The elevated levels of insulin found in many people with obesity can elevate their risk of breast cancer, but new studies show that omega-3 free fatty acids can help mitigate this risk. Too much insulin can increase Akt and Erk1/2 phosphorylation, but omega-3s can help to reduce this effect. Likewise, omega-3 free fatty acids were able to cut down proliferation of MCF-7 cells. The research sheds some light onto why omega-3s appear to reduce the risk of breast cancer, although more research is needed.

Key Takeaways:

• While having a high insulin level is considered a significant factor in one having breast cancer while obese, omega-3 fatty acids reduce the risk of breast cancer.
• The researcher wanted to explore whether omega-3 free fatty acids (FFA) do regulate the signaling pathway of insulin in order to prevent breast cancer.
• According to the findings it is suggested that omega-3 free fatty acids (FFA) reduce the proliferation of breast cancer cells mediated by insulin and insulin activated phosphorylation.

"Researchers found a link between consumption of omega-3s and reduced breast cancer risk by lowering insulin levels. The study, which was published in Nutrition Research, tested the ability of omega-3 free fatty acids (FFAs) to reduce insulin-induced breast cancer cell proliferation."

Read more: https://www.naturalnews.com/2019-03-26-omega-3-can-reduce-high-insulin-levels-breast-cancer.html

Because essential oils can relieve pain and increase cell energy production, researchers believe that these essential oils like lavender, capsicum, and peppermint, can be used to treat fibromyalgia. When one is afflicted with fibromyalgia, he will always have chronic pain, constant fatigue, and regular changes in mood. These symptoms have only few ways to treat them. It has been noted that some supplements, of which essential oils are among them, can be used to treat these symptoms of fibromyalgia. This is because they are already being used to relieve health problems that are similar to fibromyalgia. One example of these is lavender oil. This is used in aromatherapy as a relaxing compound. And it regulates mood responses and the central nervous systems, which symptoms are related to fibromyalgia. Another of these essential oils is peppermint oil. Because it alleviates the pain muscles face by chronic stress and increases stamina, it is a good remedy for fibromyalgia.

Key Takeaways:

• People who are down with fibromyalgia experience chronic pain, constant fatigue, and changes in their mood that is sharp and treatments for these symptoms are few.
• Lavender essential oil is used often in aromatherapy because it is a relaxing compound which is involved in regulating the mood and the nervous system.
• Many participants who participated in a 2012 study reported that they slept better when they slept in a room filled with the vaporized essential oil.

"Given these beneficial effects, researchers believe that the oils drawn from capsicum, lavender, and peppermint could be potential therapies for fibromyalgia."

Read more: https://www.naturalnews.com/2019-04-02-capsicum-lavender-and-peppermint-essential-oils-relieve-fibromyalgia-pain.html

There's a lot of buzz about curcumin these days and for good reason. A recent study published in The Journal of Applied Physiology suggests that it can help to improve athletic performance in heart failure patients. Other research has shown that it could reduce muscle loss in individuals with heart disease. Due to its potent antioxidant and anti-inflammatory effects properties, it also can be a very effective post-workout supplement. In fact, researchers found that people that consumed one gram of curcumin twice daily had decreased muscle injuries and less pain in their lower legs.

Key Takeaways:

• To add to the growing research on curcumin, a new research has shown that taking curcumin can improve athletic performance in people having heart failure.
• The study was published in the Journal of Applied Physiology and it showed that persons taking curcumin have enhanced muscle function and increased exercise capacity.
• Curcumin, which is the active ingredient in turmeric, has for a long time been used in Asian medicine to relieve symptoms of digestive problems and skin wounds.

"For the study, researchers from the University of Nebraska Medical Center looked at the effects of curcumin on a mouse model of heart failure with reduced ejection fraction. The compound is known to promote activation of Nrf2 protein, which regulates the expression of antioxidant enzymes that prevent and repair damage from oxidative stress and boost exercise performance."

Read more: https://www.naturalnews.com/2019-03-18-curcumin-improves-muscle-function-exercise.html

Green tea is a very versatile health food with many different benefits. Green tea can help regulate your weight and your blood sugar. The caffeine and l-theanine it contains can help improve brain functioning and reduce anxiety symptoms. Green tea bags can be used to repair damage inflicted on your skin by free radicals and UV light. Green tea’s powerful anti-inflammatory effects may even help to reduce the damage to the body and brain from conditions like cancer, Alzheimer’s and Parkinson’s disease.

Key Takeaways:

• The aging and potentially deadly effect of UV radiation is said to be lessened when the affected are also drinking green tea.
• To promote eye skin elasticity and remove unsightly eye bags, place boiled, decaffeinated, organic, green tea bags that have been allowed to cool, on the appropriate area.
• Data suggests that green tea facilitates the function of neurotransmitters in the brain and also boosts metabolism, thereby promoting healthy weight loss.

"“Green tea has been a favorite drink of health enthusiasts for decades,” Dr. Ellen Kamhi, Ph.D., author of the”Alternative Medicine Definitive Guide,” tells Newsmax. “It has also been well studied for its health promoting effects on skin. It’s high in compounds called polyphenols which help eliminate free radical damage and rejuvenate aging skin cells."

Read more: https://www.newsmax.com/health/health-news/green-tea-health-benefits/2019/03/19/id/907629/

Potassium is vital to the most basic functions of your body, including muscle function and your cells’ ability to take in and release fluids and nutrients. During pregnancy, it becomes even more important by helping to reduce fluid retention and fight unpleasant symptoms like restless legs and cramped, uncomfortable muscles. A potassium deficiency, also known as hypokalemia, is usually the result of a rapid, major loss of fluids, and can product symptoms such as soreness, cramps, stiffness and spasms in the muscles, breathing and digestive problems and more.

Key Takeaways:

• The vital nutrient, potassium regulates fluid and other minerals in the human body's cells.
• Potassium also aids in the regulation of blood pressure, the contractors of muscles and the transmission of electric nerve impulses.
• A severe lack of the mineral can lead to exhaustion, vomiting, nausea and constipation.

"Potassium helps reduce fluid retention, combats electrolyte imbalance, and eases restless leg syndrome and cramps, all of which are major causes of discomfort during pregnancy."

