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	Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?	Darrell Miller	12/7/23
	The Health Benefits of Berberine	Darrell Miller	9/12/22
	L-theanine is one of the best ways to combat stress and reduce yourheart rate	Darrell Miller	5/2/19
	Fenugreek reduces menopausal symptoms	Darrell Miller	5/2/19
	How to fight the flu effectively with elderberry	Darrell Miller	4/24/19
	Double-blind clinical trial validates cinnamon as natural treatmentfor primary dysmenorrhea	Darrell Miller	2/18/19
	Fascinating study shows vitamin C reduces the risk of cognitiveimpairment	Darrell Miller	1/18/19
	8 key nutrients to include in a plant-based diet	VitaNet, LLC Staff	8/29/18
	Anxiety Relief Without The High? New Studies On CBD, A Cannabis Extract	Darrell Miller	5/23/18
	Dyslipidemia Causes + 5 Tips to Manage It Naturally	Darrell Miller	1/2/18
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Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592)

Date: September 12, 2022 04:22 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Health Benefits of Berberine

Berberine is a natural constituent of herbs such as goldenseal, Oregon grape, and barberry. Clinical studies have demonstrated that berberine helps to support already normal glucose and lipid metabolism.* Because berberine is known for its limited bioavailability, this product includes caprate (C10, a medium-chain triglyceride) to promote optimal absorption and maintenance of gastrointestinal comfort during berberine supplementation.*

Berberine has a long history of use in Traditional Chinese Medicine and Ayurveda for supporting already normal liver function and healthy digestion.* It is also one of the most well-studied botanicals for already normal glucose metabolism support, with research indicating it may work by activating an AMPK-dependent pathway.*

Berberine May Help To Support Normal Glucose Metabolism*

Berberine is a plant alkaloid with a long history of use in Traditional Chinese Medicine for promoting already normal liver function.* extraction process ensures a consistent level of berberine from batch to batch. In addition, this product provides 500 mg of berberine hydrochloride per vegetarian capsule.

Several clinical studies have demonstrated that berberine can help to support normal glucose metabolism in already healthy individuals when taken at dosages of 900 mg to 1,500 mg per day.* In a placebo-controlled human clinical trial involving subjects with prediabetes who were given 500 mg of berberine two times daily for 12 weeks, researchers observed improvements in already normal fasting blood sugar, HbA1c, and triglyceride levels (as well as increases in HDL-cholesterol) compared to placebo group.*

May Also Help To Support Lipid Metabolism*

In addition to its effects on already normal glucose metabolism, berberine has also been shown to help support lipid metabolism in already healthy individuals. In a 12-week, double-blind, placebo-controlled human clinical trial involving subjects with mild elevations in LDL cholesterol who were given 500 mg of berberine two times daily, researchers noted statistically significant decreases in total cholesterol and LDL cholesterol levels (along with increases in HDL cholesterol) compared to placebo group.*

Berberine is a potent botanical extract that has been traditionally used for supporting liver function and healthy digestion. Additionally, it is one of the most well studied botanicals for supporting already normal glucose metabolism. Numerous clinical trials show that it can help maintain already normal levels of fasting blood sugar as well as HbA1c and triglycerides. Furthermore, berberine has also been shown to promote already healthy lipid metabolism by supporting already normal levels of total cholesterol, LDL cholesterol, and HDL cholesterol. Therefore, if you are looking for an herbal supplement to support your overall health and well being, berberine is definitely worth considering.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6443)

Date: May 02, 2019 03:02 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: L-theanine is one of the best ways to combat stress and reduce yourheart rate

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Date: February 18, 2019 08:50 AM
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Date: January 18, 2019 09:17 AM
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Subject: Fascinating study shows vitamin C reduces the risk of cognitiveimpairment

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Date: August 29, 2018 05:53 PM
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Date: May 23, 2018 09:16 AM
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Date: January 02, 2018 08:59 AM
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Date: September 08, 2017 09:14 AM
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Subject: Wheat Germ Oil and Fish Oil Combination Benefits In Hemodialysis Patients

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Date: August 31, 2017 04:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Finding a market for hemp: More than 2000 acres of industrial hemp planted in Minnesota this year

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Date: July 28, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Prebiotic Fiber That Can Help You Lose Weight & Detoxify

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Date: June 10, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why you may need double the vitamin E

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Date: June 09, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Prebiotics reduce body fat in overweight children

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Date: June 09, 2017 11:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Prune drink's double deal: Juice lowers cholesterol and improves gut microbiota

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Date: May 28, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Why Are Diabetics More Prone to Heart Diseases?

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Date: May 27, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Healing Salad - Cure For Vaginal Infections and Candida!

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Date: April 03, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: High-Fiber Diet Keeps Intestinal Walls Intact

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Date: January 10, 2017 12:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Omega-3 supplements can prevent childhood asthma

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Date: January 02, 2017 08:19 AM
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Subject: These Are the Drugs That Cause the Most Overdose Deaths

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Date: December 17, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Replacing carbs with protein? Don't overdo it

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Date: December 12, 2016 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Can You Get Too Much Protein?

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Date: November 29, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Huge study finds a billion people suffer from high blood pressure

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Date: November 17, 2016 06:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Prevent chronic inflammation with a healthy diet

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Date: November 06, 2016 03:09 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Prevent chronic inflammation with a healthy diet

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Date: October 28, 2016 11:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Drinking just two diet drinks a day doubles the risk of diabetes

Did you know that a high sugar intake can increase diabetes? Do you drink diet drinks? They should be healthy for you then, right? Wrong! Did you know that drinking just two diet drinks a day can double the risk for diabetes? Read more in this article to learn the truth between diet drinks and diabetes.

Drinking just two diet drinks a day doubles the risk of diabetes

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3344)

Date: October 27, 2016 01:43 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Drinking just two diet drinks a day doubles the risk of diabetes

While many people drink diet versions of their favorite sodas to stay healthy, studies have proven that these sugar-free drinks may be worse for you. Sugar substitutes may increase the risk of contracting diabetes by as much as four and a half times. Bacterial populations in the body may be altered and appetite increased, a combination that tends to promote more of the possibly damaging habit.

Drinking just two diet drinks a day doubles the risk of diabetes

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Date: August 09, 2016 03:00 PM
Author: Darrell Miller
Subject: NSAID stands for Non-Steroidal anti-inflammatory drugs

NSAID drugs are used by millions of people daily around the world.  Most people do not even think twice about their safety, whether these kind of drugs are safe to use?

These include aspirin, ibuprofen and naproxen. 

They work by inhibiting or blocking COX 1 and 2 Enzyme pathways that cause inflammation in the body.  These drugs do work but have sever health issues, this is why COX 1 and 2 enzyme pathways should never be blocked. 

If you take any of these drugs and other cyclooxygenase blocking drugs, consider the consequences:

• double risk of heart attack and stroke
  
• double risk of death from heart attack and stroke
• Gastrointestinal bleeding, sometimes fatal
• Gastric ulcers
• Kidney failure
• Liver failure
• Blood thinning leading to prolonged bleeding after surgery and injury

There are 16,500 deaths per year from NSAID drugs and the number keeps climbing each year.  Fortunately, curcumin can help lower inflammation safely with out side effects.  Consider taking curcumin instead of reaching for the NSAID drugs.

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Date: March 05, 2014 08:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Celadrin Help Joint Pain?

Celadrin

In clinical studies, Celadrin cream application has been demonstrated to lessen joint torment in less than 30 minutes. This quite viable, all-common mitigating medication holds a protected mix of specific greasy acids and some menthol's to help reduce torment in the joints, advertise joint flexibility and grease and to help smooth sore muscles.

How can it function?

A long time involving usage in addition to strenuous action can certainly reduce the mobility of your joint parts in addition to deterioration your water that ones your joint parts via pain, ultimately producing osteoarthritis. Celadrin gives remedy in addition to rejuvenation of those joint parts. The item functions by lubricating your mobile walls, so improving your extra padding power involving joint parts in addition to bones. Fat have also been proven to avoid your routine involving redness, making an effort to relieve pain within the joint parts in addition to muscular tissues. When you suffer from muscle mass in addition to joint, Celadrin ointment affords the relief you have to make it through your worktime. Analyzed from prime educational facilities in addition to major medical stores, Celadrin ointment gives relief in order to aching muscular tissues in addition to joint parts.

It provides lubrication in addition to works just like a "cushion" among joint parts in addition to cartilage. Rigid joint parts in addition to pain are generally as a result of bad lubrication. Celadrin Product gives remedy in order to fatigued, aching muscular tissues in addition to joint parts. The majority of people think outcomes inside a half-hour.

Scientifically Efficient Joint pain Pain relief

The results involving human being specialized medical trial offers assist the effectiveness of Celadrin ointment. In a double-blind placebo-controlled trial run released within the Journal involving Rheumatology, forty five participants along with uncomfortable knee joint parts - ingested both Celadrin Mutual Proper care Pain relief or even a placebo ointment to put on topically double every day intended for 1 month. Members have been evaluated on several orthopedic procedures involving development. At the conclusion in the examine, your analysts known that the Celadrin had been a simple yet effective therapy intended for enhancing knee mobility, chance to ascend/descend stairways, chance to surge via seated, go in addition to have a seat, in addition to unilateral sense of balance. No changes have been welcomed in your placebo class. Another examine involving 28 people who have arthritis in the knee additionally revealed major improvements throughout knee function, range of motion in addition to pain decrease in a matter of a single week involving utilizing Celadrin ointment.

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Date: February 08, 2014 09:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Can Stevia Do For Me?

 Morning Sugar Crave!

Does that early morning blueberry muffin leave you craving another sweet treat only hours later? Or do you find that you need a candy bar or soda drink in order to make it through the afternoon. If so you are not alone. The unfortunate fact is that many of us have become addicted to sugary treats.

This leads us on a roller coaster ride of sugar highs and lows, where we are constantly trying to give our body the energy demands. Not only does this make it difficult for a us to be productive, it also causes health problems and makes it difficult to maintain our weight.

There is a natural solution that can help you out – Stevia.

Stevia is derived from the leaves of the Stevia plant. It's a natural sweeter which contains no sugar and no calories. People with a sweet tooth also love the fact that stevia is 100 times sweeter than sugar in some cases.

Here are some of the benefits of making the switch from sugar to stevia.

Protect Your Waistline

In 1700 it was estimated that the average person only consumed about 7 pounds of sugar a year. Flash forward to 2014 and the average person is consuming 150 pounds a year. That's 20 times as much sugar! Of that sugar approximately 5% will be used for energy later on, 60% will be metabolized by the body and incredible 35% will be stored as fat so it can be used for energy if required. This is having a huge effect on people's waistline is and is contributing to the massive obesity epidemic which is seen worldwide abysses levels doubled since 1980. Stevia contains no calories but is sweeter than sugar. Even more importantly it does not cause blood sugar levels to rise after it is consumed. Having stable blood sugar levels prevents people from over eating and makes it much easier to maintain a healthy weight.

Prevents high blood pressure

High blood pressure is often referred to as the silent killer. Often people are unaware that they even suffering from high blood pressure until it is too late. In the United States 67 million American adults have high blood pressure. That's approximately a third of the population. The consequences of this are very severe including increased risk of stroke and heart disease. These are the first and third leading causes of death in the United States. According to the medical website WebMD Stevia can be used to reduce high blood pressure and heart burn.

Protecting the teeth

Bacteria feeds on the sugars that you consume and this in turn creates acids. A little acid can help to control the bacterial environment in your mouth. But if there is too much acid over a prolonged period of time it can cause serious problems for your oral health. These acids can destroy the tooth enamel and lead to tooth decay. Stevia does not feed the bacteria in the mouth in the same way as sugar, so it protects your teeth while still providing you with the same delicious sweet taste.

Stevia is a great way for you to enjoy the sweet tastes of the foods that you love without having to worry about your waistline, high blood pressure or destroying your teeth. If you want to satisfy your sweet tooth without damaging your health why not try Stevia?

References:

1.  //en.wikipedia.org/wiki/Stevia
2. //www.webmd.com/diabetes/features/stevia-good-substitute-sugar
   

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Date: February 02, 2014 07:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Check Out The Wonder Grain: Amaranth

The wonder of amaranth

The wonder grain Amaranth has been known to humans for centuries. It was heralded as a staple in the diets of pre Columbian-Aztecs who heralded the plant is granting them special powers. Unfortunately, when the Spanish Conquistadors arrived in the region, they outlawed the crop and went to great lengths to push its existence far from common knowledge. It has only resurfaced on the market in recent decades.

Amaranth plant

A broad and bushy plant, amaranth can grow to around six feet in height. It sports a bright and colorful flower head which contains an immense amount of seeds. It is not uncommon for a single plant to produce seed quantities around the 60,000 mark. The seeds are typically used in the creation of amaranth cereal or flour.

The plant itself is not technically a grain, belonging instead to the same plant family as beets, spinach and quinoa. This classification is the reason it offers nutritional benefits that are closer to those offered by darker, greener plants with more foliage rather than those of true grains. Amaranth plays host to a myriad of different nutrients, including vitamins, minerals, and amino acids. One amino acid in particular, lysine, which is generally present in fairly low levels in other grains, appears in a noticeably higher concentration here. Compared to wheat, Amaranth also carries four times as much calcium and double the content of iron and magnesium. It also boasts an exceptionally high level of protein.

Uses of amaranth

This miracle plant can be prepared with a wide variety of techniques. It can be simmered to produce a consistency not unlike porridge. It can also be mixed with other grains to create a dish that resembles rice. Traditionalists can also toss the grains in a skillet to be cooked like popcorn, producing a crunchy, almost nutty experience. While still not yet immensely popular and therefor sometimes harder to find, amaranth can be an excellent addition to any healthy diet.

Sources:

1. //whfood.org/genpage.php?tname=dailytip&dbid=231
2. //en.wikipedia.org/wiki/Amaranth_gain

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Date: January 30, 2014 05:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Essential Oils Is Flax Seed

Flax Seed as an Essential Oil

A rich source of recuperating mixes, flax seed has been grown for more than 7000 years. Initially grown in Europe, the plant's tan seeds were customarily used to plan salves for aggravated skin and mending slurries for stoppage. Rich in essential oils, or Efas, flax seed oil is utilized to anticipate and treat coronary illness and to assuage a mixture of incendiary issue and hormone-related issues, incorporating fruitlessness.

Flax Seed History

A source of filament for cloth fabric since aged times, the slim flax plant likewise brags a long history as a mending herb. Initially grown in Europe, the plant's tan seeds were customarily used to plan salves for aroused skin and mending slurries for clogging. Today, flax seeds (additionally called linseeds) are best known for the helpful oil that is inferred by pressing them. Rich in essential greasy acids, or Efas, flax seed oil has earned a robust notoriety for treating a reach of afflictions, from coronary illness to lupus.

Benefits of Flax Seed Oil

The essential oils and greasy acids in flaxseed oil are one of its key mending parts. Efas are especially profitable in light of the fact that the form needs them to capacity fittingly, yet can't produce them on its own. Essential greasy acids work all around the form to secure cell layers, keeping them effective at conceding solid substances while excepting harming ones.

One of the Efas in flax seed oil, alpha-linolenic harsh corrosive, is reputed to be an omega-3 greasy harsh corrosive. Like the omega-3s found in fish, it seems to diminish the danger of coronary illness and various different illnesses.

Flax Seed Oil is an Amazing Source of Omega 3:

Just 1 teaspoon holds around the range of 2.5 grams, identical to more than double the sum most individuals get past their eating methodologies. Flax seeds additionally hold omega-6 fattening acids as linoleic harsh corrosive; omega-6s are the same solid fats found in vegetable oils.

Flax seed oil just holds these alpha-linolenic harsh corrosive (Omega 3 oils), and not the strand or lignan segments. Along these lines, flax seed oil gives the Omega 3 profits, for example, lipid-bringing down lands, not the purgative or against growth lands.

Entire flax seeds (not the concentrated oil) are a rich source of lignans (phytoestrogens), substances that seem to emphatically influence hormone-related issues. Lignans might likewise be functional in anticipating certain growths and battling particular microscopic organisms, parasites, and infections, incorporating those that cause mouth blisters and shingles.

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Date: January 03, 2014 05:29 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: VITAMIN - D3:A reservoiur of benefits to sheenful life

Vitamin D3 Sources

A handful of sunshine everyday is what our body requires to retain its sheen and keep our health problems at bay. Human skin when exposed to ultraviolet rays of the sun manufactures vitamin D-3 orcholecalciferol for its consumption. It is recommended that lighter skin individuals receive 10 to 15 minutes of sunlight daily. Darker individuals, on the other hand, should receive almost double the amount of sunlight, up to 25 to 30 minutes daily. Other best natural food source for vitamin- D3 is fish products, such as: cod liver oil, tuna, salmon and sardines.

Apart from the tablets or liquid vitamin D-3 supplements, fortified milk, breads, cereals and eggs are lesser vitamin D3 sources.

Lists of health benefits for Vitamin D-3:

1. VITAMIN D-3 is not only a boon to children's healthy teeth and bones, it is one such nutrient that work as a miracle to treat osteomalacia which causes muscle and bone weakening in adults. It may also reduce major medical risks in elderly if taken in high doses and improves immune system.
2. It promotes calcium absorption thereby preventing loss of bone mass and treating several bone disorders.
3. It lowers the risk of colon, breast, and prostate cancers.
4. Rheumatoid arthritis and psoriasis is improved with vitamin D3.
5. It not only prevents but also help treats rickets which later leads to bone deformities, post menopausal osteoporosis, hypoglycemia and the development of Type 1 diabetes.
6. It also plays a significant role in slowing the degenerative process in multiple sclerosis and Chronic cerebrospinal venous insufficiency.
7. Vitamin D-3 and curcumin synergistically clears brain tangles to help prevent depression and Alzheimer's dementia. There are multitudes of vitamin D receptors in the brain therefore it is believed to maintain and enhance mental health.
8. It prevents PRE-Eclampsia which occurs during pregnancy and produces protein in urine, high blood pressure and edema. It leads to pre-mature labor and is the main cause of death during pregnancy.

References:

1. //voices.yahoo.com
2. //www.naturalnews.com/vitamin_D3.html
3. //www.fitday.com/fitness-articles/nutrition/vitamins-minerals/health-benefits-of-vitamin-d3.html

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Date: December 19, 2013 07:23 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can DMAE Help Memory And Mood?

DMAE

Do you ever feel like you are experiencing lapses in memory or you have a low general mood? There is evidence that DMAE might be able to help with both memory and mood. DMAE occurs naturally in the human brain. When we take supplemental amounts of the compound, brain function effects can be seen.

DMAE as a Supplement

It is thought that the supplement works by increasing the speed of the brain's turnover and synthesis of a neurotransmitter called acetylcholine. This neurotransmitter plays a strong role in maintaining general mental ability. It also works at supporting a stable, healthy memory in older adults. It is also believed that DMAE might work by stopping choline metabolism. This allows the free choline to gather in the blood, go into the brain, and stimulate the cholinergic receptors.

A French double-blind study was performed to measure how much of an impact the supplement DMAE has on both mood and vigilance. Four of the subjects were categorized as having anxiety, and four other subjects were the controls. They were each given 1200mg of DMAE over the course of 5 days. These subjects were measured daily for their EEG and convergence of the inter hemispheres of the brain. In the case of the four subjects that were given the supplement, progressive sync of the two brain hemispheres was found. This is correlated with increased neuromotor control, increased verbal memory, improvement in behavioral tasks, as well as better control of anxiety.

Another use for DMAE worth mentioning is its affects on learning deficiencies like ADD or hyperkinesia. Many doctors prescribe amphetamines for conditions like this, but DMAE has also proven useful. According to studies, hyperactivity and irritability decrease, and scholastic ability improves from supplementing with DMAE.

In addition to improving these conditions there is evidence that DMAE can improve life span, IQ, and motor mechanisms. It is very important to take the correct dosage of DMAE. I would start with taking 200-400mg first, and work your way up from there.

