, trigger yeast or bacterial infections.
Q. Who gets chronic fatigue syndrome?
A. CFS is more common than you might expect. It strikes people of all ages, racial, ethnic, and socioeconomic groups. Approximately 800,000 people nationwide have CFS and over six million have fibromyalgia at any given time.
It is important to stress that CFS is a real illness; it is not “just in your head.” Unfortunately, sufferers of CFS may find that many healthcare practitioners discount the symptoms of this illness or misdiagnose it as another disease. This can lead to additional emotional suffering.
Q. How long does chronic fatigue syndrome last?
A. The illness varies greatly in its duration. Some people recover after a year or two. More often, those who recover are more likely to do so three to five years after onset. Yet for some people, the illness seems to simply persist. There are rare cases of spontaneous improvement after five years without undergoing any treatment. However, this is very unusual.
Q. What are the complications of chronic fatigue syndrome?
A. The patterns of CFS vary from individual to individual. However, many common patterns of symptoms are seen in CFS sufferers. These symptoms and problems interact and create new symptoms and problems. For example, infections and disrupted sleep can lead to digestive, hormone, and immune problems.
The most notorious pattern seen in CFS is the one in which a person suddenly comes down with a flu-like illness that doesn’t go away. These viral or bacterial infections can suppress the body’s master gland, the hypothalamus. Since the hypothalamus controls the other glands, including the adrenals, ovaries, testes, and thyroid, suppression of this gland will lead to a subtle but debilitating decrease in the functioning of all glands and their hormones. Suppressed hypothalamic function from chronic infections can then trigger sleep dysfunction.
The suppression of the hypothalamus gland can lead to poor sleep because the body confuses its day/night cycles. Because of this, people with CFS have trouble staying in the deep, restorative stages of sleep that “recharge their batteries.”
Poor sleep can cause immune suppression, which may lead to secondary bowel infections. The bowel infections seen in people with CFS can cause decreased absorption of nutrients, which can lead to chronic vitamin and mineral deficiencies.
Q. Is there a cure for chronic fatigue syndrome?
A. Treating chronic fatigue syndrome presents a significant challenge to people with CFS and their healthcare practitioners. Recently, a published placebo-controlled study ( of which I was the lead investigator) showed that when using an integrated treatment approach, over 85 percent of CFS and fibromyalgia patients can improve, often Dramatically. The full text of this study can be seen at ‘www.endfatigue.com’. An editorial in the April 2002 issue of the Journal of the American Academy of Pain Management noted that this treatment, which I developed, is now a highly effective and excellent part of the standard of practice for treatment of fibromyalgia. Since this treatment addresses many different problems associated with CFS/FMS, it needs to be individualized to each patient.
Medications that provide symptom relief are frequently the first line of treatment chosen by healthcare practitioners for the person with CFS. These include medications for pain, sleep disturbances; digestive problems such as nausea, depression and anxiety, and flu-like symptoms.
However, medications have not been universally successful because they tent to put a bandage on symptoms instead of addressing the root problems. Because of this, medications may need to be supplemented by the other supportive therapies that can address the root problems.
People with CFS/FMS may be depressed, given the catastrophic lifestyle disruption these diseases may cause. They may also feel guilt and frustration because their symptoms were not taken seriously for such a long time. Fear can be a factor as employment and family relationships may be jeopardized by this illness.
Therapies that help people to relax and improve coping skills may be helpful and include counseling for emotional and mental health, cognitive behavioral therapy, sleep management therapy, and massage.
Daily Nutritional Supplementation for Energy
Good overall nutrition is important for everyone, of course. However, there are several vitamins, minerals, and amino acids that can have powerful nutritional effects for a person with CFS. All of the vitamins and minerals in a chronic fatigue/fibromyalgia formula should work together synergistically to help improve energy levels and overall health. Here are some key nutrients to look for in an energy formula:
Vitamins, Minerals & Other Key Ingredients
Vitamin A: Essential for healthy skin and mucous membrane integrity, healthy immune system responses and healthy bone growth and healthy reproductive processes. Vitamin A in the form of beta-carotene is an antioxidant and free radical fighter. Vitamin E: Helps to relieve pain in CFS patients. Can also improve night leg cramps, which interferes with sleep.