Read more: https://www.onegreenplanet.org/natural-health/potassium-and-pregnancy-everything-you-need-to-know/

Turmeric is hailed for its properties in helping to regulate blood sugar, fighting inflammation and infection, and helping cancer patients. In helping cancer patients, turmeric is able to affect cancerous cells without harming the non-cancerous cells. DYRK2 is inhibited by the turmeric, keeping the cancer from growing. Carfilzomib used with turmeric helped with cancer cell death with minimal affect to the healthy cells. Turmeric also promotes angiogenesis, which stops the growth of new blood vessels which support the growth of tumors, and also doesn't allow development of adhesion which leads to metastasizing of cancers.

Key Takeaways:

• Turmeric was first cultivated in the SouthEast Asia and India. It is a kitchen spice that is revered for its ability to fight inflammation and regulate blood sugar.
• New research shows that turmeric has even more potential. Due to its active compound, curcumin, research has shown that it could be used to fight cancer.
• A new study conducted by researchers in United States and China showed that turmeric can successfully be used to target several aggressive forms of cancer.

"The team used cutting-edge X-ray crystallography to obtain 3D images – in which curcumin could distinctly be seen binding to the enzyme at the atomic level."

Read more: https://www.naturalhealth365.com/curcumin-cancer-cell-2659.html

We're constantly met with over-the-counter supplements loaded with chemicals and preservatives that promote claims of being able to shrink your waistline, but what if there were more natural options? Consuming ginseng helps regulate your blood sugar levels, as well as boost your metabolism. Garlic is almost a magical herb in how it is able to help you fight off cravings due to your body being able to sustain levels of fullness for longer periods of time.

Key Takeaways:

• A popular Asian herb, ginseng may help maintain blood sugar levels and aid in dampening food cravings.
• Garlic may also suppress appetite triggers and aid in burning off calories already present.
• Data suggests that the component, carvactrol, found in oregano oil, may aid in weight loss.

"Those 7 days or 1-month weight loss challenges cannot give you a long-term result."

Read more: https://timesofindia.indiatimes.com/life-style/food-news/heres-4-magical-herbs-that-can-help-you-lose-weight-faster/articleshow/68283825.cms

Curcumin, the active ingredient in turmeric, can have benefits for mental health on top of its many benefits for cardiac and joint health and inflammation. Curcumin is believed to help reduce neuroinflammation — and the cytokines that help cause it — and moderate cortisol levels within the brain, while achieving more balanced levels of dopamine and serotonin. These actions may explain why a 2015 study indicates that turmeric supplementation can substantially improve the effectiveness of antidepressants in many people.

Key Takeaways:

• The main compound form in turmeric, curcumin, has been found to help in many types of ailments that range from diabetes, to cancer and inflammation.
• Curcumin makes turmeric a superfood by adding aiding in mental health to the list of health benefits that it can be used to cure for.
• Australian researchers have found that curcumin can help in curing depression and anxiety when they involved 123 participants in a curcumin treatment and a placebo.

"Curcumin regulates levels of dopamine and serotonin in the brain, and it also decreases the markers of neuroinflammation, which is significant when you consider that inflammation contributes to mood disorders."

Read more: https://www.naturalnews.com/2019-03-11-curcumin-rich-turmeric-can-help-ease-depression-and-anxiety.html

Hemp oil is a type of CBD oil that is extracted from the hemp plant and has only trace amounts of THC, the psychoactive substance in marijuana. Because the THC levels in hemp are so low (and legal), it does not give you that high affect. Hemp is high in omega-3 and omega-6 fatty acids and is a known anti-inflammatory. Some claim the fatty acids in hemp oil alleviate anxiety, physical, and emotional pain linked to PMS and other conditions. According to some research, the polyunsaturated fats in hemp oil may decrease cholesterol levels, making it a heart healthy substance. However, most hemp studies have not been conducted on humans and the substance itself has not been thoroughly tested for heavy metals, plastics or pesticides. For these reasons, it may be best to wait until hemp is more closely regulated before making it a part of your daily routine.

Key Takeaways:

• Many persons seem to have taken on the trend that CBD oil is good for them because it has many health benefits.
• Many persons think that hemp oil, the sister to CBD oil is good for them, and believe the claims that it is good for anxiety and sleep.
• The difference between hemp and marijuana is that marijuana contains high amount of THC, the stuff that makes one high in cannabis, while hemp contains low amount.

"Not only does hemp oil not have any real health benefits, but it may contain stuff that's actually bad for you."

Read more: https://www.womenshealthmag.com/health/a26630156/hemp-oil-benefits/

A recent study took pregnant rats who were suffering from gestational diabetes, and they gave them propolis to see if it had a beneficial impact on regulating their glucose levels. The results showed that propolis did, in fact, help regulate blood sugars, and it also helps in several other areas as well. Taking propolis consistently can also help protect you against hypertension during your pregnancy, as well as promote faster wound healing which is extremely important in diabetic patients.

Key Takeaways:

• Researchers from institutes of higher learning in Malaysia and Nigeria have undertaken study regarding the risks of pregnant women with diabetes.
• Diabetes, which affects more than 600 million people worldwide, can have deadly effect on the kidneys and the cardiovascular system.
• Pregnant women with diabetes risk cognitive impairment to their newborns should their sugar levels not be maintained.

"Their study, which was published in BMC Complementary and Alternative Medicine, showed that the superfood propolis not only improves pregnancy outcomes but also placental oxidative stress."

Read more: https://www.naturalnews.com/2019-02-26-diabetic-pregnant-women-should-take-propolis.html

We're all well aware of the digestive benefits associated with high amounts of fiber in out diets, but research is now showing that increasing your fiber can actually reduce one's vulnerability to breast cancer. Problems with insulin and glucose levels are often a primary culprit in the development in breast cancer, and fiber actually has the ability to regulate glucose levels. Since glucose levels remain more stable after regularly taking in fiber, the odds of developing breast cancer can be reduced.

Key Takeaways:

• Limiting sugars, grilled food, certain carbs, red meat, and fried food are dietary restrictions that may help prevent cancer.
• There are two types of fiber that are defined based on their ability to be digested by the gut.
• Both types of fiber assist with hormonal regulation and can assist with the prevention of breast cancer.

"On its way out, insoluble fiber brushes the insides of the colon. This helps eliminate harmful substances so that they don’t accumulate in the body."