Sources:

1. //en.wikipedia.org/wiki/Dimethylethanolamine
2. //www.life-enhancement.com/magazine/article/105-presence-of-mind-dmae-the-mood-elevating-smart-nutrient

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Date: November 21, 2013 08:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Energy With CoQ10 And L-Carnitine

CoQ10 and L-Carnatine

CoQ10 and L-Carnitine offer double protection for the heart and the brain in just a single tablet. You obtain all benefits for your heart at 100% from CoQ10, while L-Carnitine supports your memory, learning ability, and focus. The exclusive combination of CoenzymeQ10 and L-Carnitine encloses an absorbable, water soluble capsule of CoQ10 and L-Carnitine, which is important for proper usage.

• Cognitive function and concentration support
• Cell membrane health support
• Improves clarity and happiness

• Supporting your heart's energy needs
• Providing essential nutrition for all cells of the body
• Delivering powerful antioxidants, which protect your body

1. //www.webmd.com/heart-disease/heart-failure/tc/coenzyme-q10-topic-overview
2. //www.webmd.com/vitamins-supplements/ingredientmono-1026-L-CARNITINE.aspx?activeIngredientId=1026&activeIngredientName=L-CARNITINE
3. //www.poliquingroup.com/ArticlesMultimedia/Articles/Article/767/Top_12_Reasons_to_Use_Carnitine.aspx
4. //nutritionalengineering.org/coq10-acetyl-l-carnitine-supplement.htm
5. //www.livestrong.com/article/489829-why-should-i-take-l-carnitine-with-coq10/

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Date: October 22, 2013 10:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Facts about Astaxanthin

 Astaxanthin is said to be a carotenoid which belongs to larger class of phytochemicals which is known as terpenes. It is built up of five carbon precursors. It is a metabolite of canthaxanthin and zeazanthin which contains both ketone and hydroxyl fuctional groups. Astaxanthin is a lipid-soluble pigment and is colorful. The color of it is due to the extended chain of conjugated double bonds which is also responsible for the astaxanthin’s antioxidant function. It is found in feathers of some birds, yeast, trout, shrimp, crustaceans, crayfish, krill, salmon and micro algae. The red color of cooked shellfish and red color of salmon is due to the presence of astaxanthin.

How Astaxanthin Helps the Eyes?

When astaxanthin is combined with omega-3 fatty acids and Vitamin E then it helps the eyes to recover the watery condition and it lubricates it too. It helps the eyes to absorb Vitamin E by which it then nurtures and feeds the choroid and optical nerve which is behind the retina. This is the place where the blood vessel enters in to and leaves and this is the place where communication between retina and brain are established. The macula is protected by astaxanthin by its antioxidant activity and it also helps in eliminating the free radicals. It helps in reducing the risk of cataracts and AMD. It also helps in preventing the eyestrain and it also decreases its effects. The inflammation in the muscles of the eyes is decreased by it and it also improves the blood flow of the eyes.

Health Benefits of Astaxanthin

It is considered as a strongest natural antioxidant which crosses the brain-blood barrier and protects the nervous system and brain, works in every part of skin, organs and body, crosses the retinal-blood barrier and thus protect the eyes and it reaches inside and out of every part of the cell. It also helps in repairing the injured tissue.

References: 

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Date: June 04, 2013 01:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Benefits Of Turmeric Extract?

Turmeric extract, also known as Curcuma longa has been used for over 4000 years to treat a variety of conditions. Reputable studies show that it may help control infections, reduce inflammation, and treat digestive problems and some cancers. Historically, it has been widely used in cooking Indian dishes and is much loved due to its curry flavor and yellow color.

Further, it's used to color butter and cheese and has been intensively applied in both Chinese and Ayurvedic medicine to treat wounds and skin diseases.

According to research done at the University of Maryland Medical Center, turmeric extract contains powerful ingredients that stimulate the production of bile and thus can be used to control indigestion.

Let us take a more straight forward look at its main benefits to human health.

Benefits of Turmeric Extract

* Fighting inflammation

Turmeric contains a special substance called curcumin which aside from destroying free radicals lowers the levels of some enzymes in the body that fuel inflammation. Clinical studies have suggested that turmeric's duo benefits (antioxidant and anti-inflammatory) are an essential part of recovering from joint stiffness - useful in relieving rheumatoid arthritis.

* Indigestion

As we mentioned earlier, turmeric can boost the production of bile. One double-blind study (done by The German Commission E) concluded that turmeric may help in improving the functioning of the digestive system by reducing bloating.

* Turmeric and ulcerative colitis

Although turmeric does not seem to help control stomach ulcers, researchers at the University of Maryland Medical Center confirm that can play a central role in people with ulcerative colitis by helping them stay in remission. Recent studies done on people with this disease (who consumed turmeric) showed a lower relapse rate than who took other treatment substances.

* Turmeric extract and cancer

Though most results are still early, there has been a great deal of findings that have painted turmeric in good light as far as treatment of various cancers is concerned. At the moment, scientists are keenly studying its effects on colon, skin, breast and prostate cancers. All the same, turmeric is known for its preventive effects which have something to do with its strong antioxidant properties.

* Turmeric=Good Heart Health

Some substances found in turmeric extract may help reduce incidences of atherosclerosis - a condition closely associated with the occurrence of stroke and/or heart attack. It, in a great way lowers cholesterol levels in blood vessels. Aside from that, it stops platelets from clumping together thus preventing blood clots from accumulating along blood vessels.

* Containing Viral and Bacterial Infections

Turmeric may to some extent kill viruses and bacteria. Some of its active ingredients are as well known to expel intestinal worms.

* Uveitis

Turmeric has been for a long time been associated with good eye health. Well, researchers have recently made breakthrough findings that curcumin (turmeric's main active ingredient) may help treat chronic anterior uveitis. Its efficiency is believed to be at par with corticosteroids.

There are many other health benefits associated with turmeric extract. However, the few mentioned herein are the most important ones that you need to take note of.

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Date: December 28, 2012 11:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Causes High Blood Pressure And What Can Reduce And Prevent It?

High blood pressure is one of the most common conditions people suffer from in first-world countries; throughout the last few decades civilized countries have becomes exponentially more reliant on technology, without forgetting the rise of the fast food industry. In conjunction with the sedentary lifestyles most people lead nowadays, this has led to an increase of people with cardiovascular health problems. According to the American Heart Association, around 33% of adults in the United States are suffering from hypertension.

The silent killer

The disease is not known as the silent killer for nothing, as a person can live with it for years and years without even experiencing any symptoms. However, as time goes by the disease starts to take its toll on the body, with symptoms including dizziness, headaches and nosebleeds. However, if gone unchecked for a long time the condition is going to worsen considerably, eventually leading to the development of serious cardiovascular problems, including coronary heart disease.

What precisely causes high blood pressure?

For starters, one's body fat percentage plays an important role; the more fat a person has, the more the walls of their arteries are clogged, the higher the blood pressure rises. A lack of physical activity has also been known to help the condition develop as it forces your heart to contract itself more often. Intake of products such as tobacco, alcohol, sodium and potassium can all lead to an increase in your blood pressure, as well as your risk of heart disease.

Stress is a factor which often gets overlooked, but the truth is that when you tense up, your heart starts pumping blood faster, which consequently increases the pressure in your arteries. Finally, there is the one factor which cannot be controlled: genetics. Indeed, if a person has a family history of hypertension, that person is likely to suffer from it as well.

While it is possible to treat high blood pressure with chemical over-the-counter pharmaceutical remedies, they often bring about a slew of side effects which can cause problems even worse than the ones experienced with the blood pressure.

Natural Remedies

Fortunately, there are a few natural remedies which can be used to fight the condition.

For starters, you can take magnesium supplements which are sold by numerous companies, generally in the form of capsules. Magnesium is the most common mineral needed by the body and it helps to regulate one's blood levels. If you don't feel like taking supplements, you could always eat foods rich in magnesium, which basically translates to consuming lots of green vegetables, nuts, seeds and unrefined grains. 

Hibiscus tea

Hibiscus tea is another apparent miracle of nature; drinking it on a regular basis will slowly decrease one's hypertension. A clinical study was actually conducted in order to determine the tea's effectiveness, and it was found that it can noticeably improve the condition of those suffering from mild or moderate hypertension.

Coenzyme Q10

Finally, you might want to look into the Coenzyme Q10, a natural supplement which has undergone clinical studies. More precisely, there was a twelve-week double-blind placebo-controlled study involving eighty-three subjects with hypertension. They were treated for the entire duration with 17.8 mm Hg of the Coenzyme Q10, and in the end their pressure was significantly reduced.

Needless to say, there are countless more natural remedies which can help deal with high blood pressure, with the best part being that most of them don't cost much and are readily available for purchase anywhere. In some cases, you can even do it at home by yourself. All in all, as long as there are natural methods to try it is highly recommended that you stay away from pharmaceutical treatments; not only will they burn a hole in your wallet, they may very well leave you worse for wear.

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Date: December 20, 2012 08:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hair Growth Vitamins?

Keep your hair from falling out

Hair and beauty is a trendy industry, which doesn't have any fall back and recession. For a little better hair treatment, you might have to double or triple your budget. So, people living upon a non-stretchable financial background often look for remedies those can be taken in home. Hair fall can be due to shortage of few vitamins too. Few of the vitamins those have active effect upon hair fall are discussed below.

Role of several vitamins in hair growth:

B vitamins help in maintaining the surface of the hair strands and can be taken by eating beans and eggs. Biotin promotes hair growth whereas Vitamin A aids to the immune system so that hair strands stay healthy and less prone to brittleness. Vitamin C helps enhances blood circulation to the hair follicles and scalp making the hair roots stronger. It is found in fruits in adequate amount. Vitamin E helps in oxygen uptake to the scalp, nourishing the follicles.

About Hair Force by KAL:

Hair Force by KAL has the exact proportion of ingredients required for healthy hair. In addition to the above mentioned vitamins it has many useful macro and micro elements like zinc, copper, manganese, silica, inositol, L-methionine, choline, MSM, iron etc.

These are the basic structural components of the biological composition of hair. Vitamin B ingredients like riboflavin, niacin and folic acid control the brittleness of the hair strands. How does Hair Force by KAL work? The minerals and elements provide support to the molecular structure as they are the core building parts of those bio-molecules.

Vitamins keep all desired enzymes and blood circulation to the scalp steady. Few of them also help in tightening the hair follicles. Hair fall is mostly caused by hair brittleness. If all the medicines are taken with time and regular care of the scalp is taken, its guaranteed that significant change in hair fall will appear soon.

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Date: December 20, 2012 02:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium and magnesium - vital to health

Calcium and magnesium are two essential minerals for the body, bringing serious damage if there is a deficiency. Calcium is essential for maintaining bone strength in the body, but also for the functioning of nerve and muscle cells.

Bones perform several roles in the body, but most of us are interested in the preservation of acid-base balance (pH). When the pH of the blood is too acidic , bone alkaline elements released (alkali salts) to neutralize acids. This leads to loss of bone mass (and calcium), while rapidly releasing toxins and heavy metals stored in bone if there are metals and toxins present.

Most of us know that calcium is found in dairy products. True, but the information is not complete. You should know that of all dairy products, yogurt offers the most calcium, about 200 mg in a cup. But if you want the most bioavailable calcium, ie one that is most easily absorbed and can be used fully by the body, then you need to take calcium citrate.

If the food based calcium intake is not optimal and extremely diverse, then you need calcium-based vitamin supplement products. Calcium supplements may be consumed with meals for maximum digestion and absorption. But even if you take dietary supplements, diet should not remain poor, continue to get adequate amounts of calcium from food sources.

Magnesium has an important role in the efficient functioning of the nervous system, muscular system and  enzyme processes in the body. It is necessary for calcium absorption. The ratio of the two minerals is especially important. An adult daily needs for bone health by around 1,500 mg of calcium and 1000 mg of magnesium. Bones are living tissues that rebuild constantly. A healthy diet, exercise, enough sleep (at least 8 hours) and keeping well hydrated with water helps strengthen bones. Calcium and magnesium, combined doubles benefits to our body, especially if they are of citrate in origin. 

Cal-Mag Citrate Why?

Studies have shown that calcium and magnesium citrate is the easiest form to digest with minimal stomach acids. This make it work great for older individuals who have low stomach acids or who are on proton pump inhibitors. 

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Date: December 19, 2012 12:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Curamin Combats Inflammation Pain

Fact: You can manage pain with natural remedies!

Study has revealed the sad fact that four out of every five Americans perceive that pain is a natural inevitable part associated with old age. Athletes on the other hand believe that severe pain is essential for physical fitness. Many people again, think that there are certain disorders that ignite pain and you can do less or nothing to relieve the ache.

In fact, 28% of America's population believes that there is no solution that can eliminate their personal pain concerns. In the contrary, Curamin by EuroPharma is a highly effective herbal remedy that combines four powerful and clinically proven ingredients, into a single award-winning product that offers an ultimate level of pain relief.

Here is a look into how Curamin relieves inflammation pain.

#Curamin's Ingredients The secret behind Curamin's power is blending the best of the best. These ingredients are well known for their fast action in relieving pain associated with inflammation especially in the bones and joints. Here are the four main ingredients used in the formulation of this unprecedented pain reliever.

*DLPA (DL-phenylalanine) This is a double part amino acid (D phenylalanine & L phenylalanine) that impedes the breakdown of the enkephalin compound, also known as the positive mood enhancer. In addition to that, DLPA converts the L phenylalanine into tyrosine so as to enhance the secretion of two brain chemicals; norepinephrine and dopamine, which ease pain and dissolve inflammation.

*Boswellia Boswellia serrata, also known as Indian frankincense is an anti-inflammatory herb used in the Curamin formula. The boswellic acids prevent the hyperactivity of an enzyme called lipoxygenase, which is often associated with inflammation. This way, it effectively combats inflammation pain.

*Nattokinase This natural ingredient is extracted for a Japanese fermented cheese known as natto, hence its name. The production of this beneficial enzyme can be attributed to a certain bacterium called Bacillus natto. Its benefits in relieving pain come through its action of breaking down clots, promoting the circulation of blood. Thickened blood can intensify pain, and by promoting blood circulation, all other Curamin ingredients are well distributed to every single part of the body.

*Curcumin This powerful, natural compound derived from turmeric requires no detailed introduction. It promotes the body's natural ability to combat inflammation and also contains anti-oxidant properties that are very useful in preventing tissue damage. Its functionality in pain relieving is behind its effectiveness in cutting off pathways that lead to inflammation. Numerous studies have also depicted its ability to promote cognitive-enhancing as well as anti-depressant benefits by igniting neuro-protective brain functions and moderating pain neuro-transmitters.

#How Curamin Relieves Pain

This proprietary formula combats inflammation pain by promoting the body's defense mechanism. In addition to that, it features curcumin BCM-95 which has an enhanced oral bioavailability and is highly soluble, thus availing a full spectrum or curcuminoids that fight pain in a flash. Additionally, the amino acids and Boswellia used in the formulation of Curamin helps the body to absorb the pain alienating ingredients quickly, which earns Curamin its well deserved fast-acting characteristic.

Curcumin BCM-95 has extended blood retention; one among the many attributes that makes Curamin stronger than other plain curcumin products. We cannot forget to mention the fact that Curamin is associated to no known side effects. It combats all types of pain ranging from occasional back pain to chronic pain caused by arthritis. So, next time pain becomes a problem, grab a bottle of Curamin and make your life a whole lot easier.

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Date: March 06, 2012 07:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curamin: benefits and ingredients

visit for Coupons

Curamin: benefits and ingredients

It's a well known fact that most chronic pain in whatever part of the body is usually caused by inflammations. Such pain can only be relieved or eased by reducing multiple inflammations in the body. Most over the counter drugs produce dangerous side effects and as such, are greatly discouraged.

Scientists have recently made a breakthrough by discovering a combination of herbs known as Curamin that effectively treat or ease most instances of chronic pain usually caused by presence inflammations in the body

Curamin is an effective natural pain reliever and anti-inflammatory drug that has captured lots of headlines of late. Curamin essentially works by cutting off multiple or several pathways that cause inflammations in the body hence reduce chronic pain as a result.

Curamin is basically a combination of two powerful herbs turmeric and Boswellia along with essential amino acids that helps the body to quickly absorb the pain relieving ingredients.

Curamin is an effective alternative to over the counter pain killers (OTC) which normally produce serious side effects such as liver damage, kidney damage or even in some instances heart attack. Curamin is 100% safe to use meaning it produces no side effects whatsoever.

Curamin is a fast pain reliever that doesn't have to be taken after every four hours unlike most pharmaceutical drugs. Curamin is a fast pain reliever essentially because, it is usually absorbed into the blood stream quickly, hence brings instant relief to patients as a result.

Curamin can be used to ease or treat all manner of chronic pain that include, joint pain, bone pain, back pain, arthritis etc. The plant based medicine contains fout key ingredients, which help in easing several types of chronic pain.

Here are four main ingredients contained in Curamin Curamin ingredients:

Curcumin

Curcumin a natural element derived from turmeric which contains anti -inflammatory properties. Curcumin is also an excellent antioxidant. Curcumin essentially works by cutting off multiple or several pathways that cause inflammations in the body. As if that's not all, Curcumin has also been discovered to contain properties that enhance brain function and is also an effective anti-depressant

Boswellia

Boswellia is another effective ingredient contained in Curamin. Boswellia work by preventing hyperactivity of an inflammatory enzyme called lipoxygenase.

DLPA or DL-phenylalanine

DLPA is a double part amino acid that works by preventing the breakdown of compound enkephalin which is responsible for positive mood or feelings.

Nattokinase

Nattokinase is another very important enzyme that aids the flow of blood. Nattokinase plays a very important role in Curamin as it helps in ensuring that all Curamin ingredients are distributed or taken to all parts of the body for maximum relief against pain. Nattokinase is a very helpful blood thinning ingredient derived from soya plant.

Last but not least, Natural anti- inflammatory remedies or herbs reduce the body's inflammation without producing any negative side effects. The herbs can either be ingested or applied externally. Zero side effects means that an over dose of Curamin can only cause stomach upset or diarrhea only to a lesser extent. Curamin can be bought inform of capsule, powder or tablet format.

Grab some today and feel the difference curamin can make in your life.

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Date: December 21, 2011 07:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are herbs For Hypoglycemia?

Low Blood Sugar (Hypoglycemia)

As people, as human beings we are built for action not for sitting down and be a couch potato all day long. We were created or our body is created with activity in mind and not luxury and laziness. Our body is able to adjust to almost any environment or any change in the environment for that matter if given enough time however the changes that is happening in the world today may be too fast for our body to cope with.

If you notice all these advancements are supposed to make things easier but it seems like it made thing harder and in turn we try to balance, we are obligated to do more work so we try to keep up by exercising a little bit more and by watching our weight and what we eat a little bit more. But in all this time one thing remains the same, our body needs sugar to burn for us to be able to do all those things, even the simplest of brain functions needs sugar or glucose to have it functioning right. Any imbalance between the body’s requirement and the blood sugar supply will cause health problems and one of them is Hypoglycemia.

Hypoglycemia

This is a condition in which the imbalance of the blood glucose levels in the body is pointing more towards on the lower side. Meaning this a condition caused by unusually low sugar levels in the blood. Commonly this is caused by not eating enough as the body requires or maybe too much insulin is taken as why “insulin shock” is a term commonly used for cases of severe hypoglycaemia. Some of the symptoms that are associated with this condition are paleness and sweatiness of the skin, shakiness, heart palpitations and anxiety as commonly caused by high adrenaline levels in the blood as this is the body’s way of counteracting low blood sugar levels.

Other symptoms include weakness, fatigue, double vision, extreme hunger and headaches and these sets of symptoms are caused by brain function impairment which is caused by low glucose levels in the blood. In fact the brain is the organ that suffers the most when it is not able to get the glucose it needs.

Herbs that can help against Hypoglycemia just to name a few…

Ginseng – this wonder herb which has long been used and has been noted to have been effective in Chinese natural medicine is able to aid in sugar absorption in the body. If taken for longer periods of time the logic behind it is that it will be able to regulate blood sugar levels which will help with symptoms like fatigue.

Holy Basil – will be helpful for people with hypoglycaemia through aiding in the management of stress which has been known to worsen the conditions of hypoglycemic individuals.

Gentian – is a bitter tasting herb that has antiseptic and appetite stimulating properties. Its main function though is to be able to stimulate adrenaline production from the adrenal gland which will help in the regulating blood sugar levels.

Gymnema Sylvestre is an ayruvedic herb that has also been shown to help maintain good blood sugar levels.