Vitamin C: Enhances immune function by increasing natural killer cells, B and T cells. Can prevent chronic bladder infections by acidifying urine.
Vitamin D: Regulates immune functions of monocytes and neutrophils. Neutraphils are white blood cells that ingest invasive bacteria, and act as the first line of defense once bacteria makes it past the skin barrier.
Magnesium: Involved with immune support. Working with malic acid, enhances immune function by increasing natural killer cells. Magnesium is also critical for the relief of muscle pain.
Inositol: Enhances immune function by increasing natural killer cells.
Malic Acid: Working with magnesium, improves energy levels by improving cellular functions. Especially important in muscle metabolism.
Betaine: Works with B vitamins to synthesize amino acids, and acts as a precursor to SAM-e. SAM-e (S-adenosylmethionine) is a naturally-occurring molecule in the body, and may have an effect on overall mood elevation.
Amino Acids: Glycine, Serine, Taurine, Tyrosine are essential for the production of energy in the body. Also essential for brain function.
Zinc: Supports the immune system by enhancing neutrophils activity and supporting healthy antigen-antibody binding.
Selenium: Supports immune function by enhancing antibody production.
Fructooligosaccharides: Provides nutrition for good bacteria in the intestinal tract, improving digestion and healthy microflora.
All of the vitamins, minerals, and other nutritional supplements on the list are important to ensure recovery from chronic fatigue syndrome. To ensure that your nutritional supplement regimen contains all of these ingredients, look for a powdered supplement formulated specifically for CFS/FMS sufferers that can be reconstituted in a beverage of your choice. A powdered drink mix is a pleasant, easy way to ensure that you are taking all of the needed vitamins, minerals, and amino acids that will give you the needed energy to recover from your illness.
B Vitamin Complex for Energy
In addition to the powdered energy drink mix, it is important that you also take a vitamin B-complex supplement specifically formulated for people with CFS/FMS. The B vitamin formula, which should include niacinamide, thiamin, riboflavin, vitamin B6, folic acid, vitamin B12, pantothenic acid, and choline, is especially important to restore the energy production needs of your body, as well as for mental function. It is also important to make sure that the dosages are high enough CFS/FMS needs. The chart in the next column lists the B vitamins that are critical for people suffering from CFS/FMS.
B Vitamins Effect on Chronic Fatigue Syndrome
Studies have demonstrated that people with CFS/FMS are often deficient in many of the B vitamins, which tends to worsen their symptoms of fatigue and mental “fogginess” and ultimately lead to a weakened immune system.
B vitamins - Effect on Energy
Thiamine (B1) - Essential in the process of energy production. This vitamin also removes lactic acid from muscles, which causes them to be sore in fibromyalgia patients.
Riboflavin (B2) - Riboflavin (vitamin B2) is crucial in the production of body energy. Supports healthy gluthathione reductase activity, which helps maintain gluthathione, a major protector against free radical damage. Vitamin B2 itself also has antioxidant qualities.
Niacinamide(B3) - Essential vitamin that is a component of the body’s energy furnace, helping to improve fatigue and “brain fog”.
Pantothenic Acid (B5) - This vitamin improves adrenal gland function, which will boost energy levels. It can also aid in weight loss by decreasing appetite.
Vitamin B6 - Working along with thiamine, this vitamin is critical in the process of energy production.
Vitamin B12 - Important for brain function and nerve repair. Aids in relieving fatigue symptoms in CFS patients. Folic Acid - Aids in strengthening the immune system, and aids in mental clarity and concentration.
Q. What other supplements can help me with CFS?
A. Many people with CFS/FMS are suffering from adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress like that seen in cases of CFS. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.
The good news is that changes in our hormone levels can return to normal when stress is decreased. However, in cases of CFS that return to normal can be made much simpler by using a glandular therapy regimen to ensure healthy cortisol levels and adrenal function.
Glandular therapy uses the concentrated forms of bovine (cow) or porcine (pig) glands to improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacks and thus repairing the malfunctioning gland.
If CFS has left your adrenal glands in a stressed-out state, you should see great results by taking adrenal supplements. Be sure to buy an adrenal extract supplement that contains both whole adrenal and adrenal cortex extracts.
The best adrenal supplement should also contain vitamin C, vitamin B6, L-tyrosine, betaine, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.