Read more: https://www.naturalnews.com/2019-02-28-fiber-keeps-breast-cancer-at-bay.html

Who doesn't like basking in the rays of sunshine on a nice summer day? Since sunlight has the natural ability to raise serotonin levels, it naturally has the ability to regulate and improve your mood. Not getting enough exposure to sunlight on a regular basis can actually lead to the same harmful side effects that are associated with obesity and smoking. UV exposure is especially important for those who are impacted by seasonal affective disorder (SAD), even if it is received in an artificial setting.

Key Takeaways:

• UVB radiation from sunlight is what causes the human body to synthesize critical vitamin D.
• Vitamin D propels genes in the human body that aid in regulating the immune system and in releasing neurotransmitters in the brain.
• One of the neurotransmitters directly impacted by vitamin D is serotonin, the lack of which is highly implicated in an array of mood disorders.

"A recent study, found that underexposure to sun carried significant risks, similar to smoking, obesity, and being sedentary."

Read more: https://www.yahoo.com/entertainment/5-reasons-sunshine-totally-good-health-102319967.html

Traditionally, melatonin supplements have been taken to induce a full night's rest, as well as aiding individuals in easing into a deep slumber. Since melatonin is a natural angiogenesis inhibitor, it actually has the ability to reduce the significance of tumors that are located within the body. The process of inhibiting angiogenesis is an essential part of treating cancer patients because it helps target the cells with oxygen. This helps regulate cell migration as well as invasion.

Key Takeaways:

• The Iranian study which was published looked at the molecular anti-angiogenesis pathways that melatonin uses and the mechanisms that were at play in different forms of cancer.
• Melatonin is a hormone that the body produces at the pineal gland and from research it has been found that it possesses diverse biological actions, including antitumor.
• Since the increase of angiogenesis is a definite sign that a tumor is progressing, when melatonin exerts its anticancer effect, it inhibits angiogenesis.

"A team of researchers from Iran suggests that melatonin has powerful anticancer properties."

Read more: https://www.naturalnews.com/2019-02-27-why-melatonin-is-a-powerful-anticancer-indolamine.html

The sea buckthorn oil serves many purposes such as treating varied health problems. The oil is made from the berries, seeds, and leaves of the plant. The antioxidant flavonoids within the oil can help the immune system as can the amount of Vitamin C contained in the oil. This oil can also help the heart by lowering cholesterol and blood pressure. The carotenoids contained in the berries can also assist with anti-aging, wrinkles, and skin moisture. Another study suggested that buckthorn oil may help to regulate blood sugar, therefore helping with diabetes, and yet another study showed that omega fatty acids were found in the oil too, which can help with liver disease prevention.

Key Takeaways:

• Sea buckthorn has medicinal properties that rival most of today’s natural and conventional drugs and treatments.
• Sea buckthorn is packed with powerful flavonoids and vitamin C, which have potent antioxidant and immune boosting properties.
• According to one study, daily intake of sea buckthorn contributed to decreased levels of LDL cholesterol, triglycerides, and blood pressure.

"The high antioxidant content found in sea buckthorn oil can help protect your body from the harmful effects of free radical damage and oxidative stress."

Read more: https://www.naturalnews.com/2019-01-28-sea-buckthorn-oil-is-such-a-powerful-remedy.html

Immunosenescence is a condition that affects people as they age. The condition causes a decline in the immune system response and its ability to fight off infections and diseases. There is new evidence that suggests that eating the Reishi mushroom is one beneficial way to boost the immune system and ward off this condition. The delicious mushrooms are easy to use in the kitchen, making it even easier than you thought to add them to your diet.

Key Takeaways:

• With age and the passage of time, many people become susceptible to immunosenescence but reishi mushrooms have been shown to address this condition.
• Reishi mushrooms can help fight immunosenescence can helping to regulate and support the immune system when it is aging, reducing inflammation and preventing heart disease.
• Traditional Chinese medicine practitioners call the mushroom the “mushroom of immortality” because it has healing and antiviral properties which make it ideal for treating various health problems.

"According to research data, the potent mushrooms can also be used to boost the immune system."

Read more: https://www.naturalnews.com/2019-01-19-reishi-strengthens-immune-system.html

The vast majority of women will suffer from common PMS symptoms like cramps, insomnia, headaches, anxiety and mood swings. Roughly five percent of women will suffer more serious symptoms — known as premenstrual dysphoric disorder — involving anger and depression. However, studies suggest that women who take a daily magnesium supplement suffer from less severe PMS symptoms, possibly because magnesium helps promote higher levels of gamma-Aminobutyric acid (GABA), a neurotransmitter which helps regulate sleep. Women who experience exhaustion as a central PMS symptom are particularly likely to need more magnesium.

Key Takeaways:

• Seventy-five percent of women suffer from PMS at some point during their life.
• Magnesium research suggests that it can help with restful nights sleep, reduce the symptoms of pain and tiredness, as well as migraines and mood swings.
• Research suggests that individuals who received a magnesium supplement saw improvement with PMS symptoms and lowered depression and anxiety.

"According to PubMed Health, during this time, some women feel a wide range of physical discomforts, such as abdominal pain, abdominal cramping, backache, headaches, bloating, weight gain, breast tenderness, possible sleeping issues and digestive discomfort."

Read more: https://www.dailymail.co.uk/health/article-6697649/Is-magnesium-secret-ending-PMS-Vitamin-eases-headaches-cramps.html

Broccoli can really help your body’s ability to expel harmful toxins that you ingest or breathe in According to recent research, post-menopausal women who ate lots of cruciferous vegetables like broccoli showed a substantially lower risk of breast cancer, perhaps because broccoli improved their livers’ ability to detoxify their bodies. Likewise, a 12-week Johns Hopkins University study of almost 300 people in a heavily polluted part of rural China found that broccoli made their bodies much more efficient at excreting dangerous compounds like benzene and acrolein.

Key Takeaways:

• One major study found that post-menopausal women who ate lots of broccoli and other cruciferous vegetables had a lower chance of breast cancer.
• A 12 week Johns Hopkins University study in a heavily polluted region of China found that broccoli improved excretion of harmful chemicals like benzene and acrolein.
• Broccoli can also promote better cardiac health, regulate your blood sugar and improve your immune system.

"These detoxifying benefits of broccoli can be attributed to the presence of phytonutrients called glucoraphanin, gluconasturtiian, and glucobrassicin."