Chromium picolinate, although not an herb but a mineral can also help maintain good blood sugar levels.

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Date: June 07, 2011 11:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Pain Improve Blood Sugar And Heart Health with OPC Pine Bark Extract

How Does OPC Pine Bark Boost Your Health?

OPC pine bark has become increasingly popular in the supplement industry due to obvious reasons. It is one of the best antioxidant formulas available today. There has been so much research involved in its development, and the studies that followed have published largely positive results. In the past few years it has received a lot of good press, which has significantly contributed to its commercial success.

OPC stands for oligomeric proanthocyanidin, a class of flavonoids. OPC has been in use as a nutritional supplement since the 1980s. To this day, it remains an important source of polyphenolic antioxidants. Moreover, it has been linked to a diverse variety of health benefits, and laboratory studies concerning its effects on human health are well publicized. Pine bark extracts are one of its best known sources.

Promotes Heart Health

OPC pine bark has long been associated with heart health. For one, it has shown to help lower lipid levels in the blood, including cholesterol, triglycerides, and lipoproteins. It interferes with the productions of bad cholesterol into the blood and protects the blood vessels from lipid peroxidation.

In addition, it facilitates normal flow of blood and combats chronic venous insufficiency. It contributes to the upkeep of blood vessel walls and keeps the veins and arteries in prime working condition. By so doing, it promotes proper circulation to the deepest reaches of the body and back to the heart.

Improves Kidney Function

OPC pine bark is particularly good for the kidney as it appears to improve renal function, especially in the context of metabolic syndrome. Central obesity, insulin resistance, diabetes mellitus, and high blood pressure are all symptoms of metabolic syndrome, which takes its toll on the kidneys.

Kidney problems have been observed in people with elevated levels of albumin in the urine. When filters of the kidney are damaged, proteins from the blood such as albumin leak into the urine. OPC pine bark restores health to the capillaries in the kidneys that filters waste materials from the blood.

Counteracts Pain Chemicals

Sufferers of joint pain are likely to benefit from OPC pine bark. Joint pain is often tied to osteoarthritis, the most common form arthritis. It is often accompanied by stiffness and reduced mobility. OPC pine bark has been used as a therapeutic treatment for osteoarthritis and other causes of joint pain.

There is good evidence that OPC pine bark is effective in counteracting pain chemicals and relieving inflammatory pain. In several randomized, double blind, placebo controlled studies, regular intake of OPC improved joint pain and stiffness, reduced reliance on analgesics, enhanced physical function.

Prevents Oxidative Stress

OPC pine bark is free radical scavenger, first and foremost. It is arguably the most researched plant polyphenol largely owing to its potent antioxidant capacity. As an antioxidant, it prevents radical damage from progressing to oxidative stress and promotes cellular longevity.

OPC Pine bark may also help manage blood sugar. What is stopping you from taking OPC pine back daily?

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Date: May 09, 2011 11:14 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Lycopene Help with Prostate Problems

Lycopene and The Prostate.

Lycopene is an organic compound often associated with tomatoes. It is almost always touted to prevent prostate cancer, though the scientific community has not come to a conclusion yet. Scientists are nevertheless positive that it is good for the prostate, for it displays antiproliferative effects on prostate cells. Laboratory studies are very promising as it appears to inhibitory effect on tumor growth.

Prostate health has long been tied to consumptions of foods rich in lycopene. It is a carotenoid that is bright red in color, and as such can easily be obtained from brightly colored plant products, such as watermelon, papaya, pink guava, and apricots in addition to tomatoes. Like other carotenoids, it displays antioxidant properties. In fact, it is the most efficient scavenger of singlet oxygen of all antioxidants that are classified as carotenoids.

Reverses Oxidative Damage

There have been numerous studies on lycopene in the past few decades, and many of them have noted its antioxidant potential. It has become common knowledge that lycopene is good for the prostate, but not all people know that the prostate gland is its primary storage in the human body. Indeed lycopene interferes with the health of cells and tissues that make up the prostate gland.

One study that tracked down malignant prostate tissues prior to scheduled surgical removal studied the effects of regular intake of lycopene. It was documented and published that lycopene concentrations in the prostate doubled and the oxidative damage to DNA in prostate tissues decreased, suggesting a dose-related efficiency in the prevention of cellular damage brought on by free radicals and other reactive oxygen species.

Induces Apoptotic Death

High consumptions of lycopene appear to directly counteract with cancer cells and tumor growth, not only in the prostate gland, but also in the lungs, breasts, ovaries, stomach, and cervix. It has also been tied to other disorders of the prostate, such as prostatitis and benign prostatic hyperplasia, or BPH. It has been noted to slow down cell proliferation that leads to the enlargement of the prostate.

More imporatantly, lycopene seems capable of inducing the cellular process called apoptosis, or programmed cell death, in prostate tissues, most notably in carcinoma regions. This is also evidenced by a significant decrease in prostate-specific antigen in the blood, the reason why lycopene has gained the attention of researchers for prostate health, spurring a number of studies in recent years.

Maintains Prostate Health

Lycopene levels in the human body are largely dependent on dietary intake. As a general rule, the higher the intake of lycopene is, the healthier the prostate becomes. First, it neutralizes reactive oxygen species such as singlet oxygen and free radicals. It also inhibits the multiplication of prostate cells, effectively preventing benign prostatic hyperplasia, which is believed to afflict up to 80 percent of the male population. For those suffering from prostate enlargement, it slows the progression of the disease.

If you are, 40 years old or more you should consider taking lycopene as a preventative daily!

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Date: April 06, 2011 03:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Olive Leaf Boost My Immune System - answer is Yes

Olive Leaf And Your Health

Olive leaf is highly prized for its antimicrobial properties in booth food and supplement industries. For centuries, the leaf of the olive tree has been utilized as a natural antibiotic. It has become the subject of modern day scientific research in the past few years, and preliminary studies appear to be in favor of its age-old claims. In addition, it is now known to modulate immune responses and display potent antioxidant activities.

Olea europaea may be best known for its long association with Mediterranean cuisines although cultures around the world have also used various parts of the plant as flavor enhancers. Its medicinal value continues to gain prominence as recent studies point to the health benefits of the organic compounds it contains. Olive leaf is identified to be an excellent source of the phytochemicals hydroxytyrosol, oleuropein, and oleocanthal, all of which are known for their antioxidant and anti-inflammatory properties. In fact, fresh olive leaves are widely accepted to have an antioxidant content that is 400 per cent higher than vitamin C, that’s double the antioxidant capacity of green teas.

Fights Bacterial and Viral Infections

Olive leaf is antiseptic in nature. It was an important ingredient in poultices used to treat war wounds in the ancient world. Elenolic acid is an organic compound naturally occurring in olive leaf, which is under scrutiny for its antibacterial and antiviral properties. This compound is described to be both bactericidal and bacteriostatic, which means it is directly involved in killing bacterial strains and at the same time interferes with bacterial cellular metabolism. In addition, the antiviral properties ascribed to olive leaf are attributable to its ability to viral protein synthesis necessary for viral replication. This explains why it is effective in the treatment of many known infections, such as candidiasis, shingles, herpes, and Epstein-Barr virus infectious mononucleosis. It has also been reported to reduce the symptoms of colds and flu and shorten their duration.

Scavenges Reactive Oxygen Species

The natural antioxidants found in olive leaf are believed to be the most powerful antioxidants in the market, and as such often marketed as anti-aging. Antioxidants are indispensable in the prevention of the tissue damage caused by reactive oxygen species, or ROS. Free radicals, the best known ROS, are among the group of by-products of oxygen metabolism in the human body. They are also deployed by cells in response to invasive pathogens. Each cell does have its own antioxidant defense, but an imbalance between endogenous antioxidants and ROS is quite common. Chronic stress and physical fatigue are thought to compromise the antioxidant defense of the body, which is restored by antioxidants found in the diet.

Boosts the Innate Immune System

Furthermore, olive leaf strengthens the innate immune system. Its proponents believe that regular intake contributes to the non-specific responses of the immune system, such as the production of neutrophils during inflammation. This type of white blood cells is often the first to engage with pathogens. By speeding up their releases, olive leaf prepares the body against infections.

If you want an Immune Boost, Give olive leaf a try!

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Date: March 22, 2011 03:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Oligonol Good for and How Does It Boost My Health?

Oligonol is the first ever nutritional supplement to contain low molecule polyphenolic oligomers. These polyphenols are derived from the plant Litchi chinensis, also known as lychee in the vernacular. The name oliginol is a portmanteau for oligomer polyphenol, which is widely touted to display bioavailability far superior to high molecular weight polyphenols present in most antioxidant supplements and the plants that they are extracted from. It boasts the most recent innovation of producing higher biological activity by using the low molecule technology developed by the Faculty of Pharmaceutical Sciences of Nagasaki University in collaboration with Amino Up Chemical Co. Ltd.

Polyphenols have long been known to create health effects that are antioxidant in nature. These organic compounds have been tied to quenching reactive oxygen species, or ROS, a natural by-product of oxygen metabolism. ROS like free radicals are in fact deployed by cells in response to potential threats such as invasive pathogens. Given the high reactivity of free radicals, each cell releases endogenous antioxidants to scavenge ROS. However, the body’s antioxidant defense becomes compromised with continued exposure to stress.

At the cellular level, an imbalance between ROS and antioxidants creates a chain reaction termed oxidative stress, which damages cellular organelles and even DNA. This is when antioxidant supplements come to the rescue. Plant-based polyphenols such as those found in teas is widely believed to neutralize free radicals. Those found in lychee are of special note in that they are particularly helpful against oxidative stress. The proprietary low molecule technology of Amino Up Chemical Co. Ltd. processes these already potent polyphenols into more effective monomers and short-chain oligomers.

Protects Cardiovascular Health

Since oligonol was made available nearly two years ago, there have been a number of studies looking into its medicinal potential. A few of the earliest researches were double-blind, placebo-controlled clinical trials that investigated its effects on the cardiovascular system. It has been observed that oligonol appears to lower platelet reactivity, contributing to dilation of peripheral vessels. By so doing, it effectively promotes blood flow, which results in an increase in body temperature.

Counteracts Physical Fatigue

Recovery to fatigue induced by physical exertion is one of the benefits of oligonol that have been well investigated. In one single blind, placebo controlled study involving 47 participants, intake of oligonol lowered post exercise fatigue. The oligonol group of amateur athletes between 18 and 22 of age took two 100-mg oligonol capsules in two 26-day periods with a 9-day wash-out period and saw a noticeable improvement in fatigue recovery in comparison with the control group.

Reduces Visceral Fat

Oligonol continues to excite researchers from around the world with the publication of the study on its effects on visceral fat. There are cell-signaling protein molecules released by adipose tissues that are considered deleterious to human health, and thus called bad factor. Adiposity has been tied to higher mortality, with people having larger waists especially susceptible to many known diseases. Supplementation of oligonol has seen a sharp decrease in abdominal circumference and overall subcutaneous fat.

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Date: March 02, 2011 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is AHCC Good for the Immune System? How So?

AHCC And Immune Health

Active Hexose Correlated Compound, or AHCC, is one of the most commonly used food supplements in Japan largely owing to its effective immune-boosting properties when successfully absorbed by the human body. The earliest important study concerning its activities in the immune system was published in the early 1990’s at Tokyo University, triggering a sudden rise in popularity among consumers in Japan, where it is sold over the counter.

Activates White Blood Cells

It has been observed in the past few years that AHCC boosts the immune system in many different ways in that it participates not only in the innate immune system but also in the adaptive immune system. Of special note is the significant increase in certain types of white blood cells, including natural killer cells, or NK, and macrophages. NK cells are in the employ of the innate immune system and responsible for the disposal of cells infected by viruses. They are often the first line of defense against common viruses such as herpes, containing the damage that viral infection spreads while waiting for specified mechanisms of the adaptive immune system. This is when macrophages come into play along with a cohort of lymphocytes. Their relatively bigger size allows them to effectively engulf pathogenic cells and the enzymes they contain break these pathogens down.

Removes Antigens and Toxins

AHCC also influences the production of antigen presenting cells, or APC. In a double-blind, placebo controlled study involving healthy individuals there was a significant increase in the quantities of APC, notably dendritic cells, in comparison with the baseline, and proteins released by lymphocytes called interferon. Both APC and interferon facilitate the detection of antigens and toxins created by invasive foreign bodies and alert the rest of the immune system of their presence. Dendritic cells are considered the most important group of all APCs in that they present a wide range of antigen presentation by way of phagocytosis or endocytosis, two different ways of catching antigens. By so doing, they make it easier for white blood cells to eliminate antigens and other toxic substances.

Defends against Cancer Cells

Cancer patients are the group of individuals that have benefited the most from AHCC. Early studies yielded data that are now being used to enhance the quality of life of those diagnosed with cancer. Indeed boosting the immune system has proven to play a part in the battle against cancer, and AHCC stimulates the immune system to manufacture a class of white blood cells that actively defend the body against cancer cells by causing tumor cells to die and on the same principle delay the proliferation of malignant cells.

There have been extensive clinical trials well underway in many countries, including China, South Korea, Thailand, Spain, and the US. These studies aim to that rigorously test its efficacy. In fact, AHCC belongs to the group of nutritional products tied to alternative medicine that has been supported by an abundance of data in connection with its safety and recommended dosages.

If you are battling disease, give AHCC a try.

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Date: January 28, 2011 11:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Constipated? Herbs can Help With Constipation!

Sometimes feeling constipated can get in the way of our activities. It can easily be prevented, but our day-to-day routine may not allow us to do so, inasmuch as diet and inactivity both contribute to the common incidence of constipation. Its chronicity could damage our productivity apart from the fact that bowel movement characteristic of constipation can be a real pain. Herbal laxatives that alleviate the unwanted sensation of recurring constipation have been available since time immemorial.

Over a tenth of the worldwide population has been afflicted with constipation, and one may experience it at least once in a lifetime. In the US alone it is the most common reason for digestion-related visits to the doctor, accounting for up to 3 per cent of the total pediatric complaints. Chronic constipation is more widespread among women and children, and becomes a more frequent health problem as we age. While it is not a disease in itself, it may be a symptom of another gastrointestinal ailment, and thus knowing its underlying causes helps in doing away with it for good.

Many different factors give rise to primary constipation, the type most prevalent among adults. Symptoms ongoing for over 6 months is in general associated with lifestyle factors such as diet high in protein but essentially devoid of fiber. High consumptions of meat products translate to increased workload for your digestive tract, and countless patients have reported elevated levels of protein in their diets while constipated.

Dietary fiber has been identified as a substance that aid digestion in that it readily changes into watery slurry, resulting in the formation of stools that induce easy defecation. In fact, fiber is directly involved in preventing constipation by promoting the health of the gastrointestinal tract. The absence of fiber in the diet for long periods of time leads to the slow passage of foods in the alimentary canal.

If you are constipated at very short intervals such as to feel irregularity of bowel movement in a week, then you should act on it as soon as possible. Holding off defecation does lead to constipation. Your gut signals your brain when to release the fecal matter, and if you don’t respond to what your body tells you, the fecal matter turns into an impacted mass that may obstruct defecation.

The use of herbal laxatives eases defecation. One of the functions of the colon is to absorb water from waste products, but certain herbs like aloe lax, rhubarb, and senna display osmotic properties, that is, they attract water present in the alimentary canal down to the colon. The resulting watery environment softens the hardened stool trapped in the colon and promotes motility inside the bowels.

Also, herbal laxatives contain chemical compounds that stimulate the intestinal walls to move the fecal matter, resulting in the evacuation of fecal matter. That being said, it is imperative that you read what the label says on over-the-counter laxatives and strictly follow the recommended dosages to avoid undesirable effects that these compounds may bring.

If you want to avoid herbs, a double serving of magnesium could do the trick as well. if you get enough fiber in the diet and still experience constipation, you should increase your water intake. Lack or water is also the reason for constipation. Your alternative is a good herbal laxative.

Remember to never stay on herbal laxatives long term, short term use of not more than 2 weeks to prevent dependency.

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Date: July 28, 2010 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Free Radical Damage From Toxins With Vitamins And Herbs

There are many things that destroy the immune system. Each day we are bombarded with them in many forms. The following are some of the most common ones that are encountered.

Agene, also known as Nitrogen Trichloride, is used to bleach flour and give it a white appearance. Unfortunately, it can cause epileptic-like fits along with failure of muscle coordination. Excessive use of alcohol also severely impairs the immune system. It increases susceptibility to infection and weakens the central nervous system. Alcohol promotes chronic lung disease, malignancies of the neck and head, intestinal problems, hypoglycemia, diabetes, liver disease, and a whole variety of other problems. B vitamins, folic acid, niacin, vitamin E, magnesium, zinc, and protein are depleted by alcohol. All of these nutrients play a huge role in immune health. Aspartame breaks down in the digestive tract into a toxic material known as methanol. In order to prevent methanol from metabolizing into formaldehyde, a poison, a person needs to take another poison, ethanol.

Glutamic acid is a substance that is found in monosodium glutamate, a flavor enhancer. It affects the central nervous system and can trigger depression, gloomy fantasies, and rage for as long as two weeks following the ingestion of monosodium glutamate. High-diet fat intake increases the levels of bile acids in the colon. This breaks down into deoxycholic and lithocholic acids, both of which are cancer-causing elements. This can cause cancer of both the colon and the rectum. A diet that is high in animal protein and fat can cause cancer of the pancreas, breast, gallbladder, ovaries, uterus, prostate, and leukemia. Junk food such as sweets, white flour, and white sugar products, put a double amount of stress on the body. When too much junk food is eaten, the appetite for good, wholesome food is dulled.

Caffeine decreases immunity in the body, with fibrocystic breast disease being connected with the consumption of foods that contain caffeine. It is often caused by the chemicals methylxanthine, theophylline, and theobromine, which are found in coffee, black tea, cola drinks, chocolate, and other soft drinks. These elements act on hormones that cause breast tissue to develop fibrocystic lumps. Caffeine takes away the body’s own use of iron and inositol, and is often suspected of causing cancer in the pancreas.

Food dyes and flavorings are the culprits in behavioral problems that occur in children and adults, with some of these problems being learning disabilities and hyperactivity. Sodium nitrate is a preservative that is often found in cured meats like hot dogs, bologna, and ham. It has the potential to produce permanent epileptic changes in brain activity and damage the central nervous system.

High protein diets can deplete calcium in the body, especially when the source of protein is an animal product. There are concentrated doses of hormones and antibiotics that are found in beef which suppress the immune system and promote tumor growth. Poly-unsaturated fats undergo a process that produces rancidity in oils. This process releases dangerous free radicals, which eventually lead to cancer.

Heavy metals like lead and mercury can cause serious damage to the nervous system, with even small amounts being considered toxic. Lastly, the wide use of vaccinations and antibiotics is considered to be one of the main causes of immune system disorders.

Our bodies are under constant attack by our toxic environment. Fortunately, with regular vitamin and herb use, one can help the body restore its immune system to proper function so we can live a happier healthier life.

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Date: July 06, 2010 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins for the Heart

It has been consistently revealed by epidemiological research that individuals with a high dietary intake of antioxidant vitamins have a risk that is lower-than-average of cardiovascular disease. This evidence seems to be especially consistent for vitamin E. Additionally, many clinical studies show that magnesium supplementation is of significant benefit in the treatment of cardiac arrhythmias and in reversing the depletion of potassium that comes along with a magnesium deficit. Many cardiovascular events like angina pectoris, congestive heart failure, and cardiomyopathy are related directly to low magnesium status. Coenzyme Q10 is an essential component in cellular energy production. This nutrient is also prevalent in the heart muscle. When tissue levels of CoQ10 are low, there is an association with several cardiovascular complications. Among these are angina, congestive heart failure, cardiomyopathy, hypertension, and mitral valve prolapse. Research has found that the trio of coenzyme Q10, vitamin E, and magnesium plays a crucial role in the maintenance of cardiac health and the prevention of disease states.

The cardio-protective effect of vitamin E seems to come from its ability to bind to LDL cholesterol, which protects it from free-radical induce oxidative damage along with the consequent buildup of atherogenic plaque. Low levels of vitamin E in the blood are a predictive factor of heart health almost 70% of the time.