The Road to Recovery-Adequate Sleep
Disordered sleep is the underlying process that drives many of the symptoms of CFS/FMS. The most effective way to eliminate pain in CFS/FMS is to get seven to nine hours of deep sleep each night.
However, getting adequate sleep is easier said than done for CFS sufferers with underlying fibromyalgia symptoms. The muscle knots of fibromyalgia make it uncomfortable to lie in one position for an extended time, causing difficulty in returning to deep sleep. Because of this, people with CFS/FMS do not stay in deep stages of sleep to recharge their “batteries.” In addition, poor sleep can cause and be caused by the suppression of the hypothalamus gland, which causes the brain to think it is daytime instead of night time.
It may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Therefore, it is important to look for an herbal sleep formula that is especially formulated for people with CFS/FMS. The combination of herbs is important as each herb addresses a different aspect of sleeplessness and muscle tension.
Ingredients - Effect on Sleep
Wild Lettuce - Has been found to have sedative effects.
Hops - Acts as mild sedative and has a sleep-inducing effect. Jamaica Dogwood Has been found to be mildly sedative and is often used for anxiousness.
L-Theanine - Causes significant increases of neurotransimitter concentrations in the brain, which promotes muscle relaxion and improves sleep.
Valerian - This herb has been clinically studied for its ability to improve sleep quality.
Passionflower - This herb eases nervousness and insomnia.
Putting It All Together
After a good night’s rest, a powdered energy drink mix formulated for people with CFS/FMS should be drunk along with a well-balanced breakfast as discussed earlier. In addition to the nutritional beverage mix, a vitamin B complex supplement designed specifically for CFS sufferers, also discussed earlier, containing niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients, to combat your overwhelming fatigue, pain, and “brain fog.” Taking a daily adrenal supplement, like the one discussed earlier, will provide the much-needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy.
Together, these four interventions: sleep formula; morning energy drink; energy B complex supplement; and an adrenal complex- can make an incredible difference that you should begin to notice within 2-3 weeks of starting this program.
Chronic fatigue syndrome and fibromyalgia are complex physical diseases with physical causes. The unrelenting symptoms of fatigue, pain, and mental fogginess can be overwhelming and frightening. Partnering with a healthcare practitioner specializing in CFS and utilizing different medical treatments, supportive therapies, and lifestyle changes are healthy ways to combat chronic fatigue syndrome. And taking nutritional supplements formulated specifically for people with CMS/FMS that help boost energy or help you get a good night’s sleep can give you critical control over the outcome of your illness and set you on the road to recovery.
Neurological Health and CoQ10
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.
Q. Isn’t CoQ10 a supplement for heart health?
A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite Dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.
Q. How does CoQ10 affect brain health?
A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.
The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.
The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.
Q. What is the blood-brain barrier and why is it important?
A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.
Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.
Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.
Q. If CoQ10 is made in the body, why take supplements?
A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.
Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.
Q. How does CoQ10 help people with Parkinson’s disease?
A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.
A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.
Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.
The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.
The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.
Q. What were the results of clinical research on Huntington’s Disease?
A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.
Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.
Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.
Q. What other diseases could benefit from CoQ10 supplementation?
A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.
In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.
ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.
Q. Can taking CoQ10 prevent neurodegenerative disease?
A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.
Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.
Q. How much CoQ10 should I take?
A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.
CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What should I look for in a CoQ10 supplement?
A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.
CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.
All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
For Better Heart Health ...
February 06, 2007 12:57 PM
Nutrients Every Heart Needs
High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the
Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.
In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.
Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?
A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.
A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.
Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.
Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.
Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.
Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.
Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?
A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.
Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?
A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.
That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,
Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.
Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.
Q. Don’t all multivitamins work with medications prescribed to treat heart disease?
A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.
The more risk factors you have, the greater your chance of developing heart disease.
Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?
A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.
The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.
The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.
Whole Heart Nutrition
Each additional risk factor requires additional supplements or increased doses for protection from heart disease.
Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.
A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.
In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and
Research has shown that the Omega-3 fatty acids in fish oil supplements can:
-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.
-Lower the levels of triglycerides, fats in the blood that can increase a person’s
risk of dying from a heart attack, even if a person’s cholesterol levels are normal.