Read more: https://www.naturalnews.com/2019-02-12-broccoli-is-one-of-the-best-detoxifying-foods.html

Mushrooms have long been associated with alternative medicine. The Chinese led the way to mushroom use for treatment of infertility, cancer, and PTSD. Nowadays, people are also turning to mushrooms to help keep bodies healthy during stressful times. Medicinal mushrooms can also regulate cortisol levels. When people have difficulty falling asleep the reishi mushroom can help with that. Chaga can help reduce inflammation. The lion’s mane mushroom can help lift cognitive function during moments of stress.

Key Takeaways:

• Mushrooms have a long history of use in medicine that dates back to the Chinese who used it as treatment for post-traumatic stress, cancer, and infertility.
• Stress in individuals can make them unable to fall asleep and this inability can increase to more stress so the circle continues. Reishi mushroom is effective against this.
• Reishi mushroom contains nutrients like Calcium and Magnesium, and also antioxidants that help to improve spiritual potency, well being and longevity.

"Something that all medicinal mushrooms have in common is that they possess adaptogenic properties, which primarily involves regulating cortisol levels."

Read more: https://www.naturalnews.com/2018-12-16-medicinal-mushrooms-keep-you-strong.html

Turmeric has numerous health benefits. One such benefit is it has anti-inflammatory properties due to the presence of curcumin. Therefore, it is no surprise that it helps joint health. The presence of curcumin can also be linked to promoting healthy ageing. It also can help regulate cholesterol levels and supports cardiovascular health. Turmeric can also be linked to helping people lose weight. There are also studies that it can support brain function including improving your memory.

Key Takeaways:

• Several health concerns such as Alzheimer’s have inflammation as its root cause and turmeric can cure them due to its having curcumin, an anti-inflammatory compound.
• Because turmeric can prevent inflammation this makes it ideal for regulating blood cholesterol. The main culprits behind rise in blood cholesterol are inflammation and high blood sugar levels.
• Turmeric saves as a protective herb, protecting the heart from heart disease and improves the lining of the blood vessels as well.

"Turmeric is a spice that has served mankind since ancient times. The herb is now being increasingly used in the form of a supplement as well."

Read more: https://dailywellnesspro.com/9-health-benefits-of-turmeric

Tocotrienols, a chemical grouping that belongs to the vitamin E family, has been shown by research to have efficacy in reducing blood sugar levels and inhibiting bone loss. The most recent research came in the form of two studies, both of which made use of a tropical fruit, known as the annato. A pre-diabetic state and osteoporosis was induced in rodent subjects for both of the studies. One of the studies, conducted in Malaysia, showed that the rodent subjects had better parameters for a number of metabolic syndrome indicators, such as fasting blood glucose and triglycerides. In the case of the Malaysian study, the rodents either received a dose of tocotrienols commensurate with normal human supplementation or a diet stripped of tocotrienols. A Texas-based research study compared the tocotrienols with Metformin, a commonly prescribed diabetic medicine. Results showed that the tocotrienols in higher doses was better than the medicine in instituting bone growth. A third study, also in Malaysia, used human subjects with type 2 diabetes. Markers for the human subjects were also improved for the subjects that consumed tocotrienols.

Key Takeaways:

• There are so many people in the world today that are suffering from diabetic disorders.
• Understanding how to use vitamins to combat your disease is a great method to use.
• You should do everything in your power to reduce the risk of losing density in your bones as you get older.

"Studies have shown that tocotrienols may help inhibit bone loss and regulate blood sugar levels. The tocotrienols used in the studies were derived from the red-orange tropical fruit known as annatto."

Read more: https://www.naturalnews.com/2018-11-30-vitamin-e-lessens-bone-loss-risk-due-to-diabetes.html

No nutrient is quiet as important as Vitamin C. It's a power-packed immune-boosting powerhouse that is found in oranges and other citrus fruits, and many other foods. When the body gets an adequate supply of Vitamin C, it thrives in more ways than one and you will look and feel your best. So while there are many nutrients that your body needs, it is important to put special emphasis on vitamin C and the positive attributes it can bring into your life.

Key Takeaways:

• As we enter the cold and flu season, Vitamin C is indispensable. It is an immune booster and contains lots of antioxidants that are beneficial to the body.
• Vitamin C works with a good number of regulatory enzymes as a potent antioxidant and cofactor. It also kills off bad bugs.
• To counteract the cell damage that getting old is associated with, people are asked to take Vitamin C for better health and longevity in old age.

"A very interesting study from last month demonstrated that in diabetes-induced rats who showed depression-like behavior, giving vitamin C helped with the depression, especially if blood sugar and insulin levels were also regulated."

Read more: https://www.mindbodygreen.com/articles/vitamin-c-health-benefits-side-effects-and-dosing

Hemp seeds tend to get a bad rep due to the stigma surrounding the recreational use of marijuana, but there are several medicinal benefits that hemp seeds can provide that you may not be aware of. For instance, hemp seed oil has been found to counteract the negative effects brought on by Rheumatoid arthritis. The anti-arthritic properties found in hemp seeds have the ability to actually attack the cells that cause the Rheumatoid arthritis, giving the patient some relief.

Key Takeaways:

• Hemp seeds are one of the best sources of protein, especially if you are a vegetarian.
• Hemp seeds contain an amino acid called arginine, which can lessen the symptoms of heart disease.
• Hemp seeds can reduce your appetite, regulate your blood sugar, and promote good digestive health.

"Arthritis can be one of the most painful condition as it affects all the joints of the body and hinders the day to day life."

Read more: http://heraldoffashion.com/5-benefit-of-hemp-seeds-that-you-probably-didnt-know/

Almonds are an extremely versatile food. They can be added to just about any food. It also provides great benefits for your heart, stomach, and brain. Almonds can decrease one's heart attack risks. It can also regulate one's blood sugar and improve memory. In addition, ingesting almonds long term can aid healthy gut microbiota and it can help prevent cancer. They can also help a person keep a healthy weight, and almonds can even extend a person's life.

Key Takeaways:

• Almonds are beneficial to the heart since they are rich in polyphenols and vitamin E that work as antioxidants and prevent free radicals from accumulating.
• Insulin resistance, especially in Type 2 diabetes patients, has been associated with magnesium deficiency
• Eating almonds can promote better memory by increasing the production of the neurotransmitter acetylcholine in the brain.

"Eating almonds is beneficial for heart, brain, and stomach health and function."