Studies on the general population have suggested that there is a link between the intake of calcium and blood pressure. Although results of the studies have not been consistent, there are several studies showing that calcium supplementation can lower blood pressure in those individuals who experience hypertension. Overall, those intakes of calcium that are sub-optimal contribute directly to hypertension. It seems that dietary calcium reduces blood pressure by normalizing intracellular calcium levels.

Supplementation with magnesium is of benefit for the treatment of cardiac arrhythmias and the prevention of potassium depletion. Both magnesium and potassium play an important role in the functioning of the heart. Several studies have found that there is improvement in heart function in those patients that have cardiomyopathies when they supplement with magnesium. Since magnesium acts in so many ways to enhance cardiac function and optimize cellular metabolism, magnesium is widely recognized as a critical nutrient for general cardiac support.

Several double-blind studies have taken place in those patients that experience various cardiomyopathies in order to show the benefits of CoQ10 supplementation. One study reported an 89% improvement rate in 80 cardiomyopathy patients who were treated with CoQ10. The coenzyme also appears to moderate blood pressure through the usual mechanism, as it lowers cholesterol levels and also stabilizes the vascular system with its antioxidant properties. Because of this, it is able to reduce vascular resistance. Several studies on CoQ10 supplementation have confirmed that this nutrient posses the ability lower both systolic and diastolic pressures by up to ten percent.

There are other nutrients that play important roles in optimizing cardiovascular health and reducing hypertension. Among these nutrients are gamma tocopherol, calcium, magnesium, l-carnitine, acetyl-l-carnitine, procyanidolic oligomers, phenolic compounds, and lycopene. As you can see there are many natural supplements that can help the cardiovascular system. Remember to always consult your doctor before adding supplements to your diet while on prescription drugs. Look to your local or internet health food store for quality vitamins, herbs, and specialty formulas to boost your health and wellness.

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Date: May 17, 2010 10:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants and your health

There is an impressive amount of scientific evidence supporting the health benefits of supplementing with a wide variety of antioxidants. Consequently, there are many health practitioners who have begun to recommend high dietary intakes of these crucial nutrients in order to prevent against oxidative stress. It was anticipated over two decades ago by leading researchers that high-dose supplementation with antioxidants is developing a significant role in the prevention and treatment of a lot of today’s common illnesses. It should be noted that antioxidants do not work in isolation. When an antioxidant neutralizes a free radical, it, itself, is oxidized and must be regenerated by another antioxidant before it can be used again. Because of this, it is crucial to supplement with a wide variety of antioxidants, in order to reflect what actually occurs in nature.

Vitamin C, an aqueous-phase antioxidant, is the main guard against oxidative attack in the extra-cellular matrix, as well as within the cytoplasm of the cell. Vitamin C happens to be a substrate for eight different enzyme systems that are involved in various cellular functions. Among these functions are collagen synthesis, ATP synthesis in the mitochondria, and hormone biosynthesis. Its main antioxidant partners are vitamin E and beta carotene, both of which help to regenerate vitamin C.

Of all the antioxidants, it seems as if vitamin E offers the greatest protection against heart disease because of its ability to protect the cardiovascular system from oxidative damage. It is lipid-soluble, making it an important component of the cell membrane, where it works to protect the cell against lipid peroxidation and control oxidation-induced inflammatory events. Recently, the gamma tocopherol form of vitamin E has shown a great deal of promise in its ability to reduce the risk of several oxidative stress related disease.

Beta-carotene is a member of a diverse group of photosynthetic pigments. It plays a huge role in human nutrition. As an antioxidant, it possesses a double-bond structure that allows it to react effectively with single oxygen radicals, absorbing and diffusing their energy. Beta-carotene also acts as a precursor for vitamin A by supplying a portion of the body’s requirement for the vitamin. This act alone plays a central role in the chemistry of vision. Beta-carotene and vitamin A both prevent the oxidation of cholesterol, reduce oxidative damage to DNA, and disable oxygen free radicals that are produced by exposure to sunlight and air pollution. These antioxidants are also involved in the activation of gene expression and the control of cell differentiation.

When combined together, vitamin C, vitamin E, and beta-carotene produce and important antioxidant trio that plays a huge role in fighting oxidative and inflammatory events. There are several other antioxidants that should be noted due to their ability to work synergistically with the vitamin C, vitamin E, and beta-carotene trio. These include vitamin A, alpha-lipoic acid, lycopene, coenzyme Q10, and the antioxidant mineral, selenium. In order to determine whether a nutrient provides antioxidant support, scientists question whether the product contains vitamin C, vitamin E, vitamin A, beta-carotene, alpha-lipoic acid, lycopene, coenzyme Q10, and selenium and to what strength these vitamins and minerals are per serving.

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Date: October 20, 2009 12:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Feverfew Herb

For thousands of years feverfew has been used for the treatment of various ailments. History is full of references to feverfew. Dioscorides, an ancient Greek herbalist, recommended the use of feverfew almost two thousand years ago, as he valued the herb for childbirth, fevers, melancholy, and congestion of the lungs. It was also suggested for arthritis. In 1772, feverfew was suggested to be used to treat painful headaches. Many people believe that feverfew obtained its name from its use as a remedy for bringing down fevers, but this has been determined to be incorrect. Instead, the name came from the traditional Old English name for feverfew, featherfew. Featherfew came from the feather-shaped leaves of the feverfew plant.

Feverfew has been used for a long time as a natural remedy for pain relief, as it is considered an excellent remedy for migraines. This herb was used to treat any kind of pain and helped with chills and fever. Additionally, it helps in relieving colds, dizziness, tinnitus, and inflammation from arthritis. The herb works gradually and with a gentle action that allows the body to heal itself.

The most popular use of feverfew is in the prevention and relief of migraine headaches. In a study, those given the placebo had an increase in frequency and severity of headaches, nausea, and vomiting. On the other hand, those given the feverfew capsules had no increase in frequency or severity of migraines. A randomized, double-blind, placebo-controlled, crossover study was done on seventy-two volunteers. One group received capsule dried feverfew leaves, while the other received a placebo. The group taking feverfew showed less severity of attacks and a reduction in symptoms that were associated with migraines, including vomiting. There was a definite improvement in the group using feverfew and no serious side effects resulted. Because some forms of migraines are believed to be associated with abnormal platelet behavior, feverfew may be beneficial as it has been found to help restrain the release of serotonin from platelets. This prevents a migraine from occurring.

It is thought that feverfew may also be a useful treatment in cases of rheumatoid arthritis. This is because of its ability to inhibit the formation of inflammation-promoting compounds like prostaglandins and leukotriene. This herb seems to have similar properties to non-steroidal anti-inflammatory agents (NSAIDs), like aspirin. Feverfew may actually be even more effective with a lot fewer potential complications. Some of the studies involving feverfew and migraines have shown that feverfew may also lower blood pressure.

The leaves and flowers of the feverfew plant are used to provide alterative, analgesic, anti-inflammatory, antimicrobial, aromatic, bitter, carminative, emmenagogue, febrifuge, nervine, parasiticide, mild purgative, stimulant, and vasodilator properties. The primary nutrients found in this herb are iron, niacin, manganese, phosphorus, potassium, selenium, silicon, sodium, vitamins A and C, and zinc. Primarily, feverfew is extremely helpful in dealing with chills, colds, fever, headaches, sinus headaches, and inflammation.

Additionally, this herb is very beneficial in treating aches, ague, allergies, anxiety, arthritis, insect bites, poor circulation, dizziness, gastric disorders, nervous headaches, hot flashes, indigestion, and menopausal symptoms, absent menstruation, nervousness, tinnitus, and vertigo. For more information on the many beneficial effects provided by feverfew, please contact a representative from your local health food store.

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Date: August 24, 2009 11:32 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Caralluma extract

Caralluma is a succulent plant that is part of the cactus family. It can be found growing wild in Africa, the Canary Islands, India, and southern Europe, Sri Lanka, and Afghanistan. The herb has been used in Indian for centuries in order to curb appetite. It is a portable food for hunting and also an endurance enhancer. This herb was also used during periods of famine in order to curb appetite.

The caralluma plant is part of the Apoxynaceae family. It has been eaten in rural Indian for centuries, raw, as a vegetable with spices, or preserved in chutneys and pickles. It is often found as a roadside shrub or boundary marker. Caralluma has been used as a portable food and thirst quencher for hunting. Caralluma is mainly used for its ability to suppress hunger and appetite, while enhancing stamina. Tribesmen on a daily hunt will often only pack some caralluma to sustain themselves, which is why it is commonly known as a famine food in India.

The working class in India used this plant not only as an appetite suppressant, but also to increase energy and endurance. Caralluma can be coked as a vegetable, pickled, used in chutneys, or eaten raw.

This herb seems to block the activity of many fat-promoting enzymes in the body. It forces fat reserves to be burned. One double-blind, placebo-controlled, randomized clinical trial on caralluma extract, which involved fifty people, showed significant reductions in all key indicators of weight loss.

This plant is also believed to affect the appetite-control mechanism that is found in the brain. When we eat, nerves in our stomach send a signal to the brain’s hypothalamus. This is the appetite-controlling center. When the stomach is full, the hypothalamus informs the brain that it can stop eating. When a person feels hunger, it is the result of the hypothalamus sending a signal to the brain to eat. The interference with these signals, or even creating a sign of its own, is done by caralluma. Through this, the brain is tricked into thinking that the stomach is full, even if the person has not eaten.

Patients who use caralluma have reported having more energy. Additionally, they tend to gain lean muscle mass while they lose fat. This herb not only reduces fat synthesis, but it also boosts the burning of fat. This makes more energy available for the body as a whole.

The plant has no known toxicity or side effects. However, it is wise to consult a health care professional before supplementing with this, or any nutrient while on prescription medications.

The entire caralluma plant is used to provide anorectic and energy boosting properties. The primary nutrients found in this herb are bitters principles, flavones glycosides, megastigmane glycosides, pregnane glycosides, and seponins. Primarily, this herb is extremely beneficial in dealing with low energy and obesity. It also acts as an appetite suppressant. For more information on the many beneficial effects provided by caralluma, please feel free to contact a representative from your local health food store.

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Date: June 24, 2009 12:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium, Magnesium And Vitamin D

In February 2006, the findings of an $18 million double-blind placebo-controlled study were published in the New England Journal of Medicine. This study was conducted by the Women’s Health Initiative (WHI) and was on the protective effect of calcium and vitamin D. The New York Times reported on this study, declaring that the study found that there were no clear benefits to calcium pills. In this article, the fact that the women who stuck to their supplementation regime experienced 29% reduction in hip fractures was dismissed. This result is rarely achieved, even with use of the strongest pharmaceuticals.

This study was designed to determine whether postmenopausal women who were given calcium and vitamin D would have a lower risk of hip fracture. The intervention group was given 1,000 mg each day of calcium carbonate, along with 400 IU of vitamin D. Although these women portrayed a greater preservation of hipbone density, the decrease in risk of fracture of 12% was not significant as a whole. The fact that many of the women who were included in the study were under sixty, and therefore, not typically at risk for fractures, causes these results to be unsurprising.

The results that were found were also skewed as a result of the fact that compliance with the prescribed daily intake was only 59% by the end of the study. 41% of the study participants had fully stopped taking the prescribed daily dosage of calcium and vitamin D, with 24% having discontinued the supplementation altogether. With such an unexpectedly low compliance rate, along with the fact that the projected hip fracture rate was over twice what was actually observed, the power of the study was reduce to only 48%. As a result, the trial had less chance than a simple flip of a coin to find anything but the largest of differences in a risk for fracture.

Despite these shortcomings, the researchers looked at the subgroups, and found different pictures emerging. Looking only at the women who mostly stuck to their prescribed regime, researchers found that a reduction in fractures of 29% was experienced. Additionally, those women over sixty experienced a reduction in the risk of fracture of 21%. These results are actually remarkable, especially after considering the many problems which clouded the accuracy of the data. Unfortunately, reporters did not look at these findings, causing a slanted account of the study to be published. Because of this, the media failed to acknowledge what were actually significant findings.

Additionally, the design of the WHI study disregarded the fact that a reduction of fracture risk is actually dependent on several factors other than calcium. Studies have actually shown that magnesium is also of equal important in the treatment and prevention of osteoporosis, as a deficiency plays a central role in the development of the disease. Postmenopausal women and those women with osteoporosis usually have low bone-magnesium content, exhibiting other indicators of magnesium deficiency that are not seen in non-osteoporotic women. Also, calcium competes for absorption with magnesium, meaning that postmenopausal women who increase calcium intake without also increasing magnesium intake can impair their absorption of magnesium. With this knowledge, the failure of the researchers to include magnesium supplementation along with calcium and vitamin D caused the potential for a study that could cause harm on the patients. With the results as they are how can we trust studies that are conducted when the patients who participate do not follow the rules? For those who want to prevent osteoporosis, calcium, magnesium, and vitamin D when taken together can help slow and prevent the onset of brittle bones.

Calcium, magnesium, and vitamin D come in capsule, tablet, and liquid softgel forms at your local or internet health food store. Always look for a name brand calcium, magnesium, and vitamin D supplement to ensure quality and purity of the product you purchase.

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Date: January 20, 2009 09:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Soap Bars

With the earth-friendly topic being on so many people’s minds lately, consumers are realizing that using natural personal care products is a simple way to start with a greener lifestyle. Consumer demands for natural personal care products has actually experienced double digit growth consistently for the past few years, with this trend not expected to slow. At the same time, non-natural personal care is typically seeing less than a five percent growth.

Natural is currently one of the fastest growing subcategories of personal care, with a large crossover clientele emerging and many mass, grocery, and drug stores are now offering natural products. Success has moved natural ingredients into mainstream brands, opened doors to food, drug, and mass merchant distribution, and driven major consumer brands to enter the market. Larger mass market companies are now realizing the extreme growth potential and profitability of the natural market as compared to the traditional personal care market.

Manufactures have been trying many different things in the soap market including making soaps for sensitive skin, using fair trade ingredients, and discovering new ways to make creamier and more moisturizing soaps. Consumers are looking for their natural personal care products to have the same easy use and performance level of chemical-based personal care products. There is also an increase in interest in using food-based ingredients, as it is appealing on a consumer level due to the familiarity, because if you can eat it, it must be safe.

Fragrance-free and sensitive-sin products are also on the rise, with thirty percent of the population reporting some sensitivity to fragrance, while more than eighty percent report that exposure to fragrances is bothersome, with many synthetic fragrances containing phthalates, which are linked to birth defects and health-related issues. However, the consumer must know that there is actually a difference between unscented and fragrance-free. Unscented products mask the odor of the actual formula with a fragrance, which leaves the potential for skin irritation and allergic reactions.

The Natural Products Association recently launched a Natural Care Product Seal and Standard so that consumers could more easily identify products with truly natural ingredients. Adhering to these requirements can prove difficult for manufactures of natural soaps. Soaps and creams present several challenges to formulators who are seeking to avoid chemicals and synthetic materials. Soaps made according to the above standards will cleanse skin and hair, although they may have an appearance and texture that was different than many consumers are use to. These soaps may be thin, create minimal foam, and may have a shorter shelf life than other natural products that are made according to alternative ingredient standards.

Although bar soaps are staple products year round, liquid soaps are currently gaining popularity, as bar soaps are often drying to the skin and have a high pH. Liquid soaps, on the other hand, have a pH closer to that of skin and also have the ability to moisturize. The market should see an increase in liquid soaps in the future, as the population ages and skin is drier and needs more moisture, leaving the moisturizing abilities of liquid soaps to meet these needs.

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Date: December 11, 2008 12:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Inositol And Choline

Inositol is a member of the vitamin B complex family, being referred to as vitamin B8, but is not strictly a vitamin because it is biosynthesized in your body. Vitamins are essential substances that are not manufactured by your natural biochemistry, and must be taken in your diet. However, to all intents and purposes it works like a member of the vitamin B family.

The main function of myo-inositol (the commonest isomer of inositol) is in the health of cell membranes, particularly those that comprise the marrow, eyes, intestines and the brain. Without proper regulation of the cell membrane, the cell cannot function effectively. Some of its effects include healthy hair and controlling estrogen levels. It is also believed to help to reduce cholesterol levels in the blood.

A deficiency will result in hair loss, eczema, increased blood cholesterol levels and eye abnormalities. You might also suffer constipation, although this is not as serious a condition as those preceding. It is present at highest levels in the heart and brain, which indicates where it is mostly used, although it also helps the liver to break down fats and enables the nerves and muscles to operate as they should.

Those that are depressed are frequently found to have low inositol levels in their spinal fluid, so it is believed to play a part in that condition. It is known that the substance takes part in the function of the neurotransmitter serotonin, which is known to play a part in depression, and initial signs are that its use in the treatment of depression could be effective. Neurotransmitters are responsible for passing messages across the gap (synapses) between nerve cells, their messages being decoded by the neuroreceptors. A healthy nervous system depends on healthy neurotransmitters.

For these reasons, inositol has also been tried on other conditions of the nervous system. These include bipolar disorder, bulimia, panic disorder, obsessive compulsive disorder and attention deficit disorder. So far, results have been inconclusive as to its effectiveness, but it is early days yet and field tests are continuing.

A test carried out in Beersheva, Israel, in 1997, found that treatment with inositol produced significant improvement in the depression of 28 patients after four weeks on the Hamilton Depression Scale1, and 21 patients tested with panic disorder (with and without agoraphobia) showed significant improvements in their condition, including agoraphobia. Results on 13 patients with obsessive compulsive disorder also showed significant improvement. These were all double-blind tests.

However, not all tests have been so conclusive, and a study on 42 people with sever depression who did not respond to conventional antidepressant, also failed to respond when inositol was added to their medication.2 Results are therefore not conclusive.

Four hundred people took part in a double-blind test that indicated a possible improvement in the symptoms of polycystic ovary syndrome when treated with inositol 3,4 and another that inositol treatment on patients taking lithium could help reduce the symptoms of psoriasis, a skin condition believed to be caused by a reaction of the immune system and nerves.5

The supplement has also been found to be just as effective as Luvox (fluvoxamine – similar to Prozac) after four weeks treatment. Although these results are good, they are inconclusive, and more data is need before any indisputable conclusions can be drawn. However, treatment with inositol might be worth considering if conventional treatment for these conditions has been unsuccessful.

The most common natural form of inositol is myo-inositol, an isomer of cyclohehexanehexol, a carbocyclic polyol that form the structural basis for secondary messengers in the cells of eukaryotes.

A secondary messenger system is one whereby a signaling molecule is released in response to a signal from a primary messenger such as a neuroreceptor, which then activates certain intracellular proteins known as effector proteins that exert a response from the cell. An example is cAMP (cyclic adenosine monophosphate) that is a secondary messenger that activates protein kinases and allows them to phosphorylated proteins.

Eukaryotes are organisms that contain cells composed of complex components contained within a cellular membrane, and that also contain a nucleus. Examples are fungi, plants and all animals. Examples of non eukaryotes include the bacteria family.

It is frequently recommended that inositol is most effective when taken with an equal amount of choline, although this might be due to the fact that when inositol deficiency is detected, choline is also frequently deficient. Both are vitamin B family like, and both are lipotropic, in that they aid the breakdown of fats in the body. It is not clear whether this is true or not, but taking both would certainly not harm you, and might be of great benefit.

Inositol is not essential, because it can be obtained from beans, nuts, seeds, whole grains, cantaloupe, brewer’s yeast, liver and vegetables. Bacteria in the gut also act on the phytic acid (inositol hexaphosphate) contained in citrus fruits to form inositol.

However, be careful if you drink a lot of coffee. It destroys inositol, and if you are taking the supplement medicinally, steer clear of coffee during your period of treatment because it will lose its effect. Excessive coffee drinking can also result in a general depletion of inositol from your diet, and hence a deficiency. In such a case you are advised to take a supplement, preferably along with choline that might also be deficient.

Although there have been no adverse side effects reported, no specific longer term safety studies have been carried out on inositol. Because of the way it works, inositol should be avoided by people with liver or kidney disease, and also by expectant or nursing women. It should be avoided by young children until safety tests have been carried out, and it is believed that it can cause manic effects in those suffering bipolar disorder.

Other than for these specific cases, trials with many times the average daily intake of the substance, it currently appears safe to take inositol as a long-term supplement. However, as with all such supplements intended for specific disorders, you should seek the advice of your physician.