-Slow atherosclerosis – the growth of harmful plaque on artery walls.
Atherosclerosis develops over many years. If the plaque growth is slow and
stable, chances are low that a heart attack will result. However, rapidly growing
or unstable plaques can rupture. The body responds with inflammation, which
causes blood clots to form. These blood clots block the artery and cause a heart
-Keep blood pressure levels low. Many people have high blood pressure for years
without knowing it. That’s because it has no symptoms. Uncontrolled high
blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.
While 25% of Americans have high blood pressure, nearly one-third of these
people don’t know they have it. This is why high blood pressure is often called
the “silent killer.”
You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.
However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.
Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. Rancid fish oil is not going to help your heart at all and may actually hurt it.
Q. That leaves CoQ10. Why is it important for Jane and Earl?
A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.
CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.
Q. How does CoQ10 actually work? Has it been studied in heart disease?
A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.
In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.
The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.
Q. What if I have already been diagnosed with Congestive Heart Failure? Will CoQ10 still help me?
A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.
In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.
Q. Are some types of CoQ10 better than others?
A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.
The best CoQ10 has to meet the following criteria:
1. Must be easily absorbed during the digestion process so that it can get into the
2. Must reach the mitochondria in the cell.
3. Must be proven effective in studies.
4. Must be safe and free of impurities.
Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?
A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.
Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.
Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”
Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.
Mushrooms are good for the Immune System
January 26, 2007 06:12 PM
Medicinal Mushrooms Grown on Purple Kculli Corn Yield Life Changing Results
Even though we treat them like vegetables, mushrooms aren’t really plants. They’re fungi and fungi grow much differently than fruits and vegetables. Most food plants, like strawberries, broccoli, and red bell peppers make chlorophyll from sunlight to gain the nutrients they need to grow. Mushrooms don’t make chlorophyll; to get the nutrients they need to grow, mushrooms release enzymes into the forest floor or flora they’re living on to break down the organic matter into a form the mushroom can absorb.
Because most mushrooms that we eat or use today are raised as crops, or cultivated, they are grown on a variety of substrates. Similar to the commercial potting soils you can buy at nurseries and garden stores, mushroom substrates vary widely in quality and the kinds of nutrients within. Mushrooms are really unique in that they can grow on almost anything, such as sawdust, shredded newspaper, and straw.
However, mushrooms are only as nutritious as the substrate they were grown on-even those unique varieties called medicinal mushrooms. While the simple button mushrooms found on pizza are most often eaten for their woodsy taste and texture, the use of medicinal mushrooms is much more complex. These mushrooms are valued because they contain numerous compounds that have been extensively studies by researchers for their ability to activate cells of the immune system.
Researchers have recently discovered that when medicinal mushrooms are grown on a Purple Kculli (pronounced ka-coo-lee) Corn substrate, the resulting mushrooms are jam-packed with powerful and potent disease-fighting compounds. Beautiful Purple Kculli Corn has long been used by the people of the Peruvian Andes as a tasty vegetable, natural food color, and powerful functional food-keeping them healthy and free of disease.
In this issue of Ask the Medicine Hunter, we’re going to talk about four powerful medicinal mushrooms that, when grown on Purple Kculli Corn, have even more potent compounds to prevent and treat cancer and other serious health problems.
Q. How exactly do medicinal mushrooms prevent and treat cancer?
A. Medicinal mushrooms are very complex. They contain numerous compounds that have been extensively studied for their ability to activate cells of the immune system. Some of the most amazing immune boosting compounds in medicinal mushrooms are beta-glucans 1-3, beta glucans 1-6, arabinogalactins, and arabinoxylans – compounds that work “hand-in-hand” with certain cells of the immune system. But to get abundant amounts of these compounds, medicinal mushrooms must be grown on substrates with high levels of nutrients. And the most nutrient dense substrate of all comes from Purple Kculli Corn.
Q. Why is Purple Kculli Corn extract good for growing medicinal mushrooms?
A. You’ve probably heard that brightly colored fruits and vegetables (like beets, broccoli, and blueberries), have more antioxidant power than paler fruits and vegetables (like iceberg lettuce, onions, and garlic). In fact, the deeper the color, the better. And there is no deeper color in nature than the deep purple of Purple Kculli Corn grown in the lush coastal plains of Peru. The kernels from Purple Kculli Corn are not only naturally beautiful, the pigment itself is extremely healthy and have been used by the people of the Peruvian Andes for centuries as both food and food coloring.