Read more: https://www.naturalnews.com/2018-10-30-almonds-are-good-for-your-heart-brain-and-stomach.html

There are a variety of different ways in which you can reduce the chances of your child having allergies. If you simply take fish oil while you are pregnant, your child will have a lower chance than others of developing allergies. Some people are skeptical of this and honestly, not many people can blame them. However, there have been a lot of clinical studies done and it is being proven that it is in fact very true.

Key Takeaways:

• A study on the relationship between taking of fish oil by mothers during pregnancy and allergy in children shows that allergy risk is reduced when mothers do this.
• Docosahexaenoic acid (DHA) is an omega-3 fat which regulates brain function and also regulates immune responses.
• Although the study showed a positive relation between fish oil in pregnancy and reduced allergy in children, it did not state the ideal doses for mothers.

"They followed up on children who were born to mothers who took fish oil supplements containing DHA and those who did not for six years. The researchers found that at the age of one, children of mothers who had consumed a large amount of fish oil in pregnancy had less allergy to egg."

Read more: https://www.naturalnews.com/2018-09-12-taking-fish-oil-while-pregnant-found-to-reduce-allergies-in-children.html

According to recent research, people that consume a lot of processed sugars run a greater risk of developing Alzheimer's disease. What happens is the high sugar levels damage a major enzyme called macrophage migration inhibitory factor. Previous research has already shown that people with diabetes are more likely to develop this disease. However, the most recent research looked at brain samples of people with and without this disease and the process of glycation. It showed that glycation damages the essential enzyme which regulates insulin and the immune response.

Key Takeaways:

• High sugar levels damage a major enzyme called macrophage migration inhibitory factor or MIF which regulates insulin and the immune system.
• Recent research shows two brain samples with and with out Alzheimer's disease and the process of glycation with in the body.
• The processed sugars showed to damage the enzyme MIF which therefore resulted in greater risk of having Alzheimer's disease.

"Research has found that a high intake of processed sugar can raise the risk of Alzheimer’s disease."

Read more: https://www.naturalnews.com/2018-09-12-eating-too-much-processed-sugar-increases-your-risk-of-alzheimers.html

Vitamin B1, which is also known as thiamine, is a vital nutrient when it comes to human nutrition. In fact, Thiamine is a vital nutrient for the human nervous system. Within this capacity, it moderates appetite, prevents memory loss and reduces the possibility of nerve inflammation.

Thiamine has the intrinsic capacity to aid in maintaining energy levels, because its used at the cellular level throughout the body. That said, it stands to reason that a Thiamine deficiency can show itself as a significant lack of endurance and in a tendency to exhaustion. Besides its profound effect on the central nervous system, Thiamine also has a decided effect on the gastrointestinal system. Fortunately, besides supplementing with vitamins, Thiamine is amply available in natural foods. High protein sources include lean pork, fish and dry roasted soybeans. Vegans can get their thiamine on too. Besides soybeans, the nutrient is available in good quantity in wheat bread, asparagus and green peas.

Key Takeaways:

• Vitamin B1 also helps to regulate appetite and improve memory, besides being of use to the digestive system.
• Thiamine boosts energy at the cellular level, which is why a severe lack of the nutrient can lead to exhaustion and a lack of endurance.
• Lean pork, fish, green peas, roasted dry soybeans, wheat bread and cooked asparagus are all good sources of Thiamine.

"Vitamin B1 also called Thiamine, helps in maintaining cellular functions and boosts the functions of the central nervous system."

Read more: https://crazytalker.com/vitamin-b1-thiamine/

We often separate who we are into two separate parts, specifically body and mind, acting a if we are some odd hybrid creature. But, the truth is that the brain is as much a part of the body as the fingers, muscles and hair are. We all expect our diet to affect our waistline, and strength, our energy and our hair's luster, or lack thereof. In reality, since our brains are as much affected by our diet as any other part, it stands to reason that our mind's ability to handle stress, emotions and mental load are very much affected too. All of which is born out by data which shows that diets that are imbalanced and overloaded with sugar, unhealthy fats, and chemical additives are apt to contribute to disease symptoms, like ADHD, depression and anxiety.

When the body lacks specific nutrients, like sufficient protein, it can hamper the body's ability to create needed brain chemicals that aid in our ability to handle emotions and stress. In fact, the brain is comprised of a great deal of fat. So, healthy a diet that has sufficient good quality fatty acids is important fro brain health. Brain health and stamina is affected by an array of nutrients that come from food, including magnesium, vitamin B12, zinc and vitamin D. Their lack can cause or hasten mood and behavior shifts that can become problems.

Key Takeaways:

• How levels of omega-3 fatty acids can lead to depression, anxiety, and attention difficulties.
• If you are a vegetarian or a vegan and you are suffering from depression, you may want to make sure you are getting enough Vitamin B12.
• Foods rich in protein, including nuts, meat, and eggs, contain amino acids which regulate your serotonin levels.

"But the foods we eat also play a role in how we feel mentally as well, and an imbalanced diet can mess with our heads just as much as our stomachs."

Read more: https://www.bustle.com/p/how-nutrient-deficiencies-can-affect-your-mental-health-11194369

We've all heard about how cortisol levels can increase fat around the abdomen, but how do we lower these levels that are dangerous to our overall health? Reducing your stress levels is one of the main ways that you can decrease the presence of cortisol in your body. You can do this by finding ways to regulate your thinking into a more stabilized fashion such as learning how to participate in deep breathing and other meditative practices.

Key Takeaways:

• Ensuring that you get adequate sleep can significantly reduce stress levels, as well as the amount of cortisol you're storing.
• Find ways to identify triggers that make you stressed out in order to help reduce stress levels.
• Be sure to get enough exercise to experience the benefits of it while not going overboard.

"It’s important for helping your body deal with stressful situations, as your brain triggers its release in response to many different kinds of stress."

Read more: https://www.healthnutnews.com/11-natural-ways-to-lower-your-cortisol-levels/

Are you looking to bolster your brain health in a natural way? Bacopa might be able to help you. It offers many benefits to the brain. For starters, it can make you more durable when dealing with stress. It also can be used to regulate your neurotransmitters. Not only does it improve blood flow to your brain, it also inspires new formations of nerve cells. Finally, it has powerful effects on depression, inflammation, memory and brain elasticity.

Key Takeaways:

• Bacopa is a potent and natural supplement that can bolster brain health.
• Bacopa increases stress resilience, regulates neurotransmitters and improves blood flow to the brain.
• Bacopa also promotes the growth of new nerve cells and fights inflammation and depression.