References: 1. Levine J: Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev,Beersheva, Israel ur Neuropsychopharmacol, 1997 May, 7:2, 147-55

2. Nemets B, Mishory A, Levine J, et al. Inositol addition does not improve depression in SSRI treatment failures. J Neural Transm. 1999;106:795-798.

3. Gerli S, Mignosa M, Di Renzo GC. Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2003;7:151-9.

4. Gerli S, Papaleo E, Ferrari A, et al. Randomized, double-blind, placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS. Eur Rev Med Pharmacol Sci. 2007;11:347-354.

5. Allan SJ, Kavanagh GM, Herd RM, et al. The effect of inositol supplements on the psoriasis of patients taking lithium: arandomized, placebo-controlled trial. Br J Dermatol. 2004;150:966-969.

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Date: November 10, 2008 10:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Guggul

Guggul is a natural herb supplement that may help lower cholesterol, yet few in the Western hemisphere know much about it. Guggul is otherwise known as the Mukul myrrh tree, and is a plant of the Burseracae family with small red or pink flowers.

It is found across central Asia over to North Africa, although is very common in the northern areas of India where the climate is more semi-arid than equatorial. Guggul does not like a lot of water and can thrive in ground where the soil has few nutrients. Its Latin name is Commiphora wightii, and it grows about 12 feet high.

It has been predominantly used in the Ayurvedic medicine of ancient India, and like many such ancient remedies and treatments, is now used in modern medicine to treat specific conditions: conditions such as some forms of heart condition, where it has been found to be able to lower your blood cholesterol levels, weight loss and some forms of arthritis and other inflammatory conditions.

However, it has been used so successfully over the years, particularly in India, which it is now in danger of extinction and is contained in the Red Data List of the World Conservation Union that lists endangered species. So what is so special about this plant that makes it so popular? To get the answer to that we have to go back a bit in its history, although not quite as far as the two or three thousand years that it is known to have been used in traditional Hindu medicine.

The active ingredient is found in the sap of the tree, and is used to fight against obesity and other diseases that can be caused by excess weight or cholesterol, such as arthritis, obesity and atherosclerosis. Until recently it has had very little support for its claims from conventional medicine. It was in the 1960s that an ancient Sanskrit text was found that recommended guggul as a treatment for high cholesterol levels. Since that discovery, research has focused on the plant's anti-cholesterol properties, and a great deal of evidence has been gathered supporting the claims of that ancient text.

So much so that the Indian government has approved the use of guggul for the treatment of high cholesterol levels, largely because it has been found very effective in reducing the levels of 'bad' LDL cholesterol in the blood while increasing the levels of the beneficial HDL cholesterol. Several trials have supported this, including one study involving 228 patients that showed the extract to be equally as effective as the anti-cholesterol drug clofibrate.

That is not all, and other studies included one in which a decrease in LDL cholesterol of almost 13% was measured in a double blind study involving 61 subjects, of which around half received a placebo. An average 12.7% reduction in LDL cholesterol, 12% in triglycerides and 11.7% in total cholesterol was experienced by the group given the guggul extract. Every 1% drop in total cholesterol is associated with a 2% decrease in the risk of heart disease.

Guggul reduces the levels of harmful cholesterol in your blood by converting it into bile. The plant extract contains substances given the name guggulsterones that block the activity of a protein that regulates the metabolism of cholesterol in your body known as FXR (the Farsenoid X Receptor). This protein can increase the risk of you contracting heart disease by preventing the liver from converting cholesterol into bile acids, so that the concentration of cholesterol in your blood continues to build up.

The problem with bile acids is that once they reach a certain concentration in your body, the FXR comes into play and stops more being produced. Guggulsterones prevent the FXR from doing this, and so helps the liver to destroy more cholesterol. There is a reason for the body not allowing too much bile acid to be generated, but for those with excess cholesterol, it is more beneficial for this regulation to be prevented, and more cholesterol to be destroyed by the liver.

It is the resin of the plant that is prized, being extracted from the bark in much the same way as rubber is tapped. It is also used in fragrances and perfumes in addition to its medicinal uses, and the dosage generally recommended is 1500 mg (1.5 grams) twice daily. However, it is not recommended for those suffering liver disease, irritable bowel syndrome, Crohn's disease or any form of diarrhea, and should not be taken by those on beta blockers.

It is not only for its cholesterol-lowering properties that guggul is prized, however. Another property it possesses is its ability to render blood platelets less sticky, and so reduce the risk of coronary disease, and prevent the formation of blood clots and thrombosis.

Another use it has found is in the field of weight loss, where it has been found effective in reducing the weight of obese adults. It does so by the activation of lipolytic enzymes and increased levels of triiodothyronine (T3), believed to be due to the formation of T3 from T4 (thyroxine) in the liver.

T3 increases the metabolic rate, and the rate of the breakdown of glycogen and gluconeogenesis: the biosynthesis of glucose. It also causes cholesterol to be broken down and increases the rate of lipolysis - the breakdown of fats stored in fat cells in the body. Studies have shown that those taking guggul lost up to 6 times the weight of a control group within 15 days, and the practice is going along with the theory.

Not only that, but when you are on a diet, your body is likely to respond by decreasing levels of triiodothyronine, and so reducing the rate at which fat burns. Hence, your diet does not help you top reduce weight as quickly as it could. Guggul, however, stimulates the production of T3, and so you are not only taking less fat into your body, but are also burning it up at an accelerated rate.

Other uses to which the resin has been put are based upon its anti-inflammatory properties. It has been found to be an effective treatment for some forms of arthritis and also in the treatment of acne. The active inflammatory ingredient is believed to be myrrhanol A, a polypodane-type triterpene, which would also explain the antioxidant effect of guggulipid on lipid peroxidation.

Guggul is a versatile plant, and a good supplement to take for anybody suffering increased lipid or cholesterol levels, and who wants to increase the weigh-loss effect of their diet. However, make sure that you purchase a supplement standardized on its guggulipid content.



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Date: October 21, 2008 12:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Grape Fruit Pectin Fiber

Grapefruit pectin fiber is a source of soluble fiber that can bind to cholesterol and inhibit the formation of atherosclerosis. It is also effective in maintaining good blood sugar levels, and promoting a healthy colon. However, before discussing how grapefruit pectin fiber works in these ways, it is first necessary to explain how they occur in the first place.

CHOLESTEROL LEVELS

First cholesterol. This is a steroid lipid, most of which is biosynthesized by your body rather than being present in your diet. Although it has a bad name health wise, cholesterol is actually essential to good health because it helps your digestive system break down fast, it strengthens cell walls and is a major ingredient in the manufacture of vitamin D by your liver. It is also essential for the formation of several hormones, including cortisone, cortisol and aldosterone by the adrenal glands, and also of estrogen and testosterone. A bloodstream without cholesterol is therefore not good for you.

Given that cholesterol is essential for good health, then why does it have such a bad press? The root cause of that is that cholesterol is not water soluble, and to be carried round the bloodstream to where it is needed it needs some transport. For that, it uses low density lipoproteins (LDLs). However, it’s not a return journey, and to get back they must use another form of lipid known as a high density lipoprotein (HDL). The protein part is water soluble, wile the lipid part can attach to the cholesterol and carry it around the bloodstream.

The problem arises with free radicals, which are oxygenated molecules that are generated by the body’s metabolism, and also created from pollutants, such as pesticides and cigarette smoke, and the UV portion of daylight. These can oxidize the low density lipoproteins so that they can be attacked by phagocytes (while blood cells) deposited as plaques in the artery walls. This hardens and thickens the arteries, reducing the heart’s blood supply which in turn can cause strokes and heart attacks.

This can be prevented in a number ways, the major of which are by consuming plenty antioxidants in your food, mostly contained in phytochemicals (plant chemicals), reducing your LDL cholesterol levels to the minimum needed by your body, and also by increasing the HDL levels in your bloodstream by as much as possible.

Grapefruit pectin fiber can bind to cholesterol, and prevent it from being deposited in the artery walls by the oxidized LDL. A sixteen week double blind study (neither the subjects nor those carrying out the test and analyzing the results knew who were given the placebo) found that grapefruit pectin successful reduced the low density cholesterol level of 27 subjects by 10.8% and overall plasma cholesterol by 7.6%. These volunteers were at a medium to high risk of atherosclerosis due to a high LDL cholesterol concentration in their blood.

Animal studies have also been carried out, whereby animals were fed a high cholesterol diet, and those fed a high fat diet were found to have an average of 45% narrowing of their arteries, and those fed the same diet, but with added grapefruit pectin fiber, were found to have only 25% narrowing, thus corresponding with the results of the human volunteers.

BLOOD SUGAR

It is essential that you maintain a stable level of sugar in your blood since the body reacts to low blood glucose by making you feel hungry, and thereby forcing you eat. If you are trying to lose weight you will find it very difficult if your blood sugar levels fluctuate. Grapefruit pectin can reduce the rate at which carbohydrates enter your bloodstream, and therefore the rate at which sugars are absorbed.

Studies have also indicated that pectin can even out your blood sugar concentration, so that you experience fewer fluctuations or sudden spikes that can make you feel either very hungry, and so binge on carbohydrates, or very satisfied so that you eat nothing at all. The maintenance of a stable level of glucose in the blood is necessary for a normal life since it is that that determine your need to eat food. If your blood sugar is low, the desire to eat high calorie carbohydrate food is uncontrollable.

This is the theory behind the so-called ‘grapefruit diet’. You eat a grapefruit prior to a meal, and allow it to be digested. The grapefruit pectin will make you feel full and so eat less, so that you can eat normal foods, but still lose weight. Many people take the grapefruit pectin in supplement form for its ease and economy of use. It is also more convenient since you don’t have to carry grapefruit around with you everywhere you go.

A Healthy Colon

Like any other soluble fiber, grapefruit pectin fiber is a dietary fiber that can help to maintain the health of your colon. In fact it is the only one of the basic four fibers of lignin, cellulose, hemicelluloses and pectin that is soluble. Although referred to as soluble, pectin softens and expands and provides substance and added weight to faeces in order to allow it to pass easier through your colon.

Other than ensuring the easy passage of your stool through your colon, and avoiding constipation, grapefruit pectin fiber can help to prevent excessive growth of bad bacteria in the intestine, and because it accelerates the passage of substances through the colon, there is less time for toxic or cancerous substances to be in contact with your bowel lining. It is that which causes bowel cancer, and grapefruit pectin fiber can help to prevent it.

Fiber can also help to prevent diverticulosis, where the intestinal wall develops small sacs and becomes weakened. It also prevents hemorrhoids, eases the symptoms of IBS (irritable bowel syndrome). In short, it offers many benefits for the health of your colon, and can help to cure many bowel conditions.

However, it is important that you don't just rush into using any form of dietary fiber, but take it gradually. You start with a small intake, and then increase it slowly; since it is not absorbed through the intestine too much can lie in your colon and ferment, causing any number of intestinal problems. When used properly it can ease the symptoms of irritable bowel syndrome, but if used to excess, or too quickly, can actually cause the same symptoms, in addition to blocking the absorption of essential minerals such as iron, zinc and calcium.

Grapefruit pectin fiber can do a great deal for health, including maintaining good blood sugar and cholesterol levels, and helping to keep your colon healthy. It is available in convenient supplement form, but make sure that you drink sufficient liquid each day in order to prevent the fiber blocking your intestine rather than allowing free passage of waste product into, through, and out of your colon.

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Date: October 14, 2008 10:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The pediatrics academy has raised its earlier recommendation to 400 IU per day.

The American Academy of Pediatrics (AAP) today announced that it has doubled the amount of vitamin D recommended for infants, children and adolescents. The increase, from 200 international units (IU) to 400 IU per day, starting in the first few days of life, was detailed at the group’s annual meeting in Boston. The new advice replaces an academy recommendation issued in 2003.

"We are doubling the recommended amount of vitamin D children need each day because evidence has shown this could have life-long health benefits," said Frank Greer, M.D., FAAP, chair of the AAP Committee on Nutrition and co-author of the report. “Supplementation is important because most children will not get enough vitamin D through diet alone.”

"Breastfeeding is the best source of nutrition for infants. However, because of vitamin D deficiencies in the maternal diet, which affect the vitamin D in a mother’s milk, it is important that breastfed infants receive supplements of vitamin D,” said Carol Wagner, M.D., FAAP, member of the AAP Section on Breastfeeding Executive Committee and co-author of the report.

The new advice is based on mounting research about potential benefits from vitamin D besides keeping bones strong, including suggestions that it might reduce risks for cancer, diabetes and heart disease. But the evidence isn't conclusive and there is no consensus on how much of the vitamin would be needed for disease prevention.

"We know 400 IU a day is safe and prevents rickets," Greer said. "We don't have any idea if that amount of vitamin D is enough for other diseases. We also don't know if anything over 400 is safe."

The AAP also made these recommendations:

Infants who are breast-fed or partially breast-fed receive 400 IU a day of vitamin D in supplements, beginning in the first few days of life, continuing unless the infant starts taking at least one quart a day of vitamin D-fortified formula or whole milk, although whole milk should not be introduced until the child has turned 1. Non-breast-fed children and older children should also receive a vitamin D supplement of 400 IU per day.

Adolescents who do not obtain 400 IU of vitamin D per day through foods should receive a supplement containing that amount.

Children at increased risk of vitamin D deficiency (for example, those taking anti-seizure medications) may need higher doses, but this should only be done in consultation with a health-care professional. The new recommendations were expected to be published in the November issue of the journal Pediatrics.

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Date: September 26, 2008 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lutein 20mg (FloraGlo)

Maintains Healthy Visual Function*

It has been well established that lutein is present in high concentrations in the retinal tissue of the human eye. However, a study was conducted in human volunteers to determine whether taking lutein in supplement form actually increased the density of the carotenoid pigments present in the macula. In this study of eight individuals, researchers estimated the density of the macular pigments prior to having each individual take 10 mg of lutein daily in supplement form for 12 weeks. Plasma lutein concentrations were measured at 4-week intervals. During the first four weeks of the study, plasma levels increased five-fold from pre-supplement measures, and then remained at this level for the duration of the study. It was also shown that, due to increased deposition of lutein in optical tissues, macular pigment density increased by an average of 5.3% at the 4-week mark, and continued to increase until the duration of the study.1

A study was also conducted to investigate the possible role of specific nutrients in protecting the lens of the eye against aging, a risk factor for compromised visual function. The study was comprised of 376 individuals aged from 18 to 75. Of the nutrients measured, it was found that the lenses of individuals with higher concentrations of lutein and zeaxanthin showed less of an effect from the aging process. The investigators concluded that these carotenoids might play a protective role in supporting the maintenance of healthy vision.2

The Age-Related Eye Disease Study (AREDS) was a landmark study of the effects of diet and antioxidant supplementation on eye health. The study enrolled over 3500 subjects aged 55 to 80 years who were followed for approximately 6 years. Among the data collected in this multi-faceted study was a self-administered Food Frequency Questionnaire (FFQ). The AREDS Report No. 22 examined the data from the FFQs and determined that, of the nutrients evaluated, only lutein and zeaxanthin were directly related to maintaining eye health with statistical significance3. These findings corroborated similar results of an earlier multi-center study published in the Journal of the American Medical Association that also found that those with a higher intake of lutein and zeaxanthin maintained healthier eye function.4 These promising results have spurred the design of a second major clinical trial (AREDS2), which is currently enrolling participants to study the impact of supplemental xanthophylls (FloraGLO® Lutein and zeaxanthin) and other nutrients on age-related eye health.5

In addition, a double-blind placebo controlled trial was performed in ninety individuals who had signs of compromised visual function. Individuals were divided into three groups and received either 10 mg FloraGLO® lutein, 10 mg FloraGLO® lutein plus a multivitamin/multimineral formulation, or placebo for 12 months. In both the FloraGLO® lutein and FloraGLO® lutein plus other nutrients groups, improvements were seen in mean eye macular pigment optical density, visual acuity and contrast sensitivity. No improvements were noted in the placebo group.6 These results demonstrate FloraGLO® lutein’s beneficial effect on maintaining healthy visual function.

Newly published research has demonstrated that lutein and zeaxanthin supplementation may enhance visual performance under glare conditions. Forty healthy subjects took daily doses of 10 mg FloraGLO® Lutein plus 2 mg zeaxanthin for six months. They were evaluated for changes in macular pigment, glare disability and photostress recovery at the onset of the study, and at 1, 2, 4 and six months. After six months, subjects experienced an average increase in macular pigment optical density (MPOD) of 39% compared to baseline, and all but two participants experienced some increase in MPOD. This increase in MPOD was also directly related to measured improvements in visual performance after exposure to bright light, as well as photostress recovery.7 This study suggests another way in which lutein and zeaxanthin can help support optimal visual function in healthy individuals.

Potent Antioxidant Protection*

Most of the beneficial effects of lutein are ascribed to its potent free radical scavenging abilities. It is well-known that lutein is a carotenoid related to beta-carotene and possesses antioxidant activity against a number of reactive oxygen species.8

More direct evidence for the free radical scavenging activity of lutein is found in studies of its effects on human lens epithelial cells. Cell cultures were exposed to ultraviolet light after pretreatment with lutein or alpha-tocopherol. Both nutrients were found to reduce ultraviolet-induced damage to lens epithelial cells. However, lutein was shown to have significantly higher photoprotective activity than alpha-tocopherol9 demonstrating its potential as a high-powered antioxidant.

A further review of the mechanisms of lutein in conferring a protective role reveals evidence for its antioxidant activity in various body tissues. Lutein has been shown to be an effective antioxidant in vitro as well as in experimental models of a number of body systems.10

Supports Healthy Skin*

A recent randomized, double blind, placebo-controlled study has demonstrated the positive effects of oral and topical administration of lutein on skin health parameters (surface lipids, hydration, photoprotective activity, skin elasticity and skin lipid peroxidation). Forty female subjects were divided into four treatment groups. Treatment options included oral administration of 5 mg of FloraGLO® Lutein twice daily or placebo and topical administration of 50 ppm FloraGLO® Lutein twice daily or placebo. Each treatment group received either an active oral treatment with a placebo topical treatment, a placebo oral treatment with an active topical treatment, both active treatments, or both placebo treatments. Statistically significant improvements were seen in all five parameters tested in all treatment groups compared to the group receiving only placebos. The greatest overall improvements were seen in the group receiving both active oral and topical treatments, while lesser but still significant improvement was seen in both the active oral only and the active topical only groups. Additionally, oral administration of lutein conferred superior photoprotective activity (as measured by skin surface redness after exposure to ultraviolet light) and prevention of lipid peroxidation (as indicated by levels of malondialdehyde in skin lipids after exposure to ultraviolet light) than either topical lutein or placebo.11

Diverse Cinical Benefits*

Evidence from various experimental trials suggests that lutein may play a protective role on the circulatory and cardiovascular systems. Its antioxidant activity may also extend to the heart, skin, lungs and blood vessels, making it a nutrient with diverse clinical benefits. Lutein possesses the ability to promote the health of many body tissues.12

Suggested Adult Use: One softgel daily with food, or as directed by a health care professional.

Does Not Contain: milk, egg, wheat, sugar, sweeteners, starch, salt, or preservatives.

Scientific References

1. Berendschot TT, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Opthalmol Vis Sci. 2000 Oct; 41(11): 3322-6.

2. Berendschot TT, et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Arch Opthalmol. 2002 Dec; 120(12): 1732-7.

3. Age-Related Eye Disease Study Research Group. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol. 2007 Sep; 125(9): 1225-32.

4. Seddon JM, et al. Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration. JAMA. 1994 Nov; 272(18):1413-1420.

5. www.nei.nih.gov/neitrials/viewStudyWeb.aspx?id=120. Clinical Studies Database. Age-Related Eye Disease Study 2 (AREDS2). Last Updated 2/28/2008. Viewed 5/15/2008.

6. Richer S, et al. double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr; 75(4): 216-230.

7. Stringham JM and Hammond BR. Macular pigment and visual performance under glare conditions. Optom Vis Sci. 2008 Feb; 85(2):82-8.