Once harvested, the Purple Kculli Corn is naturally processed into an antioxidant-rich extract. When certain medicinal mushrooms are grown on Purple Kculli Corn extract, the Purple Kculli Corn becomes a super-substrate, producing medicinal mushrooms with incredible amounts of the immune-boosting compounds. And when Purple Kculli Corn extract is added to medicinal mushroom formulas the antioxidant power increases, too.
Q. How do the medicinal mushroom compounds fight disease?
A. When bacteria, viruses, or other pathogens are present in the body, white blood cells, or leukocytes, swing into action. Leukocytes work together to defend the body against infections, like colds or the flu, as well as diseases that start within us, like cancer. These disease fighting cells are the backbone of the body’s defense system. And each type of cell works in different ways.
The macrophage, a name that means “big eater,” is a first-strike leukocyte that protects us from disease by, quit literally, devouring invading pathogens. Natural Killer (NK) cells act like sentries – constantly prowling for cancer cells, killing them quickly when they’re discovered. B-cells are the immune system’s military intelligence, seeking out targets and communicating their coordinates, while T-cells are the foot soldiers, destroying the invaders that the intelligence system has identified.
Scientists have long known that medicinal mushrooms help make white blood cells more deadly. But until recently, they weren’t sure how. Research has now shown that macrophages and NK cells have receptor sites specifically for beta-glucans 1-3 and beta-glucans 1-6. When the beta-glucans bind to the macrophages and NK cells, they make the lymphocytes stronger and more lethal. By increasing the lymphocytes’ strength, beta-glucans help them churn out more of the specialized chemical messengers, too.
Arabinogalactins and arabinoxylans, powerful polysaccharides found in medicinal mushrooms, are potent stimulators of the immune system. These compounds increase the activity of interleukins, interferons, and a tumor necrosis factor, all key components in a healthy immune system. When medicinal mushroom extracts with high amounts of Arabinogalactins and arabinoxylans are taken, diseases are Dramatically reduced.
Researchers found that complex polysaccharides in four varieties of medicinal mushrooms – Agaricus blazei (Agaricus), Grifola frondosa (Maitake), Coriolus versicolor (Coriolus or Turkey Tail), and Ganoderma lucidum (Reishi) – are serious cancer fighters. The chart below explains how:
Mushroom Health Benefit
Agaricus (Agaricus Blazei)
Agaricus not only contains the greatest number of medicinal compounds, it also contains a powerful anti-tumor polysaccharide that all other medicinal mushrooms are lacking. Recently, 100 women who were receiving carboplatin, a chemotherapy drug used to treat ovarian cancer, volunteered for an important study. Half of the women were given an extract of Agaricus mushrooms, while the other half were given a placebo or dummy pill. The researchers discovered that NK cell activity was significantly higher in the Agaricus group. The women in this group were also less nauseated, fatigued, and wear than the women taking the placebo, an important consideration for people with cancer.
Maitake (Grifola Frondosa)
Maitake is one of the most researched of all medicinal mushrooms. In one clinical study, the effect of Maitake mushroom compounds were studied in ten patients with cancer who were not currently taking any chemotherapeutic drugs. The researchers found that the Maitake not only significantly stimulated NK cell activity, it also repressed the cancer’s growth, and stopped the tumors’ ability to metastasize, or spread to other parts of the body. And in another clinical study, 165 patients with various types of advanced cancer were given Maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, 69% of breast cancer patients, and 62% of lung cancer patients. Plus, when Maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.
Versicolor compounds show great promise as cancer immunotherapy agents in all cancer stages. In one clinical trial, 34 patients with advanced terminal lung cancer were given Coriolus versicolor polysaccharides or a placebo (dummy pill) for 28 days. While the group getting the Versicolor felt less fatigued and sick, very important considerations at the end-of-life, there were no changes in the placebo group.
Reishi (Ganoderma Lucidum)
Reishi mushrooms are too tough to eat, but they’ve been used medicinally for centuries and have been extensively researched. In a safety study to determine Reishi’s effect on blood thinning mechanisms, healthy volunteers received 1.5 gm Reishi or placebo daily for 4 weeks. There were no significant changes in either group and all blood clotting measurements remained within the normal range, demonstrating its safety. In a recent clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.