"Together, these compounds make up eight percent of bacopa’s dry weight. Bacopasides are believed to play essential roles in the benefits that bacopa provides."

Read more: https://www.naturalnews.com/2018-08-13-take-bacopa-every-day-to-boost-mental-clarity.html

Avocados are an incredibly nutritious food rich in fiber, potassium, a plethora of vitamins and healthy fats like oleic acid. Avocados have a lot of uses in protecting against degenerative diseases. For example, the healthy fats in avocados can lower cholesterol. Avocado also contains compounds that can help to control blood sugar, protect your joints from arthritis and reduce the impact of oxidative stress on your liver. Avocados are also tasty and satiating, which can be useful qualities for helping people stick to diets and keep their weight under control.

Key Takeaways:

• Avocados are rich in fiber, potassium, a wide variety of vitamins, and healthy fats like oleic acid.
• The healthy fats in avocados can help reduce your bad cholesterol, and with it your heart attack risk.
• Avocados also contain various compounds that promote liver health, regulate blood sugar and protect your joints.

"Without a doubt, the avocado is a fruit that needs to be part of everyone’s diet."

Read more: https://www.naturalnews.com/2018-08-02-avocados-are-one-of-the-simplest-ways-to-prevent-degenerative-disease.html

Pecans originate from the Midwestern part of the US, and their health benefits are shown to be quite substantial. Pecans are high in vitamin E, which causes them to have large amounts of antioxidants properties. They can also help clean and regulate oxidation processes in order to help contribute to the prevention of various cancers. Studies have indicated that consumption of pecans may also have the ability to help those with liver damage, but it has not been proven in human subjects as of right now.

Key Takeaways:

• Pecans are rich in nutrients that can help people avoid cardiovascular disease.
• The phenolic acids in pecans are key in preventing cell mutations, which in turn can prevent cancer from developing.
• Unfortunately, many pecan recipes require a lot of sugar and corn syrup, but there are recipes available that use natural ingredients.

"Referred to as Carya illinoinensis in scientific literature, pecans are a member of the Juglandaceae family, which makes it a relative of the hickory and the walnut. Pecans are also considered native to North America; their existence has predated even the earliest human settlements."

Read more: https://www.naturalnews.com/2018-06-11-the-health-benefits-of-eating-pecans.html

Cortisol is a hormone that is released whenever we are under intense levels of stress. Whenever you are in a situation that causes extreme tension, your brain reacts with what is called a, "fight or flight" response. This response is what contributes to heightened cortisol levels. Elevated cortisol can lead to various health conditions, so it is important to keep it regulated by consuming an anti-inflammatory diet, and by participating in activities that reduce stress such as meditation.

Key Takeaways:

• To keep your cortisol levels low, switch to a diet that is low in processed foods and high in nutrients, antioxidants, and fiber.
• Relieve stress with techniques such as meditation, deep breathing exercises, acupuncture, and spending time with nature.
• Be sure to exercise regularly and get enough sleep to keep your hormones in balance.

"Although most think of cortisol as a bad thing — such as contributing to acne, weight gain or high blood pressure — there’s actually a lot more to cortisol levels than just our stress response and its unwanted symptoms."

Read more: https://draxe.com/cortisol-levels/

Consuming chilled yerba mate can enable humans to burn over 50% more calories than they would without drinking it! This boost in energy expenditure not only relates to more fat loss, but it also helps regulate and improve the cardiovascular system. A study that included 23 participants concluded these findings, showing just how beneficial the consumption of chilled yerba mate is much more useful to the body than simply consuming hot varieties of herbal teas.

Key Takeaways:

• A drink needs to reach your body's natural temperature in order to digest it as is. When something is colder, it burns energy while digesting the product.
• Not only can yerba mate help decrease body fat when you have it cold, but it also contains much less sugar than other tea drinks.
• The antioxidant properties that are present within yerba mate will still be contained when it is in a chilled form.

"Data from the study showed that iced yerba mate tea produced over 50 percent more energy expenditure, or calorie burning, versus hot tea, or 8.3 percent compared to 3.7 percent."

Read more: https://www.naturalnews.com/2018-06-14-drinking-chilled-yerba-mate-can-help-you-achieve-your-weight-loss-goals.html

The presence of heavy metals within your body can lead to some pretty damaging effects such as increasing your ALT and AST levels which are indicators of your liver function. Fortunately, probiotics such as synbiotic can help regulate your system in order to promote more balance and less heavy metals within your system. Getting probiotics through a synbiotic diet is a great way to remove the presence of metals within you due to how easy it is to consume within a daily diet.

Key Takeaways:

• A supplement called a synbiotic can give you the probiotics that your body needs to eliminate heavy metals.
• You can also get more synbiotic in your system by just participating in the synbiotics diet.
• When you take synbiotics, you are getting both probiotic and prebiotic components.

"The beneficial effects of probiotic bacteria are boosted by the addition of prebiotics that promotes their growth."

Read more: https://www.naturalnews.com/2018-07-06-probiotics-remove-heavy-metals-from-your-body.html

Are you one of many people who are trying to lose weight. Here are several bad bedtime habits that might be standing in your way of reaching that goal. Ignore your craving for a late night snack. Some researchers believe that insufficient sleep can affect weight too. That includes staying off any devices, like your phone, laptop or tablet. Avoiding caffeine at night will help you sleep as well. Also, sleep with the light off and get regular exercise to regulate your body for sleep.

Key Takeaways:

• Eating late at night has been shown to increase insulin levels and cholesterol levels, besides being implicated in weight gain.
• Two significant hormones that help to regulate appetite are thrown off balance when you don't get sufficient sleep.
• The blue light on our devices, which are good for increasing focus, are conversely poor for inducing sleep and should be avoided before slumber-time.

"Believe it or not, your bedtime routine may be a contributing factor to your weight gain, but the good news is that by adjusting your routine slightly you can get back on track to reach your desired goal weight."

Read more: https://www.healthnutnews.com/the-bedtime-mistakes-that-are-making-you-gain-weight/

Although hard evidence about the effects of cannabinoids like CBD is difficult to come by, our growing understanding of the body's natural endocannabinoid systems suggest that there is at least the potential for benefits from CBD for athletic performance. CBD, for example, may help boost the endocannabinoid system's suppression of pain and inflammation. However, it is also important to note that THC, the psychoactive ingredient in whole marijuana, appears to decrease long-range endurance. More research is sorely needed to understand just how CBD and other cannabinoid compounds impact athletic performance.