8. “Lutein and Zeaxanthin”. PDR Health. www.gettingwell.com/drug_info/nmdrugprofiles/nutsupdrugs/lut_0164.shtml

9. Chitchumroonchokchai C, et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. J Nutr. 2004 Dec; 134(12): 3225-32.

10. Krinsky NI. Possible biologic mechanisms for a protective role of xanthophylls. J Nutr. 2002; 132: 540S-542S.

11. Palombo P, et al. Beneficial Long-Term Effects of Combined Oral/Topical Antioxidant Treatment with the Carotenoids Lutein and Zeaxanthin on Human Skin: A double-Blind, Placebo-Controlled Study. Skin Pharmacol Physiol. 2007; 20: 199-210.

12. Mares-Perlman JA, et al. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. 2002; 132: 518S-524S.

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Date: August 28, 2008 09:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Garcinia Cambogia

Garcinia Cambogia is found naturally in India and parts of Asia, and also on the Pacific coast of South and Central America all the way from Peru up to Mexico, and likes a humid forested environment. Also known as Brindall berries, garcinia is believed to act as an appetite suppressant and allows you to lose weight by diminishing your desire for food.

The Malabar tamarind, as it is also known, is about the size of an orange resembling a small pumpkin, and an extract from the fruit and rind is used in several weight loss products. The health risks presented by synthetic diet pills render a natural product extremely attractive were it to be effective. So can Garcia curb your appetite? What is the scientific evidence for it, and what biochemical route would it take?

Although tests on animals have been very positive, human results have been inconsistent. In some double blind tests using a placebo, weight loss was up to three times that of the control, but in others there was no apparent difference between those taking garcinia, and those given a placebo. However, doubts have been raised of the validity of some of the negative tests, so what does science tell us?

The active ingredient in the cambogia extract is hydroxycitric acid (HCA), which is a powerful inhibitor of ATP citrate lyase, an enzyme that catalyzes the reaction between citrate and Coenzyme A to Acetyl CoA and oxaloacetate. Since the acetyl CoA is necessary in the synthesis of fatty acids and lipogenesis (the conversion of glucose to fatty acids), then anything that inhibits the biosynthesis of acetyl CoA must help to reduce the amount of fat stored in your body.

By inhibiting this reaction, that occurs outside the mitochondria so is not a direct part of the Citric Acid Cycle, HCA should theoretically suppress the formation of fats from carbohydrates, reduce food intake and thereby induce weight loss. But that is not the only mechanism.

A study at Georgetown University in Washington found that after 8 weeks of taking the garcinia extract, there was a 5.4% reduction in body weight and body mass index, and a significant reduction in low density lipoproteins (LDL) and triglycerides with an associated rise in high density lipoproteins (HDL). This is good news for those suffering from high cholesterol levels, since the LDL lipoproteins are those that carry cholesterol to the major blood vessels, and which when oxidized by free radicals deposit fatty plaques on the artery walls. These plaques constrict the arteries and the resultant atherosclerosis can lead to cardiac problems and strokes. HDL lipoproteins carry cholesterol back to the liver for destruction, and is known popularly as ‘good cholesterol’.

The studies also indicated modifications to certain indicators of the status of fat deposits in the body and of appetite modifiers in the brain. In this respect they found 38% decreases in serum leptin and increases in serotonin levels of 44%, and the excretion of fat metabolites in the urine increased from between 32% and 104%.

These are significant findings, and further research has indicated that HCA helps to suppress appetite. Serum leptin is an indicator of the level of fat stores in the body, and as the leptin levels in the blood reduces, the hypothalamus is given an instruction to increase the appetite so as to increase the fat levels again. However, it is believed that HCA possesses leptin-like properties, and this signal is either not generated or is modulated.

The increase in serotonin has the same effect. It is known that serotonin controls the appetite, although the exact mechanism has not yet been established. What is known is that serotonin activates certain neurons and melanocortin-4 receptors (MC4R) in the brain, that not only curb appetite but also block the effect of other neurons that would normally increase appetite by blocking the effect of MC4Rs.

This is how the banned anti-obesity and serotonin inciting drug Fen-Phen operated, and it appears that the hydroxycitric acid in garcinia cambogia extract acts in a similar, but safer, way. The problem with drugs such as Feb-Phen was that they created cardiac problems which could be dangerous to obese people whose hearts might have been weakened.

However, now that the biological pathway by which serotonin controls weight is believed to be known, if not fully understood, the way is becoming clearer as to how safer weight loss pills, acting through appetite suppression, might be developed. It also provides a valid scientific explanation for the effect of garcinia cambogia extract which might in itself prove to be that safer way.

The biochemistry supports the evidence of its effect on those wanting to lose weight, and also bolsters the claims that those tests and trials found to be negative were in some way flawed. Until the full chemical pathway is understood, the factors that can lead to flawed tests are unknown, although one could be the use of excessive fiber in some trials that could reduce the effect of the extract.

One of the effects of HCA is to limit the ability of your body to convert carbohydrates into fat (the Acetyl CoA inhibition mentioned above). That, combined with suppression of your appetite and a higher rate of thermogenesis, prevents the body from storing excess carbohydrates as fat. Instead you will have increased energy levels, so you should exercise to use this up while taking garcinia extract. For this reason it is popular with athletes and bodybuilders seeking an energy source that has not yet been banned from sport.

Although diet pills based on the same principle had side-effects and could make the user feel on edge, there are none known with garcinia. However, it is possible to reduce the absorption of some essential nutrients due to appetite suppression, so do not exceed the recommended dose. An excessive amount can also led to gastric discomfort, but none of these effects have been noted when the recommended doses have been adhered to.

However, if you are diabetic, pregnant or a nursing mother, you should consult with your physician or health professional before taking the extract. Garcinia Cambogia presents no specific risk to such people, and this warning should be given for all non-prescriptive treatments that your physician might be unaware of you taking.

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Date: August 07, 2008 06:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Probiotic

Probiotics are dietary supplements containing potentially beneficial bacteria for the small and large intestines. Probiotics, which means "for life", have been used for centuries as natural components in health-promoting foods. This beneficial bacterium is important in recolonizing the intestinal tract with good bacteria during and after antibiotic use as well as supporting overall health and wellness.

Probiotics are not the same thing as prebiotics which are non-digestible food ingredients that selectively stimulate the growth and/or activity of beneficial microorganisms already in the human colon. Probiotics are live microorganisms (in most cases, bacteria) that are similar to beneficial microorganisms found in the human gut. The use of good probiotics is important in healing many chronic gastrointestinal problems that are so often associated in those with autism spectrum disorder (ASD) and IBS.

One study performed in a 4-week, double-blind, placebo-controlled trial of 60 individuals with IBS, probiotics treatment with lactobacilli showed markedly beneficial to slowing down the bowels and reversing IBS. Two Scientific studies over the last 50 years show that probiotic organisms can improve the nutritional quality of foods, produce antibiotics, anti-carcinogens, and substances that break down and recycle toxins for their human host.

Historically, people used fermented foods like yogurt and sauerkraut both as food preservatives to limit spoilage, and to support their intestinal and overall health. Fermented foods such as sauerkraut also contain probiotics. Today probiotic bacteria such as Lactobacillus and Bifidobacterium are added by food manufacturers to fermented foodstuffs to improve their nutritional value.

There are, however, other foods that may contain added probiotics, such as sour cream, fruit juices and buttermilk. Food ingredient suppliers are now making it easier to add probiotics and prebiotics to foods and beverages by offering blends of synbiotics with the right proportion of pro- and prebiotics to obtain the desired beneficial health effects, as well as improved survival of the live bacterium strains.

Beneficial bacteria thrive and work with your digestive tract and immune system, along with Essential Fatty Acids, to protect you against illness and disease. It is also important to have a healthy balance of beneficial microbes to avoid sickness and disease and to keep your body stay nutritionally sound. Probiotic beneficial bacteria are involved in every aspect of your health. Along with beneficial bacteria, we show how supplements such as Essential Fatty Acids and Green foods provide the foundation for good health and provide a nutritional base for probiotics to grow and flourish in the body.

The most common form for probiotics are dairy products and fortified foods. Probiotics are products aimed at delivering living bacterial cells to the gut ecosystem of humans and other animals, whereas prebiotics are non-digestible carbohydrates delivered in food to the large bowel to provide fermentable substrates for the friendly bacteria to grow and thrive.

Probiotics are available to consumers mainly in the form of dietary supplements and foods. Because candida infection is very common due to overuse of antibiotics, several studies suggest that probiotics may be effective at preventing candida overgrowth as well as reversing it; candida is a good target pathogen for future probiotic research.

Although they are thought to be essential for health, because they can sustain themselves in the body under normal circumstances, there is no recommended daily intake of probiotics. By consuming foods with probiotics, you can increase the number of healthy bacteria, boost your immunity, and promote a healthy digestive system.

If you can not eat the foods that contain friendly bacteria, there are always probiotic supplements available from your local health food store. As always, it is best to check with your doctor or health care provider before starting any new supplements with medications. Probiotic formulas are a safe and effective means to deliver friendly bacteria to where it is needed, the colon.

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Date: July 22, 2008 01:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: DHA

DHA is a fatty acid that is essential for many body processes and structures. Fatty acids are the building blocks that create lipids, which are important nutrients that make up 25 to 45 percent of total body energy for most of those who are living in industrialized countries. The majority of dietary fatty acids are made from dairy products, meat, margarine, and vegetable oils.

Lipids are important because they store and transport energy from one part of the body to another and they also insulate and mechanically protect certain parts of the body. Any fat that is eaten is converted by the body into fatty acids, where it is then burned for energy, stored, or synthesized into other acids which are called prostaglandins. Some fatty acids are also vital structural components of cell membranes. DHA is part of a special class of highly concentrated, long-chained, polyunsaturated fatty acids called omega-3 fatty acids. Omega-3 fatty acids are looked at as one of the most fundamental molecules in the structure and activity of the membranes of all cells. They have a huge influence on the production of cellular regulatory compounds which are known as eicosanoids. They also are highly specialized in their function in neurological tissues, especially the retina of the eye. It is also very likely that omega-3s have specific and beneficial effects on the heart muscle, while they also influence the production of substances that control immune responses.

Fatty acids are short-chained, medium-chained, or long chained. Short-chain fatty acids are water-soluble and absorbed directly from the intestine into the bloodstream. They are generally used for immediate energy and can be found most abundantly in dairy products. Long-chained fatty acids are more emphasized when it comes to health concerns as they are stored in cell membranes and have a huge affect on membrane protein function. Their behavior in tissue membrane is what makes them greatly influential in health.

Besides the length of the chain, fatty acids are also described by their saturation. Saturation means how many hydrogen atoms the fatty acid carries. Fatty acids that carry as many hydrogen atoms as they can are called saturated fatty acids, while those that lose a pair of hydrogen atoms become unsaturated. This loss of hydrogen atoms creates a double bond between the two carbon atoms on either side of the missing hydrogen atoms. Those fatty acids that have one double bond are called monounsaturated fatty acids, while those with two or more double bonds are called polyunsaturated fatty acids. Most omega-3 fatty acids are highly unsaturated and have five or more double bonds.

EPA and alpha-linolenic acid are most commonly found in plant sources. DHA and EPA are made in phytoplankton, which is consumed by fish, mollusks, and crustaceans. The above reason is why these two essential fatty acids are found mainly in the aquatic food chain. LNA and EPA cannot substitute for DHA in all metabolic functions, even though DHA and EPA are more able to cover for each other in certain metabolic functions. It has been found that LNA is less effective than EPA which is less effective than DHA in enriching tissues, meaning that food sources such as vegetables and seed oils are not as good of sources than sea foods or other foods that are enriched with DHA and EPA. DHA in itself provides most of the health benefits displayed in research, to take essential oils that contain no DHA would limit the health benefits discussed above and from other sources. Have you had your DHA today?

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Date: July 14, 2008 03:28 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can the Fatty Acid CLA Help me Lose Weight ?

CLA is conjugated linoleic acid, a compound known as a trans fatty acid due to its stereochemistry, and while trans fatty acids are generally regarded as harmful, CLA is not because it is conjugated. This means that it has alternate single and double bonds in the backbone carbon chain, and the overall energy of the molecule is therefore reduced.

Linoleic acid itself is one of the omega-6 fatty acids, the 6 referring to the double bond at the sixth carbon from the omega and of the carbon backbone chain. It is believed to be the cause of heart disease and obesity due to its increasing use in the diet at the expense of omega-3 fatty acids. When the molecule is conjugated, however, the fatty acid has different chemical properties to the standard isomer, and natural CLA is mainly found in cattle products, such as beef and dairy products.

Conjugated linoleic acid is present in cattle because it is formed when linoleic acid is converted to oleic acid by rumen bacteria, that are responsible for the microbial fermentation of the feed of ruminant animals such as sheep and cattle. When oleic acid is formed, so too is CLA. However, the form used in supplements is manufactured from vegetable oils, and therefore suitable for use by vegetarians. The usual vegetable oils used are safflower oil and sunflower oil.

It is believed to possess several beneficial properties, including antioxidant and anti-cancer properties, but it is for its ability to reduce body fat that it is best known to most people. A growing amount of information is being collected on the use of CLA as a supplement in the weight loss industry, although there are as yet no definitive mechanisms that explain its action. However, recent studies have indicated it possess properties that can help to reduce the levels of low density lipoproteins in the blood, and reduce the possibility of atherosclerosis due to LDL oxidation by free radicals.

It is also theorized that CLA in some way regulates the prostaglandin biosynthesis that controls the level of hormones in the body that can regulate growth. An increase in growth hormones is one way in which athletes promote an increase in muscle bulk, while reducing their fatty tissue mass. CLA is also purported to increase thermogenesis, and so promote the loss of body fat and overall weight.

Although most studies on the effect of conjugated linoleic acid in reducing body weight have been carried out on animals, recent animal studies have indicated that might not so much reduce weight, as to increase muscle bulk while reducing that of body fat. The end result, therefore, is not a loss of weight, but a leaner body that has more muscle and less fat. All it needs is the results on animals to be transferred to humans, and this, of course, is frequently the case. However, initial studies on the use of CLA in the human diet have been very positive, so the signs are good.

Most scientific progress in human biochemistry has been obtained by virtue of prior studies on animals. These studies, of course, have been beneficial to the animals, making them leaner and much fitter than they otherwise would have been. It is believed that the same will be true of humans taking CLA as a supplement. In fact, recent studies are split about 50/50 with regard to the effects on humans.

While some studies have shown no benefit, about an equal number have shown a positive benefit in the reduction in the mass of fat in the body. Some of the negative studies may have been flawed in measuring total body weight, and not the relative amounts of muscle and fat, and also basing their results on people already with a low level of fat in their body. In that respect, then, the results look very favorable, and taking CLA as a supplement is likely to help you to reduce fat and increase muscle, if not altogether lose total body weight. However, is that not the end result that most people want? They might not want to be lighter in weight, just to have more muscle mass and less fat tissue.

In a study shown at a 2002 Experimental Biology meeting, it was shown that is was possible to substantially reduce body fat mass by taking CLA alone, and when it was taken in association with guarana, both the size and the number of fats cells in the body were reduced by 50%. However it has also been shown that CLA can be oxidized by free radicals shortly after ingestion, and that sesame lignans help to prevent this. Since sesame lignans can also be used in conjunction with CLA to reduce fat by increasing the level of fatty acid oxidation in the liver, than the benefit of CLA seems obvious.

The antioxidant effect of CLA is one possible explanation for its anti-cancer properties, though there are others. Its antioxidant properties also have an anti-catabolic effect, in that it can help to prevent the wastage of muscle tissue. The FDA has published studies that attest to these anti-cancer properties. Diabetics, however, should consult with their physician before taking CLA as a supplement, since there is a body of thought that it reduces sensitivity to insulin. Others believe the opposite, so more studies might be needed in this aspect of the substance before it can be said to be safe for use by diabetics.

Over recent years, the American diet has increased significantly in its content of the undesirable linoleic acid, due to its ubiquitous presence in margarines, and has reduced in CLA due to modern farming methods. Cattle feeding techniques have resulting in a reduction of CLA in meat products and milk, although eggs are still a rich source, and the CLA in eggs can resist temperatures used in normal cooking methods such as frying, boiling, etc.

It is this CLA deficiency in the diet that has been proposed as one of the reasons for the current obesity problem in the USA. The European diet contains more beneficial fatty acids in general than the American diet.

However, there is an increasing body of evidence being accumulated that collectively that suggests almost unequivocally that CLA can help you lose body fat. Unless you are diabetic, there are few if any contra-indications and an increasing number of people are finding it effective not only to lose body fat, but to replace it with hard lean muscle.

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Date: April 29, 2008 10:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ButterBur Extract

Butterbur extract is taken mainly from the rhizome, root and leaves of the butterbur, a member of the daisy family. They are very hardy and have creeping underground rhizomes and large leaves like those of rhubarb. Another name given to it is the sweet Coltsfoot, and they generally grow in the temperate climates of Europe, North Africa and South west Asia. They like damp conditions, specifically marshes and ditches, and also riverbanks where there are always plentiful supplies of moisture.

It has been used by Native Americans for headaches and inflammation, and has been shown to be an effective remedy for hay fever and to provide relief from painful menstrual cramps. Butterbur has also been used throughout the middle Ages to treat fever and the plague, and has been recorded in the seventeenth century as being used for asthma, wounds and coughs. However, one of its most important applications is in restore bladder function in the incontinent and semi-incontinent.

Urinary incontinence is typified by an unusually high frequency of urination – more than 8 times a day, an immediate strong urge to pass water or leaking and involuntary urination. Any two of these three indicates urinary incontinence. As people age their bladders become smaller, and by definition the periods between urination will reduce. This does not, however, suggest that bladder size is the cause of urinary incontinence.

Urination is caused by the contraction of the smooth layered muscle that surrounds the bladder, called the detrusor, a contraction in turn caused by neurons both in the brain and in the detrusor itself. This naturally contracts and expands according to the volume of urine in the bladder, and once the bladder is about half full the brain will tell you that the detrusor is ready to contract to expel the urine. However, if the time is not convenient, the cortex will suppress this desire until a more convenient time.

In incontinence, the desire is suppressed but the neurons still fire to contract the detrusor, expelling urine at inconvenient moments. Butterbur contains the sesquiterpenes petasin and isopetasin, which are known to reduce spasms in smooth muscle tissue and in vascular walls. It can therefore be used to control the involuntary spasms that cause urine leakage or expulsion against the patient’s wishes. These sesquiterpenes are at highest concentration in the roots of the plant.

The effect that the sesquiterpenes have in inhibiting the synthesis of leukotriene in leukocytes tends to support this effect, since leukotrienes can cause contraction of vascular and smooth muscle tissue. Not only this, but the spasmolytic effect could also be explained by the inhibition of cellular calcium caused by the petasin isomers.

Many studies have indicated that the effectiveness of butterbur extract is also useful in the prevention of migraines. There has been a lot of research carried out on the use of butterbur extract on migraine sufferers, and the effective dose appears to about 75 mg twice daily. There is little evidence of it being a cure but as a prophylactic there appears no doubt of its efficacy: there have been too many positive results against placebos for its effect to be deniable.

It is significant that leukotriene can cause constriction of the small blood vessels in the veins, and so affect the flow of blood. Butterbur, in inhibiting its biochemical production, helps to keep these blood vessels open. Lekotrienes are also important components of inflammation, and altogether it appears that whatever the real cause of migraine, the petasin isomers in butterbur have an effect in inhibiting its initiation. Add to that the potential reduction in calcium content that can cause blood vessels to become less flexible, and the argument for its effectiveness is both irrefutable and well explained.

In one example of such a double blind study that is representative of many, a group of patients given 50 mg butterbur extract twice a day for twelve weeks experienced a 60% reduction in the frequency of attacks, a reduction in the severity of the attacks they did have, and a reduction in the length of the attacks. Although the vascular theory of the cause of migraine is no longer supported, maintenance of the vascular system appears to at least reduce the likelihood of attacks.

The effect of butterbur on asthma and other allergic reactions is also well documented. This again is due to its anti-spasmodic properties and inhibitory effect on the inflammatory immune response through the inhibition of leukotriene synthesis and the consequent positive effect on the metabolism of prostaglandin. Prostaglandins also constrict vascular smooth muscle cells, regulate the mediation of the inflammatory response and constrict general smooth muscle cells. All of these can lead a to a variety of disorders cause by smooth muscle spasms in additional to urinary incontinence, such as menstrual cramps, liver and gastrointestinal disorders and asthmatic conditions.