Not only do Agaricus, Maitake, Coriolus, and Reishi have incredible amounts of immune boosting polysaccharides, when they are grown on Purple Kculli Corn, they also have a much higher ORAC value than mushrooms grown on other substrates.
Q. What are ORAC values?
A. ORAC, or Oxygen Radical Absorbance Capacity, is a measurement of the antioxidant power in fruits and vegetables. The higher the power, or ORAC value, the stronger the antioxidant is against free radicals. While free radicals are made by breathing oxygen and digesting food, and are simply the consequences of being alive, the older we get the more free radicals we make. And the more free radicals we make the more destructive they can be. Free radicals will rip membranes, wreck cells, cripple mitochondria, and ruin DNA. As this damage accumulates, even more free radicals are made. And if not stopped or slowed, this might lead to heart disease, arthritis, diabetes, dementia, and cancer.
Q. How does Purple Kculli Corn increase the ORAC value of medicinal mushrooms?
A. All brightly colored fruits and vegetables have very high ORAC values; and the higher the ORAC value – the greater the antioxidant power. Not only can we measure the ORAC values of fruits and vegetables, we can also measure the ORAC values of mushroom substrate extracts. Purple Kculli Corn extract has an ORAC value of 1789 (measured in umolesTE/gram). Now, remember that mushrooms are fungi, not fruits and vegetables, and they gain most of their nutrients from the ground (or substrate) they are grown on. When mushrooms are cultivated or “farmed” on substrates with a high ORAC value, they will absorb compounds from the substrate giving them a higher ORAC value, too. So growing mushrooms on antioxidant rich, high ORAC value, Purple Kculli Corn yields medicinal mushrooms with high ORAC values as well.
Q. Some mushroom supplements have more than four medicinal mushrooms. Wouldn’t a mushroom supplement with seven mushrooms or more have a higher ORAC value than a supplement with only four?
A. Well, more is not always better – especially when it comes to medicinal mushrooms. Some supplements have a “kitchen sink” selection of mushrooms. The makers of these supplements hope that by adding modest amounts of many mushrooms, they will end up with a product that just might have some health benefits.
Clearly, it’s not how many or how exotic the mushrooms are in a medicinal mushroom supplement, it’s the substrate that mushrooms are grown on that makes the difference.
Q. How can I make sure the medicinal mushroom supplement I buy contains natural and organic mushrooms grown on Purple Kculli Corn substrate?
A. Become a label reader! Medicinal mushroom formulas have a statement showing accreditation from a certifying agency, such as the American Food Safety Institute, International; California Organic Farmer Association, Minnesota; or Crop Improvement Association, on the label, and have met certain criteria. They must be grown without chemicals or pesticides. The growers must be certified as organic mushroom produces by an accredited third party. And the growers must keep a record of their production and handling practices.
Of the nearly 38,000 varieties of mushrooms, Agaricus blazei, Grifola frondosa, Coriolus versicolor, and Ganoderma lucidum have impressive medicinal properties. With a little help from Purple Kculli Corn, these mushrooms can provide even more potent and powerful cancer preventing properties for superior mushroom supplements.
Q. How did research discover maitake’s health benefits?
November 22, 2006 01:40 PM
A. Because maitakes are well known as healthy food, researchers interested in medicinal mushrooms have studied them extensively. They discovered many maitake compounds with Dramatic health-promoting potential. One of these compounds, maitake D-fraction, has particularly powerful anti-cancer effects.
In lab studies, D-fraction stops the growth of cancer cells and cancerous tumors. Maitake D-fraction stimulates the activity of two white blood cells, macrophages and natural killer cells. These white blood cells then trigger the production of interleukins and other lymphokines, two biochemicals that help mediate the immune response. Maitake also inhibits some of the mechanisms that promote metastasis, or spread, of cancer cells in the lymph system and bloodstream.
Because of this success, maitake D-fraction is now being used in preliminary clinical trials of women with breast cancer. One study has reported significant improvement of symptoms, including reduction of the tumor. The maitake D-fraction was given to breast cancer patients in addition to standard chemotherapy.