Key Takeaways:

• A component called endocannabinoids is found in CBD oil which can help regulate brain function.
• CBD oil is a more viable option for athletics as THC can really hinder levels of endurance.
• CBD oil has not been proven to change a person's heart rate or blood pressure during physical activity yet.

"Despite anecdotal evidence that CBD oil might help with athletic performance and recovery, there actually haven't been any clinical trials examining those effects, says Brook Henry, PhD, an assistant research scientist at the University of California, San Diego's Center for Medical Cannabis Research and department of psychiatry."

Read more: https://www.refinery29.com/cbd-oil-for-exercise

Asparagus does more than just help promote digestive health. It also is known for containing something called rutin, which is a flavonoid that has the ability to help reduce the risk of blood clots. Studies with rats have also shown that consumption of asparagus over a ten week time span can result in more regulated blood pressure in those who are suffering from hypertensive symptoms. Asparagus also contains glutathione, which is known for boosting the human immune system.

Key Takeaways:

• Fiber is known for helping cardiovascular health in humans, so the fiber content in asparagus can contribute to heart health.
• Asparagus is high in folate levels which is essential in helping fetuses thrive while in-utero.
• Asparagus is also high in potassium levels which can help regulate blood pressure.

"Asparagus is a low-calorie vegetable rich in antioxidants, minerals and anti-inflammatory properties. Asparagus also contains rutin – a flavonoid that helps to treat haemorrhoids and prevent blood clots."

Read more: http://www.longevitylive.com/anti-aging-beauty/anti-aging-health-studies/asparagus-superfood/

Taking control of your diet, specifically your blood sugar, has been known for a long time as a key to long term health. It can help regular your chance for stroke, heart disease and diabetes, but regulating your blood sugar may also help with stopping dementia according to recent research. Focusing on what you take in will be key as you get older. Stick with whole grains and vegetables, and stay away from heavy starches and sugars to help your body maintain itself long into life.

Key Takeaways:

• Watching what we eat and avoiding smoking are two ways to help our brain stay healthy as we age.
• Use of the natural components of CuraLin may be one way to regulate sugar levels in the body.
• Eating some protein with every meal is another nutritious way to prevent sugar binges and keep glucose levels steady.

"DIABETES patients in old age are more likely to suffer from long-term deterioration in their memory and thinking skills than those who have normal blood sugar levels, according to a new study."

Read more: https://www.express.co.uk/life-style/health/911522/diabetes-dementia-symptoms-signs-test

This article is a very informative piece on the health of the gut. Talks about all the bacteria in the gut and the way it affects your body. The bacteria in the body that need to be regulated to be healthy and how to put the correct bacteria into your body. Also gives you some macrobiotics options that put the proper bacteria into your body and helps you maintain a healthy gut in the process.

Key Takeaways:

• The gut is not the most exciting part of the body but it's generating a lot of interest at the moment.
• The ability to lose weight can be directly linked to the health of your gut as it's responsible for controlling the amount of calories you absorb.
• Specialist foods, such as the Super 8, can help keep your gut in tip top condition to maintain peak performance and keep you healthy.

"Your levels of ‘good’ bacteria can be altered by many things including poor diet, antibiotics, stressful situations, low quality food, travel tummy, and ageing."

Read more: http://www.advertiser.ie/galway/article/95088/the-benefits-of-a-healthy-gut

There is a steep cost to sleep deprivation. People need to get plenty of sleep at night, or they will suffer the consequences. Sleep deprivation does the same thing to your body as physical stress does and even illness. It is something to avoid. If you do not get enough sleep then you are putting yourself at risk of developing some bad diseases. Sleeping is also an important thing for our emotional balance. Fatigue hinders your ability to regulate emotions.

Key Takeaways:

• Besides health issues, sleep is important to maintain a stable mental balance.
• And taking sleeping bills is dangerous to your overall health as bill users have a 35% higher risk for certain cancers.
• Poor or lack of sleep leads to increased risk of car accidents, reduced productivity and obesity.

"Cutting just one hour of sleep a night increases the expression of genes associated with inflammation, immune excitability, diabetes, cancer risk and stress."

Read more: https://www.healthnutnews.com/the-steep-cost-of-sleep-deprivation/

Researchers have shown that lactic acid bacteria (LAB) may provide broad protection against influenza viruses. LAB are best known for their human gut floral maintenance, fermentative activity, and preservative capacity. LAB are widely used in food industry, such as in the preparation of fermented dairy products, pickling of vegetables, and baking. LAB have many health benefits, such as alleviation of diarrhea, stimulation of immune system, inhibition of infections, and prevention of certain diseases. So, LAB have been classified as probiotics. Previous studies have suggested that many LAB strains protect mice against influenza virus. The aim of the new study is to further explore the antiviral effect of LAB.

Key Takeaways:

• The current seasonal vaccines are readily available but only work well when when vaccine strains and circulating influenza viruses are well matched.
• The probiotics commonly used to regulate digestive issues can potentially offer protection agains Influenza A
• After testing on mice in labs, they are beginning to feel confident that these probiotics can be offered in a nasal spray to humans.

"Our study provides evidence that heat-killed lactic acid bacteria could potentially be administered via a nasal spray as a prophylactic drug against non-specific influenza virus infections."

Read more: https://eurekalert.org/pub_releases/2017-12/gsu-lab121317.php

Veterinarians, researchers and pet owners are looking to loosen federal regulations on the use of marijuana products to help treat sick animals. Medical issues in dogs, such as epilepsy, arthritis, anxiety, loss of appetite and inflammation could potentially by helped by marijuana-based drugs and extracts.

Some people are already using marijuana extracts on their animals, such as those containing CBD, which is an element of marijuana that is not psychoactive. However, such extracts continue to be listed as Schedule 1 drugs by the Federal Drug Enforcement Administration, even when they contain little or no THC. THC is the active component in marijuana that causes intoxication.

The Food and Drug Administration has warned that marijuana products for pets sold in animal hospitals or online pet stores are illegal, since such drugs are unapproved. The FDA has suggested it will pursue legal action against those in violation of the law.

However, the policy-making body of the American Veterinary Medical Association, in conjunction with two group councils, is considering making a recommendation to the DEA for marijuana to be declassified as a Schedule 1 drug in order to enable research for both animal and human medical purposes. Declassification could also help prevent pet owners from accidentally overmedicating their animals in the absence of proper guidance from a medical professional.