In one study of allergic rhinitis, administration of butterbur extract appeared to result in a reduction in the histamine and leukotriene content of nasal fluids and no difference was noticed between this treatment and histamine treatment. This was a useful study because histamines causes drowsiness and butterbur can be used as a substitute for histamine without the sedative effect. A study in Germany in 1993 has shown that the stomach ulceration caused by the anti-inflammatory medications for arthritis was reduced by the administration of butterbur extract

Cetirizine is a commonly prescribed prescription treatment for allergic conditions, and studies comparing that with butterbur demonstrated them to be equally effecting in reducing the symptoms typical of allergic reactions such as sneezing, runny nose and nasal congestion. 50% of the patients in the group took each and there was no difference in results. Again it was explained by the petasin limiting the production of leukotriene and histamine, both of which are produced by the immune response and promote mucous secretions and inflammation. They also constrict airways that can be serious to asthma sufferers

These studies are simply providing scientific evidence and explanations for the tradition use of this plant for such conditions. Butterbur has been used for centuries to treat such conditions all over Western Europe, and once again the use of traditional medicine has been supported by modern investigative techniques.

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Vitanet ®, LLC

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Date: April 25, 2008 02:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pinolenic Acid - Appetite Control

Mention "pine nuts" and peoples’ mouths are apt to start watering for a taste of garlicky pesto or fragrant pilaf. Ironically, the same ingredient that is so irresistible in gourmet cooking may help curb our out-of-control appetites. But only a particular variety of pine nut—Pinus koraiensis from Korea—will do.

Source Naturals PineSlim is a Korean pine nut oil (PinnoThin™). A small-scale study suggests that PineSlim may reduce feelings of hunger by increasing concentrations of appetite-suppressing hormones. The study also suggests that a feeling of fullness is experienced 30-60 minutes after taking PineSlim. For best results, PineSlim should be taken while following the Maximum Metabolism Weight Loss Plan™ enclosed in every bottle.

Enjoying good food is part of a healthy lifestyle, but too often we don’t know when to stop. PineSlim can help by addressing one of the most basic of the dozen deep metabolic systems identified by Source Naturals as critical to your optimal health: Hormones/Metabolism.

Less Calories for Improved Health

According to a National Health and Nutrition Examination Survey, an estimated 66% of U.S. adults are overweight. A normal body fat level is one of the factors associated with many markers of good health, including insulin efficiency, healthy inflammation response, good circulation, and normal cell regeneration. One of the best ways to achieve healthy weight is by curbing the amount of calories we take in—but that’s not always easy to do. Now an ancient Asian food source may help.

Korean Pine Nuts—Traditional Asian Food

The Korean pine nut (Pinus koraiensis) has been used as a food source for centuries and is often served as a snack at social events in China. Korean pine nuts grow on evergreen trees that produce seeds (commonly referred to as nuts) that are rich in oil, particularly oleic, linoleic, and pinolenic acids.

Pinolenic acid is a fatty acid, which may influence healthy blood pressure. According to recent research, pinolenic acid also may increase concentrations of the satiety hormones glucogon-like peptide-1 (GLP- 1) and cholecystokinin (CCK).

Appetite-Suppressing Hormones

Both GLP-1 and CCK are hormones that have been found to increase satiety and suppress appetite in normal-weight humans. They are believed to work by delaying gastric emptying. Retaining food in the stomach for a longer period of time may prolong a feeling of fullness.

In a randomized, double-blind trial, 18 overweight women received 3.00 grams of Korean pine nut oil (PinnoThin™)—the same amount as one daily dose of Pine Slim—or an olive oil placebo before a carbohydrate meal. Hormone measures of CCK and GLP-1 were taken from blood samples, and subjective measures of appetite were recorded. The study demonstrated a significant increase in appetite-suppressing CCK and GLP-1 hormones at 30-60 minutes after supplementation.

Your Source for Advanced Nutrition

The plant world offers an abundance of health promoting compounds. Today exciting discoveries are emerging from research into the health benefits of botanicals. The development of PineSlim reflects Source Naturals’ commitment to manufacturing supplements on the cutting edge of nutritional science. We are glad to partner with your local health food store in bringing you nutritional resources that help you take charge of your health.

References:

Causey JL (3/28/06) Korean Pine Nut Fatty Acids Induce Satiety-producing Hormone Release in Overweight Human Volunteers, American Chemical Society Abstract, “Health Benefits of Lipids” Symposium. ABSTRACT 0117: TECH-3.

Fontana L. (2006) Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 295(13): 1577-1578. Masoro EJ. (2005) Overview of caloric restriction and ageing. Mech Ageing Dev. 126: 913-922. Sugano M, Ikeda I, Wakamatse K, Oka T. (1994)

Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. British Journal of Nutrition. 72:775-783.

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Date: April 08, 2008 08:52 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Hoodia?

1. What is Hoodia? Despite its similar appearance, the cactus-like hoodia is characterized as a succulent plant, which is a member of the milkweed family. Though there are about 20 species within the family, the active ingredient of hoodia is found only in the gordonii variety native to South Africa's vast Kalahari Desert

2. What assurances can be made that Source Naturals Hoodia Extract is authentic? Experts in succulent horticulture have helped ensure that the raw material Source Naturals uses to make Hoodia Extract is gathered from authentic Hoodia gordonii sources. From there, our supplier has an independent laboratory test the raw material, which is then issued with a certificate of analysis qualifying it as true Hoodia gordonii.

Once Source Naturals receives the certified Hoodia gordonii from our suppliers, we hold it to our own high standards and Total Quality Assurance. By putting it through stringent testing procedures in our quality control lab, we've carefully scrutinized the material. Before it ever reaches the hand of consumers, our high-quality hoodia is put through High Performance Thin Layer Chromatographic (HPTLC) analysis for authenticity, and microbiological screening for contamination, as well as other rigorous laboratory protocols.

3. Could you explain the 20:1 ratio? 20:1 refers to the "wet to dry" ratio of the whole plant to concentrated powder. Hoodia gordonii contains an abundance of excess moisture that needs to be removed in order to make an effective, concentrated powder. The process by which that moisture is removed to yield the powder is an extraction. Basically, 20 pounds of whole plant is concentrated to one pound of the high-quality powder used to make our product.

What this means is, we've made a supplement with 20 times more functional hoodia than had we ground the plant up water and all. When you buy Source Naturals Hoodia Extract, you're getting all of the usable plant parts of the Hoodia gordonii times 20, because we've packed a greater amount of the quintessential hoodia ingredients into a powerful, concentrated powder.

4. Is a 20:1 concentrated extract more effective than 1:1 hoodia powder? We at Source Naturals certainly believe so. Unfortunately, the hoodia landscape has been unnecessarily clouded recently thanks to the misinformation circulating about concentrated extracts and so-called "100%" (1:1) hoodia powder. Most of the information is highly subjective, with no studies whatsoever to support claims that so-called "pure" powder is more efficacious than 20:1 concentrated extracts.

The common selling point for those propagating a 1:1 hoodia product is the notion that "more is better" - which, when you think about it, actually benefits a 20:1 concentrated extract. Because the logic behind using the 20:1 concentrated extract is that, in supplementation, it's not practical to ingest as much of the whole plant parts of hoodia as the San did to get the potential benefits of the plant. In using the concentrated 20:1 ratio, we're able to pack 20 times the amount of usable hoodia into our Hoodia Extract. How much more could you need?

5. Where was the hoodia in Hoodia Extract grown? On an approved farm in Northern Cape, South Africa.

6. Who is our supplier? Due to obvious business considerations, we don't want to specifically name our supplier and alert competitors to our source. However you can be assured that we receive our Hoodia gordonii from one of the industry's top suppliers, who was among the first and only importers of hoodia licensed to sell and import the plant into the United States.

7. I've heard there are sustainability issues with the plant. Is it endangered? It is true that the resources for Hoodia gordonii are limited due to early irresponsibility on those seeking to exploit the plant's benefits. However, Source Naturals Hoodia Extract has been produced with environmental sustainability in mind. We've made absolutely sure that only materials safely cultivated from the stems of seedlings grown on approved farms in South Africa have been used in making Hoodia Extract, not material indiscriminately picked in the wild.

8. How should it be used? Take one to two tablets or capsules with an 8 ounce glass of water about an hour before eating a meal.

9. Why does the label warning recommend consulting your health care professional before using this product if you are taking any prescription medication? This is a standard warning included on most Source Naturals product labels because generally it's a good idea to double check with your physician if you're taking prescription medication to make sure there aren't any special precautions you need to take while on the medication.

10. Does it contain caffeine? No. There is no caffeine in Hoodia gordonii, and Source Naturals Hoodia Extract does not contain any added caffeine.

11. Are there any side-effects? There are no known negative side-effects to taking hoodia products.

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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Date: January 31, 2008 09:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Astaxanthin, a Member of the Carotenoid Family, is a Powerful Antioxidant

Astaxanthin is a member of the carotenoid family responsible for the red color of many types of algae. Being a carotenoid, it is a powerful antioxidant and free radical scavenger as well as support proper eye function.

However, such a bland statement belies the true worth of astaxanthin in its fight against free radicals. It is of particular benefit in its ability to absorb the high energy of singlet oxygen, releasing it as heat, and returning the singlet oxygen to its ground neutralized state. Singlet oxygen is a particularly harmful and reactive oxygen species of free radical that is formed in the body as part of our normal metabolism, and that contains a high level of free energy that can be used to oxidize and destroy the cells of your body.

In achieving this, astaxanthin is regarded as one of the most potent plant derived antioxidants known, being up to ten times more active than beta carotene, Lutein or its cousin canthaxanthin. So why are antioxidants so valuable to our biochemistry and what would happen if they did not exist?

Free radicals are thieves that use your body as their operating ground. They operate by stealing an electron from a molecule that comprises part of you, and in some cases when this occurs the cell from which the electron is removed is destroyed. Generally electrons go around in pairs, but occasionally an electron pair can lose one of the electrons during a chemical reaction. Many such reactions occur naturally inside the body, especially during the production of energy from blood sugars in the mitochondria, and such a molecule containing a single unpaired electron is called a free radical. Free radicals are also generated by the reactive components of many pollutants such as traffic fumes and cigarette smoke, tars and pesticides, and also by the effect of UV radiation in sunlight.

The only purpose of a free radical is to steal an electron from the first source it can find. Such reactions occur very rapidly after the free radical has been generated, and if this electron belongs to another body cell, then the cell is destroyed leading to effects such as premature aging or even cancers. Free radical oxidation of the LDL lipids that carry cholesterol around the blood causes the deposition of fatty plaques inside arterial walls that eventually become constricted or even blocked, leading to heart disease or strokes.

That is why antioxidants that destroy these free radicals are so prized, and the more of them that there are in your body then the less affect the free radicals will have on you. You will retain your youthful looks longer, and will be less liable to suffer from heart disease, cancers, circulation problems and conditions such as diabetes. Many abnormal conditions can be laid at the door of free radicals.

The stronger the free radical, the more harm it can do to you and a strong antioxidant such as astaxanthin is a very powerful weapon in your armory against them. Astaxanthin is a member of the oxygenated xanthophylls, and its high level of antioxidant power likely comes from the ketonic and hydroxyl functional groups of the ionone ring structure. It is more polar than most carotenoids, and this is a likely reason for its ability to span the cell membrane layers, with the active groups close to the hydrophilic-hydrophobic interface. They are thus more readily available at the sites where most free radicals tend to be found and provide immediate protection to the cell membrane and also to the intracellular mitochondrial membrane.

Many antioxidants destroy free radicals by donating an electron, and become oxidized themselves. Astaxanthin, however, does not do this, but instead adds the free radicals to its long double bonded chain hence avoiding oxidation and rendering it much more powerful than normal antioxidants. It is unusual among antioxidants in that it is also able to cross the blood-brain barrier, and so reduces oxidative stress that can cause neurological disorders in general, and also problems with eyesight. It can also attach itself to lipoproteins to enable it to be carried throughout the bloodstream, being available anywhere that free radicals are generated. The carotenoid is also active against active oxygen species that are responsible for inflammation.

Another property is its ability to neutralize the oxygenated free radicals formed by the photo-oxidation properties of UVA and UVB radiation. Included in these are the previously mentioned highly reactive singlet oxygen and also triplet oxygen that astaxanthin is able to neutralize without becoming oxidized. In fact reactive oxygen species in general can cause oxidative stress, and they have been thought responsible for many forms of disease and health conditions, and the powerful effect of astaxanthin in targeting many of these has led it to be regarded as highly beneficial to the immune system and to health in general.

Another benefit is the ability of the substance to help prevent the oxidation of high density lipoproteins (HDL) that are responsible for carrying cholesterol in the blood back to the liver for destruction. Free radical oxidation of HDL impairs its ability to transport cholesterol, and so decreasing the level of such free radical oxidation will by definition increase the quantity of good HDL available, and hence reduce the concentration of cholesterol in the blood. Studies have proved this to be the case, and astaxanthin supplements are very beneficial to those suffering from high blood cholesterol levels, and helps protect them from heart disease and strokes.

The substance is naturally available from a wide range of marine sources, such as lobsters (where it was first discovered), shrimp, salmon, trout and in a wide variety of red and green algae. The substance is also used as a red pigment. Carotenoids are essential, meaning that they are not produced in the human body and can only be obtained in our diets.

For that reason, the most convenient way to take it, apart from continually eating shrimp and lobster, is as a supplement. Astaxanthin is available either as a powerful antioxidant in its own right, or in combination with other substances with which it acts to provide a very strong deterrent to any free radicals that think they can freely roam your body.

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Reduce Stress at Vitanet®, LLC with proper nutrition

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Date: December 21, 2007 10:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How to Manage Migraines Naturally: Magnesium - Feverfew - Butterbur - Ginger

Before you can understand how to manage migraines naturally, it is necessary to understand exactly what they are and how certain treatments could work. It is not generally known that the word ‘migraine’ means ‘half the head’ because it frequently hurts only on the right or the left of the head of sufferer. Some people with migraines do feel pain on both sides at once, although this is not generally the case.

A migraine occurs in stages which are activated by fluctuations in the hormone content of the blood. The ‘aura’, when you see spots and flashing lights in front of your eyes, is the first stage of a migraine attack, and during this time the blood vessels in your neck and head are contracting. You could also find it difficult to concentrate and your fingers could feel cold. At this point they do not have the headache that starts when the blood vessels begin to dilate.

Rather than the contracted blood vessels slowly returning to normal, your hormones have an excessively strong reaction, and cause them to dilate rapidly and become much wider than they should be leading to a severe headache due to pressure on the nerves. Different hormones can be involves with each attack, and the range of effective natural treatments reflect this fact. During this period, your brain could swell slightly, your muscles can tense up and other things can happen to the chemical and hormonal balance of your body. That is why some herbal treatments work for some but not for others, and different people find different treatments effective for them. What works for you might not work for somebody else if their migraine has a different cause. Basically, though, migraines occur in two phases, one being associated with an excess of hormones and the other with a shortage.

It is not easy to live with a migraine since it can be completely debilitating. Some just have a severe headache, while others are affected for days at a time. The headache can become before and after the onset of the shimmering lights and other optical effects that are generated by the brain. It would certainly be useful if those prone to migraines had one or more of the possible natural remedies to hand since there is rarely time to seek to seek professional medical help once the migraine begins, and through the use of natural remedies a potentially bad attack could be nipped in the bud, and at least its effect on you reduced.

MAGNESIUM

Magnesium is common in green leafy vegetables such as spinach and cabbage, whole grains, nuts and seeds. It is an essential mineral for human biochemistry, and is also needed with calcium for healthy bone development and maintenance.

Magnesium is a muscle relaxant, and relaxes the muscles of the blood vessels helping them to relax their dilatancy that cause the migraine pain. It is also useful to help the immune function, reduces blood pressure (by the same blood vessel relaxing mechanism) and also the rhythm of your heart. Magnesium therefore provides you with many health benefits, and though the western diet is not generally deficient in magnesium, some areas can be and a magnesium-containing supplement will not do you harm.

However, particularly high dose of magnesium can lead to nausea, diarrhea, low blood pressure and many other unpleasant side effects, so do not take more than the RDA (recommended daily allowance) in your supplement. Many studies have confirmed its effectiveness in reducing the symptoms of migraine, but not all studies have been successful. However, the condition is so debilitating to so many people, that it should be tried although not in excess. Make sure, however, that your doctor is informed since it could interfere with other medication you are taking for your migraine.

Riboflavin, vitamin B-2, is also believed to useful in reducing the duration and frequency of migraine attacks, working in much the same way as magnesium. It is known that there are many cases of people who suffer from vitamin B-2 deficiency also suffering from migraines, and a riboflavin supplement is also worth trying if you are a consistent victim of this condition.

FEVERFEW

Feverfew is the best known of the herbal remedies for migraine, and has been used for centuries in the treatment of fevers, headache, migraine and other painful conditions such as arthritis. The active ingredient is parthenolide, an anti-inflammatory that is also an anti-hyperalgesic, and that would explain its effect on reducing the pain. It also blocks lipolysaccharide-induced osteolysis by suppressing the activity of a eukaryotic transcription factor protein known as NF-kappaB that can cause a number of immune response problems, including inflammatory conditions such as arthritis, hence its use to relieve that condition.

Its effect on migraines could be explained by this activity in repressing the inflammatory response to certain stimuli that could be brought about by hormonal activity. Because it must be taken for a few weeks before the actual problem arises in order to be effective against it, feverfew is not effective to treat an existing attack, but to prevent future attacks. double blind studies have proved its effectiveness in many tests, but not in all. However, if you take feverfew as a regular supplement in you diet, you might never have to try magnesium or vitamin B-2 supplements.

Some people swear by the leaves of feverfew, eating one per day which is easy way to take it. It is important, however, that you do so regularly, since it can take for up to 6 – 8 weeks for you to notice a reduction in your attacks. Don’t give up after 5 or 6 weeks, but continue, since the results will be well worth it. If you stop for a week or two you will have to start all over again. You might get a sore mouth and perhaps mouth ulcers to start with, but these will eventually go once your body is used to it.

You are probably best not to take if you are pregnant since it could cause you to abort. Otherwise, however, it has been shown to be effective in many severe cases. Feverfew is bitter, and can be used as a tea with other herbs, such as rosemary, lavender and sage. If you are taking warfarin, aspirin or other blood-thinning drugs, see your doctor first, and the same is true of NSAIDs (non-steroidal anti-inflammatory drugs). If you are taking these for arthritis, the feverfew itself might be more effective!

If you are taking feverfew as a supplement using commercially available dried leaf then the recommended dosage is around 125mg of the dried leaf. It should contain at least 0.2% of parthenolide (0.25mg/daily), although other studies have indicated that a total of 0.7 mg parthenolide a day should be taken (100mg at 0.7%). Parthenolide is unstable so don’t take it after its sell by or best by date.

BUTTERBUR

Butterbur is also useful in the treatment of migraines. The active ingredient here is petasin, a sesquiterpene ester that also has anti-inflammatory properties, all though it works in a different manner to feverfew. Here, it inhibits the activities of leukotriene generation in neutrophils and eosinophils, which indicates that it also possesses anti-allergenic properties that could help asthmatics that also suffer from migraines. It does not prevent the release of histamine, but does appear to reduce smooth muscle spasm.

You should never take the raw herb, only the extract, because it contains alkaloids that can harm you. The butterbur extract, however, is a perfectly safe supplement and found effective by many people in the treatment of migraine.

GINGER

If your migraine is at the front of the head, then you should try ginger. Unlike feverfew, ginger works on a migraine as it is occurring, and improvement can be achieved for a bad migraine within half an hour. In fact if, like many people, you can feel a migraine coming on, half a teaspoon of freshly ground ginger can stop the pain before it starts.

Many herbal treatments for migraine include a combination of some of the above remedies, and many people swear by them. However, migraine treatment is very personal, and you should use what works best for you. If you are also taking other medical treatments however, please make sure that you refer to your physician before using any others, and that includes herbal remedies or supplements.