In September, Republican senator Orrin Hatch of Utah introduced a bill that would facilitate research on use of marijuana-based medications, concurring that the drug is over-regulated, although he continues to oppose recreational use of the drug,.

Some veterinarians note that without sufficient evidence, it remains unsafe to use marijuana products on animals, with concerns about potential toxicity.

Yet researchers are continuing to wait for clearance to proceed on various relevant studies, such as use of marijuana for dogs with osteoarthritis, pruritis and epilepsy. Some research on use of products with CBD has been stopped until federal approval is granted. Gaining approval has been difficult due to government requirements, which continue to be an obstacle to moving forward.

Key Takeaways:

• people using drugs to reduce pain on their pets. Oils and powders banned.
• D.C standing in the way of the legalization of marijuana for medical purposes.
• FDA making marijuana a schedule 1 drug...hence illegal. You can be arrested for using it.

"The concern our membership has is worry about people extrapolating their own dosages, looking to medicate their pets outside the realm of the medical professional"

Read more: https://www.aspentimes.com/news/scientists-call-on-feds-to-allow-research-on-cbd-for-pets/

Green tea has long been linked to various health benefits such as reduced risk of cancer and heart disease. Green tea is thought to be good for you do to its concentration of flavonoids and catechins. The antioxidants in green tea also could lower your bad cholesterol. Experts recommend drinking a cup of green tea a few times a day. It is possible to drink too much green tea, and that may block iron absorption or cause irritability from the caffeine.

Key Takeaways:

• Flavonoids found in green tea help protect body against cell damage (they are antioxidants)
• Green tea helps regulate cholesterol levels, bringing good cholesterol up and bad cholesterol down
• Decaffeinated green tea comes with healthy benefits too, to those sensitive to caffeine

"An additional benefit for regularly drinking green tea includes a reduced risk for heart disease."

Read more: http://www.thealternativedaily.com/how-much-green-tea-should-i-drink-daily/

Having potassium in your diet regulates calcification of your arteries. Bananas have a lot of potassium, so people should eat plenty of those. Dietary potassium can help to prevent heart issues. Both bananas and avocados can protect against heart disease. They are both foods that are very high in potassium. This is something that the nation needs to pay attention to because a lot of deaths in this country are from heart disease. Potassium matters a lot.

Key Takeaways:

• Potassium-rich foods, like bananas and avocados, could protect against the hardening of arteries that is linked to heart disease.
• This finding comes from a study by University of Alabama researchers using mice as test cases.
• The study suggest that dietary potassium supplements could help prevent heart disease in humans, a major health problem.

"Bananas and avocados -- foods that are rich in potassium -- may help protect against pathogenic vascular calcification"

Read more: https://www.sciencedaily.com/releases/2017/10/171005102712.htm

Cannabidiol oil, or CBD oil, has the potential for use as a treatment of osteoarthritis, inflammatory joint pain, and other related joint pains. CBD is valuable in this regard because it has the potential to, by attaching to CBD1 and CBD2 receptors present in the joints of mammals, reduce the inflammation and pain that patients experience. However, there is still a need for more research. CBD is confirmed to have the potential to solve the issues of pain and inflammation suffered by those with OA, and possibly even prevent OA from developing at all, but as of yet there has been no testing of CBD as a treatment for OA and joint pain.

Key Takeaways:

• Joint synovitis may be caused by inflammation, and over time NSAIDs can cause other health problems.
• Cannabinoids were shown in studies to regulate arthritis and joint disease in humans and animals.
• Findings demonstrate that CBD may relieve joint inflammation which can cause pain.

"In musculoskeletal disease models, systemic administration of CBD suppressed the progression of collagen-induced arthritis by reducing inflammatory cytokine production."

Read more: http://mmjreporter.com/could-cbd-oil-be-used-for-bone-disorders-31091.html

People often go on diets because they want to lose weight. A good way to diet is by just substituting what you eat with healthier things. It's not good to eat much less, though, because your body needs certain nutrients and a certain amount of calories. This tells you what can happen to your brain if you do choose to diet. It might make you think a bit before doing so or at least before choosing an extreme one.

Key Takeaways:

• Body weight is regulated by the brain and this is why diets don't work.When you are on a diet and your weight starts to change, your brain gets this signal and pushes back to maintain the old weight.
• The hypothalamus in your brain controls your body temperature and acts as a thermostat but it also regulates body fat. Your brain establishes, what is referred to, as a set point weight.
• To lower your set point weight over time, eat a healthy diet of unrefined, lower calorie and simple foods. Plus, lower stress and exercise. This will help lower and maintain your weight.

"In fact, though the risks of yo-yo dieting have been contested, one 2016 study found that repeatedly going through these starvation cycles prompts your body to gain more weight."

Read more: https://www.nbcnews.com/better/health/what-happens-your-brain-when-you-go-diet-ncna802626?cid=public-rss_20170920

Okra is a versatile plant that can provide both nutritional as well as health benefits. In terms of cooking, Okra can be prepared to your preference through roasting, boiling, frying or stewing. It can also be steamed to extract a gooey substance that can then be further utilized as a thickener in other recipes.

But Okra also has numerous health benefits as well. It is effective at filtering your blood, aiding in the treatment of kidney deisease. It acts as an antioxidant and is particularly useful in protecting you from liver diseases. It also helps regulate blood sugar levels leading to the belief that it is a viable alternative treatment for those affected by diabetes. It also has been shown to be an effective alternative for treating depression.

But perhaps the most exciting application is the possibility it presents in the treatment of breast cancer. This is currently being studied, but so far it seems that extracts gathered from Okra have shown promise in reducing the growth rate of cancer cells, and in eradicating some existing cancer cells. So this is an exciting development that bears further investigation.

Given the vast list of proven and potential benefits previously listed, Okra seems to be a vegetable that we should all be giving serious consideration to adding to our diets.

Key Takeaways:

• Okra helps to filter blood and create cleaner blood in the body.
• Okra is an antioxidant so it helps to keep the body away from diseases such as liver disease.
• Okra helps to fight depression because it is an antidepressant and can help to increase endorphins.

"Okra extracts were used in a study performed to treat human breast cancer cells due to its high lectin content. The treatment both reduced cancer cell growth by 63 percent and killed 72 percent of the cancer cells."

Read more: https://www.youtube.com/watch?v=PgEOZOi-2Uo