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Date: December 18, 2007 11:43 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Eggs: An Excellent Source of Omega-3 Oils for Better Health

Eggs have many health benefits, among them being the fact they can be an excellent source of omega-3 oils that can promote better health in those that take it as a supplement. Hens fed on flax seeds are particularly high in omega-3 fatty acids, although eggs have many health benefits other than omega-3.

Most of the health benefits of Omega fatty acids are well known, although many more are being continually discovered as scientists research the uses to which the substances can be put in our bodies. Omega-3 fatty acids have long carbon chains that are polyunsaturated, i.e. contain multiple double bonds in the hydrocarbon chain. As opposed to saturated fatty acids with no double bonds. They are important components of our neurological systems and help to build up cell membranes, but are probably best known for their effect in protecting us from cardiovascular diseases. Omega-3 fatty acids can help us to maintain a healthy heart, and so enable us to live longer.

The current western diet has been changing to reduce cholesterol intake and improve our lifestyle. However, this has not all been well advised, and the resultant diet is rich in vegetable oils as opposite to animal fats, the relative levels of omega fatty acids having changed in favor of omega-6 fatty acids. These omega-6 fats are not as healthy for us as omega-3, and can lead to a thrombogenic state that more easily leads to cardiovascular diseases and blood clots. Rather than a normal omega-6 to omega-3 ratio of around 2:1, this ‘improved’ diet has increased it to anything up to 50:1.

The American Heart Association has been advocating a diet richer in omega-3 fatty acids since 1996, yet while research continues to favor omega-3, the increase in consumption of vegetable oils has continued to increase, and with it a reduction in the overall health of a nation.

Omega-3 enriched eggs have been introduced as one means of redressing the balance. Hens fed on flax seeds lay eggs with a much higher proportion of omega-3 fatty acids than normal: up to and over 150mg per egg. Such eggs also have reduced cholesterol – over 15% less, and also are higher in vitamin E, a strong antioxidant, by up to 300%.

Two of the components of omega-3 oils, linoleic acid and linolenic acid, are what are known as ‘essential’ fatty acids. The term means that they cannot be manufactured in your body, so must essentially be introduced through your diet. When the human body developed to what it is now, the consumption of fish and other oils rich in omega-3 fatty acids was a significant part of our diets, and allowed our bodies to develop the biochemistry and metabolism that it uses today.

If we now upset that biochemistry by cutting our intake of unsaturated fatty acids, our metabolism will suffer and our general health decline. This is one reason why humans should interfere with their natural eating habits as little as possible, or if we do so excessively we should use supplements to replace what we are excluding from diets that have been natural to us for countless millennia. It is dangerous now for the human race to suddenly switch to a significantly different diet without suitable supplementation, because we do not know the long terms effects of doing so.

One way to maintain a steady intake of the fatty acids our metabolism needs in order to ensure our survival is to eat eggs, and especially omega-3 enriched eggs. Of course, eggs have a lot more beneficial health effects than just omega-3. Take choline for example. This is a trimethylated compound that is important in the metabolism of fats. It is the newest official B vitamin, and is an essential component of cell membranes. It is particularly important for the maintenance of the health of your brain, and preventing many brain disorders.

It is also important in methylation, an important biochemical process, and also in the biochemical synthesis of the neurotransmitter acetylcholine. This substance is used to pass messages between nerve cells and from nerve cells to muscles, and a deficiency can cause many health problems, including heart disease and diseases of the vascular system. Methylation is a very important biochemical reaction, being used particularly in messages between body cells and is used to switch genes on and off.

Up to 90% of Americans are deficient in choline, and subject to many diseases because of it. Symptoms include insomnia, fatigue, excess fat concentrations in the blood and problems with your nerves and muscular control. It can cause liver problems and heart problems, and cause a number of brain disorders.

Choline is available in the diet from lecithin and egg yolks, and also soya beans, flax seeds, peanuts and potatoes. The typical American diet is not conducive to an adequate choline intake, and increased egg consumption can help to redress this. This is particularly true of eggs from hens fed with flax seeds, or linseed, from which the triple benefits of choline, omega-3 fatty acids and vitamin E are obtained. Just two eggs will provide you with almost 50% of your daily requirement of choline.

Some are wary about the cholesterol content of eggs, but studies have indicated that it not so much the amount of dietary cholesterol that is eaten, but saturated fats that cause the excess deposition of cholesterol in the arteries. Cholesterol is an essential part of human biochemistry, and without any we could not survive. In fact, studies have shown that eating two eggs daily can improve your cholesterol levels

Eggs are also rich in lutein, and contain more than vegetables such as spinach. Lutein is an important carotenoid that is believed to prevent age related macular degeneration, which can lead to blindness, and also prevents the development of cataracts. Eggs also appear to have anti-clotting properties on the blood, and so help to reduce the thrombogenesis of omega-6 fatty acids.

Without a doubt, eating eggs is very good for your health, and especially so if they are rich is omega-3 fatty acids. They contain a wide variety of nutrients and truly are a complete food packaged by nature. Some may prefer to stay away from eggs and miss the omega-3 benefits so there is an alternative for diets that exclude eggs. Omega-3 is available in a supplement form that one can take on a daily basis to reap the benefits omega-3 presents.

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Date: December 01, 2007 09:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: A Periwinkle Extract Vinpocetine May Promote Cerebral Blood Flow

Periwinkles form the plant genus Vinca, of which the lesser periwinkle and the greater periwinkle are the two members. They are also a form of dogbane, known for its alkaloid properties. Periwinkles are of interest to the medical profession due to their biosynthesis of a number of alkaloids that are used to protect themselves from bacteria and are also toxic to the herbivores that would otherwise eat them.

Many other plants produce alkaloids, perhaps the best known being poppy, that produces the alkaloid opium that is the precursor to heroin. The alkaloids of the periwinkle, however, have a much more beneficial use for mankind in their action on certain types of cancer such as Hodgkin’s disease, and also on the flow of blood to the brain.

The components of the periwinkle include vinblastine, which is used in the treatment of Hodgkin’s lymphoma, and it is the only plant known to produce the alkaloid, although only in very small quantities after synthetic seeding. This involves introducing modified tryptamines to the plant so that they produce the desired alkaloid, although only in quantities of 0.002% of the weight of the plant. Although small, this is still less expensive that synthesizing the alkaloid in a chemical plant rather than a biological one!

Chemists are now seeking more readily synthesizable alternative forms of the alkaloid that have the same effect, again using the periwinkle as a botanical chemical factory to provide them with a lead as to possible synthetic routes. However, it is for the application of another alkaloid of this amazing little plant that we are more concerned with here.

In addition to vinblastine, the periwinkle produces the alkaloid vincamine, a type of tryptamine that can be extracted from the leaves of the lesser periwinkle, the Vinca minor. This periwinkle has been used through the ages as an invigorating tonic and as an astringent to treat bleeding gums and sores in the mouth. Vincamine promotes the aerobic glycolysis that is essential to cerebral health.

Normal glycolysis, or the conversion of glucose to energy in the mitochondria of the cells of the body, occurs best in the absence of oxygen (anaerobic glycolysis). However, the brain produces up to and over 90% more energy through aerobic glycolysis in the presence of oxygen than through anaerobic. Hence one of the needs for such a rich supply of oxygenated blood being needed by the brain. As people grow older, or their brain tissue becomes damaged, then the supply of blood can be reduced and more and more anaerobic glycolysis is switched on. This results in an increasing loss of brain energy and hence brain function. Vincamine can reverse this effect, or at least maintain the status quo, and so enable people to maintain their brain function for longer.

It is also what is known as a vasodilator, and dilates the blood vessels in the brain allowing a greater blood flow. It is known to be beneficial in relation to tasks requiring focused concentration such as mathematical problem solving, and has also been found effective in the treatment of people with poor memory.

Vinpocetine (ethyl apovincaminate) is a derivative of vincamine, obtained by slightly modifying the molecule to produce a commercial form of the alkaloid. This possesses all of the beneficial effects of its precursor, including its positive effects on memory, believed to be due to the stimulation of serotonin production that improves the rate at which the brain can process information. Tinnitus, or ringing in the ears that has severely reduced the quality of life of so many people, can also be treated with vinpotecine.

Its vascodilation effect is thought to be through its action as a phosphodeaterase 1 (PDE1) inhibitor that results in an improvement in the plasticity of neurons. The mechanism is complex, but the end result is an improvement in the cognitive abilities of the subject. This is supplemented by the effect of vinpocetine on the calcium levels in the blood vessels. This renders them more plastic in much the same way that some anti-hypertension treatments work to reduce blood pressure by increasing the plasticity of the blood vessels by modification of their calcium levels. It can also reduce the viscosity of the blood through its action on the “stickiness” of leucocytes and so allow the blood to run more freely through the capillaries of the brain.

These effects have been demonstrated through double blind studies, and there is little doubt that vinpocetine helps to maintain a healthy cerebral circulation. So let’s have a recap on its various effects, and then finish with a summary of the conditions that the alkaloid can be used to treat or improve. The theory and biochemistry behind these effects is known, but is complex, but here are the major actions:

a) It improves blood flow by modifying the calcium content of the blood vessels and so improves their elasticity, hence allowing a freer movement of blood. In effect it helps the blood vessels to dilate easier.

b) It inhibits the enzyme PDE1 and by doing so helps to restore the elasticity of neurons in aging brain cells, allowing them to relax more and operate more effectively.

c) It promotes aerobic glycolysis, and so the rate at which the mitochondria of brain cells produce ATP (adenosine triphosphate) that is the chemical manifestation of energy.

d) It helps to maintain a good supply of glucose and oxygen in the brain to allow (c) to occur.

Not all of these may be separate effects, but the outcome is an improvement in conditions such as short term memory loss, dementia and other conditions associated with a reduction in the blood supply to the brain including Menière’s syndrome and vertigo. There is also evidence that it helps with hearing problems, macular degeneration of the eye, and fatigue.

It is a supplement that should be taken by the elderly to help with age-related memory problems, but has also been found to be beneficial in normal healthy people. The periwinkle extract Vinpocetine has been shown to have benefits, largely through an increase in the blood flow to the brain, and will be of use to anybody suffering from conditions that can be related to a deficiency in their cerebral blood supply.

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Date: November 01, 2007 09:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coconut Oil May Help Promote Healthy Thyroid and Digestive Function

Coconut is extracted from coconuts, the coconut palm often being called the tree of life and for good reason. However, its benefits were lost to America for many years due to the politics of the vegetable oil industry claiming that all saturated fats are bad. This is not based on scientific or medical fact, and coconut oil was recently rediscovered in the USA, and the health benefits enjoyed by the rest of the world are once again available to Americans.

Coconut palms grow in most tropical climates such as Southern California and Florida, the Philippines and the Caribbean. Refined coconuts oils are mass produced and much of the beneficial nutrients are lost by the refining process. Virgin coconut oil is by far the better form, though is a slower process. It is generally obtained by shredding and dry milling the meat, and then cold pressing to produce the milk. The milk is fermented for a day or so and the separated oil collected.

Such oils are analyzed to contain over 50% lauric acid and high levels of phenolic antioxidants. Much higher than from refined oils. It is said to be the healthiest oil on earth. So why did the American authorities legislate against its use? It is because of the bad press received by saturated fats and oils.

You can have saturated, monounsaturated and polyunsaturated fats. The majority of the fats and oils in our diet are composed of long chain fats and oils. The chain length refers to the length of the hydrocarbon chain, whether saturated or unsaturated. It is long chain saturated acids that are bad for your cardiovascular system, and that should be avoided. However, there are also short chain and medium chain fatty acids that are more easily metabolized by the body. Coconut oil consists predominantly of medium chain fatty acids that help to protect against heart disease and cholesterol rather than promote it.

The highest levels of medium chain fatty acids are found in coconut oils and palm kernel oils, and these are far more nutritious than the saturated long chain fatty acids found in animal fats and just about all vegetable fats. The main MCFA in coconut oil is lauric acid.

Lauric acid is generally regarded as being responsible for the vast majority of the health benefits of coconut oil. The only other source of this fatty acid other than coconut oil is in human breast milk. After absorption, lauric acid is metabolized into monolaurin that is the monoglyceride used by the human body to destroy viruses and microbes, and attack the fat coated viruses that cause such diseases as HIV. It destroys flu viruses, a number of dangerous bacteria and protozoa such as giardia lamblia.

However, let’s have a look at some of the lesser known effects of coconut oil, such as its effects on the thyroid. Anything that blocks the efficient operation of the thyroid and secretion of the thyroid hormones can lead to excess estrogen in the body that can contribute to excessive blood cholesterol. There is a body of evidence that polyunsaturated fats and oils, such as soy, can have this effect is many people. When coconut oil is used instead, the medium chain fatty acids do not have the same effect, and those that are affected frequently find that their thyroid problem is cured and their blood cholesterol reduces.

This is not to infer that all hypothyroidism can be cured through the use of coconut oil, only those cases caused by consumption of excessive amounts of polyunsaturated fats. Although this is refuted by some medical practitioners that are against the use of supplements in general, it has been supported by medical evidence.

Coconut oil is also good for the digestion, and helps the cure of many digestive problems including Crohn’s Disease. It helps to build lipoproteins, fats and bile in the liver, the latter being essential for digestion. It helps to create a much healthier digestive tract that makes for generally better digestion and more efficient use of the foods you eat. Absorption of the nutrients is maximized and you feel altogether better in yourself when you take a small amount of coconut oil daily.

You can have sugar cravings for a number of reasons, and taking coconut oil can reduce these quickly and effectively, irrespective of their cause. The medium chain fatty acid breaks down and is rapidly metabolized to glucose thus providing a source of the energy your craving is telling you that you lack. It is very useful in reducing sugar cravings without you having to eat excess sugar that can create yeast problems.

If you replace the fats you are currently eating with coconut oil, it will not only act as an appetite suppressant but can also help you to lose weight. The fatty acids in coconut are absorbed immediately and converted to energy thus reducing your immediate need for food and hence your appetite. If you eat the saturated fat in coconut oil rather than the polyunsaturated fats in vegetable oils, then you can lose weight.

Many of the benefits of coconut oil are due to the speed with which the lauric acid is absorbed and metabolized in comparison to the long chain polyunsaturated fats. It is the chain length of the hydrocarbon tail that is important here rather than the number of double bonds in that chain that determines the degree of unsaturation.

Make sure that it is virgin coconut that you use since that is the most nutritious form. Do not be misled by labels claiming the contents to be extra virgin oil, since that is a term borrowed from the olive oil industry, and there is no such thing as extra virgin in relation to coconut oil. Never use refined coconut oil since that will just as bad for you as other saturated oils. Not even ‘Extra Virgin Refined Coconut Oil’ in the mistaken belief that such a label must indicate that the oil is extra good. It does not – it simply indicates that the supplier is a charlatan deliberately trying to mislead you into paying a premium price for a useless product.

Coconut oil may promote a healthy thyroid and digestive function, and all the medical tests indicate that it does. People that use it regularly swear by it and if you have a problem that virgin coconut oil might help, then one thing is sure: it will certainly do you no harm, and all indications are that it will do you a lot of good.

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Date: October 21, 2007 07:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omnivore Vs Vegan Who Is Right?

The omnivore vs vegan argument as to who is right and who is wrong can be argued from a number of different platforms. There is the ethical issue of whether we should eat other animal life, and also the argument as which is ‘better for you’, based on arguments such as vitamin B12 is not available from a vegan diet. There is even the ‘lifestyle’ argument: does our lifestyle define our diet?

However, strictly, the only argument for or against either diet should only be made upon human biochemistry. Do both meet the needs of our biochemistry, or does one or the other lack something essential in our biochemical pathways? Obviously omnivores will lack nothing except by choice, since all foods are available for their consumption. If vegans do lack a specific chemical need, then is that available as a supplement in a form that can be effectively used in the chemistry of our bodies.

The one argument accepted by both sides is that it is essential for all animals to consume living things in order to stay alive themselves. These living thinks need not be alive at the time of consumption, but it is necessary that they eat the flesh of plant or animal life that at one time was alive and contained DNA. What that infers is that it is only vegetables that can survive on non-living tissue and this appears to be borne out in practice. No living animal known can live on inorganic matter only, but most plants can and do. Not all though, the Venus fly trap being an example.

It is easy to extend the moral problem of eating living tissue to living vegetable tissue that also contains DNA, and the argument must lie between animal and the derivatives of animals, and non-animal tissue. It has not yet been found that any organism has yet crossed the animal-vegetable divide, so the division is a valid one. That might seem obvious, but it is necessary to establish that for the argument between vegan and omnivore diets to be valid.

The consumption of protein derived from meat is not a prerequisite for size and muscle bulk, since the largest dinosaurs in the world were all herbivores, the largest being a member of the sauropod family at more than 175 tons, eclipsing the largest meat eater, the gigantosaurus at 8 tons. Thus, meat does not mean bulk. However, what has been proved is that the fastest creatures are carnivores. Hence if you want to be a top class sprinter, eat meat!

Carnivores, with their lean muscle mass and highly efficient quick use of available energy, have very short digestive tracts which are not good for digesting vegetable matter, but make best use of animal proteins and expel unnecessary mass from the body quicker. The argument in favor of the vegans is that the human digestive tract is not that of a carnivore.

In herbivores, the food takes longer to digest, and hence it remains in the digestive system longer. This means a longer alimentary canal, longer than humans have. Herbivores also move slowly, and a good example is the comparison of speed between the omnivorous chimpanzees and other small monkeys and the herbivorous gorillas and orangutans. On the one hand you have lean fast moving machines, while on the other you have large bellies and slow moving larger animals. Check out cows and sheep and compare their body fat with ours. Nor are we like herbivores.

So what are humans? Omnivores! Our teeth and intestines are those of omnivores, the teeth designed for ripping and tearing meat, and stripping leaves from trees, but also for grinding grains, and our intestines are something between the long and the short. People are able to eat and live on every type of food imaginable from brains to intestines to leaves to roots to ants and grubs.

The argument is therefore futile to consider historically. Let’s then study the advantages and disadvantages of each type of diet. Human beings are capable of life through consuming either animals or plants, or both. The argument seems, therefore, to be one of morality rather than biochemistry. However, is that really so? The vegan refusal to eat dairy products should not be taken as extremism, since the human being is the only animal species to drink milk of another species, or to use it to make other products. It is a practice born long after cattle were husbanded by humans for food. The problem with eating animal products lies not in the meat itself, but in the fat. Animal fat is saturated, which means that the fat molecule has no active double bonds in the chemical structure that can be used to break the fat down.

Animal fat also contains cholesterol, yet we cannot survive without cholesterol. It is the human band aid, used by the body to patch up damage to the cardiovascular system. Only, sometimes, too much is laid down and the arteries get blocked. However, many vegetable products have more saturated fats and cholesterol than many animal products, so a balance is called for. The unsaturated fats and oils for humans are said to be derived from seeds, such as flax seed and fish, especially oily fish. These are the Omega-3 oils. Although they can be obtained from some seeds and nuts, it has been proved that the best come from oily fish, such as wild salmon, mackerel and sardines.

The B vitamins are essential for life. The best sources are animal sources, though you get them from some vegetable sources such as brewers years (who eats lost of that?) and others, but animal sources are the best.

Also, there is no evidence to suggest that vegans live longer than omnivores. In fact all of the evidence indicates that a middle road is the best. For human beings the healthiest diet includes both meat and vegetable tissue. The best solution to good health is neither vegan nor carnivore. Nor is it traditional vegetarian, since it is the dairy products that cause many of our dietary products.

Studies of the biochemical pathways have demonstrated that all chemicals need to sustain healthy human growth and life are not available from a classic vegan diet. Some animal protein and B vitamins are essential that cannot be obtained form a normal vegan diet. It is possible, however, to maintain life by means of supplements.

However, for the healthiest form of human life, our biochemistry, history and physiology indicate that there is a balance somewhere between the extremes of both views that is right for us, and that either diet can be sustained with appropriate supplementation based upon what is missing from one diet or the other.

So, omnivore vs vegan. Who is right: both are right if they also supplement any nutritional deficiencies in their diet with vitamins and minerals that may be lacking from one diet or the other.

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Date: May 31, 2007 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Papaya- May Be A Fountain of Youth

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Date: May 11, 2007 10:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Breast Cancer and Natural Supplements

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Date: April 25, 2007 03:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Do you experience muscle pain and inflammation?

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Date: April 20, 2007 12:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Learn about Bone Health!

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